LOCUS       DAVBEO010000001       104130 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 009
            SAMEA1678075-rid20185393.denovo.001, whole genome shotgun sequence.
ACCESSION   DAVBEO010000001 DAVBEO010000000
VERSION     DAVBEO010000001.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678075
            Sequence Read Archive: ERR226392
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 104130)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 104130)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980207.1
            Genome Coverage       :: 150x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:50:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 72 of 147
            Pseudo Genes (incomplete)         :: 72 of 147
            Pseudo Genes (internal stop)      :: 42 of 147
            Pseudo Genes (multiple problems)  :: 32 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..104130
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678075-rid20185393.denovo.001"
                     /strain="KS 009"
                     /db_xref="taxon:1313"
     gene            complement(134..1882)
                     /locus_tag="VQ543_000001"
     CDS             complement(134..1882)
                     /locus_tag="VQ543_000001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2610814.1"
                     /translation="MKRQTVNQTLKRLVVDLANHPFLLFLAFLGTIAQVGLSIYLPIL
                     IGQVIDQVLVAGSSPVFWQIFLQMLLVVIGNTLVQWANPLLYNRLIFSYTRDLRERII
                     HKLHRLPIAFADRQGNGEMVSRVTTDIEQLAAGLTMIFNQFFIGVLMILVSILAMLQI
                     HLLMTLLVLLLTPLSMVISRFIAKRSYHLFQKQTETRGIQTQLIEESLSQQTIIQSFN
                     AQTEFIQRLREAHDNYSGYSQSAIFYSSTVNPSTRFVNALIYALLAGVGAYRIMMGST
                     LTVGRLVTFLNYVQQYTKPFNDISSVLAELQSALACVERIYGVLDSPEVAETGKEVLT
                     SDQVKGAISFKHVSFGYHPEKILIKELSIDIPAGSKVAIVGPTGAGKSTLINLLMRFY
                     PISSGDILLDGQSIYDYTRVSLRQQFGMVLQETWLTQGTIHDNIAFGNPEASREQVIA
                     AAKAANADFFIQQLPQGYDTKLENAGESLSVGQAQLLTISRVFLAIPKILILDEATSS
                     IDTRTEVLVQDAFAKLMKGRTSFIIAHRLSTIQDADLILVLVDGDIVEYGNHQELMDR
                     KGKYYQMQKAAAFSSE"
     gene            complement(1884..3608)
                     /locus_tag="VQ543_000002"
     CDS             complement(1884..3608)
                     /locus_tag="VQ543_000002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2610815.1"
                     /translation="MKHLLSYFKPYIKESILAPLFKLLEAVFELLVPMVIAGIVDQSL
                     PQGDQGHLWMQIGLLLIFAVIGVLVALIAQFYSAKAAVGFAKELTNDLYRHILSLPKD
                     SRDRLTTSSLVTRLTSDTYQIQTGINQFLRLFLRAPIIVFGAIFMAYRISAELTFWFL
                     VMVAILTIVIVGLSRLVNPLYSSLRKKTDQLVQETRQQLQGMRVIRAFGQEKRELQIF
                     QTLNQVYARLQEKTGFLSSLLTPLTYLIVNGTLLVIIWQGYISIQGGVLSQGALIALI
                     NYLLQILVELVKLAMLINSLNQSYISAKRIEEVFAESPENIHSELEQKQVTSGRVLQV
                     QELTFTYPDAAQPSLRDISFDMTQGQILGIIGGTGSGKSSLVQLLLGLYPVDKGNIDL
                     YQNGRSPLNLEQWRSWIAYVPQKVELFKGTIRSNLTLGLNQEVTDQELWQALEIAQAK
                     DFVSDKEGLLDALVEAGGRNFSGGQKQRLSIARAVLRQAPFLILDDATSALDTITESK
                     LLKAIRENLPNMSLILISQRTSTLQMADQILLLEKGELLAVGKHDDLMKSSQVYREIN
                     ASQHGKED"
     gene            complement(3666..4604)
                     /gene="msrB"
                     /locus_tag="VQ543_000003"
     CDS             complement(3666..4604)
                     /gene="msrB"
                     /locus_tag="VQ543_000003"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HET2610816.1"
                     /translation="MAEIYLAGGCFWGLEEYFSRISGVLETSVGYANGQVETTNYQLI
                     KETDHAETVQVIYDEKEVSLREILLYYFRVIDPLSINQQGNDRGRQYRTGIYYQDEAD
                     LPAIYTVVQEQERMLGRKIAVEVEQLRHYILAEDYHQDYLRKNPSGYCHIDVTDADKP
                     LIDAANYEKPSQEVLKASLSEESYRVTQEAATEAPFTNAYDQTFEEGIYVDITTGEPL
                     FFAKDKFASGCGWPSFSRPISKELIHYYKDLSHGMERIEVRSRSGSAHLGHVFTDGPR
                     ELGGLRYCINSASLRFVAKDEMEKAGYGYLLPYLNK"
     gene            complement(4746..4823)
                     /locus_tag="VQ543_000004"
                     /pseudo
     CDS             complement(4746..4823)
                     /locus_tag="VQ543_000004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(4899..5768)
                     /locus_tag="VQ543_000005"
     CDS             complement(4899..5768)
                     /locus_tag="VQ543_000005"
                     /EC_number="2.7.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000692406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine kinase"
                     /protein_id="HET2610817.1"
                     /translation="MKIIVPATSANIGPGFDSVGVAVTKYLQIEVCEERDEWLIEHQI
                     GKWIPHDERNLLLKIALQIVPDLQPRRLKMTSDVPLARGLGSSSSVIVAGIELANQLG
                     QLNLSDHEKLQLATKIEGHPDNVAPAIYGNLVIASSVEGQVSAIVADFPECDFLAYIP
                     NYELRTRDSRSVLPKKLSYKEAVAASSIANVAVAALLAGDMVTAGQAIEGDLFHERYR
                     QDLVREFAMIKQVTKENGAYATYLSGAGPTVMVLASHDKMPTIKAELEKQPFKGKLHD
                     LRVDTKGVRVEAK"
     gene            complement(5770..7056)
                     /locus_tag="VQ543_000006"
     CDS             complement(5770..7056)
                     /locus_tag="VQ543_000006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine dehydrogenase"
                     /protein_id="HET2610818.1"
                     /translation="MTVKIALLGFGTVASGVPFLLKENGGKINQSAHSDIKVAKVLVK
                     DEDEKNRLLAAGNDFNFVTNVDDILSDQDITIVVELMGRIEPAKTFITRALEAGKHVV
                     TANKDLLAVHGAELLEIAQANKVALYYEAAVAGGIPILRTLANSLASDKITRVLGVVN
                     GTSNFMVTKMVEEGWSYDDALAEAQRLGFAESDPTNDVDGIDAAYKMVILSQFAFGMK
                     IAFDDVAHKGIRNITPEDVAVAQELGYVVKLVGSIEETSSGIAAEVTPTFLPKAHPLA
                     SVNGVMNAVFVESIGIGESMYYGPGAGQKPTATSVVADIVRIVRRLNDGTIGKDFNEY
                     SRDLVLANPEDVKANYYFSILALDSKGQVLKLAEIFNAQDISFKQILQDGKEGDKARV
                     VIITHKINKAQLENVSAELKKVSEFDLLNTFKVLGE"
     gene            complement(7207..7944)
                     /gene="mecA"
                     /locus_tag="VQ543_000007"
     CDS             complement(7207..7944)
                     /gene="mecA"
                     /locus_tag="VQ543_000007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000782680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adaptor protein MecA"
                     /protein_id="HET2610819.1"
                     /translation="MKMKQISDTTLKITMSLEDLMDRGMEIADFLVPQEKTEEFFYAI
                     LDELEMPDSFLDTGMLSFRVTPKPDKVDVFVTKSKIDQNLDFEDLSDLPDMEELAQMS
                     PDEFIKTLEKSIADKTKDDIEAIQSLEQVEAKEEEQEQAEQEAESKKEPYIYYILSFA
                     KLADLVAFAKTVTFEMETSELYKMNERYYLTILVDIENHPSPYPAWLLARMREFADDS
                     DISRSVLQEYGQVLMSHDAVLNLQKIG"
     gene            complement(8144..9178)
                     /locus_tag="VQ543_000008"
     CDS             complement(8144..9178)
                     /locus_tag="VQ543_000008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000461501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HET2610820.1"
                     /translation="MFEHYSVADLFANLYKKRKANILALIALFALIAVPFTIKAVRNK
                     NTVKDTTSYSTYLIYKITPPKESAKTILNHQIGGYSDFYGKLIDGNLNGAYLFNDVEP
                     SELKKIASELDTTETTLKNSTNDYWWKKLTVYYMIDDAGVGVKILTSSKDANDLLEKK
                     IDGLIEKFKHAYANVKIEKLETINSKELNANGETALGLNVKNLILRLVVIGVVCVILV
                     VMGNVLVYLFNPTINRVGDFSQYQIDFVTEITTIANLADVLSYKNTGQELTIVSSNKA
                     ILDKLKQSQEALKGMHFVDLQDVSSLLERDTVLLVEEYGVTRYKKFEQSLQILRNLNR
                     SILGVATFKL"
     gene            complement(9207..10640)
                     /locus_tag="VQ543_000009"
     CDS             complement(9207..10640)
                     /locus_tag="VQ543_000009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen polysaccharide polymerase Wzy family
                     protein"
                     /protein_id="HET2610821.1"
                     /translation="MIDGKRLLFSLTIVSYALTLVSGIVYLFNNNNVSLLSTLLFLLV
                     SSLIACWNDIKYYLIHFIFYLTIFVFLVSRPTIDYFRDGALDTYHPIAYRFAFIVVMV
                     SILGLTTGGILARYFIARKKIKVANIGNSLKEVYIKRLRFVSLGVFLLTYPFYFIRLF
                     ERLLYRLQTSYYAYYANFESKLPYFTYILSTFTVYAMCMYLATKPKKLQATAVLVSFI
                     AANTIHLAIGTRNPFILSILFAFVYYFMREQTEKGKWIGFKEKLAIFVGSPILMLAMG
                     VLNYVRDNVQVSHTGFWDILLDFIYKQGTSFGVLARGFLFNSSLPYRDFRNFTFGPVL
                     DYFARGSLGAIFGGKAFEHTTNSVELAIDSNSYAHNLSYLVLNKEYLKGHGIGSSYIM
                     ELYTDYGMIGVFLLSFLLGVLFIAMLQVAYRSRTILFALSLLILNNLFFMPRSSFSES
                     FFNLFTMQFWGIVLVIIFIAKMLTKEN"
     gene            complement(10656..11642)
                     /locus_tag="VQ543_000010"
     CDS             complement(10656..11642)
                     /locus_tag="VQ543_000010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000446977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HET2610822.1"
                     /translation="METALISVIVPVYNVAQYLEKSIASIQKQIYQNLEIILVDDGAT
                     DESGRLCDSIAEQDDRVSVLHKKNEGLSQARNDGMKQAHGDYLIFIDSDDYIHPEMIQ
                     SLYEQLVQEDADVSSCGVMNVYANDESPQSANQDDYFVCDSQTFLKEYLIGEKIPGTI
                     CNKLIKRQIATALSFPKGLIYEDAYYHFDLIKLAKKYVVNTKPYYYYFHRGDSITTKP
                     YAEKDLAYIDIYQKFYNEVVKNYPDLKEVAFFRLAYAHFFILDKMLLDDQYKQFEAYS
                     QIHRFLKGHAFAISRNPIFRKGRRISALALFINISLYRFLLLKNIEKSKKLH"
     gene            complement(11644..12747)
                     /locus_tag="VQ543_000011"
     CDS             complement(11644..12747)
                     /locus_tag="VQ543_000011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000225894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HET2610823.1"
                     /translation="MVAKKKILFFMWSFSLGGGAEKILSTIVSNLDLEKYDIDILEME
                     HFDKGYESVPKHVRILKSLQDYRQTRWLRAFLWRMRIYFPRLTRRLLVKDDYDVEVSF
                     TIMNPPLLFSKRREVKKISWIHGSIEELLKDSSKRESHRSQLDAANTIVGISKKTSNS
                     IKEVYPDYASKLQIIYNGYDFQTILEKSQEKIDIEIAPQSICTIGRIEENKGSDRVVE
                     VIRLLHQEGKNYHLYFIGAGDMEEELKKRVKEYGIEDYVHFLGYQKNPYQYLSQTKVL
                     LSMSKQEGFPGVYVEALSLGLPFISTDVGGAEELSQEGRFGQIIESNQEAAQAITNYM
                     TSASNFDVDEASQFIQQFTITKQIEQVEKLLEE"
     gene            complement(12737..13582)
                     /locus_tag="VQ543_000012"
     CDS             complement(12737..13582)
                     /locus_tag="VQ543_000012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001061982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HET2610824.1"
                     /translation="MNNMTDLKAIQARSLEMAEYFVAFCKEHDLLCYLCGGGAIGALR
                     NKGFIPWDDDLDFFMPRKDYEKLAELWPRYADERYFLSKSHKDFVDRNLFITIRDKET
                     TCIKPYQQDLDLPHGLTLDVLPLDYYPKNPAERKKQVRWALIYSLFCAQTIPEKHGAL
                     MKWGSRILLGLTPKSLRYRIWKKAEKEMTKYDLADCDGITELCSGPGYMRNKYPITSF
                     EDNLFLPFEGTEMPIPIGYDVYLRTAFGDYMTPPPADKQVPHHDAVIADMDKSYTEYK
                     GEYGG"
     gene            complement(13861..15135)
                     /gene="psr"
                     /locus_tag="VQ543_000013"
     CDS             complement(13861..15135)
                     /gene="psr"
                     /locus_tag="VQ543_000013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyisoprenyl-teichoic acid--peptidoglycan
                     teichoic acid transferase Psr"
                     /protein_id="HET2610825.1"
                     /translation="MSKENPLSHHEQLRYDYLLKNIHYLNEREKNEFAYLQEKLTLAR
                     GNSSSSLEQEREEQVDLPSYANRSRSQSKSQALSFPPKKKRRKLRLKRIFMVIFSLLV
                     CVALAMVFMFLRGYQDASAKKTADARAAQVEVFNGQDTRDGVNILIMGTDGRIGQNSV
                     ETRTDSIMVLNVGGSDKKMKLVSFMRDNLVYIDGYSQVINGRKQTDNKLNVAYELGEQ
                     EGQKGAEMVRQVLKDNFDLDIKYYALVDFQAFATAIDTLFPDGVTIDAQFSTLNGRPL
                     TEATVGDDLYATETESPTQTIKVGKQQMNGSTLLNYARFRDDDEADYGRTKRQQQVLT
                     AILEQIKDPTKLFTGSEALGKVFAMTSTNVPYTFLLTNGLSVLDGAKNGIEKLTIPEL
                     GDWVDAYDVYGGLGLLVDQNKYQTKLAQMGLR"
     gene            complement(15132..15980)
                     /gene="pheA"
                     /locus_tag="VQ543_000014"
     CDS             complement(15132..15980)
                     /gene="pheA"
                     /locus_tag="VQ543_000014"
                     /EC_number="4.2.1.51"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HET2610826.1"
                     /translation="MKIAYLGPKGSFSHHVVQTAFPHEELQAFANITDVIKAYEQGLV
                     DYSVVPVENSIEGSVHETLDYLFHQAHIQAVAEIVQPIHQQLMVVPGHTKIEKIFSHP
                     QALAQGKKFIDEQYPEAQIEVTASTAYAARFISEHPDQPFAAVAPRSSAEEYGLELIA
                     EDIQEMEANFTRFWVLGAEKPSIPLQAQTEKMSLALTLPDNLPGALYKALSTFAWRGI
                     DLTKIESRPLKTALGEYFFIIDVDYIDKDLVHFAQKELEAIGIQYKILGAYPIYPISD
                     HGKERR"
     gene            complement(15977..16453)
                     /locus_tag="VQ543_000015"
     CDS             complement(15977..16453)
                     /locus_tag="VQ543_000015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase"
                     /protein_id="HET2610827.1"
                     /translation="MAKVLLGFMGAGKSTIARGLDPNYLDMDALIEKRLGMSIANFFA
                     EKGEAAFRHVESEVLADLLQTDQVVSTGGGVVISQRNRDLLKTNTDNIYLKADFETLY
                     LRIAADKDNQRPLFLNNSKEELVAIFQERQAWYEEVASRVLDVTKLSPEEIIEELR"
     gene            complement(16446..17729)
                     /gene="aroA"
                     /locus_tag="VQ543_000016"
     CDS             complement(16446..17729)
                     /gene="aroA"
                     /locus_tag="VQ543_000016"
                     /EC_number="2.5.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004236106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="HET2610828.1"
                     /translation="MKLKTNIRHLHGSIRVPGDKSISHRSIIFGSLAEGETKVYDILR
                     GEDVLSTMQVFRDLGVEIEDKDGVITIQGVGMAGLKAPQNALNMGNSGTSIRLISGVL
                     AGADFEVEMFGDDSLSKRPMDRVTLPLKKMGVSISGQTERDLPPLRLKGTKNLRPIHY
                     ELPIASAQVKSALMFAALQAKGESVIIEKEYTRNHTEDMLQQFGGHLSVDGKKITVQG
                     PQKLTGQKVVVPGDISSAAFWLVAGLIAPNSRLVLQNVGINETRTGIIDVIRAMGGKL
                     EITEIDPVAKSATLIVESSDLKGTEIGGALIPRLIDELPIIALLATQAQGVTVIKDAE
                     ELKVKETDRIQVVADALNSMGADITPTADGMIIKGKSALHGARVNTFGDHRIGMMTAI
                     AALLVADGEVELDRAEAINTSYPSFFDDLESLIHG"
     gene            complement(17821..18159)
                     /locus_tag="VQ543_000017"
     CDS             complement(17821..18159)
                     /locus_tag="VQ543_000017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000065990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF/YmcA family competence regulator"
                     /protein_id="HET2610829.1"
                     /translation="MSNIYDSANELSRGLRGLPEYKAVKAAKDAIAADAEASKIFTEY
                     LAFQEEIQKLAQTGQMPDASFQAKMEGFGKQIQGNSLLSEFFTKQQQLAIYLSDIEKI
                     VFEPVSELLK"
     gene            complement(18170..19273)
                     /locus_tag="VQ543_000018"
     CDS             complement(18170..19273)
                     /locus_tag="VQ543_000018"
                     /EC_number="1.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydrogenase"
                     /protein_id="HET2610830.1"
                     /translation="MAKTIYIAGLGLIGASMALGIKRDHPDYEILGYNRSQASRDIAL
                     KEGMIDRATDDFASFAPLADVIILSLPIKQTIAFIKELANLDLREGVIISDAGSTKST
                     IVDAAEQYLAGKSVRFVGAHPMAGSHKTGAASADVNLFENAYYIFTPSSLTSQDTLKE
                     MKDLLSGLHARFIEIDAKEHDRVTSQISHFPHILASSLMEQTAVYAQEHEMARRFAAG
                     GFRDMTRIAESEPGMWTSILLSNSETILDRIEDFKERLEVIGQAISKGDEEQIWNFFN
                     QAREQRQTMEIHKRGGVDSSYDLYVDVPDEEDVILRILELLRGTSLVNIHINEENRED
                     IHGILQISFKNAQDLERAEHLITENTDYTVVIK"
     gene            complement(19283..20449)
                     /gene="aroC"
                     /locus_tag="VQ543_000019"
     CDS             complement(19283..20449)
                     /gene="aroC"
                     /locus_tag="VQ543_000019"
                     /EC_number="4.2.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate synthase"
                     /protein_id="HET2610831.1"
                     /translation="MRYLTAGESHGPRLTAIIEGIPAGLPLTAEDINEDLRRRQGGYG
                     RGGRMKIESDQVVFTSGVRHGKTTGAPITMDVINKDHQKWLDIMSAEDIEDRLKSKRK
                     ITHPRPGHADLVGGIKYRFDDLRNSLERSSARETTMRVAVGAVAKRLLAELDMEIANH
                     VVVFGGKEIDVPENLTVAEIKQRAAQSEVSIVNQEREQEIKDYIDQIKRDGDTIGGVV
                     ETVVGGVPVGLGSYVQWDRKLDARLAQAVVSINAFKGVEFGLGFEAGYRKGSQVMDEI
                     LWSKEDGYTRRTNNLGGFEGGMTNGQPIVVRGVMKPIPTLYKPLMSVDIETHEPYKAT
                     VERSDPTALPAAGMVMEAVVATVLAQEILEKFSSDNLEELKEAVAKHRDYTKNY"
     gene            complement(20459..21526)
                     /locus_tag="VQ543_000020"
     CDS             complement(20459..21526)
                     /locus_tag="VQ543_000020"
                     /EC_number="4.2.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydroquinate synthase"
                     /protein_id="HET2610832.1"
                     /translation="MKIRIDIPHHPYDIQIEKGCMAQAGQWLRELWQPQKVVIVTDNH
                     VASLYAEKVKLSLEDAGFQVAVFDFLEGEERKNLTTVQKVYEFLVKQGLTRSDGIVAL
                     GGGVVGDLAGFVASTYMRGIHFVQIPTSLTAQVDSSIGGKTGVNTPFAKNMVGTFAQP
                     DGVLIDPLVLETLGKRELIEGMGEVIKYGLIEDPELWALLTGLNGSVESILEHAETLI
                     EHSCQVKRKMVVEDELDNGIRLYLNFGHTIGHAIEATAGYGKVMHGEAVAMGMVQISK
                     VAEEKGLMPAGITQSITEMCQKFGLPVDYENWKVDKLYQALTHDKKARGNTLKLVLVP
                     ELGSATIHPVSLEEMKDYLVK"
     gene            complement(21545..22399)
                     /locus_tag="VQ543_000021"
     CDS             complement(21545..22399)
                     /locus_tag="VQ543_000021"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HET2610833.1"
                     /translation="MKLDGYTRLAAVVANPIKHSISPFIHNRAFEATATNGAYVAWEI
                     EASDLVETVANIRRYQMFGINLSMPYKEQVIPYLDELSDEARLIGAVNTVVNENGNLI
                     GYNTDGKGFFKCLPSFTISGKKMTLLGAGGAAKSILAQAILDGVSQISVFVRSVSMEK
                     TRPYLDKLQEQTGFKVDLCALEYVSELQARIAESDLLVNATSVGMDGQSSPVPENIVL
                     PETLLVADIIYQPFETPFLKWARSQGNPAVNGLGMLLYQAAEAFQLWTGKKMPTEEIW
                     QSLTEKYQ"
     gene            complement(22389..23066)
                     /locus_tag="VQ543_000022"
     CDS             complement(22389..23066)
                     /locus_tag="VQ543_000022"
                     /EC_number="4.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I 3-dehydroquinate dehydratase"
                     /protein_id="HET2610834.1"
                     /translation="MKLIVSVMPRSLEEAQALDATRYLDADIIEWRADYLPKEAILQV
                     APAIFEKFAGRELVFTLRTRSEGGEIDLSPEEYIHLIKEVAQLYQPDYIDFEYYSYKD
                     VFEEMLDFPNLVLSYHNFQETPENMMEILSELTILNPKLVKVAVMAHTEQDVLDLMNY
                     TRGFKTLNPEQEYVTISMGKVGKVSRITADVTGSSWSFASLDEVSAPGQISLASMKKI
                     REILDEA"
     gene            complement(23063..24226)
                     /locus_tag="VQ543_000023"
     CDS             complement(23063..24226)
                     /locus_tag="VQ543_000023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001837533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent rRNA methyltransferase"
                     /protein_id="HET2610835.1"
                     /translation="MNRIRVSKRVEKKLAKGLVLLEASDLENVNLKDQEVEVQGQEGN
                     FLGTAYLSQQNKGLGWFVSKDKVAFNQAFFETLFRKAKEKRNAYYQDDLTTAFRLFNQ
                     EGDGFGGLTVDLYGDYAVFSWYNSYVYQIRQTISEAFRQVFPEVLGAYEKIRFKGLDY
                     ESAHVYGQEAPDFFTVLENGVLYQVFMNDGLMTGIFLDQHEVRGSLVDGLAMGKSLLN
                     MFSYTAAFSVAAAMGGASQTTSVDLAKRSRELSQAHFQANGLSTDERRFIVMDVFEYF
                     KYAKRKNLTYDVIVLDPPSFARNKKQTFSVAKDYHKLISQSLEILNPGGIIIASTNAA
                     NVSRQKFTEQIDKGFAGRSYQILNKYGLPADFAYNKKDESSNYLKVISMKVSK"
     gene            complement(24911..26545)
                     /locus_tag="VQ543_000024"
                     /pseudo
     CDS             complement(24911..26545)
                     /locus_tag="VQ543_000024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001237556.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(26526..27275)
                     /locus_tag="VQ543_000025"
     CDS             complement(26526..27275)
                     /locus_tag="VQ543_000025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000569185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2610836.1"
                     /translation="MIEFQNVSKLYGDKEALSNLNLQIENGEIMGLIGHNGAGKSTTI
                     KSLVSIISPSSGRILVDGQELSENRLAIKRKIGYVADSPDLFLRLTANEFWELIASSY
                     DLTSSDLETSLARLLNVFDFAENRYQVIETLSHGMRQKVFVIGALLSAPDIWVLDEPL
                     TGLDPQAAFDLKQMMKEHAQKGKTVLFSTHVLEVAEQVCDRIAILKKGHLIYCGSVEN
                     LRKDHPDQFLESIYLSLAGRKEEVADASQGH"
     gene            27454..28908
                     /locus_tag="VQ543_000026"
     CDS             27454..28908
                     /locus_tag="VQ543_000026"
                     /EC_number="3.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-amylase"
                     /protein_id="HET2610837.1"
                     /translation="MQNQTLMQYFEWYLPHDGQHWTRLAENAPHLAHLGISHVWMPPA
                     FKATNEKDVGYGVYDLFDLGEFNQKGTVRTKYGFKEDYLQAIQALKEQGIQPMADVVL
                     NHKAAADNREAFQVIEVDPVDRTVELGEPFTINGWTSFTFDGRQDTYNGFHWHWYHFT
                     GTDYDAKRSKSGIYLIQGDNKGWANEELVDNENGNYDYLMYADLDFKHPEVIQNIYDW
                     ADWFMETTGVAGFRLDAVKHIDSFFMRNFIRDMKEKYGDDFYVFGEFWNPDKEANLDY
                     LEKTEEHFDLVDVRLHQNLFEASQAGANYDLRGIFTDSLVELKPDKAVTFVDNHDTQR
                     GQALESTVEEWFKPAAYALILLRQDGLPCVFYGDYYGISGQYAQEDFKEILDRLLAIR
                     KDLAYGEQNDYFDHANCIGWVRSGAENQSPIAVLISNDQENSKSMFVGQEWTNQTFVD
                     LLGNHQGQVTIDEEGYGQFPVSARSVSVWAVNTI"
     gene            complement(28998..31616)
                     /gene="alaS"
                     /locus_tag="VQ543_000027"
     CDS             complement(28998..31616)
                     /gene="alaS"
                     /locus_tag="VQ543_000027"
                     /EC_number="6.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012130635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--tRNA ligase"
                     /protein_id="HET2610838.1"
                     /translation="MKQLSSAQVRQMWLDFWATKGHSVEPSVSLVPVNDPTLLWINSG
                     VATLKKYFDGTIIPENPRITNAQKAIRTNDIENVGKTARHHTMFEMLGNFSIGDYFRD
                     EAITWAYELLISPEWFDFPAEKLYMTYYPDDKDSYNRWIEVGVDPSHLIPIEDNFWEI
                     GAGPSGPDTEIFFDRGEAFDPENIGLRLLAEDIENDRYIEIWNIVLSQFNADPAVPRS
                     EYKELPHKNIDTGAGLERLVAVIQGAKTNFETDLFMPIIREVEKLSGKVYDQDGDNMS
                     FKVIADHIRSLSFAIGDGALPGNEGRGYVLRRLLRRASMHGQKLGINEPFLYKLVPTV
                     GKIMESYYPEVLEKRDFIEKIVKSEEESFARTLHSGQHFAQGIVADLKEKGQSVIAGS
                     DVFKLYDTYGFPVELTEEIAEEAGMTVDREGFEAAMKEQQERARASAVKGGSMGMQNE
                     TLQNITVESVFNYNTSQLSSKLVAIVADNAEVGAVSEGTASLIFAETSFYAEMGGQVA
                     DYGQILDESGKIVATVTNVQKAPNGQALHTVEVLAPLALNQEYTLAIDSNRRHRVMKN
                     HTATHLLHAALHNILGNHATQAGSLNEVEFLRFDFTHFQAVTAEELRAIEQQVNEKIW
                     EALEVKTVETDIDTAKEMGAMALFGEKYGKEVRVVTIGDYSIELCGGTHVGNTSEIGL
                     FKIVKEEGIGSGTRRILAVTGKEAFEAYREQEDALKAVAATLKAPQVKEVPHKVEGLQ
                     EQLRQLQKENAELKEKAAAAAAGDIFKDAKEVNGHRYIASQVSVSDAGALRTFADNWK
                     QKDYSDLLVLVAAIGDKVNVLVASKTKDLHAGNLVKELAPIIDGRGGGKPDMAMAGGS
                     NQAKIQELLDAVAGKL"
     gene            complement(31638..32123)
                     /locus_tag="VQ543_000028"
     CDS             complement(31638..32123)
                     /locus_tag="VQ543_000028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000847073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LURP-one-related family protein"
                     /protein_id="HET2610839.1"
                     /translation="MKTFLVKQKFRLGGERFAIKDDRGEIAYQVEGSFFKIPKTFTIY
                     DAAGEQVSQISKEILTLLPRFEIQLLDGSSFVIRKKLTFWRDKYEFDNLGLRIEGNIW
                     DLNFKLLDDRDQLIAEIKKELFHLTSTYTVTVLEDAYADLVISLCVAIDYVEMLESQS
                     H"
     gene            complement(32398..32637)
                     /locus_tag="VQ543_000029"
     CDS             complement(32398..32637)
                     /locus_tag="VQ543_000029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000784186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2610840.1"
                     /translation="MKMSTFFNKSFWPTFMIVNQTAILFHLKDGLDRQYLTTESIYWV
                     IGTFIFGNILVAVFSNMKIWDKKKNGSKKKYILEK"
     gene            complement(32890..33960)
                     /locus_tag="VQ543_000030"
     CDS             complement(32890..33960)
                     /locus_tag="VQ543_000030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HET2610841.1"
                     /translation="MKKIYSFLAGIAAIILVLWGIATHLDSKINSRDSQKLVIYNWGD
                     YIDPELLTQFTEETGIQVQYETFDSNEAMYTKIKQGGTTYDIAIPSEYMINKMKDEDL
                     LVPLDYSKIEGIENIGPEFLNQSFDPGNKFSIPYFWGTLGIVYNETMVDEAPEHWDDL
                     WKPEYKNSIMLFDGAREVLGLGLNSLGYSLNSKDLQQLEETVDKLYKLTPNIKAIVAD
                     EMKGYMIQNNVAIGVTFSGEASQMLEKNENLRYVVPTEASNLWFDNMVIPKTVKNQDS
                     AYAFINFMLKPENALQNAEYVGYSTPNIPAKELLPEETKEDKAFYPDVETMKHLEIYE
                     KFDHKWTGKYSDLFLQFKMYRK"
     gene            complement(33957..34730)
                     /locus_tag="VQ543_000031"
     CDS             complement(33957..34730)
                     /locus_tag="VQ543_000031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET2610842.1"
                     /translation="MKKFANLYLGLVFLVLYLPIFYLIGYAFNAGDDMNSFTGFSWTH
                     FETMFGDGRLMLILAQTFFLAFLSALIATIIGTFGAIYIYQSRKKYQEAFLSLNNILM
                     VAPDVMIGASFLILFTQLKFSLGFLTVLSSHVAFSIPIVVLMVLPRLKEMNGDMIHAA
                     YDLGASQFQMFKEIMLPYLTPSIITGYFMAFTYSLDDFAVTFFVTGNGFSTLSVEIYS
                     RARKGISLEINALSALVFLFSIILVVGYYFISREKEEQA"
     gene            complement(34727..35533)
                     /locus_tag="VQ543_000032"
     CDS             complement(34727..35533)
                     /locus_tag="VQ543_000032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET2610843.1"
                     /translation="MKKTSSKLFVVPYMLWIALFVLAPLVLIFGQSFFNIEGQFSLEN
                     YKSYFASQNLTYLKMSFNSVLYAGIVTFVTLLISYPTALFLTRLKHRQLWLMLIILPT
                     WINLLLKAYAFIGIFGQNGSINQFLEFIGIGSQQLLFTDFSFIFVASYIELPFMILPI
                     FNVLDDMDNNLINASYDLGATKWETFRHVIFPLSMNGVRSGVQSVFIPSLSLFMLTRL
                     IGGNRVITLGTAIEQNFLTNDNYGMGSTIGVILILTMFITMWVTKERRER"
     gene            complement(35514..36671)
                     /locus_tag="VQ543_000033"
     CDS             complement(35514..36671)
                     /locus_tag="VQ543_000033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018372333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2610844.1"
                     /translation="MKKPIIEFKNVSKVFEDSNTKVLKDINFELEEGKFYTLLGASGS
                     GKSTILNIIAGLLDATTGDIMLDGVRINDIPTNKRDVHTVFQSYALFPHMNVFENVAF
                     PLRLRKIDKKEIEQRVAEVLKMVQLEGYEKRSIRKLSGGQRQRVAIARAIINQPRVVL
                     LDEPLSALDLKLRTDMQYELRELQQRLGITFVFVTHDQEEALAMSDWIFVMNDGEIVQ
                     SGTPVDIYDEPINHFVATFIGESNILPGTMIEDYLVEFNGKRFEAVDGGMKPNEPVEV
                     VIRPEDLRITLPEEGKLQVKVDTQLFRGVHYEIIAYDELGNEWMIHSTRKAIVGEEIG
                     LDFESEDIHIMRLNETEEEFDARIEEYVEIEEQEAGLINAIEEERDEENKL"
     gene            complement(36730..37680)
                     /gene="murB"
                     /locus_tag="VQ543_000034"
     CDS             complement(36730..37680)
                     /gene="murB"
                     /locus_tag="VQ543_000034"
                     /EC_number="1.3.1.98"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000116191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate dehydrogenase"
                     /protein_id="HET2610845.1"
                     /translation="MSVREKMLEILEGIDIRFQEPLHSYSYTKVGGEADYLVFPRNRF
                     ELARLVKFANQENIPWMVLGNASNIIVRDGGIRGFVILCDKLNNVSVDGYTIEAEAGA
                     NLIETTRIALRHSLTGFEFACGIPGSVGGAVFMNAGAYGGEIAHILQSCKVLTKDGEI
                     ETLSAKDLAFGYRHSAIQESGAVVLSVKFALAPGTHQVIKQEMDRLTHLRELKQPLEY
                     PSCGSVFKRPVGHFAGQLISEAGLKGYRIGGVEVSEKHAGFMINVADGTAKDYEDLIQ
                     SVIEKVKEHSGITLEREVRILGESLSVAKMYAGGFTPCKR"
     gene            complement(37792..38544)
                     /locus_tag="VQ543_000035"
     CDS             complement(37792..38544)
                     /locus_tag="VQ543_000035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000152219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhfC family intramembrane metalloprotease"
                     /protein_id="HET2610846.1"
                     /translation="MTIHIIITMLLLLAFLIGSIWFAKKKYQINLAVLGLGAVAFFVS
                     SQILEKLVHILILHPQKDGSIALLQDHPLIYIIYGLAMAAFFEETARLVFFKWFEKKR
                     SLEKADALAYGLGHGGLELIFLGLTSLLNLYIVLSAVQTQNPQVMQLLSENMLKTIQS
                     LSVWQIYLLGFERILALGFQLLLTVWVYQAVRQKKWIYLLTAYGLHAFFDLAPSLFQV
                     GWLTNPVLVEVILALELVLVAYGTKEIFCKKS"
     gene            complement(38554..39285)
                     /gene="budA"
                     /locus_tag="VQ543_000036"
     CDS             complement(38554..39285)
                     /gene="budA"
                     /locus_tag="VQ543_000036"
                     /EC_number="4.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000360290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate decarboxylase"
                     /protein_id="HET2610847.1"
                     /translation="MDKNVQEPVKLFQYNTLGALMAGLYGGTMTVGELLEHGDLGLGT
                     LDSIDGELIVLDGKAYQAKGSGDQPEIVEVSPDALIPYAAVVPHQAEVIFRQRFEMTD
                     KELKERIESYYDGENLFRSIKIRGEFLHMHVRMIPKSTPDTKFADVATHQPEYSRDNV
                     AGTIVGFWTPEIFHGVSVAGYHLHFISDDLTFGGHVMDFVIKEGIIEVGAVDQLDQRF
                     PVQDRQYLFAKFNVDEMKKDIEKAE"
     gene            39427..40698
                     /locus_tag="VQ543_000037"
     CDS             39427..40698
                     /locus_tag="VQ543_000037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HET2610848.1"
                     /translation="MKKQSKYKEVVSYLKNGIESGRFPTGSRLPSIRQLSLDFHCSKD
                     TIQRALLELRHEQYLYAKPQSGYYVLEQGQHQDLEIEVTDEHASAYDDFRLCVNETLI
                     GRENYLFNYYDNQEGLEDLRQSIHKLLFEQALYCKANQLVLTSGTQQALFILSQISFP
                     RQAKEILVEQPTYHRMNRLLIAQGLDYQTIERGIDGIDLEELEGHFKTGKIKFFYTIP
                     RFHYPLGHSYSEQDKRSILNLAAKYDVYIVEDDYLGDLDSKKGQTFHYLDTEEHVIYI
                     KSFSTSLFPALRITALILPNAIKEAFVAYKNILDYDSNLIMQKALSLYIDSQLFEKNR
                     LARLTNHESYQKQIEERITKTPCPLPHYPLHDGLLLDLRQYPKIASLKHSQLGLDFFE
                     EAYLSTCPYQFAKVSLDNLENVLNYLKAELE"
     gene            complement(40718..41533)
                     /locus_tag="VQ543_000038"
     CDS             complement(40718..41533)
                     /locus_tag="VQ543_000038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000837371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HET2610849.1"
                     /translation="MKSKKWIFVLCNFLASFFLVACQSGSNGSQSAVEAIKQKGKLVV
                     ATSPDYAPFEFQSLVDGKNQVVGADIDMAQAIADELGVKLEILSMSFDNVLTSLQTGK
                     ADLAVAGISATDERKEVFDFSIPYYENKISFLVRKADVEKYKDLTSLESANIAAQKGT
                     VPESMVKEQLPKAQLTSLTNMGEAVNELQAGKIDAVHMDEPVALSYAAKNAGLAVATV
                     SLKMKDGDANAVALRKNSDDLKEVVDKVIQKLKDEGTYQSYLEKAASLTEVEE"
     gene            complement(41690..42343)
                     /gene="phoU"
                     /locus_tag="VQ543_000039"
     CDS             complement(41690..42343)
                     /gene="phoU"
                     /locus_tag="VQ543_000039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000946475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HET2610850.1"
                     /translation="MLRSQFEEDLEKLHNQFYAMGQEVLSQINRTVRAFVTHDRDLAK
                     EVIEDDAEVNEYEVKLEKKSFEMIALQQPVSQDLRTVLTVLKAVSDVERMGDHAVAIA
                     QATIRMKGEERIPAVEEEIKKMGREVKSVVEAALDLYLNGSVDDAYRVASMDEQINHY
                     FETIRDLATEEIKKNPEAIVTGRDYFQVISYLERIGDYAKNICEWVVYFETGKIVEL"
     gene            complement(42355..43113)
                     /gene="pstB"
                     /locus_tag="VQ543_000040"
     CDS             complement(42355..43113)
                     /gene="pstB"
                     /locus_tag="VQ543_000040"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014713134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HET2610851.1"
                     /translation="MTDAILQVSDLSVYYNKKKALNSVSLSFQPKEITALIGPSGSGK
                     STLLKSLNRMGDLNPEVTTTGSVVYNGHNIYSPRTDTVELRKEIGMVFQQPNPFPMTI
                     YENVVYGLRINGIKDKQVLDEAVEKALQGASIWDEVKDRLYDSAIGLSGGQQQRVCVA
                     RVLATSPKIILLDEPTSALDPISAGKIEETLYGLKDKYTMLLVTRSMQQASRISDKTG
                     FFLDGDLIEFNDTKQMFLDPQHKETEDYITGKFG"
     gene            complement(43126..43929)
                     /gene="pstB"
                     /locus_tag="VQ543_000041"
     CDS             complement(43126..43929)
                     /gene="pstB"
                     /locus_tag="VQ543_000041"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000852852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HET2610852.1"
                     /translation="MSTYNWDEKHILTFPEEKVALSTKDVHVYYGKNESIKGIDMQFE
                     RNKITALIGPSGSGKSTYLRSLNRMNDTIDIAKVTGQILYRGIDVNRPEINVYEMRKH
                     IGMVFQRPNPFAKSIYRNITFAHERAGVKDKQVLDEIVETSLRQAALWDQVKDDLHKS
                     ALTLSGGQQQRLCIARAISVKPDILLMDEPASALDPIATMQLEETMFELKKNFTIIIV
                     THNMQQAARASDYTGFFYLGDLIEYDKTATIFQNAKLQSTNDYVSGHFG"
     gene            complement(43940..44824)
                     /gene="pstA"
                     /locus_tag="VQ543_000042"
     CDS             complement(43940..44824)
                     /gene="pstA"
                     /locus_tag="VQ543_000042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009443446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HET2610853.1"
                     /translation="MRAKKLDKLATAVLYTIASIIVTILASLILYILVRGLPHISWSF
                     LTGRSSAFQAGGGIGIQLYNSFFLLVITLIISVPLSMGAGIYLAEYAKKGPVTNFVRT
                     CIEILSSLPSVVVGLFGYLIFVVQFEYGFSIISGALALTVFNLPQMTRNVEDSLKHVH
                     HTQREAGLALGISRWETVVHVVIPEALPGIVTGVVLASGRIFGEAAALIYTAGQSAPA
                     LDWSNWNILSVTSPISIFRQAETLAVHIWKVNSEGTIPDGTIVSAGSAAVLLIFILIF
                     NFGARKFGSYLHKKLTAA"
     gene            complement(44814..45731)
                     /gene="pstC"
                     /locus_tag="VQ543_000043"
     CDS             complement(44814..45731)
                     /gene="pstC"
                     /locus_tag="VQ543_000043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018378778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HET2610854.1"
                     /translation="MNQEELAKKMLLPSKNSRLEKLGKGLTFACLSLIVILVAMILVF
                     VAQKGLSTFFVNGVNIFDFLLGGTWNPSSKEFGALPMILGSFIVTILSALIATPFAIG
                     AAVFMTEVSPKGAKILQPAIELLVGIPSVVYGFIGLQVVVPFVRSVFGGTGFGILSGI
                     SVLFVMILPTVTFMTTDSLRAVPRYYREASFAMGATRWQTIWRVILKAARSGIFTAVV
                     FGMARAFGEALAIQMVVGNSAVIPTSLTTPAATLTSILTMGIGNTVMGTVNNNVLWSL
                     ALVLLLMSLVFNSVIKLITKERGKKNYAR"
     gene            complement(45731..46609)
                     /gene="pstS"
                     /locus_tag="VQ543_000044"
     CDS             complement(45731..46609)
                     /gene="pstS"
                     /locus_tag="VQ543_000044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS"
                     /protein_id="HET2610855.1"
                     /translation="MKKRKKLALSLIAFWLTACLVGCASWIDRGESITAVGSTALQPL
                     VEVAADEFGTIHVGKTVNVQGGGSGTGLSQVQSGAVDIGNSDVFAEEKDGIDASALVD
                     HKVAVAGLALIVNKEVDVDNLTTEQLRQIFIGEVTNWKEVGGKDLPISVINRAAGSGS
                     RATFDTVIMEGQSAMQSQEQDSNGAVKSIVSKSPGAISYLSLTYIDDSVKSMKLNGYD
                     LSPENISSNNWPLWSYEHMYTLGQPNELAAEFLNFVLSDETQEGIVKGLKYIPIKEMK
                     VEKDAAGTVTVLEGRQ"
     gene            complement(47183..48487)
                     /locus_tag="VQ543_000045"
     CDS             complement(47183..48487)
                     /locus_tag="VQ543_000045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001160253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RsmF rRNA methyltransferase first C-terminal
                     domain-containing protein"
                     /protein_id="HET2610856.1"
                     /translation="MKFPEGFVEKYKEILGDEARDFLASFEEEAVSAFRVNPLKEEQL
                     SFSDAITQTPWGHYGKVSGKSPEHATGLVYSQEPAAQMVAQVAQPSPGMKVLDLAAAP
                     GGKSTQLAAYLAGEGLLVSNEISSKRAKILVENMERFGATNVVVTNESADRLVKVFKG
                     YFDLIVLDAPCSGEGMFRKQPDAMDYWSLDYPSQCASLQREILEDAVTMLAEGGRLVY
                     STCTWAPEENEEIVNWLLEEYDFDLLPVEHINGMVAGIDLPETARMYPHQFKGEGQFV
                     AHLQFKGNNPAPKFKASKSNLSREQVALWQEFAQNHLKVNLPGILQIFGDQLYLLPEL
                     LPDLGKLKIARNGLHLGTFKKKRFEPSFALGLALKPSQVEQSVEIGQEEFVKYAAGET
                     VQLAESLPNGWYQVLVKGNGLGFAKVTGNVLKNYFPKGLRFK"
     gene            complement(48488..49261)
                     /locus_tag="VQ543_000046"
     CDS             complement(48488..49261)
                     /locus_tag="VQ543_000046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inositol monophosphatase family protein"
                     /protein_id="HET2610857.1"
                     /translation="MKSKFEFAKELVKKAGQYILDHMQEDLRVETKSSPTDLVTRLDK
                     EVQELLVGEILSRYPEDKICAEEGCLRASVQEGKVWVIDPIDGTNNFVAQQEDFAVMM
                     AYFENGQGQFGLIYDVVKGDCYHGGGEFPVCLNDRPLASFKTKPLGDFLIAGNSGMLE
                     TNEWGLADLSRAVLGVRVYGSAAISFAKILSGRLLTYLTYLQPWDYAAASILGESLGY
                     RVVTLFGEAPDFQTRQPVMMVPLEMQEEIQSYIYERKRT"
     gene            complement(49251..49529)
                     /locus_tag="VQ543_000047"
     CDS             complement(49251..49529)
                     /locus_tag="VQ543_000047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002895777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0223 family protein"
                     /protein_id="HET2610858.1"
                     /translation="MNKQYSYPLDLSWSTEELASVLSFFNDVEAAYEGKVEAKKLLDS
                     YKGFKAVVPSKSEEKRLGREFETVSGYSLYRAVQAAKEKGKGKISLEK"
     gene            complement(49529..49930)
                     /locus_tag="VQ543_000048"
     CDS             complement(49529..49930)
                     /locus_tag="VQ543_000048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007556665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HET2610859.1"
                     /translation="MITLFLSPSCTSCRKAKTWLEKHKVPFVEHNIMTSPLTRKELQH
                     ILSLTENGTDDIISTRSKIFQKLNIDVESISVSELLHLIEQYPSLLRRPIIIDAKRMQ
                     IGFNEDEIRAFLPRSYRKQELKEARMRAGIS"
     gene            complement(50140..50757)
                     /locus_tag="VQ543_000049"
     CDS             complement(50140..50757)
                     /locus_tag="VQ543_000049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01906 family membrane protein"
                     /protein_id="HET2610860.1"
                     /translation="MKTKLTFWGSMLFLLSLSILLTIYLAWIFYPMEIQWLNLTNRVY
                     LKPETIQYNFHILMNYLTNPFSQVLQMPDFRSSAAGLHHFAVVKNLFHLVQLVALVTL
                     PSFYVFVNRIVKKDFLSLYRKSLLALVVLPVMIGLGGVLIGFDQFFTLFHQILFVGDD
                     TWLFDPAKDPVIMILPETFFLHAFLLFFALYESFFGYLCLKSRRK"
     gene            complement(50747..51520)
                     /locus_tag="VQ543_000050"
     CDS             complement(50747..51520)
                     /locus_tag="VQ543_000050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01457 family HAD-type hydrolase"
                     /protein_id="HET2610861.1"
                     /translation="MKYKGYLIDLDGTIYKGKDQIPAGETFVHELQKRDIPYLFVTNN
                     TTRTPESVKEMLAQNFNIDTPLSTVYTATLATIDYMNDLGLEKTVYVVGEAGLKEAIK
                     AAGYVEDKEKPAYVVVGLDWQVDYEKFATATLAIQKGAHFIGTNPDLNIPTERGLLPG
                     AGSLITLLEVATRVKPVYIGKPNAIIMDKAVEHLGLEREELIMVGDNYLTDIRAGIDN
                     GIPTLLVTTGFTKAEEVAGLPIAPTHVVSSLAEWDFDEN"
     gene            complement(51531..52268)
                     /locus_tag="VQ543_000051"
     CDS             complement(51531..52268)
                     /locus_tag="VQ543_000051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000524807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-[acyl-carrier-protein] thioesterase"
                     /protein_id="HET2610862.1"
                     /translation="MGLTYQMKMKIPFDMADMNGHIKLPDVILLSLQVSGMQSIELGV
                     SDKAILEDYNLVWIIVEYDIEVVRLPRFAEEITIETEALSYNRLFCYRRFTIYNEAGQ
                     ELIHMMATFVLMDRDSRKVHAVEPEIVAPYQSDFDKKLIRGPKYESLEESISKDYHVR
                     FYDLDMNGHVNNSKYLDWIFEVMGADFLTHYIPKKINLKYVKEVRPGGVITSAVERTG
                     LESKHEITSDGVINAQAIITWQEIKKA"
     gene            complement(52273..53403)
                     /locus_tag="VQ543_000052"
     CDS             complement(52273..53403)
                     /locus_tag="VQ543_000052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxygen-independent coproporphyrinogen III
                     oxidase"
                     /protein_id="HET2610863.1"
                     /translation="MQKKPTSAYVHIPFCTQICYYCDFSKVFIKNQPVDSYLEHLLEE
                     FRSYDIEKLSTLYIGGGTPTALSAPQLEVLLNGLTKNLDLSVLEELTIEANPGDLDAD
                     KIAVLKNSAVNRVSLGVQTFDDKMLKKIGRSHLEKDIYENIDRLKLAGFDNISIDLIY
                     ALPGQTMEQVKENVAKAIGLDIPHMSLYSLILENHTVFMNRMRRGKLPLPKEELEAEM
                     FEYIIAELERAGFEHYEISNFSKPGFESRHNLMYWDNAEYYGIGAGASGYVNGVRYKN
                     HGPIRHYLSAVEEGNACITEDHLSQKEQMEEEMFLGLRKKSGVSMARFEEKFGQSFAG
                     LYGEIVRDLVQQGLMQIEGDHVRMTKRGLFLGDTVAERFILE"
     gene            complement(53487..53876)
                     /locus_tag="VQ543_000053"
     CDS             complement(53487..53876)
                     /locus_tag="VQ543_000053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HET2610864.1"
                     /translation="MGKLSSILLGTVSGAALALFLTSDKGKQVCSQAQDFLDDLREDP
                     EYAKEQVCEKLTEVKEQATDFVLKTKEQVESGEITVDSILAQAKSYAFQATEASKNQL
                     NNLKEQWQEKAEALDDSEEIVIDITEE"
     gene            complement(53892..54275)
                     /locus_tag="VQ543_000054"
     CDS             complement(53892..54275)
                     /locus_tag="VQ543_000054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF948 domain-containing protein"
                     /protein_id="HET2610865.1"
                     /translation="MLEVAYILVALALIVFLVYLIITVQKLGRVIDETEKTIKTLTSD
                     VDVTLHHTNELLAKVNVLADDINVKVATIDPLFSAVADLSLSVSDLNDHARVLSKKAS
                     SAGSKTLKTGASLSALRLASKFFKK"
     gene            complement(54276..55064)
                     /locus_tag="VQ543_000055"
     CDS             complement(54276..55064)
                     /locus_tag="VQ543_000055"
                     /EC_number="2.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="HET2610866.1"
                     /translation="MLDPIAIQLGPLAIRWYALCIVTGLILAVYLTMKEAPRKKIIPD
                     DILDFILVAFPLAILGARLYYVIFRFDYYSQNLGEIFAIWNGGLAIYGGLITGALVLY
                     IFADRKLINTWDFLDIAAPSVMIAQSLGRWGNFFNQEAYGATVDNLDYLPGFIRDQMY
                     IEGSYRQPTFLYESLWNLLGFALILIFRRKWKSLRRGHITAFYLIWYGFGRMVIEGMR
                     TDSLMFFGLRVSQWLSVVLIGLGIMIVIYQNRKKAPYYITEEEN"
     gene            complement(55057..55992)
                     /locus_tag="VQ543_000056"
     CDS             complement(55057..55992)
                     /locus_tag="VQ543_000056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HPr kinase/phosphorylase"
                     /protein_id="HET2610867.1"
                     /translation="MSVLVKEVIEKLRLDIVYGEPELLEKEINTADITRPGLEMTGYF
                     DYYTPERIQLLGMKEWSYLISMPSNSRYEVLKKMFLSETPAVIVARGLVVPEEMLKAA
                     RECKIAILTSRAATSRLSGELSSYLDSRLAERTSVHGVLMDIYGMGVLIQGDSGIGKS
                     ETGLELVKRGHRLVADDRVDIFAKDEITLWGEPAEILKHLIEIRGVGIIDVMSLYGAS
                     AVKDSSQVQLAVYLENYDTHKTFDRLGNNAEELEVSGVAIPRIRIPVKTGRNISVVIE
                     AAAMNYRAKEMGFDATRLFDERLTSLIARNEVQNA"
     gene            complement(56122..56298)
                     /locus_tag="VQ543_000057"
     CDS             complement(56122..56298)
                     /locus_tag="VQ543_000057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000048061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S21"
                     /protein_id="HET2610868.1"
                     /translation="MSKTVVRKNESLDDALRRFKRAVTKAGTLQETRKREFYEKPSVK
                     RKRKSEVARKRKKF"
     gene            complement(56438..57145)
                     /locus_tag="VQ543_000058"
     CDS             complement(56438..57145)
                     /locus_tag="VQ543_000058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="HET2610869.1"
                     /translation="MKVIKVENQVQGGKVAFEILKEKLANGAQTLGLATGSSPLEFYK
                     EIVESDLDFSNLTSVNLDEYVGLDGDNPQSYRYFMQENLFNQKPFKESFLPRGVKDNA
                     EAEVERYNQILADHPVDLQILGIGRNGHIGFNEPGTPFDSQTHLVELDQSTIEANARF
                     FAKIEDVPTQAISMGIKNILDAKSIILFAYGESKAEAIAGTVSGPVTENLPASSLQNH
                     PDVTIIADAEALSLLEK"
     gene            57296..58324
                     /gene="queA"
                     /locus_tag="VQ543_000059"
     CDS             57296..58324
                     /gene="queA"
                     /locus_tag="VQ543_000059"
                     /EC_number="2.4.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA preQ1(34) S-adenosylmethionine
                     ribosyltransferase-isomerase QueA"
                     /protein_id="HET2610870.1"
                     /translation="MNTADFDFHLPEELIAQTPLEKRDASKLLIVNRETGEMQDKHFH
                     SIINMLEPGDALVMNDTRVLPARLYGQKVETGGHVELLLLKNTSGDEWEVLAKPAKRL
                     KVGTRISFGDGRLSAVVTEELTHGGRIVRFEYQGIFLEVLESLGEMPLPPYIHEKLDD
                     RERYQTVYAKESGSAAAPTAGLHFTKELLAEIQAKGVHLVYLTLHVGLGTFRPVSVDN
                     LDEHEMHSEFYQLSEEAAATLRSVKENGGRVIAVGTTSIRTLETIGSKFDGQIQADSG
                     WTNIFIKPGYEWKVVDAFSTNFHLPKSTLVMLVSAFAGRELVLDAYHHAIQEHYRFFS
                     FGDSMFIY"
     gene            complement(58995..59384)
                     /locus_tag="VQ543_000060"
     CDS             complement(58995..59384)
                     /locus_tag="VQ543_000060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000240828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
                     /protein_id="HET2610871.1"
                     /translation="MVKRRIRRGTREPEKVVVPEQSSIPSYPVSVTSNQGTDVAVEPA
                     KAVAPTTDWKQENGMWYFYNTDGSMATGWVQVNGSWYYLNSNGSMKVNQWFQVGGKWY
                     YVNASGELAVNTSIDGYRVNDNGEWVR"
     gene            complement(59438..60145)
                     /locus_tag="VQ543_000061"
     CDS             complement(59438..60145)
                     /locus_tag="VQ543_000061"
                     /inference="COORDINATES: protein motif:HMM:NF019142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HET2610872.1"
                     /translation="MFRRNLNTSFVHAADGIQYVRDDTRDKEEGIEYDDADNGGIIVK
                     VATKPKVVTKKISSTRIRYEKDETKDRSENPVTIDGEDGYVTTTRTYDVNPETGHVTE
                     QVTVDRKQATDTVIKVPAKSKVEEVLVPCATKYEADNDLSAGQEQEITLGKNGKTVTT
                     ITYDVDGKSGQVTESTLSQKEDSQTRVVKKGTKPQVLVQEIPIETEYLDDPTLDKSQE
                     VEEVGEIGKLLLLQSIL"
     gene            complement(60845..61396)
                     /locus_tag="VQ543_000062"
     CDS             complement(60845..61396)
                     /locus_tag="VQ543_000062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET2610873.1"
                     /translation="MKSIGTQILQTERLILRRFVESDAEAMFQNWASSAENLTYVTWD
                     PHPDIEITRNSIRNWVASYTNLNYYKWAICLKENPEQVIGDISIVKIDEADLSCEIGY
                     VLGKAYWGNGMMTETLKAILDFCFTQAGFQKVRARYASLNPASGRVMEKAGMSYLQTI
                     VNGVERKGYLADLIYYGISREEC"
     gene            complement(61794..62618)
                     /gene="nadE"
                     /locus_tag="VQ543_000063"
     CDS             complement(61794..62618)
                     /gene="nadE"
                     /locus_tag="VQ543_000063"
                     /EC_number="6.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ammonia-dependent NAD(+) synthetase"
                     /protein_id="HET2610874.1"
                     /translation="MSLQETIIQELGVKPVIDAQEEIRRSIDFLKRYLKKHPFLKTFV
                     LGISGGQDSTLAGRLAQLAMEELRAETGDDSYKFIAVRLPYGVQADEADAQKALAFIQ
                     PDVSLVVNIKESADAMTAAVEATGSPVSDFNKGNIKARCRMIAQYALAGSHSGAVIGT
                     DHAAENITGFFTKFGDGGADILPLYRLNKRQGKQLLQKLGAEPALYEKIPTADLEEDK
                     PGLADEVALGVTYAEIDDYLEGKTISPEAQATIENWWHKGQHKRHLPITVFDDFWE"
     gene            complement(62615..64075)
                     /locus_tag="VQ543_000064"
     CDS             complement(62615..64075)
                     /locus_tag="VQ543_000064"
                     /EC_number="6.3.4.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate phosphoribosyltransferase"
                     /protein_id="HET2610875.1"
                     /translation="MYPDDSLTLHTDLYQINMMQVYFDQGIHNKKAVFEVYFRQQPFK
                     NGYAVFAGLERIVNYLEDLRFSDSDIAYLESLGYHGAFLDYLRNFKLELTVRSAQEGD
                     LVFANEPIVQVEGPLAQCQLVETALLNIVNYQTLVATKAARIRSVIEDEPLMEFGTRR
                     AQEMDAAIWGTRAAVIGGANGTSNVRAGKLFDIPVLGTHAHALVQVYGNDYEAFKAYA
                     ATHKNCVFLVDTYDTLRIGVPAAIQVARELGDQINFMGVRIDSGDIAYISKKVRQQLD
                     EAGFTEAKIYASNDLDENTILNLKMQKAKIDVWGVGTKLITAYDQPALGAVYKIVAIE
                     DETGQMRNTIKLSNNAEKVSTPGKKQVWRITSREKGKSEGDYITYDGVDISDMTEIKM
                     FHPTYTYIKKTVRNFDAVPLLVDIFKEGILVYNLPSLTDIQDYARKEFDKLWDEYKRV
                     LNPQHYPVDLARDVWQDKMDLIDKMRKEALGEGEEE"
     gene            complement(64191..64679)
                     /locus_tag="VQ543_000065"
     CDS             complement(64191..64679)
                     /locus_tag="VQ543_000065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000797183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2610876.1"
                     /translation="MKNRFYYYQLLDEREEQLINKAGSESFYICIALSLLSYIISVLA
                     PSLFNSNMLLIVIIIGTFYFFNRARYLGVTYYSRFHFTILGCFFLTLAITALLMLQNY
                     QFNIEIYQHNPLNFKYLSAWVITYVIYLPWVFIGNLGLKSYGEWAQKKFEQDMDELES
                     GE"
     gene            complement(64669..64878)
                     /locus_tag="VQ543_000066"
     CDS             complement(64669..64878)
                     /locus_tag="VQ543_000066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013670190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET2610877.1"
                     /translation="MAKNLKLKLARVERDLTQGQLAEAVGVTRQTIGLIEAGKYNPSL
                     SLCQSICRCLGKTLDQLFWEEEDEK"
     gene            complement(65268..65710)
                     /locus_tag="VQ543_000067"
                     /pseudo
     CDS             complement(65268..65710)
                     /locus_tag="VQ543_000067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000640911.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(66002..66808)
                     /locus_tag="VQ543_000068"
     CDS             complement(66002..66808)
                     /locus_tag="VQ543_000068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2610878.1"
                     /translation="MILKDINFALNKGEIVGLVGRNGVGKSTLMKILVQNNQPTSGNI
                     ISSDNVGYLIEEPKLFLSKTGLENLKYLSNLYGVDYNQERFRSLIQELDLTQSINKKV
                     KTYSLGTKQKLALLLTLVTEPDILILDEPTNGLDIESSQIVLAVLKKLALNENVGILI
                     SSHKLEDIEEICERVLFLENGLLTFQKVGKDSHNFLFEIAFSSATDRDIFITKQEFGD
                     IVQEEGLRITMSGNIQSSELFKFFNENSIKVVDFETKKETLKDIYLNRSK"
     gene            complement(67214..67942)
                     /locus_tag="VQ543_000069"
                     /pseudo
     CDS             complement(67214..67942)
                     /locus_tag="VQ543_000069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169115.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
     gene            complement(68178..68489)
                     /locus_tag="VQ543_000070"
     CDS             complement(68178..68489)
                     /locus_tag="VQ543_000070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2610879.1"
                     /translation="MIEAQGFLVDKQTRCIHYHSKLDIIALQCYVCKKYYACYRCHDS
                     LENHPFEPYPLSLIQDKPILCGVCLKLLTYKQYKESLSCPFCFSRFNPGCQNHKERYF
                     K"
     gene            complement(68504..69790)
                     /locus_tag="VQ543_000071"
     CDS             complement(68504..69790)
                     /locus_tag="VQ543_000071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HET2610880.1"
                     /translation="MTKTLKRPEVLSPAGTLEKLKVAVQYGADAVFIGGQAYGLRSRA
                     GNFTFEQMEEGVQFAAKYGAKVYVAANMVMHEGNEAGAGEWFRKLRDIGIAAVIVSDP
                     ALIMIAATEAPGLEIHLSTQASATNYETLEFWKELGLTRVVLAREVSMKELAEIRKRT
                     DVEIEAFVHGAMCISYSGRCTLSNHMSMRDANRGGCSQSCRWKYDLYDMPFGKERKSL
                     KGEILEEFSMSAVDMSMIDHIPDMIENGVDSLKIEGRMKSIHYVSTVTNCYKAAVDAY
                     LESSEKFEAIKQNLVDEMWKVAQRELATGFYYGTPSENEQLFGARRKIPEYKFVAEVV
                     SYDDATQTATIRQRNVINEGDQVEFYGPGFRHFETYIEDLHDAKGNKIDRAPNPMELL
                     TIKVPQPVQAGDMVRALKEGLINLYKEDGTSVTVRA"
     gene            70414..70596
                     /locus_tag="VQ543_000072"
     CDS             70414..70596
                     /locus_tag="VQ543_000072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001262531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ApaLI family restriction endonuclease"
                     /protein_id="HET2610881.1"
                     /translation="MANDNKSHYLIYRVLGISFEEGENIDLYQNKGRFLYKYAGSFLE
                     EAAVLSFNEKFGTENT"
     gene            70606..70971
                     /locus_tag="VQ543_000073"
     CDS             70606..70971
                     /locus_tag="VQ543_000073"
                     /inference="COORDINATES: protein motif:HMM:NF021048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ApaLI family restriction endonuclease"
                     /protein_id="HET2610882.1"
                     /translation="MPNSENTKPKTFEIDCLVGEKHAYEIKWWDATTDGDHITKEHTR
                     IKVIHNKGYIPIRLMFYYPNRTQAIKIQQTLETLYNGIGGKYYYGDSAWEHLRAVTGI
                     DLLSILTDIANKKTGVKSK"
     gene            70968..72158
                     /locus_tag="VQ543_000074"
     CDS             70968..72158
                     /locus_tag="VQ543_000074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific DNA-methyltransferase"
                     /protein_id="HET2610883.1"
                     /translation="MTVLKGDNLEILKTIESSSIDLIYMDPPFFTQKTQKLSNNKNIM
                     YSFEDTWTSIEDYKEFLSVRLEECKRVLKNSGSIFVHCDKIANHHIRLILDNIFGADM
                     FQSEIIWNYKRWSNSKKGLLNNHQNIYFYSKSKDFKFNTIFTEYSSTTNIDQILVERK
                     RNGNSKTIYKVDNNGNYILAKEKNGVPLSDVWNIPFLNPKAKERVGYPTQKPILLLEQ
                     IIKIATDKNDIVLDPFCGSGTTLVASKILNRNYMGIDLSEEAINITQQRLENVIKTSS
                     NLLNKGIEAYRTKTEEEENILKLLQAKIVQRNKGIDGFLPKHFQKKPIPIKIQKNNEC
                     LNESISLLQNAINSKKLDFGVVIKTHSDNLLFDFDTIPENIIVVDHFELTIEKWLSKS
                     QQLL"
     gene            complement(72673..73665)
                     /locus_tag="VQ543_000075"
     CDS             complement(72673..73665)
                     /locus_tag="VQ543_000075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000122906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET2610884.1"
                     /translation="MSYYDFVKDYMKVDECKNNEKYSSAGHTFCWKKENSTYAEGLYW
                     FYEGGSFIIDIHDFYIKEEVVQNSTYSMSDYVSIYSSYIVSANGEKFNPYQTITANSL
                     CTFDFDNIKDDFVFLLHENCCYLAVSIGFKKELIEKHLASININPESFYSTLLQPNQI
                     ILTKALERVAMEILNCKMDAPAADFFFKAKANEWISIVIDTYLNRKKYKIEIDDDKAL
                     EDVARFLDDHFATNVNQGTLEKISKMSGTKLKNLFKEKYCQSITEYTQRKRMNVAETL
                     LLNTELPIKEIAESVGYSSASKFSIYYKRYKGKLPSEVRNLACKHHNFKCDYCD"
     gene            73825..75579
                     /locus_tag="VQ543_000076"
     CDS             73825..75579
                     /locus_tag="VQ543_000076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2610885.1"
                     /translation="MKIYKKLFAYVQDKKYLGVLAIIFSAISAVLTVYGYYLIYKFLD
                     KLIINSNLSGAESIALKSVITLTSGAIFYFVSGMFSHILGFRLETNLRKRGIDGLEKA
                     SFRFFDLNPSGQIRKIIDDNAAQTHQVVAHMIPDSSQAIVTPILVLVLGFIVSIRVGI
                     ILLALTIIGGLILGAMMGEQEFMKIYQESLSKLSAETVEYVRGMQVVKIFKANVESFK
                     SFYKAIKDYSKYAYDYSLSCKRPYVLYQWLFFGLIAILIIPIVYFMTSLASAEVILLE
                     LIMILFLSGVLFVSFMRMMWYSMYISQGNYAVDTLEALYEDMQKDKLVHGNVNNFKNY
                     NIEFENVSFAYNDKAIIENLSFNLEEGKSYALVGSSGSGKSTVAKLISGFYNVNKGSI
                     KIGGIAISEYSDEALIKAISFVFQDSKLFKKSIYDNVALANKDATKDDVMRALKLAGC
                     DLILDKFPERENTIIGSKGVYLSGGEKQRIAIARAILKDSKIIIMDEASASIDPDNEF
                     ELQKAFKNLMKDKTVIMIAHRLSTIKDLDEIIVMDSGKIIERGSDKELMSKDTRYKSL
                     QEMFNSANEWRVSNERVL"
     gene            75563..77284
                     /locus_tag="VQ543_000077"
     CDS             75563..77284
                     /locus_tag="VQ543_000077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019214631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2610886.1"
                     /translation="MKEFYKKRFALTDGGARNLSKATLASFFVYCINMLPAILLMIFA
                     QEVLENMGKSNGFYIVFSVLTLIAMYILLSIEYDKLYNTTYQESADLRIRTAENLSKL
                     PLSYFSKHDISDISQTIMADIEGIEHAMSHSIPKVGGMVLFFPLISVMMLAGNVKMGL
                     AVIIPSILSFIFIPLSKKYQVNGQNRYYDVLRKNSESFQENIEMQMEIKAYNLSKDIK
                     DDLYKKMEDSERIHLKAEVTTILTLSISSIFSFISLAVVIFVGVNLIINKEINSLYLI
                     GYLLAAMKIKDSLDASKEGLMEIFYLSPKIERLKEIQNQDLQEGDDYSLKKFDIDLKD
                     VEFAYNKDAKVLNGVSFKAKQGEVTALVGASGCGKTTILKLISRLYDYDKGQILIDGK
                     DIKEISTESLFDKVSIVFQDVVLFNQSVMENIRIGKQDASDEEVKRAAKLANCTDFIE
                     KMDKGFDTVIGENGAELSGGERQRLSIARAFLKDAPILILDEITASLDVNNEKKIQES
                     LNNLVKDKTVVIISHRMKSIENADKIVVLQNGRVESEGKHEELLQKSKIYKNLIEKTK
                     MAEEFIY"
     gene            77295..77924
                     /locus_tag="VQ543_000078"
     CDS             77295..77924
                     /locus_tag="VQ543_000078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000368976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HET2610887.1"
                     /translation="MDNKKLKVKDLVSIGVFGVIYFAFMFGVGMMGLIPILFLIYPTV
                     LAIVAGTVVMLFMAKVQKPWALFIFGMISPLVMFAAGHTYVVVVLSLIVMIIAELIRK
                     IGNYNSFKYNMLSYAIFSTWICSSLMQMLLAKEKYMEWSLMTMGKDYVDVLEKLITYP
                     HMALIALGAFLGGILGAYIGKALLKKHFSNGLYCVGYFTPCLILWCYLN"
     gene            77825..78382
                     /locus_tag="VQ543_000079"
     CDS             77825..78382
                     /locus_tag="VQ543_000079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001851583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HET2610888.1"
                     /translation="MYRQGSIEKTLFKWIILCGILYSLPNFMVLSELNPIVKMFLSIP
                     IVIRMFILPFMAASFMIKTSDVGAIISSMDKLKISKNVSIPIAVMFRFFPSFKEEKKN
                     IKMAMRVRGINFKNPVKYLEYVSVPLLIISSNISDDIAKAAETKAIENPIAKTRYIRV
                     KIQLIDFVYVLAVAGLIVGGLIWLK"
     gene            78370..79734
                     /locus_tag="VQ543_000080"
     CDS             78370..79734
                     /locus_tag="VQ543_000080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002837029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2610889.1"
                     /translation="MVEIKNLSLDYGEEHILDDISLSIAEGECVLFTGKSGSGKSSLI
                     NSINGLAVRYDNAKTKGEIIIDGKNIKNLELYQISMLVSTVFQNPKTYFFNVNTTLEL
                     LFYLENIGLAREEMDRRLKDILEIFPIKNLLNRNIFNLSGGEKQILCIAASYIAGTKI
                     IVMDESSSNLDIKSISVLAKMLKILKEKGISIIVAEHRIYYLMDIVDRVFLIDKGKLK
                     KTYTRSEFLKLDKNELNALSLRDKELSKLKVPYLKEGGEYQIKNLSYKFTDDECLSLK
                     DISFKLGKIYGIIGSNGRGKSTLLRCLIGLEKKSKEEIYFKGEKLSKKERLKNSSLVM
                     QDVNHQLFTDEVFNELRLGVKNFDEEKAKIILKDLGLDEFIERHPMSLSGGQKQRLAI
                     ASVMCKTSPFIFFDEPSSGIDYSNMIKISELINKYKTMDKIIFIVSHDIEFLNEVADE
                     IFEL"
     gene            complement(80417..80967)
                     /locus_tag="VQ543_000081"
                     /pseudo
     CDS             complement(80417..80967)
                     /locus_tag="VQ543_000081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007897432.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus and C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(81043..81444)
                     /locus_tag="VQ543_000082"
     CDS             complement(81043..81444)
                     /locus_tag="VQ543_000082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001826718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET2610890.1"
                     /translation="MDSASIIAHTIHQKFNLKVPNYRQEEDWARMGLPITRKEIANWH
                     IKASQYYLESLYNLLREKLLEQPLLHADETSYRVLESDSQLTYYWTFLSGKSEKQGIT
                     LYHHDQCRSGSVVQEFLGDYSGYVHCDMLRQ"
     gene            complement(81452..81757)
                     /locus_tag="VQ543_000083"
     CDS             complement(81452..81757)
                     /locus_tag="VQ543_000083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family transposase zinc-finger binding
                     domain-containing protein"
                     /protein_id="HET2610891.1"
                     /translation="MFPVETEEITYKRKKSKGKRQALLAQFDSEEVHHQVEESICSDC
                     QGDLKEIGATLQRQELVFIPAQLKRIDHIQHAYKCQACSDKNPSDKIVKAPIPKAPL"
     gene            complement(81744..81938)
                     /locus_tag="VQ543_000084"
     CDS             complement(81744..81938)
                     /locus_tag="VQ543_000084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET2610892.1"
                     /translation="MKIIQQQSATIDSLTNALALLREQVAYLTQKLYGKSSEKSVCPS
                     GQLNLFEEESPSEKDGDVPS"
     gene            complement(82014..82354)
                     /gene="tnpB"
                     /locus_tag="VQ543_000085"
                     /pseudo
     CDS             complement(82014..82354)
                     /gene="tnpB"
                     /locus_tag="VQ543_000085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
     gene            complement(82335..82520)
                     /locus_tag="VQ543_000086"
     CDS             complement(82335..82520)
                     /locus_tag="VQ543_000086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001136123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2610893.1"
                     /translation="MPQPIVPVEIPQSRPFDSKKRNDILLKIRIGKLEVSFFQSLNLE
                     MVEQLLDKVLLYDNSSI"
     gene            complement(82824..84386)
                     /gene="guaA"
                     /locus_tag="VQ543_000087"
     CDS             complement(82824..84386)
                     /gene="guaA"
                     /locus_tag="VQ543_000087"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000065723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HET2610894.1"
                     /translation="MSNISTDLQDVEKIIVLDYGSQYNQLISRRIREIGVFSELKSHK
                     ISAAEVREVNPVGIILSGGPNSVYEDGSFDIDPEIFELGIPILGICYGMQLLTHKLGG
                     KVVPAGDAGNREYGQSTLTHTPSALFESTPDEQTVLMSHGDAVTEIPADFVRTGTSAD
                     CPYAAIENPDKHIYGIQFHPEVRHSVYGNDILRNFALNICKAKGDWSMDNFIDMQIKK
                     IRETVGDKRVLLGLSGGVDSSVVGVLLQKAIGDQLICIFVDHGLLRKGEADQVMDMLG
                     GKFGLNIVKADAAKRFLDKLAGVSDPEQKRKIIGNEFVYVFDDEASKLKDVKFLAQGT
                     LYTDVIESGTDTAQTIKSHHNVGGLPEDMQFELIEPLNTLYKDEVRALGTELGMPDHI
                     VWRQPFPGPGLAIRVMGEITEEKLETVRESDAILREEIAKAGLDRDIWQYFTVNTGVR
                     SVGVMGDGRTYDYTIAIRAITSIDGMTADFAKIPWEVLQKISVRIVNEVDHVNRIVYD
                     ITSKPPATVEWE"
     gene            84528..85226
                     /locus_tag="VQ543_000088"
     CDS             84528..85226
                     /locus_tag="VQ543_000088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000936186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HET2610895.1"
                     /translation="MLPAYMKIHDQIKKDIDEHRWAIGERLPSERDLAEQFAVSRMTL
                     RQAVSLLVEEGVLERRVGSGTFVSSTRVQEKMRGTTSFTEIVKSQGKVPSSQLISYKK
                     TIPNEQEVAKLGIFPTDNIIRMERVRYADQVPLVYEVASIPEKFIKDFKKEEITSHFF
                     QTLQKHGYRIGKSQQTIYARLAKEKIAHYLEVEKGHAILGLTQVSYLEDGTAFEYVKS
                     QYVGERFEFYLENN"
     gene            complement(85269..86165)
                     /locus_tag="VQ543_000089"
     CDS             complement(85269..86165)
                     /locus_tag="VQ543_000089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000071673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EamA family transporter"
                     /protein_id="HET2610896.1"
                     /translation="MSNSLKGTLLTVVAGIAWGLSGTSGQYLMAHGISALVLTNLRLL
                     IAGGILMLLAYATAKDKILVFLKDRKSLLSLLIFALIGLFLNQFAYLSAIQETNAGTA
                     TVLQYVCPVGILIYSCIKDRVAPTLGEIVSIIFAIGGTFLIATHGQLDQLSMTPAGLF
                     WGLFSALTYALYIILPIALIKKWGSSLLIGVGMVIAGLVALPFTGVLQADIPTSLDFL
                     LAFAGIILIGTVFAYTAFLKGASLIGPVKSSLLASIEPISAIFFAFLIMNEQFYPIDF
                     LGMAMILFAVTLISLKDLFLEK"
     gene            complement(86174..87109)
                     /locus_tag="VQ543_000090"
     CDS             complement(86174..87109)
                     /locus_tag="VQ543_000090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000872223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-lactamase family protein"
                     /protein_id="HET2610897.1"
                     /translation="MKWTKIIKKIEEQIEAGIYPGASFAYFKDNQWTEFYLGQSDPEH
                     GLQTEAGLVYDLASVSKVVGVGTVCTFLWEIGQLDIDRLVIDFLPESDYPDITIRQLL
                     THATDLDPFIPNRDLLTAPELKEAMFHLNRRSQPAFLYSDVHFLLLGFILERIFNQDL
                     DVILKDQVWKPWGMTETKFGPVELAVPTVRGVEAGIVHDPKARLLGRHAGSAGLFSTI
                     KDLQIFLEHYLADDFARDLNQNFSPLDDKERSLAWNLEGDWLDHTGYTGTFIMWNRQK
                     QEATIFLSNRTYEKDERAQWILDRNQVMNLIRKEE"
     gene            complement(87106..87831)
                     /locus_tag="VQ543_000091"
     CDS             complement(87106..87831)
                     /locus_tag="VQ543_000091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001102210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CppA family protein"
                     /protein_id="HET2610898.1"
                     /translation="MNVNQIVRIIPTLKANNRKLNETFYIETLGMKALLEESAFLSLG
                     DQTGLEKLVLEEAPSMRTRKVEGRKKLARLIVKVENPLEIEGILSKTDSIHRLYKGQN
                     GYAFEIFSPEDDLILIHAEDDRASLVEVGEKPEFQTDLASISLSKFEISMELHLPTDI
                     ESFLESSEIGASLDFIPAQGQDLTVDNTVTWDLSMLKFLVNELDIASLRQKFESTEYF
                     IPKSEKFFLGKDRNNVELWFEEV"
     gene            complement(87915..88550)
                     /locus_tag="VQ543_000092"
     CDS             complement(87915..88550)
                     /locus_tag="VQ543_000092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-alkyl-2-acetylglycerophosphocholine esterase"
                     /protein_id="HET2610899.1"
                     /translation="MAVQLLENWLLKEQEKIQTKYRHLNHISVVEPNILFIGDSIVEY
                     YPLQELFGTSKTIVNRGIRGYQTGLLLENLDAHLYGGAVDKIFLLIGTNDIGKDVPVN
                     EALNNLEAIIQSVARDYPLTEIKLLSILPVNEGEEYQQAVYIRSNEKIQNWNQAYQEL
                     ASAYMQVEFVPVFDCLTDQAGQLKKEYTTDGLHLSIAGYQALSKSLKDYLY"
     gene            complement(88552..89379)
                     /locus_tag="VQ543_000093"
     CDS             complement(88552..89379)
                     /locus_tag="VQ543_000093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HET2610900.1"
                     /translation="MMIKVIATDMDGTLLDARGQLDLPRLEKILDQLDQRGIRFVIAT
                     GNEIHRMRQLLSPLVDRVVLVVANGARIFENNELIQAQTWDDAIVNKALAHFKGRACQ
                     DQFVVTGMKGDFVKEGTIFTDLESFMTPEMIEKFYQRMQFVDELTSDLFGGVLKMSMV
                     VGEERLSSVLEEINALFDGRVRAVSSGYGCIDILQAGIHKAWGLEELLKRWDLKSQEI
                     MAFGDSENDVEMLEMAGIAYAMENADEKAKAVATALAPANSQGGVYQVLENWLEKGE"
     gene            complement(89401..89737)
                     /locus_tag="VQ543_000094"
                     /pseudo
     CDS             complement(89401..89737)
                     /locus_tag="VQ543_000094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398793.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="poly-gamma-glutamate biosynthesis protein"
     gene            complement(89738..90454)
                     /locus_tag="VQ543_000095"
     CDS             complement(89738..90454)
                     /locus_tag="VQ543_000095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001843873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CapA family protein"
                     /protein_id="HET2610901.1"
                     /translation="MAHGDLLYHDGLFFSAKKEDGTYDFHENFEYVTPWLKQADLAIG
                     DFEGTINKDHYLAGYLLFNAPVEVMDAIKEAGYHVLDLAHNHILDSQIEGVISMADII
                     EKAGITPIGVYTHEPRDQAPLVIKEVNAIKVALLAYSYGFNGIEQYIFQEDYNRYLSD
                     LNEDKIKAEVERAEKEADITIIMPQMGVEYRLEPTEEQKALYHKMIDWGADIIFGGHP
                     HVVEPSKTVEKDGDKKLIIY"
     gene            90977..91588
                     /locus_tag="VQ543_000096"
     CDS             90977..91588
                     /locus_tag="VQ543_000096"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HET2610902.1"
                     /translation="MSAIERITKAAHLIDMNDIIREGNPTLRAIAEEVTFPLSDQEII
                     LGEKMMQFLKHSQDPVMAEKMGLRGGVGLAAPQLDISKRIIAVLVPNIVEEGETPQEA
                     YDLEGIMYNPKIVSHSVQDAALGEGEGCLSVDRNVPGYVVRHARVTVDYFDKDGEKHR
                     IKLKGYNSIVVQHEIDHINGIMFYDRINEKDPFAVKDGLLILE"
     gene            91633..92361
                     /gene="rlmB"
                     /locus_tag="VQ543_000097"
     CDS             91633..92361
                     /gene="rlmB"
                     /locus_tag="VQ543_000097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (guanosine(2251)-2'-O)-methyltransferase RlmB"
                     /protein_id="HET2610903.1"
                     /translation="MKTNDIVYGVHAVTEALLANTGNKLYLQEDLRGKNVEKVKELAT
                     EKKVSISWTSKKSLSEMTEGAVHQGFVLRVSEFAYSELDYILAKTRQEENPLLLILDG
                     LTDPHNLGSILRTADATNVSGVIIPKHRAVGVTPVVAKTATGAIEHVPIARVTNLSQT
                     LDKLKDEGFWTFGTDMNGTPCHKWNTKGKIALIIGNEGKGISSNIKKQVDEMITIPMN
                     GHVQSLNASVAAAILMYEVFLNRL"
     gene            complement(92400..93311)
                     /gene="trxB"
                     /locus_tag="VQ543_000098"
     CDS             complement(92400..93311)
                     /gene="trxB"
                     /locus_tag="VQ543_000098"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HET2610904.1"
                     /translation="MYDTIIIGAGPAGMTAALYAARSNLKVALIEGGLPGGQMNNTSD
                     IENYPGYANISGPELAEKMFEPLENLGVEHIYGYVENVEDHGDFKKVMTDDQTYETRT
                     VIVATGSKHRPLGVPGEEELNSRGVSYCAVCDGAFFRDQDLLVVGGGDSAVEEALFLT
                     RFAKTVTIVHRRDQLRAQKVLQDRAFANEKISFIWDSVVKEIKGENRVESVVFENVKT
                     GQVTEQAFGGVFIYVGLDPLSDFVKELNIQDQAGWIVTDSHMKTAVDGIFAVGDVRLK
                     DLRQVTTAVGDGAIAGQEAYKFITEHS"
     gene            complement(93377..93601)
                     /locus_tag="VQ543_000099"
     CDS             complement(93377..93601)
                     /locus_tag="VQ543_000099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000924294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4059 family protein"
                     /protein_id="HET2610905.1"
                     /translation="MLLQLFSLYFESLILTTILVLIFLGIWIGLRAMSGVDKTARARQ
                     AHLYDMIMIGVLVVPVLSFAVMSLILVFKA"
     gene            complement(93679..94422)
                     /locus_tag="VQ543_000100"
     CDS             complement(93679..94422)
                     /locus_tag="VQ543_000100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HET2610906.1"
                     /translation="MIKISNLSKSFSGQTVLDHLNLDIQKGEVVALIGSSGAGKSTFL
                     RSLNYLETPDSGSIQIDGFSVDFSKITQEEILALRRKLSMVFQQFNLFERRTALDNVK
                     EGLVVVKKLSDQEATKIAKEELAKVGLSDRENHYPRHLSGGQKQRVALARALAMKPDV
                     LLLDEPTSALDPELVGEVEKSIADAAKSGQTMILVSHDMSFVAQVADKILLLDKGKII
                     ESGTPDEIIHTPKEERTKEFFASYKRTYI"
     gene            complement(94422..95222)
                     /locus_tag="VQ543_000101"
     CDS             complement(94422..95222)
                     /locus_tag="VQ543_000101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001103446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HET2610907.1"
                     /translation="MNVTTILASDWYQNLMQLIPDGKLFSLRSVFDGIPRIVQQLPTT
                     IMLTIGGALFGLVLALLFAIVKINRVKILYPLQAFFVSFLKGTPILVQLMLTYYGIPL
                     ALKALNQQWGTGLNINAIPAAAFAIVAFAFNEAAYASETIRAAILSVNPGEIEAARSL
                     GMTRAQVYRRVIIPNAAVVATPTLINSLIGLTKGTSLAFSAGVVEVFAQAQILGGADY
                     RYFERFISVALVYWVVNIGIESLGRFIERKMAISAPDTVQTDVKGDLR"
     gene            complement(95380..95736)
                     /locus_tag="VQ543_000102"
     CDS             complement(95380..95736)
                     /locus_tag="VQ543_000102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000889075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HET2610908.1"
                     /translation="MLEFIEYPKCSTCKKAKQELNQLGVDYKAVHIVEETPSQEVILN
                     WLETSGFELKQFFNTSGIKYRELGLKDKVGSLSNQEAAELLASDGMLLKRPILVENGT
                     VKQIGYRKSYEELGLK"
     gene            complement(95749..96261)
                     /locus_tag="VQ543_000103"
     CDS             complement(95749..96261)
                     /locus_tag="VQ543_000103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001170346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="HET2610909.1"
                     /translation="MQKKYVKILYSSPIGILSLVADDHYLYGIWVQEQKHFERGLGDE
                     TIEEVVSHPILDPVIACLDDYFKGKPQDLSNLLLAPIGTNFEKRVWDYLQGIPYGQTV
                     TYGQIAQDLQVASAQAIGGAVGRNPWSILVPCHRVLGAGKRLTGYAAGVEKKAWLLEH
                     EGVDFKDINK"
     gene            complement(96261..96755)
                     /locus_tag="VQ543_000104"
     CDS             complement(96261..96755)
                     /locus_tag="VQ543_000104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET2610910.1"
                     /translation="MEIRLAFPNEVDAIMQVMEDAKKCLADAGSDQWQNGYPNADVII
                     DDIISGQAYVALEEGELLAYAAVTKSPEEAYEAIYEGNWQAGESEYLVFHRIAVAADV
                     QGKGVAQTFLEGLIEGFDYLDFRSDTHAENKVMQHIFEKLGFKQVGKVPVDGERLAYQ
                     KLKK"
     gene            96890..97336
                     /locus_tag="VQ543_000105"
     CDS             96890..97336
                     /locus_tag="VQ543_000105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000858725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1836 domain-containing protein"
                     /protein_id="HET2610911.1"
                     /translation="MKTTFSYPKWAEIPNIDLYLDQVLLYVNQVCAPISPNKDKGLTA
                     SMVNNYVKNGYLTKPDKKKYQRQQIARLIAITTLKSVFSIQEIAQTLNTLQTQASSDQ
                     LYDAFVDYMNQGIDPANPIIQTSCQTVKLYHQTLDLIDHTQEEVIQ"
     gene            97333..97980
                     /locus_tag="VQ543_000106"
     CDS             97333..97980
                     /locus_tag="VQ543_000106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001097995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin III family protein"
                     /protein_id="HET2610912.1"
                     /translation="MNTSLKLSKQLSFGEEIANSVTHAVGAVIMLILLPISSIYSYEA
                     HGFLSSIGVSIFVISLFLMFLSSTIYHSMAYGSTHKYVLRIIDHSMIYVAIAGSYTPV
                     VLTLMNNWFGYLIIVIQWGTTIFGILYKIFAKKVNEKFSLALYLIMGWLVLAIIPAII
                     SQTTPVFWSLMVTGGLCYTVGAGFYAKKKPYFHMIWHLFILAASALQYIAIVYYM"
     gene            complement(98001..98582)
                     /gene="pdxT"
                     /locus_tag="VQ543_000107"
     CDS             complement(98001..98582)
                     /gene="pdxT"
                     /locus_tag="VQ543_000107"
                     /EC_number="3.5.1.2"
                     /EC_number="4.3.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000689933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal 5'-phosphate synthase glutaminase
                     subunit PdxT"
                     /protein_id="HET2610913.1"
                     /translation="MKIGILALQGAFAEHAKVLDQLGVESVELRNLDDFQQDQSDLSG
                     LILPGGESTTMGKLLRDQNMLLPIREAILSGLPVFGTCAGLILLAKEITSQKESHLGT
                     MDMVVERNAYGRQLGSFYTEAECKGVGKIPMTFIRGPIISSVGEGVEILATVNNQIVA
                     AQEKNMLVSSFHPELTDDVRLHQYFINMCKEKS"
     gene            complement(98583..99458)
                     /gene="pdxS"
                     /locus_tag="VQ543_000108"
     CDS             complement(98583..99458)
                     /gene="pdxS"
                     /locus_tag="VQ543_000108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012054698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal 5'-phosphate synthase lyase subunit
                     PdxS"
                     /protein_id="HET2610914.1"
                     /translation="MTENRYELNKNLAQMLKGGVIMDVQNPEQARIAEAAGAAAVMAL
                     ERIPADIRAAGGVSRMSDPKMIKEIQEAVSIPVMAKVRIGHFVEAQILEAIEIDYIDE
                     SEVLSPADDRFHVDKKEFQVPFVCGAKDLGEALRRIAEGASMIRTKGEPGTGDIVQAV
                     RHMRMMNQEIRRIQNLREDELYVAAKDLQVPVELVQYVHEHGKLPVVNFAAGGVATPA
                     DAALMMQLGAEGVFVGSGIFKSGDPVKRASAIVKAVTNFRNPQILAQISEDLGEAMVG
                     INENEIQILMAERGK"
     gene            complement(99610..100989)
                     /locus_tag="VQ543_000109"
     CDS             complement(99610..100989)
                     /locus_tag="VQ543_000109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HET2610915.1"
                     /translation="MSKIVVVGANHAGTACINTMLDNFGNENEIVVFDQNSNISFLGC
                     GMALWIGEQIDGAEGLFYSDKDKLEAKGAKVYMNSPVLSIDYDNKVVTAEVEGKEHKE
                     SYEKLIFATGSTPILPPIEGVEIVKGNREFKATLENVQFVKLYQNAEEVINKLSDKSQ
                     HLDRIAVVGGGYIGVELAEAFERLGKEVVLVDIVDTVLNGYYDKDFTQMMAKNLEDHN
                     IRLALGQTVKAIEGDGKVERLITDKESFDVDMVILAVGFRPNTALADGKIELFRNGAF
                     LVDKKQETSIPGVYAVGDCATVYDNARKDTSYIALASNAVRTGIVGAYNACGHELEGI
                     GVQGSNGISIYGLHMVSTGLTLEKAKAAGYNATETGFNDLQKPEFMKHDNHEVAIKIV
                     FDKDSREILGAQMVSHDIAISMGIHMFSLAIQEHVTIDKLALTDLFFLPHFNKPYNYI
                     TMAALTAEK"
     gene            101284..102207
                     /locus_tag="VQ543_000110"
     CDS             101284..102207
                     /locus_tag="VQ543_000110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000175414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HET2610916.1"
                     /translation="MTLRSHSERLMGTTITISLVDEQADIFLQKSFDLLKELEYRFNA
                     NSQESELMEINYQAGISPVTVHPDLFELISLGLEHSLALSSHLNISIGPLIQTWRIGF
                     SDAKVAQPQEIESVLPLINPHGIELDSSTSTVFLKQKGMKIDLGCLAKGYSADKVAQF
                     LRKEGVTSALINLGGNILTIGKNQARGDNPWQIGIQDPANPRGNHLMTIPVVNKSVVT
                     SGIYERHLTVDGQDYHHIFDSQTGYPVETELASLTIISDKSVDGEIWTTRLFGERPAS
                     ILWQVESLEGIEVILIDKEGHLSCSSGIPTL"
     gene            102267..102872
                     /locus_tag="VQ543_000111"
     CDS             102267..102872
                     /locus_tag="VQ543_000111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HET2610917.1"
                     /translation="MLKLIAIVGTNSKRSTNRQLLQYMQKHFADKAEIELVEIKTIPV
                     FNKPADKQVPAEILEIAAKIEEADGVIIGTPEYDHSIPAVLMSALAWLSYGIYPLLNK
                     PIMITGASYGTLGSSRAQLQLRQILNAPEIKANVLPDEFLLTHSLQAFNPSGDLVDLD
                     VIKKLDAIFDDFRIFVKITEKLRNAQELLRKDAEDFDWENL"
     gene            102890..>104130
                     /locus_tag="VQ543_000112"
     CDS             102890..>104130
                     /locus_tag="VQ543_000112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000673688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HET2610918.1"
                     /translation="MKFVGLVGSNYDQSYNRKLLEFIRRNFKFKFELEVLEIDEVPMF
                     NQDEKWDESFQLRFLYNKITRADGVIIATPEHNHTISASLKSVLEWLSYEVHPFENKP
                     VMIVGASYYDQGTSRAQVHLRKILDAPGVNAYTLPGNEFLLGKAKEAFDNNGNITNEG
                     TVKFLETCLDNFVKYVGVVSKLKKPKPIESEDLDCGKPIATTITEVDPDDPEWVEKVA
                     AITGAVSGDTYVKLDHGILTVNQIDMFLKAMPFELTYADDNNQFLYYNNAHQDPDTMF
                     AKRVPPQSGSRMSTVHGSLPPARMKNVEWVIGTLRNGNQEYVRTIVPGSPAGVINTHN
                     YQAMYYPDGSYAGINEIVFNFQPWLDWYLKETGQRLVGGSGPFAPAAGGHGDADATSG
                     ASDSGDAGGHGGDADATAGAS"
BASE COUNT        31774 a        22447 c        19066 g        30843 t
ORIGIN      
        1 acctacggct agcttcctag tttgctcttt gattttcatt gagtattaca gtaaacaatt
       61 tttctagcta ttgtaacaaa aaagtcactc gaaggcaact tttttcgtcc ataaactttc
      121 aaaagagaat ggcttattca gaactaaaag ccgcagcttt ttgcatttgg taatacttac
      181 cctttctatc catgagttct tgatggttac catattcaac aatatcacca tctactaaga
      241 caagaattaa atccgcatcc tgaatggttg acaaacggtg agcaatgatg aagcttgtgc
      301 ggcccttcat gagttttgca aaggcatcct gtaccagcac ttctgtccgt gtatcaatgg
      361 aagaagttgc ctcgtctaag ataagaatct ttggaatagc cagaaagact cgggatatgg
      421 tcaagagctg agcttggccg acagagagag attctccagc attttccaac ttggtatcgt
      481 atccctgtgg caactgttgg atgaaaaagt ctgcattagc tgctttggca gcagcaatta
      541 cttgctctcg actggcttca ggattgccaa aggcaatatt atcatgaatg gtcccttgtg
      601 tgagccaggt ttcttgaagc accataccaa actgctgtct caatgatact cgtgtataat
      661 cataaatgga ttgcccatcc agcaagatat ctcccgagct aatgggataa aaacgcataa
      721 ggagattgat aagagttgat tttccagcac ctgtcggacc aacgatggct accttactac
      781 cagctggaat atcgatagac aactccttaa tcaaaatttt ttcaggatgg tagccaaaag
      841 agacatgttt aaaggaaata gctcccttaa cttggtcact ggtcaagact tccttacctg
      901 tttcagccac ttcagggcta tctaagaccc catagatacg ctctacgcaa gccagagcac
      961 tttgcaactc agctagcact gaagaaatat cgttaaaggg cttggtgtat tgctgaacat
     1021 agttcaaaaa agtcactaaa cgaccgacgg tcaaggttga acccatcatg atacgataag
     1081 ctcctactcc agctaaaagg gcataaatga gtgcatttac aaagcgagtc gaaggattga
     1141 ccgttgaaga ataaaagatg gctgactgag aatagcctga gtagttgtca tgagcctcac
     1201 gcaatctttg gataaattct gtttgagcat tgaaggactg gattatagtc tgctggctaa
     1261 gcgattcttc aatcaactga gtctgaattc ccctcgtctc tgtttgcttc tggaagagat
     1321 gataggatct cttggcaata aagcgtgaaa tcaccatgga cagtggcgtc aacagcaaga
     1381 ctaagagagt catgaggaga tgaatttgga gcatggctag aatactaacc aaaatcatca
     1441 aaacaccaat gaaaaattgg ttaaaaatca tggtcaagcc agctgccaac tgttcgatat
     1501 ccgtggttac acgactgacc atctctccat tgccttgccg atccgcaaaa gcaatcggta
     1561 accgatggag tttatggatg attcgctctc gtaaatctct ggtataagag aagattagac
     1621 gattatagag gagaggattg gcccattgta ccagagtatt tcctattacc accaagagca
     1681 tctggagaaa aatctgccaa aaaactggtg atgaaccagc cactaggact tggtcaatga
     1741 cctgcccaat cagaataggt aggtaaattg ataagccaac ttgggcaata gttcctagaa
     1801 aggctaggaa aaggaggaag ggatggtttg ctaaatctac gactaaacgt ttgagcgtct
     1861 ggtttacagt ttgtcgtttc attctagtcc tcctttccat gttgggatgc attgatttca
     1921 cgatagactt gactggattt catcaagtca tcgtgcttgc caacagctag caactcacct
     1981 ttttccaaga ggagaatctg gtccgccatc tggagtgtcg aagtccgttg agaaatcaag
     2041 attaagctca tatttggcag attttcgcgg atagctttca agagcttgga ctctgtaatg
     2101 gtgtccagtg ctgaggtcgc atcatctagg atgagaaacg gagcctggcg caagactgct
     2161 cgtgcgatag acagcctttg tttttgtcca cctgagaaat ttcgccctcc tgcttcaact
     2221 agagcatcca agagtccttc cttatcactg acaaaatcct tagcttgcgc aatctccaag
     2281 gcttgccaga gttcttgatc agtcacttct tgatttaaac ctaaagtcaa gttggaacga
     2341 atagttccct taaagagttc gaccttttga ggtacatagg caatccaaga ccgccactgc
     2401 tccaaattaa gaggactacg tccattttga taaaggtcaa tgttcccctt gtctactgga
     2461 taaagtccaa gtaagagttg caccaagctt gatttaccag aaccagtccc cccaatgata
     2521 ccaaggattt gtccttgagt catatcaaag gaaatgtctc tcagagaagg ctgggccgca
     2581 tcaggatagg taaaagtcaa ttcttggact tgtaaaaccc gaccactggt aacttgcttt
     2641 tgttctaatt ctgaatggat gttttcggga gattccgcaa agacctcctc gattctcttg
     2701 gctgagatat aggactggtt gagggaattg atcagcatgg ctagcttgac caattccacc
     2761 aaaatctgta agaggtaatt gataagagca atgagagcac cttgactgag tactcctcct
     2821 tgaattgaaa tatagccttg ccagataata acgagaagag ttccattgac aatcagatag
     2881 gtcagaggtg ttaataaact agacaagaaa cctgtctttt cttgtaatct agcataaact
     2941 tggttaaggg tttgaaaaat ctgtaactct cgtttttctt gaccaaaagc acgaataacc
     3001 cgcatccctt gcaattgctg gcgcgtttcc tgaaccagtt ggtccgtttt ctttctgaga
     3061 ctactgtaga gaggattgac caatcgagat aaccctacaa tgacaatggt caaaatggca
     3121 accatgacta agaaccagaa agtcaactca gctgagattc gataagccat aaaaatggca
     3181 ccaaaaacga taatgggcgc tcgtaaaaag agacgcagga attgattgat accagtctga
     3241 atctggtagg tatccgaagt caagcgagta accaaactag aagttgtcag acggtctctg
     3301 ctgtcctttg gcaaggaaag aatatgacga taaagatcgt ttgtcaattc cttagcaaaa
     3361 cctactgctg cctttgctga gtaaaattga gctatcaagg ccactaaaac gccaattact
     3421 gcaaagataa ggagcaggcc aatctgcatc cagagatgac cttgatctcc ctgaggtaaa
     3481 gattggtcaa caatcccagc aatcaccatg ggaaccaaga gctcaaaaac agcttctaac
     3541 agcttgaaca agggggctaa aattgattcc ttgatgtagg gtttgaagta agataatagg
     3601 tgtttcataa atcccttcta ttcatattct agaaatgaag aaagtgggaa gccccactct
     3661 ctgttttatt tgtttaagta aggcaataga tagccatatc ctgctttttc catctcatcc
     3721 ttggccacaa agcgtaaaga agcagaattg atacagtaac ggaggccgcc taactcccgc
     3781 ggtccatctg tgaaaacatg acccaagtga gcactgcctg aacgagaacg aacttcaatt
     3841 cgctccattc catggctcag atccttgtaa taatgaatca actctttgga aatcggacgg
     3901 ctaaaacttg gccaaccaca acctgaagca aacttatcct tggcaaaaaa gagtggctca
     3961 cctgtcgtaa tatctacata aatcccctct tcaaaggttt ggtcataggc attggtaaat
     4021 ggagcctctg tagcagcttc ttgtgtgaca cgataagact cttcagatag actggccttc
     4081 aacacctctt gactaggctt ttcatagttt gctgcatcaa tcaatggctt atcagcatcg
     4141 gtcacatcga tatgacagta acctgaagga ttcttcctga gatagtcttg gtggtagtct
     4201 tcagccagaa tgtagtggcg taattgctcc acttctactg caatctttcg acccagcatg
     4261 cgttcctgct cctgcaccac tgtgtagata gctggcaaat ctgcttcatc ctgataataa
     4321 atcccagttc gatattggcg accacggtca ttcccttgtt gattgataga tagaggatcg
     4381 ataactcgga aataataaag taaaatctct ctgagtgaca cttccttctc atcgtaaatc
     4441 acttggaccg tttctgcatg gtctgtttcc ttgatcaact ggtaattggt cgtttcgact
     4501 tgaccattag cgtagccaac actggtttct agcactccag aaatgcgtga aaaatattcc
     4561 tctaggcccc aaaaacaacc acctgctaga taaatttctg ccatctttat ttctccttta
     4621 tcacgttttt aactaatact cttcgaaaat ctcttcaaac cacgtcagcg tcaccttacc
     4681 gtaggtatgt tactgacttc gtcagttcta tctgcaacct caaaacagtg tcttgagctg
     4741 acttcgtcag ttctatctgc aacctcaaaa cagtgttttg agcagcctgc ggctagcttc
     4801 ctagtttgct ctttgatttt cattgagtat aaacttcttt tcacaaaaag gatatgaaac
     4861 cctctggtca agagtttccc catcctatct tctattcttt attttgcttc tacacggaca
     4921 cctttggtat caactctcaa gtcatgcagt tttcctttga aaggttgctt ttccaattct
     4981 gccttaattg ttggcatctt gtcatgagaa gccagaacca taactgtcgg cccagcacca
     5041 gaaaggtagg ttgcataggc cccattttct ttggtcactt gcttaatcat cgcaaattct
     5101 cttaccaagt cctgacgata gcgctcatgg aagaggtctc cctcgattgc ttgcccagcg
     5161 gtcaccatgt ctcctgccaa caaggcagca accgctacat tggcgataga acttgcagca
     5221 acagcttcct tataagacaa ttttttaggc aagacactac ggctgtcgcg agtacgtaat
     5281 tcatagtttg gaatgtaagc tagaaaatca cactctggaa agtctgctac gatagcagag
     5341 acttgccctt caacagaact tgcaataacg agattaccat aaatggctgg agccacattg
     5401 tcaggatgcc cttcaatctt ggtcgctaac tgcaattttt catggtctga taagttgagt
     5461 tgacccagtt ggttggctag ttcaatccca gcaacgataa ccgagctgga agaacccaaa
     5521 ccgcgcgcca aagggacatc actggtcatt ttcaagcgtc ttggttgcaa gtctggtaca
     5581 atttgcaaag cgattttaag caagagatta cgctcgtcat gtggaatcca tttgccaatc
     5641 tggtgttcaa tcagccactc atctcgttct tcgcagacct caatttgaag atacttggtt
     5701 acagctacac cgaccgagtc aaaacctggc ccgatattgg cactggttgc aggtacaata
     5761 atcttcatct tattctccta gcaccttgaa ggtattcaag aggtcgaatt ctgaaacctt
     5821 cttcaattca gctgagacat tttcaagctg ggctttatta atcttgtgtg tgatgataac
     5881 gacacgcgcc ttgtcaccct ctttgccatc ttgaaggatt tgcttaaagg aaatatcttg
     5941 agcattgaag atttcagcca acttcaagac ctgacctttt gagtctagag ccaagattga
     6001 gaaatagtag tttgctttga catcttcagg atttgccaag accaagtcac ggctatattc
     6061 gttgaagtct ttgccaatag taccatcatt caaacgacga acgatacgga caatatcagc
     6121 tacaacactt gttgcagttg gtttttgacc cgcacctggt ccgtagtaca tagactcacc
     6181 aataccgata gattctacaa agacagcgtt cattacgcca ttcacactag caagtgggtg
     6241 cgctttaggt aggaaggttg gagtcacttc tgcagcaata cctgaagaag tttcctcaat
     6301 agaaccaacc aatttcacta cgtaaccaag ctcttgagct acagctacgt cttctggtgt
     6361 gatattgcgg attcccttgt gggctacatc atcaaaggca atcttcatgc caaaggcaaa
     6421 ttggctcaaa ataaccatct tgtaggctgc atcaatccca tctacgtcat tcgtcggatc
     6481 gctttctgca aatcctagac gttgtgcttc cgcaagagca tcatcgtaag accagccttc
     6541 ttccaccatc ttggtcacca tgaagttgga agttccgttg actactccaa gcacgcgcgt
     6601 aattttatca gaagccaagg aatttgctaa agtacgaaga attggaatcc caccagcaac
     6661 tgctgcttcg tagtaaagtg ctaccttgtt agcttgagcg atttctagca attctgcgcc
     6721 atggacagct aaaaggtcct tgttagcagt aacaacgtgt tttccagctt ccaaggcacg
     6781 agtgataaag gttttagcag gctcaatacg ccccatcaat tccactacga tagtaatatc
     6841 ctggtctgat aaaatatcat ccacattggt tacaaagtta aagtcattcc ctgctgcaag
     6901 caagcgattt ttttcatctt catccttgac caatacctta gcaactttga tatctgaatg
     6961 tgctgattga ttgatttttc ctccattttc ctttaggagg aaaggcacac cacttgcaac
     7021 ggtaccaaat cctagtaaag caattttaac tgtcatcttt atctcctcga aattttctaa
     7081 tatagccatt ataacagaat tttgtgaaaa ttcctattat agtaaatcac tatttcagta
     7141 taaaaagaaa aaacgaatca gacgattcgc tcttcttaaa atctgaaaat agctttccag
     7201 aaaagattag ccgatttttt gcagattgag cactgcatcg tgactcatca agacttgacc
     7261 atactcttgt aagactgagc gactgatatc actatcgtct gcaaactcgc gcatacgggc
     7321 caacagccaa gctggatatg ggcttggatg attttcaata tccactaaaa tggtcaaata
     7381 atagcgctcg ttcattttgt agagttcaga agtttccatt tcaaaagtca ctgtcttggc
     7441 aaaagctacc aagtcagcca acttagcaaa agaaaggatg tagtagatgt aaggttcttt
     7501 cttactctca gcttcttgtt cagcctgctc ttgctcttct tccttggctt caacttgctc
     7561 aagagattga atggcttcga tatcatcctt ggttttgtct gcgatgcttt tttccagggt
     7621 tttgataaat tcatctggag acatttgagc caattcttcc atatctggca aatccgataa
     7681 gtcttcaaaa tctagatttt ggtcaatctt tgacttggtc acaaagacat ctaccttatc
     7741 aggttttgga gtcacacgga agctcaacat gcctgtatcc agaaagctat caggcatctc
     7801 tagctcatcc aagatagcat aaaagaactc ttctgttttt tcttgaggaa cgagaaagtc
     7861 agcaatctcc attccacgat ccatcaaatc ctctaaagac atcgtgattt ttaaagttgt
     7921 atcactaatt tgtttcattt tcattgctag taacctcata ctttcagttc tatctattat
     7981 actagatttt tacgatttta tcaaaagaag gctcctctat acggatagat tttccctagg
     8041 gtctttctat aggagactcc aagagaaaat ttctgcagac agatagaaaa agccttcaaa
     8101 atcggctaag agccgatttt gaagacctta tacatcagaa tacttataat ttaaaggttg
     8161 ctacaccgag gatagaacga tttaagtttc tgagaatttg aagactttgc tcaaatttct
     8221 tataacgagt cactccgtac tcttcaacaa gaaggactgt atctctttcc aaaagagatg
     8281 atacatcctg taaatctaca aaatgcattc cttttaaagc ttcttgactc tgtttcaatt
     8341 tatctaggat agctttattt gagctaacga tggtcaattc ctgtccagta tttttgtatg
     8401 acaaaacatc tgctaggtta gcaattgttg taatctctgt tacaaaatca atttgatact
     8461 gagaaaaatc acctactcta ttgattgttg gattaaagag ataaactaac acatttccca
     8521 tcacaaccaa aatcacacaa accactccaa taacaactaa acgaagaatc agatttttca
     8581 catttaagcc aagcgctgtt tcaccatttg cgttcaattc tttagagttg atggtttcca
     8641 gtttttcaat tttcacattt gcataggcat gtttaaattt ctcaatcaac ccatcaattt
     8701 ttttctctaa caagtcattg gcatctttac ttgatgtcaa aattttcaca ccaacccctg
     8761 catcgtcaat catatagtag acggtcaatt ttttccacca atagtcattc gttgaatttt
     8821 tcaaggttgt ttctgtcgtg tctaattcac tggcaatttt tttcaactca ctgggttcta
     8881 catcattgaa aagataagct ccattcaaat taccatcaat caatttccca taaaaatcac
     8941 tataaccacc aatttgatga ttcaaaatcg ttttggccga ctcttttgga ggagtgattt
     9001 tatagataag ataagttgaa taacttgttg tatctttgac agtgttttta ttcctaactg
     9061 ctttaattgt aaatggtaca gcaatgagag caaataaagc gatgagagct aaaatatttg
     9121 cttttcgctt tttataaaga tttgcaaaca aatcagctac tgaataatgt tcaaacatga
     9181 tttttttctc ctttgtttag tagatactag ttttcctttg taagcatttt tgctataaat
     9241 ataatcacaa gaacaattcc ccagaattgc attgtaaata aattgaagaa actttctgaa
     9301 aagctgcttc ttggcataaa gaatagatta ttcaagatga gtagggataa agcaaatagg
     9361 attgtccttg agcgataggc tacttgcagc atggctataa ataatacgcc gagtaagaaa
     9421 ctaagcagaa agactccaat cataccatag tcggtataca actccatgat ataactactt
     9481 ccgataccat gccctttcag gtattccttg ttcaagacaa gataggatag attgtgggca
     9541 taactattac tatcaatagc tagttccaca ctattggttg tatgttcaaa ggcttttcct
     9601 ccgaaaatgg ctcccaaact cccccttgca aaataatcaa gaacaggacc aaaagtaaaa
     9661 ttacggaaat ctcggtaagg gaggctactg ttaaatagaa aacctcgagc cagaacacca
     9721 aaactagtcc cttgtttata gataaagtca agtaagatat cccagaaacc tgtatgggaa
     9781 acttggacat tatcccgtac ataattgagt actcccatcg ctaacatgag aataggagaa
     9841 cctacaaaaa tcgctaactt ttctttaaac ccaatccatt ttcctttttc agtttgctcc
     9901 cgcataaagt aataaacaaa agcaaataaa atacttaaaa taaagggatt tcgtgtccca
     9961 attgccaaat gaatagtatt agctgcaata aaggagacaa gcactgctgt ggcctgcaat
    10021 ttctttggct tggttgccag atacatacac attgcataga ccgtaaaggt agacaaaatg
    10081 taggtaaaat aaggcagttt actttcaaaa tttgcatagt aggcatagta ggaagtctgc
    10141 aaacgataca agagccgttc aaataaccga atgaaataga aaggataagt tagaagaaaa
    10201 actcctagtg atacaaagcg taaccgcttg atataaacct cttttagaga atttcctata
    10261 tttgctactt ttattttctt cctagctatg aagtaacgag ccagaatgcc tcctgtggtc
    10321 aagcccagaa tcgaaaccat gacaactata aaggcaaaac gataggctat tggatgatag
    10381 gtatccaaag caccatccct aaaataatca atggtcggtc ttgataccag aaatacaaaa
    10441 atggttaaat agaaaataaa atggattaag taatacttga tatcattcca acaagcaatt
    10501 aagctactaa ccaacaagaa caataaagta gaaagtaagc taacattatt attattaaac
    10561 agatacacaa ttccacttac tagcgtcaag gcataactga ctatggtcaa actaaataat
    10621 aatcgtttcc catcaatcac ttggtcaccc ccgttctaat gtaatttttt agatttttca
    10681 atatttttca gtaataagaa tcgatataag gaaatattta tgaatagggc caaagcacta
    10741 attcttctcc ccttacggaa aattggattc ctagaaatag caaaggcatg gccttttaaa
    10801 aaacgatgaa tctgagaata ggcttcaaac tgtttatact gatcatctag caacatctta
    10861 tccagaataa agaagtgggc ataggccaat ctgaaaaaag cgacctcttt caagtcagga
    10921 tagtttttca caacttcatt ataaaacttt tggtagatat caatataggc taaatccttc
    10981 tctgcatagg gtttggtcgt aatactatcc cctctatgga aatagtaata atagggttta
    11041 gtattaacca catacttctt ggccaacttg attaaatcaa aatggtaata ggcatcttcg
    11101 taaatcaacc ccttaggaaa ggatagggca gttgcaatct gtctcttgat tagcttattg
    11161 caaatcgtcc caggtatttt ttcacctatg aggtattcct ttagaaatgt ttgagaatca
    11221 cagacaaaat agtcatcctg attggctgac tgtgggcttt catcattagc atagacattc
    11281 atgacaccac agcttgaaac atccgcatct tcttgaacta attgctcata taagctctga
    11341 atcatttctg gatggatata atcatctgag tcaataaaaa tcagataatc cccgtgagcc
    11401 tgcttcatcc catcatttcg tgcttgcgac aatccttcgt tctttttatg aagcactgac
    11461 accctgtcat cttgttcagc gattgagtca cacaagcgac cactttcatc tgttgcacca
    11521 tcatcaacaa gaataatttc cagattttga tagatctgct tctgaatgga agctatcgat
    11581 ttttctaggt actgcgccac attatagact ggcacaatca cactaattaa tgcagtttcc
    11641 atgctactcc tctaatagtt tttctacttg ttcgatttgt tttgtaattg taaattgttg
    11701 aatgaattgg ctagcctcat cgacatcaaa gtttgaggca gaagtcatgt aattagtaat
    11761 cgcctgagct gcctcttgat tgctctcaat gatttgtcca aatcgtcctt cttgggataa
    11821 ttcctcagcc cctccaacgt ccgtagagat aaaagggagt cccagactca aggcctccac
    11881 atacactcca ggaaaacctt cttgtttaga catagacaag agaactttcg tctgagataa
    11941 atactgataa ggattttttt gataaccaag gaaatgtaca tagtcctcaa tcccatactc
    12001 tttgactcgt tttttcagtt cctcttccat atcaccagcc ccgataaaat agagatgata
    12061 gttttttccc tcttggtgta ataatcgtat cacttccact acacggtcag aacccttatt
    12121 ttcctcaatc cgtccgatag tacagatact ttgaggagca atctcgatat cgatcttctc
    12181 ttgagatttt tctagaatag tctgaaaatc atatccattg tagattatct gtaatttaga
    12241 agcataatct ggataaactt ccttgataga attgctggtc ttttttgaaa tccctacaat
    12301 tgtattcgca gcatccaact ggcttctatg tgattctctt ttagagctat ccttaagaag
    12361 ttcttcaata cttccatgaa tccaagatat cttcttgact tctcttcttt tagagaacaa
    12421 cagtggtgga ttcataatgg taaaagaaac ttcaacatca taatcatctt ttacaagcaa
    12481 acgacgagtc agtcttggaa aataaattct cattctccac aaaaaagctc gtaaccatct
    12541 ggtttggcga taatcttgaa gggattttaa aatgcgtaca tgctttggaa cagattcata
    12601 tcccttgtca aagtgctcca tttcaagaat atcaatatca tacttttcta gatccagatt
    12661 tgaaacaatg gttgatagaa tcttctctgc accacctcca agagaaaaag accacataaa
    12721 aaataagatt tttttcttag ccaccatatt ctcccttgta ttctgtataa gacttatcca
    12781 tatcagcgat gacagcatca tgatgcggta cctgcttgtc tgctggtgga ggcgtcatat
    12841 aatccccaaa agcagttctg agatagacat catagccgat tggaataggc atctctgttc
    12901 cttcaaatgg caagaaaaga ttgtcttcaa aagatgtgat tgggtacttg tttctcatgt
    12961 agccaggacc tgagcataat tctgtaatgc catcacaatc agccaaatca tacttagtca
    13021 tttctttctc agcttttttc cagatgcgat aacggagaga ttttggagtc aaacccagta
    13081 aaatgcgact tccccatttc atgagagcac catgcttttc tggaatagtt tgcgcacaaa
    13141 agagtgaata aatcaaggcc caacgaacct gttttttccg ctcagctgga tttttcggat
    13201 aataatccaa aggcaaaaca tccaaggtca gaccatgtgg caaatctaaa tcctgctgat
    13261 aaggcttgat acaggtggtt tccttgtcac gaatggtaat aaaaagatta cgatcaacaa
    13321 aatccttgtg actctttgac aagaaataac gttcatctgc ataacgaggc cataattctg
    13381 ctaatttctc ataatcttta cgaggcataa aaaagtctag gtcgtcgtcc caaggaataa
    13441 atcccttgtt tcgaagggca ccaatagcgc ctccgccaca gagataacag agcaaatcat
    13501 gttctttaca aaaggccaca aaatattcag ccatctccag actacgagcc tgaattgctt
    13561 ttaaatcagt catattgttc attattcttt ctatcgtatc gtttcattat accacaaaca
    13621 aggggtgaaa atctattgca gactgtaaaa aatcaaagcc tgactgctat ccaaatagct
    13681 atcaaacttt gatttttctg tcttatactc ttcgaaaatc tcttcaaacc acgtcagctt
    13741 caccttgccg taggtatagg taactgactt cgtcagtctt atctacaacc tcaaaactgt
    13801 gtttttagca gcctgcggct agcttcctag tttgcacttt aattttcatt gagtattatc
    13861 ttatctcaag cccatttgag cgagcttggt ttgatatttg ttttgatcaa ccagcaagcc
    13921 caagcctcca taaacatcat aggcatctac ccagtcaccc agttctggaa tcgtcaattt
    13981 ttcaatacca ttttttgctc catccaaaac agataaaccg tttgttagga ggaaagtata
    14041 gggtacgttg gttgaggtca tagcaaaaac ctttccaaga gcttcagaac cagtgaaaag
    14101 tttagtggga tctttaattt gctctaaaat tgctgttaaa acttgttgct gtctttttgt
    14161 acggccgtaa tccgcctcat catcatcacg gaaacgagca taattgagca gggtcgagcc
    14221 attcatctgc tgttttccga ctttaatggt ttgggttgga gactcagtct cggtagcgta
    14281 taaatcatct ccgactgtag cttctgttag gggacgccca ttcaatgttg aaaattgagc
    14341 atcaatcgtc accccatcag ggaaaagcgt gtcaatcgct gtggcaaagg cctggaaatc
    14401 aaccaaggcg tagtacttaa tgtccaagtc aaaattatct ttcaagactt ggcgaaccat
    14461 ttctgcccct ttttgcccct cttgttctcc taactcgtag gctacgttta acttgttatc
    14521 tgtctgtttt ctaccattaa tcacttgact ataaccatct atatagacca aattatcacg
    14581 catgaaactg actagcttca ttttcttatc tgagcccccg acatttaata ccataataga
    14641 gtcagttcgt gtctcaacac tgttctggcc gattcgacca tcagtaccca tgattaaaat
    14701 attaactcca tctctagtgt cctgaccatt aaagacttct acttgagctg cccgggcatc
    14761 agcagttttc tttgcgctag catcttggta accacgcaaa aacatgaata ccatggccaa
    14821 agccacacag accaaaagtg aaaaaatcac cataaaaatt cgtttaagac ggagcttccg
    14881 tcttttcttt tttggaggga aagagagtgc ttgtgatttg gattgtgagc gactccggtt
    14941 cgcatagctt ggtaagtcaa cctgctcttc tctttcttgt tccaagctag agctactatt
    15001 tcccctagca agagttagct tttcttgcaa ataggcaaac tcattttttt ctctctcatt
    15061 gagatagtga atatttttta gcaaataatc ataacgcaac tgctcatgat gacttaaggg
    15121 attttcttta ctcatcttct ctcctttcca tggtctgata ttggataaat aggataggca
    15181 cccagaattt tatactggat tccaatcgct tctaattctt tttgggcaaa gtggaccaag
    15241 tccttatcga tataatccac atcgataatg aaaaagtatt cacccagtgc tgtcttgagt
    15301 ggacgacttt caatttttgt caagtcaatt cctcgccaag caaaggtcga cagggcctta
    15361 taaagtgcac ctggaaggtt gtcaggtaat gtcaaggcca aactcatctt ttcagtttgt
    15421 gcttgcaagg gaatactagg cttttcagct cctagaaccc agaaacgtgt gaaattggct
    15481 tccatttcct gaatatcctc ggcaatcagt tccaatccat attcttcagc agaacttcta
    15541 ggtgcaactg ctgcaaaggg ctggtctgga tgttcggaaa taaaacgggc cgcataagct
    15601 gtactagctg ttacctcgat ttgagcctct ggatattgtt catcgatgaa tttctttcct
    15661 tgagccaagg cctgtggatg tgaaaaaatc ttttcaatct tagtatggcc tggaaccacc
    15721 atcaactgct gatgaatagg ctgaacgatt tctgctactg cttggatgtg agcctgatga
    15781 aaaagatagt ccaaggtttc atgaacacta ccctcaatag aattttcaac tggcaccaca
    15841 gaatagtcca ctaatccttg ctcataagcc ttgatgacat ctgtaatgtt ggcaaaagcc
    15901 tgcaattcct catgaggaaa agctgtctgc acaacgtggt gtgaaaatga tcccttggga
    15961 cctagataag ctattttcat cttagttcct ctataatttc ctctgggctt agcttggtca
    16021 catccaaaac ccgactagcc acttcctcat accaagcctg tctttcttga aaaatagcta
    16081 ctagttcttc cttgctatta tttagaaaaa gcggtcgctg attgtcctta tcagctgcga
    16141 tacgtaggta gagggtttca aaatctgctt tcaggtagat gttatctgta ttagtcttga
    16201 gtaagtcacg atttctctga gaaataacca ctcctcctcc agttgacacg acttggtctg
    16261 tttgtagtaa atcagctagg acttctgatt ctacatgacg aaaggctgct tctccctttt
    16321 cagcgaaaaa attcgcaatg gacataccta ggcgcttctc aatcagagca tccatatcaa
    16381 ggtaattagg gtccaagcct cttgcaatag tcgattttcc agcccccata aaccctaata
    16441 acaccttagc catgaatcaa gctctccaaa tcatcaaaga aactaggata gctggtattg
    16501 atggcttctg cacggtcaag ctccacctct ccatctgcaa ccaagagggc tgcgatagct
    16561 gtcatcatgc cgatacggtg gtcaccaaac gtattgactc tagcaccgtg aagagctgat
    16621 ttccctttga taatcatccc atctgccgta ggagtaatat ctgctcccat actatttaag
    16681 gcgtctgcca caacctgaat acggtctgtt tccttgacct tgagctcctc agcatccttg
    16741 ataactgtta caccttgggc ttgagtcgca agcagggcaa taatgggcaa ttcatcaatc
    16801 aatcgtggaa tcaaagcgcc accaatctct gttcctttca agtcagaaga ctcaacaatc
    16861 aaggtagcag atttagcgac tggatcgatt tcagttattt ccaattttcc acccatggca
    16921 cgaatgacat caataatacc ggtgcgagtt tcgttgatcc ccacattctg cagcactaga
    16981 cgagaatttg gagcaatcaa acctgcgact aaccaaaagg ctgcactgga aatatctcct
    17041 ggtacgacca ccttctgtcc tgtcaatttt tgtggcccct ggactgtgat tttcttacca
    17101 tccacactta aatgaccacc aaattgttgc aacatatctt cagtatgatt acgggtgtac
    17161 tctttttcga taataactga ctccccctta gcttgtaagg ctgcaaacat caaggctgac
    17221 ttgacttggg cagaggcaat tggcaactca taatgaatag gtcttaggtt tttcgtccct
    17281 tttaagcgaa ggggaggcaa gtctcgttca gtttgccctg aaatgctgac gcccattttt
    17341 ttcagtggaa gggtcacacg gtccatagga cgtttggaaa gactatcatc tccaaacatc
    17401 tctacttcga aatctgcacc agcaaggaca cctgaaatca ggcgaatcga ggtgccagaa
    17461 tttcccatat taagggcatt ttgtggcgct tttaagccag ccatgcctac accttgaatg
    17521 gtaataaccc catctttatc ctcaatttca acaccaaggt cacgaaaaac ctgcatggtc
    17581 gaaagaacgt cttcacctcg cagaatatca taaaccttgg tctcaccctc agccaaactt
    17641 ccaaagataa tggaacggtg gctgatagac ttgtcacctg ggacgcggat actaccatgt
    17701 aaatggcgaa tgtttgtttt tagtttcata ctggacctca tacttgcaat acttttacct
    17761 attttatcat aaaaagtcag aaattcctta aaaattcctg actttaggat cgttcttttc
    17821 ttatttcagc aattctgaaa ctggttcaaa aacaattttt tcaatgtcag aaaggtaaat
    17881 ggccaattgt tgttgcttgg taaagaattc tgacaagagg ctatttcctt gaatctgttt
    17941 accaaagcct tccatcttag cttggaagga cgcatctggc atttgacctg tctgtgctag
    18001 tttttgaatt tcctcttgaa aggcaagata ttctgtaaag attttgcttg cctcagcatc
    18061 tgctgcaatc gcatctttag ctgctttaac agccttgtat tctggtaatc cgcgtagacc
    18121 gcgactgagt tcgtttgcac tatcgtaaat atttgacatg ttcttctcct tatttgatga
    18181 cgactgtata gtcggtattt tctgttatga gatgctcagc tctttccaag tcttgagcat
    18241 ttttaaatga aatttgtagg attccgtgaa tatcctcacg attttcctcg ttgatgtgga
    18301 tgttaaccaa ggaagttcca cgtagcagtt ccaaaatccg caggatgaca tcttcttcat
    18361 caggaacgtc aacatagagg tcgtaagagc tatccacacc accacgctta tggatttcca
    18421 tggtctggcg ttgttcacgc gcttggttaa aaaagttcca aatttgctct tcatctccct
    18481 tactaatggc ctgaccaatc acttccaaac gttccttgaa atcctcaatt ctatccagaa
    18541 tggtctcgct attggacaag agaatggagg tccacattcc tggctcgctt tccgcaattc
    18601 gggtcatatc tcgaaaacca cctgccgcaa agcgccttgc catctcatgc tcttgagcat
    18661 agaccgcagt ctgctccatg agactagaag ccaaaatatg aggaaaatgg ctaatctgag
    18721 aagtgacacg atcatgctcc ttggcatcaa tctcgataaa acgagcatga agacctgaaa
    18781 gcagatcctt catttcctta agcgtgtcct gacttgtcag gcttgaaggt gtaaagatat
    18841 aataggcatt ttcaaaaaga ttgacatctg ccgaagcagc ccctgtcttg tgactaccag
    18901 ccatgggatg ggccccgaca aagcgaacag acttgccagc caaatactgc tccgccgcat
    18961 ccacaatggt tgacttggtc gaaccagcat ctgaaataat aacgccttct cgcaaatcca
    19021 aattggccaa ctccttaatg aaagcaatag tttgtttgat tggcaagctg aggataatga
    19081 catctgccaa aggagcaaaa ctagcaaaat catccgttgc acggtcaatc ataccttctt
    19141 tcaaggcgat atctctcgaa gcttgactac gattataacc taaaatttca taatctggat
    19201 gatcgcgttt gataccaagt gccatagagg ctccaatcaa cccaagacct gcgatataga
    19261 ttgtttttgc cataggaact ccttaatagt tctttgtata gtctcggtgt ttggctaccg
    19321 cttcttttag ttcctcaaga ttatctgatg agaatttttc gaggatttct tgcgccagaa
    19381 ccgttgctac aactgcttcc atgaccattc ctgcagctgg aagagcagtc ggatcacttc
    19441 tctccacggt tgccttgtaa ggttcgtggg tttcgatatc cacactcata agaggtttat
    19501 aaagagtagg aatgggtttc atgaccccac gaacaacgat gggttgccca ttagtcatac
    19561 caccttcaaa accacctaga ttattggtac ggcgagtata accgtcttct ttagaccaga
    19621 gaatttcatc cataacttgg ctgcctttac gataaccagc ctcaaagcca agaccaaatt
    19681 ccaccccttt aaaggcattg atagagacaa cagcttgagc caatcttgca tccaattttc
    19741 tatcccattg gacataggaa ccaagaccaa ctggaacgcc tccgacgact gtctccacaa
    19801 ccccaccgat ggtatcacca tcacgtttga tttggtcaat atagtccttg atttcctgtt
    19861 ctcgttcttg gttgacaata gaaacttcag actgggcagc tctttgctta atttcagcga
    19921 ctgtcagatt ttcaggaaca tctatttcct taccaccaaa gaccacgaca tggttggcaa
    19981 tctccatatc cagctcagcc aagaggcgtt tggctactgc accaactgcc acccgcatgg
    20041 tggtttcacg agctgatgaa cgctccaaag aatttcgcaa atcatcaaaa cggtacttaa
    20101 tccccccaac caaatcggca tgacctgggc gaggatgagt aattttccgc ttgcttttaa
    20161 ggcggtcttc aatgtcctcc gcagacatga tgtccagcca tttctggtgg tccttattga
    20221 tgacatccat agtaataggc gcccctgtcg tcttcccgtg gcgaacaccc gaagtaaaga
    20281 caacctggtc actctcaatc ttcatacgac caccacgacc gtagccaccc tgacggcgtc
    20341 taagatcctc attgatatcc tcagctgtca atggaagtcc agctggaatt ccctcaataa
    20401 tagctgttag acgggggccg tgtgattctc ctgcagttaa atatctcata cactctcctt
    20461 attttaccaa gtagtctttc atctcttcca gagaaactgg gtgaatggtc gctgaaccaa
    20521 gctctggcac caagaccaat ttcaaggtgt taccacgcgc tttcttgtca tgagtaagag
    20581 cctgataaag cttgtcaact ttccaatttt catagtcaac aggcaagccg aatttctgac
    20641 acatctctgt gatagattgg gtaatgccag ctggcatgag gcctttttcc tcagcaacct
    20701 tggaaatctg taccattccc atggcaacag cctctccatg catgaccttg ccataaccgg
    20761 cagtcgcttc gatggcatgg ccaatagtgt ggccaaaatt gaggtaaaga cgaataccat
    20821 tgtccaactc atcttcaacc accatcttgc gcttcacctg acaagaatgt tcaatcaagg
    20881 tctctgcatg ttccaaaata ctctcaacag aaccattcag tcccgtcaag agagcccaca
    20941 gttctggatc ctcaatcaag ccatacttga taacttcacc catcccttca atcaactctc
    21001 tttttccgag ggtttcaaga acaagtggat caatcagaac cccatctggt tgggcaaagg
    21061 tccccaccat atttttagca aatggtgtgt taacgcctgt ctttccaccg atagaagaat
    21121 caacctgagc tgtcaaacta gtcggaatct gaacaaagtg aataccccgc atataggtag
    21181 aggctacaaa gccagccagg tccccaacaa cgccaccacc aagagcaacg attccatcgc
    21241 tacgagtcag accttgcttg actagaaatt catagacttt ctgaacagta gttaaattct
    21301 ttctttcttc accttctaag aaatcaaaaa cagctacctg aaaaccagca tcttctaggc
    21361 tgagcttgac cttctctgca tagagagagg ctacatggtt atctgtcaca atgactacct
    21421 tttgcggttg ccagagttct cgcaaccact gaccagcctg ggccatacaa cctttttcaa
    21481 tctgaatatc ataaggatga tgaggaatat cgattctgat tttcatagga gagtctccct
    21541 ttctttattg atatttttct gttaaagact gccaaatctc ttctgtcggc attttcttgc
    21601 ctgtccacag ttgaaaagct tctgcagctt gatagagcaa cattcccaga ccattgactg
    21661 ctggattgcc ctgacttcta gcccatttca aaaacggtgt ttcaaagggt tggtatatga
    21721 tatctgcaac taagagagtt tctggtaaga ctatgttttc aggaacagga gaggattggc
    21781 catccatgcc cacactggtg gcattaacta gcaaatccga ctcggcaatc cttgcttgca
    21841 gttcagaaac atattctaaa gcacacaaat ccactttaaa gcctgtctgc tcctgtaact
    21901 tgtctaggta aggtcttgtt ttttccatag aaacggaacg aacaaagacc gaaatctgac
    21961 tgacgccatc caaaatagcc tgtgccaaga ttgatttagc cgcaccacct gcacccagca
    22021 gggtcatctt tttacctgaa attgtaaaag aaggcaagca cttaaaaaat cccttgccat
    22081 ctgtattata tccaattaaa ttgccattct cattgacaac cgtattaacc gcaccaatca
    22141 agcgcgcttc atcgctcagc tcatccaaat aaggaatcac ctgctcctta tagggcatgg
    22201 acagattgat gccaaacatc tggtagcgac gaatattggc cactgtttct accaagtcac
    22261 tcgcttcaat ctcccaagcc acataagcac cgttggtagc tgtcgcctca aaggctctat
    22321 tgtggatgaa gggagaaata gaatgcttaa taggattggc aacaactgca gctaaacgtg
    22381 tatagccatc aagcttcatc caaaatctcc ctgatttttt tcatgctagc tagagaaatc
    22441 tgcccagggg cactaacctc atccagactg gcaaaagacc aactcgaacc agtcacatcc
    22501 gcagtgatac gagagacctt gcccacctta cccatagaaa tggtcacata ttcctgttca
    22561 ggattgagcg ttttaaagcc tcgtgtatag ttcatcaagt ctaagacatc ctgctccgtg
    22621 tgagccatca ccgcaacctt aacaagtttt ggatttagga tcgtcaactc tgacaagatt
    22681 tccatcatgt tctcaggtgt ttcttggaaa ttatggtaac tcaaaacaag atttgggaag
    22741 tccagcattt cctcaaaaac atccttgtag ctatagtact caaaatcaat atagtctggt
    22801 tgatagagtt gcgcaacttc cttgattaga tggatatact cttctggaga aaggtcgatt
    22861 tctccacctt cggagcgagt tcgtagcgtg aaaaccaact cacggcctgc gaatttttca
    22921 aaaatggctg gagctacctg caaaatcgct tctttaggca gatagtcggc acgccattca
    22981 atgatgtcgg catccaggta cctcgtggca tccagagcct gagcctcctc taaacttctt
    23041 ggcattactg aaacgattaa tttcatttac taaccttcat actaatcacc ttgaggtaat
    23101 tactactttc atctttttta ttataggcaa aatctgctgg aagaccatat ttgtttaaaa
    23161 tctggtaact tcttcctgca aagcctttat caatttgttc tgtaaatttc tgacgggaaa
    23221 cattggcagc attggtactg gcaatgataa tccctcccgg atttaaaatc tcaagactct
    23281 gggaaatcaa cttgtgataa tccttggcca cagagaaagt ttgtttttta ttccgagcaa
    23341 agctaggcgg atctaggaca atcacatcgt aggtcaagtt tttgcgtttg gcatatttga
    23401 aatactcaaa gacatccatg actataaaac gacgctcgtc tgtgctgagc ccatttgcct
    23461 gaaaatgcgc ttgagacaat tctcgtgaac gtttggctag atcaacagaa gttgtctggc
    23521 tagctcctcc catggccgca gctactgaaa aagccgctgt gtaggaaaac atattgagca
    23581 aggatttacc catagccaag ccgtcaacta aactaccgcg aacctcatgc tggtctagga
    23641 aaattcctgt catcaagcca tcattcataa agacttgata caggacacca ttttctaaaa
    23701 cagtgaaaaa gtcaggtgct tcttgaccat aaacatgggc agattcatag tccaaaccct
    23761 taaagcggat tttctcataa gcccctaaaa cctcagggaa aacctgtcta aaggcttctg
    23821 atatagtctg acgaatctga taaacataag agttatacca agaaaagacg gcgtagtcgc
    23881 cataaaggtc cactgtcaga cccccaaagc catctccctc ttgattaaag agacgaaagg
    23941 cagttgtcaa atcatcttga tagtaggcgt ttctcttttc tttggctttt ctaaacaacg
    24001 tttcaaagaa agcttgattg aaggccacct tgtctttgct gacaaaccag cccaagccct
    24061 tgttttgctg agaaaggtag gcagtcccaa gaaagtttcc ttcctgaccc tgcacctcta
    24121 cttcctgatc cttaagattg acattctcaa gatcactggc ttctagtaaa actagcccct
    24181 tagcaagctt cttttcaacc cttttgctga ctcttattct attcataact accattatat
    24241 caaactttta gacaattctc aaaaaagaaa ctacccttgc ttttttactc ttcttttaaa
    24301 aaatggtata ctagacttcc tgcaaaacta ggaagtaaat gtgtaagaat cacaataaaa
    24361 aatgctcttc cgtcttggag gagcatttct ttttatcaac gaaaatcaaa taacaaacta
    24421 tgaaactagc ctcaggttaa ctgtgagatt ataggtagag aggttgaatc agcaatatgt
    24481 gtctgtcaaa tttagtgaca aaggtagtag aagaaagatg aagaaataaa tctgcttcag
    24541 tagatatctg gaaaatttga ttttatagaa aagccttttg ttacaaactc aatatactat
    24601 caataaataa tattatagaa gcaacaataa ttaaaatttc acctatttgc atcattctat
    24661 ttcgaactct aaatatatgt tctatcaaaa atacttggat cacacacatt ataggaatta
    24721 acgtttttga aattgaaaaa tatcccaata aataaactat aaacaacaat aatagaacta
    24781 tattatattt cttattcaaa acattcctcc ctatattttt gattaccaat cttaatcatt
    24841 tacaactaca ttctaacaaa ctataaaagc gtttgtcgaa ttgaatttat caagcaagca
    24901 accaactatc tcatcttttt tctatttctg ccaatatgcg tgacaggtaa taatgatagc
    24961 caaaaatagc aagagcaagc aagacgataa gagctcctac tcccaagttg atggcaagga
    25021 taggggagag agactgaacc aagaatatgc tcccaattac aagggccatc aggattgcac
    25081 tataaataaa caataaaact atggcgacta tgccatttga acgattcacc aggtccgtaa
    25141 tgctactcca attggttgac agatttttaa cgtccttaaa gtaatggtgg caagaaagga
    25201 tgacactggc aatgatccag actacaagaa ggtaaatcat cgaaaggatg gacaagccta
    25261 gatatagaga aagaccgagc aaagtcagaa ctggtaaaaa ggactgaaca gcaaagataa
    25321 tccaaaattt cactttcaca taacgagcaa agtcaaaggg taaactcttc agaaaatcaa
    25381 cattttccct ctccaaggac aaggcaattg aatgcaggct ggtgatattg ttattgacaa
    25441 ctgctataaa cactcctaca aaaaacaagg gtaaccagta tggaggatga atgtctggaa
    25501 ctatctgaga atctcggatt ttggaaatca gactgatcat catgagataa ggaaggaaag
    25561 cacttgtaaa aagcactgta atcacaccag tcccctatcc caagagggtg aggtggtagc
    25621 gtaaaaccat acggaaaaag ccctttttag tagttgaaat cctctccttg ctgcgacgtt
    25681 cttttttgac cttctcctca ctgttaagca ggatcacgtc ataaaaacga ggaaggacct
    25741 tctttttggt cagataaagc aggaagagag ttagtcctat ccaagcgagc agacccacta
    25801 aggcttctgt cgaaaaaggc tccactgcta ttttgtaaaa gatatgaaga ggataaagga
    25861 gaaatggaat gtctctaact ttgtcaacaa tacttccaaa agtcgactga agaaagaaga
    25921 taaatattaa aggtatgaga actcctatcc caatcatcac attcgaaaaa atagactgat
    25981 actttctgaa gaccctagtc tgagccaaga aatgtactgc cactaccgtc actaaagtaa
    26041 cagagacaaa taataaggtc aaggacagta gcatcaaagg caaacccagc caaagagaag
    26101 gagctagact aatatagagg gctagaaaat aagctaggat tggtacaatt ccagttagag
    26161 ctggcaagag gacagacaga cctttggcca ttataatctc tgattcttta aaggcatagg
    26221 gcctatagga ggccaggtcc ttactctcat aaaagacatt gtaaaaggca gtgaaagaag
    26281 ttgaaaaggc cagcaccagt aaaatagcaa ccatcgagct aaaataaata ggtatttcct
    26341 caaaaggaaa atgaatggct atattactaa aacagatgag catcaagaga ctggaaaaaa
    26401 tgtaagaact taggactcta gcagaaacat ttactttttt cccaggattc ttagcctgct
    26461 tctttcgtag attagccaga ttagcttctt gagatgaata gaggatattg atatcaacta
    26521 attttttaat gaccttgaga cgcatccgca acctcctctt ttctaccagc aagactaagg
    26581 tagatacttt ccaaaaactg gtctgggtgg tctttcctca agttctctac actaccacaa
    26641 tagatcaaat gccccttttt caaaatagca atccgatcac agacttgctc ggctacctca
    26701 aggacatgag ttgaaaacaa gaccgtcttg cctttttgtg catgttcctt catcatttgc
    26761 ttcaaatcaa aggcggcctg gggatccaaa ccagtcaagg gttcgtccaa aacccaaata
    26821 tcaggagcag acaagagtgc cccaatgaca aagactttct gacgcattcc gtgagaaaga
    26881 gtttcaataa cctgatagcg gttttcagca aaatcaaaaa cgttcaatag cctagctaga
    26941 ctagtctcca agtcagagct agtcagatca taggatgaag cgatcaattc ccaaaattca
    27001 ttggccgtta agcgtaaaaa taagtcaggc gagtctgcta cgtagccaat ctttcgtttg
    27061 atcgccaagc gattttccga taactcctga ccgtctacca aaatacgacc actgctgggt
    27121 gaaatgatac tgactaggga ttttatggtg gtcgattttc cagccccatt atgaccaatc
    27181 aagcccataa tctctccatt ttcaatctgc aaattgagat tactcaaggc ctctttatca
    27241 ccatacaact tactaacatt ttgaaattca atcatgggac aactcctatc tttatctgta
    27301 ttatacatcg ctatactagc actttgatac aaaaaaatca atactttatt ttaagtagtt
    27361 aaaatagttt ccttctatct tacgcaaacg tttgcgccga gagatacttt atgatagaat
    27421 aaagaacaag attgacaagt aagaggaaac atcatgcaaa atcaaacact catgcaatac
    27481 tttgaatggt atctgcccca cgacggtcaa cactggacgc gtctggctga aaatgctcca
    27541 cacctagctc atctggggat cagtcacgtc tggatgccac cagccttcaa ggcaaccaac
    27601 gaaaaagatg tcggctatgg ggtctatgac ttatttgact taggagagtt caaccaaaaa
    27661 gggactgtcc gcaccaagta tggtttcaaa gaagactatc ttcaagccat tcaagccctt
    27721 aaagaacagg gaattcaacc tatggccgat gtagttctca accacaaggc tgctgccgat
    27781 aacagggaag cctttcaggt tatcgaagtt gatcctgtag accgtacagt tgaacttgga
    27841 gaacccttca ccatcaatgg ctggactagt tttaccttcg atggtcgcca agatacctat
    27901 aatggcttcc actggcattg gtaccacttc accggtacag actacgatgc caaacgcagt
    27961 aaatctggga tttatctgat ccaaggggac aacaagggct gggctaacga ggaattggtc
    28021 gataacgaaa acggaaacta cgactacctc atgtatgccg acctagactt taaacatcct
    28081 gaagtcatcc aaaacatcta tgactgggct gattggttca tggaaacgac tggtgtagct
    28141 ggtttccgtt tggatgccgt taagcatatt gactctttct ttatgcgcaa cttcatccgc
    28201 gatatgaagg aaaaatacgg tgacgatttc tatgtttttg gtgaattttg gaacccagac
    28261 aaggaagcca atctggacta tctcgaaaaa acggaagaac actttgacct tgtcgatgtt
    28321 cgtctccacc agaatctctt tgaagccagt caagctggcg caaactatga ccttcgtggc
    28381 attttcacag atagcctggt tgaactcaag cctgacaagg ctgtgacttt tgtcgacaac
    28441 cacgataccc aacgaggaca agcccttgag tctaccgttg aagaatggtt caagccagca
    28501 gcctatgccc tcattttgtt acgccaagac ggccttccat gtgtctttta cggagactac
    28561 tatgggattt caggccagta tgctcaagaa gatttcaaag aaatccttga ccgcctccta
    28621 gccatccgaa aagacttggc ctatggagaa caaaatgact actttgacca tgctaactgt
    28681 atcggttggg tacgttcagg tgctgaaaat caatccccaa tcgcagtcct tatctcaaat
    28741 gaccaagaaa acagcaagtc aatgtttgtc ggtcaagaat ggactaatca aacctttgta
    28801 gatttacttg gtaaccacca aggtcaagtt acaattgatg aggaaggtta tggacaattc
    28861 cctgtctcag ctagatccgt aagtgtctgg gcagtcaata ccatctaata gctcataata
    28921 accaagctag gtccaagcgg atttggcttt tttgtattca caaaaagacc tacccaaatg
    28981 gatagatctt tacttgatta caatttacct gctactgcat ccaacaattc ttggatctta
    29041 gcttggttgc ttcctcctgc catggccatg tctggtttac caccaccacg tccatcgatg
    29101 attggtgcta attctttgac aaggtttcct gcatgaaggt cttttgtctt gcttgctaca
    29161 aggacattga ctttgtcacc gatagcggca actaggacaa gaagatcaga gtagtctttt
    29221 tgtttccagt tatctgcaaa agtacgaagg gcaccggcat cggatacaga cacttgacta
    29281 gcaatgtaac gatgaccgtt gacttcctta gcatctttga agatatcgcc tgcggctgca
    29341 gctgcggctt tttctttcaa ctcagcattt tctttttgaa gttgacgaag ttgttcttga
    29401 agtccttcta ccttgtgagg tacttccttg acttgaggtg ctttcaaggt tgctgcgaca
    29461 gctttaagag catcctcttg ttcacgatag gcttcaaagg cttccttacc agtcactgcc
    29521 aagatacggc gagttcctga accgattcct tcttctttga caattttgaa gagaccaatc
    29581 tcagaagtgt tgccaacatg agtaccacca caaagttcaa tagagtagtc accgatagtc
    29641 acgacacgaa cttccttgcc gtatttctca ccaaagaggg ccatagctcc catttcttta
    29701 gcagtgtcaa tatccgtttc aactgtcttc acttcaagtg cttcccaaat tttctcgtta
    29761 acttgctgtt caatcgcacg aagttcctca gcagttactg cttggaagtg ggtaaagtca
    29821 aagcgaagga attcaacttc gttaagagat cctgcctgtg ttgcgtggtt tccaaggata
    29881 ttgtgaaggg cagcgtgaag caaatgagtc gcagtgtggt ttttcatgac acggtgacgg
    29941 cgattgctat caattgccaa ggtatattct tggttcaagg caagcggtgc aaggacttca
    30001 actgtatgaa gggcttgacc atttggggct ttctgaacat tggtcacagt agccacaatc
    30061 ttacctgact catccaagat ttgtccgtag tcagctacct gtccacccat ttcagcataa
    30121 aatgacgttt ccgcaaagat aagagaggca gttccttctg aaacagctcc tacttctgca
    30181 ttgtcagcaa cgatagctac caatttagaa gacaattggc tagtattgta gttgaagaca
    30241 ctttctacag tgatgttttg aagagtttca ttttgcatac ccattgagcc acccttgaca
    30301 gctgacgcac gcgcgcgttc ttgttgttct ttcatggctg cttcaaaacc ttcacggtct
    30361 acagtcatac cagcctcttc agcaatttct tcagtcaatt caactgggaa cccataagta
    30421 tcatagagtt tgaagacatc tgaaccagcg ataacagatt gacctttttc tttcaagtct
    30481 gctacaatgc cttgggcaaa gtgttgacct gagtgaaggg tacgggcaaa tgattcttct
    30541 tcgctcttaa cgattttctc aataaagtca cgtttctcaa gcacttctgg gtagtagctt
    30601 tccatgattt ttccaacagt tggaaccaat ttgtaaagga aaggctcgtt gattcccaat
    30661 ttttgaccat gcatagaagc acgacggaga agacgacgaa gaacataacc acgaccttca
    30721 tttcctggaa gggcaccatc accgatggca aatgaaagtg aacggatgtg gtcagcgatg
    30781 accttgaagc tcatgttgtc gccatcttgg tcataaacct taccagacaa tttctcgact
    30841 tcacggataa tcggcatgaa gaggtccgtt tcaaagttgg tcttagcccc ttggataacg
    30901 gccaccaaac gctccaaacc agcgcccgta tcaatgttct tatgtggcaa ttccttgtat
    30961 tcgctacgag gaacagcagg gtctgcgtta aattgtgaca aaacgatgtt ccagatttca
    31021 atataacggt cgttttcaat atcttctgca agcaggcgaa gaccgatatt ttctgggtca
    31081 aaggcttccc cacggtcaaa gaagatttct gtatctggtc cagaaggtcc cgcaccgatt
    31141 tcccagaagt tgtcctcaat tggaatcaag tgacttggat ccactcccac ttcaatccag
    31201 cggttgtaag aatctttatc gtctggatag taggtcatgt aaagtttttc agcagggaaa
    31261 tcaaaccatt cagggcttat caaaagctca taagcccaag tgatagcttc gtcacggaag
    31321 taatccccga tagagaagtt ccccaacatt tcaaacatgg tatggtgacg cgcagtcttc
    31381 cctacgtttt cgatgtcgtt ggtacggata gccttttggg cattggtaat acgtggattt
    31441 tcagggataa tggtcccgtc aaagtatttc ttaagggttg ctaccccaga gttgatccac
    31501 aaaagagttg ggtcatttac aggaaccaaa cttactgatg gttctactga gtgacctttg
    31561 gtcgcccaga aatcaagcca catttggcgt acttgtgcac tagatagttg tttcatattg
    31621 tctccttatt tacttgttta atgtgattgg ctttccagca tttccacata gtcaatcgcg
    31681 acacagaggg aaatgactag gtctgcataa gcgtcttcaa gaaccgttac ggtataggta
    31741 gaggtcagat ggaagagttc cttcttaatt tccgcaatca actgatcgcg atcatccagc
    31801 aatttgaaat tcaaatccca gatattgccc tcgatacgaa gacctagatt atcaaactca
    31861 tacttatctc gccaaaaggt caacttctta cgaatgacaa aactcgagcc atccagaagc
    31921 tgaatctcaa aacgaggaag caaggtcaag atttctttac tgatctgact gacttgttca
    31981 ccagccgcat catagatggt aaaagttttg ggaatcttaa aaaatgatcc ctccacctga
    32041 taggcaattt ctcccctgtc atccttgata gcgaagcgtt cgcctccaag acgaaacttt
    32101 tgtttgacaa gaaatgtttt catcaacacc tccaaaaatc aaaagacaag ctcatatcac
    32161 gaagggcgaa aaaccgcggt accaccttca ttcaatgaac ttgtcattct cttgttctta
    32221 tgcaattgta tgattgagta gcatgacttc ctagcttaga tggctcgcag caccgccatt
    32281 tctctggact aagacaagtg aaaatcaatt ctcaactttc ttattatatc gtttttttaa
    32341 tcttgcgtca actggaaatg atctccgttg aattagacca attccctaca tctctgatta
    32401 cttttccagg atatattttt tcttactgcc gtttttcttt ttatcccaaa ttttcatatt
    32461 actaaacaca gctactagaa tatttccaaa tataaaggtg cctatcaccc aatatatgga
    32521 ctcagttgtt aggtattgtc gatccaagcc atcctttaaa tggaatagta tagcagtttg
    32581 gttaacaatc ataaaggttg gccagaaact tttgttgaaa aaagtagaca ttttcattat
    32641 ttgttgccgc tttctgtaag gttaatactc aataaaaatc aaaaagcaaa ctaggaagct
    32701 agcctcaagc tgtacttgag tacggcaagg caacgctgac gtggtttgaa gagtataggc
    32761 ttagtatact actaggcaag caaataagca aataaacaac tagaatagaa aaagataggg
    32821 ctctaaaaac tgacttctat tccttaaaaa cgaaccagct tgactgattc gtcttcttac
    32881 gtttatctcc tacttccgat acattttaaa ctgtaggaag aggtcgctat atttccctgt
    32941 ccatttatgg tcaaatttct cataaatttc taggtgtttc atggtttcaa catcgggata
    33001 gaaggcctta tcttcctttg tttcctctgg gagcaattcc ttcgctggta tgtttggtgt
    33061 tgaatagccg acatactccg cattttggag agcattttca ggtttcaaca taaagttgat
    33121 aaaggcatag gctgagtctt ggtttttaac tgttttggga atgaccatat tgtcaaacca
    33181 aagattgctg gcctctgtcg gtaccacata acgtagattt tcattttttt ctaacatttg
    33241 gctggcttca ccagagaagg tcacgccgat tgcaacgtta ttctgaatca tatagccctt
    33301 catctcgtcc gcaacgatag ccttgatatt tggagtcagt ttgtagagct tatccactgt
    33361 ctcttccaac tgctgcagat ccttggagtt gaggctgtag ccgagggaat tgagtcctag
    33421 tcccagcacc tcacgcgccc catcaaagag catgatagaa ttcttatact ccggcttcca
    33481 aaggtcatcc caatgctcag gcgcttcatc taccatggtt tcgttgtaga caattcctaa
    33541 ggttccccag aagtaaggga tggagaattt attacctggg tcaaaggact ggttgagaaa
    33601 ctctggtccg atattttcga ttccttcaat ttttgaataa tcaagcggaa ccaagaggtc
    33661 ttcgtccttc atcttgttaa tcatgtattc acttggaatg gcaatatcgt aggtcgttcc
    33721 accctgcttt atcttagtgt acatggcttc gttggagtca aaagtctcgt actgaacttg
    33781 aattcctgtt tcttctgtaa actgagtcaa gagttcagga tcgatatagt ctccccagtt
    33841 atagataacc aatttttgac tatctcgact attgatttta ctatctaaat gagtcgcaat
    33901 tccccacaag acaaggataa tcgctgcaat tcctgctaaa aatgaataga tttttttcat
    33961 gcttgctcct ccttctcacg agagataaag taataaccta caactaggat aatactaaag
    34021 agaaagacta gagcagacag ggcattgatt tctaaggaaa tccccttgcg agcacgagag
    34081 taaatctcga ctgatagggt tgaaaagcca tttcctgtta caaagaaggt cacggcaaag
    34141 tcatctaacg aataggtgaa ggccatgaaa taaccagtaa tgatagacgg agtcaggtaa
    34201 ggaagcatga tttccttgaa catctgaaat tgactagctc ccaagtcata ggccgcatga
    34261 atcatgtcgc cattcatttc cttgagtcga ggcaagacca tcaagaccac gataggaatg
    34321 gagaaggcca cgtgactaga tagaacggtc aaaaagccaa gtgaaaactt gagttgggta
    34381 aagagaatca agaagctagc accaatcata acgtcaggcg caaccatgag gatattattg
    34441 agtgatagaa aggcttcttg gtatttctta cgagactggt agatgtaaat ggcaccaaaa
    34501 gtcccgataa tggtcgctat caaggctgat aggaaggcca agaaaaatgt ctgagccaaa
    34561 atcagcatga gtctcccatc tccaaacatg gtttcaaagt gagtccagct aaaacctgta
    34621 aagctattca tatcatcacc agcattaaag gcatagccaa tcaagtaaaa gataggcagg
    34681 tagaggacca gaaagaccag tcccagataa aggttggcaa attttttcat cgttctctcc
    34741 tttccttagt cacccacatg gtgatgaaca tggtcaggat gagaatcaca ccgatggttg
    34801 aacccatacc atagttgtca ttggttagaa aattctgctc aatagccgtc cccaaggtga
    34861 taacgcggtt cccaccaatc aaacgggtca gcatgaagag actcaaactt gggataaaga
    34921 ccgactgaac cccacttcgc acaccgttca tagatagagg gaagatgaca tgacggaagg
    34981 tctcccactt agttgcacca aggtcataac tagcattgat gagattatta tccatgtcgt
    35041 ctaagacatt gaaaatcggc aaaatcataa aggggagctc gatgtagctt gcgacaaaga
    35101 taaaggaaaa atcggtaaaa agcaactgtt gtgaaccaat tccgataaat tccaagaatt
    35161 ggttaataga gccattttga ccaaaaatcc cgataaaagc ataggcttta aggagcaaat
    35221 tgatccaggt aggaaggata atcagcatga gccagagttg acggtgcttg agacgggtca
    35281 aaaagagggc tgttggatag ctgataagca aggtcacaaa ggtcacaatc cctgcataaa
    35341 gcactgagtt gaaactcatt ttgaggtagg tcaagttttg tgacgcaaag taagatttat
    35401 aattttctaa actaaactgg ccttcaatgt tgaaaaagga ttgtccgaaa atcaagacca
    35461 agggtgccaa tacaaagagg gcaatccaaa gcatgtaggg cactacaaag agtttagagc
    35521 ttgttttctt catctctttc ctcctcgatc gcattgatca gacctgcttc ttgctcttcg
    35581 atttccacgt attcttcgat acgagcatcg aactcttctt cggtttcatt gagacgcatg
    35641 atgtggatgt cttctgattc aaagtccaga ccgatttcct cacccacgat ggccttacgg
    35701 gttgagtgga tcatccattc atttccaagt tcgtcatagg cgataatttc ataatgaact
    35761 ccacggaaga gctgggtgtc gaccttaact tggagtttgc cttcttcagg aagggtaatg
    35821 cgcaagtcct ctggacgaat aacgacctca acaggttcat ttggcttcat cccaccatca
    35881 accgcttcaa agcgtttgcc gttaaattcg accaagtagt cctcaatcat ggtacctggc
    35941 aagatgtttg actccccgat aaaggtggca acaaagtggt tgattggctc atcgtagatg
    36001 tccacagggg ttccagactg gacaatctcg ccatcattca taacgaaaat ccagtcactc
    36061 atggcaagag cttcttcctg atcgtgagtg acaaagacaa aggtaatgcc caatcgttgt
    36121 tgtaattcac gcaattcgta ctgcatgtct gttctcaatt tcaagtccag cgctgataaa
    36181 ggctcgtcca acaagaccac acggggttgg ttgatgatag cacgggcgat ggccacacgc
    36241 tgacgttgtc ctccagaaag tttgcggatg gaacgttttt cataaccttc caactgaacc
    36301 atcttgagaa cttccgctac acgctgctcg atttctttct tatcaatttt acgcaagcga
    36361 agtggaaagg caacattttc aaacacattc atatgtggga acaaggcata ggattggaag
    36421 acggtatgta cgtcgcgctt gttggttgga atatcattga tacgaacacc gtctagcatg
    36481 atatctcctg tcgtcgcatc cagtaaacct gcaataatgt ttaggatagt tgatttcccc
    36541 gaaccagatg cacctagaag ggtgtagaat ttcccttctt ccaactcaaa gttgatgtct
    36601 ttgagaacct tggtgttgct gtcttcaaaa actttagaga cgtttttgaa ttcgataatt
    36661 ggttttttca attggcataa attccttctt tttcatagat taaccgatcg gggctctgtc
    36721 aggtccccac tacctcttgc agggagtaaa accacctgca tacatcttcg ctaccgatag
    36781 gctttcaccc aagatccgga cttctctttc aagcgtaata cctgagtgtt ccttgacttt
    36841 ttcgataacc gattggatca agtcctcgta gtctttggcc gttccatctg cgacattgat
    36901 cataaatcct gcatgctttt ctgacacttc tacgccaccg atacgatagc ctttcaagcc
    36961 agcttctgaa attaactgac ctgcaaaatg cccgactgga cgcttaaaga ccgagccaca
    37021 agatgggtat tccaaaggtt gcttgagttc acgtaggtgc gtcaagcggt ccatttcctg
    37081 cttgataacc tgatgggttc ctggagctag ggcaaattta actgacaaga caactgcacc
    37141 agactcctga atagctgaat ggcggtaacc aaaagccaag tctttagcag acagggtttc
    37201 gatttctcca tccttggtca agaccttaca agactgcaag atgtgagcaa tctcgccacc
    37261 ataggcaccc gcattcataa agacagcacc gccaacgctt cctggaatac cacaagcaaa
    37321 ctcaaagcca gttaaactat gacggagggc aatgcgagtt gtttcaatca agttagcccc
    37381 agcttctgct tcaatggtat agccatcaac agaaacgtta ttgagcttgt cacacaagat
    37441 gacaaatcca cgaatcccac catcacgaac gatgatattg cttgcattgc caagaaccat
    37501 ccaagggata ttttcttggt tggcaaattt cacaaggcga gccaactcaa aacgatttcg
    37561 tggaaagacc aaataatcag cctctccacc tacttttgta taactatagc tatgcaaggg
    37621 ttcctgaaaa cggatatcaa ttccttctaa gatttcaagc attttttctc ttacagacat
    37681 gtcactcttc cttttccaaa attcattcca ttataccatt tttagagaca tttgacgacc
    37741 ataaaaatac cttgtttgga ttttgcataa gaaaaagagg ttcccccctt tttatgattt
    37801 tttacaaaag atttccttgg ttccataggc gaccagaacg agctccagtg ctagaatcac
    37861 ttcaaccaag actggatttg tcaaccagcc tacttggaaa agagatggtg ccagatcaaa
    37921 gaaggcatgc aagccatagg ctgttaggag ataaatccat ttcttctggc gaacagcttg
    37981 gtaaacccaa actgtcaaaa gtaattggaa accaagcgcc aagattcgct caaaaccaag
    38041 caaataaatc tgccagaccg aaagtgactg aatggttttt aacatatttt cagacagtaa
    38101 ttgcataacc tgtggattct gagtttgaac tgccgaaaga acaatgtaaa gattgagtaa
    38161 actagtaagg cctagaaaaa tcaactccaa gccaccatgc cccagtccat aggccaaggc
    38221 gtctgccttt tccaaacttc tctttttctc aaaccatttg aagaaaacaa gacgagccgt
    38281 ttcctcaaaa aatgctgcca tggctaggcc atagataata tagataagcg gatgatcttg
    38341 caagagggca atactaccgt ctttttgagg gtgcaaaatc aagatatgca ccagtttttc
    38401 caaaatctgc gaagagacaa agaaagcgac tgcacccaag cccaagacag ctagattaat
    38461 ctggtatttc tttttggcaa accaaatgct tcctatcaga aaagctagca acagcaacat
    38521 ggtaataatg atatgaatgg tcattttctt ctcctattct gccttttcaa tatctttttt
    38581 catctcgtca acattgaact tagcaaacaa gtattgacgg tcttggactg ggaaacgttg
    38641 gtccaactgg tcaactgctc ccacctcgat aatgccttcc ttgatgacaa aatccatgac
    38701 atgtccaccg aaggtcaaat catctgatat gaagtgcaga tggtagcctg ccacactgac
    38761 cccatggaaa atctcaggcg tccagaaacc aacaatagtc cccgcaacat tgtcacgact
    38821 atattccggt tgatgggttg cgacatcagc aaacttggta tcgggtgttg acttaggaat
    38881 catacgcaca tgcatatgta aaaattcccc ccgaatcttg atagagcgga aaagattttc
    38941 cccatcataa taagactcaa ttcgttcttt caattccttg tctgtcatct caaagcgctg
    39001 gcggaaaatg acctctgcct gatgcggtac cactgcagcg taaggaataa gggcatctgg
    39061 tgacacttcc acaatttctg gctggtctcc tgaccctttg gcctgataag ccttgccatc
    39121 caagacaatc aattccccat caatggaatc caaggttccc aaaccaaggt caccatgttc
    39181 tagcaattct cctactgtca tagtaccacc ataaaggcca gccatcaagg ctccaagagt
    39241 attgtattga aataatttca ctggttcctg cacgttctta tccattcact ttcttgtctg
    39301 ttattctata aatcttactc ctaagtatac cacatttgcc cctagatgtg aacgagagaa
    39361 acgttctaga cattgccaag aaggaaaaaa aagggtacaa tgtaacaaaa tcaagggagg
    39421 tctggaatga agaaacaaag caagtacaaa gaggtcgttt cctatctgaa aaatggtatc
    39481 gagtctggac gatttccgac gggtagtcgc ctgccttcta tccgtcaact gagccttgac
    39541 tttcactgca gcaaggacac cattcaacga gccctgctgg aattacggca cgaacaatac
    39601 ctctatgcca agcctcagag tggctactat gtattagaac aagggcaaca tcaagaccta
    39661 gaaatcgagg ttaccgacga acatgccagt gcctatgacg atttccgact ctgtgtcaat
    39721 gaaaccttga ttggccgaga aaactacctc ttcaactact atgacaatca agaaggatta
    39781 gaagacctaa gacagtccat tcacaaactc ctctttgagc aagctctcta ctgcaaggct
    39841 aaccaactag tactgacttc tggaacccaa caagccttat ttatcctctc tcaaatatcc
    39901 tttcctagac aagccaagga aatcttggtg gaacagccaa cctaccatcg gatgaatcgc
    39961 ctcttgattg cacaggggct ggactatcaa acgattgaac gaggcattga tgggattgac
    40021 ttggaggagc tggaaggcca cttcaaaaca ggaaaaatta aatttttcta caccattccc
    40081 cgatttcact atcctctggg acattcctat tctgagcaag acaaacgatc tattcttaac
    40141 ttagctgcca agtatgatgt ctatatcgta gaggacgatt atctgggtga tttggactcc
    40201 aagaagggcc aaaccttcca ctatcttgat acagaggagc atgtcattta tatcaagtcc
    40261 ttctcgacca gcctttttcc tgcccttcgt attacagcac tcattcttcc aaatgctatc
    40321 aaagaagcat ttgtggccta caaaaatatc ctagactacg acagcaacct cattatgcaa
    40381 aaggccctgt cactctatat tgacagtcaa ttgtttgaaa aaaatcgttt ggctcgcttg
    40441 accaatcatg aatcttacca aaaacaaatc gaggaaagga taactaaaac accttgtccc
    40501 cttcctcatt atcccctaca cgatggttta ttgctagacc tgagacagta tcctaaaatc
    40561 gccagtctca aacacagtca actgggcttg gacttctttg aagaggccta tttgagcacc
    40621 tgtccttatc aatttgccaa ggtgtcccta gacaatctgg aaaatgtttt aaactattta
    40681 aaagcagaat tggaatgaca tccaactctg ctttttctta ttcttcaact tcagttagac
    40741 ttgctgcttt ttcaagatag ctttggtaag ttccttcatc cttaagtttt tggatgacct
    40801 tgtctaccac ttctttcaaa tcatcactat tttttctaag agcaacggca ttggcgtcgc
    40861 cgtccttcat cttcaagctg acagttgcga cagctaagcc agcgttttta gcagcataac
    40921 taagtgcaac aggctcatcc atatgaacag catctatttt tccagcctgc aattcattga
    40981 ctgcttcacc catattagtt agggaagtta attgagcttt tggcaattgt tccttgacca
    41041 ttgattctgg aacagtccct ttttgggctg caatattagc actttctagg ctagttaaat
    41101 ccttgtattt ttccacatca gccttacgaa ccaagaaact aatcttgttt tcatagtatg
    41161 ggattgaaaa atcaaagact tcttttctct cgtcagtagc actaattcct gcaactgcta
    41221 ggtcagcctt accagtttga agactggtca aaacattgtc aaaactcatg cttaagattt
    41281 ccaacttaac cccaagttca tcagcgatag cctgagccat gtcgatgtct gcaccgacta
    41341 cctggttctt tccatcaacc aatgattgaa attcaaaggg tgcatagtca ggactggttg
    41401 ccacaactaa tttccccttt tgcttaatgg cctcaacagc tgactgagaa ccattagaac
    41461 ctgactggca agctactaag aagaaacttg caagaaaatt acataaaaca aatatccatt
    41521 tttttgattt cataaataaa caacctttct gttaattttg tataattata acgatatcca
    41581 agttacttgt caagtgtttt ttaaattttt atctcaaaaa tattttttcg ttcaaaaaaa
    41641 ggagccatca gttgatttca agctcctttt tatacagaat taaactattt tatagttcga
    41701 caatcttacc tgtttcaaag tagacaaccc attcacagat atttttagca tagtcaccga
    41761 tacgctccaa gtaggaaata acttggaaat aatcacgacc cgtaacaatg gcttctggat
    41821 ttttcttaat ctcttcagtc gcaaggtcac ggatagtttc aaaatagtgg ttaatttgct
    41881 catccatgga ggccacccgg tatgcgtcgt caacagaacc attaagataa agatcaagtg
    41941 ctgcttccac aacgctttta acttcacgtc ccattttttt aatttcttcc tctacagctg
    42001 ggatgcgttc ttcccccttc atacggatgg ttgcctgggc aatggctaca gcgtgatccc
    42061 ccatacgctc cacatctgat acagccttaa ggacagtcaa gactgtacgc aaatcttgag
    42121 agactggttg ttggagtgcg atcatttcaa atgatttctt ttccagtttc acttcgtatt
    42181 catttacttc tgcatcatct tcgatgacct cttttgccag gtcacggtca tgcgtgacaa
    42241 aagcacgtac cgtacgattg atttgtgaga gcacttcttg tcccatagcg tagaactggt
    42301 tatgtaattt ctctaaatct tcttcaaatt gagatcgtaa catctttcat ctccttatcc
    42361 aaattttcct gtaatatagt cttccgtttc cttgtgttgg ggatcaagga acatctgctt
    42421 ggtatcatta aattcaatca aatctccatc taggaaaaat cctgtcttat cagagatacg
    42481 tgaagcttgc tgcatggaac gggttaccag aagcatggtg tacttgtctt ttagaccata
    42541 caaggtttcc tcaattttac cagctgaaat cggatccaaa gccgaagttg gctcatccaa
    42601 gaggatgatt ttaggactag ttgccaagac acgggccacg cagacacgct gctgttgacc
    42661 acctgacaat ccaatagctg aatcatatag acgatccttg acctcatccc agatagaggc
    42721 accttgcaag gctttttcta cggcttcatc cagaacctgc ttatccttaa ttccattgat
    42781 acgaagcccg tagacaacat tctcatagat agtcataggg aaaggattag gttgttggaa
    42841 aaccattccg atttccttac gtaattcaac cgtatctgta cgcggactgt agatgttgtg
    42901 accattgtac accacggatc cagttgtggt cacctctgga ttgagatctc ccatgcggtt
    42961 gagagacttg aggagggttg acttccctga tccagatgga ccaatcaagg ctgtaatttc
    43021 cttaggttgg aaagataggg aaacactatt caaagccttc tttttattat aatatacgga
    43081 caggtctgat acctgtaaaa tcgcatctgt catacggttt cctttctaac caaagtgacc
    43141 agatacatag tcattggtgg actgtagctt ggcattttgg aaaatagttg cagtcttgtc
    43201 atactcaatc aaatcaccca agtaaaagaa gcctgtatag tcacttgcac gagcagcctg
    43261 ctgcatatta tgcgttacaa tgatgatggt aaagtttttc ttgagctcaa acatggtctc
    43321 ttctagttgc atggtcgcaa tcggatccaa ggctgaggct ggctcatcca ttaagaggat
    43381 atctggctta acagagatgg cacgagcgat acagagacgt tgttgctgac cacctgataa
    43441 ggtcaaggct gacttgtgga gatcgtcttt aacctgatcc cagagggcag cctgacgaag
    43501 ggaggtttct acgatttcat ctaggacttg cttatcctta actccagcac gttcatgcgc
    43561 aaaggtaata ttacggtaaa ttgacttagc aaatggattg gggcgttgaa aaaccattcc
    43621 aatgtgttta cgcatttcat aaacgttgat ttctggacgg ttgacatcaa ttccacgata
    43681 gagaatctgc ccagttactt tagcaatatc aatagtatca ttcatgcgat tgagactgcg
    43741 taagtaggta gatttccccg atcccgacgg accaatcaaa gctgtaattt tatttctttc
    43801 aaattgcata tcaatcccct taatggattc atttttacca tagtaaacat ggacatcctt
    43861 agtagaaagg gctacttttt cttcaggaaa ggtaaggata tgcttctcat cccagttata
    43921 tgttgacatg gcttctcctt taggcagcgg ttaatttctt gtgtagatag cttccgaact
    43981 tacgagctcc aaagttaaaa atcaggataa agatcaggag cacagcggca gaacctgctg
    44041 atacaatggt tccatctgga atagtgcctt cactattgac tttccagata tggacagcca
    44101 aggtttctgc ttgacggaag atagagatgg ggctagtcac actgaggata ttccagttag
    44161 accagtcaag agctggcgcc gattgccctg ctgtatagat cagagctgca gcttcgccaa
    44221 agatacgacc agatgccaag acgacacccg ttacaatacc tggaagcgct tctggaataa
    44281 caacatgaac cactgtctcc cagcgagaaa tcccaagagc cagaccagcc tcacgttggg
    44341 tatggtgaac gtgtttcaaa ctatcctcta cattacgcgt catctgaggc aagttaaaga
    44401 ctgtcaaggc caaggcacct gaaatgattg aaaatccata ctcaaactgg actacaaaga
    44461 tcaagtaacc aaagagaccc accaccactg atggtaaaga ggacaagatt tcaatacaag
    44521 tccgcacaaa gttggtaaca ggaccttttt tagcatattc agccaagtaa atcccagctc
    44581 ccatagaaag aggtacagaa ataatcaagg taatgaccaa taggaaaaag gaattgtaaa
    44641 gctgaatgcc aatcccacca cctgcttgaa aagcagaaga ccttccagtc aagaaagacc
    44701 aagagatatg gggcaagccc cgaaccaaga tatagagaat caaggaagcc aagattgtca
    44761 caatgatgct agcaatcgta tagaggacag ctgttgcaag tttatctaat ttcttagcgc
    44821 gcataatttt tctttcctct ttctttcgta atcaatttaa tcacactgtt aaaaactaaa
    44881 ctcatcaaga gcagtaccaa ggccagtgac cagagaacat tattatttac agttcccatg
    44941 acagtgttcc caattcccat agttaatata gaagttaaag ttgcagctgg tgtggtcaag
    45001 gaagttggga taacagctga gtttccgaca accatctgga tagctaaagc ctcaccaaag
    45061 gcacgcgcca tcccaaagac cactgcagtg aaaataccag aacgggccgc cttcaagatc
    45121 acacgccaga tagtctgcca gcgagtggct cccatagcga aacttgcctc acgataataa
    45181 cgaggaaccg cacgcaagct atccgttgtc ataaaggtta cggtcggcaa aatcatgaca
    45241 aagaggacgg aaatccctga caaaatccca aaaccagtcc caccaaagac actgcgaaca
    45301 aagggaacga cgacttgcaa gccaataaat ccgtacacta ctgaaggaat cccaaccagg
    45361 agttcaatag ctggttgcaa aatcttcgcc ccttttggtg atacttcggt cataaaaact
    45421 gctgcaccaa tagcaaaggg tgttgcgata agggctgaga gaatggtaac gataaaggaa
    45481 cccaaaatca taggaagggc accaaattct ttactagaag gattccaagt tcctcccaaa
    45541 agaaagtcaa agatattcac accattgaca aagaaggtcg acaagccttt ttgcgctacg
    45601 aaaaccaaaa tcatggccac aaggatgact atcaaagaaa gacaggcaaa ggtcaaacct
    45661 tttcctaatt tctccagacg agaattcttt gatggaagca acattttctt agctaattct
    45721 tcttgattca ttattgtctc ccttccaaca ctgtcacagt tccggcagca tctttttcaa
    45781 ccttcatttc cttaatcgga atatacttca atcctttgac aatcccttct tgggtctcat
    45841 ccgagagaac aaaattgaga aattctgcag ctaactcatt gggctgcccc aatgtataca
    45901 tatgctcata agaccacaag ggccaattat tgctacttat attttctgga cttaagtcat
    45961 agccattcaa cttcatgctt ttgaccgaat catctatata ggtaagagat aaataagaga
    46021 tagctcctgg actttttgat acgattgatt ttaccgctcc atttgaatcc tgctcctgac
    46081 tttgcatggc agactgacct tccataatga cagtatcaaa ggtagcacga gagccagagc
    46141 cggctgcccg attgataaca gagatgggta agtccttacc accaacctct ttccaattgg
    46201 ttacctcacc tatgaagatt tgacgaagtt gctctgtcgt taggttatca acatcaacct
    46261 ccttattgac aatcagagcc aagccagcta ccgcgacctt gtggtcaaca agagcagaag
    46321 catcaattcc gtctttttcc tcagcaaata catctgagtt tcctatatca actgccccag
    46381 actgaacctg ggacaagcct gtaccagaac ctcccccttg gacattgacc gtttttccaa
    46441 catggatcgt gccaaattca tctgccgcta cttcaaccaa gggttgcaag gcagttgagc
    46501 caacagccgt tatggattct ccacgatcaa tccagctagc acagcctact aaacaagccg
    46561 tcagccaaaa agcgataaga gacagagcaa gcttttttct ttttttcact gtttttctcc
    46621 tcgaaaataa ttatgaatac tgtgaatttt ttaagtagtt ctttatgagt tgacgcatga
    46681 attcttacca aatttctgcg caattgatta tttatataat ataggctata ttactctttc
    46741 ctaacctcct tttttcatat gtggataaaa tctcttgtct atcccttccc ccattgtcac
    46801 ccattatagt catttcgtgt ctctttttcc cctttttaat gcaagggaaa ttactctcct
    46861 tagatgataa tccaaaagct agaaaggtat ctcaaatctc tctactctcc cagactagtt
    46921 tacaactaaa aggaaaagat tctattttat gagaaatcta gtttacaagc ggtaagaacg
    46981 ctaataacta aacttcttgt actctttgaa aatctcttca aagcagtgtt ttgagctatc
    47041 tatggctagc ttcctagttt gctctttgat tttcatcgag tagtaaaact acatgtgatg
    47101 gcaatcaaga tatcaagaat catcctacta aaaaaatcca tactttcact ataacataga
    47161 ataagatatt tgactagcat tttcatttga atctgaggcc ttttggaaaa taatttttca
    47221 aaacatttcc agtaaccttt gcaaagccca agccattgcc tttaaccaaa acttggtacc
    47281 aaccatttgg cagactttct gccagctgaa cggtttctcc agccgcatac ttgacaaact
    47341 cttcttggcc aatttcaacc gactgttcga cctgactcgg tttcaaggct aaaccaagag
    47401 cgaaactggg ctcaaagcgt ttcttcttaa aagtacccag atgcagtcca ttgcgagcaa
    47461 tcttgagctt ccctaaatct ggcaaaagtt ctggcaagag ataaagctgg tctccaaaaa
    47521 tctgcaagat acccggtaga ttgaccttca aatggttttg ggcaaattcc tgccacaagg
    47581 caacttgttc acggctgagg ttactcttac ttgccttaaa tttaggagct ggattgttac
    47641 ccttaaactg tagatgggca acaaactgac cctctccctt aaactgatga gggtacatcc
    47701 gagccgtttc tggcaggtca ataccagcta ccattccatt gatatgctct actggcaaca
    47761 agtcaaaatc atactcttcc agcaaccaat tgacaatctc ttcgttttcc tcgggtgccc
    47821 aggtacaggt cgaataaacc agacgaccac cttcagctaa catggtcact gcatcctcca
    47881 gaatttctct ttgcaagcta gcacattgac tcggataatc taagctccaa tagtccatag
    47941 catcaggttg cttacgaaac attccttcac cagagcaagg ggcatcaaga acgattaagt
    48001 caaaatagcc tttaaagacc ttgaccaagc ggtcggcaga ttcattggtc accacgacat
    48061 ttgtcgctcc aaaacgctcc atgttttcaa ccaaaatctt agcccgtttg cttgaaattt
    48121 cattggaaac aagtagcccc tcccctgcta gataggctgc cagttgagtt gatttgcccc
    48181 ccggtgcagc agccaagtcc aagaccttca taccaggact gggttgggct acttgagcca
    48241 ccatttgagc agcaggttct tgcgaataaa ctaaacctgt agcatgctca ggcgatttcc
    48301 ctgaaacctt cccatagtgg ccccaagggg tttgagtaat ggcatcagaa aaggaaagtt
    48361 gctcttcttt taagggattg acccgaaagg ccgaaaccgc ttcctcctca aaagaggcaa
    48421 gaaaatctct tgcctcatct cctagtattt ctttatattt ttcaacaaat ccttctggaa
    48481 atttcattta agttcttttc ctttcgtaaa tataggactg aatttcctcc tgcatctcaa
    48541 gaggcaccat catgaccggc tgtctggttt gaaaatcagg agcttcacca aaaagggtca
    48601 caacccgata gcccagactt tcccctaaaa tactagctgc ggcataatcc catggttgca
    48661 gataggtgag ataggtcaac aaacgccctg acaaaatctt ggcaaaacta atggccgcac
    48721 ttccatagac acgaacacca agaaccgctc ggctcaaatc agccagcccc cattcattgg
    48781 tttccagcat accactattc cctgcaatga gaaaatctcc aagtggttta gttttaaaag
    48841 aagctagggg cctatcattt agacaaactg gaaattcccc accaccgtgg taacaatccc
    48901 ctttgaccac atcataaatc agaccaaact gtccctgacc attttcaaaa taagccatca
    48961 taacagcaaa atcttcctgc tgggctacaa aattattggt accatcaatg ggatcaatga
    49021 cccaaacctt gccctcttga accgaggctc gcagacaacc ttcttcagca caaatcttat
    49081 cctcaggata acgggacaaa atctcaccaa ccaagagttc ctgaacttct ttgtccagtc
    49141 tggtcaccaa atctgttgga gaggacttgg tttcaacacg caagtcttcc tgcatatggt
    49201 caagaatgta ctgacctgct ttcttaacaa gctctttagc aaattcaaat ttacttttca
    49261 agagaaatct ttcctttccc tttttctttg gcagcctgaa ctgctcggta aagtgaatag
    49321 ccactaaccg tttcaaattc tcgtcccaaa cgtttctctt cgctcttgct tggcacgacc
    49381 gctttgaatc ccttatagga gtccagtaac tttttagcct ctactttgcc ttcataggca
    49441 gcttcaacat cattaaaaaa agaaagcact gaagcaagtt cttcagtgct ccacgacaaa
    49501 tctagtgggt aactatactg tttgttcatt aactaatacc agctctcatt cttgcttctt
    49561 ttagttcttg cttacgataa ctacgaggga gaaaagcacg aatctcatct tcattaaaac
    49621 cgatttgcat acgcttggca tcaataataa ttggacgacg caaaagacta ggatactgct
    49681 caatcaaatg aagcaattcc gataccgaaa tactctctac atcaatattc aatttttgaa
    49741 aaatttttga acgagttgaa atgatgtcat cagtaccatt ttcggtcaag gaaaggatgt
    49801 gttgcaattc ttttcttgtt aaaggactgg tcataatatt gtgttccaca aagggaacct
    49861 tatgtttttc taaccaggtc ttagccttac gacatgatgt acagctcggt gatagaaata
    49921 gtgtaatcat gcttttctct tcttatctat actttgctac ttctattata caaaaaaata
    49981 aggcgcttga ctagggattt ttagaaaaaa agcctatttt ttcaggaaaa ataggctgtt
    50041 tgcgaacgat tgacacaatt ggatttggtt aattcactct taacgatggt tttaaacgat
    50101 atatatattt atatatgtaa attaaaaaca tctttccttt cacttcctac gacttttcag
    50161 acacagatag ccaaagaagc tttcatagag ggcaaaaaag aggaggaagg catgaagaaa
    50221 gaaggtctct ggcaaaatca taataacagg atccttggct ggatcaaaaa gccaggtatc
    50281 atctcccaca aagagaattt gatggaaaag agtaaagaat tggtcaaaac caatcaaaac
    50341 tcccccaagt ccaatcatca caggtaagac tactagagcc aggagacttt ttcgataaag
    50401 agacaaaaag tcctttttca caatcctatt gacaaagaca tagaaacttg gcagtgtcac
    50461 tagagctact agctgaacca aatgaaagag attcttgacc actgcgaaat ggtgcaaacc
    50521 agctgctgac gaacgaaaat caggcatctg taagacctga ctaaaaggat tggtcagata
    50581 attcatcaag atatgaaaat tgtattgaat ggtttctggt tttagataga ctcgattcgt
    50641 taagtttagc cactgaatct ccataggata gaaaatccaa gccagataaa tggtcagaag
    50701 gattgagagg gagaggagaa agagcataga gccccaaaag gtcaatttag ttttcatcaa
    50761 aatcccactc cgcaaggcta gaaaccacat gtgtcggtgc gattggcagg ccagctactt
    50821 cttctgcctt ggtaaaacct gtcgtcacca agagcgttgg aatgccattg tcaatcccag
    50881 cccggatatc agtcaaataa ttgtccccaa ccatgattaa ctcttcacgt tccaaaccta
    50941 agtgctcaac tgccttgtcc ataatgatgg cattgggttt tccgatataa accggcttca
    51001 ctcgtgtcgc tacttcaagc agcgtaatca gtgagccagc acctggcaaa agaccacgtt
    51061 ccgtcgggat gttgaggtca ggattggttc cgataaaatg ggcacccttt tgaatagcaa
    51121 gagttgctgt ggcaaatttt tcatagtcga cttgccaatc cagaccaact accacgtagg
    51181 caggtttttc cttgtcttcc acataaccag ccgccttgat ggcttccttg agtcctgctt
    51241 ctccgacaac atagacggtc ttttcaagcc ccaaatcatt catatagtcg atggttgcca
    51301 aagtcgctgt gtagacagtc gataggggcg tatcgatatt aaaattctga gccaacatct
    51361 ccttaacact ctctggagtg cgggttgtat tgttggttac aaagagatag ggaatgtccc
    51421 gcttttgcaa ttcatgaaca aaagtctctc cagcagggat ttggtctttc cccttataaa
    51481 tggttccgtc taaatcaatt aaatagcctt tatatttcat ctatttctcc ctaagccttt
    51541 tttatttctt gccaagtaat gattgcttgg gcattgataa ccccatcact tgtaatttca
    51601 tgcttgcttt ccagtccagt ccgttcaaca gccgatgtaa tcaccccacc tggtcgaact
    51661 tccttgacat acttgaggtt gattttcttg ggaatatagt gggtcaaaaa atccgctccc
    51721 atgacctcaa aaatccagtc taagtattta ctgttattga catgaccatt catatccaag
    51781 tcgtaaaaac gaacatggta atccttgctg atcgactctt ccaaggactc atacttcggt
    51841 ccacggataa gttttttatc aaaatcagac tggtaaggag ccacaatctc aggttcaaca
    51901 gcatggactt ttcgactgtc gcggtccatg agaacaaagg tcgccatcat atggatgagc
    51961 tcctgccccg cttcattata aatagtaaag cgacggtagc aaaaaagtcg attgtagctc
    52021 aaggcttccg tttcgatggt aatttcttcc gcaaaacgag gcaaacgaac cacctcaata
    52081 tcatattcta cgataatcca gaccagatta tagtcttcca aaatggcctt atcactaact
    52141 cccagttcaa tcgactgcat ccctgaaact tgcagtgaca gcaaaattac atctggaagt
    52201 ttgatatgac cgttcatatc agccatatca aaaggaattt tcattttcat ttgataagtt
    52261 aagcccatga tcctactcca aaataaatcg ttccgctaca gtatctccca aaaagagacc
    52321 tctctttgtc atgcgaacgt ggtcaccctc aatctgcatg aggccttgtt gaaccaaatc
    52381 tctgacaatt tctccataaa gtccagcaaa agactgtcca aatttttcct caaatcgcgc
    52441 catggaaacc ccggatttct tgcggagtcc caagaacatt tcttcttcca tttgctcctt
    52501 ttgactcagg tgatcttctg taatacaagc attgccttcc tcaaccgcac tgagataatg
    52561 acgaatggga ccatgatttt tatagcgtac tccattgaca taaccagatg cccctgcacc
    52621 aataccatag tattcagcat tgtcccagta catgagattg tgacgacttt caaagccggg
    52681 tttggagaaa ttagaaatct cataatgctc aaaacccgct cgctccagct ctgcaatgat
    52741 gtactcaaac atctccgctt ctagttcctc cttaggcaga ggcaatttcc cacgtcgcat
    52801 ccgattcata aagaccgtat ggttttctaa aatcaaacta tacaaactca tgtggggaat
    52861 atccagtcca atggctttag ccacattttc ctttacttgc tccatggtct gaccaggcag
    52921 agcataaatc aaatcaatgg agatgttgtc aaaaccagcc agtttcaggc gatcgatatt
    52981 ttcataaata tccttctcca aatgactgcg cccaatcttt ttcaacatct tatcatcaaa
    53041 ggtctggaca cctagcgaaa cacgattgac agccgaattt ttcaaaacag ctatcttatc
    53101 cgcatccaaa tcgcctggat tggcttcaat ggtcaactct tctaagacag acaagtccaa
    53161 gtttttagtc aagccattca gtaaaacctc cagttgcgga gccgacaggg ctgtcggtgt
    53221 tccaccaccg atataaaggg ttgacaactt ttcaatatca taagaacgaa actcttccag
    53281 cagatgctct aaatagctgt cgactggctg atttttgatg aagacctttg aaaaatcaca
    53341 ataataacaa atctgggtac aaaatgggat gtgcacatag gctgacgttg gttttttctg
    53401 catagtaatt attataccac aaagactaga ttccagataa aaatcaccat ccccagatac
    53461 atagtccgtc cggagatggt gatggtttat tcttctgtta tatcaatcac aatctcttct
    53521 gagtcatcaa gagcttcggc tttttcttgc cattgctcct tgagattatt taattgattt
    53581 tttgatgctt ctgtcgcttg aaaagcatag gatttagctt gagcaagtat actgtccaca
    53641 gtgatttcac ctgactcaac ctgttctttt gttttcagaa caaaatctgt agcctgctcc
    53701 ttaacttctg tcagtttttc acagacttgc tccttggcat actccggatc ttctctcaaa
    53761 tcatctagaa aatcttgagc ctgactgcaa acttgtttgc ccttatcact tgttaaaaac
    53821 aaggcaagag ctgcacctga aacggttcct aaaaggattg aggataattt acccataagg
    53881 attctccttt tttatttttt gaaaaattta cttgcaagac gaagagctga cagacttgca
    53941 ccagtcttga gtgtttttga accagctgat gaagctttct tgctcaagac acgcgcatgg
    54001 tcattgaggt ctgaaacaga tagagataaa tctgcaacag cactgaagag tggatcaatc
    54061 gtagccacct tgacattgat atcatctgcc aagacattga ccttagccaa caactcattg
    54121 gtgtgatgca aggtcacatc cacatctgaa gtcaaggttt taatcgtctt ttctgtttca
    54181 tcgatgacac gaccaagctt ttgtacagta atgatcagat agaccaaaaa gacaatcaaa
    54241 gctagggcaa caagaatata tgcaacttct aacatttagt tttcctcctc tgtaatatag
    54301 taaggggcct tctttcgatt ttgataaata acgatcatta taccgagacc gataaggaca
    54361 actgacagcc attgggacac tcgaaggccg aagaacatga gactatctgt tcgcatacct
    54421 tcgatgacca tacgaccgaa accataccaa atcaagtaaa aggccgtgat atgacctcgt
    54481 ctgagactct tccatttccg tctaaaaatc agaatcaagg caaagccaag cagattccat
    54541 agagactcat aaaggaaagt cggttgacgg tagctcccct caatatacat ctggtcacgg
    54601 ataaagccag gtagataatc cagattatcc actgttgcac cataagcttc ttggttaaag
    54661 aaattacccc aacgccccaa actttgagca atcataacgc taggcgccgc aatatctaga
    54721 aaatcccaag tattgatgag tttacggtca gcaaagatat agagcacaag agccccagtt
    54781 atcaaaccac cgtaaatggc caaaccacca ttccaaatgg caaaaatctc tcctaaattc
    54841 tgactatagt aatcaaatcg gaaaataaca tagtagagac gagctcctaa aatagccaag
    54901 ggaaaggcta ctaagataaa atctaaaata tcgtctggta tgatcttctt tctaggtgct
    54961 tctttcatgg tcaaataaac cgcaagaatc aagcctgtca caatacataa ggcataccaa
    55021 cgaatggcta ggggtcctag ttgaatagca attggatcaa gcattttgca cctcatttcg
    55081 agcgatgaga cttgtcagtc gttcgtcgaa caaacgggtc gcatcaaagc ccatttcctt
    55141 ggcacgataa ttcatggcag ctgcctcaat cacaacagag atattacgac ctgttttaac
    55201 tggaatacga atacgaggaa tggctacgcc agaaacttca agttcctctg cattgtttcc
    55261 aagacgatca aaggtcttat gcgtatcgta attttccaaa tagacagcaa gctgaacctg
    55321 tgaagaatcc ttgacagcac tcgcaccgta gagactcata acatcgataa taccaacccc
    55381 acgaatttca atcaagtgtt tcaaaatttc agctggttca ccccagagag taatctcatc
    55441 cttggcaaag atatcgacac ggtcatctgc taccaaacgg tgaccacgtt tgacaagctc
    55501 aagacctgtc tcgctcttac caattccact atctccctga atcaagacgc ccatcccata
    55561 aatatccatc aagacaccgt gcacactggt acgttctgcc aaacgagaat ccagatagct
    55621 agataactct ccagataaac gactggtagc tgcacggctg gttaaaatag caatcttaca
    55681 ttctctagca gcctttaaca tctcctctgg aaccaccaaa ccacgggcaa caatgactgc
    55741 tggtgtctca gatagaaaca tttttttcaa aacttcataa cggctgttgg aaggcatgct
    55801 gatcagataa gaccactcct tcatccccaa aagttgaatc cgctctggtg tgtagtagtc
    55861 aaaatagcct gtcatttcaa gaccaggtcg cgtaatatcc gctgtattga tttccttttc
    55921 aagcaactct ggttcaccat agacaatatc tagtctaagc ttttcaatca cttcttttac
    55981 taaaaccgac atcatttcct ccttcaaatg agttcttctc tctattatat caaattgtag
    56041 gaggaagttt cagatttttg caggctttgg agtatttatt taaaagaaaa aggactagat
    56101 ttctctagcc tttcattcca attagaattt tttacgttta cgagctactt ctgatttacg
    56161 tttacgtttt acagaaggtt tttcatagaa ttcacgtttg cgtgtttctt gaagagtacc
    56221 agctttagta accgcacgtt tgaaacggcg aagtgcgtcg tcaagagatt cattcttacg
    56281 tactactgtt ttagacattt ttttcactcc cttcaagttc gatatctatt tcattctaca
    56341 cgtaaaagga ataattgtca agcaaaaatg ctgtttaatt ttgatttttt cttccattta
    56401 tacaagagtt gaaagcgttc aatagaacat tgctttttta tttttcgagt aagctaagcg
    56461 cttcagcatc tgcgatgatg gttacatcag ggtgattttg gaggctactt gcaggtaggt
    56521 tctcagtcac tgggccagat actgttccgg caatggcttc tgctttcgac tcaccgtaag
    56581 caaaaagaat aatagacttg gcatccaaaa tgtttttaat ccccattgaa atagcttggg
    56641 ttgggacgtc ttcaatcttg gcaaagaagc gtgcattggc ttcgatagta gactggtcaa
    56701 gttctactag atgcgtttga ctgtcaaatg gagtaccagg ctcattaaag ccgatatgcc
    56761 cattgcgacc gattcccaag atttggaggt caactggatg gtcagccaaa atttggttgt
    56821 agcgttcaac ttcagcttca gcattgtcct taacaccacg aggcaagaaa ctttctttaa
    56881 atggtttttg gttgaacaag ttttcttgca tgaagtaacg ataagactgt ggattgtccc
    56941 catcaaggcc cacatactca tcaaggttga cactggttag atttgaaaaa tcaaggtcac
    57001 tctcaacaat ttccttgtaa aattcaagtg ggctacttcc tgtcgcaagt cctagagttt
    57061 gagctccatt agccaatttt tccttcaaaa tctcaaaagc aacttttcca ccttgaactt
    57121 ggttttcaac tttaataact ttcatctttt catcctccat ttctgtctat atttattata
    57181 tggtatagac caatttttgt caagtgaaaa cgatttaatt tctaaaaaaa gagcgtccaa
    57241 acttgaaacg tgttataatg gataggatta gaacttagaa agaatgaaca gatatatgaa
    57301 tacagctgat tttgatttcc acttgccaga ggaattgatt gcccaaacgc cccttgaaaa
    57361 acgtgatgcc tccaaactcc tcatcgtcaa ccgtgagaca ggagaaatgc aagataaaca
    57421 cttccactct attattaata tgctggaacc tggtgatgcc cttgtcatga acgacacccg
    57481 agttctccct gcccgcctct atggtcaaaa agtggagaca ggaggtcatg tggaacttct
    57541 cctccttaag aacactagtg gagacgagtg ggaagttctg gctaaacctg ccaaacgcct
    57601 caaggtcggt actcgtatca gctttggtga tggccgcctc agcgctgtcg ttacagaaga
    57661 attgacccac gggggacgca ttgtccgctt tgaataccaa ggaattttcc tagaagtctt
    57721 ggaaagtctg ggagaaatgc ctctgccacc ttatatccac gaaaaattag atgaccgtga
    57781 acgttatcaa accgtctacg ccaaggaaag cggctctgct gcagcaccga ctgctggtct
    57841 tcacttcacc aaagaactgc tggcagaaat ccaagctaag ggtgttcatc tagtctatct
    57901 gactctccat gtcggactcg gaacctttag acctgtttct gtggataatc tggacgaaca
    57961 cgaaatgcat tcagagttct atcaactttc tgaggaagct gctgccaccc ttcgctctgt
    58021 caaagaaaat ggtggtcgcg tcatcgctgt cggaaccact tctatccgca ccttggaaac
    58081 tattggttcc aagtttgatg ggcaaatcca agcagattct ggttggacca atatctttat
    58141 caaacctggg tatgagtgga aggtcgtgga tgccttctca accaacttcc atctgccaaa
    58201 atcaactctg gtcatgttgg tttctgcctt tgcaggccgt gaattagtct tagatgccta
    58261 ccaccatgcc atccaagaac actaccgctt cttcagtttt ggtgactcca tgtttattta
    58321 ttgagaaaga atttctctaa atcttctaat accaataaat cgctaagata ttatttcaaa
    58381 gaacatctac aattgaaact ctagctagct gtagaagacg cctagtacat tgaaattaaa
    58441 atgcttcccc ctagcttcga aaatattgcc atagattgcg ttgactctcc aaattgattc
    58501 atctatattt tatttcagct tcctatattt tcttcgctgt ttgtaaatca aaatgcaaga
    58561 cacatgagta gcaccatatt tgttactctt atctgtcctc tcaagagact attatgagtt
    58621 atttcagaat cattcactac tttgaccctg actctcctta gtctcaaaat caaagactta
    58681 tactcttcaa aaatctcttc aaactgcgtc aacgtcacct tggattatat atgtgactga
    58741 cttcgtcagt tctatctaca acctcaaagc agtactttga gcaacctgcg actagttttc
    58801 tagtttgctc tttgattttc attgagtatt aaacaaaaag tgaacaaatc tgaattctaa
    58861 tgtacagaag actaggcttg ttcacttttt tatagtcgct ataagatgac cttatctata
    58921 gctttttata tataattata tataattata tattcagaca tactattatc aattttgtcg
    58981 cagggaggaa tctgttaacg cacccattca ccattatcat tgactctata gccatctata
    59041 cttgtattga ccgctaactc acccgatgca tttacataat accatttacc accaacttgg
    59101 aaccattgat tgactttcat agaaccgttg ctgttgaggt agtaccatga accattaact
    59161 tgtacccaac ctgttgccat ggaaccatca gtattataaa aataccacat accattttct
    59221 tgtttccagt ctgttgttgg agcaactgct ttagctggtt ctactgctac atctgttcct
    59281 tggttagatg taacagatac aggatacgaa ggaatagatg attgctcagg aacaacaact
    59341 ttttcaggtt ctctcgtccc tctccttata cgtcttttta ccatctcttt agtaatttga
    59401 cgagaagtag tttcttcaat tgttccatca cgttcatcta cagtatagat tgtagtaaga
    59461 gtaatttacc aatttctcct acttcttcta cttcttgact tttatcaaga gttgggtcat
    59521 cgagatattc tgtttcgatt ggaatttctt ggacaagaac ttggggcttg gttccttttt
    59581 taacaactct tgtttgagag tcttcttttt gacttaaagt actctcagtt acttgtccac
    59641 tctttccatc tacatcataa gttatcgttg taactgtttt cccattcttt cctagagtaa
    59701 tctcttgctc ctgtcctgca gaaaggtcat tgtctgcttc atatttagta gcacatggaa
    59761 caagaacttc ttcaaccttg cttttagctg gaactttgat aactgtatcc gtggcttgtt
    59821 ttctatcaac agtaacctgt tcggtaacat gaccagtctc tggattaaca tcgtaggtcc
    59881 ttgtcgtagt tacatagcca tcctctccat caattgtaac aggattttca ctacggtctt
    59941 ttgtttcatc tttttcataa cgaattcgcg tacttgaaat tttcttggtt actaccttag
    60001 gtttagtcgc tacttttaca ataatacccc cattgtcagc gtcatcatac tctattccct
    60061 cttctttatc tctagtatca tctctgacat attgaatccc atcagcagca tgaacaaaac
    60121 ttgtattcag attcctccta aaaataaagt tagcccgatt accgcagaac caaaaatctt
    60181 tccgagttta cgtaatgcat agcgcttatt agtattagat tttgccatta catcctactt
    60241 ctagtatagc atcttttcta tcaaacgtta aacaatatac tttatatata aaatagactt
    60301 agaatgatat attgattatt gaactaacac tttaactata tcgtaatcaa tctcatatat
    60361 aaaggattgc agacatctta tctaaataca tgctaatata tttagataca aacattccaa
    60421 cttgataatt ttcactcatc tttcatcatt ccttatacaa ctatgcagta taaatagaat
    60481 agttttctca tcagaatgag actattttaa tattagataa tttgatagaa aaaacatgaa
    60541 taaaattggt tgaatttaat tccctaactc gatagaggat tctattttaa atttaacaac
    60601 agctaggatt acactataaa aagtacatta ccacctgttc ggctggagaa tctagtcgat
    60661 tagctccctc ttagttacaa gcttaaagcg attttttaac taatactaaa ccagattaaa
    60721 gaaggaacta gaacatctgt cttgtactaa tcaatatgct attttaaagt ttcaaataaa
    60781 cttggaatgc taattattat atttacaata aatagttgac ttcgatagaa acagaaaata
    60841 gaattcaaca ttcttcccta cttataccat aataaataag atccgcaaga tagccttttc
    60901 tctctacacc attaacaatg gtttgtagat aggacattcc agccttttcc atgacacgac
    60961 ctgaagctgg gttgagactg gcataacgtg ctctgacctt ttgaaaacct gcttgagtaa
    61021 aacaaaagtc caagatagct ttcaaagtct ctgtcatcat accatttccc cagtaagcct
    61081 tgcctaacac atagccaatt tcacagctta aatcagcctc gtctatctta acgatgctga
    61141 tatctcctat cacttgctct gggttttctt ttagacaaat ggcccattta taatagttga
    61201 gattagtata ggaagcaacc caattgcgaa tcgagtttcg agtgatttcg atatcaggat
    61261 ggggatccca ggtaacatag gtcagattct cagcagatga agcccaattt tgaaacatgg
    61321 cttctgcatc actctccaca aatcttctta aaatcaaacg ttctgtctgt aatatttgcg
    61381 taccgataga tttcatgatg ctacctcact tccttatttc tatgctcgta gtaaaaaggc
    61441 tcaactcagt aacagctaga aaacgagttt gtcttctaat ttcttgacgc agtcgctgcc
    61501 tggtttgaaa tgcgctctag caagcttttt caaacctagt catcgttgca ggggtaagac
    61561 gatgaaatcg aactcttcga gttaccgaat ctgcctcatt ttcttatttc taaactcggg
    61621 gttcaagatc ccccagacct tctctcactt tcttatttca agatgagagg ctgaaaacct
    61681 ccagtggagg tttttcttgc tttttaattt cagggcaaga agctaaaaag gtccccggac
    61741 cttcttcgct ttctcatttc taggctcagg gtaaaaacct ccaatggagg tttttactcc
    61801 caaaagtcat caaatacagt gatgggtaag tggcgtttgt gttggccttt gtgccaccag
    61861 ttttcaatgg tcgcttgagc ttctgggctg attgttttgc cttctaggta gtcgtcaatc
    61921 tctgcgtagg tgactccaag tgcgacttcg tcagctaggc ctggtttatc ttcttctagg
    61981 tctgccgttg ggattttttc ataaagggct ggctctgcgc caagtttctg caagagctgt
    62041 tttccttggc gtttattgag gcggtaaaga gggagaatat ccgcaccgcc gtcaccaaac
    62101 ttggtaaaga aacctgtgat attttccgcg gcgtggtctg ttccaatgac cgctccgcta
    62161 tgggaaccag caagggcata ctgagcaatc atacggcaac gtgccttgat attccccttg
    62221 ttgaagtctg aaacaggact acctgtcgct tcaactgcag ctgtcatggc atcagctgat
    62281 tccttgatat tcacaaccaa gctgacatct ggctggatga aggctagggc tttttgagca
    62341 tctgcttcat cagcttgcac tccgtatggc aggcggacag cgataaattt gtagctgtcg
    62401 tctcccgttt cagctcgcag ttcttccata gctaattgcg ccaaacgccc tgccaaggtt
    62461 gagtcttgtc ccccagaaat ccctagtaca aaggttttta ggaagggatg ttttttcaga
    62521 tatcttttta agaaatcaat agaacgacgg atttcttcct gggcatcaat cactggtttg
    62581 acacccagct cttggataat cgtttcttgc aaactcattc ttcttctcct tcaccaaggg
    62641 cttccttgcg catcttatca atcaagtcca tcttatcttg ccatacatca cgcgccaaat
    62701 ccactggata gtgctgcgga ttgagcacac gcttatactc atcccacaac ttgtcaaatt
    62761 ccttacgggc ataatcctga atgtcagtca aactaggcaa gttgtaaact aatattcctt
    62821 ctttgaagat atccaccaag agaggaacgg catcaaaatt acgaaccgtc ttcttgatgt
    62881 atgtataggt cggatggaac atcttgattt ctgtcatgtc gctaatatcc acaccatcat
    62941 aagtgatata gtcgccttct gacttgcctt tttcacgact ggtaatgcgc cacacctgct
    63001 tcttacctgg cgtagagact ttttccgcat tattagacag cttaatcgta ttgcgcatct
    63061 gaccagtttc atcttcgatt gcaacaatct tgtaaactgc accaagagct ggctggtcat
    63121 aagctgtaat cagcttggta cccacgcccc agacatcaat cttggccttt tgcatcttga
    63181 gattgaggat ggtattttca tctagatcat tagaagcata aatcttagcc tctgtaaatc
    63241 cagcctcatc cagttgctga cggactttct tagaaatgta ggcaatatcc ccagagtcaa
    63301 tccgcacacc cataaagtta atctgatcac ccagctcacg cgccacctga atggcagctg
    63361 gtacaccgat gcgaagggtg tcataggtat ccacaagaaa gacacaattt ttgtgggtcg
    63421 cagcgtaagc cttgaaagct tcatagtcat tgccataaac ctgtaccaag gcatgggcat
    63481 gggttcccaa aacaggaatg tcaaagagct tacccgcacg cacgttgctg gttccattgg
    63541 cgccaccaat cacagctgcg cgtgttcccc agatggccgc atccatttct tgagcccgac
    63601 gtgtcccaaa ctccatcaag ggttcatctt cgataaccga acgaatacga gctgccttcg
    63661 tcgccaccaa ggtctggtag ttgacgatgt tcaaaagagc cgtttcgacc aactgacatt
    63721 gggctagagg tccttccacc tgcacaatcg gttcattagc aaaaaccaaa tccccttctt
    63781 gggcagaacg aacggtcaac tccaacttga aattgcgaag gtaatccaag aacgccccat
    63841 gataaccaag cgactccaaa taggctatat cactatctga aaaacgcaag tcttcaagat
    63901 agttcacaat tctttccaaa cctgcaaaaa ccgcatagcc gttcttaaaa ggctgttggc
    63961 ggaaatacac ctcaaagacc gccttcttat tgtgaatccc ttggtcaaag taaacctgca
    64021 tcatgttgat ctggtacaag tccgtgtgca atgtcaaact atcatctgga tacatacttt
    64081 tcctacttcc ttagctagaa acccatgaaa attttcaaga actttcatgt attccaataa
    64141 attagtacta ttatatcaca ttttagctgg attgagaaaa gagtaacaag ctattctcca
    64201 ctctccaatt catccatatc ttgttcaaat tttttctgag cccattcgcc atagctctta
    64261 agaccaagat tgccaataaa gacccacgga aggtaaatga cataagtaat gacccaagca
    64321 gacaggtatt taaaattcaa aggattgtgc tgataaattt ctatgttgaa ttgataattc
    64381 tgcaacatca aaagagccgt aatagccaag gttaggaaaa aacaacccaa aatcgtaaaa
    64441 tgaaaacgac tatagtaggt cactcccaga taacgggcac ggttaaaaaa gtaaaatgtc
    64501 cctatgatga taacgattag cagcatatta gaattaaaaa ggcttggtgc taatactgaa
    64561 atgatataag ataggagcga caaagcgatg cagatataga aactttcaga gcccgcttta
    64621 ttgatcagtt gttcttctct ttcgtctagt aattgataat aataaaatct atttttcatc
    64681 ttcttcctcc caaaatagtt ggtctagggt tttccctaaa catctgcaaa tagactggca
    64741 gagcgagaga ctgggattgt attttcccgc ctctatcaaa ccaatagtct ggcgtgtcac
    64801 cccgacagcc tctgccagtt gaccttgtgt taaatcacgc tctacccgag ctaattttaa
    64861 ttttaaattt ttagccacct tcgtcctcct tatagtttta atactcatct actctttaaa
    64921 aatccaaact aacacaagct gtcagctatt tattataacc ccattaattt gcactccagt
    64981 attatcttca gccgaaaatc agtattttag gttgtttgaa ataaacttcc tagtttactc
    65041 ttttattttt atttttattt agcattagct ttagtaggat cttttaaacg agtttttatt
    65101 gcttatattt cttgtttagt ttagttggtt tcatatcact attatataat gcttttggaa
    65161 atgagcctag tataagtcaa aaacgtgttg aatagtgaaa gcaggagcat accaatatga
    65221 ctgatttttt actgtatttt aggtatgcaa aataatacta aatgaaacta aaatgaatac
    65281 ttcttgcttt tcttgagagt gaaaaagtac aataaaatga ttgtagtgat tgccacaaga
    65341 tactgactaa tagacatcgt atttgaagcc acaaatacag gtaaagaata aaaaggaaga
    65401 agttcaattg ctttgataaa caaatcatta ctagtattca tcatcgtatt taatatatta
    65461 gggataaaga gtagtaaagc tactaaaata ccaagccact tttcaatttg tataaataga
    65521 aaatgtaaga taatagaaaa taaaacagga ctaacaaaat tgtattgact acaatagcta
    65581 ctataaaatc taatcctaaa tcacctggaa tacccaattt acttactatg actagtaaca
    65641 caatgccatt caaagcataa ataatggaag ctgagatggc atatagaaaa ttagacaaga
    65701 cgtaaatcat ccgattcttc tgttgattat aaaacaaact taccgtattg tgggaaaaat
    65761 ctctactaat gactcgatta gcatgtataa cagccattaa cataccgagc atagcataaa
    65821 agtttgaaat atgcttaata ccaagcgatg tcccttaagt ctttagaata aagaatgtaa
    65881 gcaatatcgg cggtataaac gagataagca aactgagata tattacgcct gatgaatata
    65941 aatttcttat attttcctta agaaaattca atttatttaa tttcatgatt ataaccttcc
    66001 tttattttga acgatttagg taaatatctt taagcgtctc ttttttagtt tcaaaatcaa
    66061 ctactttaat agagttttcg ttaaaaaatt taaaaagctc actactttga atattcccag
    66121 acatagtaat tctcaatccc tcttcctgaa caatatcccc aaattcttgt ttggtaatga
    66181 aaatgtctct atctgtagct gatgaaaaag ctatctcaaa caagaaatta tgactatctt
    66241 ttcctacttt ttgaaatgtc aaaagcccgt tctccaagaa aagaactctc tcacaaattt
    66301 cttcaatgtc ttctaattta tgactcgata ttaaaattcc cacgttttca tttaaagcta
    66361 atttttttag aaccgctaaa actatttgtg atgattcaat atctaaacca ttagtcggtt
    66421 catctaaaat caatatatca ggttccgtaa cgagagttag aagcaaagct aatttttgtt
    66481 ttgtacccaa agaataggtc tttacttttt tattaataga ctgagtcaaa tctaactctt
    66541 ggatcaaact tctaaatctt tcttgattgt agtcaacacc atataaattt gacaaatatt
    66601 ttaaattctc taaacctgtt ttagataaaa ataattttgg ttcttcgatt aaatacccaa
    66661 cattatcact gcttataata ttacctgaag tcggttgatt attttgaaca agaattttca
    66721 tcaacgtact cttaccaact ccatttctcc ctactagacc aacaatttca cccttgttaa
    66781 gtgcaaaatt tatatctttg agaatgattg aatgaccata atgcttactt acatttttat
    66841 tcctacatta atattcatgg tttactcttt gattcttatt gagtttaaaa agttgcgcct
    66901 ctttttaaca atattatatc atatatctaa cttgatgcaa tatataaatg tcattttgta
    66961 aaattttatt aacaaaaaac tctctacaac aaaataatag agagttttct gcttattaat
    67021 ttttttcaaa atatctaaga catcgcttct ttgtttaatt tgataggctt tgatacctaa
    67081 gctccgactt tatcacttaa aaaataaaaa agacagctaa tctcttgcgc atcaagggat
    67141 ttcgccattc tttaatctcg tttaagtgtt gtatatggag ctttgcataa ttttttaaaa
    67201 ctaaacaact acattaagca cgaactgtga cgctggttcc atcttcctta taaagattga
    67261 taagcccctc tttaagagct cgaaccatgt ctcctgattg aacgggttgt gggactttaa
    67321 tagtcaatag ttccattgga tttggagcgc ggtcgatttt attgcctttg gcatcatgca
    67381 aatcttcaat ataggtttca aaatgacgga aacctggacc ataaaactca acttggtccc
    67441 cttcgttaat gacgtttcgt tgacgaatag ttgctgtttg tgccgcatca tcataagaaa
    67501 ccacttcagc gacaaacttg tactcaggga ttttacgacg agcaccaaac aactgctcat
    67561 tttcagatgg tgtaccatag taaaatcctg tagccagttc acgttgggca accttccaca
    67621 tctcgtccac caagtcttgt ttgatagctt caaacttttc aggactttca agataggcat
    67681 ccacaaccgc cttgtagcag ttggttactg ttaatacata gtgaatagac tccatacgtc
    67741 cttcgatttt tagactgtcc acaccatttt caatcatatc tggaatgtgg tcaatcatag
    67801 acatgtcaac ggctgacatt gaaaattctt ctggaatctc accctgcaaa ctcttacgtt
    67861 ctttcccaaa tggcatatcg taaaggtcgt atttccaacg gcatgactga gaacatccac
    67921 cacggttggc atcacgcata ctctagacgc aattctaatc ttttagactt tgcataataa
    67981 ctgttaaaca gttgaaaatt aacccagttt taacaagtag tcaaaatacc agataaagga
    68041 aaaaaagtct ttaaaatctt aaaaacgcat agtatcaggt attgaacaat cttgatatta
    68101 tgcgttttat tgtgggaaga tttacttcat tttctcttgg aattgagttt tctcctactt
    68161 caaaactaga tgatttgcta tttaaaatag cgttccttat gattttggca acctggatta
    68221 aagcgagaaa aacaaaaggg gcaacttaag ctttctttat attgcttata tgttagtagt
    68281 tttagacaaa caccacataa aataggctta tcctgtatca aagataaggg atacggctca
    68341 aaagggtgat tttctaatga atcatgacac cgataacaag catagtactt tttacaaaca
    68401 tagcattgta aagcaataat atccagcttg ctatggtaat gaatgcatct tgtttgctta
    68461 tccactaaga aaccctgtgc ctctatcatt tccttttcct ttcttaagct cgaactgtga
    68521 cgctggttcc atcttcctta taaagattga tgagtccttc ttttaatgca cgaaccatgt
    68581 ctccagcttg aacaggttga ggcaccttaa tagtcaatag ttccattgga tttggagcgc
    68641 ggtcgatttt attgcctttg gcatcatgca aatcttcaat ataggtttca aaatgacgga
    68701 aacctggacc ataaaactca acttggtccc cttcgttaat gacgtttcgt tgacgaatag
    68761 ttgctgtttg tgtcgcatca tcataagaaa ccacttcagc gacaaacttg tactcaggaa
    68821 ttttacgacg agcaccaaac aactgctcat tttcagatgg tgtaccatag taaaatcctg
    68881 tagccagttc acgttgggca accttccaca tctcgtccac taagttttgt ttgatggctt
    68941 caaacttttc agaactttca agataggcat ccacagccgc cttgtagcag ttggttactg
    69001 ttgatacgta gtgaatagac ttcatacgtc cttcgatttt tagactgtcc acaccatttt
    69061 caatcatatc tggaatgtgg tcaatcatag acatatcaac ggctgacatt gaaaattctt
    69121 ctagaatctc acccttcaaa ctcttacgtt ctttcccaaa tggcatatcg taaaggtcgt
    69181 atttccaacg gcatgactga gaacacccac cacggttggc atcacgcata ctcatgtggt
    69241 ttgaaagagt acaacgtcca gagtatgaaa tacacatagc tccatggaca aaggcttcaa
    69301 tttcaacatc tgtacgtttg cggatttcag ctaattcttt cattgaaacc tcacgtgcta
    69361 aaacgacacg agtcaagcct agctctttcc agaactcaag ggtttcatag ttagtggcac
    69421 tggcttgggt agaaaggtgg atttcaaggc ctggtgcttc agtcgctgca atcataatca
    69481 aggctgggtc agatacgata actgctgcaa tcccgatatc acgcagttta cgaaaccact
    69541 caccagcacc agcttcattt ccttcgtgca taaccatatt agccgctaca tagaccttgg
    69601 caccatactt ggccgcaaac tgcacgcctt cttccatctg ttcgaaagta aagtttcccg
    69661 cacggctacg aagaccatag gcctgaccac cgataaagac agcatctgct ccatactgaa
    69721 cagctacctt tagcttctct aaagtccctg caggtgataa aacctcagga cgttttaatg
    69781 tttttgtcat gatttctcct atttgcaata taaaagtttg acatttttcc ttctcatttt
    69841 atagtaaata aaggataaaa tcaagcctag acggattgtt ttgacaattc taatctttta
    69901 gactttgcat aataactatt aaacagtcga aaattacccc agttttaaca agtagtcaaa
    69961 aagtctaaaa aagtaaaaac cagtatccca agatactgac tcgtaaaaat atataaatta
    70021 gtccttagat gactactccc actctgttgc tcctataatg gaaaaggatt gatacagtct
    70081 agaatatcgc ttttttattt attattctga tataaaactg ttagaattga ttttttgttt
    70141 tatacccaaa tatgaataga gacgtagcta ataagttgaa taacatattt ggaaaaatga
    70201 gaaatagcaa tattactaga acttttagaa acaatcaata tttaaaaaga aaaaagctca
    70261 aagaatttat taaaccatgt tataatagat atagctataa ttttatttat aacaagagga
    70321 tagaaatgac cgaattagaa agaaaaaatc gaaaaattag ctaagaaata ttctgataac
    70381 ttaaacatca aagttcaaga gagagttcgt gaaatggcaa atgataataa gagccattat
    70441 ttgatataca gagttttagg tatttcattt gaagaaggag aaaatatcga tttgtatcaa
    70501 aataaaggtc gttttttata caaatatgct ggttcatttt tagaagaagc tgcagtacta
    70561 tcctttaacg aaaaatttgg tacagaaaat acttaaaaag ttaacattcc taattctgaa
    70621 aatacaaaac ctaagacttt tgaaattgat tgtttagtcg gagaaaaaca cgcatacgaa
    70681 ataaaatggt gggatgcaac tacagatgga gaccatataa ctaaagaaca cactagaata
    70741 aaagttattc ataacaaagg atatatacca attcggttaa tgttctacta tccaaataga
    70801 actcaagcta taaaaattca gcaaacttta gaaacattgt ataacggtat tggagggaaa
    70861 tattattatg gagattctgc ctgggaacat ttaagagcag tgaccggtat tgatttactt
    70921 agtattctaa cagatattgc aaataaaaaa acaggggtaa aatcaaaatg acagtattaa
    70981 aaggagataa cttagaaata ttaaaaacta ttgaatcctc aagtattgat ttaatctata
    71041 tggaccctcc tttctttaca cagaaaaccc aaaaattatc taataacaaa aatattatgt
    71101 attcattcga agatacgtgg acttcgattg aggattacaa agaatttttg tctgtaagat
    71161 tagaagaatg caaaagagtg ctaaaaaata gtggcagtat tttcgttcat tgtgataaaa
    71221 ttgcaaatca tcatattaga ttaattttag ataatatctt tggagcagat atgtttcaaa
    71281 gcgaaattat atggaactat aaacggtggt ctaattcaaa aaagggatta ttgaacaatc
    71341 atcaaaacat ttacttttat tcaaagtcaa aagattttaa atttaataca atttttacag
    71401 agtattcttc tactacaaat atcgaccaaa tactagtaga acgaaaacga aatggaaact
    71461 ctaaaactat atataaagtt gataataatg gtaactatat tctagcaaaa gagaaaaatg
    71521 gagttcccct ttcagatgtt tggaatatac catttcttaa tccaaaagct aaagaaagag
    71581 taggttatcc tacacaaaaa cctattctgt tattagaaca aattataaag attgctactg
    71641 ataaaaatga tatagtttta gacccgttct gtggaagtgg aactacttta gtagcctcca
    71701 agattttgaa tagaaattat atggggattg atttatctga ggaagctatc aatataactc
    71761 agcaacgtct ggaaaatgtt ataaaaacaa gttcaaattt attgaataaa ggaatcgaag
    71821 catatagaac caaaactgag gaagaggaaa acattcttaa attattacag gcaaaaattg
    71881 ttcaaagaaa taaaggaatt gatggttttt tacctaaaca ttttcaaaaa aaaccgatac
    71941 ctataaaaat tcaaaaaaat aatgaatgtc tgaatgagag tatctcttta ttacagaatg
    72001 ctataaactc caaaaaactt gattttggag tagttataaa aactcattca gataatttat
    72061 tatttgattt tgatacgatt cctgaaaata taatagtagt tgaccatttt gaacttacaa
    72121 tcgaaaaatg gttaagtaaa agtcaacagt tactatagtt tgcaaattat ttacagaaag
    72181 aacaaaaaat gctctgaaac actgatttca aggcattttt tgttagttta aaattactcc
    72241 cattcttctt ttccaaacgt acaatatatc caaaaccatt caaaatacta gattctattt
    72301 tttataatat cactaaatcc acctaattat aggacgtttt cagattttta gtcccgtccc
    72361 agtcccagta ccggagaaat attgttttaa tataatatct ctttttgtct tctaagctct
    72421 taaaagcaaa agaacaagta aagagtcaag acaaggataa aaagtccata ttagggcaaa
    72481 taaaaagctt taagacagat gacaaatcta agtcaaataa gaaagaccat agcaaaggtg
    72541 cagagagata aatattggcg gtcttcggac tgcctttatt tttttatcca tttttcaaat
    72601 caaatttatt cagactatat atgcacatat acacttaaat tcatataaaa acatggcttg
    72661 taaaaaatta ctttaatcac aataatcgca tttaaaattg tgatgtttgc aagctaaatt
    72721 acggacttca cttggaagtt ttcccttgta tcttttataa tagatagaaa atttgctggc
    72781 agatgaatat ccaacagatt ctgctatctc ttttataggt agttcagtgt ttaaaagaag
    72841 agtttcagct acattcattc tttttctttg agtgtactct gtaatgcttt gacaatattt
    72901 ttccttaaat aaatttttta atttagtacc actcatttta gatatttttt caagcgtgcc
    72961 ttgatttaca ttcgttgcaa aatgatcatc taagaatctt gctacatctt caagtgcttt
    73021 atcatcatca atttcaattt tatatttttt tctatttaag tatgtgtcaa ttactatact
    73081 tatccattca tttgcctttg ctttaaagaa aaaatcagcg gcaggagcgt ccatcttaca
    73141 atttaatatt tccattgcca ctctttctaa ggcctttgta agtattattt gattcggttg
    73201 aagcaaggtt gaataaaaag attctggatt aatgttaata gatgctaaat gtttttctat
    73261 tagctctttt ttaaaaccaa tggaaacagc aagataacaa caattctcgt gtaataaaaa
    73321 aacaaaatca tcttttatat tatcaaaatc aaaagtacat aaagagtttg cggtaatagt
    73381 ttgatacgga ttaaactttt ctccgtttgc actgacaatg taacttgaat aaattgaaac
    73441 atagtctgac atactataag tgctattttg aactacttcc tctttgatat aaaaatcatg
    73501 tatatcgata atgaagctgc ctccttcata aaaccaatat aggccttctg cataagttga
    73561 attctctttt ttccaacaaa atgtatgacc tgcacttgaa tacttctcat tgtttttaca
    73621 ttcatctact ttcatataat cttttacaaa atcataatat gacataacac actatccctt
    73681 ttagacaata ttccaattag ccttattaat tcaaaactat tgtattagta attataacag
    73741 atgtataata gaaaagcaat gatagatatt atcaattaag cgaatttata tctaaaaggg
    73801 atattaaaga aaggagatat gcttatgaag atttacaaaa aactatttgc ttatgtccaa
    73861 gataagaaat atcttggggt tttggccata attttttctg ctatatctgc tgtacttaca
    73921 gtatatggat attatttaat ctacaaattt ctagataagt taataattaa ttcaaactta
    73981 tccggtgcag agagtatagc attaaaatct gttattacac taacaagtgg agcgatattt
    74041 tattttgtct caggaatgtt ttcacatatc ttgggattta ggcttgaaac aaatttaaga
    74101 aaaaggggaa tcgatggtct ggaaaaagca agttttaggt tctttgactt aaatccatct
    74161 ggtcaaataa gaaagatcat agatgataat gcagcacaaa ctcatcaggt ggtagctcac
    74221 atgattccag atagctctca ggcaatagtc acacctatac ttgtccttgt acttggcttt
    74281 atagtaagta taagagttgg cataattttg cttgctctta ctataattgg tggcttaatt
    74341 ttaggggcaa tgatgggcga gcaagaattt atgaagatat accaagaatc cctatctaaa
    74401 ctaagtgctg aaactgttga gtacgtgaga ggaatgcaag ttgtaaaaat atttaaagca
    74461 aatgtagagt cttttaaaag cttttataag gcgataaaag attactcaaa gtatgcttat
    74521 gattattccc tatcttgtaa aaggccttat gttttgtatc aatggttatt ttttggactg
    74581 attgcaattt taattattcc tatagtttat tttatgacta gcttagctag cgcagaggtg
    74641 attttacttg agcttatcat gattttattt ttatcaggag ttctctttgt ttcattcatg
    74701 agaatgatgt ggtactccat gtatatttct caaggaaatt atgcagtaga tactttagag
    74761 gcgctttacg aagatatgca aaaagacaaa ttagtgcatg gtaatgtcaa taattttaaa
    74821 aactataata tagaatttga gaatgttagc tttgcttata atgataaagc tatcattgaa
    74881 aatttatcct ttaatttaga agaaggaaag tcctacgcac ttgtcggttc atctggatca
    74941 ggcaaatcaa cagtagcaaa acttatatca ggtttttaca atgttaataa aggaagcata
    75001 aagataggcg ggatagcaat aagtgaatat tctgacgaag ccttaattaa agccatttcc
    75061 tttgtttttc aagattcaaa attattcaag aagagcattt atgataatgt agctttagct
    75121 aataaagatg cgacgaaaga tgacgttatg agagccttaa aattagcagg atgcgattta
    75181 atattagaca aattcccaga aagagaaaat acaatcatag gctcaaaagg tgtttattta
    75241 tccggtggag aaaaacaaag aattgcaatt gctagagcaa ttttaaagga ttccaaaatt
    75301 attattatgg atgaagcatc agcatctatt gacccagata acgagtttga attgcaaaaa
    75361 gcttttaaaa atcttatgaa ggataaaaca gttatcatga ttgcacacag gctatctaca
    75421 attaaagacc ttgatgaaat tattgtcatg gatagtggaa aaattataga aagagggtct
    75481 gacaaagaat taatgtcaaa agatacaagg tataagagcc tgcaagagat gtttaacagt
    75541 gcgaatgaat ggagggtttc aaatgaaaga gttttataaa aaaagatttg ctcttacaga
    75601 tggaggagca agaaatttaa gtaaagcaac actggcttca tttttcgttt attgtataaa
    75661 catgcttcct gccatattac ttatgatttt tgctcaggaa gttttggaaa atatgggcaa
    75721 aagcaatggc ttttatatag tattctcagt tttgactttg atagcaatgt atattttgct
    75781 ttctatcgaa tacgataaat tatataacac aacctatcaa gaaagtgcag atttaagaat
    75841 aaggacagcg gagaatttat caaaattacc tctatcttac ttttctaaac atgacatttc
    75901 cgacatttca caaacaatca tggctgatat tgaaggcata gagcatgcaa tgagccactc
    75961 aataccaaag gtgggcggca tggtactgtt tttcccatta atatctgtaa tgatgctagc
    76021 gggcaatgtc aagatgggtt tagctgtaat tattccatct attttaagct ttatatttat
    76081 acctttatct aaaaaatatc aggttaatgg acagaataga tattatgatg tcttaagaaa
    76141 aaactcagaa agctttcaag aaaatatcga aatgcaaatg gagattaaag catataattt
    76201 atcgaaggat attaaagatg acttatataa aaaaatggaa gatagtgaga gaatacactt
    76261 aaaggcggaa gtaactacaa ttttaacttt gtctatatct tcaatattta gctttatatc
    76321 tcttgctgtt gtgatatttg tcggcgtaaa tctaattatt aataaagaga taaattctct
    76381 ctaccttata ggatatttac tagctgctat gaagataaaa gactctttag atgcatctaa
    76441 agagggcttg atggaaatat tttatttatc gcccaaaata gaaagattaa aagaaattca
    76501 aaatcaagat ttacaagaag gcgatgacta tagcttaaaa aaatttgata ttgatctaaa
    76561 agatgttgag tttgcctaca ataaagacgc aaaagtttta aatggtgtaa gttttaaagc
    76621 taagcaggga gaggtcactg ctttggtagg tgcaagtggc tgcggtaaaa caactatctt
    76681 gaaacttata tcaagacttt atgattatga caagggacaa atcttaatcg atggcaaaga
    76741 tataaaagaa atatcaacag aatctctttt tgataaggtc tctatagttt tccaagatgt
    76801 ggttctcttt aatcaaagcg ttatggaaaa tattagaatc ggtaagcaag atgcaagtga
    76861 cgaagaggtt aaaagagcag caaaacttgc aaattgcaca gattttatag aaaaaatgga
    76921 taaaggtttc gatacagtta ttggtgaaaa cggagctgag ctatcaggag gagaaagaca
    76981 aagattatca atagccagag ccttcttaaa agatgcgccg atattgatct tagatgagat
    77041 aacagcaagc cttgatgtta acaacgagaa aaagattcaa gagtctttaa ataatttagt
    77101 taaagataaa actgttgtaa tcatttcaca tagaatgaaa tccatagaaa atgcagacaa
    77161 gatagtagtt cttcaaaacg gaagagtaga aagcgaaggt aagcatgaag agcttttaca
    77221 aaaatcaaaa atttacaaaa atttaataga aaagacaaaa atggcagaag aatttattta
    77281 ttaggaggac tacaatggat aataaaaaat taaaagtaaa agatttagta agtatcggtg
    77341 tttttggcgt aatttatttt gccttcatgt ttggagttgg tatgatgggc ttgattccaa
    77401 tattgttctt aatatacccg acagtattag ccatagttgc aggaactgtt gttatgttat
    77461 ttatggctaa ggttcaaaag ccatgggcac tatttatatt tggtatgata tcaccacttg
    77521 tgatgtttgc agctggtcat acctacgtag ttgtggtttt atcacttata gtaatgataa
    77581 tagcagaatt aattagaaag attggtaatt ataattcatt taaatacaat atgctttctt
    77641 atgcaatctt cagcacatgg atatgtagct ctttaatgca aatgctttta gcaaaagaaa
    77701 aatatatgga gtggtctttg atgacgatgg gaaaagatta tgttgatgta ttagaaaagt
    77761 taataactta tcctcacatg gctttaatag ccttaggtgc tttcttagga ggaattcttg
    77821 gagcatatat aggcaaggct ctattgaaaa aacacttttc aaatggatta tattgtgtgg
    77881 gatactttac tccttgccta attttatggt gttatctgaa ttaaacccta tagttaagat
    77941 gtttttgagt atacctattg ttattagaat gtttatttta ccatttatgg cagcaagctt
    78001 tatgataaag acctcggatg taggcgcaat aatttcatcg atggataagc ttaagatttc
    78061 aaagaatgta tccataccta ttgcggttat gtttagattc ttcccatctt ttaaggagga
    78121 gaagaaaaac atcaaaatgg ctatgagagt aagagggata aattttaaaa acccagtcaa
    78181 atatcttgaa tatgtttctg tgccactact cattatatca tctaatatat cagatgacat
    78241 tgcaaaagcg gcagaaacaa aggcaataga aaatccaatt gccaagacca gatacattcg
    78301 cgtaaagata cagctaattg attttgttta tgttttagcg gttgctggac ttattgtggg
    78361 aggcttaata tggttgaaat aaaaaattta agtcttgatt atggtgaaga gcatatatta
    78421 gatgatatat cactatccat agccgaggga gagtgcgtgc tatttacagg aaaaagtgga
    78481 agtggtaagt catctttaat aaattcaatc aatggactag ctgtaaggta tgataacgca
    78541 aagacaaagg gcgaaataat tattgatggt aagaatataa aaaatttgga actttatcaa
    78601 atctcaatgc ttgtttcaac tgtttttcaa aatcctaaga catatttttt taatgtcaat
    78661 acgacattag aattattatt ttatttggaa aatatcggtc ttgcaagaga agagatggac
    78721 aggcgtttga aggatatact tgagatattc ccgataaaaa atcttttgaa cagaaatata
    78781 tttaatctat ccggcggtga aaaacaaatt ctttgcattg cagcttctta tatagcaggt
    78841 acaaagatta tagttatgga tgagtcttca tcgaatttag atattaaaag cataagtgtt
    78901 ttggcaaaga tgctaaagat attaaaagag aaaggcataa gcataattgt tgcagagcat
    78961 agaatttatt atttgatgga catagttgac cgtgtatttt taatagataa aggaaagctt
    79021 aaaaaaactt atactagaag tgaattttta aagctagata aaaatgaatt aaatgcttta
    79081 agtttaagag ataaagaatt aagtaaatta aaagttcctt atttaaaaga aggtggagag
    79141 tatcagataa aaaatcttag ctacaaattt actgatgatg agtgtttaag cttaaaagat
    79201 atttcgttca agcttgggaa aatttatggc ataataggat ccaacggacg aggaaaatca
    79261 acgcttttaa gatgtttaat aggtcttgag aaaaaatcaa aagaagaaat ttattttaag
    79321 ggagagaagc tatctaaaaa agaaagactc aaaaactctt cacttgttat gcaagatgta
    79381 aatcatcaat tattcacaga tgaagtattc aacgagctta gattaggagt aaagaatttt
    79441 gatgaagaaa aggcgaaaat cattttaaaa gatttaggcc tggacgaatt tattgaaagg
    79501 catccgatga gtttatcagg agggcaaaag caaaggcttg caatagcatc tgttatgtgc
    79561 aagacttctc catttatctt ttttgacgaa ccttcaagtg gtatagatta ttccaatatg
    79621 ataaaaatat ctgaactgat taataagtat aaaaccatgg ataaaataat ttttattgtt
    79681 tcccatgata tagaattttt aaatgaagtg gcagatgaaa tttttgaatt gtaaaataga
    79741 gtctgttaaa catgtctata gaactggtaa attgtctaaa aatttaaaag atactaacac
    79801 atattgatat ttattagaaa attaacttca ggatttttac agtatttata aactttataa
    79861 tatgtattta tagtattaat aatttccata tctttaggga aattatttat ttacttacca
    79921 taattaaaga gatgagagat aaatatcggc agtcttcgga ctgcctttat ttttttactt
    79981 aatttaatgc agtaaatcat acgattgaaa ggaatctgcg ttatatgcta taattaggta
    80041 gttaatctat acatttagaa aggtaaaata tagaattgga gaatgatatg ggattttcat
    80101 ataataaatt gtaaccaccc aataacgaag tctattgaaa aatctccaga ttagtgaact
    80161 cacggatagt tcctaatctg gagatttctt atttgcactt ttcttgtaca actttagtcc
    80221 atggtaaata agcctctaaa acctctttgt ttacgagagt ttcctcgttt ggaagacatt
    80281 ctagaagata ggatagatat ttctcgctat ttataatgga ttgaaataag atatgaacaa
    80341 atcgattagg aaaggaaaat tgatttatag aaatatttta gcagtcgatg cgtactgtta
    80401 tagattcaac gcactataat tgatgacgtt tagctgtttc caacaaactc ataataatag
    80461 ctcttgcttt agctccttca aaactttgag aaaataacca ccctcgcttt tttaaactga
    80521 gcttaggcta aaagagtcca ctggactctt ttactccgtc ccataaccaa tgatttaatg
    80581 gcgcattcag ctagattatt ggaaaggacc agatgtccgt ctttcaaaat agtcttaaag
    80641 gtttctttat acttgaggct gtattcaatt gcccttccta gttttgaacc cgataaaact
    80701 gactgacgcc ggcaccaagc aaagaaatct tccattaggt tggagctctt cttgacgttt
    80761 ctgtagtcgt tcatcagctg gcaaagcctc ccagtctctt tccaagaaaa ataactgatc
    80821 acaataagct aaacctttag ctcctaagga tgatttatcc gcttgcttgg gggtcgcttc
    80881 aaaaaacttc cttctcacat gcgcccaaca tccaacaagt gcagcttctt ccagttgacg
    80941 ataagcttct agcggttcgc agtttaccaa gcttagcgtc gccttgctcc taaaccttgg
    81001 actgctatcg cataggcaga actagaggac taaagtccta agttactgcc gcaacatatc
    81061 acaatgcaca tagccagaat aatctcctag gaattcttgt actactgaac cacttcgaca
    81121 ctgatcatgg tggtaaagcg taatcccttg tttctctgat ttacctgaca aaaaagtcca
    81181 atagtaagtc agctgactat cactttctaa gacccgataa gaggtttcat ctgcatgaag
    81241 aagaggttgt tctaacaact tttctcgtaa aaggttataa agggactcta aatagtattg
    81301 actcgccttg atatgccaat tagcaatttc cttacgtgtg attggtaaac ccatcctagc
    81361 ccaatcttct tcttggcgat aattaggtac cttcagatta aacttctgat ggatggtgtg
    81421 agcgataata gaagctgagt caatagtctc gttataaagg ggctttagga ataggagctt
    81481 tcacaatttt atcactcgga tttttatcac tgcatgcttg gcatttgtaa gcgtgttgga
    81541 tatgatctat gcgttttaat tgcgcaggaa taaagactaa ttcttgtcgt tgaagggttg
    81601 ctccaatctc ttttagatct ccctgacaat cagagcaaat gctctcttct acttgatgat
    81661 gaacttcttc tgaatcaaat tgggcaagaa gagcttggcg tttcccttta gatttcttac
    81721 gtttgtaggt aatttcctct gtttcaactg ggaacatctc catctttctc agatggagac
    81781 tcttcctcaa aaaggttgag ttgtccagag gggcaaacac ttttctcaga ggattttcca
    81841 tagagctttt gagtcagata agccacttgt tcacgaagaa gggcaagtgc attggtgaga
    81901 ctatcaattg tagcactctg ttgttgaatg attttcaatc ttcttccatg ggcttcccct
    81961 ccttgttttc tacctttatt atactaaaaa gaaagtcctc atttcaatag aaatcacgac
    82021 tttctgatgg atttattttt ggagtgatag aaaagtcctt cataagccag tctacttgtt
    82081 cagatgtgag agctttgaca tccttttctg tactgggcca agtcagtctg ccgttcccaa
    82141 agcgtttata tagtagccaa aatccttgac catcccagta aagggcttta aagcggtatt
    82201 tacgtccacc acaaaagaga aaaacttgac ctgagaaagg atctaattca aagtgggttt
    82261 taaccagata agccagtgaa tcaatgcctt gcctcatatc cgttttccca catacgagat
    82321 agacctgccc taggctagat agatgaattg tcatagagca acaccttatc caaaagctgt
    82381 tctaccattt cgagattgag agattgaaaa aaacttactt caagcttgcc aatacgaatt
    82441 ttaagcagaa tatcatttct ctttttagaa tcaaaaggac gagattgtgg aatctctaca
    82501 ggaacaatag gttgtggcat taaaatatcc tccaatagtt ttactttact aatagtatac
    82561 aggaggaact ccatgaatga tagatacctt gttatgacgc gattactata ttagaaagtt
    82621 ggctctctaa ttaaattaat tctcattata tatatcaaaa gaccgcagct tgaaaactac
    82681 ggtctaattt tttgtccaaa tgtaaaccac ttggaactat tattcaattt attcttttta
    82741 gtaaatgttc ccgttttaat cccagttaca gtttttaatc ctctgtaacc gttgatttta
    82801 caaagctttt aatttttttg cgattattcc cactcaactg ttgcaggtgg tttacttgta
    82861 atatcgtaga cgatacggtt aacatgatcc acttcattta cgatacgtac tgagattttt
    82921 tgaagtactt cccatggaat tttggcaaaa tcagcagtca taccatcgat agaagtgata
    82981 gcacggattg caatcgtgta gtcatatgta cgaccgtcac ccataacacc gactgaacga
    83041 acgcctgtgt taacagtgaa gtattgccaa atatcgcggt caagtccagc tttagcgatt
    83101 tcttcacgaa gaatagcgtc tgattcacga acggtttcaa gtttctcttc agtgatttca
    83161 cccatgacac ggatagcaag tcctggtcct gggaatggtt ggcgccatac gatatggtct
    83221 ggcataccaa gctctgtacc aagagcacga acttcatcct tgtaaagagt attgagtggt
    83281 tcaatcaatt caaactgcat atcttctgga agaccaccca cgttgtggtg tgacttgata
    83341 gtttgagctg tatccgtacc agactcgata acatctgtat ataaagtacc ttgagcaagg
    83401 aatttcacat ctttgagctt gcttgcttcg tcatcgaata catagacaaa ctcgttaccg
    83461 atgattttac gtttttgttc aggatcagaa acgccagcaa gtttgtcaag gaaacgttta
    83521 gcagcgtctg ctttgacgat attcaaacca aacttaccac cgagcatgtc cataacttga
    83581 tcagcttcgc ctttacgaag aagaccgtgg tctacgaaga tacagatcaa ttgatcgcca
    83641 atcgcttttt ggagaagaac cccaacgaca gatgagtcaa caccacctga tagaccaaga
    83701 aggacacgtt tatcaccgac ggtttcacga atttttttga tctgcatgtc aatgaaatta
    83761 tccattgacc agtcaccttt agccttacaa atgttaaggg caaagttacg aaggatatca
    83821 tttccgtata cagaatgacg aacttctggg tggaattgga taccgtaaat gtgtttatct
    83881 gggttttcga tggctgcgta tgggcagtca gctgatgtac ctgtacgaac aaagtcagca
    83941 ggaatctcag taaccgcatc accatggctc atcaaaacag tctgttcatc aggtgttgat
    84001 tcaaaaagcg ctgatggtgt gtgagttagg gttgattgac cgtattcacg atttccagca
    84061 tcacctgcag gaacaacttt tcctccaagt ttatgggtca ataactgcat accataacag
    84121 attcccaaaa ttggaattcc gagttcgaag atttctgggt caatatcaaa tgaaccatct
    84181 tcatatacag aatttggacc acctgataga ataattccta caggattgac ttcacgaact
    84241 tcagcagctg aaattttatg gctttttagt tctgaaaaaa caccaatctc acggatacgg
    84301 cgtgaaatca gctggttgta ctggctacca tagtccaata cgatgatttt ttctacatct
    84361 tgcaaatcag ttgaaatgtt gctcatcttt ttcctttctc aaaagaaata tcttttctca
    84421 atattctatc acaaataagg gcgaattacc aactaaacaa ggcgaagttt gactttttct
    84481 agtttattgg ggtacaatag agaaaagata gaaatgaagt gaaaaatatg ctacctgctt
    84541 atatgaaaat ccatgatcag ataaaaaagg atattgacga gcaccgttgg gctattggtg
    84601 agaggcttcc cagtgaaaga gatttagctg agcagtttgc ggtcagtcgc atgaccctcc
    84661 gccaagccgt atctctatta gtcgaagaag gcgtcttaga gcgccgtgta ggaagcggca
    84721 cctttgtttc cagtactcga gtacaagaaa agatgcgagg gacaaccagt tttactgaaa
    84781 ttgtcaaatc ccaaggtaaa gttccctcta gccagctcat ttcctacaaa aaaaccattc
    84841 ccaatgagca agaagttgcc aagctaggaa tttttccaac ggacaatatt atccgaatgg
    84901 agcgggtccg ctatgccgac caagttcccc tagtttatga agttgcttct attcctgaaa
    84961 aattcattaa ggactttaaa aaagaagaaa tcacaagtca tttcttccaa accttgcaaa
    85021 aacatggcta tcgtatcggc aaatctcaac agaccatcta tgctcgcctt gctaaagaaa
    85081 agattgccca ctatttggaa gttgaaaaag gacatgctat tcttggattg acccaggttt
    85141 cctacctaga agatggtact gcttttgaat acgtaaaaag tcaatatgta ggcgaacgct
    85201 ttgaatttta tcttgaaaat aattagatta ccacgcaaaa actctctgtc acggacaaag
    85261 agtctttttt atttttctaa gaataaatct ttcaaagaaa tcaaagttac agcaaacaat
    85321 atcattgcca taccaagaaa atcaatggga taaaattgtt cattcattat taagaaggca
    85381 aagaaaatcg ccgatattgg ctcaattgaa gccaacaagc ttgacttgac cggtcctatc
    85441 agactggctc ctttaaggaa agctgtatag gcaaagacag tcccgataag gataatgcct
    85501 gcaaacgcaa ggagaaaatc aagactagtc gggatatcgg cctgtagaac ccctgtaaaa
    85561 ggaagggcga ccaaacctgc tatgaccatt cccacaccaa tgagcaagct gctcccccac
    85621 tttttaatca aggctatggg taaaatgata tacagagcat aagtcaaggc agaaaagaga
    85681 ccccagaaca gaccagcagg tgtcatggat aactggtcca actgcccatg tgttgcgatc
    85741 aggaaggttc ctccgatggc gaatatgatg gaaactatct ctcccagtgt cggtgccacc
    85801 ctatccttga tacagctata aattaaaatt ccgacaggac aaacatactg aagcaccgtc
    85861 gctgttcccg cattggtctc ctgaatagca gacagatagg cgaattggtt gagaaaaaga
    85921 ccaatcagag caaaaataag aagagacagc aaactctttc tatcctttaa aaagaccagt
    85981 attttatcct ttgcagtagc ataagccaag agcatgagaa ttccaccagc gattaaaaga
    86041 cgcaagttgg tcaagaccag agccgaaatt ccgtgtgcca ttaggtattg gccactcgtt
    86101 cctgacaacc cccaagcaat accagccaca actgttagta aagtcccttt taaactattt
    86161 gacatgtctc tccttactct tctttgcgaa tcaagttcat cacttgattg cggtctaata
    86221 tccattgagc tctctcgtcc ttttcatagg tacgattcga taggaaaata gtggcttctt
    86281 gcttctgacg attccacatg ataaaggtac ctgtatagcc cgtatggtct agccaatctc
    86341 cttccaaatt ccatgctaaa gaacgttcct tgtcatccaa aggagaaaaa ttttgattta
    86401 agtctcttgc aaaatcatct gctaaatagt gttctaaaaa gatttgtaaa tcctttatag
    86461 tcgaaaataa accagcactc ccagcatgtc tacccaggag acgagccttg ggatcatgca
    86521 ctatgcctgc ctctacacct ctaactgttg gaacagcaag ctcaactggc ccaaacttgg
    86581 tttccgtcat tccccaaggt ttccagactt gatcctttaa aatcacatcc aaatcttgat
    86641 taaaaattct ttccaaaata aagcccaaca gcaaaaaatg gacatccgaa taaagaaagg
    86701 ctggctgact tcgtctgttg agatgaaaca tcgcttcctt taattcaggg gctgttaaaa
    86761 gatcacgatt aggaataaaa ggatcaaggt ctgttgcatg agtcaagagc tggcgaatag
    86821 tgatgtctgg ataatcactc tcaggtaaaa aatctattac cagtctatca atatctaatt
    86881 gacctatttc ccacaagaag gtacaaactg tgccaacccc aacaaccttg ctgacactag
    86941 ctagatcata aactagtcct gcctcagtct gcaagccatg ctctgggtca ctctggccta
    87001 aatagaactc tgtccattga ttgtccttaa aatacgcaaa agaggctccg ggataaattc
    87061 ctgcctcgat ttgttcttct atttttttaa taatcttggt ccacttcata cttcttcaaa
    87121 ccacaattca acattatttc tatctttacc aaggaagaat ttttcagact taggaataaa
    87181 atattcagta gactcaaact tctggcgaag acttgctatg tctaattcat tgaccaagaa
    87241 cttgagcata gataagtccc aggtaaccgt attgtccaca gtcaaatcct gcccctgagc
    87301 tggaataaaa tcaagggatg ccccaatttc agatgattcc aagaaacttt cgatatcagt
    87361 tgggagatgt aattccatag aaatctcaaa tttacttaaa gaaattgatg ccaaatctgt
    87421 ttgaaattca ggcttttctc ctacttctac tagacttgct ctgtcatctt ccgcatgaat
    87481 caaaatcaaa tcatcttctg gtgagaaaat ttcaaaagcg tagccatttt gacctttata
    87541 taatcgatga atcgaatctg ttttagataa gattccttca atttctaagg gattttccac
    87601 cttgacaatc aatctagcta gtttttttct tccctctacc ttacgagtac gcatactggg
    87661 agcttcttct aaaaccagct tttcaagacc cgtttggtca cctagtgaca gaaaggccga
    87721 ttcttctaac aaggccttca ttccaagggt ttcaatataa aatgtttcat ttaattttct
    87781 attattagct tttaaagtag gaataatccg tacaatctga tttacattca taaattcctc
    87841 cgtcactttt tattttaaag gattttagaa ttttttacaa gatattatgc tcaaatttaa
    87901 cattatttag ctatttagta aagatagtct ttcaaggatt ttgacaaagc ctgataacca
    87961 gcaatactga ggtgcagtcc atcagttgta tattcttttt tgagttggcc tgcttggtct
    88021 gtcaaacaat caaatactgg cacaaattcc acctgcatat aggcagatgc aagctcttga
    88081 taggcttgat tccagttctg aattttttca ttcgagcgga tatagactgc ctgctggtac
    88141 tcctctccct cattgacagg caaaatggaa agcaatttaa tctctgtcaa tggataatcg
    88201 cgagcaacgg attgaatgat agcttcgaga ttattgagag cctcattcac aggaacatcc
    88261 tttccgatat catttgtccc aatcagaaga aaaattttat ctactgctcc accatataga
    88321 tgagcatcaa gattctctag taacagtcct gtctgatagc cacgaattcc tcgattgaca
    88381 atcgtctttg aagtcccaaa tagctcctgt agaggataat actcgacaat ggaatcccca
    88441 ataaaaagaa tgtttggttc tacaacagaa atgtgattta ggtgacgata cttagtttga
    88501 attttttctt gttcctttag gagccaattt tctaataact gtactgccac ttcattctcc
    88561 tttttctaac cagttttcca agacttgata aactcctcct tggctgttgg ctggtgctag
    88621 agcagtcgcc acagctttgg ctttctcatc agcattttcc atcgcatagg caattccagc
    88681 catttcaagc atttcaacat cattttcact atcaccaaaa gccatgattt cttgggattt
    88741 caagtcccag cgcttgagta attcctccaa gccccatgct ttatgaatcc cagcttggag
    88801 gatatcaatg caaccatagc cactggatac agctcggaca cggccatcaa agagagcatt
    88861 gatttcttcc aaaaccgaac tcaaacgttc ctcaccaaca accatgctca tcttgagcac
    88921 accaccaaag aggtcagatg ttaattcatc cacaaattgc atccgttggt agaatttttc
    88981 aatcatttct ggagtcataa aactttcaag atctgtaaaa atcgtacctt ccttgacaaa
    89041 atcacccttc atccccgtta caacaaactg gtcctgacac gctcgaccct tgaaatgagc
    89101 caaagccttg ttgacaatgg cgtcatccca tgtctgagcc tgaatcaatt cattgttttc
    89161 aaaaatacga gcgccattag caacaaccag aaccactcga tccaccaagg gactcagtag
    89221 ttgtctcatg cggtgaattt cattgcccgt cgcaatgaca aaacgaatgc ccctttgatc
    89281 caactgatct aaaatctttt ccaatcgtgg gagatcaagc tgacccctag catccagcaa
    89341 ggtcccatcc atatctgtcg caattacctt aatcatcatt tactttcctc tggattcaag
    89401 ctaataccac ttcaatccca catgttcatt catttcttta taggctgtat caattcgttc
    89461 cttagtcgct tcatctaact ggtcacgatg actgccaccc ctctataaaa tcttccaaaa
    89521 tataagtttg gtaatgatac aagggatatc cttctggtga aaaggttccc tttggtgttc
    89581 gattgaccca agtaggatga gctttagctg ttccgatagt tgtttttcca tccttcttct
    89641 tgatggtgac atccatgaga acaccacgtt cagtccactt agcattctct tcatctccca
    89701 tagattcaat ccgttgattg gaaatgaagt tccccattta atagataatg agtttcttat
    89761 ctccatcttt ttcaaccgtt ttagatggtt caacaacgtg aggatgccct ccaaagataa
    89821 tatccgctcc ccaatcgatc atcttgtgat aaagagcttt ttgttcttca gttggttcca
    89881 atcgatactc aacacccatc tgaggcatga taatggtgat atctgcttcc ttctctgccc
    89941 gttcgacttc agcctttatc ttatcttcgt ttaaatctga aagataacga ttatagtctt
    90001 cctgaaaaat atactgctca attccattga aaccatagga ataggctaac aatgcaacct
    90061 tgatagcatt cacttcctta atgaccagcg gagcctgatc acgtggttcg tgcgtataaa
    90121 ctccgattgg agtgattcca gctttctcaa taatatcggc cattgaaata actccctcaa
    90181 tttgcgaatc caaaatatga ttatgagcta aatccagcac atgataacct gcttccttaa
    90241 tagcatccat aacttcaaca ggagcattaa agagaagata acccgctaaa taatgatcct
    90301 tattaatggt tccttcaaaa tcaccaatag ctaaatctgc ttgcttgagc caaggagtca
    90361 catactcaaa attttcatga aagtcatagg taccgtcttc ttttttagct gaaaagaaaa
    90421 gtccatcgtg gtagagcaaa tccccgtggg ccataattct ggcagttttt tcctcttcct
    90481 actcctgaga cttttgctta gtcccctctt gagaaatagt atctcgtttt tgactagtca
    90541 agggattcct tggaagcttt caaacaacaa gaccaagccc attgataaac caactgctag
    90601 caagagtatc gccacaaatc ccttattgct ccacttgcga taactcctaa aaagtttacc
    90661 aagcccttca taaaacgaaa agctaaacca ccctgatttc gattttgtct tctttgtatc
    90721 ttcattctcc ctactttctt atgcaagcct tttcttttta ttatatcaca gataagtatt
    90781 tctttcacaa ttgaattgaa cttcccatct attttctata aatcctaaat gccataatgc
    90841 tttcaattct tgtcattttg tgatatcatg tagaggtaat gaaaggaaat gaactaatcc
    90901 acagtggctt attccaagta taccacttgg gctttggcag tagttaactg cactaaacat
    90961 aatataagga gagaaaatgt ctgcaataga acgtattaca aaagctgctc acttaattga
    91021 tatgaacgat attatccgtg aagggaatcc tactctacgc gcgattgctg aggaagtcac
    91081 tttcccccta tctgaccagg aaatcatcct aggcgaaaag atgatgcaat tccttaaaca
    91141 ttcccaagat cctgtcatgg ctgaaaaaat gggactccgc ggtggtgttg gactggctgc
    91201 tccccagtta gatatctcaa aacgcattat cgctgttttg gtacctaata ttgttgaaga
    91261 aggcgaaact ccacaggaag cctacgattt ggaaggcatt atgtacaatc caaaaatcgt
    91321 ctctcactct gttcaagatg ctgctcttgg cgaaggagaa ggttgcctgt ctgttgaccg
    91381 taacgtgcct ggctatgttg ttcgccatgc ccgcgttact gttgactact ttgacaaaga
    91441 tggagaaaaa caccgtatca aactcaaagg ctacaactcc attgttgttc agcatgaaat
    91501 tgaccacatt aacggtatca tgttttacga tcgcatcaat gaaaaagacc catttgcagt
    91561 taaagatggt ttactgattc ttgaataaag aaaatcccgt tgcaagacgg ggttttgtgt
    91621 tataatagag gcatgaaaac aaatgatatt gtctatggtg tccacgccgt taccgaagcc
    91681 ctccttgcaa atacaggaaa caaactctac ctccaagaag atctccgagg taagaatgtt
    91741 gagaaagtca aggaactagc tacagaaaag aaggtgtcca tttcttggac atcaaaaaaa
    91801 tctctctctg agatgactga aggtgctgtt catcaaggtt ttgttctacg agtgtctgaa
    91861 tttgcctata gcgagctaga ttacatcctt gcaaaaacac gccaagaaga aaatccactt
    91921 ctattgattc tagatggtct aaccgatccc cataatctgg gttctatctt gcgaacagcc
    91981 gatgcgacca atgtttcagg tgtcatcatt cccaagcacc gtgctgtcgg agtaactcct
    92041 gtcgttgcca aaacagccac aggtgctatt gaacacgttc caattgcccg agtgacaaac
    92101 ctcagtcaaa ccttagataa actcaaggat gaaggcttct ggacctttgg aacggatatg
    92161 aacggtactc cttgccacaa gtggaataca aaagggaaaa tcgccctcat catcggaaat
    92221 gaaggaaaag gcatctctag caacatcaaa aaacaggtcg atgaaatgat taccattccg
    92281 atgaatggac atgttcaaag cctcaatgcc agtgttgctg cagccattct catgtacgaa
    92341 gtttttctaa atagactata aaaaagtttc cagtcatctg attggaaact tttttatgat
    92401 taactatgtt ctgtgataaa cttgtaggct tcttgaccag cgatagctcc atctccaact
    92461 gctgttgtta cttggcgaag gtctttcaag cgaacatctc caactgcaaa gataccgtcg
    92521 actgcagtct tcatgtggct atctgtcaca atccagcctg cctgatcttg gatattcaat
    92581 tctttaacaa aatcgctaag agggtccaaa ccaacataga taaagacacc accgaaggct
    92641 tgctctgtca cttgacctgt tttcacattt tcaaaaacga cagattctac tctgttttca
    92701 cccttgattt ccttcactac agaatcccag ataaagctga ttttttcatt cgcaaaggcg
    92761 cgatcttgta aaaccttttg ggcacgaagt tggtcacgac ggtgaacaat ggtaacagtc
    92821 ttagcaaaac gagtcaagaa gagggcttct tcaacagctg aatctccacc accaactacc
    92881 aataaatctt ggtcacggaa gaaagcacca tcacacacag cacagtaaga aacaccacga
    92941 ctgttcagtt cttcttctcc aggcactccc aaaggacggt gtttagaacc agttgctacg
    93001 ataactgtac gtgtttcata tgtttggtca tcagtcatca ctttcttaaa atcaccatgg
    93061 tcttcgacat tttcaacata accataaatg tgctcaacac caagattttc aagtggttca
    93121 aacatctttt cagccaattc aggtccacta atattagcgt atcctgggta attttcgata
    93181 tcagatgtat tattcatctg accacctggc agaccacctt caatcaaagc tacttttaga
    93241 ttgcttcgag cagcatacaa ggccgcagtc atccctgcag gtccagcacc gataataata
    93301 gtatcgtaca tatagattcc ttctttcttg ttgtaactat ctttattcta actctttctt
    93361 gtcaatcacg caaggattat gccttgaaaa caagaattaa actcataacc gcaaaggata
    93421 atactgggac aaccaagact ccaatcataa tcatatcata gagatgggct tggcgagccc
    93481 tggctgtctt atcaactccc gacatggctc tcagaccaat ccaaatccct aaaaaaatca
    93541 gaacaaggat ggtggtcaag atcaaactct cgaaatataa agaaaatagt tgcagtagca
    93601 tgatttctct catttctatc ttttttaaag agtaaactca gctagtccaa ctaactgagt
    93661 tttcctttat ctattatatc aaatataagt ccgtttgtaa ctagcgaaga attcttttgt
    93721 ccgctcttct ttaggggtgt ggataatctc atccggagtt ccagactcga tgattttccc
    93781 cttatctaat aagagaattt tatccgcaac ttgggctaca aaggacatgt catgactgac
    93841 caaaatcatg gtctgacctg acttagcagc atctgcaata gacttttcta cttcaccgac
    93901 caattctggg tcaagggctg aagttggttc gtctaagagc aaaacatctg gtttcatagc
    93961 aagcgcacgc gctagggcaa cccgttgctt ctgtccacct gataaatggc gaggataatg
    94021 gttttcacgg tccgaaagcc caaccttagc caactcttcc ttggcaatct tagtcgcttc
    94081 ttggtcagat aatttcttga caacaaccaa gccttctttc acattatcaa gtgctgttcg
    94141 acgttcaaat aaattaaact gttggaaaac catagacaac ttacggcgta gggcaaggat
    94201 ttcttcttga gtgattttag aaaaatcaac tgaaaaacca tcaatctgaa tagagccact
    94261 gtcaggtgtt tcaagataat tgagactgcg aagaaaggtt gattttccag ctcctgaaga
    94321 accaatcaag gctacaactt cccctttttg aatatccaag ttcagatgat ccaagacagt
    94381 ctgtcctgaa aaggatttgc ttaaattcga aatcttaatc attaacgaag gtctcctttc
    94441 acatctgttt gcactgtatc aggtgcagaa atagccattt ttctctcgat gaaacgaccg
    94501 aggctttcaa ttccgatatt gactacccaa taaacaaggg caacagagat gaagcgttca
    94561 aaatagcgat aatcagctcc acctagaatc tgagcttggg caaagacttc cacaacaccc
    94621 gcactaaaag ctagagatgt tcccttggtc aaaccgatga gggaattaat caaggttgga
    94681 gtagctacca ccgctgcatt aggaataatc actcgtcgat aaacttgcgc tcgggtcata
    94741 cccagactgc gcgccgcctc aatctcacca ggattaactg agagaatggc tgcacgaatg
    94801 gtttcactag cataagctgc ctcattaaag gcaaaagcga caatcgcaaa agctgcagct
    94861 ggaatcgcat tgatattgag accagttccc cattgctgat tgagggcttt caaagccaaa
    94921 gggattccgt agtaggtcaa catgagttgc accaaaatcg gtgtcccttt taagaaacta
    94981 acaaagaagg cctgcaaggg atataaaatc ttgacacgat tgatcttcac aatggcaaaa
    95041 agaagcgcca aaaccaagcc aaaaagggca ccaccaattg tcaacataat tgttgttgga
    95101 agttgttgga caattctagg gattccatca aagaccgaac gtaggctaaa cagcttgcca
    95161 tccggaatca attgcatcaa gttttggtac caatctgatg ctaaaatcgt tgtaacattc
    95221 ataaaaacat cctcttctga taatgattca ttctaccatg cttctgccgt caatgaaatt
    95281 atttgctacg gtcagataca gactttgtct acctactagt ttatcatact ttgaaacagg
    95341 gaagttatat attttatcta tcaaagagat agataaaaac tatttcagtc ccagttcttc
    95401 ataagatttt cgataaccga tttgcttaac agttccattt tctactaaaa tgggccgttt
    95461 taacaacata ccgtcacttg ctagcaactc agccgcttct tggtttgaca aacttcctac
    95521 cttatctttt agccctaatt cacggtattt gataccactg gtgttgaaaa attgcttcaa
    95581 ttcaaatcct gaggtttcta gccaattcaa aatgacttct tggctaggtg tttcttccac
    95641 gatatggacg gctttatagt ccacacctaa ttgatttaat tcttgttttg cttttttaca
    95701 agttgaacat ttggggtatt cgataaattc taacatgtgc ttctccttct atttgtttat
    95761 atctttaaaa tctacgcctt catgctccaa gagccaagct ttcttttcca ctcctgcagc
    95821 atagcctgtc agacgcttgc ctgctcccaa cacacgatga caaggtacta ggatagacca
    95881 aggattgcgt cccactgctc caccaattgc ttgagcagaa gccacttgca ggtcttgagc
    95941 aatttgtcca taggtcactg tctgaccata aggaatgccc tgtaaatagt cccaaactct
    96001 cttttcaaaa ttcgttccga ttggcgccaa gagcaagttg gataaatcct gaggcttgcc
    96061 tttaaagtaa tcatctaagc aagcaataac tgggtctaaa ataggatgac taacaacttc
    96121 ttctatcgtt tcatctccta gtcccctctc aaaatgcttc tgctcctgaa cccaaattcc
    96181 atacaaataa tggtcatcag ctacaagtga tagaatacca attggtgagg agtagagtat
    96241 ttttacatac ttcttttgca ttatttcttt aatttttgat aggccaagcg ttcgccatct
    96301 actggcacct taccaacttg tttaaaacca agtttttcaa aaatatgttg cataaccttg
    96361 ttttcagcat gcgtatctga gcgaaaatca agataatcaa aaccttcaat caagccctct
    96421 aagaaggttt gagcaactcc ttttccctgc acatctgctg ccacagcaat acggtgaaag
    96481 actagatact ctgactctcc agcttgccag tttccctcat aaatagcttc ataggcctcc
    96541 tctggactct tggtcacagc agcataggct agcagttctc cctcttccaa ggctacgtag
    96601 gcttgccctg agatgatatc atcgataata acatctgcat ttggatagcc attttgccac
    96661 tggtcactac cagcatctgc taaacatttt ttggcatcct ccatcacctg catgatggca
    96721 tctacttcat ttggaaaagc taaacgaatt tccatctttt ttcctcattt ctgactagtt
    96781 tctcccatca tagcataatt taagtatttc tacaagcagt taaaacttga ctttgtgttt
    96841 ttgttatttt ataatctagt tatcaaaact atataaaaag gagttgaaaa tgaaaactac
    96901 cttttcctac ccaaaatggg cagaaattcc aaacattgac ctctatctgg accaggtttt
    96961 gctctatgtc aatcaggtct gcgcccctat ctctcctaat aaagacaagg gcctaacagc
    97021 atctatggtc aacaattatg tgaaaaatgg ttacctgaca aagcctgaca aaaaaaaata
    97081 ccaacgccaa cagattgccc gtttgattgc tatcacaacc ctcaagtctg tattttctat
    97141 tcaagaaata gcccagacac ttaatactct acaaactcaa gcaagttcag accaactcta
    97201 cgatgctttt gtggactaca tgaaccaagg aattgaccca gctaacccta ttatccaaac
    97261 cagctgccaa accgtcaaac tctatcatca aactctagac ttaatcgatc atactcaaga
    97321 ggaggtaatc caatgaacac tagtcttaaa ctcagcaaac aactcagttt tggagaggag
    97381 attgctaata gcgtgaccca tgctgtgggt gcagtcatca tgcttatctt gctgcctatt
    97441 tcatccatct atagttatga agcacacgga tttttatcct ctatcggcgt ttccattttc
    97501 gtcatcagtc tctttctcat gttcctatca tccaccattt atcactctat ggcctatggt
    97561 tcgacccaca aatatgtttt gcgaatcatt gaccattcta tgatttacgt tgccattgcc
    97621 ggctcataca cgcccgttgt cttgaccttg atgaataact ggtttggcta tctgattatt
    97681 gtcatccaat ggggaacgac catctttggt attctctata aaatctttgc taaaaaggtc
    97741 aatgagaaat ttagccttgc tctttacctg attatgggct ggttggttct ggctatcatt
    97801 cctgccatta tcagtcaaac gacacccgtt ttctggagtc tcatggtaac tggcggactc
    97861 tgttatacag ttggagctgg attttatgcc aagaaaaaac cttatttcca catgatttgg
    97921 catctcttta tcctagctgc gtccgcactt caatacatcg ctattgttta ttacatgtaa
    97981 aaaagttgag aaattcaatc tcaacttttt tctttacaca tattgataaa gtactggtgc
    98041 aagcgcacat catcagtcaa ttctggatga aaagaactta ccaacatatt tttttcttgg
    98101 gctgcaacaa tttgattgtt cactgttgct agaatttcta caccctcacc aacactactg
    98161 ataatcggac cacggataaa ggtcattgga atcttgccaa ctcccttaca ttctgcttcc
    98221 gtgtagaaac ttcctaattg gcgcccataa gcattacgct cgaccaccat atccatagtt
    98281 cctagatgac tctctttctg agaagtgatt tccttagcca gcaaaattaa gcccgcacag
    98341 gtcccaaaca ctggtaagcc agatagaatg gcttctcgga tgggaagtag catgttctgg
    98401 tcacgtaaga gcttgcccat ggttgtagac tcaccaccag gcaaaatcaa acccgacaag
    98461 tcactctgat cttgctgaaa atcatctaga tttctgagtt ctacactctc gacacctaat
    98521 tgatctagca cttttgcatg ttctgcaaag gccccttgca aggccaatat tccaattttc
    98581 atctattttc ctcgttcagc catgagaatt tggatttcat tttcattaat accaaccatg
    98641 gcttctccta aatcttcaga gatttgagct aggatttgag gattacggaa gttagtcaca
    98701 gccttaacaa tggcactcgc tcgtttaaca ggatctcctg acttgaaaat acctgaaccg
    98761 acaaagaccc cctctgcccc taattgcatc attaacgcag catctgctgg cgttgcaaca
    98821 cctccagcag cgaaatttac aactggcaat tttccatgtt catgaacata ttggaccaat
    98881 tctacaggga cttgcaaatc cttggcagca acataaagct cgtcctcacg taagttttga
    98941 atgcggcgaa tttcctgatt catcatacgc atatgacgaa cagcttggac gatatcccct
    99001 gtccctggtt ctcctttggt acgaatcatg gaagcacctt cagcgatacg acgcaaggct
    99061 tcacccaaat ccttagcacc acagacaaaa ggaacttgga attctttctt gtccacatgg
    99121 aaacggtcat cagctggaga tagaacttca ctctcgtcga tataatcaat ttcaatagcc
    99181 tctaaaatct gagcttcaac aaaatgcccg attctgacct tagccattac tggaatacta
    99241 accgcttctt ggatttcctt aatcatcttt gggtcgctca tgcgggaaac tcctccagct
    99301 gcacgaatat cagccggaat tcgttccaag gccatcacag ctgccgcacc agcagcttct
    99361 gcgatacgag cctgttcagg attctgcaca tccataataa caccaccctt gagcatctgt
    99421 gccaagtttt tatttagttc ataacgattt tcagtcattt gttttatcct catcatttgt
    99481 attggtagct accttttcat tttaagtcag aacagaatga agcacaagat aaaaaaacta
    99541 taattgtatg gggacagatt ggctaaaaac tatctgacct taacttaagg ccagatagct
    99601 cattcatttt tatttttcag ccgtaagggc agccattgtg atgtagttgt atggtttatt
    99661 gaagtgtggc aagaagaaga ggtctgtcaa tgccaattta tcaattgtca catgctcttg
    99721 gatagcaagt gagaacatgt ggattcccat gctaattgca atatcatgtg aaaccatttg
    99781 ggcaccaaga atttcacggc tatctttgtc aaagacaatc ttaattgcta cttcatggtt
    99841 gtcatgtttc atgaattctg gtttttgaag atcgttaaag cctgtttcag ttgcgttgta
    99901 accagcagct ttcgcttttt caagagtcaa accagttgaa accatgtgaa gaccgtagat
    99961 tgagatacca tttgaacctt gaacaccgat tccttccaat tcatgtccac aagcgttgta
   100021 ggcaccaacg ataccagtgc gaacagcatt tgaagcaaga gcgatatagc ttgtatcttt
   100081 acgagcattg tcataaacag tcgcacagtc accaacagcg taaacgcctg ggatagatgt
   100141 ttcttgtttc ttgtctacaa ggaaggcacc gttgcggaag agttcgatct taccatcagc
   100201 aagggctgtg tttggacgga aaccaactgc aaggataacc atatccacgt caaagctttc
   100261 tttgtcagta atcaagcgtt caactttacc atcaccttcg attgctttaa cagtttgacc
   100321 tagagccaag cggatgttgt gatcttccaa gttcttcgcc atcatttgtg tgaagtcttt
   100381 gtcatagtaa ccgttcaaga cagtatcaac gatatcaaca aggacaactt cttttccaag
   100441 acgttcaaag gcttcagcaa gttcaacacc gatgtaacca ccaccaacaa cggcgatacg
   100501 gtcgagatgt tggctcttgt cagaaagttt attgataact tcttcagcat tttggtacaa
   100561 tttcacgaat tgtacgtttt caagagttgc tttaaattcg cggtttcctt taacaatttc
   100621 aacaccttcg attggtggca agattggtgt agaacctgta gcgaaaatca atttctcgta
   100681 tgattctttg tgttcttttc cttcaacttc tgctgtaacc actttgttat catagtcgat
   100741 tgaaagaact ggtgaattca tataaacctt agcaccttta gcttctaatt tgtctttatc
   100801 agaatagaac aagccttcag caccgtcaat ttgttcacca atccaaagag ccattccaca
   100861 tcctaggaaa gagatgttag agttttggtc aaatacaaca atttcgttct catttccaaa
   100921 attatccaac atggtattga tacatgctgt accagcgtgg ttagcaccga ctacaacgat
   100981 tttactcata aaaaatttcc tgccttcatt ctaaatttac tttactagta taccatttac
   101041 cgttagcgtt tacaaggggg ggactattat ttcagcattt tttatcaaaa ataattcccc
   101101 atttatcctg ttttcaagcc tcatgaattt tatgagcata tttcttgact ttttccaaat
   101161 tttgtttgtg aaaattctaa ctttatggta ttataataac atgaaaataa aatgtaaggg
   101221 cttcaattta gatgattatt tgatattgca acttattttc tataagagaa aggagttggt
   101281 agcttgactc ttcgttcaca ttctgaacgg ctaatgggga ctactatcac tatttcatta
   101341 gtggatgagc aagccgatat ctttctccaa aaatcctttg acttgctcaa agagcttgaa
   101401 taccgcttca acgccaatag tcaagaatct gagttgatgg aaatcaatta tcaagcagga
   101461 atatcccccg tcacagttca tccagacctg tttgagctga tttcacttgg gttagagcat
   101521 agcctagcgc tctctagcca cctcaatatc agcattggtc ccttaattca aacctggcgt
   101581 atcggttttt cagatgccaa ggtcgcccag cctcaagaaa ttgaatcggt gctgcctcta
   101641 atcaatcctc atggtatcga gttagattct tctacttcta ctgtgttttt aaaacagaaa
   101701 ggaatgaaga tcgatctagg ttgtttagcc aaaggataca gtgcggataa ggttgcccaa
   101761 tttcttagga aagagggggt gacttctgcc ttgatcaatc tgggagggaa tatcctgacc
   101821 attggaaaaa atcaggcaag aggggataac ccatggcaaa tcgggattca agacccagcc
   101881 aatcctaggg gaaatcattt aatgaccatc cctgttgtca ataaatctgt cgtgacttca
   101941 ggcatttatg aacgtcacct gaccgtcgat ggacaagatt accatcacat ttttgacagt
   102001 caaacaggat atcctgttga aacggaacta gcgagtctaa caatcatctc tgataaatca
   102061 gtcgatggcg aaatctggac gactcgactc tttggagaaa gacctgcttc tatcctctgg
   102121 caagtcgaaa gtttggaggg catcgaagtc atcctcatcg ataaagaagg ccacctaagc
   102181 tgttcttcag gaattcctac tctatagaga caactgtttc aatggaattt taaaattgta
   102241 ttatgtaaaa agagaaagga aatatcatgt taaaacttat tgctattgtt ggaacaaatt
   102301 caaaacgttc tacaaaccgt caattgcttc aatacatgca aaaacacttt gctgacaaag
   102361 ctgaaattga acttgttgaa atcaagacca ttcctgtctt caacaaacca gctgacaagc
   102421 aagtacctgc tgaaatattg gaaattgctg ctaaaatcga agaggcagat ggcgttatta
   102481 tcggtactcc tgagtatgat cactctattc cagctgtttt gatgagcgct cttgcttggt
   102541 tgtcttatgg tatttaccca cttttgaaca aaccaatcat gattacaggt gcttcttacg
   102601 gtacgcttgg ttcatctcgt gcccaattgc aacttcgtca aatcttgaat gctcctgaaa
   102661 tcaaggcaaa tgttcttcca gatgaattct tgctcacaca ctctcttcaa gcatttaacc
   102721 caagtggcga cttggttgac cttgatgtta tcaagaaatt ggatgccatc tttgatgact
   102781 tccgtatctt cgtgaagatt actgagaaat tgcgcaatgc gcaagaattg cttcgcaaag
   102841 atgctgaaga ctttgactgg gaaaatttgt aagataggag accgaaagaa tgaaatttgt
   102901 tggacttgtt ggatcaaact acgatcaatc atataaccgc aaactcttgg aatttatccg
   102961 tcgcaatttc aaattcaaat ttgaattaga agtacttgaa atcgacgaag ttccaatgtt
   103021 taaccaagac gaaaaatggg acgaaagctt ccaattgcgt ttcttgtata acaagattac
   103081 acgtgctgat ggtgtcatta tcgccactcc tgagcacaac cacactatct cagcttcact
   103141 caaatctgta cttgaatggc tttcatacga agttcatcca tttgaaaaca agcctgttat
   103201 gattgtgggt gcatcatact atgaccaagg aacatcacgt gctcaagttc accttcgtaa
   103261 aatccttgat gctccaggtg ttaatgccta cacgcttcca ggtaacgaat tccttcttgg
   103321 taaagctaag gaagcttttg ataacaacgg aaatatcacc aacgaaggca ctgttaaatt
   103381 ccttgaaact tgcttagata actttgttaa atacgtagga gtcgtttcga aattgaaaaa
   103441 accaaaacca atcgaatcag aagacttgga ttgtggaaaa ccaatcgcta caaccatcac
   103501 agaagttgac cctgacgatc cagaatgggt agaaaaagtt gcagcaatca ctggtgctgt
   103561 ttctggtgat acctatgtca aattggacca cggtatccta acagttaacc aaattgatat
   103621 gttcttgaaa gctatgccat ttgaattgac atacgctgac gacaacaacc aattcctcta
   103681 ctacaacaac gctcaccaag atccagacac tatgttcgct aaacgtgtac cacctcaatc
   103741 aggtagccgt atgtcgactg ttcatggttc tcttccacca gcacgtatga agaacgtaga
   103801 gtgggttatc ggaacacttc gcaacggaaa ccaagaatac gtccgtacga tcgttccagg
   103861 ttctcctgca ggtgttatca acactcacaa ctaccaagca atgtactatc ctgatggatc
   103921 atacgctggt atcaatgaaa tcgtctttaa cttccaacca tggcttgact ggtacctaaa
   103981 agagactggt caacgtttgg tgggtggtag cggaccattt gctcctgctg ccggaggtca
   104041 tggagacgcc gatgctactt ctggcgcttc tgattcaggg gatgctggag gccacggtgg
   104101 tgacgcagac gctacagccg gtgcaagtta
//
LOCUS       DAVBEO010000002        84741 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 009
            SAMEA1678075-rid20185393.denovo.002, whole genome shotgun sequence.
ACCESSION   DAVBEO010000002 DAVBEO010000000
VERSION     DAVBEO010000002.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678075
            Sequence Read Archive: ERR226392
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 84741)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 84741)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980207.1
            Genome Coverage       :: 150x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:50:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 72 of 147
            Pseudo Genes (incomplete)         :: 72 of 147
            Pseudo Genes (internal stop)      :: 42 of 147
            Pseudo Genes (multiple problems)  :: 32 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..84741
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678075-rid20185393.denovo.002"
                     /strain="KS 009"
                     /db_xref="taxon:1313"
     gene            <1..722
                     /locus_tag="VQ543_000113"
     CDS             <1..722
                     /locus_tag="VQ543_000113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HET2610919.1"
                     /translation="KKDAHGIALKLLSDPNREQFQHDNRQVELKILARHIHRLKKKQS
                     DWKVQYTRCLDIIFPELDKIVEKHSEYTYQLLTCYPNPQKRLEAGFDKLIEIKRLTAS
                     KIQDILSVAPRSIGTTSPAREFEIIKHYKRLIDKAETCVNDLMAEFNSVITTVTGIGN
                     RLEAVILAEIRNIHAFDNPAQLQAFAGLDSSIYQSGQIDLAGRMIKRGSPHLRWALIQ
                     AAKACPRFSPAFKAYLKTKLE"
     gene            complement(1023..2912)
                     /locus_tag="VQ543_000114"
     CDS             complement(1023..2912)
                     /locus_tag="VQ543_000114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000750662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2207 domain-containing protein"
                     /protein_id="HET2610920.1"
                     /translation="MKKTFFLLVLGLFCLLPLSVFAIDFKINSYQGDLYIHADNTAEF
                     RQKIVYQFEEDFKGQIVGLGRAGKMPSGFDIDPHPKVQAAKNGAELADVTSEVTEEAD
                     GYTVRVYNPGQEGDIVEVDLVWNLKNLLFLYDDIAELNWQPLTDSSESIEKFEFHVRG
                     DKGAEKLFFHTGKLFREGTIEKSNLDYTIRLDNLPAKRGVELHAYWPRTDFASARDQG
                     LKGNRLEEFNKIEDSIVREKDQSKQLVTWVLPSILSISLLLSVCFYFIYRRKTTPSVK
                     YAKNHRLYEPPMELEPMVLSEAVYSTSLEEVSPLVKGAGKFTFDQLIQATLLDVIDRG
                     NVSIISEGDAVGLRLVKEDGLSSFEKDCLNLAFSGKKEETLSNLFADYKVSDSLYRRA
                     KVSDEKRIQARGLQLKSSFEEVLNQMQEGVRKRVSFWGLPDYYRPLTGGEKALQVGMG
                     ALTILPLFIGFGLFLYSLDVHGYLYLPLPILGFLGLVLSVFYYWKLRLDNRDGVLNEA
                     GAEVYYLWTSFENMLREIARLDQAELESIVVWNRLLVYATLFGYADKVSHLMKVHQIQ
                     VENPDINLYVAYGWHSLFYHSSAQMSHYASVANTASTYSVSSGSGSSGGGFSGGGGGG
                     SIGAF"
     gene            3050..4615
                     /locus_tag="VQ543_000115"
     CDS             3050..4615
                     /locus_tag="VQ543_000115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HET2610921.1"
                     /translation="MRKIYLSIFTSLLLMLGLVNVAQADEYLRIGMEAAYAPFNWTQD
                     DDSNGAVKIDGTNQYANGYDVQIAKKIAKDLGKKPLVVKTKWEGLVPALTSGKIDMII
                     AGMSPTAERKQEIAFSSSYYTSEPVLLVKKDSAYASAKSLDDFNGAKITSQQGVYLYD
                     LIAQIPGAKKETAMGDFAQMRQALEAGVIDAYVSERPEALTAEAANSKFKMIQVEPGF
                     KTGEEDTAIAIGLRKNDNRISQINASIETISKDDQVALMDRMIKEQPAEATTTEETSS
                     SFFSQVAKILSENWQQLLRGAGITLLISIVGTIIGLIIGLAIGVFRTAPLSENKAIYG
                     LQKLVGWVLNVYIEIFRGTPMIVQSMVIYYGTAQAFGINLDRTLAAIFIVSINTGAYM
                     TEIVRGGILAVDKGQFEAATALGMTHNQTMCKIVLPQVVRNILPATGNEFVINIKDTS
                     VLNVISVVELYFSGNTVATQTYQYFQTFTIIAVIYFVLTFTVTRILRFIERRMDMDTY
                     TTGANQMQTEDLK"
     gene            4615..5379
                     /locus_tag="VQ543_000116"
     CDS             4615..5379
                     /locus_tag="VQ543_000116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HET2610922.1"
                     /translation="MTQAILEIKHLKKSYGQNEVLKDISLTVHKGEVISIIGSSGSGK
                     STFLRSINLLETPTDGQILYHGQNVLEKGYDLTQYREKLGMVFQSFNLFENLNVLENT
                     IVAQTTVLKRERTEAEEIAKENLEKVGMGERYWQARPKQLSGGQKQRVAIARALSMNP
                     DAILFDEPTSALDPEMVGEVLKIMQDLAQEGLTMIVVTHEMEFARDVSHRVIFMDKGV
                     IAEEGKPEDLFTNPKEDRTKEFLQRYLILNENQRAN"
     gene            complement(5578..5793)
                     /locus_tag="VQ543_000117"
     CDS             complement(5578..5793)
                     /locus_tag="VQ543_000117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002893653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2610923.1"
                     /translation="MAKSNFEKVESVVGWVRDKKITGYRISKETNAREMSIIALAQGR
                     AKVKNISFETALGLIDFYEKNHEKFED"
     gene            complement(6664..7914)
                     /gene="ilvA"
                     /locus_tag="VQ543_000118"
     CDS             complement(6664..7914)
                     /gene="ilvA"
                     /locus_tag="VQ543_000118"
                     /EC_number="4.3.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine ammonia-lyase IlvA"
                     /protein_id="HET2610924.1"
                     /translation="MLSSKDIIKAHKVLNGVVVNTPLDYDHYLSEKYGAKIYLKKENA
                     QRVRSFKIRGAYYAISQLSKEERERGVVCASAGNHAQGVAYTCNEMKIPATIFMPITT
                     PQQKIGQVRFFGGDFVTIKLVGDTFDASAKAAQEFTVSENRTFIDPFDDAHVQAGQGT
                     VAYEILEEARKESIDFDAVLVPVGGGGLIAGVSTYIKETSPEIEVIGVEANGARSMKA
                     AFEAGGPVKLKEIDKFADGIAVQKVGQLTYEATRQHIQTLVGVDEGLISETLIDLYSK
                     QGIVAEPAGAASIASLEVLAEYIKGKTICCIISGGNNDINRMPEMEERALIYDGIKHY
                     FVVNFPQRPGALREFVNDILGPNDDITRFEYIKRASKGTGPVLIGIALADKHDYAGLI
                     RRMEGFDPAYINLNGNETLYNMLV"
     gene            complement(7964..8320)
                     /locus_tag="VQ543_000119"
     CDS             complement(7964..8320)
                     /locus_tag="VQ543_000119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001027901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketol-acid reductoisomerase"
                     /protein_id="HET2610925.1"
                     /translation="MNITNLFSIKTGCDETDRQLQKLFFQLDLQLGELTDQLRKLDSN
                     FVPRSQFVDTLDLNDVEYKEILNYFIFHRNDSEESLVEWLYDWISTNRYELPKEFSIR
                     MAHKYHESVTEVFGDE"
     gene            complement(8558..8794)
                     /locus_tag="VQ543_000120"
     CDS             complement(8558..8794)
                     /locus_tag="VQ543_000120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2610926.1"
                     /translation="MLADQNKADWSYDENAVINIYDDANFEDGRLHMTFEQFFKLAQI
                     AREEGLEIHSPFERAGATKSARYIAKWILRNKKH"
     gene            complement(8901..9923)
                     /gene="ilvC"
                     /locus_tag="VQ543_000121"
     CDS             complement(8901..9923)
                     /gene="ilvC"
                     /locus_tag="VQ543_000121"
                     /EC_number="1.1.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketol-acid reductoisomerase"
                     /protein_id="HET2610927.1"
                     /translation="MTVQMEYEKDVKVAALDGKKIAVIGYGSQGHAHAQNLRDSGRDV
                     IIGVRPGKSFDKAKEDGFDTYTVVEATKLADVIMILAPDEIQQELYEAEIAPNLEAGN
                     AVGFAHGFNIHFEFIKVPADVDVFMCAPKGPGHLVRRTYEEGFGVPALYAVYQDATGN
                     AKNIAMDWCKGVGAARVGLLETTYKEETEEDLFGEQAVLCGGLTALIEAGFEVLTEAG
                     YAPELAYFEVLHEMKLIVDLIYEGGFKKMRQSISNTAEYGDYVSGPRVITEQVKENMK
                     AVLADIQNGKFANDFVNDYKAGRPKLTAYREQAANLEIEKVGAELRKAMPFVGKNDDD
                     AFKIYN"
     gene            complement(9989..10465)
                     /gene="ilvN"
                     /locus_tag="VQ543_000122"
     CDS             complement(9989..10465)
                     /gene="ilvN"
                     /locus_tag="VQ543_000122"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002927678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase small subunit"
                     /protein_id="HET2610928.1"
                     /translation="MRRMLTAKLQNRSGVLNRFTGVLSRRQVNIESISVGATEDPNVS
                     RITIIIDVASHDEVEQIIKQLNRQIDVIRIRDITDKPHLEREVILVKMSAPAEKRAEI
                     LAIIQPFRATVVDVAPSSITIQMTGNAEKSEALLRVIRPYGIRNIARTGATGFTRD"
     gene            complement(10458..12158)
                     /locus_tag="VQ543_000123"
     CDS             complement(10458..12158)
                     /locus_tag="VQ543_000123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000411733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase large subunit"
                     /protein_id="HET2610929.1"
                     /translation="MEKISLESPKTGSDLVLETLRDLGVDTIFGYPGGAVLPFYDAIY
                     NFKGIRHILGRHEQGCLHEAEGYAKSTGKLGVAVVTSGPGATNAITGIADAMSDSVPL
                     LVFTGQVARAGIGKDAFQEADIVGITMPITKYNYQVRETADIPRIITEAVHIATTGRP
                     GPVVIDLPKDISALETDFIYSPEVNLPSYQPTLEPNDMQIKKILKQLSKAKKPVLLAG
                     GGISYAEAATELNEFAERYQIPVVTSLLGQGTIATSHPLFLGMGGMHGSFAANIAMTE
                     ADFMISIGSRFDDRLTGNPKTFAKNAKVAHIDIDPAEIGKIISADIPVVGDAKKALQM
                     LLAEPTVHNNTEKWIEKVTKDKNRVRSYDKKERVVQPQAVIERIGELTNGDAIVVTDV
                     GQHQMWTAQYYPYQNERQLVTSGGLGTMGFGIPAAIGAKIANPDKEVVLFVGDGGFQM
                     TNQELAILNIYKVPIKVVMLNNHSLGMVRQWQESFYEGRTSESVFDTLPDFQLMAQAY
                     GIKNYKFDNPETLAQDLEVITEDVPMLIEVDISRKEQVLPMVPAGKSNHEMLGVQFHA
                     "
     gene            complement(12359..14026)
                     /locus_tag="VQ543_000124"
     CDS             complement(12359..14026)
                     /locus_tag="VQ543_000124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000036655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DAK2 domain-containing protein"
                     /protein_id="HET2610930.1"
                     /translation="MSKITTSLFQEMVQAASTRLNKQAEYVNSLNVFPVPDGDTGTNM
                     GMTIENGAKEVADKPASTVGEVASILAKGLLMGARGNSGVITSQLFRGFSQAIKDKDE
                     LTGQDLALAFQSGVEVAYKAVMKPVEGTILTVSRGAAIGAKKKAEQTDDTVEVMRAAL
                     EGAKTALAKTPDMLPVLKEVGVVDSGGQGLVFIYEGFLSALTGEYIASEDFVATPANM
                     SEMINVEHHKSVAGHVATEDITFGYCTEIMVALKQGPTYAKDFDYDEFRNYLDELGDS
                     LLVVNDDEIVKVHVHTEDPGLVMQEGLKYGSLVKVKVDNMRNQHEAQVEKEATQVIKS
                     AEEKEYALIAVVAGKGLADIFCSQGVDYVIEGGQTMNPSTEDFIKAVEQVNARNIIFL
                     PNNKNIFMAAQSAAEVLEQPAVVVEARTLPQGMTSLLAFDPSKSIEENQERMTAALSD
                     VVSGSVTTAVRDTTIDGLEIHENDNLGMVDGKILVSNPDMHQTLTETLKHMLDEDSEI
                     VTFYVGEDGSEELANEIAQEIVEEFEDVEVEIHQGQQPVYPYLFSVE"
     gene            complement(14029..14394)
                     /locus_tag="VQ543_000125"
     CDS             complement(14029..14394)
                     /locus_tag="VQ543_000125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HET2610931.1"
                     /translation="MTVKINTKDGQIELTDEVIATVVGGAATEIFGVVGMASKNALKD
                     NFQALLGKENYSKGVVVKAAEDGSIAVDVYTVLSYGTKISEVSKNIQERVAFSLENQL
                     GITAQTVNVYIQNIKVVGE"
     gene            complement(14551..14739)
                     /locus_tag="VQ543_000126"
     CDS             complement(14551..14739)
                     /locus_tag="VQ543_000126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008536053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L28"
                     /protein_id="HET2610932.1"
                     /translation="MAKVCYFTGRKTVSGNNRSHAMNQTKRAVKPNLQKVTVLIDGKP
                     KKVWASARALKSGKVERV"
     gene            complement(14855..15031)
                     /locus_tag="VQ543_000127"
     CDS             complement(14855..15031)
                     /locus_tag="VQ543_000127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001858191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase family 8"
                     /protein_id="HET2610933.1"
                     /translation="MDSDIVVRKSIDELWDLDLTAIPLAAVRDDFYTHNFNSGVLLIN
                     DGMWRAENVTQDLI"
     gene            complement(15142..15291)
                     /locus_tag="VQ543_000128"
     CDS             complement(15142..15291)
                     /locus_tag="VQ543_000128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase family 8"
                     /protein_id="HET2610934.1"
                     /translation="MDKVETTIKSLCVHHYNLKFYVFNDDLPREWFQLMEKRLETLNS
                     EIVNV"
     gene            complement(15603..17147)
                     /locus_tag="VQ543_000129"
     CDS             complement(15603..17147)
                     /locus_tag="VQ543_000129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011681503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 3"
                     /protein_id="HET2610935.1"
                     /translation="MNIQEEIKKRRTFAIISHPDAGKTTITEQLLYFGGEIREAGTVK
                     GKKTGTFAKSDWMDIEKQRGISVTSSVMQFDYDGKRVNILDTPGHEDFSEDTYRTLMA
                     VDAAVMVVDSAKGIEAQTKKLFEVVKHRGIPVFTFMNKLDRDGREPLDLLQELEEILG
                     IASYPMNWPIGMGKAFEGLYDLYNQRLELYKGDERFASLEDGDKLFGSNPFYEQVKDD
                     IELLNEAGNEFSEEAILAGELTPVFFGSALTNFGVQTFLEIFLKFAPEPHGHKKTDGE
                     IVDPYDKDFSGFVFKIQANMDPRHRDRIAFVRIVSGEFERGMSVNLPRTGKGAKLSNV
                     TQFMAESRENVINAVAGDIIGVYDTGTYQVGDTLTVGKNKFEFEPLPTFTPEIFMKVS
                     AKNVMKQKSFHKGIEQLVQEGAVQLYKNYQTGEYMLGAVGQLQFEVFKHRMEGEYNAE
                     VVMNPMGKKTVRWIKPEDLDERMSSSRNILAKDRFDQPVFLFENDFALRWFADKYPDV
                     ELEEKM"
     gene            17360..17662
                     /gene="gatC"
                     /locus_tag="VQ543_000130"
     CDS             17360..17662
                     /gene="gatC"
                     /locus_tag="VQ543_000130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006147946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatC"
                     /protein_id="HET2610936.1"
                     /translation="MKITQEEVTHVANLSKLRFSEEETAAFATTLSKIVDMVELLGEV
                     DTTGVAPTTTMADRKTVLRPDVAEEGTDRDRLFKNVPEQDNYYIKVPAILDDGGDA"
     gene            17662..19128
                     /gene="gatA"
                     /locus_tag="VQ543_000131"
     CDS             17662..19128
                     /gene="gatA"
                     /locus_tag="VQ543_000131"
                     /EC_number="6.3.5.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatA"
                     /protein_id="HET2610937.1"
                     /translation="MTFNNKTIEELHNLLVSKEISATELTQATLENIKSREEALNSFV
                     TIAEEQALVQAKAIDEAGIDANNVLSGIPLAVKDNISTDGILTTAASKMLYNYEPIFD
                     ATAVANAKTKGMIVVGKTNMDEFAMGGSGETSHYGATKNAWDHSKVPGGSSSGSAAAV
                     ASGQVRLSLGSDTGGSIRQPAAFNGIVGLKPTYGTVSRFGLIAFGSSLDQIGPFAPTV
                     KENALLLNAIASEDTKDSTSAPVRIADFTSKIGQDIKGMKIALPKEYLGEGIDPEVKE
                     TILNAAKHFEKLGAIVEEVSLPHSKYGVAVYYIIASSEASSNLQRFDGIRYGYRAEDA
                     TNLDEIYVNSRSQGFGEEVKRRIMLGTFSLSSGYYDAYYKKAGQVRTLIIQDFEKVFA
                     DYDLILGPTAPSVAYDLDSLNHDPVAMYLADLLTIPVNLAGLPGISIPAGFSQGLPVG
                     LQLIGPKYSEETIYQAAAAFEATTDYHKQQPVIFGGDN"
     gene            19128..20570
                     /gene="gatB"
                     /locus_tag="VQ543_000132"
     CDS             19128..20570
                     /gene="gatB"
                     /locus_tag="VQ543_000132"
                     /EC_number="6.3.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002946582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatB"
                     /protein_id="HET2610938.1"
                     /translation="MNFETVIGLEVHVELNTNSKIFSPTSAHFGNDQNANTNVIDWSF
                     PGVLPVLNKGVVDAGIKAALALNMDLHKKMHFDRKNYFYPDNPKAYQISQFDEPIGYN
                     GWIEVELEDGTTKKIGIERAHLEEDAGKNTHGTDGYSYVDLNRQGVPLIEIVSEADMR
                     SPEEAYAYLTALKEVIQYAGISDVKMEEGSMRVDANISLRPYGQEKFGTKTELKNLNS
                     FSNVRKGLEYEVQRQAEILRSGGQIRQETRRYDEANKATILMRVKEGAADYRYFPEPD
                     LPLFEISDEWIEEMRTELPEFPKERRARYVSDLGLSDYDASQLTANKVTSDFFEKAVA
                     LGGDAKQVSNWLQGEVAQFLNAEGKTLEQIELTPENLVEMIAIIEDGTISSKIAKKVF
                     VHLAKNGGGAREYVEKAGMVQISDPAILIPIIHQVFADNEAAVADFKSGKRNADKAFT
                     GFLMKATKGQANPQVALKLLAQELAKLKEN"
     gene            20699..21259
                     /gene="efp"
                     /locus_tag="VQ543_000133"
     CDS             20699..21259
                     /gene="efp"
                     /locus_tag="VQ543_000133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P"
                     /protein_id="HET2610939.1"
                     /translation="MIEASKLKAGMTFETADGKLIRVLEASHHKPGKGNTIMRMKLRD
                     VRTGSTFDTSYRPEEKFEQAIIETVPAQYLYKMDDTAYFMNTETYDQYEIPVVNVENE
                     LLYILENSDVKIQFYGTEVIGVTVPTTVELTVAETQPSIKGATVTGSGKPATMETGLV
                     VNVPDFIEAGQKLVINTAEGTYVSRA"
     gene            21281..21670
                     /locus_tag="VQ543_000134"
     CDS             21281..21670
                     /locus_tag="VQ543_000134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HET2610940.1"
                     /translation="MGIEEQLGEIVIAPRVLEKIIAIATAKVEGVHSFSNRSVSDTLS
                     KLSLGRGVYLKNVDEELTADIYLYLEYGVKVPKVAVAIQKAVKDAVRNMADVELAAIN
                     IHVAGIVPDKTPKPELKDLFDEDFLND"
     gene            21663..22085
                     /gene="nusB"
                     /locus_tag="VQ543_000135"
     CDS             21663..22085
                     /gene="nusB"
                     /locus_tag="VQ543_000135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000203663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antitermination factor NusB"
                     /protein_id="HET2610941.1"
                     /translation="MTSPLLESRRQLRKCAFQALMSLEFGTNVETACRFAYTHDREDT
                     DVQLPAFLIDLVSGVQAKKEELDKQITQHLKVGWTIERLTLVERNLLRLGVFEITSFD
                     TPQLVAVNEAIELAKDFSDQKSARFINGLLSQFVTEEQ"
     gene            complement(22134..22511)
                     /locus_tag="VQ543_000136"
     CDS             complement(22134..22511)
                     /locus_tag="VQ543_000136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000244505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET2610942.1"
                     /translation="MVLSNGQPTFLSTILSFVLLVIIGPVFEETLDRGYFMNTFFPKS
                     KYYLDVILSGLIFGISHLILSHRDPISLLYYSLIGFFFALVYRSTDNLRLTILCHSFF
                     NFLNHAKPIWIFVYNYIYYHFFR"
     gene            complement(22852..23037)
                     /gene="briC"
                     /locus_tag="VQ543_000137"
     CDS             complement(22852..23037)
                     /gene="briC"
                     /locus_tag="VQ543_000137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000148168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biofilm-regulating peptide BriC"
                     /protein_id="HET2610943.1"
                     /translation="MTGTETFTVLSTEDLEQTSGGLAVWEDGYSRWLYYREFAPYMRQ
                     GALNSYIDAWKYGFRTG"
     gene            complement(23196..23963)
                     /locus_tag="VQ543_000138"
     CDS             complement(23196..23963)
                     /locus_tag="VQ543_000138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001017399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyl transferase
                     subunit alpha"
                     /protein_id="HET2610944.1"
                     /translation="MNIAKIVREAREQSRLTTLDFATGIFDEFIQLHGDRSFRDDGAV
                     VGGIGWLGDQAVTVVGIQKGKSLQDNLKRNFGQPHPEGYRKALRLMKQAEKFGRPVVT
                     FINTAGAYPGVGAEERGQGEAIARNLMEMSDLKVPIIAIIIGEGGSGGALALAVADRV
                     WMLENSIYAILSPEGFASILWKDGTRAMEAAELMKITSHELLEMDVVDKVISEVGLSS
                     KELIKSVKKELQTELARLSQKPLEELLEERYQRFRKY"
     gene            complement(23960..24826)
                     /locus_tag="VQ543_000139"
     CDS             complement(23960..24826)
                     /locus_tag="VQ543_000139"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001173351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyltransferase
                     subunit beta"
                     /protein_id="HET2610945.1"
                     /translation="MALFSKKDKYIRINPNRSVREKPQAKPEVPDELFSQCPGCKHTI
                     YQKDLGSERICPHCSYTFRISAQERLALTIDMGTFKELFTGIESKDPLHFPGYQKKLA
                     SMREKTGLHEAVVTGTALIKGQTVALGIMDSNFIMASMGTVVGEKITRLFEYATVEKL
                     PVVLFTASGGARMQEGIMSLMQMAKISAAVKRHSNAGLFYLTILTDPTTGGVTASFAM
                     EGDIILAEPQSLVGFAGRRVIENTVRESLPEDFQKAEFLLEHGFVDAIVKRRDLPDTI
                     ASLVRLHGGSPR"
     gene            complement(24863..26230)
                     /gene="accC"
                     /locus_tag="VQ543_000140"
     CDS             complement(24863..26230)
                     /gene="accC"
                     /locus_tag="VQ543_000140"
                     /EC_number="6.3.4.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000488661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="HET2610946.1"
                     /translation="MFRKILIANRGEIAVRIIRAARELGIATVAVYSTADKEALHTLL
                     ADEAVCIGPGKATESYLNINAVLSAAVLTEAEAIHPGFGFLSENSKFATMCEEVGIKF
                     IGPSGHVMDMMGDKINARAQMIKAGVPVIPGSDGEVHNSEEALIVAEKIGYPVMLKAS
                     AGGGGKGIRKVEKPDDLVSAFETASSEAKANYGNGAMYIERVIYPARHIEVQILGDEH
                     GHVIHLGERDCSLQRNNQKVLEESPSIAIGKTLRHEIGAAAVRAAEFVGYENAGTIEF
                     LLDEASSNFYFMEMNTRVQVEHPVTEFVSGVDIVKEQICIAAGQPLSVKQEDIVLRGH
                     AIECRINAENPAFNFAPSPGKITNLYLPSGGVGLRVDSAVYPGYTIPPYYDSMIAKII
                     VHGENRFDALMKMQRALYELEIEGVQTNADFQLDLISDRNVIAGDYDTSFLMETFLPK
                     YQEKE"
     gene            complement(26242..26664)
                     /gene="fabZ"
                     /locus_tag="VQ543_000141"
     CDS             complement(26242..26664)
                     /gene="fabZ"
                     /locus_tag="VQ543_000141"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HET2610947.1"
                     /translation="MIDIQGIKEALPHRYPMLLVDRVLEVSEDTIVAIKNVTINEPFF
                     NGHFPQYPVMPGVLIMEALAQTAGVLELSKPENKGKLVFYAGMDKVKFKKQVVPGDQL
                     VMTATFVKRRGTIAVVEAKAEVDGKLAASGTLTFAIGN"
     gene            complement(26661..27146)
                     /locus_tag="VQ543_000142"
     CDS             complement(26661..27146)
                     /locus_tag="VQ543_000142"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001052236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein"
                     /protein_id="HET2610948.1"
                     /translation="MNLNDIKDLMTQFDQSSLREFSYKNGTDELQFSKNEARPVPEVA
                     TQVAPAPVLATPSPVAPTSAPAETVAEEVPAPAEASVASEGNLVESPLVGVVYLAAGP
                     DKPAFVTVGDSVKKGQTLVIIEAMKVMNEIPAPKDGVVTEILVSNEEMVEFGKGLVRI
                     K"
     gene            complement(27149..28384)
                     /gene="fabF"
                     /locus_tag="VQ543_000143"
     CDS             complement(27149..28384)
                     /gene="fabF"
                     /locus_tag="VQ543_000143"
                     /EC_number="2.3.1.179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000774039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase II"
                     /protein_id="HET2610949.1"
                     /translation="MKLNRVVVTGYGVTSPIGNTPEEFWNSLATGKIGIGGITKFDHS
                     DFDVHNAAEIQDFPFDKYFVKKDTNRFDNYSLYALYAAQEAVNHANLDVEALNRDRFG
                     VIVASGIGGIKEIEDQVLRLHEKGPKRVKPMTLPKALPNMASGNVAMRFGANGVCKSI
                     NTACSSSNDAIGDAFRSIKFGFQDVMLVGGTEASITPFAIAGFQALTALSTTEDPTRA
                     SIPFDKDRNGFVMGEGSGMLVLESLEHAEKRGATILAEVVGYGNTCDAYHMTSPHPEG
                     QGAIKAIKLALEEAEISPEQVAYVNAHGTSTPANEKGESGAIVAVLGKEVPVSSTKSF
                     TGHLLGAAGAVEAIVTIEAMRHNFVPMTAGTSEVSDYIEANVVYGQGLEKEIPYAISN
                     TFGFGGHNAVLAFKRWENR"
     gene            complement(28406..29137)
                     /gene="fabG"
                     /locus_tag="VQ543_000144"
     CDS             complement(28406..29137)
                     /gene="fabG"
                     /locus_tag="VQ543_000144"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-[acyl-carrier-protein] reductase"
                     /protein_id="HET2610950.1"
                     /translation="MKLEHKNIFITGSSRGIGLAIAHKFAQAGANIVLNSRGAISEEL
                     LAEFSNYGIKVVPISGDVSDFADAKRMIDQAIAELGSVDVLVNNAGITQDTLMLKMTE
                     ADFEKVLKVNLTGAFNMTQSVLKPMMKAREGAIINMSSVVGLMGNIGQANYAASKAGL
                     IGFTKSVAREVASRNIRVNVIAPGMIESDMTAILSDKIKEATLAQIPMKEFGQAEQVA
                     DLTVFLAGQDYLTGQVIAIDGGLSM"
     gene            complement(29171..30091)
                     /gene="fabD"
                     /locus_tag="VQ543_000145"
     CDS             complement(29171..30091)
                     /gene="fabD"
                     /locus_tag="VQ543_000145"
                     /EC_number="2.3.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HET2610951.1"
                     /translation="MTKTAFLFAGQGAQYLGMGRDFYDQYPIVKETIDRASQVLGYDL
                     RYLIDTEEDKLNQTRYTQPAILATSVAIYRLLQEKGYQPDMVAGLSLGEYSALVASGA
                     LDFEDAVALVAKRGAYMEEAAPADSGKMVAVLNTPVEVIEEACQKASELGVVTPANYN
                     TPAQIVIAGEVVAVDRAVELLQEAGAKRLIPLKVSGPFHTALLEPASQKLAETLAQVS
                     FSDFTCPLVGNTEAAVMQKEDIAQLLTRQVKEPVRFYESIGVMQEAGISNFIEIGPGK
                     VLSGFVKKIDQTAHLAHVEDQASLVALLEK"
     gene            complement(30084..31058)
                     /gene="fabK"
                     /locus_tag="VQ543_000146"
     CDS             complement(30084..31058)
                     /gene="fabK"
                     /locus_tag="VQ543_000146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002896881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-[acyl-carrier-protein] reductase FabK"
                     /protein_id="HET2610952.1"
                     /translation="MKTRITELLKIDYPIFQGGMAWVADGDLAGAVSKAGGLGIIGGG
                     NAPKEVVKANIDKIKSLTDKPFGVNIMLLSPFVEDIVDLVIEEGVKVVTTGAGNPSKY
                     MERFHEAGIIVIPVVPSVALAKRMEKIGADAVIAEGMEAGGHIGKLTTMTLVRQVATA
                     ISIPVIAAGGIADGEGAAAGFMLGAEAVQVGTRFVVAKESNAHPNYKEKILKARDIDT
                     TISAQHFGHAVRAIKNQLTRDFELAEKDAFKQEDPDLEIFEQMGAGALAKAVVHGDVE
                     GGSVMAGQIAGLVSKEETAEEILKDLYYGAAKKIQEEASRWAGVVRND"
     gene            complement(31177..31401)
                     /locus_tag="VQ543_000147"
     CDS             complement(31177..31401)
                     /locus_tag="VQ543_000147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000257841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HET2610953.1"
                     /translation="MAVFEKVQEIIVEELGKDASEVTLESTFDDLDADSLDLFQVISE
                     IEDAFDIQIEAENDLKTVGDLVAYVEEQAK"
     gene            complement(31461..32435)
                     /locus_tag="VQ543_000148"
     CDS             complement(31461..32435)
                     /locus_tag="VQ543_000148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketoacyl-ACP synthase III"
                     /protein_id="HET2610954.1"
                     /translation="MAFAKISQVAHYVPEQVVTNHDLAQIMDTNDEWISSRTGIRQRH
                     ISRTESTSDLATEVAKKLMAKAGITGEELDFIILATITPDSMMPSTAARVQANIGANK
                     AFAFDLTAACSGFVFALSTAEKFIASGRFQKGLVIGSETLSKAVDWSDRSTAVLFGDG
                     AGGVLLEASEQEHFLAESLNSDGSRSECLTYGHSGLHSPFSDQESADSFLKMDGRTVF
                     DFAIRDVAKSIKQTIDESPIEVTDLDYLLLHQANNRILDKMARKIGVDRAKLPANMME
                     YGNTSAASIPILLSECVEQGLIPLDGSQTVLLSGFGGGLTWGTLILTI"
     gene            complement(32435..32869)
                     /locus_tag="VQ543_000149"
     CDS             complement(32435..32869)
                     /locus_tag="VQ543_000149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HET2610955.1"
                     /translation="MDYQRINEYLTSIFNNVLVIEEVNLRGSRFKDISIKEMHTIDVI
                     GKAPDVTPSQVSKELMVTLGTVTTSLNNLERKGYIERVRSEQDRRVVHLHLTKKGRLI
                     HRLHKRFHKAMVEKIIDGMSEEEIAVMGKGLTNLYQFLEDLK"
     gene            complement(32963..33748)
                     /locus_tag="VQ543_000150"
     CDS             complement(32963..33748)
                     /locus_tag="VQ543_000150"
                     /EC_number="4.2.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-CoA hydratase"
                     /protein_id="HET2610956.1"
                     /translation="MEHIIYQLEEDLAILTLNRPEVANGFHIPMCEEILEALTLAEEN
                     PAVHFILINANGKVFSVGGDLVEMKRAVDEDDIPSLTKIAELVNTISYKIKQIAKPVL
                     MEVDGAVAGAAANMAVAADFCLATDKAKFIQAFVGVGLAPDAGGIHLLSRSIGVTRAA
                     QLAMTGEALTAEKALEWGLVYRVSEAEKLEKTREQLLKKLRRASSNSYAAIKKLVWES
                     QFKDWQGYATLELNLQKSLAQTEDFKEGVRAHSERRRPKFTGK"
     gene            34073..35437
                     /locus_tag="VQ543_000151"
     CDS             34073..35437
                     /locus_tag="VQ543_000151"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004251870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate kinase"
                     /protein_id="HET2610957.1"
                     /translation="MKVVKFGGSSLASASQLEKVLNIVKSDSERRFVVVSAPGKRNAE
                     DTKVTDALIKYYRDYVAGNDISKSQSWIIDRYAAMVSELGLKPAVLEKISKSIHALAT
                     LPIEENEFLYDTFLAAGENNNAKLIAAYFNQNGIDARYMHPREAGIVVTSEPGHARII
                     PSSYDKIEELTNTNEVLVIPGFFGVTKENQICTFSRGGSDITGSIIAAGVKADLYENF
                     TDVDGIFAAHPGIIHQPHSIPELTYREMRELAYAGFSVLHDEALLPAYRGKIPLVIKN
                     TNNPDHPGTRIVLKHSNDEFPVVGIAGDSGFVSINMSKYLMNREVGFGRKVLQILEEL
                     NIGWEHMPTGIDDLSIILRSRQLTPIKEEEILRQLVQKAKVDHAEIEHDLSIIMIVGE
                     KMKSHIGVTATATRALSENKINIQMMSQGSSEVSIMFVVNKDQEKAAIKALYNAFFGE
                     SKED"
     gene            35440..35811
                     /locus_tag="VQ543_000152"
     CDS             35440..35811
                     /locus_tag="VQ543_000152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000079352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF956 family protein"
                     /protein_id="HET2610958.1"
                     /translation="MAQSLNKTVLLSTTGTSYLSIAGKVGKFLVGDQALEFYPDVNVE
                     QFIQIPWSHINQIGANVTGRKISRHFEVFTDKGKFLFASKDSGAILKIAREKLGNDKV
                     VKLPTLIQTISQKFKNLFAKK"
     gene            36025..37299
                     /gene="serS"
                     /locus_tag="VQ543_000153"
     CDS             36025..37299
                     /gene="serS"
                     /locus_tag="VQ543_000153"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000884256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HET2610959.1"
                     /translation="MLDIKRIRTDFEAVAEKLATRGVDAAVLNEMKEIDAKRRNILVK
                     VETLKAERNTVSAEIAQAKRNKENTDDKIAAMQNLSAEVKALDAELAEIDAKLTEFTT
                     TLPNIPADSVPVGTDEDDNVEVRRWGTPREFDFEPKAHWDLGEDLGILDWERGGKVTG
                     ARFLFYKGLGARLERAIYNFMLDEHGKEGYTEVITPYIVNHDSMFGTGQYPKFKEDTF
                     ELSDTNFVLIPTAEVPLTNYYRDEILDGKDLPIYFTAMSPSFRSEAGSAGRDTRGLIR
                     LHQFHKVEMVKFAKPEESYEELEKMTANAENILQKLNLPYRVVALSTGDMGFSAAKTY
                     DLEVWIPAQNNYREISSCSNTEDFQARRAQIRYRDEADGKVKLLHTLNGSGLAVGRTV
                     AAILENYQNEDGSVTIPEALRPYMGGAEVIKP"
     gene            complement(37324..38223)
                     /locus_tag="VQ543_000154"
     CDS             complement(37324..38223)
                     /locus_tag="VQ543_000154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000735961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TDT family transporter"
                     /protein_id="HET2610960.1"
                     /translation="MKKLPLVFSGCLLGLAGAGNLILDTLPVLSHLFSLTGLVLWIYF
                     LILHLFNWKETKQELTKPPLLSGMATFPMAGMILSTYVFRVFSYLPLVAQGIWWFSFL
                     LDLTLIAGFTIKFACSGRRVHATPSWTVLYVGIAVAALTYPLVGIIEIAYATLSFGFL
                     LTFYLYPLIYSDLKKHPLPLALLGQEGIYCAPFSLLLASLVRVGGTSLPTWVLIVMIL
                     ASQSFFFFVLTRLPNILKQGFQPAFSALTFPTIITATSLKMAQGILKLPFLDYLVLAE
                     TIICLTILFFVLGAYLIWLRKKV"
     gene            complement(38333..38881)
                     /locus_tag="VQ543_000155"
     CDS             complement(38333..38881)
                     /locus_tag="VQ543_000155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000206764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="HET2610961.1"
                     /translation="MTTFTIHTVESAPAEVKEILETVEKDNNGYIPNLIGLLANAPTV
                     LEAYQIVSSIHRRNSLTPVEREVVQITAAVTNGCAFCVAGHTAFSIKQIQMNDDLIQA
                     LRNRTPIETDPKLDTLAKFTLAVINTKGRVGDEALSEFLEAGYTQQNALDVVFGVSLA
                     ILCNYANNLANTPINPELQPYA"
     gene            complement(39099..40421)
                     /locus_tag="VQ543_000156"
     CDS             complement(39099..40421)
                     /locus_tag="VQ543_000156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:alanine symporter family protein"
                     /protein_id="HET2610962.1"
                     /translation="MLELLKSIDAFAWGPPLLILLVGTGIYLTMRLGLLQVLRLPKAF
                     QLIFIQDKGHGDVSSFAALCTALASTVGTGNIIGVATAIKVGGPGALFWMWMAAFFGM
                     ATKYAEGLLAIKYRTKDDHGAVAGGPMHYILLGMGEKWRPLAVLFAVAGVLVALLGIG
                     TFTQVNSITESIQNTTTISPAITALVLSVFVAIAVFGGLKSISKVSTTVVPFMALIYI
                     LGTLTVIFFNIGKIPGTIALVFTSAFSPLAAVGGFAGASVRMAIQNGVARGVFSNESG
                     LGSAPIAAAAAKTNEPVEQGLISMTGTFIDTLIICTLTGLTILVTGVWSGDLNGVALT
                     QSAFSTVFSHFGPALLTIFLVLFAFTTILGWNYYGERCFEFLFGARFIWLYRVFFVLM
                     VLLGGFIELDMVWIIADIVNALMALPNLIALLVLSPVVIAETKKYFDK"
     regulatory      complement(40512..40600)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00504"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="glycine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="glycine"
                     /db_xref="RFAM:RF00504"
     gene            complement(40764..43100)
                     /locus_tag="VQ543_000157"
     CDS             complement(40764..43100)
                     /locus_tag="VQ543_000157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HET2610963.1"
                     /translation="MNKKILETLEFDKVKALFDPHLLTEQGLEQLRQLAPTAKADKIK
                     QAFAEMKEMQALFVEQPHFTILSTKEIAGVCKRLEMGADLNIEEFLLLKRVLLASREL
                     QSFYANLENVSLEELALWFEKLHDFPQLQGNLQAFNDAGFIENFASEELARIRRKIHD
                     SESQVRDVLQDLLKQKAQMLTEGIVASRNGRQVLPVKNTYRNKIAGVVHDISASGNTV
                     YIEPREVVKLSEEIASLRADERYEMLRILQEISERVRPHAAEIANDAWIIGHLDLIRA
                     KVRFIQERQAVVPQLSENQEIQLLHVCHPLVKNAVANDVHFGQDLTAIVITGPNTGGK
                     TIMLKTLGLTQVMAQSGLPILADKGSRVGIFEEIFADIGDEQSIEQSLSTFSSHMTNI
                     VDILGKVNQHSLLLLDELGAGTDPQEGAALAMAILEDLRLRQIKTMATTHYPELKAYG
                     IETAFVQNASMEFDTATLRPTYRFMQGVPGRSNAFEIAKRLGLSEVIVGDASQQIDQD
                     NDVNRIIEQLEEQTLESRKRLDNIREVEQENLKMNRALKKLYNELNREKETELNKARE
                     QAAEIVDMALSESDQILKNLHSKSQLKPHEIIEAKAKLKKLAPEKVDLSKNKVLQKAK
                     KKRAPKVGDDIVVLSYGQRGTLTSQLKDGRWEAQVGLIKMTLEEKEFDLVQAQQEKPV
                     KKKQVNVVKRTSGRGPQARLDLRGKRYEEAMNELDTFIDQALLNNMAQVDIIHGIGTG
                     VIREGVTKYLQRNKHVKSFGYAPQNAGGSGATIVTFKG"
     gene            complement(43204..43752)
                     /locus_tag="VQ543_000158"
     CDS             complement(43204..43752)
                     /locus_tag="VQ543_000158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000622948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CvpA family protein"
                     /protein_id="HET2610964.1"
                     /translation="MISFLLLLVLVWGFYIGYRRGLLLQVYYLISAMASAFMAGQFYK
                     GLGEQFHLLLPYANSQEGQGTFFFPSDQLFQLDKVFYAGIGYLLVFGIFYSIGRLLGL
                     LLHLIPSKKLGGKLFQVSAGILSMLVTLFVLQMALTILATIPMAVIQNPLEKSIVAKH
                     IIQSIPITTSWLKQIWVTNLIG"
     gene            complement(43749..44051)
                     /gene="zapA"
                     /locus_tag="VQ543_000159"
     CDS             complement(43749..44051)
                     /gene="zapA"
                     /locus_tag="VQ543_000159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZapA"
                     /protein_id="HET2610965.1"
                     /translation="MANLNRFKFTFGKKSLTLTSEHDNLFMEEIAKVATEKYQAIKEQ
                     MPSADDETIALLLAVNCLSTQLSREIEFDDKEQELEELRHKLVTCKQEQSKIEDSL"
     gene            44138..45019
                     /locus_tag="VQ543_000160"
     CDS             44138..45019
                     /locus_tag="VQ543_000160"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000146880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HIII"
                     /protein_id="HET2610966.1"
                     /translation="MASITLTPSEKDIQAFLEHYQTSLAPSKNPYIRYFLKLPQATVS
                     IYTSGKILLQGEGAEKYASFFGYQLVEENRGQNLPLIGTDEVGNGSYFGGLAVVAAFV
                     TSDQHDFLRKLGVGDSKTLTDQKIRQIAPILKEKIQHQALLLSPSKYNEVIGDRYNAV
                     SVKVALHNQAIYLLLQKGVQPEKIVIDAFTSAKNYDKYLAQEANRFSNPISLEEKAEG
                     KYLSVAVSSVIARDLFLENLENLGRELGYQLPSGAGTASDKVASQILQAYGMQGLSFC
                     AKLHFKNTEKAKKRLER"
     gene            45023..45637
                     /gene="lepB"
                     /locus_tag="VQ543_000161"
     CDS             45023..45637
                     /gene="lepB"
                     /locus_tag="VQ543_000161"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001048155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HET2610967.1"
                     /translation="MNSFKNFLKEWGLFLLILSLLALSRIFFWSNVRVEGHSMDPTLA
                     DGEILFVVKHLPIDRFDIVVAHEEDGNKDIVKRVIGMPGDTIRYENDKLYINDKETDE
                     PYLADYIKRFKDDKLQSTYSGKGFEGNKGTFFRSIAQKAQAFTVDVNYNTNFSFTVPE
                     GEYLLLGDDRLVSSDSRHVGTFKAKDITGEAKFRFWPITRIGTF"
     gene            45916..48282
                     /locus_tag="VQ543_000162"
     CDS             45916..48282
                     /locus_tag="VQ543_000162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000454449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RecD-like DNA helicase"
                     /protein_id="HET2610968.1"
                     /translation="MEVYFSGTIERIIFENPSNFYRILLLEIDDTDAEDFDDFEIIVT
                     GTMADVIEGEDYTFWGQIVQHSKYGEQLQISRYDRAKPTSKGLVKYFSSSHFKGIGLK
                     TAQKIVDTYGENTIDEILQHPEKLEGIAGLSAKNREAFVSTLRLNYGTEMVLSKLANY
                     GIPNKLAFQIQDFYKEETLDVVENYPYQLVEDIKGLGFTIADQLAEELGIESQAPERF
                     RAGLVHSLFQACMETGDTYVEARDLLEQTLTLLESSRPVELDPSQVAQELSYLIEEDK
                     VQQIDTKIFDNSLFFAEEGIRSHLVRILEKGKQKSHDLETIQKHITTIEEELGIEYDN
                     IQKQAICDAIQNKVFILTGGPGTGKTTVINGIIAVYALLEGLDFRKKSNLPILLAAPT
                     GRAARRMNELTGLPSATIHRHLGMTGDDDTSHLEDYLDADFIIVDEFSMVDTWLANQL
                     FSNISSNSKILIVGDSDQLPSVSPGQVLADLLHIPLIPQTHLEKIYRQSKESTIVTLA
                     SQIRQGILPADFTQKKADRSYFEIASGHIPATIEKILGAALRNGIPARDIQVLAPMYR
                     GTAGIDAINQLMQDLLNPPQKDQLSFEAPQCHYRKGDKVIHLVNDAEINVFNGDLGAI
                     TDLIPGKYTESKQDEIVIDFDGNEVSYPRNEWYKIRLAYAMSIHKSQGSEFPVVILPI
                     TSASRRMLERNLIYTAITRAKSKLILLGELQAFDYATQHIGTARKTYLIERFSDLLEN
                     VEEKQQAVSETVTSSASEQSYILTEENWDSIPAMIGITDTDLKEIFGK"
     gene            complement(48330..49613)
                     /locus_tag="VQ543_000163"
     CDS             complement(48330..49613)
                     /locus_tag="VQ543_000163"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trigger factor"
                     /protein_id="HET2610969.1"
                     /translation="MSVSFENKETNRGVLTFTISQDQIKPELDRVFKSVKKSLNVPGF
                     RKGHLPRPIFDKKFGEESLYQDVMNALLPNAYEAAVKEAGLEVVAQPKIDVTSMEKGQ
                     DWVIAAEVVTKPEVKLGDYKNLEVSVDVEKEVTDADVEERIERERNNLAELVIKEAAA
                     EDGDTVVIDFVGSIDGVEFDGGKGENFSLGLGSGQFIPGFEDQLVGHSAGETVDVIVT
                     FPEDYQAEDLAGKEAKFVTTIHEVKAKEVPALDDELAKDIDEEVETLADLKEKYRKEL
                     AAAKEEAYKDAVEGAAIDTAVENAEIVELPEEMIHEEVHRSVNEFLGNLQRQGINPDM
                     YFQITGTTQEDLHNQYQAEAESRTKTNLVIEAVAKAEGFDASEEEIQKEVEQLAADYN
                     MEVAQVQNLLSADMLKHDITIKKAVELITSTATVK"
     gene            complement(49807..50166)
                     /locus_tag="VQ543_000164"
     CDS             complement(49807..50166)
                     /locus_tag="VQ543_000164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HET2610970.1"
                     /translation="MDSPKSLASYRVIGISDRVLEILKEYLLLEEGDYIFTNNGSPLM
                     ITCFNYFLKNRFRKSEIKKDDFVLTAHVFRYSHISLLAELEVPITAIMDRVDYTNETK
                     ILSVYTHVTEKMKSNIT"
     gene            complement(50465..51094)
                     /locus_tag="VQ543_000165"
     CDS             complement(50465..51094)
                     /locus_tag="VQ543_000165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine protease"
                     /protein_id="HET2610971.1"
                     /translation="MVLSKYYGVADGMNVEGRGSANFIKDNVLITAAHNYYRHDYGKE
                     ADDIYVLPTVSPSQEPFGKIKVKEVRYLKEFRNLNSKDAREYDLALLILEEPIGAKLG
                     TLGLPTSQKNLTGITVTITGYPSYNFKVHQMYTDKKQVLSDDGMFLDYQVDTLEGSSG
                     STVYDASHRVVGVHTLGDGANQINSAVKLNERNLPFIYSVLKGYSLEGW"
     gene            complement(51139..51378)
                     /locus_tag="VQ543_000166"
     CDS             complement(51139..51378)
                     /locus_tag="VQ543_000166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000754500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2610972.1"
                     /translation="MKKTVYKKLGISIIASTLLASQLSTVSALSVISSTGEEYEVSET
                     LEKGPGSNDSSLSEISPTYGSYYQKQSEVLSVMMI"
     gene            complement(51528..51794)
                     /locus_tag="VQ543_000167"
                     /pseudo
     CDS             complement(51528..51794)
                     /locus_tag="VQ543_000167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000060522.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
     gene            complement(51819..52127)
                     /locus_tag="VQ543_000168"
     CDS             complement(51819..52127)
                     /locus_tag="VQ543_000168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HET2610973.1"
                     /translation="MDWDFADTCWEKEPRKYQYVAANYLKAMQSYLKETDLPKLEQLV
                     VTKSWWDTVDILDRVVGSLVYEHPELEEIILILFENLFKPRQLYLQPQNSVLRLQIAS
                     "
     gene            complement(52052..52294)
                     /locus_tag="VQ543_000169"
     CDS             complement(52052..52294)
                     /locus_tag="VQ543_000169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HET2610974.1"
                     /translation="MSLADLLEELEAAKDSKKARPMEAYMRHQFSFLGIAVPERNKLY
                     KNIYQKRKKQRLSIGILQTLAGKRSLENTNMWLLTI"
     gene            complement(52295..52927)
                     /locus_tag="VQ543_000170"
     CDS             complement(52295..52927)
                     /locus_tag="VQ543_000170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET2610975.1"
                     /translation="MKILLVDDHEMVRLGLKSYFDLQDDVEVVGEASNGSQGIDLALE
                     LRPDVIVMDIVMPEMNGIDATLAILKEWPEAKILIVTSYLDNEKIMPVLDAGAKGYML
                     KTSSADELLHAVSKVAAGELAIEQEVSKKVEYHRNHMELHEELTARERDVLQLIAKGY
                     ENQRIADDLFISLKTVKTHVSNILAKLEVSDRTQAAVYAFQHHLVGQEEF"
     gene            complement(52941..53936)
                     /locus_tag="VQ543_000171"
     CDS             complement(52941..53936)
                     /locus_tag="VQ543_000171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HET2610976.1"
                     /translation="MKKQAYVIIALTSFLFVFFFSHSLLEILDFDWSIFLYDVEKTEK
                     FVFLLLVFSMSMTCLLALFWRGIEELSLRKMQANLKRLLAGQEVVQVVDPDLDASFKS
                     LSGKLNLLTEALQKAENHSLDQEEEIIEKERKRIARDLHDTVSQELFAAHIILSGISQ
                     QALKLDREKMQTQLQSVTAILETAQKDLRVLLLHLRPVELEQKSLIEGIQILLKELED
                     KSDLRVSLKQNMTKLPKKIEEHIFRILQELISNTLRHAQASCLDVYLYQTDVELQLKV
                     VDNGIGFRLGSLDDLSYGLRNIKERVEDMAGTVQLLTAPKQGLAVDIRIPLLDKE"
     gene            complement(53933..54631)
                     /locus_tag="VQ543_000172"
     CDS             complement(53933..54631)
                     /locus_tag="VQ543_000172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-active antibiotics response protein"
                     /protein_id="HET2610977.1"
                     /translation="MRKFKIFLFIEACLLTGALILMVSEHFSRFLLILFLFLLLIRYY
                     TGKEGNNLLLVAATILFFFIVMLNPFVILAIFVAVIYSLFLLYPMMNQEKEQTNLVFE
                     EVVTVKKEKNRWFGNLHHFSSYQTCQFDDINLFRFMGKDTIHLERVILTNHDNVIILR
                     KMVGTTKIIVPVDVEVSLSVNCLYGDLTFFNQPKRALRNEHYHQETKDYLKSNKSVKI
                     FLTTMIGDVEVVRG"
     gene            complement(54709..55719)
                     /locus_tag="VQ543_000173"
     CDS             complement(54709..55719)
                     /locus_tag="VQ543_000173"
                     /EC_number="5.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000210649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 2 isopentenyl-diphosphate Delta-isomerase"
                     /protein_id="HET2610978.1"
                     /translation="MTTNRKDEHILYALEQKSSYNSFDEVELIHSSLPLYNLDEIDLS
                     TEFAGRKWDFPFYINAMTGGSNKGREINQKLAQVAESCGILFVTGSYSAALKNPTDDS
                     FSVKSSHPNLLLGTNIGLDKPVELGLQTVEEMNPVLLQVHVNVMQELLMPEGERKFRS
                     WQSHLADYSKQIPVPIVLKEVGFGMDAKTIERAYEFGVRTVDLSGRGGTSFAYIENRR
                     SGQRDYLNQWGQSTMQALLNAQEWKDKVELLVSGGVRNPLDMIKCLVFGAKAVGLSRT
                     VLELVETYTVEEVIGIVQGWKADLRLIMCSLNCATIADLQKVDYLLYGKLKEAKDQMK
                     KA"
     gene            complement(55703..56710)
                     /locus_tag="VQ543_000174"
     CDS             complement(55703..56710)
                     /locus_tag="VQ543_000174"
                     /EC_number="2.7.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000562378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomevalonate kinase"
                     /protein_id="HET2610979.1"
                     /translation="MIAVKTCGKLYWAGEYAILEPGQLALIKDIPIYMRAEIAFSDSY
                     RIYSDMFDFAVDLTPNPDYSLIQETIALMGDFLAVRGQNLRSFSLEICGKMEREGKKF
                     GLGSSGSVVVLVVKALLALYDVSVDQELLFKLTSAVLLKRGDNGSMGDLACIVAEDLV
                     LYQSFDRQKVAAWLEEENLATVLERDWGFSISQVKPTLECDFLVGWTKEVAVSSHMVQ
                     QIKQNINQNFLSSSKETVVSLVEALEQGKSEKIIEQVEVASKLLEGLSTDIYTPLLRQ
                     LKEASQDLQAVAKSSGAGGGDCGIALSFDAQSTKTLKNRWADLGIELLYQERIGHDDK
                     S"
     gene            complement(56697..57650)
                     /gene="mvaD"
                     /locus_tag="VQ543_000175"
     CDS             complement(56697..57650)
                     /gene="mvaD"
                     /locus_tag="VQ543_000175"
                     /EC_number="4.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000373478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diphosphomevalonate decarboxylase"
                     /protein_id="HET2610980.1"
                     /translation="MDREPVTVRSYANIAIIKYWGKKKEKEMVPATSSISLTLENMYT
                     ETTLSPLPANVIADEFYINGQLQNEVEHAKMSKIIDRYRPAGEGFVRIDTQNNMPTAA
                     GLSSSSSGLSALVKACNAYFKLGLDRSQLAQEAKFASGSSSRSFYGPLGAWDKDSGEI
                     YSVETDLKLAMIMLVLEDKKKPISSRDGMKLCVETSTTFDDWVRQSEKDYQDMLIYLK
                     ENDFAKIGELTEKNALAMHATTKTASPAFSYLTDASYEAMDFVRQLREKGEACYFTMD
                     AGPNVKVFCQEKDLEHLSEIFGQRYRLIVSKTKDLSQDDCC"
     gene            complement(57632..58510)
                     /gene="mvk"
                     /locus_tag="VQ543_000176"
     CDS             complement(57632..58510)
                     /gene="mvk"
                     /locus_tag="VQ543_000176"
                     /EC_number="2.7.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mevalonate kinase"
                     /protein_id="HET2610981.1"
                     /translation="MTKKVGVGQAHSKIILIGEHAVVYGYPAISLPLLEVEVTCKVVP
                     AESPWRLYEEDTLSMAVYASLEYLDITEACIRCEIDSAIPEKRGMGSSAAISIAAIRA
                     VFDYYQADLPHDVLEILVNRAEMIAHMNPSGLDAKTCLSDQPIRFIKNVGFTELEMDL
                     SAYLVIADTGVYGHTREAIQVVQNKGKDALPFLHALGELTQQAEVAISQKDAEGLGQI
                     LSQAHLHLKEIGVSSPEADFLVETTLSHGALGAKMSGGGLGGCIIALVTNLTHAQELA
                     ERLEEKGAVQTWIESL"
     gene            complement(58632..58961)
                     /locus_tag="VQ543_000177"
     CDS             complement(58632..58961)
                     /locus_tag="VQ543_000177"
                     /inference="COORDINATES: protein motif:HMM:NF024736.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET2610982.1"
                     /translation="MTRKAYDTDLNDQEWAKIEPYFSKHRTYKWPKRVLVNETLYVTK
                     TGCQWRMIPHDFPLYLTVWSFFRRSMTTGWFQVNGRWYYAYSSGALAVNTTVDGYSVN
                     YNGEWVQ"
     gene            59623..59959
                     /locus_tag="VQ543_000178"
                     /pseudo
     CDS             59623..59959
                     /locus_tag="VQ543_000178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001811282.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic-modifying protein"
     gene            59859..60446
                     /locus_tag="VQ543_000179"
     CDS             59859..60446
                     /locus_tag="VQ543_000179"
                     /inference="COORDINATES: protein motif:HMM:NF017000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2610983.1"
                     /translation="MTILLKLSSTIVYGEIYHYFLQRDTAKESILDYSFAHGYCEIAY
                     ALFAYSKVLEPSMFYNDLHTFHAELKKLLEKVTSNTENLGNLQLSWCEGISGIILYLC
                     MYDCDGNKDIISKYQEFVFNHHLKMMTGYCHGITSLLQTTVYNQNKLLMKKIQQVILA
                     CSERDDHGLLMFQGDSGKADLFDFGIGSRGYIGVY"
     gene            60489..61721
                     /locus_tag="VQ543_000180"
     CDS             60489..61721
                     /locus_tag="VQ543_000180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000765682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HET2610984.1"
                     /translation="MKLFWTNNIYRQLLLNSCFSSFGDSIFYLAIINYVAQYNFAPLA
                     ILLISISEMVPLLSQLFLGILGDFQENRVKHALCIAKIKILLYAILTVFLVLSPFSLV
                     SVIMIVIINLISDTLSYLSAYMMNALYISVIKDDLHDAMGFRQSLMRVVHIVANLAGA
                     FLINVISIQTISLINTLTFVIAFLGLYVIRHTLYEVEKRIEMSHTALSFKKYFQHLKQ
                     SLAVLLRLKDTVILLFLTTSMIAILDVSPRLIALRFIQQTLAQLSIGQLFALLSIIMS
                     CGAILGNMTSSNLFKNIRFTHLLVFCEISLLALITSILCQAYIVIFVTSFISSTIIGI
                     LSPRLQAAVFAHIPSDKMGTVGSALSTVDILAPSLLSLLALSIASGVSVQLALIFLYL
                     ILIALIFCQWLVKFNTHN"
     gene            complement(61839..62795)
                     /gene="cbpC"
                     /locus_tag="VQ543_000181"
     CDS             complement(61839..62795)
                     /gene="cbpC"
                     /locus_tag="VQ543_000181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000771060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein CbpC"
                     /protein_id="HET2610985.1"
                     /translation="MKLLKKMMQVLLAVFFFGLLATNTVFANTTGGRFVDKDNRKYYV
                     KDDHKAIYWHKIDGKTYYFGDIGEMVVGWQYLEIPGTGYRDDLFDNRPVFEIGLQEKW
                     YYFGQDGALLEQTDKQVLEAKTSENTGKVYGEQYPLSAEKRTYYFDNNYAVKTGWIYE
                     DGNWYYLNKLGNFGDDSYNPLPIGEVAKGWTQDFHVTIDIDRSKPAPWYYLRSSGAMA
                     TGWYQEGTTWYYLDQPNGDMKTGWQNLGNKWYYLRSSGAMATGWYQDGSTWYYLNAGN
                     GDMKTGWFQVNGNWYYAYSSGALAVNTTVDGYSVNYNGEWVR"
     gene            complement(62893..63582)
                     /locus_tag="VQ543_000182"
     CDS             complement(62893..63582)
                     /locus_tag="VQ543_000182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000518023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET2610986.1"
                     /translation="MGKRILLLEKERNLAHFLSLELQKEQYRVDLVEEGQKALSMALQ
                     TDYDLILLNVNLGDMMAQDFAEKLSRTKPASVIMILDHWEDLQEELEVVQRFAVSYIY
                     KPVFIENLVARISAIFRGRDFIDQHCSLMKVPRTYRNLRIDVEHHTVYRGEEMIALTR
                     REYDLLATLMGSKKVLTREQLLESVWKYESATETNIVDVYIRYLRSKLDVKGQKSYIK
                     TVRGVGYTMQE"
     gene            complement(63594..65018)
                     /gene="gndA"
                     /locus_tag="VQ543_000183"
     CDS             complement(63594..65018)
                     /gene="gndA"
                     /locus_tag="VQ543_000183"
                     /EC_number="1.1.1.44"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004185725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent phosphogluconate dehydrogenase"
                     /protein_id="HET2610987.1"
                     /translation="MTKANFGVVGMAVMGRNLALNIESRGYTVAIYNRSKEKTEDVIA
                     CHPEKNFVPSYDVESFVNSIEKPRRIMLMVQAGPGTDATIQALLPHLDKGDILIDGGN
                     TFYKDTIRRNEELANSGINFIGTGVSGGEKGALEGPSIMPGGQKEAYELVSDVLEEIS
                     AKAPEDGKPCVTYIGPDGAGHYVKMVHNGIEYGDMQLIAESYDLMQHLLGLSAEDMAE
                     IFTEWNKGELDSYLIEITADILSRKDDEDQDGPIVDYILDAAGNKGTGKWTSQSSLDL
                     GVPLSLITESVFARYISTYKEERVHASKVLPKPAAFNFEGDKAELIEKIRQALYFSKI
                     ISYAQGFAQLRVASKENNWNLPFADIASIWRDGCIIRSRFLQKITDAYNRDADLANLL
                     LDEYFLDVTAKYQQAVRDIVALAVQAGVPVPTFSAAITYFDSYRSADLPANLIQAQRD
                     YFGAHTYQRKDKEGTFHYSWYDEK"
     gene            complement(65094..66488)
                     /gene="mapZ"
                     /locus_tag="VQ543_000184"
     CDS             complement(65094..66488)
                     /gene="mapZ"
                     /locus_tag="VQ543_000184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000039255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mid-cell-anchored protein MapZ"
                     /protein_id="HET2610988.1"
                     /translation="MSKKRRNRHKKEGQEPQFDFDEAKELTVGQAIRKNEEVEAGVLP
                     EDSILDKYVKQHRDEIEADKFATRQYKKEEFVETQSLDDLIQEMREAVEKSEASSEEV
                     PSSEDILLPLPLDDEEQGLDPLLLDDENPTEMTEEVEEEQNLSRLDQEDSEKKSKKGF
                     ILTVLALVSVIICVSAYYVYRQVARSTKEIETSQSTTANQSDVDDFNTLYDAFYTNSN
                     KTALKNSQFDKLSQLKTLLDKLEGSREHTLAKSKYDSLVTQIKAIQDVNAQFEKPAIV
                     DGVLDTNAKAKSDAKFTDIKTGNTELDKVLDKAISLGKSQQTSTSSSSSSQTSSSSSS
                     QASSNTTSEPKPSSSNETRSSRSEVNMGLSSAGVAVQRSASRVAYNQSAIDDSNNSAW
                     DFADGVLEQILATSRSRGYITGDQYILERVNIVNGNGYYNLYKPDGTYLFTLNCKTGY
                     FVGNGAGHADDLDY"
     gene            complement(66501..67658)
                     /locus_tag="VQ543_000185"
     CDS             complement(66501..67658)
                     /locus_tag="VQ543_000185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent RNA methyltransferase"
                     /protein_id="HET2610989.1"
                     /translation="MKKEFNLIATVAAGLEAVVGREVRELGYDCQVENGRVRFQGDVR
                     AIIETNLWLRAADRIKIIVGTFPAKTFEELFQGVFALDWENYLPLGARLPISKAKCVK
                     SKLHNEPSVQAISKKAVVKKLQKHYARPEGVPLMENGPEFKIEVSILKDVATVMIDTT
                     GSSLFKRGYRTEKGGAPIKENMAAAILQLSNWYPDKPLIDPTCGSGTFCIEAVMIARK
                     MAPGLRRSFAFEEWNWISDRLIQEVRTEAAKKVERKLELDIMGCDIDARMVEIAKANA
                     QAAGVAGDITFKQMRVQDLRSDKINGVIISNPPYGERLSDDAGVTKLYAEMGQVFAPL
                     KTWSKFILTSDEAFESKYGSQADKKRKLYNGTLKVDLYQYFGQRVKRQEVK"
     gene            complement(67743..68123)
                     /gene="rnpB"
                     /locus_tag="VQ543_000186"
     ncRNA           complement(67743..68123)
                     /ncRNA_class="RNase_P_RNA"
                     /gene="rnpB"
                     /locus_tag="VQ543_000186"
                     /product="RNase P RNA component class B"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00011"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00011"
     gene            complement(68144..68473)
                     /gene="gpsB"
                     /locus_tag="VQ543_000187"
     CDS             complement(68144..68473)
                     /gene="gpsB"
                     /locus_tag="VQ543_000187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000146522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division regulator GpsB"
                     /protein_id="HET2610990.1"
                     /translation="MASIIFSAKDIFEQEFGREVRGYNKVEVDEFLDDVIKDYETYAA
                     LVKSLRQEIADLKEELTRKPKPSPVQAEPLEAAITSSMTNFDILKRLNRLEKEVFGKQ
                     ILDNSDF"
     gene            complement(68543..69070)
                     /locus_tag="VQ543_000188"
     CDS             complement(68543..69070)
                     /locus_tag="VQ543_000188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1273 domain-containing protein"
                     /protein_id="HET2610991.1"
                     /translation="MATALVLGYSAFDLGLFSDKDPRLKLIKKAIRKDLEAMAADGVS
                     WLVFTGSLGFEYWVLEVAQEMKTEYGFQLATIFAFETHGENWNEGNQMKLSRFKQVDF
                     VKYAYPRYEHKGQLRDYQQFLLENTTSSYLFYDEENETKLAYFYQKMKNQEDYFIKRL
                     TFDQLNELAENFSEN"
     gene            69136..69732
                     /gene="recU"
                     /locus_tag="VQ543_000189"
     CDS             69136..69732
                     /gene="recU"
                     /locus_tag="VQ543_000189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RecU"
                     /protein_id="HET2610992.1"
                     /translation="MINYPHKVSSQKRQTSLSQPKNFANRGMSFEKMINATNDYYLSQ
                     GLAVIHKKPTPIQIVQVDYPQRSRAKIVEAYFRQASTTDYSGVYNGYYIDFEVKETKQ
                     KRAIPMKNFHPHQIQHMEQVLAQQGICFVLLHFSSQQETYLLPAFDLIRFYHQDKGQK
                     SMPLEYIREYGYEIKAGAFPQIPYLNVIKEHLLGGKTR"
     gene            69729..71888
                     /locus_tag="VQ543_000190"
     CDS             69729..71888
                     /locus_tag="VQ543_000190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001040003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 1A"
                     /protein_id="HET2610993.1"
                     /translation="MNKPTILRLIKYLSISFLSLVIAAIVLGGGVFFYYVSKAPSLSE
                     SKLVATTSSKIYDNKNQLIADLGSERRVNAQANDIPTDLVKAIVSIEDHRFFDHRGID
                     TIRILGAFLRNLQSNSLQGGSTLTQQLIKLTYFSTSTSDQTISRKAQEAWLAIQLEQK
                     ATKQEILTYYINKVYMSNGNYGMQTAAQNYYGKDLNNLSLPQLALLAGMPQAPNQYDP
                     YSHPEAAQDRRNLVLSEMKNQGYISAEQYEKAVNTPITDGLQSLKSASNYPAYMDNYL
                     KEVINQVEEETGYNLLTTGMDVYTNVDQEAQKHLWDIYNTDEYVAYPDDELQVASTIV
                     DVSNGKVIAQLGARHQSSNVSFGINQAVETNRDWGSTMKPITDYAPALEYGIYDSTAT
                     IVHDEPYNYPGTNTPVYNWDRGYFGNITLQYALQQSRNVPAVETLNKVGLNRAKTFLN
                     GLGIDYPSIHYSNAISSNTTESDKKYGASSEKMAAAYAAFANGGTYYKPMYIHKVVFS
                     DGSEKEFSNVGTRAMKETTAYMMTDMMKTVLTYGTGRNAYLAWLPQAGKTGTSNYTDE
                     EIENHIKTSQFVAPDELFAGYTRKYSMAVWTGYSNRLTPLVGNGLTVAAKVYRSMMTY
                     LSEGSNPEDWNIPEGLYRNGEFVFKNGARSTWSSPAPQQPPSTESSSSSSDSSTSQSS
                     STTPSTNNSTTTNPNNNTQQSNTTPDQQNQNPQPAQP"
     gene            complement(72055..77358)
                     /locus_tag="VQ543_000191"
     CDS             complement(72055..77358)
                     /locus_tag="VQ543_000191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001032503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK signal domain/LPXTG anchor domain surface
                     protein"
                     /protein_id="HET2610994.1"
                     /translation="MNKGLFEKRCKYSIRKFSLGVASVMIGAAFFGTSPVLADSVQSG
                     STANLPADLATALATANENDGRDFEAPKVGEDQGSPEVTDGPKTEEELLALEKEKPAE
                     EKPKEDKPAAAKPETPKTVTPEWQTVEKKEQQGTVTIREEKGVRYNQLFSTAQNDNAG
                     KPALFEKKGLTVDANGNATVDLTFKEDSEKGKSRFGVFLKFKDTNNNVFVGYDKDGWF
                     WEYKTPGNSTWYKGNRVVAPEPGSVNRLSITLKSDGQLNASNNDVNLFDTVTLPGAVN
                     DNLKNEKKILLKAGTYGNDRTVVSVKTDNQEGVKADDTPAQKETGPVVDDSKVTYDTI
                     QSKVLKAVIDQAFPRVKEYSLNGHTLPGQVQQFNQVFINNHRITPEVTYKKINETTAE
                     YLMKLRDDAHLINAEMTVRLQVVDNQLHFDVTKIVNHNQVTPGQKIDDERKLLSSISF
                     LGNALVSVSSDQTGAKFDGATMSNNTHVSGDDHIDVTNPMKDLAKGYMYGFVSTDKLA
                     AGVWSNSQNSYGGGSNDWTRLTAYKETVGNANYVGIHSSEWQWEKAYKGIVFPEYTKE
                     LPSAKVVITEDANADKKVDWQDGAIAYRSIMNNPQGWEKVKDITAYRIAMNFGSQAQN
                     PFLMTLDGIKKINLHTDGLGQGVFLKGYGSEGHDSGHLNYADIGKRIGGVEDFKTLIE
                     KAKKYGAHLGIHVNASETYPESKYFNEKILRKNPDGSYSYGWNWLDQGINIDAAYDLA
                     HGRLARWEDLKKKLGDGLDFIYVDVWGNGQSGDNGAWATHVLAKEINKQGWRFAIEWG
                     HGGEYDSTFHHWAADLTYGGYTNKGINSAITRFIRNHQKDAWVGDYRSYGGAANYPLL
                     GGYSMKDFEGWQGRSDYNGYVTNLFAHDVMTKYFQHFTVSKWENGTPVTMTDNGSTYK
                     WTPEMRVELVDADNNKVVVTRKSNDVNSPQYRERTVTLNGRVIQDGSAYLTPWNWDAN
                     GKKLSTDKEKMYYFNTQAGATTWTLPSDWAKSKVYLYKLTDQGKTEEQELTVKDGKIT
                     LDLLANQPYVLYRSKQTNPEMSWSEGMHIYDQGFNSGTLKHWTISGDASKAEIVKSQG
                     ANDMLRIQGNKEKVSLTQKLTGLKPNTKYAVYVGVDNRSNAKASITVNTGEKEVTTYT
                     NKSLALNYVKAYAHNTRRNNATVNDTSYFQNMYAFFTTGSDVSNVTLTLSREAGDQAT
                     YFDEIRTFENNSSMYGDKHDTGQGTFKQDFENVAQGIFPFVVGGVEGVEDNRTHLSEK
                     HDPYTQRGWNGKKVDDVIEGNWSLKTNGLVSRRNLVYQTIPQNFRFEAGKTYRVTFEY
                     EAGSDNTYAFVVGKGEFQSGRRGTQASNLEMHELPNTWTDSKKAKKATFLVTGAETGD
                     TWVGIYSTGNASNTRGDSGGNANFRGYNDFMMDNLQIEEITLTGKMLTENALKNYLPT
                     VAMTNYTKESMDALKEAVFNLSQADDDISVEEARAEIAKIEALKNALVQKKTALVADD
                     FASLTAPAQAQEGLANAFDGNLSSLWHTSWNGGDVGKPATMVLKEPTEITGLRYVPRG
                     SGSNGNLRDVKLVVTDESGKEHTFTATDWPDNNKPKDIDFGKTIKAKKIVLTGTKTYG
                     DGGDKYQSAAELIFTRPQVAETPLDLSGYEAALAKAQKLTDKDNQEEVASVQASMKYA
                     TDNHLLTERMVEYFADYLNQLKDSATKPDAPTVEKPEFKLSSLVSDQGKTPDYKQEIA
                     RPETPEQILPATGESQSDTALFLASVSLALSALFVVKTKKD"
     gene            complement(77659..79641)
                     /locus_tag="VQ543_000192"
     CDS             complement(77659..79641)
                     /locus_tag="VQ543_000192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HET2610995.1"
                     /translation="MKSSKLLALAGVTLLAATTLAACSGSGSSTKGEKTFSYIYETDP
                     DNLNYLTTAKAATANITSNVVDGLLENDRYGNFVPSMAEDWSVSKDGLTYTYTIRKDA
                     KWYTSEGEEYAAVKAQDFVTGLKYAADKKSDALYLVQESIKGLDAYVKGEIKDFSQVG
                     IKALDDQTVQYTLNKPESFWNSKTTMGVLAPVNEEFLNSKGDDFAKATDPSSLLYNGP
                     YLLKSIVTKSSVEFAKNPNYWDKDNVHVDKVKLSFWDGQDTSKPAENFKDGSLTAARL
                     YPTSASFAELEKSMKDNIVYTQQGSITYLVGTNIDRQSYKYTSKTSDEQKASTKKALL
                     NKDFRQAIAFGFDRTAYASQLNGQTGASKILRNIFVPPTFVQADGKNFGDMVKEKLVT
                     YGDEWKDVNLADSQDGLYNPEKAKAEFAKAKSALQAEGVTFPIHLDMPVDQTATTKVQ
                     RVQSMKQSLEATLGADNVIIDIQQLQKDEVNNITYFAENAAGEDWDLSDNVGWGPDFA
                     DPSTYLDIIKPSVGESTKTYLGFDSGEDNVAAKKVGLYDYEKLVTEAGDEATDVAKRY
                     DKYAAAQAWLTDSALIIPTTSRTGRPILSKMVPFTIPFALSGNKGTSEPVLYKYLELQ
                     DKAVTVDEYQKAQEKWMKEKEESNKKAQEDLAKHVK"
     gene            complement(80037..80483)
                     /locus_tag="VQ543_000193"
                     /pseudo
     CDS             complement(80037..80483)
                     /locus_tag="VQ543_000193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014295150.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(80559..80993)
                     /locus_tag="VQ543_000194"
     CDS             complement(80559..80993)
                     /locus_tag="VQ543_000194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000927991.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET2610996.1"
                     /translation="MLLVLVSLVHSFGSVSIIAHTIHQKFNLKVPNYRQEEDWARMGL
                     PITRKEISNWHIKASQYYLESLYKLLREKLLEQPLLHADETSYRVLESDSHLTYYWTF
                     LSGKAENQAITLYHHDQRRSGLVVQEFLGDYSGYVHCDMLRQ"
     gene            complement(81069..81920)
                     /gene="rfbD"
                     /locus_tag="VQ543_000195"
                     /pseudo
     CDS             complement(81069..81920)
                     /gene="rfbD"
                     /locus_tag="VQ543_000195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017647909.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose reductase"
     gene            complement(81986..83035)
                     /gene="rfbB"
                     /locus_tag="VQ543_000196"
     CDS             complement(81986..83035)
                     /gene="rfbB"
                     /locus_tag="VQ543_000196"
                     /EC_number="4.2.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000141505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-glucose 4,6-dehydratase"
                     /protein_id="HET2610997.1"
                     /translation="MTEYKNIIVTGGAGFIGSNFVHYVYENFPDVHVTVLDKLTYAGN
                     RANIEEILGNRVELVVGDIADAELVDKLVAQADAIVHYAAESHNDNSLNDPSPFIHTN
                     FIGIYTLLEAARKYDIRFHHVSTDEVYGDLPLREDLPGHGEGPGEKFTAETKYNPSSP
                     YSSTKAASDLIVKAWVRSFGVKATISNCSNNYGPYQHIEKFIPRQITNILSGIKPKLY
                     GEGKNVRDWIHTNDHSSGVWTILTKGQIGETYLIGADGEKNNKEVLELILKEMGQATD
                     AYDHVTDRAGHDLRYAIDASKLRDELGWKPEFTNFEAGLKATIKWYTDNQEWWKAEKE
                     AVEANYAKTQEIITV"
     gene            complement(83045..83641)
                     /locus_tag="VQ543_000197"
     CDS             complement(83045..83641)
                     /locus_tag="VQ543_000197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000131470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase family
                     protein"
                     /protein_id="HET2610998.1"
                     /translation="MTDNFFGKTLAARKVEAIPGMLEFDIPVHGDNRGWFKENFQKEK
                     VLPLGFPESFFAEGKLQNNVSFSRKNVLRGLHAEPWDKYISVADGGKVLGSWVDLREG
                     ETFGNTYQTVIDASKGIFVPRGVANGFQVLSDTVSYSYLVNDYWALELKPKYAFVNYA
                     DPSLGIEWENLEEADVSEADKHHPLLKDVKPLKKEDLE"
     gene            complement(83642..84499)
                     /gene="rfbA"
                     /locus_tag="VQ543_000198"
     CDS             complement(83642..84499)
                     /gene="rfbA"
                     /locus_tag="VQ543_000198"
                     /EC_number="2.7.7.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000676139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase RfbA"
                     /protein_id="HET2610999.1"
                     /translation="MKGIILAGGSGTRLYPLTRAASKQLMPVYDKPMIYYPLSTLMLA
                     GIRDILIISTPQDLHRFQELLQDGSEFGIKLSYAEQPSTDGLAIGEEFISDDSVALIL
                     GDNIYHGPGLSTMLQKAAKKEKGATVFGYQVKDPERFGVVEFDTDMNAISIEEKPEYP
                     RSNYAVTGLYFYDNDVVEIAKSIKPSPRGELEITDVNKAYLDRGDLSVELMGRGFAWL
                     NTGTHESLLEASQYIETVQRMQNVQVANLEEIAYRMGYISREDVLALAQPLKKNEYGQ
                     YLLRLIGEA"
BASE COUNT        24642 a        19292 c        15648 g        25159 t
ORIGIN      
        1 ataagaaaga cgctcatggc atcgctctta aacttctttc tgaccccaat cgtgaacaat
       61 ttcaacacga taatcggcaa gtagaactaa aaatactggc tagacatatt catcgtctca
      121 agaaaaaaca gtctgattgg aaagtacaat acactcgttg tcttgatatc atctttcctg
      181 agttggataa aatcgttgaa aagcattcag aatataccta ccaactcttg acatgctacc
      241 ctaatcctca gaaaaggctt gaggcaggat ttgataagct gatagaaatt aagcgattga
      301 ccgcttctaa aattcaggat atcctctcag ttgcacctcg ttctatcgga acaacatctc
      361 ctgctcgtga attcgaaatc atcaaacatt acaagaggct cattgacaag gcggaaacat
      421 gtgtcaatga cttgatggct gagttcaact cggtcatcac gacggtcact gggattggga
      481 atcgtttaga ggcggtcatt ttagccgaga ttcgaaatat tcatgccttt gataatcctg
      541 ctcaattaca agctttcgct ggactggatt cttctattta tcagtcaggt cagattgatt
      601 tagctggaag aatgatcaaa cggggttccc ctcatctgcg gtgggcactc atacaagctg
      661 ccaaagcatg ccctcgcttt tcacctgctt ttaaggccta tcttaagact aagttagaat
      721 aaggaaaaca ttacaatgta gccatcatcc accttgcaaa aaaacttatc cgaaccctgt
      781 tttatatcct aaaaaagagc tgccatttga cgaacaaaaa gtgatgtaat ttctgaaatt
      841 aacacaggat tacctttgaa aaaatggact ttttcaaggg ctttttgccg tgctctaaaa
      901 tcatcgccaa atcatcaaat tgaaataaga aatagtttag ataaaactat tgacttttct
      961 tatagtttgt cttttttcta tcttccatta tatcatactt tttcagtcta tggtagctct
     1021 ctttaaaagg caccgatact gccgccacct ccgcctccag agaagccacc accagaactt
     1081 ccacttccag aagatacaga gtaggtgctt gctgtatttg cgacactagc ataatggctc
     1141 atttgcgcgc ttgaatgata aaacagactg tgccagccat aagctacata gagattgata
     1201 tctggatttt ccacttgaat ctgatgaacc ttcatcaaat gactaacctt gtccgcatag
     1261 ccaaataagg tcgcatagac caagaggcga ttccagacca caatactttc cagttcagcc
     1321 tgatccaatc gtgcaatctc acgcaacata ttttcaaaac tggtccagag atagtagacc
     1381 tcagctcccg cttcatttag aacaccatca cgattatcta gtcgaagctt ccaataatag
     1441 aaaacagaca aaactaaccc tagaaaacca agtattggca aagggaggta aagatagcca
     1501 tgaacgtcta aactgtacaa gaacaaacca aatccgataa ataggggcag gatagtcaag
     1561 gcacccatac ccacttgcaa ggccttttcc ccaccagtta aaggacgata ataatctggg
     1621 agcccccaga aggaaactcg ttttctcact ccttcttgca tctggttcaa tacctcttca
     1681 aaagaagatt tgagttgaag ccctcttgct tgaatccgtt tttcatcaga aactttggct
     1741 ctacgataaa gactatcaga taccttgtaa tccgcaaaca aattggaaag agtttcttct
     1801 tttttacctg aaaaagctag atttaggcag tctttctcaa agcttgacaa accatcttct
     1861 tttactagcc tcaaaccaac tgcatctcct tctgaaatga tagagacatt cccacggtct
     1921 atcacatcta gcaaggtagc ttgaataagt tgatcaaagg tgaattttcc agctcccttg
     1981 accaagggac tcacttcctc caaggaggtc gagtagactg cttctgataa aaccataggc
     2041 tctaattcca ttggtggttc atagagacga tgatttttgg catatttgac tgaaggagtg
     2101 gtctttcttc tataaataaa atagaagcag acactcaata acaaggagat agaaaggatc
     2161 gaagggagga cccaagtaac aagttgttta ctctgatctt tttctctaac aatcgagtct
     2221 tctatcttat taaactcttc taaacgattc cctttcaatc cctgatccct agcgctagca
     2281 aaatcggtcc gaggccaata ggcatgcaac tcaactccac gcttagccgg aagattgtct
     2341 aaacggatag tataatcaag gttactcttt tcaatcgttc cctctctaaa aagtttccct
     2401 gtatggaaaa agagtttttc agctcccttg tctcccctta catgaaattc aaacttttca
     2461 atagactctg aactatctgt cagaggttgc caatttaatt cagcgatatc atcataaagg
     2521 aaaagtaaat tttttaagtt ccagacgagg tcaacttcaa ctatgtcgcc ctcctgacct
     2581 ggattataga ctctcacagt ataaccatcc gcttcttctg ttacttcgct agtcacatct
     2641 gctagttctg caccgttttt cgcggcctga acctttggat gagggtcaat gtcaaacccg
     2701 ctaggcatct taccagcacg tccaagtccc acgatttgtc ccttaaagtc ctcctcaaac
     2761 tggtaaacta tcttctgtct aaactctgcc gtattatctg catgaatata caaatcccct
     2821 tgataagagt ttatcttgaa atcaatggca aaaacagaga gtggaagaag gcaaaacaag
     2881 cctaacacca gtaagaaaaa agtttttttc atcaactaag cccccttttt atctttctta
     2941 tcattatagc attttttcgt aagtaaaggc ttacttatgt tgaaaaatta cgcatttttc
     3001 gataaaatag gagacagtta ttttttaata gatcagaata ggagaaatca tgagaaaaat
     3061 atacttatct attttcacaa gtctcttgct gatgctagga cttgtcaatg ttgctcaagc
     3121 cgatgaatat ttacgcatcg ggatggaagc agcatatgct ccctttaact ggacccagga
     3181 tgatgatagc aacggagctg tcaaaatcga tgggaccaat cagtatgcca acggatacga
     3241 tgttcaaatc gccaagaaaa tcgctaagga cttaggtaaa aaacctttgg ttgttaaaac
     3301 caagtgggaa ggtctagtcc ctgcccttac ttctggtaag attgacatga ttatcgcagg
     3361 tatgagtcca actgcagaac gcaaacaaga aattgccttt tcgagcagtt actacactag
     3421 cgaaccagtt ttgcttgtca aaaaagattc tgcctacgca agtgctaaat ctttggatga
     3481 ctttaacggt gcaaaaatca cttctcaaca aggggtctac ctctacgact tgattgcaca
     3541 aatcccaggt gctaaaaaag aaacagccat gggagacttc gctcaaatgc gacaagctct
     3601 tgaggctggt gtcattgatg cttatgtttc tgaacgtcca gaagcactga ctgctgaagc
     3661 tgcgaactct aagttcaaga tgattcaagt agaacctggt ttcaaaactg gggaagaaga
     3721 tacagctatc gctatcgggc ttcgtaaaaa tgacaatcgt attagccaaa tcaatgccag
     3781 cattgaaacc atttcaaaag atgaccaagt tgccttgatg gatcgtatga tcaaggaaca
     3841 acctgccgaa gctacaacaa ctgaagagac tagcagtagt ttctttagcc aagtcgctaa
     3901 aattctttct gaaaactggc aacaactctt gcgtggtgct ggtatcactc ttttaatctc
     3961 tatcgtcgga accatcatag gtctcattat tggacttgcc attggtgtct tccgtactgc
     4021 tcctctctct gaaaacaaag ccatttatgg ccttcaaaaa ctagtcggct gggttctcaa
     4081 tgtctacatt gaaattttcc gtggtacgcc aatgattgtt caatcgatgg ttatctacta
     4141 tggaactgcc caagctttcg gtatcaacct tgaccgtaca ctagctgcta tcttcatcgt
     4201 ttcaatcaat accggtgcct acatgactga aattgtccgt ggtggtatcc tggcagttga
     4261 caagggacaa tttgaagctg cgactgctct tggtatgact cataaccaaa ccatgtgtaa
     4321 gattgtccta cctcaggttg tccgcaatat cctaccagca actggtaatg aatttgtcat
     4381 caatatcaaa gatacatctg tattgaacgt tatctctgtt gtcgaacttt atttctcagg
     4441 aaataccgtg gcaacacaaa cctatcaata cttccagaca tttacaatca tcgccgtgat
     4501 ttactttgtc ctcaccttca ccgtaacacg tatcctacgc tttatcgagc gcagaatgga
     4561 catggatacc tacactacag gtgctaacca aatgcaaacg gaggatttga aataatgaca
     4621 caagcaatcc ttgaaattaa acacctcaaa aaatcctatg gacaaaacga agtgctaaaa
     4681 gacatttctc tcactgtcca caagggagaa gttatttcta tcatcggaag ctctggaagt
     4741 gggaaatcaa ccttcctacg ctccattaac ctacttgaaa cgccaactga tggacaaatc
     4801 ctttatcatg gacaaaacgt cctcgaaaaa ggctatgacc tcacgcaata ccgtgaaaag
     4861 ttagggatgg ttttccaatc ctttaacctc tttgaaaatc tcaacgttct tgaaaacaca
     4921 atcgtcgctc agacaactgt ccttaaacgc gaacgcacag aagctgaaga aattgccaaa
     4981 gaaaacctgg aaaaggtcgg catgggagaa cgctactggc aagcgagacc caaacaactc
     5041 tcaggtggtc aaaaacaacg tgtggccatc gctcgtgccc tttcaatgaa tcctgacgcc
     5101 attctctttg atgaaccaac atcagctctc gatccagaaa tggttggaga ggtcctcaaa
     5161 atcatgcaag atctggctca ggaaggcttg accatgattg tcgtaaccca tgaaatggaa
     5221 tttgcccgtg atgtctctca ccgtgttatc tttatggata agggtgtgat tgctgaagaa
     5281 ggtaaaccag aagacctctt cactaatcct aaagaagacc gtacaaaaga atttcttcaa
     5341 cgttatctca tactcaatga aaatcaaaga gcaaactagg cagctagccg caggttgctc
     5401 aaaacactgt tttgaggttg cagatagagc tgacgtggtt tgaagagatt ttcgaagagt
     5461 atcaaataaa aagaaaaggc tgcatcaacc gtgcagtctt tttgctgtcc tcaaaatgaa
     5521 aaggcagatt ctctatctct actacttgaa ggtcaagaat ccaccgttat ccaaagatta
     5581 atcttcaaat ttttcatgat ttttttcata gaaatcaatt aagcctaggg ctgtttcaaa
     5641 tgaaatattt tttacttttg cacgaccctg cgccagagca atgatagaca tttcacgcgc
     5701 attcgtttct ttagagatac ggtagcctgt gattttctta tcacgaaccc agccaacaac
     5761 tgattctact ttttcaaagt ttgacttagc catgtttttc tcctattttc ttctttataa
     5821 tatttaattg tatacgtttt tactactttt gtcaataaaa aaaacatata ttcaacgaaa
     5881 ataattagtt cagaattttc ttacttcctt tttaaatccg ataatatata ggttttgcta
     5941 gcctctacac cataaatatt tgctaataaa aatactgtat tattaccctc ttaaggtgca
     6001 aaattattca agttcttaaa aaatgcttct ctatttccgt aagatagctt atttcttcga
     6061 tttaagaact gaagatgata gttctaacct ttagaaatcc aagccttctc tagctcaaaa
     6121 actcctatct ttcttcctca ataaatcatc tgagagatag gtattcctta tatccttcaa
     6181 attcatcact cctttggata ttgaggtgct agcctagaag cagacacccg attatctaaa
     6241 ccatccttaa tagagatgac aagacagata agctcagtta attacttata tatcttttta
     6301 atatggtata tttgtcaaca aaaagaaatc aaatcatacc ttatactcaa tgaaaatcaa
     6361 agagcaaact aggaagctag ccgcaaattg ctcaaaacac tgttttgagg tttcagatag
     6421 agctaacgtg gtttgaagag attttcgaag agtattaaag acagtatgac tatgcttgtc
     6481 aatagatagg aaatcaaaat gaaggatgga aatctgagcc aaacatcata agtgctataa
     6541 tgaacagaag taagaattgc acgataagtt ttctaaaacc ataggaatcg tcccctttct
     6601 tcatcttcat tatagcacat atacatcagt tgtacaaata atatgatatt tttttattag
     6661 tcctcagaca agcatattat aaagcgtttc attaccattt aagttaatat aagctggatc
     6721 aaaaccttcc attctacgga tcaaacctgc ataatcatgc ttatctgcca aagcgatccc
     6781 aatcaatact gggcctgttc ccttgctagc tcgtttgata tactcaaaac gtgtgatatc
     6841 atcatttggc cccaggatat catttacaaa ctcacgcaaa gctcctggac gctgtgggaa
     6901 attgaccaca aagtaatgtt tgataccatc ataaatcaag gcacgctctt ccatttctgg
     6961 catacggttg atatcattat ttcctccaga aatgatacaa caaatggttt tccccttaat
     7021 atattcagct aaaacctcta aagaggcgat actagccgct ccagcaggtt ctgcgactat
     7081 cccttgctta gagtaaaggt caatcaaggt ttcagaaatc aatccctcat cgacacctac
     7141 caaagtttga atatgttgac gagttgcttc ataggtcaac tgacctacct tttgcacagc
     7201 aatcccatcc gcaaatttat caatttcctt gagtttgact ggacctccag cctcaaaggc
     7261 agctttcatg gaacgcgctc cattcgcctc tactccgata acctcaatct ctggacttgt
     7321 ttccttgata taggtagaaa ccccggcaat gagaccgcca ccaccaacag gaaccaagac
     7381 agcatcaaaa tcaatcgatt cttttcgagc ttcttctaaa atctcataag caactgttcc
     7441 ttgacctgct tgaacatgag catcatcaaa aggatcaata aaggtacgat tttcagagac
     7501 tgtaaattct tgagctgctt tggctgaggc atcaaaggta tctccaacta gtttaatagt
     7561 tacaaaatcc ccaccaaaaa agcgaacctg accaatcttt tgttgtggcg tagtaatagg
     7621 cataaagata gtagcaggaa ttttcatttc attacaagta taggctactc cctgcgcatg
     7681 atttcccgca gaagcgcaga ctaccccacg ttcacgttct tccttgctga gctgggaaat
     7741 ggcataatag gcaccacgaa ttttaaagga gcgaacacgc tgggcatttt cttttttcaa
     7801 ataaatctta gcaccatact tctccgataa ataatgatcg taatccagtg gagtattcac
     7861 aaccacaccg ttcaagacct tgtgagcctt gattatatct tttgaactta acatataaaa
     7921 cctctttttc tataaaaaac agtcactaat gactgttttt tagttattca tctccgaaaa
     7981 cttcagtaac actttcatgg tatttatgag ccatacgaat cgaaaactct ttaggaagtt
     8041 cataacgatt tgtggaaatc caatcatata accattctac caaactttct tcactatcat
     8101 tacgatggaa gataaaatag tttaaaattt ctttatattc tacatcattc aaatccaacg
     8161 tgtctacaaa ttgactacga ggaacaaaat tagaatctaa ttttcttagt tgatctgtca
     8221 attctcccaa ttgtaaatcc aactgaaaaa atagtttttg cagttgccta tcagtttcat
     8281 cacatcctgt cttgatagaa aacaaattgg taatattcat atgatttcaa cccctaaata
     8341 agtacatcta atatcccacg aatagctgaa gctaaagttt tcgcagtcca gtcatttaaa
     8401 cccgattctt tcaatccaga tgcaataatt tgctctattt gatataaacc gccatctatc
     8461 gtctcattta ttctgcgaag aggaccttca atataggata aagcttctcc gaatctaaca
     8521 gctgatttag gtcctaatga tttaccaact atatttgtta atgtttttta tttctcaaaa
     8581 tccatttcgc tatataacga gcagatttag tcgcaccagc tctctcaaac ggagaatgaa
     8641 tttcaagacc ttcttctcta gctatttgtg ccaatttgaa gaattgttca aaggtcatat
     8701 gcaacctacc atcttcaaaa ttagcatcat cataaatgtt aattacagca ttttcatcat
     8761 acgaccaatc tgctttattt tggtctgcta gcactattac cgacggtgta attacattat
     8821 acaactagaa ccaataataa cgatgcaatt tttctcataa tctttttcat aaaatcatct
     8881 ccagcgctat atatttctaa ttagttatag attttgaatg catcatcgtc gtttttacca
     8941 acaaatggca ttgctttacg caattctgca ccaacttttt caatttcaag gttagctgct
     9001 tgttcacggt aagcagtcaa ttttggacgt ccagctttat agtcatttac aaagtcattt
     9061 gcaaatttac cattttggat gtctgccaag acagccttca tattttcttt aacttgttca
     9121 gtgattacac gtggacctga tacatagtca ccgtattcag cagtgtttga aatagattga
     9181 cgcattttct tgaatccacc ttcgtagatc aagtcaacga tcaatttcat ttcgtgaaga
     9241 acttcaaagt aagccaattc tggagcgtaa cctgcttctg tcaagacttc gaaacctgct
     9301 tcgataaggg cagtcaaacc accacaaagt acagcttgtt caccaaacaa atcttcttca
     9361 gtttcttctt tgtaagttgt ttcaagaaga cctacacgag ccgctccaac acctttacac
     9421 cagtccatag caatgttttt agcatttcct gttgcatctt ggtatactgc ataaagagct
     9481 ggaacaccaa atccttcttc gtaagtacga cgtaccaagt gtcccggtcc tttaggagca
     9541 cacatgaaga catctacatc cgcaggaact ttgataaatt caaagtggat gttgaaacca
     9601 tgggcaaatc caactgcgtt tccagcttcc aagtttggag cgatttctgc ttcgtacaat
     9661 tcttgttgaa tttcgtctgg cgccaagatc atgataacat cagccaactt agtagcttct
     9721 actactgtgt aagtatcaaa tccatcttct tttgctttat caaaagattt acctggacgt
     9781 acaccgataa taacgtcacg acctgaatca cgcaagtttt gagcatgcgc atgtccttgt
     9841 gaaccataac cgataacggc gattttttta ccgtcaagtg ctgctacttt aacatctttt
     9901 tcatattcca tttgaactgt catagctttt ctctcttttc tattatttat tgccttttag
     9961 gctggtttaa taaatttaag ttggattttt aatcgcgggt aaatccagtt gcacccgttc
    10021 gagcaatatt gcgaataccg tatgggcgaa tgactcgcaa tagggcttcg ctcttttctg
    10081 catttcccgt catctgaatg gtaatcgagc ttggcgctac gtctaccact gttgcacgga
    10141 aaggttgaat aatcgctaaa atctcagctc tcttctcagc tggcgctgac atcttaacca
    10201 aaatcacctc gcgctccaaa tgaggcttgt ctgtaatatc tcgaatgcga atcacatcaa
    10261 tctgacgatt gagctgtttg atgatttgct ccacttcatc atgagaagca acatcaataa
    10321 taatagtgat acgcgataca ttcggatctt ctgttgctcc aacagagatg ctttcaatat
    10381 taacctgacg acgagatagg acacctgtaa agcgattgag gactcctgaa cgattttgta
    10441 gttttgctgt taacattcta cgcatggaac tgcaccccca acatctcatg attactctta
    10501 ccagccggta ccattggtaa cacctgttcc ttacgagaaa tatctacctc aattagcata
    10561 ggaacatcct cagtgatgac ttcaaggtct tgagccaagg tctcaggatt gtcaaactta
    10621 tagtttttaa taccataagc ctgcgccatc aattggaaat caggaagggt atcaaagacc
    10681 gactctgatg ttctgccttc atagaaggat tcctgccact ggcgaaccat tccaagtgaa
    10741 tgattgttca gcataaccac cttgattggc accttgtaaa tattcaaaat agccaactcc
    10801 tggttggtca tttggaaacc accatcccca acaaacaaga ctacttcctt atctgggtta
    10861 gcaattttag caccgattgc tgctggaatt ccaaagccca ttgttcccaa accacctgaa
    10921 gtcactaact gacgctcatt ttggtaggga taatactgag ctgtccacat ttggtgttga
    10981 ccaacgtctg ttaccacaat ggcatctcca ttcgtcaatt caccaattcg ttcaataact
    11041 gcttgcggtt gaaccacacg ctctttcttg tcataagaac gaacacgatt cttgtcttta
    11101 gtgactttct caatccactt ttcagtattg ttgtgaactg ttggttctgc tagcaacatt
    11161 tgcaaggcct tcttagcatc tccaactaca ggaatgtctg cactgataat cttgccaatc
    11221 tcagctgggt caatatcaat gtgggcaacc ttagcattct tagcgaaagt cttaggattc
    11281 cccgtcaaac ggtcatcgaa acgagaacca atactaatca taaagtccgc ttccgtcatg
    11341 gcaatatttg ctgcgaatga cccgtgcatg cctcccattc caagaaagag tgggtgactc
    11401 gttgcaatcg ttccttgtcc caaaagactg gttaccactg gaatttgata gcgttctgca
    11461 aattcattta gttccgtagc agcctcagca taactaattc caccaccagc taacaagact
    11521 ggctttttag ccttggacaa ttgcttcaag attttcttga tttgcatatc attcggctca
    11581 agagtcggct gataacttgg taaattcact tctggtgaat aaatgaagtc tgtttctaaa
    11641 gcagatatgt cttttggtag gtcaattaca actggccctg gacggcctgt agttgcgata
    11701 tggacagctt ccgtaatgat acgcggaata tcagctgtct cacgaacttg gtaattgtac
    11761 ttagtgattg gcatggtaat tcctacgatg tctgcctcct gaaaggcatc cttcccaatc
    11821 cctgctcgcg ccacctgacc tgtaaagacc aaaaggggaa cgctatcgct catagcatcc
    11881 gcaatccctg taatggcatt tgttgctcct ggtccactag tgacgacggc aacacccaac
    11941 tttccagttg atttggcata accttcagct tcatgcaaac aaccttgctc atggcgccct
    12001 agaatgtggc gaatgccttt aaaattatat atcgcatcat aaaaaggcaa aaccgcacca
    12061 ccaggataac caaagatggt atcaactcct aaatcacgaa gtgtttccaa aactaggtcc
    12121 gaccccgtct taggagattc taaactgatt ttctccattg ttcccctttc tttcctctta
    12181 aaaataactt gttactatca taccattttt tcaaaatttt tcaagataaa agaagaaatt
    12241 ttctgaattt tctattttaa cgtttattta tgaatgttat ttttgttttt attaaaaaga
    12301 taccgatttc atttactaaa aaagaaaaaa gaactgattt ctcagtcctt cattaatctt
    12361 attccacact aaataggtat gggtaaacag gttgttgacc ttggtgaatc tcgacttcaa
    12421 cgtcttcgaa ttcttctacg atttcttgag cgatttcatt ggcaagttct tcgcttccgt
    12481 cttcaccgac atagaaggtt acgatttcac tatcttcatc caacatatgt ttcaaggttt
    12541 cagtcaatgt ttggtgcata tcagggtttg acacaagaat ttttccatcc accataccta
    12601 gattatcgtt ttcatggatt tctaagccat cgatcgttgt atcacgcacg gctgttgtga
    12661 cgcttccgct aacgacatcg ctaagagcag ctgtcatacg ctcttggttt tcttcaatgg
    12721 acttgcttgg atcaaaggca agaagacttg tcataccttg aggaagagtg cgagcctcta
    12781 ccactactgc tggttgctcc aaaacttctg ccgcagattg agctgccatg aagatgttct
    12841 tgttgtttgg caagaagatg atgttacggg cattgacctg ttcaacagcc ttgataaagt
    12901 cttctgttga agggttcatg gtttgaccgc cttcgataac ataatccacg ccttgagaac
    12961 agaagatatc tgctagacct ttaccagcca ccacagcaat caaagcatac tctttttctt
    13021 cagccgactt gataacttga gtagcttctt tctcaacctg tgcttcgtgt tggttacgca
    13081 tattgtcaac ttttaccttg accaagctac catatttgag accttcttgc ataacaagtc
    13141 ctggatcttc tgtatgaaca tggactttga caatttcatc atcgttaaca acgaggagag
    13201 aatccccaag ctcatccaag tagttacgga attcatcgta gtcaaaatct ttagcatagg
    13261 ttggaccttg cttaagagct accatgattt cagtacagta accaaacgtg atgtcctcag
    13321 tcgctacgtg accagctaca gacttatgat gctctacatt gatcatctca ctcatgttgg
    13381 caggagtcgc tacaaagtcc tcagatgcaa tatattcgcc agtaagggct gaaaggaaac
    13441 cttcgtagat gaagaccaat ccttgaccac ctgagtccac aacgccaact tctttcaata
    13501 ctggaagcat gtctggtgtt ttagctagag ctgttttagc accttccaag gctgcgcgca
    13561 tgacttcaac agtgtcatct gtttgctcag cttttttctt agcaccgata gcagctccac
    13621 gagaaactgt caaaatcgtt ccttcaacag gtttcatcac tgccttatag gcaacttcca
    13681 cacctgattg gaaggccaga gccaagtctt gacctgttaa ctcgtcttta tccttgatag
    13741 cttgggaaaa tccacggaaa agctgagacg taatcactcc tgagttccca cgcgcaccca
    13801 tcaaaagccc tttggcaaga atgctcgcta cttctccaac tgtagaagct ggcttgtctg
    13861 caacttcttt agcaccattt tcaatggtca ttcccatatt tgtcccagta tctccatctg
    13921 gaactggaaa gacgtttaat gaattgacat attcagcttg cttattcaag cgagttgatg
    13981 cagcctgcac catttcttga aataagctag tagtaatttt tgacacggtt attctcctac
    14041 aactttgata ttttgaatgt agacatttac agtctgagca gtaattccaa gctggttttc
    14101 caagctaaag gcaacacgct cttgaatgtt ttttgacact tcactaatct ttgttccgta
    14161 gcttaacacg gtatatacat caactgcaat actgccatct tcggctgcct ttacgacgac
    14221 acctttagaa taattttcct tacctagcag ggcttggaaa ttatctttga gggcattttt
    14281 actagccata ccgaccacac caaaaatctc agttgctgct ccacctacga cggttgcaat
    14341 cacttcatct gttagttcga tttgaccatc ttttgtatta atttttacag tcatcctttt
    14401 tacctcaact agttgatact ctattttatc atatttcagc ccaagtgtaa aagcagaatg
    14461 atgtatcagc ggatatttac tctatttttc aaacgatgtt atacccacaa taaaagaaaa
    14521 aagaccctaa ggtctccttt gcttttatta ttaaacgcgt tcaactttac ctgatttcaa
    14581 agcacgagct gaagcccaaa cttttttagg tttaccatcg ataagaacag taactttttg
    14641 aaggtttggt tttacggcac gttttgtttg gttcatcgcg tgtgaacggt tgtttcctga
    14701 tacagtctta cgacctgtaa agtaacatac tttagccatt gtgttttcct cctattagat
    14761 ctaatatagc ggatgtgcta gcaccacata ccgtactatg ttatcacact ttcttgtttt
    14821 ttgcaaggga attggaagat tttttatttg tgtcttaaat caggtcttgc gtgacatttt
    14881 ctgctctcca catgccatcg ttgattaaca gaacaccaga attaaaatta tgtgtataaa
    14941 aatcatctct aactgcagct aagggtatag ccgtcaagtc caaatcccac agctcatcta
    15001 tcgattttct tacaacaata tctgaatcca aatacagtac acgagactcg cttacatact
    15061 ttggaataaa atacctaaaa aagccgcata tgaaagtccc tcaaagggga gacgataacc
    15121 tttcagaata ttactgtcaa tctaaacatt cacaatctca ctattcaaag tctctagtct
    15181 tttttccatc aattggaacc attctcgcgg aaggtcatca ttaaaaacat aaaacttaag
    15241 attataatga tgaacacaaa gagattttat tgttgtttca actttatcca tataagcatt
    15301 atctgcacct aagacaatcg cttttttctc ttttttctct tctttcactt tttatctcat
    15361 ttctttttat tcccatcata tgtttctacg taaccattat tttcgcctat tcgttcgtaa
    15421 aaccatacca gtggagattt tagatgaagt cccattacgg tttacaattt ttacattacg
    15481 acacggagtt ttacaaatcg atttcatttg ccaaacgtag ttagtgaggc agttagctag
    15541 ttcgccaaat agcgactagc gtccaacaat ttggaacttt agttccaatt gttggtactg
    15601 agtcacatct tctcctctaa ctctacgtct ggatacttgt cagcaaacca gcggagggca
    15661 aagtcatttt caaagagaaa gactggttgg tcaaaacggt ctttggctaa gatattgcga
    15721 cttgacgaca tccgttcatc caagtcctca ggcttgatcc aacgaacggt ctttttaccc
    15781 attgggttca taactacttc tgcattgtac tcgccttcca tgcggtgttt aaagacttca
    15841 aactggagtt gacctacagc gcctagcatg tactcacctg tttggtaatt cttataaagc
    15901 tgaacggctc cttcttgcac caattgctca atccccttgt ggaaggattt ttgcttcata
    15961 acattcttag cagaaacttt catgaaaatt tcaggagtaa aggttggcag tggttcaaat
    16021 tcaaacttgt ttttaccaac tgtcaaggta tccccaactt gataagtacc ggtatcgtaa
    16081 accccgataa tatcacctgc cacggcattg atcacattct cacgactttc cgccataaac
    16141 tgggtaacat tagatagttt ggccccctta ccagtacgag ggagattgac actcatgcca
    16201 cgctcaaatt cgcctgatac gatacggaca aaggcaatac ggtcacggtg acgaggatcc
    16261 atgttggctt ggattttaaa gacaaagcct gagaaatcct tgtcataagg atccacaatt
    16321 tcaccgtctg ttttcttgtg accatgtggt tctggagcaa acttgaggaa gatttcaagg
    16381 aaggtctgca caccaaagtt tgtcagggct gaaccgaaaa agacaggcgt caattctcca
    16441 gccagaatag cttcctctga aaactcattc ccagcttcat ttaaaagctc aatgtcatcc
    16501 ttgacttgct cgtagaaagg attgctacca aagagtttgt ccccgtcttc tagactggca
    16561 aaacgctcat cccctttgta aagctctaaa cgttggttat agaggtcata caagccctca
    16621 aaggctttcc ccatcccgat aggccagttc atagggtagc tagcaatgcc caagatttct
    16681 tccaattctt gcaagagatc caaaggctca cgaccgtcac ggtccagctt gttcataaag
    16741 gtaaaaactg gaatgccacg atgtttcaca acctcaaaca atttcttggt ttgagcctcg
    16801 atccccttgg cagagtccac gaccatgacc gcagcatcca ccgccatcaa ggtacgatag
    16861 gtatcttctg agaagtcctc gtgccctggc gtgtctaaga tattcacgcg cttgccgtcg
    16921 tagtcaaatt gcataacaga tgaagtaaca gaaatcccac gttgcttctc gatatccatc
    16981 cagtcagatt tagcaaaagt ccctgttttc ttccctttta ccgtaccagc ctcacgaatc
    17041 tcacccccaa agtagagtaa ctgctcagtg atggttgttt tccccgcgtc cgggtgggag
    17101 ataatggcaa aggtacgacg tttcttaatt tcttcttgaa tattcataag ttctctttct
    17161 ttgattctct atttttcttg tttcaatagc tgagaatgat ttttacattg gattttacca
    17221 ttcctttcaa cattccatta tatcggattt tagcattttt ttcaatttct atttcttttc
    17281 acttccccct cccttattta taggaaaata tggtaaaata gaacagacta aaaatcatca
    17341 tttcacgaaa ggatgcaaga tgaaaattac gcaagaagag gtaacacacg ttgccaatct
    17401 ttcaaaatta agattctctg aagaagaaac tgctgccttt gcgaccacct tgtctaagat
    17461 tgttgacatg gttgaattgc tgggcgaagt tgacacaact ggtgtcgcac ctactacgac
    17521 tatggctgac cgcaagactg tactccgccc tgatgtggcc gaagaaggaa cagaccgtga
    17581 tcgcttgttt aaaaacgtac ctgaacaaga caactactat atcaaggtgc cagctatcct
    17641 agacgatgga ggagatgcct aatgactttt aacaataaaa ctattgaaga gttgcacaat
    17701 ctccttgtct ctaaggaaat ttctgcaaca gaattgaccc aagcaacact tgaaaatatc
    17761 aagtctcgtg aggaagccct caattcattt gtcaccatcg ctgaggagca agctcttgtt
    17821 caagctaaag ccattgatga agctggaatt gatgctaaca atgtcctttc aggaattcca
    17881 cttgctgtta aggataacat ctctacagac ggtattctca caactgctgc ctcaaaaatg
    17941 ctctacaact atgagccaat ctttgatgcg acagctgttg ccaatgcaaa aaccaaaggc
    18001 atgattgtcg ttggaaagac caacatggac gaatttgcta tgggtggttc cggtgaaact
    18061 tcacactacg gagcaactaa aaacgcttgg gaccacagca aggttcctgg tgggtcatca
    18121 agtggttctg ccgcagctgt agcctcagga caagttcgct tgtcacttgg ttctgatact
    18181 ggtggttcca tccgccaacc tgctgccttc aacggaatcg ttggtctcaa accaacctac
    18241 ggaacagttt cacgtttcgg tctcattgcc tttggtagct cattagacca gattggacct
    18301 tttgctccta ctgttaagga aaatgccctc ttgctcaacg ctattgccag cgaagatact
    18361 aaagactcta cttctgctcc tgtccgcatc gccgacttta cttcaaaaat cggccaagac
    18421 attaagggca tgaaaattgc tttgcctaag gaatacctag gcgaaggaat tgatccagag
    18481 gttaaggaaa caatcttaaa cgcggccaaa cactttgaaa aattgggtgc tatcgtcgaa
    18541 gaagtcagcc ttcctcactc taaatacggt gttgccgttt attacatcat cgcttcatca
    18601 gaagcttcat caaacttgca acgttttgac ggtatccgtt acggctaccg cgcagaagat
    18661 gcgactaatc ttgatgaaat ctatgtaaac agccgtagcc aaggttttgg tgaagaagtg
    18721 aagcgccgta tcatgctggg tactttcagt ctttcatcag gttactacga tgcctactac
    18781 aagaaggctg gacaggtccg tacacttatc attcaagatt tcgaaaaagt cttcgcggat
    18841 tacgatttga ttttgggtcc aactgctcca agtgttgcct atgacttgga ttctctcaac
    18901 catgacccag ttgccatgta cttagccgac ctcttgacca tacctgtaaa cttggcagga
    18961 ctgcctggaa tttcgattcc tgctggattc tctcaaggtc tacctgtcgg actccaattg
    19021 attggtccca agtactctga ggaaaccatt taccaagctg ctgctgcttt tgaagcaaca
    19081 acagactacc acaaacaaca acccgtgatt tttggaggtg acaactaatg aactttgaaa
    19141 cagtcatcgg acttgaagtc cacgtagagc tcaacaccaa ttcaaaaatc ttctcaccta
    19201 cttctgccca ctttggaaat gaccaaaatg ccaacactaa cgtgattgac tggtctttcc
    19261 caggagttct accagttctc aataaagggg ttgttgatgc cggtatcaag gctgctcttg
    19321 ccctcaacat ggacctccac aaaaaaatgc actttgaccg caagaactac ttctaccctg
    19381 ataatcccaa agcctaccaa atttctcagt ttgatgagcc aatcggttat aacggctgga
    19441 ttgaagtcga gctagaagac ggtacgacca agaaaattgg tatcgaacgc gcccacttag
    19501 aggaagacgc tggtaaaaac acccacggta cagacggcta ctcttacgtt gaccttaacc
    19561 gccaaggggt acctttgatt gagattgtat ctgaagccga tatgcgttcg ccagaggagg
    19621 cctatgctta tctgacagcc ctcaaggaag ttatccagta cgctggcatt tctgacgtta
    19681 agatggaaga aggttctatg cgtgtggatg ccaacatctc ccttcgtcct tatggtcaag
    19741 agaaattcgg taccaagact gaattgaaga acctcaactc cttctcaaac gttcgtaaag
    19801 gtcttgaata cgaagtccaa cgccaggctg aaattcttcg ctcaggtggt caaatccgcc
    19861 aagaaacacg ccgttacgat gaagcgaata aagcaaccat cctcatgcgt gtcaaggaag
    19921 gggctgctga ctaccgctac ttcccagaac cagacctacc cctctttgaa atttctgacg
    19981 agtggattga ggaaatgcgg actgagttgc cagagtttcc aaaagaacgt cgtgcgcgtt
    20041 atgtatctga ccttggttta tcagactacg atgctagtca gttgactgct aataaagtca
    20101 cttctgactt ctttgaaaaa gctgttgccc taggtggtga tgccaaacaa gtctctaact
    20161 ggctccaagg ggaagtcgct cagttcttga atgctgaagg taaaacactg gaacaaatcg
    20221 aattgacacc agaaaacttg gttgaaatga ttgccatcat cgaagacggt actatttcat
    20281 ctaagattgc caagaaagtc tttgtccatc tagctaaaaa tggcggtggc gcgcgtgaat
    20341 acgtggaaaa agcaggtatg gttcaaattt cagatccagc tatcttgatc ccaatcatcc
    20401 accaagtctt tgccgataac gaagctgctg ttgccgactt caagtcaggc aaacgtaacg
    20461 ccgacaaagc ctttacagga ttccttatga aggcaaccaa aggccaagcc aacccacaag
    20521 ttgcccttaa actacttgca caggaattgg cgaagttgaa agaaaactag acagaacaaa
    20581 accagcccta aggttggttt tttcttctct accaactccc aataactatt ttggctttat
    20641 ttccagagta ttttatggta aaatgaagag taataatatt tattaaagag gtaaaaacat
    20701 gattgaagca agtaaattaa aagctggtat gacctttgaa acagctgacg gcaaattgat
    20761 tcgcgttttg gaagctagtc accacaagcc aggtaaagga aacacgatca tgcgtatgaa
    20821 attgcgtgat gtccgtactg gttctacatt tgacacaagc taccgtccag aggaaaaatt
    20881 tgaacaagct attatcgaga ctgtcccagc tcaatacttg tacaaaatgg atgacacagc
    20941 atacttcatg aatacagaaa cttacgacca gtacgaaatc cctgtagtca atgttgaaaa
    21001 cgaattgctt tacatccttg aaaactctga tgtgaaaatc caattctacg gaactgaagt
    21061 gatcggtgtc accgttccta ctactgttga gttgacagtt gctgaaactc aaccatctat
    21121 caaaggtgct actgttacag gttctggtaa accagcaacg atggaaactg gacttgtcgt
    21181 aaacgttcca gacttcatcg aagcaggaca aaaactcgtt atcaacactg cagaaggaac
    21241 ttacgtttct cgtgcctaat ctctagaaag aggtcattct atgggaattg aagaacaact
    21301 tggcgaaatc gttatcgccc cacgtgtact tgaaaaaatc attgctatcg ctactgcaaa
    21361 ggtagagggt gttcactctt tttcaaacag atcagtgtct gatacccttt caaaactttc
    21421 actcggccgt ggcgtttatc ttaaaaacgt ggacgaagaa ctcacagcag atatctatct
    21481 ctaccttgag tacggagtaa aagttcctaa ggtagcggtt gctatccaga aagctgtcaa
    21541 agatgccgtc cgtaatatgg ctgatgtaga actcgctgct atcaatattc acgttgcagg
    21601 tatcgtccca gataaaacac caaaaccaga attgaaagat ctatttgacg aggacttcct
    21661 caatgactag tccactatta gaatctagac gccaactccg taaatgcgct tttcaagctc
    21721 tcatgagcct tgagttcggt acgaatgtcg aaactgcttg tcgtttcgcc tatactcatg
    21781 atcgtgaaga tacggatgta caacttccag cctttttgat agacctcgtt tctggtgttc
    21841 aagctaaaaa ggaagaacta gataagcaaa tcactcagca tttaaaagta ggttggacca
    21901 ttgaacgctt aacgctcgtg gagagaaacc tccttcgctt gggagttttt gaaatcactt
    21961 catttgacac tcctcagctg gttgctgtta atgaagctat cgagcttgca aaggacttct
    22021 ccgatcaaaa atctgcccgt tttatcaatg gactgctcag ccagtttgta acagaagaac
    22081 aataaaaaga aaaagtgttt gatagatatc aaacactttt tctttgcctc ccactatcta
    22141 aaaaaatgat aatagatata attgtaaaca aaaatccaga taggttttgc atgattgaga
    22201 aagttaaaaa aactatggca gagaatcgtt aatctcagat tgtcggtaga acgataaaca
    22261 agggcaaaaa agaaaccaat cagactataa tataataaac taattggatc tctgtgagat
    22321 agtatcaaat ggctaatccc aaagataagg cctgataaga tgacatctaa atagtacttt
    22381 gacttaggaa agaaggtatt cataaaatac cctctatcaa gagtctcctc aaaaacagga
    22441 ccgatgatta caagcaggac aaaagataag atagtcgata aaaaggttgg ttgtccattt
    22501 gaaagaacca cggtaaaata ctcatcatga atattcctat ggttaatcaa atgagcatag
    22561 cgtgcctaaa aattaccgag aatctgataa accacataag ttgcaaataa ggagaagaca
    22621 aatgaccagt cccagctctt tttctttttt aacctccaaa ttaatagaaa aggaaacttc
    22681 ccactaatcc cactgttaaa ataagagaat agacatcagc tcctaaccct aaaatgatcg
    22741 tcacatacaa tccaattgtt tgtggtaaat aggtagatag taaaataata agcaaaaata
    22801 ttccaaattg tcttagtttc tttgtgtttc tcatcgtact tttttgaaag attaccctgt
    22861 tcggaagccg tacttccaag catctatata agaattaagt gccccttgcc tcatataggg
    22921 agcaaattct ctataatata accatctact atatccatct tcccaaacag caagaccacc
    22981 tgaagtttgc tccaagtcct cagttgaaag aactgtaaat gtttctgtac ctgtcattgc
    23041 aagtaccttc ttaaaataga ttgttgtagg ctcacattta tagtatattt ctttttttgt
    23101 ctattttata gtctatctcc tcaactggca atttttcgac ctgaattgca tttttccata
    23161 aaaaatgaga cctttctagt ctcatttagt cattcttagt attttctaaa tcgttgatag
    23221 cgttcttcca gcaactcttc tagcggtttt tgtgaaagtc tagccagctc cgtttggagt
    23281 tcttttttga cactcttaat tagttcttta ctagaaagtc ctacttcaga aatcacctta
    23341 tccaccacgt ccatttctaa cagttcatgc gaagtgattt tcatcagttc tgctgcttcc
    23401 atggcgcgag taccgtcctt ccataaaatg gaagcaaagc cttctggact gagaatggca
    23461 tagatagaat tttccagcat ccagacacgg tccgcgacag ctagagccag agccccgcct
    23521 gaaccacctt caccgataat aatggcgata ataggaactt tcaggtcact catttccatg
    23581 agattgcgag cgatagcttc cccttgacca cgttcttccg ctccgacacc aggataagca
    23641 cctgctgtat tgataaaggt cacaactgga cggccaaatt tctcagcctg tttcatcaac
    23701 cgcagtgcct ttcggtagcc ttctggatgt ggttggccaa aattccgttt gaggttgtct
    23761 tgcaaactct tgcctttttg gataccaacc actgttacag cttggtctcc aagccaacca
    23821 ataccaccaa caactgcacc atcatcacga aaagaacggt caccatgtaa ttggataaat
    23881 tcatcaaaaa tgcctgtcgc aaagtccaag gttgtcaagc gactctgctc acgcgcttct
    23941 ctgactattt ttgcaatatt catctaggac tccctccatg caatctgact aggctagcaa
    24001 tcgtatctgg taagtctctt cttttgacaa tagcatccac aaagccatgt tctaatagga
    24061 attctgcctt ttggaaatcc tcaggcaagc tttcacgaac cgtattttca atcacacgac
    24121 gcccagcaaa accaaccaag ctctgtggtt cagccagaat gatatcgcct tccatagcga
    24181 aagaagctgt cacaccacca gtcgttggat ctgtcaaaat ggtcaggtaa aagagaccag
    24241 catttgaatg gcgtttaacc gctgcagaga tcttagccat ctgcatgaga ctcatgattc
    24301 cttcctgcat acgggctcca ccagaggctg tgaataggac aactggtaat ttttcgacag
    24361 tcgcatactc aaacaaacga gtgatttttt cacctacaac cgtacccata gaagccatga
    24421 taaaattaga atccataatc ccaagagcca cagtctgacc tttaataaga gcagttcctg
    24481 tcacaacggc ttcatgcaga cctgtttttt cacgcataga tgccagtttc ttttggtaac
    24541 cagggaaatg caagggatcc ttgctttcaa tccctgtaaa caattctttg aaggttccca
    24601 tatcaatcgt caaagccaag cgttcttggg cagaaatacg aaaggtatag ctacagtgcg
    24661 gacagatacg ttcacttccc agatccttct gatagatggt atgcttacag cctggacact
    24721 gggaaaataa ttcatctgga acctctggct tagcttgagg tttttcccta accgaacgat
    24781 tgggattgat tcgaatatac ttatcttttt tactaaatag agccattgat tccccttttc
    24841 ggtttaaact cttaaagtca ttttattctt tttcttgata tttaggtaag aaggtttcca
    24901 tcaagaagga agtatcataa tccccagcaa tgacattgcg atctgaaatg agatcaagct
    24961 ggaaatctgc attggtctgc actccttcaa tctctaattc atagagggca cgttgcattt
    25021 tcatcaaggc gtcaaaacga ttttcgccgt gtactatgat tttggcaatc atactatcat
    25081 aataaggcgg aatggtataa cctggataaa ctgctgaatc cacgcgcaag ccaactccac
    25141 cacttggcag atagagatta gtaatcttac ctggacttgg agcaaagtta aaggctgggt
    25201 tttctgcatt gatacgacac tcgatggcat gaccgcgtag gacaatatct tcttgcttaa
    25261 cagacaaagg ctgacctgcc gcaatgcaaa tctgttcctt aacgatatca acacctgaaa
    25321 caaactctgt tactggatgt tctacctgaa cacgagtatt catctccatg aaatagaaat
    25381 tgctacttgc ttcatcaaga agaaattcaa tggttcctgc attctcatag ccaacaaact
    25441 ctgccgctcg aacagcagca gcacctattt catgacgcag cgtttttccg attgcaatcg
    25501 agggactttc ttccaaaacc ttttggttat tcctttgaag agaacaatcc cgttcaccca
    25561 agtgaatcac atgtccatgc tcatcaccta ggatttgaac ctcaatgtgc cgagctggat
    25621 agataacccg ttctatgtac atggcaccat tgccataatt ggccttggcc tcactagagg
    25681 cagtttcaaa ggcagaaacg aggtcatctg gtttttcaac cttacgaatc cctttaccac
    25741 ctccacctgc tgaagccttg agcataacag gatagccaat tttttcagca acaatcaaag
    25801 cttcttcaga gttatgcact tctccatctg aacctggtat aacaggcaca cctgctttaa
    25861 tcatctgagc acgcgcattg atcttatccc ccatcatatc cataacatga ccagatggac
    25921 cgataaactt gatacctact tcttcacaca tggtcgcaaa tttggaattt tcactgagaa
    25981 atccaaaacc agggtgaata gcttctgcct cagtcaagac tgcagctgat agaactgcat
    26041 taatattgag ataagactct gttgccttgc caggaccaat acaaactgct tcatctgcca
    26101 acagcgtatg aagagcttcc ttatcagcag ttgaataaac cgctaccgtc gcaatcccca
    26161 attcacgtgc cgcacggata atacgaaccg caatttcacc acgattggca attaaaattt
    26221 ttcgaaacat ggagaacctc cttagttccc aattgcaaaa gtaagggtac cactggctgc
    26281 aagcttgcca tccacttcag cctttgcttc aaccacagct atggtgccac gacgttttac
    26341 aaaagtcgct gtcataacca attggtcgcc tggtacaact tgcttcttga acttaacctt
    26401 atccatacca gcgtaaaaga ccagttttcc tttattttca ggttttgata actccaacac
    26461 accagcagtt tgcgccaagg cttccataat cagaacacct ggcataactg ggtattgagg
    26521 aaagtggccg ttaaagaaag gctcgttgat ggtcacattt ttgatagcaa caatggtatc
    26581 ctcgctcacc tccaagacac ggtccactag aagcatagga taacggtggg gaagggcttc
    26641 tttgattcct tgaatatcga tcatttgata cgtaccaatc ctttaccaaa ctcaaccatt
    26701 tcttcgttag agacgagaat ttccgttacc acaccatcct taggagctgg gatttcattc
    26761 atgactttca tggcttcgat aattaccaat gtttgacctt ttttgacact atcaccaact
    26821 gtaacgaagg caggtttatc tggtccagca gccaagtaaa ccactccaac aagtggactc
    26881 tctacaagat ttccctcact agccacactt gcttcagctg gagctggaac ttcttctgct
    26941 acagtctctg ctggagcaga tgtaggagct actggactcg gtgttgctag aacgggtgct
    27001 ggagcgactt gagttgcaac ttcaggcaca ggtctcgctt cattcttgct aaactgcaac
    27061 tcatccgtcc catttttata agaaaattct ctcaaacttg actggtcaaa ttgagtcatc
    27121 aagtctttaa tatcgtttaa attcatactt atctattctc ccaacgtttg aaagcaagaa
    27181 ctgcattgtg gcctccaaaa ccaaaagtat ttgaaatagc gtatggaatt tctttctcca
    27241 agccttgtcc ataaacgaca ttagcttcga tataatctga tacttcactt gtcccagctg
    27301 tcattggtac aaagttatga cgcatagctt cgatggtgac gatagcttct actgcacccg
    27361 cagcccccag caaatgtcct gtaaaagact tggttgatga tacaggtact tccttaccaa
    27421 gaacagctac gatagcacca ctttctcctt tttcattggc aggagttgac gttccgtgag
    27481 cattgacata ggctacttgc tctggagaaa tctcagcttc ttccaaggct agtttgatgg
    27541 ccttgatagc tccctgacct tctggatgtg gagaagtcat gtggtaggca tcacaagtat
    27601 ttccgtaacc aaccacttca gccaggatag tagctccacg tttttcagcg tgttcaagac
    27661 tttctagaac caacatccct gaaccttcac ccataacaaa cccattgcga tccttatcaa
    27721 atgggatcga agcacgagtt ggatcctctg tagtagagag agctgttaag gcttggaaac
    27781 cagcgatggc aaaaggtgtg atagaagctt ctgttcctcc caccaacatc acatcttgga
    27841 aaccaaactt aatggagcgg aaggcatccc caatcgcatc atttgatgaa gagcaggcag
    27901 tattgataga tttacaaaca ccgtttgcac caaaacgcat ggctacattc ccagaagcca
    27961 tatttggtaa agcttttgga agagtcattg gtttgacacg tttgggtcct ttttcatgaa
    28021 ggcgaagtac ctgatcttca atttccttga ttccaccaat accagatgca acgataacac
    28081 caaaacgatc cctattaaga gcctctacat caagattggc atgatttaca gcctcttggg
    28141 ctgcatacaa ggcatataaa gaatagttat caaaacggtt ggtatctttt tttacaaagt
    28201 atttatcgaa cggaaaatct tggatttctg ccgcattatg cacatcaaag tcactatgat
    28261 caaattttgt aatgccacca atgccgattt tcccagttgc taaactattc caaaattctt
    28321 ctggtgtatt tccgattgga gatgttactc cataacctgt taccactact cgatttagtt
    28381 tcattctttt cacctctagc tttcgctaca tacttaagcc accatcaatg gcaatcactt
    28441 gaccagttag ataatcttgg cctgctaaaa atactgtcaa atctgcaacc tgctctgcct
    28501 gcccaaattc tttcatcgga atctgagcta gtgtagcttc cttaatctta tctgataaga
    28561 tagctgtcat atcagactca atcattcctg gagcaatcac attgactcgt atattccgac
    28621 tagcgacctc gcgtgccaca gacttggtaa agccaatcaa gccagcctta gaagcagcat
    28681 agttagcttg accaatattc cccatcaaac caacaacact agacatatta atgatagcac
    28741 cttctctggc tttcatcatc ggtttcaaga ctgattgtgt catattaaag gcaccagtca
    28801 gattgacctt gagcactttt tcaaaatctg cttctgtcat cttgagcata agagtatctt
    28861 gggtaatccc tgcattgttg accaaaacat ctactgaacc cagttctgca atagcttgat
    28921 caatcatacg cttagcgtct gcaaaatctg atacatctcc tgaaatggga accaccttga
    28981 taccatagtt tgaaaactca gcgagcaatt cttctgagat tgccccacga ctgtttaaga
    29041 caatgttggc tcctgcttga gcaaacttgt gggcgatggc aagaccaatt ccacgactcg
    29101 aacctgtaat aaagatattt ttatgttcta gtttcatttt tttcctttca aaacttctac
    29161 ttattttagt ctatttttct aaaagtgcta ctaaactcgc ttgatcttcc acatgagcta
    29221 agtgagcagt ttgatcaatt tttttaacaa aacctgacaa gactttcccc ggtccaatct
    29281 cgataaagtt gcttatgcct gcttcttgca tgaccccaat actttcatag aaacgaacgg
    29341 gttccttgac ctgacgcgtc aagagctgag caatgtcctc tttttgcatc acagcagctt
    29401 ctgtattgcc gactagggga caagtaaaat ctgaaaaact tacctgagct agagtttcag
    29461 ctagtttctg gctagcaggc tcaaggagag cggtgtgaaa gggacctgac accttaagag
    29521 gaatcaagcg tttggcacct gcttcttgca aaagttcaac cgctcgatca actgcaacca
    29581 cttctccagc aatgacgatt tgtgcaggtg tgttatagtt ggctggagta accactccaa
    29641 gttcagaagc tttttgacag gcttcttcaa tgacctctac tggcgtattg agaactgcta
    29701 ccatcttgcc agagtcagca ggagccgctt cttccatata ggctccacgc ttagctacca
    29761 aggcaaccgc atcttcaaaa tccaaggcgc cgcttgccac caaggcagag tattctccaa
    29821 gagacaaacc agcaaccata tcaggctgat agcccttttc ttgcaataaa cggtagatag
    29881 caaccgaagt cgctagaatg gctggttgcg tatagcgggt ctgattgagt ttgtcttctt
    29941 ccgtatcgat gagataacgt aaatcataac cgagcacctg actcgctcga tcaatcgttt
    30001 ctttaacaat cggatactga tcatagaaat cccgtcccat ccctagatac tgggcacctt
    30061 gaccagcaaa taaaaaggct gttttagtca tttcttacaa ctcctgccca gcgagaggct
    30121 tcttcttgaa ttttcttagc ggctccgtaa tacaaatctt ttaggatttc ttcagctgtt
    30181 tcttctttag aaacaagccc tgcgatttga cctgccatga cagagccacc ctccacatca
    30241 ccgtgaacaa ctgctttggc tagggcacct gctcccattt gttcaaagat ttctaaatca
    30301 ggatcttcct gcttaaaggc atctttttca gccagttcaa aatctctagt caactgattt
    30361 ttaatagcac gaacagcatg accaaagtgc tgagctgaaa tcgtagtatc aatatccctt
    30421 gcttttaaaa ttttctcttt gtagtttgga tgggcattcg actcttttgc aactacaaac
    30481 cgtgtcccca cctgtacagc ctctgcacct agcataaagc cagccgcagc accttcacca
    30541 tccgcaattc ctcctgcagc aataacagga atagatatag ctgtggctac ctgtcgcacc
    30601 aaggtcatgg ttgttaattt accgatatgc cccccagctt ccattccttc tgcaataaca
    30661 gcgtctgcac cgattttttc catgcgttta gctaaagcga cactaggaac aacaggaata
    30721 acgattatcc cagcttcatg gaaacgttcc atatacttgc ttggatttcc tgctcctgtt
    30781 gtgacaactt taacaccttc ttcaataacg agatccacga tatcttccac aaagggagat
    30841 aagagcatga tgttgacccc aaagggttta tcagtcaatg atttgatttt atcaatattg
    30901 gccttgacaa cttctttcgg ggcatttccc ccaccgataa ttcctaatcc tccagccttg
    30961 gaaacagccc ctgccaaatc accatcagca acccaggcca tccctccttg gaaaatagga
    31021 tagtcaatct tcaataattc tgtaatacgc gttttcatag tgcctccaac cttccttgct
    31081 tacgtaatag ttcgatttca ccataatttg acagtcaaac tattacctaa acaagaggga
    31141 gtgggtttct ccctactcct tctactaata ttctgcttat tttgcttgct cttcaacgta
    31201 agcaaccaag tcaccaactg ttttcaagtc attttctgct tcgatttgga tatcaaaagc
    31261 atcttcgatt tctgagatta cttggaacaa gtccaatgaa tctgcgtcca aatcatcaaa
    31321 agttgattca agtgttactt ctgatgcgtc ttttccaagt tcttcaacga taatttcttg
    31381 tactttttca aatactgcca tgataggact cctttaaaat aaatagtttt tttataacaa
    31441 tgtgttcacc acatgattac ctaaattgta agaatgagcg tgccccaggt caagcctcca
    31501 ccgaagcctg atagaagaac agtttggcta ccatctaaag ggatgagacc ttgttctaca
    31561 cactctgaaa gtaaaatcgg gatactggct gcactggtat tgccatattc catcatatta
    31621 gctggaagtt tggctcggtc aacaccaatt tttctagcca tcttatccaa aatacggtta
    31681 ttggcttgat gaagtagcag ataatccaag tctgtcacct ctataggaga ttcatcaata
    31741 gtctgcttga tagacttggc tacatctcga atggcaaaat caaagactgt gcgtccatcc
    31801 atcttcaaaa atgaatctgc actttcttga tctgaaaatg gagaatgcaa acctgaatgc
    31861 ccataagtta aacactcgct gcgacttcca tcgctattga gactctcagc taagaaatgc
    31921 tcttgctcgc tagcttctaa caagacacca ccagcaccat ctccaaacaa cacagctgtt
    31981 gatcgatccg accaatcgac tgccttagag agggtttcac taccaatcac caagcctttt
    32041 tgaaagcgac cagaagcgat aaacttttca gcagttgaaa gagcaaatac aaatccactg
    32101 caagccgcgg ttaagtcaaa agcaaaggct ttattagcac caatattagc ttgaacacga
    32161 gcagctgtag agggcatcat cgaatctgga gtaatggtag ctaggatgat aaaatccagt
    32221 tcttctcctg ttattccagc ttttgccatc agtttcttag caacctctgt agccaaatca
    32281 ctggtagatt ctgttcttga aatatgcctt tgtcgtattc ccgttcgact tgaaatccac
    32341 tcatcattgg tatccataat ctgagccaag tcgtgatttg taaccacttg ctctggcaca
    32401 taatgagcaa cctgacttat ttttgcaaaa gccattattt caaatcctcc aaaaattggt
    32461 aaagattagt caaaccttta cccatgacag caatttcttc ctcgctcatg ccatcaataa
    32521 ttttttctac catggccttg tggaagcgtt tatgcagtct atgaatcaag cgacccttct
    32581 ttgtcaaatg cagatgcacc acacgacgat cctgttctga ccgaactcgc tcaatgtagc
    32641 ccttacgctc taaattgttc aaacttgtcg taacagttcc aagagttacc atcaactctt
    32701 ttgacacttg acttggagtc acatctggag ccttaccgat gacatcaatc gtatgcattt
    32761 ctttgatgga gatatcctta aaacgactac ctctcaagtt cacttcctca attacaagga
    32821 cattgttaaa tatagatgtt aaatattcat tgattcgttg gtagtccatt tttcatatcc
    32881 ctccttcttc aaaaaacttt tacaatcaaa acatttgaca gaaagaatta tatcaaaatt
    32941 caaagaatga tgcaagtatt ttttattttc ctgtaaattt aggtcttctt ctctccgaat
    33001 gagctcgcac tccttctttg aaatcctctg tttgagctaa ggatttctgt aggttcagtt
    33061 ctaaagtagc gtaaccctgc cagtctttaa attggctctc ccaaaccaac ttcttaatgg
    33121 cagcatagga attacttgaa gcacgtctta attttttaag aagctgttct ctcgtctttt
    33181 caagtttttc agcttcagaa acgcggtaaa ccaaccccca ttctagggct ttttctgccg
    33241 ttaaagcctc tcctgtcata gctaattgag cagcacgcgt cacaccgata ctgcggctca
    33301 agagatgaat tccccctgca tctggagcca aaccaacacc aacaaaggct tggataaact
    33361 tagccttatc cgtcgccaaa cagaaatctg ccgcaacagc catattcgct gcggcacctg
    33421 caacagcacc gtcaacttcc attaaaacag gtttggctat ttgcttgatt ttataagaaa
    33481 tcgtattgac caactctgcg atttttgtca atgatggaat atcatcctca tccactgccc
    33541 gcttcatctc taccaaatct cccccaactg agaagacctt tccattggca ttgattaaga
    33601 taaaatgcac agctggattt tcttctgcca aagtcagagc ttctaaaatc tcctcacaca
    33661 tgggaatatg aaaaccattt gcgacctcag gacggttcaa ggtaaggatt gccaagtcct
    33721 cttcaagctg ataaataatg tgttccatca gggctccttt ttattttata agcagtttat
    33781 actcttcgaa aatctcttta aaccgcgtca gcttccatct gcaacctcaa aacagtattt
    33841 tgagctgact tcgtctagct tcttagtttg ctctttgatt ttcattgagt gttaaattat
    33901 ttcactgtca aagtatatct tttttaggag cagaaagcaa gaaaaaatcg actgaaagtg
    33961 tctcagccga taagaaaggc tcgctttagg ctagaaagca tcttattttc ttcattgaaa
    34021 aaagcctttc tttctgctat aatcgtataa aatacttact ttaggagttc ttatgaaagt
    34081 tgttaaattt ggaggtagtt ctcttgcctc tgctagtcaa ttagaaaaag ttttaaacat
    34141 cgtcaaaagc gattcagagc gtcgttttgt agtcgtttct gcgcctggta aacgcaatgc
    34201 tgaagatact aaggttacgg atgccctgat taaatactac cgcgactatg ttgcgggtaa
    34261 cgatattagc aagagccaaa gctggattat cgaccgctat gctgctatgg ttagtgaatt
    34321 gggactaaaa ccagctgtgc tagaaaaaat ttctaaaagc attcacgcct tggccactct
    34381 tcctattgaa gaaaatgaat ttctctacga tactttccta gcagccggtg aaaataacaa
    34441 tgccaaattg attgctgcct actttaacca aaatggtatc gatgcacgct atatgcaccc
    34501 tagagaagct gggattgtgg tcacaagtga acctggtcac gctcgcatca ttccatcaag
    34561 ttatgacaag attgaagaat tgacaaacac caatgaagtc cttgtcattc ctggtttctt
    34621 tggtgtcact aaggaaaatc aaatctgtac tttctcacgt ggaggttctg atattacagg
    34681 ttctatcatt gctgctggtg tcaaagctga cctctatgaa aactttacgg acgttgatgg
    34741 tatctttgca gcccaccctg gtattatcca ccaaccacac tcgattcctg agttgaccta
    34801 ccgtgaaatg cgcgagttgg cctatgcagg cttctcagtc cttcatgacg aggctcttct
    34861 tcctgcctac cgtggaaaaa ttcctctggt tatcaagaat accaacaacc ctgaccatcc
    34921 aggtactcgt atcgttctaa aacacagtaa tgatgaattt ccagttgtgg gaattgctgg
    34981 tgactcaggc tttgtcagca ttaacatgtc gaaatacctc atgaaccgtg aggttggatt
    35041 tggccgcaag gttctgcaaa tcctggaaga acttaacatc ggttgggaac atatgccaac
    35101 aggtatcgac gatctttcta tcattctccg ttctcgccaa ctaactccca tcaaggaaga
    35161 agaaatcctg cgtcagttgg ttcaaaaggc taaagtagat catgcagaaa tcgaacacga
    35221 cctttctatc attatgattg ttggtgaaaa aatgaagagc catatcggag tgactgctac
    35281 tgcgacacgc gctctatctg aaaacaaaat caacatccag atgatgtctc aaggttctag
    35341 tgaagtttct attatgtttg ttgtcaataa agaccaagag aaagcagcaa ttaaagccct
    35401 ctacaatgcc ttttttggag aaagtaagga agactaagca tggcccaatc acttaacaaa
    35461 acagtactcc tcagtacgac aggcacttcc tacctctcta tcgctgggaa agttgggaaa
    35521 ttccttgtcg gagatcaggc tttggaattt tacccagatg tcaatgtcga acaatttatc
    35581 cagattcctt ggagccatat caatcagatt ggagccaatg tcactggacg caaaatcagc
    35641 cgccacttcg aagtctttac agacaaagga aaattcctct ttgcttcaaa agactcaggt
    35701 gccattctca aaattgcacg cgaaaaacta ggcaatgaca aggtcgtcaa acttccgacc
    35761 ctgattcaga caattagcca aaaatttaaa aatctatttg caaaaaagta gaaactttag
    35821 tataatcata gcaacggata agtaggttat cttcttcttt cagaaagtct gcgggtactg
    35881 cgagcagata ggggggatag gtgaaattct accgttagta acaattacat acacaatcaa
    35941 gtgcacacct gtgaagttgg atggaaccgt ggccctgcca ctccaacgtt ttgtcaggcg
    36001 tgcttttttc ataaaggagt tcttatgtta gatatcaaac gtattcgtac agattttgaa
    36061 gctgtcgcag aaaaattagc tacacgtggt gtagatgctg ctgtcttgaa tgaaatgaaa
    36121 gaaatcgatg ctaaacgtcg taacatcttg gtcaaggttg aaactctcaa agcagaacgt
    36181 aacacagttt ctgctgagat tgcccaagct aagcgcaaca aggaaaatac agatgacaag
    36241 attgctgcca tgcaaaatct atctgctgag gttaaagcct tggatgctga attggcagaa
    36301 atcgatgcta aattgacaga atttacaacg actcttccaa atatcccagc tgacagcgtt
    36361 cctgttggga ctgacgaaga cgacaatgtg gaagttcgcc gttggggtac tccacgcgag
    36421 tttgacttcg aacctaaagc tcactgggat ctcggtgaag accttggtat ccttgactgg
    36481 gaacgcggtg gtaaggtaac aggcgctcgc ttcctcttct ataaaggcct cggtgctcgt
    36541 ttggaacgtg ctatctacaa ctttatgttg gatgaacatg gaaaagaagg ctatactgaa
    36601 gtcatcacac cttacatagt caaccatgat tctatgtttg gtactggtca gtatccaaaa
    36661 tttaaggaag atacttttga actcagcgat accaactttg tcttgattcc aactgctgaa
    36721 gttcctctga caaactacta ccgtgatgaa atcttagacg gcaaagatct tccaatctac
    36781 ttcactgcca tgagtccgtc attccgttct gaggctggtt ctgccggtcg tgatacgcgt
    36841 ggcttgatcc gtttgcacca attccacaag gttgaaatgg tcaaatttgc caaaccagaa
    36901 gaatcttacg aagaattgga aaaaatgaca gccaacgctg aaaacattct tcaaaaactc
    36961 aaccttccat accgtgtcgt tgctctctct actggagata tgggcttctc agctgcgaag
    37021 acttacgact tggaagtgtg gattccagca caaaacaatt accgtgaaat ctcaagctgt
    37081 tcaaacacag aagatttcca agcccgtcgt gcccaaatcc gttaccgtga tgaagcagat
    37141 ggcaaggtga aactccttca taccttgaac ggctctggac ttgcagttgg acgtacagtg
    37201 gctgcaattc ttgaaaatta ccaaaatgaa gatggttctg tgaccatccc agaagcactt
    37261 cgtccataca tgggtggagc tgaagtcatc aaaccataaa aaataaggtt tagctatttc
    37321 tagctagacc ttttttcgta accaaatcag ataagcacct agtacaaaga ataaaatagt
    37381 taggcatata atggtttcag ccaataccag gtaatccaga aatggaagtt tcaaaattcc
    37441 ctgagccatc ttgagcgagg tcgctgtgat aatggttggg aaggtgaggg ctgagaaggc
    37501 tggttgaaaa ccttgtttta aaatgttggg cagacgagtt aaaacaaaga aaaagaagga
    37561 ttgagaagcc aaaatcatga caatcaagac ccaagtcggc aggctggttc ctcctactcg
    37621 aactagagaa gccaagagta gagagaaagg agcacagtag attccttctt gtccaagcaa
    37681 ggctagtggg agtggatgtt tctttaaatc gctataaata aggggataga gatagaaggt
    37741 caagagaaaa ccaaaactca aggtcgcata ggcaatttcg ataataccta ccagaggata
    37801 ggtcaaggca gccactgcta tccccacata gagaaccgtc caacttggag tggcatgaac
    37861 cctccgccct gaacaagcaa acttgatggt aaaaccagca atcaaggtca aatccaagag
    37921 aaatgaaaac caccaaatcc cttgtgctac caaaggaaga taagagaata cgcgaaagac
    37981 ataggtcgat aaaatcatcc cagccatagg aaaggttgcc attcctgaca aaagaggggg
    38041 cttggtcaat tcttgcttgg tttctttcca attaaagaga tgcagaatta gaaagtaaat
    38101 ccataaaacc aaaccagtca gactaaaaag atgggataga accggcaacg tatctaaaat
    38161 aagatttcca gctcctgcca aacctagcaa acaacctgaa aatactaagg ggagtttttt
    38221 catcctaacc tccaataatc atgttagttt cagtataaca taaaagcgct taaatgagga
    38281 tttaaaaaaa cgaagtccgc ttatttcaga cttcatttta ctcagatatg aattaggcat
    38341 aaggttgcaa ttctggatta attggtgtat tagctaagtt gttggcatag ttacagagga
    38401 ttgctaggct gacaccaaaa accacatcca aggcattttg ttgagtgtag ccagcttcta
    38461 aaaactcaga caaggcttca tctcctacac gacccttggt attgataact gccaaggtaa
    38521 acttagctag ggtatccaat ttaggatctg tttcaattgg agtacgattg cgaagagctt
    38581 gaatcaagtc atcattcatc tggatttgtt tgatggaaaa ggctgtgtga cctgcgacac
    38641 agaaggcaca accattggtc acggctgccg tgatttgcac cacttcacgc tcaacgggtg
    38701 tcaggctgtt gcgacggtgg atagatgaga caatttggta ggcttctaaa acagtcgggg
    38761 cattggccaa gagaccgatt aggttgggaa tatagccatt gttgtctttt tctactgttt
    38821 caagaatttc tttcacttct gctggtgctg actctactgt atggatagta aatgttgtca
    38881 taagatacct cttttcttat tattgacact aatattattg gaaaatctta taaaatcctg
    38941 attcctaagt ttatctaaga taaagcttta ttctctcata agattttcgt tgttatatta
    39001 gtttatcaca cttccaatca cttgcataat atatattata tatcaggctg ataaaaatta
    39061 tttataggca aaaaaatcac acgagctgtg tgattccatt atttgtcaaa atacttttta
    39121 gtttcagcaa taacgactgg cgacaagacc aagagggcaa tcaagtttgg cagagccatc
    39181 aaggcgttaa cgatatctgc gataatccag accatatcca actcgataaa tcctcctaac
    39241 aagaccatga gcacaaaaaa cacacggtag agccagataa agcgagcccc aaagaggaac
    39301 tcaaaacagc gttctccgta atagttccaa cctagaatcg ttgtaaaggc aaaaagtaca
    39361 aggaagatgg tcaagagggc aggcccaaag tgtgaaaaga ctgttgagaa agctgactga
    39421 gtcaaggcaa ccccattcaa gtcaccactc caaactccag ttaccaagat ggtcaaacca
    39481 gttagagtac aaatgatgag ggtatcaata aaggttcctg tcatggaaat caaaccttgc
    39541 tctactggtt catttgtctt ggcagctgca gctgcaatag gagcagaacc cagaccagat
    39601 tcgtttgaga acacaccacg cgccacacca ttttgaatag ccatccgaac gctagcacca
    39661 gcaaatccac ctaccgcagc aaggggacta aaagctgagg taaagactaa agcgattgtg
    39721 ccagggattt ttccgatatt aaagaaaata actgtaagag ttcctaagat ataaatgagg
    39781 gccataaaag gaacaacagt agttgaaacc ttagaaatag acttgagtcc accaaagact
    39841 gcaatcgcta caaagacaga caagacgaga gctgtgatgg ctggcgaaat cgtcgttgta
    39901 ttttggatag attctgtaat cgagttgact tgggtgaagg ttccgattcc caagagagca
    39961 accaatactc ctgctactgc aaacaaaaca gcaagtggtc gccacttttc tcccatccct
    40021 agaaggatat agtgcatggg acctcccgct actgcaccat ggtcgtcctt ggtgcggtat
    40081 ttgatggcca agagtccttc cgcatacttg gtagccattc caaagaaagc cgccatccac
    40141 atccaaaata gagctcctgg tccaccaacc ttgatagccg tcgcaactcc tatgatattt
    40201 cctgttccaa cagttgatgc caaggctgta cacagagctg caaaactgga tacatcacca
    40261 tgtcccttat cctggataaa aataagctga aaggccttgg gcagacgcaa aacctgcaag
    40321 agtcctagcc gcatggttag gtaaatccct gttccgacca ataaaatcaa gaggggcggt
    40381 ccccaagcaa aagcatcgat tgatttaagc aattctaaca tttccttctc ctatcgtttc
    40441 aaccccaaaa gaaagagcac atgcaagata catgtactct ggaatgctta gataaatgct
    40501 aaaaagcggt ctatcctagc tctgtccttt tacctgagag tttgagcagt tgcctgcctt
    40561 gccccttcgg tgcctttacg gtctctccag agttccgtcc atttacagtc atggaaaatc
    40621 aaacgattcc ccacttctat taaacttcat tcggtgttgg tatttaattg attctaattt
    40681 tacaaaaaat gttggctttt gtcaatgtgt ttattagtaa aaattagttc aacagttttt
    40741 actttataaa gtccagaata ctgctatcct ttaaaagtga caatagtcgc accactgcct
    40801 ccagcatttt gtggggcata gccgaaactc ttgacatgtt tgtttctttg caagtatttg
    40861 gtaactcctt cacggatgac tcctgttccg ataccatgga tgatatcaac ttgagccata
    40921 ttgttaagca aggcttggtc gatgaaggta tctagctcat tcatggcttc ttcatagcgc
    40981 ttgcctcgaa gatccagtct agcttgaggt cctcgcccag aagttcgttt cacaacattg
    41041 acctgtttct tcttgactgg tttttcttgc tgggcttgaa caagatcaaa ctctttctct
    41101 tccaaggtca tcttaatcaa gccaacttgg gcttcccagc gaccgtcctt gagttgactg
    41161 gtcaaggtac cacgctgacc ataactgaga accacgatat catctcccac ctttggagct
    41221 cgttttttct tggccttttg aaggacctta tttttagaca agtccacttt ttcaggagcc
    41281 aattttttca acttggcctt ggcttcaatg atttcgtggg gcttgagttg ggatttactg
    41341 tggagatttt tgagaatctg gtcactttca cttagggcca tatccacaat ctcagcagcc
    41401 tgttcacgcg ccttgttaag ctcggtttcc ttttcacgat taagctcgtt gtagagtttt
    41461 tttagcgcac ggttcatctt gagattttct tgctccacct cacggatatt gtccaaacgt
    41521 ttgcggcttt ccagcgtctg ctcttctaat tgctcaatga tacgattgac gtcattgtcc
    41581 tgatcgatct gctgactggc atctcctacg ataacttcag ataggcctag acgtttggca
    41641 atttcaaagg cattacttcg gccaggaaca ccctgcataa agcgataggt cgggcgaaga
    41701 gttgcagtat caaactccat actggcattt tgcacaaagg ctgtctcaat accgtaggcc
    41761 ttgagttctg gatagtgggt cgtcgccatg gtcttgattt gacgcaggcg aaggtcctcc
    41821 agaatagcca tggcaagggc tgctccctct tggggatcag taccagcccc caactcatcc
    41881 aaaagtaaga gtgaatgttg gttgaccttg ccaagaatat ccacgatatt ggtcatatgg
    41941 ctagagaagg tagacaagct ctgctcaata gactgctcat ctccaatatc agcaaagatt
    42001 tcttcaaaaa taccaacacg acttcccttg tctgctaaaa tcggcaatcc tgactgggcc
    42061 atgacctgtg tcaagcccag agttttgagc atgatggtct tcccacctgt attgggacct
    42121 gtaatgacaa tagctgttaa atcttgacca aaatggacat catttgcgac ggcatttttg
    42181 accaaaggat ggcagacatg gagcagttga atctcttgat tttctgacag ctgaggcacg
    42241 actgcttgtc tttcttggat aaatcgaacc ttggcacgaa tcaagtccag atgaccgata
    42301 atccaagcgt cattagcaat ctcagccgca tgagggcgga cacgctcaga aatttcttgg
    42361 agaatgcgaa gcatttcata gcgctcatct gctcgcagac tagcaatttc ttcgctcagt
    42421 ttgactacct cacgtggttc gatatagacg gtgtttccac tagcagaaat atcatgaacg
    42481 acacctgcaa tcttattgcg gtaggtgttt ttgactggta aaacctgacg gccatttctg
    42541 ctagcaacaa ttccttccgt caacatctgc gctttttgct tgagcaagtc ttgtaaaaca
    42601 tcgcgtacct gactctcgct atcatgtatt tttcgacgga ttcgcgccaa ttcttcactg
    42661 gcaaaatttt caatgaaacc cgcatcatta aaggcctgaa gatttccttg taattgcgga
    42721 aaatcatgta atttctcaaa ccaaagggct aattcttcca agctgacatt ttccagattg
    42781 gcataaaaac tttgaagttc tcggctggca agaagcacgc gtttcaagag taggaactcc
    42841 tcgatattga gatccgctcc catctccaac ctcttgcaga ctcctgcaat ttccttagtt
    42901 gagagaatag taaaatgcgg ttgctcgacg aaaagagcct gcatttcttt catctcagca
    42961 aaagcctgtt tgattttatc tgctttggca gtcggagcca gctgtctcaa ttgctccaag
    43021 ccctgctcgg tcaacaaatg aggatcaaac aaggccttga ccttatcgaa ctctaatgtt
    43081 tctaatattt tcttattcat ctttatttcc ttgtctttga atgtctaggt gtggtagctt
    43141 tttacattct gatagattcg agtcaaatct gtaaacaaag ggctaggaaa actcctgccc
    43201 tttttatccg attaaatttg tcacccagat ttgtttgagc caactggttg ttatcggtat
    43261 gctctggatg atgtgttttg cgacgatact cttttcaaga ggattttgta taactgccat
    43321 ggggatggtc gccaagattg tcaaggccat ttgcaagaca aataaggtca ccaacatgga
    43381 caagatacct gctgaaactt ggaacaactt accacccagt tttttgctag gaatcaagtg
    43441 taagagaaga ccaagcaaac gaccaatgct atagaaaatc ccaaatacaa gcaagtagcc
    43501 gatacctgca taaaagacct tatccagctg aaagagttga tccgatggga aaaagaaagt
    43561 cccctgacct tcctgcgaat ttgcataagg gagcaataaa tggaattgct ctccaagccc
    43621 cttataaaac tggccagcca taaaagccga tgccatggct gaaatcaggt aataaacctg
    43681 taagagcagg cctctccgat agccgatata aaatccccaa accaagacca atagaagaag
    43741 gaatgaaatc ataaggaatc ctcaatcttg ctctgttctt gcttacaagt cacaagcttg
    43801 tgacggagtt cttctagctc ttgctcctta tcgtcaaatt caatctcacg gctgagctga
    43861 gttgataaac agttgactgc caacaaaaga gcgattgttt catcatctgc gctaggcatt
    43921 tgttctttaa ttgcttggta tttttctgtc gcaaccttag cgatttcctc cataaaaagg
    43981 ttatcatgtt cgcttgtcaa ggttaacgat tttttcccga atgtaaattt gaatcgattt
    44041 agatttgcca taaaattcac ctcacgatat tataccaaaa ttcgctaatt ttgtcagttt
    44101 ttacaaattt tactgctttt gtggtacaat agaaactatg gcaagtatca cactcacacc
    44161 aagcgaaaag gatattcagg cttttcttga acactatcaa accagtctgg ctcccagtaa
    44221 gaatccctat atccgctact ttttgaaact acctcaagca acggtttcta tctatacttc
    44281 tggaaaaatc ttgcttcagg gtgaaggggc tgagaaatac gctagtttct ttggctatca
    44341 acttgtagag gaaaacaggg ggcaaaatct tcctttaatt gggacagatg aggtgggaaa
    44401 tggttcctac tttggtgggc ttgcagttgt ggctgccttt gtcacatctg accagcacga
    44461 ctttttacga aaactcggtg tgggggattc taagactctg accgaccaaa agatccgtca
    44521 gattgctcct attctcaagg aaaaaatcca gcaccaggca ctccttctct cacccagcaa
    44581 gtacaacgag gtcatcggag accgctacaa tgctgtttcg gttaaggttg ccctccataa
    44641 tcaggctatc tatctcctcc ttcaaaaagg tgttcagcct gagaaaattg tgattgatgc
    44701 ctttaccagt gctaaaaatt atgacaagta cttggcacaa gaggccaatc gtttcagcaa
    44761 tcctatcagc ttagaagaaa aggctgaggg caaatacttg tctgtcgcag tttcttctgt
    44821 cattgcgcgt gatctctttc tggaaaatct tgaaaatttg ggacgagaac tgggttatca
    44881 gctcccaagt ggagctggaa cggcttctga caaggtggct agccagattt tgcaagccta
    44941 tggtatgcag ggactcagct tctgcgccaa attgcacttt aaaaacactg aaaaagcgaa
    45001 aaaacgctta gaaaggtaag ttatgaattc atttaaaaat ttcttaaaag agtggggatt
    45061 gttcctccta attctgtcat tactagcttt aagtcgtatc tttttttgga gcaatgttcg
    45121 cgtagaagga cattccatgg atccgaccct agcggatggc gaaattctct tcgttgtaaa
    45181 acaccttcct attgaccgtt ttgatatcgt ggtggcccat gaggaagatg gcaataagga
    45241 catcgtcaag cgcgtgattg gaatgcctgg cgacaccatt cgttacgaaa atgataaact
    45301 ctacatcaat gacaaagaaa cggacgagcc ttatctagca gactatatca aacgcttcaa
    45361 ggatgacaaa ctccaaagca cctactcagg caagggcttt gaaggaaata aaggaacttt
    45421 ctttagaagt atcgctcaaa aagcccaagc cttcacagtt gatgtcaact acaacaccaa
    45481 ctttagcttt actgttccag aaggagaata ccttctcctc ggagatgacc gcttggtttc
    45541 gagcgacagc cgccacgtag gtaccttcaa agcaaaagat atcacagggg aagctaaatt
    45601 ccgcttctgg ccaatcaccc gtatcggaac attttaagag acctaagagg ccgagaatca
    45661 ccaatctcag cctcttcttc tatcgtgaga agtgattgtt tattgacaaa tactcaacga
    45721 aaatcaaaga acaaactagg aagctagccg taggctgctt aaaacagtgt tttgaggttg
    45781 tggatagaac tgacgaagtc agctcaaaat actgttttga ggttgcagat ggaagctgac
    45841 gtggtttgaa gatattttcg aagagtataa aataaaaaca atcccaactc tcacctattc
    45901 atgcaaagga attttatgga agtttatttt tcaggaacca ttgaacggat tatttttgaa
    45961 aatcccagca atttttatcg catcctcctc ctagaaatcg acgatacgga cgcagaggat
    46021 tttgatgatt ttgaaatcat tgtcacagga accatggctg atgtaattga gggcgaagac
    46081 tatacttttt gggggcaaat tgtccagcac tccaagtatg gagaacaact gcaaatcagt
    46141 cgttatgatc gcgcaaaacc aactagtaag ggcttggtca agtacttttc aagtagccat
    46201 ttcaagggga ttggtctcaa gacagctcag aaaatcgtgg atacctatgg cgaaaatacc
    46261 attgacgaaa ttttgcaaca cccagaaaag ttagaaggca tcgcaggact ctctgccaaa
    46321 aatcgcgagg ctttcgtctc cactctccgt ctcaactacg gaacggagat ggttttgtcc
    46381 aaactagcca actacggcat tcccaacaaa ctagcctttc agattcaaga cttttacaag
    46441 gaagaaaccc ttgatgtggt tgaaaattat ccctaccagc tggttgagga tatcaagggt
    46501 ttgggcttta ccattgctga ccaactagct gaggaactag gcatcgaaag tcaggctcct
    46561 gaacgcttcc gcgccggtct agttcacagt ctttttcagg cctgtatgga aacaggggac
    46621 acctatgttg aagcacggga tttgctggaa caaaccctta ctctccttga gtcttcccgt
    46681 cccgtggaac tagaccccag ccaagttgcc caagagctct cctacctgat cgaagaagac
    46741 aaggttcagc agattgatac caagatcttt gacaacagcc tctttttcgc tgaggaaggc
    46801 atccgcagtc acttggttcg tatccttgaa aaaggaaaac agaagagtca tgatttagaa
    46861 accattcaaa aacatatcac tactatcgag gaagagctgg gaattgagta tgataacatt
    46921 caaaaacagg ctatctgtga tgctatccag aataaggtct ttatcctgac aggtgggcct
    46981 ggtactggta agacaactgt tatcaatgga atcatcgctg tttatgccct gttagaggga
    47041 cttgacttca ggaagaaaag caatctgcct attcttcttg ctgctccaac tggtcgagct
    47101 gctcgtcgca tgaatgaatt gacaggtttg cctagcgcga ccatacatcg ccacttggga
    47161 atgacaggtg acgatgatac cagtcatctg gaagattacc tagatgctga ctttatcatc
    47221 gtggatgaat tctctatggt agatacttgg ctggccaatc aactcttctc caatatctct
    47281 tctaacagta agatcctcat cgtaggtgac agtgatcagc taccttctgt cagtcctgga
    47341 caggttctag cggatctgct tcatattcct ttgattcctc agactcactt ggaaaaaatt
    47401 tatcgacaaa gcaaagaatc aaccatcgtc accctagcta gtcagattcg acagggcatc
    47461 ttgccagctg atttcaccca aaaaaaagct gaccgttcct actttgaaat tgctagtggc
    47521 catattcctg ccaccattga aaaaatctta ggtgccgccc tcagaaatgg tattcctgcc
    47581 cgtgatatcc aagttctggc tcctatgtac cgagggacgg cagggattga tgctatcaat
    47641 cagctcatgc aagacctgct caatccccca caaaaagatc aactcagttt tgaagctcct
    47701 cagtgccact atcgtaaggg agacaaggtc attcatttgg ttaacgatgc tgaaatcaat
    47761 gtctttaatg gggatttagg agctatcaca gacctgattc ctggtaaata caccgaatcg
    47821 aaacaagacg agattgtcat tgattttgat ggtaatgaag tctcttaccc ccgtaacgaa
    47881 tggtacaaga ttcgcttggc ctatgccatg agtattcata agtctcaggg aagtgagttc
    47941 ccagttgtca tcctaccgat tactagtgct agccgacgta tgctggagcg aaatctcatc
    48001 tacacagcca ttacacgtgc caaaagcaaa ctcatcttac taggcgaatt acaagccttc
    48061 gactatgcta cccaacacat cggaactgcc cgaaaaacct atctgattga acgcttcagt
    48121 gatctactgg agaatgttga agaaaagcaa caagctgtct ctgaaacagt cacatcaagt
    48181 gcctctgaac aatcctacat cctaaccgaa gaaaactggg acagcattcc agccatgatt
    48241 gggattacag acacagacct caaagagatt tttggaaaat agtgcatcag aaaaaccacc
    48301 aattcaggtg ggttttctgt ttattaagat tattttactg ttgctgtgct tgtaatcaat
    48361 tcaacagctt ttttgatagt gatatcatgt ttcaacatgt cagctgaaag caagttttga
    48421 acttgtgcaa cttccatgtt gtagtctgct gccaattgct caacttcttt ttggatttct
    48481 tcttctgaag catcaaatcc ttcagctttg gcaactgctt cgataacaag gttagtctta
    48541 gtacgtgact cagcttctgc ttggtattgg ttgtgaaggt cttcttgagt agttccagta
    48601 atttggaagt acatgtcagg gttgatccct tgacgttgca agttcccaag gaattcattt
    48661 actgaacggt gaacttcttc gtggatcatt tcttctggaa gttctacgat ttcagcattt
    48721 tctacagctg tatcaattgc tgcaccttca actgcatctt tgtaagcttc ttctttagca
    48781 gcagccaatt ctttgcggta tttttctttc aagtcagcaa gtgtttcaac ttcttcatca
    48841 atgtcttttg caagttcatc gtcaagagct ggaacttctt tagcttttac ttcgtggata
    48901 gttgtcacga atttagcttc tttacctgca aggtcttctg cttggtagtc ttctgggaat
    48961 gttacgataa catcaacggt ttcgccagct gagtgaccta ccaattggtc ttcgaaacca
    49021 gggatgaatt gacctgaacc aagtccaagt gagaagtttt caccttttcc accgtcaaat
    49081 tcaacaccgt cgatagaacc aacgaagtcg atcacaacag tgtcgccgtc ttcagcagca
    49141 gcttccttga taaccaattc agccaggttg ttgcgttcac gttcgatacg ctcttcgaca
    49201 tcagcgtcag ttacttcttt ttctacatca actgatactt caaggttttt gtagtcaccc
    49261 aattttactt caggttttgt aacaacttca gcagcgataa cccagtcttg acctttttcc
    49321 attgaagtta cgtcaatttt tggttgggca accacttcaa gaccagcctc ttttacagct
    49381 gcttcataag cgtttggcaa aagagcgttc ataacgtctt ggtaaagtga ttcttcacca
    49441 aattttttat cgaagatagg acgtggaagg tgacctttac ggaaacctgg aacattaaga
    49501 gatttcttca ctgacttgaa gacacggtcc aattctggtt tgatttggtc ttgagagata
    49561 gtgaaagtca agacaccacg gtttgtttct ttgttttcaa atgatacaga cattctgtca
    49621 tttctcctta aaatttttta aatacagtct attataacat tttctataaa taaaatctag
    49681 actaatgcag acaattatag acaacaagcc tttttcctaa ctaaaacact cataaagtat
    49741 agacaatttt agactacttt ggatatcttt tggttagtca ttttccaaaa ctaatttatc
    49801 taatttttaa gttatatttg acttcatctt ctcagtaaca tgagtataaa cacttaaaat
    49861 ctttgtttca ttagtataat ctacacgatc cattatcgct gttataggta cttccaattc
    49921 agcaagcaaa cttatatgcg aatatctaaa aacatgagca gtcaatacaa aatcatcttt
    49981 cttaatttca cttttcctaa acctgttttt caaaaagtaa ttgaaacaag ttatcattaa
    50041 gggagaacca ttatttgtaa atatataatc accttcttct aaaagaagat attcttttaa
    50101 aatttctaac actctatcac taataccaat tactctatat gaagctaaac ttttcggact
    50161 atccaaaaac acttcgttat tggacgatta cattatagta aaacgaaata agaacaggac
    50221 aaatcgatca ggacagtcaa atcaatttct aacaatgttt tagaagtaga ggtgtactat
    50281 tatagtttca atctactata caagacgaaa ttgaagaaat ctttccatta taaaacgcat
    50341 attatcaagg tttttaaaca cctaataata tgcgtttttt cctattttaa agacttttat
    50401 ccacctatta tacaaagtta agtatccatc acagtttaca attagccttc attacctaac
    50461 ccattcacca tccttcaaga gagtaacctt taagaaccga ataaataaat ggcaaatttc
    50521 gttcatttaa tttaactgca ctgttaattt gattagctcc atctcctaaa gtatgcactc
    50581 ctactacacg gtgactagca tcataaactg tagatccact agacccctct aaagtatcaa
    50641 cttggtaatc caagaacatg ccatcatcac ttaaaacttg ttttttatct gtatacattt
    50701 gatgaacttt aaaattatat gatggatagc ctgtgatagt cacagttatt cctgtcaaat
    50761 ttttttgact agtaggaaga cccaaagtcc ctaattttgc accaatgggc tcttctagaa
    50821 ttaataaagc caagtcatat tcccttgcat ccttagaatt taaatttcta aattccttca
    50881 aataacgaac ttcctttact ttgatctttc caaatggttc ttgacttgga ctaacagtcg
    50941 gaagaacata aatatcatcc gcttctttcc catagtcatg tctgtagtag ttgtgagccg
    51001 ctgtaattaa cacattatct ttaataaaat tcgcacttcc cctcccttct acattcattc
    51061 catcggctac tccataatac ttagataaaa ccatagctga agtcgaatac ggatactgta
    51121 aagtattatc aattttaatc aaatcatcat taccgataat acttctgatt gcttttggta
    51181 gtatgaacca tatgttggtg aaatctcaga taatgaagaa tcattagatc ctggaccttt
    51241 ttctagtgtc tcacttacct catattcttc acccgtacta gaaataacac tcaaagcaga
    51301 tactgtcgat aactggctag ccaataaagt actcgcaata attgaaatac ccaatttttt
    51361 ataaacagtt ttcttcatta ttgtatcctc ctaatgtaat tatagcgtac tattctaaat
    51421 ttcttaatct actatagaat caagaaatct accaccttct ttaaataccc tccattatca
    51481 cataaacagg taaacttttc aattaatgac tgcgcttttc aatcacgcta gaggtactta
    51541 cttgcttctt tgatactaag ttcagccatt ctttccttgt ttttctcaat aaagcatgtt
    51601 acccaagtgg gattcgtttt ggagtagtct cgcagagtcc agccaatggc tttattgata
    51661 aaaaattctg tttggttcaa gttatgaagt agaatctttt ccattaattg agtattggtc
    51721 ttctcttttc ttaacaactg gtggtcaata gcgacacgtc tcagccagat attatctgat
    51781 aggctccatt ttatactcaa tgaaaatcaa agagcaaact aggaagctat ctgcaacctc
    51841 aaaacactgt tttgaggttg cagatagagc tgacgtggtt tgaagagatt ttcgaagagt
    51901 attaagatta tttcttctag ttcagggtgt tcatacacca aactccctac tactcgatct
    51961 aggatatcta ccgtgtccca ccaggatttt gtcacgacta actgctctag cttaggcaaa
    52021 tcggtttcct ttagataaga ctgcattgct ttcaaatagt tagcagccac atattggtat
    52081 tttctaggct ccttttccca gcaagtgtct gcaaaatccc aatcgataat ctttgttttt
    52141 ttcgcttctg gtaaatattt ttatagagtt tatttctttc aggcaccgca atacctagaa
    52201 aagaaaattg atggcgcata taggcttcca tgggccttgc ttttttagag tcttttgctg
    52261 cttctagctc ctcaagtaaa tctgctaaac tcatctaaaa ctcctcttgc cccaccaaat
    52321 ggtgctgaaa ggcatagaca gccgcctggg tacgatcgct gacttcaagt ttggcaagaa
    52381 tattggacac gtgggtcttg accgtcttga gagagataaa gaggtcatct gcgatgcgct
    52441 gattttcgta gcccttggcg atgagttgga gaacatctcg ctcacgcgca gtcaattctt
    52501 catgaagttc catatgattg cggtggtatt caaccttctt gctaacctct tgctcaatgg
    52561 ccagctcgcc agcagctacc ttactgacgg catgaagcaa ttcatctgca ctagaagtct
    52621 tgagcatata gcctttggca ccagcatcta agactggcat gattttttca ttgtccaaat
    52681 aagaggtcac aatcaaaatc ttggcttcag gccattcttt aaggattgct aaggtcgcgt
    52741 caatcccatt catctcaggc atgacaatat ccatgacaat gacatctgga cgcagttcca
    52801 aggccaagtc aatcccttga gacccgttgg acgcctcacc cacaacttct acatcgtctt
    52861 ggaggtcaaa gtagcttttc aagcccaaac ggaccatttc atggtcatct actagtaaaa
    52921 ttttcatctt tactccttta tcattcctta tctaacaggg gaatacggat atcaactgcc
    52981 agcccttgct tgggagctgt taataactga accgtccctg ccatatcttc aacccgctcc
    53041 ttgatatttc gcagtccata actcaagtcg tctaagcttc ctaaccggaa accaatccca
    53101 ttgtccacca ccttcagttg caattcaaca tctgtctgat agaggtagac atctaggcaa
    53161 gatgcctggg catggcggag ggtattgcta atcaactctt gcaggatacg gaagatatgc
    53221 tcctcgattt tcttaggcaa tttcgtcata ttctgcttga gactaaccct aagatcactc
    53281 ttgtcctcaa gctcttttaa gagaatctga atcccttcta tcaagctctt ctgctccagt
    53341 tcaactggtc gcaaatgcaa gagcaaaacc cgcaaatcct tctgggcagt ttctaaaata
    53401 gctgtgacac tctgcaactg ggtctgcatc ttttctctat ccaatttcaa agcctgctga
    53461 ctgatacccg ataaaataat gtgggccgca aacaactcct gactgactgt atcgtgcaaa
    53521 tcccgagcaa ttcgcttccg ttccttctcg ataatttcct cttcctgatc aaggctatga
    53581 ttttcagctt tttgaagagc ctctgtcaaa aggttaagtt tacctgataa ggacttgaaa
    53641 ctggcatcca aatctggatc tacaacctga actacttctt gccctgccaa taaacgcttg
    53701 agattagcct gcatttttct tagagaaagc tcttcgatcc ctcgccaaaa cagggctaag
    53761 agacaggtca tggacatgct gaaaaccaac aataaaaaga caaatttttc tgttttttcg
    53821 acatcgtaca aaaagataga ccagtcaaaa tcaagtattt ccagcaagct gtgggagaaa
    53881 aaaaagacaa ataggaagga ggtgagagca ataatgacat aggcttgttt tttcatcctc
    53941 taaccacctc cacatcacca atcatagtgg tcaagaaaat cttgacactc ttgttactct
    54001 tgagatagtc ttttgtttct tgatgatagt gttcattgcg gagggctcgc ttgggctggt
    54061 tgaaaaaagt caaatcccca tagagacagt taacgctgag actgacttcc acatctacag
    54121 gtacgatgat tttggtcgtt cctaccatct ttctgaggat aatgacattg tcatgattgg
    54181 ttaagatgac tctctccaga tgaatagtgt ccttgcccat gaagcgaaag agattgatat
    54241 catcaaattg gcaagtctgg tagcttgaaa aatgatgaag atttccaaac caacgatttt
    54301 tctccttctt aaccgtcaca acctcttcaa aaaccaaatt ggtctgctct ttttcctggt
    54361 tcatcatcgg gtaaagaaga aagagactat agataaccgc aacaaaaata gctagaatca
    54421 caaaaggatt gagcataacg atgaaaaaga agagaatggt tgccgctact aaaagaagat
    54481 tattcccctc tttaccagta tagtagcgaa tcaaaagcaa aaagaggaat agtatcagca
    54541 gaaaacgcga aaaatgctct gataccatca aaatcagagc tcctgtcaga agacaggctt
    54601 cgataaataa aaagatttta aattttctca taggttcatc ctctcccttc tattttatca
    54661 caattcaaaa aagtcacctc agtctgagga tggaaaaaaa ggcgctggtt acgccttttt
    54721 catctgatcc tttgcttctt ttaattttcc ataaagaaga tagtctactt tttgtagatc
    54781 tgctatggtg gcacagttaa gggaacacat aatcaagcgt agatctgctt tccagccttg
    54841 gacaatgcca atcacttctt caactgtgta ggtttcaacc aattccagaa cggttcgtga
    54901 caatcccaca gccttagcac caaaaaccaa gcacttaatc atatccagcg gattccgaac
    54961 ccctccacta accaagagtt cgaccttatc tttccattct tgggcattga gaagggcctg
    55021 catggtagac tgaccccatt gattgaggta atcacgctgg ccactacgac ggttttcgat
    55081 ataggcaaag ctggtgccac cacgacccga taggtccact gtacgaacac cgaattcata
    55141 ggctctttcg attgtcttgg catccattcc aaagcccact tccttgagga caataggaac
    55201 gggaatttgc ttgctataat ctgctagatg cgattgccag cttctaaact tcctttctcc
    55261 ctcgggcatg agtaattcct gcatgacatt gacatgcact tgcaatagaa caggattcat
    55321 ctcttctaca gtctgaagtc ctaactcgac aggtttgtcc aatccaatat tggttccaag
    55381 gaggagattg ggatgactag acttgacaga aaaagaatca tccgttggat ttttgagggc
    55441 tgcgctataa gaacccgtta caaataaaat accacaggat tccgccacct gagccagctt
    55501 ttgattgatt tctcttccct tattacttcc accagtcatg gcattgatat aaaaaggaaa
    55561 gtcccacttt cgaccagcaa actctgtcga aagatcgatt tcatccagat tgtaaagagg
    55621 caaggaagaa tgaatcagct ccacctcatc aaagctatta taggaacttt tctgctcaag
    55681 ggcatagagg atatgctcgt ccttacgatt tgtcgtcatg tcctatcctt tcttgatata
    55741 agagctcaat ccccagatcg gcccaacgat tttttaaggt tttggttgat tgcgcatcaa
    55801 aactcagggc gatgccacag tcaccaccac cagcaccact actcttggca acggcctgca
    55861 aatcttgact ggcttctttc aactgtctaa gcaaaggcgt gtaaatatct gtactcaagc
    55921 cttctaaaag cttgctggct acttctactt gctcgataat cttttctgat ttcccctgtt
    55981 ccaaggcttc gaccaaagaa accaccgttt cttttgagga acttaaaaaa ttttgattga
    56041 tattttgctt gatttgctgg accatgtgac tcgatacagc cacttccttg gtccatccca
    56101 ctaagaaatc acattctaaa gttggtttca cttgtgaaat tgaaaagccc caatcacgct
    56161 ccagaactgt cgccaagttt tcttcttcta accaagcagc caccttctgg cgatcaaatg
    56221 actggtagag aaccaaatcc tctgccacaa tacaggcaag gtcgcccatg gaaccattgt
    56281 ctcctcgctt gagcaagaca gcgctagtca gcttgaacaa gagctcctga tcaacagaaa
    56341 catcatacag agccagtaaa gccttgacaa ccaagacaac gacgctgcca ctagaaccta
    56401 gaccaaactt tttcccttct cgttccattt tgccacagat ttctagggaa aaagatctta
    56461 aattctgacc gcgaacagcg aggaagtctc ccatcaaagc aatcgtttct tgaatcaagc
    56521 tgtagtcagg attgggcgtt aagtccactg cgaaatcaaa catatctgaa tagatacggt
    56581 agctgtcaga aaaagcaatc tcagccctca tatagatggg aatatccttt atcaaagcta
    56641 actgccctgg ctctaaaata gcatattcac ctgcccaata gagttttccg caagttttaa
    56701 cagcaatcat cttgactcaa atcctttgtt tttgacacaa tcaagcgata acgctgaccg
    56761 aaaatttctg acaaatgctc caagtctttc tcctgacaaa agaccttaac attgggacca
    56821 gcatccatgg taaagtagca ggcctctcct ttctcacgaa gctggcgaac aaagtccata
    56881 gcctcataag aggcatccgt cagataagaa aaggctggac tagcagtctt tgtcgtagca
    56941 tgcatagcca gggcattttt ctccgttaat tctccaatct tggcaaaatc attttccttg
    57001 agataaatca gcatatcctg atagtccttc tcagactgac gaacccagtc gtcaaaagtc
    57061 gtcgaggttt ccacacaaag tttcatcccg tcacggctag agattggttt tttcttgtcc
    57121 tctagcacca acataatcat agctagtttc aagtctgtct ctacagagta aatttctcca
    57181 ctatccttat cccaggctcc tagcggtcca taaaaactcc gagaagaaga gcctgaggca
    57241 aacttggctt cctgcgctaa ctgacttcta tccaatccaa gcttgaaata agcattacaa
    57301 gccttgacca gggcggacaa accactagaa cttgaggaca ggcccgctgc agtaggcata
    57361 ttgttttgag tatcgatacg gacaaagccc tcaccagctg gacgataacg gtcaataatc
    57421 ttactcatct tggcatgctc gacctcattt tgtagctgac cattgatgta aaattcgtca
    57481 gctattacat tggctggtaa aggcgacaag gtcgtctctg tatacatatt ttccaaagtt
    57541 agagaaatac tgctagtagc aggcaccatc tctttttctt ttttctttcc ccaatatttg
    57601 ataatagcaa tatttgcgta ggaacgtact gtcacaggct ctctatccat gtctgaacag
    57661 ctcctttctc ttctaatctt tctgctagtt cttgtgcgtg tgtcaaattg gttaccaagg
    57721 ctatgataca acctcctagc ccaccaccgc tcatcttggc acccagagca ccatggctaa
    57781 gagtcgtttc aaccaaaaag tctgcctcag ggctactgac tccaatttct tttaaatgta
    57841 aatgcgcttg actgaggatt tgtcccagtc cttcagcatc tttttgtgaa atcgcaactt
    57901 ctgcttgctg ggttaattct cccaaggcat gcaaaaacgg tagggcatcc ttgcccttat
    57961 tttgaaccac ttggatggct tcacgagtat gaccataaac acccgtatcg gcaatcacca
    58021 aataggcgga taaatccatc tcaagttctg taaatcctac gttcttgata aagcgaatag
    58081 gttggtcact gagacaggtc ttagcatcca aaccactagg attcatatgg gcaatcatct
    58141 cagctcgatt gaccaagatt tctagtacat catgaggcag atcagcctga tagtagtcaa
    58201 ataccgcacg aatggccgct atgctgatag ccgctgacga acccatcccc cgtttctcag
    58261 ggatagccga gtcaatctca caacgaatgc aggcttctgt gatatccaaa tactccagtg
    58321 aggcataaac cgccatggac aaggtatcct cctcataaag gcgccaagga ctctctgcag
    58381 gaactacctt acaggtcacc tccacctcca aaagaggcag ggaaatggca ggataaccgt
    58441 aaacgaccgc atgttcccct attaaaatta tcttactatg tgcctgaccg acaccaactt
    58501 tttttgtcat tttttccttt tactagacga aaaaacgtct tatttttcat acaagtatta
    58561 attctttcct atctatttta ttatattttc acaaaaaaag cgattgtttc cattcacaat
    58621 cgcttctttc attattgaac ccattcgcca ttatagttga cagaatagcc atctacggtc
    58681 gtattcactg ccaaggcacc tgagctataa gcgtagtacc atctgccatt gacctggaac
    58741 caacctgtcg tcatagaacg acgaaagaaa ctccataccg ttaagtaaag aggaaagtcg
    58801 tgagggatca tgcgccattg acaacctgtt ttagtgacgt acaaagtctc attaacaagt
    58861 actcgtttcg gccatttata ggtgcggtgt ttggagaaat agggttcaat cttagcccat
    58921 tcttgatcgt ttaaatcagt atcatatgct ttgcgtgtca taactctagt ttaacatttt
    58981 ttgtgaatac aagttctaaa taatcgacca cgaaaatttc ttaagtggaa aacgccttat
    59041 gaagtatgct acgggaaact tatgcactta atttgacaat tcaagatgta aaaatatata
    59101 ctatagtaga ttgaaactag aatagtacac ctctacttct aaaacatttt tagaaatcga
    59161 tttgactgtc ctgatcgatt tgtcctgtta ttattttatt ttactataat atttgacaag
    59221 ttatcctaaa agtattatta tgttgttgtg ttatagattg attgaatcta actaaaggat
    59281 cctattcaat tactagaact atcacatact caaggtcagc tcacagatga gcaactattt
    59341 tggttacaat gtctactaaa tttaagtcaa acaaataatt tagtcaaaat taaaaaaata
    59401 gaggaacata aatatgatta caaaacagaa tgtaatagtg ttctacgatt tttactagat
    59461 aaaactgtaa attctgaagg aaggatcact tcttcaacag aatttggaaa tttcgtaagt
    59521 aatttatcat tccaacacgg aatagctgga ctactgtttc ctctaaataa attgtacccc
    59581 ccagaactgg attctaaaat actctctatc atcaagaagg cagtgacaat tagaacgaca
    59641 cacatatgaa tatcaatact cactgctatt tggtgatgca ggctatctat ggttactcct
    59701 acatttattt tctatcagta aaaatcaata ctatctacaa ttagcaaacg tcaccgctaa
    59761 gaaattaata gagaattatg atactctaga agaaatagac tttgcattgg gaaaatctgg
    59821 tgtcctatta tcattaataa aatactatca atttaccaat gacaatactc ttaaaacttt
    59881 catccacaat agtatatggg gaaatttatc attatttcct acaaagagat acagccaaag
    59941 aaagcatttt agactatagc tttgctcatg gatattgtga aattgcatat gctttatttg
    60001 cctattctaa agtcttagaa ccttctatgt tctataatga tctccataca ttccatgctg
    60061 aattaaaaaa attattagaa aaagttactt ctaatactga aaatttagga aatttacaac
    60121 tttcttggtg cgaaggaatt tccggaataa tcttatatct ttgtatgtac gattgtgacg
    60181 gaaacaaaga tattattagt aaatatcaag aatttgtttt taaccatcat ctaaaaatga
    60241 tgacaggata ttgccacgga ataactagct tactacaaac cactgtctac aatcaaaaca
    60301 aattactgat gaaaaaaatc caacaggtaa ttttagcatg ttctgaacga gatgatcacg
    60361 gtttactgat gtttcaagga gatagtggta aagcagattt gtttgacttc ggaataggaa
    60421 gcagggggta tattggtgtc tattaaataa taaattccca ttcgatgtgc aaacataagg
    60481 agaaatgtat gaaattattt tggacaaaca acatatatag acagttgctg ctaaacagct
    60541 gtttttcatc attcggcgac agtattttct acctcgccat tatcaattat gtggctcagt
    60601 acaatttcgc tccgctagcg attttactga tttccatttc agagatggtt cccctactat
    60661 cgcaactctt tctcgggatt ctaggagatt ttcaagaaaa tagagtcaaa cacgcactct
    60721 gtattgccaa aatcaaaatc ctgctctacg ctattttgac agtatttctc gtcttgtcgc
    60781 ccttttcatt agtttcagtc attatgattg tcatcatcaa cctcatctct gacaccttga
    60841 gctacctgtc tgcctacatg atgaacgccc tctacatcag tgtaattaag gatgacctgc
    60901 atgatgccat ggggttcagg cagtctctga tgagggttgt ccacattgtc gccaatctgg
    60961 ctggcgcatt ccttatcaat gttataagta ttcaaactat ttcccttatc aacactctga
    61021 cttttgtcat tgcctttttg ggcctgtatg ttattcgaca taccttgtat gaggttgaaa
    61081 aaaggattga aatgtcacat acagcactga gttttaagaa atattttcaa catcttaaac
    61141 agtcgctggc tgtgctcctg aggttaaaag ataccgtcat actactgttt ctgacgacca
    61201 gtatgattgc catcttggat gtgtcccctc ggctgattgc cctccgcttc atccaacaga
    61261 cactagcaca actgagcatt gggcaactct tcgccctgct ctccatcatc atgtcttgtg
    61321 gagctatcct tggcaatatg accagcagta atctatttaa aaatatccgt ttcacgcacc
    61381 tcttggtttt ctgtgagatt tccctattgg ctctaataac tagtatcctt tgtcaagcct
    61441 atatcgtaat tttcgtgacc agtttcatca gttctacgat tatcggcatt ctcagccctc
    61501 gcctacaagc agctgtcttt gcccatatcc ccagtgacaa gatggggacg gtgggctctg
    61561 ctctgagcac agtagacatt ctcgccccgt ccctgctctc cctattagcc ctatccatag
    61621 catcgggcgt ttcggtgcag ttagcattga tatttttgta tcttattttg attgctctta
    61681 tcttttgtca atggttagtc aagttcaaca ctcataacta acgaaaaagc atgtgtagat
    61741 ttcacatgct tttaatctcc ccaatcgtca ggtcaagtac aacaaagtca cttctttgat
    61801 taagcgagtg ttctaatata attataagcg ccctgtcatt accgaaccca ttcgccatta
    61861 tagttgacag aatagccatc tacggtcgta ttcactgcca aagcacctga gctataagca
    61921 tagtaccagt tgccattgac ctggaaccaa cctgtcttca tgtctccatt acctgcattt
    61981 aggtagtacc aagttgaacc atcttgatac caaccagttg ccatagctcc tgatgaacgg
    62041 agatagtacc atttgttccc aaggttttgc caacctgttt tcatatcgcc atttggctgg
    62101 tctaaataat accaagtggt accttcctga taccagccag tggccattgc tcctgaggaa
    62161 cggaggtagt accatggagc aggtttgctt ctatcaatgt caatagtaac atgaaaatct
    62221 tgagtccaac ccttagcaac ttcaccaatt ggtagtggat tgtaagaatc atcaccaaaa
    62281 tttcctagct tatttaaata ataccaattg ccgtcttcat aaatccagcc tgtctttaca
    62341 gcataattat tatcaaaata ataagttctc ttttcagcag atagaggata ttgttcaccg
    62401 tatacttttc ctgtattttc agacgttttt gcctctagta cttgtttatc tgtttgttct
    62461 agcaaagcac catcttgtcc aaaatagtac cacttctcct gaaggccaat ttcgaagact
    62521 ggacgattat caaataaatc atcacgataa cctgttccag gaatttctaa gtattgccaa
    62581 ccgacaacca tctctccaat atcaccaaaa tagtaagttt taccgtctat tttatgccaa
    62641 tagattgctt tatgatcatc ttttacataa tattttctat tatccttatc aacaaatcgg
    62701 ccacctgtgg tattcgcaaa taccgtattt gtagctagca aaccaaagaa aaagactgct
    62761 agtagaactt gcatcatttt tttcaaaagt ttcatttata tatcctccta aaacgattgt
    62821 agcaaagaca cgactgcatg tcaatatata aaaactcctc aaaaaagcag ttacacaact
    62881 gcaactgctt ttctattctt gcatggtgta accaacacca cgcacggttt taatgtagct
    62941 tttttgtcct ttaacatcaa gcttgctccg tagatagcgg atatagacat ctacgatatt
    63001 tgtctcggtc gcactttcat acttccaaac actttccaac aattgctcac gagtcaatac
    63061 tttcttgctt cccataagtg tcgccaaaag gtcatactca cggcgggtca gagcaatcat
    63121 ctcttcacca cgataaaccg tgtgatgttc aacatctatc ctaagattgc ggtaggtcct
    63181 tggaactttc atcagactgc agtgttgatc aatgaagtcc cgacctcgga agatcgccga
    63241 aatacgcgct accagatttt cgataaagac tggcttatag atgtatgaaa ctgcaaaacg
    63301 ctgaacaact tccagctctt cttgcaagtc ttcccaatga tctaaaatca tgatgactga
    63361 ggcaggttta gttcgactca atttttctgc aaaatcctga gccatcatat ctcccagatt
    63421 aacgttcaat aaaatcaaat catagtctgt ctgaagagcc atggaaaggg ctttttgccc
    63481 ctcctctacc agatcaaccc gatactgctc tttctggagt tccaaactta aaaaatgagc
    63541 tagatttcgt tctttctcaa gtaataaaat ccgtttcccc atggctgacc tacttatttt
    63601 tcgtcatacc aagagtagtg gaaggttcct tctttgtctt tacgttggta agtgtgagca
    63661 ccaaagtagt cacgttgtgc ttggatcaag ttagccggaa ggtcagctga acggtagcta
    63721 tcaaagtaag taatagctgc tgagaaagtt ggcactggca caccagcttg aaccgcaaga
    63781 gctacgatat cacgcactgc ttgttgatac ttagcagtaa catccaagaa gtactcgtcc
    63841 aaaagaaggt tggcaagatc tgcatcgcgg ttgtaagcat ctgtaatctt ttgcaagaaa
    63901 cgagaacgga tgatacagcc atcacgccag atagatgcga tatctgcaaa tggcaagttc
    63961 cagttgtttt ctttagaggc tacacgcaat tgagcaaatc cttgtgcgta tgaaatgatt
    64021 tttgagaagt aaagggcttg acggattttt tcaatcaatt cagccttgtc tccttcaaag
    64081 ttgaaggcag ctggttttgg aagcaccttg ctagcatgta cacgttcttc tttgtaagtt
    64141 gaaatgtagc gtgcaaacac tgactcagta atcagtgaca atggtacacc aaggtcaaga
    64201 gatgattggc tcgtccattt accagttccc ttgttacctg cagcatcaag gatgtagtct
    64261 acgattggtc catcttggtc ttcatcgtct ttacggctca agatatcagc tgtgatttcg
    64321 atcaagtagc tatccaattc acccttgttc cactcagtaa agatttcagc catatcctct
    64381 gcagaaaggc ctagcaagtg ttgcatcaag tcatagcttt ctgcgatcaa ttgcatatca
    64441 ccgtactcga taccgttgtg aaccattttc acatagtgac cagctccatc aggaccgata
    64501 taagtcacac atggtttgcc atcttctggt gctttagctg agatttcttc aagaacatcc
    64561 gaaaccaatt cgtaggcctc tttttgtcca ccaggcatga tagaaggacc ttcaagggca
    64621 cctttttcac caccagaaac tccagtaccg ataaagttga tacctgagtt tgccaattct
    64681 tcattacgac ggatggtatc tttgtagaaa gtgtttcctc cgtcaatcaa gatatcacct
    64741 ttgtcaaggt gtggaagaag ggcttggata gtagcatctg taccaggtcc agcttgaacc
    64801 atcagcatga tacgacgagg tttttcgatt gagtttacaa aactttcaac gtcatagctt
    64861 ggtacaaaat tcttttcagg atggcaagca atcacatctt ccgttttttc tttactacgg
    64921 ttgtagatag caactgtgta accacgtgat tcaatattaa gggcaaggtt acgacccatt
    64981 acggccatac ctacgacacc aaagttagct tttgtcattt gacactcctc ttgtttcatt
    65041 tgttttattt tatcattttt acttttgaaa agaaagaatt ttgtaacgac tgcttagtag
    65101 tccaagtcat ccgcatgacc agcgccattt ccgacaaagt agcctgtctt acagttaagg
    65161 gtaaagagat aggttccatc tggcttatag aggttgtaat aaccattgcc gttaacgata
    65221 ttgacacgtt caaggatata ttggtctcca gtgatatagc cacgtgaacg tgaagttgct
    65281 agaatttgtt ccaaaacacc atccgcaaaa tcccaggcag agttattact atcatcaata
    65341 gcagactgat tataggcaac acgactggca cttctttgaa cagcaacccc tgcactcgag
    65401 agacccatat tgacttcact gcgactactt ctagtctcat ttgaactact tggttttggc
    65461 tcactagtcg tatttgaact tgcttgactt gaacttgagc tgctagtttg acttgaactt
    65521 gagctagaag tacttgtttg ctggctctta ccaagactga tagccttatc tagcacttta
    65581 tcaagctccg tatttccagt tttaatatcc gtaaatttag catccgattt ggctttggca
    65641 ttggtatcca acacaccatc cacaatagct ggtttttcaa attgtgcatt gacatcttga
    65701 atggccttga tttgcgttac tagactatca tatttagatt tggcaagcgt atgttcacga
    65761 ctaccttcca gcttatcaag taaagtcttg agttgactca gtttatcaaa ctggctattt
    65821 ttcaaagccg ttttattgct atttgtgtaa aaggcgtcat aaagtgtatt aaaatcatcc
    65881 acatccgatt gattggctgt agttgattga gaagtttcaa tttccttggt cgaacgagcc
    65941 acttgacgat agacataata agcactgaca caaataatta ctgatacaag cgccaaaacg
    66001 gtcaaaataa agcctttttt acttttcttt tctgagtcct cttgatccag acgagaaagg
    66061 ttttgctcct cttccacttc ttcagtcatt tctgttggat tttcatcatc tagcaataga
    66121 ggatccaagc cttgctcctc atcgtccaga ggcaagggta gtaagatgtc ttcagaagat
    66181 ggaacttcct ccgaagaagc ttctgacttc tctacagcct cacgcatctc ttgaattaaa
    66241 tcatccagac tctgagtttc aacgaactcc tcttttttgt attgacgagt cgcaaactta
    66301 tccgcctcaa tttcatctct gtgttgctta acatacttgt ccaaaatgga atcctcaggc
    66361 aagactcctg cttccacttc ttcattttta cgaatagctt gaccaactgt tagctctttt
    66421 gcttcatcaa aatcaaattg cggttcttga ccttcttttt tatgacgatt tcgtcttttt
    66481 ttactcatga gtatcccttt ctattttacc tcttgccgtt tgacacgctg accaaaatat
    66541 tgatatagat ccactttcaa ggttccgttg tataacttac gcttcttatc tgcttggcta
    66601 ccatacttgc tttcaaaagc ttcatcacta gtcaggataa atttgctcca agttttcagc
    66661 ggtgcaaata cttgccccat ctcagcatag agcttggtca ctcctgcatc atctgacaaa
    66721 cgttcaccat aaggcggatt ggaaatgatt actccattga ttttatcgga acgtaaatcc
    66781 tgcacgcgca tctgcttaaa agtaatatct cctgcaacac cagctgcctg agcattggcc
    66841 ttagcaattt ccaccatgcg agcatcaata tcacagccca tgatatccaa ctcaagctta
    66901 cgttctactt ttttagccgc ttctgtgcgc acttcttgaa tcaagcgatc gctgatccag
    66961 ttccattcct caaatgcaaa agagcgacga agacctggcg ccatctttct agcaatcata
    67021 actgcctcaa tacagaaagt ccccgaacca caggtcggat caatcaaagg cttgtctgga
    67081 taccagttag aaagttgtaa aatggctgct gccatatttt ccttgatagg agcgccacct
    67141 ttttcggtac gataaccacg tttaaagagg ctagacccgg tcgtatcaat catgacagtt
    67201 gccacatctt tgagaataga gacctcaatc ttaaactctg ggccattctc catcagagga
    67261 accccttctg ggcgagcata gtgtttctgc aatttcttga caacagcttt cttagaaata
    67321 gcctgaacac tgggctcatt gtgaagtttg gacttaacac atttagcttt tgaaatcggt
    67381 aaccgagctc caagtggtaa ataattttcc caatctaaag cgaaaactcc ctgaaatagc
    67441 tcttcaaaag tcttagctgg gaacgttcct acgataattt tgatacgatc tgctgcccga
    67501 agccaaaggt tggtttcgat aatagctctc acgtctcctt gaaaacgaac acgtccattt
    67561 tcaacctgac aatcgtagcc caactctcgc acttcacgac caacgacagc ctcaagccct
    67621 gctgccacag ttgcaattaa attaaattct tttttcatgt tacagtcttg caagaccttt
    67681 ctatatgtcc actttaaaaa atgaggttga gaaaatttct cagccccaac ctatatgcaa
    67741 ttttctataa gccatgtttt gttccagaag tgactaggac cacttccttc gataatcatc
    67801 tgtctaccac taacagctct agctgatagc agtcagaata ctacgttcgt ttccgcatac
    67861 tccatgcccc gaccaaaatt tgggttgcta gcttgagggg tttaccgcgt tccactctct
    67921 ctgtttccag aaagactccg tcactgtggc actttcaagc ctactctggc ctatccaagg
    67981 acttagccat ttcaactgcc gtaacgattt ctcgtcccta ggcttatggt ttcgcctagc
    68041 acaaacacta caggcatcac agcctgtgct agcatggact ttcctcatga gaagcaattc
    68101 tcctcacgcg attatccaaa aattgcacat ctcaaataac tacttaaaaa tctgagttat
    68161 ctaaaatttg tttaccaaaa acttcttttt ccaatctatt caggcgtttc aaaatatcaa
    68221 aattcgtcat agaacttgta attgccgctt caaggggttc tgcttgaact ggtgaaggtt
    68281 tcggtttacg agttaattct tccttcaaat ccgcaatttc ctgacgaagt gacttgacca
    68341 aggcagcata ggtttcatag tccttgatga catcgtctaa aaactcgtca acttctactt
    68401 tattatagcc acggacttca cgtccaaact cttgttcaaa aatatctttc gctgaaaaaa
    68461 taatacttgc catgtctctc tccattctcg cttgctagta ttattatata aaaaaaggca
    68521 aacaaaaatc aaggtcaaag cttcaatttt cggaaaaatt ttcagcaagt tcatttaatt
    68581 gatcaaatgt taatctcttt ataaaatagt cctcttgatt tttcatcttt tggtaaaaat
    68641 aagctagttt tgtttcattt tcttcatcat aaaaaagata ggaactagtc gtgttttcca
    68701 gcaaaaactg ctggtaatct cttaactgcc ccttgtgttc atagcgagga taagcatatt
    68761 tgacaaagtc tacctgctta aagcgactca gtttcatctg attgccttca ttccaatttt
    68821 ccccatgggt ttcaaaagca aaaatggtgg ccaactggaa accgtattcg gttttcatct
    68881 cctgagcaac ctctaaaacc caatattcaa aacccaaact ccctgtaaac acaagccaag
    68941 acaccccatc tgctgccata gcctctaaat ctttacgtat cgctttttta atcaatttaa
    69001 gacgaggatc cttatcagaa aataaaccca aatcaaaagc agaatagcct aaaaccaaag
    69061 ctgtagccat ttttaaccct ttctgtgcaa attatggtat aataaagtga tgttattgta
    69121 ccaataagga gaattatgat caactatcca cataaagttt catcacaaaa aagacaaaca
    69181 tctctttctc aacccaaaaa tttcgcaaat cgaggaatgt cttttgaaaa gatgatcaat
    69241 gctaccaacg actactattt gtctcagggc ttggctgtta tacataagaa accaactcct
    69301 attcaaatcg tacaagtgga ctatccacaa cgaagtcgtg ccaagattgt tgaagcctat
    69361 tttcgacaag cttcaacgac ggactattct ggcgtttata atggatatta catcgacttt
    69421 gaagtcaagg aaacaaaaca aaaacgtgcg attccgatga aaaattttca tccacatcag
    69481 attcagcata tggaacaagt ccttgcccaa caaggaatct gctttgtcct tcttcacttt
    69541 tcttctcagc aagaaaccta cttattgccg gcattcgatt tgattcgctt ctatcatcaa
    69601 gataagggac aaaaatcaat gccacttgaa tatattcgag aatatggata tgaaatcaag
    69661 gctggtgcct tccctcaaat tccttatctc aatgttatca aagaacattt attaggtggt
    69721 aaaacaagat gaacaaacca acgattctgc gcctaatcaa gtatctgagc attagcttct
    69781 taagcttggt tatcgcagcc attgtcttag gcggaggagt ttttttctac tacgttagca
    69841 aggctcctag cctatccgag agtaaactag ttgcaacaac ttctagtaaa atctacgaca
    69901 ataaaaatca actcattgct gacttgggtt ctgaacgccg cgtcaatgcc caagctaatg
    69961 atattcccac agatttggtt aaagcaatcg tttctatcga agaccatcgc ttcttcgacc
    70021 acagggggat tgataccatc cgtatcctgg gagctttctt gcgcaatctg caaagcaatt
    70081 ccctccaagg tggatcaact ctcactcaac agttgattaa gttgacttac ttttcaactt
    70141 cgacttccga ccagactatt tctcgtaagg ctcaggaagc ttggttagcg attcagttag
    70201 aacaaaaagc aaccaagcaa gaaatcttga cctactatat aaataaggtc tacatgtcta
    70261 atgggaacta tggaatgcag acagcagctc aaaactacta tggtaaagac ctcaataatt
    70321 taagtttacc tcagttagcc ttgctggctg gaatgcctca ggcaccaaac caatatgacc
    70381 cctattcaca tccagaagca gcccaagacc gccgaaactt ggtcttatct gaaatgaaaa
    70441 atcaaggcta catctctgct gaacagtatg agaaagcagt caatacacca attactgatg
    70501 gactacaaag tctcaaatca gcaagtaatt accctgctta catggataat tacctcaagg
    70561 aagtcatcaa tcaagttgaa gaagaaacag gctataacct gctcacaact gggatggatg
    70621 tctacacaaa tgtagaccaa gaagctcaaa aacatctgtg ggatatttac aatacagacg
    70681 aatacgttgc ctatccagac gatgaattgc aagtcgcttc taccattgtt gatgtttcta
    70741 acggtaaagt cattgcccag ctaggagcac gccatcagtc aagtaatgtt tccttcggaa
    70801 ttaaccaagc agtagaaaca aaccgcgact ggggatcaac tatgaaaccg atcacagact
    70861 atgctcctgc cttggagtac ggtatctacg attcaactgc tactatcgtt cacgatgagc
    70921 cctataacta ccctgggaca aatacccctg tttataactg ggataggggc tactttggca
    70981 acatcacctt gcaatacgcc ctgcaacaat cgcgaaacgt cccagccgtg gaaactctaa
    71041 acaaggtcgg actcaaccgc gccaagactt tcctaaatgg tctcggaatc gactacccaa
    71101 gtattcacta ctcaaatgcc atttcaagta acacaaccga atcagacaaa aaatatggag
    71161 caagtagtga aaagatggct gctgcttacg ctgcctttgc aaatggtgga acttactata
    71221 aaccaatgta tatccataaa gtcgtcttta gtgatgggag tgaaaaagag ttctctaatg
    71281 tcggaactcg tgccatgaag gaaacgacag cctatatgat gaccgacatg atgaaaacag
    71341 tcttgactta tggaactgga cgaaatgcct atcttgcttg gctccctcag gctggtaaaa
    71401 caggaacctc taactataca gacgaggaaa ttgaaaacca catcaagacc tctcaatttg
    71461 tagcacctga tgaactattt gctggctata cgcgtaaata ttcaatggct gtatggacag
    71521 gctattctaa ccgtctgaca ccacttgtag gcaatggcct tacggtcgct gccaaagttt
    71581 accgctctat gatgacctac ctgtctgaag gaagcaatcc agaggattgg aatataccag
    71641 aggggctcta cagaaatgga gaattcgtat ttaaaaatgg tgctcgttct acgtggagct
    71701 cacctgctcc acaacaaccc ccatcaactg aaagttcaag ctcatcatca gatagttcaa
    71761 cttcacagtc tagctcaacc actccaagca caaataatag tacgactacc aatcctaaca
    71821 ataatacgca acaatcaaat acaacccctg atcaacaaaa tcagaatcct caaccagcac
    71881 aaccataaca tttatcaccc agatttttct gggtgatttt gtcatagcac tattgtattt
    71941 atgtgcttaa caaaagcctg agaagatgtc ttctcaggct ttttctgtac tataaacctc
    72001 attggaaaag atagagactg cttccgtaat cttgttaaga ggttttacta aatactagtc
    72061 tttcttcgtt tttactacaa agagagcaga tagggctaga ctaacacttg ctaggaagag
    72121 ggctgtgtca gattgactct cacctgttgc tggcaagatt tgttcaggtg tttctggtct
    72181 agctatttct tgcttataat ctggcgtctt accttgatcg gaaactaaag agctaagttt
    72241 aaactcaggt ttctctacag ttggagcatc tggtttcgta gcagaatctt ttaattggtt
    72301 gagataatct gcaaagtatt ccaccattct ttccgtcaag agatggttat ccgtcgcata
    72361 tttcatgctt gcctgaacgc tagctacttc ctcttgattg tctttgtctg ttaatttctg
    72421 agctttagcc aaagctgctt catagcctga caagtcaaga ggtgtttctg ctacctgtgg
    72481 acgagtaaag atgagttccg ctgcagattg gtatttatcg ccaccatctc cgtaagtctt
    72541 agtacctgta aggacaattt tcttagcctt aattgtctta ccaaaatcaa tgtcttttgg
    72601 cttattgtta tctggccaat cagttgcagt aaaggtatgc tccttgccag actcatctgt
    72661 cacaacaagt ttcacatcac gcaagttacc atttgaacct gatccacgtg gaacgtaacg
    72721 aagtccagtg atttcagttg gttctttcaa gaccatggtt gcaggcttgc ctacatctcc
    72781 accattccaa gatgtatgcc ataaactaga taagtttcca tcaaaggcat ttgcaagacc
    72841 ttcttgagcc tgagcaggag ctgtaagact tgcaaagtca tctgctacca aagccgtttt
    72901 cttctgaacc aaagcattct tcaaggcttc aatcttggca atctctgcac gcgcttcttc
    72961 cacactgata tcatcatcgg cctgactaag gttaaagacc gcctctttca aagcatccat
    73021 agactctttg gtgtagttag tcatggcaac cgttggcaag tagttcttca gagcattttc
    73081 tgtcaacatc ttacctgtta gggtaatttc ttcgatttga agattatcca tcatgaagtc
    73141 gttataacca cggaagttgg catttccacc agaatcacca cgagtattac ttgcattgcc
    73201 agttgagtag atacctaccc aagtatcccc tgtttctgca cctgtcacaa ggaaggttgc
    73261 cttcttggct ttcttagaat ctgtccaagt atttggcaat tcatgcattt ccaagttgct
    73321 tgcttgagtg ccacgacgac ctgactggaa ttctccctta ccgactacaa aagcataggt
    73381 attgtctgaa cctgcttcgt attcaaaggt tacacggtag gtcttacctg cttcaaaacg
    73441 gaagttttgt gggatggttt ggtaaaccaa gttacgacgg ctcactagtc catttgtctt
    73501 gagtgaccaa tttccttcga taacatcatc gactttctta ccgttccaac cacgttgtgt
    73561 atatggatcg tgtttttcag acaagtgagt gcggttgtct tcgacacctt cgacaccacc
    73621 cactacaaat gggaagattc cttgagctac attttcaaag tcttgcttga aggttccttg
    73681 acctgtatcg tgcttgtctc catacatgct tgaattgttt tcaaaggtac gaatttcatc
    73741 aaagtaagtt gcttgatcac cagcttcacg actcaatgtc agagtaacat ttgagacgtc
    73801 cgatcctgtt gtaaagaagg cgtacatgtt ttggaagtaa cttgtatcgt taactgtagc
    73861 attgttacga cgtgtattgt gggcgtaggc ttttacatag ttgagggcga gagacttatt
    73921 ggtataagta gtcacttctt tttcaccagt attcacagtg atacttgcct tggcattact
    73981 acggttatcg acaccgacat aaacggcata cttggtattt ggtttcaagc cagttaattt
    74041 ctgagtgaga ctaacttttt ctttgtttcc ttgaatacga agcatatcgt ttgccccttg
    74101 agacttgaca atttctgcct tagaagcatc gcctgaaatg gtccaatgtt tcaaggtacc
    74161 actgttaaat ccttggtcat agatgtgcat gccttcactc catgacattt caggattggt
    74221 ttgttttgaa cgatagagaa cgtatggttg atttgctaga agatctaggg taattttacc
    74281 atcttttaca gttagttctt gctcttctgt cttaccttgg tcagttagct tgtaaaggta
    74341 aaccttgctc tttgcccaat cgcttggaag ggtccaagtt gttgcaccgg cctgcgtatt
    74401 gaagtagtac atcttttcct tatcagtaga aagtttctta ccatttgcat cccagttcca
    74461 aggagtcaag taagctgaac catcttggat gacacgtccg ttgagagtta ctgtacgttc
    74521 gcgatattgt ggactattga catcatttga cttacgagtt acaactactt tattattgtc
    74581 agcatctacc aattccactc gcatttctgg agtccattta taggtactac cgttatcggt
    74641 catagtcacc ggtgtaccat tttcccattt acttacagtg aagtgttgga agtacttagt
    74701 catgacgtca tgggcaaata agttggttac atagccattg tagtcacttc ttccctgcca
    74761 gccttcaaag tctttcatgc tgtagccacc tagcagtgga tagttggctg caccaccata
    74821 acttctgtag tccccaaccc aagcatcttt ttggtggtta cggataaagc gggtgatggc
    74881 actgttgata cctttattgg tgtagccacc gtaggtcaag tcagctgccc agtgatggaa
    74941 ggtagagtcg tactcaccac catggcccca ctcgatcgca aagcgccagc cttgtttgtt
    75001 aatttcttta gcaagaacgt gggtagccca ggcaccgtta tcacctgatt gaccattacc
    75061 ccaaacgtcc acatagataa agtcgagacc gtcaccaagt tttttcttca aatcttccca
    75121 acgtgccaaa cgaccatgag ctaggtcata ggcagcatca atgttgatac cttgatctag
    75181 ccagttccaa ccatagctat agcttccatc tggattctta cggagaattt tttcattgaa
    75241 gtatttagac tcaggataag tttctgaagc gttaacgtgg atacctagat gagctccata
    75301 tttcttagcc ttctcaatta gggtcttgaa gtcttcgaca ccaccgatac gcttaccaat
    75361 atcagcatag ttcaagtgac cagagtcatg gccttcgcta ccatatcctt taaggaaaac
    75421 accttgccca agaccatctg tgtggagatt gattttcttg ataccatcca aggtcataag
    75481 gaatggattt tgtgcttgag aaccaaagtt catcgcgata cggtaagctg tgatatcctt
    75541 aactttttcc caaccttgag gattgttcat aatgctacga taagcaatgg caccatcttg
    75601 ccaatcgact ttcttgtctg cattggcatc ttcagtgata acaaccttag cacttggaag
    75661 ttccttcgtg tattctggga aaacaatgcc cttataagct ttttcccatt gccattcaga
    75721 gctgtggatt cctacatagt tggcatttcc gactgtttct ttataagctg tcaaacgagt
    75781 ccagtcattc gaaccaccac catagctatt ttgagagtta ctccaaacac cagcagcaag
    75841 cttatctgta gaaacaaatc catacatgta acccttggct aggtctttca ttggattggt
    75901 tacatcgata tgatcatctc cgctgacatg cgtattgttt gacatggttg ccccatcaaa
    75961 cttagcacca gtttgatcac tagaaacaga gactaaagca ttgccgagga aactaataga
    76021 agaaagtagt tttctttcgt catcaatctt ttgacctgga gtgacttgat tgtggttgac
    76081 aatcttggtc acatcaaagt gcaattgatt gtccacaact tgcaagcgta ctgtcatttc
    76141 cgcattgatt aagtgagcat catcgcgaag cttcatcaag tactctgctg ttgtctcatt
    76201 gattttctta taagtgactt caggggtgat tcggtggtta ttgataaaga cttggttgaa
    76261 ctgttgcacc tgtcctggca aagtatgtcc attcaagctg tattccttga cacgagggaa
    76321 ggcttggtca atcactgctt tgaggacctt agactggatc gtatcataag tcaccttgct
    76381 atcgtcaaca accggacctg tttctttctg ggcaggagta tcatccgctt ttacgccttc
    76441 ttgattgtct gttttaacgc tgacaactgt acggtcattg ccataagttc ctgccttgag
    76501 aaggatcttc ttctcatttt taagattatc attgaccgcc ccaggcagtg tcactgtgtc
    76561 aaagagattg acatcgttat tgctggcatt gagttgtcca tctgacttga gagtgataga
    76621 aagacggttt acagaacccg gttctggtgc aactacacgg ttgcctttat accatgtgct
    76681 attacctgga gttttgtatt cccagaacca gccatccttg tcataaccga caaaaacatt
    76741 attattggta tctttaaatt tcaggaagac accaaagcgt gatttgccct tttcagaatc
    76801 ttctttgaag gttaaatcaa cagttgcatt tccattggca tcaacggtca agcccttctt
    76861 ttcaaacagg gctggtttgc ctgcgttatc attttgagca gttgagaata gttggttgta
    76921 gcggacacct ttttcttctc ggatagtgac tgttccctgt tgttcttttt tctctaccgt
    76981 ttgccattca ggagttaccg tcttaggtgt ttcaggttta gcagctgcag gtttatcctc
    77041 ttttggtttt tcttcagccg gtttttcttt ttcaagtgct aatagttctt cttctgtctt
    77101 aggtccatct gtaacttctg gagaaccttg gtcttctccc accttaggcg cttcaaaatc
    77161 acgcccatca ttctcgtttg ctgttgcaag agcagtagct aaatcagctg gtaagttcgc
    77221 cgtggaacca gactgcacgc tatctgcaag aaccggactt gtcccaaaga atgcagctcc
    77281 aatcataaca gaagcaacac ctaatgaaaa tttccgaata ctatatttac aacgtttttc
    77341 aaataatcct ttattcataa acttctaaat cctttcattt tttagcaagc gtttacattt
    77401 cctttttaaa aaatactcct tcctctgaaa gtgcaatgct taaccctgat aaataaaaaa
    77461 taattgtact tttaatataa caaataatag ctgagaaagc aataggaaac aagtaaaatt
    77521 aacaaaaatt ttctctattc tgacaaaaag aggctccaac ttttgggggt cagtacattt
    77581 agaatctttc tttacaaatg taaaaaagga ttcagcattc aagagaaata ctaaatcctt
    77641 tcttatattt tgcaacagtt atttcacatg ttttgcgaga tcttcttgag cctttttatt
    77701 agactcttct ttttctttca tccatttttc ctgagctttt tggtattcat ctacagtgac
    77761 tgccttgtct tgaagttcca agtatttata caagactggt tcacttgtac ctttatttcc
    77821 tgacaatgca aatggtattg taaatggtac catcttagac aagattgggc gccctgtacg
    77881 agatgtagtt ggaataatca aagcactatc tgtcaaccaa gcttgggctg cagcgtattt
    77941 atcatagcgt ttagcaacat ctgtagcctc atcaccagcc tcagtgacca atttttcgta
    78001 gtcatataga cctacttttt tagcagctac attatcttcc cctgagtcaa accctaaata
    78061 tgttttagta ctttctccta cagaaggttt gataatatca aggtaggttg atggatcggc
    78121 aaagtctgga ccccaaccga cattatctga taaatcccag tcttcgccag cagcattttc
    78181 agcaaaatat gtaatattgt ttacttcgtc tttttgtagt tgttggatat caataatgac
    78241 attatcagct cctaaagttg cttccaagga ttgtttcata gattggacgc gctgaacttt
    78301 tgtagttgct gtctggtcaa ctggcatatc caaatgaatt gggaaagtca caccttctgc
    78361 ttgtaaggct gatttagctt tagcaaattc agccttggct ttttctggat tgtaaagacc
    78421 atcctgagaa tctgcaagat taacatcctt ccattcatcc ccataagtga ccaatttctc
    78481 tttgaccata tcgccaaagt ttttaccatc tgcttgaaca aatgttggtg gaacaaagat
    78541 attacgtaag attttgcttg ctccagtttg tccattcaac tgagaggcat aggctgtacg
    78601 atcaaaacca aaggcaatag cctgacggaa atccttgttt aagagagcct ttttagtcga
    78661 tgccttttgt tcgtcgctgg tcttagatgt atatttatag gactgacggt caatatttgt
    78721 accaactaga tacgtaatag agccttgttg agtatagaca atattgtcct tcatactctt
    78781 ctcaagctct gcgaaacttg cacttgttgg atagagacga gctgctgtaa ggctaccatc
    78841 tttaaagttt tctgcaggtt tgctggtatc ttgaccatcc cagaatgaca atttaacttt
    78901 gtcaacatgc acattgtcct tatcccagta gttcggattt ttcgcaaatt caacagagga
    78961 ttttgtcaca atggatttca acaaataagg accgttatac aagagactac ttggatccgt
    79021 cgctttggca aaatcatccc cttttgagtt caaaaactct tcattaactg gcgcaagcac
    79081 acccatggtt gtcttagaat tccagaagct ttctggtttg ttcaaagtgt actgaactgt
    79141 ctgatcatcc aaagccttaa ttcctacttg tgagaaatct ttgatttccc cttttacata
    79201 ggcatccaac cctttgattg attcttgaac aaggtaaaga gcatctgatt ttttatcagc
    79261 agcatatttt agtcctgtta caaagtcttg agctttgact gccgcgtatt cttcaccttc
    79321 agaagtatac cattttgcat ccttacggat agtataagtg taagtcaatc catccttgga
    79381 tacagaccaa tcctcagcca tagacggcac aaagttcccg tagcgatcat tttctagcaa
    79441 accatcaacc acgttactgg taatatttgc tgtcgcagcc ttagcagttg tcaaatagtt
    79501 gaggttatca gggtctgtct cataaatgta tgagaatgtc ttctcacctt tagtgcttga
    79561 acctgatcca gagcatgcag ctaaagtagt cgccgccaat aatgtcacgc ccgcaagggc
    79621 aagtagtttt gaacttttca tccttttctc ctttaaaact ttctctccat tatagactct
    79681 tttcagaaag ttgtcaacag aattttcaga atttttgaaa attatttttc aaataacatc
    79741 tttgcaaaaa atatgaatat cgtaaccgcc caataacgaa gtctattgaa aaatctccag
    79801 actagagaac tcacggatag ttcctaatct ggagatttct tatttgcact tttcttgtac
    79861 aactttagtc cacggtaaat aggcctctaa aatctctttg tttacgagag tttcctcgtt
    79921 tggaagacat tctagaagat aggatagata tttctcgcta tttaattata atagctcttg
    79981 ctttagctcc ttcaaaactt tgagaaaata accaccctcg cttttttaaa ctgagcttag
    80041 gctaaaagag tccactggac tcttttactc cgtcccataa ccaatgattt aatggcgcat
    80101 tcagctagat tattggaaag gaccagatgt ccgtctttca aaatagtctt aaaggtttct
    80161 tcatacttga ggctgtattc aattgccctt cctagttttg aacctgctaa aactgactga
    80221 cgccggcacc aagcaaagaa gtcttccatt aggggctgga gatgttcttg acgtttctgt
    80281 agtcgttcat cagctggcaa agcctcccag tctctttcca gggaaaataa ctgatcacaa
    80341 taagctaaac ctttagctcc taaggatgat ttatccgttt gcttgggggg cgcttcaaaa
    80401 aacttccttc tcacatgtgc ccaacatcca acaagttcag cttcttccag ttgacgataa
    80461 gcttctagcg gttcgcagtt taccaagctt agcgtcgcct tgctcctaaa ccttggactg
    80521 ctatcgcata ggcagaacta gaggactaaa gtcctaagtt actgccgcaa catatcacaa
    80581 tgcacatagc cagaataatc tcctaggaat tcttgtacta ctaaaccact ccgacgctga
    80641 tcatggtggt acagcgtgat tgcttgattc tcagctttcc cagacaaaaa agtccaatag
    80701 taggtcagat ggctatcact ctctagaacc cgataagagg tttcatccgc atgaagaaga
    80761 ggttgttcta acaacttttc tcgtaaaagc ttataaaggg actctaaata gtattgactt
    80821 gccttgatat gccaattaga gatttcctta cgtgtgattg gtaaacccat cctagcccaa
    80881 tcttcttctt ggcgataatt gggtaccttc agattaaact tctgatggat ggtgtgagcg
    80941 ataatagaaa ctgagccaaa gctatgcacc aaagagacca gcaccaacaa caagataatt
    81001 gtacatctta agctcctttg gagttcatta tctgcctctt ttattagact agaaaatcat
    81061 tctactactt atctcacttc ttgtttgtaa aattcttgca atgcatcttg ccaagttgga
    81121 ataacaaatc cagtagcttt ggctttggcc aggctcatcg ttgagtttag cggacgttga
    81181 gctttggctg gaaattgact ggaatctact ggcttgactt cgacatctgt atctttcaaa
    81241 atttcaactg caaaatcata ccatgttgtg tcttctgtcg catcatttga caaatgataa
    81301 taaccaaatt ccttacgatt ttcagctagg tagatcatga attcagccaa ggtacgagtc
    81361 caagtcggac gaccgtactg gtcatttaca actgttaaag tcttatgagt tttcgcaaga
    81421 ttttgcatgg taaaaacgaa gtttttgcca taatttccaa atacccaggc agtacggata
    81481 atatagaaat tagacacatg cttctcaact aactcttccc ccatacgctt agtgcgtcca
    81541 tattctgtct gtggatctgg tcggtcatca acttcccact cttgtccaac tggtttctta
    81601 ccgtcaaaga cctagtccgt agaaatataa actagagttg caccatgctt ttcagatgct
    81661 tttgcgacat tttttgtccc catcacattg atggcgaagt ccaactcttt tccttcatcc
    81721 tctgctgcat caacagcggt gtaggctgca caatggtaga ctaaagtcgg tttcacctct
    81781 tcaaaaactt tctcaaccat ttcttcattg gtaatgtcca tctcagccac atctactgcc
    81841 acgtattctt cattacgttc atccaataaa tagcgaagtt ccgttcctaa ttggccattt
    81901 gcccctgtaa ttaaaatcat ctctagacct ttctaatatg taactcttcc caatatagca
    81961 ataaaaagca gcgatttcct gctttttata ctgtaataat ctcctgagtc ttagcataat
    82021 tggcttcaac agcttctttt tctgctttcc accattcttg gttatctgta taccacttga
    82081 ttgttgcctt gagcccagct tcaaagttgg taaattcagg tttccacccc aactcatcac
    82141 ggagcttgct ggcatcaatc gcatagcgaa ggtcatgtcc tgcacggtca gtcacatgat
    82201 cataggcatc cgtagcttgt cccatttcct taaggataag ttccaaaact tccttattgt
    82261 tcttctcacc atcagcccca atcaagtagg tttcaccgat ttgccctttt gtcaagattg
    82321 tccaaactcc tgaagaatgg tcattggtat gaatccagtc acgaacgttc ttaccttcac
    82381 cgtaaagttt tggcttaatt ccacttagga tgttagtaat ctgacgtggg atgaattttt
    82441 cgatatgttg ataaggaccg tagttatttg aacagttgga aatcgttgcc ttgactccaa
    82501 aagaacgcac ccaggctttg acaatcaagt ctgatgcggc cttggttgat gagtacggag
    82561 agcttgggtt gtattttgtt tcagcagtaa atttctcacc tggtccttca ccatgacctg
    82621 gcaaatcttc tcgtaaaggg agatccccat aaacttcatc tgtcgataca tggtggaagc
    82681 gaatatcata cttacgagca gcttctaaaa gagtatagat tccaatgaag ttagtatgaa
    82741 taaatggcga tggatcattg agcgaattat cattgtggct ttccgctgca taatgaacga
    82801 tagcatctgc ttgagcaacc aacttgtcta ccaactccgc atcagcaatg tcaccaacaa
    82861 ctaactcaac acgattgcct aaaatttcct caatattcgc gcggtttcca gcataagtca
    82921 acttatctag gactgtcacg tgaacatctg gaaagttctc gtaaacataa tggacaaagt
    82981 tagaaccgat aaagccagct ccacctgtca cgataatatt tttgtattca gtcatattct
    83041 ttccttattc caaatcttct tttttcaaag gcttcacgtc cttaagtagg ggatgatgtt
    83101 tgtctgcttc agatacgtct gcttcttcca gattttccca ttcaatacca aggcttggat
    83161 cagcgtagtt cacaaaggca tacttgggtt tgagttcaag agcccagtaa tcattgacca
    83221 gatagctata tgacactgta tctgataaaa cttggaagcc attagctacg cctcgaggaa
    83281 caaagattcc cttgcttgca tcaattactg tctgataggt attcccaaag gtttcaccct
    83341 cgcgtagatc aacccaagaa cccagaactt tccctccatc tgctacagag atgtacttat
    83401 cccaaggctc tgcgtggagg cctcgaagga catttttacg tgagaaggat acattgtttt
    83461 gcaattttcc ttctgcaaag aaagactctg gaaatccaag tggaagcact ttttcctttt
    83521 ggaaattttc tttaaaccag ccacgattat ctccatgaac ggggatatca aactccaaca
    83581 tgcctggaat agcttcaacc ttgcgtgccg caagcgtctt accgaaaaaa ttatctgtca
    83641 tctatgcttc tccaatcaaa cggagcagat actgtccgta ttcatttttc ttaagtggtt
    83701 gggctaaggc caatacatct tctcgactga tatagcccat acggtaagca atttcttcta
    83761 agtttgctac ctgaacattt tgcatccgtt gcactgtttc gatgtactgt gaagcctcta
    83821 gtaaactttc atgagttcca gtattcagcc aagcaaagcc acgtcccata agctcaacag
    83881 acaaatcacc acgatctagg taagccttgt ttacatctgt aatttccagt tcaccacgag
    83941 ggcttggttt aatactcttg gcaatttcga caacatcgtt atcatagaaa tacagtcctg
    84001 tcactgcata gttggagcga ggatactccg gtttttcttc tatggaaata gcattcatgt
    84061 ctgtatcaaa ctcaaccaca ccaaaacgct ctggatcctt cacttggtag ccaaaaacag
    84121 tcgcaccttt ctctttcttg gctgcttttt gaagcattgt gctcagacca ggaccatggt
    84181 agatattgtc gcctaaaatc aaggcaacgc tatcgtcaga aataaactct tccccaattg
    84241 ccaaaccatc tgtacttggt tgctctgcat aagaaagttt gatcccaaac tcagatccgt
    84301 cttgaagaag ctcttgaaat cgatgtaaat cctgtggagt ggaaataatc aaaatatccc
    84361 taatcccagc caacatcaat gttgaaagtg ggtagtaaat catcggttta tcataaaccg
    84421 gcataagttg ttttgacgca gcgcgagtca aaggatataa acgtgtcccc gaaccacctg
    84481 ctagaataat acctttcata gtagggtacc tttctttgtt attttagagt caattactat
    84541 taattgtgta ctgctctaaa aagaaaacaa tcatcccatg ttttatatgg ctctataata
    84601 tttgtagtgg gtaaatccac tatagatatt atggagccta ttttattgta gaaaaaaagt
    84661 cccataagat ctataatgaa aagcgaccaa acaactcatt agaaagattc atatgggaca
    84721 attacatttt atcacaaaac t
//
LOCUS       DAVBEO010000003        83156 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 009
            SAMEA1678075-rid20185393.denovo.003, whole genome shotgun sequence.
ACCESSION   DAVBEO010000003 DAVBEO010000000
VERSION     DAVBEO010000003.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678075
            Sequence Read Archive: ERR226392
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 83156)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 83156)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980207.1
            Genome Coverage       :: 150x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:50:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 72 of 147
            Pseudo Genes (incomplete)         :: 72 of 147
            Pseudo Genes (internal stop)      :: 42 of 147
            Pseudo Genes (multiple problems)  :: 32 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..83156
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678075-rid20185393.denovo.003"
                     /strain="KS 009"
                     /db_xref="taxon:1313"
     gene            51..299
                     /locus_tag="VQ543_000199"
     CDS             51..299
                     /locus_tag="VQ543_000199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001858369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2611000.1"
                     /translation="MVSSSGSEFQSGWQEHQLIAEKVSKTLDKTFDKDVREIPTSQFY
                     QKFVDEMGRIYSGNLILQELITVNGAYKATYIGELSSN"
     gene            430..1602
                     /locus_tag="VQ543_000200"
     CDS             430..1602
                     /locus_tag="VQ543_000200"
                     /EC_number="2.3.3.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004181031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA synthase"
                     /protein_id="HET2611001.1"
                     /translation="MTIGIDKIGFATSQYVLKLQDLAEARGIDPEKLSKGLLLKELSI
                     APLTEDIVTLAASASDSILTEQERQEVDMVIVATESGIDQSKAAAVFVHGLLGIQPFA
                     RSFEIKEACYGATAALHYAKLHVENSPESKVLVIASDIAKYGIETPGEPTQGAGSVAM
                     LITQNPRMMAFNNDNVAQTRDIMDFWRPNYSTTPYVNGVYSTQQYLDSLKTTWLEYQK
                     RYQLTLDDFAAVCFHLPYPKLALKGLKKIMDKSLPQEKKDLLQKHFDQSILYSQKVGN
                     IYTGSLFLGLLSLLENADSLKAGDKIALYSYGSGAVAEFFSGELVEGYEAYLDKDRLN
                     KLNQRTALSVADYEKVFFEEVNLDETNSAQFAGYENQDFALVEILDHQRRYSKVEK"
     gene            1602..2876
                     /locus_tag="VQ543_000201"
     CDS             1602..2876
                     /locus_tag="VQ543_000201"
                     /EC_number="1.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000704367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA reductase,
                     degradative"
                     /protein_id="HET2611002.1"
                     /translation="MKISWNGFSKKSYQERLELLKAQALLSPERQASLEKDEQMSVTV
                     ADQLSENVVGTFSLPYSLVPEVLVNGQEYTVPYVTEEPSVVAAASYASKIIKRAGGFT
                     AQVHQRQMIGQVALYQVANPKLAQEKIASKKAELLEFANQAYPSIVKRGGGARDLHVE
                     QIKGEPDFLVVYIHVDTQEAMGANMLNTMLEALKPVLEELSQGQSLIGILSNYATDSL
                     VTASCRMAFRYLSRQKDQGREIAEKIALASQFAQADPYRAATHNKGIFNGIDAILIAT
                     GNDWRAIEAGAHAFASRDGRYQGLSCWTLDLEREELVGEMTLPMPVATKGGSIGLNPR
                     VAFSHDLLGNPSARELAQIIVSIGLAQNFAALKALVSTGIQQGHMKLQAKSLALLAGA
                     SESEVAPLVERLISDKTFNLETAQRYLENLRS"
     gene            complement(2912..3877)
                     /locus_tag="VQ543_000202"
     CDS             complement(2912..3877)
                     /locus_tag="VQ543_000202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002929307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HET2611003.1"
                     /translation="MVAKLTDVAKLAGVSPTTVSRVINKKGYLSEKTIQKVNEAMREL
                     GYKPNNLARSLQGKSAKLIGLIFPNISNVFYAELIDKLEHQLFKNGYKTIICNSEHDS
                     EKEREYIEMLEANQVDGIISGSHNLGIEDYNRVTAPIISFDRNLSPDIPVVSSDNYAG
                     GVLAAQTLVKTGAQTIIMITGNDNSNSPTGLRHAGFASVLPKAPIINVSSDFSPVRKE
                     MEIKNILTREKPDAIFASDDLTAILVIKIAQELGISVPKELKVIGYDGTYFIENYYPQ
                     LATIKQPLEEIACLTIDLLLQKIEGKEVATTGYFLPVTLLPGKSI"
     gene            complement(3858..5312)
                     /locus_tag="VQ543_000203"
     CDS             complement(3858..5312)
                     /locus_tag="VQ543_000203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32 protein"
                     /protein_id="HET2611004.1"
                     /translation="MEWTTERRYRLYQDWTQEEIQHIKENMAQSPWHTHYHVEPKTGL
                     LNDPNGFSYFDGKWILFYQNFPFGAAHGLKSWAQLESDDLVHFKETGIKVLPDTPLDS
                     HGAYSGSAMQFGDNLFLFYTGNVRDENWIRHPYQIGALMDKEGKITKIDKILIDQPAD
                     STDHFRDPQIFNFKSQYYAVVGGQDLEKKGFVRLYKAVNNDYTNWQAVGDLDFANDRT
                     AYMMECPNLVFVEEHPVLLYCPQGLDKKVLDYDNIFPNMYKIGASFDPKNAKMVDVSQ
                     LQNMDYGFEAYATQAFNAPDGRALAVSWLGLPDVSYPSDRFDHQGTFSLVKELTIKDD
                     KLYQYPVAAIKDLRASEEAFSNRSQTKNTYELELNLEANSQSEIVLLADKEGKGLSIN
                     FDLVNGQVTVDRSQAGEQYAQEFGTTRSCPIENQATTATIFIDNSVFEIFINKGEKVF
                     SGRVFPHADQNGILIKSGNPTGTYYELDYGRKTN"
     gene            5689..7572
                     /locus_tag="VQ543_000204"
     CDS             5689..7572
                     /locus_tag="VQ543_000204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HET2611005.1"
                     /translation="MNNQEIAKKVIDALGGRENVNSVAHCATRLRVMVKDEEKINKEV
                     IENLEKVQGAFFNSGQYQIIFGTGTVNKMYDEVVVLGLPTSSKDDMKAEVAKQGNWFQ
                     RAIRTFGDVFVPIIPVIVATGLFMGVRGLFNALEMPLPGDFATYTQILTDTAFIILPG
                     LVVWSTFRVFGGNPAVGIVLGMMLVSGSLPNAWAVAQGGEVTAMNFFGFIPVVGLQGS
                     VLPAFIIGVVGAKFEKAVRKVVPDVIDLLVTPFVTLLVMSILGLFVIGPVFHVVENYI
                     LIATKAILSMPFGLGGFLIGGVHQLIVVSGVHHIFNLLEVQLLAADHANPFNAIITAA
                     MTAQGAATVAVGVKTKNPKLKTLAFPAALSAFLGITEPAIFGVNLRFRKPFFLSLIAG
                     AIGGGLASILGLAGTGNGITIIPGTMLYVGNGQLPQYLLMVAVSFALGFALTYMFGYE
                     DEVDATAAAKQAEVAEEKEEVAPAALQNETLVTPIVGDVVALADVNDPVFSSGAMGQG
                     IAVKPSQGVVYALADAEVSIAFPTGHAFGLKTRNGAEVLIHVGIDTVSMNGDGFEAKV
                     AQGNKVKAGDVLGTFDSNKIAAAGLDDTTMVIVTNTADYASVAPVATGSVSKGDAVIE
                     VKI"
     gene            7721..8608
                     /locus_tag="VQ543_000205"
     CDS             7721..8608
                     /locus_tag="VQ543_000205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000164317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HET2611006.1"
                     /translation="MTKLYGSLEAGGTKFVCAVGDENFNVVEKTQFPTTTPIETIDKT
                     IEFFSKFDNLAGLAVGSFGPIDIDKNSKTYGFITTTPKPNWANVDLLGALRRALNVPM
                     YFTTDVNSSAYGEMVARNNAGGRIENLVYYTIGTGIGAGVIQRGEFIGGVGHPEMGHY
                     YVARHPMDIEKEFKGVCPFHKGCLEGYAAGTSLEARTGVRGETIELNNPVWDVQAYYI
                     AQAAVNATVTFRPDVIVFGGGVMAQQHMLDRVREKFTSLLNGYLPVPDVRDYIVTPAV
                     AGNGSATLGNFVLAKEVSK"
     gene            complement(8928..9545)
                     /locus_tag="VQ543_000206"
     CDS             complement(8928..9545)
                     /locus_tag="VQ543_000206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000076166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HET2611007.1"
                     /translation="MSQDKQMKAVSPLLQRVINISSIVGGVGSLIFCIWAYQAGILQS
                     KETLSAFIQQAGIWGPPLFIFLQILQTVVPIIPGALTSVAGVFIYGHIIGTIYNYIGI
                     VIGCAIIFYLVRLYGAAFVQSVVSKRTYDKYIGWLDKGNRFDRFFIFMMIWPISPADF
                     LCMLAALTKMSFKRYMTIIILTKPFTLVVYTYGLTYIIDFFWQML"
     gene            complement(9960..10148)
                     /locus_tag="VQ543_000207"
                     /pseudo
     CDS             complement(9960..10148)
                     /locus_tag="VQ543_000207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001153868.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            complement(10658..10738)
                     /locus_tag="VQ543_000208"
                     /pseudo
     CDS             complement(10658..10738)
                     /locus_tag="VQ543_000208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            10854..11747
                     /locus_tag="VQ543_000209"
     CDS             10854..11747
                     /locus_tag="VQ543_000209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2611008.1"
                     /translation="MLEVRSLEKSFGSKQVLFGIDFQARPGRILGLVGKNGAGKTTIF
                     HSILKFLEYQGEIGLDGQDIRQETYARIGYLPEERSLMPKLTVLEQVRYLATLKGMDA
                     KEVKEKLPQWMKRLEVKGKLTDKIKSLSKGNQQKIQLIITLIHEPDLIILDEPFSGLD
                     PVNTELLKQVIFQEKERGATIIFSDHVMTNVEELCDDILMIRDGRVVLHGPVQDVRNQ
                     YGKTRLFVSSERSKEELENLPHVKQVSLTKQGSWKLILEDESAGRELFPILTQGQYIA
                     TFDQQAPTIDEIFKLESGVEV"
     gene            11744..12943
                     /locus_tag="VQ543_000210"
     CDS             11744..12943
                     /locus_tag="VQ543_000210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001245382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET2611009.1"
                     /translation="MRNMWVVIKETYLRHVESWSFFFMVISPFLFLGISVGIGHLQGS
                     SMAKNNKVAVVTTVPSVAEGLKNVNGVNFDYKDEASAKEAIKEEKLKGYLTIDQEDSV
                     LKAVYHGETSLENGIKFEVTGTLNELQNQLNRSTASLSQEQEKRLEQTIQFTEKIDEA
                     KENKKFIQTIAAGALGFFLYMILITYAGVTAQEVASEKGTKIMEVVFSSIRASHYFYA
                     RMMALFLVILTHIGIYVVGGLAAVLLFKDLPFLAQSGILDHLGDAISLNTLLFILISL
                     FMYVVLAAFLGSMVSRPEDSGKALSPLMILIMGGFFGVTALGAAGDNLLLKIGSYIPF
                     ISTFFMPFRTINGYAGGAEAWISLAITVIFAVVATGFIGRMYASLVLQTDDLGIWKTF
                     KRALSYK"
     gene            complement(13296..14063)
                     /locus_tag="VQ543_000211"
     CDS             complement(13296..14063)
                     /locus_tag="VQ543_000211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000498762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2611010.1"
                     /translation="MFWNLVHYEFKNVNKWYLALYAAVLVLSALIGIQTQGFKNLPYQ
                     ESQATMLLFLATVFGGLMLTLAISTIFLIIKRFKGSVYDRQGYLTLTLPVSEHHIITA
                     KLIGAFIWSLISTAVLALSAVIILALTAPEWIPLSYVITFVETHLPQIFLTGISFLLN
                     TISGILCIYLAISIGQLFNEYRTALAVAAYIGIQIVIGFIELFFNLSSNFYVNSLVGL
                     NDHFYMGAGIAIVKELIFIAIFYLGTYYILRNKVNLL"
     gene            complement(14080..14775)
                     /locus_tag="VQ543_000212"
     CDS             complement(14080..14775)
                     /locus_tag="VQ543_000212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2611011.1"
                     /translation="MSLLVFENVSKSYGATPALENVSLDIPAGKIVGLLGPNGSGKTT
                     LIKLINGLLQPDQGRVLINDMDPSPATKAVVAYLPDTTYLNEQMKVKEALTYFKTFYK
                     DFNLERAHHLLADLGIDENSRLKKLSKGNKEKVQLILVMSRDARLYVLDEPIGGVDPA
                     ARAYILNTIINNYSPTSTVLISTHLISDIEPILDEIVFLKDGKVVRQGNVDDIRYESG
                     ESIDQLFRQEFKA"
     gene            complement(14780..15145)
                     /locus_tag="VQ543_000213"
     CDS             complement(14780..15145)
                     /locus_tag="VQ543_000213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HET2611012.1"
                     /translation="MSWTFDNKKPIYLQIMEKIKLQIVSHTLEPNQQLPTVRELASEA
                     GVNPNTIQRALSDLEREGFVYSKRTTGRFVTKDKELIAQSRKQLSEEELEHFVSSMIH
                     FGYEKEELPGVVSDYIKGV"
     gene            15285..15758
                     /gene="nrdR"
                     /locus_tag="VQ543_000214"
     CDS             15285..15758
                     /gene="nrdR"
                     /locus_tag="VQ543_000214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001203675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor NrdR"
                     /protein_id="HET2611013.1"
                     /translation="MRCPKCGATKSSVIDSRQAEEGNTIRRRRECDECQHRFTTYERV
                     EERTLVVVKKDGTREQFSRDKIFNGIIRSAQKRPVSSDEINMVVNRIEQKLRGRNENE
                     IQSEDIGSLVMEELAELDEITYVRFASVYRSFKDVSELESLLQQITQSSKKKKER"
     gene            15759..16928
                     /locus_tag="VQ543_000215"
     CDS             15759..16928
                     /locus_tag="VQ543_000215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000802368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation and membrane attachment
                     family protein"
                     /protein_id="HET2611014.1"
                     /translation="MKPIDRFSYLKNNRVSQDTSSLVQCYLPIIGQEALSLYLYTISF
                     WDNGRKEYLFSSILNHLNFGMDRLIKSLKILSAFNLLTLYQKGDVYQLALHAPLSSQD
                     FLEHPVYRRLLEKKIGDSAVEDLKVESADGEEIPVSLNQVFPELAELGSQEDLGLKKK
                     VANDFDLEHFRQLMARDGLRFADEQSDVLNLFAIAEEKKWTWFETYQLAKSTAVSQVI
                     STKRMREKIAQKPVSSDFNPKEATIIKEAKSKTALQFLAEIKQTRKGTITQTERELLQ
                     QMAGLGLLDEVINIILLLTFNKVDSANINEKYAMKVANDYAYQKIHSAEEAVLRIRER
                     GQKTKTQKQNQTAPAKTNIPKWSNPDYKNETSEETRLELERKKQELLARLEKGGD"
     gene            16929..17825
                     /gene="dnaI"
                     /locus_tag="VQ543_000216"
     CDS             16929..17825
                     /gene="dnaI"
                     /locus_tag="VQ543_000216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein DnaI"
                     /protein_id="HET2611015.1"
                     /translation="MESVGDVLKRQPSRFYYQDLVQKIMKDPDVAAFIQQESLTPEEL
                     NRSISKFNQYITERDKFLRGDTDYIAKGYKPILVKNHGYADVSYEETPELIAAEKEAA
                     IKNRLKLINLPASLKKASLAQVDLDDLGRLPVFEKLLAFVEQYPAIRKGLYLYGDFGV
                     GKSFMVAALAHDLSEKRGVSSTLLHYPSFVIDVKNAISDGNVKTLVDEIKLSEVLILD
                     DIGAEQSTAWVRDEILQVILQYRMQENLPTFFTSNFNFEDLEKHFAKVKHGNDETWEA
                     RRVMERIRYLAEETRLEGVNRR"
     gene            17822..18535
                     /locus_tag="VQ543_000217"
     CDS             17822..18535
                     /locus_tag="VQ543_000217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000140867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent oxidoreductase"
                     /protein_id="HET2611016.1"
                     /translation="MTETIKLMKAHTSVRRFKEQEIPQVDLNEILTAAQMASSWKNFQ
                     SYSVIVVRSQEKKDALYELVPQEAIRQSAVFLLFVGDLNRAEKGARLHTDTFQPQGVE
                     GLLISSVDAALAGQNALLAAESLGYGGVIIGLVRYKSEEVAELFNLPDYTYSVFGMAL
                     GVPNQHHDMKPRLPLENVVFEEEYQEQSTEAIQAYDRVQADYAGARATTSWSQRLAEQ
                     FGQAEPSSTRKNLEQKKLL"
     gene            18549..19859
                     /gene="der"
                     /locus_tag="VQ543_000218"
     CDS             18549..19859
                     /gene="der"
                     /locus_tag="VQ543_000218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018377046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase Der"
                     /protein_id="HET2611017.1"
                     /translation="MALPTIAIVGRPNVGKSTLFNRIAGERISIVEDVEGVTRDRIYA
                     TGEWLNRSFSMIDTGGIDDVDAPFMEQIKHQAEIAMEEADVIVFVVSGKEGITDADEY
                     VARKLYKTHKPVILAVNKVDNPEMRNDIYDFYALGLGEPLPISSVHGIGTGDVLDAIV
                     ENLPNEYEEENPDVIKFSLIGRPNVGKSSLINAILGEDRVIASPVAGTTRDAIDTHFT
                     DTDGQEFTMIDTAGMRKSGKVYENTEKYSVMRAMRAIDRSDVVLMVINAEEGIREYDK
                     RIAGFAHEAGKGMIIVVNKWDTLEKDNHTMKNWEEDIREQFQYLPYAPIIFVSALTKQ
                     RLHKLPEMIKQISESQNTRIPSAVLNDVIMDAIAINPTPTDKGKRLKIFYATQVATKP
                     PTFVIFVNEEELMHFSYLRFLENQIRKAFVFEGTPIHLIARKRK"
     gene            19950..20285
                     /locus_tag="VQ543_000219"
     CDS             19950..20285
                     /locus_tag="VQ543_000219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2611018.1"
                     /translation="MEHLFKFLLLAPYFYFDNWIEKANRNSKFFPIFYYFYWFYIPFY
                     SLFSLAWTVVSVLFFNTVLRNVTDIKLWGIWFLFILLAIGMNWLTYSCFKEMFRLRQE
                     LGKSKGGRH"
     gene            20425..20760
                     /locus_tag="VQ543_000220"
     CDS             20425..20760
                     /locus_tag="VQ543_000220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2611019.1"
                     /translation="MEYLFKMIILLPCFYFFSWIEKANRDSKIFPIFYYFYWIYITLY
                     ALFSLAWTVFSVLFFNIVLRNLTDIKLWGIWLLLLLIAFASDWLDYICFKKMLDLRRE
                     LGKSKGGRH"
     gene            20945..21736
                     /locus_tag="VQ543_000221"
     CDS             20945..21736
                     /locus_tag="VQ543_000221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2611020.1"
                     /translation="MKIPLLTLARHKFVYVLLTLLFLALVYRDVLMTYFFFDIHAPDL
                     AKFDGQAIKNDLLKSALDFRILQFNLGFYQSFIIPIIIVLLGFQYIELKNKVLRLSIG
                     REVSYQGLKRKLTLQVASIPCLIYLVTVLIIAIITYFFGTFSPLEWNSLFSDGSGLQR
                     LLDGEIKSYLFFTCVLLIGIFINAIYFLQIVDYVGNVTRSAITYLMFLWLGSMLLYSA
                     LPYYMVPMTSLMQASYGDVSLMKLFTPYILYVVPYMVLKKYEDNV"
     gene            21729..22370
                     /locus_tag="VQ543_000222"
     CDS             21729..22370
                     /locus_tag="VQ543_000222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000475766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2611021.1"
                     /translation="MFKNFNNIWLKRKIVLLLRIVLMMILINYLLSTAVQKQDAVIFF
                     KRELISIFSYNDYSEANLEIPKLLLNLSLFMVGWLSVILLESDLADHYHHLIRYQSSS
                     FFDYTRKRLVVISKFFTQDLFVWFLGLLPLGIHFKTVALFFLLAQLMMLYLLLSYLIA
                     LISAGAGFSFFLYFLAFVGQEWMMDHIVTVYLVLLSLLVMLIVSRLEEKFKKG"
     gene            22374..23024
                     /locus_tag="VQ543_000223"
     CDS             22374..23024
                     /locus_tag="VQ543_000223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000763094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HET2611022.1"
                     /translation="MRLEIINGQKIYGKRPILNQLNLVFQSGKIYGLKGDNGSGKTVL
                     LKILAGYIKLDKGKVLQDGKVYGVKNHYIQDAGILIEKVEFLSHLSLRENLELLRYFS
                     SKVTEKRIAYWIQYYDLQEFEDVEYRHLSLGTKQKMALIQAFISSPSILFLDEPMNAL
                     DEKSVRLTKQVILSYLKKENGLVILTSHISEDISDLCTDVLVVENGHIQYVKDIQS"
     gene            23035..23322
                     /locus_tag="VQ543_000224"
     CDS             23035..23322
                     /locus_tag="VQ543_000224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000940707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2611023.1"
                     /translation="MAHLKSFITRYSKVYIGLVLLIWLSFFFIPWDRAILGVRIDIFI
                     MQKILLAFGILSILMALLSKKVSLFVFGLICCLSLWINLFITFAILPIFGN"
     gene            23468..25981
                     /gene="secA"
                     /locus_tag="VQ543_000225"
     CDS             23468..25981
                     /gene="secA"
                     /locus_tag="VQ543_000225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HET2611024.1"
                     /translation="MANILKTIIENDKGEIRRLEKMADKVFKYEDQMATLTDDQLKAK
                     TVEFKERYQNGESLDSLLYEAFAVVREGAKRVLGLFPYKVQVMGGIVLHHGDVPEMRT
                     GEGKTLTATMPVYLNALSGKGVHVVTVNEYLSERDATEMGELYSWLGLSVGINLATKS
                     PMEKKEAYECDITYSTNSEIGFDYLRDNMVVRAENMVQRPLNYALVDEVDSILIDEAR
                     TPLIVSGANAVETSQLYHMADHYVKSLNKDDYIIDVQSKTIGLSDSGIDRAESYFKLE
                     NLYDIENVALTHFIDNALRANYIMLLDIDYVVSEEQEILIVDQFTGRTMEGRRYSDGL
                     HQAIEAKEGVPIQDETKTSASITYQNLFRMYKKLSGMTGTGKTEEEEFREIYNIRVIP
                     IPTNRPVQRIDHSDLLYASIESKFKAVVEDVKARYQKGQPVLVGTVAVETSDYISKKL
                     VAAGVPHEVLNAKNHYREAQIIMNAGQRGAVTIATNMAGRGTDIKLGEGVRELGGLCV
                     IGTERHESRRIDNQLRGRSGRQGDPGESQFYLSLEDDLMKRFGSERLKGIFERLNMSE
                     EAIESRMLTRQVEAAQKRVEGNNYDTRKQVLQYDDVMREQREIIYAQRYDVITADRDL
                     APEIQAMIKRTIERVVDGHARAKQDEKLEAILNFAKYNLLPEDSITMEDLSGLSDKAI
                     KEELFQRALKVYDSQVSKLRDEEAVKEFQKVLILRVVDNKWTDHIDALDQLRNAVGLR
                     GYAQNNPVVEYQAEGFRMFNDMIGSIEFDVTRLMMKAQIHEQERPQAERHISTTATRN
                     IAAHQASMPEDLDLSQIGRNELCPCGSGKKFKNCHGKRQ"
     gene            26062..27093
                     /locus_tag="VQ543_000226"
     CDS             26062..27093
                     /locus_tag="VQ543_000226"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000232189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HET2611025.1"
                     /translation="MVFTAKSSKINIEEVRALSKLEGQALERKSQRDQELEAIIRGED
                     QRILLVIGPCSSDNEEAVLEYAKRLAVLQEEVADRIFMVMRVYTAKPRTNGDGYKGLI
                     HQPNATEAPSLINGIKAVRHLHYRVITETGMTTADEMLYPENLPLVDDLISYMAVGAR
                     SVEDQQHRFVASGAGFSTGFKNPTSGNLNVMFNGIYAAQNKQSFLFLGKEVETTGNPL
                     SHAILRGALNEYGKNIPNYYYDNLIDTIAQYEKMGLENPFIIIDTNHDNSGKQYIEQI
                     RIVRQTLINRAWNEKIKQFVRGFMIESYLEDGRQNEPEVFGKSITDPCLGWDNTEALV
                     REIYKTLGE"
     gene            27095..28126
                     /locus_tag="VQ543_000227"
     CDS             27095..28126
                     /locus_tag="VQ543_000227"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HET2611026.1"
                     /translation="MAFIEKGQEIDMEVIKAETQLSAEALRLKESRDRELADIISGED
                     DRILLVIGPCSSDNEEAVLEYARRLSALQKKVADKIFMVMRVYTAKPRTNGDGYKGLV
                     HQPDTSKAPSLINGLQAVRQLHYRVITETGLTTADEMLYPSNLILVDDLVSYHAVGAR
                     SVEDQEHRFVASGIDAPVGMKNPTSGNLGVMFNAIYAAQNKQTFLYHGQEVETSGNPL
                     AHVILRGAVNEYGNYMPNYYYENLLQAIERYETMGLENPFILIDTNHDNSGKQYMEQI
                     RIVRQTLQNRDWNEKIKKTVRGFMIESYLADGRQNQPEIFGCSITDPCLGWENTEALV
                     EEIYVTLTK"
     gene            28165..28533
                     /locus_tag="VQ543_000228"
     CDS             28165..28533
                     /locus_tag="VQ543_000228"
                     /EC_number="2.7.8.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000061844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="holo-ACP synthase"
                     /protein_id="HET2611027.1"
                     /translation="MRMIVGHGIDIEELASIESAVTRHEGFAKRVLTAQEMERFTSLK
                     GRRQIEYLAGRWSAKEAFSKAMGTGISKLGFQDLEVLNNERGAPYFSQAPFSGKIWLS
                     ISHTDQFVTASVILEENHES"
     gene            28523..29626
                     /locus_tag="VQ543_000229"
     CDS             28523..29626
                     /locus_tag="VQ543_000229"
                     /EC_number="5.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000648075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HET2611028.1"
                     /translation="MKASPHRPTKALIHLGAIRQNIQQMGAHIPQGTLKLAVVKANAY
                     GHGAVAVAKAIQDDVDGFCVSNIDEAIELRQAGLSKPILILGVSEIEAVALAKEYDFT
                     LTVAGLEWIQALLDKEVDLTGLTVHLKIDSGMGRIGFREASEVEQAQDLLQQHGVRVE
                     GIFTHFATADEESDDYFNAQLERFKTILASMKEVPELVHASNSATTLWHVETIFNAVR
                     MGDAMYGLNPSGAVLALPYDLIPALTLESALVHIKTVPAGACMGYGATYQTDSEQVIA
                     TVPIGYADGWTRDMQNFSVLVDGQACPIVGRVSMDQITIRLPKPYPLGTKVTLIGSNG
                     DKEITATQVATYRVTINYEVVCLLSDRIPREYY"
     gene            29645..31660
                     /gene="recG"
                     /locus_tag="VQ543_000230"
     CDS             29645..31660
                     /gene="recG"
                     /locus_tag="VQ543_000230"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001048793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecG"
                     /protein_id="HET2611029.1"
                     /translation="MNLHQPLHVLPGVGPKSAEKYAKLGIENLQDLLLYFPFRYEDFK
                     IKQVLELEDGEKAVLSGQVVTPASVQYYGFKRNRLRFSLKQGEVVFAVNFFNQPYLAD
                     KIELGATLAVFGKWDRAKASLTGMKVLAQVEDDLQPVYRLAQGISQASLVKVIKTAFD
                     QGLDLLIEENLPQSLLDKYKLMSRCQAVRAMHFPKDLAEYKQALRRIKFEELFYFQMQ
                     LQMLKSENRVQGSGLVLNWSQEKVTAVKVSLPFALTQAQEKSLQEILTDMKSDHHMNR
                     LLQGDVGSGKTVVAGLAMFAAVTAGYQAALMVPTEILAEQHFESLQNLFPNLKLALLT
                     GSLKAAEKREVLETIAKGEADLIIGTHALIQDGVEYARLGLIIIDEQHRFGVGQRRIL
                     REKGDNPDVLMMTATPIPRTLAITAFGDMDVSIIDQMPAGRKPIVTRWIKHEQLPQVL
                     TWLEGEIQKGSQAYVISPLIEESEALDLKNAIALSEELTTHFAGKAEVALLHGRMKSD
                     EKDQIMQDFKERKTDILVSTTVIEVGVNVPNATVMIIMDADRFGLSQLHQLRGRVGRG
                     DKQSYAVLVANPKTDSGKDRMRIMTETTNGFVLAEEDLKMRGSGEIFGTRQSGLPEFQ
                     VADIIEDFPILEEARKVASYISSIEAWQEDPEWRMIALHLEKKEHLD"
     gene            31976..32956
                     /locus_tag="VQ543_000231"
     CDS             31976..32956
                     /locus_tag="VQ543_000231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetylxylan esterase"
                     /protein_id="HET2611030.1"
                     /translation="MKNPALLEEIKTYRGRDEVPEDFDAFWDGEVKNVSTLPSYHLEE
                     RDFHIPQVKCYELTFEGSKEGKVYARIVLPKSEEKVPLIFHFHGYMGRGWDWADMLGF
                     TVAGYGVVSMDVRGQSGYSQDGLRSPLGNTVKGHIIRGAMEGRDHLFYKDVYLDIYQL
                     VEIVASLSQVDEKRLSSYGASQGGALALVAAALNPRIQKTVAIYPFLSDFRRVIEIGN
                     TSEAYDELFRYFKFHDPFHETEEEIMATLAYIDVKNLAHRIQGEVKMITGLDDDVCYP
                     ITQFAIYNRLTCDKTYRIMPEYAHEAMNVFVNDQVYNWLCGSEIPFKYLK"
     gene            33761..33988
                     /locus_tag="VQ543_000232"
     CDS             33761..33988
                     /locus_tag="VQ543_000232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000576349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2611031.1"
                     /translation="MIFKAFKTKKQRKRQVELLLTVFFDSFLIDLFLHLFGIVPFKLD
                     KILIVSLIIFPIISTSIYAYEKLFEKVFDKD"
     gene            34276..37173
                     /gene="nanA"
                     /locus_tag="VQ543_000233"
     CDS             34276..37173
                     /gene="nanA"
                     /locus_tag="VQ543_000233"
                     /EC_number="3.2.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014632427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored neuraminidase NanA"
                     /protein_id="HET2611032.1"
                     /translation="MNRSVQERKCRYSIRKLSVGAVSMIVGAVVFGTSPVLAQEGASE
                     QPLANETQLSGESSTLTDTEKSQPSSETELSGNKQEQERKDKQEEKIPRDYYARDLEN
                     VETVIEKEDVETNASNGQRVDLSSELDKLKKLENATVHMEFKPDAKAPAFYNLFSVSS
                     ATKKDEYFTMAVYNNTATLEGRGSDGKQFYNNYNDAPLKVKPGQWNSVTFTVEKPTAE
                     LPNGRVRLYVNGVLSRTSLKSGNFIKDMPDVTHVQIGATKRANNTVWGSNLQIRNLTV
                     YNRALTPEEVQKRSQLFKRSDLEKKLPEGAALTEKTDIFESGRNGKPNKDGIKSYRIP
                     ALLKTDKGTLIAGADERRLHSSDWGDIGMVIRRSEDNGKTWGNRVTITNLRDNPKASD
                     PSIGSPVNIDMVLVQDPETKRIFSIYDMFPEGKGIFGMSSQKEEAYKKIDGKTYQILY
                     REGEKGAYTIRENGTVYTPDGKATDYRVVVDPVKPAYSDKGDLYKGNQLLGNIYFTTN
                     KTSPFRIAKDSYLWMSYSDDDGKTWSAPQDITPMVKADWMKFLGVGPGTGIVLRNGPH
                     KGRILIPVYTTNNVSHLNGSQSSRVIYSDDHGKTWHAGEAVNDNRQVDGQKIHSSTMN
                     NRRAQNTESTVVQLNNGDVKLFMRGLTGDLQVATSKDGGVTWEKDIKRYPQVKDVYVQ
                     MSAIHTMHNGKEYIILSNAGGPNRENGMVHLARVEENGELTWLKHNPIQKGEFAYNSL
                     QELGNGEYGILYEHTEKGQNAYTLSFRKFNWEFLSKDLISPTEAKVKRTREMGKGEMG
                     KGVIGLEFDSEVLVNKAPTLQLANGKTATFLTQYDSKTLLFAVDKEDIGQEIIGIAKG
                     SIESMHNLPVNLAGARVPGGVNGSKAAVHEVPEFTGGVNGTEPAVHEIAEYKGSDSLV
                     TLTTKEDYTYKAPLAQQALPETGNKESDLLASLGLTAFFLGLFTLGKKREQ"
     gene            38188..38640
                     /locus_tag="VQ543_000234"
     CDS             38188..38640
                     /locus_tag="VQ543_000234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000587452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HET2611033.1"
                     /translation="MIITKISHLGTYVGVNPHFATLIDFLEKTGLENLTEGSIAIDGN
                     RLFGNCFTYLADGQAGAFFETHQKYLDIHLVLENEEAMAVTSPENVSVTQEYDEEKDI
                     ELYTGKVEQLVQLRAGECLITFPEDLHQPKVRINDEPVKKVVFKVAIS"
     gene            38659..39996
                     /locus_tag="VQ543_000235"
     CDS             38659..39996
                     /locus_tag="VQ543_000235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HET2611034.1"
                     /translation="MKKMRKFLCLAGIALAAVALVACSGKKEATTSTEPPTELSGEIT
                     MWHSFTQGPRLESIQKSADAFMQKHPKTKIKIETFSWNDFYTKWTTGLANGNVPDIST
                     ALPNQVMEMVNSDALVPLNDSIKRIGQDKFNETALNEAKIGDDYYSVPLYSHAQVMWV
                     RTDLLKEHNIEVPKTWDQLYEASKKLKEAGVYGLSVPFGTNDLMATRFLNFYVRSGGG
                     SLLTKDLKADLTSQLAQDGIKYWVKLYKEISPQDSLNFNVLQQATLFYQGKTAFDFNS
                     GFHIGGINANSPQLIDSIDAYPIPKIKESDKDQGIETSNIPMVVWKNSKHPEVAKAFL
                     EALYNEEDYVKFLDSTPVGMLPTIKGISDSAAYKENETRKKFKHAEEVITEAVKKGTA
                     IGYENGPSVQAGMLTNQHIIEQMFQDIITNGTDPMKAAKEAEKQLNDLFEAVQ"
     gene            40075..40959
                     /locus_tag="VQ543_000236"
     CDS             40075..40959
                     /locus_tag="VQ543_000236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HET2611035.1"
                     /translation="MVKERNLTRWIFVLPAMIIVGLLFVYPFFSSIFYSFTNKHLIMP
                     NYKFVGLANYKAVLSDPNFFNAFFNSIKWTVFSLVGQVLVGFVLALALHRVRHFKKLY
                     RTLLIVPWAFPTIVIAFSWQWILNGVYGYLPNLIVKLGLMEHTPAFLTDSTWAFLCLV
                     FINIWFGAPMIMVNVLSALQTVPEEQFEAAKIDGASSWQVFKFIVFPHIKVVVGLLVV
                     LRTVWIFNNFDIIYLITGGGPANATTTLPIFAYNLGWGTKLLGRASAVTVLLFIFLVA
                     ICFIYFAIISKWEKEGRK"
     gene            40959..41792
                     /locus_tag="VQ543_000237"
     CDS             40959..41792
                     /locus_tag="VQ543_000237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HET2611036.1"
                     /translation="MKKKSSIYLDILSHVLLVGATIVAIFPLVWIIISSVKGKGELTQ
                     YPTRFWPEQFTLDYFTHVINDLHFIDNIRNSLIIALATTLIAIIISAMAAYGIVRFFP
                     KLGAIMSRLLVITYIFPPILLAIPYSIAIAKVGLTNSLFGLMMVYLSFSVPYAVWLLV
                     GFFQTVPIGIEEAARIDGANKFVTFYKVVLPIVAPGIVATAIYTFINAWNEFLYALIL
                     INNTGKMTVAVALRSLNGSEILDWGDMMAASVIVVLPSIIFFSIIQNKIASGLSEGSV
                     K"
     gene            41810..43903
                     /gene="nanB"
                     /locus_tag="VQ543_000238"
     CDS             41810..43903
                     /gene="nanB"
                     /locus_tag="VQ543_000238"
                     /EC_number="3.2.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="neuraminidase NanB"
                     /protein_id="HET2611037.1"
                     /translation="MNKRGLYSKLGISVVGISLLMGVPTLIHANELNYGQLSISPIFQ
                     GGSYQLNNKSIDISPLLLDKLSGESQTVVMKFKADEPNSLQALFGLSNSKAGFKNNYF
                     SIFMRDSGEIGVEIRDAQKGINYLFSRPASLWGKHKGQAVENTLVFVSDSKDKTYTMY
                     VNGIEVFSETVDTFLPISNINGIDKATLGAVNREGKEHYLAKRSIDEISLFNKAISDQ
                     EVSNIPLSNPFQLIFQSGDSTQANYFRIPTLYTLSSGRVLSSIDARYGGTHDSKSKIN
                     IATSYSDDNGKTWSEPIFAMKFNDYEEQLVYWPRDNKLKNSQISGSASFIDSSIVEDK
                     KSGKTILLADVMPAGIGNNNANKADSGFKEINGHYYLKLKKNGDNDFRYTVRENGVVY
                     DETTNKPTNYTINDKYEVLEGGKSLTVEQYSVDFDSGSLRERHNGKQVPMNVFYKDSL
                     FKVTPTNYIAMTTSQNREESWEQFKLLPPFLGEKHNGTYLCPGQGLALKSSNRLIFAT
                     YTSGELTYLISDDSGQTWKKSSASIPFKNATAEAQMVELRDGVIRTFFRTTTGKIAYM
                     TSRDSGETWSEVSYIDGIQQTSYGTQVSAIKYSQLIDGKEAVILSTPNSRSGRKGGQL
                     VVGLVNKEDDSIDWKYHYDIDLPSYGYAYSAITELPNHHIGVLFEKYDSWSRNELHLS
                     NVVQYIDLEINDLTK"
     gene            43915..45018
                     /locus_tag="VQ543_000239"
     CDS             43915..45018
                     /locus_tag="VQ543_000239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HET2611038.1"
                     /translation="MVKYGVVGAGYFGAELARYMQKNDGAEITLLYDPDNAEAIAEEL
                     GAKVASSLDELVSSDEVDCVIVATPNNLHKEPVIKAAQHGKNVFCEKPIALSYQDCRE
                     MVDACKENNVTFMAGHIMNFFNGVHHAKELINQGVIGDVLYCHTARNGWEEQQPSVSW
                     KKIREKSGGHLYHHIHELDCVQFLMGGMPETVTMTGGNVAHEGEHFGDEDDMIFVNME
                     FSNKRFALLEWGSAYRWGEHYVLIQGSKGAIRLDLFNCKGTLKLDGQESYFLIHESQE
                     EDDDRTRIYHSTEMDGAIAYGKPGKRTPLWLSSVIDKEMRYLHEIMEGAPVSEEFAKL
                     LTGEAALEAIATADACTQSMFEDRKVKLSEIVK"
     gene            45192..45890
                     /locus_tag="VQ543_000240"
     CDS             45192..45890
                     /locus_tag="VQ543_000240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HET2611039.1"
                     /translation="MPQISKEALIEQIKDGIIVSCQALPHEPLYTEAGGVIPLLVKAA
                     EQGGAVGIRANSVRDIKEIKEVTKLPIIGIIKRDYPPQEPFITATMKEVDELAELDIE
                     VIALDCTKRERYDGLEIQEFIRQVKEKYPNQLLMADTSIFEEGLAAVEAGIDFVGTTL
                     SGYTSYSPKVDGPDFELIKKLCDAGVDVIAEGKIHTPEQAKQILEYGVRGIVVGGAIT
                     RPKEITERFVASLK"
     gene            45909..47426
                     /locus_tag="VQ543_000241"
     CDS             45909..47426
                     /locus_tag="VQ543_000241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000477452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HET2611040.1"
                     /translation="MFKVLQKVGKAFMLPIAILPAAGLLLGIGGALSNPTTIATYPIL
                     DNSIFQSIFQVMSSAGEVVFSNLSLLLCVGLCIGLAKRDKGTAALAGVTGYLVMTATI
                     KALVKLFMAEGSAIDTGVIGALVVGIVAVYLHNRYNNIQLPSALGFFGGSRFVPIVTS
                     FSSILIGFVFFVIWPPFQQLLVSTGGYISQAGPIGTFLYGFLMRLSGAVGLHHIIYPM
                     FWYTELGGVETVAGQTVVGAQKIFFAQLADLAHSGLFTEGTRFFAGRFSTMMFGLPAA
                     CLAMYHSVPKNRRKKYAGLFLGVALTSFITGITEPIEFMFLFVSPVLYVVHAFLDGVS
                     FFIADVLNISIGNTFSGGVIDFTLFGILQGNAKTNWVLQIPFGLIWSVLYYIIFRWFI
                     TQFNVLTPGRGEEVDSKEISESADSTSNTADYLKQDSLQIIRALGGSNNIEDVDACVT
                     RLRVAVKEVNQVDKALLKQIGAVDVLEVKGGIQAIYGAKAILYKNSINEILGVDD"
     gene            47551..48879
                     /locus_tag="VQ543_000242"
     CDS             47551..48879
                     /locus_tag="VQ543_000242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000672126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter substrate-binding
                     protein"
                     /protein_id="HET2611041.1"
                     /translation="MKFRKLACTVLAGAAVLGLAACGNSGGSKDAAKSGGDGAKTEIT
                     WWAFPVFTQEKTGDGVGTYEKSIIEAFEKANPDIKVKLETIDFKSGPEKITTAIEAGT
                     APDVLFDAPGRIIQYGKNGKLAELNDLFTDEFVKDVNNENIVQASKAGDKAYMYPISS
                     APFYMAMNKKMLEDAGVANLVKEGWTTDDFEKVLKALKDKGYTPGSLFSSGQGGDQGT
                     RAFISNLYSGSVTDEKVSKYTTDDPKFVKGLEKATSWIKDNLINNGSQFDGGADIQNF
                     ANGQTSYTILWAPAQNGIQAKLLEASKVEVVEVPFPSDEGKPALEYLVNGFAVFNNKD
                     DKKVAASKKFIQFIADDKEWGPKDVVRTGAFPVRTSFGKLYEDKRMETISGWTQYYSP
                     YYNTIDGFAEMRTLWFPMLQSVSNGDEKPADALKAFTEKANETIKKAMKQ"
     gene            49131..49997
                     /locus_tag="VQ543_000243"
     CDS             49131..49997
                     /locus_tag="VQ543_000243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001209417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HET2611042.1"
                     /translation="MRETVISYAFLAPVLFFFVIFVLAPMVMGFITSFFNYSMTKFEF
                     VGLDNYIRMFKDPVFTKSLINTVILVIGSVPVVVLFSLFVASQTYHQNVIARSFYRFV
                     FFLPVVTGSVAVTVVWKWIYDPLSGILNFVLKSSHIISQNISWLGDKNWALMAIMIIL
                     LTTSVGQPIILYIAAMGNIDNSLVEAARVDGATEFQVFWKIKWPSLLPTTLYIAIITT
                     INSFQCFALIQLLTSGGPNYSTSTLMYYLYEKAFQLTEYGYANTIGVFLAVMIAIVSF
                     VQFKVLGNDVEY"
     gene            50013..50852
                     /locus_tag="VQ543_000244"
     CDS             50013..50852
                     /locus_tag="VQ543_000244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HET2611043.1"
                     /translation="MQSTEKKPLTAFTVISTIILLLLTVLFIFPFYWILTGAFKSQPD
                     TIVIPPQWFPKMPTMENFQQLMVQNPALQWMWNSVFISLVTMFLVCATSSLAGYVLAK
                     KRFYGQRILFAIFIAAMALPKQVVLVPLVRIVNFMGIHDTLWAVILPLIGWPFGVFLM
                     KQFSENIPTELLESAKIDGCGEIRTFWSVAFPIVKPGFAALAIFTFINTWNDYFMQLV
                     MLTSRNNLTISLGVATMQAEMATNYGLIMAGAALAAVPIVTVFLVFQKSFTQGITMGA
                     VKG"
     gene            51125..51577
                     /locus_tag="VQ543_000245"
     CDS             51125..51577
                     /locus_tag="VQ543_000245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000575445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HET2611044.1"
                     /translation="MIFDDLKNITFYKGIHPNLDKAIDYLYQHRKDSFELGKYEIDGD
                     KVFLVVQENVLNQVENNQFEHHKNYADLHLLIEGHEYSSYGSRIKDEAVAFDEATDIG
                     FVHCHEHYPLLLGYHNFAIFFPGEPHQPTGYAGMEEKVRKYLFKILID"
     gene            51674..52018
                     /locus_tag="VQ543_000246"
     CDS             51674..52018
                     /locus_tag="VQ543_000246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000254916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2611045.1"
                     /translation="MVSSKHAARASFLDGQEITVDEMSWIINGIVNALIGRYIKLGTY
                     AAKYGIGIARSILSRAAATAAARVGLLTKISGWILRVAVNVADVYGNFANNIAAAWDA
                     YDKIPNNGRINF"
     gene            52028..52219
                     /locus_tag="VQ543_000247"
     CDS             52028..52219
                     /locus_tag="VQ543_000247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2611046.1"
                     /translation="MKALCIFLLNMLAWTVLAMIIRGGLDGFDRHTWSTILIASLFGV
                     YDYKPIDKNRKKSKRKKKK"
     gene            52302..52946
                     /locus_tag="VQ543_000248"
     CDS             52302..52946
                     /locus_tag="VQ543_000248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000057467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HET2611047.1"
                     /translation="MAQKGVSLIKAAFDTDNFLMRFSEKVLDIVTANLLFVVSCLPIV
                     TIGVAKISLYETMFEVKKSRRVPVFKIYLRSFKQNLKLGLQLGLMELGIVFLTLSDLY
                     LFWGQTALPFQLLKAICLGILIFLTIVMLASYPIAARYDLSWKEILQKGLMLASFNFP
                     WFFLMLAILVLIVMVLYLSAFSLLLGGSVFLLFGFGLLVFIQTGLMEKIFAKYQ"
     gene            53115..54032
                     /locus_tag="VQ543_000249"
     CDS             53115..54032
                     /locus_tag="VQ543_000249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrodipicolinate synthase family protein"
                     /protein_id="HET2611048.1"
                     /translation="MSDLKKYEGVIPAFYACYDEQGEVSPERTRALVQYFIDKGVQGL
                     YVNGSSGECIYQSVEDRKLILEEVMAVAKGKLTIIAHVACNNTKDSMELARHAESLGV
                     DAIATIPPIYFRLPEYSVAKYWNDISSAAPNTDYVIYNIPQLAGVALTPSLYTEMLKN
                     PRVIGVKNSSMPVQDIQTFVSLGGEDHIVFNGPDEQFLGGRLMGAKAGIGGTYGAMPE
                     LFLKLNQLIADKDLETARELQYAINAIIGKLTATHGNMYGVIKEVLKINEGLNIGSVR
                     SPLTPVTEEDRPVVEAAAALIRETKESFL"
     gene            54050..54934
                     /locus_tag="VQ543_000250"
     CDS             54050..54934
                     /locus_tag="VQ543_000250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HET2611049.1"
                     /translation="MTYYVAIDIGGTNIKYGLVDQEGQLLESHEMPTEAHKGGPHILQ
                     KTKDIVASYLEKGPVAGVAISSAGMVDPDKGEIFYAGPQIPNYAGTQFKKEIEESFTI
                     PCEIENDVNCAGLAEAVSGSGKGASVTLCLTIGTGIGGCLIMDRKVFHGFSNSACEVG
                     YMHMQDGAFQDLASTTALVKYVAEAHGEDVDQWNGRRIFKEATEGNKICMEGIDRMVD
                     YLGKGLANICYVANPEVVILGGGIMGQEAILKPKIRTALKEALVPSLAEKTRLEFAHH
                     QNTAGMLGAYYHFKTKQS"
     gene            complement(54950..55801)
                     /locus_tag="VQ543_000251"
     CDS             complement(54950..55801)
                     /locus_tag="VQ543_000251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HET2611050.1"
                     /translation="MDKPDIATIIDSHFEEMTDLEQEIARYFLQAETITDDLSSQQVT
                     QKLHISQAALTRFAKKCGFTGYREFIFQYQHQAENQANRVSKHSPLTKRVLRSYSNMR
                     EQTQDLIDEIQLERIAQLIEDAERIYFFGTGSSGLVAREMKLRFMRLGVVCEALTDQD
                     GFAWTTSIMDENCLVLGFSLSGSTPSILDSLLDAKEMGAKTVLFTSVPNKDSQTYTET
                     VLVATHSQPSYIQRISAQLPMLFFIDLIYAYFLEINRESKEKIFNSYWENKKLNGYRR
                     QKRVRKS"
     gene            56001..58058
                     /gene="pbp2b"
                     /locus_tag="VQ543_000252"
     CDS             56001..58058
                     /gene="pbp2b"
                     /locus_tag="VQ543_000252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2B"
                     /protein_id="HET2611051.1"
                     /translation="MRLICMRKFNSHSIPIRLNLLFSIVILLFMTIIGRLLYMQVLNK
                     DFYEKKLASASQTKITSSSARGEIYDASGKPLVENTLKQVVSFTRSNKMTATDLKETA
                     KKLLTYVSISSPNLTKRQLADYYLADPEIYKKTVEALPSEKRLDSDGNRLSESELYNN
                     AVDSVQTSQLNYTEDEKKEIYLFSQLNAVGNFATGTIATDPLNDSQVAVIASISKEMP
                     GISISTSWDRKVLETSLSSIVGSVSSEKAGLPAEEAEAYLKKGYSLNDRVGTSYLEKQ
                     YEETLQGKRSVKEIHLDKYGNMESVDTIEEGSKGNNIKLTIDLAFQDSVDALLKSYFN
                     SELENGGAKYSEGVYAVALNPKTGAVLSMSGIKHDLKTGELTPDSLGTVTNVFVPGSV
                     VKAATISSGWENGVLSGNQTLTDQSIVFQGSAPINSWYTQAYGSFPITAVQALEYSSN
                     TYMVQTALGLMGQTYQPNMFVGTSNLESAMEKLRSTFGEYGLGTATGIDLPDESTGFV
                     PKEYSFANYITNAFGQFDNYTPMQLAQYVATIANNGVRVAPRIVEGIYGNNDKGGLGD
                     LIQQLQPTEINKVNISDSDMSILHQGFYQVAHGTSGLTTGRAFSNGALVSISGKTGTA
                     ESYVADGQQATNTNAVAYAPSDNPQIAVAVVFPHNTNLTNGVGPSIARDIINLYQKYH
                     PMN"
     gene            58069..58665
                     /gene="recR"
                     /locus_tag="VQ543_000253"
     CDS             58069..58665
                     /gene="recR"
                     /locus_tag="VQ543_000253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002896112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination protein RecR"
                     /protein_id="HET2611052.1"
                     /translation="MLYPTPIAKLIDSYSKLPGIGIKTATRLAFYTIGMSADDVNEFA
                     KNLLSAKRELTYCSICGRLTDDDPCSICTDPTRDQTTILVLEDSRDVAAMENIQEYHG
                     LYHVLHGLISPMNGISPDDINLKSLMTRLMDSEVSEVIVATNATADGEATSMYLSRLL
                     KPAGIKVTRLARGLAVGADIEYADEVTLLRAIENRTEL"
     gene            58841..59884
                     /locus_tag="VQ543_000254"
     CDS             58841..59884
                     /locus_tag="VQ543_000254"
                     /EC_number="6.3.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HET2611053.1"
                     /translation="MKQTIILLYGGRSAEREVSVLSAESVMRAVNYDRFTVKTFFISQ
                     SGDFIKTQEFSHAPGQEDRLMTNETIDWDKKVAPSAIYEEGAVVFPVLHGPMGEDGSV
                     QGFLEVLKMPYVGCNILSSSLAMDKITTKRVLESAGIAQVPYVAIVEGDDVTAKIAEV
                     EEKLAYPVFTKPSNMGSSVGISKSENQEELRQALKLAFRYDSRVLVEQGVNAREIEVG
                     LLGNYDVKSTLPGEVVKDVAFYDYDAKYIDNKITMDIPAKISDDVVAVMRQNAETAFR
                     AIGGLGLSRCDFFYTDKGEIFLNELNTMPGFTQWSMYPLLWDNMGISYPELIERLVDL
                     AKESFDKREAHLI"
     gene            59968..61341
                     /locus_tag="VQ543_000255"
     CDS             59968..61341
                     /locus_tag="VQ543_000255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000778684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-
                     alanine ligase"
                     /protein_id="HET2611054.1"
                     /translation="MKLTIHEVAQVVGAKNDISIFEDTQLEKAEFDSRLIGTGDLFVP
                     LKGVRDGHDFIERAFENGAAATLSEKEVANHPYILVDDVLTAFQQLAAYYLEKTAVDV
                     FAVTGSNGKTTTKDMLAHLLSTRYKTYKTQGNYNNEIGLPYTVLHMPEGTEKLVLEMG
                     QDHLGDIHLLSELARPKTAIVTLVGEAHLAFFKDRSEIAKGKMQIADGMASGSLLLAP
                     ADPIVEDYLPTDKKVVRFGQGAELEITDLVERKDSLTFKANFLEQVLDLPVTGKYNAT
                     NAMIASYVALQEGVSEEQIRLAFQHLELTRNRTEWKKAANGADILSDVYNANPTAMKL
                     ILETFSAIPANEGGKKIAVLADMKELGVQSVQLHNQMILSLSPDVLDTVIFYGEDIAE
                     LAQLASQMFPIGHVYYFKKTEDQDQFEDLVKQVKESLGAHDQILLKGSNSMNLAKLVE
                     SLENEDK"
     gene            61328..61939
                     /locus_tag="VQ543_000256"
     CDS             61328..61939
                     /locus_tag="VQ543_000256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HET2611055.1"
                     /translation="MKTSDFVKYLQRMIAITDTGLTFTKDPFDRERYEDLRDLLSEML
                     NQASDLDSEEVAEVLKPTSAYATPLMDVRAWIVEDEKICLVRGQGEDSWALPGGFGEV
                     GYSPTENILKEIEEETGFKAKVERLLAVFDTNRFQLQSKQYAKFVFECKLLDGQFQEN
                     QEIADLQFFAIDPLPNLSEKRITKEQIEILWQVYQGQREQYLD"
     gene            62030..62734
                     /locus_tag="VQ543_000257"
     CDS             62030..62734
                     /locus_tag="VQ543_000257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001055242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR02206 family membrane protein"
                     /protein_id="HET2611056.1"
                     /translation="MNLWDIFFTTQATEPPKFDLFWYVSLFTLLALTFYTAHRYREKK
                     VYQRFFQILQTVQLILLYGWYWVNHMPLSESLPFYHCRMAMFVVLLLPGQSKYKQYFA
                     LLGTFGTLAAFVYPVPDAYPFPHITILSFIFGHLALLGNSLVYLLRQYNARLLDVKGI
                     FLMTFALNALIFVVNLVTGGDYGFLTKPPLVGDHGLVANYLLVSIVLVATISLTKKIL
                     EFFLAQEAEKMIAKEA"
     gene            62953..64326
                     /gene="ftsA"
                     /locus_tag="VQ543_000258"
     CDS             62953..64326
                     /gene="ftsA"
                     /locus_tag="VQ543_000258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000090410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsA"
                     /protein_id="HET2611057.1"
                     /translation="MAREGFFTGLDIGTSSVKVLVAEQRNGELNVIGVSNAKSKGVKD
                     GIIVDIDAAATAIKSAISQAEEKAGISIKSVNVGLPGNLLQVEPTQGMIPVTSDTKEI
                     TDQDVENVVKSALTKSMTPDREVITFIPEEFIVDGFQGIRDPRGMMGVRLEMRGLLYT
                     GPRTILHNLRKTVERAGVQVENIIISPLAMVQSVLNEGEREFGATVIDMGAGQTTVAT
                     IRNQELQFTHILQEGGDYVTKDISKVLKTSRKLAEGLKLNYGEAYPPLASKETFQVEV
                     IGEVEAVEVTEAYLSEIISARIKHILEQIKQELDRRRLLDLPGGIVLIGGNAILPGMV
                     ELAQEVFGVRVKLYVPNQVGIRNPAFAHVISLSEFAGQLTEVNLLAQGAIKGENDLSH
                     QPISFGGMLQKTAQFVQSTPVQPAPAPEVESVAPTEPMADFQQASQNKPKLADRFRGL
                     IGSMFDE"
     gene            64343..65602
                     /gene="ftsZ"
                     /locus_tag="VQ543_000259"
     CDS             64343..65602
                     /gene="ftsZ"
                     /locus_tag="VQ543_000259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000144288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsZ"
                     /protein_id="HET2611058.1"
                     /translation="MTFSFDTAAAQGAVIKVIGVGGGGGNAINRMVDEGVTGVEFIAA
                     NTDVQALSSTKAETVIQLGPKLTRGLGAGGQPEVGRKAAEESEETLTEAISGADMVFI
                     TAGMGGGSGTGAAPVIARIAKDLGALTVGVVTRPFGFEGSKRGQFAVEGINQLREHVD
                     TLLIISNNNLLEIVDKKTPLLEALSEADNVLRQGVQGITDLITNPGLINLDFADVKTV
                     MANKGNALMGIGIGSGEERVVEAARKAIYSPLLETTIDGAEDVIVNVTGGLDLTLIEA
                     EEASQIVNQAAGQGVNIWLGTSIDESMRDEIRVTVVATGVRQDRVEKVVAPQARSATN
                     YRETVKPAHSHGFDRHFDMAETVELPKQNPRRLEPTQASAFGDWDLRRESIVRTTDSV
                     VSPVERFEAPISQDEDELDTPPFFKNR"
     gene            65607..66278
                     /locus_tag="VQ543_000260"
     CDS             65607..66278
                     /locus_tag="VQ543_000260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggS family pyridoxal phosphate-dependent
                     enzyme"
                     /protein_id="HET2611059.1"
                     /translation="MNVKENTELVFREVAEASLSAHRESGSVSVIAVTKYVDVPTAEA
                     LLPLGVHHIGENRVDKFLEKYEALKDRDVTWHLIGTLQRRKVKDVIQYVDYFHALDSV
                     KLAGEIQKRSDRVIKCFLQVNISKEESKHGFSREELLEILPELARLDKIEYVGLMTMA
                     PFEASSEQLKEIFKATQDLQREIQEKQIPNMPMTELSMGMSRDYKEAIQFGSTFVRIG
                     TSFFK"
     gene            66288..66827
                     /locus_tag="VQ543_000261"
     CDS             66288..66827
                     /locus_tag="VQ543_000261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000053379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein SepF"
                     /protein_id="HET2611060.1"
                     /translation="MSLKDRFDRFIDYFTEDEDSSLPYEKRDEPVFTPVNSSQEPALP
                     MNQPSQSAGTKENNITRLHARQQELANQSQRATDKVIIDVRYPRKYEDATEIVDLLAG
                     NESILIDFQYMTEVQARRCLDYLDGACHVLAGNLKKVASTMYLLTPVNVIVNVEDIRL
                     PDEDQQGEFGFDMKRNRVR"
     gene            66827..67090
                     /locus_tag="VQ543_000262"
     CDS             66827..67090
                     /locus_tag="VQ543_000262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000576515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggT family protein"
                     /protein_id="HET2611061.1"
                     /translation="MIFLIRMIYNAVDIYSLILVAFAVMSWFPGAYESSLGRWIVALV
                     KPVLAPLQRLPLQIAGLDLSVWVAIVLVRFLGENLVRFLAMIG"
     gene            67087..67771
                     /locus_tag="VQ543_000263"
                     /pseudo
     CDS             67087..67771
                     /locus_tag="VQ543_000263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398113.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein"
     gene            67780..68568
                     /gene="divIVA"
                     /locus_tag="VQ543_000264"
     CDS             67780..68568
                     /gene="divIVA"
                     /locus_tag="VQ543_000264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein DivIVA"
                     /protein_id="HET2611062.1"
                     /translation="MPITSLEIKDKTFGTRFRGFDPEEVDEFLDIVVRDYEDLVRANH
                     DKNLRIKSLEERLSYFDEIKDSLSQSVLIAQDTAERVKQAAHERSNNIIHQAEQDAQR
                     LLEEAKYKANEILRQATDNAKKVAVETEELKNKSRVFHQRLKSTIESQLAIVESSDWE
                     DILRPTATYLQTSDEAFKEVVSEVLGEPIPAPIEEEPIDMTRQFSQAEMEELQARIEV
                     ADKELSEFEAQIKQEVETPTPVVSPQVEEEPLLIQLAQCMKNQK"
     gene            68916..71708
                     /locus_tag="VQ543_000265"
     CDS             68916..71708
                     /locus_tag="VQ543_000265"
                     /EC_number="6.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoleucine--tRNA ligase"
                     /protein_id="HET2611063.1"
                     /translation="MKLKDTLNLGKTEFPMRAGLPTKEPVWQKEWEDAKLYQRRQELN
                     QGKPHFTLHDGPPYANGNIHVGHAMNKISKDIIVRSKSMSGFYAPFIPGWDTHGLPIE
                     QVLSKQGVKRKEMDLVEYLKLCREYALSQVDKQREDFKRLGVSGDWENPYVTLTPDYE
                     AAQIRVFGEMANKGYIYRGAKPVYWSWSSESALAEAEIEYHDLVSTSLYYANKVKDGK
                     GVLDTDTYIVVWTTTPFTITASRGLTVGADIDYVLVQPAGEARKFVVAAELLTSLSEK
                     FGWADVQVLETYRGQELNHIVTEHPWDTAVEELVILGDHVTTDSGTGIVHTAPGFGED
                     DYNVGIANNLEVAVTVDERGIMMKNAGPEFEGQFYEKVVPTVIEKLGNLLLAQEEISH
                     SYPFDWRTKKPIIWRAVPQWFASVSKFRQEILDEIEKVKFHSEWGKVRLYNMIRDRGD
                     WVISRQRAWGVPLPIFYAEDGTAIMVAETIEHVAQLFEEHGSSIWWERDAKDLLPEGF
                     THPGSPNGEFKKETDIMDVWFDSGSSWNGVVVNRPELTYPADLYLEGSDQYRGWFNSS
                     LITSVANHGVAPYKQILSQGFALDGKGEKMSKSLGNTIAPSDVEKQFGAEILRLWVTS
                     VDSSNDVRISMDILSQVSETYRKIRNTLRFLIANTSDFNPAQDTVAYDELRSVDKYMT
                     IRFNQLVKTIRDAYANFEFLTIYKALVNFINVDLSAFYLDFAKDVVYIEGAKSLERRQ
                     MQTVFYDILVKITKLLTPILPHTAEEIWSYLEFEAEDFVQLSELPEVQTFANQEEILD
                     TWAAFMDFRGQAQKALEEARNAKVIGKSLEAHLTVYPNEVVKTLLEAVNSNVAQLLIV
                     SELTIAEEPAPEAALSFEDVVFTVERAAGEVCDRCRRIDPTTAERSYHAVICDHCASI
                     VEENFADAVAEGFEEK"
     gene            72118..72480
                     /locus_tag="VQ543_000266"
     CDS             72118..72480
                     /locus_tag="VQ543_000266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000842495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2611064.1"
                     /translation="MKSSGIVGLVGGILLLICPFVLLGTAVNTAATTLNGGATAGAFS
                     GVALLLNALKIANLVLGIIAIVYYKGDKHVGAAPSVLMIVSGEVSLIPFLGWVGGILA
                     IIGGSLFLATLKKFKSEE"
     gene            73015..73707
                     /locus_tag="VQ543_000267"
     CDS             73015..73707
                     /locus_tag="VQ543_000267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006703946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate mutase"
                     /protein_id="HET2611065.1"
                     /translation="MVKLVFARHGESEWNKANLFTGWADVDLSEKGTQQAIDAGKLIK
                     EAGIEFDQAYTSVLKRAIKTTNLALEASDQLWVPVEKSWRLNERHYGGLTGKNKAEAA
                     EQFGDEQVHIWRRSYDVLPPNMDRDDEHSAHTDRRYASLDDSVIPDAENLKVTLERAL
                     PFWEDKIAPALKDGKNVFVGAHGNSIRALVKHIKGLSDDEIMDVEIPNFPPLVFEFDE
                     KLNVVSEYYLGK"
     gene            73760..76171
                     /locus_tag="VQ543_000268"
     CDS             73760..76171
                     /locus_tag="VQ543_000268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000620712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 95 protein"
                     /protein_id="HET2611066.1"
                     /translation="MIRNKKQDYVLAYKQPASTTYMGWEEEALPIGNGSLGAKVFGLI
                     GAERIQFNEKSLWSGGPLPDSSDYQGGNLQDQYVFLAEIRQALEKRDYNLAKELAEQH
                     LIGPKTSQYGTYLSFGDIHIEFSQQGTTLSQVTDYQRQLNISKALATTSYVYKGTRFE
                     RKAFASFPDDLLIQCFTKEGLETLDFTIELSLTCDLASDGKYEQEKSDYKECKLDITD
                     SHILMKGRVKDNDLRFASYLAWETDGDIRVWSDRVQISGASYANLFLAAKTDFAQNPA
                     SNYRKKLDLEQQVIDLVDTAKEKGYTQLKSRHIEDYQALFQRVQLDLEADVDASTTDD
                     LLKNYKPQEGQALEELFFQYGRYLLISSSRDCPDALPANLQGVWNAVDNPPWNSDYHL
                     NVNLQMNYWPAYVTNLLETVFPVINYVDDLRVYGRLAAVKYAGIVSQKGEENGWLVHT
                     QATPFGWTAPGWDYYWGWSPAANAWMMQTVYEAYSFYRDQDYLREKIYPMLRETVRFW
                     NAFLHKDQQAQRWVSSPSYSPEHGPISIGNTYDQSLIWQLFHDFIQAAQELGLDEDLL
                     TEVKEKSDLLNPLQITQSGRIREWYEEEEQYFQNEKVEAQHRHASHLVGLYSGNLFSY
                     KGQEYIEAARAILNDRGDGGTGWSKANKINLWARLGDGNRAHKLLAEQLKTSTLPNLW
                     CSHPPFQIDGNFGATSGMAEMLLQSHAAYLVPLAALPDAWSTGSVSGLMARGHFEVSM
                     SWEDKKLLQLTILSRSGGDLRVSYPDIEKSVIKMNQEKIKAKCMGKDCISVATAEGDL
                     VQFYF"
     gene            76421..77122
                     /locus_tag="VQ543_000269"
     CDS             76421..77122
                     /locus_tag="VQ543_000269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2611067.1"
                     /translation="MAYIEMKHCYKRYQVGDTEIVANRDVNFEIEKGELVIILGASGA
                     GKSTVLNLLGGMDTNDEGEIWIDGVNIADYSSHQRTNYRRNDVGFVFQFYNLVSNLTA
                     KENVELASEIVTDALNPDQVLTDVGLAHRLNNFPAQLSGGEQQRVSIARAVAKNPKIL
                     LCDEPTGALDYQTGKQVLKILQDMSRQKGATVIIVTHNGALAPIADRVIQMHDASVKD
                     VVLNQHPQDIDSLEY"
     gene            77124..79824
                     /locus_tag="VQ543_000270"
                     /pseudo
     CDS             77124..79824
                     /locus_tag="VQ543_000270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000595876.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
     gene            complement(79920..80411)
                     /gene="tpx"
                     /locus_tag="VQ543_000271"
     CDS             complement(79920..80411)
                     /gene="tpx"
                     /locus_tag="VQ543_000271"
                     /EC_number="1.11.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol peroxidase"
                     /protein_id="HET2611068.1"
                     /translation="MVTFLGNPVSFTGKQLQVGDKALDFSLTTTDLSKKSLADFDGKK
                     KVLSVVPSIDTGICSTQTRRFNEELAGLDNTVVLTVSMDLPFAQKRWCGAEGLDNAIM
                     LSDYFDHSFGRDYALLINEWHLLARAVFVLDTDNTIRYVEYVDNINSEPNFEAAIAAA
                     KAL"
     gene            complement(80534..81463)
                     /gene="psaA"
                     /locus_tag="VQ543_000272"
     CDS             complement(80534..81463)
                     /gene="psaA"
                     /locus_tag="VQ543_000272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000733059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding
                     lipoprotein/adhesin PsaA"
                     /protein_id="HET2611069.1"
                     /translation="MKKLGTLLVLFLSAIILVACASGKKDTTSGQKLKVVATNSIIAD
                     ITKNIAGDKIDLHSIVPIGQDPHEYEPLPEDVKKTSEADLIFYNGINLETGGNAWFTK
                     LVENAKKTENKDYFAVSDGVDVIYLEGQNEKGKEDPHAWLNLENGIIFAKNIAKQLSA
                     KDPNNKEFYEKNLKEYTDKLDKLDKESKDKFNKIPAEKKLIVTSEGAFKYFSKAYGVP
                     SAYIWEINTEEEGTPEQIKTLVEKLRQTKVPSLFVESSVDDRPMKTVSQDTNIPIYAQ
                     IFTDSIAEQGKEGDSYYSMMKYNLDKIAEGLAK"
     gene            complement(81495..82343)
                     /locus_tag="VQ543_000273"
     CDS             complement(81495..82343)
                     /locus_tag="VQ543_000273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000559784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HET2611070.1"
                     /translation="MIAEFIDGLQKFHFLQNALITAIVVGIVAGAVGCFIILRGMSLM
                     GDAISHAVLPGVALSFILGLDFFIGAIVFGLLAAIIITYIKGNSIIKSDTAIGITFSS
                     FLALGIILIGVAKSSTDLFHILFGNILAVQDTDMFITMGVGAAILLLIWIFFKQLLIT
                     SFDELLAKAMGMPVNFYHYLLMVLLTLVSVTAMQSVGTILIVAMLITPAATAYLYANS
                     LKSMIFLSSTFGATASVLGLFIGYSFNVAAGSSIVLTAASFFLISFFIAPKQRYLKLK
                     NKHLLK"
     gene            complement(82340..83062)
                     /locus_tag="VQ543_000274"
     CDS             complement(82340..83062)
                     /locus_tag="VQ543_000274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HET2611071.1"
                     /translation="MIRIENLSVSYKETLALKDISLVLHGPTITGIIGPNGAGKSTLL
                     KGMLGIIPHQGQAFLDDKEVKKSLHRIAYVEQKINIDYNFPIKVKECVSLGLFPSIPL
                     FRSLKAKHWKKVQEALEIVGLADYAERQISQLSGGQFQRVLIARCLVQEADYILLDEP
                     FAGIDSVSEEIIMNTLRDLKKAGKTVLIVHHDLSKIPHYFDQVLLVNREVIAFGPTKE
                     TFTETNLKEAYGNQLFFNGGDL"
BASE COUNT        25138 a        15160 c        18365 g        24493 t
ORIGIN      
        1 tactttcctt attgtctgta aatctactga ccttgttgtt tatcccagtc atggtttcta
       61 gttcgggctc agagtttcaa agtggatggc aagagcatca attgattgct gagaaggtta
      121 gtaaaacact tgataagaca tttgataagg atgtcagaga aattccgacc agtcagtttt
      181 atcaaaaatt tgtagatgag atgggaagga tttactcagg aaatttgatc ctccaggagc
      241 tgataactgt gaatggagct tataaagcta cttatatcgg tgaactctct agcaactaat
      301 cattctttaa aatgatgacc aataagaggc ttgatttggt gaatcaagtc ttttttctct
      361 cttttactgc catttgtgat aaaatagtat agaacgattt tttacatgaa tgataaaaca
      421 gaggtaaata tgacaatcgg tattgataag attggttttg cgaccagtca atatgtcttg
      481 aaattacaag acttagcaga agcgagggga attgaccctg aaaaattaag taaaggactc
      541 ttactcaagg aattgagtat tgcgccccta actgaggaca tcgtgacctt ggcggccagt
      601 gctagtgact ctattttaac tgagcaagaa agacaagaag ttgacatggt cattgtggct
      661 accgagtcag gaattgacca gagtaaggct gcggccgtct ttgtgcatgg cttgctgggc
      721 atccagccct ttgctcgtag tttcgagatt aaagaagcct gctatggggc gacagctgcc
      781 ctccattatg ccaaattgca tgtggaaaat tctccggagt ccaaggtctt ggtcattgcc
      841 agtgatattg ccaaatatgg tattgaaact ccgggagaac caactcaagg tgctggaagt
      901 gtagctatgt tgattacaca aaatccacgc atgatggcct ttaataatga caatgtagct
      961 cagacccgtg acatcatgga tttctggcga ccaaattact cgacaactcc ttatgtaaat
     1021 ggtgtctatt ctacccaaca atacttggat agtttgaaaa cgacttggct tgaatatcaa
     1081 aaacgctacc agcttactct ggatgatttt gcggctgttt gtttccactt gccttatcct
     1141 aaattagcgc taaaaggctt gaaaaaaatc atggataaga gcctgcctca agagaaaaaa
     1201 gacctcttac aaaagcattt tgaccagtct attctctaca gtcaaaaggt ggggaatatc
     1261 tacacaggtt cacttttcct tggacttttg tctctcttgg aaaatgcaga tagcttgaaa
     1321 gctggggata aaatcgccct ttatagttac ggaagtggag ctgtggctga gttcttcagt
     1381 ggtgaattgg ttgaaggata tgaagcttat ttggataaag accgcttgaa caagctcaac
     1441 caacgaactg ccttatccgt tgcagactat gaaaaggtct tttttgagga agtaaacttg
     1501 gatgaaacaa actctgccca gtttgctggc tatgaaaatc aagattttgc cttggttgaa
     1561 attctcgacc accaacgccg ttatagcaag gttgaaaaat aatgaagata agttggaatg
     1621 gattttctaa aaaatcatac caagagcgcc tcgagctgtt aaaagctcag gcgctcctta
     1681 gtcctgagag acaagctagt ctggagaagg atgaacagat gagtgtgact gtggcagacc
     1741 agctgagtga gaatgtagtg ggaacttttt ctctgcctta ttcgctggtt ccggaggtac
     1801 ttgtcaacgg tcaggaatac accgttccct atgtgacaga agaaccctct gtggttgcgg
     1861 cggccagcta tgccagcaaa atcatcaagc gtgcaggtgg ttttactgca caagtccatc
     1921 agcgccagat gattgggcag gtagcccttt atcaagttgc taatcctaaa ctagcgcaag
     1981 agaagattgc cagcaagaaa gcggagctct tggagtttgc caatcaagcc tatccttcta
     2041 tcgttaaacg tggaggtggg gcgcgtgatc tgcatgtcga gcagataaaa ggcgaaccag
     2101 actttctcgt tgtttatatt catgtcgata cccaggaagc catgggtgcc aatatgctca
     2161 acaccatgct ggaagccttg aaaccagtct tagaagaact cagtcaggga cagagtctca
     2221 taggaatcct gtccaactac gcgaccgatt ctctggtgac tgcaagctgt cgcatggcct
     2281 ttcgctactt gagccgccaa aaggatcaag gacgagagat tgcggagaaa attgcgttgg
     2341 ctagtcagtt tgcgcaggct gatccttacc gagctgctac tcataataaa ggaattttta
     2401 atggtattga tgcgattttg attgccactg gtaatgactg gcgtgccatc gaagctgggg
     2461 cccatgcctt tgccagtcga gatggacgct atcaaggtct tagttgctgg acgctggacc
     2521 ttgaaagaga agaattggtc ggtgagatga ccctgcccat gcctgtagcg actaagggtg
     2581 gctctatcgg cctcaaccca cgtgtagctt tcagtcatga tctactagga aatccttctg
     2641 ccagagaatt agcccagatt atcgtgtcca tcggtcttgc ccaaaatttt gcagccctca
     2701 aagctttggt aagtacgggc atccagcaag gccacatgaa actacaggcc aaatccctag
     2761 ctctcctagc tggggctagt gaatctgaag ttgctcccct agtagagcgc ctcatctcag
     2821 ataaaacctt taacctagag acagcccagc gctatctcga aaatttaaga tcataaaaaa
     2881 ctcagacgaa tcggtctgag ttttcttgtg tttaaatact ttttcctggt aatagtgtaa
     2941 ctggtaagaa gtaaccagtt gtggcaactt ccttgccttc aatcttttgc aagagaagat
     3001 caatagtgag acaagcaatc tcttccaaag gttgcttgat agtagccaat tgagggtagt
     3061 aattttcgat aaagtaggtc ccatcatagc cgatgacctt gagctctttt gggacagaaa
     3121 tgcccaattc ttgagcgatt ttaatgacca gaatagctgt caaatcatcc gaagcaaaaa
     3181 tggcatctgg tttttcccgg gtcaagatat tcttgatttc catttctttt ctgacgggag
     3241 aaaagtcact ggaaacattg ataataggag cttttgggag tacggatgca aaaccagcgt
     3301 ggcgtagtcc ggttggcgaa ttggaattgt cattccctgt aatcatgatg atagtctggg
     3361 cacctgtctt gaccaaggtt tgggcagcaa gaaccccacc agcatagttg tcagaggaga
     3421 cgacagggat gtctggcgat aggtttcggt caaaggaaat aatcggcgct gtcacacgat
     3481 tgtagtcttc gattcctagg ttgtgactac cagaaatgat gccgtccacc tgattggctt
     3541 ccaacatttc gatgtattcg cgttccttct cagaatcatg ttcactgttg cagatgatgg
     3601 tcttgtaacc atttttgaag agttggtgtt ccaatttatc aatcaattct gcatagaaaa
     3661 cattggaaat attagggaaa atcaagccga ttaacttagc tgattttcct tgcagactac
     3721 gagccaggtt gttgggttta tagcccaatt ctcgcatggc ttcattgact ttttggatgg
     3781 ttttctcaga tagataccct tttttattga taacccgaga aacggtagta ggactgacgc
     3841 ctgcaagttt ggcgacatca gttagttttg cgaccataat ctaattcata gtaagttcca
     3901 gttgggtttc cagatttgat caggatacca ttttggtccg catgtgggaa gacacgacca
     3961 gaaaatactt tttctccttt attgatgaaa atttcaaaga cagagttatc gatgaagatt
     4021 gtagcagtag tagcctgatt ctcgataggg caagaacgag ttgtcccaaa ttcttgggca
     4081 tactgttctc cagcctggct acgatccact gtcacttgac cgtttacaag gtcaaagttg
     4141 attgaaagtc ccttaccttc tttatcagca agtaagacaa tctcgctctg gctattagct
     4201 tccaagttga gttcaagttc gtaagtgttc ttggtttggg aacggtttga gaaggcttct
     4261 tcagaagcac gaaggtcctt aatagcagcg actggatact ggtagagctt gtcgtctttg
     4321 atagtgagtt ccttgaccaa agagaaggtt ccttggtggt caaaacggtc agatgggtaa
     4381 gaaacatctg gcaaaccaag ccagctaact gctagagcac gcccatcagg agcgttgaag
     4441 gcttgagttg cataggcttc gaaaccgtaa tccatgtttt gaagttgaga cacatctacc
     4501 attttggcat ttttagggtc aaaggaagcc ccaatcttat acatatttgg aaagatatta
     4561 tcgtagtcta gaactttctt atccaatcct tgtggacagt agagaaggac aggatgttcc
     4621 tctacaaaga ccagattagg acattccatc atgtaggcag tacggtcgtt agcaaagtca
     4681 aggtcgccaa ctgcttgcca gtttgtgtag tcgttattga cagccttgta gagacggacg
     4741 aagccttttt tctccaagtc ctgtccaccg acgacagcat agtattgact tttaaagtta
     4801 aaaatttgtg gatcgcggaa gtggtcagta gagtctgctg gctggtcaat caagatcttg
     4861 tcaatctttg taatcttacc ctccttgtcc atcaaagcac cgatctggta tgggtgacgg
     4921 atccagtttt catcgcgaac atttcctgta taaaatagga ataagttatc gccaaattgc
     4981 atggcagaac cagagtaggc accgtggcta tctaatggag tatctggtaa aactttgatt
     5041 ccagtttctt taaagtgaac caaatcatca ctttctagct gtgcccaaga tttcaaaccg
     5101 tgggctgcac caaaaggaaa attctggtaa aagaggatcc acttgccatc aaagtaagaa
     5161 aagccatttg ggtcgttgag aagtcctgtt tttggctcaa catggtaatg agtatgccat
     5221 ggagattgtg ccatattttc ctttatatgt tgaatttctt cttgcgtcca atcttgataa
     5281 agtctgtaac gacgctcagt tgtccattcc attcattcct ccaaaaatct tatcactttt
     5341 aatagtaact gttttcgata aaaaatgcaa gccttttatg ttaaaaaaga ggaaaaactg
     5401 tcaaacgatt atcataaaat aaatacagga aatcaatcaa atttttacga aaatgtgaaa
     5461 gataatgaaa taaaagactt tttaaccaag gtttcaaact tatttttcaa ggaattcctg
     5521 atgaaacagt caaaaacaat caatctaaaa cttgcccact aagtggatag aatatttttt
     5581 ctgcaaaacg cttgacatat ttttaaaaca tgataaaata atagtcgtaa gggcgaataa
     5641 aatcgctttc aaacaagaac aaaatgttat ataaggagat ttttgcaaat gaacaatcag
     5701 gaaattgcaa aaaaagtcat cgatgccttg ggcggacgtg aaaatgtcaa tagtgttgcc
     5761 cactgtgcga ctcgtctacg tgtcatggtc aaagatgaag agaaaatcaa taaagaagtg
     5821 attgagaact tggaaaaagt tcaaggtgct ttctttaact cagggcaata ccaaattatc
     5881 tttggtacag gtacagttaa caaaatgtac gatgaagttg ttgtacttgg cttaccaaca
     5941 tcatctaagg atgacatgaa agcagaagtt gctaaacaag ggaactggtt ccaacgtgct
     6001 atccgtactt tcggtgatgt tttcgttcca atcatcccag ttatcgtagc gacaggtctc
     6061 ttcatgggtg tgcgtggtct tttcaacgct cttgaaatgc cacttccagg tgactttgca
     6121 acttacacac aaatcttgac agatacagcc ttcatcatct tgccaggttt ggttgtgtgg
     6181 tcaaccttcc gtgtatttgg tggaaatcct gccgttggta tcgttcttgg tatgatgctt
     6241 gtctctggct cacttccaaa cgcttgggca gttgctcaag gtggtgaagt aacagcgatg
     6301 aacttctttg gtttcatccc tgttgttggt ttgcaaggtt ccgttcttcc agccttcatc
     6361 atcggggttg tcggagctaa atttgaaaaa gctgtccgca aggttgttcc agatgtcatt
     6421 gacctcttgg taacaccatt cgtgacactt ttggtcatgt ctatccttgg actctttgtc
     6481 attggaccag ttttccacgt tgttgaaaac tacatcctta ttgctacaaa agcgattctt
     6541 agcatgccat ttggtcttgg tggtttcttg attggtgggg ttcaccaatt gatcgtcgtg
     6601 tcaggtgtgc accacatctt caacttgctt gaagtgcaat tacttgctgc tgaccatgct
     6661 aacccattca acgctatcat cacagctgct atgacagctc aaggtgctgc tactgttgcg
     6721 gttggtgtta aaacaaaaaa tccaaaactg aaaacacttg ctttcccggc tgctctttct
     6781 gccttcctag gtattacaga gcctgctatc ttcggggtga acttgcgctt ccgtaaacca
     6841 ttcttccttt cattgattgc tggtgcaatc ggtggtggat tggcttctat ccttggactt
     6901 gctggtactg gtaatggtat caccatcatc cctggtacaa tgctttatgt tggtaacgga
     6961 caacttccac aataccttct tatggtagct gtatcatttg cccttggttt tgctcttact
     7021 tacatgtttg gttacgaaga tgaagtagac gcaactgcag ctgcaaaaca agctgaagtg
     7081 gctgaagaaa aagaagaagt tgcgccagca gctcttcaaa atgaaacact tgtaactcct
     7141 atcgtcggtg atgttgtcgc tcttgctgat gtcaatgacc cagtcttctc aagtggagct
     7201 atgggacaag gtatcgctgt gaaaccaagt caaggcgtgg tctatgcact agctgatgct
     7261 gaagtttcaa ttgcctttcc aacagggcac gcttttggtt tgaaaacaag aaatggtgct
     7321 gaagttttga ttcacgttgg tattgacact gtatctatga acggtgacgg ttttgaagca
     7381 aaagttgctc aaggtaataa ggtgaaagct ggcgatgttc ttggaacatt tgactcaaac
     7441 aaaatcgctg cagctggact tgatgataca acaatggtta tcgttacaaa tacagctgac
     7501 tacgcttcag tagctccagt cgcaacaggt tcagtttcga agggggatgc tgtgatcgaa
     7561 gtgaaaatct aatcaatcct ctctaatgtg aaaacgaaca aatgacatgt ttgttcgttt
     7621 ttattagata gtaagattta cagaggaaaa tctaaaaaat agagacattt agactttcga
     7681 agtatgctat aataaagaaa ataaaaacaa gaggtttatc atgacaaaat tatatggaag
     7741 cttggaagcg ggcggtacaa agtttgtctg tgctgtcggt gatgaaaact ttaacgttgt
     7801 agaaaaaaca caatttccaa caacaactcc aatcgaaaca atcgataaaa ccattgagtt
     7861 cttctcaaaa ttcgataacc ttgctggtct tgcagttggt tcatttgggc cgattgatat
     7921 tgacaaaaac tcaaaaactt atggctttat cacgacgact ccaaaaccaa actgggcaaa
     7981 tgtggacttg cttggtgccc ttcgtcgcgc cctaaacgtg ccaatgtact tcacaacaga
     8041 cgtaaacagc tctgcttacg gtgaaatggt tgctcgtaac aatgctggtg gtcgtatcga
     8101 aaacttggtt tactacacaa tcggtacagg tatcggtgca ggcgtcatcc aacgtggtga
     8161 gtttatcggt ggtgtgggtc accctgaaat gggtcattat tatgttgcta gacacccaat
     8221 ggatattgaa aaagagttta agggtgtttg tcctttccat aagggatgtc tagaaggtta
     8281 tgcagctggt acaagtttgg aagctcgtac aggtgtacgt ggggaaacta ttgaactcaa
     8341 caaccctgtt tgggatgttc aagcctacta tatcgctcaa gctgcggtta atgcgacagt
     8401 gactttccgc ccagacgtga ttgtctttgg tggaggggtc atggctcaac aacatatgct
     8461 ggaccgtgtc cgtgagaaat ttacatctct tcttaatggt tacctaccag taccagatgt
     8521 gcgtgactat atcgtgacgc cagcagtcgc aggaaatggt tctgccacac ttgggaactt
     8581 tgttcttgca aaagaagttt caaaataaag cacaaaatcc gcttgggaaa ccaaacggat
     8641 tttgtggttg aaaacaatat ttttgagcct ttccttaagt gattacggac ggtagcgact
     8701 ttcttcgaaa ttccatacct aaactttgag cctagtgtct caaagtttcc gaatacctga
     8761 aaccattaga tttcaggtgt ttctatcacg gcggaaaggc taggtaagtc ctcgcctcac
     8821 tatcgaaaaa tatgcataat ttccatacca aagtatattt agtatcaagc tatagttaat
     8881 ctacgcttta aaaatccact tgggaaacca aacggatttt ttacgtgtca aagcatttgc
     8941 cagaaaaagt caataatata ggtcagaccg taggtataaa ccacgagggt aaagggtttg
     9001 gtcagaatga tgatagtcat gtagcgcttg aaactcatct tggtcagggc ggccagcata
     9061 cagagaaagt cagctgggct aatgggccaa atcatcataa aaataaagaa gcggtcaaaa
     9121 cgattgccct tatctagcca gccgatgtac ttgtcgtagg tgcgcttgct gacgacagac
     9181 tggacaaagg cagctccgta taggcgcact agataaaaga taatggcaca gccaatcacg
     9241 atgccgatat agttgtagat agtcccgatg atgtgcccgt agataaagac cccagccacc
     9301 gaggtcaagg cccctggaat gatagggacg acagtctgta aaatctgtaa aaagataaag
     9361 agaggtggac cccagatgcc tgcctgctgg ataaaggcag agagggtttc cttggattgt
     9421 aaaatcccag cctgataagc ccaaatacag aaaatcaaac tcccaacccc accgacaatc
     9481 gatgagatat tgataactcg ctgcagaagg ggagaaacag ctttcatttg tttatcctgt
     9541 gacatgtaaa ctcctcatag atagtatatt tctactatac catattttgg aggagaaagg
     9601 gggaatgagt cttttttgat aaggaataga aagtaaatag cccttcgaga cttagaatag
     9661 gtctgtcaac taaaggttat atgcattcta ggtttcgaat aatcgcaatt ccataaattt
     9721 aaaagtattc taagtttcga atagcttatc tgagataatt ttgaggcatt cgcgctttcg
     9781 aatagtcatt ttccctaaag tttatatgta ttctgaagct agaaagacta aaatataaaa
     9841 gtagtaagag tctctctctg atggacgtaa tttatggcta gtatgaatcc tttgaattgt
     9901 tagttaattt taatattaat cagttctgaa ataattacta aatatagtta gatggtgagt
     9961 taattattgc taaatttcaa gttcaagtta gtcatccaga agtcttctct gggggacttg
    10021 tagttcaagc attttttagg atagttgtta atccactttt cgataaatgc gacttccttt
    10081 gtagttgttt tcttagttcc ctgaggtaac catctatgaa tgagcctgtt gtgattttca
    10141 ttagatccta tagtgatgtg cataatagat atagcagatt gaaactagaa tagtatacat
    10201 ctacttctaa aacattgtta gaaatcaatt tgactgtcct gatcaatttg tcctgttttt
    10261 atttcatttt actatataat ccttagaaaa catatcggac aagcggttga attccgttcc
    10321 gtccattagt agataaagga ttactccttc ttgaaatgac agatgaactt gtttcttata
    10381 aaaatgttgt ctgaaactat tagccttttt ccagaagttt tagaggaaga aaactttacg
    10441 aggaaaaagg agttactcaa ataacaattc aggattaaaa atagacagtt gaggagcgga
    10501 aggtataaat taagtttgct actgtataat ggatttatca ctaatactct tcgaaaatct
    10561 cttcaaacca cgtcagcttc gccttgccgt agatatagtt actgacttcg tcagttctat
    10621 ccacaacctc aaaacagtgt tttgagctga cttcgtcagt tttatctgca acctcaaagc
    10681 tgtactttga gcagcctacg gctagcttcc tagtttgctc tttgcttttc attgagtata
    10741 aaagtgctcc aggccatatt ttacacagca atagtcttct aaaaatggac aaaaacattg
    10801 taaaggctat caaaaaggag tataatgagt gcaagaaatt tcggaggtga aagatgctag
    10861 aagtaagaag tctagagaaa agttttggct ccaagcaagt tttgtttggt attgactttc
    10921 aagcgcgacc aggtcgtatt ttgggactag tcggaaaaaa tggtgctgga aaaacaacga
    10981 ttttccatag tattttgaaa ttcctagaat atcagggaga aatcggtctg gatggtcagg
    11041 atattcgtca ggagacctat gctcggattg gttatctgcc tgaagaacgc agtctcatgc
    11101 ctaaattgac agttcttgaa caagttcgct acttggcgac tctaaaaggc atggatgcca
    11161 aagaagtcaa agaaaaactc cctcaatgga tgaagaggtt ggaagtgaaa ggaaagctga
    11221 cagataaaat caagagtctg tcaaaaggaa atcagcagaa gattcagctc attattactc
    11281 tgattcatga accagacctg attatcttgg atgagccttt tagtggattg gacccagtta
    11341 atacagaatt gctcaaacaa gtcatttttc aggaaaaaga gcgcggagca accattatct
    11401 tttctgacca tgtcatgacc aatgttgagg aactttgtga cgatattctg atgatccgag
    11461 atggccgtgt ggtcttgcac ggaccagttc aggatgtccg caatcaatac gggaaaacgc
    11521 gtctctttgt ttcaagtgaa cgaagcaagg aagaattgga aaatcttcct catgtcaaac
    11581 aggtgagctt gaccaaacaa ggcagttgga aattgatttt ggaggatgag agcgctggaa
    11641 gggaactctt cccaatcttg actcaaggtc aatatatcgc aacatttgac caacaagcgc
    11701 caactatcga tgaaatcttt aaactagaat caggagtgga agtatgagaa atatgtgggt
    11761 tgtaatcaag gaaacctatc ttcgacatgt cgagtcatgg agtttcttct ttatggtgat
    11821 ttcgccgttc ctctttttag gaatctctgt aggaattggg catctccaag gttcttctat
    11881 ggctaaaaat aataaagtgg cagtagtgac aacagtgcca tctgtagcag aaggactgaa
    11941 gaatgtaaat ggtgttaact tcgactataa agacgaagca agtgccaaag aagcaattaa
    12001 agaagaaaaa ttaaaaggtt atttgaccat tgatcaagaa gatagtgttc taaaggcagt
    12061 ttatcatggc gaaacatcgc ttgaaaatgg aattaaattt gaggttacag gtacactcaa
    12121 tgaactgcaa aatcagctta atcgttcaac tgcttccttg tctcaagagc aggaaaaacg
    12181 cttagagcag acaattcaat tcacagaaaa gattgatgaa gccaaggaaa ataaaaagtt
    12241 tattcaaaca attgcagcag gtgccttagg attctttctt tatatgattc tgattaccta
    12301 tgcgggtgta acagctcagg aagttgccag tgaaaaaggc accaaaatta tggaagtcgt
    12361 tttttctagc ataagggcaa gtcactattt ctatgcgcgg atgatggctc tgtttctagt
    12421 gattttaacg catattggga tctatgttgt aggtggtctg gctgccgttt tgctctttaa
    12481 agatttgcca ttcttggctc agtctggtat tttggatcac ttgggagatg ctatctcact
    12541 gaataccttg ctctttattt tgatcagtct tttcatgtac gtagtcttgg cagcattcct
    12601 aggatctatg gtttctcgtc ctgaggactc agggaaagcc ttgtcgcctt tgatgatttt
    12661 gattatgggt ggtttttttg gagtgacagc tctaggtgca gctggtgaca atctcctctt
    12721 gaagattggt tcttatattc cctttatttc gaccttcttt atgccgtttc gaacgattaa
    12781 tggctatgcg gggggagcag aagcatggat ttcacttgct attacagtga tttttgcggt
    12841 ggtagcaaca ggatttatcg gacgcatgta tgctagtctc gttcttcaaa cggatgattt
    12901 agggatttgg aaaaccttta aacgtgcctt atcttataaa tagaagagcc ttgcgaaagc
    12961 gaggttttta aaggtgaaaa gggtggaatc acgaacctaa tgatgtacac attatgtaaa
    13021 caggttgctt gaaaactcaa ttgtatagtg aactgaatct ggaataggat aatattactt
    13081 ctaaaacatt cttataaatt gatttgaatt ccaaaatccc atcgttccgt tcttatttca
    13141 ttttgcgata tagtgaaagg aaataagtca gctcacaaaa aacgcataat atcaaggatt
    13201 tttaacactt gatactatgc gttttctaat tttaaagact ttttgcctgg tctcttttgt
    13261 tctatgagta tgttacatat ctaggtaaaa attatttaaa gcaaattaac cttatttctc
    13321 aagatgtagt aggttccgag ataaaagata gctatgaata tgagttcttt aacaatggct
    13381 atacctgctc ccatatagaa atggtcattg agtcctacca gtgaattgac atagaaatta
    13441 gaactaagat tgaagaaaag ttcaataaat ccaatgacga tttggatacc aatgtaggct
    13501 gcaacagcga gtgctgtacg gtattcattg aaaagctgtc caatggaaat agccaggtag
    13561 atgcagagga ttcctgaaat ggtatttagt aggaaggata tacctgtaag aaagatctga
    13621 gggagatgtg tttctacaaa tgtaatcaca taagaaagag gaatccattc tggagctgtt
    13681 aaagccagaa taataacagc acttagagcc aatacagcgg tgctaatcaa tgaccagata
    13741 aaggcaccga ttagtttggc tgtgatgata tggtgttcag aaactggcaa ggtcaaagtc
    13801 agatagcctt gtcggtcgta gacactacct ttgaagcgtt taataatcaa gaaaatggtt
    13861 gaaatcgcaa gtgtaagcat caagccacca aagactgtag ctagaaaaag tagcatagta
    13921 gcctgacttt cttggtaagg tagattttta aagccttgtg tctgtattcc gatgagggca
    13981 gaaaggacta gcacggctgc gtagagggct aaataccact tgttaacatt tttaaattcg
    14041 tagtgaacta aattccaaaa cataaataat ctcctttgct taggccttaa attcctgacg
    14101 gaagagttgg tcaatggatt cacctgactc gtagcgaata tcatctacat ttccttgacg
    14161 gacgactttt ccgtctttta ggaagacaat ttcatccaag attggctcga tatcagaaat
    14221 caagtgggta gaaatcaaaa cggtagaagt tggtgagtag ttgttgataa tggtattgag
    14281 gatataagca cgggctgctg gatccacccc accaatgggt tcatccaaaa catagagacg
    14341 agcatcacgg ctcataacca aaatcagttg aaccttttct ttgtttcctt ttgatagttt
    14401 cttgagacga ctattttcat caatgcccag gtctgcaagt agatgatgag cgcgttcaag
    14461 attgaaatct ttatagaagg tcttgaagta ggttagggct tctttgacct tcatttgctc
    14521 attgagatag gtcgtatcag gcaaataagc tacaacggcc ttggttgctg ggcttgggtc
    14581 catgtcgttg atgaggacac gtccttgatc tggttgtaag aggccattaa ttagtttaat
    14641 cagggttgtt tttcctgagc cgtttggccc aagaaggccg acaatttttc cagctggaat
    14701 gtcaagagaa acattttcaa gggctggtgt tgctccatat gatttggata cattttcaaa
    14761 tactagtaat gacataggct taaactcctt taatataatc actgactacg cctggtagtt
    14821 cttctttttc atagccaaaa tggatcatgg aggaaacgaa gtgttccaat tcttcttctg
    14881 ataattgttt gcgtgactga gcgattagct ccttatcctt agtcacaaat cgtccagttg
    14941 ttcgcttgct gtagacaaat ccttctcgtt caaggtctga taaggctctt tggatggtat
    15001 tgggattgac accagcctcg ctagctagct ccctcacggt tggaagttgt tgattgggtt
    15061 ccagtgtatg ggaaacaatc tgaagcttga ttttctccat aatctgtaaa tagatgggtt
    15121 ttttgttgtc aaatgtccag gacatcttag tctcctttct cttatccttt tgtcttaact
    15181 aaataataca acaaaacaaa aaacttgtca agcaaaaaga agaattgttt tgggaatcgc
    15241 ttaaaaaatg gtataatgaa aagaaaacga taaggaggga aaggatgcgt tgtccaaaat
    15301 gtggggctac caagtcaagt gttatcgata gtcgccaagc agaagaaggg aacaccattc
    15361 gtagaagacg tgagtgcgac gaatgccaac accgttttac aacctacgaa cgagtagaag
    15421 aaagaacctt agtggttgtt aaaaaagatg gtacacggga acaattctcc agagataaaa
    15481 tctttaatgg gattatccgc tcagcccaga aacgtcctgt gtcaagtgat gaaatcaaca
    15541 tggtagtcaa tcgtatcgaa cagaaactcc gtggtcgaaa tgaaaatgaa attcaaagtg
    15601 aggacattgg ttcactcgtc atggaggagt tggctgaatt ggacgagatt acctatgtac
    15661 gttttgctag tgtctatcgt agttttaagg atgtcagtga gttagagagc ttgctccaac
    15721 aaatcaccca gtcctctaaa aagaaaaagg aaagataaat gaagccaatt gaccgttttt
    15781 cttatctaaa gaataatcgg gtgtcgcaag atacctcatc tctggtacag tgctacctcc
    15841 cgattatcgg tcaggaggca ctgagccttt atctttatac aatcagtttt tgggataatg
    15901 gtagaaagga atatcttttt tcaagtatcc tcaatcatct caactttggg atggatagac
    15961 tgataaaatc attgaaaatc ttatctgctt ttaatctctt gaccctctat caaaaggggg
    16021 atgtttatca gctagccctc catgctcctc tatctagtca agacttcttg gagcatcctg
    16081 tttatcgcag actcttagag aaaaagattg gcgactctgc tgtggaggat ttgaaagttg
    16141 aaagtgctga tggtgaagaa atacctgtct cactcaatca agtctttcca gaattggcag
    16201 aactaggcag tcaagaagac cttggtctca agaagaaagt ggccaatgat tttgacttgg
    16261 aacattttcg ccagctgatg gctcgagatg gacttcgttt tgcggatgag cagtccgatg
    16321 tcttaaacct ctttgctatt gccgaggaga agaaatggac ttggtttgaa acctatcaat
    16381 tggccaagtc aacagctgtt tctcaggtta tttcaaccaa acgcatgcgt gaaaaaattg
    16441 ctcaaaaacc agtttcctct gactttaatc ctaaggaagc aaccattatc aaggaagcta
    16501 aaagtaagac tgccctgcag ttcttagcag aaatcaagca aacacgcaag gggaccatta
    16561 cccaaacaga aagagaactt ttgcaacaga tggctggctt gggcttgctg gacgaagtca
    16621 tcaatatcat tctcttgttg acctttaata aggtggattc ggcaaacatc aatgagaaat
    16681 atgccatgaa ggtggctaat gactatgcct atcaaaagat acattcagca gaagaggccg
    16741 ttttacgaat tcgtgagcga gggcagaaaa caaaaacaca aaaacagaat cagactgccc
    16801 cagcaaaaac caatattcct aaatggagta acccagatta taagaatgaa accagcgagg
    16861 aaactcgtct ggaactagaa cgtaagaaac aagaactatt agctcgatta gaaaaaggag
    16921 gagattagat ggaaagtgtc ggagacgtac tcaaacgtca acccagccgt ttttattatc
    16981 aagatttggt ccagaaaatc atgaaggacc ctgatgttgc ggcttttatc cagcaagaat
    17041 ccttgactcc agaggaatta aatcgcagta tctccaagtt taatcagtac atcaccgagc
    17101 gtgacaagtt tctccgtggg gatacggatt atattgccaa aggctacaag ccgattttgg
    17161 ttaagaatca tggctatgca gatgtttcat atgaagaaac tcctgagcta atcgcggctg
    17221 aaaaagaagc ggctattaag aatcgtctca agctaatcaa tctaccagcc agtctcaaaa
    17281 aagctagttt ggctcaagtt gatttggatg atttgggacg cttgccagtt tttgaaaaac
    17341 tattagcctt tgtggagcaa tatccagcta ttcgaaaagg tctttactta tatggagact
    17401 ttggtgtggg taaaagtttc atggtggcgg ccttagctca tgatttatca gaaaaacgtg
    17461 gtgtttcatc aactctcctc cactatccta gctttgtcat tgatgtcaaa aatgctatca
    17521 gtgatggcaa tgttaagacc ttggtggatg agattaagct gtctgaggtc ctgattttag
    17581 atgatattgg cgccgagcaa tcaaccgctt gggtgcgtga cgaaatcctg caggtcattc
    17641 tccaatatcg gatgcaggaa aatttaccga cctttttcac atccaacttc aactttgaag
    17701 atttggagaa gcattttgcg aaagtgaaac atggaaatga cgaaacctgg gaagccagac
    17761 gggtcatgga acgcatccgt tatttggctg aggagactcg tttagaagga gtaaaccgtc
    17821 gatgacagaa accattaaat tgatgaaggc tcatacttca gtgcgcaggt ttaaagagca
    17881 agaaattccc caagtagact taaatgagat tttgacagca gcccagatgg catcatcttg
    17941 gaagaatttc caatcctact ctgtgattgt ggtacgaagt caagagaaga aagatgcctt
    18001 gtatgaattg gtacctcaag aagccattcg ccagtctgct gttttccttc tctttgtcgg
    18061 agatttgaac cgagcagaaa agggagcccg acttcatacc gacaccttcc aaccccaagg
    18121 tgtggaaggt ctcttgatta gttcggtcga tgcagctctt gctggacaaa acgccttgtt
    18181 ggcagctgaa agcttgggct atggtggtgt gattatcggt ttggttcgat acaagtctga
    18241 agaagtggca gagctcttta acctacctga ctacacctat tctgtctttg ggatggcact
    18301 gggtgtgcca aatcaacatc atgatatgaa accgagactg ccactagaga atgttgtctt
    18361 tgaggaagaa taccaagaac agtcaactga ggcaatccaa gcttatgacc gtgttcaggc
    18421 tgactatgct ggggcgcgtg cgaccacaag ctggagtcag cgcctagcag aacagtttgg
    18481 tcaagctgaa ccaagctcaa ctagaaaaaa tcttgaacag aagaaattat tgtagaaagt
    18541 gagaaattat ggccctacca actattgcca ttgtaggacg tcccaatgtt gggaaatcaa
    18601 ccctatttaa tcggatcgct ggtgagcgaa tctccattgt agaagatgtc gaaggagtga
    18661 cacgtgaccg tatttatgca acgggtgagt ggctcaatcg ttcttttagc atgattgata
    18721 caggaggaat tgatgatgtc gatgctcctt tcatggaaca aatcaagcac caggcagaaa
    18781 ttgccatgga agaagcagat gttatcgtct ttgtcgtgtc cggtaaggaa ggaattaccg
    18841 atgcagacga atacgtagcc cgtaagcttt ataagaccca caaaccagtt atcctcgcag
    18901 tcaacaaggt ggacaaccct gagatgagaa atgatatcta tgatttctat gctctcggtt
    18961 tgggtgaacc attgcctatc tcatctgtcc atggaatcgg tacaggggat gtgctagatg
    19021 cgatcgtaga aaatcttcca aatgaatatg aggaagaaaa tccagatgtc attaagttta
    19081 gcttgattgg tcgtcctaac gttggaaaat caagcttgat caatgctatc ttgggagaag
    19141 accgtgttat tgctagtcct gttgctggaa caactcgtga tgccattgat acccacttta
    19201 cagatacaga tggtcaagag tttaccatga ttgatacggc tggtatgcgt aagtctggta
    19261 aggtttatga aaatactgag aaatactctg ttatgcgtgc catgcgtgct attgaccgtt
    19321 cagatgtggt cttgatggtc atcaatgcgg aagaaggcat tcgtgagtac gacaagcgta
    19381 tcgcaggatt tgcccatgaa gctggtaaag ggatgattat cgtggtcaac aagtgggata
    19441 cgcttgaaaa agataaccac actatgaaaa actgggaaga agatatccgt gagcagttcc
    19501 aatacctgcc ttacgcaccg attatctttg tatcagcttt aaccaagcaa cgtctccaca
    19561 aacttcctga gatgattaag caaatcagcg aaagtcaaaa tacacgtatt ccatcagctg
    19621 tcttgaacga tgtcatcatg gatgccattg ccatcaaccc aacaccgaca gacaaaggaa
    19681 aacgtctcaa gattttctat gcgacccaag tggcaaccaa accaccaacc tttgtcatct
    19741 ttgtcaatga agaagaactc atgcactttt cttacctgcg tttcttggaa aatcaaatcc
    19801 gcaaggcctt tgtttttgag ggaacaccga ttcatctcat cgcaagaaaa cgcaaataaa
    19861 aaagtagaat ctggaatgac agttccggat ttttttgata taataaaata atagaaaacg
    19921 ctatcaaaag aaggagggtg atgtcggtga tggaacattt gtttaaattc ttacttttag
    19981 caccgtactt ttattttgat aactggattg agaaggccaa cagaaatagt aagttttttc
    20041 caatttttta ttatttttac tggttttaca tccccttcta ttctcttttt agccttgctt
    20101 ggacagttgt ttcagttctg tttttcaata ccgtcttgag aaatgtgaca gatatcaagt
    20161 tatggggcat ttggtttctt tttattctgc tagctattgg tatgaattgg ttaacttatt
    20221 cctgtttcaa agaaatgttt cgcttgagac aggaactagg gaagtctaag ggtggaaggc
    20281 attgatttat atcggtttct atttgtagga ggtggcttat ggtacctcta aaatcattta
    20341 ttacacgcta ttccaaggtt tatattggta ataacattta atagaacgaa actaaagaaa
    20401 acaatttaaa agaggaggtt tgtgatggaa tacttgttta aaatgataat cttattaccc
    20461 tgtttttact ttttcagctg gattgaaaag gcaaacagag atagtaagat tttcccaatt
    20521 ttttactatt tttactggat ttacatcacc ctctatgctc tttttagcct tgcttggaca
    20581 gttttttcag ttctgttttt caatatcgtc ttgagaaatt tgacagatat caagttatgg
    20641 ggtatttggc tattattact acttatcgct tttgctagtg actggttaga ctatatctgt
    20701 ttcaaaaaaa tgcttgactt gagacgggaa ctagggaagt ctaaaggcgg aaggcattga
    20761 tttatactct tcgaaaatct cttcaaacca cgtcaacgtc gccttggatt atatatgtaa
    20821 ctgacttcgt cagtcttatc tacaacctca aagcagtgct ttgagcaact tgcggctagt
    20881 ttcctagttt gctctttgat tttcattgag tattatatta ctttctattt gtaggaggtg
    20941 gcttatgaag attcctctct taactttggc aaggcataaa tttgtttatg tcttgcttac
    21001 tttgcttttt cttgctttgg tttatcgtga tgttttgatg acttatttct tttttgatat
    21061 tcatgcgccc gatctagcta aattcgatgg acaagcaatt aaaaatgact tattaaaatc
    21121 agcattagat tttcgtattc tccagttcaa tctaggtttt tatcaatcat ttattattcc
    21181 aatcatcatt gttttgctag gttttcaata tattgagctg aaaaataaag ttttacgatt
    21241 gagtattgga agagaagtga gctatcaagg gttaaaaaga aagttgactt tgcaagttgc
    21301 aagtatccct tgtttgatat atttagtgac tgtgctgata attgcaatta taacctattt
    21361 ctttgggact ttttctcctc ttgaatggaa ttctctattt tctgatggga gtggtttaca
    21421 aagactccta gatggagaga taaaaagcta tttgttcttt acttgtgtcc tactaatcgg
    21481 tattttcatc aatgcaatct attttttaca aatagttgat tatgtgggga atgtgactcg
    21541 ttcggcaatc acctatttga tgtttctttg gcttggttct atgctgctct atagtgcctt
    21601 gccttactat atggttccta tgacgagttt gatgcaagct agctatgggg atgtaagttt
    21661 gatgaaactc tttactcctt atatccttta tgttgtccct tatatggtac ttaaaaaata
    21721 tgaagataat gtttaagaat tttaacaata tttggctaaa gagaaagatc gttttactac
    21781 ttcgtatagt tctgatgatg attttgataa actatctatt gtcaacagcg gttcaaaagc
    21841 aggatgctgt tatctttttc aagagagaat tgatttcaat tttttcctat aatgactatt
    21901 ctgaagcgaa tttagaaatc cccaaactct tgttaaacct ttcgcttttc atggtaggat
    21961 ggctctctgt cattttactt gaaagtgatt tggcagacca ttaccatcac ttgattcgct
    22021 atcaatcaag ctcctttttc gattatacaa ggaaacgatt ggttgtcatt tctaaatttt
    22081 ttactcaaga tttgtttgtc tggtttcttg gtttacttcc gctaggaatt catttcaaaa
    22141 cagtcgcact tttcttttta cttgctcagt taatgatgtt gtacttacta ctgtcttatc
    22201 tgatagcact gattagtgcg ggcgctggtt tttctttttt tctctatttt ttggcatttg
    22261 tgggacaaga atggatgatg gatcatattg taacagtgta tttagtactc ttaagcttat
    22321 tagttatgtt gattgttagt cgcttggaag agaaatttaa gaaaggataa acgatgagac
    22381 ttgaaattat aaatggacag aaaatttatg ggaaaagacc tattttaaat cagttgaatt
    22441 tggtgtttca atcaggaaaa atttatggac ttaaaggtga taatggatct ggcaagacgg
    22501 ttcttttaaa gatacttgct ggttatatta agcttgacaa aggaaaagtt cttcaagatg
    22561 gtaaagttta cggggtaaaa aatcattata ttcaggatgc aggaatttta attgaaaaag
    22621 tcgagttttt atctcattta tccctgagag aaaatttgga actgttaagg tatttttcat
    22681 ctaaagttac ggaaaaaaga attgcctatt ggattcaata ctatgattta caggaatttg
    22741 aagacgttga ataccgtcat ttatccttgg gaacaaagca aaaaatggcc ttgattcaag
    22801 cctttatttc ctctccttct atactctttc tcgatgaacc tatgaatgct ttggatgaga
    22861 agagtgtgag gttaaccaaa caggtcattt tatcttacct gaaaaaagaa aatggtctgg
    22921 ttatcctgac gtcgcacata tcggaagata tttcagacct ttgtacagat gtattagttg
    22981 tcgaaaatgg acatatacaa tatgtaaagg atatacaatc ctaggagatg gcttatggca
    23041 catctaaaat catttattac acgctattcc aaggtttata ttggtttagt tctgctgatc
    23101 tggctgtctt tcttctttat cccttgggat agagcgattc tgggggtaag gattgacatc
    23161 ttcatcatgc agaaaatctt gctagctttt ggaattctgt ccattctcat ggccttgctg
    23221 tccaagaaag tcagtctctt tgtttttgga ctgatttgct gtctttctct ttggattaac
    23281 ttatttatca catttgccat tttgccgatt tttggcaatt aaacagtcat aaaagtcgga
    23341 gaggttagct tgaaaactaa cctctttttc cttttcaaaa tggggattct tccttgaaaa
    23401 taatcagtaa ttgtgctaaa attaaaggaa cattctaaaa tattcggaat ttaaagtaag
    23461 gaaaaacatg gctaatattt taaaaacaat tatcgaaaat gataaaggag aaatccgtcg
    23521 tctggaaaag atggctgaca aggttttcaa atacgaagac caaatggcta ctttgactga
    23581 cgaccaacta aaagcaaaaa cagttgaatt taaggaacgt tatcaaaatg gagaatcact
    23641 ggattcattg ctttacgaag catttgcggt tgtccgtgaa ggtgccaaac gtgtcctagg
    23701 tctcttccct tataaggttc aggtcatggg ggggattgtt cttcaccatg gtgacgtgcc
    23761 agagatgcgt acaggggaag ggaaaacctt gactgcgacc atgccggtat acctcaatgc
    23821 cctttcaggt aaaggggttc acgtagttac ggttaatgaa tacctgtcag aacgtgacgc
    23881 gactgagatg ggtgaattgt actcttggct tggtttgtca gtagggatta acttggctac
    23941 caaatctcca atggagaaaa aagaagccta tgagtgtgat attacttact caactaactc
    24001 agaaatcgga tttgactacc ttcgtgacaa catggtcgtt cgcgccgaaa acatggtaca
    24061 acgtccgctt aactatgcct tggtcgatga ggttgactct atcttgattg acgaggctcg
    24121 tacacctttg attgtatcag gtgccaatgc ggttgaaacc agtcagttgt atcacatggc
    24181 agaccactat gtaaaatctt tgaacaaaga tgactacatc atcgatgtgc agtctaagac
    24241 tattggtttg tctgattcag ggattgacag ggctgaaagc tacttcaaac ttgaaaacct
    24301 ctatgacatc gaaaacgtgg ctttgactca ctttatcgat aacgcccttc gtgccaacta
    24361 catcatgctt ctcgatattg actatgtggt gagcgaagag caagaaatct tgattgtcga
    24421 ccaatttaca ggtcgtacca tggaaggtcg tcgttattct gatggattgc accaagctat
    24481 tgaagccaaa gaaggtgtgc caatccagga tgaaaccaag acatctgcct caatcacgta
    24541 ccaaaacctt ttccgtatgt acaagaaatt gtctggtatg acgggtacag gtaagactga
    24601 ggaagaagaa ttccgtgaaa tctacaacat tcgtgttatt ccaatcccaa caaaccgtcc
    24661 tgttcaacgt attgaccact cagaccttct ttatgcaagt atcgaatcta agtttaaagc
    24721 ggttgtcgaa gacgttaagg ctcgttacca aaagggtcaa cctgtcttgg ttggtacagt
    24781 agcggttgaa actagtgact acatttctaa gaaattggtt gcagctggtg ttcctcacga
    24841 agtcttgaat gccaaaaacc actatagaga agcccaaatc atcatgaatg ctggtcaacg
    24901 tggtgccgtt accatcgcaa ccaacatggc gggtcgtggt accgacatca agcttggtga
    24961 aggtgttcgt gaacttggag gactttgtgt tattggtaca gaacgtcatg aaagtcgtcg
    25021 tatcgataac cagcttcgtg gacgttcagg tcgtcaagga gatccaggtg agtcacaatt
    25081 ctacctatct cttgaagatg atttgatgaa acgttttggt tctgaacgct tgaagggaat
    25141 ctttgaacgt ttgaacatgt ctgaagaggc gattgagtct cgcatgttga cgcgtcaggt
    25201 tgaagcagct cagaaacgtg tcgaaggaaa taactacgat acccgtaaac aagtccttca
    25261 atacgatgat gtcatgcgtg aacaacgtga gattatctat gctcaacgtt acgatgtcat
    25321 cactgcagat cgtgacttgg cacctgaaat tcaggctatg atcaaacgca cgattgaacg
    25381 tgtcgttgat ggtcatgcgc gtgccaaaca agatgaaaaa ctagaggcaa ttttgaactt
    25441 tgctaagtac aacttgcttc ctgaagattc tattacgatg gaagacttgt caggcttgtc
    25501 tgataaggcc atcaaggaag agcttttcca acgtgccttg aaggtttacg atagtcaggt
    25561 ttcaaaacta cgcgatgaag aagcagttaa agaattccaa aaagttttga ttctacgagt
    25621 ggtggataac aagtggacag atcatatcga tgcccttgat caattgcgta acgcggttgg
    25681 acttcgtggc tatgctcaga acaaccctgt tgttgagtat caggcagaag gtttccgtat
    25741 gtttaatgat atgattggtt cgattgagtt tgatgtgaca cgcttgatga tgaaagcaca
    25801 aattcatgaa caagaaagac cacaggcaga acgtcatatc agtacaacag cgactcgcaa
    25861 tatcgctgct caccaagcaa gtatgccaga agatttggat ttgagccaga ttggacgcaa
    25921 tgaactttgc ccatgtggtt ctggtaagaa atttaaaaac tgtcacggta aaagacaata
    25981 aaatgagata gtttagaggc ggatatcttg tgaaaagtaa atttttactg ggtatccgtt
    26041 tgctttataa ggagatgagt tatggtattt acagcaaaaa gctctaaaat aaatatagaa
    26101 gaagttcgtg ccttgtcaaa attagaaggt caggctttgg agaggaaatc acagcgcgat
    26161 caagagctag aagccattat acgtggagaa gatcagcgaa ttctcttggt aatcgggcca
    26221 tgctcatctg acaacgaaga agctgtcctt gaatacgcta agcgtttggc agtcctacaa
    26281 gaagaagtgg cagatcgtat ctttatggtt atgcgtgttt atactgccaa accccgtacc
    26341 aacggagatg gctataaggg cttgattcac cagcctaacg cgacagaagc gcctagtctt
    26401 atcaatggaa tcaaagccgt tcgccatctt cactatcgtg tcatcacaga aacagggatg
    26461 acaactgctg atgaaatgct ttatcctgaa aaccttccgc ttgtagatga tttgatttct
    26521 tacatggcag ttggtgcccg ttcagttgaa gaccagcaac accgctttgt ggcaagtggg
    26581 gcaggatttt ctactggttt taaaaatcca acctctggaa atctcaatgt catgtttaat
    26641 gggatttatg ctgctcaaaa caaacaaagt ttccttttct taggaaaaga agtagaaaca
    26701 actgggaacc cgctttcaca cgctattctt cgtggtgctc ttaatgagta tggaaaaaat
    26761 attcccaact actattatga caatttaatt gataccattg cccaatatga gaaaatgggc
    26821 ttggaaaatc cttttatcat cattgatacc aatcatgaca attctggtaa gcagtatatt
    26881 gaacagatcc gaattgtccg ccagaccttg attaaccgtg cttggaatga aaaaattaag
    26941 cagttcgttc gtggttttat gattgagtct tatctggaag atggtcgaca aaatgagcca
    27001 gaagtatttg gcaagtctat cacagaccct tgcctgggtt gggataacac agaagctctt
    27061 gtcagagaaa tttacaaaac gttaggagaa taagatggca tttattgaaa aaggtcaaga
    27121 aatcgatatg gaagtcatca aggctgaaac ccaattgtct gcggaagcct tgagactcaa
    27181 ggaaagccgt gacagggaat tggcagatat tatttcaggg gaagatgacc gtattctctt
    27241 ggtgattggt ccttgctctt ctgataatga agaggcggtc ttggaatatg ctcgccgttt
    27301 atccgccttg caaaagaagg tagcggacaa gattttcatg gtcatgcgcg tgtatactgc
    27361 taagcctcgt accaatggag acggctataa aggattggtt caccagccag atacttctaa
    27421 ggctccaagc ctgattaacg gtttgcaggc tgtgcgccag ttgcattacc gcgtgattac
    27481 agagactggt ttgacaacgg cagatgagat gctttatccg tcaaatctga tcttggtgga
    27541 tgacttggtc agctaccatg ccgttggagc tcgttctgtg gaagaccaag agcaccgctt
    27601 tgtggcttct gggattgatg caccagtagg gatgaaaaat ccaacctcag gaaatttggg
    27661 tgttatgttt aacgccatct atgctgctca aaacaagcaa accttccttt atcatgggca
    27721 ggaagttgag acatcaggta atcctttggc ccatgttatc ctccgtggag cagtcaacga
    27781 gtatggcaat tatatgccga attactacta tgaaaaccta ctccaagcca ttgaacgcta
    27841 tgaaaccatg ggacttgaaa atccttttat cctcattgac accaaccatg ataactcagg
    27901 caagcaatat atggagcaga ttcgaattgt tcgccagacc ttgcagaatc gtgattggaa
    27961 tgagaaaatt aaaaagacgg ttcgaggatt tatgattgaa tcttacctag cagatggtcg
    28021 tcaaaaccaa ccagagatct ttggttgctc tattactgac ccttgcctag gttgggaaaa
    28081 tacagaggcc ttggtagaag agatttatgt taccttgaca aaataagtga aaaggatgga
    28141 gttggggaat ctcaactcct tttgatgaga atgatagttg gacacggaat tgacatcgaa
    28201 gaattggctt cgatagaaag cgcagttaca cgacatgaag gatttgctaa gcgtgtactg
    28261 accgctcagg aaatggagcg cttcaccagt ctcaaaggac gcaggcaaat agaatattta
    28321 gctggtcgct ggtcggctaa ggaggccttt tccaaggcta tgggaacggg cattagcaag
    28381 ctcggttttc aggatttgga agtattgaac aatgaacgtg gggcgcctta ttttagtcag
    28441 gcaccatttt caggaaagat ttggctgtct atcagccaca ccgatcagtt tgtgacagcc
    28501 agtgtcattt tggaggaaaa tcatgaaagc tagtccacat agaccaacca aggctctgat
    28561 tcatctggga gctattcgac aaaatattca gcaaatgggg gctcatatcc ctcaaggaac
    28621 gctcaagttg gctgtggtta aggccaatgc ttatggtcat ggagctgttg ccgttgccaa
    28681 ggcaattcaa gatgatgttg atggcttttg cgtttccaat atcgatgaag ccattgaact
    28741 cagacaagct ggactcagca agccaatcct cattttagga gtttctgaaa tcgaagctgt
    28801 tgctctagct aaagaatatg acttcacctt gacagtggct ggactggagt ggattcaagc
    28861 actcttagat aaggaagtgg acctaactgg attgacagtc cacctcaaga ttgattcagg
    28921 gatgggacgg attggtttta gagaggcaag tgaggttgag caggctcaag atttgctcca
    28981 acaacacggt gttcgtgttg aaggaatctt tacccacttt gctactgctg atgaggaatc
    29041 agatgactat tttaatgccc agttagaacg gtttaaaact attttagcta gtatgaagga
    29101 agttccagag ctggttcatg ctagcaattc tgcaacgact ctttggcatg tagagactat
    29161 tttcaatgcg gttcgtatgg gagatgccat gtatggtctc aatccaagtg gagcggtctt
    29221 ggctttgcct tatgatttga taccggcctt gaccttggag tctgctctgg ttcatatcaa
    29281 gacagttcca gctggtgctt gcatgggcta tggagcaact tatcaaacgg atagcgagca
    29341 agtcatcgcg accgtgccaa tcgggtatgc agatggatgg acaagagaca tgcaaaattt
    29401 ctctgtcttg gtagatggcc aagcttgccc aattgtcggc agggtttcga tggaccaaat
    29461 cactattcga ttgcctaagc cttacccact cggaaccaag gtaaccttga ttggctccaa
    29521 tggggataag gaaatcactg caactcaggt agcgacctac cgcgtaacca ttaactatga
    29581 ggtggtttgc ctcctcagcg accgtattcc gagagaatat tactagaaaa gaaaggagtg
    29641 gagcatgaat ctacatcaac ccttgcatgt cttgcctggt gtgggaccaa agtcagcaga
    29701 aaaatacgcc aaactaggaa ttgaaaactt gcaagatctc ttgctctact ttcctttccg
    29761 ttatgaagac ttcaaaatca agcaggtgct ggagctggaa gacggtgaga aggcagttct
    29821 ttctggtcag gtagtgactc ctgctagtgt ccagtattat ggtttcaagc gcaatcgcct
    29881 gcgttttagt ctcaagcagg gagaggtcgt ttttgcggtg aatttcttta accagcccta
    29941 tctggctgat aaaatagagt tgggagcaac ccttgctgtc tttggaaaat gggaccgcgc
    30001 taaggctagt ctgactggga tgaaggttct ggctcaggta gaagatgacc tccagcctgt
    30061 ctatcgtctg gctcagggaa tcagtcaggc cagtctggtt aaggtcatca agacggcttt
    30121 tgatcaggga ctggacctct tgatagaaga aaatctgccc cagtctttac tagacaaata
    30181 caaactcatg tcccgttgtc aggcagtccg agctatgcat tttccaaagg atttggcaga
    30241 atacaagcag gctcttcgcc gtatcaagtt tgaggaactc ttttatttcc aaatgcagct
    30301 gcagatgctc aagtctgaaa atagagttca gggaagtggt ctggttctga attggtctca
    30361 ggaaaaagtg acagcagtta aagtaagtct tccttttgcc ctgacccaag ctcaggaaaa
    30421 gagtttgcag gaaattttaa ctgatatgaa gtccgaccac cacatgaatc gtctcctaca
    30481 aggggatgtg gggagtggaa aaacggtagt cgctggcttg gccatgtttg cggcagtgac
    30541 agcaggttat caggctgccc taatggtacc aacagaaatc ctcgcagagc aacactttga
    30601 gagtttacag aacctttttc ccaatttgaa actggctctc ttgacaggtt ccttgaaagc
    30661 tgcagaaaag agagaggtct tggagaccat tgccaagggt gaggctgatt tgattatcgg
    30721 aactcacgct ctgatacaag atggggtgga gtatgctcgt cttggtttga ttattatcga
    30781 tgagcagcac cgttttggtg tagggcaaag gcgtatttta cgggaaaaag gtgacaatcc
    30841 agatgtcctc atgatgacgg cgactcccat tccacggacg cttgccatca cagcctttgg
    30901 agatatggat gtttccatta tcgaccagat gccagcaggt cggaagccta ttgtgacgcg
    30961 ctggatcaaa catgagcaac tacctcaggt cttgacttgg ttagaggggg aaattcaaaa
    31021 aggttcccaa gcctatgtca tctctccttt gattgaagaa tcagaagctc tagatttgaa
    31081 aaatgccatt gccttatcag aggagttgac gactcatttt gcaggcaagg cagaggtggc
    31141 tcttctacat ggtaggatga agagtgacga aaaagaccag atcatgcagg atttcaagga
    31201 gagaaagacg gatattctgg tttcgacgac ggttattgag gttggggtca acgttcccaa
    31261 tgcgactgtc atgattatca tggatgccga tcgcttcggt ctcagtcaac ttcaccagct
    31321 tagaggtcgt gtcggtcggg gggacaagca gtcctacgct gttctcgttg ccaatcccaa
    31381 gacggattct gggaaagacc gcatgcgtat catgacagaa acgaccaatg gatttgtcct
    31441 tgcggaggaa gatttgaaaa tgcgtggttc tggtgagatt tttggaacca gacagtcagg
    31501 acttccagag ttccaagtgg ctgatattat cgaagatttt ccgattttag aagaagcaag
    31561 aaaggttgct agctacatta gttctataga agcttggcaa gaagatccag agtggcgcat
    31621 gattgccctt catctggaaa agaaagaaca tctggattaa gctttctcta aggaaaactt
    31681 aagctagttt ttaggtttgg ctcttatact aaagtcatca aaaagaaacg aggactctca
    31741 tatgacagta acgattaaag taaattacca aaccactttc caaaagaagg aagcaaaaaa
    31801 ctagtataaa cagaagagag agcgaaatgc tctttttcgt ttctaaaact actttcagcc
    31861 catcatccta aaagtaaaga atctaaattc actttctatt tatccttctt tcttgcattg
    31921 attacataga tatgctacag ttgtggtaac gattacaaaa taaaaggagc atgctatgaa
    31981 aaatccagct ttgctagaag aaattaagac ctatagagga agggatgagg ttccggaaga
    32041 ctttgatgct ttctgggatg gggaagtgaa aaatgtttcc acgcttccat cctaccactt
    32101 ggaggaaaga gatttccaca ttcctcaagt caagtgctat gagttaacat ttgaaggaag
    32161 caaggaagga aaggtctatg cacgcattgt tcttccaaag agtgaggaga aggttccact
    32221 aatcttccat tttcatggtt atatgggacg tggctgggac tgggccgaca tgctgggctt
    32281 caccgtagct ggttacggtg ttgtttccat ggatgtgcgg ggccagtcag gttactcaca
    32341 agacggcttg cgttctcctt taggaaatac cgtgaagggg catattatcc gtggtgctat
    32401 ggaaggtcgg gaccacctct tttataagga tgtttatctg gatatttacc agttggtcga
    32461 aattgttgct agtctgtctc aggttgatga gaagcgtctt tctagctatg gtgcctcaca
    32521 aggaggggct ctagctctag ttgcagcagc gctcaatcct cgaattcaga aaacagttgc
    32581 catttatccc ttcttgtcag acttcagacg ggtgattgag attggtaata ctagcgaggc
    32641 ttacgacgaa cttttccgtt atttcaagtt tcacgacccc ttccatgaaa cagaggagga
    32701 aatcatggcg acccttgcct atatcgatgt caaaaatctt gcccatcgta tccaaggtga
    32761 ggttaagatg attacgggct tggacgacga tgtttgctat cccattaccc agtttgcgat
    32821 ttataatcgt ctgacctgcg ataaaaccta tcgcatcatg cctgagtatg ctcacgaagc
    32881 catgaatgta tttgtcaatg accaagtcta caactggctc tgtggaagtg agattccttt
    32941 taaatatcta aaataaggag tcgactctaa gcacaaaatc ttaaaaatta caaacacgca
    33001 tagtatcagg ggattaaaaa aacttgatac tatgcgtttt atcatggaaa tatagtaaaa
    33061 tgaaacaaga ataggacaaa acgatcagga cagtcaaatc gatttctaac aatgttttag
    33121 aagcaaatgt gtactattct agtttcaatc tattatattt atagaatttt ttgttgctag
    33181 atttgtcaaa ttgcttaaaa taattttttt cagaaagcaa aagccgatac ctatcgagta
    33241 gggtagttct tgctatcgtc aggcttgtct gtaggtgtta atacttttca aaaatctctt
    33301 taaaccacgt cagcttcgcc ttgccgtata tatgttactg acttcgtcag ttctatctgc
    33361 cacctcaaaa cggtgttttg agctgacttt gtcagtctta tctacaacct caaaacagtg
    33421 ttttgagcat catgcggcta gcttcttagt ttgctctttg attttcattg agtataaaaa
    33481 cagatgagtt tctgttttct ttttatggac tataaatgtt cagctgaaac tactttcaag
    33541 gacattatta tataaaagaa ttttttgaaa ctaaaatcta ctatattaca ctatattgaa
    33601 agcgttttaa aaatgaggta taataaattt actaacgctt ataaaaagtg atagaatcta
    33661 tctttatgta tatttaaaga tagattgctg taaaaatagt agtagctatg cgaaataaca
    33721 gatagagaga agggattgaa gcttagaaaa ggggaataat atgatattta aggcattcaa
    33781 gacaaaaaag cagagaaaaa gacaagttga actacttttg acagtttttt tcgacagttt
    33841 tctgattgat ttatttcttc acttatttgg gattgtcccc tttaagctgg ataagattct
    33901 gattgtgagc ttgattatat ttcccattat ttctacaagt atttatgctt atgaaaagct
    33961 atttgaaaaa gtgttcgata aggattgagc aggaagtatg gtataaatag cataagctga
    34021 tgtccatcat ttgcttataa agagatattt tagtttaatt gcagcggtgt cctggtagat
    34081 aaactagatt ggcaggagtc tgattggaga aaggagaggg gaaaattggc accaatttga
    34141 gatagtttgt ttagttcatt tttgtcattt aaatgaactg tagtaaaaga aagttaataa
    34201 aagacaaact aagtgcattt tctggagtaa atgtcttatt tcagaaatcg ggatatagat
    34261 atagagagga tcagtatgaa tcggagtgtt caagaacgta agtgtcgtta tagcattagg
    34321 aaactatcgg taggagcggt ttctatgatt gtaggagcag tggtatttgg aacgtctcct
    34381 gttttagctc aagaaggggc aagtgagcaa cctctggcaa atgaaactca actttcgggg
    34441 gagagctcaa ccctaactga tacagaaaag agccagcctt cttcagagac tgaactttct
    34501 ggcaataagc aagaacaaga aaggaaagat aagcaagaag aaaaaattcc aagagattac
    34561 tatgcacgag atttggaaaa tgtcgaaaca gtgatagaaa aagaagatgt tgaaaccaat
    34621 gcttcaaatg gtcagagagt tgatttatca agtgaactag ataaactaaa gaaacttgaa
    34681 aacgcaacag ttcacatgga gtttaagcca gatgccaagg ctccagcatt ctataatctc
    34741 ttttctgtgt caagtgctac taaaaaagat gagtacttca ctatggcagt ttacaataat
    34801 actgctactc tagaggggcg tggttcggat gggaaacagt tttacaataa ttacaacgat
    34861 gcacccttaa aagttaaacc aggtcagtgg aattctgtga ctttcacagt tgaaaaaccg
    34921 acagcagaat tgccaaatgg tcgagttcgc ctgtatgtta atggtgtttt atctcgaaca
    34981 agtctgaaat ctggcaattt cattaaagat atgccagatg taacgcatgt gcaaatcgga
    35041 gcaaccaagc gtgccaacaa tacggtttgg gggtcaaatc tacagattcg gaatctcact
    35101 gtgtataatc gtgctttaac accagaagag gtacaaaaac gtagtcaact ttttaaacgc
    35161 tcagatttag aaaaaaaact acctgaagga gcggctttaa cagagaaaac ggacatattc
    35221 gaaagcgggc gtaacggtaa accaaataaa gatggaatca agagttatcg tattccagca
    35281 cttctcaaga cagataaagg aactttgatc gcaggtgcag atgaacgccg tctccattcg
    35341 agtgactggg gtgatatcgg tatggtcatc agacgtagtg aagataatgg taaaacttgg
    35401 ggtaaccgag taaccattac caacttacgt gacaatccaa aagcttctga cccatcgatc
    35461 ggttcaccag tgaatatcga tatggtgttg gttcaagatc ctgaaaccaa acgaatcttt
    35521 tctatctatg acatgttccc agaagggaag ggaatctttg gaatgtcttc acaaaaagaa
    35581 gaagcctaca aaaaaatcga tggaaaaacc tatcaaatcc tctatcgtga aggagaaaag
    35641 ggagcttata ccattcgaga aaatggtact gtctatacac cagatggtaa ggcgacagac
    35701 tatcgcgttg ttgtagatcc tgttaaacca gcctatagcg acaagggtga tctatacaag
    35761 ggtaaccaat tactaggcaa tatctacttc acaacaaaca aaacttctcc atttagaatt
    35821 gccaaggata gctatctatg gatgtcctac agtgatgacg acgggaagac atggtcagcg
    35881 cctcaagata ttactccgat ggtcaaagcc gattggatga aattcttggg tgtaggtcct
    35941 ggaacaggaa ttgtacttcg gaatgggcct cacaagggac ggattttgat accggtttat
    36001 acgactaata atgtatctca cttaaatggc tcgcaatctt ctcgtgtcat ctattcagat
    36061 gatcatggaa aaacttggca tgctggagaa gcggtcaacg ataaccgtca ggtagacggt
    36121 caaaagatcc actcttctac gatgaacaat agacgtgcgc aaaatacaga atcaacggtg
    36181 gtacaactaa acaatggaga tgttaaactc tttatgcgtg gtttgactgg agatcttcag
    36241 gttgctacaa gtaaagacgg aggagtgact tgggagaagg atatcaaacg ttatccacag
    36301 gttaaagatg tctatgttca aatgtctgct atccatacga tgcataatgg aaaagaatac
    36361 attatcctca gcaatgcagg tggaccgaat cgtgaaaatg ggatggtcca cttggcacgt
    36421 gtcgaagaaa atggtgagtt gacttggctc aaacacaatc caattcaaaa aggagagttt
    36481 gcctataatt cgctccaaga attaggaaat ggggagtatg gcatcttgta tgaacatact
    36541 gaaaaaggac aaaatgccta taccctatca tttagaaaat ttaattggga atttttgagc
    36601 aaagatctga tttctcctac cgaagcgaaa gtgaagcgaa ctagagagat gggcaaagga
    36661 gagatgggca aaggagttat tggcttggag tttgactcag aagtattggt caacaaggct
    36721 ccaacccttc aattggcaaa tggtaaaaca gcgactttcc taacccagta tgatagcaaa
    36781 accttgttgt ttgcagtaga taaggaagat atcggacagg aaattattgg tatagctaaa
    36841 ggaagcatcg aaagtatgca taatcttcct gtaaatctag caggtgccag agttcctggc
    36901 ggagtaaatg gtagcaaagc agcggtgcat gaagttccag aatttacagg gggagttaat
    36961 ggtacagagc cagctgttca tgaaatcgca gagtataagg gatctgattc gcttgtaact
    37021 cttactacaa aagaagatta tacttacaaa gctcctcttg ctcagcaggc acttcctgaa
    37081 acaggaaaca aggagagtga cctcctagct tcactaggac taacagcttt cttccttggt
    37141 ctgtttacgc tagggaaaaa gagagaacaa taagagaaga attctaaaca tttgattttg
    37201 taaaaataga aggagatagc aggttttcaa gcctgctatc tttttttgat gacattcagg
    37261 ctgatacgaa atcataagag gtctgaaact actttcagag tagtctgttc tataaaatat
    37321 agtagattga aataagatgt gaacaactct atcaggaaag tcaaattaat ttatagaaaa
    37381 attttagcag tcaaggtgta ctgttataga ttcaatatat tatgtgacta ttaaccttct
    37441 cttctcctaa aattgacttt cttgttttct tatcttgtcc actcgaaaca agtattgtaa
    37501 gaatttgatt atttttgaaa gtacttttaa tatacttgat atagttaaaa aagatttgaa
    37561 actaaattcc aaattagaaa aagacttgaa atactaaaaa aaaaaagtat actctaattg
    37621 aaaacggtaa caaaactaat ttagagaatg aaatatagag tatttctctc ttaaaagttt
    37681 ttggtgaaac gagatgtaga aaggagattt agccaaagag tctattagtg ctagaataat
    37741 agattagaat tattttagaa aaacgaagtg agcagcttat aaattcaagt ccccaaatag
    37801 attcatacta gtatcttttg caaaaaataa agggcgactt ccttcatgaa tatcaatttc
    37861 atctataagg aaggtagcta attgaactaa cttatttatt ctgtttgtcg ctagaaaaat
    37921 cagacctcct tgtgaagatt gaggagatac tgaatgaaaa tcaaagaaga aactagcaag
    37981 ctagtagcag attgcccaaa acaccgcctt gaggttgtag ataagactga cctatataat
    38041 ccaaggtgaa gcgactgtgg tttgaagaga ttttcaaaga gtataggcta gagagtagtg
    38101 tttttatgtc cttctagtag aaaatgctag acagaagaat ggggaacttg gataggaaaa
    38161 atagattgag aaaggaggtt agaagagatg attattacaa aaattagcca tttaggaact
    38221 tatgtgggag taaatccaca ttttgcaaca ttaatagatt ttctagaaaa aacaggacta
    38281 gaaaatttaa cagaaggttc gattgctatc gatggtaatc gattgtttgg gaattgcttt
    38341 acttatctag cagatggtca agcaggggct ttctttgaaa cacaccaaaa atatttggat
    38401 attcatttag ttttggaaaa cgaagaagcc atggctgtta catcgccgga aaatgtaagc
    38461 gttacccaag aatatgatga agagaaagat attgaattat acacagggaa agtggaacag
    38521 ttggttcagt tgagagctgg cgaatgcctc atcacttttc cagaagattt acatcaaccc
    38581 aaggttcgta taaatgatga acctgtgaaa aaagttgtct ttaaagttgc gatttcttaa
    38641 tgtagaaaga gaagaacgat gaaaaaaatg agaaagtttt tatgtctagc tggaattgcg
    38701 ctagcggctg ttgccttggt agcttgttca ggaaaaaaag aagctacaac tagtactgaa
    38761 ccaccaacag aattatctgg tgagattaca atgtggcact cctttactca aggaccccgt
    38821 ttagaaagta ttcaaaaatc agcagatgct ttcatgcaaa agcatccaaa aacgaaaatc
    38881 aagattgaaa cattttcttg gaatgacttc tatactaaat ggactacagg tttagcaaat
    38941 ggaaatgtgc cagatatcag tacagctctt cctaaccaag taatggaaat ggtcaactca
    39001 gatgctttgg ttccgctaaa tgattctatc aagcgtattg gacaagataa atttaacgaa
    39061 actgccttaa atgaagcaaa aatcggagat gattactact ctgttcctct ttattcacat
    39121 gcacaagtca tgtgggttag aacagatttg ttaaaagaac ataatattga ggttcctaaa
    39181 acttgggatc aactctatga agcttctaaa aaattgaaag aagctggagt ttatggcttg
    39241 tctgttccgt ttggaacaaa tgacttaatg gcaacacgtt tcttgaactt ctacgtacgt
    39301 agtggtggag gaagcctctt aacaaaagat cttaaagcag acttgacaag ccaacttgct
    39361 caagatggta ttaaatactg ggttaaattg tataaagaaa tctcacctca agattctttg
    39421 aactttaatg tccttcaaca agctaccttg ttctatcaag gaaaaacagc atttgacttt
    39481 aactctggct tccatatcgg aggaattaat gccaacagtc ctcaattgat tgattcgatt
    39541 gatgcttatc ctattccaaa aatcaaagag tctgataaag accaaggaat tgaaacctca
    39601 aacattccaa tggttgtttg gaaaaattca aaacatccag aagttgctaa agcattctta
    39661 gaagcacttt ataatgaaga agactacgtt aaattccttg attcaactcc agtaggtatg
    39721 ttgccaacta ttaaggggat tagcgattct gcagcctata aagaaaatga aactcgtaag
    39781 aagtttaaac atgctgaaga agtaattact gaagctgtta aaaaaggtac tgctattggt
    39841 tatgaaaatg gaccaagtgt acaagctggt atgttgacta accaacacat tattgaacaa
    39901 atgttccaag atatcattac aaatggaaca gatcctatga aagcagcaaa agaagcagaa
    39961 aaacaattaa acgatttatt tgaggctgtt cagtagatgt aaaagactag aaaataggtg
    40021 ggctagtgag ctgaaaagct ctagcccaat cttgtaaaag aagggagaag gagaatggtt
    40081 aaagaacgta atttaactcg ctggatattt gttttgccag ctatgattat cgtaggatta
    40141 ctctttgttt atccgttttt ctcgagtatt ttttatagct ttaccaataa gcatttgatt
    40201 atgcctaatt ataaatttgt tggtttggct aactataaag ctgtgctatc agatcccaac
    40261 ttctttaatg cgttctttaa ttcaattaag tggaccgttt tctcattagt tggtcaagtt
    40321 ttagtagggt ttgtattggc tttagctctt cacagagtac gccacttcaa gaaattatat
    40381 aggaccttat tgattgttcc ttgggcattt cctaccatcg ttattgcctt ttcttggcag
    40441 tggattctaa acggggttta tggctactta cctaatctaa tcgtaaaatt aggtttaatg
    40501 gaacatacac ctgcattttt gacagatagt acatgggcat tcctatgttt ggtgtttatc
    40561 aacatttggt ttggagcacc aatgattatg gttaatgtgc tttcagcttt gcaaacagta
    40621 ccagaagaac aatttgaggc tgctaagata gatggtgctt caagttggca ggtgttcaag
    40681 tttatcgtct ttccacatat taaagtggtt gtaggacttc tagttgtttt gagaactgta
    40741 tggatcttta ataactttga cattatctac ctcattactg gtggtggacc agccaatgct
    40801 acaacgacgc ttccaatttt tgcttacaac ctgggctggg gaactaaatt gttgggtcgt
    40861 gcttcagcag ttacagtatt gctctttatc ttcttggtgg cgatttgctt tatctacttt
    40921 gctatcatca gtaagtggga aaaggagggt agaaaataat gaagaagaaa tccagtattt
    40981 atttagatat tctctcacat gtacttttag ttggtgcgac catcgttgca attttcccat
    41041 tggtatggat tatcatatct tctgtcaaag ggaaagggga attaactcag tatccaacac
    41101 gattttggcc tgaacagttt acattagatt atttcactca tgttatcaac gatttgcact
    41161 tcattgataa cattcgaaac agtttaatca ttgccttggc tacaaccctc attgcgatta
    41221 ttatttctgc tatggcagcc tatggtattg ttcgattctt tcctaaattg ggagcaatca
    41281 tgtcgagact actcgtcatt acctacattt tcccaccaat tttgttagca attccctatt
    41341 caattgccat tgctaaagtt gggttaacaa atagtttatt tggcttgatg atggtttatc
    41401 tatcttttag tgttccatat gcagtttggc tcttagttgg atttttccaa acagttccaa
    41461 ttggaattga agaagcggct agaattgatg gtgcaaataa atttgttacg ttttataaag
    41521 ttgtgctacc gattgtagca ccaggtattg tagcaacagc tatttataca tttatcaatg
    41581 cttggaatga attcctgtat gccttgattt tgattaacaa tacaggaaag atgacagtag
    41641 cagtagccct tcgttcactt aatggttcag aaatactaga ctggggagat atgatggcag
    41701 cgtctgttat tgtagttctt ccatcaatta ttttcttctc tatcatccaa aataagattg
    41761 caagtggatt atcagaagga tctgtgaagt agacgaaaga aggaaaaaaa tgaataaaag
    41821 aggtctttat tcaaaactag gaatttctgt tgtaggcatt agtcttttaa tgggagtccc
    41881 cactttgatt catgcgaatg aattaaacta tggtcaactg tccatatctc ctatttttca
    41941 aggaggctca tatcaactga acaataagag tatagatatc agccctttgt tattagataa
    42001 attgtctgga gagagtcaga cagtagtaat gaaatttaaa gcagatgaac caaactctct
    42061 tcaagctttg tttggcctat ctaatagtaa agcaggcttt aaaaataatt acttttcaat
    42121 tttcatgaga gattctggtg agataggtgt agaaataaga gacgcccaaa agggaataaa
    42181 ttatttattt tccagaccag cttcattatg gggaaaacat aaaggacagg cagttgaaaa
    42241 tacactagta tttgtatctg attctaaaga taaaacatac acaatgtatg ttaatggaat
    42301 agaagtgttc tctgaaacag ttgatacatt tttgccaatt tcaaatataa atggtataga
    42361 taaggcaaca ctaggagctg ttaatcgtga aggcaaggaa cattacctcg caaaaagaag
    42421 tattgatgaa atcagtctat ttaacaaagc aattagtgat caggaagttt caaatattcc
    42481 cttgtcaaat ccatttcagt taattttcca atcaggagat tctactcaag ctaactattt
    42541 tagaataccg acactatata cattaagtag tggaagagtt ctatcaagta ttgatgcacg
    42601 ttatggtggg actcatgatt ctaaaagtaa gattaatatt gccacttctt atagtgatga
    42661 taatgggaaa acgtggagtg agccaatttt tgctatgaag tttaatgact atgaggagca
    42721 gttagtttac tggccacgag ataataaatt aaagaatagt caaattagtg gaagtgcttc
    42781 attcatagat tcatccattg ttgaagataa aaaatctggg aaaacgatat tactagctga
    42841 tgttatgcct gcgggtattg gaaataataa tgcaaataaa gccgactcag gttttaaaga
    42901 aataaatggt cattattatt taaaactaaa gaagaatgga gataacgatt tccgttatac
    42961 agttagagaa aatggtgtcg tttatgatga aacaactaat aaacctacaa attatactat
    43021 aaatgataag tatgaagttt tggagggagg aaagtcttta acagtcgaac aatattcggt
    43081 tgattttgat agtggctctt taagagaaag gcataatgga aaacaggttc ctatgaatgt
    43141 tttctacaaa gattcgttat ttaaagtgac tcctactaat tatatagcaa tgacaactag
    43201 tcagaataga gaagagagtt gggaacaatt taagttgttg cctccgttct taggagaaaa
    43261 acataatgga acttacttgt gtcctggaca aggtttagca ttaaaatcaa gtaacagatt
    43321 gatttttgca acatatacta gtggagaact aacctatctc atttctgatg atagtggtca
    43381 aacatggaag aaatcctcag cttcaattcc gtttaaaaat gcaacagcag aagcacaaat
    43441 ggttgaactg agagatggtg tgattagaac attctttaga accactacag gtaagatagc
    43501 ttatatgact agtagagatt ctggagaaac atggtcggaa gtttcgtata ttgatggaat
    43561 ccaacaaact tcatatggca cacaagtatc tgcaattaaa tactctcaat taattgatgg
    43621 aaaagaagca gtcattttga gtacaccaaa ttctagaagt ggccgtaagg gaggtcaatt
    43681 agttgtcggt ttagtcaata aagaagatga tagtattgat tggaaatacc actatgatat
    43741 tgatttgcct tcgtatggtt atgcctattc tgcgattaca gaattgccaa atcatcacat
    43801 aggtgtactg tttgaaaaat atgattcgtg gtcgagaaat gaattgcatt taagcaatgt
    43861 agttcagtat atagatttgg aaattaatga tttaacaaaa taaaggagaa aaacatggtt
    43921 aaatacggtg ttgttggagc agggtatttt ggagctgaat tggctcgcta catgcaaaag
    43981 aatgatggag cagagattac tcttctctat gatccagata atgcagaggc gattgcagaa
    44041 gaattgggag caaaagtagc aagttcctta gatgagttgg tttctagcga tgaagtagat
    44101 tgtgttatcg tcgcaactcc aaataatctt cataaggaac cggttattaa ggctgcacag
    44161 catggtaaaa atgttttctg tgaaaaacca attgcgcttt cttatcaaga ttgtcgcgag
    44221 atggtagatg cgtgtaaaga aaacaatgta acctttatgg caggacatat tatgaatttc
    44281 tttaatggtg ttcatcatgc aaaagaactc attaatcaag gagttatcgg agacgttcta
    44341 tattgtcata cagctcgtaa tggttgggaa gaacaacaac cgtcagtgtc atggaaaaaa
    44401 attcgtgaaa aatcaggtgg tcacttgtat caccacatcc atgaattgga ttgcgttcaa
    44461 ttccttatgg ggggcatgcc tgaaactgta accatgacag gtggaaatgt ggcccatgaa
    44521 ggtgaacatt tcggtgatga agatgatatg atttttgtca atatggaatt ttctaataag
    44581 cgttttgcct tgttagaatg gggttcagct tatcgttggg gtgaacatta tgtcttaatc
    44641 caaggaagca aaggtgccat ccgcttagac ttattcaact gtaaaggaac tcttaagcta
    44701 gatgggcaag aaagctattt cttgattcac gaatcgcaag aagaagatga tgatcggact
    44761 cgtatctatc atagtacaga gatggatgga gcaattgctt atggtaaacc aggtaaacgt
    44821 actccattat ggctatcatc tgtcattgat aaagaaatgc gctatctgca tgagattatg
    44881 gaaggagctc cagtatcaga agaatttgca aaacttttga caggtgaagc tgccctagaa
    44941 gcaattgcta ctgcagatgc ttgtacccag tctatgtttg aagatcgcaa agtaaaattg
    45001 tcagaaattg taaaataaat tttggtattc tcctatttat aggtcgactt gctcctctga
    45061 aagtactttt agaggagctg tttgactttg ctagtttttg aaactgaaat ctattatact
    45121 acaaactatt gaaagcgttt taattttaag gtataataat ctcatagaaa taaagaaaag
    45181 gaggaaagag gatgccacag attagcaaag aagccttgat tgagcaaatc aaagatggaa
    45241 tcatcgtttc ttgtcaggct cttcctcatg aaccgcttta tacagaagcg ggaggggtga
    45301 ttcccttgct ggtcaaagcg gctgagcaag gtggagcagt cggtatccga gcaaacagtg
    45361 ttcgcgatat caaggaaatt aaggaagtca ctaaacttcc aatcattggg attatcaaac
    45421 gtgattatcc acctcaggaa cccttcatca cggctactat gaaagaagtt gatgaattgg
    45481 cagaactgga catcgaggtg attgctctgg attgtaccaa gcgtgaacgc tacgatggtt
    45541 tggaaattca agagttcatt cgtcaggtta aggagaaata tcctaatcag cttttgatgg
    45601 ctgatactag tatcttcgaa gaagggctag cagctgtaga agcaggaatt gactttgtcg
    45661 gaacaacctt atcaggctac acatcctaca gtccaaaagt agacggtcca gattttgaat
    45721 tgattaagaa actctgtgat gccggtgtag atgtcattgc agaaggaaaa attcatacac
    45781 cagaacaagc caaacaaatc cttgaatatg gagtgcgagg catcgttgtt ggtggcgcca
    45841 ttactagacc aaaagagatt acagaacgct tcgttgctag tcttaaataa gatgtgaggg
    45901 ggagttttat gtttaaagtt ttacaaaaag ttggaaaagc ttttatgtta cctatagcta
    45961 tacttcctgc agcaggtcta cttttgggga ttggtggtgc actttcaaac ccaaccacga
    46021 tagcaactta tccaatacta gacaatagta tttttcaatc aatattccaa gtaatgagct
    46081 ctgcaggaga ggttgtattc agtaatttgt cactacttct ctgtgtggga ttatgtattg
    46141 gcttagcgaa acgagataaa ggaaccgctg cgttagcagg agtaactggt tacttagtta
    46201 tgactgcaac gatcaaagct ttagtaaaac tttttatggc agaaggatct gcaattgata
    46261 ctggagttat tggagcatta gttgtcggaa tagttgccgt atatttgcac aaccgatata
    46321 acaatattca attaccttcc gctttaggat tctttggagg ttcacgcttc gttcctattg
    46381 ttacatcgtt ctcttctatc ttgattggct ttgtcttctt tgttatttgg ccacctttcc
    46441 aacaacttct tgtttctaca ggtggatata tttctcaggc gggtccaatt ggaacttttc
    46501 tatatggatt tttaatgaga ctttctggag cagtaggctt acatcatata atttacccta
    46561 tgttttggta tactgaactt ggtggtgttg aaactgttgc aggacaaaca gtggttggag
    46621 ctcaaaaaat attttttgct caattagccg atttggccca ttctggatta tttacagaag
    46681 gaacaaggtt ttttgcaggt cgtttctcaa caatgatgtt cggtttaccg gctgcctgtt
    46741 tagcgatgta ccatagtgtt cctaaaaatc gtcgtaaaaa atacgcgggt ttgtttttgg
    46801 gagttgcttt aacatctttt attaccggta ttacagaacc aattgaattt atgtttctat
    46861 tcgttagtcc ggttctatat gttgttcacg cattccttga tggtgttagc ttctttattg
    46921 cagacgtctt aaatatttca ataggaaaca cattttcagg aggtgtaatc gatttcactt
    46981 tatttggaat tttgcagggg aacgctaaga cgaattgggt tcttcagatt ccatttggac
    47041 ttatttggag tgttttgtat tatattattt ttagatggtt cattactcaa ttcaacgttc
    47101 taacgccagg gcgaggagaa gaagtagatt ctaaagaaat ttctgaatcc gcagattcaa
    47161 cttcaaatac tgcagattat ttaaaacagg atagcctaca aattatcaga gccttgggtg
    47221 gatcaaataa tatagaagat gtagatgctt gtgtgacacg tttacgtgta gctgtaaaag
    47281 aagttaatca agttgataaa gcacttttaa aacaaattgg tgcagttgat gtcttagaag
    47341 tgaagggtgg cattcaagca atatatggag caaaagcaat cttatataaa aatagtatta
    47401 atgaaatttt aggtgtagat gattaagtac ttactgactt aataaaaaac agaggagagt
    47461 gatggatgag taggatgaaa tgaaatcgca tacaagaaat aaagaactca ttatccaagt
    47521 tggatacgct tattacatag gagaatacaa atgaaattta gaaaattagc ttgtacagta
    47581 cttgcgggtg ctgcggttct tggtcttgct gcttgtggca attctggcgg aagtaaagat
    47641 gctgccaaat caggtggtga cggtgccaaa acagaaatca cttggtgggc attcccagta
    47701 tttacccaag aaaaaactgg tgacggtgtt ggaacttatg aaaaatcaat catcgaagcg
    47761 tttgaaaaag caaacccaga tataaaagtg aaattggaaa ccatcgactt caagtcaggt
    47821 cctgaaaaaa tcacaacagc catcgaagca ggaacagctc cagacgtact ctttgatgca
    47881 ccaggacgta tcatccaata cggtaaaaac ggtaaattgg ctgagttgaa cgacctcttc
    47941 acagatgaat ttgttaaaga tgtcaacaat gaaaacatcg tacaagcaag taaagctgga
    48001 gacaaggctt atatgtatcc gattagttct gccccattct acatggcaat gaacaagaaa
    48061 atgttagaag atgctggagt agcaaacctt gtaaaagaag gttggacaac tgatgatttt
    48121 gaaaaagtat tgaaagcact taaagacaag ggttacacac caggttcatt gttcagttct
    48181 ggtcaagggg gagaccaagg aacacgtgcc tttatctcta acctttatag cggttctgta
    48241 acagatgaaa aagttagcaa atatacaact gatgatccta aattcgtcaa aggtcttgaa
    48301 aaagcaacta gctggattaa agacaatttg atcaataatg gttcacaatt tgacggtggg
    48361 gcagatatcc aaaactttgc caacggtcaa acatcttaca caatcctttg ggcaccagct
    48421 caaaatggta tccaagctaa acttttagaa gcaagtaagg tagaagtggt agaagtacca
    48481 ttcccatcag acgaaggtaa gccagctctt gaataccttg taaacggatt tgcagtattc
    48541 aacaataaag acgacaagaa agtcgctgca tctaagaaat tcatccagtt tatcgcagat
    48601 gacaaagagt ggggacctaa agacgtagtt cgtacaggtg ctttcccagt ccgtacttca
    48661 tttggaaaac tttatgaaga caaacgcatg gaaacaatca gcggctggac tcaatactac
    48721 tcaccatact acaacactat tgatggtttt gctgaaatga gaacactttg gttcccaatg
    48781 ttgcaatctg tatcaaatgg tgacgaaaaa ccagcggatg ctttgaaagc cttcactgaa
    48841 aaagcaaacg aaacaatcaa aaaagctatg aaacaatagt ccttagttat tctataaaaa
    48901 gtagtttttt aaagaaccta agagtgtata cccccttttc cctctacaca gatagtgtaa
    48961 gaaaaggggg cttttgttta aaatgtaaga aactgtcacg aaattaaaat gaagttctta
    49021 cataagcgaa tcataaaaaa tttcattttg attttaaaac agttcaagaa agtcaaaaaa
    49081 ttattctatt tgaaagagag gtgccgactg tgaaagtcaa taaaatccgt atgcgggaaa
    49141 cagtgatttc ctacgctttc ctagcaccag tattattctt ctttgtcatc tttgtgttgg
    49201 ctccgatggt gatgggcttc attacaagtt tctttaacta ctcaatgact aaatttgagt
    49261 ttgtaggctt ggataactat atccgtatgt ttaaagatcc tgtctttaca aaatctctga
    49321 ttaacacagt tattttggtt attggatctg taccagttgt tgttctattc tcactctttg
    49381 tagcatctca gacctatcat caaaatgtca ttgccagatc cttctaccgt ttcgtcttct
    49441 tccttcctgt tgtaacgggt agtgttgccg tgacagttgt ttggaaatgg atttatgacc
    49501 cactatcagg gattctaaac tttgtcctta agtccagcca catcatcagc caaaacattt
    49561 cttggttggg agataaaaac tgggcattga tggcgattat gattattctc ttgaccactt
    49621 cagttggtca gcccatcatc ctttatatcg ctgccatggg gaatattgac aattcactgg
    49681 ttgaagcggc gcgtgttgat ggtgcaactg agtttcaagt tttttggaag attaaatggc
    49741 caagccttct tccaacaact ctttatattg caatcatcac aacaattaac tcattccagt
    49801 gtttcgcctt gattcagctt ttgacatctg gtggtccaaa ctactcaaca agtaccttga
    49861 tgtactacct ttacgaaaaa gccttccaat tgacagaata cggctatgcc aacacaattg
    49921 gtgtcttctt ggcagtcatg attgctatcg taagctttgt tcaatttaaa gtacttggaa
    49981 acgacgtaga atactaaaga aaggagacag ctatgcaatc tacagaaaaa aaaccattaa
    50041 cagcctttac tgttatttca acaatcattt tgctcttgtt gactgtgctg ttcatctttc
    50101 cattctactg gattttgaca ggggcattca aatcacaacc tgatacaatt gttattcctc
    50161 ctcagtggtt ccctaaaatg ccaaccatgg aaaacttcca acaactcatg gtgcagaacc
    50221 ctgccttgca atggatgtgg aactcagtat ttatctcatt ggtaaccatg ttcttagttt
    50281 gtgcaacctc atctctagca ggttatgtat tggctaaaaa acgtttctat ggtcaacgca
    50341 ttctatttgc tatctttatc gctgctatgg cgcttccaaa acaagttgtc cttgtaccat
    50401 tggtacgtat cgtcaacttc atgggaatcc acgatactct ctgggcagtt atcttgcctt
    50461 tgattggatg gccattcggt gtcttcctca tgaaacaatt tagtgaaaat attcctacag
    50521 agttgcttga atcagctaaa atcgacggtt gtggtgagat tcgtaccttc tggagtgtag
    50581 ccttcccgat tgtgaaacca gggtttgcag cccttgcaat ctttaccttc atcaatactt
    50641 ggaatgacta cttcatgcag ttggtaatgt tgacttcacg taacaatttg accatctcac
    50701 ttggggttgc gaccatgcag gctgaaatgg caaccaacta tggtttgatt atggcaggag
    50761 ctgcccttgc tgctgttcca atcgtcacag tcttccttgt cttccaaaaa tccttcacac
    50821 agggtattac tatgggagcg gtcaaaggat aatactctgc gaaaatcgaa tgcaaactac
    50881 gtcagcttca ccttgccata cttaagtatt gcctgcggtt agcttcctag tttgttcttc
    50941 aattttcatt gagtatagga aaatcaatct atcaagatac agaagtatat tttatagatt
    51001 tagagaatat agaagttata agtgtctaca aaatggaggg tatgcagtta ctttatgaag
    51061 ttttgtcaga cacttatcaa cttaagaatg attttagtta attatcagaa acgaaggaaa
    51121 gagtatgatt tttgacgatt tgaaaaacat caccttttac aaagggattc atcccaattt
    51181 agacaaagct atcgactacc tctaccaaca tcgtaaagat tcattcgaat taggaaagta
    51241 tgagattgat ggagataagg tctttctagt tgttcaggaa aatgtcctca atcaagttga
    51301 gaataatcaa tttgaacacc ataagaacta tgcagatttg catttgctga tagaagggca
    51361 tgaatattcg agctacggtt cacgtatcaa agacgaggca gtagcattcg acgaagcgac
    51421 tgacattggc tttgttcatt gtcatgaaca ctacccactc ttgttgggtt atcataattt
    51481 tgcgattttc ttcccaggtg agccacatca gccaactggc tatgcaggta tggaagaaaa
    51541 ggttcgaaaa tatctcttta aaattttgat tgattaaaaa taggatgaat tgtttttttg
    51601 taaagctttg acaatactct accatgaaat tgatctttat gaggtagaga aatgagaata
    51661 aaatatttaa aaattggtat cttctaagca tgctgcaaga gctagtttct tagatggaca
    51721 ggaaattaca gttgatgaga tgtcctggat aattaatggc attgtgaatg cattgattgg
    51781 tagatacata aaattaggta cttatgcagc taagtatggt attggtatag cacgctcgat
    51841 cttaagtagg gcagctgcaa ctgcagcagc aagagtagga ttactgacca agatttctgg
    51901 atggatttta cgagtagctg tgaatgtagc tgatgtatat ggtaatttcg ccaacaatat
    51961 tgctgcagct tgggatgcat atgataaaat tcctaacaat ggtcgtataa acttttaaaa
    52021 tacgagaatg aaagcacttt gtattttttt attgaatatg ttagcttgga cagtgcttgc
    52081 aatgataatt cgtggagggc tagatggatt tgataggcat acttggagta ctattttaat
    52141 tgcttcgctg ttcggggtat atgattataa gcccatagat aaaaatagaa aaaagtccaa
    52201 aagaaaaaag aaaaaataga tttgttcatg gtagggactt atgaaagctt tactgacaaa
    52261 aaagaaaaca gtttacaaag aaaaatgatg gaggagcaaa catggcacaa aaaggagtaa
    52321 gccttatcaa ggcagcattt gatacagata actttctcat gcgttttagt gagaaggtct
    52381 tggacatcgt gacagccaat cttctttttg tcgtctcttg tttacccatc gtgacgattg
    52441 gagtggctaa aatcagcctc tacgagacca tgttcgaagt taagaagagc agacgggtgc
    52501 ctgtttttaa aatctatcta agatctttca agcaaaatct gaaactaggt cttcagctgg
    52561 gtttaatgga gttaggaatt gtgtttctta ccctttcaga tctctatctt ttctggggtc
    52621 aaacagctct gcccttccaa ttgctgaaag ccatttgttt aggtattctg atttttctta
    52681 ctatcgtgat gctggctagt taccctatcg cggcacgtta tgacctatct tggaaagaaa
    52741 ttcttcaaaa aggattgatg ttggctagtt ttaactttcc ttggttcttc ctcatgttag
    52801 ccattcttgt cctcattgtg atggttcttt atctgtccgc cttcagtcta ctcttaggtg
    52861 gctcagtctt cctacttttt gggtttggac tattggtctt tatccagact ggattgatgg
    52921 agaaaatttt cgcaaaatac caataggagc tttatttctg aaactacttt caaaggctcc
    52981 aaacgctatt ctataagcga gaaactaaaa tctaagtgtc tataagatat tgaaagcctt
    53041 ttcggtaaag tgtatactaa agaagtaaag aaaaatctgc tttagcagaa aataaaaata
    53101 ataggagaaa atctatgtca gatttgaaaa aatacgaagg tgtcattcca gccttctacg
    53161 catgttatga tgagcaagga gaagtaagtc cagagcgtac gcgtgccttg gttcaatact
    53221 tcattgataa aggtgttcaa ggtctttatg tcaatggttc ttctggtgaa tgtatctacc
    53281 aaagcgttga agatcgcaag ttgattttgg aagaagtcat ggcggtagct aaaggtaaat
    53341 tgaccattat tgcccatgtt gcctgcaaca atactaaaga cagtatggaa cttgctcgcc
    53401 atgctgaaag cttgggagta gatgctattg caacgattcc accaatttat ttccgcttgc
    53461 cagaatactc agttgccaaa tactggaacg atatcagttc tgcagctcca aacacagact
    53521 acgtgattta caacattcct caattggcag gggttgcttt gactccaagc ctttacacag
    53581 aaatgttgaa aaatcctcgt gttatcggtg tgaagaactc ttctatgcca gttcaagata
    53641 tccaaacctt tgtcagcctt ggtggggaag accatatcgt ctttaacggt ccagatgaac
    53701 agttcctagg tggtcgcctc atgggtgcca aagctggtat cggtggtact tatggtgcta
    53761 tgccagaact cttcttgaaa ctcaaccaat tgattgcgga taaagattta gaaacagcgc
    53821 gtgagttaca gtatgctatc aacgctatca ttggtaaatt gactgctaca catggaaata
    53881 tgtacggtgt catcaaagaa gttttgaaga tcaatgaagg cttgaatatt ggttctgttc
    53941 gttcaccatt gacaccagtg actgaagaag atcgtccagt tgtagaagcg gctgctgcct
    54001 tgattcgtga aaccaaggag agcttcctct aatctaaaag gaggtattta tgacatacta
    54061 cgttgcaatt gatatcggtg gaaccaacat caagtatggt ttggttgatc aagaggggca
    54121 acttcttgaa tcgcatgaaa tgccaactga ggcgcataag ggtggacctc atatcttaca
    54181 aaagaccaaa gatatcgtag ctagttattt agaaaaaggc ccagtagcag gtgttgccat
    54241 atcttctgct gggatggtgg atccggataa gggtgagatt ttctatgctg ggccgcaaat
    54301 ccctaactac gcaggcaccc agttcaaaaa ggaaatcgaa gaaagcttta ctattccttg
    54361 tgagattgaa aatgatgtca actgtgcagg tcttgctgag gcagtatctg gttcaggcaa
    54421 gggagcaagt gtgacacttt gcttgaccat tggaaccggt atcggtggtt gcttgattat
    54481 ggataggaaa gtcttccatg gttttagcaa ttcagcctgt gaagtcgggt atatgcatat
    54541 gcaggatgga gcttttcaag acttggcttc tacaacagct ttagtgaaat atgtagctga
    54601 agcccatgga gaagatgttg atcagtggaa tggccgtaga attttcaaag aagccactga
    54661 aggaaacaaa atctgcatgg aaggtattga ccgtatggtt gactatctag gaaaaggtct
    54721 ggcaaatatt tgctacgttg ccaatccaga agtggttatt cttggtggtg gtatcatggg
    54781 gcaagaggct atcctcaaac ctaagatccg cacagccttg aaagaggctt tggtaccaag
    54841 tttagcagaa aaaacacgat tagaatttgc ccatcaccaa aatacagcag ggatgttggg
    54901 tgcatattat cattttaaga caaaacaatc ctagtttggc tcagccaaac taggattttc
    54961 ttacacgttt ttgtctacga tagccgttga gttttttatt ttcccagtag ctattaaaga
    55021 ttttttcctt gctttcgcga ttgatttcca aaaagtaggc ataaatcaaa tcgataaaga
    55081 agagcatagg aagttgagcg gatattcgtt ggatatagga gggttggctg tgggtggcta
    55141 caagaacagt ctctgtatag gtctggctat ctttattggg aacacttgta aagagtacag
    55201 tctttgcccc catctccttg gcatctaata gactatctaa aatagaagga gttgagcctg
    55261 aaagtgagaa gcccagtact agacaatttt catccatgat gctggttgtc caggcaaagc
    55321 cgtcttggtc tgtcaaagct tcgcagacca cacctagtcg cataaaacgt aatttcattt
    55381 cacgggcgac gaggccagaa ctccctgttc caaagaagta gatacgctca gcatcttcga
    55441 ttagctgggc aattcgctct agttggattt cgtcaatcaa gtcttgtgtt tgttccctca
    55501 tattgctata acttctgagg actcgtttgg tcagtggact gtgcttggag actcggttgg
    55561 cttgattttc tgcctgatgt tggtattgga aaataaattc tcggtagcca gtaaagccac
    55621 actttttagc aaagcgggtc aaagcagctt gagaaatatg taatttttgg gtgacttgtt
    55681 gagaagataa atcatctgta atcgtttcag cttgcaaaaa atagcgagcg atttcttgct
    55741 ctaggtctgt catttcttca aaatgtgaat caatgatagt tgcgatatct ggtttgtcca
    55801 tagggaaagc tcctttacat gagtcatact ggaagactag atcagggaat agtcacactt
    55861 cattataaca cataatataa ggatagataa ataaaaacgc atctctgttt taaaaacgaa
    55921 aaaatcgaaa aagcttctct cttttccata attttctact caaattgtgg tacaattaag
    55981 agtaagattt taagttagaa atgagactga tttgtatgag aaaatttaac agccattcga
    56041 ttccgattcg gcttaattta ttgttttcaa tcgtcatttt actctttatg accattattg
    56101 gtcgtttgtt gtatatgcag gttttgaaca aggattttta cgaaaaaaag ctagcctcag
    56161 ctagtcagac caagattaca agcagttcag cccgtgggga aatttatgat gctagtggaa
    56221 aacctttggt agaaaatacg ttaaagcagg ttgtttcctt tacgcgtagc aataaaatga
    56281 cggctacaga cttaaaagaa acagctaaaa agttactgac ttatgtgagc atcagttctc
    56341 caaatttgac aaaacgccag ctggcggatt actatttggc tgatcctgaa atctataaaa
    56401 aaacagtgga agctctccca agcgagaaac gcttggattc agatggcaat cgtctatccg
    56461 aatcagaact gtataacaat gcggtcgata gtgtccaaac aagtcaacta aactatacag
    56521 aggatgaaaa gaaagaaatc tatcttttta gtcagttaaa tgctgttgga aactttgcga
    56581 caggaaccat tgctacagat cctctaaatg attctcaggt ggctgttatt gcctctattt
    56641 caaaggagat gcctggcatt agtatttcta cttcttggga tagaaaggtt ttggaaactt
    56701 ccctttcttc tatagttggg agtgtatcca gtgaaaaagc tggtctccca gcggaagaag
    56761 cagaagccta tcttaaaaaa ggctattctc taaatgaccg tgtaggaacc tcctatttgg
    56821 aaaagcaata tgaagagacc ttacaaggaa aacgatcggt aaaagaaatc catctggata
    56881 aatatggcaa tatggaaagc gtggatacaa ttgaggaagg tagtaaggga aacaatatca
    56941 aactgaccat tgatttggcc ttccaagata gcgtggatgc tttgctgaaa agttatttca
    57001 attctgagct agaaaatggt ggagccaagt attctgaagg tgtctatgca gtcgccctta
    57061 acccaaaaac aggtgcggtt ttgtctatgt cagggattaa acatgacttg aaaacgggag
    57121 agttgacgcc tgattccttg ggaacggtaa ccaatgtctt tgttccaggt tcggttgtca
    57181 aggcggcgac catcagctca ggttgggaaa atggagtctt gtcaggaaac cagaccttga
    57241 cagaccagtc cattgtcttc caaggttcag ctcccatcaa ttcttggtat actcaggctt
    57301 acggttcatt ccctatcaca gcggtccaag ctctggagta ttcatcaaat acctatatgg
    57361 tccaaacagc cttaggtctt atggggcaaa cctatcaacc caatatgttt gtcggcacca
    57421 gcaatctaga gtctgctatg gagaaactgc gttcaacctt tggcgaatat ggcttgggta
    57481 ctgcgacagg aattgaccta ccagatgaat ctactggatt tgttcccaaa gagtatagct
    57541 ttgctaatta cattactaat gcctttgggc agtttgataa ctatacgccg atgcagttgg
    57601 ctcagtatgt agcaactatt gcaaataatg gtgttcgtgt ggctcctcgt attgttgaag
    57661 gcatttatgg taataatgat aagggaggac tgggtgactt gattcagcaa ctgcaaccga
    57721 cagagataaa taaggtcaat atatccgact ccgatatgag catcttgcac caaggttttt
    57781 atcaggttgc ccatggtact agtggattga caactggacg tgccttttca aatggtgcct
    57841 tggtatccat tagcggaaaa acaggtacag ccgaaagcta tgtggcagat ggtcagcaag
    57901 caaccaatac caatgcggtg gcctatgccc catctgataa tccccaaatc gctgtcgcag
    57961 tggtctttcc tcataatacc aatctaacaa atggtgtagg accttccatt gcgcgtgaca
    58021 ttatcaatct gtatcaaaaa taccatccaa tgaactagaa aggaaattat gctttatcca
    58081 acacctattg ccaagttgat tgacagttat tctaagttac caggtatcgg gattaagacg
    58141 gctacgcgtc tggcctttta tacgattggg atgtctgctg atgatgtcaa tgaatttgca
    58201 aaaaatctcc tttctgctaa gagagaattg acatattgtt ctatttgtgg acgtttgaca
    58261 gacgacgatc cttgttctat ctgtactgat ccgactcgtg accagacaac aattttagtt
    58321 cttgaggata gtagagatgt ggcagccatg gaaaatatcc aagaatacca tggactctat
    58381 catgtcctgc atggcctcat ttctcctatg aatggtatca gtccggacga tatcaatctc
    58441 aagagcctta tgactcgtct tatggatagt gaggtttcag aagtgattgt ggcgactaat
    58501 gctacagcgg atggtgaagc gacttccatg tatctttcac gtttgctcaa gccagctggt
    58561 atcaaggtta cgcgtctagc acgaggtctc gctgtgggag cggacattga gtatgcggac
    58621 gaagtgacac tcttacgagc gattgaaaat cggacagagt tgtaagtgta ggcaaattta
    58681 cgaactccct tcatttataa aaaatcaaag aggctgaaaa tcgttcctat cggcctcttt
    58741 ttgtatagtg tgatgagtag gatcgggttc aagttttaaa aaaccaagca aatatgatat
    58801 actaaagagc gagtattcta gtagaattag gacaaataat atgaaacaaa cgattattct
    58861 tttatatggt ggacggagtg cggaacgcga agtctctgtc ctttcagctg agagtgtcat
    58921 gcgtgcggtc aattacgacc gtttcacagt caagactttc tttatcagtc agtcaggtga
    58981 ctttatcaaa acacaggaat ttagtcatgc tccggggcaa gaagaccgtc tcatgaccaa
    59041 tgaaaccatt gattgggata agaaagttgc accaagtgct atctacgaag aaggtgcagt
    59101 ggtctttcca gtccttcacg ggccaatggg agaagatggc tctgttcaag gattcttgga
    59161 agttttgaaa atgccttacg ttggttgcaa cattttgtca tcaagtcttg ccatggataa
    59221 aatcacgact aagcgtgttc tggaatctgc tggtattgcc caagttcctt atgtggctat
    59281 cgttgaaggc gatgatgtga ctgctaaaat cgctgaagtg gaagaaaaat tggcttatcc
    59341 agtcttcact aagccgtcaa acatggggtc tagtgtcggt atttctaagt ctgaaaacca
    59401 agaagaactc cgtcaagcct taaaacttgc cttccgatat gacagccgtg tcttggttga
    59461 gcaaggagtg aatgcccgtg aaattgaggt tggcctcttg ggtaactacg atgtcaagag
    59521 cacgctacct ggagaagttg tcaaggacgt tgccttttat gactacgatg ccaagtatat
    59581 tgataacaag attactatgg atattcctgc caaaatcagt gatgatgtgg tagctgtcat
    59641 gcgtcaaaat gcagaaacag ccttccgtgc cattggtggc cttggtctat ctcgttgcga
    59701 tttcttctat acagataagg gagagatttt tctcaacgag ctcaatacca tgccaggttt
    59761 cacccagtgg tctatgtacc cactactttg ggacaatatg gggatcagct acccagaact
    59821 aatcgagcgt ttggttgacc ttgccaagga aagttttgac aagcgcgaag cgcatttgat
    59881 ataaaatgaa agagagggta gaagccagaa ccatcactgc aaggtgacta gagttctcgg
    59941 acttcagccc tttttaaagg agtagaaatg aaattaacaa tccatgaagt tgcccaagtt
    60001 gttggagcca aaaatgatat cagtatcttt gaggacaccc agttagaaaa agctgagttt
    60061 gatagtcgtt tgattggaac tggagattta tttgtgcccc taaaaggtgt gcgtgacggt
    60121 catgacttta tcgaaagagc ttttgaaaat ggtgcggcag caaccctgtc tgagaaagag
    60181 gttgcaaatc atccctacat tctagtagat gatgttttga ctgcctttca acaactagct
    60241 gcctactatc ttgaaaaaac agctgttgat gtctttgcgg ttacgggttc aaatggcaag
    60301 acaacgacta aggatatgtt ggcgcattta ctgtcaacaa gatacaagac ctacaaaaca
    60361 caaggcaatt acaataatga gattggcctt ccttacacag ttctccacat gcctgaagga
    60421 acagaaaagt tggtcttgga gatggggcag gaccacttgg gagatattca tctcttgtct
    60481 gaattggctc gtccaaaaac agccatcgtg accttggttg gagaagctca tttggccttt
    60541 ttcaaagatc gttctgagat tgctaaagga aaaatgcaaa ttgcagacgg aatggcttca
    60601 ggttccttgc ttttagcgcc ggctgaccct atcgtagagg actatttgcc aactgataaa
    60661 aaggtggttc gttttggtca aggagcagag ctggaaatta ctgacttggt tgagcgcaaa
    60721 gatagtctga ccttcaaggc caatttctta gagcaagtcc ttgatttgcc agtaactggc
    60781 aagtacaatg cgacaaatgc tatgattgca tcctatgttg ccttgcaaga aggagtttca
    60841 gaggagcaaa ttcgtttggc cttccaacat cttgaattga cgcgtaaccg taccgagtgg
    60901 aagaaagcag ccaatggagc agacatcttg tcagatgttt acaatgccaa tccaactgct
    60961 atgaagctga ttttagagac cttctctgcc attccagcca atgaaggtgg caagaaaatt
    61021 gcagtgttgg cggatatgaa ggaacttggt gtccagtctg ttcaacttca taatcagatg
    61081 attttgagcc tttcgccaga tgtgcttgat actgttattt tctacggaga agatattgct
    61141 gaattagccc aacttgctag tcaaatgttc ccaatcggac acgtttatta cttcaagaaa
    61201 acagaagacc aagaccaatt tgaagaccta gttaagcagg tcaaagaaag ccttggggct
    61261 catgaccaaa tcctgctcaa aggctctaac tctatgaatc tagccaagtt ggtagaaagt
    61321 ttagaaaatg aagacaagtg attttgtcaa gtatttgcaa agaatgattg ccattacaga
    61381 tactggatta acctttacaa aagatccgtt tgaccgtgag cgctacgaag acttgcgaga
    61441 ccttctatct gaaatgttga atcaagcatc agaccttgat tccgaagaag tggcagaagt
    61501 cttgaagcca acttctgctt atgcgactcc cttaatggac gtccgtgctt ggattgttga
    61561 ggacgaaaag atttgtctgg ttaggggaca aggagaggat agttgggctt tgccaggtgg
    61621 ctttggtgaa gtcggctatt ctccaactga aaatattctc aaggaaattg aagaagaaac
    61681 cggttttaaa gccaaagttg aaagactgct agctgttttt gataccaatc gtttccaact
    61741 acagagcaaa caatatgcaa agtttgtttt tgaatgtaag cttctcgatg gacaattcca
    61801 agaaaatcaa gaaatcgctg accttcaatt ttttgcaatt gacccactgc cgaatttatc
    61861 tgaaaaacgc attaccaagg agcaaatcga gattctttgg caggtttatc aaggtcagag
    61921 ggagcaatat cttgactaag aagatgatta tcgtatttct aaattcattt ttcttaagta
    61981 gcatggtata ataaaatgca ggaaaatttt gaatcatgag gaagactaga tgaatttatg
    62041 ggatattttc tttacgactc aggcaaccga gccgcccaaa tttgaccttt tttggtatgt
    62101 tagcctattt acgctcttag ccttaacctt ttatacagcc catcgctatc gtgaaaagaa
    62161 ggtttaccaa cgatttttcc aaatcttgca gactgttcag ttaatccttc tttatggttg
    62221 gtactgggtc aatcatatgc cactgtcaga aagcctaccc ttttaccatt gccgtatggc
    62281 tatgtttgtg gtactcttgc ttcctggtca gtccaaatat aaacaatact ttgcattatt
    62341 gggaacattt gggacattag cagcctttgt ttatccagtg ccagatgctt acccttttcc
    62401 acatatcacc attctatcct ttatctttgg tcatttagca ctcttgggga actctctagt
    62461 ttatctattg agacagtata atgcgcgatt gctggatgtg aagggaattt ttctcatgac
    62521 ctttgcccta aatgccttga tttttgtggt caatttggtg acaggtggcg attacggatt
    62581 tttgacaaaa ccgccattgg ttggggatca cggtctagta gctaattatt tacttgtttc
    62641 aattgtgctg gtagctacta tcagtttgac taagaaaatc ttagaattct ttttagctca
    62701 agaagcagaa aaaatgattg caaaggaagc ttaacacaga gctttctttt ttgctcttag
    62761 agagttttta caagcagctt ataaaataag aatttctgaa tagacaaact caaaaaatgg
    62821 ctgggaaatt taggaaaaaa gcaagcacga ttaaattttt tgtgttataa tattttgtga
    62881 atagctatgc ctatgtttag ctatggaata atacgaagtg cgaaacttgg aagatagaga
    62941 ggaagcgatg taatggctag agaaggcttt tttacaggtc tagatattgg aacaagctct
    63001 gtcaaggtgc ttgtggccga gcagagaaat ggtgaattaa atgtaattgg cgtgagtaat
    63061 gccaaaagta aaggtgtaaa ggatggaatt attgttgata ttgatgcagc agcaactgct
    63121 atcaagtcag ccatttccca agcggaagaa aaggcaggca tttcgattaa atcagtaaat
    63181 gtcggcttgc ctggtaatct tttgcaggta gaaccaactc aggggatgat tccagtaaca
    63241 tctgatacta aggaaattac ggatcaagat gttgaaaatg ttgtcaaatc agctttgaca
    63301 aagagtatga cacctgaccg tgaagtcatt acctttattc ctgaagaatt tattgtggat
    63361 ggtttccaag ggattcgtga cccacgtggc atgatggggg ttcgccttga aatgcgtggt
    63421 ttgctttata caggacctcg tactatcttg cacaatttgc gtaagacggt tgagcgtgca
    63481 ggtgttcagg ttgaaaatat tatcatttca ccactagcaa tggttcagtc tgttttgaat
    63541 gaaggggaac gtgaatttgg tgctacagtg attgatatgg gggcaggtca aacgactgtc
    63601 gctacaatcc gtaatcaaga actccagttc acacatattc tccaagaagg tggagattat
    63661 gtaactaaag atatctccaa ggttttgaaa acctctcgca aattagcgga aggcttgaaa
    63721 ctgaattacg gggaagccta tccgcctctt gcaagcaaag aaaccttcca agtagaggtt
    63781 attggagaag tggaagcagt cgaagtgacg gaagcctact tgtcagaaat tatttctgca
    63841 cgaatcaagc acatccttga acaaatcaag caagaattag atagaaggcg tctattggac
    63901 ctccctggtg gtattgtctt aatcggtggg aatgccattt taccaggtat ggttgagctt
    63961 gctcaggaag tctttggcgt ccgtgtcaag ctttatgttc caaatcaagt tggtatccgt
    64021 aatccagcct ttgcgcatgt gattagttta tcagaatttg cgggtcaatt aacagaagtt
    64081 aatcttttgg ctcagggagc gataaaaggt gagaatgact taagtcatca gccaattagt
    64141 tttggtggga tgctgcaaaa aacagctcag tttgtacaat caacgcctgt tcaaccagct
    64201 cctgctccag aagtagagtc ggtggcgcct acagaaccaa tggcggattt ccaacaagct
    64261 tcacaaaata aaccgaaatt agcagatcgt ttccgtggct tgatcggaag catgtttgac
    64321 gaataaagag gaaaaataaa ttatgacatt ttcatttgat acagctgctg ctcaaggggc
    64381 agtgattaaa gtaattggtg tcggtggagg tggtggcaat gccatcaacc gtatggtcga
    64441 cgaaggtgtt acaggcgtag aatttatcgc agcaaacaca gatgtacaag cattgagtag
    64501 tacaaaagct gagactgtta ttcagttggg acctaaattg actcgtggtt tgggtgcagg
    64561 aggtcaacct gaggttggtc gtaaagccgc tgaagaaagc gaagaaacac tgacggaagc
    64621 tattagtggt gccgatatgg tcttcatcac tgctggtatg ggaggaggct ctggaactgg
    64681 agctgctcct gttattgctc gtatcgccaa agatttaggt gcgcttacag ttggtgttgt
    64741 aacacgtccc tttggttttg aaggaagtaa gcgtggacaa tttgctgtag aaggaatcaa
    64801 tcaacttcgt gagcatgtag acactctatt gattatctca aacaacaatt tgcttgaaat
    64861 tgttgataag aaaacaccgc ttttggaggc tcttagcgaa gcggataacg ttcttcgtca
    64921 aggtgttcaa gggattaccg atttgattac caatccagga ttgattaacc ttgactttgc
    64981 cgatgtgaaa acggtaatgg caaacaaagg gaatgctctt atgggtattg gtatcggtag
    65041 tggagaagaa cgtgtggtag aagcggcacg taaggcaatc tattcaccac ttcttgaaac
    65101 aactattgac ggtgctgagg atgttatcgt caacgttact ggtggtcttg acttaacctt
    65161 gattgaggca gaagaggctt cacaaattgt gaaccaggca gcaggtcaag gagtgaacat
    65221 ctggctcggt acttcaattg atgaaagtat gcgtgatgaa attcgtgtaa cagttgttgc
    65281 aacgggtgtt cgtcaagacc gcgtagaaaa ggttgtggct ccacaagcta gatctgctac
    65341 taactaccgt gagacagtga aaccagctca ttcacatggc tttgatcgtc attttgatat
    65401 ggcagaaaca gttgaattgc caaaacaaaa tccacgtcgt ttggaaccaa ctcaggcatc
    65461 tgcttttggt gattgggatc ttcgccgtga atcgattgtt cgtacaacag attcagtcgt
    65521 ttctccagtc gagcgctttg aagccccaat ttcacaagat gaagatgaat tggatacacc
    65581 tccatttttc aaaaatcgtt aagtaaatga atgtaaaaga aaatacagaa cttgtttttc
    65641 gagaagttgc agaggctagt ctgagtgctc atcgagagag tggttcggtc tctgtcattg
    65701 cagttaccaa gtatgtagat gtaccgacag cggaagcctt gcttccgcta ggtgttcatc
    65761 atatcggtga aaatcgtgta gataagtttc tggaaaaata tgaagcttta aaagatcgag
    65821 atgtgacttg gcatttgatt ggtaccttgc aaagacgtaa ggtgaaagat gtcattcaat
    65881 acgttgatta tttccatgca ttggactcag taaagctagc aggggaaatt caaaaaagaa
    65941 gtgaccgagt catcaagtgt ttccttcaag taaatatttc taaagaagaa agcaaacacg
    66001 gtttttcgag agaggaactg ctggaaatct tgccagagtt agccagacta gataagattg
    66061 aatatgttgg tttaatgacg atggcacctt ttgaggctag cagtgagcag ttgaaagaga
    66121 ttttcaaggc gacccaagat ttacaaagag aaattcaaga gaaacaaatt ccaaatatgc
    66181 ctatgaccga gttaagtatg ggaatgagtc gtgattataa agaagcgatt caattcggtt
    66241 ccacttttgt tcgtataggt acatcatttt ttaagtagga gagaaccatg tctttaaaag
    66301 atagattcga tagatttata gattatttta cggaggatga ggattcaagt ctcccttatg
    66361 aaaaaagaga tgagcctgtg tttactccag taaattcttc acaggaaccg gctctcccaa
    66421 tgaatcaacc ttcacagtcg gctggtacaa aagagaacaa tatcaccaga cttcatgcaa
    66481 gacaacagga attggcaaat cagagtcagc gtgcaacgga taaggtcatt atagatgttc
    66541 gttatcctag aaaatatgag gatgcaacag aaattgttga tttattggca ggaaacgaaa
    66601 gtatcttgat tgattttcag tatatgacag aggtgcaggc tcgtcgttgt ttggactatt
    66661 tggatggagc ttgtcatgtt ttagctggaa atttgaaaaa ggtagcttct accatgtatt
    66721 tgttgacacc agtgaatgtt attgtaaatg ttgaagatat ccgtttacca gatgaagatc
    66781 aacagggtga gttcggtttt gatatgaagc gaaatagagt acgataatga tttttttaat
    66841 tcgtatgatt tataatgcag tggatattta ctccctgatt ttggtagcct tcgctgtcat
    66901 gtcttggttt ccaggtgcct acgaatccag tttaggtcgt tggattgtag cgttggtgaa
    66961 accagtgctt gctcccttgc aacgcctgcc tttacagata gcgggtcttg atttatctgt
    67021 ttgggtcgcg attgttttgg ttcgattttt aggagaaaac ctagtgcgtt ttctggcgat
    67081 gataggatga ataaagggat ttatcagcat ttctccatag aagatcgtcc atttcttgac
    67141 aagggaatgg aatggataaa gaaggtagaa gatagctatg ctcctttttt aactcctttt
    67201 atcaatcctc atcaggagaa gctattaaag attttggcca aaacctatgg tcttgcttgt
    67261 agcagtagtg gggaattcgt ctcgagtgag tatgttcgag ttttattata cccagattat
    67321 ttccaaccag agttttcaga ttttgaaata tctctccagg aaattgtgta ttccaataaa
    67381 tttgaacatt taacgcatgc taagatttta gggacagtca tcaatcaatt agggattgaa
    67441 cggaaacttt ttggagatat cctagtagat gaagaacggg cgcagattat gattaatcag
    67501 cagtttcttc ttctctttca agatggacta aagaaaattg gtcgtatacc tgtttcgctg
    67561 gaggaacgtc ctttcaccga gaaaatagat aagctagaac agtatcgaga actggattta
    67621 tctgtgtcta gttttcgatt agatgttctt tgttcaagtt ggagacttga ttagtgtgag
    67681 aaaatttggt cgcttgagat tacttcaaga taagggacaa acgaaaaaag agaagaaaaa
    67741 aataaccgtc cagttattat taagtaagtg aggaatagaa tgccaattac atcattagaa
    67801 ataaaggaca agacttttgg aactcgattc agaggttttg atccagaaga agtcgatgaa
    67861 tttttagata ttgtggttcg tgattacgaa gatcttgtgc gtgcgaatca tgataaaaat
    67921 ttgcgtatta agagtttaga agagcgtttg tcttactttg atgaaataaa agattcattg
    67981 agccagtctg tattgattgc tcaggataca gctgagagag tgaaacaggc ggcgcatgaa
    68041 cgttcaaaca atatcattca tcaagcagag caagatgcgc aacgcttgtt ggaagaagct
    68101 aaatataagg caaacgagat tcttcgtcaa gcaactgata atgctaagaa agtcgctgtt
    68161 gaaacagaag aattgaagaa caagagccgt gtcttccacc aacgtctcaa atctacaatt
    68221 gagagtcagt tggctattgt tgaatcttca gattgggaag atattctccg tccaacagct
    68281 acttatcttc aaaccagtga tgaagccttt aaagaagtgg ttagcgaagt acttggagaa
    68341 ccgattccag ctccaattga agaagaacca attgatatga cacgtcagtt ctctcaagca
    68401 gaaatggaag aattacaagc tcgtattgag gtagccgata aagaattgtc tgaatttgaa
    68461 gctcagatta aacaggaagt ggaaactcca actcctgtag tgagtcctca agttgaagaa
    68521 gagcctctgc tcatccagtt ggcccaatgt atgaagaacc agaagtagct ccagtgcatc
    68581 cgacaggtcc aacaccagct acagaaactg ttgattcagc accgggattt gaagcaccgc
    68641 aagaatctgt tacaatttta taagaaatat tctgagaaca atatcttatc cttatattcc
    68701 cagcgagcag gagatggtgt gagtcctgca ttccctatcg ataagattat cctctcaaac
    68761 tatcaagtct gaatctagta agatttgacg ttccccacgt tacgggataa gagggagaaa
    68821 gactaaaact ttttccgaat aaaggtggta ccacgatttt cgtccttttt ggaagtcgtg
    68881 gtttttaatt tgttattatt tataaaggag ataccatgaa actcaaagac acccttaatc
    68941 ttgggaaaac tgaattccca atgcgtgcag gccttcctac caaagagcca gtttggcaaa
    69001 aggaatggga agatgcaaaa ctttatcaac gtcgtcaaga attgaaccaa ggaaaacctc
    69061 atttcacctt gcatgatggc cctccatacg ctaacggaaa tatccacgtt ggacatgcta
    69121 tgaacaagat ttcaaaagat atcattgttc gttctaagtc tatgtcagga ttttacgcac
    69181 catttattcc tggttgggat actcatggtc tgccaatcga gcaagtcttg tcaaaacaag
    69241 gtgtcaaacg taaagaaatg gacttggttg agtacttgaa actttgccgt gagtacgctc
    69301 tttctcaagt agataaacaa cgtgaagatt ttaaacgttt gggtgtttct ggtgactggg
    69361 aaaatccata tgtgaccttg actcctgact atgaagcagc tcaaattcgt gtatttggtg
    69421 agatggctaa taagggttat atctaccgtg gtgctaagcc agtttactgg tcatggtcat
    69481 ctgagtcagc ccttgctgaa gcagagattg aataccatga cttggtttca acttcccttt
    69541 actatgccaa caaggtaaaa gatggcaaag gagttctaga tacagatact tatatcgttg
    69601 tctggacaac gactccattt actatcacag cctctcgtgg tttgacggtt ggtgcagata
    69661 ttgattacgt tttggttcaa cctgctggtg aagctcgtaa gtttgtcgtt gctgctgaat
    69721 tattgactag cttgtctgag aaatttggct gggctgatgt tcaagttttg gaaacttacc
    69781 gtggccaaga actcaaccac atcgtaacag aacacccatg ggatacagct gtagaagagt
    69841 tggtaattct tggtgaccac gttacgactg actctggtac aggtattgtc catacagccc
    69901 ctggttttgg tgaggacgat tacaatgttg gtattgctaa taatcttgaa gtcgcagtga
    69961 ctgttgatga acgtggtatc atgatgaaga atgctggtcc tgaatttgaa ggtcaattct
    70021 atgaaaaggt agttccaact gttattgaaa aacttggtaa cctccttctt gcccaagaag
    70081 aaatctctca ctcatatcca tttgactggc gtactaagaa accaatcatc tggcgtgcag
    70141 ttccacaatg gtttgcctca gtttctaaat tccgtcaaga aatcttggac gaaattgaaa
    70201 aagtgaaatt ccactcagaa tggggtaaag tccgtcttta caatatgatc cgtgaccgtg
    70261 gtgactgggt tatctctcgt caacgtgctt ggggtgttcc acttcctatc ttctacgctg
    70321 aagatggtac agctatcatg gtagctgaaa ctattgaaca cgtagctcaa ctttttgaag
    70381 aacatggttc aagcatttgg tgggaacgtg atgccaaaga cctcttgcca gaaggattta
    70441 ctcatccagg ttcaccaaac ggcgagttca aaaaagaaac tgatatcatg gacgtttggt
    70501 ttgactcagg ttcatcatgg aatggagtgg tggtaaaccg tcctgaattg acttacccag
    70561 ccgaccttta cctagaaggt tctgaccaat accgtggttg gtttaactca tcacttatca
    70621 catctgttgc caaccatggc gtagcacctt acaaacaaat cttgtcacaa ggttttgccc
    70681 ttgatggtaa aggtgagaag atgtctaaat ctcttggaaa taccattgct ccaagcgatg
    70741 ttgaaaaaca attcggtgct gaaatcttgc gtctctgggt aacaagtgtt gactcaagca
    70801 atgacgtgcg tatctctatg gatatcttga gccaagtttc tgaaacttac cgtaagattc
    70861 gtaacactct tcgtttcttg attgccaata catctgactt taacccagct caagatacag
    70921 tcgcttacga tgagcttcgt tcagttgata agtacatgac gattcgcttt aaccagcttg
    70981 tcaagaccat tcgtgatgct tacgcaaact ttgaattctt gacaatctac aaggccttgg
    71041 tgaactttat caacgttgac ttgtcagcct tctaccttga ttttgccaaa gatgttgttt
    71101 acattgaagg tgccaaatca ctggaacgcc gtcaaatgca gactgtcttc tatgacattc
    71161 ttgtcaaaat caccaaactc ttgactccaa tccttcctca cactgcggaa gaaatctggt
    71221 catatcttga gtttgaagcc gaagacttcg tccaattgtc agaattacca gaagttcaaa
    71281 cttttgctaa ccaagaagaa atcttggata catgggcagc cttcatggac ttccgtggac
    71341 aagcacaaaa agccttggaa gaagctcgta atgcaaaagt tatcggtaaa tcacttgaag
    71401 cacacttgac agtttatcca aatgaagttg tgaaaactct actcgaagca gtaaacagca
    71461 atgtagctca acttttgatc gtgtctgagt tgaccatcgc agaagaacca gctccggaag
    71521 ctgcccttag cttcgaagat gtagtcttca cagttgaacg cgctgcaggt gaagtatgtg
    71581 accgttgccg tcgtattgac ccaacaacag cagaacgtag ctaccacgca gtcatctgtg
    71641 accactgtgc aagtatcgta gaagaaaact ttgcagatgc agtcgcagaa ggatttgaag
    71701 agaaataaga ttgaaaagtc taggtaaaac tcaatttgag aagaaaagac aactaatttt
    71761 atagtctatt aaacgcattg tatcacgttt ttgaacacct gatatgatgc gttttttatt
    71821 tattttaaaa atttgcgagg tatgactttt tatactcaac aagaatcaaa gagaaactta
    71881 gcaagctaac agtagtaata taaaatagga atttgatatt agggataaga ttggtaaata
    71941 gtgtaatatt tttacaacaa taaatttata tagttatttc tggtttctga aaagtattat
    72001 attatatttt atttcatatt atacaaattt ttattttata atatcagaaa atactttttt
    72061 taaaaagcaa atatgataca attttatttg aaaaaaaata aaaaaggaga ttttattatg
    72121 aaatcaagtg gtatcgtcgg tcttgtggga ggaattttac ttcttatttg tccttttgtc
    72181 ttgttgggaa cagcggtaaa tacagctgct acaactctta atggaggagc tactgcaggg
    72241 gctttttcag gtgttgcctt actcttgaat gccttgaaga ttgcaaatct tgttcttggt
    72301 atcattgcta ttgtttacta taaaggagat aagcatgtag gtgcagctcc gtctgtacta
    72361 atgattgttt ctggtgaagt tagtctcatt ccattcttag gatgggttgg ggggattctt
    72421 gctattatcg gaggatctct attccttgca acattgaaga aattcaaatc agaagaataa
    72481 aaggtatttt agcatgaaaa gaacaaaaaa gtttatcggt ataggagtag ctctattatc
    72541 tctttctctt ctagttgcat gtggaacata aagttcaaag aatacttcaa caagtaatga
    72601 tgagaagaca gtagcaacat ccaatagttc aaaagaaaca atcactttcg atacaccggt
    72661 tgtaacagac gatgcgattg aatcaatacg cacttatgca gattatatag atctttataa
    72721 aaatattttt gatgattatt ttactaaagc tgaggaaggt ttcaaaggca caactatgga
    72781 aaataatgac tcgtttacta aactaaaaga gtcaactcaa aaattattcg atgcgcagaa
    72841 aaaaaggtta aataatgaag atagaataga aacaaccaaa aacaatgtga ttgccaaaca
    72901 ttgtcaaaca gtcctttcct ttttggtttt gactagcttt tttgtgaaaa attgtgtaaa
    72961 atagaataga taaacgaggg gaaacctcgg aaaatttaaa ggagaatcca tctaatggta
    73021 aaattggttt ttgctcgcca cggtgagtct gaatggaaca aagctaacct tttcactggt
    73081 tgggctgatg ttgatttgtc tgaaaaaggt acacaacaag cgattgacgc tggtaaattg
    73141 atcaaagaag ctggtatcga atttgaccaa gcttacactt cagtattgaa acgtgctatc
    73201 aaaacaacta acttggctct tgaagcttct gaccaattgt gggttccagt tgaaaaatca
    73261 tggcgcttga acgaacgtca ctacggtggt ttgactggta aaaacaaagc tgaagctgct
    73321 gaacaatttg gtgatgagca agttcacatc tggcgtcgtt catacgatgt attgcctcca
    73381 aatatggacc gtgatgatga gcactcagct cacacagacc gtcgttatgc ttcacttgac
    73441 gactcagtca ttccagatgc tgaaaacttg aaagtgactt tggaacgtgc tcttccattc
    73501 tgggaagata aaatcgctcc agctcttaaa gatggtaaaa acgtattcgt aggagctcac
    73561 ggtaactcaa tccgtgccct tgtaaaacac atcaaaggtt tgtcagatga tgagatcatg
    73621 gacgtggaaa tccctaactt cccaccattg gtattcgaat tcgacgaaaa attgaacgtt
    73681 gtttctgaat actaccttgg aaaataaaaa attgtaagcc taggattgat ttctaggctt
    73741 tttatgttag tatggaagta tgataaggaa taaaaaacaa gattatgtac tggcctacaa
    73801 gcaaccagct tcaaccactt acatgggttg ggaagaagaa gctttaccga taggcaatgg
    73861 ttctttagga gcaaaagtat ttggccttat aggggctgaa cggattcaat ttaatgaaaa
    73921 aagtctctgg tctggaggtc cacttcctga tagttcagat tatcagggtg gaaatcttca
    73981 ggatcagtat gtttttttag ctgagattcg gcaggctttg gagaagagag attacaatct
    74041 ggctaaggaa ctggctgagc agcacctaat tgggccaaaa acgagtcaat atgggaccta
    74101 tctgtctttt ggggatattc acattgagtt cagccagcaa ggtacgactt tgtctcaggt
    74161 gacggactat cagagacagc tgaatattag taaggcactt gcgacgactt cttatgtcta
    74221 taagggaacg cgatttgaac gtaaagcttt tgcgagtttt ccagatgatc tcttgattca
    74281 atgttttact aaggaagggt tggaaactct agattttact atagaactat ccttgacctg
    74341 tgatttggct tctgatggaa agtatgagca ggaaaaatct gattacaagg agtgtaagtt
    74401 ggatattact gattctcata tcttgatgaa gggaagagtt aaggataatg atctgcggtt
    74461 tgctagttat ctagcttggg aaacggatgg agatattaga gtttggtcag atagggttca
    74521 gatatcagga gccagttatg ccaatctctt cttggccgct aagacggatt ttgcccaaaa
    74581 tcctgctagc aattatcgca agaaactaga tttagagcaa caggtgatag acttggtgga
    74641 cacagctaaa gaaaagggct atacccaatt gaaatcaagg catatcgagg actaccaagc
    74701 cttattccag cgtgttcaat tggatttgga agctgatgtt gacgcatcca ctacagatga
    74761 tttgttaaaa aattataagc cacaagaagg gcaggctttg gaggagctgt tcttccagta
    74821 tggacggtat ttattgatta gttcgtccag agactgccca gatgctctac cagctaacct
    74881 acagggagtc tggaatgcgg tcgacaatcc tccttggaat tcggactatc acttaaatgt
    74941 caatctgcag atgaattatt ggccagccta tgttaccaat ctcctagaga cggtctttcc
    75001 agtcatcaac tatgtagatg atttgcgtgt ctatggtcgt ctagcggctg taaagtatgc
    75061 aggaatcgtc tctcaaaaag gtgaggaaaa tggttggttg gttcatactc aagcgactcc
    75121 ctttggttgg acggcacctg gttgggatta ctattggggt tggtcaccag ctgccaatgc
    75181 gtggatgatg caaaccgttt atgaagccta ttcattttat agggaccaag actatctcag
    75241 ggagaaaatt tatcccatgt tgagggaaac ggttcgtttt tggaatgcct ttttacataa
    75301 ggatcagcag gcgcagcgtt gggtctcttc tccgtcttat tccccagaac atgggccgat
    75361 ttcgattggc aatacctatg accaatctct gatttggcag ttatttcatg attttattca
    75421 ggctgctcag gaattgggac tggatgagga cttgttgact gaggttaagg agaagtctga
    75481 tttactaaat cctttgcaaa tcactcaatc tggtcgaatc agggagtggt atgaggagga
    75541 agagcagtat tttcaaaatg agaaagtgga ggcccagcat cggcacgctt cccatctagt
    75601 gggactctat tctggcaatc tctttagcta caagggacaa gagtatattg aagcggcgcg
    75661 tgctatcctc aatgatcgtg gagatggcgg cacaggctgg tccaaggcta ataagatcaa
    75721 tctctgggcg cgtttgggag atggcaatcg agcccataaa ttattggcag agcagttaaa
    75781 gacatccacc ttgccaaatc tttggtgtag ccatcctcct tttcagatag atggtaattt
    75841 tggtgctact agtggcatgg cagaaatgtt actccagtct catgcagctt atctggtacc
    75901 tctagctgcc ctacctgatg cttggtcaac aggttctgtt tcaggcttaa tggcacgtgg
    75961 acattttgaa gtgagcatga gctgggaaga taaaaaactc ttacagttga ccattttatc
    76021 aaggagtgga ggagatttgc gagtttctta tccagatatt gagaagagtg tgattaaaat
    76081 gaatcaagaa aaaataaaag cgaaatgcat ggggaaagat tgtatttcgg tggcaacagc
    76141 agaaggtgat cttgttcaat tttattttta agaagatgtt ataaggcagt aatttgaaac
    76201 ttccttttaa taaggatttg agaatatagg cagtttccaa ctagttgaaa aagcgttata
    76261 atgataatag gaagtaatac tcaatgaaaa tcaaagagca caaactagga agctagccgc
    76321 aggttgctca aaacagtgtt ttgaggttgt agatggaagc tgacgtggtt tgaagagaga
    76381 ttttcgagga gtataatttg tttgatagag ggtgggtctg atggcttata ttgagatgaa
    76441 acactgttac aagcgttatc aggttgggga cacggagatt gtggccaatc gtgatgtgaa
    76501 ttttgagatt gaaaaggggg agctggttat tatccttggt gcttcaggtg caggcaagtc
    76561 aacagttctt aaccttcttg ggggaatgga taccaatgat gaaggggaaa tctggattga
    76621 tggtgttaat attgcggatt atagttccca ccagcgtacc aattaccgta gaaatgatgt
    76681 ggggtttgtt tttcagtttt ataatctagt ttctaatctg acagctaagg aaaatgtgga
    76741 actggcttct gaaattgtga cagatgcctt gaatcctgat caggtcttga cagatgtagg
    76801 tctggctcat cgtctcaata actttccagc ccagctttct ggaggggagc aacagcgagt
    76861 ctccattgca cgcgcggtag ccaaaaatcc taaaattctc ctttgtgatg aaccgactgg
    76921 agccttggat tatcagacgg gcaagcaggt tttgaaaatt ctccaagaca tgtctcgtca
    76981 aaagggagcg acggtgatca tcgtgactca taatggagct ttggcgccca ttgctgatcg
    77041 cgtgattcaa atgcacgatg ccagtgtcaa ggatgtggtg ctcaaccagc atcctcagga
    77101 tattgacagt ttggagtact agcatgatca agcgaaaaac ttattggaag gacttaattc
    77161 agtccttcac aggctccaag gggcgttttt tatccatctt gatcctgatg atgttgggat
    77221 ctctagcctt agtaggcctc aaagtaacca gtcccaacat ggaggcgaca gctaatgctt
    77281 atttaacaac tgctcaaacc ttggatttgg cagtcatgtc taactatggc ttggatcaag
    77341 cagaccaaga agaactaaaa cagacggagg gcgcagaggt cgagtttggc tatttgacag
    77401 atgtgactat ggataatggg caggatgcca ttcggctgta ctccaaacca gagcgaattt
    77461 caacctttca gctaagaaag ggacgacttc ctcagtcaga caaggaaatc gctttggcca
    77521 ctcatttgca aggccaatac agcgtgggac aggagattag ttttaaagaa aaagaagagg
    77581 gtcattcctc tttaaaagac catacttata ccattactgg ttttgtggat tcggctgaaa
    77641 tcctctccca gcgagatatg ggctacgcag gaagtggaag tgggactctg acagcctatg
    77701 gggtgatttt acctagtcag tttgatcaga aagtctacaa tatagctcgt ttgaaatatc
    77761 aagatttagc aggtttaaat gccttttcat cagcttatga agaaaaatcc aagcaacatc
    77821 aggaagacct tgaacaaact ttatcagata atggcaaggt acgtctgcaa cttttgaaaa
    77881 aagaaggaca agagtctcta gacaaggggc aagagaccct tgacaaggct cagactaatt
    77941 tgcaggaagg caagcgtcgt ttagcagctg ctcaagctcg tatacaggct caagaaagtc
    78001 aactagcctt gtttcctcaa gttcagagag agcaggctag tgctcaactt acccaagcca
    78061 agcaggaatt gggcaaggaa gaggataaac taaagcaagc tgaacaaaat ctagcccaag
    78121 aaaaggaaaa attagaaaaa catcagcaag tcttggacga tttggcggag ccaaggtatc
    78181 aggtctataa tcgtcagacc atgccaggtg gtcagggcta tcttatgtat agcaatgctt
    78241 catccagtat tcgagcagtg ggcaatatct ttcctgtggt actttatgcc gtagcatcca
    78301 tggtgacctt tacgaccatg actcgctttg tagacgaaga gcgaactcat gcagggattt
    78361 ttaaggcctt gggttaccgt agtaaggata ttatcaccaa gtttctcctt tatggactag
    78421 tagctgggac tgtcggaacg gctctaggta gtatacttgg tcattatttg ctagccagtg
    78481 taatttcaag tgtcattaca aaaggcatgg tggtgggaga aacccagatt cagttctatt
    78541 ggacctatag cttactagct cttgtcttga gctggttggc gagtgtgtta ccagcctatc
    78601 tggtggcttg gagggaactt catgccgaag cagcccagct tctacttcct aaacctcctg
    78661 tcaaaggagc taaaatctta ttggagcgta tcggttttat ctggcgtcgt ctcagtttta
    78721 ctcataaggt aacagcccgc aacatctttc gttataagca gagaatgttg atgacaatct
    78781 ttggtgtggc aggttctgta gctctgctct ttgcaggttt gggaatccaa tcttctgtag
    78841 caggagttcc gtctaaacag tttcaacaaa tccaacagta tcagatgctt gtctctgaaa
    78901 atcctagtgc gaccaatcag gacaaggtag agctagcaga agtgttgaaa gggcaggaga
    78961 tactagccta ccagaaaatc tattctaaaa cgctagacaa ggatttcaaa ggcaaggctg
    79021 gtcttcaaaa cattactctt atgatgatag agaaggaaga tttgactccc tttatccatc
    79081 ttcaacatca tcagcaggag ctgacattaa aagatggcat cgttattaca gctaaactcg
    79141 cccagctggc aggtgtcaag gttgggcaga ctttagaaat tgaaggtaag gaactaaagg
    79201 tcgctgctat tactgagaac tacgttggtc actttattta tatgagtcag gctagctatg
    79261 agcaacttta cggacagcta ccccaagcca acacttatct ggtctcatta agggatacca
    79321 gtgcaactag tatcgaaagt caggcgggct tgcttatgaa tcaatctgcg gtgtccagcg
    79381 ttgtccaaaa tgcttcagcc attcgactct atcgctagct cactcaatca gaccatgacc
    79441 atcttggtca tcgtatcagt tctattagct attgtcatcc tttacaatct gaccaatatc
    79501 aacgtagctg agagaatccg tgaactctcc actatcaagg ttctcggttt tcataataat
    79561 gaagtcaccc tctacattta ccgtgagacg attgtgctgt cccttgtggg aatcgtactt
    79621 ggtctggtag ctggtttcta tttacaccaa tttttgattc aaatgatttc gcctgcgact
    79681 attctctttt atccgcaggt aggctgggaa gtctatgtaa tcccagtggc aacagtaagc
    79741 atcattttga ccttgcttgg tttcttcgtc aattattatc tgagaaaggt tgatatgtta
    79801 gaagccctga aatctgtaga gtaaggtagt tatttttagc tgattgaact tctatttact
    79861 aatattcaaa aatcctctgt cacaaagagc agggagctct ttgtgacaga ggattttttc
    79921 tatagggctt tagcagctgc aattgcggct tcgaagtttg gctcagaatt gatattatcc
    79981 acgtattcaa cgtagcgaat cgtattgtca gtatcgagga caaagactgc gcgtgctaat
    80041 aggtgccatt cgttgatcaa gagggcataa tcgcgcccga aagaatggtc aaagtagtct
    80101 gaaagcataa tggcattgtc aaggccttca gcaccgcacc aacgtttttg agcaaaaggt
    80161 aggtccattg aaacagtcaa tacgaccgtg ttgtccagtc cagccaattc ttcattaaaa
    80221 cgacgtgttt gagttgagca gatgcctgta tcgatagaag gaacgacact caagactttt
    80281 ttcttgccat caaaatcagc cagagatttt ttagaaagat ctgttgtagt aagagaaaaa
    80341 tcaagcgcct tgtcgccgac ttgtagttgt ttacctgtaa agctcacagg atttccgaga
    80401 aaagttacca taggatactc caatcttttt tcttccattg tatctgaaac agtcagaatt
    80461 ttccaatgat ttgaccggaa atgtgggcat agaaaaaacg ccagctcaca tgagaatgac
    80521 gtttttcaga ggcttatttt gccaatcctt cagcaatctt gtcaaggttg tatttcatca
    80581 tgctgtagta gctgtcgcct tctttacctt gttctgcgat agagtcagta aagatttgtg
    80641 cgtagattgg gatgtttgtg tcttgagaaa cagttttcat tggacggtca tccacacttg
    80701 attctacaaa gagtgatgga acttttgttt ggcgaagttt ttcaaccaag gtcttgattt
    80761 gttcaggagt tccttcttct tcagtattga tttcccagat gtaagcactt gggacaccat
    80821 aggctttaga gaagtatttg aatgctcctt cgctggttac aatgagtttc ttttcagcag
    80881 ggatcttatt aaatttatcc ttactttctt tatcaagttt gtctaactta tcagtatatt
    80941 ctttgagatt tttttcatag aattctttat tgttagggtc tttggcgctc aattgtttgg
    81001 cgatattttt agcaaaaata ataccgtttt caaggttaag ccaagcgtgt gggtcttctt
    81061 ttcctttttc attttgacct tcaaggtaga taacatcaac gccgtcgctg actgcgaagt
    81121 agtctttgtt ttcagttttc ttggcatttt ctaccaattt tgtaaaccaa gcattgccac
    81181 ctgtttcaag gttgataccg ttatagaaaa tcaaatcagc ctcagaagtt ttcttaacgt
    81241 cttcaggaag tggttcgtat tcgtgtgggt cttgcccaat cggaacgata ctatgaaggt
    81301 caattttgtc accagcaata tttttagtaa tatcagcgat gattgagttt gtagcaacaa
    81361 cttttagttt ttgaccagaa gttgtatctt tttttccgct agcacatgct acaagaatga
    81421 ttgcagaaag aaagagaacg agtaatgtac ctaatttttt cattagatcc tccaaattat
    81481 tagggctttg ccccttattt taacaaatgt ttatttttca gtttcaaata tcgttgtttg
    81541 ggagcgataa agaagctaat gagaaagaaa ctagcagctg taagcacgat actagaacct
    81601 gccgcaacat taaaactata gccaataaag agtcccaaaa ctgaagcagt agctccgaag
    81661 gttgaggaaa ggaaaatcat gcttttcaga ctattagcat acagataagc agttgcagct
    81721 ggggtaatca gcatggctac aatcaggata gttccgacac tttgcatggc tgtcacagac
    81781 acgagagtca ggagtaccat gagaaggtag tgatagaaat tgacaggcat tcccatggct
    81841 ttagccaaga gttcatcaaa ggaagttatc aagagttgct tgaagaaaat ccagattaac
    81901 aagaggatgg ctgcccccac acccatagta ataaacatat ccgtatcttg gacggccagg
    81961 atattaccaa aaaggatatg gaaaaggtca gttgaacttt tagcgacacc aatcaagatg
    82021 ataccgaggg ctaagaaaga agaaaaggta atgccgatgg cggtatcgct tttgataatc
    82081 gagtttcctt tgatgtaggt aatgatgatg gcagctagca atccaaagac aatggctccg
    82141 ataaagaagt caaggcccaa gatgaaggag agggctacac ctggtaagac agcatgtgaa
    82201 atggcatctc ccatgagtga catcccgcgt agaataatga aacatcccac agctccagct
    82261 acaatcccga cgacaatagc tgttatcaag gcattttgta ggaaatggaa tttttgcaat
    82321 ccatcgataa attctgcaat cataggtcac ctccattgaa aaagagttga ttaccgtaag
    82381 cttcttttag attggtttcg gtaaaagttt cttttgttgg accaaaggca atcacttctc
    82441 gattgacaag taagacttga tcgaagtagt ggggaatctt gctgaggtcg tggtgaacga
    82501 tgagaaccgt cttcccagct tttttcaaat ctctcagcgt attcatgatg atttcctcac
    82561 tgacagagtc aatcccagca aagggttcat ccaagaggat atagtcggct tcctgcacca
    82621 aacatctggc aatcaaaacc cgctggaatt gacctccaga cagttgacta atttgacgtt
    82681 cagcgtagtc agctaggccg acgatttcaa gggcctcttg cactttcttc caatgtttag
    82741 cctttaaact tcgaaagaga ggaatagagg gaaatagtcc taacgagacg cattccttga
    82801 ccttgatggg aaagttgtag tcgatattga ttttttgttc gacataggca attcggtgta
    82861 aggatttttt aacttccttg tcatcgagaa atgcctgacc ttgatgtggg ataattccca
    82921 gcataccttt taatagtgtt gatttcccag cgccgtttgg accaatgatg ccggtaattg
    82981 ttggtccatg gagcactagt gaaatatcct taagtgccaa cgtttctttg taggagacac
    83041 tgaggttttc gatacgtatc ataaacttgt attcctcctg tctcttaata tacattaaaa
    83101 aaaaaattaa gtcaagttaa tttttgaaaa aattaaaata ataactgaaa aataga
//
LOCUS       DAVBEO010000004        68866 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 009
            SAMEA1678075-rid20185393.denovo.004, whole genome shotgun sequence.
ACCESSION   DAVBEO010000004 DAVBEO010000000
VERSION     DAVBEO010000004.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678075
            Sequence Read Archive: ERR226392
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 68866)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 68866)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980207.1
            Genome Coverage       :: 150x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:50:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 72 of 147
            Pseudo Genes (incomplete)         :: 72 of 147
            Pseudo Genes (internal stop)      :: 42 of 147
            Pseudo Genes (multiple problems)  :: 32 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..68866
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678075-rid20185393.denovo.004"
                     /strain="KS 009"
                     /db_xref="taxon:1313"
     gene            1..262
                     /locus_tag="VQ543_000275"
                     /pseudo
     CDS             1..262
                     /locus_tag="VQ543_000275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; internal stop; incomplete; missing
                     N-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
     gene            259..477
                     /locus_tag="VQ543_000276"
     CDS             259..477
                     /locus_tag="VQ543_000276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000028153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2611072.1"
                     /translation="MSISPRFEALEQAIASKDLEKVREAFKKMNSTWTINESVVRDNS
                     TAHYGRVETAISFLPSSMETEPTDESGT"
     gene            complement(534..818)
                     /locus_tag="VQ543_000277"
     CDS             complement(534..818)
                     /locus_tag="VQ543_000277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type B 50S ribosomal protein L31"
                     /protein_id="HET2611073.1"
                     /translation="MARKETMAERKYCKMKKDIHPEYRPVVFMDTTTGYQFLSGSTKR
                     SNETVEFEGETYPLIRVEISSDSHPFYTGRQKFTQADGRVDRFNKKYGLK"
     gene            complement(872..1807)
                     /locus_tag="VQ543_000278"
     CDS             complement(872..1807)
                     /locus_tag="VQ543_000278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional oligoribonuclease/PAP phosphatase
                     NrnA"
                     /protein_id="HET2611074.1"
                     /translation="MEICQQILEKIKEYNTIIIHRHMKPDPDALGSQVGLKALLEHHF
                     PEKTIKAVGFDEPTLTWMAEMDLVEDRAYQGALVIVCDTANTARIDDKRYSQGDFLIK
                     IDHHPNDDVYGDLSWVDTSSSSASEMITLFAQTTQLALADRDAELLFAGIVGDTGRFL
                     YPSTTARTLRLAAYLREHNFDFAALTRKMDTMSYKIAKLQGYIYDHLEVDENGAARVI
                     LSQKILKQYNVTDAETAAIVGAPGRIDSVSLWGIFVEQADGHYRVRLRSKIHPINEIA
                     KEHDGGGHPLASGANSYSLEENEIIYQKLKNLLKN"
     gene            1911..2354
                     /locus_tag="VQ543_000279"
     CDS             1911..2354
                     /locus_tag="VQ543_000279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HET2611075.1"
                     /translation="MALAKIVFASMTGNTEEIADIVADKLRDLGLDVDVDECTTVDAS
                     DFLEADIAIVATYTYGDGELPDEMMDFYEDLADLNLNGKIYGVVGSGDTFYDEFCKAV
                     DDFDRVFVSTGAEKGSECVKVDLSAEEEDIERLEQFAEELAAKVG"
     gene            2470..2736
                     /locus_tag="VQ543_000280"
     CDS             2470..2736
                     /locus_tag="VQ543_000280"
                     /EC_number="5.4.99.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate mutase"
                     /protein_id="HET2611076.1"
                     /translation="MDLDIIRQEIDQIDDQIVKLLEERMHLVEGVVAYKKASGKPILD
                     TKREEVIFEKVRSRVEDKRYQETIVATFSYILKRSRDYQDQNIK"
     gene            2733..3107
                     /gene="crcB"
                     /locus_tag="VQ543_000281"
     CDS             2733..3107
                     /gene="crcB"
                     /locus_tag="VQ543_000281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000712114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fluoride efflux transporter CrcB"
                     /protein_id="HET2611077.1"
                     /translation="MKKEQFYPLGIFLAAMLGGLVRYLVSTWLPASPDFPWGTLFVNY
                     LGIFCLIFLVKGYLVYKGTSKGLILALGTGFCGGLTTFSSLMLDTVKLLDTGRYFSLV
                     LYLLLSIGGGLLLAYYLGRKKW"
     gene            3101..3430
                     /gene="crcB"
                     /locus_tag="VQ543_000282"
     CDS             3101..3430
                     /gene="crcB"
                     /locus_tag="VQ543_000282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000237393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fluoride efflux transporter CrcB"
                     /protein_id="HET2611078.1"
                     /translation="MVIVYLAIACGLGALVRYFFSRYNQASKLPLGTLIANLLGCFLI
                     GVFYNHVESKEVYAILATGFCGGLTTFSTLNDELQRLLSDKKVFYSYLTLTYIGGLVA
                     IFLGILL"
     gene            3549..3896
                     /gene="rplS"
                     /locus_tag="VQ543_000283"
     CDS             3549..3896
                     /gene="rplS"
                     /locus_tag="VQ543_000283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L19"
                     /protein_id="HET2611079.1"
                     /translation="MNPLIQSLTEGQLRTDIPSFRPGDTVRVHAKVVEGNRERIQIFE
                     GVVIARKGAGISENYTVRKISNGVGVERIFPIHTPRVEKIEVVRYGKVRRAKLYYLRA
                     LQGKAARIKEIRR"
     gene            3939..4010
                     /locus_tag="VQ543_000284"
     tRNA            3939..4010
                     /locus_tag="VQ543_000284"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:3972..3974,aa:Arg,seq:cct)
     gene            complement(4177..5175)
                     /locus_tag="VQ543_000285"
     CDS             complement(4177..5175)
                     /locus_tag="VQ543_000285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001008999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAP domain-containing protein"
                     /protein_id="HET2611080.1"
                     /translation="MNFFSKLFNLKQNNHNRDTNSDCNNFYLNELECGLTPGQLILID
                     WTQKTGRNYNFPRYFKYSLQIDPESTHNQLYKLGYFTKNKTLSYLTVVELKTILSKHN
                     LATSGKKAELITRIINNVNIDNLDIPFEFKLTKEAQNLIIEHSDYIKAYYDKDISMED
                     YCKEKNNISFKATFGDIKWSLLNKQAHRNTVSGDFGCLSNTRKAQGRHLEQEGNIKHA
                     LIYYIESLIITISGLENNFSATDYPVYYPDSIPDYSLKHIQTLMESLSDDDYDFAFDE
                     ALFRFSILNANHFLSKEDIDYLRVNLPRSTAEEINNYLKKYECYSPLNNLELDDFE"
     gene            complement(5218..6024)
                     /gene="yidA"
                     /locus_tag="VQ543_000286"
     CDS             complement(5218..6024)
                     /gene="yidA"
                     /locus_tag="VQ543_000286"
                     /EC_number="3.1.3.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000023490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-phosphatase"
                     /protein_id="HET2611081.1"
                     /translation="MSIKLIAVDIDGTLVNSQKEITPEVFSAIQDAKEAGVKVVIATG
                     RPIAGVAKLLDDLQLRDQGDYVVTFNGALVQETATGHEIISESLTYEDYLDMEFLSRK
                     LGVHMHAITKDGIYTANRNIGKYTVHESTLVSMPIFYRTPEEMAGKEIVKCMFIDEPE
                     ILDAAIEKIPAEFYERYSINKSAPFYLELLKKNVDKGSAITHLAEKLGLTKDETMAIG
                     DEENDRPMLEVVGNPVVMENGNPEIKKIAKYITKTNDESGVAHAIRTWVL"
     gene            complement(6037..7341)
                     /locus_tag="VQ543_000287"
     CDS             complement(6037..7341)
                     /locus_tag="VQ543_000287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001003495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HET2611082.1"
                     /translation="MNEKVFRDPVHNYIHVNNQIIYDLINTKEFQRLRRIKQLGTSSY
                     TFHGGEHSRFSHCLGVYEIARRITEIFEEKYPEEWNPAESLLTVTAALLHDLGHGAYS
                     HTFENLFDTDHEAITQEIIQNPETEIHQVLLQVAPDFPEKVASVIDHTYPNKQVVQLI
                     SSQIDADRMDYLLRDSYFTGASYGEFDLTRILRVIRPVENGIAFQRNGMHAIEDYVLS
                     RYQMYMQVYFHPATRAMEVLLQNLLKRAKELYPEDKNFFARTSPHLLPFFEKNVTLTD
                     YLALDDGVMNTYFQLWMTSPDKILADLSQRFVNRKVFKSITFSQEDQDQLTSMRKLVE
                     DIGFDPDYYTAIHKNFDLPYDIYRPESQNPRTQIEILQKNGELAELSSLSPIVQSLAG
                     SRHGDNRFYFPKEMLDQNSIFASITQQFLHLIENDHFTPNKN"
     gene            7413..7790
                     /locus_tag="VQ543_000288"
     CDS             7413..7790
                     /locus_tag="VQ543_000288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1934 domain-containing protein"
                     /protein_id="HET2611083.1"
                     /translation="MKIRMRNTIQFDEQLEVIDQLYDVEVHEKGDYSYLLFYNEEKEK
                     VVIKFHGQELMMSRFSNPKTIMRFLKDSDSLAYIPTPMGMQEFIIQTSHYQVDRQKIE
                     LDYQLQNQEGHPFASYQLEITWG"
     gene            7881..8213
                     /locus_tag="VQ543_000289"
     CDS             7881..8213
                     /locus_tag="VQ543_000289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009660419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA-binding protein"
                     /protein_id="HET2611084.1"
                     /translation="MEIEKTNRMNALFEFYAALLTDKQMNYIELYYADDYSLAEIAEE
                     FGVSRQAVYDNIKRTEKILEDYEMKLHMYSDYIVRSQIFDQILERYPKDDFLQEQIEI
                     LTSIDNRE"
     gene            8225..9796
                     /gene="ffh"
                     /locus_tag="VQ543_000290"
     CDS             8225..9796
                     /gene="ffh"
                     /locus_tag="VQ543_000290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle protein"
                     /protein_id="HET2611085.1"
                     /translation="MAFESLTERLQNVFKNLRKKGKISESDVQEATKEIRLALLEADV
                     ALPVVKDFIKKVRERAVGHEVIDTLNPAQQIIKIVDEELTAVLGSDTAEIIKSPKIPT
                     IIMMVGLQGAGKTTFAGKLANKLKKEENARPLMIAADIYRPAAIDQLKTLGQQIDVPV
                     FALGTEVPAVEIVRQGLEQAQTNHNDYVLIDTAGRLQIDELLMNELRDVKALAQPNEI
                     LLVVDAMIGQEAANVAREFNAQLEVTGVILTKIDGDTRGGAALSVRHITGKPIKFTGT
                     GEKITDIETFHPDRMSSRILGMGDMLTLIEKASQEYDEQKALEMAEKMRENTFDFNDF
                     IDQLDQVQNMGPMEDLLKMIPGMANNPALQNMKVDERQIARKRAIVSSMTPEERENPD
                     LLNPSRRRRIAAGSGNTFVEVNKFIKDFNQAKQLMQGVMSGDMNKMMKQMGINPNNLP
                     KNMPNMGGMDMSALEGMMGQGGMPDLSALGGAGMPDMSQMFGGGLKGKIGEFAMKQSM
                     KRMANKMKKAKKKRK"
     gene            complement(9991..11274)
                     /locus_tag="VQ543_000291"
     CDS             complement(9991..11274)
                     /locus_tag="VQ543_000291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007554578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil permease"
                     /protein_id="HET2611086.1"
                     /translation="MKQESTVDLLLDVDQRPSAGKGILLSFQHVFAMFGATILVPLIL
                     GMPVSVALFASGVGTLIYMIATGFKVPVYLGSSFAFITAMSLAMKEMGGDVSAAQTGV
                     ILTGLVYVLVATSIRFVGTKWIDKLLPPIIIGPMIIVIGLGLAGSAVTNAGLVADGNW
                     KNALVAVVTFLIAAFINTKGKGFLRIIPFLFAIIGGYLFALTLGLVDFTPVLKANWFE
                     IPGFYLPFSTGGAFKEYNLYFGPEAIAILPIAIVTISEHIGDHTVLGQICGRQFLKEP
                     GLHRTLLGDGIATSVSAFLGGPANTTYGENTGVIGMTRIASVSVIRNAAFIAIALSFL
                     GKFTALISTIPNAVLGGMSILLYGVIASNGLKVLIKERVDFAQMRNLIIASAMLVLGL
                     GGAILKLGPVTLSGTALSAMTGIILNLILPYENKD"
     gene            complement(11577..12290)
                     /gene="rsmG"
                     /locus_tag="VQ543_000292"
     CDS             complement(11577..12290)
                     /gene="rsmG"
                     /locus_tag="VQ543_000292"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(527)-N(7))-methyltransferase
                     RsmG"
                     /protein_id="HET2611087.1"
                     /translation="MKPKTFYNLLAEQNLPLSDQQKEQFERYFELLVEWNEKINLTAI
                     TDKEEVYLKHFYDSIAPILQGLIPNETIKLLDIGAGAGFPSLPMKILYPELDVTIIDS
                     LNKRINFLQLLAQELDLNGVHFYHGRAEDFAQDKNFRAQYDFVTARAVARMQVLSELT
                     IPYLKVGGKLLALKASNAPEELLEAKNALNLLFSKVEDNLSYALPNRDPRYITVVEKK
                     KETPNKYPRKAGMPNKRPL"
     gene            12384..12944
                     /locus_tag="VQ543_000293"
     CDS             12384..12944
                     /locus_tag="VQ543_000293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LemA family protein"
                     /protein_id="HET2611088.1"
                     /translation="MTWIILGVIALIVIFVIVSYNGLVKNRMQTKEAWSQIDVQLKRR
                     NDLLPNLIETVKGYAKYEGSTLEKVAELRNQVAAATSPAEAMKASDALTRQVSGIFAV
                     AESYPDLKASANFVKLQEELTNTENKISYSRQLYNSVVSNYNVKLETFPSNIIAGMFG
                     FKAADFLQTSEEEKSVPKVDFSGLGD"
     gene            12946..13845
                     /gene="htpX"
                     /locus_tag="VQ543_000294"
     CDS             12946..13845
                     /gene="htpX"
                     /locus_tag="VQ543_000294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metalloprotease HtpX"
                     /protein_id="HET2611089.1"
                     /translation="MLFDQIASNKRKTWILLLVFFLLLALVGYAVGYLFIRSGLGGLV
                     IALIIGFIYALSMIFQSTEIVMSMNGAREVDEQTAPDLYHVVEDMALVAQIPMPRVFI
                     IDDPALNAFATGSNPQNAAVAATSGLLAIMNREELEAVMGHEVSHIRNYDIRISTIAV
                     ALASAITMLSSMAGRMMWWGGAGRRRSDDDRDGNGLEIIMLVVSLLAIVLAPLAATLV
                     QLAISRQREFLADASSVELTRNPQGMINALDKLDNSKPMSRHVDDASSALYINDPKKG
                     GGFQKLFYTHPPISERIERLKQM"
     gene            complement(13889..15448)
                     /locus_tag="VQ543_000295"
     CDS             complement(13889..15448)
                     /locus_tag="VQ543_000295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011681787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HET2611090.1"
                     /translation="MHYRHSRKGNSMIKINHLTITQNKDLRDLVSDLSMTIQDGEKVA
                     IIGEEGNGKSTLLKTLMGEDLSDFTIKGDIQSDYQSLAYIPQKVPEDLKKKTLHDYFF
                     LDSIDLDYSILYRLAEELHFDSNRFASDQEIGNLSGGEALKIQLIHELAKPFEILFLD
                     EPSNDLDLETVDWLKGQIQKTRQTVIFISHDEDFLSETADTIVHLRLVKHRKEAETLV
                     EHLDYDSYSEQRKANFAKQSQQAANNQRAYDKTMEKHRRVKQNVETALRATKDSTAGR
                     LLAKKMKTVLSQEKRYEKTAQSMTQKPLEEEQIQLFFSDIQPLPASKVLVQLEKENLS
                     IDDRVLAQELQLTVRGQEKIGIIGPNGVGKSTLLAKLQQLLNDKREISLGFMPQDYHK
                     KLQLDLSSIAYISKTGEKEELQKIQSHLASLNFSYPEMQHQIRSLSGGQQGKLLLLDL
                     VLRKPNFLLLDEPTRNFSPTSQPQIRKLFATYPGGLITVSHDRRFLKEVCSIIYRMTE
                     HGLKLVNLEDL"
     gene            complement(15687..16004)
                     /locus_tag="VQ543_000296"
     CDS             complement(15687..16004)
                     /locus_tag="VQ543_000296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000389556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase BlpT"
                     /protein_id="HET2611091.1"
                     /translation="MEDKKLIQLLSKLNKSYQNCKQGTADDIRLQELLNTTMQELKKT
                     EKLNNSILIDLEKFYQPTSPLIGLGSLKLNDQARTAWRNYDKIHYEHVKHVLSLYGPV
                     FGF"
     gene            16183..16725
                     /locus_tag="VQ543_000297"
     CDS             16183..16725
                     /locus_tag="VQ543_000297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF177 domain-containing protein"
                     /protein_id="HET2611092.1"
                     /translation="MKLNIQEIRKQSEGLNFEQTLDLVDDLRARNQEILDVKDILAVG
                     KVQYEDRMYFLDYQLSYTIVLASSRSMEPVELVESYPVTEVFMEGATNQLDQEVLDDD
                     LVLPIENGELDLAESVSDNILLNIPIKVLTAEEEAGQGFISGNDWQIMTEEEYQAQQA
                     VKKEENSPFAGLQGLFDGDE"
     gene            16725..17354
                     /gene="nth"
                     /locus_tag="VQ543_000298"
     CDS             16725..17354
                     /gene="nth"
                     /locus_tag="VQ543_000298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000244461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease III"
                     /protein_id="HET2611093.1"
                     /translation="MVLSKKRARKVLEEIIALFPDAKPSLDFTNHFELLVAVMLSAQT
                     TDAAVNKATPGLFVAFPTPQAMSVATESEIASHISRLGLYRNKAKFLKKCAQQLLDDF
                     DGQVPQTREELESLAGVGRKTANVVMSVGFGIPAFAVDTHVERICKHHDIVKKSATPL
                     EVEKRVMDILPPEQWLAAHQAMIYFGRAICHPKNPECDQYPQLYDFSNL"
     gene            17565..18086
                     /gene="pyrR"
                     /locus_tag="VQ543_000299"
     CDS             17565..18086
                     /gene="pyrR"
                     /locus_tag="VQ543_000299"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional pyr operon transcriptional
                     regulator/uracil phosphoribosyltransferase PyrR"
                     /protein_id="HET2611094.1"
                     /translation="MKTKEVVDELTVKRAITRITYEIIERNKDLNKIVLAGIKTRGVF
                     IAHRIQERLKQLENLSVPVVELDTKPFRDDVKSGEDTSLVSVDVTDREVILVDDVLYT
                     GRTIRAAIDNIVGHGRPARVSLAVLVDRGHRELPIRPDYVGKNIPTSRSEEIIVEMTE
                     LDDQDRVLITEEA"
     gene            18105..19028
                     /locus_tag="VQ543_000300"
     CDS             18105..19028
                     /locus_tag="VQ543_000300"
                     /EC_number="2.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001293822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase catalytic
                     subunit"
                     /protein_id="HET2611095.1"
                     /translation="MSENQQALNHVVSMEDLTVDQVMKLIKRGIEFKNGAQLPYEDHP
                     IVSNLFFEDSTRTHKSFEVAEIKLGLERLDFDVKTSSVNKGETLYDTILTLSALGVDV
                     CVIRHPEVDYYRELIASPTITTSIINGGDGSGQHPSQSLLDLMTIYEEFGHFEGLKVA
                     IAGDLDHSRVAKSNMQILKRLGAELFFAGPEEWRSQEFADYGKFVTIDEIIDQVDVMM
                     FLRVQHERHDSGAVFSKEDYHAQHGLTQERYDRLKETAILMHPAPINRDVEIADHLVE
                     APKSRIVQQMTNGVFVRMAILESVLASRNAN"
     gene            19078..20157
                     /gene="carA"
                     /locus_tag="VQ543_000301"
     CDS             19078..20157
                     /gene="carA"
                     /locus_tag="VQ543_000301"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing carbamoyl-phosphate
                     synthase small subunit"
                     /protein_id="HET2611096.1"
                     /translation="MTKRILVLEDGTVFEGKAFGADIDVTGEIVFNTGMTGYQESITD
                     QSYNGQILTFTYPLVGNYGINRDDYESIIPTCKGVVVFEEARRASNWRNQMTLDEFLK
                     AKKIPGISGIDTRALTKIIRKHGTMRATLTHVGDSMDHVTDQLQATVLPTDNIKQVST
                     KTSYPAPGVGLSVVLVDFGLKHSILRELSKRNCNVTVVPYSTTAEEILHLNPDGVMLS
                     NGPGNPEDVPQALDMIRGVQGKIPIFGICMGHQLFAMANGAKTYKMKFGHRGFNHAVR
                     EIATGRVDFTSQNHGYAVSREDLPEHLIITHEEINDKSVEGVRHRYQPAFSVQYHPDA
                     APGPHDASYLFDEFIEMMEVFKQSN"
     gene            20469..23645
                     /gene="carB"
                     /locus_tag="VQ543_000302"
     CDS             20469..23645
                     /gene="carB"
                     /locus_tag="VQ543_000302"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019803305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="HET2611097.1"
                     /translation="MPKRTDIQKIMVIGSGPIIIGQAAEFDYAGTQACLSLKEEGYEV
                     VLVNSNPATIMTDKEIADKVYIEPITLEFVTRILRKERPDALLPTLGGQTGLNMAMEL
                     SKNGILDELGVELLGTKLSAIDQAEDRDLFKQLMEELEQPIPESEIVNTVEEAVAFAA
                     TIGYPVIVRPAFTLGGTGGGMCANEKELREITENGLKLSPVTQCLIERSIAGFKEIEY
                     EVMRDSADNALVVCNMENFDPVGIHTGDSIVFAPAQTMSDYENQMLRDASLSIIRALK
                     IEGGCNVQLALDPNSFKYYVIEVNPRVSRSSALASKATGYPIAKLAAKIAVGLTLDEV
                     INPVTGSTYAMFEPALDYVVAKIPRFPFDKFEKGERRLGTQMKATGEVMAIGRNIEES
                     LLKACRSLEIGVHHNEIPELAAVSDDALIEKVVKAQDDRLFYVSEAIRRGYTPEEIAE
                     LTKIDIFYLDKLLHIFEIEQELGAHPQDLEVLKTAKLNGFSDRKIAELWGTTDDQVRQ
                     LRLENKIVPVYKMVDTCAAEFDSETPYFYSTYGWENESIRSDKESVLVLGSGPIRIGQ
                     GVEFDYATVHSVKAIQAAGYEAIIMNSNPETVSTDFSVSDKLYFEPLTFEDVMNVIDL
                     EQPKGVIVQFGGQTAINLAEPLAKAGVTILGTQVADLDRAEDRDLFEQALKELDIPQP
                     PGQTATNEEEAALAARKIGFPVLVRPSYVLGGRAMEIVENEEDLRSYMRTAVKASPDH
                     PVLVDSYIVGQECEVDAISDGKNVLIPGIMEHIERAGVHSGDSMAVYPPQTLSQKVQE
                     TIADYTKRLAIGLHCLGMMNIQFVIKDEKVYVIEVNPRASRTVPFLSKVTNIPMAQVA
                     TKLILGQSLSELGYQNGLYPESTRVHIKAPVFSFTKLAKVDSLLGPEMKSTGEVMGSD
                     ATLEKALYKAFEASYLHLPTFGNVVFTIADDAKEEALNLARRFQNIGYGILATEGTAA
                     FFASHGLQAQPVGKIGDDDKDIPSFVRKGRIQAIINTVGTKRTADEDGEQIRRSAIEH
                     GVPLFTALDTANAMLKVLESRSFVTEAI"
     gene            complement(23920..24729)
                     /locus_tag="VQ543_000303"
     CDS             complement(23920..24729)
                     /locus_tag="VQ543_000303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001199643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HET2611098.1"
                     /translation="MQYLEKKEIKEIQLALLDYIDETCKKHDIPYFLSYGTMLGAIRH
                     KGMIPWDDDIDISLYREDYERLLKIIEEENHPRYKVLSYDTSSWYFHNFASILDTSTV
                     IEDHVKYKRHDISLFIDVFPIDQFTDLSIVDKSYKYVALRQLAYIKKSRAVHGDSKLK
                     DFLRLCSWYALRFVNPRYFYKKIDQLVKNAVTNIPQYEGGVGIGKEGMKEIFPVDTFK
                     ELILTEFEGRMLPVPKKYDQFLTQMYGDYMTPPSKEMQEWYSHSIKAYRKN"
     gene            complement(24731..25534)
                     /locus_tag="VQ543_000304"
     CDS             complement(24731..25534)
                     /locus_tag="VQ543_000304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HET2611099.1"
                     /translation="MKQLTVEDAKQIELEILNYIDTLCKKHNINYIINYGTLIGAVRH
                     EGFIPWDDDIDLSMPREDYQRFINIFQKEKSKYKLLSLETDKNYFNNFIKITDSTTKI
                     IDTRNTKTYESGIFIDIFPMDRFDDPKVIDTCYKLESFKLLSFSKHKNIVYKDSLLKD
                     WIRTAFWLLLRLVSPRYFANKIEKEIQKYSRENGQYMAFIPSKFKEKEVFPSATFDKT
                     IDLPFENLSLPAPEKFDTILTQFYGDYMTLPPEEKRFYSHEFHAYKLED"
     gene            complement(25544..27031)
                     /gene="tacF"
                     /locus_tag="VQ543_000305"
     CDS             complement(25544..27031)
                     /gene="tacF"
                     /locus_tag="VQ543_000305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV teichoic acid flippase TacF"
                     /protein_id="HET2611100.1"
                     /translation="MKSIKLNALSYMGIRVLNIIFPILTGTYVARVLDRTDYGYFNSV
                     DTILSFFLPFATYGVYNYGLRAISNVKDNKKDLNRTFSSLFYLCIACTILTTAVYILA
                     YPLFFTDNPIVKKVYLVMGIQLIAQIFSIEWVNEALENYSFLFYKTAFIRILMLVSIF
                     LFVKNEHDIVVYTLVMSLSTLINYLISYFWIKRDIKLVKIHLSDFKPLFLPLTAMLVF
                     ANANMLFTFLDRLFLVKTGIDVNVSYYTIAQRIVTVIAGVVTGAIGVSVPRLSYYLGK
                     GDKEAYVSLVNRGSRIFNFFIIPLSFGLMVLGPNAILLYGSEKYIGGDILTSLFAFRT
                     IILALDTILGSQILFTNGYEKRITVYTVFAGLLNLGLNSLLFFNHIVAPEYYLLTTML
                     SEASLLVFYIIFIHRKQLIHLGHIFSYTVRYSLFSLSFVAIYFLINFVYPVDMVINLP
                     FLINTGLIVLLSAISYISLLVFTKDSIFYEFLNHVLALKNKFKKS"
     gene            27367..28074
                     /locus_tag="VQ543_000306"
     CDS             27367..28074
                     /locus_tag="VQ543_000306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-C-methyl-D-erythritol 4-phosphate
                     cytidylyltransferase"
                     /protein_id="HET2611101.1"
                     /translation="MIYAGILAGGTGTRMGISNLPKQFLELGDRPILIHTIEKFVLEP
                     SIEKIVVGVHGDWVSHAEDLVDKYLPLYKERIIITKGGADRNTSIKKIIEAIDAYRPL
                     TPEDIVVTHDSVRPFITLRMIQDSIQLAQNHDAVDTVVEAVDTIVESTNGQFITDIPN
                     RAHLYQGQTPQTFRCKDFMDLYGSLSDEEKEILTDACKIFVIKGKDVALAKGEYSNLK
                     ITTVTDLKIAKSMIEKD"
     gene            28079..29101
                     /locus_tag="VQ543_000307"
     CDS             28079..29101
                     /locus_tag="VQ543_000307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase catalytic
                     domain-containing protein"
                     /protein_id="HET2611102.1"
                     /translation="MINQIYQLTKPKFINVKYQEEAIDQENHILIRPNYMAVCHADQR
                     YYQGKRDPKILNKKLPMAMIHESCGTVISDPTGTYEVGQKVVMIPNQSPMQSDEEFYE
                     NYMTGTHFLSSGFDGFMREFVSLPKDRVVAYDAIEDTVAAITEFVSVGMHAMNRLLTL
                     AHSKRERIAVIGDGSLAFVVANIINYTLPEAEIVVIGRHWEKLELFSFAKECYITDNI
                     PEELAFDHAFECCGGDGTGPAINDLIRYIRPQGTILMMGVSEYKVNLNTRDALEKGLI
                     LVGSSRSGRIDFKNAIQMMEVKKFANRLKNILYLEEPVREIKDIHRVFATDLNTAFKT
                     VFKWEV"
     gene            29118..29987
                     /gene="licA"
                     /locus_tag="VQ543_000308"
     CDS             29118..29987
                     /gene="licA"
                     /locus_tag="VQ543_000308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000411210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline kinase LicA"
                     /protein_id="HET2611103.1"
                     /translation="MEKIIKEKISSLLSQEEEVLSVEQLGGMTNQNYLAKTTNKQYIV
                     KFFGKGTEKLINRQDEKYNLELLKDLGLDVKNYLFDIEAGIKVNEYIESAITLDSTSI
                     KTKFDKIAPILQTIHTSAKELRGEFAPFEEIKKYESLIEEQIPYANYESVRNAVFSLE
                     KRLADLGVDRKSCHIDLVPENFIESPQGRLYLIDWEYSSMNDPMWDLAALFLESEFTS
                     QEEETFLSHYESDQTPVSHEKIAIYKILQDTIWSLWTVYKEEQGEDFGDYGVNRYQRA
                     VKGLASYGGSDEK"
     gene            29977..30855
                     /locus_tag="VQ543_000309"
     CDS             29977..30855
                     /locus_tag="VQ543_000309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000837620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HET2611104.1"
                     /translation="MKSKNGVPFGLLSGIFWGLGLTVSAYIFSIFTDLSPFVVAAAHD
                     FLSIFILLAFLLVKEGKVRLSIFLNIRNVSVIIGALLAGPIGMQANLYAVKYIGSSLA
                     SSVSAIYPAISVLLAFFFLKHKISKNTVFGIVLIIGGIIAQTYKVEQVNSFYIGILCA
                     LVCAIAWGSESVLSSFAMESELSEIEALLIRQVTSFLSYLVIVLFSHQSFTAVANGQL
                     LGLMIVFAAFDMISYLAYYIAINRLQPAKATGLNVSYVVWTVLFAVVFLGAPLDMLTI
                     MTSLVVIAGVYIIIKE"
     gene            30867..31556
                     /locus_tag="VQ543_000310"
     CDS             30867..31556
                     /locus_tag="VQ543_000310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NTP transferase domain-containing protein"
                     /protein_id="HET2611105.1"
                     /translation="MKAIILAAGLGTRLRPMTENTPKALVQVNQKPLIEYQIEFLKEK
                     GINDIIIIVGYLKEQFDYLKEKYGVRLVFNDKYADYNNFYSLYLVKEELANSYVIDAD
                     NYLFKNMFRNDLTRSTYFSVYREDCTNEWFLVYGDDYKVQNIIVDSKAGRILSGVSFW
                     DAPTAEKIVSFIDKAYASGEFVDLYWDNMVKDNIKELDVYVEELEGNSIYEIDSVQDY
                     HKLEEILKNEN"
     gene            31654..32502
                     /gene="dprA"
                     /locus_tag="VQ543_000311"
     CDS             31654..32502
                     /gene="dprA"
                     /locus_tag="VQ543_000311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-protecting protein DprA"
                     /protein_id="HET2611106.1"
                     /translation="MKITNYEIYKLKKSGLTNQQILKVLEYGENVDQELLLGDIADIS
                     GCRNPAVFMERYFQIDDAHLSKEFQKFPSFSILDDCYPWDLSEIYDAPVLLFYKGNLD
                     LLKFPKVAVVGSRACSKQGAKSVEKVIQGLENELVIVSGLAKGIDTAAHMAALQNGGK
                     TIAVIGTGLDVFYPKANKRLQDYIGNDHLVLSEYGPGEQPLKFHFPARNRIIAGLCRG
                     VIVAEAKMRSGSLITCERAMEEGRDVFAIPGSILDGLSDGCHHLIQEGAKLVTSGQDV
                     LAEFEF"
     gene            33386..34429
                     /locus_tag="VQ543_000312"
     CDS             33386..34429
                     /locus_tag="VQ543_000312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00341 family protein"
                     /protein_id="HET2611107.1"
                     /translation="MTNNKLYSLIEFRNKIYEELELSRSDLAILLCAMLIASIGLNMD
                     STPVIIGAMLISPLMTPILGVGLSLAIFDFKLLRKSFKILAIQILASLIASTLYFYLS
                     PISYASSEIVARTSPTIWDVLIAFVGGIAGIIGARKKETNNIVPGVAIATALMPPLCT
                     VGYAIASANLKFIIGSSYLFLINCSFIVIATYIGVRLMMVKKHYFKDNEEDSKMRRIL
                     LLVAVLLMIPSFISATTLVRETLKKESLKKFISEQFQGHNILKKTYSKKTHTLKLTIS
                     GNYLTEEELDMISSKRGDYGLSDVSVQVSQLSDSEQLSKEELVEYFFQYIKDKEAKEK
                     EKANKFYTESEEQ"
     gene            34596..36683
                     /gene="topA"
                     /locus_tag="VQ543_000313"
     CDS             34596..36683
                     /gene="topA"
                     /locus_tag="VQ543_000313"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I DNA topoisomerase"
                     /protein_id="HET2611108.1"
                     /translation="MATATKKKKSTVKKNLVIVESPAKAKTIEKYLGRNYKVLASVGH
                     IRDLKKSSMSVDIENNYEPQYINIRGKGPLINDLKKEAKKANKVFLASDPDREGEAIS
                     WHLAHILNLDENDANRVVFNEITKDAVKNAFKEPRKIDMDLVDAQQARRILDRLVGYS
                     ISPILWKKVKKGLSAGRVQSIALKLIIDRENEINAFQPEEYWTVDAVFKKGTKQFHAS
                     FYGVDGKKMKLTSNDEVKEVLSRLTSKDFSVDQVDKKERKRNAPLPYTTSSMQMDAAN
                     KINFRTRKTMMVAQQLYEGINIGSGVQGLITYMRTDSTRISPVAQNEAASFITDRFGS
                     KYSKHGSKVKNASGAQDAHEAIRPSSVFNTPESIAKYLDKDQLKLYTLIWNRFVASQM
                     TAAVFDTMAVKLSQNGVQFAANGSQVKFDGYLAIYNDSDKNKMLPDMVVGDVVKQVNS
                     KPEQHFTQPPARYSEATLIKTLEENGVGRPSTYAPTIETIQKRYYVRLAAKRFEPTEL
                     GEIVNKLIVEYFPDIVNVTFTAEMEGKLDDVEVGKEQWRRVIDAFYKPFSKEVAKAEE
                     EMEKIQIKDEPAGFDCEVCGSPMVIKLGRFGKFYACSNFPDCRHTQAIVKEIGVECPS
                     CHQGQIIERKTKRNRLFYGCNRYPECEFTSWDKPVGRDCPKCGNFLMEKKVRGGGKQV
                     VCSKGDYEEEKIK"
     gene            36904..37263
                     /locus_tag="VQ543_000314"
     CDS             36904..37263
                     /locus_tag="VQ543_000314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaN family protein"
                     /protein_id="HET2611109.1"
                     /translation="MRIIYLIIGFLSLTLAIVGVVLPLLPTTPFLLLSIACFSRSSKR
                     FEDWLYHTKLYQAYVADFRETKSIARERKKKIIVSIYVLMGISIYFAPLLPVKIGLGA
                     LTIFITYYLFKVIPDKE"
     gene            37356..37988
                     /locus_tag="VQ543_000315"
     CDS             37356..37988
                     /locus_tag="VQ543_000315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000638771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper homeostasis protein CutC"
                     /protein_id="HET2611110.1"
                     /translation="MIYEFCAENVTLLEKAMQAGARRIELCDNLAVGGTTPSYGVTKA
                     AVELAANYDTTIMTMIRPRGGDFVYNDLEIAIMLEDIRLTAQAGSQGVVFGALTADKK
                     LDKPNLEKLIAASKGMEIVFHMAFDELSDEDQPEAIDWLSQAGVTRILTRAGVSGDSL
                     EKRFVHYHRILEYAKGKIEILPGGGIDLENRQTFIDQVGVTQLHGTKVVF"
     gene            38032..38688
                     /locus_tag="VQ543_000316"
     CDS             38032..38688
                     /locus_tag="VQ543_000316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000461593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MmcQ/YjbR family DNA-binding protein"
                     /protein_id="HET2611111.1"
                     /translation="MFEIFKSYQFNQEKAHDYGFIENSEVWTYSCQILQGDFVMTVSI
                     TADNVNFQVFDQETGDLYPHVYMESMRGSFVGNVREACLEILYQIRKACFDVQDFICH
                     QTKRIMTQVQEKYGNQLEYLWEKSPDTAVLRHEGNQKWYAVLMKISWNKLEKGREGQV
                     EAVNLKHDQVANLLSQKGIYPAFHMSKRYWISVSLDDTLSDEEVLELIEKSWNLTSKK
                     "
     gene            38707..39801
                     /locus_tag="VQ543_000317"
     CDS             38707..39801
                     /locus_tag="VQ543_000317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001010962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-isopropylmalate synthase"
                     /protein_id="HET2611112.1"
                     /translation="MNFQLAKYSLLKRFLENIGFTTLEEYGAIFKYLIENVKTDRQII
                     YSPHCHDDLGMAVANSLAAVKNGAGRVEGTINGIRERAENAALEEIAVALNIRQDYYQ
                     VETSIVLNETINTSEMVSRFSGIPVPKNKAVVGGNTFSHESGIHQDGVLKNPLTYEII
                     TPELVGVKILLGKLSGRHAFVEKLRELALDFTEEDIKPLFAKFKALVDKKQEITDADI
                     RALVAGTMVENPEGFHFDDLQLQTHADNDIEALVSLANMDGEKVEFNATGQGSVEAIF
                     NAIDKFFNQSVRLVSYTIDAVTDGIDTQDRVLVTVENRDTETIFNAAGLDFDVLKASA
                     IVYINANTFVQKENAGEMGRSVSYHDMPSV"
     gene            39813..40850
                     /gene="leuB"
                     /locus_tag="VQ543_000318"
                     /pseudo
     CDS             39813..40850
                     /gene="leuB"
                     /locus_tag="VQ543_000318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399454.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydrogenase"
     gene            40847..41116
                     /locus_tag="VQ543_000319"
     CDS             40847..41116
                     /locus_tag="VQ543_000319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1294 domain-containing protein"
                     /protein_id="HET2611113.1"
                     /translation="MKLDEKITLVLLIWNVIIFLIYGIDKSKARRRVWRIPEKILLIL
                     AFTFGGFGAWLAGIIFHHKTRKWYFKIVWFLGMVTTLVALYFIWR"
     gene            41120..41479
                     /gene="leuD"
                     /locus_tag="VQ543_000320"
     CDS             41120..41479
                     /gene="leuD"
                     /locus_tag="VQ543_000320"
                     /EC_number="4.2.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydratase small subunit"
                     /protein_id="HET2611114.1"
                     /translation="MAGSSREYAAWALADYGFKVVIAGSFGDIHYNNELNNGMLPIVQ
                     PREVREKLAQLKPTDQVTVDLEQQKIISPVEEFTFEIDSEWKHKLLNSLDDIGITLQY
                     EELIAAYEKQRPAYWQD"
     gene            41641..42209
                     /locus_tag="VQ543_000321"
                     /pseudo
     CDS             41641..42209
                     /locus_tag="VQ543_000321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019771122.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="translation factor (SUA5)"
     gene            42303..42368
                     /locus_tag="VQ543_000322"
                     /pseudo
     CDS             42303..42368
                     /locus_tag="VQ543_000322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849983.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="translation factor (SUA5)"
     gene            42531..44462
                     /locus_tag="VQ543_000323"
     CDS             42531..44462
                     /locus_tag="VQ543_000323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="McrB family protein"
                     /protein_id="HET2611115.1"
                     /translation="MNKRKVSLEDFYKWYSLNKEELLNKATVGEKFNDKLKEEFLQEW
                     PLDRILTMSIDEYVIGKGQQNKSLCYALEKGKYKNLFLGISGGSASKFGIYWNKKTNK
                     YKDQANNEISELDQRFSKLKSDLYEIIKEGIRFNFENPIFDMKRSTNEFIGRSAMVTK
                     LLCIYTEGDPFFGVNINSQKEFWNHFVSQTNQGGPYLQNHKIIELMSKTYPELEPSKL
                     GTMLFEYSKLFMENKEDNSTMDSSNNFRHQLTQSLLKSPNLILRGAPGTGKTYLAKEI
                     AKELTDGNEDQIGFVQFHPSYDYTDFVEGLRPVSNGDGAIEFRLQDGIFKDFCQKAKE
                     TQLIGGQDNFDEAWDSYLEYINVAEEKEYITKTSYLSVNSRQNLSVNYDSGVPGWSLP
                     SKYVYELYKDKNYNKQEYYKSGGKTVLETLRKRFGLKDYVSPTEIDTDKKFVFIIDEI
                     NRGEISKIFGELFFSIDPGYRGEKGSVSTQYANLHETDEKFYIPENVYIIGTMNDIDR
                     SVDTFDFAMRRRFRFVEVTAEGQVGMLDKELNIHAEEAKIRLRNLNAAIENVQELNSH
                     YHIGPSYFLKLKDVDFDYELLWSDYIKPLLEDYLRGSYDEVETLETLKKAFELTNNEQ
                     KDQAVADDNESDENDDADY"
     gene            44449..45801
                     /locus_tag="VQ543_000324"
     CDS             44449..45801
                     /locus_tag="VQ543_000324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001223073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="McrC family protein"
                     /protein_id="HET2611116.1"
                     /translation="MRITDNQHKIIKEKFVEEYPKLSNLLLDRTLESLSQDERIFIFP
                     NDLTHTPDLDKKQKILETINQEIKTGNVIGFLGYGQERLTISSRFSDESNDHFLHYLL
                     NKVLHINLTSLDVALSREERLYQLLMYLFPKYLQAAIRKGLYKEYHRFSHNDSHVKGV
                     IDVRNHLKKNLPFTGNIAYTTREFTYDNPLMQLVRHTIEYIKNQKSIGQGVLDNLSTS
                     RENVSEIVRVTPSYKLADRAKIIRGNQSKPIRHAYFHEYRNLQELCLMILNQEKHGLG
                     YQDQKIYGILFDVAWLWEEYVYTLLPKGFVHPRNKDKTDGISVFSVGKRKVYPDFYDR
                     ERKIVLDAKYKKLELTEKGINREDLFQLISYSYILKAEKAGLVFPSKDKVIDNEMGNL
                     AGYGALLKKWSIQIPQKSSSYSAFCKMMENSDYSAFCKMMENSEENFKAIIDEEVGRK
                     "
     gene            45976..46962
                     /locus_tag="VQ543_000325"
     CDS             45976..46962
                     /locus_tag="VQ543_000325"
                     /EC_number="1.7.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007516839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GMP reductase"
                     /protein_id="HET2611117.1"
                     /translation="MLNEFPIFDYEDIQLIPNKCVIKSRAEADTSVTLGNHTFKLPVV
                     PANMQTILDENVAEQLAKGGYFYIMHRFDEAGRIPFIKQMHDQGLIASISVGVKDYEY
                     DFVSQLKTDAPEYITIDIAHGHADSVISMIQHIKKELPDTFVIAGNVGTPEAVRELEN
                     AGADATKVGIGPGKVCITKVKTGFGTGGWQLAALRWCAKAARKPIIADGGIRTHGDIA
                     KSIRFGASMIMIGSLFAGHIESPGKTIEVDGEQFKEYYGSASQYQKGAYKNVEGKRIL
                     LPAKGHLQDTLTEMEQDLQSAISYAGGRQVADLKHVDYVIVKNSIWNGDASH"
     gene            47026..47097
                     /locus_tag="VQ543_000326"
     tRNA            47026..47097
                     /locus_tag="VQ543_000326"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:47059..47061,aa:Arg,seq:ccg)
     gene            47280..47978
                     /locus_tag="VQ543_000327"
     CDS             47280..47978
                     /locus_tag="VQ543_000327"
                     /EC_number="3.1.26.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III"
                     /protein_id="HET2611118.1"
                     /translation="MKELQTVLKNHFAIEFADKNLLETAFTHTSYANEHRLLKISHNE
                     RLEFLGDAVLQLLISEYLYKKYPKKPEGDLSKLRAMIVREESLAGFARDCQFDQFIKL
                     GKGEEKSGGRNRDTILGDAFEAFLGALLLDKDVAKVKEFIYQVMIPKVEAGEFEMITD
                     YKTHLQELLQVNGDVAIRYQVISETGPAHDKVFDVEVLVEGKSIGQGQGRSKKLAEQE
                     AAKNAVEKGLDSCI"
     gene            47969..51508
                     /gene="smc"
                     /locus_tag="VQ543_000328"
     CDS             47969..51508
                     /gene="smc"
                     /locus_tag="VQ543_000328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000280891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein SMC"
                     /protein_id="HET2611119.1"
                     /translation="MYLKEIEIQGFKSFADKTKVVFDQGVTAVVGPNGSGKSNITESL
                     RWALGESSVKSLRGGKMPDVIFAGTESRKPLNYASVVVTLDNHDGFIKDAGQEIRVER
                     HIYRSGDSEYKIDGKKVRLRDIHDLFLDTGLGRDSFSIISQGKVEEIFNSKSEERRAI
                     FEEAAGVLKYKTRRKETESKLQQTQDNLDRLEDIIYELDNQIKPLEKQAENARKFLDL
                     EGQRKAIYLDVLVAQIKENKAELESTEEELAQVQELLMSYYQKREKLEEENQTLKKQR
                     QDLQAEMAKDQGSLMDLTSLISDLERKLALSKLESEQVALNQQEAQARLAALEDKRNS
                     LSKEKSDKESSLALLEGNLVQNNQKLNRLEAELLAFSDDPDQMIELLRERFVALLQEE
                     ADVSNQLTRIENELENSRQLSQKQADQLEKLKEQLAIAKEKASQQKEELETAKEQVQK
                     LLADYQAIAKEQEEQKTSYQAQQSQLFDRLDNLKNKQARAQSLENILRNHSNFYAGVK
                     SVLQEKDRLGGIIGAVSEHLTFDMHYQTALEIALGASSQHIIVEDEESATKAIDFLKR
                     NRAGRATFLPLTTIKARTISSQNQDAITVSPGFLGMADELVTFDTRLEAIFKNLLATT
                     AIFDAVEHARAAARQVRYQVRMVTLDGTELRTGGSYAGGANRQNNSIFIKPELEQLQK
                     EIAADEASLRSEEAALKTLQDQMATLTERLEVIKSQGEQARIQEQGLSLAYQQTSQQV
                     EELETLWKLQEEEIDRLSEGDWQADKEKCQDRLAAIASDKQNLEAEIEEIKSNKNAIQ
                     ERYQNLQEELAQARLLKTELQGQKRYEVADIERLGKELDNLDFEQEEIQRLLQEKVDN
                     LEKVDTELLSQQAEEAKTQKTNLQQGLIRKQFELDDIEGQLDDIASHLDQARQQNEEW
                     IRKQTRAEAKKEKVSERLRYLQSQLTDQYQISYTEALEKAHELENLNLAEQEVQDLEK
                     AIRSLGPVNIEAIDQYEEVHNRLDFLNSQRDDILSAKNLLLETITEMNDEVKDRFKST
                     FEAIRESFKVTFKQMFGGGQADLILTEGDLLTAGVEISVQPPGKKIQSLNLMSGGEKA
                     LSALALLFSIIRVKTIPFVILDEVEAALDEANVKRFGDYLNRFDKDSQFIVVTHRKGT
                     MAAADSIYGVTMQESGVSKIVSVKLKDLESIEG"
     gene            51505..52299
                     /locus_tag="VQ543_000329"
     CDS             51505..52299
                     /locus_tag="VQ543_000329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000153012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HET2611120.1"
                     /translation="MTIKLVATDMDGTFLDGNGRFDMDRLKSLLASYKEKGIYFAVAS
                     GRGFLSLEKLFAGVRDDIIFIAENGSLVEYQGQDLYEATMSRDFYLATFEKLKTSPYV
                     DINKLLLTGKKGSYVLDTVDETYLKVSQHYNENIQKVASLEDITDDIFKFTTNFTEET
                     LEAGETWVNDNVPGVKAMTTGFESIDIVLDYVDKGVAIVELAKKLGITMDQVMAFGDN
                     LNDLHMMQVVGHPVAPENARPEILELAKTVIGHHKDQSVIAYMEGL"
     gene            52299..53117
                     /locus_tag="VQ543_000330"
     CDS             52299..53117
                     /locus_tag="VQ543_000330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HET2611121.1"
                     /translation="MADIKLIALDLDGTLLTTDKRLTDRTKATLKAASDRGIKVVLTT
                     GRPLKAMDFFLHELGTDGHEDEYTITFNGGLVQKNTGEILDKTVFSYDDVARLYEETE
                     KLSLPLDAISEGTVYQIQSDQESLYAKFNPALTFVPVDFEDLSSQMTYNKCVTAFAQE
                     PLDAAIQKISPELFDQYEIFKSREMLLEWSPKNVHKATGLAKLISHLGIDQSQVMACG
                     DEANDLSMIEWAGLGVAMQNAVPEVKAAANVVTPMTNDEEAVAWAIEEYVLKEN"
     gene            53121..54341
                     /gene="ftsY"
                     /locus_tag="VQ543_000331"
     CDS             53121..54341
                     /gene="ftsY"
                     /locus_tag="VQ543_000331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000522312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle-docking protein
                     FtsY"
                     /protein_id="HET2611122.1"
                     /translation="MGLFDRLFGKKEEPKIEEVVKEALENLDLSEDVDPTFTEVEEVS
                     QEEAVLEESQDSEPAVGVSQEEIEELPEEEKLEHEGTIEENNSEVLEAERPQTEETVQ
                     EKYDRSLKKTRTGFGARLNAFFANFRSVDEEFFEELEELLIMSDVGVQVASNLTEELR
                     YEAKLENAKKPDALRRVIIEKLVELYEKDGSYDESIHFQDNLTVMLFVGVNGVGKTTS
                     IGKLAHRYKRAGKKVMLVAADTFRAGAVAQLAEWGRRVDVPVVTGPEKADPASVVFDG
                     MERAVAEGIDILMIDTAGRLQNKDNLMTELEKIGRIIKRVVPEAPHETFLALDASTGQ
                     NALVQAKEFSKITPLTGIVLTKIDGTARGGVVLAIREELNIPVKLIGFGEKIDDIGEF
                     NSENFMKGLLEGLI"
     gene            complement(54387..55874)
                     /locus_tag="VQ543_000332"
     CDS             complement(54387..55874)
                     /locus_tag="VQ543_000332"
                     /EC_number="1.1.1.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000096131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate dehydrogenase"
                     /protein_id="HET2611123.1"
                     /translation="MSSKVIVTIFGASGDLAKRKLYPSLFRLYQSGNLSKHFAVIGTA
                     RRPWSKEYFESVVVESILDLADSTEQAQEFASHFYYQSHDVNDSEHYIALRQLQAELN
                     EKYQAEHNKLFFLSMAPQFFGTIAKHLKSENIVDGKGFERLIVEKPFGTDYATASKLN
                     DELLATFDEEQIFRIDHYLGKEMIQSIFAVRFANLIFENVWNKDFIDNVQITFAERLG
                     VEERGGYYDQSGALRDMVQNHTLQLLSLLAMDKPAIFTKDEIRAEKIKVFKNLYHPTD
                     EELKEHFIRGQYRSGKIDGMKYISYRSEPNVNPESTTETFTSGAFFVDSDRFRSVPFF
                     FRTGKRLTEKGTHVNIVFKQMDSIFGEPLAPNILTIYIQPTEGFSLSLNGKQVGEEFN
                     LAPNSLDYRTDATATGASPEPYEKLIYDVLNNNSTNFSHWDEVGASWKLIDRIEELWA
                     ENGAPLHDYKAGSMGPQASFDLLEKFGAKWTWQPDIAYRQDGRFE"
     gene            complement(56023..56763)
                     /locus_tag="VQ543_000333"
     CDS             complement(56023..56763)
                     /locus_tag="VQ543_000333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HET2611124.1"
                     /translation="MAKLKIDVNDLHKHYGKNEVLKGITTKFYEGDVVCIIGPSGSGK
                     STFLRSLNLLEEVTSGHITVNGYDLTEKTTNVDHVRENIGMVFQHFNLFPHMSVLDNI
                     TFAPIEHKLMTKEEAEELGMELLEKVGLADKANANPDNLSGGQKQRVAIARGLAMNPD
                     IMLFDEPTSALDPEMVGDVLNVMKELAEQGMTMIIVTHEMGFARQVANRVIFTADGEF
                     LEDGTPDQIFDNPQHPRLKEFLDKVLNV"
     gene            complement(56763..58928)
                     /locus_tag="VQ543_000334"
     CDS             complement(56763..58928)
                     /locus_tag="VQ543_000334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HET2611125.1"
                     /translation="MKKKFLAFLLILFPIFSLGIAKAETIKIVSDTAYAPFEFKDSDQ
                     TYKGIDVDIINKVAEIKGWNIQMSYPGFDAAVNAVQAGQADAIMAGMTKTKEREKVFT
                     MSDTYYDTKVVIATTKSHKISKYDQLTGKTVGVKNGTAAQRFLETIKDKYGFTIKTFD
                     TGDLMNNSLSAGAIDAMMDDKPVIEYAINQGQDLHIEMDGEAVGSFAFGVKKGSKYEH
                     LVTEFNQALAEMKKDGSLDKIIKKWTASSSSAVPTTTTLAGLKAIPVKAKYIIASDSS
                     FAPFVFQNSSNQYTGIDMELIKAIAKDQGFEIEITNPGFDAAISAVQAGQADGIIAGM
                     SVTDARKATFDFSESYYTANTILGVKESSNIASYEDLKGKTVGVKNGTASQTFLTENQ
                     SKYGYKIKTFADGSSMYDSLNTGAIDAVMDDEPVLKYSISQGQKLKTPISGTPIGETA
                     FAVKKGANPELIEMFNNGLANLKANGEFQKILDKYLASESSTASTSTVDETTLWGLLQ
                     NNYKQLLSGLGITLALALISFAIAIVIGIIFGMFSVSPYKSLRVISEIFVDVIRGIPL
                     MILAAFIFWGIPNFIESITGQQSPINDFVAGTIALSLNAAAYIAEIVRGGIQAVPVGQ
                     MEASRSLGISYGKTMRKIILPQATKLMLPNFVNQFVIALKDTTIVSAIGLVELFQTGK
                     IIIARNYQSFKMYAILAIFYLVIITLLTRLAKRLEKRIR"
     gene            59101..60054
                     /locus_tag="VQ543_000335"
     CDS             59101..60054
                     /locus_tag="VQ543_000335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000792120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET2611126.1"
                     /translation="MKNKRIFKDFQASKMNLNLYTSPLLAFVFVFIGEFVAYTLYGIS
                     LLALIGLARNFGEAGQNLASYLQTLHQSLTDKTSDFRLILGLLAFGFILNTVFRWTRK
                     VEKRPIRTLGFYRENCLSNLLKGFSLGLALFLLTLLSLVVLGQYRLESIHLNPYYLAF
                     VVFTIPFWILQGTAEEVVARAWLLPQLASRTNLKLAILISSLFFTLLHMGNSGLTPLS
                     LVNLFLFGVAMALYLLKTDTVWGVAGIHGAWNFAQGNLFGILVSGQPSGTSLMTFLPQ
                     GNQDWLSGGSFGIEGSIMTSLVLLLLIVYLANKLKKENERM"
     gene            60131..62119
                     /gene="uvrB"
                     /locus_tag="VQ543_000336"
     CDS             60131..62119
                     /gene="uvrB"
                     /locus_tag="VQ543_000336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit B"
                     /protein_id="HET2611127.1"
                     /translation="MINHITDNQFKLVSKYQPSGDQPQAIEQLVDNIEGGEKAQILMG
                     ATGTGKTYTMSQVISKVNKPTLVIAHNKTLAGQLYGEFKEFFPENAVEYFVSYYDYYQ
                     PEAYVPSSDTYIEKDSSVNDEIDKLRHSATSALLERNDVIVVASVSCIYGLGSPKEYA
                     DSVVSLRPGLEISRDKLLNDLVDIQFERNDIDFQRGRFRVRGDVVEIFPASRDEHAFR
                     VEFFGDEIDRIREVEALTGQVLGEVDHLAIFPATHFVTNDDHMEVAIAKIQAELEEQL
                     AVFEKEGKLLEAQRLKQRTEYDIEMLREMGYTNGVENYSRHMDGRSEGEPPYTLLDFF
                     PDDFLIMIDESHMTIGQIKGMYNGDRSRKEMLVNYGFRLPSALDNRPLRREEFESHVH
                     QIVYVSATPGDYENEQTETVIEQIIRPTGLLDPEVEVRPTMGQIDDLLGEINARVEKN
                     ERTFITTLTKKMAEDLTDYFKEMGIKVKYMHSDIKTLERTEIIRDLRLGVFDVLVGIN
                     LLREGIDVPEVSLVAILDADKEGFLRNERGLIQTIGRAARNSEGHVIMYADTVTQSMQ
                     RAIDETARRRKIQMAYNEEHGIVPQTIKKEIRDLIAVTKAVAKEEDKEVDINSLNKQE
                     RKELVKKLEKQMQEAVEVLDFELAAQIRDMMLEVKALD"
     gene            62129..62692
                     /locus_tag="VQ543_000337"
     CDS             62129..62692
                     /locus_tag="VQ543_000337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET2611128.1"
                     /translation="MIYLRKLKREDLMSLWEMAYSQLNPVWKQYDAPYYDDYQYFSNF
                     KEFELQKSESILSNSNRLGIFVDDKLVGTVSRYWVCKQTRWMELGIGIYDKKFWNTGI
                     GKVAMLQWIDRTFQDYLELEHLGLTTWSGNLGMMKLAEKLRMKKEAHIPKVRYYQGKY
                     FDSIKYGILREDWEKTNDGYYQINGNS"
     gene            62658..63146
                     /locus_tag="VQ543_000338"
     CDS             62658..63146
                     /locus_tag="VQ543_000338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET2611129.1"
                     /translation="MTVIIKSMETPEEIEGKPLVHWQTWREAYDGLLPAEFQETMTLE
                     RCRFFSQKYPENTLIAMDGMKVVGFISYGNFRDETIQAGEIIALYVLKDYYGKGIAQK
                     LIKAALIALNHFSEIFLWVLKDNKRAIAFYQKMGFTFDEQEKILELGKPIKEKRMVFY
                     SK"
     gene            63219..63686
                     /locus_tag="VQ543_000339"
     CDS             63219..63686
                     /locus_tag="VQ543_000339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000085289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HET2611130.1"
                     /translation="MSRAQLTILTNICLIEDLEAQRVVMQYRAPETNRWSGYAFPGGH
                     VENGESFAESVIREIYEETGLTIQNPQLVGIKNWPLDTGGRYIVVCYKATEFSGTLRS
                     SDEGEVSWVQKDQIPNLDLAYDMLPLMEMMEASDKSEFFYPRRTEDDWEKKIF"
     gene            complement(63683..64198)
                     /locus_tag="VQ543_000340"
     CDS             complement(63683..64198)
                     /locus_tag="VQ543_000340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription repressor NadR"
                     /protein_id="HET2611131.1"
                     /translation="MTKDRKQALLQLLKEAPKALNGQSLAEHFHVTRQVIVQDIAILR
                     ADGAPILSTNRGYIYKQIDTNPYVHKLFKVKHEVEEIGQELLAIVDNGGHVQNTLIDH
                     PVYGEIETLLKLSCRRDVQHFLEQVEHSDFKPLSELTDGVHYHLVEAETQQDLHYIEE
                     ALDQLGYLVKD"
     gene            complement(64210..64737)
                     /locus_tag="VQ543_000341"
     CDS             complement(64210..64737)
                     /locus_tag="VQ543_000341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HET2611132.1"
                     /translation="MNTRKKTQFMTMTALLTAIAILIPIVMPFKIVIPPASYTLGSHI
                     AIFIAMFLSPLMAVFVILASSFGFLMAGYPMVIVFRAFSHISFGALGSLYLQKFPDTL
                     DKPKSSWVFNFVLAVVHALAEVLACVLFYATSGTNVENMFYVLFVLVGFGTIIHSMVD
                     YTLALAVYKVLRKRR"
     gene            complement(65015..65578)
                     /locus_tag="VQ543_000342"
     CDS             complement(65015..65578)
                     /locus_tag="VQ543_000342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HET2611133.1"
                     /translation="MKKRSNIAPIAIFFATMLVIHFLSSLIFNLFPFPIKPTIVHIPV
                     IIASIIYGPRVGVTLGFLMGLLSLTVNTITILPTSYLFSPFVPNGNIYSAIIAIVPRI
                     LIGLTPYLVYKLMKNKTGLILAGALGSLTNTIFVLGGIFFLFGNVYNGNIQLLLATVI
                     STNSIAELVISAILTLAIVPRLQTLKK"
     gene            complement(65562..66113)
                     /gene="coaC"
                     /locus_tag="VQ543_000343"
     CDS             complement(65562..66113)
                     /gene="coaC"
                     /locus_tag="VQ543_000343"
                     /EC_number="4.1.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenoylcysteine decarboxylase"
                     /protein_id="HET2611134.1"
                     /translation="MANILLAVTGSIASYKSADLVSSLKKQGHQVTVLMTQAATEFIQ
                     PLTLQVLSQNPVHLDVMKEPYPDQVNHIELGKKADLFIVVPATANTIAKLAHGFADNM
                     VTSTALALPSHIPKLIAPAMNTKMYDHPVTQNNLKTLETYGYQLIAPKESLLACGDHG
                     RGALADLTIILERIKETIDEKTL"
     gene            complement(66125..66814)
                     /gene="coaB"
                     /locus_tag="VQ543_000344"
     CDS             complement(66125..66814)
                     /gene="coaB"
                     /locus_tag="VQ543_000344"
                     /EC_number="6.3.2.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000699493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenate--cysteine ligase"
                     /protein_id="HET2611135.1"
                     /translation="MKILVTSGGTSEAIDSVRSITNHSTGHLGKIITETLLSAGHEVC
                     LITTKRALKPEPHPNLSIREITNTKDLLIEMQERVQDYQVLIHSMAVSDYTPVYMTGL
                     EEVQASSNLKEFLSKQNHQAKISSTDEVQVLFLKKTPKIISLVKEWNPTIHLIGFKLL
                     VDVTEDHLVDIARKSLIKNQADLIIANDLTQISADQHRAIFVEKNQLQTVQTKEEIAE
                     LLLEKIQAYHS"
     gene            67044..68714
                     /locus_tag="VQ543_000345"
     CDS             67044..68714
                     /locus_tag="VQ543_000345"
                     /EC_number="6.3.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019803354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate--tetrahydrofolate ligase"
                     /protein_id="HET2611136.1"
                     /translation="MKTDIEIAQSIELKPIVDVVEKLGISYDDLELYGKYKAKLSFDK
                     IRAVESNPVGKLILVTAINPTPAGEGKSTLTIGLADALNKIGKKTMIAIREPSLGPVM
                     GIKGGAAGGGYAQVLPMEDINLHFTGDMHAITTANNALSALIDNHLHQGNELEIDQRR
                     ILWKRVVDLNDRALRHVTVGLGGPLNGIPREDGFDITVASEIMAILCLATDIEDLKRR
                     LANIVIGYRYDRTPVSVGDLQVEGALALILKDAIKPNLVQTIYGTPAFVHGGPFANIA
                     HGCNSVLATTTALHLADYTVTEAGFGADLGAEKFLDIKTPNLPTSPDAVVIVATLRAL
                     KMNGGVAKDALTEENVEAVRAGFANLKRHVENIRKFGIPAVVAINEFVSDTEAEIAVL
                     KELCASIDVPVELASVWADGAEGGVALAETVVKTIAENPANYKRLYDNALSVQEKIEK
                     IVTEIYRGSKVNFEKKAQTQIAQIVQNGWDKLPICMAKTQYSFSDNPNALGAPENFEI
                     TIRELVPKLGAGFIVALTGDVMTMPGLPKRPAALNMDVESDGTVLGLF"
BASE COUNT        20956 a        12351 c        15056 g        20503 t
ORIGIN      
        1 acaatgctat atggcataaa tcaagtgcct taaagattcc gactaatatt ggctttgcat
       61 ttattcctcc atacacacca gagatgaacc cattgaacaa gtgtggaaag agattcgtaa
      121 acgtggattt aagaataaag ccttttaaac tttggaagat gtcatgaatc aactccaaga
      181 tgttatacaa ggactggaga aggaggtgat aaagtccatc gttaatcgga gatggactag
      241 aatgcttttt gaaagcagat gagtataagt cctcgttttg aagccttgga acaggccatt
      301 gcctccaaag atttggaaaa agtccgagaa gcttttaaga aaatgaattc cacttggacc
      361 atcaatgaaa gtgtggttcg tgacaatagt acagctcatt atggacgtgt tgaaacagct
      421 atttccttcc tgcctagtag catggaaacc gaacctacag atgagtctgg aacatgaaaa
      481 cagcagttga tttcaagaaa caaaaaagaa cagtcgaaac tgttctttta tcattatttg
      541 agaccgtatt ttttgttgaa acgatccacg cgtccatctg cttgagtgaa cttttgacgt
      601 ccagtgtaga atgggtgtga gtctgatgaa atttccacac ggatcaatgg gtaagtttcg
      661 ccttcgaact caactgtttc gttagagcgt tttgttgaac cgctaaggaa ttggtaacca
      721 gtagttgtgt ccatgaagac aactgggcga tattctggat ggatatcttt tttcattttg
      781 caatatttcc tttctgccat ggtctctttg cgagccatag attgttacca tactagtcta
      841 tcagattctg aaaagtttgg caagtatttt atcagttttt aagcaagttt tttaactttt
      901 ggtagatgat ttcattttct tctaggctat aggaattagc accacttgct agagggtggc
      961 ctccaccatc atgctccttg gcgatttcat tgataggatg gattttactg cgtaagcgaa
     1021 cgcggtagtg gccatcagcc tgttccacaa aaattcccca gagactaaca ctatcaatac
     1081 gcccaggtgc acctacaatg gccgcagttt cagcatcggt tacattgtat tgtttcaaga
     1141 ttttctgact caggataacg cgagcagcac cattttcatc cacttccaga tggtcgtaga
     1201 tgtagccttg cagtttagca attttgtagc tcatagtgtc cattttgcga gtgagagccg
     1261 caaagtcaaa gttatgttct ctcaaataag cagccaggcg aagagtccgt gcagtggtag
     1321 aagggtagag gaagcgacct gtatcaccga caattcctgc aaagagcaac tcagcatcgc
     1381 gatctgccaa ggctagttgg gttgtttggg caaatagggt aatcatctcg ctagcgctac
     1441 ttgaactagt atcgacccaa gacaggtcac cgtatacatc atcatttgga tggtggtcaa
     1501 tcttaatgag aaaatcacct tgactatagc gcttatcatc gatacgagca gtattagctg
     1561 tatcacagac gatgacaagt gcgccttggt aggctctatc ttcaacaaga tccatctcag
     1621 ccatccaagt aagagttggt tcatcaaaac cgacggcttt gatggttttt tctgggaaat
     1681 gatgttccag caaggctttc aatcccacct gacttcccaa ggcatcaggg tctggtttca
     1741 tatgacgatg aatgataatg gtgttgtatt ctttaatttt ttctaaaatt tgttggcaaa
     1801 tctccataaa taacctcaat tctttctcat ttcattgtag cacaagaatt tttattttta
     1861 aaatgaaaaa gatgtgatat aatggagaaa gataaattga ggaggacgat atggcattag
     1921 caaaaattgt atttgccagt atgaccggta ataccgaaga aattgcagat attgtagcag
     1981 acaaattacg tgacttgggc ttggatgttg atgttgatga atgtacaact gttgacgctt
     2041 cagacttctt ggaagcagac atcgctatcg ttgcgaccta tacttatggt gatggtgaat
     2101 tgccagatga gatgatggac ttctacgaag acctagcaga tctcaacttg aatggcaaaa
     2161 tctacggagt ggtcggctca ggagatacct tctacgatga attctgtaag gctgttgatg
     2221 actttgaccg tgtctttgtg tcaacaggag cagaaaaagg ttcagagtgt gttaaagttg
     2281 atctttctgc cgaggaagaa gatattgaac gcttggaaca attcgcagaa gaattggctg
     2341 ctaaagtagg ataagcataa aagtgcgctg atgtaatcaa tcagtgcatt tttcttatcg
     2401 agagttggga ttttactagc ctaattgatg gctttttgat acaataattc aaataaagga
     2461 ggagactgta tggatttaga tattattcgt caagaaatcg atcaaatcga cgaccaaatt
     2521 gtcaaactgt tagaagaacg aatgcattta gttgaggggg tggttgctta taagaaagct
     2581 tcaggtaaac cgattttaga tactaagaga gaagaagtta tttttgaaaa ggttaggagt
     2641 cgtgtagagg acaagcgcta tcaggagact attgtcgcga ctttttcgta catactcaaa
     2701 cgttcgcgtg attatcagga tcaaaatatc aaatgaaaaa agaacaattt tatccgctag
     2761 gaatttttct agctgctatg ttgggcggac ttgtccgata tctagtttcc acctggttac
     2821 cagccagtcc agactttcct tggggcactc tctttgtcaa ctatctggga attttctgct
     2881 tgatttttct tgtcaagggc tatctggtct ataaggggac tagtaagggc ttgattttag
     2941 cactggggac gggtttttgc ggaggtttaa caactttttc cagcctaatg cttgatactg
     3001 tgaagctgct tgatacaggg cgttatttta gtttagtcct gtatttgctt ttgagtatcg
     3061 gtggaggcct gcttttagct tactatttgg ggaggaagaa atggtaatcg tctatcttgc
     3121 aatcgcctgt ggcttgggag cactcgtacg gtatttcttt tctcgctata atcaagcttc
     3181 taaattgcca ctcggaacgc tcatagctaa tcttttaggt tgttttttaa ttggagtatt
     3241 ctacaatcat gtagagtcta aggaagtata tgctattcta gcaacaggat tttgtggcgg
     3301 tttaacaact ttttcgacct tgaatgacga acttcaaaga ctgctaagtg ataagaaggt
     3361 cttttattct tacctgactt tgacttacat aggtggtttg gttgcgattt ttttaggaat
     3421 tttgctataa atttctttac ttttttttag aaatttggta aactatatct tgtgtgtaat
     3481 ggacgcacaa aaatacagtt tatccgctga ggaagattcc tcaagattga caaagatagg
     3541 agaataaaat gaatccatta atccaaagct tgactgaagg tcaacttcgt acagatatcc
     3601 catcattccg tcctggtgac actgttcgtg tacatgcgaa agttgtcgaa ggtaaccgtg
     3661 aacgtatcca gatttttgaa ggtgttgtta ttgcacgtaa aggtgctggc atctctgaaa
     3721 actacacagt tcgtaaaatc tctaacggtg taggtgttga gcgtatcttc ccaatccaca
     3781 ctccacgtgt tgaaaaaatc gaagttgtac gttacggtaa agtacgtcgt gcgaaattgt
     3841 actacttgcg tgctcttcaa ggtaaggcag ctcgtatcaa agaaatccgt cgttaattcg
     3901 actaaaaaac tctgcttttt cagcagagtt tttatctagc tcccttagtt caatggatat
     3961 aacaactccc tcctaaggag tagttgcagg ttcgattcct gcagggggca tgtaattaga
     4021 tatcaaagaa gtttgtcaaa gagtctttga tattaaaaga acgcataata taggggattg
     4081 tctccataat attatgcgtt ttattattga aaaatttggg caatcatcag ataaaattga
     4141 gactatatcg agtatataaa tgtttgtata gtcaatttat tcaaaatcgt caagttctaa
     4201 attatttaaa ggactataac attcatattt ctttaagtaa ttgtttattt cttcagcagt
     4261 ggaacgaggt aaattaactc ttaaatagtc aatatcttcc ttagataaaa aatgatttgc
     4321 attcaaaatt gagaagcgaa ataatgcttc atcaaaagca aaatcataat cgtcatcaga
     4381 taatgattcc attaatgttt gaatatgttt tagtgagtag tcaggtatcg aatcgggata
     4441 atatactgga taatcagtgg ctgaaaaatt gttttctaat cctgaaatag taattatcaa
     4501 agattctatg taatatatta aagcatgttt aatattacct tcttgttcca aatgtcttcc
     4561 ctgagccttt cgtgtgttag ataagcatcc aaaatctcct gatacagtat tcctatgagc
     4621 ttgtttattt aagagactcc attttatatc accaaaagtt gctttaaaag agatattgtt
     4681 tttttcttta caataatctt ccatacttat gtctttatca tagtatgctt tgatatagtc
     4741 actatgttcg ataataagat tttgtgcttc ttttgttagt ttaaattcga acggaatatc
     4801 taaattgtca atgttaacat tattaattat tcttgtaatt aattctgctt tttttccaga
     4861 agtagctaaa ttatgtttag ataatatagt ttttaattct actactgtaa gatatgataa
     4921 agtcttattt ttagtgaagt atcctaattt gtataattga ttgtgtgtag attcagggtc
     4981 aatttgaaga gagtatttaa aatatcttgg gaaattataa tttctccctg ttttttgagt
     5041 ccaatctatg agtatgagtt gcccaggagt aaggccacat tctaattcgt ttaggtaaaa
     5101 attgttacaa tcagaatttg tgtctctatt atgattattt tgttttaaat taaatagttt
     5161 gctaaaaaaa ttcattggat tttattgcta atcaattctt attgaaaaat gatactttta
     5221 cagtacccat gttcggatgg catgggcaac gccggattcg tcatttgttt tggtgatgta
     5281 tttggcgatt tttttgattt ctggatttcc attttccatg acaacggggt ttccaacgac
     5341 ttccagcatg ggacggtcat tttcttcatc accgattgcc atggtttcat ctttggtcaa
     5401 tccgagtttt tcagccaagt gagtaatggc tgaacccttg tctacattct ttttaaggag
     5461 ttcgaggtag aaaggagcag atttgttgat ggagtagcgc tcgtaaaatt ctgctggaat
     5521 tttttcaatc gcagcatcga gaatttctgg ttcatcgata aacatacatt taacaatttc
     5581 tttgccagcc atttcttcag gggtacggta gaagataggc atgctgacga gggttgattc
     5641 gtgtacagtg tattttccga tattgcgatt tgcagtatag ataccgtcct tggtaatggc
     5701 atgcatgtgg acaccgagct tgcgactgag gaattccata tccagataat cctcataggt
     5761 caaggattcg ctgataatct catggccagt agcagtttct tggacaaggg caccattgaa
     5821 ggtcaccaca tagtcacctt ggtctctcaa ctgcaagtcg tccagaagtt tggcaacacc
     5881 tgcgatgggg cggccagttg caatcacgac tttgacacca gcttctttgg catcttggat
     5941 ggcagaaaag acttcaggag tgatttcctt ttggctgttg actagggttc cgtcaatatc
     6001 gacggcaatt agtttaatac tcataaaatt cctcttctag tttttatttg gggtaaaatg
     6061 atcgttctca atcaagtgta aaaattgctg ggtaatgctt gcgaagatgc tgttttggtc
     6121 taacatttct ttagggaaat agaaacgatt atctccgtgg cgactgccag caagggattg
     6181 gacgatagga gacaggctag agagttcggc cagttctcca tttttttgta aaatctcaat
     6241 ctgtgtccgt ggattttgag attcgggacg atagatatca taagggaggt caaagttctt
     6301 atgaatggca gtatagtagt cgggatcaaa gccgatgtcc tcaaccaatt ttctcatgct
     6361 agtaagttga tcttggtcct cttgtgaaaa ggtaatggat ttaaagacct tgcggttgac
     6421 aaagcgttga gataaatctg caagaatttt gtcaggacta gtcatccaaa gctggaagta
     6481 ggtattcatc acgccatcat ccagagccag atagtcagtc aaggtcacat ttttttcgaa
     6541 gaaaggcagg agatgtgggg aagttcgtgc aaagaaattc ttgtcctcag ggtagagttc
     6601 cttggcgcgc ttgagaagat tctgtaggag aacttccatg gcgcgtgttg ctgggtggaa
     6661 ataaacctgc atgtacatct ggtagcgact gaggacgtag tcttcgatgg cgtgcatgcc
     6721 attgcgctga aaggcgatac cattttcgac aggacgaatg actcggagga tgcgagtcag
     6781 gtcaaattcc ccataggatg ctcctgtaaa ataggagtcg cgcaagagat agtccatgcg
     6841 atctgcgtca atctgactag aaatgagctg cacgacctgc ttattaggat aggtatggtc
     6901 aatgacactg gccacctttt ctgggaaatc aggtgccact tgtagcagga cttggtgaat
     6961 ctctgtctca ggattttgaa taatctcctg agtaatggct tcatggtctg tatcaaagag
     7021 attttcaaaa gtatgggagt aggcaccatg cccaaggtcg tgtaggagag cagcggtcac
     7081 ggtcaagaga gactcggcag gattccattc ctcaggatat ttttcttcga aaatctctgt
     7141 gatgcgtcgt gcaatttcat agactcctag acagtgagag aagcgactgt gttctccacc
     7201 gtggaaggta taactggaag ttcccagttg tttgatccgg cgcaaacgct gaaattcttt
     7261 tgtattaatc aagtcataga tgatttgatt attgacatgg atgtagttgt gaactgggtc
     7321 acggaatact ttttcgttca tatgaccatt atagcaaaat cctgctcttt ttggtaaaat
     7381 agtaggacaa gagacaagaa agagggcctg atgtgaagat tcggatgcga aatacaattc
     7441 agtttgatga gcagttggaa gtgattgacc agctttatga tgtggaagtg catgaaaaag
     7501 gagattatag ctacctgctt ttctataatg aggaaaagga aaaagtagtg attaaatttc
     7561 atggtcaaga acttatgatg agccgatttt ctaatcccaa gaccattatg cgctttctaa
     7621 aggatagcga tagtttagcc tatattccta cacctatggg catgcaggag tttatcatcc
     7681 aaacgagcca ttatcaagtt gataggcaaa agattgaact agattatcaa ctacaaaatc
     7741 aagagggaca tccttttgcc agctatcaat tggaaattac ttggggctag gctcatgtct
     7801 ttttcaaatt tagctatcta tcttcttgga tcggcttcct agtgtggtag attaggctaa
     7861 tttttggtat aataaaagtt atggaaatcg aaaaaaccaa tcgtatgaat gcgctctttg
     7921 aattttatgc ggcgcttttg acagataagc aaatgaatta tatcgagctc tactacgctg
     7981 atgattacag ccttgctgaa attgccgagg agtttggtgt cagtcgtcag gctgtctatg
     8041 acaatatcaa gcgaacagaa aagattctgg aagattatga gatgaaattg cacatgtact
     8101 cggactatat tgtccgcagt cagatttttg atcagatttt ggagcgctat cccaaggatg
     8161 actttctgca ggagcagata gaaattttaa caagcattga taatagagaa taagaggaag
     8221 aaaaatggca tttgaaagtt taacagaacg tttgcagaac gtctttaaaa atctacgtaa
     8281 aaaaggaaaa atctctgaat ctgatgtcca agaggcaacc aaagaaattc gcttggcctt
     8341 gctcgaggcc gacgttgcct tgcctgttgt aaaggacttt atcaagaaag ttcgtgagcg
     8401 tgcagtcggg catgaggtca ttgatacact taatcctgcg caacagatta ttaaaatcgt
     8461 tgatgaggaa ctgacagccg ttttaggttc tgatacggca gaaattatca agtcacctaa
     8521 gattccaacc atcatcatga tggttggttt acaaggggct ggtaaaacaa cctttgctgg
     8581 taaattggcc aacaaactca agaaagaaga aaatgctcgt cctttgatga ttgcggcgga
     8641 tatttatcgt ccagctgcca ttgaccagct taagaccttg ggacaacaga ttgatgtgcc
     8701 tgtctttgca cttggaacag aagtaccagc tgttgagatt gtacgtcaag gtttggagca
     8761 agcccaaact aatcataacg actatgtctt gattgatact gcgggtcgtt tgcagattga
     8821 tgagctcctc atgaatgagc ttcgtgatgt gaaagcattg gctcaaccaa atgaaatctt
     8881 gcttgtcgtt gatgctatga ttggtcagga agcagccaat gttgcgcgtg agtttaatgc
     8941 tcagttggaa gtgactgggg tcatccttac caagattgat ggcgatactc gtggtggtgc
     9001 tgctctgtct gttcgtcaca ttactggaaa accaatcaag ttcactggta caggtgaaaa
     9061 gattacggac attgaaacct tccacccaga ccgcatgtct agccgtatcc ttggtatggg
     9121 ggatatgctc actttgattg agaaagcttc tcaggaatac gatgaacaaa aagcccttga
     9181 aatggctgag aagatgcgcg aaaacacctt tgattttaat gatttcatcg atcaattaga
     9241 tcaggtgcaa aatatggggc cgatggaaga cttgctcaag atgattccag gtatggccaa
     9301 caatccagcc cttcaaaaca tgaaggtgga tgaacgccag attgctcgta aacgtgccat
     9361 tgtgtcttcg atgacacctg aagagcgtga aaacccagat ttgttaaatc caagccgtcg
     9421 ccgtcgtatt gctgctggtt ctggaaatac attcgtcgaa gtcaataaat tcatcaagga
     9481 ctttaaccag gctaaacagc tcatgcaggg tgttatgtct ggggatatga ataaaatgat
     9541 gaagcaaatg gggattaatc caaataacct tcctaaaaat atgccaaata tgggaggaat
     9601 ggatatgtct gcccttgaag gaatgatggg acaaggcggt atgcctgact tatcagctct
     9661 cggaggagca ggaatgccag atatgagcca gatgtttggt ggcggtttga aaggtaaaat
     9721 tggtgaattt gccatgaaac agtccatgaa acgtatggct aacaaaatga agaaagcgaa
     9781 gaagaaacgc aagtaagaca agagattgat gcaaatctca tttgatgaga aaataaagta
     9841 aaaatttcta tgataaaacg tacagtatca aggttttaga atatctgata ttatacgttt
     9901 tttgatttta ataattttgt taagacactt ttattatggt atacgaaaaa tccactcagc
     9961 tgtctgagtg gattaggtgt atttagactc ttagtcttta ttttcgtatg gcaagatcaa
    10021 gttcaagatg attcctgtca tggctgaaag ggcagtacct gaaagtgtaa ctggaccaag
    10081 tttaaggata gctcctccaa gtccaagaac caacatagca cttgcgatga tgaggtttcg
    10141 catttgagcg aaatcaacac gttctttaat caagactttc aaaccattgc tggcgataac
    10201 cccatagaga aggattgaca taccaccaag tacagcgttt ggaatagttg aaatcaaggc
    10261 agtgaattta ccaaggaagc tgagggcaat cgcgatgaag gcagcgttac ggataactga
    10321 gacagaagcg atacgagtca taccgataac ccctgtattt tctccgtaag ttgtattggc
    10381 tggtccacca aggaaggcag aaacagaagt tgcgataccg tcaccaagaa gagtacggtg
    10441 aagacctggt tcttttaaga attgacgacc acagatttga cccaaaacag tatggtctcc
    10501 gatatgttca gaaattgtta cgatagcgat tggcaagata gcgatggctt ctggaccaaa
    10561 gtaaagattg tactctttaa aggcaccacc tgtgctaaat ggcaagtaga aaccaggaat
    10621 ttcgaaccag ttggctttaa gaactggtgt aaagtcaacc aagccaagag ttagtgcgaa
    10681 aaggtaacca ccgataatgg caaagaggaa tggaatgatt cgtaggaagc cttttccttt
    10741 tgtattgata aaggcagcaa ttaggaaagt aacaacggct accagagcat ttttccaatt
    10801 tccgtctgct acaagacctg cattggtaac agctgaacct gcaagtccaa gaccgataac
    10861 gatgatcata ggaccgataa tgattggtgg caagagttta tcaatccatt ttgttcctac
    10921 aaatcggatg ctggtagcaa caaggacata gaccaaacca gtcaagataa cccctgtttg
    10981 ggcagcagat acatcccccc ccatttcttt catagccagt gacatagctg tgataaaggc
    11041 aaatgaagaa cctagataaa ctggaacttt aaaaccagta gcaatcatgt agatgagtgt
    11101 tccaacacct gaagcaaaaa gggcaacaga tacaggcatt cccaaaatca atggtaccaa
    11161 gatggtcgca ccaaacatgg cgaaaacgtg ttggaaacta aggagaattc cttttccagc
    11221 cgaaggacgt tggtcaacgt ctagtaacaa atcaacagtt gattcttgtt tcatataaac
    11281 ctcacttttg ggcatcaaaa aagagcccat tattttacag caataggccc tcagagtaag
    11341 acttctttaa aatttagatt ttaaagagtt ttaaatattt ctgcgtcttc gtcacctcac
    11401 gggatgacat taaaaacctt tgcttaggat agtatagcag aaaaaaatga ttttgtaaat
    11461 cattttttcc cgagcctaga aataaaagag cgaggctgat tttgtaaatc attttttccc
    11521 gagcctagaa ataaaagagc gaggctgatt ttgtaaacat ttgtttacta aaaaatttaa
    11581 agtgggcgtt tatttggcat accagcctta cgcggatatt tatttggtgt ttcttttttc
    11641 ttttctacca ctgtgatata gcgcggatct ctattcggta gggcgtagct gagattgtct
    11701 tcgaccttac taaaaaggag attgagggca ttcttagctt ctaataattc ctcaggcgca
    11761 ttgctggcct tgagtgccaa tagttttcca ccaaccttaa ggtagggaat ggtcaattca
    11821 gataggacct gcatacgggc aaccgcacga gctgttacaa aatcatattg agcacggaag
    11881 ttcttgtctt gggcaaaatc ttcggcacgt ccgtggtaga aatgaactcc gttcaaatcc
    11941 agttcttgag ccaagagttg taggaagttg atgcgcttat tgagtgaatc aataatggtc
    12001 acatctaact ccggatagag aattttcatt ggtagactag gaaatcctgc cccagccccg
    12061 atatcaagaa gtttgatagt ttcattggga atcaaacctt gaagaatggg tgcaatcgaa
    12121 tcgtaaaaat gtttgagata aacttcttcc ttgtccgtaa tcgccgtcaa attaatcttc
    12181 tcattccact cgaccaagag ctcaaaataa cgttcaaatt gttctttttg ctggtccgaa
    12241 agtggaagat tctgctcggc aagcaagttg taaaatgttt ttggtttcat agttatttcc
    12301 ttctttagta tcatcttatt ttaccacaat catagaaaat ttgatatact ggtactaatc
    12361 taaaagcaga aaggacttat attatgactt ggattattct tggagttatc gctcttattg
    12421 ttatttttgt gattgttagc tataacggtt tggttaaaaa tcgtatgcaa accaaggagg
    12481 cttggagtca gattgatgtt cagttgaaac gtcgaaatga cctcttgcca aacttgattg
    12541 agactgtaaa aggttatgcc aaatatgaag gttctaccct tgaaaaggtg gcagaactac
    12601 gtaaccaagt ggcggcagcg acttcaccag cagaagctat gaaagccagt gatgccctca
    12661 ctcgtcaggt ttcaggtatt tttgcagttg cagaaagcta tccagatttg aaagctagtg
    12721 ctaactttgt taaattgcaa gaggagttga caaacacaga aaataaaatt tcttactctc
    12781 gtcaactcta taacagtgtt gtcagcaact acaatgtaaa attagaaact ttcccgagca
    12841 atattatcgc tggaatgttt ggatttaaag cggcagattt ccttcaaaca tctgaagagg
    12901 aaaagtcggt tcctaaagtt gattttagcg gtttaggtga ctaagatgtt gtttgatcaa
    12961 attgcaagca ataaacgaaa aacctggatt ttgttgctgg tatttttcct actcttagct
    13021 cttgttggtt atgcggttgg ttatctcttt ataagatctg gacttggtgg tttggttatc
    13081 gcactgatta tcggctttat ctacgctttg tctatgattt ttcaatcgac agagattgtc
    13141 atgtccatga atggagcgcg tgaggtggat gagcaaacgg caccagacct ctaccatgta
    13201 gtggaagata tggctctggt cgctcagatt cctatgcccc gtgttttcat cattgatgat
    13261 ccagccttaa atgcctttgc gacaggttct aatcctcaaa atgcggctgt tgctgcgact
    13321 tcaggtctac tagctatcat gaatcgtgaa gaactagaag ctgttatggg acatgaagtc
    13381 agtcatattc gtaattatga tatccgtatt tcgactattg cagttgccct tgctagtgct
    13441 atcaccatgc tttctagtat ggcaggtcgt atgatgtggt ggggtggagc aggtcgcaga
    13501 cgaagtgatg atgaccgaga tggaaatggt cttgaaatca ttatgctagt ggtttcccta
    13561 ctagctattg tactggcacc tctcgctgca accttggttc agctcgctat ttctcgtcag
    13621 agggaatttc tggcagatgc atctagtgtc gagctgactc gcaatcccca gggaatgatt
    13681 aatgccctag ataagttgga caatagcaaa cctatgagtc gccacgtcga tgatgctagc
    13741 agtgcccttt atatcaatga tcctaagaaa ggtggggggt tccaaaaact cttttatacc
    13801 cacccaccta tctcagaacg gattgaacgt ttaaaacaga tgtaaaagaa tccagaggtc
    13861 gtctctggat ttttgctatg ttgcaaattt ataaatcttc taaattaact agcttcaaac
    13921 cgtgttctgt catgcgatag atgatcgagc agacttcttt taagaaacga cggtcatgcg
    13981 aaacagtgat gagaccgcct ggataggttg caaagagttt tctgatttgg ggttgagaag
    14041 tgggagaaaa gtttcgtgtg ggttcatcca gcaggagaaa gtttggtttg cgcagaacta
    14101 gatccaaaag caggagtttt ccctgttgtc cgccagataa ggagcgaatt tgatgctgca
    14161 tttctggata actgaaattg agactggcta ggtgagattg gattttctga agttcctctt
    14221 tttccccagt tttgctgata taagctattg aggataaatc caattgcagt tttttgtggt
    14281 aatcttgtgg cataaaacca agtgaaatct ctcttttatc attcagaagt tgctgtaatt
    14341 tggctaacag agttgatttc ccaacaccat ttgggccgat gataccgatt ttttcttggc
    14401 cacggacagt tagttgcagt tcctgagcca aaacacggtc gtcaatggac aaattttctt
    14461 tttccagttg gactaagact ttagaagctg gtaatggttg gatgtctgaa aagaaaagtt
    14521 ggatttgttc ctcttcaagt ggcttttgag tcatggactg agctgtcttt tcgtagcgtt
    14581 tttcttgtga gaggacagtt ttcatctttt tagccaatag gcgaccggca gtactatctt
    14641 tggtagctcg aagcgcagtt tctacatttt gcttaactct ccgatgtttt tccatggttt
    14701 tatcgtaggc tctttggttg ttagcagctt gctgactttg tttggcaaaa ttagcctttc
    14761 tctgctcact atagctatca tagtctaaat gctctactag cgtttccgct tctttacggt
    14821 gtttgaccag tcgcaagtga acaatagtgt ctgccgtttc agaaagaaag tcttcatcat
    14881 gggaaatgaa aataacggtt tgcctggtct tttgaatctg gccttttagc caatcaactg
    14941 tctcaaggtc taggtcattt gaaggttcat ctaaaaatag aatctcaaag ggtttggcta
    15001 actcatggat aagctgaatt ttcaaagctt cgccccctga tagattgcca atctcttggt
    15061 cacttgcgaa acgattgcta tcaaaatgca attcctccgc caaacgatag aggatactgt
    15121 agtctaaatc aatagaatct aaaaagaagt agtcgtgtaa agttttcttt tttaggtcct
    15181 cagggacttt ttgaggaatg taggccagtg actgataatc agactggatg tctcccttga
    15241 tagtgaaatc agacaaatct tcccccatta aagttttaag taaggttgat ttaccatttc
    15301 cttcttcgcc aataatagct accttttccc cgtcttgtat ggtcatgctt aggtcagaga
    15361 caaggtctcg taaatctttg ttttgtgtga tggtcaggtg attgattttt atcatactat
    15421 tgccctttct agaatgtcga tagtgcataa caaaaagctc tactttacct agtagagccc
    15481 aaagtctatg tcaaaaaaac tctattaaca tgccagaaaa agagcataaa agagcacaca
    15541 aaaagagaca aaaacaagat ctactaaata aaggttcttt atttgataga cttagttgtt
    15601 catgtctccc ttacctccga gtattagtat ctttatacta tacttttaag gaaattttgt
    15661 caacagaaaa ctggaaattc tatgctctaa aatccaaaaa caggtccata gagacttagt
    15721 acgtgtttga catgctcgta atggatttta tcatagtttc gccaagcagt gcgtgcttga
    15781 tcgtttagtt ttaggctacc cagtccaatc agaggactgg tgggttggta aaatttctca
    15841 agatcaatta agatactgtt gttcaacttt tccgtttttt tgagctcttg catagtagtg
    15901 tttagcagct cttgtagtcg aatatcatct gccgtaccct gtttacagtt ttggtagctt
    15961 ttatttaact tggataggag ttgaatgagt ttcttgtctt ccatgtcttc catatgagca
    16021 tcctccttga tctgatgtac tctttcccta tagtatagca ctaaaaaata aaactgtcat
    16081 agtaaatatg ttaaaatttt gaattttaat tacaaagttt ggtgtgctga tttgtagcct
    16141 tttcatggta taatcaagag agtaaatctt tatggaggaa gtatgaaatt aaatattcaa
    16201 gaaattcgta agcagtctga aggtttgaac tttgaacaaa cgttagattt agttgatgac
    16261 ctgcgtgcac gtaatcaaga aattttagat gtaaaagata tccttgcagt tgggaaagta
    16321 caatatgaag accgtatgta tttcttagat tatcaactat cttataccat tgttcttgct
    16381 tcgagtcgca gtatggagcc agttgagtta gttgaatctt atccagtcac ggaagttttc
    16441 atggaaggcg caactaacca gctagatcaa gaagttttag atgatgactt ggtcttgccc
    16501 attgaaaatg gggagcttga ccttgctgag agtgtatcag acaatatcct gctaaacatt
    16561 cctatcaagg tcttgacggc tgaagaagaa gctggtcaag gatttatctc aggaaatgac
    16621 tggcaaatca tgacagagga agaataccaa gctcaacaag cagtaaagaa agaagaaaac
    16681 agtccttttg ctggcttaca aggactattt gacggagatg aataatggtc ttgtcaaaaa
    16741 aacgagcacg aaaggtgcta gaagaaatca ttgccctctt cccagatgcc aagcctagtc
    16801 ttgattttac caatcatttt gaactcctgg ttgcggtcat gttatcagcc cagacgacag
    16861 atgcagcggt aaataaggcc acaccaggtc tctttgttgc ctttccaaca ccccaagcta
    16921 tgtctgtagc gacagagagt gagattgctt cacatatttc tcgcttggga ttgtatcgga
    16981 ataaagctaa attccttaaa aaatgtgccc aacagttact agacgatttt gatggtcaag
    17041 tccctcagac acgtgaagaa ttggagagtt tggcaggtgt tggtcgcaag acagccaatg
    17101 ttgtcatgag tgtaggattt gggattccag cctttgcagt ggatactcat gtggagcgta
    17161 tttgcaaaca ccacgatatt gtcaaaaaat cagcgacgcc acttgaggtg gaaaagcggg
    17221 tcatggatat cttgccgcct gagcagtggt tagctgccca tcaggccatg atttattttg
    17281 gaagagccat ttgccatcca aaaaatccag agtgtgacca gtacccacaa ttatatgatt
    17341 ttagcaattt gtaagatgct acattgaaac tttttgcttg attttaagca tgctttgtgc
    17401 tatagtaaat gataactaaa tattccttta aacctgtccc gtgaggcagg caaggagcgc
    17461 gataaagtag aagggtgaag tctatactgt ttgcagtagg gctcgcttgg ctataaattt
    17521 caagtctcct tgtttaagga gacttttctt tttggaggtt tgtcatgaaa acaaaagaag
    17581 ttgtagacga attgaccgtc aaacgagcga ttacgcgtat tacttatgag attatcgaac
    17641 gcaacaaaga tttgaataag atcgtcttgg ctggtattaa aactcgtggt gtctttattg
    17701 cccaccgaat ccaagaacgt ttgaagcagt tagaaaatct ttcagttcct gttgtggaat
    17761 tggatactaa acctttccgt gatgatgtta aaagtggaga agatacttct ttggtttctg
    17821 tcgatgtgac agaccgcgaa gttatcttgg tggatgatgt gctctataca ggtcgtacca
    17881 tccgtgctgc tattgataat attgtcggtc atggtcgtcc tgcgcgtgtg agtttagcag
    17941 ttctagtcga tcgtggacat agagaattgc caatccgtcc agattacgtt ggaaaaaata
    18001 tcccaaccag tcgttctgaa gaaatcatcg tagagatgac agaacttgat gaccaagaca
    18061 gagttctgat tactgaagaa gcttagaaag ttaaaggagt agccatgtca gaaaatcaac
    18121 aagcattgaa ccatgtggtg tccatggaag acctcactgt cgatcaagta atgaaattga
    18181 tcaagcgagg aattgagttt aaaaatggag cccagcttcc ctatgaagac catccgattg
    18241 tttccaatct cttctttgag gattctacac ggacacataa gtcctttgaa gtcgcagaga
    18301 ttaaacttgg attggaacga cttgactttg atgtgaagac tagttcggtt aataagggtg
    18361 agacacttta tgacaccatt ttgactctgt ctgctttagg agtggatgtc tgtgtgattc
    18421 gccatccaga ggtcgactac tatagagaat tgattgctag tccaacgatt acgacttcca
    18481 tcatcaatgg tggagatggt tcgggccaac accctagcca gagcttgctt gatttgatga
    18541 ccatttatga ggaatttggc cactttgagg gtcttaaagt tgctattgca ggtgacttgg
    18601 accactcacg cgttgccaaa tccaatatgc agattttgaa acgcttggga gctgaactct
    18661 ttttcgctgg acctgaggaa tggagaagtc aagagtttgc agactatgga aagtttgtaa
    18721 ccattgatga aatcattgat caggttgatg tcatgatgtt tctccgtgtg caacacgaac
    18781 gccatgatag tggagctgta ttttcaaaag aagactatca tgcccaacat ggcttgactc
    18841 aagaacgtta cgatcgtttg aaagaaacag caatcctcat gcacccagct ccaatcaatc
    18901 gtgatgtaga aatagcagac cacttggttg aagcaccaaa atcacggatt gtccaacaaa
    18961 tgaccaatgg tgtctttgtt cgaatggcaa tcttagaatc cgtactagcg agtagaaacg
    19021 ccaactaaaa cacaagacgt taaaagacgc cagtgagcgt ccacgagagg tgaaaatatg
    19081 acaaaaagaa ttctagtatt agaagatggc acagtttttg aaggcaaggc cttcggagca
    19141 gatattgatg taacaggcga aatcgtcttt aatacaggga tgaccggcta ccaagaatcc
    19201 attacagacc agtcttataa tggacaaatc ttgaccttta cttatccttt ggtaggaaat
    19261 tatggtatta atcgtgatga ttatgaatcc attattccaa cttgtaaggg agtcgttgtt
    19321 tttgaagaag cgcgtagagc tagcaactgg cgcaaccaaa tgaccttgga tgaatttttg
    19381 aaagccaaga aaattccagg gatttcagga attgatacgc gtgctcttac caagattatc
    19441 cgtaagcatg gtactatgcg tgcaaccttg acccatgttg gggacagtat ggaccatgtg
    19501 acggaccagc tccaagcaac agttttaccg acagacaata tcaaacaggt ttctactaaa
    19561 acgtcttatc cagctccagg agttggtttg agcgtggtgc tagtggactt tggtctcaag
    19621 cactcaatcc tacgtgaact ttctaaacgc aactgtaacg tgacagttgt tccttattcg
    19681 acaacggctg aagaaattct ccatctcaat cctgatggag ttatgttgtc aaatggtcca
    19741 ggtaacccag aagacgttcc acaagcactc gacatgattc gcggtgtaca aggaaaaatt
    19801 ccaatctttg gtatttgtat gggacaccaa ctctttgcaa tggcaaacgg ggctaagacc
    19861 tataagatga agtttggcca ccgtggattc aaccatgcgg tacgtgaaat cgcaacagga
    19921 cgagtagact tcaccagcca gaaccatggt tatgcagtca gccgcgagga tttgccagag
    19981 cacttgatta ttacccacga agaaatcaat gacaagtcag tggaaggtgt gcgccacaga
    20041 taccaacctg ctttctctgt tcaataccac ccagatgcag ctcctgggcc acacgacgct
    20101 agctacctat ttgacgagtt tatcgagatg atggaagttt ttaaacaatc aaactaagaa
    20161 tgagtaaaag ctcgtcggag aatttatgta actgaacatg gacggaaagc tcagaattta
    20221 gagaaaccaa cttggattgt caatccttcc ttgatttcct aaaattcaat cgctttctag
    20281 tcgtcctttg tatcttattt aatgtcgccc tgagaggcga cgaatagaaa ggagaagata
    20341 cattgttcgc ggaagtgaac acgccctaag aactgtgtga aaaagataaa catcgtcttg
    20401 acgctgaagg cgtctgcgcc gagtttccta ttttcactgt gttctttacg ggctttgtat
    20461 cataaactat gcctaaacgt actgatattc aaaaaattat ggtgattggt tctggtccga
    20521 ttattattgg tcaggctgct gagtttgact acgctgggac tcaggcttgc ttgtcgttga
    20581 aagaggaagg ttatgaggtt gttttggtta actcaaatcc tgcaaccatc atgacggaca
    20641 aggaaattgc tgacaaggtt tacattgaac cgattacact tgagtttgtg acacgtattc
    20701 ttcgtaagga acgtccagat gccttgctac caacactcgg tggtcagaca ggtctcaaca
    20761 tggccatgga attgtctaaa aatggtatct tagatgagct tggcgttgaa cttctgggta
    20821 ccaaattatc tgccattgac caagcggagg accgtgacct ctttaaacaa ttgatggaag
    20881 agcttgaaca acccattcca gaatctgaaa ttgttaacac agtagaagaa gcagttgcct
    20941 ttgcagcgac aattggctac ccagtcatcg ttcgtccagc ctttaccctc ggtggtactg
    21001 gtggtggtat gtgtgccaac gagaaagaat tgcgtgaaat cactgaaaat ggtttgaaat
    21061 tgtcacctgt tacccaatgt ttgattgagc gttcgattgc cggtttcaag gaaattgaat
    21121 acgaagtgat gcgtgactca gctgacaatg ccttggttgt ttgtaacatg gaaaactttg
    21181 acccagttgg gattcacacg ggggattcca ttgtatttgc ccctgcgcaa accatgtcag
    21241 actatgaaaa ccaaatgctt cgtgatgcga gcttgagcat tattcgtgcc ctcaagattg
    21301 aaggtggatg taatgttcag ctagctcttg atcctaacag cttcaagtat tatgttatcg
    21361 aagtaaaccc tcgtgtatca cgttcgtcag cccttgcttc taaagcgaca ggatatccga
    21421 ttgctaagtt ggctgccaag attgcagtag gtttgacctt ggatgaggtt ataaacccag
    21481 ttacaggttc aacctatgcc atgtttgaac cagcccttga ctacgtagtt gctaagattc
    21541 cacgtttccc atttgacaag tttgaaaagg gtgaacgccg tctcggtaca caaatgaagg
    21601 cgactggaga agtcatggca atcggtcgta acatcgagga atctcttctc aaggcctgcc
    21661 gctcccttga aattggggtg caccacaatg aaatacctga acttgcagca gtttctgatg
    21721 atgccttgat tgaaaaggtt gtcaaagccc aagatgaccg tctcttctac gtatcagaag
    21781 caattcgtcg tggctacaca cctgaagaaa ttgcagagct tacaaaaatt gatatcttct
    21841 atcttgataa actcttgcat atctttgaaa ttgagcaaga attgggtgct catccacaag
    21901 atctagaagt tttgaaaaca gccaaactta atggtttttc agaccgtaag attgctgaac
    21961 tctggggaac gactgatgat caagttcgcc aacttcgctt ggaaaacaag attgttccag
    22021 tttataagat ggtagacact tgtgcggcag agttcgactc cgaaacgcca tatttctatt
    22081 caacctatgg ttgggaaaat gaatctatca gatctgataa agaatctgta cttgtcctag
    22141 gttcaggtcc aatccgtatt ggtcaagggg ttgagtttga ctacgcaacc gttcactctg
    22201 ttaaggctat ccaggcagct ggttatgaag ctatcatcat gaactcaaac ccagagaccg
    22261 tttcaacaga cttctctgta tcagataagc tttactttga gccattgaca ttcgaagatg
    22321 ttatgaacgt cattgacttg gaacaaccaa agggagttat cgttcagttc ggtggtcaaa
    22381 cagccatcaa ccttgcggag ccattggcaa aagcaggtgt gaccatcctt ggtacacagg
    22441 ttgctgacct agatcgtgcc gaagaccgtg acctcttcga gcaagctctc aaagaattgg
    22501 atattccaca gccaccagga caaacagcta ccaatgaaga agaagcagct cttgcagctc
    22561 gcaagattgg cttcccagtt cttgtccgcc catcttatgt acttggtgga cgtgccatgg
    22621 aaatcgttga aaacgaagaa gaccttcgtt cttacatgcg aactgctgtt aaggctagtc
    22681 cagaccaccc agttcttgtc gactcttata tcgttgggca agagtgcgaa gttgatgcca
    22741 tttcagatgg taaaaatgta ctcattcctg gtatcatgga gcatatcgaa cgtgctggtg
    22801 tccactcagg tgactcaatg gctgtttacc caccacaaac cttgtcgcaa aaggttcagg
    22861 agaccatcgc agactacacc aaacgcttag caatcggtct tcactgcctt ggaatgatga
    22921 acatccagtt tgttatcaag gatgaaaaag tctacgttat tgaggtcaat ccacgtgcca
    22981 gccgtactgt tccattccta tctaaggtaa ccaatattcc tatggctcaa gtagcgacca
    23041 aactcattct tggtcaaagt ttatcagaac ttggctacca aaatggactt taccctgaaa
    23101 gcacccgtgt tcatatcaag gcacctgtct tctcctttac caaactagct aaggtagaca
    23161 gcttgctcgg tcctgaaatg aagtcaacag gtgaagttat gggttctgat gctactttgg
    23221 aaaaagctct ctataaagcc tttgaagctt cttatctaca cttgccaact tttggtaatg
    23281 tcgtctttac catcgctgat gatgccaaag aagaagcctt gaacttggct cgtcgtttcc
    23341 aaaacattgg ttatggaatc cttgcgacag aagggacagc agccttcttt gctagccatg
    23401 gcttgcaagc ccaacctgtt ggtaagattg gtgatgacga taaggatatc ccaagttttg
    23461 tacgcaaagg aagaattcaa gctatcatta acacagtagg aacaaaacga actgctgacg
    23521 aagatggtga gcaaattcgt cgttcagcca ttgaacacgg ggtgcccctc ttcacagcgc
    23581 tagatacagc taatgccatg cttaaggtac ttgaaagtcg tagctttgtt acagaagcga
    23641 tttaaataga aaaataagat atagcagact gaatttagaa cagtacacag gaatactaaa
    23701 atatttctag aaattaattt gaattttcta attgatttgt tcgcatctta tttcaatcta
    23761 ctatagaaaa aagtctttaa aattataaaa cgcatcatat caaggttttt caaaaacctt
    23821 gatatgatgc gttttattgt gggaatatgt atttcatttt ctactaaaat tatgtttttg
    23881 aataacctct atcttagtag tttgtataat ccccctcaat cagtttttgc gataagcttt
    23941 aatgctatga ctataccact cttgcatttc ttttgatggt ggtgtcatat aatcgccata
    24001 catctgggtt aaaaattggt catatttttt gggaacaggc aacatacggc cctcaaactc
    24061 agttaaaatc agttctttaa aggtatcaac tgggaagatt tctttcatcc cttccttacc
    24121 gatcccaact cctccttcat attgaggaat gttggttaca gcatttttga ctagttgatc
    24181 aattttcttg taaaagtagc gaggattgac aaatcggaga gcgtaccagc tacataatct
    24241 aagaaaatct tttagtttgc tatcaccgtg aactgctcgt gattttttga tgtaagctag
    24301 ttgacgaagg gccacatact tatagctctt gtcgacaatg ctcaagtctg taaattgatc
    24361 aattgggaag acatcgatga aaaggctgat atcatgacgc ttgtacttaa catggtcttc
    24421 tataacagta gaagtatcca aaatcgatgc gaaattatgg aagtaccaag aagatgtatc
    24481 gtaggaaaga accttgtagc gagggtgatt ttcttcttca ataatcttca gtaaacgctc
    24541 ataatcctca cgataaaggg aaatatcaat atcatcatcc caaggaatca tacctttgtg
    24601 gcggatggct ccaagcatgg ttccataact gagaaaataa ggaatatcat gtttcttaca
    24661 agtctcatca atatagtcca gcagggctag ttgaatttct ttaatttctt ttttttctaa
    24721 atattgcatc ctaatcctcc aatttataag cgtgaaattc atgactgtag aagcgttttt
    24781 cttctggtgg tagggtcata taatctccat aaaattgtgt caaaatagta tcaaattttt
    24841 caggtgcagg aaggcttaaa ttctcaaagg gtaaatcgat tgttttatca aaggtagcac
    24901 ttgggaagac ttccttttcc ttaaattttg aaggaataaa agccatatac tgcccatttt
    24961 cacgactata tttttgaatt tctttctcga ttttatttgc aaaataacga ggagaaacca
    25021 gtcgaaggag caaccaaaag gctgttcgta tccaatcttt taaaaggcta tccttataga
    25081 caatattttt atgtttactg aaagacagca gtttgaagct ttctagttta taacaagtat
    25141 caatgacctt aggatcatca aagcgatcca tagggaaaat atcgataaag ataccagact
    25201 cataggtttt tgtatttcga gtatcaataa ttttagtcgt actgtcggtt atcttgataa
    25261 agttgttaaa gtagttctta tcagtttcta aggataggag cttatacttg cttttttcct
    25321 tttgaaaaat gttaataaat cgttggtagt cttctctagg catggataaa tcaatatcgt
    25381 cgtcccaagg gataaagccc tcatgtcgaa ccgccccaat cagagtaccg tagttaataa
    25441 tatagttgat attgtgcttt ttacagagag tatcaatata attcaaaatt tctaattcaa
    25501 tttgtttggc atcttcaacg gttagttgtt tcattttaaa ctcctaagat tttttaaatt
    25561 tattttttaa ggctaggaca tggtttaaaa attcatagaa aatgctatct tttgtgaaga
    25621 caagtagact aatataagag atagctgata gcaagacaat caaaccagta ttaatcaaaa
    25681 atggcaaatt aatgaccata tccacaggat acacgaaatt aatcaggaaa taaattgcta
    25741 caaaggaaag tgaaaagaga gagtatcgaa cagtatagct aaagatatgt cccaagtgga
    25801 tgagttgttt tctatggatg aaaatgatat agaaaacaag tagagaagcc tctgataaca
    25861 tagttgtcag taagtagtat tcgggagcca cgatatggtt gaaaaagagg agactattca
    25921 agcccaaatt gagtagccca gcaaagactg tatagactgt gatacgtttt tcatagccat
    25981 tggtaaagag aatttgggaa ccaagaatgg tatctaaggc caggataatc gtacgaaaag
    26041 cgaagagaga ggtcaagatg tcgcctccga tatatttttc actaccgtaa agtaggatgg
    26101 catttggtcc taaaaccatg agtccaaaac tcagtggaat gataaagaag ttaaagattc
    26161 gactacctct attaaccaga gaaacatagg cttctttgtc tcctttcccc agatagtaac
    26221 tgagacgagg cacactcact ccaattgcac ctgttacaac cccagctata acggtcacaa
    26281 ttcgctgagc tatggtatag taactaacgt tgacatcaat ccctgtttta acgaggaaga
    26341 ggcgatctaa aaaagtgaag agcatattgg cattggcaaa gactaacatg gctgtcagag
    26401 ggagaaagag tggtttaaaa tcacttaggt gaatcttaac aagtttgatg tctcttttaa
    26461 tccaaaaata actaatcagg tagttaatca gcgtcgataa actcatcaca agtgtataga
    26521 caacaatatc gtgttcattt ttaacaaata agaaaataga gaccagcatc aggatacgga
    26581 tgaaggcagt tttgtaaaag agaaaactgt aattttccag agcttcattg acccattcga
    26641 ttgaaaaaat ctgggcaatg agttgaatcc ccataacaag gtagaccttt ttgacgattg
    26701 gattatcagt aaagaagaga ggataggcta ggatatagac agcagtggtc aaaatcgtac
    26761 aagcgatgca caaataaaaa agactagaaa aggttctgtt aagatctttt ttgttatcct
    26821 tgacattact gatagccctt aaaccgtagt tatagacacc ataagttgca aagggcaaga
    26881 aaaatgacaa aatagtgtcg actgagttga agtaaccata gtcagttcgg tccaagacac
    26941 gcgcgacata ggttccagtt aggatgggaa aaataatatt caagacacga attcccatgt
    27001 aagatagagc atttaatttt atacttttca ttcaatttac ctcgtttttc attatatcat
    27061 aaagttagct aataagaaat gaagggcagt aagtcaagta atcactttga agtttcaaat
    27121 cttaagtttt aagttttctt taaggaaagt atattattct gaaggactct aaaatttcgc
    27181 agccatttat tagtaattgc tacagaattc ctagtcatta ctagaaatgg actagtttct
    27241 ttgaataata gaactgcata attctcctat tctagaaggg gaggaccagt atttctttta
    27301 tgataggact agattgtggt ataatagaga gaataagttt ttttagtaag acaaaggaga
    27361 aaatagatga tttatgcagg aattcttgcc ggtggaactg gcacacgcat ggggatcagt
    27421 aacttgccaa aacaattttt agagctaggt gatcgaccta ttttgattca tacaattgaa
    27481 aaatttgtct tggagccaag tattgaaaaa attgtagttg gtgttcatgg agactgggtt
    27541 tctcatgcag aagatcttgt agataaatat cttcctcttt ataaggaacg tatcatcatt
    27601 acaaagggtg gtgctgaccg caatacaagt attaagaaaa tcattgaagc cattgatgct
    27661 tatcgtccgc ttactccaga ggatatcgtt gttacccacg attctgttcg tccatttatt
    27721 acacttcgca tgattcagga cagtatccaa cttgcccaaa atcatgacgc agtggacaca
    27781 gtggtagaag cggttgatac tatcgttgaa agtaccaatg gtcaatttat tacagatatt
    27841 ccaaatcgtg ctcaccttta tcaaggacaa acacctcaaa cattccgttg caaggacttc
    27901 atggaccttt atggatctct ttctgatgaa gagaaggaaa tcttgacaga tgcatgtaaa
    27961 atctttgtga tcaaaggaaa agatgtggcc ttggccaaag gtgaatactc aaatctgaag
    28021 attacaaccg taacagattt gaagattgca aaaagtatga ttgagaaaga ctagtaaaat
    28081 gattaatcaa atttatcaac taactaagcc taagtttatc aatgtcaaat atcaggaaga
    28141 ggctattgac caagagaatc atatccttat ccgtcccaac tacatggctg tctgtcatgc
    28201 ggatcagcgt tactatcagg gaaaacgtga tcccaagatt ttgaataaaa agcttccaat
    28261 ggcaatgatt cacgagtcat gtggaaccgt catttctgac ccgaccggaa cctacgaggt
    28321 tggtcaaaaa gttgtcatga ttcccaatca gtctcctatg cagagtgatg aagaattcta
    28381 tgaaaactac atgacaggga cccatttctt gtctagtgga tttgatggct ttatgagaga
    28441 gtttgtttct ctccctaaag atcgtgtggt ggcttatgat gctattgaag atacggttgc
    28501 agccattaca gagtttgtca gtgtgggcat gcacgctatg aatcgtctat tgactcttgc
    28561 tcatagcaag cgggagcgga tcgccgttat tggagatgga agtttagctt ttgtggttgc
    28621 caatattatc aactatactt tgccagaagc agagattgtg gttattggtc gtcattggga
    28681 aaagttggaa ctcttctcat ttgccaaaga atgctatatt acggataata ttcctgaaga
    28741 gttggccttt gaccatgctt ttgaatgttg tggtggtgat ggtactggac cagctattaa
    28801 tgacttgatt cgctacattc gtcctcaggg aacgattctc atgatgggag ttagcgaata
    28861 taaagtcaat ctcaatactc gcgatgcctt agaaaagggc ttgattttgg ttgggtcatc
    28921 tcgttctggt cgcattgatt ttaaaaatgc tatccaaatg atggaagtca agaaatttgc
    28981 caatcgtctt aaaaatatcc tttatctaga agaacctgta agagaaatta aagatattca
    29041 tcgtgtcttt gcaaccgatt taaacacagc ctttaaaaca gtgtttaagt gggaagtata
    29101 agtactggag gttaattgtg gagaaaatca ttaaagaaaa aatttcttcc ttacttagtc
    29161 aagaagagga agtcctcagt gttgaacaac tgggtggaat gaccaatcaa aactatttgg
    29221 ccaaaacaac aaataagcaa tacattgtta aattctttgg taaagggaca gaaaagctta
    29281 tcaatcgaca agatgaaaag tacaatcttg aactactaaa ggatttaggc ttagatgtaa
    29341 aaaattatct ttttgatatt gaagctggta tcaaagtaaa tgagtatatc gaatctgcga
    29401 ttacgcttga ttcaacgtca atcaagacca agttcgacaa aattgctcca atattacaaa
    29461 ctattcatac gtctgctaag gaattaagag gagaatttgc tccttttgaa gaaatcaaaa
    29521 aatacgaatc cttgattgaa gaacaaattc cttatgccaa ctatgaatct gttagaaatg
    29581 cagtcttctc cttagagaaa agactggctg acttaggtgt tgacagaaaa tcttgtcata
    29641 tcgatttggt gcctgaaaac tttatcgaat cacctcaagg acgactttat ttgattgact
    29701 gggaatattc atcaatgaat gatccaatgt gggatttggc tgccctcttt ttagagtctg
    29761 aattcacttc ccaagaggaa gaaactttct tatctcacta tgagagtgac caaacaccgg
    29821 tttctcatga aaagattgct atttataaaa ttttacaaga tactatttgg agtctatgga
    29881 ctgtctataa ggaagagcaa ggtgaagatt ttggtgacta tggtgtgaat cgttaccaaa
    29941 gagctgttaa aggtttggct tcttatggag gttcagatga aaagtaaaaa cggagttcct
    30001 tttggccttc tctcaggtat tttctggggc ttgggtctaa cggttagtgc ttatatcttt
    30061 tcgattttta cagatttgtc accctttgtg gtggctgcag ctcatgattt tttgagcatc
    30121 tttatcttac tagcttttct cttggtaaaa gaagggaaag ttcgcctctc aattttctta
    30181 aatattcgca atgtcagtgt tatcatcgga gccttgctag caggccctat cggtatgcag
    30241 gccaatcttt atgcagttaa gtatatcgga agttctttag cttcatctgt atcggctatt
    30301 taccctgcga tttcagttct attggctttc ttctttttga agcacaagat ttcgaaaaat
    30361 actgtatttg ggattgtctt gattattgga gggattattg cccagaccta taaagttgaa
    30421 caggttaatt ctttctacat tgggattctt tgtgctttgg tttgtgctat tgcatgggga
    30481 agtgagagtg ttcttagctc ttttgccatg gaaagtgaat tgagtgaaat cgaagccctc
    30541 ttaatccgtc aagtaacttc gttcttgtcc tatcttgtga ttgtgctctt ctctcatcag
    30601 tcatttactg cagtagccaa tggacaattg ctaggtctca tgattgtttt tgcagccttt
    30661 gatatgattt cctacttggc ttattatatc gctatcaatc gcttgcaacc agccaaggct
    30721 acaggcttga acgtgagcta tgtagtatgg acggtcttgt ttgcagttgt tttcttgggt
    30781 gcaccgctag atatgctgac cattatgacg tcacttgtcg tcattgctgg agtttatatt
    30841 attattaaag aataaaggag attcgtgtga aagccatcat cttagcagcg ggattgggaa
    30901 ctcgcttgcg tcctatgact gaaaataccc ctaaagcctt ggttcaggtt aatcaaaaac
    30961 ctttgattga gtaccaaatt gagtttctca aagaaaaagg aatcaatgac atcatcatca
    31021 ttgttggtta tcttaaagaa caattcgatt acttgaaaga gaaatacggt gttcgtctcg
    31081 ttttcaatga taaatacgct gactacaata acttttactc tctctatctt gtaaaagaag
    31141 aattagccaa tagttatgtt atcgatgccg ataactatct ctttaaaaat atgttccgca
    31201 atgatttgac acgttctact tattttagtg tctatcgtga agattgtacc aacgaatggt
    31261 tcttggtcta tggagatgac tacaaggttc aaaacattat tgttgatagc aaggcaggtc
    31321 gcatccttag tggtgtatcc ttctgggatg ctccaacagc agaaaaaatt gttagcttta
    31381 tcgataaggc ttatgcaagc ggcgaatttg ttgatctcta ttgggacaat atggttaagg
    31441 ataacatcaa agagctagat gtctatgttg aagaattaga aggcaatagc atttatgaga
    31501 ttgatagtgt ccaagactat cataaattag aagaaattct taaaaacgaa aattaaaagc
    31561 ttccaacatc tgacaaaata gtcggatgtt tttttgattt tttacgaact tttacgaata
    31621 gatagatgag tagaaaaaga aatggagtta tttatgaaaa tcacaaacta tgaaatctat
    31681 aagttaaaaa aatcaggttt gaccaatcaa cagattttga aagttctaga atacggtgaa
    31741 aatgttgatc aggagctttt gttgggtgat attgcagata tatcaggttg ccgtaatcca
    31801 gccgttttta tggaacgtta ttttcagata gacgatgcgc atttgtcgaa agagtttcaa
    31861 aaatttccat ctttctctat tttagatgac tgttatcctt gggatttgag tgaaatatat
    31921 gatgcgcctg tacttttatt ttacaaggga aatcttgacc tcctgaaatt cccgaaggta
    31981 gcggtcgtgg gcagtcgtgc ttgtagcaaa cagggagcta aatcagttga aaaagtcatt
    32041 caaggcttgg aaaatgaact ggttattgtc agtggtctgg ccaagggcat tgacacagca
    32101 gctcatatgg cagctcttca gaatggcgga aaaaccattg cagtgattgg aacaggactg
    32161 gatgtgtttt atcctaaagc caataaacgc ttgcaagact acatcggcaa tgaccatctg
    32221 gttctaagtg aatatggacc tggcgaacaa cctctgaaat ttcattttcc tgcccgtaat
    32281 cgcatcattg ctggactttg tcgtggtgtg attgtagcag aggctaagat gcgttcaggt
    32341 agtctcatta cgtgtgagcg agcaatggaa gaaggacgcg atgtctttgc tattcctggt
    32401 agcattttag atggactatc agacggttgc catcatttga ttcaagaagg agcaaaattg
    32461 gtcaccagtg ggcaagatgt tcttgcggaa tttgaatttt aaaaatgacc taagctagaa
    32521 ttctaagaaa aaatcaattt taagagaaaa tgaacccaac atttccataa taaaacgcat
    32581 attagcaagt ttttaacact tgataatatg cgttttttct aagtggatta gtagagtaga
    32641 ggatttttct catataatac tcttcgaaaa tctcttcaaa ctacgtcagc ttccatctgc
    32701 aacctcaaaa cagtattttg agctgacttc gtcagtctta tctacaacct caaagcagtg
    32761 ctttgagcaa cctgtggcta gcttcctagt ttgcgctttg attttcattg agtataaggg
    32821 aaagtatagt gaattgaaat aagatgtgaa caactctatc aggaaagtca aattaattta
    32881 tagaaatatt ttagcagcca aggtgcactg ttatagattc aatacactat aatttagtgt
    32941 aattgagaaa ggagaaatga ttgtgattga tgttggctag gttatgttca atgattccta
    33001 ccgtctcaaa tcttgtcagt aaggaaaaat aaattcttca aaagtagaga ttacaaggct
    33061 tgtttaagaa agaattcaaa gaccttgaca aataaaaata aaatggttat tataaaaaat
    33121 ggtctgaaat agatgatgat acttttcgaa aatcttttta cgtcagctca gctttgcctt
    33181 gctgtgtttt gagcaagcta cggttagctt ccgagtttga ttttcattta ctagaaatga
    33241 aactgatgag agatatcagt agacatttga gtcaggatat tatggaaaat gataaaaaga
    33301 gctcgtgaga ttggcatatc agactactaa agtattgagt ttgttaggat tttagcgact
    33361 agttagctgg gaaaggaaga tatttgtgac aaataataaa ctgtattcgt tgatagaatt
    33421 tagaaataaa atatatgaag aattagaact ttccagaagt gatttagcga ttttactatg
    33481 tgccatgctt atcgcctcta tcggattaaa tatggattcg actcccgtga ttattggagc
    33541 catgttaatc tctcctttga tgacacctat tctgggagtg gggctctctc tagctatatt
    33601 tgattttaaa ttgttaagaa aatcttttaa aatattagct attcaaattc ttgccagttt
    33661 aatagcttca acactttatt tttatctttc tcccatttcg tatgctagtt cggaaattgt
    33721 tgctagaacc tctccgacta tttgggatgt tctcattgct tttgtaggag ggatagcagg
    33781 tattattggt gctaggaaaa aagagaccaa taatattgtt cctggtgttg ctattgcaac
    33841 cgccttgatg cctcctcttt gtacagtagg ttatgctatt gcttctgcta atctaaaatt
    33901 tatcataggc tcctcttacc tattcctcat caattgtagc tttattgtca ttgcgactta
    33961 tataggtgtt aggttgatga tggttaagaa acattatttt aaagataatg aagaagactc
    34021 taaaatgcgt aggattttgc ttctagttgc tgttttgctg atgattccga gtttcatctc
    34081 tgcaacgact ttagtgagag aaacgttgaa aaaagagtcc cttaagaaat ttatatcaga
    34141 gcagtttcag gggcataata ttttgaaaaa aacctattct aaaaagactc ataccctaaa
    34201 gctaaccatt tcaggaaatt atttgacaga agaagaactc gatatgattt caagtaagag
    34261 aggtgactat ggtttaagtg atgtttctgt tcaagtttca caattgtctg attcagaaca
    34321 acttagtaag gaagaactgg tggagtattt cttccagtat atcaaggata aggaagcaaa
    34381 agaaaaggaa aaagctaata agttttatac agagtctgag gagcaataat ttcttgagaa
    34441 tagctggttt ctctcgtgag tcttctatgt atatcaaagg aagactgagg ttttaagtat
    34501 aaaacttttc ttctattata gtagctaagt cttgacaggg ttcaaaaaat ggtttacact
    34561 ttataaagtt tattactttg aaaaggtgtg atactgtggc tacggcaaca aaaaagaaaa
    34621 aatcaacagt taaaaaaaat ctagtcatcg tggagtcgcc tgctaaggcc aagacgattg
    34681 aaaaatatct aggcagaaac tacaaggttt tagccagtgt cgggcatatc cgtgatttga
    34741 agaaatccag tatgtccgtc gatattgaaa ataattatga accgcaatat atcaatatcc
    34801 gaggaaaagg ccctcttatc aatgacttga aaaaagaagc taaaaaagct aataaagttt
    34861 ttctcgcgag tgacccggac cgtgaaggag aagcgatttc ttggcatttg gcccatattc
    34921 tcaacttgga tgaaaatgat gccaaccgtg tggtcttcaa tgaaatcacc aaggatgcag
    34981 tcaaaaatgc ttttaaagaa cctcgtaaga tcgatatgga cttggtcgat gcccaacaag
    35041 ctcgtcggat cttggatcgc ttggtagggt attcgatttc gcctattttg tggaagaagg
    35101 tcaagaaggg cttgtcagca ggtcgcgttc agtccattgc ccttaaactc atcattgacc
    35161 gtgaaaatga aatcaatgcc ttccagccag aagaatactg gacagttgat gctgtcttta
    35221 aaaagggaac caaacaattt catgcttcct tctatggagt agatggtaaa aagatgaaac
    35281 tgaccagcaa tgacgaagtc aaggaagtct tgtctcgtct gactagtaaa gacttttcag
    35341 tagatcaggt ggataagaaa gagcgcaagc gcaatgctcc tttaccctat accacttcat
    35401 ctatgcagat ggatgctgcc aataaaatca atttccgtac tcgaaaaacc atgatggttg
    35461 cccaacagct ctatgaagga attaatattg gttctggtgt tcaaggtttg attacctata
    35521 tgcgtaccga ttcgactcgt atcagtcctg tagcgcaaaa tgaggcggca agcttcatta
    35581 cggatcgttt tggtagcaag tattctaagc acggtagcaa ggtcaaaaac gcatcaggtg
    35641 ctcaggatgc ccatgaggct attcgtccgt caagtgtctt taatacacca gaaagcatcg
    35701 ctaagtatct ggacaaggat cagctcaagc tatataccct tatctggaat cgttttgtgg
    35761 ctagccagat gacagcggcc gtttttgata ccatggctgt taaattgtct caaaatggag
    35821 ttcaatttgc tgccaatggt agtcaggtta agtttgatgg ttatcttgcc atttataatg
    35881 attctgacaa gaataagatg ttaccggaca tggttgttgg agatgtggtc aaacaggtca
    35941 atagcaaacc agagcaacat ttcacccaac cgcctgcccg ttattctgaa gcaacactga
    36001 ttaaaacctt agaggaaaat ggggttggac gtccatcaac ctatgcgcca accattgaaa
    36061 ccattcagaa acgttattat gttcgcctgg cagccaaacg ttttgaaccg acagagttgg
    36121 gagaaattgt caataagctc atcgttgaat atttcccaga tatcgtaaac gtgaccttca
    36181 cagctgaaat ggaaggtaaa ctggatgatg tcgaagttgg aaaagagcag tggcgacggg
    36241 tcattgatgc tttttacaaa ccattctcta aagaagttgc caaggctgaa gaagaaatgg
    36301 aaaaaatcca gattaaggat gaaccagctg gatttgactg tgaagtgtgt ggcagtccaa
    36361 tggtcattaa acttggtcgt tttggtaaat tctacgcttg tagcaatttc ccagattgcc
    36421 gtcataccca agcaatcgtg aaagagattg gtgttgagtg tccaagctgt catcagggac
    36481 aaattattga gcgaaaaacc aagcgtaatc gcctattcta tggttgcaat cgctatccag
    36541 aatgtgaatt tacctcttgg gacaagcctg ttggtcgtga ctgtccaaaa tgtggcaact
    36601 tcctcatgga gaaaaaagtc cgtggtggtg gcaagcaggt tgtttgtagc aaaggcgact
    36661 acgaggaaga aaagattaaa taagaggagg ggcccgaaag taaatttcag gctccttttg
    36721 gttagaactt gacaaaatac atcattttat gcgaaactag aagaagatta ttttatactc
    36781 aatgagaatc aaagagcaaa ttagaaagct agtcgcaggt tgctcaaagc actactttga
    36841 ggttgaagat ggaagctgac ctggtttgaa gagattttcg aagagtatta actaggagaa
    36901 gttatgcgta ttatctatct aattattggt tttttatcgc tgaccttggc tattgttggg
    36961 gttgttttac ccttgttgcc tacaacacct ttccttttgt tgtctattgc ttgtttctcc
    37021 agaagttcca agcgattcga agattggctt tatcatacca agctctatca agcatatgta
    37081 gctgattttc gtgagaccaa gtctattgcg cgtgaacgaa agaaaaaaat catcgtctct
    37141 atctacgtct tgatgggaat ttctatttat tttgcacctc ttttaccagt caaaatcggt
    37201 ctgggtgctt tgaccatctt tattacttat tatctcttca aggtcattcc agacaaagaa
    37261 tagttaaaac agtagttatt tgccttgata aaattgaaag catattcata acaatatgat
    37321 ataataaaat tgaagtaata ttcaaggaga atcaaatgat ttacgaattt tgtgctgaaa
    37381 atgtgacttt acttgaaaaa gcgatgcagg ctggagctcg tcggattgaa ctctgtgata
    37441 atctagcagt tggtgggaca acacccagct atggagtgac taaggcagcg gttgaactgg
    37501 cagctaacta cgatacaacc atcatgacca tgattcggcc acgtggtggt gactttgtct
    37561 ataatgacct agaaattgct atcatgctag aagacattcg tttgactgct caggctggaa
    37621 gtcaaggggt tgtatttgga gctttaactg ctgataaaaa gttggataag cctaatctgg
    37681 aaaagttaat tgctgcatca aaaggaatgg aaattgtctt tcacatggcc tttgatgaac
    37741 taagtgatga agatcaaccg gaagctattg actggctcag tcaagccggt gtcactcgta
    37801 tcctaactcg tgctggtgtg tctggcgact ccttagaaaa acgttttgtt cactatcaca
    37861 gaattttgga gtacgctaaa ggtaaaattg aaattctacc aggtgggggg attgaccttg
    37921 aaaaccgtca aacctttatc gaccaggtgg gggtaacaca attgcatggt actaaggttg
    37981 ttttttaaaa aatagaaagg aactgctagc tttgggtagc agttttcact tatgtttgaa
    38041 atttttaaat cctatcaatt taatcaagaa aaggctcatg attatggttt tatagaaaat
    38101 agcgaagtct ggacatatag ttgccagatt ttgcaaggtg actttgtcat gactgtgtcc
    38161 atcactgctg ataatgtgaa ctttcaagtc tttgaccaag agactggtga cctctatcct
    38221 cacgtttata tggaaagcat gaggggaagt tttgtcggaa atgtccgtga ggcttgtctg
    38281 gagattcttt accagattcg gaaggcttgt tttgatgtgc aagattttat ctgtcatcag
    38341 actaagcgta tcatgactca agttcaggaa aagtatggaa accagttgga gtatctgtgg
    38401 gaaaaatcgc ctgatacagc tgtattgcgc catgaaggca atcaaaagtg gtatgccgtc
    38461 ttgatgaaaa tctcttggaa taagctggaa aagggcagag aaggacaagt ggaagcagtc
    38521 aacctcaagc atgaccaagt agctaatttg ctttcacaaa aggggattta tccagccttc
    38581 catatgagca agcgctactg gattagtgtg tcccttgatg atactttatc agatgaagaa
    38641 gtactggaat tgatagaaaa aagttggaac ttaacctcta aaaaatgaaa tattttaata
    38701 attttcatga actttcaatt agctaaatat tctttactga agagattttt agaaaatata
    38761 ggatttacca cactagagga atatggtgcc atcttcaaat acctgattga gaatgtcaag
    38821 acggatcgtc agatcatcta ttcgcctcac tgtcatgatg acctcggaat ggcagtggca
    38881 aatagccttg ctgctgtcaa gaatggtgca ggacgtgttg aagggactat caatggtatt
    38941 agggagcgag ctgaaaatgc tgctttggaa gaaattgcag tggctctcaa tattcgccaa
    39001 gattactacc aagtagaaac cagtattgtc ctaaatgaga ccatcaatac gtcagaaatg
    39061 gtttctcgct tctctggtat tccagttcct aaaaacaaag ccgtcgttgg tggcaatacc
    39121 ttctcccacg aatctggtat tcaccaagat ggagtcctta aaaatcctct cacttatgag
    39181 atcatcacac ctgaattggt tggtgttaag attctgcttg gaaaattatc tggtcgccat
    39241 gcttttgttg agaaactgag agaattggcc ctagatttta cagaagagga tatcaaacca
    39301 ctctttgcta agttcaaggc actggtcgat aagaagcaag aaatcacaga tgcagatatt
    39361 cgagctttgg tagctggaac catggttgaa aatccagaag gcttccactt tgatgattta
    39421 caacttcaaa ctcatgcaga taatgacatt gaagcgctcg ttagcctagc caatatggat
    39481 ggtgagaaag tcgaatttaa tgcgacaggg caaggttccg ttgaagcaat ctttaatgct
    39541 atcgataagt tctttaacca atctgttcgt ttggtgtcct acactatcga tgcggtaaca
    39601 gatggaatcg atacccagga tcgggttttg gtcactgttg aaaacagaga tacagaaacc
    39661 atctttaatg cagcagggct tgattttgat gtgttgaagg cttctgctat tgtctatata
    39721 aacgctaata cctttgttca aaaagagaat gcaggtgaga tgggacgcag tgtttcttac
    39781 cacgatatgc ctagtgtgta aaggagaagg ctatggcaaa gaaaatagta gctctagcag
    39841 gagacggaat tggcccagaa atcatggagg ttggtttaga agttctggag gctctagctg
    39901 aaaaaacagg ttttgactat gagattgaca gacgaccgtt cggaggtgca gatattgatg
    39961 cagcatgacc tcccttacct gatgaaaccc ttaaggcaag tagggaagca gatgctatcc
    40021 tactagtagc tatcggtagt cctcagtatg atggagcagt ggttcgccct gaacaaggcc
    40081 tgatggctct ccgtaaggaa ctcaatcttt acgctaatat tcgtcctgta aaaatctttg
    40141 acagtctcaa gcatttgtca ctactcaaac tggaacgaat tgctggtgta gactttgtcg
    40201 tggtgcgtga attgacaggc gggatttact ttggagatca tattcttgaa gagcgcaatg
    40261 cgcgtgatat caacgactat agctatgagg aagtggagcg gattattcgc aaagcctttg
    40321 aaattgcaag aaatcgcaga aaaatcgtta ctagtatcga taagcaaaat gttctagcga
    40381 cctcaaaact ctggcggaaa gtagctgagg aagtcgcaca ggatttccca gatgtaacct
    40441 tggaacatca gctggtagac tcagctgcta tgcttatgat taccaatcct gctaagtttg
    40501 atgttattgt aacggagaat ctttttggag atattttatc tgatgaatca agcgtcttat
    40561 ctggtacact tggggttatg ccatcagcca gtcattctga aaatggacca agtctctatg
    40621 aacctattca cagttcagca cctgatattg caggtcaagg aattgccaat cctatttcca
    40681 tgattttatc agtttccatg atgttgagag atagtttcgg acgttatgag gatgcagagc
    40741 gtatcaaacg tgctgttgag acaagtctgg cggcaggaat tttaacgaga gatataggag
    40801 gtcaggcttc aacaaaggaa atgacggaag ctattattgc aaggttatga agttagacga
    40861 aaaaattact ctagtccttt tgatttggaa tgtcatcatt ttcttgattt atggtattga
    40921 caaatctaag gcaaggagaa gagtttggcg catccctgag aaaatcttac ttattttagc
    40981 ctttactttt ggtggttttg gtgcctggct agcaggaatc atctttcacc acaagactcg
    41041 aaaatggtac tttaaaatag tttggtttct tgggatggtg accacactag tagccttata
    41101 ttttatttgg aggtaatgga tggcagggtc ttcgagggaa tacgctgctt gggctctagc
    41161 ggactatggt tttaaggtcg tgattgcagg atctttcggt gacattcatt acaataatga
    41221 actcaataat ggcatgttgc caatcgttca gcctagagag gttagagaga aactagccca
    41281 gctaaaacca accgaccagg taactgtgga cttggaacaa caaaaaatca tctcaccagt
    41341 tgaagaattc accttcgaga tagatagcga gtggaaacat aaactcctaa atagtttgga
    41401 tgatatcggt attaccttgc agtatgaaga gttgattgct gcttatgaaa aacaacgacc
    41461 agcctactgg caggattaga aaaaatagaa aaggagatat agtaaactga aataagatgt
    41521 aaacaaatga attggagctt aacatccatt tccagcaatt ttttagaaac tacagtggac
    41581 tattctggat tcaacacatt ataaaattat gacaaaacac attcacaaga aggctacgac
    41641 attttaaaag gtgagggcgg atgtatcgtt tgccctacta aagttggtta cattatcatg
    41701 accagtgaca aggcaggact tgagcgtaag ttcgcagcca aagaacgtaa gcgtaacaaa
    41761 ccaggtgttg ttctctgcgg tagcatggat gaactttgcg ctttagcgca actcaaccca
    41821 gaaattgaag cattctacta aaaacattgg gatgaagata ttcttcttgg ttgtatcctt
    41881 ccttggaaac cagaagcctt tgaaaaactc aaagcatacg gggatggccg tgaagaactt
    41941 atgactgatg tacgtggtac tagctgtttt gttatcaagt ttggaaaagc aggtgaacaa
    42001 ttggctgcca agctttggga agaaggtaaa atggtctacg cctcatctgc ttcaatgaca
    42061 aaacgattga aactcgctat gagcaaggtg taatggtgtc tatggtcgat aaggacggca
    42121 aactcatccc agaacaagga ggagcacgtt caacttcacc agctccagtt gtgatccgta
    42181 aagggcttga cattgatata gtaaaatgaa gtaagagcag gacaaattaa tcaggacagt
    42241 caaatcgatt tctaacaatg ttttagaagt agaggtgtac tattctagtt tcaatccact
    42301 ataaaatcat gatgcacctg tcagatactt ttaactcatg ggactaccgt caggttgagt
    42361 attattagga tagagaagaa gtctagtgtt aaggacatta cagctcataa tactaggctt
    42421 ttttatagaa attcttttct ttttctatag gatatggtat tctatgtaga aaatatatgt
    42481 taataagtaa tgccaatatt taaacatcat tagtaaaagg agttagattg atgaataaaa
    42541 gaaaagttag tttagaagat ttttataaat ggtatagtct aaataaagaa gagttattaa
    42601 ataaggcaac tgttggtgaa aagtttaatg ataaattaaa agaagagttt ctccaggaat
    42661 ggcctttgga taggatttta acaatgtcaa tcgatgaata tgtaatagga aagggacagc
    42721 aaaataagtc tttatgctac gctcttgaga agggaaaata caaaaatcta tttcttggaa
    42781 tttctggtgg ctcagcttca aaatttggta tttattggaa taaaaaaaca aacaaatata
    42841 aagatcaagc taataatgag atttcagagt tggatcagcg attttcaaaa ttaaaatcag
    42901 atttgtatga aattatcaaa gaaggtattc gttttaactt tgaaaatcct atttttgata
    42961 tgaaaagatc aacaaatgaa tttattggtc gttctgctat ggtgacaaaa ttactttgta
    43021 tctatactga gggagatcct ttctttggtg taaatattaa tagtcagaaa gaattttgga
    43081 accactttgt ttctcagaca aatcaaggtg gaccttatct gcaaaatcat aaaataattg
    43141 aactgatgtc caaaacttat cctgagttgg agccatcgaa attaggaact atgctttttg
    43201 agtattctaa gctttttatg gaaaataagg aagacaatag tacaatggat tcatcaaaca
    43261 attttcgtca tcaattaact caatctctat taaagtctcc aaaccttatc cttcgtggtg
    43321 ctcctggcac aggaaagact tatcttgcta aagaaattgc caaagaatta acggatggca
    43381 acgaagatca aatcggattt gtacaatttc acccatcata tgattatacg gattttgtag
    43441 aaggtttaag accagtatca aatggggatg gagctattga gtttaggcta caggacggta
    43501 tttttaaaga tttttgtcag aaagcaaaag aaacccaatt gattggagga caagataatt
    43561 ttgatgaggc ttgggattct tacttagaat atataaatgt tgctgaagaa aaagaatata
    43621 taacaaaaac atcttactta tctgttaata gtagacaaaa tttgtcagta aattatgata
    43681 gtggtgttcc aggatggtca ctacctagca aatatgttta cgagttgtat aaagataaaa
    43741 attataataa gcaagaatac tacaaaagtg gtggaaaaac tgtcctagaa acattgagaa
    43801 agagatttgg tttgaaagac tatgtttccc caacagaaat tgatactgat aagaaattcg
    43861 ttttcatcat cgatgaaatc aatcgtgggg agatttctaa gatttttggc gaactctttt
    43921 tctctatcga ccctggctat cgtggtgaaa aaggaagtgt ttctacccaa tatgcaaatc
    43981 tacacgaaac tgatgaaaag ttctatatcc ccgaaaatgt ttacatcatc ggaactatga
    44041 atgatattga tcgttcagtg gatacctttg attttgctat gcgtcgtcgt tttcgttttg
    44101 ttgaagttac tgccgagggt caagttggca tgttggataa agagctgaat atccatgcag
    44161 aagaagcaaa aattcgtcta agaaacttga acgctgctat cgaaaatgtt caggaattaa
    44221 acagtcatta tcatattgga ccaagttatt ttcttaagtt gaaggatgta gattttgact
    44281 atgaattact ctggtccgat tatattaagc ctctcctaga agactacttg cgaggttctt
    44341 atgatgaggt tgaaactttg gaaactttga aaaaagcatt tgaactgaca aataatgagc
    44401 aaaaagatca ggcagtagct gatgacaatg aaagcgatga aaacgatgat gcggattact
    44461 gataatcaac acaagattat taaagaaaaa tttgttgaag aatatcctaa actaagcaat
    44521 cttcttttag acagaacctt ggaaagtcta tcccaagatg aacgtatttt catttttcca
    44581 aatgatttga ctcatactcc agatttggat aaaaaacaaa agattttgga aacgatcaat
    44641 caggaaatca agacaggaaa tgtgattggt tttcttggat atggtcagga aagattaacg
    44701 atttcctcac gattttctga tgagagtaat gaccattttt tgcattatct cttaaacaag
    44761 gttcttcata tcaatctcac tagtttagat gttgctttgt ctcgtgaaga gaggctttat
    44821 caacttttga tgtatctctt ccccaagtat ctacaagctg ctattcgaaa aggtctttat
    44881 aaggaatatc atcgattttc tcataacgac agtcatgtta agggagtgat tgatgtaaga
    44941 aaccatctca agaaaaatct tcctttcacg ggaaatattg cctacacaac gagagagttc
    45001 acctatgata atcccctcat gcagttggtc cgtcacacta ttgaatacat taagaatcag
    45061 aaaagcattg gtcaaggggt actagataat ctctcaacta gtcgtgaaaa cgtatctgaa
    45121 atcgtgcgtg taacgccctc ttataaacta gctgatcgtg ctaagattat tcggggaaat
    45181 caatctaaac ctatacgtca tgcatacttt cacgagtaca gaaacttaca agaactttgt
    45241 ctgatgatcc taaaccaaga aaagcacggt ttagggtatc aagatcaaaa aatctatggt
    45301 attctctttg atgttgcctg gctttgggaa gagtatgttt acaccttgtt gccaaaaggt
    45361 tttgtacatc ccagaaataa ggataagacg gatggaattt cagtattttc tgttgggaaa
    45421 cgaaaagtat atccagattt ttatgacaga gaacgaaaga ttgttctaga tgcaaaatat
    45481 aaaaaactgg aattgactga aaaaggaatc aatcgtgagg acttattcca gctgatttcc
    45541 tattcttata ttttaaaagc tgagaaggct ggacttgttt ttccgagcaa ggacaaggtt
    45601 attgataatg agatgggaaa cctagcaggt tatggagctt tgttgaagaa atggtctatc
    45661 caaattcctc agaagtcttc atcttatagt gcattttgta aaatgatgga aaattcagat
    45721 tatagtgcat tttgtaaaat gatggaaaat tcagaagaaa attttaaagc gattattgat
    45781 gaagaagtgg ggagaaaata atttcccctc tttcttttat ttttaacaca agtaaaaccc
    45841 gaacaatata tttcaattca taaaataatt tgacaaaaac tgtactttgg tttataataa
    45901 attaaggaaa cgtcggaaaa gacgtagtga tgcgagagca taggtaggtc attacaaaag
    45961 aaacgagaca tcgatatgtt aaatgaattt ccaatttttg attacgaaga tattcaattg
    46021 attccaaata aatgtgtcat taaaagccgt gcagaagcgg atacaagtgt cactttagga
    46081 aatcacacct ttaaactacc tgttgtgcca gcgaatatgc agacgatttt ggatgaaaat
    46141 gtagcagagc aactggctaa aggtggttac ttctacatta tgcaccgttt tgatgaggca
    46201 ggacgcattc cttttattaa acaaatgcac gatcaagggc tcattgcttc catctctgtc
    46261 ggtgttaagg actatgagta tgattttgtt agccagctca agactgatgc tcctgagtat
    46321 atcactattg atattgctca tggtcatgcg gatagcgtga tttctatgat tcaacatatc
    46381 aagaaagaat tgccagatac ctttgtcatt gctggaaatg tgggaacacc agaagctgtg
    46441 cgtgaattgg aaaatgctgg tgcggatgct actaaggtcg gaatcggtcc cggtaaggtt
    46501 tgtatcacca aggttaagac tggttttggt acaggtggtt ggcagttggc tgctctacgc
    46561 tggtgtgcca aggctgcgcg taaaccgatt atcgctgatg gaggaattcg tactcacggt
    46621 gatattgcta agtctatccg cttcggtgct agcatgatca tgattggttc cctctttgca
    46681 ggacacattg aaagtccagg gaaaacgatt gaagtcgatg gtgaacagtt caaagaatat
    46741 tatggttcag cctcacaata tcaaaaaggt gcttacaaaa atgtggaagg caaacgtatc
    46801 ttgcttcctg ctaaaggtca tctgcaagac actttaactg agatggaaca agaccttcaa
    46861 agtgctattt cttatgcagg tggacgtcag gttgctgacc ttaaacacgt tgattatgtg
    46921 atcgtgaaaa actccatctg gaatggggat gcttcccact aagacggggt ctttgaccaa
    46981 aaaacttgtt attagagcaa atttctgtta taataaaaca agtttccacc cttagtgtaa
    47041 tggatatcac gtaagattcc ggttcttgag atgggggttc gattccctca gggtggatgt
    47101 aaacatccta aaaagccttt aatagggctt ttttctttat cctgacccaa atttgccgct
    47161 aaaactgaga atctctgtct aaagaattcc caaatgcttt ccagtcccgt tttagagtga
    47221 ctcagggggc tttttttgat ataataaaaa ggactgttat cagttagaaa gaggttggta
    47281 tgaaagaatt acaaactgta ctaaagaatc attttgcaat cgaatttgca gacaaaaatt
    47341 tactggaaac tgcctttact catacgagtt atgccaatga gcaccgcctc ttaaaaattt
    47401 cacacaatga acgcttggaa tttttaggag acgctgttct acagttattg atttcagaat
    47461 atctatataa aaaatatcct aaaaagcctg aaggtgacct atcaaaactc cgtgctatga
    47521 ttgtccgtga ggagagttta gctggttttg cgcgtgattg ccagtttgac cagtttatca
    47581 agttgggtaa aggggaagaa aaatcaggtg gtcgcaatcg tgacaccatt cttggtgatg
    47641 cctttgaagc ctttcttggt gcccttcttt tggataagga tgtggccaag gtcaaggaat
    47701 ttatctatca agtcatgatt cctaaggttg aagcaggcga atttgagatg attacagact
    47761 ataaaaccca tctccaagag ttacttcagg tcaatggtga tgtggctatt cgttatcagg
    47821 tgatttctga aacagggcct gctcacgata aggtctttga tgtagaagtt cttgttgaag
    47881 gtaagagcat cggtcaaggc caaggtcgtt ctaagaaatt agcagagcag gaagctgcca
    47941 aaaatgccgt tgagaagggg ctggattcat gtatttaaag gaaatcgaaa ttcaggggtt
    48001 caagtctttt gctgataaga ccaaggtcgt ttttgaccaa ggtgtgacgg cagttgttgg
    48061 acccaatgga tctggaaagt ccaatattac agaaagtctg cgttgggctt tgggggagtc
    48121 tagtgtcaag agtctccgtg ggggcaagat gccggatgtc atctttgctg gaacagaaag
    48181 tcgcaaaccg ctcaattatg cttctgtagt tgtgactctg gataatcatg acggatttat
    48241 caaggatgca ggtcaagaaa tcagggtgga acgccatatc tatcgtagtg gagatagcga
    48301 atacaagatt gacggcaaga aagtccgtct gcgtgatatt catgaccttt tcttggatac
    48361 aggtttggga cgagattcct tctctattat ttcccaaggg aaggttgagg agatttttaa
    48421 ttccaagtct gaggaacgac gagctatttt tgaagaagct gctggagttt taaaatacaa
    48481 gactcgcaga aaagaaaccg agagtaaact gcagcaaact caggataatc tggaccgctt
    48541 agaggacatt atctacgagt tggataatca aatcaagcct cttgagaagc aagctgagaa
    48601 tgcccgtaaa tttctagact tagaaggtca acgcaaggct atttacttgg atgtattggt
    48661 tgctcaaatc aaggaaaata aggcagaact agagtcgaca gaagaagagt tggctcaggt
    48721 tcaagaactc ttgatgagtt attaccaaaa gcgtgaaaaa ttagaagaag aaaatcaaac
    48781 tcttaaaaag caacgccaag atttacaggc tgaaatggcc aaagaccaag gcagtttgat
    48841 ggacttgact agtctgatta gtgatttaga aagaaaatta gccctatcga aactggagtc
    48901 tgagcaagtg gccttgaatc aacaggaggc acaagctcgt ttggctgctt tggaggataa
    48961 gagaaattca ctcagcaaag aaaagtctga taaagaaagc tctttagctc tgttagaggg
    49021 aaatctagtc caaaataatc aaaaactcaa tcgtttagaa gctgaattgc tggctttctc
    49081 agacgatcct gatcagatga ttgagctctt acgtgaacgc tttgtagctc ttttacaaga
    49141 agaagcggat gtctcaaacc agttgacccg tattgagaat gagttggaaa atagtcgtca
    49201 gctttctcaa aaacaagcag atcaactaga aaagctgaaa gagcaattag ctatagctaa
    49261 agagaaggct agtcagcaaa aggaagagct tgaaactgcc aaggagcagg ttcagaaatt
    49321 attggctgac taccaagcta ttgccaagga gcaagaggag cagaaaactt cctatcaagc
    49381 tcaacaaagc caactctttg accgtctgga taatctcaaa aacaagcagg ccagagctca
    49441 aagtttggaa aatatcctga gaaatcatag taacttttat gcaggtgtta agagtgttct
    49501 ccaagaaaaa gatcgcctag gtgggattat tggtgcagtc agtgagcatc tgacctttga
    49561 tatgcattat caaactgccc tagaaattgc gcttggagcg agtagccaac atatcatcgt
    49621 agaagatgaa gagtcggcaa ccaaggctat tgacttcctt aaacggaaca gagccggtcg
    49681 tgcaaccttt cttcctttga ccactatcaa ggcgcgtacg atttctagtc agaaccaaga
    49741 tgctatcact gtaagcccag gtttccttgg gatggcagat gagttggtga cttttgatac
    49801 tagactggaa gccattttca agaacttgct agctacgacg gctatctttg atgccgtaga
    49861 acatgcgcgt gcagcagctc gccaagttcg ttatcaggtt cgtatggtga cattggatgg
    49921 gacagaatta cgcacgggtg gttcctatgc gggtggtgcc aatcgccaaa ataacagtat
    49981 tttcatcaag ccagaactgg agcaattaca aaaagaaatt gctgcagatg aagcaagctt
    50041 gcgttcagaa gaagcggctt tgaagacctt acaagaccag atggctacat tgacagaaag
    50101 attagaagtc atcaaatctc aaggagaaca ggcacgtatt caggagcaag gcttgtccct
    50161 cgcttatcag caaactagtc agcaagttga agaactggaa actctttgga aactccaaga
    50221 agaggaaata gatcgtcttt ccgagggaga ttggcaagcg gataaggaaa aatgccaaga
    50281 tcgtcttgct gcaatcgcca gtgacaagca aaatctggaa gctgagattg aagagattaa
    50341 gtctaacaaa aatgccatcc aagaacgcta tcaaaacttg caggaagagc tagcgcaagc
    50401 tcgtttgctt aagacagaac tgcaagggca aaaacgttat gaagttgctg atattgaacg
    50461 cttaggcaag gaattggaca atcttgattt tgaacaagag gaaatccagc gccttcttca
    50521 agaaaaggtt gataatcttg agaaggttga tacagaattg ctcagtcaac aggcggaaga
    50581 agccaaaact cagaaaacaa atctccaaca aggtttgatt cgcaagcagt ttgagttgga
    50641 tgatattgaa ggtcaactgg atgatattgc tagtcatttg gatcaggctc gccaacagaa
    50701 tgaagagtgg attcgcaagc aaacacgtgc tgaagccaag aaagaaaagg tcagcgagcg
    50761 cttgcgctat ttacaaagtc aattaacaga ccaatatcag attagctata ctgaagctct
    50821 agaaaaggcg catgaattgg aaaacctcaa tctggcagag caagaggtgc aggatttaga
    50881 gaaagctatt cgctcactgg ggcctgtcaa tatagaagct attgaccagt acgaagaagt
    50941 tcacaatcgt ctggatttcc taaatagcca acgagatgat attttgtcag cgaaaaatct
    51001 gctccttgag accattacag agatgaatga tgaggtcaaa gatcgcttta aatcaacctt
    51061 tgaggccatt cgtgaatcct ttaaagtgac cttcaaacag atgtttggag gaggtcaggc
    51121 agacttaatc ttgactgagg gagacttgtt gacagctggg gttgagattt ctgttcaacc
    51181 tccaggtaag aaaatccagt cgcttaacct catgagtggt ggtgaaaaag ccttatcagc
    51241 tcttgctttg cttttttcta tcattcgagt taagactatc ccatttgtca tcttggatga
    51301 ggtagaggcc gcgctggacg aagccaatgt taaacgtttt ggggattacc tcaatcgatt
    51361 tgacaaggac agccagttta tcgtcgtaac ccaccgtaag ggaaccatgg cagcggctga
    51421 ttctatctat ggagtgacca tgcaagaatc gggggtctca aaaattgttt cggttaagtt
    51481 aaaagattta gaaagtattg aaggatgaca attaaactag tagcaacgga tatggacgga
    51541 accttcctag atgggaatgg acgctttgat atggatcgtc tcaagtctct cttggcttcc
    51601 tacaaggaaa aagggattta ctttgcggtg gcttcgggtc ggggatttct gtctctggaa
    51661 aaattatttg ctggtgttcg tgatgacatt attttcatcg cggaaaatgg cagtttggta
    51721 gagtatcaag gtcaggactt gtatgaagcg actatgtctc gtgactttta tctggcaact
    51781 tttgaaaagc tgaaaacgtc accttatgta gatatcaata aactgctctt gacgggtaag
    51841 aagggttcat atgttctaga tacggttgat gagacctatt tgaaagtgag tcagcattat
    51901 aatgaaaata tccaaaaagt agcgagtttg gaagatatca cagatgacat tttcaaattt
    51961 acaaccaact tcacagaaga aacgctggaa gctggagaaa cttgggtaaa cgataatgtc
    52021 cctggtgtca aggctatgac aactggcttt gaatctattg atattgttct ggactatgtc
    52081 gataagggag tggctattgt tgaattagct aaaaaacttg gtatcacaat ggatcaggtc
    52141 atggcttttg gagacaatct taatgactta catatgatgc aggttgtggg acatcctgta
    52201 gctcctgaaa atgcacgacc tgaaatttta gaattagcaa agactgtgat tggtcaccat
    52261 aaggaccagt cggttatagc ttatatggag ggcttataat ggcagatata aaattaatcg
    52321 cattggactt ggatggtacc ttgctgacta ctgataaaag gctgacggat cgcaccaagg
    52381 caactttgaa agctgcgagt gatcgtggta tcaaggtcgt attgacaact ggtcgtccct
    52441 taaaagccat ggacttcttt ctccatgagt tagggactga cggccatgaa gatgagtata
    52501 ccattacttt taatggtgga ttagttcaga aaaatacagg agaaatcctt gataaaacag
    52561 tcttttcata tgatgatgtg gcacgtttgt atgaggaaac agagaaatta tcactgcctc
    52621 ttgatgccat ctcagaagga acagtttatc aaatccaatc ggaccaagaa agtctttatg
    52681 ccaaattcaa tccagctttg acttttgttc cagttgactt tgaagacctg tctagtcaaa
    52741 tgacctacaa caaatgcgtg actgcctttg ctcaagaacc cttggatgca gccattcaga
    52801 agatttctcc agaattgttt gaccaatatg aaatctttaa atcacgtgaa atgttgctag
    52861 aatggtcacc aaagaatgtt cataaagcaa caggtttggc aaaactaatt agccatcttg
    52921 gaattgatca aagtcaagtg atggcctgtg gtgacgaggc caatgacctc tctatgattg
    52981 aatgggcagg gctcggtgtt gccatgcaaa acgctgttcc tgaagtaaag gcagccgcaa
    53041 atgtagtgac gccgatgacc aacgatgagg aagctgtcgc ctgggctatc gaagaatatg
    53101 tgctaaagga gaactaagat atgggattat ttgaccgtct attcggaaaa aaagaagaac
    53161 ctaaaatcga agaagttgta aaagaagctc tggaaaatct tgatttgtct gaagatgttg
    53221 atcctacctt cacagaagtt gaagaagttt ctcaagaaga agctgtgctt gaagaaagtc
    53281 aggattcaga gccagctgta ggggtttctc aagaagaaat agaagaatta ccagaggaag
    53341 agaagcttga gcacgaagga actatagaag aaaataattc tgaagttctt gaagcagaaa
    53401 ggcctcaaac agaagaaact gttcaggaaa aatatgaccg cagtcttaag aaaactcgca
    53461 caggtttcgg tgcccgcttg aatgccttct ttgctaactt ccgctctgtt gacgaagaat
    53521 ttttcgagga actggaagaa ctgttgatta tgagtgatgt tggtgtccaa gtcgcttcta
    53581 acttaacgga ggaactacgt tacgaagcca agcttgaaaa tgccaagaaa cctgatgcac
    53641 ttcgtcgtgt catcattgag aaattggttg agctttatga aaaggatggt agctacgatg
    53701 aaagcatcca cttccaagat aacttgacag ttatgctctt tgttggtgtg aatggtgttg
    53761 ggaaaacaac ttctatcgga aaactagccc accgctacaa acgagctggt aagaaggtca
    53821 tgctggttgc agcagatacc ttccgtgcgg gtgcagtagc tcagctagct gaatggggcc
    53881 gacgagtaga tgttccagta gtaactggac ctgaaaaagc tgatccagcc agcgtggtct
    53941 ttgatggtat ggaacgtgcc gtggctgaag gtatcgatat tctcatgatt gatactgctg
    54001 gtcgtctgca aaataaggat aaccttatga ctgagttgga aaagattggt cgtattatca
    54061 aacgtgttgt gccagaagca ccacatgaaa ccttcttggc acttgatgca tcaacaggtc
    54121 aaaatgccct agtacaggcc aaagaatttt cgaaaatcac acctttaacg ggaattgttt
    54181 tgactaagat tgatggaact gctcgaggag gtgtggttct agccattcgt gaagaactca
    54241 atattcctgt aaaattgatt ggttttggtg aaaaaatcga tgatattgga gagtttaact
    54301 cagaaaactt catgaaaggt ctcttggaag gtttaatcta atcagaagca aaaatcctgc
    54361 aaggcataaa cttgcaggaa atttttttat tcgaaacgac catcttgacg ataggcgata
    54421 tctggttgcc aagtccattt ggcaccgaat ttttcaagta ggtcaaagct ggcttgaggt
    54481 cccatgcttc cagctttata gtcatgaagt ggggcaccat tttcagccca gagctcttca
    54541 atacggtcaa tcaacttcca tgatgcacca acttcatccc agtggctaaa gttagttgag
    54601 ttgttattta ggacatcata aatcaatttc tcgtatggtt ctggagaagc accagttgca
    54661 gtcgcatctg tacggtaatc aagtgagtta ggagccaagt taaattcttc tcctacttgc
    54721 ttcccattta ggctaagaga gaagccttct gttggttgaa tatagatggt caaaatattt
    54781 ggagcaagtg gttctccaaa gatagaatcc atttgtttaa agacgatgtt gacatgagtt
    54841 cctttttcag tcagtcgttt acctgtacgg aaaaagaaag gaacactacg gaatcgatcg
    54901 ctgtctacaa agaaggcacc agatgtaaag gtttcagttg ttgattctgg attcacattt
    54961 ggctcgctac gataagagat gtatttcatg ccatcaatct taccagagcg gtattgccca
    55021 cggataaagt gttctttgag ttcttcatca gttggatgat agaggttttt aaagacctta
    55081 atcttttcag cacgaatctc gtcttttgtg aagattgctg gtttgtccat ggcgaggagc
    55141 gaaagaagtt gtagagtgtg gttttggacc atgtcacgga gggcaccgga ttggtcatag
    55201 tagccaccac gttcttctac acccaagcgc tccgcaaagg taatttgaac attgtcgata
    55261 aaatccttgt tccaaacgtt ttcaaaaatc aagtttgcaa agcgaactgc aaagatgctt
    55321 tggatcattt ccttaccaag ataatggtcg atacggaaaa tttgttcttc gtcaaatgtt
    55381 gctaggagtt cgtcattcaa cttgcttgca gttgcgtaat ctgtaccaaa tggtttttca
    55441 acgatcaagc gctcaaaacc tttgccatcg acaatgtttt cagatttgag gtgtttggca
    55501 atggttccaa agaactgagg tgccatagac aagaagaaga gcttattgtg ttcagcttgg
    55561 tatttttcat taagctcagc ttgtaattga cgcaaagcaa tataatgttc cgaatcattg
    55621 acatcatggc tttgatagta gaagtggcta gcaaattctt gggcttgctc ggtactatct
    55681 gccaaatcaa ggatggactc gacaactaca gattcaaaat attccttact ccaaggtcta
    55741 cgggcagttc caataacggc aaagtgcttg gaaagattgc cggattgata tagtctaaaa
    55801 agggaagggt agagcttgcg tttagccagg tctccactcg caccgaaaat tgtaacaata
    55861 accttagatg acatctagct acctaatttc tatttttatt cctagtcttg ctaggtatga
    55921 ggaaacctca tttcataaac ttaattctaa cataattttc cgaaaaatca aaaattccaa
    55981 tacgaggtag aaaaactgca aggaaatcct tacagtttga gtttagacgt ttaagacctt
    56041 atctaagaac tctttcagac gagggtgttg tgggttatca aagatttggt caggtgttcc
    56101 gtcttcaagg aactcgccat ctgcagtaaa gataacgcgg ttggcaacct gacgagcaaa
    56161 tcccatctca tgggttacga taatcatggt catgccttgc tcagccaatt ccttcataac
    56221 gttaagtacg tctccaacca tctcagggtc aagggcagaa gttggttcat cgaagagcat
    56281 gatgtctgga ttcattgcta ggccacgagc gatggccaca cgttgttttt gaccacctga
    56341 taggttatct ggattggcat tagctttatc tgctagtcca accttttcaa gcaactccat
    56401 tcccaattcc tcagcttctt ccttagtcat caacttgtgc tcaataggag caaaggtgat
    56461 gttgtccaat acagacatat gagggaagag gttgaagtgt tggaatacca tgccgatatt
    56521 ttcacggacg tggtcaacat tggttgtttt ttcagttaaa tcatagccgt tcacagtgat
    56581 gtgaccgcta gtgacttctt ctaaaagatt gaggctacgg aggaaagttg acttaccaga
    56641 acctgaagga ccgatgatac aaacaacatc tccttcatag aacttagtcg taattccttt
    56701 taggacttca ttttttccat agtgcttgtg taaatcattt acatcaattt ttaattttgc
    56761 cattaacgaa tcctcttttc taagcgtttc gctagtctag tcaaaagtgt gataattaca
    56821 agatagaaga tagcaaggat tgcatacatc ttgaaacttt ggtagttacg agcaatgata
    56881 atcttaccag tttggaagag ttcaaccaaa ccgatagcag atacgatagt tgtatcttta
    56941 agagcgataa cgaattggtt gacaaagttt ggcaacatca atttagttgc ttgtggcaag
    57001 ataatcttac gcatggtttt tccataagag atacccaagc ttcggctggc ttccatttgg
    57061 ccaactggaa cggcctgaat accaccacga acgatttcag cgatataagc agccgcattg
    57121 agtgagaggg caatggttcc agctacaaag tcgttaattg ggctttgttg gcctgtgata
    57181 gactcgatga agtttggaat tccccagaag atgaaggctg caagaatcat caatggaata
    57241 ccacgaataa cgtcaacgaa aatctcagag atgacgcgaa gagatttgta tgggctaacg
    57301 ctaaacatac cgaagataat tccgatgaca atggcaatag caaatgagat aagagctaga
    57361 gcaagagtga taccaagacc gctaaggagt tgtttgtagt tgttttgaag caagccccag
    57421 agcgttgttt cgtcaacagt acttgttgaa gcagttgaag attcgctagc taggtatttg
    57481 tcaagaatct tttggaattc accgtttgct ttaaggtttg caagtccgtt gttgaacatt
    57541 tcaatcagtt ctggatttgc tcctttttta acggcaaagg ctgtttcacc gattggagtt
    57601 ccagagattg gagttttcaa tttttgacct tggctgatag aatatttgag aacaggttca
    57661 tcatccataa cggcatcaat ggcaccagtg tttaaactgt catacattga agaaccatca
    57721 gcaaaggttt tgattttgta accgtatttg ctttgatttt ctgttaggaa ggtttgagaa
    57781 gcagttccgt ttttaacacc gactgtcttt ccttttagat cttcataaga agcaatattg
    57841 cttgattctt tgacaccaag aatggtatta gcagtgtagt atgattctga gaagtcaaaa
    57901 gttgccttac gagcatctgt gacagacata ccagcaatga taccatcggc ttgaccagct
    57961 tggacagcac tgatagcagc atcaaaacca gggttggtga tttcaatttc aaaaccttgg
    58021 tctttagcga ttgccttaat caattccata tcaataccag tgtattggtt gcttgaattt
    58081 tggaaaacaa aaggtgcaaa agaagaatcg ctggcaatga tatatttagc cttaacagga
    58141 atagctttta atcctgcgag agtagttgta gttggcactg ctgaagatga tgaagcagtc
    58201 catttcttga taattttatc aagactacca tcttttttca tttcagccaa ggcttggtta
    58261 aattcagtaa ccaggtgctc gtatttactt ccttttttca caccgaaagc aaaacttcct
    58321 acagcttcac catccatttc aatatggagg tcttgacctt ggttaatggc atattcgata
    58381 acaggtttgt catccatcat ggcatcgatg gcaccagcac tcaagctgtt gttcattaaa
    58441 tcaccagtgt caaatgtttt aatagtaaag ccgtatttat ctttgattgt ttcaaggaaa
    58501 cgttgagcgg cagttccgtt tttaacacca acggttttgc cagttaattg gtcgtacttg
    58561 ctaattttgt gtgactttgt agtagcaatg acaacttttg tatcatagta agtatcagac
    58621 atggtgaaga ctttttcacg ttctttagtc tttgtcatcc ctgccatgat agcgtcggct
    58681 tgcccagctt gaaccgcatt gactgctgcg tcaaatccag gataggacat ctgaatgttc
    58741 cagcctttaa tctcagcgac tttgttaata atgtcaacat caattccttt ataagtttga
    58801 tctgaatctt taaactcaaa aggtgcatag gcggtatcag aaacaatctt aatcgtttct
    58861 gctttggcaa tacctaatga gaaaattggg aataaaatta gcaaaaatgc tagaaatttt
    58921 ttcttcattt ttagtctcct tttccgaata ttctctcatt atatcagaaa aagtaaaaaa
    58981 aggcaaattt ttatattttt cgtgtcagaa aatataacat tgatttttcc ttttctttct
    59041 tgaattgcta ttaaaaattg ctataataat actatatata gaagaaaaga ggacggggat
    59101 atgaagaaca aaagaatatt taaagacttc caagcttcaa aaatgaattt aaacctttac
    59161 acaagcccct tgttagcctt tgtttttgtc ttcataggag agtttgtggc ttatacttta
    59221 tatggtatta gtttgttagc tctcatcgga cttgctagaa attttggaga ggctggtcaa
    59281 aatcttgcaa gctacttgca gaccttgcat cagagcttga cggataaaac aagtgacttt
    59341 cgtttaattt taggattact ggcctttggt tttattctta acactgtgtt cagatggaca
    59401 agaaaagttg agaaaagacc tattcgaacc ttgggatttt atagagagaa ttgcctcagc
    59461 aatcttctga aaggatttag tctaggcctg gcactttttc ttctgacctt gttaagttta
    59521 gtggtcttag gtcaatatcg tttggaatcc attcacttga atccttatta tcttgccttt
    59581 gtcgtcttta ctatcccatt ttggatttta caggggacag cagaagaagt ggtggcccgt
    59641 gcttggctac ttcctcaatt ggcctcaaga accaatctaa aactagctat tcttatatct
    59701 agcctgttct ttaccctgct tcatatgggc aattctggcc tcacccctct atctctagta
    59761 aatctctttt tattcggagt tgccatggct ctttaccttc tcaaaactga tacagtttgg
    59821 ggtgttgcag gtattcatgg tgcttggaat tttgctcagg gtaatctctt tgggatttta
    59881 gttagtggtc aaccgtcagg aacgtctctg atgacctttt taccacaagg caatcaagat
    59941 tggctatcag gtggttcttt tggcatagaa ggttccatta tgacaagtct ggtattacta
    60001 ctgctgattg tctatcttgc taataaatta aagaaagaaa atgaaaggat gtgacttcgg
    60061 tccgtccttt tcttcgtgaa aatactataa gtatgctaaa ataggaatag cacatggaga
    60121 gaggattctt atgatcaatc acattacaga taatcaattt aaactagtat caaaatatca
    60181 accatcagga gatcaacccc aagctatcga gcagttggtg gataacattg aggggggaga
    60241 aaaagctcag attctgatgg gggcgactgg aacagggaag acctatacta tgagtcaggt
    60301 catttctaaa gtcaataaac caactctggt tattgcccac aataaaactc tggctggtca
    60361 gctctatggg gagtttaagg aatttttccc tgaaaatgca gttgagtatt tcgtatccta
    60421 ctatgattat taccagccag aggcctatgt cccttctagc gatacctata ttgagaagga
    60481 tagttctgtc aatgacgaga ttgacaagct tcgccactca gctacctcag cccttttgga
    60541 gcgtaatgat gttattgtcg tggcctcagt ctcttgtatc tatggtttgg gttcgcccaa
    60601 ggaatacgct gatagtgtcg ttagtctccg tcctggtcta gagatttctc gtgataaact
    60661 cttgaatgac ttggtcgata ttcagtttga acgcaatgat attgatttcc aacgcggaag
    60721 atttcgcgtt cgtggggatg tggtagagat tttcccagct tcccgagatg aacatgcctt
    60781 tcgagtagaa ttttttggag acgaaattga ccgtattcgt gaagttgagg ctctgacagg
    60841 tcaggtgttg ggagaagtgg atcatttagc gattttccca gcgacacact ttgtgaccaa
    60901 tgacgaccac atggaagttg ccattgcaaa gattcaggcc gagttggaag aacaattagc
    60961 tgtctttgaa aaggaaggta aactgcttga agcccagcgt ttgaaacagc ggacagagta
    61021 tgatatcgaa atgttgcgtg agatgggcta taccaatggg gttgaaaatt attctcgcca
    61081 catggatgga cggagcgaag gagagcctcc ttatacgctt ctcgacttct tcccagatga
    61141 tttcttgatt atgattgacg agagtcatat gaccataggg caaatcaagg gcatgtacaa
    61201 tggagaccgt tcgcgtaaag aaatgctggt taattatggt ttccgtttgc cgtctgcttt
    61261 ggacaatcgt cctctccgtc gggaggagtt tgagagtcac gttcatcaga ttgtttacgt
    61321 ttcagcgaca cctggtgact atgaaaatga acagaccgag acagtgattg agcaaatcat
    61381 tcgtccaacg ggactcttgg atccagaggt ggaagtccgt ccgactatgg gacagattga
    61441 tgacctcttg ggtgaaatca atgcccgcgt tgaaaaaaat gagcgtacct ttatcacaac
    61501 tttgaccaag aaaatggcag aggacttgac cgactacttc aaggaaatgg gtatcaaggt
    61561 taagtacatg cactcggata tcaagacctt ggaacggacg gagattatcc gtgacctgcg
    61621 cttgggtgtc tttgatgtct tggtcggaat taacctgctc cgtgaaggaa ttgacgttcc
    61681 tgaagtgagc ctcgtagcta ttctcgatgc tgacaaggaa ggtttccttc gcaacgaacg
    61741 tggactcatc cagactattg gacgtgctgc tcgtaacagt gaaggccatg tcatcatgta
    61801 tgcagacacg gttacccagt ctatgcaacg tgctatcgat gaaactgccc gccgtcggaa
    61861 aattcagatg gcctataatg aagagcatgg tatcgtacca cagacaatca agaaagaaat
    61921 ccgtgacctg attgctgtga ccaaggcagt tgctaaggaa gaggacaagg aagtcgacat
    61981 caatagcctc aacaaacaag agcgcaaaga actcgtcaag aaactagaaa aacaaatgca
    62041 agaagccgtc gaagtacttg actttgaact ggcggctcag atccgtgata tgatgttgga
    62101 agtcaaggcc ttggattagg ggaatagtat gatttattta agaaagttaa agagagaaga
    62161 tttgatgtct ttatgggaaa tggcttattc acaacttaat ccagtttgga aacagtatga
    62221 tgctccctat tatgatgatt atcagtattt ttcaaatttt aaagaattcg aactacaaaa
    62281 atcagaatcc attttaagca actcaaatcg ccttggtatt tttgttgatg ataaactagt
    62341 tgggactgtt tcgcgttatt gggtatgtaa acaaacaaga tggatggaat tgggaattgg
    62401 tatttatgat aaaaaattct ggaacactgg tattgggaaa gttgctatgt tgcagtggat
    62461 agataggacg tttcaggatt acttggagtt ggagcatctg ggtttgacaa cttggtcagg
    62521 gaatcttggt atgatgaaac ttgctgaaaa attaagaatg aaaaaagaag ctcatattcc
    62581 aaaagttcgt tattatcaag gtaaatattt tgatagtatt aaatatggta ttttgagaga
    62641 agactgggag aaaacaaatg acggttatta tcaaatcaat ggaaactcct gaagagatag
    62701 aaggtaagcc ccttgttcac tggcaaacgt ggagagaggc ttatgatggc cttttgcctg
    62761 cagaatttca ggagacaatg acattagaaa gatgtcgatt ctttagtcaa aagtatccag
    62821 aaaatacatt gattgcgatg gatggtatga aggtagttgg ttttatcagt tatggcaact
    62881 ttcgtgatga gactattcaa gctggcgaaa ttattgcttt atatgtttta aaagactatt
    62941 atggaaaagg tatcgcacaa aagttaataa aagcagcttt gattgctctt aatcattttt
    63001 ctgaaatttt cttatgggta ttgaaagata ataagcgcgc aattgctttc tatcaaaaaa
    63061 tgggctttac ttttgatgaa caagaaaaga tacttgaact tggaaagccc ataaaggaaa
    63121 aacggatggt attctattct aaataatttt aaaaagtaga agctaatggt actggtatca
    63181 agtctaaaaa tttaataaat tagaaagtga gtaaatttat gtctcgagca caattaacga
    63241 ttttaacaaa tatttgtctg attgaagatc tcgaagctca gcgcgtggtg atgcagtatc
    63301 gcgctcctga aactaatcgc tggtctggtt atgcctttcc aggaggccat gtagaaaatg
    63361 gcgaatcttt cgcagagtct gtcattcgtg aaatctatga agaaacaggg ttgactatcc
    63421 aaaatcctca acttgtcggc attaaaaatt ggccactaga tacaggtggg cgctatattg
    63481 tcgtttgtta taaggcaact gagttctctg gtacccttcg ctcttcagat gaaggagaag
    63541 tttcttgggt gcaaaaagac cagattccaa acttggatct ggcctatgat atgctacctt
    63601 tgatggagat gatggaagca tcggacaaat ctgaattttt ctaccctcgc cgtacagaag
    63661 acgattggga aaagaaaatt ttctaatcct ttactaaata acctagctga tccaaggcct
    63721 cctcgatata gtggaggtct tgttgtgttt cggcttcgac taggtggtaa tggacaccat
    63781 ctgtcaattc agataaaggt ttaaaatcag aatgctcgac ttgttctaga aaatgttgaa
    63841 cgtctcggcg gcaagacagt ttaagcaagg tttcaatttc tccataaacg ggatggtcaa
    63901 tcaaagtatt ctggacatgc ccaccattat cgacaatagc aaggagttcc tgaccgattt
    63961 cttcaacttc atgtttcact ttgaaaagtt tgtgaacata aggattggta tcaatttgct
    64021 tatagatgta gccacgattg gtggatagga taggagcgcc atcggctctc aaaattgcaa
    64081 tgtcctgcac aatgacctga cgtgtgacat gaaaatgttc cgccaaactt tggccattaa
    64141 gggctttagg agcttctttc aagagttgga gcagggcttg tttgcgatct tttgtcatag
    64201 cttttccttt taacggcgtt ttcgaagcac tttatagaca gctagtgcta atgtatagtc
    64261 taccatacta tggataattg tgccaaatcc aactagtaca aatagaacat agaacatgtt
    64321 ttctacattg gtacccgaag ttgcgtaaaa aaggacacag gctaatactt cagcaagggc
    64381 atgaacaaca gccaaaacaa aattgaaaac ccaggaagat tttggtttat ctagggtatc
    64441 ggggaatttt tgtaggtaaa gagatcctaa agcaccaaaa gatatatggg aaaaagcccg
    64501 aaaaactata accatgggat agccagccat caaaaatcca aaactagagg ctaggatgac
    64561 aaaaactgcc atcaagggcg acaagaacat ggctataaaa atagcgatgt ggctccccaa
    64621 agtataggaa gcaggtggaa tgacaatctt gaaaggcata acaattggaa tcaaaatcgc
    64681 aatagccgtt aaaagggctg tcattgtcat aaattgtgtc tttttccgtg tattcacaag
    64741 aatctccttt ttaactgcat atacactagt atggtacaat aaaccagaca ataaagcaag
    64801 aatttacttg ggtttataga tcatttttta gttaaaagtt atagtagatg gaaactagaa
    64861 tagtccacct ctacttctaa aacattgtta gcgatttgac tgtcctgatc gatttgtcct
    64921 gttcttattt cgttttacta tagtaaagat ttcattaaaa agaaactgta tagagcaaaa
    64981 tctccacctt caggtttgaa agcggagatt gtttttattt tttcaaggtt tgtagtcgtg
    65041 gaacaatggc tagggttaga attgcagaaa tgaccaattc agcaattgaa tttgttgaga
    65101 taacggttgc cagaagaagt tggatatttc cattataaac atttccaaat aggaagaaga
    65161 ttcctccaag gacaaagata gtatttgtca aggaaccaag ggctccagct aaaatcagac
    65221 cagtcttgtt tttcatcagt ttatagacta agtaaggagt taaaccaatc aaaatacgtg
    65281 ggacgatggc aatgatagct gagtagatgt ttccgtttgg tacgaaggga gagaagaggt
    65341 agcttgtcgg tagaatcgta atcgtgttaa ccgtcaagct aagtaatccc atcaaaaatc
    65401 caagtgtaac cccaactcgt ggaccataaa taatgctggc aataatgaca ggaatatgaa
    65461 caatggtcgg tttgattgga aatggaaaaa ggttaaagat aagtgagctc agaaagtgta
    65521 tcacgagcat ggtagcaaaa aagatagcaa tgggtgcaat attagagcgt tttttcatcg
    65581 atagtttcct ttattctttc taaaataatt gtgaggtcag ctaaagctcc tcgtccgtgg
    65641 tctccacaag ctagtaggga ttccttagga gcaatcagct gatagccgta ggtttctaat
    65701 gttttcagat tattctgagt tactggatgg tcatacattt ttgtattcat agcaggagct
    65761 attagtttgg gaatatgact tggtagggct agagctgtac tggttaccat gttgtccgca
    65821 aatccgtgag ctagttttgc aatagtgtta gcagttgcag gtaccacgat aaataaatct
    65881 gctttttttc caagttcgat atgattgacc tgatcaggat agggttcctt catgacatcc
    65941 aagtggacag gattctgtga gagtacctgt agtgtcaaag gttggataaa ctctgtagca
    66001 gcctgagtca ttaagacagt gacttgatgg ccttgttttt ttagagaact gactaaatct
    66061 gccgacttat aagaggcgat tgaacccgtt acagccaaga gaatgtttgc catagttttc
    66121 ctttctaaga atgataggct tgaatttttt caaggaggag ttctgcaatt tcttctttag
    66181 tctggactgt ttgaagctga tttttctcaa caaatatagc tcggtgctga tctgctgaaa
    66241 tttgagtcag gtcattcgcg atgattaaat ctgcttgatt cttgataaga ctttttcgtg
    66301 caatgtcaac cagatgatct tcggtaacat caaccagcag tttgaaacca atcagatgaa
    66361 tagtgggatt ccattccttg actagggata tgattttggg tgtcttttta aggaacaaaa
    66421 cctgaacctc atcagttgaa gaaatcttgg cctgatgatt ctgcttgctt aaaaattctt
    66481 ttagattgga gctagcctga acttcctcaa gccctgtcat ataaacagga gtgtagtcag
    66541 aaacagccat tgagtggatc aagacctgat aatcctgaac acgttcttgc atttctatta
    66601 gaaggtcctt ggtattggta atttctcgaa tacttaggtt aggatgaggc tctggcttca
    66661 gagctcgttt tgtcgtaatt aaacaaactt catgccctgc agaaagcaaa gtctctgtga
    66721 taattttccc caagtgacct gtagaatggt tagtgataga gcggacgcta tcgatagctt
    66781 cactggtacc gcccgatgta actaaaattt tcatagcact attgtacaca aaaataagcg
    66841 gtaagtaaaa tgaaagtgat aaatttttgg taaaaacgaa gatttactat agtttcaaac
    66901 tataaagcca tataaaattt aagaaaggac tctaaaagcc ttaaaaacag agatatttac
    66961 gaacgtttag agagttttag gatgttaaaa atcttgtttt gtgatataat gaattatcat
    67021 ataagaggtt agaggaattt tgaatgaaaa cagatattga aatcgcacag agtattgagt
    67081 tgaagccaat tgttgatgtt gtagagaaac ttggtatttc ttatgacgat ttggagttgt
    67141 acggaaagta caaggctaaa ctcagctttg ataaaattcg tgcagttgag agcaatccag
    67201 tcggtaaatt gatcttggtt actgccatca acccaacacc tgcaggtgaa ggaaagtcga
    67261 cgcttaccat tggtcttgcg gatgccttga acaagattgg caagaaaacc atgattgcta
    67321 tccgcgaacc gtctcttggt ccagtcatgg ggatcaaggg tggtgctgct ggtggtgggt
    67381 atgcacaagt tctgccaatg gaagacatca acctccactt tactggagat atgcatgcta
    67441 ttacaactgc caacaatgcc ctttctgcct tgattgacaa ccacttgcac caagggaatg
    67501 agctggaaat tgatcaacgt cgtatcctct ggaaacgcgt tgtggacttg aacgaccgtg
    67561 cgctccgcca tgtgactgtt ggtcttggtg gtcctctaaa cggtattcca cgtgaggatg
    67621 gttttgatat tacagttgct tcagaaatca tggcaattct ttgcttggca acggacatcg
    67681 aggacttgaa acgtcgtttg gcgaatatcg ttattggtta tcgctatgac cgtacgcctg
    67741 tttctgtagg tgatttgcag gttgagggtg ccttggcttt gattttgaag gatgctatta
    67801 agccaaactt ggttcagaca atttacggta cacctgcctt tgtacacggt ggtccatttg
    67861 ccaatatcgc tcatggctgt aactctgttt tggcgacgac aacagccctt cacttggctg
    67921 attacactgt tactgaagct ggttttggtg cggaccttgg tgctgagaaa ttccttgata
    67981 tcaagacacc aaacttgcca acatctccag atgcagttgt cattgtcgca acccttcgtg
    68041 cccttaagat gaatggtggt gtggctaaag acgctctgac tgaagaaaat gtagaggcag
    68101 ttcgtgcagg ttttgctaac ttgaaacgcc acgttgaaaa tatccgtaag ttcggtattc
    68161 cagcagttgt agctattaac gaatttgtat ctgatacaga agctgaaatt gcagtcttaa
    68221 aagaactctg tgcctcaatc gatgtaccag ttgaattggc tagtgtctgg gctgatggag
    68281 cagaaggtgg agtagcactt gccgaaacag ttgttaagac aattgctgaa aatccagcta
    68341 actataaacg tttgtacgat aatgcccttt ctgtccaaga aaagattgaa aaaattgtca
    68401 ctgaaatcta tcgtggtagc aaagtgaact ttgagaagaa agctcaaaca caaattgctc
    68461 aaatcgttca aaacggttgg gacaaattgc caatctgtat ggctaaaact caatacagtt
    68521 tctcagacaa tccaaatgcg cttggagcac cagaaaactt tgaaattacc attcgtgaat
    68581 tggtaccaaa attaggtgca ggcttcatcg ttgccttaac tggtgatgtt atgaccatgc
    68641 caggtcttcc aaaacgtcca gcagctctca acatggatgt tgaaagcgat ggaactgtac
    68701 taggcttgtt ctagtggatt gaaattgact ttaagtgagt ttggaaataa tatccaagct
    68761 cattttttct cagactgcaa gcagttcatc aataagattt atactcttcg aaaatctctt
    68821 caaactacgt cagcttcacc ttgccgtagg tatatgatac tgactc
//
LOCUS       DAVBEO010000005        64162 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 009
            SAMEA1678075-rid20185393.denovo.005, whole genome shotgun sequence.
ACCESSION   DAVBEO010000005 DAVBEO010000000
VERSION     DAVBEO010000005.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678075
            Sequence Read Archive: ERR226392
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 64162)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 64162)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980207.1
            Genome Coverage       :: 150x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:50:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 72 of 147
            Pseudo Genes (incomplete)         :: 72 of 147
            Pseudo Genes (internal stop)      :: 42 of 147
            Pseudo Genes (multiple problems)  :: 32 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..64162
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678075-rid20185393.denovo.005"
                     /strain="KS 009"
                     /db_xref="taxon:1313"
     gene            complement(138..485)
                     /locus_tag="VQ543_000346"
     CDS             complement(138..485)
                     /locus_tag="VQ543_000346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003017645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HET2611137.1"
                     /translation="MNLNQLDIIVSNVPQVCADLEHILDKKADYADDGFAQFTIGSHC
                     LMLSQNHLVPLENFQSGIIIHIEVEDVDQNYKRLNELGIKVLHGPTVTDWGTESLLVQ
                     GPAGLVLDFYRMK"
     gene            complement(596..2371)
                     /gene="spxB"
                     /locus_tag="VQ543_000347"
     CDS             complement(596..2371)
                     /gene="spxB"
                     /locus_tag="VQ543_000347"
                     /EC_number="1.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000191798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate oxidase"
                     /protein_id="HET2611138.1"
                     /translation="MTQGKITASAAMLNVLKTWGVDTIYGIPSGTLSSLMDALAEDKD
                     IRFLQVRHEETGALAAVMQAKFGGSIGVAVGSGGPGATHLINGVYDAAMDNTPFLAIL
                     GSRPVNELNMDAFQELNQNPMYNGIAVYNKRVAYAEQLPKVIDEACRAAISKKGPAVV
                     EIPVNFGFQEIDENSYYGSGSYERSFIAPALNEVEIDKAVEILNNAERPVIYAGFGGV
                     KAGEVITELSRKIKAPIITTGKNFEAFEWNYEGLTGSAYRVGWKPANEVVFEADTVLF
                     LGSNFPFAEVYEAFKNTEKFIQVDIDPYKLGKRHALDASILGDAGQAAKAILDKVNPV
                     ESTPWWRANVKNNQNWRDYMNKLEGKTEGELQLYQVYNAINKHADQDAIYSIDVGNTT
                     QTSTRHLHMTPKNMWRTSPLFATMGIALPGGIAAKKDNPDRQVWNIMGDGAFNMCYPD
                     VITNVQYDLPVINLVFSNAEYGFIKNKYEDTNKHLFGVDFTNADYAKIAEAQGAVGFT
                     VDRIEDIDAVVAEAVKLNKEGKTVVIDARITQHRPLPVEVLELDPKLHSEEAIKAFKE
                     KYEAEELVPFRLFLEEEGLQSRAIK"
     gene            complement(2578..4821)
                     /locus_tag="VQ543_000348"
     CDS             complement(2578..4821)
                     /locus_tag="VQ543_000348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HET2611139.1"
                     /translation="MTEIVKASLENGIQKIRIRAEKGYHPAHIQLQKGIPAEITFHRA
                     TPSNCYKEILFEEEGILEPIGVDEEKVIRFTPQELGRHEFSCGMKMQKGSYIVVEKTR
                     KSLSLLQRFWITSIFTVPLVILMIGMLTGSISHQVMHWGTFLATTPIMLVAGKPYIQS
                     AWASFKKHNANMDTLVALGTLVAYFYSLVALFAGLPVYFESAGFILFFVLLGAVFEEK
                     MRKNTSQAVEKLLDLQAKTAEVLSDDSYVQVPLEQVKVGDLIRVRPGEKIAVDGVVVE
                     GVSSIDESMVTGESLPVDKTVGDTVIGSTINHSGTLVFRAEKVGSETVLAQIVDFVKK
                     AQTSRAPIQDLTDKISGIFVPVVVILGIMTFWVWFVLLRDSVVVLGASFVSSLLYGVA
                     VLIIACPCALGLATPTALMVGTGRSAKMGVLLKNGTVLQEIQKVQTLVFDKTGTLTEG
                     KPVVTDIIGDEVEVFGLAASLEDASQHPLAEAIVKRASEAGLEFQTVENFQSLHGKGV
                     SGRINGKQVLLGNAKMLDGMDISNTYQDKLEELEKEAKTVVFLAVDNEIKGLLALQDI
                     PKENAKLAISQLKKRGLRTVMLTGDNAGVARAIADQIGIEEVIAGVLPEEKAHEIHKL
                     QQSGKVAFVGDGINDAPALSVADVGIAMGAGTDIAIESADLVLTTNNLLGVVRAFDMS
                     KKTFHRILLNLFWAFIYNVVGIPIAAGVFSGVGLALNPELAGLAMAFSSVSVLTSSLL
                     LNFSKID"
     gene            complement(4831..5202)
                     /locus_tag="VQ543_000349"
     CDS             complement(4831..5202)
                     /locus_tag="VQ543_000349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000932058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupredoxin domain-containing protein"
                     /protein_id="HET2611140.1"
                     /translation="MLNSIVTIICIALIAFILFWFFKKPEKSGQKAQQKNGYQEIRVE
                     VMGGYTPELIVLKKSVPARIVFDRKDPSPCLDQIVFPDFGVHANLPMGEEYVVEITPE
                     QVGEFGFACGMNMMHGKMIVE"
     gene            complement(5213..5608)
                     /locus_tag="VQ543_000350"
     CDS             complement(5213..5608)
                     /locus_tag="VQ543_000350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopY/TcrY family copper transport repressor"
                     /protein_id="HET2611141.1"
                     /translation="MQISDAEWQVMKIIWMQGEQTSTDLIRVLAERFDWSKSTIQTLL
                     ARLVEKECLTRKKEGKSFVYSALLTLDQSRDLLVQDIKDKVCSRRIRNLLADLIVECE
                     FTQTDLEDLEAVISEKKSSAVTEVRCNCM"
     regulatory      5792..5890
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            5974..6765
                     /gene="thiD"
                     /locus_tag="VQ543_000351"
     CDS             5974..6765
                     /gene="thiD"
                     /locus_tag="VQ543_000351"
                     /EC_number="2.7.1.49"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HET2611142.1"
                     /translation="MTYLPVALTIAGTDPSGGAGIMADLKSFQARDVYGMAVVTSLVA
                     QNTRGVQLIEHVSPQMLKAQLESVFSDIPPQAVKTGMLATTEIMEIIQPYLKKLDCPY
                     VLDPVMVATSGDALIDSSARDYLKTNLLPLATIITPNLPEAEEIVGFSIHDPEGMQRA
                     GRLILKEFGPQSVVIKGGHLKGGAKDFLFTKNEQFVWESPRIQTCHTHGTGCTFAAVI
                     TAELAKGKSLYQAVDKAKAFITKAIQDAPQLGHGSGPVNHTTFKD"
     gene            complement(6974..7606)
                     /locus_tag="VQ543_000352"
     CDS             complement(6974..7606)
                     /locus_tag="VQ543_000352"
                     /EC_number="2.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001078228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine phosphate synthase"
                     /protein_id="HET2611143.1"
                     /translation="MNREALRLYLVTNRYQDSVESFLAKVETACRSGVTIVQLREKNL
                     TTNQYYQLAKQVKEITDAYQVPLIIDDRLDVCLAVDAAGLHIGDDELPVSVARKVLGP
                     EKILGVTAKTVKRALEAEKSGADYLGTGAIFPTTTKENAPITLISTLKTICQTVAIPV
                     VAIGGLTSENIDQLMGTGIAGVAVVRDLMQAEDIEAKTQAFLTKLHDILS"
     gene            complement(7599..8402)
                     /locus_tag="VQ543_000353"
     CDS             complement(7599..8402)
                     /locus_tag="VQ543_000353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyethylthiazole kinase"
                     /protein_id="HET2611144.1"
                     /translation="MQALTNPFPIGSSSLIHCMTNEISCEMLANGILALGCKPVMADD
                     PREVLDFTKQSQALFINLGHLSAEKEKAIRMAASYANQSSLPMVVDAVGVTTSSIRKS
                     LVKDLLDYRPTVLKGNMSEIRSLVGLKHHGVGVDASAKDQETEDLLQVLKDWCQTYPG
                     MSFLVTGPKDLIVSENQVAVLENGCTELDWITGTGDLVGALTAVFLSQGKTGFEASCL
                     AVSYLNIAAEKIVVQGMGLEEFRYQVLNQLSLLRRDENWLDTIKGEVYE"
     gene            complement(8402..8926)
                     /gene="thiW"
                     /locus_tag="VQ543_000354"
     CDS             complement(8402..8926)
                     /gene="thiW"
                     /locus_tag="VQ543_000354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001225563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy coupling factor transporter S component
                     ThiW"
                     /protein_id="HET2611145.1"
                     /translation="MRKHQLQVHKLTILSMMIALDVVLTPIFRIEGMAPMSSVVNILA
                     GIMMGPVYALAMATVTAFIRMTTQGIPPLALTGATFGALLAGLFYKYGRKFYFSALGE
                     IVGTGIIGSIVSYPVMVLFTGSAAKLSWFIYTPRFFGATLIGTAISFIAFRFLIKQEF
                     FKKVQGYFFAERID"
     gene            complement(8931..9623)
                     /gene="tenA"
                     /locus_tag="VQ543_000355"
     CDS             complement(8931..9623)
                     /gene="tenA"
                     /locus_tag="VQ543_000355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiaminase II"
                     /protein_id="HET2611146.1"
                     /translation="MEFTDIAMELSKKAWQASFHHPFILQLQEGNLEPAIFRYYLIQD
                     AYYLKAFSEIYHLLADKTSNQEMKRLLKQNAQGLVEGELFIRQQFFKELEINDQEMEQ
                     HPIAPTCYHYISHIYRQFAEPNLAIAFASLLPCPWLYHDIGKSLNLKPSPNPLYQQWI
                     ETYITDELEQQIREEGALVNQLYRESDETDKQKMLDAFHISVHMEAKFWEMAYQHQTW
                     KSDLQSLEKGEE"
     gene            complement(9634..10284)
                     /locus_tag="VQ543_000356"
     CDS             complement(9634..10284)
                     /locus_tag="VQ543_000356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt ABC transporter permease"
                     /protein_id="HET2611147.1"
                     /translation="MVKVATQTPIISLFLLILSLETSFIPSIALNLSVVAFCILFMLY
                     YRRFKMLAWMIILAIFPSFANYWAVQLHGDASQAVMLGTRAFVTVCIGLVFVSSISLK
                     ELLLYLAQKGLSRSWSYALIVVFNSFPLIQQEIKSLKEACLLRGQKLHFWSPLIYSKV
                     LMTVFRWRHLYLRALSAYGYDEHAQLKNSYRTFYIPKKTKLIYLLFFLLLQTSLFL"
     gene            complement(10286..11671)
                     /locus_tag="VQ543_000357"
     CDS             complement(10286..11671)
                     /locus_tag="VQ543_000357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000522086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2611148.1"
                     /translation="MGLELRAIQSPIFSEPFDFTFHAQAFTLLVGSSGSGKSSLFQMI
                     AQVSSLPYSGQVLIDGSEVSQLSIVERVQTVGILLQNPNHQFTMESLFEELVFTMENI
                     GYHLQEIDSKIAEVVQQCRCKDILHRLIHHLSGGEKQKAALAVLFAMNPRVYLLDEPF
                     ASIDRKSRIEILEILKELVYDGKTVILCDHDLSDYKAYIDHMVELRDGKLREVFQIPS
                     YEMTQVASKEVASSPELFHMNRVTGELGNRPLFSIADFTFYQGISCILGDNGVGKSTL
                     FRSILQFQKYKGSITWKGSVLKKKKSLYRDLTGVVQEAEKQFIRVSLREELQLDGPDS
                     ERNQRIFQALRYFDLEQAVDKSPYQLSGGQQKILQLLTILTSKASVILLDEPFAGLDD
                     RACHYFCKWIVEERNQGRSFLLISHRLDPLISVVDYWIEMTSQGLRHVKEVTITKPLT
                     SQSSNTQGEVR"
     gene            complement(11672..12232)
                     /locus_tag="VQ543_000358"
     CDS             complement(11672..12232)
                     /locus_tag="VQ543_000358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000915269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HET2611149.1"
                     /translation="MLKKWQLKDVILLAFLSIFFGGVFVGSGYVYNILSLLLTPLGLQ
                     AFANEILFGLWCMAAPIAAIFVPRVGSATIGEVLAALAEVLYGSQFGLGALLSGFVQG
                     LGSEFGFIVTKNRYESWLSLTANSIGITLVSFVYEYIKLGYYAFSLPFVLSLLVVRFI
                     SVYFFCTILVRAIVKLYHQFATGGKA"
     regulatory      complement(12494..12582)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            complement(12791..13420)
                     /locus_tag="VQ543_000359"
     CDS             complement(12791..13420)
                     /locus_tag="VQ543_000359"
                     /EC_number="2.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000468574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine phosphate synthase"
                     /protein_id="HET2611150.1"
                     /translation="MFHKELLKLYFICGTTTCQGKNLYTVVEEALKGGITLFQFREKG
                     EGALEGLEKLELAIQIKELCKKYNVPFIVNDDIDLAMEIDADGVHVGQDDIGVDEIRK
                     LMPDKIIGLSIRNEEEFQQSKVEYVDYVGVGPVFGTQSKDDAGGTIGYEGLELMRKLL
                     PQMPLVAIGGIQTKHIKDIIKTNMDGVSIISAISYAKNIEKTVREMSEQ"
     gene            complement(13422..14204)
                     /gene="thiM"
                     /locus_tag="VQ543_000360"
     CDS             complement(13422..14204)
                     /gene="thiM"
                     /locus_tag="VQ543_000360"
                     /EC_number="2.7.1.50"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000202454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyethylthiazole kinase"
                     /protein_id="HET2611151.1"
                     /translation="MTSLKLLKEKAPLVICITNDVVKNFTANGLVALGASPAMSEFPA
                     DLEDLLKYAGGLLINIGTLTDENWKLYQAALKIAEKYNVPAVLDPVACGAGEYRKKVA
                     DDLINNYKLAAIRGNAGEIASLVGIDVASKGVDSAGVDNIDEIALAANEKFNIPIVVT
                     GEVDAIAVNGEVVMIHNGSAMMPKVIGTGCLLGAVVASFIGLEKGQELKSLETAMLVY
                     NIAGEMAEKRPNGHLPGTFKVEFINALYEITDEDVKEFKRVK"
     gene            complement(14447..15115)
                     /locus_tag="VQ543_000361"
     CDS             complement(14447..15115)
                     /locus_tag="VQ543_000361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000449895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TenA family protein"
                     /protein_id="HET2611152.1"
                     /translation="METQDYAFQPGLTVGELLKSSQKDWQAAINHRFVKELFAGTIEN
                     KVLKDYLIQDYHFFDAFLSMLGACVAHADKLESKLRFAKQLGFLEADEDGYFQKAFKE
                     LKVAENDYLEVTLHPVTKAFQDLMYSAVASSDYAHLLVMLVIAEGLYLDWGSKDLALP
                     EVYIHSEWINLHRGPFFAEWVQFLVDELNRVDKNREDLTELQQRWNQAVALELAFFDI
                     GYDV"
     regulatory      complement(15330..15418)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            complement(15672..16808)
                     /gene="lctO"
                     /locus_tag="VQ543_000362"
     CDS             complement(15672..16808)
                     /gene="lctO"
                     /locus_tag="VQ543_000362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate oxidase"
                     /protein_id="HET2611153.1"
                     /translation="MSYKTSNAEGHVDFINTYDLEPMAQQVIPKAAFGYIASGAEDTF
                     TLRENIRAFNHKLIVPHTLCDVENPSTEIEFAGEKLSSPIIMAPVAAHKLANEQGEVA
                     TARGVHEFGSLYTTSSYSTVDLPEISEALQGTPHWFQFYFSKDDGINRHIMDRVKAEG
                     YKAIVLTADATVGGNREVDKRNGFVFPVGMPIVEEYLPEGAGKSMDFVYKSAKQRLSP
                     RDVEFIAEYSGLPVYVKGPQCREDVERSLAAGASGIWVTNHGGRQIDGGPAAFDSLQE
                     VAEAVDRRVPIVFDSGVRRGQHVFKALASGADLVAIGRPVIYGLALGGSVGVRQVFEH
                     LNAELKTVMQLSGAQTIEDVKHFKLRHNPYNPTFPVDPRDLKLY"
     gene            complement(17433..18923)
                     /gene="lysS"
                     /locus_tag="VQ543_000363"
     CDS             complement(17433..18923)
                     /gene="lysS"
                     /locus_tag="VQ543_000363"
                     /EC_number="6.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003055423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine--tRNA ligase"
                     /protein_id="HET2611154.1"
                     /translation="MSTEHMEELNDQQIVRREKMAALREQGIDPFGKRFERTANSQEL
                     KDKYANLDKEQLHDKNETATIAGRLITKRGKGKVGFAHLQDREGQIQIYVRKDAVGEE
                     NYEIFKKADLGDFLGVEGEVMRTDMGELSIKATHITHLSKALRPLPEKFHGLTDVETI
                     YRKRYLDLISNRESFERFVTRSKIISEIRRYLDQKGFLEVETPVLHNEAGGAAARPFI
                     THHNAQNIDMVLRIATELHLKRLIVGGMERVYEIGRIFRNEGMDATHNPEFTSIEVYQ
                     AYADFQDIMDLTEGIIQHAAKSVKGDGPVNYQGTEIKINEPFKRVHMVDAIREITGVD
                     FWQDMTLEEAKTIAAEKKVPVEKHYTEVGHIINAFFEEFVEETLIQPTFVYGHPVAVS
                     PLAKKNPEDQRFTDRFELFIMTKEYGNAFTELNDPIDQLSRFEAQAKAKELGDDEATG
                     IDYDYIEALEYGMPPTGGLGIGIDRLCMLLTDTTTIRDVLLFPTMK"
     gene            complement(19051..19197)
                     /locus_tag="VQ543_000364"
     CDS             complement(19051..19197)
                     /locus_tag="VQ543_000364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactate oxidase"
                     /protein_id="HET2611155.1"
                     /translation="MSYKTSNAEGHVDFINTYDLEPMAQQVIPKAAFGYIASGAGDTF
                     TSFQ"
     gene            19423..20091
                     /locus_tag="VQ543_000365"
     CDS             19423..20091
                     /locus_tag="VQ543_000365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006531263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HET2611156.1"
                     /translation="MVEQYLPLYQKAFFLTLHIAVWGILGSFLLGLIVSIIRHYRILV
                     LAQVATAYIELSRNTPLLIQLFFLYFGLPRIGIVLSSEVCATLGLVFLGGSYMAESFR
                     SGLEAISQTQQEIGLAIGLTPLQVFYYVVLPQATAVALPSFSANVIFLIKETSVFSAV
                     ALADLMYVAKDLIGLYYETDIALAMLVVAYLIMLLPISLVFSWIERRLRHAGFGNPST
                     LSRK"
     gene            20051..20728
                     /locus_tag="VQ543_000366"
     CDS             20051..20728
                     /locus_tag="VQ543_000366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001154125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HET2611157.1"
                     /translation="MQDSGIQVLFQGNNLLRILQGLGVTIEISILSVLLSMMFGTVMG
                     IIMTSHSRIIRFLTRLYLDFTRIMPQLVLLFIVYFGLARNFNINISGETSAIIVFTLW
                     GAAEMGDLVRGAITSLPKHQFESGQALGLTNVQLYYHIIIPQVLRRLLPQAINLVTRM
                     IKTTSLVVLIGVVEVTKVGQQIIDSNRLTIPTASFWIYGTILVLYFAVCYPISKLSTH
                     LEKHWRN"
     gene            20729..21486
                     /locus_tag="VQ543_000367"
                     /pseudo
     CDS             20729..21486
                     /locus_tag="VQ543_000367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000401.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
     gene            21498..22359
                     /locus_tag="VQ543_000368"
                     /pseudo
     CDS             21498..22359
                     /locus_tag="VQ543_000368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000765255.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine ABC transporter substrate-binding
                     protein"
     gene            complement(22439..23086)
                     /locus_tag="VQ543_000369"
     CDS             complement(22439..23086)
                     /locus_tag="VQ543_000369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001002414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2611158.1"
                     /translation="MNEIIILKNIELKLKKTCVFQNLNFSCKQGEIIGITGANGSGKS
                     VLFKLIAGLYSPSYGEVLINGENIVPERKIPANLGALIEEPGFINYYSGFKNLQYLAS
                     IRGVVGNQEINDTLKIVGLYEQKDQKVKTYSLGMRKKLGIAQAIMENPSILLLDEPMN
                     ALDKSSVENMRTLFRKLSSEKGTTILIASHSEEDIRILCDKVYAIEDKVCTLCSD"
     gene            complement(23083..23781)
                     /locus_tag="VQ543_000370"
     CDS             complement(23083..23781)
                     /locus_tag="VQ543_000370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2611159.1"
                     /translation="MGKLSSHMWRLNKIIYTKYFWGYVLFWILICLGLWYWLEGNDRL
                     VIEILKGPNLSQNSFLVLSIWLLHWFIIHTFFLAVVYRRRASDFFMEVIRFSSIKLWI
                     RYQIWTCFLYGLILIMVKVLVIQFMLQLPNWDIGVLFIVDSLNACVLVLFCFMLYALG
                     ANVQMNFACVSFFLLMIVFGGLFVGNRTNYLFYILNRGNGDVGGDLFLQLLFLVFLFQ
                     SIFYFTRQKRRFIE"
     gene            complement(23791..24543)
                     /locus_tag="VQ543_000371"
     CDS             complement(23791..24543)
                     /locus_tag="VQ543_000371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2611160.1"
                     /translation="MKQFVQFYKKDFLSVLVYFILLLSCVLSSTVYLLRCRQYSIHPN
                     VLEWILVLLQDMTTGVYCFPFTYILFFFYLMNNYFNRLECRIRLKSIKHFTSFSFKLA
                     ALSTGIWTATLFLLIFLIAFSNGFSFSLEIKEVDFLREFYGISIANNASFFIGFFFSY
                     IAYYFFLSLLTISSFSWFKKSNMSLVFLFTFLFVESLFWIYQLNNGIIGLLPIFQYMV
                     NSNPYALIYWLTLLSIIIPLTVFSVHRNWRRV"
     gene            complement(24543..25307)
                     /locus_tag="VQ543_000372"
     CDS             complement(24543..25307)
                     /locus_tag="VQ543_000372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000394067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2611161.1"
                     /translation="MEFFICNLVRVVQSPRFYMSLFLTLLCMSLGNFLAFNGIYKIEG
                     LSIFFAASSIRGFSPISLVAALICTLPYSSQIIEDAESHFLTAQLCRISKKKYLAIVG
                     STAIISSFLVFFLPYLLLLGINLLVTPYQEIYIGDYSGALKELFDSNQLLYSLVTTLW
                     YGVWGAVFSIFGLASALLVKKKIGAIFIPVAYMMVGGIFWAILGLSYLEPVTTLALGY
                     QKDISLSLVSGHLAFILFVSCLVVYGTFFLHSEDYV"
     gene            complement(25403..25806)
                     /locus_tag="VQ543_000373"
                     /pseudo
     CDS             complement(25403..25806)
                     /locus_tag="VQ543_000373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000829085.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(25986..26618)
                     /locus_tag="VQ543_000374"
     CDS             complement(25986..26618)
                     /locus_tag="VQ543_000374"
                     /EC_number="2.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000170913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotate phosphoribosyltransferase"
                     /protein_id="HET2611162.1"
                     /translation="MTLAKDIASHLLKIQAVYLKPEEPFTWASGIKSPIYTDNRVTLA
                     YPETRTLIENGFVEAIKEAFPEVEVIAGTATAGIPHGAIIADKMDLPFAYIRSKPKDH
                     GAGNQIEGRVAQGQKMVVVEDLISTGGSVLEAVAAAKREGADVLGVVAIFSYQLPKAD
                     KNFADAGVKLVTLSNYRELIHLAQEEGYITPEGLDLLKRFKEDQENWQEG"
     gene            complement(26652..27353)
                     /gene="pyrF"
                     /locus_tag="VQ543_000375"
     CDS             complement(26652..27353)
                     /gene="pyrF"
                     /locus_tag="VQ543_000375"
                     /EC_number="4.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001206708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotidine-5'-phosphate decarboxylase"
                     /protein_id="HET2611163.1"
                     /translation="MREHRPIIALDFPSFEAVKEFLALFPAEESLYLKVGMELYYAAG
                     PEIVSYLKGLGHSVFLDLKLHDIPNTVKSAMKVLSQLGVDMTNVHAAGGVEMMKAARE
                     GLGSQAKLIAVTQLTSTSEAQMQEFQNIQTSLQESVIHYAKKTAEAGLDGVVCSAQEV
                     QVIKQATNPDFICLTPGIRPAGVAVGDQKRVMTPADAYQIGSDYIVVGRPITQAEDPV
                     AAYHAIKDEWTQNWN"
     gene            27674..27766
                     /locus_tag="VQ543_000376"
                     /pseudo
     CDS             27674..27766
                     /locus_tag="VQ543_000376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011516271.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            complement(28088..28801)
                     /locus_tag="VQ543_000377"
     CDS             complement(28088..28801)
                     /locus_tag="VQ543_000377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET2611164.1"
                     /translation="MLKRFLALVWLRCQIILSNKSILLQVLVPFAFTYFYKYLMETQG
                     KVNDQQALVLLMMCLPFSLALAVGSPITIILSEEKEKYNLQTLLLSGVKGSEYILSTM
                     FLPFLLTFVIMGTTPLILGVTIVHTFNYITIVLLTSLSIILFYLLIGLTAKSQVVAQV
                     ISLPAMILVAFLPMLSGLDKTVAKITDYSFMGLFTKFFTKWEGFSWNKTLIPNLTLLI
                     WIVLLLTLITITIRKKKIS"
     gene            complement(28794..29489)
                     /locus_tag="VQ543_000378"
     CDS             complement(28794..29489)
                     /locus_tag="VQ543_000378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000529917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2611165.1"
                     /translation="MTGQFLADKGQSIILGQKSQNLTSGELKRIGLVSDTSGFYEKMS
                     LYNNLLFYSKFYNISKSRVDNLLKRVGLYDSRKMVAGKLSTGMRQRMLLARALINKPA
                     VLFLDEPTSGLDPTTSRTIHELILELKTAGTTIFLTTHDMNEATLLCDYVALLNKGKL
                     VEQGAPSELIQRYNKDKKIKVTDYNGNQITFDFTSLEQVSQADLENIFSIHSCEPTLE
                     DIFITLTGGKLNA"
     gene            complement(29829..31161)
                     /locus_tag="VQ543_000379"
                     /pseudo
     CDS             complement(29829..31161)
                     /locus_tag="VQ543_000379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812020.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ThiF family adenylyltransferase"
     gene            complement(31145..31943)
                     /locus_tag="VQ543_000380"
                     /pseudo
     CDS             complement(31145..31943)
                     /locus_tag="VQ543_000380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001824573.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase M50 family protein"
     gene            complement(32733..33932)
                     /gene="divIB"
                     /locus_tag="VQ543_000381"
     CDS             complement(32733..33932)
                     /gene="divIB"
                     /locus_tag="VQ543_000381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000031166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein DivIB"
                     /protein_id="HET2611166.1"
                     /translation="MSKDKKNEDKEILEELKELSEWQKRNQEYLKKKAEEEAALAEEK
                     EKERQARMGEESEKSEDKQDQESETDQEDSESAKEESEEKVASSEADKEKEEKEEPES
                     KEKEEQDKKLSKKATKEKPAKAKIPGIHILRAFTILFPSLLLLIVSAYLLSPYATMKD
                     IRVEGTVQTTADDIRQASGIQDSDYTINLLLDKAKYEKQIKSNYWVESAQLVYQFPTK
                     FTIKVKEYDIVAYYISGENHYPILSSGQLETSSVSLNSLPETYLSVLFNDSEQIKVFV
                     SELAQISPELKAAIQKVELAPSKVTSDLIRLTMNDSDEVLVPLSEMSKKLPYYSKIKP
                     QLSEPSVVDMEAGIYSYTVADKLIMEAEEKAKQEAKEAEKKQEEEQKKQEEESNRNQT
                     TQRSSRR"
     gene            complement(33942..35000)
                     /locus_tag="VQ543_000382"
     CDS             complement(33942..35000)
                     /locus_tag="VQ543_000382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000724845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine--N-acetylmuramyl-
                     (pentapeptide) pyrophosphoryl-undecaprenol
                     N-acetylglucosamine transferase"
                     /protein_id="HET2611167.1"
                     /translation="MKKIVFTGGGTVGHVTLNLLLMPKFIEDGWEVHYIGDKRGIEHQ
                     EILKSGLDVTFHSIATGKLRRYFSWQNMLDVFKVCWGIVQSLFIMLRLRPQTLFSKGG
                     FVSVPPVIAARVSGVPVFIHESDLSMGLANKIAYKFATKMYSTFEQASSLSKVEHVGA
                     VAKVSDQKNPEPDELVDIQSHFNHKLPTVLFVGGSAGARVFNQLVTDHKKELTERYNI
                     INLTGDSSLNELSQNLFRVDYVTDLYQPLMELADIVVTRGGANTIFELLAIAKLHVIV
                     PLGREASRGDQLENAAYFVKKGYAEDLQESDLTLDSLEEKLSHLLSHKEDYQAKMKAS
                     KELKSLADFYQLLKKDLS"
     gene            complement(35002..36354)
                     /locus_tag="VQ543_000383"
     CDS             complement(35002..36354)
                     /locus_tag="VQ543_000383"
                     /EC_number="6.3.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000862950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanine--D-glutamate
                     ligase"
                     /protein_id="HET2611168.1"
                     /translation="MKVIDQFKNKKVLVLGLAKSGESAARLLDKLGAIVTVNDGKPFE
                     DNPAAQSLLEEGIKVITGGHPLELLDEEFALMVKNPGIPYNNPMIEKALAKGIPVLTE
                     VELAYLISEAPIIGITGSNGKTTTTTMIGEVLTAAGQHGLLSGNIGYPASQVAQIASD
                     KDTLVMELSSFQLMGVQEFHPEIAVITNLMPTHIDYHGSFSEYVAAKWNIQNKMTAAD
                     FLVLNFNQDLAKDLTSKTEATVVPFSTLEKVDGAYLEDGQLYFRGEVVMAANEIGVPG
                     SHNVENALATIAVAKLRGVDNQTIKETLSAFGGVKHRLQFVDDIKGVKFYNDSKSTNI
                     LATQKALSGFDNSKVVLIAGGLDRGNEFDELVPDITGLKKMVILGQSAERVKRAADKA
                     GVAYVEATDIADATRKAYELATQGDVVLLSPANASWDMYANFEVRGDLFIDTVAELKE
                     "
     gene            complement(36458..37099)
                     /locus_tag="VQ543_000384"
     CDS             complement(36458..37099)
                     /locus_tag="VQ543_000384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000571297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2611169.1"
                     /translation="MIELKNISKKFGSRQLFSDTNLHFEGGKIYALIGTSGCGKTTFL
                     NMIGRLEPYDKGQIIYDGTSLKDIKPSVFFRDYLGYLFQDFGLIESQTVKENLNLGLV
                     GKKLKEKEKISLMKQALNCVNLSYLDLKQPIFELSGGEAQRVALAKIILKDPPLILAD
                     EPTTSLDPKNSEELLSILESLKNPNRTIIIATHNPLIWEQVDQVIRVTDLSHR"
     gene            complement(37101..39122)
                     /locus_tag="VQ543_000385"
     CDS             complement(37101..39122)
                     /locus_tag="VQ543_000385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000732428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HET2611170.1"
                     /translation="MKKLFILLSTFFLSFFLAWIIVLRAPQYLYASYDSVSLLRVKKD
                     TQEPTREVFEQELENFANSEQSLIARRIVEPSKDGTTHFTYATYGQGTLPKEFQEASQ
                     ESRERSDPLNSYLLLSGSLTKEKLADKLGDLGYKASADRKIPPYFLAFRILLNPLILI
                     SLAIFGLSFFALVIITRIKEMRAAGIKLFSGQTLLSIMGHSLSTDIKWLLLSALLSFL
                     GGGVVLFSQGLFYPILLATYGFGISFYLLFLLAISILLMLLYLMSLSYKALVPVIKGR
                     LPLKRLMILTLLCQLVAVFTVGYAVKTGLMSYQRLKELEISKQAWQDRADYYQISFGL
                     GDRGKDTENQSKWYAFAKEAIEEEQALYVKDNLLHFANPQGKNEQGETLDTYSPDANT
                     LYVSPSYLDKEKVVVDAETKQKLAHLQKGEFILLLPEHLRSREAELKKVFEERLSYYG
                     KSGEEASAPLDYEMKAHVSYLSMGEKRFVYNNGENPVSTQYLTDPILVVFTPTSTGDS
                     FISLSSWSINAGKQLFIKGYESGLELLKKAGIYEQVSYLKEGRSVYLTRYNEVQTETA
                     TLILGAIVGIASSLLLFYSVNLLYFEQFRRDILIKRISGLRFFETHAQYMVSQFASFV
                     FGASLFILSSRDLVIGLLTLLVFLASAVLTLYRQAQKESRVSMTIMKGK"
     gene            complement(39193..39492)
                     /locus_tag="VQ543_000386"
     CDS             complement(39193..39492)
                     /locus_tag="VQ543_000386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
                     /protein_id="HET2611171.1"
                     /translation="MKTKKHRLLALALISSFTLLGAASAAVQYPDGGVWTYGEGSGGG
                     WAFSNYYHGKKYHYSSLVSRWNSHSDKGEASAGKTSYAWIWTKWGEQVAFYCDYD"
     gene            complement(39858..40112)
                     /locus_tag="VQ543_000387"
     CDS             complement(39858..40112)
                     /locus_tag="VQ543_000387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000262800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3165 family protein"
                     /protein_id="HET2611172.1"
                     /translation="MVYLVLGILLLLLYVFATPESIKGTVNIVAMVCILVALLILLVL
                     SFLKIFQLPTEIFLAIAMLILAYFSVRDITLMPVKKSKRR"
     gene            complement(40132..41973)
                     /gene="typA"
                     /locus_tag="VQ543_000388"
     CDS             complement(40132..41973)
                     /gene="typA"
                     /locus_tag="VQ543_000388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003078415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translational GTPase TypA"
                     /protein_id="HET2611173.1"
                     /translation="MTKLREDIRNIAIIAHVDHGKTTLVDELLKQSETLDARTELAER
                     AMDSNDIEKERGITILAKNTAVAYNGTRINIMDTPGHADFGGEVERIMKMVDGVVLVV
                     DAYEGTMPQTRFVLKKALEQDLVPIVVVNKIDKPSARPAEVVDEVLELFIELGADDDQ
                     LDFPVVYASAINGTSSLSDDPADQEATMAPIFDTIIDHIPAPVDNSDEPLQFQVSLLD
                     YNDFVGRIGIGRVFRGTVKVGDQVTLSKLDGTTKNFRVTKLFGFFGLERREIQEAKAG
                     DLIAVSGMEDIFVGETITPTDAVEALPILHIDEPTLQMTFLVNNSPFAGKEGKWVTSR
                     KVEERLQAELQTDVSLRVDPTDSPDKWTVSGRGELHLSILIETMRREGYELQVSRPEV
                     IVKEIDGVKCEPFERVQIDTPEEYQGSVIQSLSERKGEMLDMISTGNGQTRLVFLVPA
                     RGLIGYSTEFLSMTRGYGIMNHTFDQYLPLIPGEIGGRHRGALVSIDAGKATTYSIMS
                     IEERGTIFVNPGTEVYEGMIIGENSRENDLTVNITKAKQMTNVRSATKDQTAVIKTPR
                     ILTLEESLEFLNDDEYMEVTPESIRLRKQILNKAEREKANKKKKSAE"
     gene            42135..42860
                     /locus_tag="VQ543_000389"
     CDS             42135..42860
                     /locus_tag="VQ543_000389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001235004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA pseudouridine(516) synthase"
                     /protein_id="HET2611174.1"
                     /translation="MRLDNLLAQEKVSRKAMKQALLRGEILVDGCPARSLAQNIDTGL
                     QELLFQDRIIQGYEHTYLMLHKPAGVVTANKDKELPTVMDLLPSDIQSDKLYAVGRLD
                     RDTTGLLLLTDNGPLGFQLLHPQYHVDKTYQVQVNELLTPDHIQAFQKGIVFLDGTVC
                     KPAKLEILSASPSLSQASITISEGKFHQIKKMFLSVGVKVTSLKRIQFGDFTLNPDLA
                     ESNYRPLNQKELQIIKNYLEMSR"
     gene            complement(42900..43127)
                     /locus_tag="VQ543_000390"
     CDS             complement(42900..43127)
                     /locus_tag="VQ543_000390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000660075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2611175.1"
                     /translation="MKEKKKNPLFVGILSIILGLLFPIVGLILGIIGLVLAISYQKES
                     QLDYKIEKILNILGIVISVVNWIVAIALIFR"
     gene            complement(43216..43596)
                     /locus_tag="VQ543_000391"
     CDS             complement(43216..43596)
                     /locus_tag="VQ543_000391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HET2611176.1"
                     /translation="MVTWILWALILAMLAWMGFNYLRIRRAAKIVDNEEFEALIRTGQ
                     LIDLRDPAEFHRKHILGARNIPSSQLKTSLAALRKDKPVLLYENQRAQRVTNAALYLK
                     KQGFSEIYILSYGLDSWKGKVKTS"
     gene            complement(43596..43865)
                     /locus_tag="VQ543_000392"
     CDS             complement(43596..43865)
                     /locus_tag="VQ543_000392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000051789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqgQ family protein"
                     /protein_id="HET2611177.1"
                     /translation="MSLFLKKTQNFARMSLMKTFYDVQQFLKRFGIIVYMGKRLYDIE
                     LMKLELSRIYDAGLMDKLDYLEAEAVLRREHKVELDYIEKNGEKN"
     gene            43929..44837
                     /locus_tag="VQ543_000393"
     CDS             43929..44837
                     /locus_tag="VQ543_000393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HET2611178.1"
                     /translation="MRIQQLHYIIKIVETGSMNEAAKQLFITQPSLSNAVRDLENEMG
                     IEIFIRNPKGITLTRDGMEFLSYARQVVEQTQLLEERYKNPVAHRELFSVSSQHYAFV
                     VNAFVSLLKKSDMEKYELFLRETRTWEIIDDVKNFRSEVGVLFLNSYNRDVLTKMLDD
                     NHLLAHHLFTAQPHIFVSKTNPLAKKDKVKLSDLENFPYLSYDQGTHNSFYFSEEILS
                     QEHHKKSIVVSDRATLFNLLIGLDGYTIATGILNSNLNGDNIVSIPLDIDDPIELVYI
                     QHEKTSLSKMGERFIDYLLEEVQFDS"
     gene            complement(44891..45646)
                     /locus_tag="VQ543_000394"
     CDS             complement(44891..45646)
                     /locus_tag="VQ543_000394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001142149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HET2611179.1"
                     /translation="MPTILITGASGGLAQEMVKLLPNDQLILLGRNKEKLAQLYGNYS
                     HAELIEIDITDDSALEALVTDLYLRYGKIDVLINNAGYGIFEGFDQIADKDIHQMFEV
                     NTFALMNLSRHLAARMKESSKGHIINIVSMAGLIATGKSSLYSATKFAAIGFSNALRL
                     ELMPYGVYVTTVNPGPIRTGFFDQADPDGTYLKSVDRFLLEADAVAKKIVKIIGKNKR
                     ELNLPILLNLAHKFYTLFPKLADKLAGETFNYK"
     gene            complement(45667..46596)
                     /locus_tag="VQ543_000395"
     CDS             complement(45667..46596)
                     /locus_tag="VQ543_000395"
                     /EC_number="3.1.26.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000354350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Z"
                     /protein_id="HET2611180.1"
                     /translation="MDIQFLGTGAGQPSKARNVSSLALKLLDEINEVWLFDCGEGTQN
                     RILETTIRPRKVSKIFITHLHGDHIFGLPGFLSSRAFQANEEQTDLEIYGPQGIKSFV
                     LTSLRVSGSRLPYRIHFHEFDQDSLGKILETDKFTVYAEELDHTIFCVGYRVMQKDLE
                     GTLDAEKLKAAGVPFGPLFGKIKNGQDLVLEDGTEIKAADYISAPRPGKIITILGDTR
                     KTDASVRLAVNADVLVHESTYGKGDEKIARNHGHSTNMQAAQVAVEAGAKRLLLNHIS
                     ARFLSKDISKLKKDAATIFENVHVVKDLEEVEI"
     gene            complement(46611..47234)
                     /locus_tag="VQ543_000396"
     CDS             complement(46611..47234)
                     /locus_tag="VQ543_000396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine beta-lyase"
                     /protein_id="HET2611181.1"
                     /translation="MTDIKTLALKYGGYTSLDKVYLDQLLAGKTEQEQLTLITPPPSV
                     VNAYFAELYQKKSPQAATDYFAELSQELNLYNTEPSFTLENKPFIRLNLSGKSFGFCY
                     ESDGFGRIFSENEEKISDDLLFEIAQIFSHQLVFEESGKIYMKPVKDEEVVSLESLTA
                     LTDLERLADGRKRLKGYSQEDLLQEAAAFSGKRYFRSENRTAMLYID"
     gene            complement(47227..48465)
                     /gene="hflX"
                     /locus_tag="VQ543_000397"
     CDS             complement(47227..48465)
                     /gene="hflX"
                     /locus_tag="VQ543_000397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000573186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HET2611182.1"
                     /translation="MIETEKKEERVLLIGVELQGMDSFDLSMEELASLAKTAGAVVVD
                     SYRQKREKYDSKTFVGSGKLEEIALMVDAEEITTVIVNNRLTPRQNVNLEEVLGVKVI
                     DRMQLILDIFAMRARSHEGKLQVHLAQLKYLLPRLVGQGIMLSRQAGGIGSRGPGESQ
                     LELNRRSVRNQITDIERQLKVVEKNRATVREKRLESSTFKIGLIGYTNAGKSTIMNIL
                     TSKTQYEADELFATLDATTKSIHLGGNLQVTLTDTVGFIQDLPTELVSSFKSTLEESK
                     HVDLLVHVIDASNPYHEEHEKTVLSIMKDLDMEDIPHLTLYNKADLVEDFTPTQTPYT
                     LISAKSEDSRENLQALLLDKIKEIFEAFTLRVPFSKSYKIHDLESVAILEERDYQEDG
                     EVITGYISEKNKWRLEEFYD"
     gene            complement(48458..49342)
                     /gene="miaA"
                     /locus_tag="VQ543_000398"
     CDS             complement(48458..49342)
                     /gene="miaA"
                     /locus_tag="VQ543_000398"
                     /EC_number="2.5.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenosine(37)-N6)-dimethylallyltransferase
                     MiaA"
                     /protein_id="HET2611183.1"
                     /translation="MKTKIIVIVGPTAVGKTALAIEVAKCFNGEVVSGDSQQVYRGLD
                     IGTAKASPEEQAAVPHHLIDVREITESYSAFDFVSEAKMTIEDIHSRGKLAIIAGGTG
                     LYIQSLLEGYHLGGETPHEEILAYRASLEPYSDEELAHLVEQAGLEIPQFNRRRAMRA
                     LEIAHFGQDLENQEILYEPLIICLDDERSQLYERINHRVDLMFEAGLLDEAKWLFDHS
                     PNVQAAKGIGYKELFPYFRGEQTLEEARESLKQATRRFAKRQLTWFRNRMQVTFYQIG
                     ESGVQDRILSQIEEFLDD"
     gene            49463..49633
                     /locus_tag="VQ543_000399"
     CDS             49463..49633
                     /locus_tag="VQ543_000399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001051775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3042 family protein"
                     /protein_id="HET2611184.1"
                     /translation="MAKGFAKGLVTGVAGTVAAVAGAVYAFKKKVIEPEEQKAAFIEE
                     NRKKAARRRVSR"
     gene            complement(49681..50520)
                     /locus_tag="VQ543_000400"
     CDS             complement(49681..50520)
                     /locus_tag="VQ543_000400"
                     /EC_number="2.1.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003011065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HET2611185.1"
                     /translation="MTKADTIFKENIERILKEGVFSEQARPKYKDGTVANSKYVTGAF
                     SEYDLSKGEFPIITLRPIAIKSAIKEVLWIYQDQSNSLEVLNDKYNVHYWNDWEVGDT
                     GTIGERYGAVVKKHDIINKLLKQLETNPWNRRNIISLWDYQAFEETDGLLPCAFQTMF
                     DVRRVDGEIYLDATLTQRSNDMLVAHHINAMQYVALQMMIAKHFGWKVGKFFYFINNL
                     HIYDNQFEQAQELLRREPSNCQPRLVLNVPDGTNFFDIKAEDFELVDYDPVKPQLKFD
                     LAI"
     gene            complement(50617..51576)
                     /locus_tag="VQ543_000401"
     CDS             complement(50617..51576)
                     /locus_tag="VQ543_000401"
                     /EC_number="2.7.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002919069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family glucokinase"
                     /protein_id="HET2611186.1"
                     /translation="MSQKIIGIDLGGTSIKFAILTTAGEIQGKWSIKTNILDEGSHIV
                     DDMIESIQHRLDLLGLAAADFQGIGMGSPGVVDRDKGTVIGAYNLNWKTLQPIKQKIE
                     KALGIPFFIDNDANVAALGERWMGAGDNQPDVVFMTLGTGVGGGIVAEGKLLHGVAGA
                     AGELGHITVDFDQPISCTCGKKGCLETVASATGIVNLTRRYADEYEGDAALKRLIDNG
                     EEVTAKTVFDLAKEGDDLALIVYRNFSRYLGIACANIGSILNPSTIVIGGGVSAAGEF
                     LLQGVQKVYDENTFPQVRTSTKLALATLGNDAGVIGAASLVLQ"
     gene            complement(51703..52701)
                     /locus_tag="VQ543_000402"
     CDS             complement(51703..52701)
                     /locus_tag="VQ543_000402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
                     /protein_id="HET2611187.1"
                     /translation="MNKRLFLKMSLVTLPILALFSQPVLAEENIHFSSCKEAWANGYS
                     DLHEGEPGYSAKLDRDHDGVACELKNAPKGAFKAKQAATTQTDTTSSTASGWVKQDGS
                     WYYFDGNGNLVKNAWQGNYYLKADGKMAQSEWIYDSSYQAWYYLKSDGSYAKNAWQGA
                     YYLKSNGKMAQGEWVYDSSYQAWYYLKSDGSYARNAWQGNYYLKSDGKMAKGEWVYDA
                     TYQAWYYLTSDGSYAYSTWQGNYYLKSDGKMAVNEWVDGGRYYVGADGVWKEGQASTA
                     SSSNDSNSEYSAALGKAKSYNSLFHMSKKRMYRQLTSDFDKFSNDAAQYAIDHLDG"
     gene            complement(52751..53368)
                     /locus_tag="VQ543_000403"
     CDS             complement(52751..53368)
                     /locus_tag="VQ543_000403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000766583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HET2611188.1"
                     /translation="MKLIFLHGLGQSAESWKEVRNLLTDYPSEAIELFPSGVSNYQQA
                     KERVYQHLAQETEPFVLIGLSLGAALTLELSSYDLPNLRALILSGCPLKLAGNILFYL
                     QLLIFKLLPKRVFEKQGADKTLMVGVSEELKTLDLTDIAGTCSYPTLLICGSKDKPNL
                     SSMKALHRLLTDSQFQIIPDGPHVLNKAKPKEFVEKTRSFLELLK"
     gene            complement(53369..55090)
                     /gene="pabB"
                     /locus_tag="VQ543_000404"
     CDS             complement(53369..55090)
                     /gene="pabB"
                     /locus_tag="VQ543_000404"
                     /EC_number="2.6.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate synthase component I"
                     /protein_id="HET2611189.1"
                     /translation="MHRKTVIDFRTLGERYTFAQPIKELKTRNVEEVADLLAQVESYQ
                     EQGYYVVGYVSYEAAPAFEEKLAVHKDPLLGEYLLYFTVHDSVETSPIPLTYEDIDLP
                     SNWQEVTSAADYEKAIAQIHHHLRQGDTYQVNYTVQLKQKLSANPFAIYNRMVVEQEA
                     GYNAYVEHDEMAVISMSPELFFEQNDRELTTRPMKGTTQRGVTDQEDLEQASWLEQDP
                     KNRSENMMIVDLLRNDMNRISEVGSEHVERLCQVEQYSTVWQMTSTIKSQLREDVDLV
                     EIFRSLFPCGSITGAPKIATMEIIKDLEPQPRGVYCGTIGLLLPNGRRIFNVAIRTIQ
                     LHKGQAIYGVGGGITWDSTWESEYREVHQKAAVLYRKQARFQLITTGEISQKNLLFED
                     QHLERLRKASRYFAFPFDAEDLGHKIEEECQDCEANRDYRLRISLSKSGEIEVNRQVL
                     TPLSTSFCQAQVCLQEAALNQSFTYFKTTHRPHLSLGEQEKIYHNKSGELLETSIGNL
                     VLKIAGKLYTPPIRLGILPGIYRQYLLETGQVEEKVLTLADLTQAEAIYGCNAVRGLY
                     ELSLEEN"
     gene            complement(55159..60846)
                     /locus_tag="VQ543_000405"
     CDS             complement(55159..60846)
                     /locus_tag="VQ543_000405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000473008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HET2611190.1"
                     /translation="MFKKDRFSIRKIKGVVGSVFLGSLLMAPSVVDAATYHYVNKEII
                     SQEAKDLIQTGKPDRNEVVYGLVYQKDQLPQTGTEASVLTAFGLLTVGSLLLIYKRKK
                     IASVFLVGAMGLVVLPSAGAVDPVATLALASREGVVEMDGYRYVGYLSGDILKTLGLD
                     TVLEETSAKPGEVTVVEVETPQSTTNQEQARTENQVVETEETPKEEAPRTEESPKEEP
                     KSEVKPTDDTLPKVEEGKEDSAEPAPVEEVGGEVESKSEEKVAVKPESQPSDKPAEES
                     KVEPPVEQAKVPEQPVQPTQAEQPSTPKESSQEDNPKEDRGAEETPKQEESTPDTKAE
                     ETVEPKEETKTAKGTQEEDYVGEALVPEQLPEYKVTEGTLVEESTTELDYKTETTEDP
                     TKYTDEETVLRNGEKGSQVTKTTYKTIGGVKTDQVLSTSTEVTKEPVNQQVIRGTKPI
                     EGTTVETREEIIPFETKEQEDDTLKRGTRQVTQEGVNDKKQITETYKTIRGEKTSDAP
                     TITETVIEKPQDKIIKNGTKELEKPTLEWAKTDKDVLKKSATASYTLTKPAGVEIKSI
                     KVALKDNTGTVVKEVTVEENNLQATLDNLKYYQGYTLSTTMVYDRGNGEETEILEDKE
                     VQLDLKKVEIKDIKETRLMKVDENGNETDSSLLETVPENLTSYYLKITTNHNKVTRLA
                     ITNIEEVTEEETSLFKVTASAPDLIQRDSNNSLSQTYTYYIEKPKASQNNVYYNFKDL
                     VDAMQKNPNGEFKLGSDLNATNVPTPSKSYVTGKFTGHLTSVDGKHFSIHNTARPLFD
                     RVEGGSIKNINLINVNINMPWANQLASLAQTVKNATVENIKVTGTIVGNNNVAGILDK
                     LDDAGIMTNVAFIGKVQSVGDKGWNLAGIASEIYRGNLNKAYADVELKGLNTRAGAIV
                     GHLAHDFNPRDVGAWSNVRNSVAKGTIDVARGDVGGLIGKDWPWGTIDNNISLVNVKR
                     GDIFFGSNDMDDEFVSNWIKPNNATVIGVSSGDKTHKQSSKIKEISQVEADKKIKDMG
                     ITADTFEVTEHLVDKLNRRILRDEEYKTIQDYNANRELVYRNVEKLQPFYNKEWIVNQ
                     GNKLTTDSPLMNKEVLSVTAMKGNDFITDLTDADHIMVHYADKTKDIFTISPKDSQVK
                     QVKEYSVAELGEVVYTPNMVVKDRADLISAIEGILSPIELQSDPIYQRLGRTGDNRVN
                     AIKNLYLEESFKEVKDHLNTFVTKLVENEDHQLNTDEAAKRALIKKIEDNKAAVLLGL
                     TYLNRYYGVKFDNFNIKELMLFKPDFYGKNVSVLDRLIEIGSKEDYIKGSRTQESFRE
                     VVAKNTLSGNLHDFLTYNMKLFTNETDINVWFKKAIENNAYVVEQPSTNPAFANKKYR
                     LYEGLNNGQHGRMILSLLNLKDAHLFMISTYNTISFSSFEKYGKDTEEKRESFKSEIN
                     KRAKEQVNYLDFWSRLATDNVRDKLLKSQNVVPTPVWDNHGAPGGWPDRFGHRKDKPD
                     YAPIREFFGRIDKYHDYKYGYGAYAYIFADPQPMDAVYFVMSDLISEYGTSAFTHETT
                     HVNDRMAYLGGHRHRQGTDLEAFAQGMLQTPAEHGHQGEYGALGLNMAFERSNDGNQW
                     YNPDPTKLQTRDQIDHYMKNYNEAMMMLDYAEAEAVLPKVKGDNSKWFKKIDRETRRP
                     MDRNKLSGPHQWDKVRDLIDAEKTTNLETIDDLVNNNFMTIHGNPGNKVFHPEDFGTA
                     YVNVNMMAGIYGGNTSQGAPGSLSFKHNAFRMWGYYGYEHGFIDYVSSKHQGAANKEN
                     NGLLGDDFIIKKVSNNQFSNLEDWKKQWYGEVLTKSKKGFAPIEINGTQISTYEQLKT
                     MFDEAVTKDLTELNDSSIKDKYRNTVVLKSKVFKALLKNTDGFSGDLFTAPQA"
     gene            complement(60868..61431)
                     /locus_tag="VQ543_000406"
     CDS             complement(60868..61431)
                     /locus_tag="VQ543_000406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01440 family protein"
                     /protein_id="HET2611191.1"
                     /translation="MNETQIQRETRQVVEDVLEKTNLKQGVLFVLGLSSSEVLGGQIG
                     KESSQEIGELIVETILGILGSRGIHLAVQGCEHVNRALVVERQVAEQFDLEIVSVHPT
                     LHAGGSGQLAAFKFMQDPVEVEFIKAHAGLDIGDTAIGMHVKHVQVPIRPILREIGHA
                     HVTALASRPKLIGGARAHYPQDAIRKS"
     gene            complement(61547..63238)
                     /locus_tag="VQ543_000407"
     CDS             complement(61547..63238)
                     /locus_tag="VQ543_000407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HET2611192.1"
                     /translation="MKRSSLLVRMVISIFLVFLILLALVGTFYYQSSSSAIEATIEGN
                     SQTTISQTSHFIQSYIKKLETTSTGLTQQTDVLAYAENPSQDKVEGIRDLFLTILKSD
                     KDLKTVVLVTKSGQVISTDDSVQMKTSSDMMAEDWYQKAIHQGAMPVLTPARKSDSQW
                     VISVTQELVDAKGANLGVLRLDISYETLEAYLNQLQLGQQGFAFIINENHEFVYHPQH
                     TVYSSSSKMEAMKPYIETGQGYTPGHKSYVSQEKIAGTDWTVLGVSSLEKLDQVRSQL
                     LWTLLGASVTSLLVCLCLVWFSLKRWIAPLKDLRETMLEIASGAQNLRAKEVGAYELR
                     EVTRQFNAMLDQIDQLMVAIRSQEETTRQYQLQALSSQINPHFLYNTLDTIIWMAEFH
                     DSQRVVQVTKSLATYFRLALNQGKDLICLSDEINHVRQYLFIQKQRYGDKLEYEINEN
                     VAFDNLVLPKLVLQPLVENALYHGIKEKEGQGHIKLSVQKQDSGLVIRIEDDGVGFQD
                     AGDSSQSQLKRGGVGLQNVDQRLKLHFGANYQMKIDSRPQKGTKVEIYINRIETS"
     gene            complement(63235..63972)
                     /locus_tag="VQ543_000408"
     CDS             complement(63235..63972)
                     /locus_tag="VQ543_000408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET2611193.1"
                     /translation="MTYTILIVEDEYLVRQGLTKLVNVAAYDMEIIGQAENGRQAWEL
                     IQKQVPDIILTDINMPHLNGIQLASLVRETYPQVHLVFLTGYDDFDYALSAVKLGVDD
                     YLLKPFSRQDIEEMLGKIKQKLDKEEKEEQLQDLLTNRFEGNMAQKIQSHLADSQFSL
                     KSLASDLGFSPTYLSSLIKKELGLPFQDYLVRERVKQAKLLLLTTDLKIYEIAEKVGF
                     EDMNYFTQRFKQIAGVTPRQFKKGEDR"
BASE COUNT        19312 a        13919 c        11319 g        19612 t
ORIGIN      
        1 atgctttttg aaagcagatg agtattatat gcaatttctt tatataaaaa gaccggattg
       61 ctccgatctt tcaatagttc atattctcaa tttctatttt aaaaatagct aaggttaacg
      121 tcaaatgact acgcgaccta tttcatacga taaaaatcaa gcactagacc agcaggtcct
      181 tgaactaata aggactctgt tccccaatcg gttacagttg gtccgtgtaa aacctttata
      241 ccaagctcat tcaaccgttt gtagttctgg tctacatcct caacctcgat atgaataatg
      301 attcctgact gaaagttttc caaaggaacc aaatgatttt gtgacaacat aaggcagtga
      361 ctaccaatcg taaactgagc aaaaccatca tcagcataat ctgccttttt atccaaaata
      421 tgctccaagt cagcacagac ttggggaaca tttgaaacga taatatctaa ttgatttaaa
      481 ttcatttact ctcctccata aaaagaccga attgctccga tcttttaaag ttctgctcta
      541 tgaaaatcaa agaataaagt ctacaagttt catatttgat tttcggcgag aggaattatt
      601 taattgcgcg tgattgcaat ccttcttctt ccaagaagag acggaatggt acgagttctt
      661 ctgcttcgta tttttccttg aaggctttga tagcttcttc tgagtgaagt tttggatcca
      721 attcaagtac ttctactgga agtggacggt gttgagtgat gcgagcatcg atgacaacag
      781 ttttaccttc tttgttcaat ttaacagctt ctgcaacaac tgcatcgatg tcttcgatac
      841 ggtcaactgt gaatccaaca gctccttgag cttccgcaat tttagcgtag tcagcgtttg
      901 tgaagtctac accaaacaag tgtttgtttg tatcttcgta tttgttcttg atgaagccgt
      961 actcagcatt tgagaagaca aggttgataa ctggaaggtc gtattgaacg tttgtgataa
     1021 cgtctgggta gcacatgttg aatgctccat cacccatgat gttccatact tggcgatctg
     1081 gattgtcttt cttagcagcg ataccaccag gaagggcaat acccattgtc gcaaagagcg
     1141 gagatgtacg ccacatattc ttaggtgtca tgtgaaggtg acgagtagat gtttgagtag
     1201 tgttacctac gtcgattgag tagatagcgt cttgatcagc atgtttgttg attgcattgt
     1261 aaacttgata caattgcaat tcaccctcag ttttaccttc gagtttgttc atgtaatcac
     1321 gccagttttg gttgttctta acgtttgcac gccaccatgg agttgattca actgggttta
     1381 ctttgtcaag gatagcttta gctgcttgac cagcatcacc aaggattgaa gcgtcaaggg
     1441 catgacgttt accaagtttg taagggtcga tatcgacttg gatgaatttt tcagtgttct
     1501 tgaatgcttc gtaaacttca gcaaatggga agtttgaacc aaggaaaaga actgtgtctg
     1561 cttcaaagac cacttcgttg gctggtttcc aaccaacacg gtaagcagaa cctgtcaaac
     1621 cttcatagtt ccattcgaaa gcttcaaagt ttttaccagt tgtgatgatt ggtgctttga
     1681 ttttacgtga caattcagta atcacttcac cagctttaac accaccaaat ccagcataga
     1741 taactgggcg ttcagcattg ttcaagattt caacagcttt gtcgatttca acttcgttca
     1801 aagcaggagc gatgaatgag cgttcgtatg aacctgaacc gtagtatgag ttttcgtcga
     1861 tttcttggaa accgaagttt actggaattt caacaacagc tggacctttt ttagaaattg
     1921 cagcacggca ggcttcgtca attacttttg gcaattgctc agcgtaagct acacgtttgt
     1981 tgtaaacagc gataccgttg tacattgggt tttggttaag ctcttggaaa gcatccatgt
     2041 tcaattcgtt aactggacgt gatccaagga tcgctaggaa tggagtgtta tccatagctg
     2101 catcgtaaac accgttaatc aagtgagtcg cacctggacc acctgaacca actgcaaccc
     2161 cgattgagcc gccgaattta gcttgcataa ccgctgcaag agcacctgtc tcttcgtggc
     2221 gaacttgtaa gaagcggata tctttgtctt cagccaaagc gtccatcaat gagctgagtg
     2281 ttcctgatgg gataccgtag attgtatcta cgccccatgt tttcaatacg ttaagcattg
     2341 ctgcagatgc agtaattttc ccttgagtca taatgataac tctccttcaa tttttttaga
     2401 tttggagaat acgattacat agaattggaa acgttctcca aatttttact attccactgt
     2461 atcatattta tgctgacttt tctaaaaatc tgctcaaaac tctctattct ctattctaat
     2521 acagttttga aagttctgtc atttctgttt tataacaaag aaatctagtc attactttta
     2581 gtctatttta ctaaaattta acagaaggga actggtcaga acagatacag aactaaaggc
     2641 catggctaga cctgccaatt ctgggttgag agccagtcca acacctgaaa agactcctgc
     2701 tgcaatcgga attccgacaa cattgtagat aaaagcccag aaaagattga gtagaattcg
     2761 atgaaaggtt ttcttactca tatcaaaggc acgaaccact cctaaaagat tattggttgt
     2821 caacaccaaa tctgctgact cgatggcgat atctgttcca gctcccatag caatccccac
     2881 atctgctaca ctaagggcag gagcgtcatt gataccgtcc ccaacaaagg ctactttccc
     2941 tgactgttgc agtttatgga tttcatgggc tttttcttct ggcaagacgc ctgcaatgac
     3001 ctcttcaatt ccgatttgat ctgcaatagc acgcgccaca ccagcattgt ctcctgtcag
     3061 catgactgtt cggagaccac gtttttttag ctgactgatg gctagcttag cattttcctt
     3121 aggaatatct tgcaaagcaa gcaagccttt gatttcattg tcaacagcta agaacacaac
     3181 tgtcttagct tctttttcta gttcttctag tttatcttga taagtattag aaatatccat
     3241 accatccagc attttagcat ttccaagtaa aacttgtttt ccattgattc gccctgaaac
     3301 acctttcccg tgcaaggact gaaaattttc aacagtttga aactcaagtc cagcttcact
     3361 cgctcgctta acgatagcct cagccagtgg gtgttgagaa gcatcttcca aggaggctgc
     3421 caatccaaac acttctactt cgtcgccgat gatatctgtt accacaggtt tcccttccgt
     3481 caaagtcccg gtcttatcaa agacaagagt ttgaactttc tggatttcct gtaagacagt
     3541 tccatttttg aggagaaccc ccatcttggc actacgtcct gtccccacca taagggctgt
     3601 cggtgttgca agtcccaagg cacaaggaca ggcgataatc aaaaccgcca ctccgtagag
     3661 aagagaggac acaaagctag ctccaagcac gaccacacta tccctgagca agacgaacca
     3721 aacccaaaag gtcatgattc ctaaaatgac aactactggg acaaaaatcc ctgaaatctt
     3781 atccgtcaag tcctgaatcg gcgcacgact tgtctgagct ttcttcacaa aatccacaat
     3841 ctgagccaaa acagtctctg agccaacttt ttctgctcta aagacaagcg ttccactatg
     3901 attgatggtt gagccaatga cagtatctcc aactgtcttg tccacaggca gactctcacc
     3961 tgtcaccatg gattcgtcaa tactagagac accttctact acgacaccat caacagcaat
     4021 cttttcaccg ggacgcactc gaatcaggtc gcctaccttg acttgttcca aaggaacttg
     4081 gacataacta tcatcactca agacttctgc ggttttagct tgcaagtcca gtaatttctc
     4141 cacagcttgg gacgtatttt ttctcatttt ttcctcaaaa actgctccca aaagaacgaa
     4201 aaagaggata aatccagcac tttcgaagta aacagggaga ccagcaaaga gagcaactag
     4261 gctatagaaa taagccacta gagttcccag cgcaaccaag gtatccatgt tggcattgtg
     4321 ctttttaaaa ctggcccaag cactctggat atatggctta cctgcaacta acataatagg
     4381 cgttgttgct agaaaggttc cccaatgcat gacttgatga ctaatgctac ctgtcaacat
     4441 cccaatcatg agaatcacaa gaggcacagt aaagatacta gtaatccaaa aacgttgcag
     4501 gagagataga gattttcgag tcttctcaac gactatatag cttccctttt gcatcttcat
     4561 gccacaagaa aattcatgtc gccctaattc ttgaggtgta aaacgaatga ctttctcctc
     4621 atctacgccg attggttcca agataccttc ttcttcaaac agaatttcct tataacagtt
     4681 tgaaggagta gcacgatgaa aggtaatctc agctggaatt cccttttgaa gctggatatg
     4741 ggctggatga tagccttttt cagctcggat acggattttt tgaatgccat tttctaagct
     4801 tgctttcaca atttctgtca tagtctccac ctactctaca atcatcttgc cgtgcatcat
     4861 gttcatacca caagcaaagc caaactctcc aacctgctca ggcgtgattt ccactacata
     4921 ctcttccccc attggcaggt tcgcatgtac accaaaatct ggaaaaacaa tttgatccag
     4981 acatggtgaa ggatccttgc ggtcaaagac aatgcgtgct ggcactgatt tcttgaggac
     5041 aatcaactca ggagtatagc ctcccatgac ttccactcga atctcttggt atccgttttt
     5101 ttgctgggct ttttgtccag atttttcagg ctttttgaaa aaccaaaaca agataaacgc
     5161 gataagggca atacaaataa tggttacaat actatttaac atgacgtctc ctttacatac
     5221 aattacatct tacttctgtt acagcacttg atttcttctc tgaaatcaca gcttccaagt
     5281 cttccaagtc agtctgagta aattcacatt ctacaatcaa gtcagccaac aaattcctaa
     5341 tcctacggga acaaaccttg tctttgatat cttggacaag taaatcccga ctttggtcta
     5401 gagttaaaag ggctgaataa acaaaggact tgccttcttt tttccgagtc agacactctt
     5461 tctcaaccaa acgagccaaa agagtttgaa tggtcgactt ggaccagtcg aaccgctctg
     5521 ccaaaaccct aatcaaatct gtactggtct gctccccctg catccaaata atcttcatga
     5581 cctgccattc tgcatctgaa atctgcatta ccatacctcc aaaatctaca tttgtcaatt
     5641 acactcatca gtatactctt aaaatctaca tttgtcaatt atagaaataa tattttcttc
     5701 gaaaaataga attttaatca tttgaaaaac gatttgcagt caaatattac tatataaaca
     5761 ataaaaatat gctatactaa agaaaaaaga aaacaaccac taggggtgcg taaagctgag
     5821 attaacgact gttagatccc tctgactcaa tctaggtaat gctagctgat ggaagtggaa
     5881 atgataatgg ggactagcag tcttctattg cctttctaaa acagactagc ttgttcttaa
     5941 gaatacaaac ttcagttggt tgggaggttt tagatgactt atttacccgt tgctttgacc
     6001 attgcaggga ctgaccctag tggtggtgct ggcattatgg cagatttaaa gtcattccaa
     6061 gcgagagatg tctatggaat ggctgttgta accagtcttg tcgctcaaaa taccagaggt
     6121 gttcagctaa tcgagcacgt ttctcctcaa atgttgaaag cccaattgga gagtgtcttt
     6181 tctgatattc cacctcaggc tgtaaaaact ggaatgttgg ctactactga aatcatggaa
     6241 atcatccaac cctatcttaa aaaactggat tgtccctatg tccttgatcc tgttatggtt
     6301 gctacaagtg gagatgcctt gattgactca agtgctagag actatctcaa aacaaactta
     6361 ctacctctag caactattat tacgccaaat cttcctgaag cagaagagat tgttggtttt
     6421 tcaatccatg accccgaagg catgcagcgt gctggtcgcc tgattttaaa agaatttggt
     6481 cctcagtctg tggttatcaa aggcggacat ctcaaaggtg gtgctaaaga tttcctcttt
     6541 accaagaatg aacaatttgt ctgggaaagc ccacgaattc aaacctgtca cacccatggt
     6601 actggatgta cctttgctgc agtgattact gctgaactag ccaagggcaa gagtctttac
     6661 caggcagttg ataaggccaa ggcctttatc acaaaagcta ttcaagatgc ccctcaactc
     6721 ggtcatggtt ctggtccagt caaccataca acttttaaag attaagaaaa aaactctcta
     6781 gttcccactt taagggaatt agagagtttt tatactcttc gaaaatctct tcaaattacg
     6841 tcagcttcca tctgcaacct caaaacactg ttttgagctg acttcgtcag tcttatctaa
     6901 aacctcaagg cagtactttg agcaacctgc gactagcttt ctagtttact ctttgatttt
     6961 cattgagtat taattaggaa agaatgtcat gcaactttgt taaaaaggct tgcgtttttg
     7021 cctcaatatc ttctgcttgc atcaaatcac gtacaacagc tacaccagct atgccagtgc
     7081 ccataagctg atcaatattc tccgaagtca agcctccaat agcaactact ggaatggcaa
     7141 ccgtttggca aattgttttc aaggtcgata tcagagtaat gggcgcattt tccttggtgg
     7201 tggttgggaa aatggctcct gtacccaagt aatctgcacc tgatttctcc gcttccagag
     7261 ctcttttaac cgttttagcg gtgacaccga ggattttttc aggacccaag actttgcgag
     7321 ctaccgaaac tggtaattca tcatctccga tatgcagacc tgctgcatca accgcaagac
     7381 aaacatccaa ccgatcatcg attatcaagg ggacctgata ggcatctgtt atttccttga
     7441 cttgttttgc cagttgataa tattgattgg ttgtgagatt tttttctcgc aattggacta
     7501 tggtaacccc tgaacggcag gccgtctcaa cttttgcaag aaagctttcc acggaatctt
     7561 gatagcgatt ggttaccaga tatagtctaa gtgcttctct attcataaac ctctcctttg
     7621 atggtatcta gccaattttc atctcttctt aggagcgaaa gctgattgag tacttggtaa
     7681 cgaaattctt ccaatcccat tccttgaaca actattttct cagcagcgat attgagataa
     7741 gagactgcta agcaagaagc ttcaaaacca gtctttcctt ggctgagaaa aacggctgtt
     7801 aaggctccaa ccaagtctcc tgtccctgtt atccagtcta attcagtaca gccattctcc
     7861 agtacagcaa cttgattctc cgaaacaata aggtccttgg ggccagtaac taagaaagac
     7921 ataccaggat aggtctgaca ccagtctttc aagacttgaa gcaaatcctc cgtttcttga
     7981 tctttagcac tcgcatcgac cccaacgccg tggtgcttta atccaacaag acttcgaatt
     8041 tctgacatgt ttcctttaag gaccgtaggt ctatagtcta aaaggtcttt aactaagctc
     8101 ttacgaatgg atgaagtcgt tacgccaacc gcatctacta ccatcgggag agaagattgg
     8161 tttgcatacg aagctgccat gcggattgct ttttccttct cagctgacaa atgccccaaa
     8221 ttgatgaaga gagcctgact ttgcttagta aaatcaagaa cttcacgggg atcatctgcc
     8281 atgacaggtt tgcatcccag agccaaaatc ccatttgcca gcatctcaca agaaatctca
     8341 ttggtcatac agtgaatgag ggaactagag cctataggaa aaggatttgt caatgcctgc
     8401 atcagtctat cctttcagca aagaaatatc cttgcacttt tttaaagaat tcctgcttga
     8461 ttaaaaatct aaatgcaata aaggaaatcg ctgtaccaat caaggttgct ccgaaaaatc
     8521 gaggagtgta gataaaccaa ctaagcttag cagccgatcc tgtaaagagc accataacag
     8581 gataggaaac aatagaacca ataatacctg ttcccacaat ttctcccaag gcagaaaagt
     8641 aaaattttcg accgtactta taaaagagac ctgctagaag ggctccaaaa gtcgctcctg
     8701 tgagagctaa aggcggaatc ccttgagtcg tcatacggat aaaggctgtc actgtagcca
     8761 tagccaaggc ataaacaggt cccatcatga ttcccgctag aatattgact acactggaca
     8821 tcggtgccat tccctcaatc cgaaagatag gtgtaaggac tacatcaagg gcaatcatca
     8881 tagataaaat ggtcaatttg tgaacttgta gttggtgctt tctcatgttt ctattcttct
     8941 cctttttcta aagactgtaa atcgctcttc catgtctggt gttggtaagc catctcccaa
     9001 aacttggctt ccatatgaac actgatgtgg aaggcatcta gcattttttg cttatctgtc
     9061 tcatcacttt ctcgataaag ctgattgacc agtgctccct cctctctgat ctgttgctct
     9121 aactcatccg taatataagt ttcaatccat tgttgataga gaggatttgg tgatggttta
     9181 agattaagtg atttgcctat atcatggtat aaccaaggac aaggaagcaa gcttgcaaaa
     9241 gctatggcta agttcggttc tgcaaattgc ctataaatat gagaaatgta atgataacag
     9301 gttggagcga ttggatgttg ctccatttcc tggtcgttga tttccaattc cttgaaaaat
     9361 tgttggcgaa taaataactc accctccact aaaccctgag cattttgttt caagagtctt
     9421 ttcatctctt ggtttgaagt cttatcagcc aaaagatgat agatttctga gaaagccttc
     9481 agatagtagg catcctgaat caggtaatag cggaaaatgg caggttctaa attcccctct
     9541 tgtaattgta aaataaaggg atgatgaaag gaagcctgcc aagctttctt ggataattcc
     9601 atcgcaatat ctgtaaattc cataataact cctttataaa aatagactgg tttgaagcaa
     9661 taaaaagaaa agcaggtaga ttaattttgt ttttttagga atataaaaag tccgatagct
     9721 attcttcaac tgtgcatgtt cgtcatatcc gtaagcagat agagctctca ggtaaagatg
     9781 gcgccaccta aagactgtca tcagaacctt actgtaaatc aagggcgacc aaaaatgtag
     9841 tttttgacca cgtaataggc aagcttcttt gagggacttg atttcttgct gaatgagagg
     9901 aaaagaattg aataccacaa tcaaggcata ggaccaagag cgtgatagcc ccttttgagc
     9961 caagtacaag agaagctctt ttagtgaaat agaggaaaca aagacaaggc cgatacaaac
    10021 tgtcacaaag gccctcgttc caagcatgac tgcctgtgaa gcatctccgt gtaactgaac
    10081 tgcccagtag ttggcaaaag atgggaaaat ggcaagtatg atcatccaag ctaacatttt
    10141 aaatcgacgg taatagagca taaagagaat acaaaatgcg actaccgaaa gattcagagc
    10201 aatcgaagga atgaaagatg tttccaagga taaaatcagc aagaagagac tgataatcgg
    10261 tgtctgggtt gctactttga ccatactatc tcacctcccc ttgggtattg ctactctgag
    10321 atgtaagtgg tttggtaatg gtcacttctt tcacatgccg aagaccctga ctagtcatct
    10381 caatccaata atcaaccaca gaaatcaaag ggtctaaacg atgactaatg agcagaaaac
    10441 ttcttccttg attcctctcc tccacaatcc acttgcaaaa ataatggcag gctctatcat
    10501 ccaaacctgc aaaaggttca tctagcaaga tcacggaagc cttactggtc aagatggtca
    10561 ggagctgaag aattttttgc tgaccaccac ttaattgata gggactctta tcgactgcct
    10621 gctccaaatc aaaatatcgt aaagcttgaa aaatccgctg atttctttca gaatcaggtc
    10681 catctaattg aagctcctct cgcagactga ctcggataaa ctgcttctca gcttcctgaa
    10741 caacaccagt cagatcacga tacaaactct ttttcttttt caggaccgaa cccttccaag
    10801 taatgctccc cttatacttt tgaaattgaa gaatagaccg aaagagggtt gatttcccga
    10861 caccattgtc acccaggata caggaaatcc cttgatagaa tgtgaaatca gcaattgaaa
    10921 agagggggcg attaccaagc tcaccagtca cacggttcat atggaatagt tccgggctag
    10981 aagcaacttc ctttgaagca acctgtgtca tctcatagga agggatttga aacacttccc
    11041 ttagttttcc gtctcttagc tccaccatat ggtcgatata ggctttatag tcagataaat
    11101 catggtcgca caaaataact gtcttcccat catagaccaa ctcttttaga atctccaata
    11161 tctcgattct gctcttgcgg tcaatggaag cgaagggctc atccaagaga tagaccctag
    11221 gattcatggc aaagaggaca gccagcgctg ctttttgctt ttccccacct gataagtgat
    11281 ggatgagacg gtgcaagatg tccttgcaac gacattgctg gacaacctct gctattttag
    11341 aatcaatttc ctgaaggtga tagccgatat tttccatggt aaaaaccaac tcctcaaaca
    11401 agctctccat ggtaaattga tgattaggat tttgcaagag aataccaacc gtctggacac
    11461 gttcgacgat agaaagctga ctgacctcgc tcccatctat caggacttga ccgctatagg
    11521 gaagagaact aacttgggca atcatttgaa agaggctgga ttttccagac ccactactcc
    11581 caactaacaa ggtaaaggct tgcgcatgaa aagtaaaatc aaacggctca gagaagattg
    11641 gggactgaat cgctcgtagt tccagaccca tctatgcttt tcctccagtt gcaaactgat
    11701 gatagagttt gacaatggca cgaaccaaga tggtacagaa gaaataaaca gaaataaaac
    11761 gtaccacaag caaggaaagg acaaacggaa gggaaaaggc gtagtaacct aacttaatgt
    11821 attcatagac aaagctaaca agcgtaatcc caatactatt agcagttaga gagagccaac
    11881 tttcatagcg attcttagtt acgataaaac caaattcact tcccaaacct tgaacaaagc
    11941 cagacaaaag agctcctaga ccaaattggc taccataaag gacttcagca agcgcagcta
    12001 gcacttctcc aatcgttgca cttccgactc tcggaacaaa gatggcagca atgggcgcag
    12061 ccatacacca gagaccgaag aggatttcat tggcaaaggc ctgcaaacca agaggtgtta
    12121 agagtagact gagaatatta tacacatatc ctgaaccaac gaaaacccca ccaaaaaaga
    12181 tagacaagaa agcaagcaag ataacatctt ttaactgcca ttttttcaac ataaaaaact
    12241 ccttttttta aagaaaagtg gggcactcaa gaagaccgac ctaaatactt tgtatagcag
    12301 actgaattta gaacagtaca caagaacact aaaatatttc tagaaattaa tttgaatttt
    12361 ctaattgatt tgttcgcatc ttatttcaat ctactatatc atcttcatcc agtttcgtaa
    12421 aagaaaaaac tctaattaca gatacaaatt agagttcagc ttacaagatt agacagttct
    12481 tttcgacata cgaaaaaaac atttcacatt tcccttcgcc agtcttaact gtatcaggtt
    12541 caatgggtat catctcagcc taaagcaccc caaatgtctt tattatttaa ttatgtgatt
    12601 attataacac acattttata ctagttcaag aaattgaact ggaaatacag ccttgcactc
    12661 acaaagacag cagatctttc ttttgcaaaa aacaaatgac ctgtttgatg aattagccat
    12721 tcaagctgaa tctggacata gctttttaaa aaaggaaaat cctacttact tagaatccaa
    12781 ggatagatat ctattgttca ctcatttccc gaacagtttt ttctatattt tttgcatacg
    12841 atattgccga aatgattgaa acgccatcca tattggtctt tataatgtct ttaatatgtt
    12901 tcgtctgtat cccaccaatt gcaactaaag gcatttgtgg caatagtttt ctcatcaatt
    12961 caagaccttc ataacctata gtaccaccag catcatcctt tgactgggta ccaaatacag
    13021 gcccaacacc tacataatct acatattcaa cttttgattg ttgaaattct tcttcgtttc
    13081 ttatagaaag accaattatt ttatctggca tcaattttct aatttcatca acaccaatat
    13141 catcttgacc tacatgtacg ccatcggcgt caatttccat tgctaaatct atatcgtcat
    13201 taacgataaa tggaacattg tattttttac aaagttcttt aatttggata gctagctcaa
    13261 gtttttctaa gccttctaaa gcaccctcac ctttttctcg aaattgaaat aaggttatac
    13321 caccttttaa ggcttcctca acgactgtat atagattttt tccttggcaa gtagtcgttc
    13381 cacaaataaa atatagtttt agtaattctt tatgaaacat cttacttcac tcttttgaat
    13441 tcctttacat cttcatctgt aatctcgtat aaggcattta taaattcaac tttaaatgtc
    13501 ccaggaagat gtccatttgg acgtttttct gccatttctc cagcgatatt gtaaaccaac
    13561 attgctgttt ctaatgattt caattcttga cctttttcta gtccgataaa gcttgctact
    13621 acagctccta ataagcatcc tgtcccaatg actttcggca tcatagcact accattatga
    13681 atcattacca cttctccatt aacagcaatg gcatccactt cacctgttac tactattgga
    13741 atattgaact tctcatttgc tgctagagca atttcgtcaa tattatctac gcccgcacta
    13801 tctactcctt tagatgccac atctattcct actaaagagg caatctcgcc agcatttcct
    13861 ctaatcgctg ctagtttata attgttgatt agatcatctg ctactttttt tctatattct
    13921 cctgctccac aggctacagg atctaaaact gctgggacat tatatttctc tgcaattttc
    13981 agagcagctt ggtataattt ccaattttca tctgtcaatg ttcctatgtt tattaataaa
    14041 ccaccagcat actttaacaa atcctctaaa tctgctggaa actcactcat ggctggtgag
    14101 gcgcccagtg ctactaatcc atttgctgtg aaatttttta ctacatcatt ggttatacaa
    14161 atgaccaatg gtgctttttc ttttaataat tttaaacttg tcatattgaa atccttcctt
    14221 ttcactttat acgatctact gatttcgatt tatttctatc tttcgttaag aatttttttc
    14281 atttacattg aatgatttat actcaatgaa aatcaaagag caaactagga ggctaaccgc
    14341 aggttgctca aaacactgtt ttgaggttgt ggatagaact gacgtggttt gaagagattt
    14401 tcgaagagtc ttacctcatc aaatttgtaa atatcatgag ccttctctag acatcgtaac
    14461 caatatcaaa aaaagctaat tctaaagcga ctgcttgatt ccagcgttgc tgaagttctg
    14521 tcaaatcttc tcgattttta tcgacacgat tgagttcgtc aaccagaaat tgaacccact
    14581 ctgcaaagaa aggacctctg tggagattga tccattccga atgaatatag acttcaggta
    14641 aagccaaatc tttagaaccc cagtctaaat agagaccttc tgcaatgacc agcatgacca
    14701 aaagatgggc atagtctgat gaagccaccg ccgaatacat tagatcctga aaggcttttg
    14761 ttacagggtg caaagtcact tctagatagt cattctctgc tacttttaac tctttaaaag
    14821 ccttttggaa ataaccatct tcatctgctt caagaaagcc tagttgcttg gcaaaacgaa
    14881 gcttggattc aagtttatct gcgtgagcta cgcaggcacc cagcatggat aagaaggcat
    14941 caaagaagtg ataatcttga atcagatagt cctttaagac cttattctca attgtccccg
    15001 caaaaagttc cttaacaaaa cgatgattga ttgcagcctg ccaatccttc tgactgcttt
    15061 ttaataattc tccaacagtc aaacctggct gaaatgcata gtcttgtgtt tccatattta
    15121 cttctcctct ctttacttgt tagtaattaa taaaacacca agaaatatca agcaaaatcg
    15181 taattccact tgatcctttt aaagcacatc gagagcattt gcagagagct aactaaacaa
    15241 gcctatccag tttatataaa caaaaaactc caattacaat caagaattag agttgactta
    15301 caagattaga tcgttcattt cgccatacga aaaaacgttt cacatttccc ttcgccagtc
    15361 ttaactgtat caggttcaat gggtattatc tcagcctaaa gcaccccaaa tgtctctatt
    15421 atttaattac tgaaccagta tagcaaaaaa tgaaagccct agcaagatat ttgaccgaaa
    15481 aatatcttta tatataatat attgaaacta gaatagtaca cctctacttc taaaacattg
    15541 ttagaaatcg atttgactgt cctgattgat ttgtcctatt cttatttcat tttactatag
    15601 ttttcgatag caatttattc ttccaataca cgaagaaaaa cctccacatt cagtggaggc
    15661 aatctgtttt atcaatacaa ttttaagtca cgagggtcaa ctgggaaggt tgggttgtat
    15721 ggattgtgac ggagcttaaa gtgtttgaca tcttcaatgg tctgagctcc agacaattgc
    15781 ataactgtct tcaattccgc attcaagtgt tcaaagactt gacgcacacc gacactacca
    15841 ccgagagcca agccataaat aacagggcga ccaatagcta ccaagtctgc tcctgaagcc
    15901 aaggctttaa agacgtgttg accacgacga acaccagagt caaagacaat cggcacacgt
    15961 ctatcaactg cttctgccac ttcttgaagc gagtcaaagg cagctggtcc accgtcgatt
    16021 tgacgaccac cgtggttggt tacccagata ccagaagctc ctgcagcaag tgaacgttca
    16081 acgtcctcac ggcattgtgg tcccttgaca tacacaggaa gaccagagta ttcagcgata
    16141 aattctacat cgcgtggaga caagcgttgt ttagctgatt tgtaaacaaa gtccattgat
    16201 ttaccagcac cttctggcag gtattcttca acaatcggca tgccaactgg gaagacaaaa
    16261 ccattacgct tatccacttc acgattcccc cctacagtag catctgccgt caagacaatc
    16321 gctttataac cttcagcctt cacacggtcc atgatgtggc ggttgatacc gtcatcctta
    16381 ctaaagtaaa attggaacca atggggtgtc ccttgaaggg cttcagaaat ctctggaagg
    16441 tcaacagtag agtaagagct ggttgtataa agagaaccaa actcatgcac accacgcgca
    16501 gtcgccactt ccccctgttc atttgccaat ttatgagccg caacaggcgc cataatgatt
    16561 ggtgaagata gtttttcacc tgcaaattca atctctgtac ttggattttc aacatcgcaa
    16621 agtgtatgag gaacgatgag tttgtggtta aaggcgcgga tattctctct taaagtgaaa
    16681 gtatcttccg ccccactagc gatatagcca aatgctgctt taggaataac ttgttgcgcc
    16741 attggctcca aatcataggt attgatgaag tctacatgac cttctgcatt gcttgttttg
    16801 tatgacataa aatgccctcc ttgattaagt aagcgtttgc tttttactac acaactataa
    16861 taactctttt ttcaatcatt ttcaagagtt ttgcttaaaa accatcttat tttttcatac
    16921 aatatactag ccctactttc cttaaactct aaactttagt ctatattaag tgaatcgttg
    16981 agattttttg ctgccaggca tttgaactac ttttttattt gcggattcta tctactaata
    17041 ctataaaaaa acaagtgaat aagacaccag aacatcctct aataggacct atggacttat
    17101 atcagtccca tatatactgt ttaagcaaga tactatccta gttgacgcta acttcctatc
    17161 ccacttatta attttttatt tatagtgaat ctgaacaaat caattgggga atccaagtca
    17221 atttctagta ctttttgaac agtttcagcg tactatcgta aaatgaaata aaacatgcac
    17281 aaattgctta gggaatttaa accaatttct aacaatgtct tagaaatcaa agtgtactat
    17341 ttcaacttca atatactaca cttcattttc tccttaaatt cagtctcttt ttgaatcaaa
    17401 aaatcccctg gtaagagcca gaggataaga atttatttca ttgttgggaa gagcaataca
    17461 tcacggatag ttgttgtatc agtgaggagc atgcagagac ggtcgatacc gattcccaaa
    17521 ccacctgttg gtggcatacc gtattcaaga gcttcaatgt agtcatagtc gatgcctgtc
    17581 gcttcatcat caccaagttc tttggcttta gcttgggctt caaaacggct aagttggtcg
    17641 attgggtcgt tcaactcagt aaaggcatta ccgtactcct tagtcatgat aaagagctcg
    17701 aaacggtcag taaagcgttg gtcttcagga tttttcttag cgagtggaga tacagctact
    17761 ggatgtccat agacaaaggt tggttggatt aaagtttctt caacaaactc ttcaaagaag
    17821 gcattgatga tgtgaccaac ctcagtgtag tgtttctcaa ctggaacttt cttctcagca
    17881 gcgatagttt tagcttcttc caaagtcatg tcttgccaga aatcgacacc agtaatttct
    17941 ctgatagcat ccaccatatg aacacgctta aatggttcgt taatcttgat ttcagtacct
    18001 tggtagttga ctgggccatc acctttgact gatttagcag cgtgttggat aatgccttca
    18061 gtcaagtcca tgatgtcttg gaagtctgca taagcttggt aaacttcgat agaagtgaac
    18121 tcagggttat gagtagcgtc cattccttcg ttacggaaga tacggccaat ttcatagaca
    18181 cgttccatac cacccacgat aaggcgtttc aagtgaagct cagtcgcgat acgaagcacc
    18241 atgtcaatgt tttgggcatt gtggtgggtg ataaatggac gggcagcagc accaccggct
    18301 tcattatgaa gaacaggtgt ttccacttca aggaatcctt tttggtcaag gtaacgacgg
    18361 atttcagaga tgatttttga acgagtgaca aagcgttcaa agctttcacg attagaaatc
    18421 aagtcaaggt aacgtttacg gtaaattgtt tcaacgtctg tcaaaccatg gaatttctca
    18481 ggaagaggac gaagagcctt agacaagtgt gtgatgtggg ttgccttgat agagagttct
    18541 cccatatccg tacgcatcac ttcaccttcg acaccaagga agtcaccaag gtctgctttt
    18601 ttgaagattt cgtagttttc ttcaccgaca gcatccttac gaacgtagat ctgaatctgg
    18661 ccttcgcggt cttgaaggtg ggcaaaacca acttttcctt taccacgttt ggttatcaag
    18721 cgtcctgcga tagtagctgt ttcgttttta tcgtgtaatt gttctttatc gaggttggca
    18781 tatttatctt ttaattcttg tgaatttgca gtacgttcaa aacgttttcc gaaaggatcg
    18841 attccttgtt cgcggagcgc agccattttt tcacggcgaa cgatctgctg gtcatttagt
    18901 tcttccatat gttctgtaga catgggatcc tcctagtttt actcaaaatt gaatacgatg
    18961 agtcattttt tgcgatactc ccattttatc ataaataagc aagaaattca cggataatct
    19021 ttaaaaacta aaaagaacct gacgctaaaa tcactggaaa gaagtgaaag tatctcccgc
    19081 cccactagcg atatagccaa atgctgcttt aggaataact tgttgcgcca ttggctccaa
    19141 atcataggta ttgatgaaat ctacatgacc ttctgcattg cttgttttgt atgacataaa
    19201 atgtcctcct taataagtaa gcgtttactt tgtgtattac aaaaatatct taactctttt
    19261 tcaaaacttt taaaatattt tgtttggaaa tttcagaaat tttatgtcta tgataaaaat
    19321 ccttataacg gcaataaaaa atagatatta tccaaagaag attttaagtg ctacaataac
    19381 tgtattattt ctagatggga ggttctattt ttggattgat ccattgttga acaatatcta
    19441 ccactatatc aaaaggcatt ctttctgacc ttgcatattg cagtttgggg aattttggga
    19501 tcctttctgc tcggtttaat cgttagtatc atccgacatt atcgaatcct tgttttggcg
    19561 caagtagcga cagcctacat tgaattgtca cgtaatacgc cccttttgat tcaactcttc
    19621 tttctctact tcggtcttcc ccgaatcggg attgtcctat cttcagaagt ctgtgcaacg
    19681 cttgggcttg tctttttagg aggctcctat atggcagaat ctttccgaag tgggctggaa
    19741 gccatcagtc aaacccagca ggagattggc ctcgctattg gtctgacacc tctacaggtc
    19801 ttttactatg tggttcttcc gcaagcaaca gcggtggcac tcccctcctt tagtgccaat
    19861 gtcattttcc ttatcaagga aacctctgtt ttctcagcag tggctttggc cgacctcatg
    19921 tacgtcgcca aggatttgat tggtctctac tatgagacag acattgcgct agctatgttg
    19981 gtagttgctt atctgatcat gctgctaccc atctcactgg tctttagctg gatagaaagg
    20041 aggctccgcc atgcaggatt cgggaatcca agtactcttt caaggaaata atctcctgag
    20101 aatcttacag ggattgggcg ttacgattga gatatccatc ctgtctgtcc tcttatccat
    20161 gatgttcgga acagtcatgg gaatcatcat gacctcccat tctagaatca tacgattttt
    20221 aacacgattg tatctggact ttacccgtat catgccccag ctggtgctac tcttcatcgt
    20281 ttactttggc ttagctcgaa actttaatat caatatctca ggtgagactt cagctattat
    20341 cgtttttacc ctctggggag cagctgaaat gggagacttg gtacgtggag ctatcacttc
    20401 tctccctaaa catcagtttg aaagtggaca ggcactcggc ttgactaatg ttcaacttta
    20461 ctaccacatc atcatcccac aagtcttaag aagactgcta ccgcaggcta tcaatcttgt
    20521 cactcggatg attaaaacca cttcattagt tgttttgatt ggggttgtgg aagtgaccaa
    20581 agttggacaa caaatcatcg atagcaatcg cctgaccatc ccaactgctt cattttggat
    20641 ttatggaacc attctagtct tatatttcgc agtttgctac cctatttcca aactatccac
    20701 tcacttagaa aaacattgga gaaactaaat gtctgaaact atcttagaaa tcaaggaact
    20761 aaaaaaatcc ttcggagaca atcccatcct ccaaggactt tctctagaaa tcaaaaaagg
    20821 gaagttgttg tcatcctagg gccatctggt tgtgggaaaa gtaccctcct tcgttgcctc
    20881 aacggcttag aaagtattca aggtggagat attcttctgg atggtcagtc tatcgttgaa
    20941 aataaaaaag attttcacct agttcgccaa aagattggca tggtctttca aagttatgaa
    21001 ctctttcccc atctggatgt cttacaaaac ctcatcctag gccctatcaa agctcaagga
    21061 agggacaaga aagaagtaac ggaagaagct ttgcaattac tagagcgtgt cggtttgctg
    21121 gataaacaac atagctttgc ccgtcaatta tctggtggac agaagcaacg tgttgcaatt
    21181 gtccgtgccc tcctaatgca tccagaaatc atcctttttg acgaggtgac tgcttcgctg
    21241 gatccagaaa tggtgcgtga ggtgctggaa cttatcaatg atttggccca agaaggccgt
    21301 accatgattt tagtaaccca cgaaatgcag tttgcccaag ccattgctga ccggattatc
    21361 ttcctcgacc aagggaaaat cgctgaagaa ggaacagctc aagccttctt taccaatccg
    21421 caaaccaaac gagcccagga atttttaaac gtctttgact ttagccaatt cggctcatat
    21481 ctataaagga gattcttatg aaactattca aaccactctt aactgtttta gcacttgcct
    21541 ttgcccttat ctttatcact gcttgtagct caggtggaaa cgctggttca tcctctggaa
    21601 aaacaactgc caaagctcgc actatcgatg aaatcaaaaa aaaagcggtg aactgcgaat
    21661 cgccgtgttt ggagataaaa aaccgtttgg ctacgttgac aatgatggtt cttaccaagg
    21721 ctacgatatt gaactaggga accaactagc tcaagacctt ggtgtcaagg ttaaatacat
    21781 ttcagtcgat gctgccaacc gtgcggaata cttgatttca aacaaggtag atattactct
    21841 tgctaacttt acagtaactg acgaacgtaa gaaacaagtt gattttgccc ttccatatat
    21901 gaaagtttct ctgggtgtcg tatcacctaa gactggtctc attacagacg tcaaacaact
    21961 tgaaggtaaa accttaattg tcacaaaagg aacgactgct gagacttatt ttgaaaagaa
    22021 tcatccagaa atcaaactcc aaaaatacga ccaatacagt gactcttacc aagctcttct
    22081 tgacggacgt ggagatgcct tttcaactga caatacggaa gttctagctt gggcgcttga
    22141 aaataaagga tttgaagtag gaattacttc cctcggtgat cccgatacca ttgcggcagc
    22201 agttcaaaaa ggcaaccaag aattgctaga cttcatcaat aaagatattg aaaaattagc
    22261 aaggaaaact tcttccacaa ggcctatgaa aaaacacttc acccaaccta cggtgacgct
    22321 gctaaagcag atgacctggt tgttgaaggt ggtcattaac tcttaaaagg gactggattt
    22381 taagctccaa tcccttttta agattttacc tataacatcc tgagtctatc taagatgttc
    22441 aatctgaaca cagtgtacat actttatctt ctattgcata tactttatca cataagatac
    22501 gaatatcctc ttcactatga ctagcaatca aaattgttgt ccctttttca ctagagagct
    22561 ttctaaacaa tgttctcata ttttctacac ttgatttatc caaggcattc ataggttcat
    22621 ctagtaaaag aatagaggga ttctccatga ttgcttgagc aatccctagc tttttcctca
    22681 tacctagcga ataagtttta actttctggt ctttttgctc atatagacca actattttca
    22741 gtgtatcatt gatttcctga ttaccaacta ctcctcgtat gcttgccaaa tattgtaaat
    22801 tcttaaagcc actataataa tttataaaac caggttcttc aatcaaagct cccaaattag
    22861 ctggaatttt tctctcagga acaatatttt ccccattgat taacacttct ccataagacg
    22921 gactatataa accagctatt aatttaaaca atacactttt ccctgagcca ttcgcaccag
    22981 taattcctat aatttccccc tgtttacaac taaagttaag gttttgaaaa acacatgtct
    23041 tttttaattt caactcaata ttttttaata taattatttc attcattcta taaacctcct
    23101 cttttgacga gtgaaataga aaatgctttg aaaaagaaag actaaaaata gcaactgaag
    23161 aaacaaatct ccccctacat ccccattccc tcgattcaaa atataaaata gataattagt
    23221 tcgatttcct acaaatagac caccaaacac aatcatgagt aaaaagaaac taacgcaagc
    23281 aaagttcatt tgtacattcg ctcctagtgc gtataacata aagcaaaaca agactaacac
    23341 acaagcattc aaagaatcaa ctataaacaa aactcctata tcccagtttg gtaactgtaa
    23401 cataaattga atcactagaa cttttaccat gattaaaatg agtccataaa gaaaacaggt
    23461 ccaaatctga tacctaatcc agagcttaat agaagaaaat cgaatcactt ccataaagaa
    23521 atcggatgct cttctacgat atacaactgc tagaaaaaat gtatgaataa taaaccaatg
    23581 aagcaaccat atagataaga ctaaaaaaga gttttgactc agattaggcc cttttaaaat
    23641 ttctataaca agtctatcat ttccttctaa ccaataccat aatcctaaac aaatcaatat
    23701 ccaaaaaaga acataacccc aaaagtactt ggtatagatt atcttattca acctccacat
    23761 gtgactactt aactttccca tttccaactt ttacactctc ctccagtttc tatgaacaga
    23821 aaatacagtc aatggaatta tgatagatag taatgtaagc caataaatca atgcatacgg
    23881 attggaattt accatatact gaaaaattgg caataatcca attatcccat tgttcaactg
    23941 ataaatccag aataaggatt ctacaaataa aaaagtaaac agaaatacta agctcatgtt
    24001 tgatttttta aaccaagaaa aactgctaat agtaagtaag gataaaaaga aatagtatgc
    24061 tatataagag aaaaaaaatc ctataaagaa actagcattg tttgcaatac ttataccata
    24121 aaattctctt aaaaaatcaa cctcctttat ctccaaagag aagctaaaac cattactaaa
    24181 tgcaattaga aaaatcaata aaaataaagt cgccgtccaa atccccgtac taagagctgc
    24241 taatttgaaa ctaaaactgg taaagtgctt aattgatttc agacgaatgc gacactccaa
    24301 cctattaaaa tagttattca tcaaataaaa aaagaacaat atatatgtga acggaaagca
    24361 atatactcca gtcgtcatat cttgaagtaa aactaaaatc cattctaata catttggatg
    24421 gattgaatat tggcgacagc gcaataaata tactgtacta gataaaacac aggatagcag
    24481 taatataaaa taaaccaata ctgataaaaa atcttttttg taaaattgaa caaattgttt
    24541 cattatacat agtcctctga atgtagaaaa aatgtaccat aaacaaccaa acaactaaca
    24601 aataaaataa aagcaagatg cccactaact aaggaaagac tgatatcttt ctgatatccc
    24661 aaagctaatg ttgtcacagg ttctaagtaa gatagcccta aaatagccca aaaaatacca
    24721 ccaaccatca tataggcaac tgggatgaaa atagctccta tttttttctt cactagcaaa
    24781 gcactagcta gtccaaaaat agagaacaca gcgccccaaa ctccatacca gagagtcgtc
    24841 acaagactat agagcaactg attagaatca aataattctt ttaaggcacc actataatct
    24901 ccaatataaa tttcctgata aggagtcact aaaagattaa ttcctaataa taataaatag
    24961 gggagaaaaa agactagaaa agaagaaata attgcagtac tacctacaat agccagatac
    25021 ttctttttag aaattcggca caattgtgct gttagaaaat gactctcagc atcctctatt
    25081 atctgactag aatagggcag tgtacagata agtgcagcta ctaggctaat cggtgaaaat
    25141 cctcgaatag aagaagcggc aaaaaaaatc gataaacctt caattttata aataccattg
    25201 aaagcaagga aatttcctaa actcatgcaa agaagggtca aaaataaaga catataaaat
    25261 cgaggtgatt gaacgactcg tacaagatta caaatgaaaa attccatcct tactcctcct
    25321 tataataaaa atagggtgta gcattctttt ttcatgctac acccacaatc aaccatcttt
    25381 aaggcttact ctgacaagta agttaataag aatctggact ccaagaacct gaagtatgaa
    25441 ttcttacatg atttccaaat tgtggcgcca tagctaatct agtaccagaa ccaatataat
    25501 tgtcaccacc tccattatag tacatgacaa tcctagagcc agaccccaat gaatataccg
    25561 gggtaatatc tgacccacta taggcgctac gaatagaggt atttaacctt ttaccgccac
    25621 cagtgctgtc actattatta attccagcag aggcgttttc tttctcaagc tcactagttg
    25681 tatccgaacc ccaacgcggc aacgttaaat cataatttcc aatctgtcta gctaaaactg
    25741 tagggagaaa caaactagat gcaattgtaa ctacgcaaaa aaggaatata tttttcttct
    25801 tttcatgaca tcgtcctctt aagaagtgat aaacaagata gttgattgat caatttgata
    25861 catattacat tttcattata tcaataaaag aaagcgttgt caattatttt atttaaaata
    25921 ttgtcatatt ttaaataaaa tggtaaaaga gactcggtag cctcgtctct ctttatctta
    25981 ctgacctaac cttcttgcca attttcttgg tcttctttaa agcgttttag aagatcaagg
    26041 ccctctggcg tgatgtaacc ttcttcttgg gctagatgga taagctctct atagtttgaa
    26101 agcgtcacaa gtttaacacc agcatctgca aagttcttat ctgcttttgg caattggtag
    26161 ctgaaaatcg ctacaactcc aagtacatct gctccttctc gcttggctgc tgctacagct
    26221 tcaagaactg aaccacccgt tgaaataagg tcttcaacca ctaccatttt ttgaccttga
    26281 gctacgcgac cttcgatttg attaccagct ccgtggtctt ttggtttgct acggatgtag
    26341 gcaaaaggca agtccatctt atcagcaata atggctccgt gtggaatccc tgctgttgca
    26401 gttcctgcaa tcacttctac ttcaggaaag gcttctttaa tagcttccac aaaaccattt
    26461 tcaattaggg tacgagtttc tggataggct agtgtcacac gattatcagt gtaaatcggt
    26521 gacttgatac cagatgccca agtgaagggt tcctctggtt tgaggtaaac ggcttggatt
    26581 ttcaagaggt ggctagcgat atctttagca agtgtcatgg tattctcctt ttatttttct
    26641 aatctagttc tttaattcca gttctgtgtc cattcatcct tgatggcatg ataagctgca
    26701 acaggatcct cagcttgggt aatgggacgt cccactacga tatagtcact gccgatttga
    26761 taggcatcag caggtgtcat gactcgtttt tgatctccaa ctgcaacacc agctggacga
    26821 atccctggtg tcagacagat aaaatctgga ttggtagcct gcttgatgac ttgtacttcc
    26881 tgagccgagc aaacaacacc atccaagcca gcttcagctg tcttcttggc atagtgaatc
    26941 acagactctt gcagactggt ttggatattt tgaaactcct gcatctgagc ttctgacgtt
    27001 gatgtgagct gagttacagc gatcaatttg gcttgactcc caagaccttc acgcgccgcc
    27061 ttcatcatct ctacaccacc agccgcatgg acattagtca tatcgacacc aagctgagac
    27121 aagaccttca tggctgactt gactgtatta ggaatgtcat gaagtttgag atccaaaaag
    27181 acactatgac ccaaaccttt taagtaggac acaatctcag gccccgctgc gtaataaagc
    27241 tccatcccta ccttgagata aaggctttct tctgctggga aaagagctaa aaattccttg
    27301 accgcctcaa aactaggaaa atcaagagca atgattggac gatgttctcg cataggtttc
    27361 tccttttacc tttactagtg agagagtctg gccaacagaa gccacgaaaa aaggaacctg
    27421 ccaacagcaa ggttccacga aaaatgggta gtctccaccc tttcaccgtc taaccttagc
    27481 tgcctctctg gactgcttta aaggttttct attattctat tatttctact agcacttgtc
    27541 aagtaaaaac ttagtcacgt atgtgttgac tgctattgaa cacctcacaa gactctttcc
    27601 aaaagaatag ttaaagactt tcacttagga cagagaaaaa gagtttgctt gttacccttt
    27661 aattgaacaa atgggaattc tgttttattt tgcggatgcc tattcatctt ggcaaagggg
    27721 aagtaatgag aatgcgaatg gacttcttcg tgagtatttt cttaaaccga tttggcaaca
    27781 attaccgaaa aaatccttaa tggtgctttg ctagcttatt aatcaccgtc cccaaaaata
    27841 cttggattac aagacaggtt ttgaagcact tatagaggaa atttaaaaat gttgcatttt
    27901 ttattgcaat ttatcagtta tcttatcacc caaaacttct gcaattagta tgagcactat
    27961 tgttattttt cttttttcgt acactcaaat caaaatatag caataagact attctgtaga
    28021 attgctgtca aaaagatcag ttcatttttc cttcccactt gtgtttataa tcattaaaat
    28081 aactcaatta agaaattttc tttttcctaa tagttatcgt aattaaagtt aatagaagaa
    28141 caatccaaat aagtagtgtt agattaggaa ttagagtttt attccatgaa aatccctccc
    28201 attttgtgaa aaacttagta aacagtccca taaaactata atctgttatc ttcgcaactg
    28261 tcttatccaa accagatagc atcggtaaga aagcaactaa aatcatagca ggaagactga
    28321 taacctgagc tactacttgg ctcttcgcgg ttaaacctat caataaatag aataaaatga
    28381 tggataaaga ggttagaaga acgattgtaa tataattaaa agtatgtaca attgtaactc
    28441 ctaaaataag aggagtagtt cccataatca caaaagttag caaaaaagga agaaacatcg
    28501 ttgataaaat gtattcggat cctttaacac cactcaacag aagagtttgt aaattgtact
    28561 tttctttttc ttcagacaag ataatagtta taggacttcc aacagccaaa gccaaagaaa
    28621 aaggtaaaca catcatcaaa agaactaatg cctgttgatc gttgaccttc ccctgtgttt
    28681 ccataagata tttataaaaa tatgtgaaag caaaaggcac taaaacttgc aataaaatac
    28741 tcttattgga aaggataatt tgacaacgca accataccaa agccagaaac cgtttaagca
    28801 tttagctttc ctcctgttaa tgtgataaaa atatcttcta aagtaggctc acatgaatga
    28861 attgaaaaaa tattttccag atcagcctga gatacctgtt ctagtgatgt aaaatcaaaa
    28921 gttatctgat tcccattata atctgtaacc ttaatctttt tatctttatt atatctttga
    28981 atgagttcag aaggagctcc ttgctcaact aatttccctt tatttaataa ggcaacataa
    29041 tcacataaaa gagttgcttc attcatatca tgagtcgtta gaaaaatcgt tgtccctgct
    29101 gttttcaatt ctaaaattaa ctcatgaatt gttcgagaag ttgtgggatc tagacctgag
    29161 gtcggttcat ccagaaagag tacagcgggt ttgttgataa gagctcgtgc taaaagcatt
    29221 cgttgcctca ttccagtgga taattttcct gctaccatct tgcgactatc atataatcct
    29281 actcgcttta acaaattatc aacacgtgat ttactaatat tataaaattt actataaaaa
    29341 agaagattgt tatacagaga cattttctca taaaatccac ttgtatcgct aaccaatcca
    29401 attctcttta attcaccgct tgttaaattt tgagattttt gtcccaaaat aatagattgt
    29461 cctttatcgg caaggaactg cccagtcaga atattaatcg ttgtggtctt tccagaacca
    29521 gatggtccta aaaatctaac cttctttaac agtgaagctt atattattta aagctatttt
    29581 atcaccaaaa ctttttgata aatggctaac ttcaatcata ctcattgcac ctcctttata
    29641 ttctacattt ttacttaaca tctatttact tatctttatc aaataaacgt cttaaaaaaa
    29701 acaataacat taagcatata accgttagca agattgtttc aatattattg ataatacgat
    29761 acattctcaa gcagtataaa ataattatat atatgcaaat gctcattata cctatttttt
    29821 taaacatact aagcctcctt gctaaataat aaagttatat aataactaag acacactata
    29881 cctaacataa taaatatcca ctggtaactg aataaatgtt ctaaaattaa caagcaaaaa
    29941 taaaatctca aacgatgaaa aaagccatac tatattttcc aatgatgttt gaatattttt
    30001 attgtagtaa gcataatata tagcaaaaat aatacccaag aacaatacta ttaattgtgt
    30061 ttctataaca gtgaactgcc caatagcaga taaaaaagct actcctcctg ataataagca
    30121 aaaacaaact gaacgaataa atgttttcgc tctaatattg ttatctttca ctttattatt
    30181 tttttacaaa ttggacattc tccgttttcc agaacatatt tttcttgact tagagcatga
    30241 tttctcatat tataaacgta agcgttatct attaggattt cattataaca tcccagaaat
    30301 attttaatta ttaaattagt cattatccct cccaaaatag caggcatctc tggtgtagtc
    30361 ggccactttg tcttatcaga taaagtgtac ttatttatat ctttgtttat attccgacaa
    30421 ccaaagcaag aaccgatggt agggatatat attatcagta ataagatagc atccattaaa
    30481 ccctcctgat atgtaggata tcttatgcga tacagcaaat tgattgacaa tttttataat
    30541 atcaatgggc gtatcaattg ctttaacgat aaaatctata ctcccatatt ccgcaacaat
    30601 tttttctaat tcttctactg aagaaacttt aatagaaata ggtactacct gaacatctga
    30661 attatacttg tgtatttttt cagaaagaac attaatcttc tccttaccaa catccgactc
    30721 tgtataaaga atttgcctat ttaaatttga tggttctatt atatcgtaat cagcgacaat
    30781 aagtttcctc actccataca tacttagact tagagatata taacatccta aggctcctgc
    30841 tcctaatact aatactgttt tattctgtat tttattatac tcttcattat aaaataacga
    30901 atagtaacct ttagttctag aatatctact atcaatatct atctcatccg aaattaaaat
    30961 ttgttcattt aatagttcaa atgttagttt actgcctaat acttcttcta tctctaatag
    31021 ttccttacaa ctattaaata gatcgttgat aaattcttgc gaaatttgag gttctatagc
    31081 tatttcccgc atactccgac cacgcaaata cattatacct tcttttttat aagcaaaaac
    31141 ataactattt acgtagaaca tatttcgtcc ttcctctcat atataatata gaaagcagta
    31201 tagaaacaac cacccctcct atactacgaa caataatatt aggtgtcaaa aactgtaata
    31261 gttgactcaa agggaaataa ataataacaa atgctattaa aagttgaact atatattgaa
    31321 aattcaagtt attattgtta gaattcaagt atcttaaaat aataccacta tcatactgaa
    31381 aaaaaggaat tgaattaata aaaatcatac ctaagttaat gataaaaaat aagagtccaa
    31441 gcaatttata cgatgtgaac aataaaacaa gtaaacctgt aagtgataaa atcgaatttg
    31501 aagcaattcc tgctaacata attttcaaaa attgtttttt attttttaag aattgcaccc
    31561 cacttaaatc tacaaaaaaa agccaaatta aacaaaagta gcattattcc acaatttggg
    31621 atctcaattt gataattatt agcaattatt gcatgactaa attcatgtat cgttgcagac
    31681 ataataacaa caagcaacca aaataaaaga atgtttagcg ttattggaaa gttttggaaa
    31741 ttagtcaaaa tatccgccct ataaatatac ataataaaac attgcaaaat aagagccaat
    31801 gggaaaatac caaataggat tttttcaaaa ttcttattaa atcttttata gtttaatttt
    31861 tcagataatg ttatattaaa gtcccaagat attttaaaaa tatttatctt ttttcgtgat
    31921 ttcatagaat ctataagtcc cattttacta agaacaatat aaaatcttaa ataatatttc
    31981 ttccctacta acactaataa gtccgatatg gtaaattctt gacctattag ttgctctaac
    32041 catttttttc ctgtttccca actaatacat gtttcttact agatggtata tatagatgat
    32101 actgtccctc ataaggagta ggtaatatct taatcttatc aacaattctc ataacaaacc
    32161 taacctttaa taaataaaag aggggctaag taaaacatac tctagtccct cagtccgcaa
    32221 tcaataaaat aatgactaat tctattaatc tcttgctgca agactaatac ggaaaattca
    32281 aatgactgtc taaaatgaaa ttgaaaaagc ttgatgttag taaatgaaca aacttcaaca
    32341 accagcaaga gcaaggattg ctaaaccaaa tccgatacct gttgcaagtc cagctgaaaa
    32401 atcactaact ggtactgaaa tttcttcaat ttcctcaaat aaaaagttat cttgcatgat
    32461 tatcactccc tatcttttta acaacaggct attccaatta agagaactac cccagttcca
    32521 agtaaaactc ccccaaaaat tcaccatctg taggggctac gatttcttca atttcttcaa
    32581 ataagaatgc ttcatctgac atatgtgtta ccttcttcat aaaaaattat tttgtaatcg
    32641 attacattgc aaatgtaaca taaagaaaaa cagatgtcaa atattaaacg taagaacatg
    32701 gtcactaaag aactataaga gaaaaggtaa acctagcgac gcgatgagcg ctgggtcgtt
    32761 tgatttcgat tgctctcttc ctcttgtttt ttctgttctt cttcctgttt tttctcggct
    32821 tccttggcct cttgtttggc tttttcctca gcctccataa ttaatttatc cgccacagtg
    32881 taactgtaaa ttccagcttc catgtcgacc acactcggtt ctgacaattg tggcttaatc
    32941 ttactgtaat atggcagttt cttactcatt tcagatagag gaaccaagac ttcgtccgaa
    33001 tcattcatgg tcaatcgaat taaatcggat gtcaccttgc ttggggctaa ttccaccttt
    33061 tggatagccg ccttgagttc tgggctaatt tgagcaagtt ctgagacaaa aaccttgatt
    33121 tgttcactat cattaaagag aactgataaa taagtttctg gtaaactgtt cagactcaca
    33181 gaactagtct caagctgacc actggaaaga ataggataat gattttcacc agaaatatag
    33241 taggccacaa tatcatattc cttgacctta atagtgaact tagttggaaa ttgatagaca
    33301 agttgagctg attcaaccca atagttagac ttaatctgct tttcatattt tgccttgtct
    33361 agcagaaggt taatcgtata atccgaatcc tgaatgcctg aagcctgtcg aatatcatca
    33421 gctgtagttt gcaccgttcc ctcaacacga atatctttca tggtcgcata aggactgagc
    33481 aagtaggcag agacaatcaa taaaagcaga cttggaaata aaatcgtgaa ggctcgcaag
    33541 atatggatac caggaatctt tgctttggct ggtttttcct ttgtagcctt tttagaaagc
    33601 tttttatcct gttcctcctt ctctttagac tctggttctt ctttctcttc tttctctttg
    33661 tcagcctctg aggatgctac tttttcttca gactcttcct tagctgattc tgaatcttcc
    33721 tggtctgttt cactctcctg gtcctgtttg tcctctgact tctcagattc ttctcccatt
    33781 cgagcttgtc tttccttttc cttctcctca gctagagccg cctcttcttc agccttcttt
    33841 tttagatatt cttggtttcg tttctgccat tctgataact ctttcaattc ttcgaggatt
    33901 tctttgtcct catttttctt atcttttgac atttactttc cttatgataa atcttttttc
    33961 aacaattgat aaaaatctgc tagagatttc aattccttag aagccttcat cttagcttgg
    34021 taatcttcct tgtgacttag taagtgagaa agcttctctt ccaaactatc caaggtcaaa
    34081 tcgctttctt gaaggtcttc tgcatagcct ttttttacaa agtaagctgc attttcaagc
    34141 tggtcaccac gactagcttc acgaccaagc ggcacaatga catgcaattt tgctatcgcc
    34201 aagagctcaa aaatcgtatt ggcaccacct cgtgtcacaa caatatcagc caattccatc
    34261 aagggttgat agagatcggt cacatagtca acacgaaaaa gattttggct caactcattc
    34321 aggctagaat ctccagttag attgataata ttgtagcgct ctgttagttc tttcttatgg
    34381 tctgtcacca attggttaaa gacacgagca cctgcagaac cgccaacaaa caatacagtc
    34441 ggcaatttat gattaaagtg gctttgaata tccaccaatt catctggttc tggatttttt
    34501 tgatctgaaa ccttggccac tgctcccaca tgctcaacct tagacaaact cgaagcttgc
    34561 tcaaaggttg aatacatctt agtcgcaaat ttataggcga ttttattggc caagcccata
    34621 gacaggtcag attcgtgaat aaagacaggc actcctgaca cacgcgcagc gataacaggc
    34681 ggtactgaga caaagccccc ctttgaaaaa agggtctgtg gacgaagtcg caacatgata
    34741 aagagcgatt ggacgattcc ccagcaaact ttgaagacgt ccagcatatt ttgccaagag
    34801 aaatagcgac gcaattttcc agtcgcaata gaatggaagg tgacatccaa acctgactta
    34861 aggatttctt ggtgttcgat accacgcttg tccccgatat agtggacttc ccaaccatct
    34921 tcgatgaact tgggcattaa caaaagattg agggtaacgt gtccaaccgt ccccccacct
    34981 gtaaagacaa tttttttcat attattcttt taactccgct actgtgtcga taaagaggtc
    35041 gccacgtact tcaaagttag catacatatc ccagctggca ttggcaggac taagaagaac
    35101 cacatctcct tgagtcgcaa gctcataggc cttgcgggtc gcatctgcaa tatctgtcgc
    35161 ctccacataa gcgacaccag ccttgtctgc tgcccgtttg acacgttctg cagattgacc
    35221 caggatgacc atcttcttga gtccagtaat gtctggcacc aattcgtcaa actcattgcc
    35281 acggtccaaa ccacctgcaa tcaagacgac cttgctgtta tcaaatcctg acaaggcttt
    35341 ttgagtagcc aagatattag ttgatttact gtcgttatag aatttaacac ccttgatgtc
    35401 atccacaaac tggagacggt gtttgacacc accgaaggct gaaagagttt ccttgatggt
    35461 ttgattgtcc acaccacgaa gcttggctac agcaatagtc gcaagggcat tttccacatt
    35521 gtggctacct ggaacaccga tttcattcgc tgccatgact acttcaccac ggaagtagag
    35581 ttgaccatct tccagataag ctccatcaac cttttcaagt gttgaaaatg gtacaacagt
    35641 ggcttctgtc ttggaagtca agtcttttgc caagtcttga ttaaagttca agacaaggaa
    35701 atcagctgct gtcatcttgt tctggatatt ccacttggct gctacatatt ccgaaaatga
    35761 cccatggtag tcgatatgag ttggcatgag gttggtaata accgcaatct ctggatggaa
    35821 ttcttgaaca cccatgagtt ggaaagaaga aagttccata acaagcgtgt ccttatctga
    35881 tgctatttga gcaacctgac tagctggata gccgatattc cctgataaaa gaccatgttg
    35941 cccagcagca gtcaaaactt ccccaatcat agtcgttgtg gttgtcttac cgttcgatcc
    36001 tgtgatacca ataatcggtg cttctgaaat caaataagcc aattccacct cagtcaagac
    36061 tggaattccc ttggccaaag ccttttcaat catgggattg ttgtagggga tacctggatt
    36121 tttcaccata agggcaaact cttcatccaa gagttccaaa ggatggccac ctgtaatgac
    36181 cttgatccct tcttccagca aactttgggc agctggattg tcctcgaaag gtttcccatc
    36241 atttactgtc acaatggcac ctagcttgtc caacaaacga gctgcagatt caccagactt
    36301 ggccaaacct aaaacaagga ctttcttatt tttaaattga tctattactt tcatgtctcg
    36361 aactccattt ctactcctac tattttacca tttttatgga aataaaaaag ccacaaagtg
    36421 tgtttgtgac tctttcttct aactgaatct taccatatca tctatgtgat aaatcggtaa
    36481 ctcgaatgac ctgatccact tgttcccaaa taagaggatt gtgggtcgca ataataatgg
    36541 tccgattcgg attttttaaa gattctagga tggaaagtaa ttcctcagag tttttggggt
    36601 ctaaggaagt ggttggttca tctgcgagga tcaaaggtgg atcctttaaa attatcttcg
    36661 ctaatgcaac acgttgtgct tctcctcctg ataactcaaa tataggttgc ttcaaatcca
    36721 aataagagag gtttacacag tttagagctt gtttcatcaa agagattttc tctttttcct
    36781 tcaacttttt accaactaaa cccagattga gattctcttt gacggtttgg ctttcaatta
    36841 agccaaaatc ttgaaataag tatcccaagt aatctctaaa gaaaacagaa ggcttgatgt
    36901 ccttaagaga agtaccatca tagatgattt gtcctttgtc atatggctct aatcgtccaa
    36961 tcatattcaa gaatgttgtc ttaccacagc cacttgtacc gattaaggca taaattttcc
    37021 caccttcaaa atgaagattt gtatctgaaa atagctgacg gcttccaaat tttttagata
    37081 tattctttag ttcaatcatc ctattttcct ttcataattg tcatagaaac acgagattct
    37141 ttctgcgctt gacggtaaag cgtcagaact gcactagcta gaaagactaa taaagtgagc
    37201 aagccaatca ccaagtctcg actgcttaaa ataaagagac tagcaccaaa tacaaaactg
    37261 gcaaattgac taaccatata ctgagcatgt gtttcaaaaa atcgtaaacc tgaaattcgt
    37321 ttaatcaaaa tatctcggcg gaattgctcg aaatatagaa gattgacaga ataaaatagt
    37381 aataaggaac tagctatccc cacaatagct cctaagatta aagttgctgt ttcagtttga
    37441 acttcattat aacgagttag ataaacactt cttccttctt taagatagga tacttgctca
    37501 taaattccag ctttcttcaa gagttctagc ccactctcat atcctttgat aaagagttgt
    37561 tttccagcat tgatagacca actagataag gatataaaac tatcacctgt agaagtcggc
    37621 gtgaatacca ctaaaatcgg atcagtcaaa tactgagtag atacgggatt ctcaccgtta
    37681 ttataaacaa accgcttttc tcccattgaa agataactaa cgtgcgcttt catctcataa
    37741 tccaaaggag cacttgcctc ctcaccagat tttccataat aactcaatct ttcttcaaaa
    37801 actttcttaa gttctgcttc tcgagagcgc aaatgttctg ggagcaagag gataaactca
    37861 cctttttgga gatgggctaa cttctgtttg gtctcagcat ctaccacgac cttttccttg
    37921 tccaaataac tgggactaac atagagcgta ttagcatctg gactataggt atccagtgtc
    37981 tctccctgtt cattttttcc ttgtggattg gcaaaatgga gcagattatc ctttacataa
    38041 agagcttgtt cttcttcgat tgcttccttg gcaaaggcat accacttgct ctgattttct
    38101 gtatcttttc ctctatcacc taagccaaaa gaaatttgat aatagtctgc tctatcctgc
    38161 catgcttgtt ttgaaatttc aagttctttc aatcgttggt aagacatcaa acctgtctta
    38221 acagcgtagc ctactgtaaa gacagcaacc aactgacaca atagggttaa aatcatcagg
    38281 cgtttaaggg gtaatctccc cttaataacg ggaactaatg ctttgtaact caaactcatt
    38341 agataaagaa gcattagtaa aattgaaatc gccaataaaa acaacagata gaaactaatc
    38401 ccaaaaccat aggtggctaa caagatagga taaaacaaac cttgactaaa aagaacgact
    38461 cccccaccta ggaaggaaag gagggctgat agaaggagcc atttgatatc agtagataaa
    38521 gaatgcccca tgatggataa gagagtctga ccagaaaaga gttttatacc tgctgctctc
    38581 atttccttaa tccgagtgat aatcactaaa gcaaagaaag ataagccaaa tattgctaaa
    38641 ctaattaaaa taaggggatt tagtaatatt cgaaaagcaa gaaaataggg cggtatcttt
    38701 cggtcagcac ttgctttata acccaaatct cctaatttat cggcaagctt ttctttcgtc
    38761 aaggagcctg acaaaaggag ataactattt agcggatcac tacgttcacg actttcttgg
    38821 ctagcttctt ggaattcttt tggtaaagtt ccctgaccat aagttgcata agtaaagtga
    38881 gtcgtcccat ccttactcgg ctctacaatt cttctagcta ttaaactctg ttctgagttt
    38941 gcaaaattct ccaattcctg ttcaaatacc tcacgcgtcg gttcctgagt atcttttttg
    39001 acacgaagta aagaaacgga atcatagctt gcatataaat attgtggcgc acgtaagaca
    39061 ataatccaag caaggaagaa gctgagaaaa aaagttgata ataatatgaa tagtttcttc
    39121 atagtagact ccttgtaaac aaaattcccc ctgtaatttc ttacaagggg aacgatttaa
    39181 atcaatgaac gattagtcat aatcacagta aaatgctact tgttctcccc atttagtcca
    39241 aatccatgca taggaggttt ttccagcaga agcttctcct ttatctgaat gactattcca
    39301 tctacttaca agagaagaat aatgatattt tttaccatga tagtaatttg aaaaagccca
    39361 accacctcct gaaccttctc catacgtcca tactcctcca tctggatatt gtacagcagc
    39421 tgatgcagct cccaataatg taaaacttga aataagagct agagcaagta atctatgttt
    39481 tttcgttttc attttatttt ttctttcaaa aaaagcacac cttgagcaac aatgcaacaa
    39541 aataaaccct cctctctctt ttgttgaaac cgctttctta tgtgataaaa atatcatttt
    39601 tattatttgt tgtcaaggaa aaaatcgaat tttttagata ttttactaca ttgcctctat
    39661 gaataatatt atatagtagt tttattttaa aataatatgc aaccagtact aaccaaatat
    39721 aaaatagatg ccattaacga attttattca agtttttccc attcatacta tccaagcaaa
    39781 agagatgatg ttatagtaca aaacaattca aactattgta aaattcctag caaaaaagag
    39841 agccaaaact ctctttttta tcttctttta ctttttttga ctggcatgag tgtaatgtct
    39901 ctaacactaa agtaagctag gatcaacatg gctattgcta ggaatatttc tgttggtaat
    39961 tgaaaaattt tcagaaaaga tagaaccaat aaaatcaaga gtgccactaa aatacatacc
    40021 atagcgacga tattgactgt ccctttaatg ctttctggtg tcgcaaatac atagagtagg
    40081 agcagtaaaa ttcctaggac taaatagacc atctttctct ctttctagct cttattcagc
    40141 tgattttttc ttcttgttag ctttctcacg ctctgctttg ttaaggattt gtttacgcaa
    40201 acggatagac tcaggcgtta cttccatgta ctcatcgtcg ttcaagaact caagagactc
    40261 ttcaagtgtc aagatacgag gcgtcttgat aacagctgtt tggtccttag tagctgaacg
    40321 aacgttggtc atttgttttg ccttcgtgat gttaactgtc aagtcatttt cacgagagtt
    40381 ttcaccgatg atcattcctt cataaacctc agtacctggg ttgacaaaga tcgtaccacg
    40441 ttcttcgata gacatgattg agtaagttgt agccttacca gcatcgatag aaacaagggc
    40501 accacggtga cgtccaccaa tttcccctgg aatcaatggc aagtattggt cgaaggtatg
    40561 gttcatgata ccgtaaccac gagtcattga caagaactca gttgagtatc caatcaaacc
    40621 acgcgctgga acaaggaaga ccaaacgagt ttgaccatta ccagttgaaa tcatatccaa
    40681 catttcacct ttacgttcag aaaggctttg gataacagac ccttggtatt cttctggagt
    40741 gtcgatttgt acacgttcaa atggttcaca tttaacaccg tcgatttctt ttacgataac
    40801 ttctggacga gatacttgaa gttcatagcc ctcacgacgc attgtttcga taaggattga
    40861 caagtgcaat tctccacgtc ctgaaacagt ccatttatct ggtgaatcag ttgggtcaac
    40921 acgaagggaa acgtctgttt gcaattctgc ctgcaagcgt tcttccacct tacgagaagt
    40981 tacccattta ccttctttac cagcaaatgg tgagttgttg accaagaaag tcatttgaag
    41041 agttggctca tcgatgtgta ggattggaag agcttctact gcatctgtcg gagtgatggt
    41101 ttcaccgaca aagatgtctt ccatacctga aacggcaatc aagtcacccg ctttggcttc
    41161 ttggatttca cgacgttcca aaccaaagaa accgaagagt tttgtaacac ggaagttttt
    41221 agttgtaccg tcaagtttag aaagggtaac ttggtcccca accttaactg taccacggaa
    41281 gacacgaccg ataccgatac gtccaacgaa gtcattgtag tccaaaagtg acacttggaa
    41341 ctgcaaaggc tcatctgagt tatctactgg agctgggata tggtcgataa tcgtgtcaaa
    41401 gattggtgcc atagtcgctt cttggtcagc tggatcatct gacaatgaag aagttccgtt
    41461 gatcgctgaa gcataaacca ctgggaaatc aagctggtcg tcatctgcac caagctcgat
    41521 gaaaagttcc aagacttcat ccactacttc tgctggacga gctgatggct tatcgatttt
    41581 gttaacaacc acgattggga caaggtcttg ttccaaggct tttttcaata cgaaacgagt
    41641 ttgtggcatg gttccttcat aggcatctac gaccaagaca acaccgtcaa ccattttcat
    41701 gatacgctca acttctccac caaagtccgc gtgtcctggt gtgtccataa tgttgatacg
    41761 agttccgttg taagcaacgg cagtattttt agcaaggatg gtaatcccac gctctttttc
    41821 gatatcgttt gagtccatag cacgctctgc caattcagta cgtgcatcaa gcgtttctga
    41881 ttgtttcaat aattcgtcaa ccagggttgt tttaccgtgg tcaacgtggg cgataatcgc
    41941 aatgttacgg atatcttctc ttaattttgt catgatttcc tctataatat tcaaaattta
    42001 ttttctaact gaacgattat accataattt caaataaata acataactca agcaagtgta
    42061 aatgttttca ctccgctttt cttttcacgt caagcctttt caaagcaagc gacttatgat
    42121 aagataggca cagtatgcgt ttagataatt tattagccca agaaaaagtt agccgaaagg
    42181 ccatgaagca agcactcctc agaggggaaa ttctagtcga tggttgccca gcccgatccc
    42241 tagctcaaaa tatcgataca ggactacaag aactcctttt tcaggatcga atcattcaag
    42301 gctatgaaca cacctatctt atgcttcata agcctgctgg tgtcgttaca gccaacaaag
    42361 acaaggaact tccgaccgtc atggacctgc ttccatctga catccagtct gacaagctct
    42421 atgccgttgg ccgactggac cgagatacaa cgggactcct cctcttgacc gataacggtc
    42481 ccttgggctt tcagctcctc catccccaat atcatgtcga taagacttac caagtccagg
    42541 ttaatgaact tctaacacct gaccatatcc aagcctttca aaagggaatt gtctttttag
    42601 atggtactgt ctgtaaaccc gcaaaactag agattctatc tgcaagtccc tccctcagtc
    42661 aagcctctat caccatttca gaaggaaaat ttcatcaaat caagaaaatg ttcctctcgg
    42721 ttggtgttaa ggtgactagc ctcaaaagaa tccaatttgg ggacttcaca ttgaacccag
    42781 atttagcaga aagtaactac cgccctttga accaaaaaga gttacaaatc attaaaaact
    42841 atttagagat gagtcgataa aacaaaaaaa gctttaaaac taaagctttt ttcttttatt
    42901 taccgaaaaa ttaaggcgat tgctacaatc cagttaacta cagaaatcac aattcctaag
    42961 atattaagaa tcttttctat tttatagtct aattgtgact ctttttggta tgaaatagcc
    43021 aagaccaatc ctatgatacc caaaatcaag cctacaattg gaaataacaa accaagaata
    43081 atcgacaaga tacccacaaa aagtggattt ttcttctttt ctttcatgtt ctaagaactc
    43141 tttaaatttt atacaaatta attatactat aaaacaatag cttcatccta tcattcgact
    43201 aatttggaaa taaggttagc tagtcttcac tttccctttc caagaatcca agccataaga
    43261 aaggatataa atctcagaaa aaccttgttt tttcaagtaa agagctgcat ttgtaactcg
    43321 ttgcgcacgt tggttctcgt agagaaggac aggtttatct ttacgaaggg ctgcaagact
    43381 agttttcaac tgacttgaag gaatattgcg tgcaccaagg atatgttttc tgtggaattc
    43441 tgctgggtcg cgcaaatcaa tcaattgacc cgtacgaatc aaggcttcaa actcctcatt
    43501 gtccacaatt ttagccgcac gacgaatacg aagatagtta aagcccatcc acgccaacat
    43561 tgctagtata agtgcccaca aaatccaagt aaccattagt tcttttctcc atttttctca
    43621 atataatcca attctacctt gtgctctctg cgaagaactg cttctgcctc tagatagtct
    43681 aatttatcca tcaaccctgc atcgtaaatc cgagatagtt ccaacttcat cagttcaata
    43741 tcatataagc gttttcccat gtaaacaata ataccaaatc gtttgaggaa ttgctgcaca
    43801 tcatagaatg ttttcataag actcattcta gcaaaatttt gtgttttttt caagaagaga
    43861 ctcacacaat gctccttatt ttcctatctt ctttggcgat tctaaggcaa gtgtggtaca
    43921 ataaaaacat gagaattcaa caattacatt atattatcaa aatcgtcgaa actggctcta
    43981 tgaatgaggc agccaagcaa ctctttatca ctcagccaag tctttccaat gctgtgagag
    44041 atttggaaaa tgaaatgggc attgagatct ttatccgcaa tcccaaggga atcaccttga
    44101 cccgtgatgg gatggagttt ctctcttatg cccgtcaggt tgtcgagcaa actcagcttc
    44161 tggaggaacg ctataaaaat cctgtcgccc accgcgaact ctttagcgtt tcgtctcaac
    44221 actatgcctt tgtggtcaat gcctttgtct ctttgctcaa gaaaagcgat atggagaaat
    44281 acgagctttt ccttcgtgaa actcggactt gggagattat cgacgacgtc aagaacttcc
    44341 gcagtgaggt cggggtcctc ttcttaaaca gttacaaccg tgatgtttta accaagatgc
    44401 tggatgacaa tcacctacta gcccaccatc tcttcacagc gcaaccgcat atctttgtca
    44461 gcaagaccaa ccctctggca aagaaagaca aggtgaaact gtctgatttg gagaatttcc
    44521 cttacctcag ctatgaccaa gggacgcaca actccttcta cttttcagaa gagattcttt
    44581 ctcaagaaca ccacaagaaa tccattgtgg tcagtgaccg tgccaccctc tttaatctct
    44641 tgattggttt ggatggttat accattgcga cagggatttt gaacagcaac ctaaacggag
    44701 acaatatcgt ttctatccca ctggatattg atgacccgat tgagctggtc tatatccagc
    44761 atgagaaaac cagcctatct aagatgggcg aacgctttat cgactatcta ctagaagaag
    44821 ttcagtttga tagttgagaa atgataagaa ccaatatgta ggctagcaac aacctgcaca
    44881 ttggttcttt ttacttataa ttaaaagttt cccctgccaa cttatcagct agcttgggaa
    44941 agagagtata aaacttatgg gctaggttca acaaaatcgg gagattgagt tctcgtttat
    45001 tttttcctat aatcttgaca atctttttag ccactgcatc tgcctctaag aggaagcggt
    45061 caaccgattt aagataagtt ccatctgggt cagcttggtc aaaaaatcct gttcggattg
    45121 gacctggatt gactgttgtc acatagactc catagggcat aagttcgagt cgcagagcat
    45181 ttgaaaaacc aatagccgca aacttggtcg ctgagtaaag actagacttg ccagtagcta
    45241 ttagacctgc catgctgacg atgttgatga tatgcccttt gctgctttcc ttcatacgag
    45301 ccgcaaggtg acgagacaga ttcatcaggg caaaggtatt gacctcaaac atctggtgaa
    45361 tatctttatc agcaatctgg tcaaatccct caaaaatccc gtaaccagcg ttgttaatca
    45421 agacatcaat cttgccatag cggagataaa gatcagttac cagagcttct agggctgaat
    45481 cgtcggtaat atcaatttca atcaattctg catgggaata atttccgtag agttgggcta
    45541 atttttcctt atttctacca agcaagatga gttggtcatt gggcaggagt ttgaccattt
    45601 cttgagctag accaccgcta gctccggtaa tgagaatagt aggcatactt atcctttctg
    45661 tgactgctag atttccactt cttccaagtc tttgaccaca tggacatttt caaaaattgt
    45721 ggcagcgtcc ttcttgagtt tgcttatatc ttttgagagg aaacgggcac tgatatggtt
    45781 gagtaggagg cgtttggcac ctgcttctac cgctacttgt gcagcttgca tattagttga
    45841 gtgaccatgg ttacgagcaa ttttttcatc acccttgcca taagtggact catgaactag
    45901 gacatctgca ttgacagcca gacgcacact ggcatccgtt tttcgagtgt ctcctaaaat
    45961 agtgataatc ttacctggac gtggcgctga gatatagtct gctgccttga tttcagttcc
    46021 gtcttccaaa acaagatcct ggccgttttt gattttacca aaaagcgggc cgaacggaac
    46081 accagcagcc ttgagttttt cagcatccag cgtcccttct agatcctttt gcatgacacg
    46141 atagccaaca cagaaaatag tgtggtccag ctcctctgca tacacagtga atttatcggt
    46201 ttcaagaatt ttacccagag aatcttggtc aaactcatgg aaatgaatgc ggtagggcag
    46261 acgagaacct gacacacgaa ggctggttaa gacaaatgac ttgattcctt gaggtccgta
    46321 gatttccaaa tctgtctgct cttcattggc ctgaaaggca cggctagaaa ggaaacctgg
    46381 caaaccaaaa atgtggtctc catgcagatg agtaataaag attttgctga ccttacgtgg
    46441 tcgaattgtg gtttccagaa tgcgattttg cgtaccttct ccacagtcaa agagccaaac
    46501 ttcgttaatc tcgtccaaaa gtttcagggc gagacttgaa acgttgcggg ctttagaggg
    46561 ctgaccagcc cccgttccta aaaattgaat atccattcga tactttctaa ttaatcaata
    46621 tataacatgg ctgtgcggtt ttccgatcgg aaatagcgtt tgccagaaaa agcagcagct
    46681 tcttgcaata aatcctcttg gctgtagcct ttgagacgtt ttcgaccatc agccaatctt
    46741 tccaaatcag tcaaagctgt gagactttct aggctgacaa cttcctcgtc cttgacaggc
    46801 ttcatgtaaa tcttaccaga ctcttcaaag actaattgat gggagaaaat ttgcgcaatt
    46861 tcaaagagca agtcatccga gattttctcc tcattttcag agaaaatccg accaaagccg
    46921 tcactctcat aacaaaaacc aaaggattta ccagacagat taagccgaat aaaaggctta
    46981 ttttctaggg tgaaacttgg ctcagtattg taaagattca gttcctgact gagttctgca
    47041 aaataatccg tcgcagcctg aggacttttt ttctgataga gttctgcaaa gtaggcatta
    47101 acaacacttg gcggaggtgt aataagtgtt aactgctcct gctctgtttt accagctaga
    47161 agctgatcca gatagacctt gtccagactt gtataacctc catactttag agccaaagtt
    47221 ttaatatcag tcataaaatt cttctaacct ccatttattt ttctcggaaa tgtagcctgt
    47281 aatcacttcg ccgtcttcct gataatcacg ttcttccaga attgcaacac tctctaaatc
    47341 atgaatcttg taggactttg aaaaaggcac tcgcagggta aatgcttcaa aaatttcctt
    47401 aatcttatct agcaataatg cttgcaagtt ttcacgactg tcctcagact tggcagaaat
    47461 gagggtatat ggcgtttggg taggcgtgaa atcctccacc aaatccgctt tattataaag
    47521 cgtcaagtga ggaatatctt ccatgtccag gtctttcatg atggagagaa ccgttttttc
    47581 atgctcctcg tggtaaggat tgctagcatc gataacatga accagaaggt ccacatgctt
    47641 gctttcttcc aaggttgact tgaaactgga caccaactct gtcggcaaat cttggataaa
    47701 gccaacagta tctgtcaaag ttacttggag attgcctccc agatgaatac tcttggttgt
    47761 cgcatccaga gtcgcaaaga gctcatctgc ttcatactgg gtcttactgg tcaagatgtt
    47821 catgatagtt gatttcccag cattagtata accaatcaaa ccaatcttaa aagtgctaga
    47881 ctccaaacgt ttttctctga cagtcgcacg atttttctca accaccttaa gctggcgctc
    47941 gatatccgtg atttgattgc gaacgctacg acggttcagc tccagttggc tttcaccagg
    48001 accacgggaa ccaattcccc ctgcctgacg gctgagcata atcccctgac caaccaagcg
    48061 aggcaagagg tatttgagtt gggctaggtg gacttggagc ttcccttcat ggcttcgagc
    48121 ccgcatggca aagatatcca aaatcaactg catacggtca atgaccttaa caccgagaac
    48181 ttcctctaga ttgacattct gccttggggt cagacggttg ttgacgatga cagtagtgat
    48241 ttcttctgca tccaccataa gcgcaatctc ttccaactta ccagagccga cgaaggtctt
    48301 ggaatcatat ttttcacgtt tttgtctgta gctatctaca acgactgccc ctgccgtttt
    48361 cgctaaacta gccaattctt ccatggagag gtcaaaactg tccataccct gcaattccac
    48421 accaatcagc aggactcgct cctctttttt ctccgtttca atcatctaaa aactcctcta
    48481 tctggcttaa aatgcggtct tgtacaccag attctccaat ctgataaaag gtgacctgca
    48541 tgcgattacg gaaccaggtc agctgacgct tggcaaaacg acgggtcgcc tgtttaagac
    48601 tctcacgagc ttcctccaag gtctgctctc cacggaaata aggaaagagt tccttatagc
    48661 caattccttt agcagcctgt acattagggg aatggtcaaa cagccacttg gcctcatcca
    48721 aaagcccagc ctcaaacatc aaatccactc ggtggttgat acgctcataa agttgactac
    48781 gttcatcatc caagcagata atcagcggtt catacaaaat ctcttgattt tccaaatcct
    48841 gaccaaaatg ggcaatttct aaggcacgca tagcacgacg acgattaaac tggggaatct
    48901 caaggcctgc ttgctccacc aaatgggcta attcctcatc tgaatatggc tccaaactag
    48961 ctcgataagc taaaatctcc tcatgaggag tctccccacc taggtggtaa ccttctagca
    49021 agctctggat ataaagtcca gtcccaccgg cgataatggc tagcttgcca cggctgtgaa
    49081 tatcctcaat agtcatctta gcttctgaaa caaaatcaaa agccgagtaa gactcagtta
    49141 tctctctaac atcgattaaa tgatgaggaa cagctgcctg ctcttctgga ctagccttgg
    49201 ccgtcccaat atcaagtcct cgatagactt gctggctatc tccactaacc acttcgccat
    49261 taaagcactt tgcaacttca atagctagag ccgtctttcc aacagcagtc ggtccaacaa
    49321 tcacaattat ttttgttttc atcttttttc cttgaaaaat tcccattttt tcgttactat
    49381 tattataaca caaaaaggtc agtcagaaaa atgtgacctc ttgaggaggc tggctgattg
    49441 agaatataaa ggaggaagac tcatggctaa aggattcgct aaaggtcttg taacaggtgt
    49501 cgcaggaact gtcgctgccg ttgcaggtgc agtatacgca tttaaaaaga aagtaatcga
    49561 accagaagag caaaaagcag ctttcatcga agaaaaccgt aaaaaagcag ctcgtcgccg
    49621 cgtatcacgt taagaaacaa aagaagttgg gattattctc aacttctttt ttctattctt
    49681 ttaaatagct aggtcaaact tcaactgtgg cttaacaggg tcataatcca ccaactcaaa
    49741 atcttctgct ttgatatcaa agaaattagt cccatcagga acatttaaaa ccaagcgtgg
    49801 ttggcagttt gacggctccc gacggagcaa ttcctgagct tgttcaaatt gattatcata
    49861 gatatggagg ttgttgatga agtagaagaa cttcccaacc ttccagccaa aatgtttagc
    49921 aatcatcatc tgcaaagcca catactgcat agcgttgatg tggtgggcca ccagcatatc
    49981 attggagcgc tgggtcaagg tcgcatccag atagatttcc ccatcaacac gccgaacatc
    50041 aaacatggtc tgaaaggcgc acgggagcag cccatctgtt tcttcgaaag cttggtaatc
    50101 ccagagagaa ataatattgc ggcggttcca aggattggtt tccaactgtt tgagaagctt
    50161 attgataatg tcgtgtttct taacaacggc accatagcgc tcaccaatgg ttcccgtgtc
    50221 tccaacttcc cagtcattcc agtagtgaac attgtacttg tcattaagca cttctaagct
    50281 atttgactgg tcttggtaaa tccagagaac ttctttgatg gcggatttga ttgcaatggg
    50341 acgcaaggtt atgataggaa attctccttt agataagtcg tactcggaaa aggcaccagt
    50401 tacatacttg gaattagcaa cagtcccatc cttgtactta ggacgagcct gctctgagaa
    50461 aacaccttcc tttagaatgc gttcaatatt ctctttaaaa atcgtatctg cttttgtcat
    50521 ttactctcac ctcattcatt gtcctaacta gtatagcata aaaaataaaa gaggaacatt
    50581 actaactcta ggttagcatt ttcctctctc attatcttat tgcaatacaa gtgatgctgc
    50641 tccgataact ccagcgtcat ttcctagagt tgcaagagct aatttagtag atgtgcgtac
    50701 ttgtgggaaa gtattttcgt catagacttt ttgaacacct tgtagaagga attctcccgc
    50761 agctgacaca ccaccaccga tgacgattgt tgatgggttt aggattgaac caatgttagc
    50821 acaagcgatt cccaagtaac gtgagaagtt acggtaaaca atcaaagcaa ggtcgtctcc
    50881 ttcttttgcg agatcaaaga cagtcttagc agttacttct tctccgttat caatcaagcg
    50941 tttcaaggct gcatcgcctt cgtattcatc ggcatagcga cgagtcaagt tgacaattcc
    51001 tgttgcagaa gcgactgtct caagacagcc tttcttaccg caagtacatg agattggctg
    51061 gtcaaagtca acagtgatgt gacccaactc acctgctgca ccagcaacac cgtgaagcaa
    51121 tttgccttct gcgacgatac cgccaccaac accagtaccg agtgtcataa agacaacatc
    51181 tggttggtta tcaccagcac ccatccagcg ctcaccaaga gctgctacgt tggcatcatt
    51241 atcgatgaaa aatggaatgc ccaaagcttt ttcaatcttt tgtttgattg gttgaagggt
    51301 tttccagttc aagttgtagg caccgataac agtccctttg tcacggtcaa ccacacctgg
    51361 tgatcccatt ccaatgcctt ggaagtccgc tgctgccaat ccaagcaagt ccaaacgatg
    51421 ttgaatagac tcaatcatat catcaacgat atgacttccc tcatccaaaa tgttggtctt
    51481 gattgaccat tttccttgga tttctcctgc tgttgttaag attgcaaatt tgatagaagt
    51541 tccaccaagg tcaatcccaa taatcttttg actcattata ttctcctttt tcattgtgta
    51601 gtaattgaaa atgcttacag tactagtata tcaaaatcca ttcacttatg caaaggtttg
    51661 cgtaaatgaa ttataaggaa ttttttcgcc taccagtatc tgttaaccat ctaaatgatc
    51721 aatggcatat tgagctgcat catttgaaaa tttatcaaaa tcagaagtta attgtctata
    51781 catacgtttt tttgacatgt ggaataacga attataactt tttgcctttc ctaaagcagc
    51841 agaatattca ctattgctat cattactaga agaagctgta cttgcttgac cttccttcca
    51901 aactccgtca gcgccaacat aataacgtcc accatcaacc cattcattga cagccatttt
    51961 accatccgat tttagatagt aatttccttg ccatgtacta taagcataag aaccatctga
    52021 tgtcaaataa taccaagctt gataggtggc atcataaacc cattcacctt tagccatttt
    52081 accatctgat ttcaaatagt agtttccttg ccatgcattg cgagcatatg aaccatctga
    52141 tttcaagtaa taccatgctt ggtaagaaga atcataaacc cactcacctt gtgccatttt
    52201 accgtttgat ttaaggtaat aagctccttg ccatgcattt tttgcataag aaccatctga
    52261 tttcaaataa taccaagctt gataagaaga gtcataaatc cattcactct gtgccatttt
    52321 gccatcagct ttcaggtaat agtttccctg ccatgcattt ttcactagat ttccatttcc
    52381 atcaaaatag taccaagaac cgtcctgctt aacccaacca cttgctgtgg atgaagttgt
    52441 atcagtttga gttgtagccg cttgttttgc tttaaaagca cccttaggag catttttcaa
    52501 ttcgcaagcc acaccatcat gatcgcggtc taacttggca gaataaccag gttctccctc
    52561 atgaagatcc gaatatccat tagcccaagc ttccttacag ctcgaaaaat ggatgttttc
    52621 ttccgccaaa actggttgtg aaaacaaggc taaaattggc aacgtcacca gactcatttt
    52681 taaaaataga cgtttattca tttctttctc ccataattat gatatcgatt tcaatattat
    52741 tttatcaaac ttatttcagc aattcaagga aacttctggt cttttctaca aactcctttg
    52801 gttttgcctt attcaagaca tgagggccat caggaatgat ctgaaactgc gaatctgtta
    52861 acagtctatg gagagctttc atagaactaa gattcggttt atctttgctg ccacaaatta
    52921 gtaaggttgg ataggagcaa gtccctgcta tatccgttaa atcaagtgtc ttcaattcct
    52981 cagaaactcc gaccataaga gtcttgtctg ctccctgttt ttcaaatact cttttgggaa
    53041 gtagtttaaa aatcagcaac tgaagataaa ataggatatt ccctgctaat ttaagcgggc
    53101 atcctgacag aatcaaagct cgaagatttg gtaaatcgta actggaaagt tctagtgtca
    53161 gggcagcacc taaggacaat ccaatcaaaa caaaaggttc tgtctcttga gctaggtgct
    53221 gataaactcg ctctttagct tgttgatagt tactaactcc agaaggaaat aactcgatag
    53281 cctcagaagg ataatctgtc agtagattcc gaacttcttt ccaagactct gctgactgcc
    53341 ctaacccatg caaaaatatc aatttcatct agttctcctc aaggcttagt tcatacaagc
    53401 ctctcactgc attacagccg taaatagctt ctgcttgggt taaatctgcc aaggtcaaga
    53461 ctttctcttc tacctgtcct gtttctagca aatactgacg gtaaattcct ggtaagattc
    53521 caagtcggat aggcggtgtg tagagttttc cagcgatttt cagaaccaaa tttcctatag
    53581 aggtttcaag cagttctcct gacttattgt ggtaaatctt ctcttgttct cctaggctca
    53641 aatgcggtcg gtgagtggtt ttaaagtagg taaaggattg attcaaagca gcttcctgaa
    53701 ggcagacttg ggcctgacaa aagcttgtac tgagaggggt taatacttga cgattgactt
    53761 ctatctctcc agatttgcta aggctgattc gcaagcggta atctcgatta gcttcacaat
    53821 cctgacactc ttcctcaatc ttgtgtccca agtcttctgc atcaaaagga aaagcaaaat
    53881 aacgactagc ttttctcagt ctttccagat gttgatcttc aaacagcagg ttcttctggc
    53941 tgatttcccc tgtcgtaatc agttggaagc gagcttgttt acgataaaga actgctgcct
    54001 tttgatgaac ctctcggtat tcagattccc atgtgctatc ccaagtaatc cctccgccaa
    54061 ctccataaat ggcttgacct ttgtgaagtt gaatggtacg aatggccaca ttaaaaatcc
    54121 gtcgtccatt tggaagcaag agaccaatcg ttccacagta gactccacgc ggttgaggct
    54181 ccaagtcctt gataatctcc attgtcgcaa ttttcggtgc acccgttatg gaaccacaag
    54241 gaaagagtga gcggaagatt tcaacaaggt ccacatcctc tcgcaactga ctcttgatgg
    54301 tcgaagtcat ctgccaaaca gttgaatact gctctacctg acacagacgc tccacgtgct
    54361 cgctcccaac ttcagaaata cggttcatat cattgcgcaa gaggtccaca atcatcatat
    54421 tttcagagcg atttttggga tcctgttcca accaactggc ctgttcaaga tcttcttggt
    54481 cagttacccc acgctgagtc gtccccttca ttggtcgtgt tgtcaactcg cgatcatttt
    54541 gctcaaaaaa gagctctggg ctcatggaaa tcactgccat ctcgtcatgt tccacatagg
    54601 cattgtagcc cgcctcctgc tctaccacca tacgattgta gatggcaaaa ggattggcac
    54661 ttaacttttg cttgagttgg acggtgtagt tgacctgata ggtgtctccc tgcctcaagt
    54721 gatggtgtat ctgggcaatg gccttttcat agtctgctgc agacgtcact tcctgccaat
    54781 ttgagggcaa atcaatatcc tcataagtca gaggaatagg ggaagtttct acgctatcat
    54841 gaacagtaaa gtaaagcagg tactctccca gtaggggatc cttgtgaact gctaattttt
    54901 cctcaaaagc aggtgcagcc tcgtagctga cataccccac cacataataa ccttgctctt
    54961 ggtagctttc cacttgtgcc agcaaatctg ccacttcttc tacatttctc gttttcaact
    55021 ctttaatagg ctgggcaaag gtatatctct cccctaaagt cctaaaatca atcactgttt
    55081 ttctatgcat accttaagta tagcataaaa aggcagatac agacaaagct gatctacctt
    55141 tttacgattt tattcattct atgcttgtgg tgcagtaaat agatcaccag agaaaccgtc
    55201 tgtgttttta aggagagctt taaagacttt cgatttcaag acaactgtat ttcggtattt
    55261 gtctttaata ctactatcgt ttagttccgt taaatcttta gtaacagcct catcaaacat
    55321 agtcttcaac tgttcatagg ttgaaatttg agtgccatta atttcaattg gtgcaaaacc
    55381 ttttttagat tttgtaagaa cttccccata ccattgcttc ttccaatctt caaggtttga
    55441 aaattggtta ttagaaactt tcttaataat gaaatcatca cctaatagac cgttattttc
    55501 tttattggct gcaccttgat gtttgcttga aacatagtca atgaacccat gttcatatcc
    55561 atagtaaccc cacatacgga aggcgttatg tttgaaggat agagaaccag gggcaccttg
    55621 actcgtatta ccgccataaa taccagccat catattaaca ttgacatatg ccgtaccaaa
    55681 gtcctctggg tggaagacct tattacctgg atttccgtga atggtcatga aattattatt
    55741 taccaagtca tcgatggttt caaggttagt tgttttctca gcgtctatca aatcacgcac
    55801 tttgtcccat tggtgaggac cacttagttt atttctgtcc attggtcgac gtgtttcgcg
    55861 atcaattttc ttgaaccact tactattgtc acctttaacc ttaggaagaa cagcctcagc
    55921 ttctgcataa tcgagcatca tcatagcttc attgtagttc ttcatgtaat ggtcgatttg
    55981 gtcacgtgtt tgaagtttgg taggatctgg attataccat tggtttccat catttgaacg
    56041 ttcaaatgcc atatttaatc caagtgcgcc atattcacct tgatgtccat gttctgctgg
    56101 agtttgtaac ataccttgag caaatgcttc aagatctgta ccctgtcgat gtctatgacc
    56161 tcccagatat gccattcggt catttacgtg ggtagtctca tgtgtaaagg cagatgtgcc
    56221 atattcactt attaaatccg acataacaaa atatacagca tccataggct gtggatcagc
    56281 aaagatgtaa gcatacgctc catacccata cttataatca tgatacttat caatacgtcc
    56341 aaagaattca cgaataggtg cataatccgg tttatctttt cgatgaccaa atctatcagg
    56401 ccaaccaccg ggtgcaccat gattatccca tacaggagtt ggaactacat tttgactctt
    56461 aagaagttta tcgcggacat tatcagtggc aaggcgtgac caaaaatcta agtaattaac
    56521 ttgctcttta gcacgtttat tgatttcact cttgaacgat tcacgttttt cttctgtatc
    56581 tttaccatac ttttcaaacg aactaaatga gatagtatta tatgttgaaa tcataaataa
    56641 atgtgcatct ttcaagttca gaagcgataa aatcatgcgt ccatgttgtc cgttattaag
    56701 tccttcatat agacgatatt ttttattagc aaatgcaggg ttagttgacg gttgttcaac
    56761 tacataagca ttattttcaa tagctttctt aaaccaaaca tttatgtctg tttcatttgt
    56821 gaatagtttc atattgtagg tcaagaagtc atgtaagttt ccagaaagag tatttttcgc
    56881 caccacttca cggaaggact cctgtgtacg acttccctta atatagtcct cttttgaacc
    56941 aatttctatt aatcgatcta aaacacttac attcttacca taaaaatctg gtttgaatag
    57001 cattaattct ttaatattga agttatcaaa tttcacaccg taataacgat ttaggtatgt
    57061 taatcctaac aggacagcag ctttgttatc ttcaattttc ttaatcaagg cacgttttgc
    57121 agcttcatct gtattcagtt gatgatcttc attttcaact aattttgtca caaatgtatt
    57181 aagatgatct tttacttctt taaagctttc ttctaagtaa agattcttaa ttgcattaac
    57241 tctgttatcc ccagttcttc ctaatcgttg ataaattgga tcagattgta attcaattgg
    57301 acttaaaata ccttcaatag cactaattaa atctgcacga tctttaacaa ccatatttgg
    57361 tgtatagacg acttcaccaa gctctgcgac actgtattct tttacttgct taacttgaga
    57421 gtctttagga gaaatcgtaa agatatcttt tgtcttatct gcgtaatgaa ccataatatg
    57481 gtcagcatct gtaaggtctg taataaagtc attacctttc attgcagtca cagacaatac
    57541 ttctttattc attaatggac tatcagttgt aagcttgttc ccttgattca caatccattc
    57601 tttgttgtag aacggttgga gtttttcaac attacgataa acaagctcac gatttgcatt
    57661 ataatcttga attgttttgt attcttcatc acgtaatata cggcgattca acttatcaac
    57721 caaatgctca gttacttcaa atgtatcagc agtgataccc atatccttaa ttttcttatc
    57781 agcttctacc tgtgaaattt ctttaatttt agacgattgt ttatgggttt tatctccaga
    57841 actcacaccg ataactgttg cattattagg tttaatccaa ttgcttacaa attcatcatc
    57901 catatcatta gaaccaaaga aaatatcacc acgcttaaca ttcactaagc tgatattgtt
    57961 atcaatggtt ccccaaggcc agtctttacc aattaaaccg cctacatcac ctctagcaac
    58021 atcaatagta cctttggcta cagaatttct tacattagac caagcaccaa catctcttgg
    58081 attaaaatca tgagctaaat gtcctactat agcacctgca cgagtattta aacctttaag
    58141 ttcaacatct gcataagctt tatttaaatt gcctcgataa atctcagatg caatcccagc
    58201 caagttccac cctttatcac caacagattg aacttttccg ataaaagcaa cattagtcat
    58261 aatacctgca tcatctaatt tatccaaaat acccgcaaca ttgttattac caacgatagt
    58321 acccgttact ttaatatttt caacagttgc atttttcact gtttgagcta atgaagctaa
    58381 ttgatttgcc caaggcatat taatattaac gttaattaaa ttaatatttt tgatagaacc
    58441 cccttcaact ctatcaaata atggacgagc agtgttatga atggagaaat gcttaccatc
    58501 aacacttgtt aagtgacctg taaatttacc tgttacatat gatttacttg gtgtaggtac
    58561 atttgttgca tttaaatccg atcctaattt aaactcaccg ttaggatttt tctgcatagc
    58621 atctactaaa tctttgaagt tatagtaaac gttattttgc gatgctttgg gtttctctat
    58681 gtaataagtg tatgtttgac tcaaactatt atttgaatca cgttggatta aatcaggagc
    58741 tgaagcagta actttaaata aggatgtctc ctcctcagtt acttcctcta tattagtaat
    58801 ggcaagcctt gttactttat tatgattagt ggtaattttt agataatatg acgttagatt
    58861 ttctggaaca gtttctagaa ggctactatc tgtttcattt ccattctcat ccactttcat
    58921 caatcttgtt tctttaatat ctttaatctc aactttttta aggtctaact gaacttcttt
    58981 atcttctaat atttcagttt cttcaccgtt acctcgatca tagaccatgg ttgtggatag
    59041 tgtataacct tgataatatt tcaagttgtc taaagtagct tgtaagttat tttcttctac
    59101 cgttacttct ttaacaactg ttccagtatt atcttttaga gctactttaa tcgatttaat
    59161 ttctactcca gctggtttag tcaatgtata actagctgtc gcactcttct tcaagacatc
    59221 tttatctgtt ttagcccatt ccaaggttgg tttctctaac tcttttgtgc cattcttaat
    59281 aattttgtct tgaggttttt caatcactgt ttctgtgata gtaggagcgt cacttgtttt
    59341 ttctccgcga attgttttat aggtttcagt aatttgtttc ttatcgttta caccttcttg
    59401 agttacttgt cttgttccgc gttttaaagt gtcatcttct tgttcttttg tttcaaaagg
    59461 aatgatttct tctcttgtct caaccgttgt cccttcaatt ggttttgtac cacggattac
    59521 ctgttgattt acaggctcct tggtgacttc cgtactggtt gaaagaactt ggtcagtttt
    59581 aacccctcct attgttttat aggttgtttt tgtaacttga cttccttttt caccatttcg
    59641 taggacagtt tcttcgtccg tgtacttggt tgggtcctca gtcgtttcag ttttatagtc
    59701 aagttctgta gttgattctt caacgagtgt tccttcagtc accttatact caggtaattg
    59761 ttctggaaca agagcctcac ccacgtaatc ttcttcttgc gtccccttag ctgttttagt
    59821 ctcctctttt ggttctacag tttcttcagc cttggtatct ggagttgact cttcttgttt
    59881 cggtgtctct tccgctcccc tatcttcttt aggattgtct tcttgtgatg attcttttgg
    59941 tgtacttggt tgctcagctt gtgtaggttg cacgggttgt tctgggactt ttgcttgttc
    60001 tactggtggt tcaacttttg attcctcagc tggtttgtct gatggttgac tttctggctt
    60061 aactgctact ttttcctctg attttgactc aacttctcca cctacttctt caactggagc
    60121 tggttctgct gaatcttctt tcccctcttc tactttagga agggtgtcgt cagtaggttt
    60181 tacctccgat tttggttctt cctttggact ttcttctgtt ctaggtgctt cttcttttgg
    60241 agtttcctct gtctctacta cttggttttc tgtcctagct tgctcctgat ttgttgttga
    60301 ttgaggagtc tcaacttcga ctacagtcac ctctccaggt tttgctgagg tttcttctaa
    60361 aacagtgtcc aagccaagcg ttttgaggat gtcacctgat agataaccaa catagcgata
    60421 gccatccatt tcaacaacac cctctcgact agccagcgct aaggtcgcaa ctgggtctac
    60481 agcccctgca ctaggaagaa ctaccaatcc catagctcca actagaaaga cgctagcaat
    60541 tttctttctc ttgtagatta aaagcaagct cccaacagtc agcaaaccaa aagctgtcaa
    60601 aacagatgct tctgtccctg tttgaggcaa ctgatctttt tgatacacca aaccatatac
    60661 aacttcattc ctgtcaggct ttcctgtctg aattaaatct ttagcttctt gtgaaataat
    60721 ctctttattt acatagtgat aggtagctgc gtccactaca gaaggagcca tcaaaaggct
    60781 tccaagaaat acagagccta caactccctt aatcttacga attgaaaaac ggtctttttt
    60841 aaacactttc atctccttta ttcattctca agactttcta atagcatctt gcggatagtg
    60901 cgcacgcgca cctccgatta attttggacg actagccagt gccgttacat gggcatgacc
    60961 aatctctctc aaaatagggc gaatcggaac ctgaacatgc ttgacatgca tgccaattgc
    61021 agtgtctccg atatccaatc cagcatgagc cttgataaat tcaacctcaa ctggatcctg
    61081 cataaactta aaggctgcca actgccccga acctcctgca tgaagagtag gatggacact
    61141 gacaatttcc agatcaaact gctctgccac ctgacgttca acaacgagag cccgattgac
    61201 atgctcacaa ccttgaactg ctaaatggat acctctacta cctagaatac ccaagatagt
    61261 ctccactatc agctcaccaa tctcttgact ggattctttc ccaatctgac cacctagcac
    61321 ctcactagaa gatagaccta aaacaaaaag gaccccctgc ttcaaattgg tcttttctaa
    61381 aacatcttcc actacctgac gtgtttctct ttgaatctgt gtctcgttca tctctgttac
    61441 ctctgttgtc actcttctat cataccgttt tttcttgttt ttagcaagat agacaaccta
    61501 taaagtctgc ccaattacgc ataaaactcc cagaattgac tgggagttag ctagtttcta
    61561 ttctatttat atatatttca actttcgttc ctttttgggg tctagaatca atcttcatct
    61621 ggtaattggc tccaaaatga agtttgagcc gttgatcgac attttgaaga ccaactcccc
    61681 cacgtttgag ttgactttga ctactatcac cagcatcttg gaagccaacg ccatcatcct
    61741 caatacggat gaccaatccc gaatcctgtt tctggacaga aagtttaata tggccctgac
    61801 cttccttttc cttaatgcca tggtaaagag cattttctac aaggggttgt aggaccagct
    61861 tgggtaagac taaattatca aaggcaacat tttcattaat ttcgtattcc agcttatctc
    61921 catagcgttg tttctggata aagagatact ggcggacatg attgatttcg tcagagagac
    61981 aaatcaagtc cttgccttga ttgagcgcca agcggaaata ggttgccaag gacttggtca
    62041 cctgcaccac tcgctgacta tcatgaaatt cagccatcca gatgatggtg tccaaagtgt
    62101 tatagaggaa atgtggatta atctggctcg aaagggcttg aagttggtac tgacgggtcg
    62161 tttcttcctg gctacgaata gctaccatca actgatcaat ctgatccaac atagcattaa
    62221 attggcgagt tacttctctc agttcatagg caccaacttc cttggcacga agattttgag
    62281 caccagaagc aatttccaac atggtttctc tcaaatcctt caaaggagca atccagcgtt
    62341 taagactgaa ccacactaag cagagacaaa caagaagaga tgtgacactg gccccaagca
    62401 aggtccacaa gagctgactc cgaacctggt ctaacttttc caatgatgac acgccaagta
    62461 ccgtccaatc agttcctgca atcttctctt gactgacgta ggatttgtga ccaggagtat
    62521 aaccctgacc tgtctcgatg tagggtttca tagcctccat tttgctagac gaactataaa
    62581 ctgtgtgttg aggatggtag acaaattcat ggttttcatt gataatgaag gcaaagccct
    62641 gctgccccaa ctggagttga ttgagatagg cttccagagt ttcataagaa atatccaaac
    62701 gaagcacacc aagattggct ccctttgcat caacaagttc ttgagtgaca gaaatgaccc
    62761 actgactatc tgatttacga gctggagtca aaacaggcat agctccctga tgaatagcct
    62821 tttggtacca atcctcagcc atcatatcag aggaagtttt catctgcaca ctgtcatctg
    62881 tagaaatgac ctgaccagat ttggtcacca gcacaacagt tttcaagtcc ttatctgact
    62941 tcaagatggt caaaaacaaa tctcggattc cctcgacctt gtcttgactg ggattctcag
    63001 cataggccag aacatccgtc tgctgggtca aaccagtcga ggtggtttct agttttttga
    63061 tataagactg aataaagtgg ctagtctggc tgatggtcgt ttggctgttg ccctcaatgg
    63121 tggcctcaat ggctgaagaa cttgattgat agtagaaagt tccaaccaga gctaggagaa
    63181 tgagaaagac cagaaagatg gaaataacca ttctaactaa aagagaagaa cgcttcatcg
    63241 gtcttctccc ttcttaaact gacgaggtgt cacacctgca atctgcttaa aacgttgggt
    63301 aaaatagttc atatcttcaa aaccaacctt ctctgcgatc tcataaatct tcagatctgt
    63361 agttaaaagc aagagcttgg cttgtttaac acgttctctc accagataat cctgaaaagg
    63421 caagcccaac tctttcttaa tcaaggaact cagataggtc ggactaaaac ctaagtcact
    63481 ggctaaagac tttaaactaa attggctatc agccagatga gactggattt tctgggccat
    63541 gtttccttca aacctattag tcaataaatc ttgtaactgc tcttctttct cttccttgtc
    63601 tagtttttgt ttgattttcc ccaacatttc ctcaatatcc tgacgagaaa agggtttgag
    63661 caggtagtcg tccacaccta gtttgacagc agacaaggca taatcaaaat catcgtaacc
    63721 tgttaaaaag accaaatgaa cctgaggata ggtttctcgt accagactgg ccaactggat
    63781 gccatttaga tgaggcatgt tgatatcggt taaaatgata tctggcacct gcttttggat
    63841 caattcccaa gcctgccttc cattttcagc ctgaccgatg atttccatat cgtaggctgc
    63901 tacattgacc agtttagtca aaccttgtct taccagatat tcatcttcta cgattaagat
    63961 tgtgtaggtc atgctctgct cctttaccac ttactagtat cagtatagca aaattctcct
    64021 ctaactgctt aggaaagacc tcttatactc aataaaaatc aaaaagtaaa ctaggaagat
    64081 agccacaggt ttctcaaagt atagctttga ggttgtaaat aaaactgacg aagtcagctc
    64141 aaagtatagc tttgaggttg ta
//
LOCUS       DAVBEO010000006        51676 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 009
            SAMEA1678075-rid20185393.denovo.006, whole genome shotgun sequence.
ACCESSION   DAVBEO010000006 DAVBEO010000000
VERSION     DAVBEO010000006.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678075
            Sequence Read Archive: ERR226392
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 51676)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 51676)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980207.1
            Genome Coverage       :: 150x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:50:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 72 of 147
            Pseudo Genes (incomplete)         :: 72 of 147
            Pseudo Genes (internal stop)      :: 42 of 147
            Pseudo Genes (multiple problems)  :: 32 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..51676
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678075-rid20185393.denovo.006"
                     /strain="KS 009"
                     /db_xref="taxon:1313"
     gene            complement(54..362)
                     /locus_tag="VQ543_000409"
                     /pseudo
     CDS             complement(54..362)
                     /locus_tag="VQ543_000409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000996568.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GDP-mannose 4,6-dehydratase"
     gene            complement(604..900)
                     /locus_tag="VQ543_000410"
     CDS             complement(604..900)
                     /locus_tag="VQ543_000410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000239014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2611194.1"
                     /translation="MVKINKICSIQGSSVENEDIVGSQNQYFWIIGGATDLYNSKEEI
                     GYSVSEVVHILSESLSVNCKESKTLKQIFETALLEVKDEIGLNSYELTEYSKMK"
     gene            complement(884..3043)
                     /gene="pfbA"
                     /locus_tag="VQ543_000411"
     CDS             complement(884..3043)
                     /gene="pfbA"
                     /locus_tag="VQ543_000411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multi-ligand-binding adhesin PfbA"
                     /protein_id="HET2611195.1"
                     /translation="MLKIVKKLEVLMKYFVPNEVFSIRKLKVGTCSVLLAISILGSQG
                     ILSDEVVTSSSPMATKESSNAITNDLDNSPTVNQNRSAEMIASNSTTNGLDNSLSVNS
                     ISSNGTIRSNSQLDNRTVESTVISTNENKSYKEDVISDRIIKKEFEDTALSVKDYGAV
                     GDGIHDDRQAIQDAIDAAAQGLGGGNVYFPEGTYLVKEIVFLKSHTHLELNEKATILN
                     GINIKNHPSIVFMTGLFTDDGAQVEWGPTEDISYSGGTIDMNGALNEEGTKAKNLPLI
                     NSSGAFAIGNSNNVTIKNVTFKDSYQGHAIQIAGSKNVLVDNSRFLGQALPKTMKDGQ
                     IISKESIQIEPLTRKGFPYALNDDGKKSENVTIQNSYFGKSDKSGELVTAIGTHYQTL
                     STQNPSNIKILNNHFDNMMYAGVRFTGFTDVLIKGNRFDKKVKGESVHYRESGAALVN
                     AYSYKNTKDLLDLNKQVVIAENIFNIADPKTKAIRVAKDSAEYLGKVSDITVTKNVIN
                     NNSKETEQPNIELLRVSDNLVVSENSIFGGKEGIVIEDSKGKITVLNNQFYNLSGKYI
                     SFIKSNANGKESVIRDSDGNFNIVTENGLYKIVTNNLSDKNEKEKNKEEKQSNSNNVI
                     DSNQKNGEFNSSKDNRQMNDKIDNKQDNKTEEVNYKIVGDGRETENHINKSKEIVDVK
                     QKLPKTGSNKIMELFLTVTGIGLLLTLKGLKYYGKDK"
     gene            complement(4173..5399)
                     /locus_tag="VQ543_000412"
     CDS             complement(4173..5399)
                     /locus_tag="VQ543_000412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001134527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegT/DnrJ/EryC1/StrS aminotransferase family
                     protein"
                     /protein_id="HET2611196.1"
                     /translation="MPNYNIPFSPPDITEAEIAEVADTLRSGWITTGPKTKELERRLS
                     LYTQTPKTVCLNSATAALELILRVFEVGPGDEVIVPAITYTASCSVITHVGATPVMVD
                     IQADTFEMDYDLLEQAITEKTKVIIPVELAGIVCDYDRLFQVVEKKRDFFTASSKWQK
                     AFNRIVIVSDSAHALGSTYKGQPSGSIADFTSFSFHAVKNFTTAEGGSATWKANPVID
                     DEEMYKEFQILSLHGQTKDALAKMQLGSWEYDIVTPAYKCNMTDIMASLGLVQLDRYP
                     SLLQRRKDIVDRYDSGFAGSRIHPLAHKTETVESSRHLYITRVEGASLEERNLIIQEL
                     AKAGIASNVHYKPLPLLTAYKNLGFDMTNYPKAYAFFENEITLPLHTKLSDEEVDYII
                     ETFKTVSEKVLTLSKK"
     gene            complement(5442..6134)
                     /locus_tag="VQ543_000413"
     CDS             complement(5442..6134)
                     /locus_tag="VQ543_000413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000922225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HET2611197.1"
                     /translation="MLKWEDLPVEMKSSEVESYYQLVSKRKGSLIFKRCLDWVLALVL
                     LVLTSPIFLILSIWIKLDSKGPVIYKQERVTQYNRRFKIWKFRTMVTDADKKGNLVTS
                     ANDSRITKVGNFIRRVRLDELPQLVNVLKGEMSFVGTRPEVPRYTEQYSTEMMATLLL
                     QAGITSPASINYKDEDTIISQMTEKGLSVDQAYVEHVLPEKMRYNLAYLREFSFFGDI
                     KIMFQTVFKVLK"
     gene            complement(6320..8071)
                     /locus_tag="VQ543_000414"
     CDS             complement(6320..8071)
                     /locus_tag="VQ543_000414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2611198.1"
                     /translation="MQNKQEQWAVLKRLMSYLKPYRLLTFLALSFLLATTVIKSVIPL
                     VASHFIDQYLSNLNQLAVTVLLVYYGLYILQTVVQYVGNLLFARVSYSIVRDIRRDAF
                     ANMEKLGMSYFDKTPAGSIVSRLTNDTETISDMFSGILSSFISAVFIFLTTLYTMLVL
                     DFRLTALVLLFLPLIFLLVNLYRKKSVKIIEKTRSLLSDINSKLAENIEGIRIIQAFN
                     QEKRLQAEFDEINQEHLVYANRSVALDALFLRPAMSLLKLLGYAVLMAYFGYRGLSIG
                     ITAGTMYAFIQYINRLFDPLIEVTQNFSTLQTSMVSAGRVFALVDERTYEPLQENGQA
                     KVQEGNIRFEHVCFSYDGKHPILDDISFSVNKGETIAFVGHTGSGKSSIINVLMRFYE
                     FQSGRVLLDDVDIRDFSQEELRKNIGLVLQEPFLYHGTIKSNIAMYQEISDEQVQAAA
                     AFVDADSFIQELPQGYDSPVSERGSSFSTGQRQLLAFARTVASQPKILILDEATANID
                     SETESLVQASLAKMRQGRTTIAIAHRLSTIQDANCIYVLDKGRIIESGTHEELLALGG
                     TYHKMYSLQAGAMAYTL"
     gene            complement(8061..9806)
                     /locus_tag="VQ543_000415"
     CDS             complement(8061..9806)
                     /locus_tag="VQ543_000415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HET2611199.1"
                     /translation="MSIIQKLWWFFKLEKHRYLVGIVALVLVSVLNLIPPMVMGRVID
                     AITSGQLTQQDLLLSLFYLLLAAFGMYYLRYVWRMYILGTSYCLGQIMRSRLFKHFTK
                     MSPAFYQTYRTGDLMAHATNDINALTRLAGGGVMSAVDASITALVTLLTMLFSISWQM
                     TLVAILPLPFMAYATSRLGRKTHKAFGESQAAFSELNNKVQESVSGIKVTKSFGYQAD
                     ELKSFQAVNELTFQKNLQTMKYDSLFDPMVLLFVGSSYVLTLLVGSLMVQEGQITVGN
                     LVTFISYLDMLVWPLMAIGFLFNTTQRGKVSYQRIENLLSQESPVQDPEFPLDGIENG
                     RLEYAIDSFAFENEETLTDIHFSLAKGQTLGLVGQTGSGKTSLIKLLLREYDVDKGAI
                     YLNGHDIRDYRLTELRSLMGYVPQDQFLFATSILDNIRFGNPNLPLSEVEEATKLARV
                     YQDIVDMPQGFDTLIGEKGVSLSGGQKQRLAMSRAMILNPDILILDDSLSAVDAKTEY
                     AIIDNLKETRKDKTTIITAHRLSAVVHADFILVLQNGQIIERGRHEDLLAMDGWYAQT
                     YQSQQLEMKGEEDAE"
     gene            complement(10012..10308)
                     /locus_tag="VQ543_000416"
     CDS             complement(10012..10308)
                     /locus_tag="VQ543_000416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001276342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF421 domain-containing protein"
                     /protein_id="HET2611200.1"
                     /translation="MSASDVALKLRSQGIFQMKQVKRAVQEQNGQLIVVQMGDENPKY
                     PVVTDGVIQVDVLESIGRSEEWLLDNLSKQGHDNVANIFIAEYDKGAVTVVTYE"
     gene            complement(10461..10917)
                     /locus_tag="VQ543_000417"
                     /pseudo
     CDS             complement(10461..10917)
                     /locus_tag="VQ543_000417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730499.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3290 family protein"
     gene            11051..11878
                     /gene="xth"
                     /locus_tag="VQ543_000418"
     CDS             11051..11878
                     /gene="xth"
                     /locus_tag="VQ543_000418"
                     /EC_number="3.1.11.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006596696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease III"
                     /protein_id="HET2611201.1"
                     /translation="MKLISWNIDSLNAALTSDSARAKLSQEVLQTLVAENADIIAIQE
                     TKLSAKGPTKKHVEILEELFPGYENTWRSSQEPARKGYAGTMFLYKKELTPTISFPEI
                     GAPSTMDLEGRIITLEFDAFFVTQVYTPNAGDGLKRLEERQVWDVKYAEYLAELDKEK
                     PVLATGDYNVAHNEIDLANPASNRRSPGFTDEERAGFTNLLATGFTDTFRHVHGDVPE
                     RYTWWAQRSKTSKINNTGWRIDYWLTSNRIADKVTKSDMIDSGARQDHTPIVLEIDL"
     gene            11890..12033
                     /locus_tag="VQ543_000419"
     CDS             11890..12033
                     /locus_tag="VQ543_000419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase"
                     /protein_id="HET2611202.1"
                     /translation="MDYNAVIPEFLVSNIEQSRSFYCGLLGFRIEYQRSEENFLFLLK
                     SVN"
     gene            12033..12272
                     /locus_tag="VQ543_000420"
     CDS             12033..12272
                     /locus_tag="VQ543_000420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase"
                     /protein_id="HET2611203.1"
                     /translation="MLEEGTKDQLAELTYPFGRGVNLSFGIKDVPKLYQKVMEANYPI
                     YRPLTKRKFRVSDPYIYPHKFAVLDPDGYFLRFSE"
     regulatory      12656..12751
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            13151..13732
                     /locus_tag="VQ543_000421"
     CDS             13151..13732
                     /locus_tag="VQ543_000421"
                     /EC_number="2.4.2.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000770427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine phosphoribosyltransferase"
                     /protein_id="HET2611204.1"
                     /translation="MKLLEERILKDGHILGDNILKVDSFLTHQVDFSLMREIGKVFAE
                     KFAAAGITKVVTIEASGIAPAVFTAEALNVPMIFAKKAKNITMNEGILTAQVYSFTKQ
                     VTSTVSIAGKFLSPEDKVLIIDDFLANGQAAKGLIQIIEQAGATVQAIGIVIEKSFQD
                     GRDLLEKAGYPVLSLARLDRFENGQVVFKEADL"
     gene            13732..14994
                     /locus_tag="VQ543_000422"
     CDS             13732..14994
                     /locus_tag="VQ543_000422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001194492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine permease"
                     /protein_id="HET2611205.1"
                     /translation="MQTQEKHSQAAVLGLQHLLAMYSGSILVPIMIATALGYSAEQLT
                     YLISTDIFMCGVATFLQLQLNKYFGIGLPVVLGVAFQSVAPLIMIGQSHGSGAMFGAL
                     IASGIYVVLVSGIFSKVANLFPSIVTGSVITTIGLTLIPVAIGNMGNNVPEPTGQSLL
                     LSAITVLIILLINIFTKGFIKSISILIGLVVGTAIAATMGLVDFSPVAVAPLVHVPTP
                     LYFGMPTFEISSIVMMCIIATVSMVESTGVYLALSDITKDPIDSTRLRNGYRAEGLAV
                     LLGGIFNTFPYTGFSQNVGLVKLSGIKKRLPIYYAAGFLVLLGLLPKFGALAQIIPSS
                     VLGGAMLVMFGFVSIQGMQILARVDFANNEHNFLIAAVSIAAGVGLNNSNLFVSMPTA
                     FQMFFSNGIVVASLLAIVLNAVLNHKKK"
     gene            complement(15081..15947)
                     /locus_tag="VQ543_000423"
     CDS             complement(15081..15947)
                     /locus_tag="VQ543_000423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000815109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II restriction endonuclease"
                     /protein_id="HET2611206.1"
                     /translation="MKQTRNFDEWLSTMTDTVADWTYYTDFPKVYKNVSSIKVALNIM
                     NSLIGSKNIQEDFLDLYQNYPEILKVVPLLIAKRLRDTIIVKDPIKDFYFDFSKRNYS
                     IEEYTMFLEKSGIFDLLQNHLVSNLVDYVTGVEVGMDTNGRKNRTGDAMENIVQSYLE
                     AEGYILGENLFKEIEQNEIEEIFSVDLSAITNDGNTVKRFDFVIKNEQVLYLIEVNFY
                     SGSGSKLNETARSYKMIAEEIKAIPNVEFMWITDGQGWYKAKNNLRETFDILPFLYNI
                     NDLEHNILKNLK"
     gene            complement(15934..16704)
                     /locus_tag="VQ543_000424"
     CDS             complement(15934..16704)
                     /locus_tag="VQ543_000424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific DNA-methyltransferase"
                     /protein_id="HET2611207.1"
                     /translation="MTKPYYNKNKMILVHSDTFKFLSKMKPESMDMIFADPPYFLSNG
                     GISNSGGQVVSVDKGDWDKISSFEEKHEFNRKWIRLAKEVLKPNGTVWISGSLHNIYS
                     VGMALEQEGFKILNNITWQKTNPAPNLSCRYFTHSTETILWARKNDKKARHYYNYDLM
                     KELNDGKQMKDVWTGSLTKKVEKWAGKHPTQKPEYLLERIILASTKEGDYILDPFVGS
                     GTTGVVAKRLGRRFIGIDAEKEYLKIARKRLEAENETN"
     gene            complement(16730..17584)
                     /locus_tag="VQ543_000425"
     CDS             complement(16730..17584)
                     /locus_tag="VQ543_000425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012972462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA adenine methylase"
                     /protein_id="HET2611208.1"
                     /translation="MKIKEIKKVTLQPFTKWTGGKRQLLPVIRELMPKTYNRYFEPFV
                     GGGALFFDLAPKDAVINDFNAELINCYQQIKDNPQELIEILKVHQEYNSKEYYLDLRS
                     ADRDERIDMMSEVQRAARILYMLRVNFNGLYRVNSKNQFNVPYGRYKNPKIVDEELIS
                     AISVYLNNNQLEIKVGDFEKAIVDVRTGDFVYFDPPYIPLSETSAFTSYTHEGFSFAD
                     QVRLRDAFKRLSDTGAYVMLSNSSSALVEELYKDFNIHYVEATRTNGAKSSSRGKISE
                     IIVTNYEK"
     gene            complement(17741..18145)
                     /locus_tag="VQ543_000426"
     CDS             complement(17741..18145)
                     /locus_tag="VQ543_000426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000651202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PaaI family thioesterase"
                     /protein_id="HET2611209.1"
                     /translation="MKDFHFDAISAFENYEIEKMRDGHVVVTTKVVNSSLNYYGNAHG
                     GYLFTLCDQISGLVVISLGLDGVTLQSSINYLKAGKLDDVLTIKGECVHQGRTTCVMD
                     VDITNQEGRNVCKATFTMFVTGQRSEERRVRI"
     gene            complement(18215..19696)
                     /locus_tag="VQ543_000427"
     CDS             complement(18215..19696)
                     /locus_tag="VQ543_000427"
                     /EC_number="2.7.7.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose--hexose-1-phosphate
                     uridylyltransferase"
                     /protein_id="HET2611210.1"
                     /translation="MTLVDKFVTHVISESSFEEMDRIYLTNRVLARVGEGVLEVETNL
                     DKLIDLKDQLVEEAVRLETIEDSQTAREILGTELMDLVTPCPSQVNRDFWEAYAYSPE
                     QAIEDFYQLSQKNDYIKLKAIAKNIVYRVPSDYGELEITINLSKPEKDPKEIAVAKLV
                     QASNYPQCQLCLENEGYHGRVNHPARSNHRIIRFEMVGQEWGFQYSPYAYFNEHCIFL
                     DGQHRPMAISRQSFERLLAIVEQFPGYFAGSNADLPIVGGSILTHDHYQGGRHVFPME
                     LAPLQKTFRFAGFEQVKAGIIKWPMSVLRLTSDSKEDLINLADKIFQEWRQYSDSSVQ
                     ILAETDGTPHHTITPIARKRDGQFELDLVLRDNQTSADHPDGIYHPHKDVQHIKKENI
                     GLIEVMGLAILPPRLKEEVEQVASYLVGEAVTVADYHQEWADQLKSQHPDLTDKEKAL
                     AIVKDSVGAIFARVLEDAGVYKQTEQGQTAFMRFVEHVGILLD"
     gene            complement(19715..20893)
                     /locus_tag="VQ543_000428"
     CDS             complement(19715..20893)
                     /locus_tag="VQ543_000428"
                     /EC_number="2.7.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactokinase"
                     /protein_id="HET2611211.1"
                     /translation="MAQHLTTEALRKDFLAVFGQEADQTFFSPGRINLIGEHTDYNGG
                     HVFPAAISLGTYGAARKRDDQVLRFYSANFEDKGIIEVPLADLKFEKEHNWTNYPKGV
                     LHFLQEAGHVIDKGFDFYVYGNIPNGAGLSSSASLELLTGVVAEHLFDLKLERLDLVK
                     IGKQTENNFIGVNSGIMDQFAIGMGADQRAIYLDTNTLEYDLVPLDLKDNVVVIMNTN
                     KRRELADSKYNERRAECEKAVEELQVALDIQTLGELDEWAVDQYSYLIKDENRLKRAR
                     HAVFENQRTLKAQAALQAGDLETFGRLMNASHVSLEHDYEVTGLELDTLVHTAWAQEG
                     VLGARMTGAGFGGCAIALVQKDTVEAFKEAVGKHYEEVVGYAPSFYIAEVAGGTRVLD
                     "
     gene            21058..22065
                     /gene="galR"
                     /locus_tag="VQ543_000429"
     CDS             21058..22065
                     /gene="galR"
                     /locus_tag="VQ543_000429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000212522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator GalR"
                     /protein_id="HET2611212.1"
                     /translation="MATLKDIAQLASVSIATVSRVLNRDQSLSVTEETRHRILTVAEE
                     LGYTKHLKTGESHKPKQKIAIIQWVSEQGELDDLYYYQIRLGIEKRAQELDYDILRYF
                     NDHPFTLSEEVIGILCIGKFSRAQISAFEEYQKPLVFLDSDTLSLGHTCIITDFYTAM
                     KQVVDYFLSQGMDRIGILTGLEETTDQEEIIQDKRLENFRNYSQAKGIYHDELVFQGN
                     FTAQSGYDLMKEAIQNLGDQLPPAFFAASDSLAIGALRALQEAGISLPDRVSLISFND
                     TSLTKQVYPPLSSITVYTEEMGRAGMDILNKEVLHDRKIPSLTMLGTRLTLRESTLNQ
                     E"
     gene            complement(22111..23148)
                     /locus_tag="VQ543_000430"
     CDS             complement(22111..23148)
                     /locus_tag="VQ543_000430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000833740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase catalytic
                     domain-containing protein"
                     /protein_id="HET2611213.1"
                     /translation="MKSAVYTKAGQVGLASIERPQIIEADDVIIRVVRACVCGSDLWR
                     YRNPETKAGHKNSGHEAIGIVEEAVEAITTVKPGDFVIVPFTHGCGECDACLAGFDGS
                     CDNHIGNNLGGDFQAEYIRFHYANWALVKIPGQPSDYTEGMLQSLLTLADVMPTGYHA
                     ARVANVQKGDKVVVIGDGAVGQCAVIAAKMRGASQIILMSRHEDRQKMAMESGATAVV
                     AERGQEGITKVREILGGGADAALECVGTEAAIEQALGVLHNGGRMGFVGVPHYNNRAL
                     GSTFMQNISVAGGAASATTYDKQFLLKAVLDGDINPGRVFTSSYKLEDIDQAYKDMDE
                     RKTIKSMIVIE"
     gene            complement(23149..23502)
                     /locus_tag="VQ543_000431"
     CDS             complement(23149..23502)
                     /locus_tag="VQ543_000431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HET2611214.1"
                     /translation="MNIKSASDLLGISADTIRYYERVGLVPPITRTATGIRDFQDQDI
                     EALEFIKCFRSAGVSVDSLVDYMSLYQKGDETREERLGILEEEKQKLEERLSQLQTAL
                     NRLNLKIKLYKEGKF"
     gene            complement(23746..24636)
                     /locus_tag="VQ543_000432"
     CDS             complement(23746..24636)
                     /locus_tag="VQ543_000432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000645104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HET2611215.1"
                     /translation="MKAKYAVWVAFFLNLTYAIVEFIAGGVFGSSAVLADSVHDLGDA
                     IAIGISAFLETISNREEDNQYTLGYKRFSLLGALVTAVILVTGSVLVILENVTKILHP
                     QPVNDEGILWLGIIAITINLLASLVVGKGKTKNESILSLHFLEDTLGWVAVILMAIVL
                     RFTDWYILDPLLSLVISFFILSKALPRFWSTLKIFLDAVPEGLDIKQVKSGLERLDNV
                     ASLNQLNLWTMDALEKNAIVHVCLKEMEHMETCKESIRIFLKDCGFQNITIEIDADLE
                     THQTHKRKVCDLERSYEHQH"
     gene            24769..25305
                     /locus_tag="VQ543_000433"
     CDS             24769..25305
                     /locus_tag="VQ543_000433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HET2611216.1"
                     /translation="MTNIDRRISKTKKAIYQAFIQLLNAKGYEATTVQDIIDLADVGR
                     STFYCHYESKELLLDQLCRYLFHHLFEREQAISTEDYLAHLFLHFHKNQDHITSLLFS
                     KNDYFLRQLHKELEHHVYSVLADNLKEAHPNLPTSYLQHLVMSNFIETLTWWLKKGQD
                     FTDQEVVQFYLDLLIPKN"
     gene            complement(25472..26278)
                     /locus_tag="VQ543_000434"
     CDS             complement(25472..26278)
                     /locus_tag="VQ543_000434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide riboside transporter PnuC"
                     /protein_id="HET2611217.1"
                     /translation="MHTYLQKKIENIKTTLGEMSGGYRRMVAAMADLGFSGTMKAIWD
                     DLFAHRSFAQWIYLLVLGSFPLWLELVYEHRIVDWIGMICSLTGIICVIFVSEGRASN
                     YLFGLINSVIYLILALQKGFYGEVLTTLYFTVMQPIGLLVWIYQAQFKKEKQEFVARK
                     LDGKGWTKYLSISVLWWLAFGFIYQSIGANRPYRDSITDATNGVGQILMTAVYREQWI
                     FWAATNVFSIYLWWGESLQIQGKYLIYLINSLVGWYQWSKAAKQNTDLLN"
     gene            complement(26623..28143)
                     /locus_tag="VQ543_000435"
     CDS             complement(26623..28143)
                     /locus_tag="VQ543_000435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate-binding
                     protein"
                     /protein_id="HET2611218.1"
                     /translation="MTNLIATFQDRFSDWLTALSQHLQLSLLTLLLAILLAIPLAVFL
                     RYHEKLADWVLQIAGIFQTIPSLALLGLFIPLMGIGTLPALTALVIYAIFPILQNTIT
                     GLKGIDPNLQEAGIAFGMTRWERLKKFEIPLAMPVIMSGIRTAAVLIIGTATLAALIG
                     AGGLGSFILLGIDRNNASLILIGALSSAVLAIAFNFLLKVMEKAKLRTIFSGFALVAL
                     LLGLSYSPALLVQKEKENLVIAGKIGPEPEILANMYKLLIEENTSMTATVKPNFGKTS
                     FLYEALKKGDIDIYPEFTGTVTESLLQPSPKVSHEPEQVYQVARDGIAKQDHLAYLKP
                     MSYQNTYAVAVPKKIAQEYGLKTISDLKKVEGQLKAGFTLEFNDREDGNKGLQSMYGL
                     NLNVATMEPALRYQAIQSGDIQITDAYSTDAELERYDLQVLEDDKQLFPPYQGAPLMK
                     EALLKKHPELERVLNTLAGKITESQMSQLNYQVGVEGKSAKQVAKEFLQEQGLLKK"
     gene            complement(28136..28864)
                     /locus_tag="VQ543_000436"
     CDS             complement(28136..28864)
                     /locus_tag="VQ543_000436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2611219.1"
                     /translation="MIEYKNVALRYTEKDVLRDVNLQIEDGEFMVLVGPSGSGKTTML
                     KMINRLLEPTDGNIYMDGKRIKDYDERELRLSTGYVLQAIALFPNLTVAENIALIPEM
                     KGWSKEEITKKTEELLAKVGLPVAEYGHRLPSELSGGEQQRVGIVRAMIGQPKIFLMD
                     EPFSALDAISRKQLQVLTKELHKEFGMTTIFVTHDTDEALKLADRIAVLQDGEIRQVA
                     NPETILKAPATDFVADLFGGSVHD"
     gene            complement(28879..29643)
                     /locus_tag="VQ543_000437"
     CDS             complement(28879..29643)
                     /locus_tag="VQ543_000437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000043863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nuclear transport factor 2 family protein"
                     /protein_id="HET2611220.1"
                     /translation="MSQQVKNAHNLYIHAIQDGRVAEAQAQSVGDTYIQHSTGVPDGK
                     EGFAAFFADFFERHPERQIKIVRTIEDGNLVFVHVHQYLNGGEAQWVTTDTFRADENG
                     RIVEHWDVVDYYRTPENDQLDQIFGDFEIKDLDKKAENKKLVRRFLTEIFQNGELEQW
                     SDYVADDLIQHNHDIGQGSAAYKNYVAEYSVTFDFVFQLLGQGNYVVSYGQTQIDGVA
                     YAQYDIFRLENGKIVEHWDNKEVMPKVEDLTNRGKF"
     gene            complement(29647..30090)
                     /locus_tag="VQ543_000438"
     CDS             complement(29647..30090)
                     /locus_tag="VQ543_000438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000655204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HET2611221.1"
                     /translation="MKDSHLLAHHIRLLNGRIFQKLLSQDPEALYRGEQGKILAVLWN
                     SETGCATATDIALATGLANNTLTTMIKKLEEQKLVIVSPCGKDKRKKYLVLTELGKFQ
                     KEVGHRVSQKLDTIFYKGFSEEEIHQFEGFQERILANLKEKGNEV"
     gene            complement(30772..31068)
                     /locus_tag="VQ543_000439"
     CDS             complement(30772..31068)
                     /locus_tag="VQ543_000439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000230158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HET2611222.1"
                     /translation="MAEPNLESLIKDLYNHARHDLSEDLVAALLETAKKLPTTNEQLQ
                     AVRLSGLVNRELLLNPKHPAPELLNLARFIKREEAKYRGTATSALMYEELFKML"
     gene            complement(31090..32154)
                     /gene="pepA"
                     /locus_tag="VQ543_000440"
     CDS             complement(31090..32154)
                     /gene="pepA"
                     /locus_tag="VQ543_000440"
                     /EC_number="3.4.11.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamyl aminopeptidase"
                     /protein_id="HET2611223.1"
                     /translation="MTTLFSKIKEVTELAAVSGHEAPVRAYLREKLTPHVDEVVTDGL
                     GGIFGIKHSEAVDAPRVLVASHMDEVGFMVSEIKPDGTFRVVEIGGWNPMVVSSQRFK
                     LLTRDGHEIPVISGSVPPHLTRGKGGPTMPAIADIVFDGGFADKAEAESFGIRPGDTI
                     VPDSSAILTANEKNIISKAWDNRYGVLMVSELAEALSGQKLGNELYLGSNVQEEVGLR
                     GAHTSTTKFDPEVFLAVDCSPAGDVYGGQGKIGDGTLIRFYDPGHLLLPGMKDFLLTT
                     AEEAGIKYQYYCGKGGTDAGAAHLKNGGVPSTTIGVCARYIHSHQTLYAMDDFLEAQA
                     FLQALVKKLDRSTVDLIKHY"
     gene            32555..33256
                     /gene="galE"
                     /locus_tag="VQ543_000441"
     CDS             32555..33256
                     /gene="galE"
                     /locus_tag="VQ543_000441"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HET2611224.1"
                     /translation="MTKTILVTGGTSYIGSHTVKALLNAGYKVHVLDNLSTGNRAAVD
                     SRASFKELDVYDASALKAYLEENQIDAVLHCAGEIVVSESIENPSKYFTANVAGMNQV
                     LKVLSEVGIQKIMFSSTASLYGNNCIDKPVTEDTLLDPVNPYAETKLMGERMIYWMAN
                     RYDWKYVIFRYFNVAGAEMDASNGLRVKNPTHIIPNINKTALGQNDSLKIFGDDYDTR
                     DGSCIRDYIYVLDLA"
     gene            33679..34638
                     /locus_tag="VQ543_000442"
     CDS             33679..34638
                     /locus_tag="VQ543_000442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET2611225.1"
                     /translation="MKLSHYLIGLLLLLVFLSISIGTSDFSWGKLFDFDQQTWLLFQE
                     SRLPRTISILLTASSMSMAGLLMQTITQNQFAAPSTVGTTEAAKLGMVLSLFVFPSAS
                     LTQKMLFAFVSSIVFTLFFLAFMTIFTVKERWMLPLIGIIYSGIIGSVTEVIAYRFNL
                     VQSMTAWTQGSFSMIQTHQYEWLFLGLIILITVWKLSQTFTIMNLGKEISESLGISYS
                     LLEKLALFLVALTTSVTMITVGGLPFLGVIVPNLVRKRYGDNLSQTKLMVALVGANLV
                     LACDILSRVLIRPYELSVSLLLGIIGSLGFILLLWRGGRKDAD"
     gene            34628..35584
                     /locus_tag="VQ543_000443"
     CDS             34628..35584
                     /locus_tag="VQ543_000443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001193667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HET2611226.1"
                     /translation="MQTKSKHTKLFWILIILAIGACLLYFWPITHLSAFAWKLRSQKI
                     IVYLLVAIATGISTISFQTLTENRFLTPSILGIESFYVLLQTLLLVFESKFLQLGKSP
                     ILEFLVLLLVQSLFFLTLQGYLKTLMKQDLVFILLICLALRSLFRNISTFLQVLMDPN
                     EYDKLQNSLFASFQHLNTSILAIGSLIILALTIFFFRKAVVLDVLHLQRETAQILGLD
                     VEKEQKELLWGIVLLTSTATALVGPMAFFGFMLANLTYLIVKDYQHKLLFIVAILVGF
                     ISLTLGQALIERVFALEIRISMIIESVGGFLFFILLYRRSRQ"
     gene            35581..36333
                     /locus_tag="VQ543_000444"
     CDS             35581..36333
                     /locus_tag="VQ543_000444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000764290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2611227.1"
                     /translation="MKLENIDKSIQKQDILQGISLEVSPQKLTAFIGPNGAGKSTLLS
                     IMSRLTKKDQGVLSIKGREIESWNSQELAQELTILKQKINYQAKLTVEELVSFGRFPY
                     SRGRLRSEDWEKIRETLNYLELTNLKDRYINSLSGGQLQRVFIAMVLAQDTDFILLDE
                     PLNNLDIKQSVSMMQILRRLVEELGKTIIIVLHDINMASQYADEIVAFKDGQVFSKGS
                     TDQIMQADLLSQLYEIPITLADINDKKICIYS"
     gene            36429..37394
                     /locus_tag="VQ543_000445"
     CDS             36429..37394
                     /locus_tag="VQ543_000445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000858258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siderophore ABC transporter substrate-binding
                     protein"
                     /protein_id="HET2611228.1"
                     /translation="MKTSLKLYFTALVASFLLLLGACSTNSSTSQTETSSSAPTEVTI
                     KSSLDEVKLSKVPEKIVTFDLGAADTIRALGFEKNIVGMPTKTVPTYLKDLVGTVKNV
                     GSMKEPDLEAIAALEPDLIIASPRTQKFVDKFKEIAPTVLFQASKDDYWTSTKANIES
                     LASAFGETGTQKAKEELAKLDKSIQEVATKNESSDKKALAILLNEGKMAAFGAKSRFS
                     FLYQTLKFKPTDTKFEDSRHGQEVSFESVKEINPAILFVINRTLAIGGDNSSNDGVLE
                     NALIAETPAAKNGKIIQLTPDLWYLSGGGLESTKLMIEDIQKALK"
     gene            complement(37619..37861)
                     /gene="yidD"
                     /locus_tag="VQ543_000446"
     CDS             complement(37619..37861)
                     /gene="yidD"
                     /locus_tag="VQ543_000446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertion efficiency factor
                     YidD"
                     /protein_id="HET2611229.1"
                     /translation="MKRILIAPVRFYQRFISPVFPPSCRFELTCSNYMIQAIEKHGFK
                     GVLMGLARILRCHPWSKTGKDPVPDHFSLKRNQEGE"
     gene            complement(37861..38583)
                     /locus_tag="VQ543_000447"
     CDS             complement(37861..38583)
                     /locus_tag="VQ543_000447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HET2611230.1"
                     /translation="MRINKYIAHAGVASRRKAEELIKQGLVTVNGQVVRELATTIKSG
                     DKVEVEGQPIYNEEKVYYLLNKPRGVISSVTDDKGRKTVVDLLPNVKERIYPVGRLDW
                     DTSGVLILTNDGDFTDEMIHPRNEIDKVYVARVKGVANKDNLRPLTRGLEIDGKKTKP
                     AVYEILKVDPVKNRSVVQLTIHEGRNHQVKKMFEAVGLQVDKLSRTRFGHLDLTGLRP
                     GESRRLNKKEISQLHTMAVTKK"
     gene            complement(38570..39139)
                     /locus_tag="VQ543_000448"
     CDS             complement(38570..39139)
                     /locus_tag="VQ543_000448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein B"
                     /protein_id="HET2611231.1"
                     /translation="MSTLAKIEALLFVAGEDGIRVRQLAELLSLPPTGIQQSLGKLAQ
                     KYEKDPDSSLALIETSGAYRLVTKSQFAEILKEYSKAPINQSLSRAALETLSIIAYKQ
                     PITRIEIDAIRGVNSSGALAKLQAFDLIKEDGKKEVLGRPNLYVTTDYFLDYMGINHL
                     EELPVIDELEIQAQESQLFGERIEEDENQ"
     gene            complement(39158..39886)
                     /locus_tag="VQ543_000449"
     CDS             complement(39158..39886)
                     /locus_tag="VQ543_000449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000351912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein A"
                     /protein_id="HET2611232.1"
                     /translation="MDIKLKDFEGPLDLLLHLVSKYQMDIYDVPITEVIEQYLAYVST
                     LQAMRLEVTGEYMVMASQLMLIKSRKLLPKVAEVTDLGDDLEQDLLSQIEEYRKFKLL
                     GEHLEAKHQERAQYYSKAPTELIYEDAELVHDKTTIDLFLAFSNILAKKKEEFAQNHT
                     TILRDEYKIEDMMIIVKESLIGRDQLRLQDLFKEAQNVQEVITLFLATLELIKTQELI
                     LVQEESFGDIYLMEKKEESQVPQS"
     gene            complement(39886..40626)
                     /gene="xerD"
                     /locus_tag="VQ543_000450"
     CDS             complement(39886..40626)
                     /gene="xerD"
                     /locus_tag="VQ543_000450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific tyrosine recombinase XerD"
                     /protein_id="HET2611233.1"
                     /translation="MPMRDRISAFLEEKQGLSVNSKQSYKYDLEQFLDMVGERISETS
                     LKIYQAQLANLKISAQKRKISACNQFLYFLYQKGEVDSFYRLELAKQAEKKTEKPEIL
                     YLDSFWQESDHPEGRLLALLILEMGLLPSEILAIKVADINLDFQVLRISKASQQRIVT
                     IPTALLSELEPLMGQTYLFERGEKPYSRQWAFRQLESFVKEKGFPSLSAQVLREQFIL
                     RQIENKVDLYEIAKKLGLKTVLTLEKYR"
     gene            complement(40617..41078)
                     /locus_tag="VQ543_000451"
     CDS             complement(40617..41078)
                     /locus_tag="VQ543_000451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000560721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HET2611234.1"
                     /translation="MIAKEFETFLLGQEETFLTPAKNLAVLIDTHNADHATLLLSQMT
                     YTRVPVVTDEKQFVGTIGLRDIMAYQMEHDLSQEIMADTDIVHMTKTDVAVVSPDFTI
                     TEVLHKLVDESFLPVVDAEGIFQGIITRKSILKAVNALLHDFSKEYEIRCQ"
     gene            complement(41075..41596)
                     /locus_tag="VQ543_000452"
     CDS             complement(41075..41596)
                     /locus_tag="VQ543_000452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001118598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HET2611235.1"
                     /translation="MAKQTIIVMSDSHGDSLIVEEVRDRYVGKVDAVFHNGDSELRPD
                     SPLWEGIRVVKGNMDFYAGYPERLVTELGSTKIIQTHGHLFDINFNFQKLDYWAQEEE
                     AAICLYGHLHVPSAWLEGKILFLNPGSISQPRGTIRECLYARVEIDDSYFKVDFLTRD
                     HEVYPGLSKEFSR"
     gene            complement(41572..42543)
                     /locus_tag="VQ543_000453"
     CDS             complement(41572..42543)
                     /locus_tag="VQ543_000453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000182414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-triphosphate diphosphatase"
                     /protein_id="HET2611236.1"
                     /translation="MTNKIYEYKDDQDWYVGSYSIFGGVNSLSDYKTDFPLFEFSKIF
                     GDEEYGFPLSVTVLRYGSTYRLFSFVVDMLNQEMGRNLEVIQRHGALLLVENGQLLYV
                     ELPKEGVNVHDFFETSKVRETLLIATRNEGKTKEFRAIFDKLGYDVENLNDYPDLPEV
                     AETGMTFEENARLKAETISQLTGKMVLADDSGLKVDVLGGLPGVWSARFAGVGATDRE
                     NNAKLLHELAMVFELKDRSAQFHTTLVVASPNKESLVVEADWSGYINFEPKGENGFGY
                     DPLFLVGETGKSSAELTLEEKNSQSHRALAVKKLLEVFPSWQSKPSL"
     gene            complement(42540..43334)
                     /gene="racE"
                     /locus_tag="VQ543_000454"
     CDS             complement(42540..43334)
                     /gene="racE"
                     /locus_tag="VQ543_000454"
                     /EC_number="5.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000370386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate racemase"
                     /protein_id="HET2611237.1"
                     /translation="MDNRPIGFLDSGVGGLTVVRELMRQLPHEEIVYIGDSARAPYGP
                     RPAEQIREYTWQLVNFLLTKDVKMIVIACNTATAVVWEEIKAQLDIPVLGVILPGASA
                     AIKSSQGGKIGVIGTPMTVQSDIYRQKIHDLDPDLQVESLACPKFAPLVESGALSTSV
                     TKKVVYETLRPLVGKVDSLILGCTHYPLLRPIIQNVMGPKVQLIDSGAECVRDISVLL
                     NYFEINRGRDAGPLHHRFYTTASSQSFAQIGEEWLEKEIYVEHVEL"
     gene            complement(43541..43789)
                     /locus_tag="VQ543_000455"
     CDS             complement(43541..43789)
                     /locus_tag="VQ543_000455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000364981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YneF family protein"
                     /protein_id="HET2611238.1"
                     /translation="MDLLLAIVLIVLAFLGGALGGMYLVRKQIEKEFADNPRLNAEAV
                     RTLLSANGQKPSEAKVQQVYHQIIRQQKAALANNKKKK"
     gene            complement(43931..45556)
                     /gene="treC"
                     /locus_tag="VQ543_000456"
     CDS             complement(43931..45556)
                     /gene="treC"
                     /locus_tag="VQ543_000456"
                     /EC_number="3.2.1.93"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000171230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha,alpha-phosphotrehalase"
                     /protein_id="HET2611239.1"
                     /translation="MTLDKGKVVYQIYPKSYKDTTGNGIGDFRGIIGKIPYLAKLGVD
                     MVWLNPFYPSPQRDNGYDISDYMAVDPLFGDMADFEEMVCIGKEHKIDFMLDMVLNHC
                     STEHEWFQKALAGDKYYQDFFFIQDQPTDWQSKFGGSAWAPFGDTGKYYLHLFDETQA
                     DLNWRNPNVRKELFKVVNFWRDKGVKGFRFDVINLIGKDEVSVDCPENEGKPAYTDKP
                     IVHNYLRMMNQATFGSDDSFMTVGEMSSTTMENCVLYSSPDRQELSMTFNFHHLKVDY
                     KDGQKWTLAPFDFEELKSLYHSWGKEMSDKDGWSALFWNNHDQPRALNRFVDIQNFRK
                     EGATMLAASIHLSRGTPYIYMGEEIGMIDPDYDSMADYVDVESLNAYQMLLEEGKSQQ
                     EAFQIIQAKSRDNSRIPMQWDASENAGFSTGTPWLKAGKSYKDINVENEIQGPIFTFY
                     QDLIRLRKEMPIISEGSYKPAFEDSKQVYAFERQFEDQKLLVLNNFYAKEVEIDLPAV
                     YQNGQILISNYEDAEVSEKILLKPYQTLAIYVN"
     gene            complement(45734..47701)
                     /gene="treP"
                     /locus_tag="VQ543_000457"
     CDS             complement(45734..47701)
                     /gene="treP"
                     /locus_tag="VQ543_000457"
                     /EC_number="2.7.1.201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system trehalose-specific EIIBC component"
                     /protein_id="HET2611240.1"
                     /translation="MGKFEQEAKDLLQAIGGKENVTAVTHCATRMRFVLGNDKKANVK
                     AIESIPAVKGTFTNAGQFQVIIGNDVPIFYNDFTAVSGIEGVSKEAAKSAAKSNQNVV
                     QRVMTTLAEIFTPIIPALIVGGLILGFRNVLEGVHWSMLDGKTITESSQFWAGVNHFL
                     WLPGEAIFQFLPVGITWSVSRKMGTSQILGIVLGICLVSPQLLNAYAVASTPAADIAA
                     NWVWNFGYFTVNRIGYQAQVIPALLAGLSLSYLEIFWRKHIPEVISMIFVPFLSLIPA
                     LILAHTVLGPIGWTIGQGLSSVVLAGLTGPVKWLFGAIFGALYAPFVITGLHHMTNAI
                     DTQLIADAGGTALWPMIALSNIAQGSAVFAYYFMHRHDEREAQVSLPATISAYLGVTE
                     PALFGVNVKYIYPFVAGMTGSALAGMLSVTFNVTAASIGIGGLPGILSIQPQYMLPFA
                     GTMLVAIVVPMLLTFFFRKAGLFTKTEGDTNLQAEFVAQEEAEFVNHEPVELTSVEII
                     SPLTGQVKELSQATDPIFASGVMGQGLVIEPSQGELTSPVNGTVTVLFPTKHAIGIVS
                     DEGVELLIHIGMDTVGLDGKGFESLVVQGDHVTVGQQLIRFDMDVIKAAGLVTETPVI
                     ITNQDAYTATIPGTYPTTIQAGASLMVATRI"
     gene            47886..48596
                     /gene="treR"
                     /locus_tag="VQ543_000458"
     CDS             47886..48596
                     /gene="treR"
                     /locus_tag="VQ543_000458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trehalose operon repressor"
                     /protein_id="HET2611241.1"
                     /translation="MKKYQQLFKQIQETIQNETYAVGDFLPSEHDLMEQYQVSRDTVR
                     KALSLLQEEGLIKKIRGQGSQVVKEETVNFPVSNLTSYQELVKELGLRSKTNVVSLDK
                     IIIDKKSSLITGFPEFRMVWKVVRQRVVDDLVSVLDTDYLDMELIPNLTRQIAEQSIY
                     SYIENGLKLLIDYAQKEITIDHSSDRDKILMDIGKDPYVVSIKSKVYLQDGRQFQFTE
                     SRHKLEKFRFVDFAKRKK"
     gene            complement(48629..49432)
                     /locus_tag="VQ543_000459"
     CDS             complement(48629..49432)
                     /locus_tag="VQ543_000459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000157668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HET2611242.1"
                     /translation="MASLLTLENIHKTFEAGTVNENHVLKGLDLEVEEGDFISVIGGN
                     GAGKSTLMNILAGNLSVDEGDLLLAGKSIKHLSVRKRAKDIARVFQDPKMGTASRLTI
                     EENMAIALRRGQKRGLGWGVKEKDRIQFQEALKELNIGLENRLKVDTQYLSGGQRQAL
                     TLVMAALVKLKLLLLDEHTAALDPKTSQMVMDLTQKIVEYHQWTTLMITHDMNHAIEY
                     GNRLIMLYQGKIVVDVKGEEKKHLTVEDLMHLFQKNSGQSLVSDELVLG"
     gene            complement(49445..49873)
                     /locus_tag="VQ543_000460"
     CDS             complement(49445..49873)
                     /locus_tag="VQ543_000460"
                     /inference="COORDINATES: protein motif:HMM:NF014684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2611243.1"
                     /translation="MKTEIGLVLRSTGDNIPMSEANGVNVNTMKIVGYMISTGLIALC
                     GSLFAQNDGFSDVTSGTGTIVVGLSSEVLIHDLTIGGRLLSIGIGAIVYRLIILNIYE
                     IPNLDQNLVRLFNAILLALVLFAPALQKRLKIRGLKLRNE"
     gene            complement(49882..50322)
                     /locus_tag="VQ543_000461"
     CDS             complement(49882..50322)
                     /locus_tag="VQ543_000461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001853886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET2611244.1"
                     /translation="MNFVLSSLSEGLLWSIMAIGVYLTFRILDIADMTAEGAFPMGAA
                     IVVSQIQAGANPWLATLLALLAGMVAGLISGMLHTKMKIPALLTGIVTLTGLYSINIK
                     IMGSVPNLSLGDSATVFKQLASLGLTNEGAVFSLSLVCLLLVWF"
     gene            complement(50367..51272)
                     /locus_tag="VQ543_000462"
                     /pseudo
     CDS             complement(50367..51272)
                     /locus_tag="VQ543_000462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000512061.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
BASE COUNT        15175 a        11736 c         9477 g        15288 t
ORIGIN      
        1 attaaaaggt taagtaattt ttccaaaata cagcactcat atagacagta tcatcaatta
       61 tagccattgg gattttttga ttgccaattc catgtatctc tacacatgtc ttcaatcgat
      121 tttgttgtcc tccaatttaa ttccttatat gctttgtctg catttgcata ataagttgca
      181 acgtctcctg aacgtcttgg aactatttta taaggaatag ggatcttatt aacactttca
      241 aatgtattta caagttgtaa tacactagtg ccttctcccg agcctaggtt atagatataa
      301 acatctgttt tttcagatac tttttctaaa gcttttatat gtcctattgc taaatctact
      361 acttgaatct tttatctcat ttttcccttt ttcaaataag ttatctactc tatgatcagt
      421 tatttccatt tcgtttacta acatgacgca gtcacctagc atcatatact ccaacttttt
      481 ttctgaaagt ttagcaaata ttggtaagcg ataatatagt atattgaaac tagaatagta
      541 cacctctact tctaaaacat tgttagaaat cgatttgact gtcctgattg atttgtccta
      601 ttattatttc attttactat actctgttaa ttcatatgag tttaaaccga tttcatcttt
      661 aacctcgagt aaagcagttt caaatatttg tttaagagtt tttgattctt tacaattaac
      721 cgacaaactt tctgataaaa tatgtacaac ttctgagact gaataaccta tctcctcttt
      781 agaattatat aaatctgtag ctccaccaat aatccaaaaa tactgatttt gtgaacctac
      841 aatatcctca ttttctacgg aacttccttg tatcgaacaa attttattta tctttaccat
      901 aatacttcaa cccttttagt gtcaaaagta aaccaattcc tgtcactgtt aagaatagtt
      961 ccataatctt gttcgaacca gtctttggta atttttgttt tacatctact atttctttag
     1021 atttattaat atgattttca gtttctctgc catctccaac tattttatag tttacttctt
     1081 ctgtcttatt atcttgttta ttgtcgatct tgtcattcat ttgtctatta tctttacttg
     1141 agttaaactc tccgttcttc tggttactat caattacatt atttgaatta gattgttttt
     1201 cctctttgtt tttttctttt tcgtttttat cacttaaatt atttgttaca attttgtaaa
     1261 gcccattctc cgttacaata ttgaaattac catcgctatc acgtataaca gattctttcc
     1321 catttgcatt agatttgatg aatgatatat acttaccgga taaattataa aattggttat
     1381 ttaaaacggt tattttaccc tttgaatcct caataacaat tccttcttta ccaccgaata
     1441 tactattctc tgagactact aaattatcac taactcgtaa taattcaata tttggttgtt
     1501 ctgtttcctt agaattatta ttaattacat tttttgttac agtaatatct gatacttttc
     1561 ctaaatattc tgcactatct tttgcaactc gtatcgcttt tgttttagga tcggcaatat
     1621 taaatatatt ttcggcgata accacctgtt tatttaaatc taataggtct ttagtgtttt
     1681 tatagctata agcatttact aaagctgctc cgctttctcg ataatgtaca ctctctcctt
     1741 taactttctt atcaaagcga tttcctttga ttaatacatc agtgaatcct gtaaaacgta
     1801 cacctgcata catcatgtta tcaaaatgat tatttaaaat tttaatatta gaggggttct
     1861 gtgtcgacaa tgtttgatag tgtgtgccaa ttgctgttac taattcccca gatttatcac
     1921 ttttgccaaa ataggaattt tgaatagtca cattttcaga ttttttccca tcatcattca
     1981 aggcataagg aaaacctttt ctagttaatg gttcaatctg aatgctctcc ttacttatga
     2041 tttgcccatc cttcatcgtt ttgggtaagg cttgcccaag aaaacgagaa ttatcaacta
     2101 atacattttt cgaacctgca atttgaatag catgcccttg ataactatcc ttgaatgtta
     2161 cattttttat agttacgtta tttgaattcc caatagcaaa tgcacctgaa gaatttataa
     2221 gtggtagatt ttttgcttta gttccttctt cattcaaagc accgttcata tcaatcgtac
     2281 caccagaata actaatatct tctgttgggc cccattctac ttgcgcacca tcatccgtaa
     2341 ataaacctgt cataaaaaca atggaagggt gattcttaat atttatacca tttagaattg
     2401 tagctttctc attcaattct aagtgtgtat gactttttaa aaaaacaatt tcttttacta
     2461 aataagttcc ttcaggaaaa tatacatttc ctccacctag cccttgagct gcagcatcta
     2521 ttgcatcttg aattgcttgt cgatcatcat gaatcccatc acctaccgca ccataatctt
     2581 ttacacttaa agcagtatct tcaaattctt ttttgataat tctgtcactt ataacatctt
     2641 ccttataact cttattttca ttagtagata ttactgtaga ttcaactgtt ctgttgtcta
     2701 attgtgaatt ggaacgaata gtaccattag agctgatact attaacactt aacgaattat
     2761 ctaaaccatt agtggttgaa ttagaggcaa tcatttcagc agaacgattt tgattaacag
     2821 ttggtgaatt atctaaatca ttagtgattg cattagaaga ctcttttgta gccatcggtg
     2881 aagaactagt aacaacttca tccgataaaa taccttggct tcccaaaatt gaaattgcca
     2941 atagtaccga gcaagtcccc acctttaatt tacgaatact gaatacctca ttaggaacaa
     3001 aatatttcat cagaacctcc aattttttta ctatttttaa caattgatta ttacttttct
     3061 taaaatagat agaatgacac cgctgtcatt atctttatca tatattttcc aaattgaatt
     3121 gtcaaggaat aacacaagaa aatattaaaa tttatactct tcggaaatct cttcaaacta
     3181 ggtcagtgcc gccttgccct aagtctaggt tactgacttg gtcagttcta tagtagactg
     3241 aaactataat agtacacctc tacttctaaa acattgttag aaatcgattt gactgtcccg
     3301 atcgatttgt cctattctta tttcatttta ttatatctac aacctcaaag cagggttttg
     3361 agctatctat ggccaacttc ctagtttgct ctttagcctt ccattcaaaa gtgatgctat
     3421 ctttcttagc ttgaatataa aatatcccat ttactatatt taaatttgtt gatatgttgt
     3481 aaattataaa tgaaagaaca aatatcttgt catacaagca ttcgccaggg atatttacat
     3541 gaatatcgct catatggcgg attgaaacta aaacactaca atatatttct taaatagacc
     3601 ttctataaaa gctagattta acctcgataa aaatagatgc agtgcttcta aaatactgga
     3661 atagggcata taggtaatcg tagacaagtg ttttatagat tgtctcgcgg gagatctaat
     3721 gatgtatagc aagcatcact aaacatatag aatatttgtg ttattataat gtcaatatgc
     3781 tataaattct atcatgcaaa agaatgacta gaacatgaaa gacaggcaca aaactttgaa
     3841 caatattctg aaaacaaaaa aagacgcgag tttccacaat ctcactcatg gaaactcacg
     3901 tctttcaaaa aatagggtga attaaaaact agaacaagac actagatttt ctaaatgatg
     3961 tctagtaagg attctaaatg ctacaccaaa ttgctcacat cttatttcaa accacgggac
     4021 tcccacaaga aaggaaaatc ctataaaaat tctctctctg aggagagaga ggcctcaact
     4081 acaggtgtaa actattatca attgaaaaca acagttttta cactcaatta gactttttag
     4141 ggacaggatc actttcgctt gactgtagtt tgtcattttt ttgataaagt tagcactttt
     4201 tcagaaactg ttttgaaagt ctcaatgata tagtctactt cttcatcgct taatttagta
     4261 tgaagaggga gggtaatttc attctcaaag aaggcatagg ccttaggata gttcgtcata
     4321 tcaaatccaa gattcttata ggctgtcaag agaggaagcg gtttgtagtg aacattactt
     4381 gcaattcctg ctttagccaa ttcttggatg atgaggttgc gttcttctag gcttgctcct
     4441 tctacacggg tgatgtagag gtggcgtgaa gattcgacag tttcagtctt gtgtgccaaa
     4501 ggatggatgc gagaacctgc aaaaccacta tcatagcggt ccacaatgtc cttacggcgt
     4561 tgcaacaaac ttggatagcg gtccaattgt accaaaccaa gtgaagccat gatatcggtc
     4621 atgttgcact tataggctgg tgtaacgata tcgtattccc atgaccccag ttgcatcttg
     4681 gcaagagcat ccttagtttg cccgtgaagg gaaaggattt ggaattcctt gtacatctct
     4741 tcgtcatcaa tcactggatt ggctttccaa gtcgcacttc caccttctgc cgttgtaaag
     4801 ttcttaacgg catggaatga gaaggaagta aagtcagcga tagaaccaga aggttgtcct
     4861 ttataagtag atcccaaagc gtgggcacta tcagagacaa tgacaatacg gttaaaggcc
     4921 ttttgccact tgcttgaagc ggtaaagaag tcacgttttt tctccacgac ttggaacaaa
     4981 cggtcataat cgcaaacaat ccctgcgagc tctactggga taatcacctt agttttctca
     5041 gtgatagctt gctcaagcag gtcatagtcc atctcaaacg tatctgcttg gatatccacc
     5101 atgacagggg ttgctcccac gtgcgtaatg acactacatg aagccgtata ggttatggct
     5161 ggaacgatga cttcatcacc aggtcccact tcaaaaacgc gtaaaatcaa ctccagagcg
     5221 gctgtcgcag agttgagaca aacagtctta ggtgtctgtg tgtaaagaga caagcggcgc
     5281 tccagttctt ttgttttagg acctgttgtg atccaaccag aacgcagggt atccgctact
     5341 tcagcaattt ctgcttctgt gatatcaggc ggtgaaaatg gaatattgta atttggcatt
     5401 gatttgctcc ttttatctgt actcattctc ttatgactac tttattttag taccttaaac
     5461 acggtttgaa acatgatttt gatgtcccca aagaaactaa actctcggag ataggcgagg
     5521 ttatagcgca tcttttcagg aagaacatgc tccacatagg cctgatcaac tgacagacct
     5581 ttctctgtca tttgactgat gatggtgtcc tcatccttgt agttgatgct ggctggagag
     5641 gtaattcctg cttgcaagag caaggttgcc atcatttcag tgctatactg ctctgtataa
     5701 cgtggcactt caggtcgtgt accgacaaag gacatctcac ctttaaggac attgaccaac
     5761 tgaggcagtt cgtccaaacg gacacgtcgg atgaaatttc caaccttggt aatacggcta
     5821 tcgttagcag aagtcaccag atttcctttt ttatccgcat ccgtcaccat ggtacggaac
     5881 ttccaaatct tgaaccgacg gttgtactgg gtcacacgct cttgcttgta aatcactggc
     5941 cccttgctat ccaacttgat ccaaatgctc aagatgagaa agatgggaga ggtcagaacc
     6001 agtaagacca aggccaaaac ccagtccaag caacgcttga aaatcagcga acccttcctt
     6061 ttagagacaa gctggtagta agactcaacc tcgcttgatt tcatttccac aggcaagtct
     6121 tcccatttca gcatgctgtt ctcctttgtt tttattatac tatttgtcaa cactttttgt
     6181 caacactttt cattatacca caaaatggaa aaggcggtga aaaaaatctg taatttgaag
     6241 gatttccttc tagtactcaa tgaaaatcaa agtacagctt tgagattgca gataaagctg
     6301 acatggttta aagagatttt caaagagtat aggccatggc ccctgcctgc aaactataca
     6361 tcttgtgata ggttcctccc agagccaaga gttcctcatg ggttccactc tcgataatgc
     6421 gtcccttatc caagacatag atgcagttgg cgtcttgaat agtagaaagg cggtgagcta
     6481 tagcaatagt tgttcggccc tgtctcatct tcgccagaga agcttgaacc aagctttctg
     6541 tttcagagtc aatattggct gtcgcttcat ccaaaatcag gattttaggc tggctggcga
     6601 ctgttctagc aaaggcaaga agctggcgtt gcccagtaga gaagctcgaa ccacgctcgg
     6661 aaacagggga gtcgtacccc tgaggaagtt cttgaataaa ggaatctgca tccacaaagg
     6721 ctgccgcagc ctgaacctgc tcatcactga tttcttggta catggcgata ttggacttaa
     6781 tagttccatg atagaggaag ggttcctgca agaccaaacc gatgtttttt ctcagctctt
     6841 cttgactgaa atccctgata tccacatcat ccaagagaac tctccctgac tggaattcat
     6901 aaaagcgcat gaggacattg ataatagacg atttccctga acctgtatga cctacaaagg
     6961 caatggtttc acccttatta acagagaaag aaatgtcatc cagaatcgga tgtttaccgt
     7021 catatgagaa acacacatgt tcaaagcgga tattgccttc ttggactttg gcttgcccat
     7081 tttcttgaag aggttcatag gtcctctcgt ctaccagggc aaagacacga cctgcagaaa
     7141 ccatagacgt ttgcagtgtt gaaaagtttt gcgtcacctc aatcaaaggg tcaaagaggc
     7201 ggttgatgta ctggataaaa gcatacatgg tcccggccgt tatcccgata gaaagaccac
     7261 gatagccaaa ataggccatc aagacagcat aacctagaag tttcaacaaa ctcatggcag
     7321 gtctcaaaaa gagggcatcc aaggctacag aacggttggc atagaccaag tgctcttggt
     7381 tgatttcatc aaattctgcc tgcaggcgct tctcttgatt aaaggcctgg attattctga
     7441 ttccctcgat gttttcagcc agcttgctat tgatatctga caagagactt ctggttttct
     7501 caatgatttt cactgatttt ttccgataga gattgaccaa aaggaaaatc aaggggagaa
     7561 agagcaagac taatgctgtc aaacgaaaat ccaataccaa catggtataa agggttgtca
     7621 gaaagatgaa aactgctgag ataaagctag ataaaatccc agaaaacata tcactaatcg
     7681 tctcggtatc gttggtcaaa cgagaaacga tagaacctgc tggcgtcttg tcaaagtaag
     7741 acatgcccag tttctccata ttggcaaagg catcccgacg aatatcccta acaatactgt
     7801 aagacacgcg cgcaaagaga agattgccga catactgaac tacagtttgt aggatgtaga
     7861 gaccatagta gaccagcaaa acggtaacgg ctagttggtt aagattgctg agatactggt
     7921 cgataaagtg ggaagccacg aggggtatga cacttttaat gaccgtcgtc gctaggagaa
     7981 aactgagtgc caaaaaggtc aggagtctat aaggcttgag ataagacatc aagcgcttca
     8041 atacagccca ttgttcttgt ttattctgca tcttcttctc ctttcatttc taactgctga
     8101 gactggtagg tttgggcata ccagccatcc atcgctagca agtcttcgtg cctgcctcgt
     8161 tcgataattt gaccattttg tagaactaaa ataaaatctg catggacaac agcactgagg
     8221 cgatgggcag ttataatggt tgtcttgtcc tttcgcgtct ccttgagatt gtcgataatc
     8281 gcatactctg tcttggcatc tacggcggat aaggaatcat ccaaaatcaa gatatcaggg
     8341 tttaaaatca tagcccgact catagccaac cgttgctttt gaccaccaga aagactgact
     8401 cctttttcac caatcagcgt atcaaatcct tgaggcatgt ctacaatatc ttggtaaact
     8461 cgggctagct tagtagcttc ctcaacctct gaaaggggca agttaggatt gccaaagcgg
     8521 atattgtcta ggattgaagt cgcaaagaga aactggtcct gaggaacata gcccatgaga
     8581 ctgcgaagtt ctgtcaaacg atagtcccga atatcgtgac cgtttagata aatggcaccc
     8641 ttatccacat cgtattcacg caagaggagc ttgattaagg acgttttccc agagcctgtc
     8701 tgcccaacca agcccagtgt ttgccctttt gccaaactaa agtgaatatc cgtcagtgtt
     8761 tcctcatttt caaaagcaaa gctgtcaatg gcatactcca aacgcccatt ttcaatacca
     8821 tccagaggaa actcagggtc ttgtacagga gattcctgag acaaaagatt ttcaatccgc
     8881 tggtaagaaa ccttccctcg ctgagtagta ttaaagagga agccgatggc cataagaggc
     8941 cagaccagca tatccaaata gctgataaag gtgactagat taccaactgt aatctgccct
     9001 tcctgaacca tcaaggagcc aaccaaaagc gttaaaacat aggacgaacc aacaaacaag
     9061 agaaccatag ggtcaaagag actatcatat ttcatggttt gcaggttctt ttggaaggtt
     9121 aattcattga ctgcctgaaa agacttcaac tcgtctgcct gataaccgaa agacttggtc
     9181 actttgatac ctgatacgga ctcctgtacc ttgttattga gttcagaaaa agcagcttgg
     9241 gattcgccaa aggccttatg agtctttctc cctaggcgac tagtcgcata ggccatgaaa
     9301 ggtaggggga gaatggcaac aagagtcatc tgccatgaga tgctaaagag catggtcaac
     9361 aaagtcacca gagccgtgat agaggcatcc accgcagaca tgacaccgcc acctgctaaa
     9421 cgagtcaagg cattgatatc attggttgcg tgtgccatca gatcacccgt ccgataggtt
     9481 tgataaaagg ctggcgacat ttttgtgaaa tgcttaaaca agcgagaccg catgatctgt
     9541 cccaagcaat aagaggtccc aaggatatac atacgccaca catagcgcaa atagtacata
     9601 ccaaaggctg caagtagcaa gtaaaatagg ctaagaagga ggtcctgctg ggttaattgc
     9661 cccgatgtga tggcatcaat gactcgcccc ataaccatag gaggaatgag attgagaacg
     9721 gaaaccaaga ccagggccac aatcccgact agataacggt gtttttctaa cttgaaaaac
     9781 caccagagtt tttgaataat ggacataaaa tccctttctg attgcaaatg gaaacctgag
     9841 gccaatactc aatgaaaatc aaagagcaaa ctaggaaact agccgcaggc tgctcaaagc
     9901 actgctttga ggttgtagat agaactgacg aagtcagtaa cctacatacg gcaaggcgac
     9961 gttgacgcgg tttgaagaga ttttcgaaga gtacaagacc ccaggttttt cttattcata
    10021 agttacgact gtaacagcac ccttgtcata ttcagcaata aagatattgg ctacattgtc
    10081 atgcccttgt ttgctgaggt tatcaagcaa ccactcttcg ctacgaccaa tcgattccaa
    10141 gacgtctact tgaatcacac cgtcagtcac aactggatac ttaggatttt catctcccat
    10201 ttgcacaacg atgagttgcc cattttgctc ttgcacagct cgtttgactt gcttcatctg
    10261 gaaaatccct tggctacgaa gtttgagggc tacatccgat gcagacaaac caactgaacg
    10321 acaggcttat gggtcaatat tcccattttt gataaggaga gttggcttac catcaatcaa
    10381 acgtttcaca aagtgaacat tgttgttgag ctatttgaga gtcaagatca gtttgattaa
    10441 aatttcgata taattaagtg tcatttgttc acatccacca gttcaattgc gtctgtctta
    10501 tacaattcga ctttctctaa caggtacttg tctggctcac ttccgtttag ggcacgataa
    10561 tagcgatctc ccaccttgat aagtgcgcca tctgtgtttg tggaagtatt aacatggact
    10621 tctgacttgt ctactcccaa atctttggaa acaacctcga tgaaatgaag tgaagtttga
    10681 aatttattgt tagaaacttg attgttttga taagtcgtga tgctgaccaa aagcatagct
    10741 aaataaggcc agagctgaaa tcatgaccaa ctcacgaaat ttggttcctt ttttatcatg
    10801 gtatgccttg aaagcaaaaa aaactgtcac agctaataga acaatcccaa agccaaccat
    10861 gataccattt tgctgaccga tttggctgag tacatagtca taagagtaga atttcatgta
    10921 ttttcactcc ctttcataaa atcattctta attataaacg aaagagagta atttttcaaa
    10981 ccatacgttg gggaaataga tctttttttg gtataataaa atctataatc tgaatgaaaa
    11041 aggtaacttt atgaaactta tctcatggaa tattgattcc ctaaacgctg ccctaactag
    11101 tgactcagct cgtgccaaat tgtcccaaga agtcctacaa accttggtcg ctgaaaatgc
    11161 tgatatcatt gctatccaag aaaccaagct ttctgccaaa ggacctacaa agaaacacgt
    11221 ggaaatttta gaagaactct tcccaggcta cgaaaacacg tggcgctctt cccaagagcc
    11281 tgcccgtaaa ggctatgctg gaaccatgtt cctttataag aaagaactta cacccactat
    11341 cagcttccca gaaatcggtg ccccttctac catggacttg gaaggccgta tcatcactct
    11401 agaatttgat gcatttttcg taacccaagt ttacactcca aacgctggtg acggtctcaa
    11461 acgcttggaa gaacgccaag tctgggatgt caaatatgcg gagtatttgg ctgaactaga
    11521 caaagaaaaa ccagtccttg cgaccggtga ctacaacgta gcccacaatg aaatcgacct
    11581 tgcaaatcct gctagcaacc gccgttcacc tggatttact gacgaggaac gtgctggatt
    11641 taccaaccta ttggcaactg gatttactga taccttccgc catgttcatg gcgatgttcc
    11701 tgaacgctac acttggtggg cacaacgcag caaaacttct aaaatcaaca atacaggctg
    11761 gagaatcgac tactggctca caagtaaccg tatcgctgac aaggtcacta aatctgatat
    11821 gattgactca ggtgctcgcc aagaccatac accgattgtc ttggaaattg acttgtaagg
    11881 attttctata tggactacaa tgcggtcatt cccgagtttc ttgtatcgaa tatcgaacag
    11941 tcccggtcct tctactgtgg tttactgggt tttaggattg aataccaacg ttcagaagaa
    12001 aactttctct ttctcttgaa gagtgtcaac taatgttaga ggagggaaca aaggatcaac
    12061 tagctgaact gacctacccc tttggtcgtg gagtcaatct ctcctttggc ataaaggatg
    12121 ttccaaaact ctatcaaaaa gtgatggagg caaactatcc tatttatcgt cccttgacca
    12181 aaagaaagtt tcgtgtcagt gatccctata tctatcctca taaatttgca gttttggatc
    12241 cagatggcta ttttttaaga tttagcgagt agaataataa aaattgggaa aagtctttaa
    12301 aagttagaaa aaggcatatt gtcaggtgtc taaaaacttg atagtatgcc ttttatgatg
    12361 gaaaaatctt ctaatactct tcgaaaatct cttcaagcca cgtcaacgtc gccttaccgt
    12421 aggtatataa tactgactct gtcaattcta tccacaacct caaaacagtg ttttgaggtt
    12481 gtggatagct tcctagtttg ctctttgatt ttcatttagt ataaatgtta gcttacaatg
    12541 gagtttttgt tcaccctctc ttctgtttgt tcgtttttta aaccaaaaca ctaacaaaat
    12601 agttgatttc taaagttatt tagtgtaaaa taaaaacatt ggctcaagcc tatttaaaat
    12661 tgaatatcgt tttacttgtt tatgtcgtga attggcacga cgtttctaca aggtgccgga
    12721 acacctaaca ataagtaagt cagcagtgag atatggccgt ttttgccatg cctatttggg
    12781 ggacttactt agagattaag taggtctttt ttgaatattt ttaatatttc ccttaattag
    12841 tgcggacggg aggtgaaatt atcctgtgaa taatttcagg aatccaggga atttcatccc
    12901 taatttttga gcccctagct ctttcatttc taggcttagg ctaaaatagt tccccgaact
    12961 attttactct caaaaatccc gtcatagaca ataacaagat tattgtctat gataccacta
    13021 caacgggaaa tatttgataa gactcgcttc gctcgtaata gttttatcaa atatatagca
    13081 ttagcaaaag ggatcactat agaaacattt aaacaacaag taaattaact tttagacttt
    13141 aggaggtctt atgaaattat tagaagagcg catcctcaag gatgggcata tcttgggtga
    13201 taacatcctc aaggtagatt cctttttaac ccaccaagtt gactttagct tgatgcgaga
    13261 gattggtaag gtttttgcgg aaaaatttgc tgctgccggc attaccaagg tcgtaaccat
    13321 tgaagcgtcg ggtattgccc cagccgtttt tacagctgaa gccttaaacg ttcccatgat
    13381 tttcgccaaa aaagctaaga acatcaccat gaacgaaggc atcttaactg ctcaagtcta
    13441 ctcctttacc aagcaggtga ccagcaccgt ttctatcgct ggaaaattcc tctcaccaga
    13501 ggacaaggtt ttgattatcg acgatttcct tgctaatggc caagctgcta aaggcttgat
    13561 tcaaatcatc gaacaggccg gtgccacagt ccaagctatc ggtatcgtga ttgagaaatc
    13621 cttccaagat ggccgtgatt tgcttgaaaa agcaggctac cctgtcctat cacttgctcg
    13681 tttggatcgt tttgaaaatg gtcaggtcgt atttaaggag gcagatctct aatgcaaact
    13741 caagaaaaac actcgcaagc agccgttctt ggcttgcagc acttactagc catgtactca
    13801 ggatctatcc tggttcccat catgattgcg acagcccttg gctattcagc tgagcagttg
    13861 acctacctga tttctacaga tatcttcatg tgtggggtgg caaccttcct ccaactccaa
    13921 ctcaacaaat actttgggat tggactccca gtcgttcttg gagttgcatt ccagtcggtc
    13981 gctcccttga ttatgattgg gcaaagccat ggtagtggcg ctatgtttgg tgcccttatc
    14041 gcatctggga tttacgtggt tcttgtttca ggcatcttct caaaagtggc caatctcttc
    14101 ccctctatcg taacaggatc tgttattacc acgattggtt taaccttgat ccctgtcgct
    14161 attggaaata tgggaaataa cgttccagag ccaactggtc aaagtctctt gctttcagct
    14221 attactgttc tgattatcct cttgatcaac atctttacca aaggatttat caagtctatc
    14281 tctattttga ttggtctggt tgttggaact gccattgctg ctactatggg cttggtggac
    14341 ttctctcctg ttgcggtagc tccacttgtc catgtcccaa ctccactcta ctttgggatg
    14401 ccaacctttg aaatctcatc tattgtcatg atgtgtatca tcgcaacggt gtctatggtt
    14461 gagtcaactg gtgtttatct agccttgtct gatatcacaa aagatccaat cgacagcacg
    14521 cgccttcgca acggttaccg cgcagaaggt ttggccgtac ttctcggagg aatctttaac
    14581 accttccctt acaccggatt ttcacaaaac gttggtttgg ttaaattgtc aggcatcaaa
    14641 aaacgcctgc caatctacta cgcagctggt ttcctggttc tccttggact gcttcctaag
    14701 tttggtgccc ttgcccaaat cattccaagc tccgtcctcg gcggtgccat gctggtgatg
    14761 tttggttttg tatctattca agggatgcaa atcctagccc gagttgactt tgctaacaat
    14821 gaacacaact tccttatcgc agctgtttca atcgctgcag gtgtcggtct caacaacagt
    14881 aatctctttg tcagcatgcc gacagccttc caaatgttct tctcaaacgg aatcgtcgta
    14941 gccagcctac tcgccattgt cctcaatgcc gtattaaatc ataaaaagaa ataagaaaaa
    15001 gaggtgcgag cctctttttt gtttatcaca aattgattat aaatacaatc aatcccaatt
    15061 cccatctaat tgaattggac ctatttcaaa ttctttaaaa tattatgttc caaatcgtta
    15121 atattatata agaatggtaa aatatcaaat gtttctcgta aattattctt agccttatac
    15181 caaccttgtc catcagtaat ccacataaac tcaacattag gaatagcttt aatttcttca
    15241 gcaatcattt tgtaagatct agccgtctca tttaattttg aaccacttcc tgaataaaaa
    15301 ttaacctcaa tcagataaag cacttgttca ttttttatga caaaatcaaa acgtttcaca
    15361 gtattcccat cattcgtaat agcagataaa tcgacagaaa aaatttcctc tatttcattt
    15421 tgttcaatct ctttaaataa attctctcct aaaatatacc cttcagcttc aagataactt
    15481 tgaacaatat tttccatcgc atctccagtc cgatttttgc gcccattagt atccatacca
    15541 acctcaacac ctgtaacgta gtcaactaaa tttgatacta aatgattttg caataaatca
    15601 aatatacctg atttttccaa aaacatagta tattcttcaa tactatagtt tcgtttacta
    15661 aaatcaaaat agaaatcttt tatcggatcc ttaacaataa tcgtatctct caaacgttta
    15721 gcaataagta gaggcacaac tttcaaaatt tctggataat tttgatataa gtctaaaaaa
    15781 tcctcttgta tatttttact accaataaga ctattcataa tatttagagc aacttttata
    15841 ctagatacat ttttataaac cttgggaaaa tctgtataat aagtccagtc agctactgtg
    15901 tcggtcatcg ttgacaacca ctcatcaaaa tttctagttt gtttcatttt ctgcctccaa
    15961 cctcttcctt gcaattttta aatattcttt ttcagcatcg atacctataa atcttctacc
    16021 taaccgcttc gcaacaacac ccgtagtgcc actaccaaca aatgggtcta gaatatagtc
    16081 accctcttta gtagaggcta aaataatgcg ttctaacaaa tactctggtt tttgagttgg
    16141 atgtttccca gcccattttt caactttctt tgttaaagaa cccgtccaga catctttcat
    16201 ttgttttcca tcattcaatt ctttcattaa atcataattg tagtaatgac gagctttttt
    16261 atcatttttt ctggcccata aaatggtttc agtagaatgg gtaaaataac gacaagataa
    16321 attgggggca gggtttgttt tctgccaagt aatattattc agaattttaa aaccttcttg
    16381 ttctaatgcc attccaactg agtatatgtt gtgcaaacta cctgaaatcc ataccgtccc
    16441 attaggcttc agaacttctt ttgctaggcg aatccattta cgattaaact catgtttttc
    16501 ttcgaatgaa gaaattttat cccaatctcc tttatcaaca gaaacaactt gtcccccaga
    16561 attagatatt ccaccattac ttaaaaaata aggtggatca gcaaaaatca tatccatact
    16621 ttctggtttc atttttgata agaacttgaa cgtatctgaa tgaacaagaa tcatcttatt
    16681 tttattgtag tatggttttg tcataagaac acctccatac ttatattcgt tatttttcat
    16741 aatttgtgac tataatttca gaaatttttc ctcgacttga agattttgct ccattagttc
    16801 gggtagcttc aacataatgt atattaaaat ccttatacaa ctcctctact aaagcactag
    16861 aagaatttga taacataaca taagctcctg tatcactcaa tctcttaaag gcatctctta
    16921 atcttacttg atctgcaaaa gagaatccct catgagtata agacgtaaat gcactcgtct
    16981 cagacaatgg aatatatgga gggtcaaaat acacaaaatc tcctgttcga acatctacaa
    17041 ttgccttttc aaaatctccc actttaattt ctagttgatt gttatttaga taaactgaaa
    17101 tagcagatat caattcctca tcaacaattt taggattctt ataacgtcca tatggaacat
    17161 taaattggtt cttagaattc acacgatata gaccattaaa gttcactctc aacatatata
    17221 gaatacgtgc agctctttgt acttcggaca tcatatctat tctttcatca cgatctgcag
    17281 aacgtaaatc taaataatat tcttttgaat tatattcctg atgaactttc aaaatttcaa
    17341 tcaattcttg aggattgtcc ttaatttgtt gatagcaatt tattagttca gcgttaaaat
    17401 cattaataac tgcatcttta ggagccaaat caaaaaataa agctccacct ccaacaaaag
    17461 gttcgaaata cctgttatag gttttaggca ttaattctct aataacaggc aataattgtc
    17521 ttttaccacc tgtccatttc gtgaacggtt gtaaagtaac tttctttatt tcttttatct
    17581 tcatgctttt aattatacca tagaaattaa aacacaactc ttgtattttc taccacatta
    17641 ctaaattttc tattttagaa ttaaatcata tcaatataaa aaaatgagta aggcaaatct
    17701 tataaattcc aaaattcacc tcactctatt aaattactct ttatatcctt acccgtcttt
    17761 cctcagacct ttggcctgtg acaaacatag taaaggttgc tttgcagaca tttctgccct
    17821 cttgattggt gatatccaca tccatcacac aggttgtacg accttgatgg acacattctc
    17881 ctttaatggt caatacatcg tcgagttttc ctgccttaag gtagttgata gaggattgga
    17941 gtgtcacccc atcaagtccc agcgagataa ccaccaaacc actgatttgg tcacatagtg
    18001 tgaatagata gccaccatgg gcattgccat agtagttgag cgacgagttc actactttgg
    18061 tcgtcaccac aacgtgacca tctctcattt tttcaatttc gtaattttca aaggcagata
    18121 tagcgtcaaa atgaaagtct ttcatcgttt cctcctgata tttcaaatga cactatgata
    18181 ctacttttta taggactgtg caaggagaaa gctcctagtc tagtaaaatt ccgacatgtt
    18241 ccacaaagcg cataaaggct gtctgccctt gttctgtctg cttgtagact cctgcatcct
    18301 caagtacacg cgcaaagata gcacccacag agtccttgac gattgcaagg gctttttctt
    18361 tatccgttag gtctggatgt tgggatttga gttggtctgc ccactcctga tgataatcgg
    18421 caactgtaac agcttctcct acaagatagc tagcgacttg ctctacttct tctttcagac
    18481 gtggtggcaa gattgccaag cccatgacct caatcaagcc gatattttcc ttcttgatat
    18541 gttggacatc cttgtgggga tgatagatgc catcaggatg atctgctgaa gtctgattgt
    18601 ctcgcaagac caagtccaac tcaaactgtc catcacgctt acgcgctatt ggtgtgatgg
    18661 tgtgatgcgg tgtcccgtct gtctctgcta aaatctgcac actagaatct gaatactgac
    18721 gccattcctg gaaaatctta tcagctaagt taatcaaatc ctctttggaa tccgaagtca
    18781 agcgtaggac agacattggc cacttgataa ttccagcctt gacctgctca aaaccagcaa
    18841 atcggaaggt cttttgcaag ggagccaatt ccataggaaa tacgtgacgg cctccctgat
    18901 aatgatcatg agttagaata gagcccccca caatcggcag gtcggcatta gatccagcaa
    18961 aatatcctgg aaactgctct acgatagcca acagacgttc aaaactctga cgactaatgg
    19021 ccatgggacg atgctggcca tctaaaaaga tacaatgctc attaaagtaa gcatagggcg
    19081 aatactggaa accccattcc tgaccaacca tttcaaaacg gataatccgg tggttgctgc
    19141 gagctgggtg gttgacccga ccatggtaac cctcattctc taaacaaagt tgacactgag
    19201 gataattact agcttgcacc aacttggcta ccgcaatctc tttcggatcc ttttcaggct
    19261 tagagagatt gatggtaatt tcaagttctc cataatcaga tggaacacga taaacgatat
    19321 ttttagcaat ggccttgagt ttgatgtagt catttttctg actgagttga taaaaatcct
    19381 ctatcgcttg ctcaggagag taggcatagg cttcccagaa gtcacgattg acctgactcg
    19441 gacaaggagt caccaagtcc atcaattcag taccaaggat ttcacgcgca gtctgactat
    19501 cctcaatcgt ctctaatcga acggcttcct caactagctg gtccttgagg tcaatcaatt
    19561 tatccagatt ggtctcaact tccaaaacac cttctcccac tcgtgccaaa acacgattgg
    19621 tcaggtagat tcgatccatt tcctcaaatg aactttcaga aatgacatgt gttacaaatt
    19681 tatctactaa ggtcactata gagcctcctt ttgactagtc aaggacgcga gtgccacctg
    19741 caacttcagc gatatagaag cttggagcgt atccaactac ttcctcgtag tgtttgccta
    19801 cagcttcctt aaaggcctca acagtatctt tttgaaccaa ggcaatggca cagccaccaa
    19861 aaccagcccc tgtcatacga gcaccgagaa ctccttcttg tgcccaagct gtgtgaacaa
    19921 gagtatccaa ttccaaacca gttacttcat aatcatgctc cagagaaacg tgtgacgcat
    19981 tcatcaaacg accaaatgtt tccaaatcac ctgcttgaag ggctgcttga gctttaaggg
    20041 tacgttggtt ttcaaacaca gcatggcgag cacgtttcaa acgattttca tctttaatca
    20101 gatagctata ttggtcaacg gcccactcgt ccaattcacc cagggtctga atatccaagg
    20161 caacttgcaa ttcttccact gctttttcac actcagcacg acgttcattg tatttagagt
    20221 ccgccaattc acggcgtttg ttggtgttca tgataacaac gacattgtcc ttcaaatcaa
    20281 gtggcaccaa gtcgtattct aaagtattgg tatctaagta aatagcacgt tggtcagccc
    20341 ccataccaat agcaaattgg tccatgatac cagagttgac tccgataaag ttattttctg
    20401 tttgttttcc gattttaacc aaatcgagac gctctagttt taaatcaaag agatgctctg
    20461 ccacgactcc tgtcaagagc tccaaggatg ctgaagaaga caaaccagca ccatttggga
    20521 tattcccata aacataaaaa tcaaaacctt tgtcaatcac gtgcccagct tcttgcaaga
    20581 aatgaaggac accttttgga taattggtcc agttgtgctc tttttcaaac ttgaggtcag
    20641 cgagaggcac ttcgataatg cccttgtcct caaagttagc tgagtagaaa cgcaagactt
    20701 ggtcgtcacg cttacgagct gcaccgtaag ttcccaagga aatagcagca ggaaaaacgt
    20761 gcccaccgtt gtagtctgtg tgttcaccaa tcaaattaat gcggcctggt gaaaagaagg
    20821 tttggtctgc ttcttgacca aaaacagcaa gaaagtcttt gcgaagggct tcagtagtaa
    20881 gatgttgtgc catatgaatt ctcctttgac tgtccgttaa gccaccttaa cgtataatcg
    20941 ttttctttct attgtatcca aggaattttc caagatcaat cctttttact aaaattttag
    21001 taaaatatca gtaaaaagaa gaaaaacatg atatactaac ctaatcaagg aggatttatg
    21061 gctaccttaa aagacattgc acagctagcc tctgtctcta tcgcgaccgt atcccgcgtc
    21121 ctcaatcgcg accagagcct atctgttaca gaagaaacca gacaccgtat tttaaccgtt
    21181 gctgaagagc tgggctacac caagcacctc aagacaggcg agtcccacaa acccaagcaa
    21241 aagattgcca ttatccaatg ggtcagcgaa caaggggagc tggacgacct ctactactac
    21301 cagattcgcc taggaataga aaaaagagcc caagagttgg actatgatat cttgcgctat
    21361 tttaatgacc atccttttac cttaagcgag gaagtgattg ggattctctg cattggaaaa
    21421 tttagccgag ctcagatttc tgcctttgaa gaataccaaa aacccctggt ctttctagac
    21481 agtgatacac tttctctggg gcatacttgt attattacgg atttttacac tgccatgaaa
    21541 caggttgtcg attatttcct cagccaagga atggaccgta tcgggattct aacaggcctt
    21601 gaagaaacaa ctgaccaaga agaaatcatt caggataagc ggctggaaaa tttcagaaac
    21661 tacagtcaag caaaaggaat ctatcatgat gaactggtct ttcaaggaaa ctttactgcc
    21721 cagtctggct atgacttgat gaaggaagcc attcagaact tgggagacca actcccacca
    21781 gcatttttcg cagccagcga tagtttagct atcggtgccc ttcgtgccct ccaagaagct
    21841 ggaatcagcc taccagaccg tgtcagcctc atttccttta acgacaccag cctgaccaag
    21901 caggtttatc ctcccctctc cagcatcaca gtttatactg aagaaatggg gcgagcaggt
    21961 atggatattc ttaacaagga agtcctccac gatcgcaaaa ttcctagcct gaccatgctg
    22021 ggaaccagac tgacattaag agaaagtacc ctaaatcaag aataggataa cataaaaaac
    22081 gaatagagtt ctaaaactcc tattcgtttt ttattcgatt acaatcatag acttaatggt
    22141 cttacgttca tccatatctt tgtaggcttg gtcgatatct tccagtttat aacttgaagt
    22201 aaagacgcga cctggattga tatcaccatc aaggacggct tttagtaaaa attgcttatc
    22261 gtatgttgta gcagaagctg ccccacctgc tacagagata ttttgcataa atgtcgaacc
    22321 aagagcacga ttattatagt gtgggactcc tacaaagccc atacgccctc cattatgaag
    22381 aacacctagc gcctgttcta tagcagcctc cgtaccaaca cattcaagtg ctgcgtctgc
    22441 tcctccaccg aggatttcac gcaccttggt aattccttct tgaccacgtt ctgcaacaac
    22501 agctgtcgca cctgactcca tagccatctt ttgacggtct tcatgacggc tcataaggat
    22561 aatttgtgat gctccacgca tcttagccgc gatgacagca cattgaccaa cagccccatc
    22621 accgataaca acaaccttgt cccctttttg aacatttgca acacgcgccg catgatagcc
    22681 tgtcggcatg acatctgcaa gagtcaaaag ggactggagc atcccttctg tatagtcaga
    22741 aggttgacca gggattttaa ccagcgccca gtttgcatag tggaagcgaa tatattctgc
    22801 ctgaaaatca ccccccaaat tattgccaat atgattgtcg caagaaccgt caaatccagc
    22861 aagacaggca tcacactcac cacatccatg tgtaaaaggg acaatcacaa aatcacctgg
    22921 tttcaccgtc gtaatggctt ccacagcttc ttcaacaatc ccaatcgctt cgtgtccact
    22981 atttttgtgt ccagctttcg tttctggatt acggtacctc cataaatctg aaccacaaac
    23041 gcacgcacga accacacgaa taatcacatc atccgcttct attatttgcg gacgttcaat
    23101 gctagcaagt ccaacctgac ctgcctttgt atatactgct gatttcattt aaaattttcc
    23161 ttccttataa agtttaattt tgagatttaa acgatttaaa gctgtctgta gctgagacaa
    23221 gcgctcctct aatttttgct tttcctcttc taaaatacca agcctctcct ctctcgtttc
    23281 atctcccttt tggtagagcg acatatagtc aactaaacta tctacagaga cacccgccga
    23341 acgaaaacac ttaataaatt ccagcgcttc gatatcctga tcttgaaaat cacgaatccc
    23401 agtagcagta cgagtaatcg gtggcacaag accaacccgt tcataatacc gaatcgtatc
    23461 cgctgaaatt cccaacaaat cactggcaga tttaatattc acacgctaac ctcctctcat
    23521 ttcattcact gaattcacgc tattctaact cacttatctt attatataac tttgagttga
    23581 ctccaagtca agcattttgt atctaatcga aaaattttta tcattaacaa tcatatatct
    23641 ggagtttata caatgctctt ctcttaccaa tttttgaaat atttaaataa taaagaaatt
    23701 actctattcc aaataagata gtacccaagt atttttcact tttttctaat gttgatgctc
    23761 ataactccgt tccaagtcac acacctttcg cttatgggtt tggtgagttt ctaggtcagc
    23821 atcaatttca atggtaatat tttgaaaacc acaatctttt aggaaaattc gaatagactc
    23881 tttacaagtt tccatatgtt ccatttcttt tagacaaaca tggacaatgg catttttttc
    23941 caaagcatcc atagtccaga gattaagctg attaaggctg gccacattgt ccaatcgctc
    24001 caggccactc tttacttgct tgatatcaag accttctggc acagcatcca agaaaatctt
    24061 gagtgtagac caaaaacgtg gaagggcttt tgaaagaata aagaaagaaa tgacaaggga
    24121 caaaagagga tctaggatat accagtccgt aaatcgaaga acaatcgcca tcaggataac
    24181 agctacccac cctagcgtat cttccagaaa atgcagactc agaatagact cattctttgt
    24241 ctttccctta ccaaccacca gactcgctaa cagattgata gtaatcgcaa taattcctaa
    24301 ccagagaatc ccctcatcat tgactggttg cggatgcaaa atcttcgtga cattttccaa
    24361 aatgactaga acagagcccg ttacgagaat cacagctgtt accaaggctc ctagcaggct
    24421 aaaccgctta tagcccaagg tgtactgatt gtcttcttca cgattggaga ttgtttctag
    24481 aaaagctgat attccaattg caatcgcatc tcccaagtca tgcacagagt cagcaagaac
    24541 agcgctagaa ccaaatactc cacctgcaat aaactcaaca atggcataag tcaaatttaa
    24601 gaaaaaagcc acccaaacag catattttgc cttcatattt ctcattcctt tgttataata
    24661 gatttatgaa caccttgttc attatcatta tccactaaaa ctcaaagaaa ggatagaagc
    24721 aaaacgtcag ctttattcag ttctgaacaa tttgccttaa gtgtccatat gactaacatt
    24781 gaccgccgta tcagcaaaac caaaaaagcc atctatcaag cttttataca acttttgaat
    24841 gctaagggct acgaggccac tactgttcag gatatcattg atctcgcaga tgtgggacga
    24901 tccacctttt actgtcacta tgagagtaag gagcttcttc tggaccagct ctgccgctac
    24961 ctcttccatc atctttttga aagagagcaa gccatttcaa ccgaggacta cctcgcccac
    25021 ctctttctcc attttcataa aaaccaagac catatcacca gtctgctatt ttccaaaaat
    25081 gactacttcc tccgtcaact ccataaagag ctagaacacc atgtctattc cgtgctagct
    25141 gataatttaa aagaagccca ccctaatctg cctacttctt acctccaaca cttggtcatg
    25201 tccaacttta tcgagacatt gacctggtgg ctcaaaaaag gtcaagattt cacagaccag
    25261 gaagttgtcc aattttatct agaccttctc attcctaaaa attgaatata gagtaaagct
    25321 tcagttgtct tatttctagg ttactgagtt ttttatcttt tcaacaacaa aagaggaccc
    25381 gccgatcctc tttttcatac tataaatcct tgattatcaa ctatatctgt tttaatcgaa
    25441 atctcaaaac agcactttca aacatctttt cctagttaag taaatcagta ttctgcttag
    25501 ctgccttgct ccattgatac caaccaacta gactgttaat gagataaatt agatatttcc
    25561 cttgaatttg caggctttct ccccaccaga gatagattga aaagacattg gtagccgccc
    25621 agaatatcca ctgttcacgg taaacagctg tcatgaggat ttgccctacc ccattggttg
    25681 catctgtgat tgaatcacga tagggacgat tggcaccaat agactgataa atgaagccaa
    25741 aggccaacca ccaaagcaca ctaatggaaa gatactttgt ccagcccttg ccgtccagtt
    25801 tacgcgcgac aaactcctgc ttttccttct taaactgtgc ctgataaatc caaactagaa
    25861 gtccaattgg ctgcatgact gtgaagtaaa gtgtcgtcag cacctcacca taaaagcctt
    25921 tctgtagggc caaaataagg taaataacag agttaatcaa gccaaaaaga taattacttg
    25981 ctcgaccttc cgatacaaag attacacaga taatccctgt caagctacaa atcatcccaa
    26041 tccagtcaac aatacgatgt tcgtaaacca actccagcca gagaggaaaa cttcctaaaa
    26101 ccagcaaata aatccactgg gcaaaactac gatgggcaaa gaggtcatcc cagatagcct
    26161 tcatagttcc tgaaaatcct aaatcagcca tagccgcaac catacgacgg taaccacctg
    26221 acatttcacc tagggttgtt ttgatatttt caattttctt ttgcaaataa gtatgcatca
    26281 tttctccttt tgtttttaaa gagccgtgtc tggatagact ttcggacgca acgctctatt
    26341 agataatgaa ctgcctatac acaagatttc taaccttagt cgacatgagc tgaaacctct
    26401 tatttgttaa gtagttcaca aaatattata cacctatttt atgaatagtc aactgtcttt
    26461 acagtaaaat tttagaaaat catgaaaatt ttctctttct ttccatttta agtgacattc
    26521 agtcattctc acatcaaaaa agcccagacg aaattgtctg agcattcttt tatctagtcg
    26581 tttaaggaag ttgagttcag tatgtttaaa gtctctgtcc catcatttct tcaacaaacc
    26641 ttgttcttgg agaaactcct tggctacttg ctttgctgac ttgccttcaa caccgacttg
    26701 gtagttgagc tggctcatct ggctttctgt aatcttacca gccaatgtat taagaactct
    26761 ttccaactct gggtgtttct tgagaagagc ttctttcatg agtggagccc cttgataagg
    26821 tgggaagagt tgcttgtcat cttccaagac ctgtaaatca taacgctcca attccgcatc
    26881 agtcgaatag gcatccgtga tttgaatatc ccctgactga atagcctgat agcgaagggc
    26941 tggctccatg gtcgctacat tgagattgag accatacatt gattgcaagc ccttatttcc
    27001 atcttcacgg tcgttaaact cgagtgtaaa acctgccttc aactgccctt ccactttttt
    27061 caagtctgaa atggtcttca agccatattc ttgagcaatc tttttcggaa cagctacagc
    27121 ataggtgttt tgataagaca tgggtttgag ataggctaga tgatcctgct tagcaatgcc
    27181 atcacgcgcc acctgataaa cctgttctgg ttcatgactc accttgggtg atggttgaag
    27241 caaactttca gtcaccgtac cagtaaattc aggatagatg tcaatatcgc cttttttcag
    27301 agcttcataa aggaagcttg tcttcccaaa attcggttta acagtcgcag tcatgctggt
    27361 attttcttca atcagcaact tatacatatt ggccaaaatt tctggttctg gacctatttt
    27421 cccagcaata accaagtttt ccttctcttt ttgaaccaaa agagctggac tataagacag
    27481 acccagtaat aaagccacca aggcaaaacc tgagaaaatc gtccgtaatt ttgctttttc
    27541 catcactttt agtaggaagt taaaggcaat ggctagcact gcagaagaaa gtgccccaat
    27601 caaaatcaaa ctggcattat tacggtcaat tcccaaaaga ataaaggaac ctagtccccc
    27661 tgcaccaatc aaggccgcca aggttgccgt accgataatc aaaacagctg ccgtccgaat
    27721 cccagacatg ataacaggca tggcgagtgg aatttcaaat ttcttgagac gttcccatct
    27781 ggtcatccca aaggcaatcc cagcctcttg caggttcgga tcaattccct tcagcccagt
    27841 gatagtattt tgcaaaatag ggaaaatcgc ataaatcact agagctgtca aagccggcaa
    27901 ggtcccaatt cccatcaaag ggataaagag ccccaacaag gccagagacg ggatggtctg
    27961 gaaaatacct gcaatctgca agacccagtc ggccagcttc tcatgatagc gaagaaaaac
    28021 agccaaggga atcgcaagca aaatagctag taacaaggtc aaaagcgaca actgcaaatg
    28081 ttgagataga gctgtcaacc aatcactaaa acgatcctga aaagttgcaa ttaaattagt
    28141 catgaacact acctccaaac aagtctgcta caaagtctgt tgcaggcgct tttaaaattg
    28201 tctcgggatt cgctacctgg cgaatttctc catcctgcaa gacagcaata cggtccgcca
    28261 acttcaaggc ttcatccgta tcatgggtta caaaaatcgt tgtcatccca aactctttat
    28321 gcaattcttt tgtcagaacc tgcaactgtt ttctcgaaat agcatccaag gccgaaaagg
    28381 gttcatccat gaggaaaatc ttgggctgac caatcatagc tcggacaata ccgacccgtt
    28441 gctgttctcc accagataat tcactaggta agcgatgccc atactcggct actggtaaac
    28501 caaccttagc caaaagctct tctgttttct tcgtaatttc ttccttgctc caccccttca
    28561 tttcaggaat gagagcaata ttttccgcaa ctgttagatt tggaaaaaga gcaatagcct
    28621 gtaaaacata accagtagaa agacgaagtt cacgctcatc atagtctttg atgcgcttcc
    28681 catccatata aatatttcca tcagttggtt ccaaaagacg gttaatcatc ttgagcatgg
    28741 tcgtcttacc tgacccagaa ggccctacta aaaccataaa ttccccatcc tcaatctgta
    28801 agttgacatc tctcaagaca tccttttctg tgtagcgcag tgctacattt ttgtattcaa
    28861 tcattctttg tcctcaattt aaaacttccc tcgattggtc aagtcttcta ccttaggcat
    28921 aacttcctta ttatcccaat gctccacaat tttcccgttc tctaaacgga agatatcgta
    28981 ctgggcataa gcaacgccat caatctgagt ctgaccatag ctaaccacat agtttccttg
    29041 tcctaagagt tggaaaacaa agtcaaaagt gacactatat tcagccacat agtttttata
    29101 agcagcactt ccttgtccaa tatcatgatt atgctgaatc aaatcgtctg ccacataatc
    29161 actccactgc tctagctccc cattttggaa aatttctgtc aagaaacggc gaaccagctt
    29221 tttattttct gctttcttgt ccaaatcctt gatttcaaaa tctccaaaaa tttgatctag
    29281 ttggtcattt tcaggtgttc gatagtagtc aacgacatcc caatgctcaa caatacgacc
    29341 attctcatcc gcacggaaag tatccgtcgt cacccattga gcttctccac cattcagata
    29401 ttgatgaaca tgaacaaaga ccagattgcc atcctcaatg gtgcggacaa tcttaatctg
    29461 acgctctgga tgacgctcaa agaaatctgc aaagaaggct gcaaatcctt ctttcccgtc
    29521 aggaacacct gtcgaatgtt ggatataggt atcccctaca gactgggctt gagcctcagc
    29581 aactcgcccg tcttgaatgg catggatgta taggttgtga gcatttttca cttgttgtga
    29641 catattctaa acctcatttc ccttctcttt cagattcgcc aaaattcttt cttgaaaacc
    29701 ttcaaattgg tgaatttctt cctctgaaaa tcctttgtaa aagatagtat ccaatttctg
    29761 actgacacga tgccccactt ctttctggaa cttgcctaac tccgttaaaa ctaaatactt
    29821 cttacgcttg tcttttccac acggactaac aattacaagc ttttgttcct ctagcttttt
    29881 tatcatagtc gtcagcgtat tattcgcaag cccagtcgca agcgcgatat ctgtcgcagt
    29941 tgcgcagcca gtttcactat tccataaaac cgctaaaatc ttgccctgtt cacccctata
    30001 aagagcctca ggatcttgac tcagtaactt ttgaaaaatc cgcccattca acaaacgaat
    30061 atgatgggct agcaaatgac tatctttcat aacacctcca atttatttcg atatcgaaat
    30121 gaataaaata attgtaacac tcatcgttct aactgtcaac tatttcgatt tggaaataat
    30181 ttttgataat tatccacacc accatactcc ggctcaacta acttttaacg agagtttcta
    30241 aactccttcg tcctccagtc tacaaaagcc ttccattcgt actatcctat attttatgag
    30301 gggacacatt tttcctatca gaccatttat tttaaagata gaagtaaatc ataattgctt
    30361 ccatctgttc ttttatagta tattgaagtt agactagagc actgtatctt ctaaaacatt
    30421 gatagaaagc gatttgaatt tcccaatcaa tttgttcgta tttatagcat tttgaaacta
    30481 gaataggaca ccatgactgc taaaagattt ctataaattc atttgatttt cctaatcaat
    30541 ttgttcatat cttatttcat tccgctataa tttcacctta ccctatcttt ttcgtagcac
    30601 ccttcaaaca gcctatcccc taccgtttga cgattcctca cttcgctcca cttccattac
    30661 agaagtttct tcactactat gggctcggct gacttctcat gattccttgt tactactatt
    30721 tgaacgctca cgagatagat cttacaaaaa atgctttgat ccacaatgga atcaaagcat
    30781 tttaaagagt tcctcataca taagcgcaga agtcgcagtt cctctgtact tggcttcttc
    30841 tcttttgata aagcgagcca agttgagcaa ctcaggtgct ggatgtttgg gatttaggag
    30901 caattcacga ttgaccaggc ctgagagacg aactgcctgc aattgctcat ttgtagtagg
    30961 cagtttttta gcagtctcta ggagagcagc aactaaatct tcactcaaat catgtcgagc
    31021 atgattgtaa agatctttta taaggctttc taggtttggt tctgccatcc ctaccacctc
    31081 ccttatggtt taataatgtt taatcaaatc aaccgttgaa cgatccaatt tcttcaccaa
    31141 ggcttgtaag aaagcttgcg cttctaggaa gtcatccatt gcatagaggg tttggtgaga
    31201 atggatataa cgagcgcaga caccgatagt tgttgatggg acaccaccat ttttcagatg
    31261 agctgcacct gcatctgttc cgcctttacc acagtagtat tggtacttga taccagcttc
    31321 ttcagccgtt gtcaaaagaa aatccttcat ccctgggaga agcaagtgac ctggatcata
    31381 gaaacgaatc aaggttccat ctccaatctt gccttgacca ccgtagacat cacctgctgg
    31441 tgagcaatca actgcgagga agacttctgg gtcaaacttg gttgtagagg tatgagcgcc
    31501 acgcagacca acttcttctt ggacgttaga acccagatag agttcattgc cgagtttttg
    31561 acctgataaa gcttcagcta gctcgcttac catgaggaca ccgtagcggt tatcccaagc
    31621 ttttgagatg atattttttt cattggctgt caaaattgca gaactatctg gtacgatggt
    31681 atcaccagga cggatgccaa aactttctgc ctcagccttg tccgcaaaac caccatcaaa
    31741 aacgatatcg gcaatggctg gcatggttgg tccccccttt ccacgagtca aatgcggagg
    31801 aacagaacct gaaatcacag gaatttcatg accatcacga gtcaagagtt tgaaacgttg
    31861 gctgctaacc accatggggt tccagccacc gatttctacg acacggaagg taccatctgg
    31921 cttgatttcg ctgaccataa aaccaacttc gtccatatga gaagcgacca agacgcgcgg
    31981 tgcatccaca gcttctgaat gtttgatacc aaaaatacca cccaagccat ctgtcaccac
    32041 ttcatccaca tgcggtgtca acttttcacg aagataagca cggacaggcg cttcatgacc
    32101 tgagactgca gcaagttctg ttacttcttt aatttttgaa aataatgttg tcatttcagt
    32161 tccttctttc tttcatccat tttaccactt tttataggag aaggatagtg ggaaggtgga
    32221 tttctaagtt agtatcttag tcctgctcta tcttagaaaa ggatagtatt ctcttgcatg
    32281 tagtgcaaaa tctagtaaac attccaaaat taactcgaat atttatttcc aaacaaaaaa
    32341 acaatacacc atcaaagttg tttgtatttt tcatgaaatt tacagaaaat agttgacttc
    32401 cctttcttct ttctttaaat atatagttgg ttgagtttgg aatagtacgc tgtagctgct
    32461 gaaacatttc tagaaattaa tttgactttc ctaatagagt tgttcatatc ttatttcaat
    32521 ttactatagt acaaaactag aaaaggaaaa aatcatgacc aaaacaattc ttgttacagg
    32581 tgggactagc tacattggct cccataccgt taaagctctt ttaaatgctg gctataaggt
    32641 gcatgtcctc gataatctct ccacaggaaa tcgagcggct gtggatagtc gtgctagctt
    32701 taaagaactg gatgtttatg atgctagcgc cttaaaggct tacttagaag aaaatcagat
    32761 tgatgctgtc ctccattgtg caggtgaaat tgttgtgagc gaaagtattg aaaatccaag
    32821 taaatacttc actgccaacg ttgctggtat gaaccaagtt ctcaaagtct tatctgaagt
    32881 tggcattcaa aaaatcatgt tctcttcgac tgcttctctc tatggaaata actgtattga
    32941 caagccagtg actgaagata ccctgctcga ccctgtcaac ccttatgcag agacaaaact
    33001 gatgggcgaa cgaatgattt actggatggc caatcgctac gactggaaat atgttatttt
    33061 ccgttacttt aatgttgctg gggctgaaat ggatgcttca aacggtctgc gtgtgaaaaa
    33121 tccaactcac atcattccaa atatcaacaa gaccgcattg ggacaaaatg atagcttaaa
    33181 aatatttgga gatgactacg atacacgtga cggttcatgt attcgagatt acatttatgt
    33241 cttggacctt gcataggctc atgttaaagg aatgaactac ctatttcaag aagacagttc
    33301 ttctcaaatc tttaacttag gaactaaaaa aggctatact atcaaagaaa tctttaaaac
    33361 tgctgaagaa ttactaaatt aaaaaatccc acacgagatt gttgctcgac gtgctagtga
    33421 cccagccagt gtcctagcag atgcttcaaa agctaaacaa tatcttgatt ggacggctag
    33481 ctactccctc gaagatatta ttttatcaga ttaaggtaaa aacattttag aataggataa
    33541 caaaggagaa agtcttgttg ctctctcctt gttgtattta ttaaattgtc agaaatttta
    33601 ttgacagatt agaaaaataa tgttacattt atatccgcag atatctttcg ataccaaatc
    33661 tacatgaaag gacggggtat gaaactttct cattatttaa ttggcttact tctactccta
    33721 gtctttctct ctattagcat tgggaccagt gatttttcat ggggaaagct atttgatttc
    33781 gaccagcaga catggctcct ctttcaagag tcccgtctcc caagaactat cagtattctc
    33841 ctgactgcct ctagtatgag tatggcaggc cttctcatgc agactattac ccaaaatcag
    33901 tttgctgcac cgagtacagt tggaacgact gaagccgcca aactgggaat ggtgctgagc
    33961 ctttttgtct ttccatcggc tagtctgacc caaaagatgc tcttcgcttt tgtttcatcc
    34021 atcgtattca ccctcttctt cctagccttt atgaccattt ttactgtaaa ggaaaggtgg
    34081 atgttgcctc tgattgggat catctatagc gggattatcg gctcagtcac agaagttatc
    34141 gcctatcgtt tcaatctggt tcagagtatg actgcctgga cccagggctc cttctccatg
    34201 attcagaccc atcagtatga gtggctcttc ttaggcctca tcatcctgat aaccgtttgg
    34261 aaattatccc aaaccttcac catcatgaat ctggggaaag aaatcagcga gagtttgggg
    34321 atttcctact ccctacttga aaaactggcc ctctttctgg tggcgctaac gacaagcgtc
    34381 accatgatta ccgtgggtgg cctaccattt ctcggagtta tcgttcccaa tcttgttcgc
    34441 aagcgctatg gagataatct aagtcaaacc aaactcatgg tcgcactggt tggtgccaat
    34501 ctagttctgg cttgcgatat cctatcccga gttctgatta ggccctatga gttgtctgtc
    34561 agtctcttgc taggaatcat cggtagtctc ggctttatcc tacttctctg gagaggggga
    34621 cgaaaagatg cagactaaaa gcaaacatac caagctcttc tggattctca ttattcttgc
    34681 catcggagct tgtcttctct acttttggcc catcactcac ttgtcagcct ttgcttggaa
    34741 gttgcgttcc caaaagatca tcgtttatct cttggtagcc atcgcgactg ggatttcgac
    34801 cattagtttt caaaccctga cggaaaatcg cttcctgacg cctagtattt tgggaattga
    34861 atccttctac gtcctactac aaaccctact actggttttt gaaagcaagt ttcttcaact
    34921 tggcaaatcc cctatcttag aattcctagt cttacttctt gtccagtccc tcttctttct
    34981 caccttacaa ggttacttga agacactgat gaagcaagac ctggtcttca tcctgctgat
    35041 ctgtctagcg ctcagaagtc tctttcgaaa tatcagcacc ttccttcaag tcctaatgga
    35101 tccaaacgaa tacgataaac tgcaaaatag tctttttgcc tcctttcaac atctcaacac
    35161 ttccatccta gccatcggtt ctctgatcat cctcgctttg acaatctttt tctttcgaaa
    35221 agcagtcgtt ctagatgtct tgcacctgca aagagaaacg gctcagatat tgggactcga
    35281 tgttgaaaaa gaacagaaag agctcctctg gggaatcgtg cttttgacct caacggccac
    35341 tgccttggta ggacctatgg ccttcttcgg ctttatgctg gccaacctca cctacctgat
    35401 tgtcaaagac tatcagcaca agttactctt tatagtggcc attctggttg gatttattag
    35461 cttaaccttg gggcaagcct tgattgaacg agtctttgca ctggaaattc gtatcagtat
    35521 gatcattgag agtgtgggtg gcttcttatt ctttatctta ctatatagga ggtctcgtca
    35581 gtgaaactgg aaaacattga caaatccatt caaaaacagg atattttgca aggcatttcg
    35641 cttgaagtca gtcctcaaaa actgacagcc tttattggtc caaatggtgc tggaaaatcg
    35701 actctcctct ccatcatgag cagactaacc aagaaagatc agggagttct cagtatcaaa
    35761 ggacgtgaaa tcgagagctg gaattcgcaa gaactggccc aagaactaac catcctaaaa
    35821 cagaaaatca attaccaagc caaattgact gttgaagaac tggtcagttt tggacgtttt
    35881 ccctacagcc gaggtcgact tagatcagaa gactgggaaa aaatccgaga aactctgaac
    35941 tatttggaac tgaccaactt aaaagaccgc tacatcaata gcctgtcagg ggggcaactc
    36001 cagcgcgtct ttatcgctat ggtactggcc caggatacgg actttatctt gctggacgaa
    36061 ccactcaaca atctcgatat caagcaaagc gtcagcatga tgcagattct tcgacgactg
    36121 gtggaggaac tcggcaagac cattatcatc gtcctccacg atatcaacat ggccagtcag
    36181 tatgcagatg aaattgtcgc cttcaaggac ggccaggtct ttagcaaggg aagcaccgat
    36241 caaatcatgc aggctgacct gctcagtcaa ctttatgaga ttcccatcac gctagctgat
    36301 atcaatgaca aaaagatctg tatctatagc tagtaacata aaagctcaag ttagagaacc
    36361 ttcagtctct tagtcaataa gattaagaga ctccctaaat cgttatcaca ttttaaaaag
    36421 gagaaattat gaaaacatcc cttaaacttt atttcactgc cctagtggcc agcttcttgc
    36481 tcctacttgg tgcatgtagt acaaactcaa gcactagtca gacagagacc agtagctctg
    36541 ctccaacaga ggtaaccatt aaaagttcac tggacgaggt caaactttcc aaagttcctg
    36601 aaaagattgt gacctttgac ctcggcgctg cggatactat tcgcgcttta ggatttgaaa
    36661 aaaatatcgt cggaatgcct acaaaaactg ttccgactta tctaaaagac ctagtgggaa
    36721 ctgtcaaaaa tgttggttct atgaaagaac ctgatttaga agctatcgcc gcccttgagc
    36781 ctgatttgat tatcgcttca ccacgtacac aaaaattcgt agacaaattc aaagaaatcg
    36841 ccccaaccgt tctcttccaa gcaagcaagg acgactactg gacttctacc aaggctaata
    36901 tcgaatcctt agcaagtgcc ttcggcgaaa ctggtacaca gaaagccaag gaagaattgg
    36961 ccaagctaga caagagcatc caagaagtcg ctactaaaaa tgaaagctct gacaaaaaag
    37021 cccttgcgat cctccttaat gaaggaaaaa tggcagcctt tggtgccaaa tctcgtttct
    37081 ctttcttgta ccaaaccttg aaattcaaac caactgatac aaaatttgaa gactcacgcc
    37141 acggacaaga agtcagcttt gaaagtgtca aagaaatcaa ccctgccatc ctctttgtca
    37201 tcaaccgtac ccttgccatc ggtggggaca actctagcaa cgacggtgtc ctagaaaatg
    37261 cccttatcgc tgaaacacct gctgctaaaa atggtaagat tatccaacta acaccagacc
    37321 tctggtatct aagcggaggc ggacttgaat caacaaaact catgattgaa gacatacaaa
    37381 aagctttgaa ataagccact tcaaactcaa tttaatactc aatgaaaatc aaagagcaaa
    37441 ctaggaaact agccgcaggt tgctcaaaac actgttttga ggttgcagat gaaagctgac
    37501 gcggtttgaa gggattttcg aagagtataa aattttgaca ttctaaaacg catcctatca
    37561 agttcactca aacctgatag gatgcgtttt tatcattttg aaatctattt accccacctc
    37621 attccccttc ttgatttcgt ttaagggaaa agtggtctgg aacggggtcc ttacctgttt
    37681 tcgaccaggg atgacaacgt aaaatccgag ccaagcccat caataccccc ttaaaaccat
    37741 gtttttcaat agcctgaatc atgtagttgg aacaagtcag ctcaaagcga caagagggtg
    37801 gaaagactgg tgagataaaa cgttggtaaa agcgcacagg cgctattaaa attcgtttca
    37861 ttatttctta gttacagcca tggtgtgtag ttggctgatt tcttttttat taagacgacg
    37921 ggattctcct ggacggagtc ctgtcaagtc taggtgtccg aaacgagtcc gagacaactt
    37981 atctacttgg agaccaacag cttcaaacat ctttttaacc tgatggttac gcccttcatg
    38041 gatggtcaac tgcaccacag agcgattttt gactgggtcc actttgagaa tttcataaac
    38101 agctggcttg gttttcttac catcaatctc aagaccacgg gtcaaggggc ggagattgtc
    38161 cttattggcc acacccttaa cacgcgcgac ataaaccttg tcaatctcat tacgagggtg
    38221 aatcatctcg tctgtaaagt ccccatcatt ggtcaaaatc aagacacctg atgtatccca
    38281 gtccaaacga cccacagggt aaatacgctc tttgacattg ggcaagaggt cgacaaccgt
    38341 cttgcgaccc ttatcatctg tcacactgga aatcacaccg cgtggtttgt taagcagata
    38401 gtagaccttt tcttcgttgt agataggttg accttcaact tcgaccttgt cgcctgactt
    38461 gatagtggtt gctagttcac gcaccacttg gccgttaacc gtcaccaagc cttgcttaat
    38521 cagctcttct gcttttctcc tactggccac acctgcgtgg gcaatatact tattgattct
    38581 catcttcttc tatcctttca ccaaataatt ggctttcttg ggcttgaatc tcaagctcat
    38641 caatcactgg taattcttct aaatggttta tccccatgta atctaggaaa taatccgtag
    38701 tcacatagag gttggggcgc cccaatactt cctttttccc gtcttccttt atcaggtcaa
    38761 aagcctgcaa ctttgccaag gctccactcg agttaactcc acggatggca tcaatttcta
    38821 tccgcgtaat cggctgtttg taggcaataa tggacaaggt ctcaagggca gcccgagaca
    38881 agctctggtt gataggcgcc ttagagtatt ccttcaaaat ctctgcaaat tgagacttgg
    38941 tcaccaatct ataagcacca cttgtctcaa tcaaagccaa actggaatct gggtcctttt
    39001 catacttctg ggctaatttt cctaaactct gctggatgcc tgtcggtggc agagagagga
    39061 gttcagctaa ctggcggacc cgaatcccat cttcacccgc tacaaacaag agcgcttcta
    39121 tttttgctaa agtactcatc tttcctctct atcaagtcta gctttgaggc acttgacttt
    39181 cttccttctt ttccatgaga tagatatctc caaaactctc ctcttgcacg aggatcagct
    39241 cctgggtttt gattaactct agggttgcca aaaagagggt gatgacctct tggacattct
    39301 gggcttcctt gaacaaatcc tgcaagcgca attgatctcg tccaatcaag gactctttca
    39361 cgataatcat catgtcctca atcttatact catcccgcaa gatagtcgtg tgattttgtg
    39421 caaactcctc ttttttcttg gctaggatat ttgaaaaagc caaaaagagg tcaatggtcg
    39481 tcttgtcatg cacaagctcc gcatcttcgt aaatcaactc tgtcggcgct ttggaataat
    39541 actgggcccg ttcttggtgc ttggcttcca agtgctcacc caagagcttg aacttgcgat
    39601 attcttcgat ttgagagagg aggtcctgct ccaggtcatc ccccaagtct gtcacttctg
    39661 ctaccttcgg aaggagttta cgactcttaa tcagcatgag ctgactagcc atgaccatgt
    39721 actcacccgt cacttccaga cgcatggcct gcagggttga aacataggct agatactgtt
    39781 cgatgacttc cgtaatgggc acatcgtaga tatccatctg gtacttagaa accagatgca
    39841 agagcaagtc cagggggcct tcaaaatctt ttaatttaat atccattatc tatatttttc
    39901 taaggtcagg actgttttta atcctaattt ttttgcaatt tcgtacaaat cgaccttgtt
    39961 ttctatttgt cttagaataa actgttcacg taagacttga gctgataagg atggaaaacc
    40021 tttctccttg acaaaagatt ctaactgacg aaaggcccac tgacgagaat agggtttctc
    40081 tcctctttca aaaagatagg tctgccccat caagggttcc aattctgaaa gcaaggccgt
    40141 gggaatggtg acaatcctct gttgggaagc cttgctgatt cgcaacacct gaaaatccag
    40201 attgatgtcc gcaaccttga tggctaaaat ctcactgggc aagagcccca tttctaggat
    40261 taagagcgct agcaagcggc cctctggatg gtcgctttcc tgccaaaaag agtctaggta
    40321 tagaatctct ggcttttccg tcttcttttc agcttgtttg gctaattcca agcggtaaaa
    40381 gctgtccacc tctccttttt gatagagaaa gtatagaaat tggttacagg ccgaaatctt
    40441 tcgcttctgg gcgctgattt ttagattggc tagctgggct tggtaaatct tgagactggt
    40501 ctcagaaatc cgctcaccta ccatgtctaa aaattgctcc aaatcatact tataggactg
    40561 cttggaattg acagacaagc cctgcttttc ctctaaaaag gctgaaatcc tgtctctcat
    40621 tggcatcgaa tctcatattc cttactaaag tcatgcaaga gggcattaac ggccttgagg
    40681 atggacttac gcgtaataat cccttggaaa ataccctctg catccacaac cggtaagaag
    40741 gactcatcta ctagcttgtg caagacctcc gtaatggtga aatcaggcga aacaaccgct
    40801 acgtccgttt ttgtcatatg aacgatatcc gtatccgcca tgatttcttg gctcaagtca
    40861 tgctccatct gataagccat aatatctctg agtccaatcg tcccaacaaa ctgtttttca
    40921 tctgtcacaa cgggaacacg ggtataggtc atctgactga gcaagagggt cgcatgatcc
    40981 gcattgtggg tatcaatcaa cacagctaga tttttagcag gggtcaaaaa agtttcctcc
    41041 tgccccaaca agaaagtctc aaactccttg gcaatcatcg gctaaactcc ttggacaaac
    41101 ctggatacac ctcgtgatct cgtgtcaaaa agtccacttt gaagtaacta tcatcaatct
    41161 ccacacgagc atagagacat tctctgatgg tacctcgtgg ttgactgata gaacctggat
    41221 ttagaaagag gatcttgcct tccaaccaag cacttggcac atgcaagtga ccatagaggc
    41281 agatagcggc ctcttcctcc tgagcccagt agtccaactt ttgaaagttg aaattgatgt
    41341 caaacaagtg accatgagtt tggataatct tggtcgaacc aagctcagtc accagacgtt
    41401 ctgggtagcc ggcgtagaag tccatgtttc ctttaacaac gcggatgccc tcccaaagtg
    41461 gagaatccgg acgtagttca gaatcgccgt tatgaaaaac ggcatcgact ttgcccacat
    41521 agcgatcacg gacttcttcc acaatcaagc tatcgccatg ggaatcgctc attacaatga
    41581 tggtttgctt tgccatgatg gaaatacctc caaaagtttc ttaacggcta aggcacggtg
    41641 agattgacta tttttttctt ccagggttaa ttcagctgat gacttacctg tctctcctac
    41701 aaggaagagg ggatcatagc caaagccatt ttcaccctta ggttcaaagt taatataacc
    41761 tgaccagtct gcttcaacaa ctaaactttc cttatttggg ctggctacga ctagggttgt
    41821 gtggaactga gccgagcggt ccttgagttc aaagaccatg gccaattcgt gcaagagttt
    41881 ggcattattt tcacggtcag ttgctcccac acctgcgaaa cgagctgacc agacgcctgg
    41941 taagccacca aggacatcga ctttgagacc agaatcatct gccaaaacca tcttgcccgt
    42001 taattgagaa atggtttctg ccttaaggcg ggcattttct tcaaaggtca tacctgtttc
    42061 tgctacttca ggcaggtcag ggtagtcatt aagattttcc acatcgtagc ctaacttatc
    42121 aaagatagct cggaattcct tggttttgcc ttcgttacga gtcgcaatca acaaggtttc
    42181 tctgaccttg cttgtctcaa agaaatcatg aacattgacc ccttctttag gcaattctac
    42241 atacaagagt tgcccatttt caaccaagag cagggcccca tgacgttgaa taacttccaa
    42301 gtttcgtccc atttcttgat taagcatgtc taccacaaag gagaacaaac ggtaggtaga
    42361 accatagcgt aaaacagtaa ctgaaagcgg gaaaccatac tcttcatctc caaatatttt
    42421 ggagaattca aacagaggaa aatctgtctt atagtcgctc aaactgttaa cgccaccaaa
    42481 aatactataa gacccaacat accaatcctg gtcatcctta tattcataaa ttttatttgt
    42541 cataattcta catgctccac ataaatctct ttttccagcc attcttcacc aatttgtgca
    42601 aaactttggc tactggctgt tgtgtaaaaa cggtgatgga gtggtccagc atcgcgacca
    42661 cgattgattt caaaataatt gagtaagact gagatatccc gtacgcactc tgccccacta
    42721 tcgatgagct gaacctttgg ccccatgaca ttttggataa tagggcgaag gagtggataa
    42781 tgagtacagc ccaaaatcag gctatccacc tttccaacca agggacgcag ggtttcatag
    42841 accaccttct tggtaacact ggttgacagg gcacctgact caaccaaggg agcaaacttg
    42901 ggacaggcca agctctccac ctgtaagtcg ggatccagat catggatttt ctgacggtat
    42961 atgtctgatt gtaccgtcat gggcgttcca atcactccga ttttcccacc ttgactggac
    43021 ttgatggctg ccgaagctcc tggcaaaatt acacccaaga caggaatatc tagttgagcc
    43081 ttgatttctt cccagacgac cgcagtcgca gtgttacaag caatgacaat cattttgaca
    43141 tccttggtca agagaaagtt gaccagctgc caagtatatt cacgaatttg ctcagctgga
    43201 cgggggccat agggcgcccg cgccgaatct ccaatataga cgatttcttc atggggaagc
    43261 tggcgcatga gctcgcgcac aacggtcaag cccccgacac ccgaatccaa aaaaccaatt
    43321 ggtcgattat ccatacagtc ttctttctag tcttttttct gattgatcgt tcattatgat
    43381 tccttgtact gaacgaactg accgacagct tgatagaatg tcaactacct ctctcttaat
    43441 cataatcaaa tatcaataga atgcaaggaa aaagtctcat ccctaaacca taaccaacat
    43501 agtgagaagt ctggaacttt catcccagac ttttccttat ttattttttc tttttattgt
    43561 tagcaagggc tgccttttgt tggcggatga tttggtggta aacttgttgt accttagctt
    43621 cgcttggttt ttgaccattt gcactcaaaa gagtacgaac tgcttcagca ttcaaacgtg
    43681 ggttgtcagc aaattctttt tcgatttgct tacgaaccaa gtacattcct ccaagagctc
    43741 ctcctagaaa agctagcaca atcaatacaa ttgctaaaag taaatccatc atttttctcc
    43801 tgtttctttt tgagtccctt tcattatacc acaaactagc caccctgacc agtttgttct
    43861 acactttcag ggatggaata gacagcaaaa agaaccctgc ttttctgaaa aagaggtctc
    43921 cttgctaagt ttaatttaca taaatagcca gtgtttgata gggttttagt agaattttct
    43981 cagacacttc tgcatcttca tagtttgaaa tcaaaatctg tccattttgg tagactgctg
    44041 gcaagtcgat ttccacttct ttagcataaa agttattgag cactagtaac ttttgatcct
    44101 caaactggcg ttcaaaagcg tagacttgtt tgctatcttc aaaggctggt ttgtaacttc
    44161 cttctgaaat gattggcatt tccttacgca gtcgaatcaa gtcttgatag aaggtaaaaa
    44221 tcggaccctg gatttcattt tctacattga tgtctttata ggatttacca gctttcaacc
    44281 aaggagtgcc tgttgaaaat cctgcatttt ccgaagcatc ccactgcatg ggaatgcgtg
    44341 aattatcacg cgacttagct tgaataatct ggaaggcttc ttgctgactc tttccttctt
    44401 ctaggagcat ctgataggca ttaagcgatt cgacatccac gtaatcagcc atagaatcat
    44461 agtctgggtc aatcatcccg atttcctcac ccatgtagat ataaggtgtc ccacgtgaca
    44521 ggtgaatgct ggctgctagc atggtggctc cttccttgcg gaagttttga atatcgacaa
    44581 aacggttcaa ggcacgtggt tgatcgtgat tgttccaaaa gagggcactc caaccgtctt
    44641 tatcactcat ttccttaccc caactatggt aaagactctt caactcttca aaatcaaagg
    44701 gagccaaggt ccacttttgt ccatccttat agtccacctt gaggtgatga aaattaaagg
    44761 tcatggataa ttcctgacga tcaggcgacg aatagaggac acagttttcc atggtggtag
    44821 aagacatttc cccaactgtc ataaagctat cgtcagatcc aaaagtggct tggttcatca
    44881 tacgcaaata gttatgaacg atgggtttgt ctgtataagc tggcttccct tcattttcag
    44941 gacagtccac tgaaacctcg tccttaccaa tcaaattgat cacatcaaat cgaaaacctt
    45001 tgacaccctt gtcgcgccag aaattaacaa ccttgaaaag ctccttacgg acattgggat
    45061 tgcgccagtt aaggtcagcc tgggtctcat caaataggtg aagatagtat ttcccagtat
    45121 ccccgaaagg cgcccatgca gaaccaccaa acttagactg ccaatctgtt ggttggtctt
    45181 ggatgaagaa aaagtcttga taatacttat caccagctag ggctttctga aaccattcat
    45241 gctctgtcga acaatgatta agtaccatgt ccagcataaa gtcaatcttg tgctctttac
    45301 cgatacacac catttcctca aaatcagcca tatcaccaaa aagaggatcc actgccatat
    45361 aatctgaaat atcgtaacca ttatcccgtt gaggacttgg atagaatgga ttgagccaga
    45421 ccatatccac acctagtttg gctagatagg gaatttttcc gataatccca cggaaatccc
    45481 caataccatt gccagtggtg tctttgtaag attttggata gatttgatag actacttttc
    45541 ctttatcaag tgtcatctgt ttctcctttt ctgataaaag ggaggaagca gtcttccgtc
    45601 cctatttgtg ctatttcaat tatactcaat gaaaatcaaa gagcaaacta ggaagctagc
    45661 cacaggttgc tcaaaacact gttttgaggt tgcagataga gctgacgtgg tttgaagaga
    45721 ttttcgaaga gtattagatt cgtgtagcga ccatgagaga tgctccagct tgaatcgttg
    45781 tcggataagt tccgggaata gtcgctgtat aagcatcttg gttggtgatg ataacaggag
    45841 tttctgtcac cagacctgca gccttaatga catccatatc aaaacgaatc agttgctgac
    45901 caactgtaac gtgatctcct tggactacaa gactttcaaa acctttgcca tcaagaccta
    45961 ctgtatccat accgatgtgg atgagcaatt caactccctc gtcagagaca atgccgatgg
    46021 catgcttggt agggaaaaga accgtcactg tcccattaac tggagaggtc aactcacctt
    46081 ggcttggttc aatgactaga ccttgcccca tgacacctga tgcaaaaata ggatccgtcg
    46141 cttgactcaa ttctttcact tggccagtta gtgggctgat aatttctacc gaagtaagtt
    46201 ctactggttc atggttcaca aattctgctt cttcttgagc aacgaattct gcctgcaagt
    46261 tcgtatcgcc ctctgttttt gtaaagagac cagccttgcg gaagaagaaa gtcaagagca
    46321 ttggaacaac aatcgcaact agcatagttc ctgcaaatgg cagcatgtat tgaggttgaa
    46381 tagagagaat acctggcaaa ccaccgatac caatagaagc cgcagttaca ttaaaagtaa
    46441 cggataacat gcctgcaagg gctgaaccag tcatcccagc aacaaatgga taaatatatt
    46501 ttacgttaac cccaaaaaga gctggttctg taacaccgag ataggctgaa atggttgcag
    46561 gaagtgaaac ctgagcctca cgctcatcat ggcgatgcat gaaataatag gcaaacacgg
    46621 ctgagccttg agcaatatta gaaagagcaa tcattggcca tagggcagtg ccaccagcat
    46681 ccgcaatcaa ttgtgtatca atggcattgg tcatatggtg cagacctgtg atgacaaatg
    46741 gagcgtagag ggcaccaaaa attgcaccga agagccattt aactggacca gttaaacctg
    46801 ccaagacaac tgatgaaagt ccttgtccaa ttgtccaacc gattggtccc aaaacagtat
    46861 gagccaaaat caaggctgga atcaatgaca agaaaggtac aaaaatcata gaaatgactt
    46921 ctgggatatg cttgcgccag aagatttcaa gataagatag actcaaacct gcaagcaagg
    46981 ctgggataac ttgggcttgg taaccgatac gattaacagt aaaatagcca aaattccaaa
    47041 cccagtttgc cgcgatatca gctgctggcg ttgaagcaac cgcataggca ttgagcaact
    47101 gaggcgatac caaacagatt ccgagaacaa ttcccaaaat ttggctggtt cccatcttac
    47161 gagaaacaga ccaagtaatc cctactggta agaactggaa gatagcttca ccaggcaacc
    47221 agaggaaatg attaacacct gcccaaaact gagaggattc tgtgatggtc ttgccatcca
    47281 acatcgacca atggacacct tccaagacat tacggaaacc gaggatcaat cctccgacta
    47341 tcaaggctgg aataatcgga gtaaaaatct ccgccagagt ggtcatgaca cgttggacca
    47401 cgttttgatt actcttagct gcagacttgg ctgcttcttt ggaaacaccc tcaatacctg
    47461 aaacagctgt aaaatcatta taaaagatgg gcacgtcatt tccaatgatt acctgaaatt
    47521 gacctgcatt tgtaaaggtt cctttaacag ctggaattga ctcgatagct ttaacattag
    47581 ccttcttatc atttcctaaa acaaagcgca tccgtgttgc acagtgagtt acggcagtca
    47641 cattttcttt gcctccgatt gcctgaagca gatctttggc ttcttgttca aattttccca
    47701 tttgattctc cttatacttg tcaaagcaag tttgatttga taagtatatt gtaaacgata
    47761 ccaaacttgt ctgcaacttg tttggtataa aaagggtgtt tttttgtaaa ttttctagca
    47821 cttgtatggt aaaatagata caggtgttca ttaaactaga ctaaaaacct atttaagcag
    47881 gcaaaatgaa gaaataccaa caattattta agcaaatcca agaaaccatt caaaacgaga
    47941 cttacgctgt cggagatttc cttcctagcg agcacgacct tatggagcaa tatcaagtga
    48001 gtcgtgatac cgtccgaaag gccctgtctc tcctccaaga ggaaggattg atcaaaaaga
    48061 taagagggca aggttctcaa gtcgtcaaag aagaaaccgt caatttccct gtatccaacc
    48121 taaccagcta ccaagaacta gttaaagaac ttggactgcg ctctaaaacc aacgtggtca
    48181 gtctggacaa gattattatt gataaaaaat cctcactgat aaccggtttc ccagagtttc
    48241 ggatggtttg gaaggtggtc cgccagcgtg tggtggatga tctggtatcc gttctggata
    48301 cggactatct ggatatggaa ctcatcccaa atctcactcg ccaaattgct gagcagtcta
    48361 tctattctta tatagaaaat ggcctcaaac tccttattga ttatgctcag aaggaaatca
    48421 ccattgacca ctcaagcgac cgagacaaga ttctcatgga cattggcaaa gacccttatg
    48481 tcgtttcgat taaatcaaaa gtctatctcc aagacgggcg ccaatttcag tttaccgaaa
    48541 gtcgccataa gttagaaaaa tttagatttg tagattttgc aaaacgcaag aaataaaaga
    48601 ctgagacacc agatctcagc ctttttcttt atcccaaaac taattcatca ctgaccagac
    48661 tttggccact atttttctgg aagagatgca taaggtcttc aactgtcaga tgctttttct
    48721 cttctccctt gacatccacc actatcttgc cttgatagag cataatgaga cgattgccgt
    48781 actcaatcgc atgattcata tcatgggtaa tcatcaaagt cgtccactga tggtactcca
    48841 caatcttttg cgtcaagtcc atcaccattt gactggtttt cgggtcaagt gccgcagtat
    48901 gttcatccaa aagcaaaagt ttgagtttca ccagagctgc catgactagg gtcaaagcct
    48961 gtctttgtcc tcctgagaga tattgagtat ctacttttaa gcggttttca agaccaatat
    49021 tcaactcctt caaggcctct tggaactgga ttctatcctt ctccttcacg ccccaaccaa
    49081 gccctctctt ttgcccacgt ctcaaggcaa tagccatatt ctcctcaatc gtcaaacgag
    49141 aagctgttcc catcttagga tcttgaaaaa cacgggcaat atccttggct ctctttctga
    49201 cactcagatg tttaatggat ttccctgcca gtagaaggtc cccttcgtcc accgatagat
    49261 taccagccaa gatattcatc aaagtggatt ttcctgctcc atttccacca atcacagaga
    49321 taaaatctcc ctcttcaacc tctaaatcta atcctttgag gacatggttc tcattgaccg
    49381 tccctgcttc aaatgtcttg tgaatatttt caagtgttaa caaacttgcc ataactttct
    49441 cctcctattc atttctcaat ttcagaccac gaatctttaa tctcttttgc aatgctggtg
    49501 caaataaaac caaagcgagc aagattgcat taaagagacg taccaagttt tgatctagat
    49561 ttggaatttc atagatattt aaaataatca aacggtaaac aatagcaccg attccgatgg
    49621 ataataagcg gcctccaatg gtcaagtcgt gtatcaagac ttccgagctc aaaccaacaa
    49681 caatggttcc tgtcccagaa gtcacatctg aaaatccatc attttgggca aacaaggaac
    49741 cacatagggc aatcaaaccg gttgaaatca tgtaaccaac aatcttcatg gtgtttacat
    49801 tgactccatt ggcctcactc atcgggatat tgtccccagt cgaacgcaag accaaaccaa
    49861 tctctgtttt catcaaaagg gtcaaaacca aacaagtaag agacagacta aactaagtga
    49921 gaaaacagct ccttcatttg tcagacccaa gctcgccaac tgtttaaaga cggttgcaga
    49981 atctcccaag gaaagattgg gtacactgcc catgatttta atattgattg aatagagccc
    50041 tgtcaaggtc acaatccctg tcaagagagc tgggattttc atcttggtgt ggagcattcc
    50101 tgatataaga cctgctacca tacctgccag caaagcaagt aaagtcgcaa gccaaggatt
    50161 tgcccctgcc tgtatctgtg atacaacgat tgctgccccc ataggaaagg ctccctcagc
    50221 agtcatatcc gcaatatcca aaatacggaa agtcaagtag accccaattg ccataatcga
    50281 ccacaacaaa ccttctgata aactagataa cacaaaattc atcttaatcc tccttattcc
    50341 ttgccttcta acttactaat atcaattcac aatgcatctg ccatttcttg attagtatgc
    50401 aattccagtt tttcaggcaa ctcaactgct atattttctg gttcctcacc ttttaaaaca
    50461 cgaatcagca tgcgagctgt ctgtcttccc aattcttcat aattggttcc gtagttatac
    50521 aagccaccaa cagcaatcat ttctgttgaa ccaccgaata ctggaacctt gtgtttaata
    50581 gaaacctgct taactgtttc catggttgac gaaatgatat tatcagttgg gacaaaaacc
    50641 atatccacct ctgccatcaa actctctgct gccgccttga cgttattact gtccaagatt
    50701 gttttttcaa caacggtaaa gcctttttct ttcagaaatc gcttagcttc atccttttaa
    50761 acaaccgaat tgggctcgct ctgagtatag aggattccaa tcgttttagc ctttagcaac
    50821 actttcttta tcaaattgat ttgggttgaa atggcatctg atgactgatc gcttgtccca
    50881 gttacattgc ccccaggatg ttctcttgac tcaaccaact tggcactgac tgggtctgtt
    50941 acagctgaaa agataactgg tgtcgtttgc gtcgtattgg ccaagctctg agcagaaggc
    51001 cttgcgatgg ctagaacgac atcgctggat tctgctagtt gctgggaaat cgtttttaga
    51061 tttctttgtt ctccctgtgc attttgcaaa tcaatctcaa tattttcccc ctcaacatag
    51121 ccttgtttgg ccagctcatc cacaaatcct tctctagtag cgtctaagga ctggtgggta
    51181 ataaactgcg aaataccgat acgaaagaca tctcttttct tatctgcctt caactgatgc
    51241 aaactgatca gagaagtcaa gaggatcccc actaccaaga gggggctagt gattttcgaa
    51301 caactttcat aatgaaactc cttctcagaa aagataaaac aaaaaaacgc ctagatacta
    51361 tctaaacggg tacttgaaat aacctaacaa gttacaactt agctggtcca tttagatatt
    51421 catctatatg gaccacaatc aaaaatctta gccacataga tacaaacaaa ttgcttgaac
    51481 tgtttgcatc catggtgaca tgtctacaaa cactatctaa agtagctaaa gtaaaagttt
    51541 tgattcatag ttacggcttg tctcttattc atttcttttt ctgctttctt ttttgatcct
    51601 tcctatccta ccaccttttt catcacctgt caataatatt tcaaaatttt ttaaaatttt
    51661 tcgaaaattc tttcag
//
LOCUS       DAVBEO010000007        48474 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 009
            SAMEA1678075-rid20185393.denovo.007, whole genome shotgun sequence.
ACCESSION   DAVBEO010000007 DAVBEO010000000
VERSION     DAVBEO010000007.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678075
            Sequence Read Archive: ERR226392
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 48474)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 48474)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980207.1
            Genome Coverage       :: 150x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:50:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 72 of 147
            Pseudo Genes (incomplete)         :: 72 of 147
            Pseudo Genes (internal stop)      :: 42 of 147
            Pseudo Genes (multiple problems)  :: 32 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..48474
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678075-rid20185393.denovo.007"
                     /strain="KS 009"
                     /db_xref="taxon:1313"
     gene            complement(308..1474)
                     /gene="recA"
                     /locus_tag="VQ543_000463"
     CDS             complement(308..1474)
                     /gene="recA"
                     /locus_tag="VQ543_000463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecA"
                     /protein_id="HET2611245.1"
                     /translation="MAKKPKKLEEISKKFGAEREKALNDALKLIEKDFGKGSIMRLGE
                     RAEQKVQVMSSGSLALDIALGSGGYPKGRIIEIYGPESSGKTTVALHAVAQAQKEGGI
                     AAFIDAEHALDPAYAAALGVNIDELLLSQPDSGEQGLEIAGKLIDSGAVDLVVVDSVA
                     ALVPRAEIDGDIGDSHVGLQARMMSQAMRKLGASINKTKTIAIFINQLREKVGVMFGN
                     PETTPGGRALKFYASVRLDVRGNTQIKGTGDQKETNVGKETKIKVVKNKVAPPFKEAV
                     VEIMYGEGISKTGELLKIASDLDIIKKAGAWYSYKDEKIGQGSENAKKYLAEHPEIFD
                     EIDKQVRSKFGLIDGEEVSEQDTENKKDEPKKEEAVNEEVPLDLGDELEIEIEE"
     gene            complement(1529..2785)
                     /locus_tag="VQ543_000464"
     CDS             complement(1529..2785)
                     /locus_tag="VQ543_000464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000642700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence/damage-inducible protein A"
                     /protein_id="HET2611246.1"
                     /translation="MKAEIIAVGTEILTGQIVNTNAQFLSEKLAEIGVDVYFQTAVGD
                     NEVRLLSLLEIASQRSSLVILTGGLGPTEDDLTKQTLAKFLGKALVFDPQAQEKLDIF
                     FALRPDYARTPNNERQAQIVEGAIPLPNETGLAVGGKLEVDGVTYVVLPGPPSELKPM
                     VLNLLLPKLMTGSKLYSRVLRFFGIGESQLVTILADLIDNQVDPTLAPYAKTGEVTLR
                     LSTKASSQEEANQALDILENQILDCQTFEGISLRDFCYGYGEETSLASIVVEELKRQG
                     KTIAAAESLTAGLFQATVANFSGISSIFKGGFVTYSLEEKSRMLDIPAKNLEEHGVVS
                     EFTAQKMAEQARSKTQSDFGISLTGVAGPDSLEGHPVGTVFIGLAQDQGTEVIKVNIG
                     GRSRADVRHIAVMHAFNLVRKALLSD"
     gene            complement(2869..3885)
                     /locus_tag="VQ543_000465"
     CDS             complement(2869..3885)
                     /locus_tag="VQ543_000465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000239264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HET2611247.1"
                     /translation="MVKKIIGMVLALLSVTVVGVGVFAYTIYQQGTETLAKTYKKIGE
                     ETKVIEATEPLTILLMGVDTGNVERTETWVGRSDSMILMTVNPKTKKTTMMSLERDIL
                     TRIESGNGQAHEAKLNSAYADGGAELAIETIQKMMNIHIDRYVMVNMRGLQKLVDAVG
                     GITVNNILGFPISISDQEEFNTISIGVGEQHIGGEKALVYARMRYQDPEGDYGRQKRQ
                     REVIQKVMEKALSLNSVGHYQEILKALSDNMQTNIDLSAKSIPNLLGYKDSFKTIETQ
                     QLQGEGEILQGVSYQIVSRAHMLEMQNILRRSLGQEEVTQLETNAVLFEDLFGRAPVG
                     DEDN"
     gene            complement(3893..4411)
                     /locus_tag="VQ543_000466"
     CDS             complement(3893..4411)
                     /locus_tag="VQ543_000466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET2611248.1"
                     /translation="MEYELLIREAEPKDAAELVAFLNRVSLETDFTSLDGDGILLTSE
                     EMEIFLNKQASSDNQITLLAFLNGKIAGIVNITADQRKRVRHIGDLFIVIGKRYWNNG
                     LGSLLLEEAIEWAQASGILRRLQLTVQTRNQAAVHLYQKHGFVIEGSQERGAYIEEGK
                     FIDVYLMGKLIG"
     gene            complement(4401..4844)
                     /gene="tsaE"
                     /locus_tag="VQ543_000467"
     CDS             complement(4401..4844)
                     /gene="tsaE"
                     /locus_tag="VQ543_000467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000288243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     ATPase subunit type 1 TsaE"
                     /protein_id="HET2611249.1"
                     /translation="MYTKNEEELQALGERLGHLLAKNDVLILTGELGAGKTTFTKGLA
                     KGLQISQMIKSPTYTIVREYEGRLPLYHLDVYRIEGDADSIDLDEFIFGGGVTVIEWG
                     NLLGDALPDAYLELEILKEADGRRLNFQAKGLRAEKLLEELQYGV"
     gene            complement(4930..5550)
                     /locus_tag="VQ543_000468"
     CDS             complement(4930..5550)
                     /locus_tag="VQ543_000468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000839915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2611250.1"
                     /translation="MKSMRILFLLALIQISLSSCFLWKECILSFKQSTAFFIGSMVFV
                     SGICAGVNYLYTRKQEVHSVLASKKSVKLFYSMLLLINLLGAVLVLSDNLFIKNTLQQ
                     ELVDFLLPSFFFLFGLDLLIFLPLKKYVRDFLAMLDRKKTVLVTILATLLFLRNPMTI
                     VSLLIYIGLGLFFAAYLVPNSVKKEVSFYGHIFRDLVLVIVTLIFF"
     gene            complement(5933..6796)
                     /locus_tag="VQ543_000469"
                     /pseudo
     CDS             complement(5933..6796)
                     /locus_tag="VQ543_000469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093609.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            6961..7155
                     /locus_tag="VQ543_000470"
     CDS             6961..7155
                     /locus_tag="VQ543_000470"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2611251.1"
                     /translation="MKKKRVSRMKKNRGIQKLAILVLLGVFMFSNTIPYQQFIQKNRQ
                     LEIRVQSQKKSNGLDVGKAD"
     gene            7470..7766
                     /locus_tag="VQ543_000471"
     CDS             7470..7766
                     /locus_tag="VQ543_000471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000911560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
                     /protein_id="HET2611252.1"
                     /translation="MLKFRKVVASSLAVLAFSLALPVLAVSHRGGEWTYGGHHDPNNW
                     GAFSNYYHGSQYHWAYVGSNGRNNQKTVYAGARSAAYAFVNTNFGEQVTFDAGW"
     gene            7869..9884
                     /locus_tag="VQ543_000472"
     CDS             7869..9884
                     /locus_tag="VQ543_000472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HET2611253.1"
                     /translation="MKKLFILISNLLASLFFVWVFTIWTDTYVSYYYPNVVVHDSSPE
                     TTFQHVATRLEKLAEETDSFIAIQHQDPNSEGTTVFSYTTFGDGKLPDGLQEKKLEDA
                     QSSSVETNYFVFDGHLDIHLLREELSQLGLTNMNLTIPSKLSTLMAIFSNGFQLISLL
                     IFILTFIALTLISQISQLRSSGIRLISGEKRWSIFLRPVGEDLKGIAVGFSLAGVLAI
                     LMQKILSLPTQSLMTIGAGLLSYNLILLSISLFFAQLFAVGIKKIHLMQIIKGQVPVR
                     GIISLILIGQLLAIIIVTLGIGSSLKYSQAWQQHRIGQEAWSQERQLITLSISREGTS
                     PGFDEQAQRKLRTWYQLMDLAVSEQKAFLSRHQLIDRTLQNGMASSKNLITSTEWHDY
                     NPNGNVLIVTPQYLERQNIPVDTTIEQKMNHLDVGEFVLLLPEHLRSEEEHYKSVFED
                     DLTSRMSSQDERQQMTATVGYLESGQDRFVYNTTPISYQQFLKDPIIIVITPQSTGPQ
                     SILFWIDAVQNYVLFNQLSDAQELIQRQGIENWVSEMQTGYHNYITLLDNIQRERWVM
                     LAGAGLGIATSILLFNTMNRLYFEEFRRAIFIKRIAGLRFLEIHRTYLFAQLGVFLLG
                     FVASVFLQVEIGVAFLVLLLFTGLSLLQLHVQMQKENKMSMLVLKGG"
     gene            9886..10518
                     /locus_tag="VQ543_000473"
     CDS             9886..10518
                     /locus_tag="VQ543_000473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2611254.1"
                     /translation="MIELKQVSKSFGERELFSNLSMTFEAGKVYALIGSSGSGKTTLM
                     NMIGKLEPYDGTIFYRGKDLANYKSSDFFRHELGYLFQNFGLIENQSIEENLKLGLIG
                     QKLSRSEQRLRQKQALEQVGLTYLDLDKRIFELSGGESQRVALAKVILKNPPFILADE
                     PTASIDPATSQLIMEILLSLRDDNRLIIIATHNPAIWEMADEVFTMDRLK"
     gene            10659..10937
                     /locus_tag="VQ543_000474"
     CDS             10659..10937
                     /locus_tag="VQ543_000474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001843943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComA"
                     /protein_id="HET2611255.1"
                     /translation="MKKFDNYIVEKPCDSNSDKLQKILIIENLVDDILQFPLRINNSV
                     GEIFLLQPFQKKTIFIPCYFEEDIVKVKDDDKVEWNLLEFQKFRAFLA"
     gene            complement(11446..11859)
                     /gene="ndk"
                     /locus_tag="VQ543_000475"
     CDS             complement(11446..11859)
                     /gene="ndk"
                     /locus_tag="VQ543_000475"
                     /EC_number="2.7.4.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000438285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-diphosphate kinase"
                     /protein_id="HET2611256.1"
                     /translation="MEQTFFIIKPDGVKRGLVGEVLKRIEQRGFTIEKLEFRSQVSEE
                     LIDQHYQDLVGQSFYPPIREFMTSGPVLVGVISGPKVIETWRTMMGATRPEEALPGTI
                     RGDFAKAAGENEVIQNVVHGSDSEESAKREIALWF"
     gene            complement(11970..15647)
                     /gene="rpoC"
                     /locus_tag="VQ543_000476"
     CDS             complement(11970..15647)
                     /gene="rpoC"
                     /locus_tag="VQ543_000476"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000228741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta'"
                     /protein_id="HET2611257.1"
                     /translation="MVDVNRFKSMQITLASPSKVRSWSYGEVKKPETINYRTLKPERE
                     GLFDEVIFGPTKDWECACGKYKRIRYRGIVCDRCGVEVTRTKVRRERMGHIELKAPVS
                     HIWYFKGIPSRMGLTLDMSPRALEEVIYFAAYVVIDPKDTPLEHKSIMTEREYRERLR
                     EYGYGSFVAKMGAEAIQDLLKQVDLEKEIAELKEELKTATGQKRVKAIRRLDVLDAFY
                     KSGNKPEWMILNILPVIPPDLRPMLQLDGGRFASSDLNDLYRRVINRNNRLARLLELN
                     APGIIVQNEKRMLQEAVDALIDNGRRGRPITGPGSRPLKSLSHMLKGKQGRFRQNLLG
                     KRVDFSGRSVIAVGPTLKMYQCGVPREMAIELFKPFVMREIVARDIVQNVKAAKRLVE
                     RGDERIWDILEEVIKEHPVLLNRAPTLHRLGIQAFEPVLIDGKALRLHPLVCEAYNAD
                     FDGDQMAIHVPLSEEAQAEARILMLAAEHILNPKDGKPVVTPSQDMVLGNYYLTMEEA
                     GREGEGMVFKDRDEAVMAYRNGYVHLHSRVGIATDSLNKPWTEEQRHKVLLTTVGKIL
                     FNDIMPEGLPYLQEPNNANLTEGVPAKYFLPLGGDIKEAISNLELNPPFKKKNLGNII
                     AEIFKRFRTTETSALLDRMKNLGYHHSTLAGLTVGIADIPVVDDKAEIIEESHKRVEQ
                     ITKQFRRGMITDDERYNAVTAEWRAAREKLEKRLIANQDPKNPIVMMMDSGARGNISN
                     FSQLAGMRGLMAAPNGRIMELPILSNFREGLSVLEMFFSTHGARKGMTDTALKTADSG
                     YLTRRLVDVAQDVIIREDDCGTDRGLLIRSIAEGKEMIESLEERLNGRYTKKTVKHPE
                     TGAVIIGPNELITEDKAREIVNAGVEEVTIRSVFTCNTRHGVCRHCYGINLATGDAVE
                     VGEAVGTIAAQSIGEPGTQLTMRTFHTGGVASNTDITQGLPRVQEIFEARNPKGEAVI
                     TEVKGEVTAIEEDASTRTKKVFVKGETGEGEYVVPFTARMRVEVGGQVARGAALTEGS
                     IQPKRLLAVRDVLSVETYLLGEVQKVYRSQGVEIGDKHIEVMVRQMIRKVRVMDPGDT
                     DLLMGTLMDINDFTDANKDVLIAGGVPATGRPVLMGITKASLETNSFLSAASFQETTR
                     VLTDAAIRGKKDHLLGLKENVIIGKIIPAGTGMARYRNLEPYAVNEEEYLNPPVEEEG
                     NEETTEVVVDTAVETVEETVE"
     gene            complement(15680..19291)
                     /gene="rpoB"
                     /locus_tag="VQ543_000477"
     CDS             complement(15680..19291)
                     /gene="rpoB"
                     /locus_tag="VQ543_000477"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000907130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HET2611258.1"
                     /translation="MAGHDVQYGKHRTRRSFSRIKEVLDLPNLIEIQTDSFKAFLDHG
                     LKEVFEDVLPISNFTDTMELEFVGYEIKEPKYTLEEARIHDASYSAPIFVTFRLINKE
                     TGEIKTQEVFFGDFPIMTEMGTFIINGGERIIVSQLVRSPGVYFNDKVDKNGKVGYGS
                     TVIPNRGAWLELESDSKDITYTRIDRTRKIPFTTLVRALGFSGDDEIFDIFGDSELVR
                     NTVEKDIHKNPMDSRTDEALKEIYERLRPGEPKTAESSRSLLVARFFDPRRYDLAAVG
                     RYKINKKLNVKTRLLNQTIAEPLVDPETGEILVEAGTIMTRSVIESIESHLDGDLNKI
                     VYIPNDAAVVTEPVVLQKFKVVAPTDPDRVVTIIGNANPDDKVRTVTPADILAEMSYF
                     LNLAEGLGRVDDIDHLGNRRIRAVGELLANQVRLGLSRMERNVRERMSVQDNEVLTPQ
                     QIINIRPVTAAVKEFFGSSQLSQFMDQHNPLSELSHKRRLSALGPGGLTRDRAGYEVR
                     DVHYTHYGRMCPIETPEGPNIGLINNLSSYGHLNKYGFVQTPYRKVDRETGVVTNEIV
                     WLTADEEDEYTVAQANSSLNEDGTFAEKIVMGRHQGVNQEYPANIVDYMDVSPKQVVA
                     VATACIPFLENDDSNRALMGANMQRQAVPLINPQAPYVGTGMEYQAAHDSGAAVIAQY
                     DGKVTYADADKVEVRREDGSLDVYHIQKFRRSNSGTAYNQRTLVKVGDVVEKGDFIAD
                     GPSMENGEMALGQNPIVAYMTWEGYNFEDAVIMSERLVKDDVYTSVHLEEYESETRDT
                     KLGPEEITREIPNVGEDALKDLDEMGIIRIGAEVKEGDILVGKVTPKGEKDLSAEERL
                     LHAIFGDKSREVRDTSLRVPHGADGVVRDVKIFTRVNGDELQSGVNMLVRVYIAQKRK
                     IKVGDKMAGRHGNKGVVSRIVPVEDMPYLPDGTPVDIMLNPLGVPSRMNIGQVMELHL
                     GMAARTLGIHIATPVFDGASSEDLWSTVKEAGMDSDAKTILYDGRTGEPFDNRVSVGV
                     MYMIKLHHMVDDKLHARSVGPYSTVTQQPLGGKAQFGGQRFGEMEVWALEAYGASNVL
                     QEILTYKSDDINGRLKAYEAITKGKPIPKPGVPESFRVLVKELQSLGLDMRVLDEDDQ
                     EVELRDLDEGMDEDVIHVDDLEKAREKAAQEAKAAFEAEEAEKATKAEATEEAAEQE"
     gene            19707..19777
                     /locus_tag="VQ543_000478"
     tRNA            19707..19777
                     /locus_tag="VQ543_000478"
                     /product="tRNA-Cys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:19739..19741,aa:Cys,seq:gca)
     gene            complement(19975..21306)
                     /locus_tag="VQ543_000479"
     CDS             complement(19975..21306)
                     /locus_tag="VQ543_000479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000390004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HET2611259.1"
                     /translation="MEDPSSQNLLLQFVLLFILTVLNAFFSATEMAMVSLNRARVEQK
                     AEEGDRRYIRLLKVLENPNHFLSTIQVGITLITILSGASLTDTLGRVIASWLGNGETA
                     QAVATFLSLAFLTYISIVFGELYPKRIALNLKDALAIRTAPVIIGIGKLVSPFVWLLA
                     ASTNFLSHLTPMSFDDADEKMTRDEIAYMLTNSEETLDADEIEMLQGVFSLDELMARE
                     VMVPRTDAFMVDIQDDSQAIIQSILKQNYSRIPVYDGDKDNVIGIIHTKSLLKAGFVD
                     GFDNIVWKRILQDPLFVPETIFVDDLLKELRNTQRQMAILLDEYGGMAGLVTLEDLLE
                     EIVGEIDDETDKAAIDVHQIGEDTYIVQGTMTLNDFNNYFNVELESDDVDTIAGYYLT
                     GVGTIPTTEKLSYELVSQNKQFILTNDKVKNGRVTKVKVQITEVEIEEETE"
     gene            complement(21597..22421)
                     /gene="endA"
                     /locus_tag="VQ543_000480"
     CDS             complement(21597..22421)
                     /gene="endA"
                     /locus_tag="VQ543_000480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-entry nuclease EndA"
                     /protein_id="HET2611260.1"
                     /translation="MNKKTRQTLIGLLVLLLLSTGSYYIKQMQSTANSPKTKLSQKKQ
                     APEAPSQALAESVLTDAVKSQIKGSLEWNGSGAFIVNGNKTNLDAKVSSKPYADNKTK
                     TVGKETVPTVANALLSKATRQYKNRKETGNGSTSWTPPGWHQVKNLKGSYTHAVDRGH
                     LLGYALIGGLDGFDASTSNPKNIAVQTAWANQAQAEYSTGQNYYESKVRKALDQNKRV
                     RYRVTLYYASNEDLVPSASQIEAKSSDGELEFNVLVPNVQKGLQLDYRTGEVTVTQ"
     gene            complement(22460..22648)
                     /locus_tag="VQ543_000481"
     CDS             complement(22460..22648)
                     /locus_tag="VQ543_000481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HET2611261.1"
                     /translation="MNKKSSYVVKRLLLVIIVLILGTLALGIGLMVGYGILGKGQDSW
                     AILSPAKWQELIHKFTGN"
     gene            complement(22641..23924)
                     /gene="murA"
                     /locus_tag="VQ543_000482"
     CDS             complement(22641..23924)
                     /gene="murA"
                     /locus_tag="VQ543_000482"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HET2611262.1"
                     /translation="MDKIVVQGGDNRLVGSVTIEGAKNAVLPLLAATILASEGKTVLQ
                     NVPILSDVFIMNQVVGGLNAKVDFDEEAHLVKVDATGDITEEAPYKYVSKMRASIVVL
                     GPILARVGHAKVSMPGGCTIGSRPIDLHLKGLEAMGVKISQTAGYIEAKAERLHGAHI
                     YMDFPSVGATQNLMMAATLADGVTVIENAAREPEIVDLAILLNEMGAKVKGAGTETIT
                     ITGVEKLHGTTHNVVQDRIEAGTFMVAAAMTGGDVLIRDAVWEHNRPLIAKLLEMGVE
                     VIEEDEGIRVRSQLENLKAVHVKTLPHPGFPTDMQAQFTALMTVAKGESTMVETVFEN
                     RFQHLEEMRRMGLHSEIIRDTARIVGGQPLQGAEVLSTDLRASAALILTGLVAQGETV
                     VGKLVHLDRGYYGFHEKLAQLGAKIQRIEASDEDE"
     gene            complement(23948..24178)
                     /locus_tag="VQ543_000483"
     CDS             complement(23948..24178)
                     /locus_tag="VQ543_000483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014017351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1146 domain-containing protein"
                     /protein_id="HET2611263.1"
                     /translation="MVQLLFTLSSHMLFIYVSFYLLKDLVRWEKVLKVTAENTRKVRV
                     LVAFFSIVIGYILSSFFISLYHLWQEALRGLL"
     gene            complement(24236..25273)
                     /locus_tag="VQ543_000484"
     CDS             complement(24236..25273)
                     /locus_tag="VQ543_000484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PDZ domain-containing protein"
                     /protein_id="HET2611264.1"
                     /translation="MKKKIRWPLYVIAALIVTFLAFVVPLPYYIEVPGGSEDIRQVLK
                     VNDTEDKEAGAYQFVTVGVQHATLAHMIYAWLTPFTDIRSAQETTGGSSDVEFMRINQ
                     FYMQTSQNMAKYQGLKTAGKDIELKYFGVYVLNVTDNSTFKGILNISDTVTAVNDQTF
                     DSSKDLIDYVSSQKLGDSVKVTYEEDGQTKSAEGKIITLENGKNGIGIGLIDRTEVIS
                     NVPISFSTAGIGGPSAGLMFSLAIYTQIAHPDLRNGRIVAGTGTIDRDGNVGDIGGID
                     KKVVASARAGAAIFFAPDNPVSEEEQKAHPDAKNNYQTALEAAKTIKTDMKIVPVKTL
                     QDAIDYLKNNP"
     gene            complement(25257..25745)
                     /gene="coaD"
                     /locus_tag="VQ543_000485"
     CDS             complement(25257..25745)
                     /gene="coaD"
                     /locus_tag="VQ543_000485"
                     /EC_number="2.7.7.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pantetheine-phosphate adenylyltransferase"
                     /protein_id="HET2611265.1"
                     /translation="MSDKIGLFTGSFDPMTNGHLDIIERASRLFDKLCVGIFFNPHKQ
                     GFLPLENRKRGLEKALGHLENVEVVASHDELVVDVAKRLGATCLVRGLRNASDLQYEA
                     SFDYYNHQLSSDIETIYLHSRPEHLYISSSGVRELLKFGQDIACYVPESILEEIRNEK
                     KD"
     gene            complement(25735..26274)
                     /gene="rsmD"
                     /locus_tag="VQ543_000486"
     CDS             complement(25735..26274)
                     /gene="rsmD"
                     /locus_tag="VQ543_000486"
                     /EC_number="2.1.1.171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006147838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(966)-N(2))-methyltransferase
                     RsmD"
                     /protein_id="HET2611266.1"
                     /translation="MKIVSGIYGGRPLKTLEGKTTRPTSDKVRGAIFNMIGPYFEVGR
                     VLDLYAGSGGLSIEAVSRGMSSAVLVERDRKAQTIVAENIQMTKEVGKFQLLKMDAER
                     ALEQVSGEFDLVFLDPPYAKEQIVADIEKMAERELFSEDVMVVCETDKTVELPEEIAC
                     LGIWKEKIYGISKVTVYVR"
     gene            complement(26339..27331)
                     /locus_tag="VQ543_000487"
     CDS             complement(26339..27331)
                     /locus_tag="VQ543_000487"
                     /EC_number="6.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016502595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--ammonia ligase"
                     /protein_id="HET2611267.1"
                     /translation="MKKSFIHQQEEISFVKNTFTQYLKDKLEVVEVQGPILSKVGDGM
                     QDNLSGVENPVSVKVLQIPDATYEVVHSLAKWKRHTLARFGFGEGEGLFVHMKALRPD
                     EDSLDATHSVYVDQWDWEKVIPNGKRNIVYLKETVEKIYKAIRLTELAVEARYDIESI
                     LPKQITFIHTEELVERYPDLTPKERENAICKEFGAVFLIGIGGELPDGKPHDGRAPDY
                     DDWTSESENGYKGLNGDILVWNESLGGAFELSSMGIRVDEETLRRQVEITGDEDRLEL
                     EWHKSLLNGLFPLTIGGGIGQSRMAMFLLRKRHIGEVQTSVWPQEVRDTYENIL"
     gene            complement(27443..28126)
                     /locus_tag="VQ543_000488"
     CDS             complement(27443..28126)
                     /locus_tag="VQ543_000488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015545711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Bax inhibitor-1/YccA family protein"
                     /protein_id="HET2611268.1"
                     /translation="MNHTIIHDRAGLNQFYAKVYAFVGLGIGLSALVSGLMLTVFQSQ
                     LVYLLMQGRLWLTIATFAELALVFVASSMASRNSPAALPVFLLYSVLNGFTLSFVVAF
                     YTPGTVLSAFVSSALLFFVMAAVGIFTKKDLSGIGRAMMAALIGLLIAMVVNIFLASG
                     FFDYMISVAMVLVFSGLIAWDNQKIRLAYEQSQGRVATGWVVSMALSIYLDFINLFLS
                     ILRIFGRND"
     gene            complement(28182..28922)
                     /locus_tag="VQ543_000489"
     CDS             complement(28182..28922)
                     /locus_tag="VQ543_000489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000152696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA methyltransferase"
                     /protein_id="HET2611269.1"
                     /translation="MTIITSKANSVVKNAKKLHQKKYRKSAYLIEGWHLFEEAVQAGV
                     TIEKIFALENYRNQLAAFPQTVWISEDILLDLADSQTPQGIVAVVQKEEVGQADLSQG
                     KFLFLEDVQDPGNVGTIIRTADAAGFTGVIVSDKSADIYSLKTLRSMQGSHFHLPIYR
                     MTSQALLDETKKVAIPVLATTLSKDSVDYRELPSIENFVLVMGNEGQGISPLMAESAD
                     QLVHISMKGQAESLNVAVAAGILIFHLS"
     gene            28956..29234
                     /locus_tag="VQ543_000490"
     CDS             28956..29234
                     /locus_tag="VQ543_000490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001174612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylphosphatase"
                     /protein_id="HET2611270.1"
                     /translation="MQKVRMIAQGRVQGVGFRWGVYSLALEIGGITGRVWNNDDGTVE
                     ILAQADSSAIMAKFIQEIRKGPTPFSKVSYLDVKLSNFPPYSDFKIAN"
     gene            29312..30238
                     /gene="yidC"
                     /locus_tag="VQ543_000491"
     CDS             29312..30238
                     /gene="yidC"
                     /locus_tag="VQ543_000491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HET2611271.1"
                     /translation="MKSIKRFAFSAMGVAMLLVLTGCVNVDKTTGQPTGFIWNTIGAP
                     MAEAIKYFATDKGLGFGVAIIIVTIIVRLIILPLGIYQSWKATLHSEKMNALKHVLEP
                     HQTRLKEATTQEEKLEAQQALFAAQKEHGISMFGGVGCFPILLQMPFFSAIYFAAQHT
                     EGVAQASYLGIPLGSPSMILVACAGVLYYLQSLLSLHGVEDEMQREQIKKMIYMSPLM
                     IVVFSLFSPASVTLYWVVGGFMMILQQFIVNYIVRPKLRKKVREELAKNPPKASAFSK
                     PSGRKDVTPEQPTAITSKKKHKNRNAGKQRSR"
     gene            complement(30313..31107)
                     /gene="pflA"
                     /locus_tag="VQ543_000492"
     CDS             complement(30313..31107)
                     /gene="pflA"
                     /locus_tag="VQ543_000492"
                     /EC_number="1.97.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001288284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate formate lyase-activating protein"
                     /protein_id="HET2611272.1"
                     /translation="MSEETIDYGQVTGMVHSTESFGSVDGPGIRFIVFLQGCHMRCQY
                     CHNPDTWAMESNKSRERTVDDVLTEALRYRGFWGNKGGITVSGGEALLQIDFLIALFT
                     KAKEQGIHCTLDTCALPFRNKPRYLEKFDKLMAVTDLVLLDIKEINEEQHKIVTSQTN
                     KNILACAQYLSDIGKPVWIRHVLVPGLTDRDDDLIELGKFVKTLKNVDKFEILPYHTM
                     GEFKWRELGIPYSLEGVKPPTADRVKNAKKLMDTESYQDYMKRVHG"
     gene            complement(31233..32483)
                     /locus_tag="VQ543_000493"
     CDS             complement(31233..32483)
                     /locus_tag="VQ543_000493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000856498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate decarboxylase"
                     /protein_id="HET2611273.1"
                     /translation="MKTPFINREELEAIVAEFPTPFHLYDEKGIREKARAVNQAFSWN
                     KGFKEYFAVKATPTPAILKILQEEGCGVDCSSYVELLMSHKLDFLGSEIMFSSNNTPD
                     KEYAYARELGATINLDAFEDIEHLERVAGIPEIISCRYNPGGVFELGTDIMDNPGEAK
                     FGMTKDQLFEAFAILKEKGAKTFGIHSFLASNTVTHLYYPELARQLFELAVEIKEKLG
                     ISLDFINLSGGIGVNYRPDQEPNDIALIGEGVRKVYEEVLTSAGLGQVKIFTELGRFM
                     LAPHGALVTRVTHKKETYRTYLGVDASAVNLMRPAMYGAYHHISNVTHPDGPAEAVDV
                     VGSLCENNDKFAVNRELPHTEIGDLLVIHDTGAHGFSMGYQYNAKLRSAEILYTEEGK
                     ARQIRRAERPEDYFATLYGFDFEE"
     gene            complement(32550..33377)
                     /gene="purR"
                     /locus_tag="VQ543_000494"
     CDS             complement(32550..33377)
                     /gene="purR"
                     /locus_tag="VQ543_000494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004242125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pur operon repressor"
                     /protein_id="HET2611274.1"
                     /translation="MKLRRSDRMVVISNYLINNPYKLTSLNTFAEKYESAKSSISEDI
                     VIIKRAFEEIEIGHIQTVTGAGGGVIFTPSISSQDAKEMVEDLRTKLSESDRILPGGY
                     IYLSDLLSTPAILKNIGRIIAKSFMDQKIDAVMTVATKGVPLANAVANVLNVSFVIVR
                     RDLKITEGSTVSVNYVSGSSGDRIEKMFLSKRSLKAGSRVLIVDDFLKGGGTVNGMIS
                     LLHEFDSELAGVAVFADNAQEEREKQFDYKSLLKVTNIDVKNQAIDVEVGNIFDEDK"
     gene            complement(33644..34585)
                     /locus_tag="VQ543_000495"
     CDS             complement(33644..34585)
                     /locus_tag="VQ543_000495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exoribonuclease YhaM family protein"
                     /protein_id="HET2611275.1"
                     /translation="MKISHMKKDELFEGFYLIKSADLRQTRAGKNYLAFTFQDDSGEI
                     DGKLWDAQPHNIEAFTAGKVVHMKGRREVYNNTPQVNQITLRLPQAGEPNDPADFKVK
                     SPVDVKEIRDYMSQMIFKIENPVWQRIVRNLYTKYDKEFYSYPAAKTNHHAFETGLAY
                     HTATMVRLADAISEVYPQLNKSLLYAGIMLHDLAKVIELTGPDQTEYTVRGNLLGHIA
                     LIDSEITKTVMELGIDDTKEEVVLLRHVILSHHGLLEYGSPVRPRIMEAEIIHMIDNL
                     DASMMMMSTALALVDKGEMTNKIFAMDNRSFYKPDLD"
     gene            complement(34575..35831)
                     /locus_tag="VQ543_000496"
     CDS             complement(34575..35831)
                     /locus_tag="VQ543_000496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000444769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA recombination protein RmuC"
                     /protein_id="HET2611276.1"
                     /translation="MESLLILLLIANLAGLFLIWQRQDRQEKHLSKSLEDQADHLSDQ
                     LDYRFDQARQASQLDQKDLEVVVSDRLQEVRIELHQGLTQVRQEMTDNLLQTRDKTDQ
                     RLQALQESNEQRLEQMRQTVEEKLEKTLQTRLQASFETVSKQLESVNRGLGEMQTVAR
                     DVGALNKVLSGTKTRGILGELQLGQIIEDIMTPAQYEREYATVENSSERVEYAIKLPG
                     QGDQEYVYLPIDSKFPLADYYRLEEAYETGDKDEIERCRKSLLASVKRFARDIRNKYI
                     APPRTTNFGILFVPTEGLYSEIVRNPVFFDDLRREEQIIVAGPSTLSALLNSLSVGFK
                     TLNIQKSADHISKTLASVKTEFGKFGGILVKAQKHLQHASGNIDELLNRRTIAIERTL
                     RHIELSEGEPALDLLHFQENEEEYED"
     gene            complement(35833..36495)
                     /locus_tag="VQ543_000497"
     CDS             complement(35833..36495)
                     /locus_tag="VQ543_000497"
                     /EC_number="2.7.6.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000006147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine diphosphokinase"
                     /protein_id="HET2611277.1"
                     /translation="MSEYKLSENNWTRVAVFAGGDRGHYRTDFDGFVGVDRGSLWILE
                     EDLPLALAVGDFDSVTEEERQVIQKRAQYFVQARPEKDDTDLELALLTIFKQNPQAQV
                     TIFGALGGRIDHMLANVFLPSNPKLASYMHQIEIEDGQNLITYCPEGISQLEPRSDYD
                     YLAFMPVRDSQLTILGAKYELTEENFFFKKVYASNEYIDREVSVTCPDGYVVVLHSKD
                     RR"
     gene            complement(36458..37114)
                     /locus_tag="VQ543_000498"
     CDS             complement(36458..37114)
                     /locus_tag="VQ543_000498"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HET2611278.1"
                     /translation="MSQYKIAPSILAADYANFEREIKRLEATGAEYAHIDIMDGHFVP
                     QISFGAGVVEALRPHSKMVFDCHLMVSNPEHHLEDFVRAGADIISIHVEATPHIHGAL
                     QKIRSLGVKPSVVINPGTPVEAIKHVLHLVDQVLVMTVNPGFGGQAFLPETMDKVREL
                     VALRDEKGLNFEIEVDGGIDDQTIAQAKEAGATVFVAGSYVFKGDVNERVQTLRKQLD
                     "
     gene            complement(37125..38003)
                     /gene="rsgA"
                     /locus_tag="VQ543_000499"
     CDS             complement(37125..38003)
                     /gene="rsgA"
                     /locus_tag="VQ543_000499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="HET2611279.1"
                     /translation="MQGQIIKALAGFYYVESDGQVYQTRARGNFRKKGHTPYVGDWVD
                     FSAEENSEGYILKIHERKNSLVRPPIVNIDQAVVIMSVKEPDFNSNLLDRFLVLLEHK
                     GIHPIVYISKMDLLEDGGELDFYQQTYGDIGYDFVTSKEELLPLLTGKVTVFMGQTGV
                     GKSTLLNKIAPDLNLETGEISDSLGRGRHTTRAVSFYNLNGGKIADTPGFSSLDYEVS
                     TAEDLNQAFPEIATVSRDCKFRTCTHTHEPSCAVKPAVEEGTIAPFRFDNYLQFLSEI
                     ENRRETYKKVSKKIPK"
     gene            complement(38596..39369)
                     /locus_tag="VQ543_000500"
     CDS             complement(38596..39369)
                     /locus_tag="VQ543_000500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell surface protein"
                     /protein_id="HET2611280.1"
                     /translation="MRKKLVNSLMCAVVLSGFPIATYANEKNIGPNITVSNGQTRLSI
                     PEKNGVEVIQSEENRVVYEVKEAAKIETSDGDMVAPIVVDSRITSINNQVVQGKTVYT
                     ADLEKATFVEEGYNKLAKPTNILDHIFGIQKVHAYTQNITTHQSQFDSTYSVELYTVV
                     HWVSYDGGVQKNITKISGGVDFHERDIEIESSSVEVRQGGWYSSQQKWFHPGARSSWE
                     YSTGFSKVGPGENRVVTNYTVNLIRYGDRWSAYLQNNPW"
     gene            complement(40059..40931)
                     /gene="rsmA"
                     /locus_tag="VQ543_000501"
     CDS             complement(40059..40931)
                     /gene="rsmA"
                     /locus_tag="VQ543_000501"
                     /EC_number="2.1.1.182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (adenine(1518)-N(6)/adenine(1519)-N(6))-
                     dimethyltransferase RsmA"
                     /protein_id="HET2611281.1"
                     /translation="MRIADYSVTKAVLERHGFTFKKSFGQNFLTDTNILQKIVDTAEI
                     DDQVNVIEIGPGIGALTEFLAERAAEVMAFEIDHRLVPILADTLRDFDNVTVVNEDIL
                     KVDLAQHIQNFKNPDLPIKVVANLPYYITTPILMHLIESGIPFSEFVVMMQKEVADRI
                     SAQPNTKAYGSLSIAVQYYMTAKVAFIVPRTVFVPAPNVDSAILKMVRRPVPAVAVED
                     ENFFFKVSKASFTHRRKTLWNNLTGYFGKTEEVKDKLTKALDQAGLSPSVRGEALSLE
                     EFASLADALKGQGL"
     gene            complement(41182..41400)
                     /locus_tag="VQ543_000502"
     CDS             complement(41182..41400)
                     /locus_tag="VQ543_000502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000429598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2611282.1"
                     /translation="MENMTNPLLLVQIRVHGYLLDFASSEGQRQKHYRLKNLPQTVEL
                     TVDDVEEDVDLTLPENRSYQEADFFDTQ"
     gene            complement(41468..42109)
                     /locus_tag="VQ543_000503"
     CDS             complement(41468..42109)
                     /locus_tag="VQ543_000503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2611283.1"
                     /translation="MIDIQGLEKKFNDRAIFSGLNLKLEKGKVYALIGKSGSGKTTLL
                     NILGKLEKIDGGRVLYQGKDLKTIPTREYFRDQMGYLFQNFGLLENQSIKENLDLGFV
                     GQKISKVERLERQVGALEKVNLGYLDLEQKIYTLSGGEAQRVALAKTILKNPPLILAD
                     EPTAALDPENSEEVMNLLVDLKDENRIIIIATHNPLVWNKADEIIDMRKLAHV"
     gene            complement(42111..44141)
                     /locus_tag="VQ543_000504"
     CDS             complement(42111..44141)
                     /locus_tag="VQ543_000504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000825281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HET2611284.1"
                     /translation="MKRLFILISMVLVSLYMVITSVDHREEILFGNYPSVDVTGMMIN
                     QPVASREEVTEVLSHLAVEHNSLIARRIVEPNEAGETLFTYATYGEGELPEGLTISSK
                     ESAETSDLLGSYLIVSGSLDGVSLQTTLKELGYQGFVSNGEDPFSIVLLLAATPMVLL
                     SLAIFLLTFMSLTLIYRIKSLRQAGIRLIAGESLFGVALRPVLEDVRQFICSVLVSSL
                     LGLGILWYQGALFMATVQLVIIALLLYGLTLAGISTLLSVVYLLGLQENSLVDLLKGK
                     LPLKRMMTLMMVGQLLAVLVVGSSATALLPHYREMQEMERASNKWSQSSDRYRLSFGW
                     SSAFADEEGTRKDNREWQTFTEERLANTDSFYIMSNVDNFSDGAEVDLDGNRLSDYTP
                     SGNVIYVSPRYLIEEKITVSSEFMDKMQNLSEGEFGLILPESLREQSTYYQRLFTDYL
                     QNFSSESVEVTSQKYYLPQVSLAFTETGQERFLYNDGYKTTRQYLKDPIIVVLTPQAT
                     GTRPVAGMLWGTTANSALKLDRYGDSITALKEQGLYHKVSYLVKSQLFFAKVLNDKRV
                     EFYSLLIGTILTLSTAILLFDSMNLLYFEQFRRELMIKRLAGMTIYELHGKYLLAQGG
                     VLLLGLVLSSILTRDGLISALVVALFTLNALLILVRQDKKEEAGSMAVLKGK"
     gene            complement(44410..45309)
                     /locus_tag="VQ543_000505"
     CDS             complement(44410..45309)
                     /locus_tag="VQ543_000505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000904853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET2611285.1"
                     /translation="MLIGQKIKEIRIEKGVSRPYFCGDEQELTVRQLSRIESGASQPS
                     LPKLAYIARRLGVPVYSLMPDFSALPPAYLELKYQILREPIYGKEEEYDKKEACLEEI
                     YKTYFDNLPKEEQLACEVLQACLDTSRTRRPEYAELILEEHMSQIIEKEVYSTNDMLL
                     IRLFFYQMLIRKDLAKFINQIEKLMLFLLEQKKVTKLENFFIIRDTLISGMCCLEKVG
                     VTDCFNDYLSCLQEIMDKTQDYQKKPLVFMFLWKQALREERDFSLAESFYQSSKTFAK
                     LIGDGFLVKKLTEEWQEDVKKYL"
     gene            complement(45381..45941)
                     /gene="rnmV"
                     /locus_tag="VQ543_000506"
     CDS             complement(45381..45941)
                     /gene="rnmV"
                     /locus_tag="VQ543_000506"
                     /EC_number="3.1.26.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000660004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease M5"
                     /protein_id="HET2611286.1"
                     /translation="MKEKISQVIVVEGRDDTVNLKRYFDVETYETRGSAINAQDIERI
                     QRLHQRHGVIVFTDPDFNGERIRRMIMTAIPTVRHAFLKRDEAVPKSKTKGRSLGIEH
                     ASYEDLKTALAQVTEQFEHESQFDISRSDLIRLGFLAGADSRKRREYLGETLRIGYSN
                     GKQLLKRLELFGVTLAEVEEAMKSYE"
     gene            complement(45941..46714)
                     /locus_tag="VQ543_000507"
     CDS             complement(45941..46714)
                     /locus_tag="VQ543_000507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000575597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HET2611287.1"
                     /translation="MIFDTHTHLNVEEFAGREAEEIALAAEMGVTQMNIVGFDKPTIE
                     RALELVDEYDQLYATIGWHPTEAGTYTEEVEAYLLDKLKHPKVVALGEIGLDYHWMTA
                     PKEVQEQVFRRQIQLSKDLDLPFVVHTRDALEDTYEIIKSEGVGPRGGIMHSFSGTLE
                     WAEKFVDLGMTISFSGVVTFKKVTDLQEAAKELPLDKILVETDAPYLAPVPKRGRENK
                     TAYTRYVVDFIADLRGMTTEELAVATTANAERIFGLDSK"
     gene            complement(47019..47912)
                     /locus_tag="VQ543_000508"
     CDS             complement(47019..47912)
                     /locus_tag="VQ543_000508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001816585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1542 domain-containing protein"
                     /protein_id="HET2611288.1"
                     /translation="MVAQDPKAQDSTKPTAEKSTVKAPAQRVDVKDITHLTDEEKVKV
                     AILQANGSALDGATINVAGDGTATITFPDGSVVTILGKDTVQQSAKGESVTQEATPEY
                     KLENTPGGDKGGNTGSSDANANAGGGSQAGGSAHTGSQNSAQSQASKQLATEKESAKN
                     AIEKAAKDKQDEIKGAPLSDKEKAELLARVEAEKQAALKEIENAKTMEDVKEAETIGV
                     QAIVMVTVPKRPVAPNAAPKTTSAPQATAGTMQDVTYQSPAGKQLPNTGSASSAALAS
                     LGLVVATSGFALLGRKTRRRK"
     gene            complement(48196..48330)
                     /gene="rpmH"
                     /locus_tag="VQ543_000509"
     CDS             complement(48196..48330)
                     /gene="rpmH"
                     /locus_tag="VQ543_000509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L34"
                     /protein_id="HET2611289.1"
                     /translation="MKRTYQPSKLRRARKHGFRNRMSTKNGRRVLAARRRKGRKVLAA
                     "
BASE COUNT        13991 a        10914 c         9042 g        14527 t
ORIGIN      
        1 taaagctatt atatcagctt tccagaggag cgacaagaaa cagcaaactt atatatagcg
       61 gaatgaaata aggaaagtca aatcgatttt taacaatgtt ttagaagtag atatgtacta
      121 ttctagtttc gatctattat agttggttga gtttggaata gtacgctgta gctgctaaaa
      181 catttctaga aattaatttg actttcctaa tagagttgtt catatcttat ttcaagctac
      241 tatatataat ctaaaaactt gaatcaaaaa tcgaaaaagt agcggatttc tccactgctt
      301 taacagctta ttcttcaatt tcgatttcaa gttcatcgcc taagtcaagc ggaacttctt
      361 cattcactgc ttcttctttc tttggctcat cttttttgtt ttcagtatct tgttctgaaa
      421 cttcttctcc atcaatcaag ccaaatttag aacggacttg cttatcaatt tcatcaaaga
      481 tttctgggtg ctctgccaag tatttcttag cattctcaga accttgccca attttttcat
      541 ctttgtaaga ataccaagcc cctgcttttt tgataatatc caaatcgctt gcaatcttca
      601 aaagctcacc agtcttagaa attccttctc cgtacataat ttcaactacg gcttccttaa
      661 acggtggagc taccttattt tttacaacct taatcttagt ttctttaccg acattggttt
      721 ctttttggtc accagttccc ttaatttgtg tattaccacg aacatccaag cggactgaag
      781 catagaattt caaagcacgt ccgcccggtg ttgtttctgg atttccaaac atcactccaa
      841 ctttttcacg caattggttg ataaaaatgg caattgtttt ggttttattg atagaggcgc
      901 caagtttacg catggcctgg ctcatcatac gagcctgcaa accaacatgg ctatctccga
      961 tatctccatc aatttccgca cgaggaacaa gggcagcaac tgagtcgact acgacaagat
     1021 caactgcacc tgagtcaatc aattttcccg caatctcaag accttgctct cctgagtctg
     1081 gttgagacaa gagcaattcg tcaatattga caccaagggc cgcagcataa gctggatcaa
     1141 gggcatgttc cgcatcgata aaagcagcaa tcccaccttc tttttgcgct tgtgcaactg
     1201 catgaagggc aaccgttgtc ttaccagatg actctgggcc atagatttcg atgatacgtc
     1261 ccttaggata accacctgag ccaagggcaa tgtcaagagc taaagaacct gagctcatca
     1321 cttgcacctt ttgctccgca cgttcaccca aacgcatgat tgatccttta ccaaagtctt
     1381 tctcaatcaa tttaagagcg tcattcaagg ccttttcacg ttctgcccca aatttttttg
     1441 aaatttcttc taattttttt ggttttttcg ccattctatt ctcctacatt ctaatgatcc
     1501 tcagacctat ctactattat atcaaaaatt agtcacttaa taaagccttg cgaactaggt
     1561 taaaggcatg cataaccgca atgtgacgta catctgctcg gcttctgcct ccaatattaa
     1621 ccttgataac ctcagttcct tgatcttgcg ccaagcctat gaagactgtc ccaactgggt
     1681 gtccttctag gctatctggt cctgccactc cagtcaaact aattccaaaa tcagactggg
     1741 tcttgcttcg tgcctgctca gccatcttct gagctgtaaa ttcagacacc acaccatgtt
     1801 cttccaaatt cttggcagga atatccaaca tccttgattt ttcctccaag ctataggtca
     1861 caaaaccacc cttaaatata cttgaaattc cagaaaaatt cgccacggta gcttggaaaa
     1921 gacctgccgt caaactctct gcagccgcga tggttttccc ttgccttttc agttcttcta
     1981 ccacaatgct ggctaaacta gtttcttccc cataaccata gcaaaagtct cgtaaagaaa
     2041 ttccttcgaa agtctggcag tccaagattt gattttccaa gatatccagc gcttgattcg
     2101 cctcttcttg actgctagcc tttgttgaca gacgtagagt gacttctcct gtcttggcat
     2161 aaggggccaa ggtaggatcg acctgattat caattaaatc agccaaaatc gtaaccagct
     2221 ggctctcgcc aatcccaaag aaacgaagaa ctcgggaata cagcttgctc cctgtcatca
     2281 acttgggtag aagtaggttt aagaccatgg gtttcaattc acttggcgga cctggaagga
     2341 cgacataggt cactccgtct acttctaatt ttcctccaac agccagtcct gtttcgtttg
     2401 gcagtggaat cgctccttct acaatttgag cttgtctttc gttattcggt gttcgggcat
     2461 agtctggtcg cagggcaaaa aagatatcca acttctcctg agcctgagga tcaaagacta
     2521 atgctttccc taaaaattta gctagggttt gtttggttag gtcgtcctca gttggcccca
     2581 aaccgcctgt caaaatcacc agactgctac gttgactggc aatctcaagc aaagacaaga
     2641 gacgaacttc attgtctcct acagccgtct gaaaatatac atctacccca atctcagcta
     2701 gtttttccga caaaaactgg gcattggtgt tgacaatctg tcctgtcaaa atctctgttc
     2761 caacagcaat gatttctgct ttcatgtttc ctcctaccta tctattcgta tttttttgaa
     2821 aaaatcgcag gaattttcct acgattgatt ttttatttgt atcaaaagtt aattatcttc
     2881 atcaccaaca ggtgctctgc caaataaatc ttcaaataaa accgcattgg tttcaagctg
     2941 agtaacttct tcttgtccca aagaacgtcg gagtatattt tgcatttcca acatatgtgc
     3001 tcttgaaaca atctggtaag aaacaccttg aagtatctct ccttcaccct gcaactgctg
     3061 agtttcaatg gttttaaatg aatctttata gcctagcaag ttagggatac tttttgcaga
     3121 caaatcaata ttggtctgca tattgtcact caaagctttt agaatctctt gataatgacc
     3181 aacgctattt aaactgagag ctttttccat gactttttga ataacttcac gttgacgttt
     3241 ttgacgacca taatccccct caggatcttg gtaacgcatt cgtgcataga ctagggcttt
     3301 ttctccccca atatgttgct ccccaacacc gatagaaata gtattaaatt cttcttggtc
     3361 actgatagaa attgggaaac ctaggatatt attgactgta atacctccta ctgcatccac
     3421 tagtttttgc aaccctctca tattgaccat cacatagcga tcaatatgga tattcatcat
     3481 tttttgaatg gtttctatag caagctctgc tccaccatct gcatatgctg agttcagttt
     3541 cgcttcatga gcctgaccat tccctgattc aatgcgcgtc agaatatccc gctctaaact
     3601 catcattgtt gtttttttcg ttttaggatt cactgtcatc aagatcatgc tatcacttct
     3661 accgacccaa gtttcagttc gttcaacatt tccggtgtcc actcccatta acagaatggt
     3721 tagaggttca gtcgcttcaa taaccttggt ttcttcgccg atttttttat aggttttagc
     3781 taaggtttct gtcccttgtt gataaatagt ataagcaaaa acacctactc ctactacagt
     3841 tacagaaagt aaagctagca ccattccaat aattttttta accatatttc tactaaccta
     3901 tcagtttacc catcaagtaa acatcgataa atttcccttc ttctatatat gccccacgct
     3961 cttggctacc ttcaatgaca aagccatgct tttgataaag atggactgct gcttgattac
     4021 gagtttggac agtcagttgg agacgacgca gaatgccact tgcttgtgcc cactctatcg
     4081 cttcttctag caacaaactt cccaagccat tattccaata tctttttcca atcacaatga
     4141 agagatctcc aatatgacgg actctcttac gctgatcagc tgtaatattt acaataccag
     4201 caattttgcc atttaagaat gcaagtaagg ttatctgatt gtccgaacta gcttgcttgt
     4261 tgaggaatat ttccatctcc tcactagtca agagaatacc atctccgtct aggctggtaa
     4321 agtctgtctc caaactcaca cgatttaaaa aggccactaa ttcagctgca tctttgggct
     4381 ctgcttccct aatgagcaat tcatactcca tattgaagct cctctaacaa tttctcagca
     4441 cgcaaaccct ttgcctgaaa atttaaacgg cgtccatctg cttcttttag aatttccaat
     4501 tctaaataag catctggcaa ggcatctcct aagagatttc cccactcaat aacagtcacg
     4561 ccgccaccaa agataaactc atccaagtcg atagaatcag catctccttc aatacgataa
     4621 acatctaggt gataaagtgg aagtcgacct tcatactctc tcacgatagt ataggtggga
     4681 cttttaatca tttgagaaat ctgtaatcct tttgcaagtc ctttagtaaa ggtcgtttta
     4741 cctgcaccca gttctccagt taagattaaa acatcattct ttgctaatag atggcccaaa
     4801 cgctccccta aggcttgcaa ctcttcttca ttttttgtgt acatactctt attataccaa
     4861 aaacttttct tttgtgtcta ttttcctact aaacttatca tcataacatc cataaaaaac
     4921 aggctttctc taaaagaaaa tgagcgtaac aatgaccaat acaagatctc ggaaaatatg
     4981 accataaaag gaaacttcct tcttaaccga atttgggaca agataggctg caaaaaacaa
     5041 gcccagtcca atataaatca gaagtgagac aatggtcatt ggatttctta agaaaagaag
     5101 tgttgctaaa atagtcacca acactgtctt ttttctgtct agcatagcaa gaaaatcgcg
     5161 cacgtatttt ttcaagggta aaaaaatcag caaatctagc ccaaatagga aaaagaagga
     5221 tggcaataaa aagtcaacta attcttgctg cagcgtattt ttgatgaaca agttatctga
     5281 caaaacaaga acagctccta acaaattaat taagagtaac atactgtaaa aaagcttcac
     5341 cgacttctta ctggctagga cactatggac ttcttgctta cgggtataaa gataatttac
     5401 tccagcacag attcctgaaa cgaaaaccat gctcccgatg aaaaaagctg tactttgttt
     5461 aaaggacaag atgcattcct tccataggaa acagctactc aaactgattt gaattaaagc
     5521 taacaaaaat aagattctca ttgatttcat cttctctctc ccttcctacc aatcattata
     5581 ctaggagaaa agagagaact gtttctaatc ttctcaaatg tctctttaag acgctaaaca
     5641 aacactagag actaatactc aatgaaaatc aaagagcaaa ctaggtagct agccacaggt
     5701 tgctcaaaac actgttttga gattgcagat agagctgacg tgatttgaag agattttcga
     5761 agaatataaa tttgaaatca tgaaaatccg tcaaacgggt ggttgttttg tctcgcacct
     5821 cacggagcga gacggactca gagtcacata attataaggc tgatagtatt aatctaacta
     5881 tcagccttac aggttattta acgtttcaga aaaactataa tgtcaagatt aactaaacag
     5941 tatctaattc cttcaaataa ttttctatct tcatcagcat taaaggattg ttataaatct
     6001 tgcatagctc tcttgcttct atataataat ttttgacttg ttctctgtct agaaatttgg
     6061 ctccagcatt tcctacaaga ataagtagag gagccaattg gtagcttgtc tgtctttgtt
     6121 tacagagttc gatagtctca agagcttctt ggatggcttc attatatttt tcctttgata
     6181 ctaggtagtg agcgtaattg taacgaactc tgatgtagcc aaataaaaac tcttgatgct
     6241 caaaattttt tgtctgatat aactccatca aatgagagta gtttacctca tattcttgtt
     6301 cacgacccac taaggaatag aaattagata gagtattcaa cgcctttaaa taaatcaaag
     6361 tatttgagga gacttttaat aatatatttt ccaatgaaga aattgcttca cacttactgt
     6421 catattgaca gaagtcaata atagctttaa tccattcaag gtaagttcgg tcttctagtg
     6481 ttagaaaagt acttcgttca atctctattc tataaatata ttccaaattt tcataatttc
     6541 tatcatctaa taggcgagca gataattgct tgaaattaga gaggttagat ttaatttcaa
     6601 tttgttcatt aaaaaaataa tctaatggca cttcgagtcg ttgtgagagt ttgaacaaaa
     6661 ggtctgcgga gggaatgaaa taccctctct caattttact aatctggctc tattcacaaa
     6721 ttccttctgc aagagtttgt tgggagagtc tcaactcttt tcttttcaat ctgaatttct
     6781 ctgcgagtgt attcattaaa gataataaac cttcctattt gcttaatttc attataaaat
     6841 ttttagttca aaatagcaag ttaaaggaat aaataattct ttgcggtaat aaacaaaaaa
     6901 aagtcaaaaa ttacataaaa atgcttggct aaataaaata tatttgttaa aataaggata
     6961 atgaaaaaga aaagggtttc acgaatgaag aaaaatcgtg gaattcaaaa attagctata
     7021 ttagtattac taggtgtttt tatgtttagt aacacaattc cttaccaaca gtttattcag
     7081 aagaatagac aattggagat tcgagtccaa tcgcaaaaga agtccaatgg tcttgatgtt
     7141 gggaaggctg attgatttta tattacttta aaattcaact atttagagaa aggtattctg
     7201 atgagagctt gtaacaatac cagatagata taagaatgga gatgtttgat aaaatgcttt
     7261 catagctaac caactgttga aaattatgag ttacaaaatc taaagtattt aagattggtt
     7321 tataaaatta ggtctctgcc tgtagaaagg aacgtgcagt tagaaaggag gaaaaaatag
     7381 gatactataa ttcagactga gatttctaat taaaatatat agttgcattt cgctcatttt
     7441 cataatattt cattcagagg agtaataata tgttaaaatt tagaaaagta gttgcatcat
     7501 cccttgccgt tttggcattt agtttggctc ttcctgtttt ggcagtttct caccgtggtg
     7561 gcgagtggac ctatggaggc catcatgatc caaataattg gggagcattt tcgaattatt
     7621 atcatggttc acagtatcac tgggcctatg ttggaagtaa tggacgtaac aatcaaaaaa
     7681 cagtttatgc aggagcacgt agtgcggcct atgcgtttgt taatacaaat tttggggagc
     7741 aagttacatt tgatgcggga tggtaaagaa taattgaaga agattctttt atcaatagtt
     7801 cagtaagctt gttagtttat agagggcagg ggtatttctg ccctctgttt tagaataagg
     7861 aatgcactat gaaaaaatta tttatactca tatccaacct gcttgctagt ttgttctttg
     7921 tttgggtatt taccatttgg actgatacat atgtctccta ttattacccc aacgttgttg
     7981 tacatgattc ttcccctgaa acaacttttc agcatgttgc tacacgcttg gaaaaactag
     8041 cagaagaaac agatagcttt attgcgattc aacaccaaga tcctaactca gaaggtacta
     8101 cagttttttc ttatacgacc tttggggacg gaaagttgcc tgatgggctt caggaaaaaa
     8161 aactagaaga tgctcaaagt agtagtgttg aaacaaacta ttttgtattc gatggacacc
     8221 tagatattca cttgctaagg gaggagctaa gtcaacttgg cttgactaac atgaacctga
     8281 caattccatc taaactatct acgttaatgg ctatctttag taacggattt cagttaatca
     8341 gtctattgat tttcatctta acctttatag cactgacttt aattagtcaa attagccaat
     8401 tacggtcgtc gggcattcgc ctcatttcag gagagaaacg gtggtccatt ttccttagac
     8461 cagttggtga ggatttgaaa gggatagctg ttggtttcag tttagctggc gtgctcgcca
     8521 ttcttatgca aaaaattctg tcgcttccaa cgcaatccct aatgaccata ggagcaggct
     8581 tgctcagtta taatctcatc ttgttgtcga tctccctgtt tttcgctcaa ctcttcgcag
     8641 ttgggataaa aaagatacac ctgatgcaga ttataaaagg gcaagtgcct gtcagaggaa
     8701 tcattagttt gattttaatc ggtcaactat tagcgattat tattgtaacg ctgggaatag
     8761 ggagtagctt aaagtattcc caagcctggc aacagcatcg gattggacaa gaggcttgga
     8821 gtcaggaaag gcaactgatt accctatcaa tcagccgtga aggaacgagt cctggttttg
     8881 atgaacaagc tcaaaggaaa ctcagaactt ggtatcaatt gatggatctg gctgtttcag
     8941 aacaaaaggc tttcttatct agacaccagt taattgaccg tactttgcaa aatggcatgg
     9001 cttcctccaa aaacttgata acctctacag aatggcacga ttacaacccg aatggcaatg
     9061 tccttatcgt cacaccgcaa tacttggagc gtcaaaacat tcctgtagat acaactattg
     9121 agcaaaagat gaatcacctt gatgtagggg agtttgtctt attgctgcct gaacacctcc
     9181 gttcagagga agaacattat aaatctgttt ttgaagacga cttaaccagt cgcatgtcta
     9241 gtcaagatga acgacagcaa atgactgcta cggtaggtta tttagaatca ggtcaggatc
     9301 gttttgtgta taatacgacc cctatttctt accagcagtt tttgaaagat ccaatcatca
     9361 ttgttataac accccaatca actggtccac agtccatttt gttttggata gacgcagtac
     9421 agaactacgt tctctttaat caattgtctg atgcccagga gcttatccag agacaaggca
     9481 ttgaaaattg ggtctcagaa atgcaaacag gttaccacaa ctacatcaca ttattggata
     9541 atattcagag ggaacgttgg gtaatgctag caggagctgg gcttgggatt gcaacttcaa
     9601 tcttgttgtt taacactatg aataggctct actttgaaga atttagacgt gccattttta
     9661 tcaaacgcat tgcaggtctc aggttcttag aaatccatcg cacttatctc tttgctcaac
     9721 tgggtgtgtt tttactggga tttgttgcga gtgtatttct tcaggtagag ataggagttg
     9781 ctttcttagt cttgttactc tttactggtc tatctctttt acagttacat gtccaaatgc
     9841 agaaagaaaa caagatgtcc atgcttgttt tgaagggagg ttaatatgat tgaacttaaa
     9901 caggtgagta aatcttttgg agaacgagag ttattttcga atctttcaat gacatttgag
     9961 gctggaaaag tctatgcctt aattggttca agtggtagcg gaaaaacaac cttgatgaac
    10021 atgattggga aattagaacc ttatgatggg acgatttttt accgaggtaa agacttggcc
    10081 aattataaat cgagtgattt tttccgtcac gaattgggct acctcttcca gaactttggc
    10141 ttaattgaaa accaaagtat tgaagaaaac cttaagctag gtctcattgg tcaaaagttg
    10201 agtcggtcgg aacagcggtt gaggcagaag caggctttag aacaggtcgg cctgacttat
    10261 cttgacctag ataagcgcat ctttgagtta tcgggcggag aatcgcaacg ggttgccttg
    10321 gcaaaagtta tcttaaagaa tccacccttt attctggcag atgagccaac agcttcaata
    10381 gacccagcaa cttctcagtt gattatggag attctgctat ctcttcgaga tgataatagg
    10441 ctaatcatta tcgcaacaca taatccagca atttgggaga tggctgatga agtgttcacg
    10501 atggatcgtc tgaaataaaa atccttgttt ttaattgcac gatgagttac tgaaatatta
    10561 tcatgaatca ataattggag ttaatttaga attgtacttt attaatattg aggtaacttt
    10621 ttcttgataa aggaagaaat agtggagagg aagttagaat gaaaaaattc gacaattata
    10681 ttgttgagaa gccttgcgat tctaattcag ataaactgca aaaaatctta ataattgaaa
    10741 atttggtaga tgatattttg caatttcctc tcagaatcaa taatagtgta ggagagattt
    10801 tcctcctaca accgtttcaa aagaaaacta tctttattcc atgttatttt gaggaagata
    10861 ttgtgaaagt caaagatgat gataaagttg agtggaattt gttagaattt caaaaattta
    10921 gagcattttt ggcttagtaa tctgtgttga aggctcaaaa cctatggtaa aaaagtcgct
    10981 ttgaaaacgt attgcctcca aagatttagt taaataatga tttaacacaa aaagaaatta
    11041 ttgaagttct ggaaagatgt tgtttcagta ttgagaaaag gtgggaaaaa cttgcgattt
    11101 tcacagagaa aggaagaaaa agtatagaaa tatagtcaat tgaaacaaga acaggacaaa
    11161 agaacctttt gtgccatatt tttctccttt cgctttacaa ttggcttgaa cacctttatt
    11221 gtatcgcgtt tggagttttt ttggtataac cttcgacgcg cacccgcata gcgggtgttt
    11281 ttttgtctcg cacctaacgg agcgagacga actaatagtc acttaatcaa aaaacgcacc
    11341 atatcaaaaa ctaaaaagtt tgatatcatg cgtcatgtct taaactaatt gactatactt
    11401 tctattcaaa tgagctttta accaattgat tgagccaatc cactcttaaa accaaagagc
    11461 aatttctcgc ttagctgact cttctgaatc tgaaccatgt acaacatttt ggataacctc
    11521 attttctcca gcagcttttg caaaatcacc tcgaatagtg cctggtaaag cttcttctgg
    11581 acgagttgca cccatcatgg tccgccaagt ttcgattact ttgggaccag aaatgacacc
    11641 cacaagaact ggacctgaag tcatgaattc acgaatcggt gggtaaaaac tctgaccaac
    11701 caagtcctga tagtgctggt caatcaactc ttctgaaact tgtgaacgaa actccaattt
    11761 ttcgattgta aatccacgtt gttcgatgcg ctttaacact tcacccacta gccctctttt
    11821 tacaccatct ggtttgatga taaagaatgt ttgttccata cccgtctcct ttgtcagctt
    11881 ctttctttta ttttaccaca tttcgtggaa aaatggagaa agttttcaga atagagaatg
    11941 agagaacccg agggttctct cattctctat tattctactg tttcttccac agtttcaacg
    12001 gcagtatcca caactacttc tgttgtttct tcatttcctt cttcctctac tggaggatta
    12061 aggtattctt cttcgttgac agcatatggt tcaaggttac ggtaacgggc cataccagta
    12121 ccagctggga tgatcttacc gatgataaca ttttctttaa gtccaaggag atggtctttc
    12181 ttaccacgga tagctgcgtc agtaaggaca cgagttgttt cctggaagga agccgctgac
    12241 aagaaactgt ttgtttcaag tgaggctttg gtaattccca taaggactgg gcgacctgtc
    12301 gctggaactc cacctgcgat aaggacatct ttgttggcat ctgtaaagtc attgatatcc
    12361 atgagggtac ccatgagaag atctgtatca cctggatcca tgacacggac tttacggatc
    12421 atttgacgaa ccattacctc gatgtgtttg tcaccgattt ctaccccttg gctacggtaa
    12481 actttttgta cttcaccgag aaggtacgtt tcaactgaca agacatcacg aactgcaagg
    12541 agacgttttg gttggataga accttctgtc agagcagcac cacgcgctac ttggccccca
    12601 acttcgacac gcatacgagc tgtaaatgga acgacatatt caccttcgcc agtttcaccc
    12661 ttaacaaaga ctttcttggt acgagttgat gcatcttctt cgatagcagt aacttctcct
    12721 ttaacctctg tgataaccgc ttccccttta ggattgcggg cttcaaagat ttcttggaca
    12781 cgaggaagac cctgagtgat atcggtattt gaggcaaccc cacctgtgtg gaaggtacgc
    12841 attgtaagct gtgtaccagg ttccccgata gattgggcag caatggtacc aactgcttca
    12901 ccaacttcaa ccgcatcacc agtcgccaag ttgataccgt aacagtgacg gcagacaccg
    12961 tgacgagtgt tacatgtaaa tacagaacgg atagtcactt cttccacacc agcattgaca
    13021 atttcacgcg ccttgtcttc tgtaatcaat tcatttggac caataatcac tgcaccagtt
    13081 tctggatgtt taacagtttt cttagtgtaa cgaccgttga gacgctcttc gagagactcg
    13141 atcatctctt ttccttctgc gatagaacgg atcaagagac cacggtcagt tccacagtcg
    13201 tcctcacgga tgataacgtc ttgggcaacg tcgaccaaac gacgagtcaa gtaacctgag
    13261 tcggctgtct taagggccgt atcggtcata cctttacgag caccgtgagt tgagaagaac
    13321 atttccaata ccgacaaacc ttcgcggaag tttgaaagga ttggcaattc catgatacgt
    13381 ccattcggag cagccatcag accacgcata ccggcaagct gtgagaagtt tgagatgtta
    13441 ccacgggctc cagagtccat catcataacg attgggttct taggatcttg gttagcaatc
    13501 aagcgtttct caagtttttc acgggcagca cgccattcag ctgtaacagc attgtaacgc
    13561 tcgtcgtctg tgatcatacc acgacggaat tgtttggtga tttgctcgac acgtttgtgt
    13621 gattcttcaa tgatttcagc cttgtcatca acgactggga tatcggcaat acccactgtc
    13681 aatcctgcaa gagttgagtg gtggtaaccg agattcttca tgcggtcaag tagggcagaa
    13741 gtttctgtcg tacggaaacg tttgaagatt tcagcgatga tatttccgag gtttttcttc
    13801 ttgaacggag ggttgagctc aagattgctg atagcttcct tgatatctcc accaagtggc
    13861 aagaagtatt tagctggaac accttctgtc aagttggcat tgtttggttc ttgcaagtat
    13921 ggtagcccct ctggcatgat atcgttgaag agaattttac caactgttgt aagcaagacc
    13981 ttatgtcttt gctcttctgt ccaaggcttg ttgaggctgt ctgttgcgat accaacacgt
    14041 gagtggaggt gaacataacc attgcggtaa gccataaccg cttcgtcacg gtctttgaag
    14101 accattcctt caccttcgcg accagcttct tccatggtca agtagtagtt acccaaaacc
    14161 atgtcctgag atggagtaac taccggtttc ccatctttcg gattcaagat gtgctcagca
    14221 gctagcatga ggatacgagc ttctgcttgt gcttcttctg aaagtggtac gtggatggcc
    14281 atttggtccc cgtcaaagtc agcattgtag gcttcacaga caagtgggtg caagcgaaga
    14341 gccttaccat caatcaagac tggctcgaag gcttggatac ccaaacggtg aagggtcggt
    14401 gcgcggttca aaagcactgg gtgttcttta atcacttctt caaggatatc ccagatacgc
    14461 tcatctccgc gttccaccaa gcgtttagct gctttgacgt tttgcacgat atcacgggca
    14521 acgatttcac gcatgacaaa tggtttaaag agttcaatcg ccatttcacg tggcacacca
    14581 cattggtaca tcttaagagt tggaccaacg gcgataacgg aacgtcctga gaagtcaaca
    14641 cgtttaccga gcaagttttg acggaagcgt ccttgtttac ctttaagcat gtggctcaat
    14701 gatttcaatg gacggctacc tggtcctgtg attggacgac cacgacgacc attgtcaatc
    14761 aaagcgtcaa ctgcttcttg aagcatacgc ttctcatttt gaacgatgat acctggtgca
    14821 tttaactcaa gcaaacgagc caaacggttg ttacggttga taacacggcg gtaaaggtca
    14881 ttcaagtcag atgaggcaaa acggccacca tccaactgca acattggacg aagatctggt
    14941 gggataaccg gaagaatgtt aagaatcatc cattcaggtt tgtttccaga cttgtaaaag
    15001 gcatccaaaa catccaaacg acggatggct ttgacacgtt tttgtccagt agctgttttc
    15061 aattcttctt tgagttcagc aatttctttt tcaagatcta cttgcttcaa aaggtcttgg
    15121 atggcttccg cacccatctt ggcaacaaat gaaccataac catattcacg caagcgctct
    15181 cggtattcgc gctctgtcat gatagacttg tgctcaagtg gtgtatcctt aggatcaatc
    15241 accacataag ccgcaaagta gataacttcc tcgagggcac gagggctcat atcaagggtc
    15301 aagcccatac ggcttggaat ccccttgaag taccagatgt gagatacagg agctttcaat
    15361 tcgatatgtc ccatacgctc acgacgaact ttcgtacgcg ttacttcaac cccacagcgg
    15421 tcacaaacaa ttcctctgta acgaatgcgt ttgtacttac cacaagcaca ttcccagtct
    15481 tttgtaggac caaagatcac ttcatcaaag agtccttcac gttctggttt caaggtacga
    15541 taattgattg tttcaggttt tttgacttct ccataagacc atgaacggac tttacttgga
    15601 gaagctaggg tgatttgcat acttttaaaa cgatttacat caaccactat ttcttccctt
    15661 tctattctaa gtgaactgct tattcttgtt cagcagcttc ttctgttgct tccgcttttg
    15721 ttgctttctc agcttcttca gcttcaaagg ctgctttagc ctcttgagct gctttttcgc
    15781 gggctttttc aaggtcatct acgtggatga catcttcgtc cattccttca tccaagtcgc
    15841 gaagttccac ttcttggtca tcttcgtcta ggacacgcat gtcaagacca agagattgca
    15901 attctttgac aagaactcgg aaggattctg gaacacctgg ttttggaatt ggtttgcctt
    15961 ttgtaatagc ttcataggct ttcaaacgtc cgttgatatc gtccgacttg taagtcaaga
    16021 tttcttgaag gacatttgac gcaccgtagg cttcaagagc ccaaacctcc atctcaccga
    16081 aacgttgtcc accaaactga gctttacctc cgagtggttg ttgggtaaca gttgagtaag
    16141 gtccgactga acgcgcatgc aatttatcgt caaccatgtg gtggagtttg atcatgtaca
    16201 tgactccaac agaaacacgg ttatcaaatg gttcacctgt acgtccatcg taaaggattg
    16261 tcttggcatc gctatccata cctgcttctt taacagttga ccaaagatct tcagaacttg
    16321 ctccatcaaa gactggtgtc gcaatgtgaa taccaagagt acgagctgcc ataccaaggt
    16381 gaagctccat aacctgaccg atattcatac gtgatggcac cccaagtggg ttcaacatga
    16441 tgtcgactgg agttccgtct ggaaggtaag gcatgtcttc tacaggaacg atacgagaga
    16501 caaccccttt gtttccgtga cgtccggcca ttttatctcc gaccttaatc ttacgttttt
    16561 gagcgatgta aacacgaacc aacatgttaa cacctgattg caactcatct ccatttacac
    16621 gtgtaaagat cttaacatca cgaacgacac catcggcacc gtgtggtaca cgaagagaag
    16681 tatcacgcac ttcacgagac ttgtctccaa agatagcgtg caagagacgt tcttcagctg
    16741 aaagatcttt ctcaccctta ggtgttactt tacctacaag aatatcacct tctttaacct
    16801 cagcaccaat acggataatc cccatttcgt caaggtcttt gagggcatct tcaccaacgt
    16861 ttggaatttc gcgagtgatt tcttcaggcc caagctttgt atcgcgcgtt tctgattcgt
    16921 attcttcaag gtgaacagat gtgtagacat cgtccttcac caagcgttcg ctcatgataa
    16981 cggcatcctc gaagttgtaa ccttcccaag tcatgtaggc aacgattggg ttttgtccaa
    17041 gcgccatttc tccattttcc atagaaggtc cgtcagcgat gaaatcgcct ttttcaacga
    17101 catcaccaac ttttacgaga gtgcgttggt tgtaagcagt acctgagttt gaacgacgga
    17161 atttttggat gtggtaaaca tccaatgaac catcttcacg acgaacttct accttgtcag
    17221 catctgcgta agtaacttta ccatcatact gagcaatcac agccgcacca gaatcgtggg
    17281 ctgcttggta ttccatacca gtaccaacgt aaggtgcctg aggattaatc aatggcacag
    17341 cctgacgttg catattggct cccatgaggg cacggttgga gtcatcgttt tccaagaaag
    17401 gaatacatgc tgtcgcaacg gcaactacct gttttggtga aacgtccatg tagtcaacaa
    17461 tattagctgg atactcttgg ttgacccctt ggtgacgtcc catgacaatc ttctcagcaa
    17521 aggttccatc ttcattcaga ctagagttag cctgagctac agtatattca tcttcttcat
    17581 cagctgtcaa ccaaacaatt tcgttcgtga caacacctgt ttcacggtca accttacggt
    17641 atggtgtttg aacaaaacca tatttgttca agtgtccgta agatgacaag ttattgatca
    17701 aaccgatgtt aggtccttca ggtgtctcga ttggacacat acgaccatag tgagtgtagt
    17761 gcacgtcacg tacttcatat ccagcacggt cacgagtcaa accaccaggt cctaaggctg
    17821 acaaacggcg tttgtgagac aactcagaaa gcgggttgtg ttggtccatg aactgtgaca
    17881 actgtgatga accaaagaat tctttaactg cagctgttac aggacggata ttgataattt
    17941 gttgtggtgt caagacttca ttgtcctgaa cagacatacg ttcacggaca ttacgttcca
    18001 tacgagaaag tcccaaacgt acttggttgg caagcaattc accaaccgca cggatacgac
    18061 gatttccaag gtggtcgata tcatctacac ggccaagtcc ttcagccaag ttgaggaagt
    18121 agctcatctc agcaaggata tctgcaggag tcaccgtacg aaccttgtca tctgggttag
    18181 cattaccaat gatcgttacg acgcgatctg gatcagttgg agcaacaacc ttgaattttt
    18241 gaagaacaac aggctcagtc acaacggctg catcgtttgg gatgtagaca atcttgttca
    18301 agtcgccatc caaatggctt tcaatgcttt caatcacgct acgagtcata atcgtaccag
    18361 cttctaccaa gatttctcca gtttcagggt ctaccaatgg ctctgcaatg gtttggttga
    18421 gcaaacgtgt tttaacattg agttttttat tgattttgta acgaccaact gctgccaagt
    18481 catagcgacg tgggtcaaag aagcgagcca caagcaagct acgtgagctt tcagctgtct
    18541 taggctcacc tggacgaagg cgttcgtaaa tttctttcaa ggcttcgtct gtacgagagt
    18601 ccattggatt cttgtggata tctttttcaa cagtgttgcg aaccaattcg ctgtcaccaa
    18661 agatatcaaa gatttcatca tcacctgaga aaccaagagc acgaaccaag gttgtaaatg
    18721 gaatcttacg agtacggtcg atacgagtgt aggtgatatc ttttgagtcg ctttcaagtt
    18781 ccaaccaagc tccacggtta gggataacag ttgaaccata gcccacctta ccatttttgt
    18841 ctactttgtc gttaaagtaa acacctggtg agcggaccaa ctgagaaacg ataatacgtt
    18901 caccaccatt gatgatgaaa gtacccattt ctgtcatgat tgggaaatca ccaaagaaaa
    18961 cttcttgggt cttgatttcg cctgtttctt tattgatcaa gcggaaggtt acaaaaattg
    19021 gtgctgagta gctagcatcg tggatacgag cttcttctag cgtgtatttt ggttccttga
    19081 tttcatatcc aacaaattcc aactccattg tgtctgtgaa gtttgaaatt ggcaatacat
    19141 cttcaaacac ttccttaaga ccgtggtcta ggaaagcttt gaatgagtca gtttgaattt
    19201 caatcaaatt tggtaagtca agaacttctt tgattcttga aaaactacga cgggtacgat
    19261 gtttcccgta ttgaacgtca tgtcctgcca agatgattct cctttgtaaa taagttccaa
    19321 gccttgtcaa tcaggctttt ctaatcgcca tatggttgta aaccccttat caccgtgtcc
    19381 tcttgacgaa ttttcagaat ctttaagcct ctgttacaaa tgctcaaaat cttgaaaaaa
    19441 agcacaaaaa gagcagctaa atctgacttt ttcagaagat ttaactgctg tgagccttgt
    19501 ctggacaata tttcagacaa aacctacgac aaatgattac ccatattata ccctatttag
    19561 ctagattttt caaggggatt cagtaggttt ttggtaattt ttttcccata gaaaacttgg
    19621 catcacattc gaatcacgct atggtacaaa aaactgaaaa aactattgac tgaaaatcat
    19681 tttcaaggta taataataaa cgttaaggcg gtatagccaa gtggtaaggc acggctctgc
    19741 aaaagcttga tcgtcggttc aaatccgtct accgccttct ataacttgat ttatcaggtt
    19801 tcaaatgaac agaaagccca atttgaaggg ctttttttat tttccctcga ataaatacgt
    19861 ataactttaa aaacttttgg agcgagtttg tggcagagtt ctttccatgg cataattccc
    19921 ttttgaaatc aattgaaaaa agcttcgtca cgcctggtga caaaagcctc tagtttattc
    19981 tgtttcttct tctatttcga cttctgtgat ttggactttt accttggtaa cacgtccatt
    20041 cttcacttta tcattggtta agataaactg tttgttttgg ctgaccaatt catagctgag
    20101 tttctcagtc gttggaatgg ttcccactcc tgtcaaataa taaccagcga tagtatcaac
    20161 gtcatcactt tccagttcaa cattaaagta attattgaaa tcattgaggg tcatagttcc
    20221 ttgaacaatg taggtatcct cgccaatctg atgaacatct attgctgctt tgtccgtttc
    20281 atcatcaatt tcaccaacaa tttcctctaa gaggtcttcc aaagtcacca aaccagccat
    20341 accaccgtat tcatccagca agattgccat ttgtctttgg gtatttcgca gttcttttag
    20401 caagtcatcc acaaaaatag tttcaggtac aaaaagtgga tcttgtaaaa ttctcttcca
    20461 aacaatattg tcaaaaccgt ccacaaagcc tgccttaagg agactcttgg tgtgaatgat
    20521 tccaattaca ttgtccttat ccccatcata aaccgggata cgagaataat tttgttttaa
    20581 aatactttgg ataatggctt gactatcatc ctgaatatcc accataaagg catccgttcg
    20641 aggaaccata acctctcgtg ccatcagttc atcgagcgaa aagacacctt gtaacatctc
    20701 aatctcatca gcatccaatg tttcttcact atttgtcagc atataggcaa tttcatcacg
    20761 ggtcatcttt tcatccgcat catcgaatga cataggagtc aaatggctca agaaattggt
    20821 cgaagcagct aaaagccaaa caaaaggact gactagtttt ccgatcccaa tgataaccgg
    20881 cgctgtacga attgccaagg catcctttag attaagagcg attctcttag gatataattc
    20941 cccaaaaacg atggaaatat aggtcaaaaa tgccaaggat agaaaagttg ccacggcttg
    21001 tgctgtttcg ccattcccaa gccaagaggc aatcacacgt cctagagtat cagttaaact
    21061 cgcccctgat aagattgtaa tcagggtgat tcctacctga atggttgata aaaagtggtt
    21121 aggattttct agtaccttca gcaggcggat gtagcgtctg tctccttctt ccgccttttg
    21181 ttcaactcgg gcacgattaa gagaaaccat ggccatttct gtggctgaga aaaaggcatt
    21241 taataccgtc aagataaaca ataaaacaaa ttgtagcaac aaattctgac tacttgggtc
    21301 ttccatagtt cttctcctaa aatagtatct tatcctttat tatatcacaa aatttaatcc
    21361 aatacatatt atttttttct tagcgtaact tccatctctc tcccaaaact ggaagttagt
    21421 ctaagacgga tttccactga tttcacgcgt ttttctcata ctaaaagcta ggttgtggga
    21481 aactggaagt tagttttaga agttactatt ttttcttagt acctgttcta gccctgctta
    21541 aactagtaaa aagaactcct acatccataa gtgacatagg agtttaggct tatcttttac
    21601 tgagttacag ttacttctcc agttcggtaa tccagttgaa gtcccttttg aacattggga
    21661 actagaacat tgaattccaa ttctccatcc gaagacttgg cttcaatctg tgaagctgag
    21721 ggaactaaat cctcgtttga agcgtagtaa agggttacac ggtaacggac acgcttgttt
    21781 tggtccaagg ctttacgcac cttgctttca tagtagtttt gaccagtcga atactcggct
    21841 tgtgcctgat ttgcccaggc tgtctgaaca gcaatgtttt taggattgct tgttgaggca
    21901 tcaaaaccat ccaaaccacc gattaaggca tagcctaaca aatgacctct atcgactgca
    21961 tgggtataag agccctttag attcttgacc tgatgccaac ctggaggagt ccaagaagtt
    22021 gaaccattcc cagtttcttt acgattcttg tactgacgag tggccttaga caagagggca
    22081 ttagctacgg ttggaacagt ttccttaccc actgtctttg ttttattgtc agcgtagggc
    22141 ttacttgaaa ccttggcatc tagatttgtt ttattaccat tgacgataaa agcacctgag
    22201 ccattccact ccagactccc ctttatttga ctcttgactg cgtctgttaa gacactctct
    22261 gccaatgctt gactaggagc ttcaggcgct tgttttttct gactaagctt ggttttagga
    22321 ctattagctg tcgactgcat ctgcttgata taatagctcc ctgtagacaa aagcaataac
    22381 actagcagtc cgattagtgt ctgtcttgtt tttttgttca tatttctcct tatctttaga
    22441 aaaaggctgg ttctccagcc taatttcctg taaatttatg aatcaattcc tgccattttg
    22501 ctggagacag gatagcccat gaatcttgac ccttgcccaa gattccataa cctaccatta
    22561 aaccgattcc tagagccaga gtacctaaaa tcagtactat gatgactaaa agtaaacgct
    22621 tgactacgta gcttgatttc ttattcatct tcatcacttg cctcaatccg ctgaatctta
    22681 gcacctagct gcgccaactt ctcatggaaa ccgtagtaac ctctatccaa gtgaaccaat
    22741 ttaccgacca cagtttctcc ctgtgctacc aaacctgtca aaatcaaagc tgcactggca
    22801 cgaaggtcag ttgaaagaac ttctgctccc tgcaaaggct gtccaccaac aatacgagct
    22861 gtatcacgga taatctcaga atgcaagccc atgcggcgca tctcttctag gtgttggaaa
    22921 cgattttcaa aaactgtctc caccatggtt gattcgcctt ttgcaactgt catcaaggct
    22981 gtaaattgag cctgcatatc tgttggaaat cctgggtggg gcaaggtttt cacatgaaca
    23041 gcttttagat tttccagttg agaacgaaca cgaattcctt cgtcttcttc aattacttca
    23101 acacccattt caagtaactt ggcaatcaag ggacggttgt gctcccagac agcgtctcga
    23161 atcaagacat caccaccagt catggcagca gctaccataa aggttcctgc ttcgatacgg
    23221 tcctggacta cattgtgagt cgtaccatga agtttctcaa caccagtaat ggttatagtc
    23281 tctgtaccag cacctttgac cttggctccc atttcattaa ggagaatggc taagtcaaca
    23341 atctcaggct cacgcgcagc attctcaatc actgtcaccc catcagccag agtcgctgcc
    23401 atcatcaagt tctgcgttgc accaacactt ggaaagtcca tatagatatg agcaccatgc
    23461 aagcgttctg cctttgcttc gatgtaacca gctgtctgac taatcttaac ccccatagct
    23521 tccagacctt tcaaatgaag atcaatagga cggctaccaa tcgtacaacc acctggcatg
    23581 gataccttgg catgacccac acgggcaagg attggcccta atacaacgat ggaggcgcgc
    23641 atcttactga catacttgta aggggcttcc tcagtgatgt cgccagtagc atccaccttg
    23701 acaagatgag cttcctcatc aaagtcaacc ttggcattca aaccaccaac tacctgattc
    23761 ataataaaga catccgacaa aatcggaaca ttctgcaaga cggtctttcc ttcacttgct
    23821 agaatagtcg ctgccaacaa gggtaagact gcattttttg ctccctcgat cgtcacgctt
    23881 cctaccagac gattatcgcc accttgaacc acaattttat ccatactcgt ttcctttact
    23941 cttgatttta taataatcct ctaagcgctt cttgccacaa atgatacagg ctaataaaga
    24001 aagaactcag gatgtagcct atgacaatgc taaaaaaggc tactaataca cgaacttttc
    24061 ttgtattctc agctgtcact tttaaaacct tttcccatct aacaagatcc tttaaaaggt
    24121 aaaaactcac ataaataaag agcatatgac tacttagagt gaataataat tgaaccattt
    24181 gactattata ccatcttctc tgtttgtgcg ctagtttgga aacttcactc aaaaattagg
    24241 gattgttttt caagtaatca atcgcatctt gtagggtttt aacgggcacg attttcatat
    24301 ccgtcttgat tgttttagcc gcttctaggg ctgtttggta gttgtttttc gcgtccggat
    24361 gcgccttttg ttcttcttcg ctaacagggt tatcaggagc aaagaaaata gcagcacctg
    24421 ccctagccga agctacaacc ttcttatcaa tacctccaat gtctcccaca ttaccatcgc
    24481 ggtcaatggt acctgtaccg gcaacaatac gaccattacg aagatctggg tgagctattt
    24541 gagtatagat agctagacta aacatgagac cagcacttgg gccgccaata ccagctgttg
    24601 aaaagctaat tgggacattg ctgattacct ctgtacgatc aatcaagccg attccaatcc
    24661 cattttttcc attttccaag gtgataatct tcccttctgc agacttggtt tgcccatcct
    24721 cttcataggt gaccttgacg gaatccccta atttttgaga actgacgtaa tcaatcaagt
    24781 ctttggaact atcaaaggtc tgatcattga ctgctgtgac tgtatcagag atattgagaa
    24841 tccctttaaa ggttgaatta tccgtcacat tcaaaacata aactccaaag tacttgagtt
    24901 cgatatcctt accagctgtt tttagtcctt gatacttggc catattttgc gatgtttgca
    24961 tgtagaattg attgattcgc ataaattcaa catcggaaga accacctgta gtctcctgag
    25021 cactacgaat atctgtaaaa ggtgtcaacc aagcataaat catatgagct aaagtagcat
    25081 gttgaacacc aaccgtaacg aattgatagg caccagcttc cttatcttct gtgtcattta
    25141 ctttaaggac ttggcgaata tcttccgaac cacctggaac ctctatataa taaggcaagg
    25201 gcactacaaa tgccaagaaa gtcacaatca aggccgcaat gacgtataag ggccatctaa
    25261 tctttttttt catttcttat ttcctccaaa atactctcgg gaacatagca ggcaatatcc
    25321 tgaccaaact tcaaaagctc tctaacgcct gatgaactga tatagagatg ttcaggtcga
    25381 ctatgtaaat aaatagtctc tatatcagaa gacagctgat gattgtagta atcaaaactg
    25441 gcttcatatt gcaaatccga cgcattcctc aaaccacgca ctagacaagt agcacccaat
    25501 ctttttgcaa catcgaccac caattcatca tgagaagcca cgacttcaac attttccaaa
    25561 tgtcccaaag ccttttctag cccccgttta cgattttcaa gagggagaaa tccttgtttg
    25621 tggggattaa aaaaaatacc cacacaaagc ttatcaaaaa gtctgctcgc ccgttcaatg
    25681 atatccagat gcccatttgt catcggatca aatgagcctg tgaataagcc aatcttatct
    25741 gacatagact gtcaccttac taattccata aatcttttcc ttccagatac ccagacaggc
    25801 aatttcttct ggaagttcaa cggtcttatc cgtctcgcac acaaccataa catcttcaga
    25861 aaaaagctct ctctcagcca ttttttcaat atctgctacg atttgttcct tggcataggg
    25921 agggtctaag aaaacgaggt caaattcccc agatacctgt tccaatgccc tttctgcatc
    25981 cattttgagg agttgaaatt ttccaacttc cttggtcatc tggatatttt cagccacgat
    26041 ggtctgagcc ttacggtctc gctccaccaa aacagcactg gacatgccac gcgatactgc
    26101 ttcgatagat aaaccaccac tacctgcata aaggtccaag actcgtccca cttcaaagta
    26161 gggaccaatc atgttaaaaa tggctcccct aaccttatcc gaagtaggtc ttgttgtctt
    26221 gccttctagt gtcttgaggg gacgtccccc atagattcct gatacgattt tcatactgtt
    26281 tattatacca aattatagac aaaaagagaa agaaaaccga accttgcggt tcgattctct
    26341 acaaaatatt ttcgtaagta tcgcggactt cttgaggcca aacacttgtt tgcacttctc
    26401 cgatgtgtct cttgcgaagt aggaacatgg ccatacgaga ttgtccaatt cctccaccga
    26461 ttgtcaatgg gaataggcca ttcaacaaag acttgtgcca ttccaattct aagcggtctt
    26521 catcacctgt aatttccacc tgacgtctaa gagtttcttc atctacacga attcccatag
    26581 aagacaactc aaaggctcca cctaaagact cattccagac aagaatatca ccatttagac
    26641 ccttgtagcc attctcagac tcgcttgtcc agtcatcata gtctggtgca cgtccatcgt
    26701 gcggtttacc atctggcaac tcgccaccga taccaatcaa aaagacggct ccaaattctt
    26761 tacaaatcgc attttcacgt tctttaggtg tcaagtctgg gtagcgttct accaattctt
    26821 ctgtatggat aaaggtgatt tgttttggca agatagactc gatgtcatag cgggcttcaa
    26881 cagctagctc agtcaggcga atagccttat aaatcttctc aactgtttct tttagataaa
    26941 cgatgttacg cttaccattt gggataacct tctcccagtc ccactggtca acataaacag
    27001 agtgggttgc atccaaggaa tcctcatctg gacgaagggc tttcatgtgg acaaagagac
    27061 cctctccttc accaaagcca aaacgagcca aggtgtggcg tttccattta gcaagtgagt
    27121 gcaccacttc ataagtagca tcagggattt ggagaacctt gaccgatact ggattttcca
    27181 caccagacag gttgtcctgc attccgtcac cgaccttact caagatagga ccttgaactt
    27241 cgacaacttc tagcttatct ttcaaatact gggtaaaagt gtttttgaca aaggaaattt
    27301 cttcttgttg atggataaaa cttttcttca tagacaactc ctcaaaaatt taataaacgt
    27361 attatacacc tatttccaag aaaagaaaag agaaaatttt aaaaaaatca gtgtcactca
    27421 aaacactgat ttcatagacc ttttagtcat tgcgaccaaa gatacgtaga atacttagga
    27481 aaagattgat aaaatcaaga tagatgctga gagccattga caccacccag cctgtcgcta
    27541 cacgaccttg tgattgttca taggcgaggc gaatcttttg gttatcccaa gcaatcaacc
    27601 ctgaaaaaac caaaaccatg gctacgctaa tcatataatc aaagaagcca ctagccaaga
    27661 aaatattgac taccatagca atcagtaaac caatgagagc tgccatcatt gctcgaccaa
    27721 tcccactcaa gtctttcttg gtaaaaatac caactgccgc catgacaaag aagagaaggg
    27781 cgctcgatac aaaggcagat aaaactgtac ccggagtata gaaagccacc acaaaactaa
    27841 gggtaaagcc gtttaaaacg gagtaaagta aaaatactgg aagagcagct ggactatttc
    27901 ttgaagccat gctactggca acgaaaacca aagccaactc cgcaaaagta gcaatggtca
    27961 accagagacg cccctgcatc aacaagtaaa ccaactgaga ctgaaagacc gtcaacataa
    28021 ggcctgatac caaagcagat agtccgattc ccagaccaac aaaggcataa accttagcgt
    28081 aaaattgatt gagacctgca cggtcatgta taatagtgtg attcatcctt ttctcctttt
    28141 ctgtgaacat ctttccttga ttataacaaa aaaagttaaa attagcttaa atggaagatt
    28201 aaaataccgg ctgcaactgc aacattcaaa ctctcggcct gccccttcat gctaatatgg
    28261 accaactggt ctgcactttc agccataagg ggactaattc cttgaccctc atttcccata
    28321 actagtacaa aattttctat agaaggcagt tctctgtaat caacagaatc tttagatagg
    28381 gttgttgcta gcactgggat agctaccttt ttagtttcgt caagaagcgc ttgactagtc
    28441 atccggtaaa tgggcagatg gaaatgacta ccttgcatgg aacgtagggt tttgagactg
    28501 tagatgtctg ccgacttatc tgaaacaatc actcctgtaa aacctgctgc atccgcagtt
    28561 cgaatgatag ttcctacatt accaggatct tgcacatctt ccaaaaacaa gaacttgccc
    28621 tgactcaaat cagcttgtcc tacttcttct ttttgaacca cggcaacaat tccctgtgga
    28681 gtctgagaat ccgccaaatc tagcaaaata tcctctgaaa tccagacagt ttgcggaaaa
    28741 gcagctaact gatttcgata attttctagg gcaaagattt tctcaatcgt cactccagct
    28801 tggacagctt cttcaaacaa gtgccagcct tcaatcaaat aggcagactt gcggtatttt
    28861 ttttggtgta atttcttggc attttttacc acagaattgg cttttgaggt tataatagtc
    28921 atagaaatat tataacacaa tcaaaggggt ttggtatgca aaaggttaga atgattgccc
    28981 aaggtagggt gcagggagtc ggctttcgtt ggggtgttta tagcctggcc cttgaaatcg
    29041 gtggcatcac aggtcgggta tggaataacg acgatggcac agtggaaatc ttagcccaag
    29101 cagactcatc tgctatcatg gcaaaattta tccaagaaat ccgaaaagga ccgacacctt
    29161 tttcaaaagt aagctactta gatgtcaaac taagcaactt tcctccctac tctgacttta
    29221 aaatcgcaaa ttaggtctcc agaactattg tatattttgt aaaaaaacag tagaatagaa
    29281 aggtataatt tttaaagaag gaataaaaac agtgaaatct attaaacgtt ttgcattctc
    29341 ggctatggga gtggctatgt tgcttgtctt gactggctgt gtcaatgtcg ataaaaccac
    29401 aggtcagcca acaggattta tttggaatac gatcggagcg cctatggctg aagccatcaa
    29461 gtacttcgct actgataaag gtctaggctt tggtgtcgct atcattatcg taaccattat
    29521 cgtacgcttg attatcttac cacttggtat ctaccaatca tggaaggcaa cgcttcactc
    29581 tgaaaagatg aacgctctca agcatgtcct tgagccacac caaacacgtc tcaaagaagc
    29641 aactactcaa gaagaaaaac tcgaagccca acaagccctc tttgccgctc aaaaagagca
    29701 cggcatcagc atgtttggtg gtgtaggatg tttccctatc ctccttcaaa tgcctttctt
    29761 ctctgctatc tactttgctg cccaacatac tgaaggggtt gctcaagcaa gctacctagg
    29821 cattcctcta ggttctccaa gtatgatttt ggttgcctgt gctggtgtcc tttactatct
    29881 tcaatcgctc ctttcacttc acggagtaga agatgaaatg caaagagaac aaatcaagaa
    29941 aatgatttac atgagcccac tcatgatcgt cgtcttctcc ctcttctcac cagctagtgt
    30001 cacactttac tgggttgtcg gtggtttcat gatgattctc caacagttta tcgtcaacta
    30061 tatcgttcgt ccaaaacttc gcaaaaaagt ccgtgaagaa ctagccaaga acccaccaaa
    30121 agcaagtgct ttctctaaac caagtggacg aaaagacgtt acccctgaac aaccaactgc
    30181 tatcacaagc aagaaaaaac acaaaaatcg caacgctgga aaacaacgtt cgagataaga
    30241 agaaaaaggc ttagctgatt tgctaagtct ttttgcaaat caaaagcccg atgtttccat
    30301 caggcttctt ttctatccat gtacacgttt catataatct tgataacttt cggtatccat
    30361 gagtttttta gcgttcttga cgcgatctgc tgttggtggt ttgactcctt cgagggaata
    30421 tggaattcca agttcacgcc acttgaactc acccatggtg tgataaggta gaatttcaaa
    30481 cttatcaaca tttttgaggg tcttgacgaa cttaccaagt tcaatcaagt catcatctct
    30541 gtctgtcaat cctggaacta gcacgtggcg aatccagaca ggttttccaa tatctgatag
    30601 atactgggca caagccaaga tatttttatt agtttggcta gtgacaatct tgtgctgttc
    30661 ttcgttgatt tccttgatat ccaaaagaac caagtcagtg acagccatga gtttgtcaaa
    30721 cttctcaagg taacgtggtt tattacggaa aggaagagca caggtatcca aggtacagtg
    30781 gattccttgt tccttagcct tggtgaagag agcaatcagg aaatcaatct gcaagagagc
    30841 ttctcctcca ctgactgtaa tcccaccctt atttccccag aaaccacggt agcgcaaggc
    30901 ctctgtcaag acatcatcta ccgtccgttc acgtgactta ttggactcca tagcccaagt
    30961 gtctgggttg tggcaatact ggcaacgcat gtgacagccc tgcaaaaaga caataaagcg
    31021 aataccaggc ccatctactg acccaaagct ttctgtcgaa tgcaccattc ctgtcacttg
    31081 tccataatca attgtttctt cagacatatc gttaccttcc ttgaaaacgt tttatagttt
    31141 tattatatca cgacttgaag gaaaaacaag atttttgcct attttttaga aagcaatctg
    31201 tttttcaatt tcattttcaa tctattatca gattattctt caaaatcgaa gccatataag
    31261 gttgcaaaat agtcctcagg gcgctctgca cggcggattt gacgggcttt accttcttcg
    31321 gtatagagga tttccgcaga acgtaatttg gcattatact ggtagcccat tgaaaatccg
    31381 tgggcacctg tatcatgaat taccagcaaa tcaccgattt ctgtatgagg cagttcgcga
    31441 ttgactgcaa atttatcatt gttttcacag agtgaaccaa ccacatctac cgcttcagct
    31501 ggtccatctg gatgggtcac gttgctaata tgatggtaag ctccgtacat agctggacgc
    31561 atgaggttga ctgctgaggc atccacacct agataggtac ggtaggtttc cttcttatga
    31621 gtcactcttg tgactagagc accgtgaggt gccagcataa aacgacccaa ttcggtgaaa
    31681 atcttgacct gaccaagacc tgctgacgta agaacttctt catacacctt acgaactccc
    31741 tcaccaatca aggcgatatc gttcggctcc tggtctggac gataattaac accaataccg
    31801 ccagaaagat tgataaagtc tagcgaaatg cccaactttt ccttgatttc aacagccagt
    31861 tcaaagagct gacgagccaa ctctggataa tagagatggg tcacggtatt ggacgctagg
    31921 aaggagtgaa tcccaaaagt cttggctcct ttttccttca agatagcaaa ggcttcaaag
    31981 agctggtcct tggtcatgcc aaacttagcc tccccaggat tgtccataat gtctgtcccc
    32041 agttcaaaaa cgcctccagg attataacga caagagatga tttctggaat gcctgctact
    32101 ctctccagat gttcaatatc ttcaaaggca tccaagttaa tggtcgcacc caattcacgt
    32161 gcataggcgt attccttgtc tggcgtgttg ttggaagaga acataatctc agaacccaga
    32221 aagtccagtt tatggctcat caaaagctct acataactag agcagtccac accacaacct
    32281 tcttcttgga gaattttcaa aatagctgga gttggagtag ccttaactgc aaaatattcc
    32341 ttaaagccct tgttccacga aaaagcttgg ttgacggctc ttgccttctc acgaatcccc
    32401 ttctcatcat acaagtgaaa gggagtcggg aactcggcaa caatcgcttc taactcttct
    32461 ctattgataa atggtgtttt cataagcttc cttctattct gtttgcaaag aaaggctggg
    32521 acaatcgttc caacctttag ttctatctct tatttatctt cgtcaaagat attgccaacc
    32581 tcaacatcga tggcttggtt cttgacatca atattggtta ccttcaagag tgacttgtag
    32641 tcaaactgct tttcacgttc ttcttgggca ttgtccgcaa agaccgctac acctgccagt
    32701 tctgagtcga actcgtgcaa gagactaatc ataccattga ccgttccgcc acctttcaag
    32761 aagtcatcca caatcaagac acggctgcct gccttaagac tacgttttga aaggaacatt
    32821 ttctcgatac ggtcaccact tgaacctgaa acatagttga cgctaacagt tgaaccttcg
    32881 gtaattttca ggtcacggcg cacaatgaca aaagagacat tgaggacatt ggcaactgca
    32941 tttgcaagtg gcacaccctt agttgctacg gtcataaccg cgtcaatttt ttggtccata
    33001 aagcttttgg caataatacg accaatattt ttcaagatgg ctggtgtgct aagcaaatca
    33061 gacagataga tataaccacc tggcaagata cggtcacttt ctgacaactt ggtacgcaag
    33121 tcttcaacca tttccttagc atcctgactc gaaatagacg gtgtgaagat gacacctccg
    33181 ccagccccag tcactgtctg gatatgaccg atttcaattt cctcaaaggc gcgtttgata
    33241 atgacgatat cttctgagat ggatgattta gcagactcat acttttcagc aaaagtattg
    33301 agactagtta gtttataagg attattaatc aaatagttgg aaatgacaac catccgatca
    33361 cttcttctta atttcatttc tatttcctat tccattttta ttcaaaaaat caaaaagcaa
    33421 actagaaagc tggtcgctgg tggttcaaaa cactgttttg agattgtcaa tagaactgac
    33481 aaaccctgta atatacctgc atatatacat acgacaaggc gatactaccc tagtttgaag
    33541 agattttcga agagtattca tttttgtctt ttacttatta taccatattc acataaaaaa
    33601 acgaacattc ttatcctaaa aaatgctcat ttttcttaaa ttatcaatct aaatctggtt
    33661 tatagaagga acgattatcc atagcgaaga ttttattggt catctctcct ttatccacca
    33721 aagccagagc tgttgacatc atcatcatgc ttgcatccag attgtcaatc atatggataa
    33781 tctctgcctc cataatacgt ggacggactg gacttccata ttcaagcaag ccgtggtgac
    33841 tgaggatgac atgacgaagc aaaacgactt cttccttggt atcatcgatg ccgagttcca
    33901 taactgtctt ggtaatttcg ctatcaatga gagcgatatg tccaagaaga ttacctcgca
    33961 ctgtgtactc tgtctggtct ggccccgtca actcgataac cttagctaag tcatgcagca
    34021 taatccccgc atagagcagg ctcttattga gctgaggata aacttcgcta atagcgtctg
    34081 ccaaacgtac catggtcgcc gtatgataag ccaaccccgt ttcaaaggca tggtggttgg
    34141 tcttggcagc tggataggag tagaattcct tatcatactt ggtgtagaga tttcggacaa
    34201 tccgttgcca gacaggattt tcaattttga aaatcatttg cgacatgtag tcacgaattt
    34261 ccttgacatc aactggtgac ttgaccttga aatcggctgg gtcattgggt tcaccagctt
    34321 gaggcaggcg gagagtaatt tgattgactt gaggggtatt gttataaact tctcggcgtc
    34381 ctttcatgtg gacaacctta cctgcggtaa aggcctcaat gttatgaggt tgggcatccc
    34441 agagcttccc atcaatctcg ccactatcat cttggaaggt aaaggctagg tagtttttcc
    34501 cagctcgagt ttgcctcagg tcagctgatt tgattaggta aaagccttca aatagctcat
    34561 cttttttcat gtgactaatc ttcatattct tcctcatttt cttgaaaatg gagtagatca
    34621 agcgcaggct caccttctga caactcaatg tgacggagcg tccgctcgat agctatggta
    34681 cgacggttta ataattcatc aatattgcca gaggcatgtt ggagatgttt ttgtgccttg
    34741 accagaatac caccaaactt gccaaactcg gtcttgacac tggcaagagt cttgctgata
    34801 tggtcggcac tcttttggat attaagggtc ttgaaaccaa ctgatagaga gttaagaagg
    34861 gctgataggg tacttggtcc tgcaacaata atctgttctt cccgtctcaa atcatcaaag
    34921 aagaccggat tgcgcacaat ctctgaataa agaccttctg tcggaacaaa caagattcca
    34981 aagttggttg tccgaggtgg tgctatgtac ttgttcctaa tatccctagc aaagcgcttg
    35041 acgcttgcta ggagtgactt acgacagcgt tcaatctcat ccttgtcacc tgtctcatag
    35101 gcttcttcca agcggtaata atctgccagt ggaaacttag agtcaattgg cagatagacg
    35161 tattcttggt cgccttgtcc gggtaacttg atggcatact ccactcgttc actagagttt
    35221 tcaaccgttg cgtattctcg ttcgtactgg gcaggtgtca tgatgtcttc aataatttgc
    35281 cccagttgca attctcccag aatccctcgc gtcttggttc cagagagaac cttgttaaga
    35341 gctccgacat cacgggcaac tgtctgcatt tctccaaggc cacgattgac agactccagt
    35401 tgtttagaaa ctgtctcaaa ggaagcctgt aagcgtgtct gcaaggtctt ttctagtttt
    35461 tcctcgaccg tctggcgcat ttgttccaaa cgttgctcat ttgattcctg caaggcttgg
    35521 agacgttggt ctgtcttgtc tctagtttgg aggagattat ctgtcatttc ttgacggact
    35581 tgggtcagac cttggtgcaa ttcaatccgc acttcttgca aacggtcgct gacaaccact
    35641 tccaaatctt tttggtctaa ctggctggct tgtctggctt ggtcaaagcg gtaatccaac
    35701 tggtctgaca aatgatctgc ctgatcctcc aagctcttac ttaagtgttt ctcctgccta
    35761 tcctgccttt gccaaatcag aaagagacca gctagattgg caattaataa tagaataagt
    35821 aaactttcca tcctacctcc tgtccttgct atgcagtacg accacataac catctgggca
    35881 agttaccgac acttccctat ctatatattc gttagaagcg tacacttttt taaagaaaaa
    35941 attttcctct gtcaactcat acttggctcc aagaatagtc agctggctat cccgaactgg
    36001 cataaaggct agatagtcgt agtctgaacg aggttctagc tgactgattc cttctggaca
    36061 ataagtaatc aagttttgcc catcctcaat ttctatttga tgcatatagg atgccaactt
    36121 aggattgcta ggcagaaaga cattggccaa catatggtca atacggccac ccaaggcacc
    36181 gaaaatagta acctgagcct gaggattttg cttaaagatg gtcaagagag ccaattccaa
    36241 atcagtatca tctttttctg gccgggcttg gacaaaatac tgggcacgtt tttgaatcac
    36301 ctgtcgctct tcttccgtca cagaatcaaa atctccgact gctagagcaa gaggcaaatc
    36361 ttcttccaag atccagagcg agcctcgatc cacaccaaca aaaccatcaa agtccgtccg
    36421 ataatgaccg cggtctccgc ctgcaaaaac ggcaacccta gtccagttgt tttctgagag
    36481 tttgtactcg ctcattgaca tctcccttaa agacatagga acctgctaca aaaacggtcg
    36541 caccagcttc tttggcttga gcaatagttt ggtcatcaat cccaccatcc acttcaatct
    36601 caaagttcaa acctttttca tcacgaaggg caaccagctc acgaacctta tccatggttt
    36661 ctggcagaaa ggcttgacca ccaaatccag ggttaactgt catgactagg acttggtcaa
    36721 ctagatgaag cacatgctta atcgcttcaa ctggtgtacc aggattgata acaactgatg
    36781 gcttgacacc gagtgaacga atcttttgga gggcaccatg aatatgaggc gttgcttcca
    36841 catggatact aataatatcc gcacctgcac gcacaaagtc ctctaaatga tgctcagggt
    36901 ttgacaccat caagtggcag tcgaaaacca tcttactatg aggacgaaga gcttcgacca
    36961 cacccgcacc aaaactgatt tgcggcacaa aatgaccatc cataatatcg atatgggcat
    37021 actctgcccc agttgcttct aggcgtttaa tttcacgttc aaagttggca taatctgctg
    37081 ccagaattga cggagcaatc ttgtattgag acataggttt ctccttattt tggaattttt
    37141 ttgctgactt ttttataggt ttctctgcga ttttcaattt cgctgaggaa ttgcaggtag
    37201 ttgtcaaaac ggaagggcgc aatggtacct tcttcaactg ctggcttgac agcacaggac
    37261 ggctcatggg tatgggtaca agtacggaat ttgcagtctc gactgacagt ggcaatctct
    37321 ggaaaggcct gattgaggtc ttcagccgtt gatacttcat aatccagtga tgaaaagcct
    37381 ggtgtgtctg cgattttacc cccattgagg ttgtaaaaac taacagctcg agtggtatga
    37441 cgcccgcgac ccagactgtc tgaaatttct cccgtttcaa gattaagatc tggtgcgatt
    37501 ttattgagaa gagttgattt cccaacaccc gtctgcccca taaagaccgt aaccttgcct
    37561 gttaacaaag gcaggagttc ctctttactg gtcacaaagt catatccgat gtcaccatag
    37621 gtctgctggt aaaaatccag ttctcccccg tcttccaaca aatccatttt agaaatatag
    37681 acgatgggat gaataccctt atgctccaaa agaaccaaga aacgatccag caaattgctg
    37741 ttaaaatcag gttccttgac agacatgatt actacagctt ggtcgatatt gacaataggc
    37801 ggacggacca gactgttttt ccgttcgtga atcttgagaa tatagccttc tgaattttcc
    37861 tcggcagaga aatctaccca gtccccaacg taaggggtat gccctttttt acggaaattc
    37921 ccacgcgcgc gtgtttgata gacttggcca tcactctcta catagtagaa cccagccaag
    37981 gctttaatga tttgtccctg caaaataact cctttaaaat tgttagttcc attataacaa
    38041 aaaaaagcta ttttagctta gcttctcttt acaatttcga taagtctatt ctaaaagaaa
    38101 aagatacact cacgctttag ataccaagtt ttatacaaaa ataacgaatc tacctcctta
    38161 tataaaaaca ggcgaacaga gagcctaaaa ctccctgttc gctttacttt ttctgtgtgt
    38221 aatagaaaaa acctaataaa gcaagacaaa aaatatgaat ataaactcca tacatcatgt
    38281 ggggaaagac agactctata aaatagcctg gtagatagat gattggaaat tgatagaaat
    38341 cataggtcgt tagagatagt aaacaaagaa catacataaa tactgctaca attagaaccc
    38401 atccttgctt tcgccataga aaaatcatca ataagaacag acaaagtaga tagattgacc
    38461 aatttcgcaa cataaattga aaaccataaa tcatactttc agtcgtttct ccatcaatca
    38521 catcaactac tttatagaaa ggtaaacaat agctcactaa aaaaagaagg ggactaatta
    38581 tttttttcat attctctacc atggattatt ttgcaagtaa gctgaccatc tatctccata
    38641 tcgaatcaaa ttaacagtat aattagttac tacccgattt tcacctggtc caaccttaga
    38701 aaaacctgtg ctatactccc aactacttct tgcacctgga tgaaaccatt tttgctggga
    38761 tgaataccaa ccaccttgtc taacttccac acttgaagat tctatttcga tatccctttc
    38821 atggaagtca actcctccac ttattttagt aatatttttt tgtacacctc catcataact
    38881 cacccagtga acaacagtat acaattccac actataagta ctatcaaact gactttgatg
    38941 agtagtaatg ttttgagtat aagcgtgcac tttctgtata ccaaaaatat ggtctaatat
    39001 attcgttggt ttagcaagct tattgtaacc ctcttcaaca aaagtagcct tctctaaatc
    39061 agcggtataa acagtttttc cttgtactac ttgattgttt atagaagtaa tacggctatc
    39121 cacaacaatg ggggccacca tatctccatc gctagtttct attttagctg cctctttcac
    39181 ctcatataca actcgatttt cttcagactg aatcacttct accccatttt tttcaggtat
    39241 agataatcta gtttgcccat tagaaaccgt tatatttgga ccaatattct tctcatttgc
    39301 ataagtcgca ataggaaatc ctgatagaac cactgcacac ataaggctat tgactaattt
    39361 ttttctcatg aatatatcct tcccattttc aagaggagta aaaatagcta atataagatg
    39421 aacgtttcct tatatttcag aataggatat ctatctgaaa gcaattcaca ctcctataga
    39481 taactgttcc aaatcttggc tacatatatt tcaatagttt gctacaaaaa actcctttct
    39541 aagtctattg aacatgccct tattcaccta ctaatatatc acaaaaataa ataaatacaa
    39601 gactgttttt tctactagtt ttatgataga atagtattgt tagggtaaat ttcatatata
    39661 aatgtcgagt gaaaaatcga tggagcagaa atcggtagac aaagactcga tttcgttggt
    39721 ccagccccac aaggctaatc aggtatttca cgagtttaaa aatctaatga agtgcccaat
    39781 caactactga ttcattgatt taatacgaac tatagtggat tgaacctaga aatagtacac
    39841 taaggattct aaaacgtttc tagaaattaa tttgactttc ctaatctctt tgttcatatc
    39901 ttatttcaat ctactatata taccaaaatg ctaggacaaa agtctttaaa atcagagaaa
    39961 cgcatattat caggtgttgg aaaaccttga taatatgcgt tttatcatag aaagatctac
    40021 ttcatttttt actaaaatta agtttttgtc cctgcatctt agagtccttg ccctttaagt
    40081 gcatctgcta ggctggcaaa ctcttccaag ctgagagctt ccccacgcac acttggtgac
    40141 aagcctgctt ggtccaaagc cttggtcagc ttgtccttga cctcttcagt cttgccaaag
    40201 taacctgtca agttattcca caaggtcttg cggcgatggg taaaactagc cttggaaacc
    40261 ttaaagaaaa agttctcgtc ttccactgct acagctggca ctggacggcg caccattttc
    40321 aagatggctg agtctacatt tggtgctggc acaaagactg tacgcggcac gataaaggca
    40381 accttggctg tcatgtaata ctgcacagcg atagacaagc taccgtaagc cttggtattt
    40441 ggttgagccg agatacggtc cgccacttct ttttgcatca tgaccacaaa ctcactaaaa
    40501 ggaatgccac tctcgattaa gtgcatgaga ataggcgttg tgatgtagta aggcaaatta
    40561 gccactacct tgattggcag gtcaggattt ttgaaattct ggatatgttg cgccaaatcg
    40621 accttgagaa tgtcctcgtt gactacagtc acattgtcaa aatcacgcaa ggtatctgcc
    40681 aaaatcggta ccaaacgatg gtcgatctca aaggccataa cttctgctgc acgctcagcc
    40741 aaaaactcgg tcaaggcacc aatacctggc ccgatttcaa tgacattgac ctggtcatca
    40801 atctcagccg tatccacgat tttttgtagg atattggtat ccgtcaagaa attttgccca
    40861 aaggactttt taaaggtaaa accgtgacgc tccagcactg ccttggtcac gctataatct
    40921 gcaattctca tctattctct tttctattat ctgttactac tattgtaaca cattcccctt
    40981 gtattttggg ggtgaaaatc ataccaaaaa actatctttc ctcatgaaga aagatagtct
    41041 tggaaatctt taaaagtggc cttagcgctt ctctcgaaac atacgttcat actcttcgaa
    41101 aatctcttca aaccacgtca gcttcacctt gccgtactca agtacagcct gcggctagct
    41161 tcctagtttg ctctttgatt ttcattgagt atcaaaaaaa tcagcttctt gataacttcg
    41221 attttcgggt agggtcaaat ccacatcctc ctccacatca tccactgtca gttcaaccgt
    41281 ttgaggtaaa tttttcaaac gataatgctt ttgcctttgc ccttcactac tagcaaaatc
    41341 aagcaaatag ccatgcactc ggatttgaac caaaaggaga ggattggtca tattttccat
    41401 gatgaggata tcttataaac cacctctggc actaggataa tcagataccc tgcgaatacg
    41461 gattttttca cacatgagca agtttcctca tatcaatgat ttcatcagcc ttattccaga
    41521 ctaggggatt atgggtcgca atgatgataa ttcgattttc atctttcaaa tccaccaaga
    41581 gattcataac ctcctctgaa ttttcaggat caagagctgc tgttggttca tctgccaaaa
    41641 tcaagggtgg atttttcaaa atagttttcg caagggcaac tcgttgggcc tctcccccag
    41701 ataaagtata aattttttgt tctaaatcca aataccctag attaactttt tctaaagccc
    41761 ccacttgcct ttccaaacgt tctacttttg agattttctg accaacaaaa cccaaatcca
    41821 aattttcttt gattgattgg ttttctaaga ggccaaaatt ttgaaagaga tagcccatct
    41881 gatctcgaaa atactcacga gtgggaatgg tttttaaatc tttcccctga tagagaaccc
    41941 ttcctccatc tatcttttct agctttccca agatattcag cagcgtcgtc tttccgcttc
    42001 cactctttcc gattaaggca taaaccttgc ccttctccag cttgagattc aaaccagaga
    42061 aaatcgcgcg gtcattaaat ttcttttcca atccttgaat atcaatcatc ttattttcct
    42121 ttcaatactg ccatgctacc agcttcttct tttttgtcct gccttactaa aatcaagagg
    42181 gcgttaagcg taaacaaagc tacaactaga gcgctaatca aaccatctct tgtcaaaata
    42241 ctagatagga ctaggccaag caagagaact cctccttgcg ccagtaaata cttgccatga
    42301 agctcataga ttgtcatacc agcaagacgt ttaatcataa gctcccgtct gaactgctca
    42361 aaatagagaa gattcatgga atcaaataac aagatagccg tagacagggt caaaatcgtc
    42421 ccaataagga gagagtaaaa ctctacccgt ttgtcattta gtaccttggc aaaaaatagc
    42481 tggcttttta ccaagtaaga aaccttgtga tacagacctt gctcttttag agctgtgatg
    42541 ctgtctccat atcgatctag tttcaaggca ctattagccg tagttcccca caacatccct
    42601 gcaacaggtc ttgttccagt cgcttgcggc gttagaacta caataatcgg atcttttagg
    42661 tactggcgtg ttgtcttgta cccatcatta tagaggaaac gttcctgtcc tgtttctgta
    42721 aaagctagac ttacctgtgg gaggtagtat ttctgactcg tcacttctac actttcagat
    42781 gaaaagtttt gcaggtaatc tgtaaacaat ctttggtagt aggtagactg ctctcgcaag
    42841 ctctcaggca agattagccc aaactctccc tcagacaagt tttgcatctt gtccataaac
    42901 tctgaagaaa cggtaatctt ttcttctatc agatagcgtg gtgagacata gataacattc
    42961 cctgacggtg tgtagtcact gagacgattg ccatctaggt ccacttctgc tccgtctgag
    43021 aaattgtcaa cattgctcat aatataaaaa gagtctgtat tggctaaccg ttcttcagta
    43081 aatgtctgcc actcacgatt atccttacgc gttccttctt catcggcaaa tgcactagac
    43141 caaccaaagg atagacggta acggtctgag gactggctcc atttattgct agctctctcc
    43201 atttcctgca tttcacggta gtggggtagg agagctgtcg cactcgatcc gaccaccaat
    43261 acagctaaga gttgccccac catcatcaat gtcatcatac gtttgagagg gagtttccct
    43321 ttcaatagat ccaccagact attttcctgt aaaccaagta gatagacgac acttagtaag
    43381 gtagaaatcc ctgccagggt caatccataa agtagaagag caatgatgac cagttgcacc
    43441 gttgccataa acaaggcacc ttgataccag agaatcccca atcccaaaag actggatacc
    43501 agcactgagc agataaactg tctcacatct tctaacactg gtctgagagc aactccaaac
    43561 aagctctcac cagctattaa gcgaatccct gcctgacgaa gggatttgat ccgataaatc
    43621 agggtcagac tcataaaggt cagcagaaaa atagctaaac tcagtagcac cataggggtg
    43681 gccgccaata gtaagactat cgaaaatgga tcttctccat tcgaaacaaa gccttgatag
    43741 ccaagttctt tcaaggtggt ctgtaagctc actccatcca aacttcctga cacaatcaag
    43801 taagacccta ataaatcact cgtttctgca ctctccttgg aggaaatggt cagaccttct
    43861 ggaagctctc cctcaccata agtggcatag gtaaagagtg tttctccagc ttcatttggc
    43921 tcaacgattc gacgggcgat gagactatta tgctctaccg ccaagtgact caaaacctct
    43981 gtcacctctt cgcgactagc tactggttga tttatcatca ttcctgtcac atcaacagaa
    44041 ggatagttac caaataaaat ctcttctcga tggtcaacgg aagttatcac catataaagc
    44101 gataccaata ccattgaaat caaaataaat aaacgtttca tcatttcctc caaaaagtta
    44161 cttggtcact tagtgagaag gtgaccacag tcactgcgat gttaagaagc ttattaagtt
    44221 ctttctacta gcaacatctt caaatacatt atatccgttt tttcaagaac tatcaaggac
    44281 atcaatgtcc ttaaaatcta actatttcat attattttta gcttatatct aaaaaaacag
    44341 ttctaaagac gaactttaga actgttttga tacgaggaca aggacatttt tgtcactgat
    44401 tcactatgtt tataaatatt ttttgacatc ctcttgccat tcctctgtca atttctttac
    44461 tagaaatcca tctccaatta gcttcgcaaa tgttttagaa gactgataaa atgattcagc
    44521 taaactaaaa tctctttctt ctcttaatgc ttgcttccac aaaaacataa atacaagagg
    44581 tttcttttga taatcttgag ttttatccat aatttcttgt aaacacgata gataatcatt
    44641 aaaacaatca gttactccta ccttttcaag acaacacatt cctgaaataa gagtatctct
    44701 aattataaag aagttttcta atttagttac ctttttctgt tccaaaagaa agagcattag
    44761 cttttcgatt tgatttataa atttggcaag atcttttcta atgagcattt gataaaaaaa
    44821 caaacgaatc aacaacatat catttgttga ataaacttct ttttctatga tctgagacat
    44881 atgttcctca agtattaact ctgcatattc aggccttcta gttctagaag tatccaaaca
    44941 cgcctgcaat acttcacatg ctaattgttc ttctttagga agattatcaa agtatgtttt
    45001 ataaatctct tccaaacacg cttccttctt atcgtactcc tcttctttac catagattgg
    45061 ttcacgtaaa atctggtatt tcaattctaa ataagcagga ggaagagctg aaaaatccgg
    45121 cataaggcta taaactggaa ctcctagccg gcgagcaata taggctaact tgggcaaact
    45181 cggttgcgaa gctccacttt caattcgcga cagttgacga actgtcagtt cttgctcatc
    45241 tccacaaaaa tatggacgac taactccttt ttctatccga atctctttaa ttttttgacc
    45301 aattaacatc agacgcctcc tcttctacct gcttcgaaaa atactgtgaa acttaaaaaa
    45361 ttgtaacggc tacatctttc ctactcataa gatttcatag cttcttccac ttctgccaaa
    45421 gtaaccccaa acaactctag gcgtttgagg agttgcttgc cgttagaata gccgattcgg
    45481 agagtctctc cgagatattc tctacgctta cggctgtctg cccctgctag aaaaccaagg
    45541 cgaatcaagt cgctacgact aatgtcaaac tgactctcat gttcaaattg ttctgtcacc
    45601 tgagctagag ccgttttcag gtcttcatag ctggcatgct caattcccag agaacgcccc
    45661 ttggtcttgg actttggaac agcttcatct cgcttgagaa aggcatgccg aactgttgga
    45721 atggccgtca taatcatgcg ccgaatccgc tccccattaa aatctgggtc tgtaaagaca
    45781 atgactccat gacgttggtg caggcgctga atccgctcta tatcctgagc attgatggca
    45841 gaacctcgag tctcataggt ctccacatcg aaataacgtt tgagattgac cgtatcatca
    45901 cgcccttcaa ccacgataac ttgagaaatt ttctctttca ttacttgctg tccaatccaa
    45961 aaatgcgttc tgcatttgca gtcgttgcta ccgccagctc ttctgtcgtc ataccacgca
    46021 agtcagcgat aaagtcgacc acatagcgag tataggctgt tttattttca cgaccacgct
    46081 tgggtacagg tgctaagtaa ggcgcatctg tttccaccaa aatcttgtcc aaaggtaact
    46141 ctttagctgc ttcttggagg tcagttacct tcttaaaagt caccactcct gagaaggaaa
    46201 tggtcatacc aagatccaca aacttctctg cccactcaag cgtccctgaa aatgaatgca
    46261 tgataccacc acgaggacca acgccctcac tcttgataat ctcataggta tcttccagcg
    46321 catcacgggt atggacaaca aaaggcaaat ccaagtcctt agatagctga atctgacggc
    46381 gaaaaacctg ctcctgcacc tctttgggcg ctgtcatcca atggtaatct aagccaattt
    46441 cacctaaagc cacaaccttg ggatgtttta acttatccaa caagtaagcc tcaacttcct
    46501 ctgtataagt accagcttct gtaggatgcc aaccaatagt cgcatagagc tgatcatact
    46561 catctaccaa ctccaaggca cgctcaatcg tcggtttatc aaaaccaaca atattcatct
    46621 gtgtcacacc catctcagca gccaaggcaa tttcttctgc ctcacgacct gcaaattctt
    46681 ctacattcaa gtgtgtatgt gtatcaaaaa tcatctcttc taacctcgtt ttctatcttc
    46741 tattatacca aaaaagagga ggggcaccta atttttcggt ttcccctcct ctcttcaata
    46801 gagagctatt ctgctatctt ttctatccga tattgcccat ctcctattcc acagttagag
    46861 acagaagaga ttggctacat tgatagaata ttcctattca gctaaagtat gtgattatct
    46921 tgggttctca cttttctcac ccatcactag gattgatgac ttctcaaaat cccccttata
    46981 atctaacttt aagtagagaa tagaattttc tagctgttct attttctacg tctagtcttt
    47041 cttcctagca aagcaaaacc acttgttgcc accactagac caagactagc aagtgctgca
    47101 cttgatgctg aacctgtgtt aggtaattgt ttgccagcag gtgactggta ggtaacatct
    47161 tgcattgttc ctgcagttgc ttgcggtgca cttgttgtct taggagcagc attaggagcc
    47221 actggtctct taggaactgt aaccatgaca atggcttgca ctccaatcgt ttctgcttcc
    47281 ttcacatctt ccatagtttt cgcattttca atctctttga gagctgcttg tttttctgct
    47341 tccactcttg ctaaaagttc tgctttttct ttatcagaaa gcggtgcgcc tttgatttca
    47401 tcctgcttgt ccttggctgc tttttcaatg gcatttttag ctgattcttt ttcagtagct
    47461 aattgcttag aagcttgtga ttgagctgag ttttgtgaac ctgtgtgagc tgatccaccc
    47521 gcctggctac caccgcctgc attcgcatta gcatctgagc ttccagtatt gcctccctta
    47581 tctccacctg gtgtattttc tagcttatac tctggtgtag cttcttgagt tacagattca
    47641 cctttcgcag attgttgaac tgtatctttt cctagaatcg tcactactga accatctggg
    47701 aatgtgattg ttgctgtacc atctccagct acattgattg tcgctccgtc taatgctgaa
    47761 ccatttgctt gtaaaatagc aaccttaact ttttcttcat ctgttaaatg agttatatct
    47821 tttacatcta ctctttgagc aggtgcttta acagttgatt tttcagcagt cggtttagtg
    47881 ctatcttgtg cttttggatc ttgtgctacc aattgatttc ctggaattgt aatagctgaa
    47941 ccatctttaa agacgattgt cgctgcgcca tctccagcta cttcaacttt atagtaaaat
    48001 gaaataataa caggacaaat cgatcaggac agtcaaatcg atttctaaca atgttttaga
    48061 aatagaggtg tactattcta gtttcaatct actataacat cgcttccgaa tccatttgca
    48121 tctactgaac ttttttacaa aaataaaaat cagtagactc gagttcctac tgatttttga
    48181 tagaattcgt ttggattatg cagccaaaac tttgcgtcct ttacgacgac gagctgccaa
    48241 tacgcgacga ccatttttag ttgacatacg gttacggaat ccgtgtttgc gcgcacgacg
    48301 aagtttactt ggttgataag tacgtttcac gatgaatacc tcctcataga ttttgtattc
    48361 gtttagccgg ctataaagtg atcagttact aaacatactt tactattcta tctgattctt
    48421 tcacttttgt caatagctct aggcaaatgt ttccagcttt ttcgaatgca agcc
//
LOCUS       DAVBEO010000008        46866 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 009
            SAMEA1678075-rid20185393.denovo.008, whole genome shotgun sequence.
ACCESSION   DAVBEO010000008 DAVBEO010000000
VERSION     DAVBEO010000008.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678075
            Sequence Read Archive: ERR226392
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 46866)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 46866)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980207.1
            Genome Coverage       :: 150x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:50:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 72 of 147
            Pseudo Genes (incomplete)         :: 72 of 147
            Pseudo Genes (internal stop)      :: 42 of 147
            Pseudo Genes (multiple problems)  :: 32 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..46866
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678075-rid20185393.denovo.008"
                     /strain="KS 009"
                     /db_xref="taxon:1313"
     gene            <1..781
                     /locus_tag="VQ543_000510"
     CDS             <1..781
                     /locus_tag="VQ543_000510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HET2611290.1"
                     /translation="TYYYHLKQLDKTDKDQELKAEIQSIFIEHKGNYGYRRIYLELRN
                     RGYLVNHKRVQGLMKVLNLQAKMRQKRKYSSHKGDVGKKAENLIQGQFEGSKTMEKCY
                     TDVTEFAIPASTQKLYLSPVLDGFNSEIIAYNLSISPNLEQVQTMLEQAFTEKHYENT
                     ILHSDQGWQYQHDSYHQFLEGKGIQASMSRKGNSQDNGMMESFFGILKSEMFYGYEKS
                     FQSLNQLEQAIVDYIDYYNNKRIKVKLKGLSPVQYRTKSFG"
     gene            complement(910..1113)
                     /locus_tag="VQ543_000511"
     CDS             complement(910..1113)
                     /locus_tag="VQ543_000511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000594204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET2611291.1"
                     /translation="MIKLYSPYAFLSKYLGAILLSFFCYYAKEIGCNNLTLSVWNDNE
                     GALRFYQRQGMKPQETTMEMIID"
     gene            complement(1106..2188)
                     /locus_tag="VQ543_000512"
     CDS             complement(1106..2188)
                     /locus_tag="VQ543_000512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HET2611292.1"
                     /translation="MSKLQQILTYLESEKLDVAVVSDPVTINYLTGFYSDPHERQMFL
                     FVLADQEPLLFVPALEVERASSTVSFPVVGYVDSENPWQKIKHALPQLDFKRVAVEFD
                     NLILTKYHGLKTVFETAEFDNLTPRIQRMRLIKSADEVQKMMVAGLYADKAVHVGFDN
                     ISLDKTETDIIAQIDFAMKREGYEMSFDTMVLTGDNAANPHGIPAANKVENDALLLFD
                     LGVLVNGYASDMTRTVAVGKPDQFKKDIYNLTLEAQQAALDFIKPGVTAHEVDRAARE
                     VIEKAGYGEYFNHRLGHGIGMDVHEFPSIMEGNDMVIEEGMCFSVEPGIYIPGKVGVR
                     IEDCGVVTKDGFDLFTSTSKDLLYFD"
     gene            complement(2314..3096)
                     /locus_tag="VQ543_000513"
     CDS             complement(2314..3096)
                     /locus_tag="VQ543_000513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase"
                     /protein_id="HET2611293.1"
                     /translation="MVYTSLSSKDSNYPYQLNIAHLYGNLMNTYGDNGNILMLKYVAE
                     KLGAHVTVDIVSLHDDFDENHYDIAFFGGGQDFEQSIIADDLPAKKESIDNYIQNDGV
                     VLAICGGFQLLGQYYVEASGKRIEGLGVMGHYTLNQTNNRFIGDIKIHNEDFDETYYG
                     FENHQGRTFLSDDQKPLGQVVYGNGNNEEKVGEGVHYKNVFGSYFHGPILSRNANLAY
                     RLVTTALKKKYGQDIQLPAYEDILSQEIAEEYSDVKSKADFS"
     gene            complement(3096..4439)
                     /locus_tag="VQ543_000514"
     CDS             complement(3096..4439)
                     /locus_tag="VQ543_000514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011836724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mur ligase family protein"
                     /protein_id="HET2611294.1"
                     /translation="MNLKTTLGLLAGRSSHFVLSRLGRGSTLPGKVALQFDKDILQSL
                     AKNYEIVVVTGTNGKTLTTALTVGILKEVYGQVLTNPSGANMITGIATTFLTAKSSKT
                     GKNIAVLEIDEASLSRICDYIQPSLFVITNIFRDQMDRFGEIYTTYNMILDAIRKVPT
                     ATVLLNGDSPLFYKPTIPNPIEYFGFDLEKGPAQLAHYNTEGILCPDCQGILKYEHNT
                     YANLGAYICEGCGCKRPDLDYRLTKLVELTNNRSRFVIDGQEYGIQIGGLYNIYNALA
                     AVAIARFLGADSQLIKQGFDKSRAVFGRQETFHIGDKECTLVLIKNPVGATQAIEMIK
                     LAPYPFSLSVLLNANYADGIDTSWIWDADFEQITDMDIPEINAGGVRHSEIARRLRVT
                     GYPAEKITETSNLEQVLKTIENQDCKHAYILATYTAMLEFRELLASRQIVRKEMN"
     gene            complement(4538..5854)
                     /locus_tag="VQ543_000515"
     CDS             complement(4538..5854)
                     /locus_tag="VQ543_000515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000958936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-containing oxidoreductase"
                     /protein_id="HET2611295.1"
                     /translation="MLTYDLIVIGFGKAGKTLAGKLASAGKKVALVERSKAMYGGTCI
                     NIGCIPTKTLLVAAEKDLSFEEVIATKNTITGRLNGKNYATVAGTGVDIFDAEAHFLS
                     NKVIEIQAGDEKKELTAETIVINTGAVSNVLPIPGLATSKNIFDSTGIQSLDKLPEKL
                     GILGGGNIGLEFAGLYNKLGSKVTVLDALDTFLPRAEPSIAALAKQYMEEDGIELLQN
                     IHTTEIKNDGDQVLVVTEDETYRFDALLYATGRKPNVEPLQLENTDIELTERGAIKVD
                     KHCQTNVPGVFAVGDVNGGLQFTYISLDDFRVVYSYLAGDGSYTLEDRLNVPNTMFIT
                     PALSQVGLTESQAADLKLPYAVKEIPVAAMPRGHVNGDLRGAFKAVVNTETKEILGAS
                     IFSEGSQEIINIITVAMDNKIPYTYFTKQIFTHPTLAENLNDLFAI"
     gene            6047..7268
                     /locus_tag="VQ543_000516"
                     /pseudo
     CDS             6047..7268
                     /locus_tag="VQ543_000516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000841575.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="OFA family MFS transporter"
     gene            7467..9041
                     /locus_tag="VQ543_000517"
     CDS             7467..9041
                     /locus_tag="VQ543_000517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HET2611296.1"
                     /translation="MKFNELNLSADLLAEIEKAGFVEASPIQEQTIPLALEGKDVIGQ
                     AQTGTGKTAAFGLPTLEKIRTEEATIQALVIAPTRELAVQSQEELFRFGRSKGVKVRS
                     VYGGSSIEKQIKALKSGAHIVVGTPGRLLDLIKRKALKLQDIETLILDEADEMLNMGF
                     LEDIEAIISRVPENRQTLLFSATMPDAIKRIGVQFMKAPEHVKIAAKELTTELVDQYY
                     IRVKEQEKFDTMTRLMDVAQPELAIVFGRTKRRVDELTRGLKIRGFRAEGIHGDLDQN
                     KRLRVLRDFKNGNLDVLVATDVAARGLDISGVTHVYNYDIPQDPESYVHRIGRTGRAG
                     KSGQSITFVAPNEMGYLQIIENLTKKRMKGLKPASVEESFQSKKQVALKKIERDFADE
                     TIRANFEKFGKDARKLAAEFTPEELAMYILSLTVQDPDSLPEVEIAREKPLPFKPSGN
                     GFGGKAKGGRGGRRGDDRRERDRRGNGRRDEFKKGSRGNDRFDKEKRYRKDNKKPRNT
                     LSEKQTGFVIRNKGDK"
     gene            9305..10093
                     /gene="codY"
                     /locus_tag="VQ543_000518"
     CDS             9305..10093
                     /gene="codY"
                     /locus_tag="VQ543_000518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-sensing pleiotropic transcriptional
                     regulator CodY"
                     /protein_id="HET2611297.1"
                     /translation="MAHLLEKTRKITSILKRSEEQLQDELPYNAITRQLADIIHCNAC
                     IINSKGRLLGYFMRYKTNTDRVEQFFQTKIFPDDYVQGANMIYETEANLPVEHDMSIF
                     PVESRDDFPDGLTTIAPIHVSGIRLGSLIIWRNDKKFEDEDLVLVEIASTVVGIQLLN
                     FQREEDEKNIRRRTAVTMAVNTLSYSELRAVSAILGELNGNEGKLTASVIADRIGITR
                     SVIVNALRKLESAGIIESRSLGMKGTYLKVLISDIFEEVKKRDY"
     gene            10093..10668
                     /locus_tag="VQ543_000519"
     CDS             10093..10668
                     /locus_tag="VQ543_000519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HET2611298.1"
                     /translation="MTKALISIDYTEDFVADSGKLTAGAPAQAISDAISKVTRLAFER
                     GDYIFFTIDAHEENDFFHPESKLFPPHNLIGTSGRNLYGDLGIFYQEHGSDSRVFWMD
                     KRHYSAFSGTDLDIRLRERRVSTVILTGVLTDICVLHTAIDAYNLGYDIEIVKPAVAS
                     IWPENHQFALGHFKNTLGAKLVDENLNELSE"
     gene            10750..10835
                     /locus_tag="VQ543_000520"
     tRNA            10750..10835
                     /locus_tag="VQ543_000520"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:10784..10786,aa:Leu,seq:aag)
     gene            11118..12248
                     /gene="ugpC"
                     /locus_tag="VQ543_000521"
     CDS             11118..12248
                     /gene="ugpC"
                     /locus_tag="VQ543_000521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003010064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sn-glycerol-3-phosphate ABC transporter
                     ATP-binding protein UgpC"
                     /protein_id="HET2611299.1"
                     /translation="MVELNLKNIYKKYPNSEHYSVEDFNLNIKDKEFIVFVGPSGCGK
                     STTLRMIAGLEDITEGTASIDGVVVNDVAPKDRDIAMVFQNYALYPHMTVYDNMAFGL
                     KLRKYSKEDINKRVQEAAEILGLKEFLERKPADLSGGQRQRVAMGRAIVRDAKVFLMD
                     EPLSNLDAKLRVSMRAEIAKIHRRIGATTIYVTHDQTEAMTLADRIVIMSATKNPAGT
                     GTIGRVEQIGTPQEVYKNPVNKFVAGFIGSPAMNFINVKLVGSEIVSDGFRLKVPEGA
                     LKVLREKGYEGKELIFGIRPEDVNAEPAFLETFPDCVVKATISVSELLGSESHLYCQV
                     GKDEFVAKVDARDYLQTGATVELGFDLNKAHFFDVETEKTIY"
     gene            complement(12395..12541)
                     /locus_tag="VQ543_000522"
     CDS             complement(12395..12541)
                     /locus_tag="VQ543_000522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2611300.1"
                     /translation="MEIKEQTRKLAVSCSKYIFEVADKTDEISNHTYGKATLTWFEEI
                     FEEY"
     gene            12749..13507
                     /locus_tag="VQ543_000523"
     CDS             12749..13507
                     /locus_tag="VQ543_000523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001848902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HET2611301.1"
                     /translation="MSEAGHKFLAKLGKKRLRPGGKRATDWLIAEGGLSKEKRILEVA
                     CNRGTTAIELAQRFGCKITAVDMDAQALEVAKKSAGTAGVAHLISFERANAMKLPYQD
                     ASFDIVINEAMLTMQADQAKKKCVMEYLRVLKPGGLLLTHDVLLKEAKESIRQELSQA
                     IHVNVGPLTQDGWEQVMIESGYCDVKVLTGEMTLMKLSGMIYDEGWLGTLKICVNACK
                     KENRKQFLTMYKMFAKNKQKLGFIAMASYKSSKR"
     gene            13594..14106
                     /locus_tag="VQ543_000524"
     CDS             13594..14106
                     /locus_tag="VQ543_000524"
                     /EC_number="2.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001049318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine phosphoribosyltransferase"
                     /protein_id="HET2611302.1"
                     /translation="MNLKDYIATIENYPKEGITFRDISPLMADGNAYSYAVREIVQYA
                     TDKKVDMIVGPEARGFIVGCPVAFELGIGFAPVRKPGKLPREVISADYEKEYGVDTLT
                     MHADAIKPGQRVLIVDDLLATGGTVKATIEMIEKLGGVMAGCAFLVELDELNGREKIG
                     DYDYKVLMHY"
     gene            14288..15232
                     /locus_tag="VQ543_000525"
     CDS             14288..15232
                     /locus_tag="VQ543_000525"
                     /EC_number="2.3.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001122710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine O-succinyltransferase"
                     /protein_id="HET2611303.1"
                     /translation="MPIRIDKKLPAVEILRTENIFVMDDQRAAHQDIRPLKILILNLM
                     PQKMVTETQLLRHLANTPLQLDIDFLYMESHRSKTTRSEHMETFYKTFPEVKDEYFDG
                     MIITGAPVEHLPFEEVDYWEEFRQMLEWSKTHVYSTLHICWGAQAGLYLRYGVEKYQM
                     DSKLSGIYPQDTLKEGHLLFRGFDDSYVSPHSRHTEISKEEVLNKTNLEILSEGPQVG
                     VSILASRDLREIYSFGHLEYDRDTLAKEYFRDRDAGFDPHIPENYFKDDDVNQVPCLC
                     WSSSAALFFSNWVNHAVYQETPFDWRKIEDDASAYGYL"
     gene            15241..15918
                     /locus_tag="VQ543_000526"
     CDS             15241..15918
                     /locus_tag="VQ543_000526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain-containing protein"
                     /protein_id="HET2611304.1"
                     /translation="MTYLDAFKSGTLVLPSALLLHFKELFPSSDDFLVWQFFYLQNTT
                     GLEEMSPSQIAERIGKEISDVNQSISNLTERGLLQYRTIELNGEIELLFDASLALERL
                     DDLFGAVRSSSDQLTPQNQLKDLVETFQQELGRLLTPFEIEDLTKTLKEDGTSADLIK
                     EALREAVLNGKPNWKYIQAILRNWRHEGIKSVAQIEAKRAEREASNPQLTQVSADFRN
                     AMDLWKD"
     gene            16016..16774
                     /locus_tag="VQ543_000527"
     CDS             16016..16774
                     /locus_tag="VQ543_000527"
                     /EC_number="5.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000087908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triose-phosphate isomerase"
                     /protein_id="HET2611305.1"
                     /translation="MSRKPFIAGNWKMNKNPEEAKAFVEAVASKLPSSDLVEAGIAAP
                     ALDLTTVLAVAKGSNLKVAAQNCYFENAGAFTGETSPQVLKEIGTDYVVIGHSERRDY
                     FHETDEDINKKAKAIFANGMLPIICCGESLETYEAGKAAEFVGAQVSAALAGLTAEQV
                     AASVIAYEPIWAIGTGKSASQDDAQKMCKVVRDVVAADFGQEVADKVRVQYGGSVKPE
                     NVASYMACPDVDGALVGGASLEAESFLALLDFVK"
     gene            16812..18317
                     /gene="lytC"
                     /locus_tag="VQ543_000528"
     CDS             16812..18317
                     /gene="lytC"
                     /locus_tag="VQ543_000528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_078138769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline binding-anchored murein hydrolase LytC"
                     /protein_id="HET2611306.1"
                     /translation="MSVTFFIGEERLKTKIGLASICLLGLATSHVAANETEVAKTSQD
                     TTTASSSSEQNQSSNKTQTSTEVQTNAAAHWDGDYYVKDDGSKAQSEWIFDNYYKAWF
                     YINSDGRYSQNEWHGNYYLKSGGYMAQNEWIYDSNYKSWFYLKSDGAYAHQEWQLIGN
                     KWYYFKKWGYMAKSQWQGSYFLNGQGAMMQNEWLYDPAYSAYFYLKSDGTYANQEWQK
                     VGGKWYYFKKWGYMARNEWQGNYYLTGSGAMATDEVIMDGARYIFAASGELKEKKDLN
                     VGWVHRDGKRYFFNNREEQVGTEHAKKIIDISEHNGRINDWKKVIDENEVDGVIVRLG
                     YSGKEDKELAHNIKELNRLGIPYGVYLYTYAENETDAESDAKQTIELIKKYNMNLSYP
                     IYYDVENWEYVNKSKRAPSDTGTWVKIINKYMDTMKQAGYQNVYVYSYRSLLQTRLKH
                     PDILKHVNWVAAYTNALEWENPHYSGKKGWQYTSSEYMKGIQGRVDVSVWY"
     gene            18813..19331
                     /locus_tag="VQ543_000529"
     CDS             18813..19331
                     /locus_tag="VQ543_000529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA starvation/stationary phase protection
                     protein"
                     /protein_id="HET2611307.1"
                     /translation="MVELKKEAVKDVTSLTKAAPVALAKTKEVLNQAVADLYVAHVAL
                     HQVHWYMHGRGFLVWHPKMDEYMEALDGQLDEISERLITLGGSPFSTLTEFLQNSEIE
                     EEAGEYRNVEESLERVLVIYRYLSELFQKGLDVTDEEGDDVTNGIFAGAKTETDKTIW
                     MLAAELGQAPGL"
     gene            19461..19967
                     /locus_tag="VQ543_000530"
     CDS             19461..19967
                     /locus_tag="VQ543_000530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000162460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HET2611308.1"
                     /translation="MTKKIVAIWAQDEEGVIGKENRLPWHLPAELQHFKETTLNHAIL
                     MGRVTFDGMGRRLLPKRETLILTRNPEEKIDGVATFQDVQSVLDWYQAQEKNLYIIGG
                     KQIFQAFEPYLDEVIVTHIHARVEGDTYFPEELDLSLFETVSSKFYAKDEKNPYDFTI
                     QYRKRKEV"
     gene            19967..20137
                     /locus_tag="VQ543_000531"
     CDS             19967..20137
                     /locus_tag="VQ543_000531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000442275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2611309.1"
                     /translation="MERSLFGLFTAFLCFICFLAGAQAFRKKRYGLSILLWLNAFTNL
                     VNSIHAFYMTLF"
     gene            20169..21401
                     /gene="clpX"
                     /locus_tag="VQ543_000532"
     CDS             20169..21401
                     /gene="clpX"
                     /locus_tag="VQ543_000532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002874765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpX"
                     /protein_id="HET2611310.1"
                     /translation="MSTNRKNDMMVYCSFCGKNQEEVQKIIAGNNAFICNECVELAQE
                     IIREELVEEVLADLSEVPKPIELLHILNHYVIGQDRAKRALAVAVYNHYKRINFHDTR
                     EESEDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATALTEAGYVGEDVEN
                     ILLKLLQVADFNIERAERGIIYVDEIDKIAKKSENVSITRDVSGEGVQQALLKIIEGT
                     VASVPPQGGRKHPQQEMIQVDTKNILFIVGGAFDGIEEIVKQRLGEKVIGFGQNNKAI
                     DENSSYMQEIIAEDIQKFGIIPELIGRLPVFAALEQLTVDDLVRILKEPRNALVKQYQ
                     TLLSYDDVELEFDDEALQEIANKAIERKTGARGLRSIIEETMLDVMFEVPSQENVKLV
                     RITKETVDGTDKPILETA"
     gene            21410..21997
                     /locus_tag="VQ543_000533"
     CDS             21410..21997
                     /locus_tag="VQ543_000533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002915299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihA family ribosome biogenesis GTP-binding
                     protein"
                     /protein_id="HET2611311.1"
                     /translation="MELNTHNAEILLSAANKSHYPQDELPEIALAGRSNVGKSSFINT
                     MLNRKNLARTSGKPGKTQLLNFFNIDDKMRFVDVPGYGYARVSKKEREKWGCMIEEYL
                     TTRENLRAVVSLVDLRHDPSADDVQMYEFLKYYEIPVIIVATKADKIPRGKWNKHESA
                     IKKKLNFDPSDDFILFSSVSKAGMDEAWDAILEKL"
     gene            22008..22388
                     /locus_tag="VQ543_000534"
     CDS             22008..22388
                     /locus_tag="VQ543_000534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RidA family protein"
                     /protein_id="HET2611312.1"
                     /translation="MAKTIHTDKAPKAIGPYVQGKIVGNLLFASGQVPLSPETGEIVG
                     ENIQEQTEQVLKNIGAILAEAGTDFDHVVKTTCFLSDMNDFVPFNEVYQTAFKEEFPA
                     RSAVEVARLPRDVKVEIEVIAEIG"
     gene            22440..23330
                     /gene="rapZ"
                     /locus_tag="VQ543_000535"
     CDS             22440..23330
                     /gene="rapZ"
                     /locus_tag="VQ543_000535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNase adapter RapZ"
                     /protein_id="HET2611313.1"
                     /translation="MTKKQLHLVIVTGMSGAGKTVAIQSFEDLGYFTIDNMPPALLPK
                     FLQLVEIKEDNPKLALVVDMRSRSFFSEIQAVLDELENQDGLDFKILFLDAADKELVA
                     RYKETRRSHPLAADGRILDGIKLERELLAPLKNMSQNVVDTTELTPRELRKTLAEQFS
                     DQEQAQSFRIEVMSFGFKYGIPIDADLVFDVRFLPNPYYLPELRNQTGVDEPVYDYVM
                     NHPESEDFYQHLLALIEPILPSYQKEGKSVLTIAMGCTGGQHRSVAFAKRLAQDLSKN
                     WSVNEGHRDKDRRKETVNRS"
     gene            23327..24304
                     /locus_tag="VQ543_000536"
     CDS             23327..24304
                     /locus_tag="VQ543_000536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YvcK family protein"
                     /protein_id="HET2611314.1"
                     /translation="MRKPKITVIGGGTGIPVILKSLREKDVEIAAIVTVADDGGSSGE
                     LRKNMQQLTPPGDLRNVLVAMSDMPKFYEKVFQYRFSEDAGAFAGHPLGNLIIAGLSE
                     MQGSTYNAMQLLSKFFHTTGKIYPSSDHPLTLHAVFQDGTEVAGESHIVDHRGIIDNV
                     YVTNALNDDTPLASRRVVQTILESDMIVLGPGSLFTSILPNIVIKEIGRALLETKAEI
                     AYVCNIMTQRGETEHFTDSDHVEVLHRHLGRPFIDTVLVNIEKVPQEYMNSNRFDEYL
                     VQVEHDFVGLCKQVSRVISSNFLRLENGGAFHDGDLIVDELMRIIQVKK"
     gene            24301..25212
                     /gene="whiA"
                     /locus_tag="VQ543_000537"
     CDS             24301..25212
                     /gene="whiA"
                     /locus_tag="VQ543_000537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein WhiA"
                     /protein_id="HET2611315.1"
                     /translation="MSFTVAVKEEILGQHHLSRHELSAIIKMSGSIGLSTSGLTLSVV
                     TENAKLARHLYESFLHFYEIKSEIRHHQRSNLRKNRVYTVFTDEKVQDLLSDLHLADS
                     FFGLETGIDEAILSDEEAGRAYLCGAFLANGSIRDPESGKYQLEISSVYLDHAQGIAS
                     LLQQFLLDAKVLERKKGAVTYLQRAEDIMDFLIVIGAMQARDDFERVKILRETRNDLN
                     RANNAETANIARTVSASMKTINNISKIKDIMGLENLPVDLQEVAQLRIQHPDYSIQQL
                     ADSLSTPLTKSGVNHRLRKINKIADEL"
     gene            complement(25246..26214)
                     /locus_tag="VQ543_000538"
     CDS             complement(25246..26214)
                     /locus_tag="VQ543_000538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000081018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HET2611316.1"
                     /translation="MSQLYDITIVGGGPVGLFAAFYAHLRQAKVQIIDSLPQLGGQPA
                     ILYPEKEILDVPGFPNLTGEELTNRLIEQLNGFDTPIHLNETVLEIDKQEEEFAITTS
                     KGSHLTKTVIIAMGGGAFKPRPLELEGVEGYENIHYHVSNIQQYAGKKVTILGGGDSA
                     VDWTLAFEKIAPTTLVHRRDNFRALEHSVQALQESSVTIKTPFAPSQLLGNGKTLDKL
                     EITKVKSDETETIDLDHLFVNYGFKSSVGNLKNWGLDLNRHKIIVNSKQESSQAGIYA
                     IGDCCYYDGKIDLIATGLGEAPTAVNNAINYIDPEQKVQPKHSTSL"
     gene            26350..27207
                     /locus_tag="VQ543_000539"
     CDS             26350..27207
                     /locus_tag="VQ543_000539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001867651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00159 family protein"
                     /protein_id="HET2611317.1"
                     /translation="MNFQQLSNLQYWTSLFASPWTIAINLIDILIVAYILYHFTKAIA
                     GTKIMILVRGVLVFILAQILANMIGLTTISWLINQIITYGVIAAVVIFSPEIRTGLER
                     LGRATDFFSNAPISAEEQMIRAFVKSVEYMSPRKIGALVAIQRVRTLQEYISTGIPLD
                     AKISAELLINIFIPNTPLHDGAVIIKEERIAVTSAYLPLTKNTGISKEFGTRHRAAIG
                     LSEVSDALTFVVSEETGGISITYNGRFKHNLTLDEFETELREILLPKEEVGLSFKERL
                     LGGWKHEKK"
     gene            27194..27973
                     /locus_tag="VQ543_000540"
     CDS             27194..27973
                     /locus_tag="VQ543_000540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbbR-like domain-containing protein"
                     /protein_id="HET2611318.1"
                     /translation="MKKNSLYIISSLFFACVLFVYATATNFQNSTSARQVKTETYTNT
                     VTNVPIDIRYNSDKYFISGFASEVSVVLTGANRLSLASEMQESTRKFKVTADLTDAGV
                     GTIEVPLSIEDLPNGLTAVATPQKITVKIGKKAQKDKVKIVPEIDPSQIDSRVQIENV
                     MVSDKEVSITSDQETLDRIDKIIAVLPTSERITGNYSGSVPLQAIDRNGVVLPAVITP
                     FDTIMKVTTKPVAPSSSTSNSSTSSSSETSSSTKATSSKTN"
     gene            27997..29349
                     /locus_tag="VQ543_000541"
     CDS             27997..29349
                     /locus_tag="VQ543_000541"
                     /EC_number="5.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglucosamine mutase"
                     /protein_id="HET2611319.1"
                     /translation="MGKYFGTDGVRGEANLELTPELAFKLGRFGGYVLSQHETEAPKV
                     FVGRDTRISGEMLESALVAGLLSVGIHVYKLGVLATPAVAYLVETEGASAGVMISASH
                     NPALDNGIKFFGGDGFKLDDEKEAEIEALLDAEEDTLPRPSAEGLGILVDYPEGLRKY
                     EGYLVSTGTPLDGMKVALDTANGAASTSARQIFADLGAQLTVIGETPDGLNINLNVGS
                     THPEALQEVVKESGSAIGLAFDGDSDRLIAVDENGDIVDGDKIMYIIGKYLSEKGQLA
                     QNTIVTTVMSNLGFHKALNREGINKAVTAVGDRYVVEEMRKSGYNLGGEQSGHVILMD
                     YNTTGDGQLSAIQLTKIMKETGKSLSELAAEVTIYPQKLVNIRVENVMKEKAMEVPAI
                     KAIIEKMEEEMAGNGRILVRPSGTEPLLRVMAEAPTTEEVDYYVDTITDVVRAEIGID
                     "
     gene            29423..29797
                     /locus_tag="VQ543_000542"
     CDS             29423..29797
                     /locus_tag="VQ543_000542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001050081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1149 family protein"
                     /protein_id="HET2611320.1"
                     /translation="MNLKREQEFVSQYHFDARNFEWENENGAPETKVDVNFQLLQHDQ
                     ENQVTSLIVILSFMIVFDKFVISGTISQVNHIDGRIVNEPSELNQEEVETLARPCLNM
                     LNRLTYEVTEIALDLPGINLEF"
     gene            29799..30647
                     /locus_tag="VQ543_000543"
     CDS             29799..30647
                     /locus_tag="VQ543_000543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HET2611321.1"
                     /translation="MKLAVFTDSSAYLSEETLQREDLFVLDIPVNIDGEEYVEGINLS
                     AEEFYQKMAQASELPKTSQPSIAKLDEILTSLKEQGYTHALGLFLSSGISGFYQNIQY
                     MVDDYEGLTIAFPDTLITSAPLGIMVESVFNWRDQGDDFASIQDKLAIQISRTSAFIM
                     VDDLDHLVKGGRLSNGAAILGNLLSIKPILYFNDQGVIEVYEKVRTEKKATKRLIEII
                     KETTASGQYRVIVIHGNAPEKAEELRQHLLDFGLGSDVSLATFGSVIGTHLGAGSIAL
                     GYIPVI"
     gene            30924..31691
                     /locus_tag="VQ543_000544"
     CDS             30924..31691
                     /locus_tag="VQ543_000544"
                     /EC_number="1.17.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate reductase"
                     /protein_id="HET2611322.1"
                     /translation="MSIRVIIAGFKGKMGQAACQMVLTDPDLDLVAVLDPFESESEWQ
                     GIPVFKDKADLAGFEADVWVDFTTPAVAYENTRFALENGFAPVVGTTGFTSEEIAELK
                     EFSRAQDLGGLIAPNFALGAVLLMQFATQAAKYFPNVEIIELHHDKKKDAPSGTAIKT
                     AELMAEVRESIQQGAADEEELIAGARGADFDDMRIHSVRLPGLVAHQEVIFGNQGEGL
                     TLRHDSYDRISFMTGVNLGIKEVVKRHELVYGLEHLL"
     gene            31703..32887
                     /locus_tag="VQ543_000545"
     CDS             31703..32887
                     /locus_tag="VQ543_000545"
                     /EC_number="2.7.7.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001138849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CCA tRNA nucleotidyltransferase"
                     /protein_id="HET2611323.1"
                     /translation="MPSEFQKALPVLEKIKEAGFEAYFVGGSVRDALLHSPIHDVDIA
                     TSSYPEETKQIFPRTADIGIEHGTVLVLDGDEEYEVTTFRTEDVYVDYRRPSAVSFVR
                     SLEEDLKRRDFTVNAFALDETGEIVDLFHGLEDLEKQVLRAVGVASERFNEDALRIMR
                     GFRFQASLGFALEPETFKAMKTLTPLLEKISVERTFVEFDKLLLAPFWRRGLASMIES
                     QAYDYLPDMASSQDKLNRLFDLETDFTFESSEQAWAALLWALEIENAQSFLKSWKTSR
                     QFAKQVQDLLIILALRENGELSKRDCYRFDIDLLLQAENLRQAQGKEVNPQAITEKYQ
                     SLTIHDKKEIQINGDILIKEYGYQPGPDLGEILTEIEFAIVDGELENNREAIHAYLRE
                     KK"
     gene            32884..34755
                     /locus_tag="VQ543_000546"
     CDS             32884..34755
                     /locus_tag="VQ543_000546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001279112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HET2611324.1"
                     /translation="MSDFIVEKLSKSVGDKTVFRDISFIIHDLDRIGLIGVNGTGKTT
                     LLDVLSGVSGFDGDVSPFSAKNDYQIGYLTQDPDFDDRKTVLDTVLSSELKEIQLIRE
                     YELIMLDYSEDKQARLERVMAEMDSLQAWEIESQVKTVLSKLGIQDLSTPVGELSGGL
                     RRRVQLAQVLLGNHDLLLLDEPTNHLDIAIIEWLTLFLKNSKKTVLFITHDRYFLDAL
                     STRIFELDRAGLTEYQGNYQDYVRLKAEQDERDAALLHKKEQLYKQELAWMRRQPQAR
                     ATKQQARINRFHDLKKEVSGSSAETDLTMNFETSRIGKKVIEFQAVSFAYENKPILQD
                     FNLLVQAKDRIGIVGDNGVGKSTLLNLIAGSLEPTKGQVVIGETVRIAYFSQQIEGLD
                     ESKRVINYLQEVAEEVKTSGGSTTSIAELLEQFLFPRSTHGTLIEKLSGGEKKRLYLL
                     KLLLEKPNVLLLDEPTNDLDIATLTVLENFLQGFAGPVLTVSHDRYFLDKVATKILAF
                     EDSKIRPFFGHYTDYLDEKAFETDMANQVQKVEKEKVVKVREDKKRMTYQEKQEWASI
                     EGDIETLEKRIAAIEEEMQANGSDFGKLATLQKELDEKNEALLEKYERYEYLSEFDS"
     gene            complement(34898..36082)
                     /gene="mntE"
                     /locus_tag="VQ543_000547"
     CDS             complement(34898..36082)
                     /gene="mntE"
                     /locus_tag="VQ543_000547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000813920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDF family manganese efflux transporter MntE"
                     /protein_id="HET2611325.1"
                     /translation="MKQSISNLKLAERGAIISISTYLILSAAKLAAGHLLHSSSLVAD
                     GFNNVSDIIGNVALLIGIRMARQPADRDHRFGHWKIEDLASLITSIIMFYVGFDVLRD
                     TIQKILSREETVIDPLGATLGIISAAIMFVVYLYNTRLSKKSNSKALKAAAKDNLSDA
                     VTSLGTAIAILASSFNYPIVDKLVAIIITFFILKTAYDIFIESSFSLSDGFDDRLLED
                     YQKAIMEIPKISKVKSQRGRTYGSNIYLDITLEMNPDLSVFESHEIADQVESMLEERF
                     GVFDTDVHIEPAPISEDEILDNVYKKLLMREQLIDQGNQLEELLTDDFVYIRQDGEQM
                     DKEAYKTKKELNSAIKDIQITSISQKTKLICYELDGIIHTSIWRRHETWQNIFHQETK
                     KE"
     gene            36386..39082
                     /locus_tag="VQ543_000548"
     CDS             36386..39082
                     /locus_tag="VQ543_000548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HET2611326.1"
                     /translation="MSKEQKRQAFYTQSPEEVLQAVDATEQGLSSSEAEKRLAEFGHN
                     ELEEGEKRSILVKFIEQFKDLMIIILVAAAILSVVTSGGEDIADAIIILAVVIINAAF
                     GVYQEGKAEEAIEALKSMSSPVARVLRDGHMAEIDSKELVPGDIVALEAGDVVPADLR
                     LIEANSLKIEEAALTGESVPVEKDLSVELATDAGIGDRVNMAFQNSNVTYGRGMGVVV
                     NTGMYTEVGHIAGMLQDADETDTPLKQNLNNLSKVLTYAILVIALVTFVVGVFIQGKN
                     PLGELLTSVALAVAAIPEGLPAIVTIVLSLGTQVLAKRHSIVRKLPAVETLGSTEIIA
                     SDKTGTLTMNKMTVEKVFYDAVLHDSADDIELGLEMPLLRSVVLANDTKIDVEGNLIG
                     DPTETAFIQYALDKGYDVKGFLEKYPRVAELPFDSDRKLMSTVHPLPDGRFLVAVKGA
                     PDQLLKRCLLRDKAGDIAPIDEKVTNLIHTNNSEMAHQALRVLAGAYKIIDSIPENLT
                     SEELENDLIFTGLIGMIDPERPEAAEAVRVAKEAGIRPIMITGDHQDTAEAIAKRLGI
                     IDANDTEGHVLTGAELNELSDEEFEKVVGQYSVYARVSPEHKVRIVKAWQKQGKVVAM
                     TGDGVNDAPALKTADIGIGMGITGTEVSKGASDMILADDNFATIIVAVEEGRKVFSNI
                     QKTIQYLLSANTAEVLTIFLSTLFGWDVLQPVHLLWINLVTDTFPAIALGVEPAEPGV
                     MNHKPRGRKASFFSGGVLSSIIYQGVLQAALVMSVYGLAIAYPVHVGDNHAIHADALT
                     MAFATLGLIQLFHAYNVKSVYQSILTVGPFKSKTFNWSILVSFILLMATIVVEPLEGI
                     FHVTKLDLSQWGIVMAGSFSMIIIVEIVKFIQRKLGFDKNAI"
     gene            39095..39886
                     /gene="yghU"
                     /locus_tag="VQ543_000549"
     CDS             39095..39886
                     /gene="yghU"
                     /locus_tag="VQ543_000549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001277405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-dependent disulfide-bond
                     oxidoreductase"
                     /protein_id="HET2611327.1"
                     /translation="MSAYQLPTVWQDEASNQGAFTGLNRPTAGARFEQNLPKGEQAFQ
                     LYSLGTPNGVKVTILLEELLEAGFKEAAYDLYKIAIMDGDQFGSDFVKLNPNSKIPAL
                     LDQSGTENVRVFESAHILLYLAEKFGAFLPSNPVEKVEVLNWLFWQAGAAPFLGGGFG
                     HFFNYAPEKLEYPINRFTMEVKRQLDLLDKELAQKPYIAGNDYTIADIAIWSWYGQLV
                     QGNLYQGSAKFLDASSYQNLVKWAEKIANRPAVKRGLEVTYTEIK"
     gene            40002..40412
                     /locus_tag="VQ543_000550"
     CDS             40002..40412
                     /locus_tag="VQ543_000550"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000412213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HET2611328.1"
                     /translation="MEKKIVKDILFLSQVSHPASQEDLYLARDLQDTLLANRDTCVGL
                     AANMIGMQKRVIIFNLGLVPVVMFNPVLLSFEGSYEAEEGCLSLVGVRSTKRYETIRL
                     AYRDSKWQEQTITLTGFPAQICQHELDHLEGRII"
     gene            40424..42019
                     /locus_tag="VQ543_000551"
     CDS             40424..42019
                     /locus_tag="VQ543_000551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000822862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2611329.1"
                     /translation="MKRIVFELIFIATTWYIFLPPLNLTSWEFLFFLCGHLLVVAILF
                     GFGKGINLVKTVHVRHGKAEAALNLEGFKINRLGKILLASIGGILLLAALVSLVTSSM
                     FQAKNYANVVTVTEKDFTEFPKSDTSKVPILDRSTAEKIGDRYLGSLTDKVSQYVAAD
                     TYTQLTIDGKPYRVTPLEYADPIKWFNNQAKGIGEYIKVDMVTGNADLVDLKTPIKYS
                     DSEYFNRDVKRHLRLKYPTKIFKTPSFEVDDEGNPFYVATVYQKQFGLAVPRPASVII
                     LDATNGETKEYSLSDVPEWVDRIYPAEETIEQINYNGKYKDGFLNAMISKKNVTQTTN
                     GYNYLSIGNDIYLYTGVTSANADESNLGFILENMRTGEITKYSLASATEESARESAEG
                     AVQEKSYKATFPILINLNDKPLYIMGLKDNAGLVKEYALVDAVEYQNVIVATTVEEML
                     SKYANKNDLEIDNATTESIKGVVADLKSAVIKGDTVYFFKVDGKIYKVKASVSDDLPY
                     LENGKTFEGQVGKDNYLKTFKVQ"
     gene            42186..42350
                     /locus_tag="VQ543_000552"
     CDS             42186..42350
                     /locus_tag="VQ543_000552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000508323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YczI family protein"
                     /protein_id="HET2611330.1"
                     /translation="MGFYLMVASMLLGLLALKIGFSQFKEKKDKFLSILTSLAGTALV
                     LVAVWLGWPK"
     gene            42429..43157
                     /gene="yaaA"
                     /locus_tag="VQ543_000553"
     CDS             42429..43157
                     /gene="yaaA"
                     /locus_tag="VQ543_000553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxide stress protein YaaA"
                     /protein_id="HET2611331.1"
                     /translation="MKILIPTAKEMNTDLPSIEAIPLKPESQTVLDALALYSASQLES
                     FYKVSAEKAAEEFQNIQALKRQTAQHYPALKLFDGLMYRNIKRDKLTEAEQDYLENHV
                     FITSALYGVVPALSPMAPHRLDFLMKLKVAGKTLKSHWKAVYDEALKKEEVIFSLLSS
                     EFETVFSKEIRAKMVTFKFMEDRGGQLKIHSTISKKARGAFLTALIENQVQTVGEARR
                     LNFAGFVYREDLSQPQGLVFVKEV"
     gene            complement(43208..44692)
                     /locus_tag="VQ543_000554"
     CDS             complement(43208..44692)
                     /locus_tag="VQ543_000554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003096885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HET2611332.1"
                     /translation="MRNLLSTKVQRQLRLMETLIQNRNWMKLHELAEKLGCTERILKS
                     DLNELRIAFPSINIQSSVNGIMIDLEVNTSVEDIYQYFLANSQSFQLLEYMFFNEGLP
                     IYRTIENLYFSSANLYRLGRNITKVLSSQFQIELSFTPSEIRGNEIDIRYFFAQYFSE
                     RYYFLDWPFPDLPEEDLTEFADFFYKITNYPMRFSIYRMYKLMIAISIHRVKNGHFID
                     LPNHFYKEYYPLLKSIPNFQETLAYFSKHFGLEMTPDTIAQIFISFLQNDIFLDPQEF
                     FNSLEDNSQARYSYQLLSQILERLSKQYKITFTNHDELIWHLHNTAFFERQEIFSTPI
                     LFEQKALTIKKFEGYFPDFMGSARQELAQYRQAIGQHDHPEQLEHLMYTILTHAENLS
                     TQLLENRPPIKVLIISNFDHAISLTFVDMLSYYCNNRFTFDIWDELKTSPEILNQTDY
                     DIIVSNFYISGITKKFICRNHLSIMNLVNHLNTLSNEIHLSNTL"
     gene            44908..>46866
                     /locus_tag="VQ543_000555"
     CDS             44908..>46866
                     /locus_tag="VQ543_000555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001816486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HET2611333.1"
                     /translation="MKHSHKKSFDWYSMQQRYSIRKYYFGAVSVLLGTALVLGAAASV
                     QTVQAEENKQETTNSISVGRGEAATKPAEVSASNKEKTYAAPTVANPVETTPVKTGEV
                     TKPAEKVEEAKDKKEEVTHQDAIDKSKLLTALSRAKKLESKLYTEASAANLQTSIQAG
                     QSLLGKADASEAELSAAESSIQSSIIGLELRSNSNKGTVSETPVAKKANIVEAKEETN
                     PAATTDRSAVDSAVLPTSTAAKVETTSAPASINEILKPGLSLSDARQNPAIRKEDVDR
                     GYSGFRAAPAPTNQPVTNLGNNTVFTDISRGSHTFRGNGNSRRGNPIHFDVTTTRVRN
                     RVDFSIRYSGPGEFVNNNFILDKGNGFGEPSRATVSTPKLRDQVKNISKGGNFVSHSG
                     YSLEAAVETSTNQTIKFSLPIANPNGDLSVRLRPVTFNVGQGESGSATSNDPYSNSNY
                     YFREKPLLLDANPNGGTNNKTVSEDIDFQTVYLPTSKLPEGQTRLVREGEKGQRQIIY
                     KVHQLGNETILGLPISNSVIKEVKPRIMQIGVAKDLIDTVKPRVDQNKVGDTNNLTFY
                     LDNDGNGVYTEGVDELVQKIAIKDGAKGEKGDRGERGLTGAQGAKGEKGDRGERGLTG
                     AQGAKGEKGDRGERGLTGAQGAKGEKGDR"
BASE COUNT        14009 a         8671 c        10583 g        13603 t
ORIGIN      
        1 gacctactac tatcacttga aacagctaga caaaacagat aaggaccaag agcttaaagc
       61 tgaaattcaa tccatcttta tcgaacacaa gggaaattat ggttatcgtc gaatttattt
      121 agaactaaga aatcgtggtt atctggtaaa tcataaaaga gttcaaggct tgatgaaagt
      181 actcaattta caagctaaaa tgcgacagaa acgaaaatat tcttctcata aaggagacgt
      241 tggtaagaaa gcagagaatc tcattcaagg ccaatttgaa ggctctaaaa caatggaaaa
      301 gtgctacaca gatgtgacag aatttgccat tccagcaagt actcaaaagc tttacttatc
      361 accagtttta gatggcttta acagtgaaat tatcgcctat aatctttcaa tttcacccaa
      421 cttagaacaa gtacaaacaa tgttggaaca agccttcaca gagaagcact acgagaatac
      481 gattctccat agtgaccaag gctggcaata tcaacacgat tcttatcatc agtttcttga
      541 gggtaaggga attcaagcat ctatgtcacg caagggaaac agccaagaca acggtatgat
      601 ggaatctttc tttgggattc tgaaatcgga aatgttttac ggttatgaga agtcgtttca
      661 gtcgcttaat caattggaac aagctattgt agactatatt gattactaca acaataaacg
      721 aattaaggta aaactaaaag gacttagtcc tgtgcaatac agaactaaat ccttcggata
      781 aattaattgt ctaactgttt gggggcagta catattcaac acctgatact atgcgtttta
      841 ttgtgggaag attttcctca ttttctagtg aaattgaact ttttctaaca tcttttgata
      901 gatgacttct taatcaatta tcatttccat tgttgtttct tggggtttca tcccttgtct
      961 ttgataaaag cggagagcac cctcgttatc attccagaca cttagggtta gattattgca
     1021 gccaatttct ttagcataat agcagaaaaa tgacaataaa atagccccta gatattttga
     1081 aaggaaagca taggggctat atagtttaat caaaataaag caaatctttg ctggtgcttg
     1141 taaagaggtc gaagccatcc ttggtaacaa caccgcagtc ttcaatacga acaccgactt
     1201 taccagggat atagatacct ggttcaacag agaagcacat gccttcttcg atgaccatgt
     1261 cgtttccttc catgatagat gggaattcat ggacatccat accgatacca tgcccgagac
     1321 ggtggttgaa gtactcacca taaccagctt tttcgatgac ctcacgggca gcgcggtcca
     1381 cttcatgagc agtcacacct ggcttgataa agtcaagagc agcttgttgg gcttcaagag
     1441 tcaagttgta aatatctttc ttgaattggt ctggtttgcc gacagcgact gtacgagtca
     1501 tatctgacgc atagccattg accagaacac ccaggtcaaa gaggagaaga gcatcatttt
     1561 caaccttatt agctgctgga atgccgtgtg gattcgcagc attatcacca gtcaagacca
     1621 tggtatcaaa gctcatttca taaccttcac gtttcatggc aaagtcgatt tgtgcgatga
     1681 tatctgtctc agtcttatca agagaaatat tgtcaaaacc aacatgaaca gccttgtcag
     1741 cataaagacc tgcaaccatc attttttgca cttcatcagc tgatttgatg aggcgcatgc
     1801 gttggatacg aggagtgagg ttgtcaaact cagcagtctc aaaaactgtt ttcaaaccat
     1861 ggtatttggt caagatgaga ttgtcaaact caacagcgac acgtttgaag tcaagttgtg
     1921 gaagagcatg tttgattttt tgccatggat tttcagaatc gacatagccc actactggga
     1981 aggaaacggt gctacttgca cgttctactt caagagctgg gacaaagagg agaggttcct
     2041 gatccgctag gacaaagagg aacatttggc gttcatgggg atcactgtaa aaaccagtga
     2101 ggtaattgat tgtgacgggg tcagatacga cagcgacgtc tagtttttct gattcaagat
     2161 atgttaggat ttgttgtaat ttagacatat gctaccttct ttctacccct ctattttggc
     2221 aaaaaatgag agaaaatgca agggagaagg gtaaaagaaa agacaaaaaa ctccgacaag
     2281 ataacggagt tctttgatat cattttcctt tgtttaagaa aagtcagcct tgcttttgac
     2341 gtcactgtac tcttcagcga tttcttggct gagaatgtcc tcataggcag ggagttggat
     2401 gtcctgacca tatttcttct tgagggcagt agtaactagg cgataagcca gattggcatt
     2461 acgagagagg ataggcccgt ggaagtagga accaaagaca ttcttataat gaaccccttc
     2521 accgaccttt tcttcgttgt ttccatttcc atagacaacc tgtcccagcg gtttttggtc
     2581 atcagagagg aaggtacgac cttggtgatt ttcaaatcca tagtaggttt catcgaaatc
     2641 ttcattgtga atcttgatgt caccgataaa acggttattg gtctggttga gcgtgtagtg
     2701 tcccatgacc cctagccctt cgatacgttt tcctgaagct tcaacataat attgacccaa
     2761 tagttggaaa ccaccgcaga tagccagaac tacaccgtcg ttttggatgt agttgtcaat
     2821 gctctctttt ttagcaggta ggtcgtctgc aatgatactt tgttcaaagt cttgaccacc
     2881 accgaaaaag gcgatgtcgt agtgattttc atcaaagtca tcatggagag aaacgatgtc
     2941 aacggtcaca tgggctccca gtttttcagc cacatacttg agcatgagga tgtttccatt
     3001 gtccccgtag gtattcatga gatttccgta gaggtgggca atgttgagct gataggggta
     3061 attgctatct tttgaggaaa gtgaagtata aaccattagt tcatctcctt tctaacaatc
     3121 tgacgactag ccagcagttc acgaaattcc agcatggcag tataagttgc cagaatatag
     3181 gcatgcttgc agtcttgatt ctcaatggtc ttgagaactt gctccagatt actcgtttca
     3241 gtgattttct cagctggata gccagtcact cggaggcgac gagcgatttc agaatgacga
     3301 acaccgccag cgttgatttc aggaatgtcc atgtcagtga tttgctcaaa gtctgcatcc
     3361 cagatccagc tagtgtcaat tccatctgca tagttggcat taaggaggac agataggcta
     3421 aatggataag gtgctagttt gatcatttcg atagcttggg ttgcaccgac tggattttta
     3481 atcaagacaa gggtacattc cttgtcaccg atatgaaagg tttcttggcg tccaaagaca
     3541 gcacggctct tgtcaaatcc ctgtttgatg agttgggaat ctgcgccgag gaaacgggcg
     3601 atggccacag cagctagggc gttatagata ttatagagcc cgccgatttg gataccgtat
     3661 tcttggccgt ctatgacaaa gcgagagcga ttgttggtca actcaaccag ttttgtcaaa
     3721 cgatagtcga gatcaggacg tttacatcca caaccttcac agatataggc acccaagttt
     3781 gcataggtat tatgctcata tttgaggatg ccttggcagt caggacagag aatcccttcg
     3841 gtattgtagt gagccagttg ggctggtcct ttttccaagt caaaaccaaa atactctata
     3901 gggtttggaa tagttggctt gtagaaaagt ggactgtctc cgttaaggag aacagtagca
     3961 gttggaactt ttcgaatggc atccaatatc atgttatagg tagtatagat ttcaccgaaa
     4021 cggtccatct ggtcacggaa gatattagta atgacaaaaa gactaggctg gatatagtca
     4081 cagatacgag atagactggc ttcgtcaatt tcgaggacgg caatattttt cccagttttt
     4141 gaagatttgg ctgttaggaa ggttgttgca atccctgtaa tcatgttggc accgcttggg
     4201 ttggttagaa cttgaccata aacctctttt aaaatgccga cagtgagggc agttgtcagg
     4261 gtttttccat ttgttccagt gacaacgaca atctcgtagt tcttagctag gctttgtaaa
     4321 atatctttat caaattgaag ggcgactttc cctgggagcg tacttccacg tccaagacgg
     4381 cttaaaacga agtgggaaga acgcccagca agaaggccca aagtagtttt taagttcatg
     4441 tttctattat atcacaaaag agggaaaaga cagatttggt gtttcgtaga agtaaaaaca
     4501 gcccaaagag ggctgtcagt taagatgaga tttcaactta aatcgcaaac aagtcattca
     4561 agttctcagc caaggttggg tgagtgaaga tttgttttgt gaagtaagtg taaggaatct
     4621 tgttgtccat agcaacagta atgatgttga tgatttcttg agaaccttct gagaagatgc
     4681 ttgcaccaag aatttctttt gtttcagtat taacaacagc tttgaaagct ccgcgaaggt
     4741 ctccatttac gtgaccacga ggcatggctg caacagggat ttctttcact gcgtatggaa
     4801 gtttcaaatc agctgcttgg ctttcagtca aaccaacttg tgaaagtgca ggtgtgatga
     4861 acatagtatt tggcacattg agacggtcct caagtgtgta gctgccatct ccagcaaggt
     4921 agctgtaaac aacacggaag tcatcaagtg aaatgtaagt aaattgaagg ccaccgttga
     4981 catctccaac tgcaaagaca ccaggaacgt ttgtttgaca gtgtttgtct actttaatag
     5041 caccacgttc agttagttca atatctgtat tttcaagttg aagtggttct acatttggtt
     5101 tgcgtccagt tgcgtagaga agggcgtcga aacggtaagt ttcgtcttca gttacgacaa
     5161 gcacttggtc accatcgttt ttgatttcag tagtatggat attttgaagc aattcaatgc
     5221 catcttcttc catgtattgt ttagcaagag ctgcgatgga aggttctgca cgaggtagga
     5281 atgtatccaa ggcatctagg actgtgacct tgcttccaag tttgttgtaa aggccggcaa
     5341 attcaagacc gatatttccg ccaccaagga ttccaagttt ttcaggtaat ttgtccaagc
     5401 tttggatacc tgttgagtca aagatgtttt tgcttgtagc aagtccagga attggcaaga
     5461 cgtttgaaac agcaccagtg ttgatgacga ttgtttcagc agtcagttct ttcttttcat
     5521 caccagcttg gatttcgatg actttatttg aaaggaagtg agcttccgca tcaaagatat
     5581 ctacgcctgt accagcaaca gtcgcatagt ttttaccgtt gaggcgacca gtgatcgtgt
     5641 ttttagtagc aatcacttct tcaaaagaca agtccttttc agcagcaact agcaaggttt
     5701 tagttgggat acaaccaatg ttgatacaag ttccaccgta catagccttg ctgcgttcaa
     5761 cgagggcaac ttttttgcca gctgaagcca atttacctgc tagtgtttta ccagctttac
     5821 caaatccaat aacaattaaa tcgtatgtta acatttatct tcctcctatt cgaatttcat
     5881 tctagcacaa gaaaaaaact tttgcacaat tctgctacgg aaaagacaga aaaagataaa
     5941 aacgctttcc agacaaaaaa ctagtaattt tttgacaagc ttgataaact aaaatcctat
     6001 ctatttttat ataagaaaga ataaatgttc gaaaatagga ggttttatga aatcgaatcg
     6061 ttatattatt gcctttgctg gggtcatttt acacttaatg ctgggttcga cttatgcttg
     6121 gagtgtttat cgtaacccta ttattgaaaa aacgggatgg gatcaggctt ctgttgcctt
     6181 cgcctttagt ctagcaatct tttgtttggg cttatcggct gcatttatgg ggcgtttggt
     6241 agaaaaattt ggtccgaaag tcatggggag tctatctgct tttctatacg caggtggaaa
     6301 tatcttaaca ggatttgcaa tagaccgtca ggaactgtgg ttgttgtatc tagcttatgg
     6361 cattttaggt gggcttggtt tgggagcagg ctatattacc cctgtgtcaa cgattataaa
     6421 atggtttcct gataaacgtg gtctcgcaac aggtttagcg attatggggt ttggttttgc
     6481 ttctttattg actagtccca tagcgcaaca cctcatcgca ggggtaggga ttgtagaaac
     6541 tttttatatt ttaggagcaa gttactttat tatcatgctc ctagcttcac aattcattaa
     6601 gcgtccaaat gagcaagagc ttgcaatttt atcttcttca gggaaagaaa aaacagcctc
     6661 tttgacgcaa ggaatggctg caaatcaggc tctaaaaagc aatcggtttt atatgctttg
     6721 gattattttc tttatcaaca tagcttgtgg tttaggctta atttcagcgg catcgccaat
     6781 ggcacaggag atggctggct tgtctacaag tcatgcagca gtaatggtgg gtgttttggg
     6841 gattttcaat ggatttggtc gcttgctctg ggcgagtttg tctgactata tcggtcgccc
     6901 tctaaccttt agtatattac tgcttgtcaa tcttttctct ctcactttgg ctctttacag
     6961 attccgtttt atttgtagtt gctatgtcta ttttgatgac ttgctatgga gctggttttt
     7021 ctttgattcc agcttatctc agtgatattt ttggaaccaa ggaattggcc gctctgcatg
     7081 gttatatttt aacagcttgg gcaatggctg gtttagcggg acctatttta ttagcagaga
     7141 cttataaaat ggctcattcg tacacacaaa ccttgttcgt ttttctcatt ttatacagta
     7201 tcgccttggc tttgtcttat tatctaggtc gttcaatcaa aaaagaaagt caaaaaccgc
     7261 ttacatgatt ttctgtagaa atggggctat cttttgctct ggtcttgtgt tatactagat
     7321 aggttgcaaa gaaaacagta cttttctttt gtggaaaaga agcaacacga ttttatatct
     7381 agttatatga aaatacgtca taaaaagaaa agtataaact aagccctata gggtggcttc
     7441 gcaccacctt tagaaagaag aataacgtga aatttaatga attaaacttg tctgctgatt
     7501 tgctagcaga aattgaaaaa gctggttttg tagaagctag tcctatccaa gaacaaacta
     7561 ttcctttggc ccttgaaggc aaggatgtta tcggtcaagc tcagactggt acaggaaaaa
     7621 ctgcagcctt tggcttgcct acccttgaaa aaatccgtac agaagaagcg actatccaag
     7681 ctttggtcat cgctccaact cgtgaactag ctgtccaaag tcaagaagaa ctcttccgct
     7741 ttggtcgtag taagggagtc aaagtccgtt cagtatatgg cggatcaagc attgaaaaac
     7801 aaattaaggc tcttaaatct ggtgcccata tcgtggtggg aactccaggt cgcctcttgg
     7861 acttgattaa acgcaaggcc ttgaaattac aagacattga aacccttatc cttgacgaag
     7921 cggatgaaat gcttaacatg ggcttccttg aagacatcga agccattatt tcccgtgtac
     7981 ctgagaaccg tcaaactttg cttttctcag caactatgcc agatgccatc aaacgtatcg
     8041 gtgttcagtt tatgaaagcc cctgaacatg tcaagattgc ggctaaggaa ttgacaacag
     8101 aattggttga ccagtactat atccgtgtta aggaacaaga aaaatttgac accatgactc
     8161 gtctcatgga tgtggcacaa ccagaactcg ctattgtatt tggtcgtacc aaacgccgtg
     8221 tggatgaatt gactcgtggt ttgaaaattc gtggcttccg tgcagaagga attcatggcg
     8281 acctagacca aaacaaacgt cttcgtgtcc ttcgtgactt taaaaatggc aatcttgatg
     8341 ttttggttgc gacagacgtt gcagcgcgtg gtttggatat ttcaggtgtg acccatgtct
     8401 acaactacga tattccacaa gatcctgaga gttatgttca ccgtatcggt cgtacaggtc
     8461 gtgctggtaa gtcaggtcaa tctattactt ttgttgctcc aaacgaaatg ggttaccttc
     8521 aaatcattga aaacttgact aagaaacgca tgaaaggtct caaacctgca agtgtagaag
     8581 aatccttcca atcaaaaaaa caggtagctc tcaagaaaat cgaacgtgat tttgcagatg
     8641 aaaccattcg tgccaacttt gagaaatttg gtaaggatgc tcgcaaattg gctgctgagt
     8701 ttactccaga agaattggca atgtatatct tgagtctgac agtccaagac ccagatagcc
     8761 ttccagaagt ggagattgca cgtgaaaaac cactaccgtt taaaccatca ggtaatggtt
     8821 tcggtggtaa agctaaggga ggtcgtggag gccgtcgtgg ggacgaccgt cgagagcgtg
     8881 atcgccgtgg caatggtcgc cgtgatgagt tcaaaaaagg aagtcgtggc aacgatcgtt
     8941 ttgataagga aaaacgttac cgtaaggata ataaaaaacc acgcaatact ttaagcgaaa
     9001 agcaaacagg ctttgttatt cgtaacaaag gcgataaata agaaaaagcg gttcaaaatg
     9061 aatcgctttt ttatataagg agaccgaatg tgaaaagaca aataaaatta ctatattatc
     9121 ttttataatg ttatgataca caaaaatagg caacttgtca atagaaaagg aacaatttaa
     9181 ttaaaaatat tctggttttt aattaaattg taagtcaatg caagtcaata aggaattttc
     9241 agataattat tgaaaaagag acgtttttat gttataatga tagcgattaa attcgaggtg
     9301 aaaaatggca catttattag aaaaaactag aaaaattaca tcaattttga aacgctcaga
     9361 ggagcagttg caggatgagc tcccttacaa cgctattacg cgtcagttag cggatattat
     9421 tcattgcaat gcctgcatta tcaatagtaa gggacgtctg cttggctatt ttatgcgtta
     9481 taaaacaaat acagatcgcg tagagcaatt cttccaaact aagattttcc cagatgacta
     9541 cgttcaaggg gctaatatga tttacgaaac agaagcaaac ttgcctgttg agcatgatat
     9601 gagtattttc cctgttgaga gtagagatga ttttccagat ggcttgacga ctattgcacc
     9661 gattcatgta tcggggattc gccttggttc tttgattatt tggcgtaatg ataaaaaatt
     9721 cgaagatgag gacttggttc ttgttgagat tgccagtacc gttgttggga ttcagcttct
     9781 taacttccaa cgtgaagaag atgagaaaaa tattcgtcgt cgtactgctg tcaccatggc
     9841 ggtcaatacc ctttcttact ccgaactccg tgctgtttca gcaattttag gggaattaaa
     9901 tggaaatgaa gggaagttga ctgcgtcagt gattgcagat cgtatcggaa tcactcgctc
     9961 tgtgattgtc aatgctcttc gtaaacttga gtctgcgggg attattgaaa gtcgctcact
    10021 tggaatgaag ggaacctatc ttaaggtctt gatttcagat atttttgaag aagtgaagaa
    10081 aagagattac taatgacaaa ggctttaatt tcgattgatt atacagaaga ttttgttgct
    10141 gatagtggga agctgacagc aggtgctcca gctcaggcga tttcggatgc catcagcaag
    10201 gtaactcgat tagcttttga acgaggagat tatatcttct ttactattga tgctcatgaa
    10261 gaaaacgatt ttttccatcc ggaaagtaag ttatttcctc ctcataatct gattgggacg
    10321 agtggacgga atttatatgg agatttgggg atcttttatc aagagcatgg ttcagacagt
    10381 cgtgtctttt ggatggataa acgccattac tcagcttttt cagggactga cctagatatt
    10441 cgtttgagag agcgtagagt gtctaccgtt atcttaacag gtgtcttgac ggatatctgt
    10501 gtcctacata cagctataga tgcctataat ctaggatatg acatcgagat tgttaaacca
    10561 gctgttgctt ccatctggcc tgaaaatcat caatttgccc taggtcattt caaaaataca
    10621 ctcggagcta agttagtaga tgaaaatcta aatgaacttt ctgagtaacc tggttggtga
    10681 aaatgaaaaa atttgaaaaa aagtgttgac aagcatccca aaagttgata tactagtaaa
    10741 gtaatcgatg cggggatggc ggaattggca gacgcgcagg actaaggatc ctgtgaccgc
    10801 tttaggtcgt gagggttcaa gtccctctct ccgcatagga aaagagttag ctaaagctag
    10861 ctcttttgta tttctctaaa aaattagaat ccagtcaaat gtagtggaga atcagcgaaa
    10921 atatgggaaa actgttcctt gtttctgctt ttgtcataga agaataataa agattatctt
    10981 cttcaaattc tccgatattc tctaaagttt tgtgcaagtt gcacagaact tttttatttt
    11041 tttggtcatc ttgccataga aatataaagc gttttcatct ataatataat tatcaaaaga
    11101 caaaaggagt tcacctcatg gtagaattga atcttaaaaa tatttacaaa aaatatccaa
    11161 acagcgaaca ctattcagtt gaagatttca acttgaacat caaagataaa gaatttatcg
    11221 ttttcgtagg accttcagga tgtggtaaat caactacact ccgtatgatt gctggtcttg
    11281 aagacattac agaaggtact gcatctatcg atggcgtggt tgtcaacgac gtagctccaa
    11341 aagaccgtga tatcgccatg gtattccaaa actacgctct ttacccacac atgactgttt
    11401 atgacaacat ggctttcggt ttgaaattgc gtaaatacag caaagaagac attaacaaac
    11461 gtgttcaaga agcagctgaa atacttggat tgaaagaatt cttggaacgt aaaccagctg
    11521 acctttcagg tggtcaacgt caacgtgttg ccatggggcg tgcgattgtc cgtgatgcga
    11581 aagtattctt gatggacgaa cctttgtcaa acttggatgc caaacttcgt gtatcaatgc
    11641 gtgctgaaat cgctaaaatt caccgtcgta tcggagctac aactatctat gtaactcacg
    11701 accaaacaga agcgatgaca cttgcagacc gtatcgttat tatgtcagct actaagaacc
    11761 ctgctggtac aggtactatc ggacgtgtag aacaaatcgg tactcctcaa gaagtttaca
    11821 aaaatccagt taacaaattc gttgcaggat tcatcggaag cccagctatg aacttcatca
    11881 acgtgaaatt ggttggtagc gaaattgttt ctgacggttt ccgtttgaaa gtgccagaag
    11941 gagcattgaa agttcttcgt gaaaaaggct acgaaggaaa agaattgatc tttggtatcc
    12001 gtccagaaga cgtgaatgca gaacctgctt tccttgaaac attcccagac tgtgttgtaa
    12061 aagcgactat ctctgtatca gaactgcttg gttcagaatc tcacctttac tgccaagttg
    12121 gtaaagacga gtttgttgca aaagttgatg ctcgtgacta cttgcaaaca ggtgcaacag
    12181 ttgagcttgg atttgacttg aacaaagcac acttcttcga tgtagaaact gaaaaaacaa
    12241 tctactaaaa taaataaaat tcaaagcact acaagaaaag atatctcttt atcaattgta
    12301 gtggagagat atcagttaat ctagggagag aaacaaaatg cttctctcct ttttgctagg
    12361 gaagtcatat tatgcatcta tattgtgatg ctctttaata ctcttcgaaa atctcttcaa
    12421 accacgtcaa cgtcgccttg ccgtacgtat gattactgat ttcgtcagtt ttatctgcaa
    12481 cctcaaagat gtactttgag cagcttacgg ctagtttcct agtttgctct ttgatttcca
    12541 ttgagtatta tttgtgggta ccatctacaa gtgaagctat atgcgtaaac tacgtgagca
    12601 attgaattcg aactagagag gtaataataa atttatgcta tagttatggt gacttgtatg
    12661 cttttgattc tagtttatca aataatagat tagaattgtc agataatatc attttgtgtt
    12721 ataatgaaga aaaaacagag gtgttcaaat gtcagaagca ggtcataagt ttttagcaaa
    12781 attggggaaa aaacgcttac gtccaggtgg aaagcgtgct acagattggt taattgcaga
    12841 aggaggattg tcaaaagaaa agagaatact agaggttgcg tgtaataggg gaactacagc
    12901 aattgagttg gcacagcgtt ttggttgcaa gataactgct gttgatatgg atgctcaagc
    12961 tttagaagtg gctaaaaaat ctgctggaac ggcaggtgtt gctcatttaa tcagttttga
    13021 aagagcaaat gcaatgaaac ttccttatca agatgctagt tttgatattg ttataaatga
    13081 agctatgctg actatgcaag ccgatcaagc taagaaaaaa tgtgtaatgg aatatctaag
    13141 ggtattaaaa cctggaggtc ttcttttgac acatgatgtg cttcttaagg aagctaaaga
    13201 gtctatcaga caggaattat cacaagcaat tcatgtaaat gtaggtcctt taactcaaga
    13261 tggttgggaa caggtgatga tagaatcagg ttattgtgat gtgaaagtat tgactggtga
    13321 aatgacatta atgaaattat cgggtatgat ttatgacgaa ggttggctag gaactttgaa
    13381 aatttgtgta aatgcttgta aaaaggagaa tagaaagcag tttttaacta tgtataaaat
    13441 gtttgctaag aataaacaga aattgggctt tattgcgatg gctagttata aatcgtcaaa
    13501 acgttagata attattgaag ttaacttttc cttttttctt tcttaaaaaa tatgctataa
    13561 tagagagtga aaaactttga aagaaagaaa aagatgaatt taaaagatta cattgcaaca
    13621 attgaaaatt atccaaagga aggcattacc ttccgtgata ttagtccttt gatggctgat
    13681 ggaaatgctt atagctacgc tgttcgtgaa atcgttcagt atgctactga caagaaagtc
    13741 gacatgatcg tgggacctga agctcgtgga tttatcgtgg gttgtccagt tgcctttgag
    13801 ttgggaattg gttttgcgcc tgttcgtaag ccaggtaaat tgccacgcga agttatttct
    13861 gctgactatg aaaaagagta cggtgtcgat accttgacta tgcacgcgga tgccattaag
    13921 ccaggtcaac gtgttcttat tgtagatgac cttttggcga caggtggaac tgttaaggca
    13981 actatcgaga tgattgaaaa acttggtggt gttatggcag gttgtgcctt ccttgttgaa
    14041 ttggatgaat tgaacggccg tgaaaaaatc ggtgactacg actacaaagt tcttatgcat
    14101 tattaatgaa aacagtccct agggctgttt tctctacact aggatataaa aatagactat
    14161 aactagttag agaaaaacta taattgaaaa ctatatcttc ttgcagtata ataaaaggac
    14221 taagtgtttg agatttgtct tcaaacacat gcaattattc ctgagagagt acagttagga
    14281 gagggttatg ccgattcgaa ttgataaaaa attgccagct gttgagattt tacggacaga
    14341 gaatatcttt gtcatggatg atcaacgtgc tgcccaccaa gatatccgtc ctttgaagat
    14401 tttaatttta aatctcatgc cacagaaaat ggtcacagag acccagttgt tgcgtcactt
    14461 ggctaataca cccctacaac tggatattga ttttctctat atggagagcc accgttctaa
    14521 aacaactcgt tcagagcaca tggagacctt ctataaaact tttcctgaag tcaaggatga
    14581 gtattttgat gggatgatca tcacgggtgc tccagttgag catttaccat ttgaggaagt
    14641 ggactattgg gaggaattta ggcagatgct tgagtggtct aagacacatg tctattcgac
    14701 ccttcatatc tgttgggggg ctcaggctgg gctttatctg cgctatggtg tagaaaaata
    14761 ccagatggac agtaagctat caggtattta tcctcaggac accctaaaag agggtcacct
    14821 tctatttaga ggctttgatg atagctatgt atcccctcat tcacggcaca cggagatttc
    14881 taaggaagag gtcttaaaca agaccaatct cgagatttta tcagaaggac ctcaggttgg
    14941 ggtttctatt ttggccagtc gtgatttacg agaaatttat agttttggtc atttggagta
    15001 tgaccgtgat accttggcaa aagagtattt tcgagatcgt gatgcaggtt tcgacccaca
    15061 tattccagaa aattacttta aagatgatga tgttaatcag gtaccttgtc tttgttggtc
    15121 ttcatctgca gccctctttt tcagtaattg ggtaaaccat gcggtctatc aggagacgcc
    15181 ttttgattgg agaaagatag aagatgatgc atctgcatat gggtatttat aagaggaatt
    15241 atgacatatt tagacgcttt taaatcaggt accttggttt taccgagtgc cctgctcttg
    15301 cattttaagg aactctttcc ttctagcgac gattttctgg tttggcaatt tttctatttg
    15361 caaaatacga caggcttaga agaaatgtcg ccaagccaga ttgctgaaag gattggcaag
    15421 gaaatttcgg atgtcaacca gtccatttct aatctgacgg aaaggggact gctccagtat
    15481 cgtactatcg aattaaatgg cgaaattgaa ttgctctttg atgctagttt ggccttggaa
    15541 cgtttggatg acctgtttgg agcagttcgt tcaagttcag accagctaac acctcaaaac
    15601 cagctcaagg atttggtgga aaccttccag caggagttgg gacgattgtt gacgcctttt
    15661 gagattgagg atttgaccaa gacactaaag gaagatggaa ccagtgctga cttgattaag
    15721 gaggctcttc gtgaagctgt tttgaatgga aaaccaaact ggaagtacat tcaggcgatt
    15781 ttgagaaact ggcgccatga aggaatcaag agtgtggctc aaattgaggc caagagagca
    15841 gaaagagaag caagcaatcc tcagttgaca caggtatctg cagatttcag aaatgccatg
    15901 gatctctgga aggattaatc catgcaagta ggcttgaaat ccgagtaaga tttgcaagct
    15961 gtgtataatt gtgatagaat aaatagaaaa taaattgaaa aaagaggtat gtgaaatgtc
    16021 acgtaaacca tttatcgctg gtaactggaa aatgaacaaa aatccagaag aagctaaagc
    16081 attcgttgaa gcagttgcat caaaacttcc ttcatcagat cttgttgaag caggtatcgc
    16141 tgctccagct cttgatttga caactgttct tgctgttgca aaaggctcaa accttaaagt
    16201 tgctgctcaa aactgctact ttgaaaatgc aggtgctttc actggtgaaa ctagcccaca
    16261 agttttgaaa gaaatcggta ctgattacgt tgttatcggt cactcagaac gccgtgacta
    16321 cttccatgaa actgacgaag atatcaacaa aaaagcaaaa gcaatctttg cgaacggtat
    16381 gcttccaatc atctgttgtg gtgaatcact tgaaacttac gaagctggta aagctgctga
    16441 attcgtaggt gctcaagtat ctgctgcatt ggctggattg actgctgaac aagttgctgc
    16501 ctcagttatc gcttatgagc caatctgggc tatcggtact ggtaaatcag cttcacaaga
    16561 cgatgcacaa aaaatgtgta aagttgttcg tgacgttgta gctgctgact ttggtcaaga
    16621 agtcgcagac aaagttcgtg ttcaatacgg tggttctgtt aaacctgaaa atgttgcttc
    16681 atacatggct tgcccagacg ttgacggtgc ccttgtaggt ggtgcgtcac ttgaagctga
    16741 aagcttcttg gctttgcttg actttgtaaa ataatcagta agtagcaaaa gctaggtgga
    16801 acagcattca gatgtctgtt acatttttta taggagagga aagattgaaa acaaaaattg
    16861 gattagcaag tatctgttta ctaggcttgg caactagtca tgtcgctgca aatgaaactg
    16921 aagtagcaaa aacttcgcag gatacaacga cagcttcaag tagttcagag caaaatcagt
    16981 cttctaataa aacgcaaacg agcacagaag tacagactaa tgctgctgcc cactgggatg
    17041 gggattatta tgtaaaggat gatggctcta aagctcaaag tgaatggatt tttgacaact
    17101 actataaggc ctggttttat attaattcag atggtcgtta ctcgcagaat gaatggcatg
    17161 gaaattacta cctgaaatca ggtggatata tggcccaaaa cgagtggatc tatgacagta
    17221 attacaagag ttggttttat ctcaagtcag atggggctta tgctcatcaa gaatggcaat
    17281 tgattggaaa taagtggtac tacttcaaga agtggggtta catggctaaa agccaatggc
    17341 aaggaagtta tttcttgaat ggtcaaggag ctatgatgca aaatgaatgg ctctatgatc
    17401 cagcctattc tgcttatttt tatctaaaat ccgatggaac ttatgctaac caagagtggc
    17461 aaaaagtggg cggaaaatgg tactatttca agaagtgggg ctatatggct cggaatgagt
    17521 ggcaaggcaa ctactatttg actggaagtg gtgctatggc gactgacgaa gtgattatgg
    17581 atggtgctcg ctatatcttt gcggcctctg gtgagctcaa agaaaagaaa gatttgaatg
    17641 tcggctgggt tcacagagat ggtaaacgct atttctttaa taatagagaa gaacaagtgg
    17701 gaaccgaaca tgctaagaaa atcattgata ttagtgagca caatggtcgt atcaatgatt
    17761 ggaaaaaggt tattgatgag aacgaggtgg atggtgtcat tgttcgtcta ggttatagcg
    17821 gtaaagaaga caaggaattg gcgcataaca ttaaggagtt aaaccgtctg ggaattcctt
    17881 atggtgtcta tctctatacc tatgctgaaa atgagaccga tgctgagagt gacgctaaac
    17941 agaccattga acttataaag aaatacaata tgaacctgtc ttaccctatc tattatgatg
    18001 ttgagaattg ggaatatgta aataagagca agagagctcc aagtgataca ggcacttggg
    18061 ttaaaatcat caacaagtac atggacacga tgaagcaggc gggttatcaa aatgtgtatg
    18121 tctatagcta tcgtagttta ttacagacgc gtttaaaaca cccagatatt ttaaaacatg
    18181 taaactgggt agcggcctat acgaatgctt tagaatggga aaaccctcat tattcaggaa
    18241 aaaaaggttg gcaatatacc tcttctgaat acatgaaagg aatccaaggg cgcgtagatg
    18301 tcagcgtttg gtattaagcg atgatttgaa agagggatgt gatagtagca ccctcttttt
    18361 ctttgtttta tgatagttca tcctcgagta aattcaagtt cttgctcgga aatgaagctt
    18421 atatagtaga ttgaatatag acaaatacct tgtgattggt aaaacatttt agaaattcat
    18481 ttacctttcc taatcgactt ggtttcatct tatttcaatc tattatagta ttggggaatt
    18541 tcttcaaacc acatcagctt ggtcagttct acctgcgacc tcaaaacttg tgctttggtc
    18601 aagctgggtt tagtttccta gtttgctgat ggatttccat tgactataag catccaaccc
    18661 tctttttgtc ttctaaagaa ttcttaaatt atcagtctat tgcaactttt ctcatataag
    18721 ttctttgtct tgctattggt tttccttagt agtatactaa ggtagtaatc attaagaagt
    18781 ggttacaaaa aataatgaat gaggtaaaga aaatggtaga attgaaaaaa gaagcagtaa
    18841 aagacgtaac atcattgaca aaagcagcgc cagtagcatt ggcaaaaaca aaggaagtct
    18901 tgaaccaagc tgttgctgat ttgtatgtag ctcacgttgc tttgcaccaa gtgcactggt
    18961 atatgcatgg tcgtggtttc cttgtatggc atccaaaaat ggatgagtac atggaagctc
    19021 ttgacggtca attggatgaa atcagtgaac gcttgattac actcggtgga agcccattct
    19081 ctacattgac agagttcctt caaaatagtg aaatcgaaga agaagctggt gaataccgta
    19141 atgttgaaga aagcttggaa cgtgttcttg ttatctaccg ttacttgtca gaacttttcc
    19201 aaaaaggttt ggatgtcact gatgaagaag gtgacgatgt gacaaacggt atctttgcag
    19261 gcgctaaaac tgaaacagat aaaacaattt ggatgcttgc agccgaactt ggacaagcac
    19321 ctggtttgta agaaataagg aaacatagat aaatctgtag gaaatttctt acagattttt
    19381 tctattttgt aagctattcc aaaccagtct ttttttgagt tttttgataa aatagtacta
    19441 tcagtgaaaa ggatggaagc atgactaaga aaatcgtagc tatttgggcc caggatgaag
    19501 agggtgtgat tggtaaggaa aatcgtctgc cttggcattt gccagcagaa ttgcagcact
    19561 ttaaagaaac aactctgaat catgctatct tgatggggcg tgtgaccttt gatgggatgg
    19621 ggcgtcgctt gcttccaaaa cgggaaacct tgattttgac gcgtaatccg gaagaaaaga
    19681 tagatggggt tgctactttt caggacgtcc agtctgttct tgactggtat caggctcaag
    19741 aaaagaatct ctacattatc ggtgggaagc aaatttttca ggcttttgaa ccttaccttg
    19801 atgaagtgat tgtcactcac attcatgctc gggtggaagg agatacctat ttccctgaag
    19861 aacttgactt gtctcttttt gagacagttt caagcaaatt ttacgccaaa gatgagaaga
    19921 atccttatga ttttaccatc caataccgca agagaaagga agtctaatgg aacggagttt
    19981 atttggtcta ttcacggctt ttctgtgttt catctgcttt ctggcaggag cacaagcttt
    20041 tcgtaaaaag cgttacgggc tttctatcct cctttggtta aatgccttta ccaatctggt
    20101 caatagtatt catgcttttt acatgacctt attttagata gaatgacagt atagaatgga
    20161 aggaaatcat gtctacaaat agaaaaaatg atatgatggt ttattgctca ttttgtggca
    20221 aaaaccaaga agaagtacaa aaaataattg ctggcaacaa tgcttttatt tgtaatgaat
    20281 gcgtggagtt agctcaggaa atcattcgag aagaattggt tgaggaagtc ttggcagact
    20341 tgtctgaggt gccaaaacca attgaactcc tccatatctt gaaccactat gtaattggtc
    20401 aagatcgtgc caagcgtgcc ttggcagtgg cggtttataa ccactacaaa cgcatcaatt
    20461 tccacgatac acgcgaagag tcagaagatg tggatttgca gaagtcaaac attttgatga
    20521 ttggcccaac tggttcaggg aaaactttcc ttgcccagac cttggctaag agcttgaatg
    20581 taccttttgc tattgcggat gcgacagctc tgacggaggc tggttatgtg ggtgaggatg
    20641 tggaaaatat actcctcaaa ctcttgcagg ttgctgactt taacatcgaa cgtgcagagc
    20701 gtggcattat ctatgtggat gaaattgaca agattgccaa gaagagtgag aatgtgtcta
    20761 tcacacgtga tgtttctggt gaaggggtgc aacaagccct tctcaagatt attgagggaa
    20821 ctgttgctag cgtaccgcct caaggtggac gcaaacatcc acaacaagag atgattcaag
    20881 tggatacaaa aaatatcctc ttcatcgtgg gtggtgcttt tgatggtatt gaagaaattg
    20941 tcaaacaacg tctgggtgaa aaagtcatcg gatttggtca aaacaataag gcgattgacg
    21001 aaaacagctc atacatgcaa gaaatcatcg ctgaagacat tcaaaaattt ggtattatcc
    21061 ctgagttgat tggacgcttg cctgtttttg cggctcttga gcaattgacc gttgatgact
    21121 tggttcgcat cttgaaagag ccaagaaatg ccttggtgaa acaataccaa accttgcttt
    21181 cttatgatga tgttgagttg gaatttgacg acgaagccct tcaagagatt gctaataaag
    21241 caatcgaacg gaagacaggg gcgcgtggac ttcgctccat catcgaagaa accatgctag
    21301 atgttatgtt tgaggtgccg agtcaggaaa atgtgaaatt ggttcgtatc actaaagaaa
    21361 ctgtcgatgg aacggataaa ccgatcctag aaacagccta gaggtgacta tggaacttaa
    21421 tacacacaat gctgaaatct tgctcagtgc agctaataag tcccactatc cgcaggatga
    21481 actgccagag attgccctag cagggcgttc aaatgttggt aaatccagct ttatcaacac
    21541 tatgttgaac cgtaagaatc tcgcccgtac atcaggaaaa cctggtaaaa cccagctcct
    21601 gaactttttt aacattgatg acaagatgcg ctttgtggat gtgcctggtt atggctatgc
    21661 tcgtgtttct aaaaaggaac gtgaaaagtg ggggtgcatg attgaggagt acttaacgac
    21721 tcgggaaaat ctccgtgcgg ttgtcagtct agttgacctt cgtcatgacc cgtcagcaga
    21781 tgatgtgcag atgtacgaat ttctcaagta ttatgagatt ccagtcatca ttgtggcgac
    21841 caaggcggac aagattcctc gtggtaaatg gaacaagcat gaatcagcaa tcaaaaagaa
    21901 attaaacttt gacccaagtg acgatttcat cctcttttca tctgtcagca aggcagggat
    21961 ggatgaggct tgggatgcaa tcttagaaaa attgtgagga aaagaaaatg gcaaaaacaa
    22021 ttcatacaga taaggcccca aaggctatcg gaccctatgt tcaaggaaaa atcgttggca
    22081 accttttgtt tgctagcggt caagttcccc tatcccctga aactggggaa attgtaggag
    22141 agaatatcca agaacagaca gagcaagtct tgaaaaacat cggtgctatt ttggcagaag
    22201 caggaacaga ctttgaccat gttgtcaaaa caacttgctt cttgagcgat atgaacgact
    22261 ttgttccttt taatgaggtt taccaaacgg ccttcaaaga ggaattccca gctcgttcag
    22321 ctgtggaggt agctcgtctt cctcgtgatg taaaagtcga aattgaagtc atcgcagaga
    22381 ttggataagc tagttgaagt ttggtgttgc caaacttctt ttgatataag gagaaaaaga
    22441 tgacaaagaa acaacttcac ttggtgattg tgacagggat gagtggcgca gggaaaactg
    22501 tagccattca gtccttcgag gatctaggtt atttcaccat tgataatatg ccgccagctc
    22561 tcttgcctaa gtttttgcag ctggttgaaa ttaaggaaga taatcctaag ttggctttgg
    22621 tagtggatat gcgtagccgt tctttctttt cagagattca agctgttttg gatgagttgg
    22681 aaaatcaaga tggtttggat ttcaaaatcc tctttttgga tgcggctgat aaggaattgg
    22741 tcgctcgtta caaggaaacc agacggagtc acccactagc agcagacggt cgtattttag
    22801 atggaatcaa gttggaacgt gaactcttgg cacctttgaa aaatatgagc caaaatgtgg
    22861 tggatacgac tgaactcact ccacgtgaac tgcgcaaaac ccttgcagag cagttttcag
    22921 accaagaaca agcccagtct ttccgtatcg aagtcatgtc tttcggattt aagtatggaa
    22981 tcccgattga tgcggacttg gtctttgatg tccgtttctt gccaaatccc tattatctac
    23041 cagaactgag aaaccaaacg ggtgtggatg aacctgttta tgattatgtc atgaaccatc
    23101 ctgagtcaga agacttttat caacatttat tggccttgat tgagccgatt ctgccaagtt
    23161 accaaaagga aggtaagtcc gttttgacca ttgctatggg atgtacgggt ggacaacacc
    23221 gtagtgtggc atttgctaaa cgcttggcgc aggacttatc caagaattgg tctgttaatg
    23281 aagggcatcg cgacaaagac cgcagaaagg aaacggtaaa ccgttcatga gaaaaccaaa
    23341 gataacggtg attggtggag ggactggaat tcccgtcatt ctaaaaagtc tgcgggaaaa
    23401 agatgtggaa atcgcagcta tcgtgacggt ggcagatgat ggtggttctt caggtgaact
    23461 ccgaaaaaat atgcaacagt tgacaccgcc aggtgatctt cgtaatgtcc ttgtggccat
    23521 gtcggatatg cctaagtttt atgagaaggt ctttcagtat cggttctctg aggatgccgg
    23581 agcctttgct ggccatccat tgggaaatct catcattgct ggcttgtcag aaatgcaggg
    23641 ttcaacctat aatgccatgc agttattgag caaatttttc catacaacag ggaaaattta
    23701 tccttccagt gaccatcctt tgacccttca tgcagtcttt caggatggga cagaagtggc
    23761 tggagagagt catattgtag accatcgagg cataattgac aatgtctatg tgaccaatgc
    23821 cctaaacgat gatacgcctc tggccagccg tcgagtagtg cagaccatcc ttgaaagtga
    23881 catgattgtc ctagggccag gttccctctt tacctctatt ttgcccaata tcgtgattaa
    23941 ggaaattggg cgggctcttt tggaaactaa ggcagaaatt gcctatgtct gcaatatcat
    24001 gacccaacgt ggggagacgg aacactttac agatagcgac cacgtggaag tcttgcatcg
    24061 tcaccttggt cgccctttta tcgacactgt cttggtgaat attgaaaaag tgcctcagga
    24121 atacatgaat tccaaccgtt ttgatgaata cttggtgcaa gtggaacacg attttgtagg
    24181 tctttgtaag caagtttcgc gcgtgatttc atctaacttc cttcgtctgg aaaatggcgg
    24241 tgccttccac gatggagatt tgattgtgga cgagttgatg cgcattatac aggtgaaaaa
    24301 atgagtttca cagtagcagt aaaagaagaa atcctgggcc aacaccatct gagccggcat
    24361 gaattatctg ccattatcaa aatgtctggt agcatcggtc tctcgacttc gggcttgact
    24421 ttgtcagttg tgacagaaaa tgccaaactg gcccgtcacc tctatgagtc ctttctccat
    24481 ttctatgaaa tcaaatctga aattcgtcac caccaacgga gcaatcttcg caagaatcgc
    24541 gtctataccg tttttacaga tgaaaaggtg caggatttgt taagtgattt gcacttggca
    24601 gactctttct ttggcctgga aacaggtatt gatgaggcga ttttatcgga tgaggaagca
    24661 ggtcgtgcct atctctgtgg cgctttcttg gcaaatggga gcattcgtga ccctgagtca
    24721 ggcaagtacc agttggaaat cagttctgtt tatctggacc acgcgcaagg aattgcctcc
    24781 cttctccaac agtttttact ggatgccaag gtgcttgagc gcaagaaggg ggctgtgacc
    24841 tatctccagc gagcagaaga cattatggac ttcttgatag taatcggagc catgcaggca
    24901 cgtgatgatt ttgagcgggt taagattttg cgagaaaccc gtaacgacct caatcgggct
    24961 aataatgccg agacagctaa tatcgctcgg acagtttctg ccagcatgaa gaccattaac
    25021 aatatcagta aaataaaaga tatcatgggc ttagaaaatt tgccagtaga tttgcaggaa
    25081 gtggcgcaac tgaggattca gcacccagac tactctatcc agcagttagc agatagtctc
    25141 agcacccctc tgaccaaaag tggtgtcaat cacagactca gaaaaatcaa taagatagcg
    25201 gatgaattat aaaaccacga atcctatgtg actcgtggtt cttttttata aactggtaga
    25261 gtgttttggt tgtacttttt gttcagggtc aatgtagttg atagcgttgt tgacagcagt
    25321 tggagcttct ccgaggcctg tcgcaatcag atcaattttt ccgtcatagt agcagcagtc
    25381 accgatagca tagatacctg cttggctgga ttcctgtttg ctgttgacga taatcttgtg
    25441 acggttgagg tcgagccccc agtttttaag gttaccgaca gaagatttga aaccatagtt
    25501 gacaaagagg tggtctaggt caatggtttc agtttcatca gatttgactt ttgtgatttc
    25561 aagtttatca agtgtttttc catttccaag gagttggcta ggggcgaatg gtgtcttgat
    25621 ggttacagat gattcttgca aggcttgaac actgtgttcc aaggcacgga aattatctct
    25681 gcggtgaaca agggtagttg gtgcgatttt ttcaaaagcc aaagtccaat ccacagccga
    25741 gtctccccca ccaagaatcg tcactttttt accagcgtat tgctgaatgt tagaaacgtg
    25801 gtagtggata ttttcatagc cctcaacccc ttcaagttcc agcggacgtg gtttgaaggc
    25861 accgccaccc atagcgatga taactgtttt agtcaggtga cttcctttag aagttgtgat
    25921 ggcaaattct tcttcttgtt tgtcaatctc aagaaccgtt tcattgagat gaataggggt
    25981 atcaaatcca tttagctgtt caatcaagcg gttagtcaac tcttctccag tcaggtttgg
    26041 gaagcctggt acgtctagga tttccttttc agggtagaga atagcaggtt gtccacctag
    26101 ctggggaaga gagtcgatga tttgaacctt ggcttggcgt aggtgggcat aaaaggctgc
    26161 aaaaagcccg acaggaccac cacccacaat ggtaatatca tagagttgag acatagtttc
    26221 tcctttgttt tttctagtca gtttatttta tcatattttt gttcaatgta aaatggacta
    26281 ggatagggaa aaaaatgcca gaaaatggta taataggacg aaagtgtttt gatagggagg
    26341 atatcaggga tgaattttca acaattatcc aatttgcaat attggaccag tttgtttgca
    26401 agtccatgga cgatagctat caatctgatt gatattttga ttgttgctta tattttatac
    26461 cattttacaa aagctattgc aggaaccaag attatgattt tggtacgtgg agttttggta
    26521 tttattttag ctcaaatcct tgcaaatatg attggtttga ctacgatttc ttggttaatc
    26581 aatcaaatta ttacttatgg ggttattgcg gcggttgtta tcttctctcc agagattcgg
    26641 actggtttgg aacgtttggg aagagcgaca gatttctttt ccaatgcccc tattagtgct
    26701 gaggaacaga tgattcgtgc ctttgttaag tctgttgaat acatgagtcc tcgtaaaatc
    26761 ggggccttgg ttgctattca gcgtgtacgt accttgcagg agtatatttc gacaggaatt
    26821 cccttggatg ctaagatttc tgcagaactt ctcattaaca tttttattcc caacactccc
    26881 ctacatgacg gtgcggtgat tatcaaagaa gaacgtatcg ctgtgacgtc tgcctatctg
    26941 cccttgacaa aaaacacagg gatttccaag gaatttggga ccagacaccg ggcggctatc
    27001 ggtttatcag aagtctcaga tgccttgact tttgtcgtat cagaggaaac gggaggaatt
    27061 tcgataacct ataatggaag gtttaagcac aacctaacac ttgatgaatt tgaaacagaa
    27121 ttacgtgaaa tcttacttcc aaaagaggaa gtaggtctta gttttaaaga acgattgcta
    27181 ggaggatgga aacatgaaaa aaaatagttt atatatcata tcctcactct tttttgcttg
    27241 tgtcttattt gtctatgcta cggcgacgaa ttttcaaaac agtaccagtg ctaggcaggt
    27301 aaaaacggaa acctatacta atacagtaac aaatgtccct attgacatac gctataatag
    27361 tgataagtat tttattagcg gttttgcttc agaagtatca gtggtcttga ctggtgcaaa
    27421 tcgcctatcg ctagctagtg aaatgcaaga aagtacacgt aaattcaagg ttactgctga
    27481 cctaacagat gccggtgttg gaacaattga agttcctttg agcattgaag atttacccaa
    27541 tgggctgacc gctgtggcga ctccgcaaaa aattacagtc aagattggta agaaggctca
    27601 gaaggataag gtaaagattg taccagagat tgaccctagt caaattgata gtcgggtaca
    27661 aattgaaaat gtcatggtgt cagataaaga agtgtcgatt acgagtgacc aagagacatt
    27721 ggatagaatt gataagatta tcgctgtctt gccaactagc gaacgcataa caggtaatta
    27781 cagtggttca gtacctttgc aggcaatcga ccgcaatggt gttgtcttac cggcagttat
    27841 cactccgttt gatacaataa tgaaggtgac tacaaaacca gtagcaccaa gttcaagcac
    27901 atcaaattca agtacaagca gttcatcgga gacatcttcg tcaacgaaag caactagttc
    27961 aaaaacgaat taaaaataga aaaggatttt ataacaatgg gtaaatattt tgggactgat
    28021 ggagtccgtg gagaagctaa cctagaacta acaccagaat tagcctttaa actaggacgt
    28081 tttggaggct atgttcttag tcaacatgaa acggaagcgc cgaaagtctt tgtaggacgt
    28141 gacacacgta tttcagggga aatgctagaa tcggccttgg tggcaggtct cctttcagta
    28201 gggattcacg tatacaaact tggtgtcctt gcaacaccag cagtagctta cttggttgaa
    28261 actgaaggag caagtgctgg tgtcatgatt tctgctagcc acaatccagc tcttgataac
    28321 ggaatcaagt tctttggcgg tgatggcttc aaactagatg atgaaaaaga agcagaaatt
    28381 gaagccttgc tagatgctga ggaagacact cttcctcgtc caagtgcaga aggcttagga
    28441 attttggtag attatccaga aggcttgcgt aagtatgaag gataccttgt ttcaactgga
    28501 actcctcttg atggaatgaa ggttgccttg gatacagcta atggagcagc ttctaccagt
    28561 gcccgtcaaa tctttgcaga ccttggtgcc caattgacgg ttatcgggga aacaccagac
    28621 ggtcttaaca tcaaccttaa tgttggttca acacatccag aagcccttca agaagtggtc
    28681 aaagaaagtg ggtcagctat tggtttggcc tttgatggag acagtgaccg cttgattgct
    28741 gttgatgaga atggtgacat cgtcgatggt gacaagatta tgtacatcat cggaaaatac
    28801 ctttctgaaa aaggacaatt ggctcaaaat acaattgtga caactgttat gtctaacctt
    28861 ggtttccaca aggccttgaa tcgcgaaggt attaacaagg cagttactgc agttggtgac
    28921 cgctacgttg ttgaagaaat gagaaaatca ggttacaacc ttggtggtga acagtctggt
    28981 cacgttatct tgatggatta caataccaca ggtgatggtc aattatcagc aattcaattg
    29041 actaaaatca tgaaggaaac tggtaagagc ttatcagagt tggcggcaga agtaacgatt
    29101 tatccacaaa aattagttaa tatccgagtg gaaaacgtca tgaaggaaaa ggccatggaa
    29161 gtgccagcta tcaaggccat catcgagaag atggaagaag aaatggcggg gaacggccgt
    29221 atccttgttc gtccaagtgg aacagagccc ctcttgcgtg ttatggcaga agcgcctaca
    29281 acagaagaag tggactacta tgttgatact atcacagatg tagttcgtgc tgaaattggg
    29341 attgactaaa tcctagaaaa ctagatgaaa ataaaaaatt atggtacaat agcttataat
    29401 attgtagccg atggagaaag acatgaatct taaacgtgaa caagaatttg ttagtcagta
    29461 tcattttgat gcacgtaatt ttgaatggga aaatgaaaat ggagctcctg aaaccaaggt
    29521 ggatgtgaat ttccaattgc tccaacatga ccaagaaaat caagtgactt ccttgattgt
    29581 cattttgagc tttatgattg tatttgataa gtttgtcatt agtggaacaa tctcacaagt
    29641 aaaccatatc gatggccgta ttgtcaatga accaagtgaa ttgaaccaag aagaggtgga
    29701 aaccttggct cgtccatgtt tgaacatgct caatcgtttg acttacgaag tgactgaaat
    29761 tgcattagac ttaccaggaa ttaatttgga gttctaatat gaaattagct gttttcacag
    29821 attcctctgc ttatctcagt gaagagacct tgcaaagaga agacttgttt gtcttggata
    29881 ttcctgtcaa tattgatggt gaggaatatg tcgaaggcat caatctgtct gctgaggaat
    29941 tttaccaaaa aatggctcag gcttctgaat tgcctaagac cagtcaacca agtattgcca
    30001 agttagatga gatcttaact tcgctcaaag aacaaggcta tacacatgcc ttggggcttt
    30061 tcctatcttc tggaatttca ggtttttacc aaaatatcca gtatatggtc gatgactatg
    30121 agggcttaac cattgctttc ccagacactt tgattacaag tgctccccta ggcatcatgg
    30181 ttgaaagcgt ctttaattgg cgtgatcagg gcgatgattt tgccagcatt caggataagc
    30241 tagccattca aatcagccgt acgtcagcct ttatcatggt agatgacttg gatcatttgg
    30301 taaaaggtgg acgcctttca aatggggctg ccattttggg caatttgctt agcattaagc
    30361 caatccttta ttttaacgat caaggtgtga ttgaagttta cgaaaaagtt cgtactgaaa
    30421 agaaggccac caagcgctta attgaaatta tcaaggaaac aacggcttca ggtcaatacc
    30481 gggtcattgt cattcatggg aatgctcctg aaaaggctga agaattgcgt cagcacttgc
    30541 ttgattttgg cttgggttcg gatgtttcac ttgctacatt tggtagtgtc attggaacgc
    30601 acctaggagc aggaagtatt gctctgggtt atattccagt gatttagttg gcgcttctag
    30661 gctagttaag atgccttgta tcttagaaat tgaacacgga ctacctgcct cttgaaaaaa
    30721 gatgcctgtc ttgcctttcg tggaaagtca gtgccattcc ctatttttca gaggcagcta
    30781 aggtcctttg tatcttgata attgaacacg cctggaaccc tgtgtgaaaa agatagttct
    30841 tccaagaagt agacacttct tgattggaat tcctattttc actttgtgtt cttacggact
    30901 ttgtatctta gacaggagta gagatgagta ttcgagtaat tattgccggt tttaagggaa
    30961 agatgggcca ggctgcttgt cagatggtat tgactgatcc agacttggac ttggtggcag
    31021 ttttggatcc ttttgagtct gagtcagaat ggcagggtat tcctgttttc aaggataagg
    31081 ctgatttagc tggttttgaa gcggatgtct gggtagattt tactactcca gctgttgcct
    31141 acgaaaatac acgttttgct cttgaaaatg gctttgctcc agtagttgga acgactggtt
    31201 tcacgagtga agaaattgca gagctaaaag aattttctcg tgcccaagac ttgggtggcc
    31261 tgattgcccc taactttgcc ttgggtgctg tcttactcat gcaatttgcg acgcaggctg
    31321 ccaaatattt cccaaatgtg gagattattg agctccatca tgacaagaaa aaggatgctc
    31381 cgagtggaac agccattaaa acagctgagt tgatggcaga ggttcgagag tccattcagc
    31441 aaggcgcagc agatgaggaa gagctgattg ctggtgctcg tggtgctgac tttgatgata
    31501 tgcgcatcca ctcagttcgt ttgccaggct tggtagctca tcaggaagtc atctttggca
    31561 atcagggaga agggttgacc ctccgtcatg actcctatga tcgcatctcc ttcatgacag
    31621 gagtcaattt gggaattaaa gaagttgtca agcgtcatga gcttgtctat ggattagaac
    31681 acttattatg agattaacgc aaatgccttc tgaatttcag aaggctttac cagtattaga
    31741 aaaaattaaa gaagcaggct ttgaggctta ttttgttggg ggctctgttc gagatgccct
    31801 tctccatagc cctatccacg atgtggatat tgcgacgtct tcttatccag aagagaccaa
    31861 gcagattttt ccgcgaacag ccgatatcgg aatcgagcat ggaaccgtct tggtcttaga
    31921 tggggatgag gagtatgagg taacaacctt tcggacagag gatgtctatg tggactatcg
    31981 cagacccagt gcggtttcct ttgtacgatc gctagaagaa gacctcaaac gccgtgattt
    32041 cacagtcaac gcctttgcct tggatgagac aggagaaatc gttgacttgt tccatggttt
    32101 agaagatttg gaaaagcaag tcttgcgagc agttggagtg gctagtgagc gtttcaacga
    32161 agatgcttta cggattatgc gtggtttccg ttttcaggct agtcttggtt ttgcacttga
    32221 gccagaaaca tttaaagcta tgaagacctt gacgccgctt ttggagaaaa tttctgtaga
    32281 gcgtaccttc gtcgagtttg ataaactctt gctggctcca ttttggagaa ggggcttggc
    32341 ttccatgatt gagagtcaag cttatgacta tctccctgat atggcatcta gccaggacaa
    32401 gctcaacaga ctgtttgatt tggagactga ttttactttt gaatcctctg aacaagcctg
    32461 ggcggcttta ctatgggctt tggagattga aaatgcgcag tcatttttga aatcttggaa
    32521 gacctcacgc cagtttgcca agcaagttca ggatttgctg attattttgg ctctgcgtga
    32581 aaatggagaa ttgagtaagc gagattgtta tcgctttgac atagatttgc ttttacaggc
    32641 tgaaaatctt cgtcaagctc aaggaaaaga agtcaaccca caagccatca cagaaaaata
    32701 ccaaagcttg actatccatg acaagaaaga gattcagatt aatggcgata ttttgatcaa
    32761 ggaatatggc tatcagccag gcccagactt gggagagatt ttaacagaga ttgagtttgc
    32821 cattgtcgat ggagaattgg agaataatcg tgaagccatc catgcttacc tgagggagaa
    32881 aaaatgagtg attttatcgt tgaaaaacta agtaaatccg ttggtgacaa gaccgttttt
    32941 agggatattt cctttattat ccatgactta gacagaattg gtttaatcgg tgtcaatggg
    33001 actggcaaga ccaccctttt ggacgtcctt tctggtgttt ctggatttga tggggatgtc
    33061 agtccttttt cagctaaaaa tgattaccag attggttact tgactcagga tcctgatttt
    33121 gatgatagaa agacagtttt ggatacggtt ctatctagtg aactcaagga aatccagctc
    33181 attcgtgagt atgaattgat tatgctcgac tatagtgagg acaagcaggc gcgtttggaa
    33241 cgtgtcatgg cagagatgga ctctctccaa gcttgggaaa tcgaaagtca ggtcaagacc
    33301 gttcttagca aattgggcat tcaagactta tctactcctg ttggggaatt gtcaggtggt
    33361 ctgagaagac gggtacagtt ggcacaagtc ttacttggca accacgacct cttgcttttg
    33421 gatgagccga ccaaccatct ggatattgcg attattgagt ggctgaccct ctttttgaaa
    33481 aattctaaga agaccgtcct ttttatcact cacgatcgtt atttcttaga cgctttgtca
    33541 acacggattt tcgagttgga tcgtgcaggc ttgaccgagt accagggcaa ttaccaggac
    33601 tatgttcgcc taaaggcgga acaggatgag cgcgacgcgg ctcttcttca caaaaaagaa
    33661 caactctaca aacaagaact ggcctggatg cgcagacaac cgcaggcgcg tgcgaccaag
    33721 cagcaggccc gtatcaatcg attccatgat ctgaaaaagg aagtttcagg cagtagtgct
    33781 gagacagact tgaccatgaa ctttgaaacc agtcggattg ggaagaaagt catcgagttt
    33841 caggctgttt cctttgccta tgaaaacaag cctattttgc aagattttaa tctcttggtg
    33901 caggccaaag accgtatcgg aatcgttggg gacaatggtg ttggaaaatc aaccctgctc
    33961 aacttgattg caggaagtct tgagccaact aaaggacaag ttgtgattgg ggaaactgtt
    34021 cgcatcgcct atttctctca gcaaattgag ggtttggatg aaagcaagag agttatcaat
    34081 tacctgcagg aagtggcaga agaggtcaag accagtggcg gttctacgac ttcgattgca
    34141 gagttgctgg agcagttcct tttcccacgt tcgacgcatg gaaccttgat tgagaaattg
    34201 tcagggggtg agaaaaaacg tctttatctc ctcaaactgc ttttggaaaa accaaatgtt
    34261 cttcttttag acgagccaac caatgaccta gatattgcaa ctttgacagt cttagagaat
    34321 ttcttgcaag gttttgcagg tcccgtttta acagtcagtc acgaccgcta tttcttggat
    34381 aaggtagcga ccaagattct cgcttttgag gatagcaaga ttcgtccttt ctttggtcat
    34441 tacaccgact atcttgatga aaaagctttt gaaacagata tggccaatca agtgcaaaag
    34501 gtcgaaaagg aaaaagtggt caaggttcga gaagacaaga aacgtatgac ctaccaagaa
    34561 aagcaggagt gggcaagtat tgaaggtgat attgaaacct tggaaaaacg tatcgctgct
    34621 attgaagagg aaatgcaggc taacggctct gactttggta agctggctac tctccaaaaa
    34681 gaattggatg agaaaaatga agcactcctt gaaaaatacg aacgctatga gtatctcagt
    34741 gaatttgata gttaagacta ttcgaaaatc aaagtgcaaa ctatgtcggc ttcacattgc
    34801 cgactcaagt acagcctgtg accggcttcc taatttgcac tttgattttt attgagtata
    34861 aaagaataga aaaatcccgt ctcatgaaag gatttctcta ttcttttttg gtttcttgat
    34921 gaaagatatt ttgccaggtt tcgtggcgac gccagatact ggtatggatg ataccatcta
    34981 actcatagca gatgagtttg gttttttgac tgatggaagt aatttgaatg tccttgatag
    35041 cagaatttaa ctcttttttg gtcttataag cctctttatc catctgctct ccatcttggc
    35101 gaatatagac aaaatcatca gtcaagagtt cttctagttg gtttccttgg tcaatcaatt
    35161 gttcacgcat aagcaatttt ttatagacat tgtctaaaat ttcatcctca gagataggtg
    35221 ctggttcgat atggacatcg gtatcaaaga cgccaaaacg ctcctccagc atagactcga
    35281 cctgatccgc gatttcatgg ctttcaaaaa cagacaagtc aggattcatc tctagtgtaa
    35341 tatccaggta gatgttgcta ccgtaggtgc gacctctttg cgatttgacc ttgctgattt
    35401 tgggaatttc catgatagcc ttttggtagt cctcgagcag gcggtcgtca aagccatctg
    35461 aaagactaaa ggaagactcg atgaagatat cataggcagt cttcaagata aagaaagtga
    35521 tgatgatagc aaccagttta tccacaatcg gataattgaa actactagct aggatggcaa
    35581 tggcggttcc aagtgaggta acagcgtcag aaagattgtc cttagcagct gccttcagcg
    35641 ccttggagtt ggatttctta ctgaggcgag tattgtagag atagaccaca aacataatcg
    35701 ctgcagaaat gattcctaga gttgcaccaa gaggatcaat gaccgtttct tcccgactga
    35761 gaatcttttg aatggtatct cttagaacat cgaaaccgac atagaacatg atgatagaag
    35821 tgatcaagct tgccaaatct tcaatcttcc aatgaccaaa acggtggtca cggtctgcag
    35881 gctggcgcgc catccgaatc ccgattaaga gggccacatt tccaatgatg tccgatacgt
    35941 tattaaaacc atcggccacc aaactggatg aatgaaggag atgaccagct gctaatttgg
    36001 ctgcagacaa gatcaaatag gtcgaaatac tgataatggc tccacgctca gctaacttga
    36061 gatttgagat agattgcttc attcaacttc ctttctagtc acatagcatt ctaccattat
    36121 actggttttc aaggaaaaat tcaaataagg cagtttttac tctttgaaaa ctccccaaaa
    36181 tttggtataa tggtactact caagggagta gctggcagaa acctgtgata gtgtcgtcat
    36241 tccgaatttt atgctgaaaa gtatgctttc cggccctatc ttaaacagcg agacttgtta
    36301 tgattaacag gtctcttttt gtttgtcgtg aaaagatatg acagaaagag agtctgtttt
    36361 gcacacaatg tcaaggagga gacacatgtc aaaagaacaa aaacgccaag cgttttatac
    36421 tcagagccct gaagaggtct tgcaggctgt ggatgcgacc gagcaaggtt tgtcatcaag
    36481 tgaggcggaa aagcgccttg ctgaatttgg gcacaatgaa ctcgaagaag gcgagaaacg
    36541 atcaatcttg gtcaaattca tcgagcaatt taaggatttg atgattatca tcctagttgc
    36601 ggcagcaatc ttgtcagtcg tgacttctgg tggggaagat atcgcagatg ccattatcat
    36661 cctagctgtg gttatcatca acgctgcctt tggtgtttac caagaaggaa aagctgaaga
    36721 agctattgaa gccctcaaat ccatgtctag tccagttgcc cgcgttcttc gtgatggaca
    36781 catggcagag attgactcta aagaattggt accaggcgat atcgttgccc ttgaagcagg
    36841 tgacgtggta ccagcggacc tacgtttgat agaagccaac tctcttaaaa ttgaagaagc
    36901 agccttgaca ggtgaatctg taccagtcga aaaagacttg tcagtcgagc ttgcgacaga
    36961 tgctggtatt ggtgaccgtg tcaacatggc cttccaaaac tcaaacgtaa cctatggtcg
    37021 tgggatgggt gttgttgtca atacaggtat gtacactgaa gttggtcata ttgctggtat
    37081 gcttcaagat gcggatgaga ctgatacacc actcaaacaa aatttgaaca acctttctaa
    37141 ggtcttgacc tatgctatct tggtcattgc ccttgttact tttgtagtgg gtgtcttcat
    37201 tcaagggaaa aatccacttg gtgagttgtt gacttctgtt gcccttgccg ttgcagccat
    37261 tccagaagga cttcctgcta tcgttaccat cgttctttct cttggtactc aagttttggc
    37321 caaacgacat tccatcgttc gtaagttgcc agcagttgaa acacttggtt caactgaaat
    37381 catcgcttct gataagactg gtacgctgac tatgaacaag atgacagtcg aaaaagtctt
    37441 ctacgatgcg gttctacatg actcagctga tgatattgaa ctaggtcttg aaatgccact
    37501 acttcgttca gttgtcttgg ccaatgatac gaaaatcgat gtggaaggta acttgattgg
    37561 tgacccaacc gaaacagcct ttatccaata tgccttggac aagggctatg atgtcaaagg
    37621 tttcttagag aaatatcctc gtgtagctga attgccattt gactctgacc gtaagctcat
    37681 gtcaacagtt cacccattgc cagatggtcg tttccttgta gcagtcaagg gtgcgccaga
    37741 ccaactctta aaacgttgtc ttcttcgtga taaggctggg gatattgctc cgattgatga
    37801 gaaggttaca aatctcattc atacaaacaa ttctgaaatg gctcatcaag ccttgcgtgt
    37861 ccttgcaggt gcttataaga ttatcgatag tattccagaa aatctcactt ctgaagagct
    37921 tgaaaatgat ttaattttta ctggtttgat tgggatgatt gaccctgaac gtcctgaagc
    37981 cgctgaggct gttcgtgtgg ctaaggaagc gggaatccgt ccaattatga ttacaggtga
    38041 ccaccaagac acagcggaag ccattgccaa acgtttggga atcattgacg caaacgatac
    38101 agaaggtcac gttttaactg gtgctgaact caatgaactg tcagatgaag aatttgaaaa
    38161 agtcgttggt caatactctg tttatgcccg tgtgtctcca gaacacaagg ttcgtatcgt
    38221 caaggcttgg caaaaacaag gtaaagtcgt tgccatgaca ggtgacggtg tcaatgacgc
    38281 gccagctctg aaaacagccg atatcggtat cggtatggga atcactggta cagaggtttc
    38341 taagggggct tctgatatga ttcttgcaga tgataacttt gcgactatta tcgtcgcagt
    38401 ggaagaagga cgtaaggtct tctcaaacat tcaaaagact attcagtacc tactttctgc
    38461 taatactgct gaagtattaa ccatcttcct atcaaccttg tttggttggg atgtcttaca
    38521 gccggttcat cttttgtgga ttaacttggt aacggatacc ttcccagcta tcgctcttgg
    38581 tgttgaacct gcggaacctg gtgtcatgaa tcataaacca cgtggacgca aggcaagctt
    38641 cttctcaggt ggtgttttga gttctatcat ttatcaaggt gtactccaag cagctcttgt
    38701 tatgagtgtt tatggccttg cgattgctta cccagttcat gtgggtgaca atcatgctat
    38761 tcatgcagat gccctaacga tggcctttgc aacccttggt ttgattcagc tcttccatgc
    38821 ctacaatgtc aagtctgtct accaatccat cttgacagtt ggcccattca agtctaagac
    38881 ctttaactgg tccatcttgg tatcctttat ccttctcatg gcaacaatcg ttgtagaacc
    38941 gcttgaagga atcttccacg taaccaaact agacttgtca caatggggaa ttgttatggc
    39001 tggaagcttc tcaatgatta tcatcgtcga aatcgttaag tttattcaac gcaaactcgg
    39061 ttttgacaag aatgcgattt aagggaggtt tcggatgtca gcatatcaat taccgaccgt
    39121 atggcaggat gaagctagta atcaaggagc ttttacgggg ctaaacagac caacagcagg
    39181 tgcccgtttc gaacaaaact tgccaaaagg agaacaagct tttcagcttt attcactggg
    39241 aacaccaaat ggtgtgaagg ttactatctt attggaagaa ttactagaag ctggttttaa
    39301 ggaagcggct tacgacttgt ataagattgc tatcatggat ggggatcaat tcggctcaga
    39361 ctttgtgaag ctcaatccaa attccaagat tccagcctta ttggaccagt caggtactga
    39421 aaacgtaaga gtctttgagt ctgctcatat tcttctttac cttgctgaga aatttggagc
    39481 ctttttacca agtaatcctg tggaaaaggt agaagttttg aattggctat tctggcaagc
    39541 aggtgcagca ccttttctag gtgggggatt tggacatttc ttcaattatg ctcctgaaaa
    39601 attggaatat cctattaacc gttttacgat ggaagtgaaa cgccagttgg atttattgga
    39661 taaggaattg gctcagaaac cttatattgc aggcaatgac tatacgattg cagatattgc
    39721 tatctggtct tggtatggac agttagttca aggaaatctt taccaaggtt ctgcaaaatt
    39781 cttggatgcc tcaagttatc aaaatctagt aaaatgggca gaaaaaattg ccaatcgtcc
    39841 agctgttaag cgtggcttgg aagtaactta tacagaaatt aaatagcaaa aaagtcatct
    39901 tcggatggct ttttgctaca gttgagggaa agggtttgca gttatcggct tttgtgctat
    39961 aattgctata atatagtaaa aagcaagagg agtgtgagga agtggaaaag aaaattgtga
    40021 aggatatctt atttttatct caagtgtctc atccggcaag tcaggaggac ctttatcttg
    40081 ccagagattt gcaggataca ctcttagcaa atcgtgatac ctgtgttggt ctagctgcca
    40141 atatgattgg gatgcagaag cgcgtgatta tctttaatct tggcttggtt cccgtggtca
    40201 tgtttaaccc agtgcttctg tcctttgaag gatcctatga ggcagaagaa ggctgtttgt
    40261 ccttggtagg tgtgagatca actaagcgtt atgaaaccat aaggcttgcc tatcgtgaca
    40321 gcaagtggca ggaacagacc attaccttga caggcttccc agctcagatt tgccagcatg
    40381 agctggatca cttggaagga cgaatcattt aggaggaaag caaatgaaac gaatagtctt
    40441 tgaacttatt tttatcgcaa cgacctggta tatcttttta ccgcccctta acctgaccag
    40501 ctgggaattt ctcttcttcc tctgtgggca tttgttagtt gtggcaatct tatttggctt
    40561 tggcaagggg ataaaccttg tcaaaacggt tcatgtgcgc cacggtaagg cggaagctgc
    40621 cttaaatctt gagggtttca aaatcaatcg gttagggaaa attctgttag cttcgattgg
    40681 aggaattctt ctcttggcag ctttggtttc cttggtaact tctagcatgt ttcaggctaa
    40741 aaattatgcc aatgtagtca cggttacgga aaaagacttt actgaatttc ctaagagtga
    40801 caccagtaag gttcctatcc tagatagaag tactgctgaa aaaattggag accgctactt
    40861 gggttcccta accgataagg tgtcgcaata cgtagcggca gatacctata cccaattgac
    40921 aattgatggg aaaccttatc gggtcacacc actagaatat gcagacccta tcaaatggtt
    40981 taacaatcaa gccaagggaa tcggtgagta tatcaaggtg gacatggtaa ctggaaatgc
    41041 ggatttggtg gacttgaaga caccaatcaa gtattcagac tcggagtatt ttaaccgtga
    41101 tgtcaaacgt cacctgcgct tgaagtaccc gaccaaaatc tttaaaactc catcttttga
    41161 ggtggacgat gagggcaatc ctttctatgt agcaacggtt taccaaaagc aatttggact
    41221 tgctgttcct cgtcctgctt cagtcattat cttggatgct acaaatggag aaaccaagga
    41281 atacagctta tcagatgttc cagaatgggt ggacaggatc tatccagcag aggaaaccat
    41341 tgagcaaatc aactacaacg gcaagtacaa ggacggtttc ttgaatgcca tgatttccaa
    41401 gaaaaacgtg acccagacga ccaatggcta taattacttg tctatcggta atgacatcta
    41461 tctctacaca ggtgtgacgt cggctaatgc ggatgagagt aatcttggtt tcatccttga
    41521 aaatatgcga acaggagaaa ttactaagta tagcttggct tctgcgacag aagaatcagc
    41581 ccgtgaatca gcagaaggtg ctgttcagga gaaatcctac aaagcaacct tcccaatcct
    41641 catcaacctc aatgacaagc ctctctacat catgggctta aaggacaatg ctggcttggt
    41701 caaagagtac gccctggtag acgcagtcga gtaccaaaat gttatcgttg ctactacagt
    41761 ggaagagatg ctcagcaagt atgccaataa aaacgacctt gaaattgaca atgcaacgac
    41821 agaaagcatc aagggagtag tagcagacct caaatcagct gttatcaagg gagacactgt
    41881 ctacttcttt aaagttgatg gcaagatata caaggtaaag gcttcagtat ccgatgacct
    41941 tccttacctt gaaaatggta aaaccttcga aggtcaagta ggaaaagaca attatctcaa
    42001 gacctttaaa gtacaataat actcttcgaa aatctctagc tctatctgca acctcaaaac
    42061 agtgttttga gcagcctgcg gctagtttcc tagtttgctc tttgattttc attgagtata
    42121 aaaaaggttt atttaataaa tatatgttat aataaggtaa attaagccta atggaggaca
    42181 aagaaatggg tttttatttg atggttgctt caatgctact cggactgctc gctttgaaga
    42241 taggtttttc tcagttcaag gagaaaaaag ataaattctt atctatctta acaagtttag
    42301 ctggcacagc ccttgttctc gtggctgtct ggttaggatg gcccaaataa atagaaaaac
    42361 ctcggtcaaa ccgaggtttt tcaaatgaat ttcttggttg tggctaaaaa atatgctaca
    42421 ctatcaatat gaaaatttta atcccaacag caaaagaaat gaacacagac ttgccaagta
    42481 tcgaggcaat tcctttaaaa ccagaaagtc agaccgtgct tgatgccttg gctctctatt
    42541 ctgccagtca attggagagt ttctacaagg tatcagctga gaaagcggcg gaagaatttc
    42601 aaaatatcca agctttgaaa aggcaaactg ctcaacacta tccagccttg aaactttttg
    42661 atgggcttat gtaccgcaac attaagagag ataagctgac cgaggcggaa caagattatc
    42721 ttgaaaatca tgtcttcatt acctcggctt tgtacggtgt tgttccagcc ttgtcaccca
    42781 tggctcctca ccgtttggat tttttgatga aattaaaagt cgctggtaag actttgaaga
    42841 gccattggaa ggcagtctat gatgaagctc tgaagaagga agaagtgatt ttctctctct
    42901 tgtcatcaga gtttgagact gtattttcta aggaaatcag agcaaagatg gtgaccttca
    42961 aattcatgga ggatagaggc ggtcagctga agattcactc aactatctcc aagaaagcgc
    43021 gcggggcctt tctaacagct ttaatagaaa atcaagtaca aactgtgggg gaagcacgtc
    43081 gcttgaactt tgctggattt gtttaccgag aagatttgtc acaaccacag ggattggttt
    43141 ttgtaaagga agtatagaaa tcagataaga gaaaagtcag cacgattatg ctgacttttt
    43201 tgataactta taaagtattg gacaaatgaa tctcatttga taaggtgtta agatgattaa
    43261 ccaaattcat gattgacaga tgatttcggc aaataaactt cttggtaatc cctgaaatat
    43321 agaaattaga cacgatgata tcgtaatctg tctgatttaa aatctcagga cttgttttta
    43381 attcatccca aatatcgaag gtaaagcggt tattacagta ataggaaagc atatcaacaa
    43441 aggtaaggga tatagcatgg tcaaagttac tgataatcaa aaccttgata ggtggtcgat
    43501 tttctaacaa ctgagtagag aggttttcag catgggttaa gatggtgtac atcaagtgtt
    43561 ccaactgttc aggatggtca tgctgtccaa ttgcctgacg gtattgagcc agttcttgac
    43621 gcgcacttcc cataaagtct gggaagtaac cttcaaattt tttaatcgtc aatgcttttt
    43681 gttcaaataa gattggggta gaaaagattt cctgtctttc aaagaaagca gtgttgtgta
    43741 aatgccaaat cagctcatcg tggttagtaa aagtaatctt atattgtttt gataggcgtt
    43801 ctaatatttg actaagtaat tggtaagagt atcttgcttg actgttatct tctaaagagt
    43861 tgaagaattc ttgaggatct aggaaaatat cattctgaag aaaagaaata aaaatttgag
    43921 cgattgtatc tggagtcatt tcaagcccaa aatgtttaga gaaataagca agtgtctcct
    43981 ggaaatttgg aatgctcttt aaaagaggat aatattcttt gtaaaagtgg ttggggaggt
    44041 caatgaagtg accattttta accctgtgga tactgatagc tatcatcagt ttgtacattc
    44101 tataaattga aaatcgcatt ggataattcg tgattttata gaagaagtca gcaaactctg
    44161 ttaaatcttc ctcaggaagg tcaggaaaag gccaatctag gaaataatag cgctcagaaa
    44221 agtattgggc aaaaaagtaa cgaatatcga tctcatttcc acgtatctcg gatggagtaa
    44281 aagataattc aatttgaaac tgagatgaaa gaacctttgt aatatttctg cccagtcgat
    44341 agaggttggc actactaaag taaagatttt ctattgttcg ataaataggt agcccctcat
    44401 tgaagaacat atactctagt aattgaaaag attgagaatt agcaagaaaa tattgataaa
    44461 tatcttctac actagtgtta acttctaaat ctatcatgat tccgttaaca gaagattgga
    44521 tgttaataga tggaaaggca atacgtaatt catttaaatc actttttaag attcgttctg
    44581 tacatcctaa tttttcggct agttcatgta atttcatcca attacgattc tgaattaggg
    44641 tttccattaa gcgtaattgt ctttgaactt ttgtggataa aaggtttctc atacgggtat
    44701 ttcctccata attcattata tctttttttg tctaagtagt ataaaaaaat tagagcaaga
    44761 aaattgtcgt tagtaatcgg aaaaattaga ataatataag tggcttttaa gtgcaaaaac
    44821 agaatatatt aattgttcag aaaatattga ttaatgcctc aaatagttgt acattgtaaa
    44881 ctataaaata ctatctagga gtttaaaatg aaacattcac ataaaaaatc atttgactgg
    44941 tatagcatgc aacaacgtta ttctattcgt aagtattact ttggtgcagt tagtgtcttg
    45001 ctcggtaccg ctttggtatt aggtgcagca gctagtgtcc aaacagtaca agcggaagaa
    45061 aacaaacaag aaactaccaa tagtatttct gttggtaggg gagaagcagc tactaaacca
    45121 gcagaggttt ctgcgtctaa taaagagaaa acctatgcag ctccaactgt agctaatcca
    45181 gtagaaacga ctccagttaa aactggagaa gttactaaac cagcagaaaa agttgaagaa
    45241 gcaaaagaca aaaaagagga agtaacgcat caagatgcta ttgacaagtc aaaattgtta
    45301 acggctcttt cgcgtgctaa aaagttagaa agcaagttat atacagaagc aagtgctgct
    45361 aacttgcaaa caagtatcca agctggtcaa agcttgcttg ggaaagcaga tgcatctgaa
    45421 gctgaattat cagcagcaga gtcatctatt caatcatcta ttattggtct agaacttcgt
    45481 tctaactcta acaaaggaac tgtatcagaa actcctgtag cgaagaaagc taatatagtt
    45541 gaagcgaagg aagagactaa tccagctgca acaactgatc gttcagctgt tgatagtgct
    45601 gttttgccaa ctagcacagc tgccaaagta gaaacaactt cagctccagc atctattaat
    45661 gaaatcttga aaccaggttt gagcctttct gatgctcgcc aaaatccagc tatccgtaag
    45721 gaagatgttg atagagggta tagtggtttt agagcggcgc ctgctccaac gaaccaacca
    45781 gtaactaatc taggaaataa tactgttttc actgatatta gcagaggttc tcatactttc
    45841 cgtggtaatg gaaattcacg tcgtggaaac ccgattcatt ttgatgtaac aacaactaga
    45901 gttagaaata gagtagattt ctcaatcaga tattcaggac caggtgagtt tgttaataac
    45961 aactttatct tagacaaagg aaatggattc ggagaacctt ctcgtgcaac tgtttcaaca
    46021 ccaaaattaa gagaccaagt taaaaacatt agtaagggtg gaaactttgt ttctcattca
    46081 ggctacagtt tagaagctgc agtagaaaca agcaccaatc aaacaattaa gtttagttta
    46141 cctatagcca accctaatgg tgatctgtct gttcgattaa gacctgttac ttttaatgta
    46201 ggtcaagggg aatcaggatc tgcaactagt aatgatccat atagtaactc taactattac
    46261 ttcagagaaa aaccactcct cttggatgca aatccaaatg gtggtactaa taataagact
    46321 gtttcagaag acattgactt ccaaactgtc tatcttccaa ctagtaagtt accagaaggt
    46381 caaactagat tagttcgaga aggtgaaaaa ggacaacgtc aaatcatcta taaagttcat
    46441 caattgggta acgaaacaat cctaggattg ccaattagta attcagttat taaagaagtt
    46501 aagccacgta ttatgcaaat tggtgtggct aaagatctaa tcgatacagt aaaaccacgt
    46561 gttgatcaaa ataaagtcgg tgatacaaat aacctcactt tctatcttga taacgatgga
    46621 aacggtgttt atactgaggg cgtagacgaa cttgttcaaa aaattgctat taaagatggt
    46681 gctaaaggtg aaaaaggaga ccgaggcgaa cgcggtctaa ctggagctca aggagctaaa
    46741 ggtgaaaaag gagaccgagg tgaacgcggt ctaactggag ctcaaggagc taaaggtgaa
    46801 aaaggagacc gaggtgaacg cggtctaacc ggagctcaag gagctaaagg tgaaaaagga
    46861 gaccga
//
LOCUS       DAVBEO010000009        45807 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 009
            SAMEA1678075-rid20185393.denovo.009, whole genome shotgun sequence.
ACCESSION   DAVBEO010000009 DAVBEO010000000
VERSION     DAVBEO010000009.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678075
            Sequence Read Archive: ERR226392
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 45807)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 45807)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980207.1
            Genome Coverage       :: 150x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:50:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 72 of 147
            Pseudo Genes (incomplete)         :: 72 of 147
            Pseudo Genes (internal stop)      :: 42 of 147
            Pseudo Genes (multiple problems)  :: 32 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..45807
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678075-rid20185393.denovo.009"
                     /strain="KS 009"
                     /db_xref="taxon:1313"
     gene            <1..1122
                     /locus_tag="VQ543_000556"
     CDS             <1..1122
                     /locus_tag="VQ543_000556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HET2611334.1"
                     /translation="STSASASASTSASESASTSASTSASASASTSASASASTSASTST
                     STSASTSASTSASTSASTSASTSASESASTSASTSASTSASASASISASESASTSASA
                     SASTSASASASTSASESASTSASASASTSTSASESASTSASASASTSASASASTSASA
                     SASTSASESASTSTSASESASTSASASASTSASASASTSASASASTSASASASTSASA
                     SASTSASASASTSASASASTSASASASTSASASASTSASASASTSASASASTSASASA
                     STSASASASTSASESASTSASESASTSASASASTSVSNSANHSNSQVGNASGSTGKSQ
                     KELPNTGTESSIGSVLLGVLAAVTGIGLVAKRRKRDEEE"
     gene            1183..3268
                     /locus_tag="VQ543_000557"
                     /pseudo
     CDS             1183..3268
                     /locus_tag="VQ543_000557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000341103.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
     gene            3265..4143
                     /locus_tag="VQ543_000558"
     CDS             3265..4143
                     /locus_tag="VQ543_000558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000739288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exopolysaccharide biosynthesis protein"
                     /protein_id="HET2611335.1"
                     /translation="MKKNHLVGDALILTVSDQIEELDYLLESLPNICFYIAAPVQFSE
                     KIRSLETNYNVRLRTITNEEQLNFLVDTCDFLLDINHFQEVDAIVSKFVQAGKSVFAF
                     DNTVHGNQGQEVFLSSTPDKLVSRVRDYLNEVRVGTNHQEKIIQDGTWNVFKIDDKAH
                     FIVGANVICRNFENFHVSSGKLILHDGVFINNSCSFNCMERIEIGAGTMMGEGVRFYD
                     HDHIYTAEKIEKWQWTTAPIRVGRDCWIGSNVTILKGVTIGDNTIIGAGCLIRNDIPS
                     NSVVYNNGNLVVKRRD"
     gene            4183..4461
                     /locus_tag="VQ543_000559"
     CDS             4183..4461
                     /locus_tag="VQ543_000559"
                     /inference="COORDINATES: protein motif:HMM:NF021616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HET2611336.1"
                     /translation="MENELISIVVPIYNVENYLRQCLDSIQKQTYPNFECIMVNDGSP
                     DHSSKICEEFVEKDSRFKYFEKANGGLSSARNLGIECSGGGVHYFCRL"
     gene            4469..5059
                     /locus_tag="VQ543_000560"
     CDS             4469..5059
                     /locus_tag="VQ543_000560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase"
                     /protein_id="HET2611337.1"
                     /translation="MEHDALDRLYGALKKENADISIGRYNSYDETRYVYMTYVTDPDD
                     SLEVIEGKAIMDREGVEEVRNGNWTVAVLKLFKRELLQDLPFPIGKIAEDTYWTWKVL
                     LRASRIVYLNRCVYWYRVGLSDTLSNTWSEKRMYDEIGAREEKIAILASSDYDLTNHI
                     LIYKNRLQRVIAKLEEQNMQFTEIYRRMMEKLSLLP"
     gene            5088..6098
                     /locus_tag="VQ543_000561"
     CDS             5088..6098
                     /locus_tag="VQ543_000561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HET2611338.1"
                     /translation="MKLHLTNLYGMAGDSTVILAQNAVQKIASQLGFREVGIYFYNIA
                     SDSPSEMNKRLDGIMASISIGDILVFQSPTWNGFEFDRLLFDKLKDMQVKIICFIHDV
                     VPLMFDSNYYLMKDYMYMYNLSDVLIVPSERMKTRLMEEGLTTKKILVQGMWDHPHDL
                     SLYTPAFKKELFFAGSLERFPDLQNWSQDTPLRVFSNKGEASSSARNLSIEGWKKDEE
                     LLLELSKGGFGLVWGTYQNDGESNQYYTLNISHKVSTYLTAGIPVIVPSSLSTAKFIV
                     DQGLGFVANSLEEVHAIVDKMNLQEYQEMTNRIKTFSYLLKEGYFTKKLLVDAIYHLG
                     VE"
     gene            6108..8552
                     /locus_tag="VQ543_000562"
     CDS             6108..8552
                     /locus_tag="VQ543_000562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SP_1767 family glycosyltransferase"
                     /protein_id="HET2611339.1"
                     /translation="MIKTIVLAGDRNYIRQLETTIKSILYHNRDVKIYILNQDIMPDW
                     FRKPRKIARMLGSEIIDVKLPEQTVFQDWEKQDHISSITYTRYFIADYIQEDKVLYLD
                     SDLIVNTSLEKLFSICLEEKSLAAVKDTDGITFNAGVLLINNKKWRQEKLKERLIEQS
                     IVTMKEVEEGRFEHFNGDQTIFNQVLQDDWLELDKEFNLQVGHDVTAFYNKWENYFNE
                     LVPPSIIHFVSYRKPWTTLIANRYRDLWWEFHDLEWTKILQHHIGEFELTSSLDKEFS
                     CLTLTNSQDLEGIEELVTALPDVVFHIAAWTDMGDKLIKLAVYDNVRLHPQIVPPVLD
                     KLKKSTNLYLDINHGSADENFLKSLQEQEKTLLAFQSTQHGELGQIVFENGKVSFMID
                     TIKDFKKNGHLTCFRQLPSLTCLTFTASQDIEQLDYLAGQLPNVVFQVAAWTAMGPKL
                     YDLSNRYPNIQLYPAISRDKLDELKEKMDAYLDINLLTSTSDIVAEMAHLSKPILAFY
                     KSQNGNNGQRLYSSEHPERMLADLQKLITKDMLEKPLDIIQVKGIDETLDYIIEHNSS
                     LVRFGDGEINMLAGHSIPYQDYDEELVSIMRDIIGQESREDLVVCLPDAFTDRFRFTS
                     WAIPFWKDHMDHYMDFYRELCSDSWYGSTFVSRPYIDFEDKSQAKAQFEKLKSIWENR
                     DLLIVEGATSRSGVGNDLFDEANSIKRIICPSHSAFSRVHEIEQEIEKYAGGRLILCM
                     LGPTAKVLSYNLCQMGYQVLDVGHIDSEYEWMKMGAKTKVKFSHKHTAEYNFDQDIEF
                     IDDETYNSQIVARILN"
     gene            8583..9803
                     /locus_tag="VQ543_000563"
     CDS             8583..9803
                     /locus_tag="VQ543_000563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000938701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase family 8"
                     /protein_id="HET2611340.1"
                     /translation="MRNTKRAVAFAGDYAYIRQIETAMKSLCRHNSHLKIYLLNQDIP
                     QEWFSQIRIYLQEMGGDLIDCKLIGSQFQMNWSNKLPHINHMTFARYFIPDFVTEDKV
                     LYLDSDLIVTGDLTDLFELDLGENYLAAARSCFGAGVGFNAGVLLINNKKWGSETIRQ
                     KLIDLTEKEHENVEEGDQSILNMLFKDQYSSLEDQYNFQIGYDYGAAAFKHQFIFDIP
                     LEPLPLILHYISQDKPWNQFSVGRLREVWWEYSLMDWSVILNEWFSKSVKYPSKSQIF
                     KLQCVNLTNSWCVEKIDYLAEQLPEVHFHIVAYTNMANELLALTRFPNVTVYPNSLPM
                     LLEQIVIASDLYLDLNHDRKLEDAYEFVLKYKKPMIAFDNTCSENLSEISYEGIYPSS
                     IPKKMVAAIRSYMR"
     gene            9812..11008
                     /locus_tag="VQ543_000564"
     CDS             9812..11008
                     /locus_tag="VQ543_000564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001232144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 8 protein"
                     /protein_id="HET2611341.1"
                     /translation="MRKSIVLAADNAYLIPLETTIKSVLYHNRDVDFYILNSDIAPEW
                     FKLLGRKMEVVNSTIRSVHIDKELFESYKTGPHINYASYFRFFATEVVESDRVLYLDS
                     DIIVTGELATLFEIDLKGYSIGAVDDVYAYEGRKSGFNAGMLLMDVAKWKEHSIVNSL
                     LELAAEQNQVVHLGDQSILNIYFEDNWLALDKTYNYMVGVDIYHLAQECERLDDNPPT
                     IVHYASHDKPWNTYSISRLRELWWVYRDLDWSEIAFQRSDLNYFERSNQSKKQVMLVT
                     WSADIKHLEYLVQRLPDWHFHLAAPCDCSEELTSLSQYTNVTVYQNVLHSRIDWLLDD
                     SIVYLDINTGGEVFNVVTRAQESGKKIFAFDITRKSMDDGLYDGIFSVERPDDLVDRM
                     KNIEIE"
     gene            11008..11913
                     /locus_tag="VQ543_000565"
     CDS             11008..11913
                     /locus_tag="VQ543_000565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001292324.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HET2611342.1"
                     /translation="MSELISVVVPIYNTGKYLVECVEHILKQTYQNIEIILVDDGSTD
                     NSGEICDAFMMQDNRVRVLHQENKGGAAQAKNMGISVAKGEYITIVDSDDIVKENMIE
                     TLYQQVQEKDADVVIGNYYNYDESDGNFYFYVTGQDFCVEELAIQEIMNRQAGDWKFN
                     SSAFILPTFKLIKKELFNEVHFSNGRRFDDEATMHRFYLLASKIVFINDNLYLYRRRS
                     GSIMRTEFDLSWARDIVEVFSKKISDCVLAGLDVSVLRIRFVNLLKDYKQTLEYHQLT
                     DTEEYKDICFRLKLFFDAEQRNGKS"
     gene            11970..13187
                     /gene="secY2"
                     /locus_tag="VQ543_000566"
     CDS             11970..13187
                     /gene="secY2"
                     /locus_tag="VQ543_000566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000161857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory Sec system protein translocase subunit
                     SecY2"
                     /protein_id="HET2611343.1"
                     /translation="MTKIYSSIAVKKGLFTLFLLFIYVLGSRITLPFVDLNTKDFLGG
                     STAYLAFSAALTGGNLRSLSIFSVGLSPWMSAMILWQMFSFSKRLGLTSTSIEIQDRR
                     KMYLTLMIAVIQSLAVSLRLPVQSSYSAILVVLMNTILLIAGTFFLVWLSDLNASMGI
                     GGSIVILLSSMVLNIPQDVLETFQTVHIPTGIIVLLALLTLVFSYLLALMYRARYLVP
                     VNKIGLHNRFKRYFYLEIMLNPAGGMPYMYVMSFLSVPAYLFILLGFIFPNHSGLAAL
                     SKEFMIGKPLWVYVYISVLFLFSIIFAFVTMNGEEIADRMKKSGEYIYGIYPGADTSR
                     FINRLVLRFSVIGGLFNVVMAGGPMLFVLFDEKLLRLAMIPGLFMMFGGMIFTIRDEV
                     KALRLNETYKPLI"
     gene            13197..14777
                     /gene="asp1"
                     /locus_tag="VQ543_000567"
     CDS             13197..14777
                     /gene="asp1"
                     /locus_tag="VQ543_000567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000291149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory Sec system protein Asp1"
                     /protein_id="HET2611344.1"
                     /translation="MYYFIPAWYGSERTWHADITPWYFSHFRLEFDDTFHQIRLFQEQ
                     DIDSRLLVLAYQPHLRYFLYRHGVLETDTYSVFDVMQDFHNLHTQVLSIRDIEWDDDC
                     EFIYSPFTIIVQKNGKKFAKVEHGVEGFISDIQYFEPNGQIHMHHIMDDRGFISSIIF
                     FEDGQAAYQEYLNPKGVWQFRERLKEGGQVEVNPILGYRFKMLTYQNMGDLVAEFFEN
                     YLQTYVKDQDIFMLPSHSHHDQLVLDRLPSTNPKLLSLFIGRNPQDTFRDLDVTFEKS
                     DLILVDREDSLRLLQELYPERMHQCYHLSSFDTRLRLGRSQTKKESIIYFQLDFEQGI
                     DNQALLQVLSFVAENKDTEVIFGAFAASQEQMNEVEGIVESFIQENIQSENLGKAIDY
                     GDAENPLEENQHQDLRLQFVNLNDELDLIKTLEFVRLIVDLNRHPHLYTQIAGISAGI
                     PQINLVETVYVEHLKNGYLLTDVTEFSKAAHYYTDRLKEWNESLIYSIDKIKEHTGQQ
                     FLGKLEKWIEEVKNVKGT"
     gene            14761..16296
                     /gene="asp2"
                     /locus_tag="VQ543_000568"
     CDS             14761..16296
                     /gene="asp2"
                     /locus_tag="VQ543_000568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory Sec system protein Asp2"
                     /protein_id="HET2611345.1"
                     /translation="MSKELNILQIGLANWENHYDIPENMSWYYFYPNSSKTLREIIEK
                     EDINRFHAVLIEDGQYSRDLFSYVKYFEPYTLFYNQNLQINDREVVDFLKKRCAQAID
                     FLSPQQLINDLSKSLFGGGYGDKLFPPTIQVNPNFTGAISYQGLDYVSLEGEFGQDFA
                     QLAYWAYNIMVQKTLPIELWLEYEKEGNCDFRLVIRKMWSGSVDDFFEEVIVSEKDLE
                     QALFMDSRDGDYFLSISVEARGRGTIKLGNLHQRWSRKQFGKFVLGGNILHDSKRDEI
                     NYFFHPGDFKPPLTVYFAGYRPAEGFEGYFMMKTLGCPFILFSDPRLEGGAFYLGTDE
                     LEGKVKDTITHYLDYLGFDHKDLILSGLSMGTFPALYYGASFEPHAIIVGKPLANLGT
                     IASRGRLDAPGVSNLAFDCLIHHTGGTSSQDMTELDQRFWKIFKQANFSKTTFGLSYM
                     KDEEMDPQAYEQLVSYLCNTGAKILSKGTAGRHNDDTDTNISWFLHFYRMVLETGFGR
                     EKR"
     gene            16293..16733
                     /gene="asp3"
                     /locus_tag="VQ543_000569"
     CDS             16293..16733
                     /gene="asp3"
                     /locus_tag="VQ543_000569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory Sec system protein Asp3"
                     /protein_id="HET2611346.1"
                     /translation="MIITQRQSIYWGEVGGTYMYGTTVSYYLDKSVRLYNPLLPSGEI
                     LKTWFSSVNYQAARTQPQLPLLKRKQEYQLSLVFDCQPENGVYTKITFFDRYGDILEK
                     KVEKAKDFIFTYPEDSYTYQVSLLSAGFESLTFYHFSIKEIRSV"
     gene            16726..19098
                     /gene="secA2"
                     /locus_tag="VQ543_000570"
     CDS             16726..19098
                     /gene="secA2"
                     /locus_tag="VQ543_000570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000489793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory Sec system translocase SecA2"
                     /protein_id="HET2611347.1"
                     /translation="MFRRLGQDFQLRKVKKILKQINALKGKMSSLSDQELVAKTVEFR
                     QRLSEGESLDDILVEAFAVVREADKRILGMFPYDVQVMGAIVMHYGNVAEMNTGEGKT
                     LTATMPVYLNAFSGEGVMVVTPNEYLSKRDAEEMGQVYRFLGLTIGVPFTEDPKKEMK
                     AEEKKLIYASDIIYTTNSSLGFDYLNDNLASNEEGKFLRPFNYVIIDEIDDILLDSAQ
                     TPLIIAGSPRVQSNYYAIIDTLVTTLVEGEDYIFKEEKEEVWLTTKGAKSAENFLGID
                     NLYKEEHASFARHLVYAIRAHKLFTKDKDYIIRGNEMVLVDKGTGRLMEMTKLQGGLH
                     QAIEAKEHVKLSPETRAMASITYQSLFKMFNKISGMTGTGKVAEKEFIETYNMSVVRI
                     PTNRPRQRIDYPDNLYITLPEKVYASLEYIKQYHAKGNPLLVFVGSVEMSQLYSSLLF
                     REGIAHNVLNANNAAREAQIISESGQMGAVTVATSMAGRGTDIKLGKGVAELGGLIVI
                     GTERMESQRIDLQIRGRSGRQGDPGMSKFFVSLEDDVIKKFGPSWVHKKYKDYQVQDM
                     TQPEVLKGRKYRKLVEKAQHASDSAGRSARRQTLEYAESMNIQRDIVYKERNRLIDGS
                     RDLEDVVVDIIERYTEEVAADHYASRELLFHFIVTNISFHVKEVPDYIDVTDKTAVRS
                     FMKQVIDKELSEKKELLNQHDLYEQFLRLSLLKAIDDNWVEQVDYLQQLSMAIGGQSA
                     SQKNPIVEYYQEAYAGFEAMKEQIRADMVRNLLMGLVEVTPKGEIVTHFP"
     gene            19110..20621
                     /gene="gtfA"
                     /locus_tag="VQ543_000571"
     CDS             19110..20621
                     /gene="gtfA"
                     /locus_tag="VQ543_000571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory Sec system glycosyltransferase GtfA"
                     /protein_id="HET2611348.1"
                     /translation="MTIYNINLGIGWASSGVEYAQAYRAGVFRKLNLSSKFIFTDMIL
                     ADNIQHLTANIGFDDNQVIWLYNHFTDIKIAPTSVTVDDVLAYFGGEESHREKNGKVL
                     RVFFFDQDKFVTCYLVDENKDLVQHAEYVFKGNLIRKDYFSYTRYCSEYFAPKDNVAV
                     LYQRTFYNEDGTPVYDILMNQGKEEVYHFKDKIFYGKQAFVRAFMKSLNLNKSDLVIL
                     DRETGIGQVVFEEAQTAHLAVVVHAEHYSENATNEDYILWNNYYDYQFTNADKVDFFI
                     VSTDRQNEVLQEQFAKYTQHQPKIVTIPVGSIDSLTDSSQGRKPFSLITASRLAKEKH
                     IDWLVKAVIEAHKELPELTFDIYGSGGEDSLLREIIANHQAEDYIQLKGHAELSQIYS
                     QYEVYLTASTSEGFGLTLMEAIGSGLPLIGFDVPYGNQTFIEDGQNGYLIPSSSDHVE
                     DQIKQAYAAKICQLYQENRLEAMRAYSYQIAEGFLTKEILEKWKKTVEEVLHD"
     gene            20614..21951
                     /gene="gtfB"
                     /locus_tag="VQ543_000572"
     CDS             20614..21951
                     /gene="gtfB"
                     /locus_tag="VQ543_000572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000571772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory Sec system glycosylation chaperone
                     GtfB"
                     /protein_id="HET2611349.1"
                     /translation="MIELYDSYSQESRDLHESLVATGLSQLGVVIDADGFLPDGLLSP
                     FTYYLGYEDGKPLYFNQVPVSDFWEILGDNQSACIEDVTQERAVIHYVDGMQARLVKQ
                     VDWKDLEGRVRQVDHYNRFGACFAKTTYSADSEPIMTVYQDVNGQQVLLENHVTGDIL
                     LTLPGQSMRYFANKVEFITFFLQDLEIDTSQLIFNTLATPFLVSFHHPDKSGSDVLVW
                     QEPLYDAIPGNMQLILESDNVRTKKIIIPNKATYERALELTDEKYHDQFVHLGYHYQF
                     KRDNFLRRDALILTNSDQIEQVEAIVEALPDVTFRIAAVTEMSSKLLDMLRYPNVVLY
                     QNASPQKIQELYQLSDIYLDINHSNELLQAVRQAFEHNLLILGFNQTVHNRLYIAPEH
                     LFESSEVAALVETIKLALSDVDQMRQALGKQGQHANYVDLVRYQEIMQTVLGG"
     gene            21953..22132
                     /gene="asp4"
                     /locus_tag="VQ543_000573"
     CDS             21953..22132
                     /gene="asp4"
                     /locus_tag="VQ543_000573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001287962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory secretory system protein Asp4"
                     /protein_id="HET2611350.1"
                     /translation="MSEEDLFYKDVEGRMEELKQKPIKKEKETRGEKISKTFSLLLGL
                     MILIGLLFTLLGILR"
     gene            22137..22361
                     /locus_tag="VQ543_000574"
     CDS             22137..22361
                     /locus_tag="VQ543_000574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000571861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory secretory protein Asp5"
                     /protein_id="HET2611351.1"
                     /translation="MIEMLIVLAIILSLALIVLVTIQPRQNQLFSMDATSNIGKPSYW
                     QSNTLVKVLTLLVSLALFVLLLTFMVITYK"
     gene            22416..22496
                     /locus_tag="VQ543_000575"
                     /pseudo
     CDS             22416..22496
                     /locus_tag="VQ543_000575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(22732..23685)
                     /locus_tag="VQ543_000576"
     CDS             complement(22732..23685)
                     /locus_tag="VQ543_000576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000028179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HET2611352.1"
                     /translation="MSISQRTTKLILATCLACLFAYFLNLSSAVSAGIIALLSLSDTR
                     RSTLKLARNRLFSMLLALAIGVLAFHLSGFHIWSLGLYLAFYVPLAYKMGWEIGITPS
                     TVLVSHLLVQESTSPDLLVNEFLLFAIGTGFALLVNLYMPSREEEIQHYHTLVEEKLK
                     DILQRFKYYLSRGDGRNRAQLVAELDTLLKEALRLVYLDHSDHLFHQTDYHIHYFEMR
                     QRQSRILRNMAQQINTCHLAASESLILAQLFSKIAGQLSQTNPASDLLDEIERYLEVF
                     RNRSLPKTREEFETRATLLQLLREAKTFIQVKVDFYQKYRQ"
     gene            complement(23753..24962)
                     /gene="sstT"
                     /locus_tag="VQ543_000577"
                     /pseudo
     CDS             complement(23753..24962)
                     /gene="sstT"
                     /locus_tag="VQ543_000577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000713440.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine transporter SstT"
     gene            25101..25661
                     /locus_tag="VQ543_000578"
     CDS             25101..25661
                     /locus_tag="VQ543_000578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel"
                     /protein_id="HET2611353.1"
                     /translation="MQKFIQAYIEKLDVTTIIENILTKVISLLLLLIVFYIAKKMLHT
                     MVQRIVKPSLKMSRHDVGRQKTISRLLENVFNYTLYFFLLYCILSILGLPVSSLLAGA
                     GIAGVAIGMGAQGFLSDVINGFFILFERQLDVGDEVVLTNGPITVSGKVVSVGIRTTQ
                     LRSEEQALHFVPNRNITVVSNFSRTD"
     gene            25718..26626
                     /locus_tag="VQ543_000579"
     CDS             25718..26626
                     /locus_tag="VQ543_000579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HET2611354.1"
                     /translation="MVLEKQLGHGCTWIDLDLGKLNKLEDLSEIYGLDKETIEYALDR
                     NERAHMDYHRESGTVTFIYNVLDVKKDKAYYETFPMTFIVEHRRLITISNTKNAYVIE
                     QMTRYLESHDTLSIYKFLFASLEIISNAYYPVIEQMDKSRDEVNDLLRQRTTKKNLFA
                     LSDLETGMVYLTAAAKQNRILLEHIQGHALYRSFDEIEREQFDDAMIEAHQLVSMTDL
                     ISQILQQLSASYNNILNNNLNDNLTTLTIISVLLAVLAVVTGFFGMNVPLPLTDEPHA
                     WLYISLASAGLWIVLSLLLRKIAKKS"
     gene            26578..27168
                     /locus_tag="VQ543_000580"
     CDS             26578..27168
                     /locus_tag="VQ543_000580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqeG family HAD IIIA-type phosphatase"
                     /protein_id="HET2611355.1"
                     /translation="MDCFILVTKENCEKKLRKGARMAIENYIPDFAVEAVYDLTVPSL
                     QAQGIKAVLVDLDNTLIAWNNPDGTPEMKQWLHDLRDAGIGIIVVSNNTKKRVQRAVE
                     KFGIDYVYWALKPFTFGIDRAMKEFHYDKKEVVMVGDQLMTDIRAAHRAGIRSILVKP
                     LVQHDSIKTQINRTRERRVMRKITEKYGPITYKKGI"
     gene            27171..28277
                     /gene="yqeH"
                     /locus_tag="VQ543_000581"
     CDS             27171..28277
                     /gene="yqeH"
                     /locus_tag="VQ543_000581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000391231.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YqeH"
                     /protein_id="HET2611356.1"
                     /translation="MEEILCIGCGATIQTTDKAGLGFTPQSALEKGLETGEVYCQRCF
                     RLRHYNEITDVQLTNDDFLKLLHEVGDSDALVVNVIDIFDFNGSVIPGLPRFVSGNDV
                     LLVGNKKDILPKSVKSGKISQWLMKRAHEEGLRPVDVVLTSAQNKHAIKEVIDKIEHY
                     RKGRDVYVVGVTNVGKSTLINAIIQEITGDQNVITTSRFPGTTLDKIEIPLDDGSYIY
                     DTPGIIHRHQMAHYLTAKNLKYVSPKKEIKPKTYQLNPEQTLFLGGLGRFDFIAGEKQ
                     GFTAFFDNELKLHRSKLEGASAFYDKHLGTLLTPPNSKEKEDFPRLVQHVFTIKDKTD
                     LVISGLGWIRVTGTAKVAVWAPEGVAVATRKAII"
     gene            28491..28802
                     /gene="yhbY"
                     /locus_tag="VQ543_000582"
     CDS             28491..28802
                     /gene="yhbY"
                     /locus_tag="VQ543_000582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000060164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome assembly RNA-binding protein YhbY"
                     /protein_id="HET2611357.1"
                     /translation="MSLASKQRAFLNSQAHTLKPIIQIGKNGLNDQIKTSVRQALDAR
                     ELIKVTLLQNTDENIHEVAEILEEEIGVDTVQKIGRILILFKQSSKKENRKISKKVKE
                     I"
     gene            28854..29483
                     /locus_tag="VQ543_000583"
     CDS             28854..29483
                     /locus_tag="VQ543_000583"
                     /EC_number="2.7.7.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide adenylyltransferase"
                     /protein_id="HET2611358.1"
                     /translation="MTIELLTPFTKVELEPEIKEKKRKQVGILGGNFNPVHNAHLIVA
                     DQVRQQLGLDQVLLMPEYQPPHVDKKETIPEHHRLKMLELAIEGIDGLVIETIELERK
                     GISYTYDTMKILTEKNPDTDYYFIIGADMVDYLPKWYRIDELVDMVQFVGVQRPRYKV
                     GTSYPVIWVDVPLMDISSSMVRDFLAQGRKPNFLLPQPVLDYIEKEGLY"
     gene            29483..30076
                     /gene="yqeK"
                     /locus_tag="VQ543_000584"
     CDS             29483..30076
                     /gene="yqeK"
                     /locus_tag="VQ543_000584"
                     /EC_number="3.6.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bis(5'-nucleosyl)-tetraphosphatase (symmetrical)
                     YqeK"
                     /protein_id="HET2611359.1"
                     /translation="MSYQDYINCSREALLEKMAEFLPEKRLTHCLGVERAAMELAQRF
                     GVDVEKASLAGLLHDYAKKLSNQEFLALIDRYQLDPDLKNWGNNVWHGMVGIYKIQED
                     LDLHDSEILRAIEVHTVGAGQMTDLDKVIYVADYIEHNRAFPGVDVAREIANLSLNKA
                     VAYETARTVEYLAHQGFPIYPQTLETYNAFVHYLKEN"
     gene            30077..30577
                     /locus_tag="VQ543_000585"
     CDS             30077..30577
                     /locus_tag="VQ543_000585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000844697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HET2611360.1"
                     /translation="MKTAFIIIDVQNILVETGFQTKSLLGKISYLQNQARSKNIEIIY
                     VQHIENSEAQTSEDWQLSALLNRKPAEKVFQKKYNSIFKETGLKEYLDKQGIEKLVLC
                     GMQTEYCVDTSVKVAFEYGYQLIVPEGAVTTFDGDDIPAETINEFYEDIWEERFADVL
                     DYKHIF"
     gene            30590..30943
                     /gene="rsfS"
                     /locus_tag="VQ543_000586"
     CDS             30590..30943
                     /gene="rsfS"
                     /locus_tag="VQ543_000586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001003018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome silencing factor"
                     /protein_id="HET2611361.1"
                     /translation="MNEKELLELVVKAADEKRAEDILALDVQDLTSVTDYFVITSSMN
                     SRQLDAIAANIREKVAQAGFKGSHVEGDAAGGWVLLDLGAVVVHIFSEEMRAHYNLEK
                     LWHEANSVDISEALA"
     gene            31263..32003
                     /locus_tag="VQ543_000587"
     CDS             31263..32003
                     /locus_tag="VQ543_000587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001823113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HET2611362.1"
                     /translation="MATYETFAAVYDAVMDDSLYDKWTNFSLRHLPKTKERKKLLELA
                     CGTGIQSVRFSQAGFDVTGLDLSADMLKIAEKRATSAKQKIAFIEGNMLNLSKAGKYD
                     FVTCYSDSICYMQDEVEVGDVFKDVYNALNEEGVFIFDVHSTYQTDEVFPGYSYHENA
                     EDFAMLWDTYEDEVPHSIVHELTFFIKEADGSFSRHDEVHEERTYEILTYDILLEQAG
                     FKSFKLYADFEDKEPTETSTRWFFVAQK"
     gene            32013..33110
                     /locus_tag="VQ543_000588"
     CDS             32013..33110
                     /locus_tag="VQ543_000588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000156376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HET2611363.1"
                     /translation="MTITGIIAEFNPFHNGHKYLLDQAEGLKIVAMSGNFMQRGEPAI
                     VDKWTRAQMALENGADLVVELPFLVSVQAADFFGQGAVDILDRLGIDSLVFGTEEVLD
                     YQKIADLYTEKGAEMEKFVKNLPDSLSYPQKTQAMWKEFAGLDFSGNTPNHVLALAYA
                     KAVAGRNIKLHPIQRQGAGYHSVNKDVDFASATALRQHQKDQDFLERFMPSVALFEQA
                     SKVIWEDYFPLLRYQILSNPDLTTIYQVNQEMAVRIKEAIKTAQSVEELVELVTTKRY
                     TKARVRRLLTYILVQARENVLPEAIHVLGFTEKVRQHLKSLKGQVNLVSRIGKEPWDA
                     MTQKADQIYQLGKPSIAEQNFGRVPIRIETN"
     gene            33348..33602
                     /locus_tag="VQ543_000589"
     CDS             33348..33602
                     /locus_tag="VQ543_000589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000388574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HET2611364.1"
                     /translation="MEAVLYSTFRNHLKDYMKKVNDEFEPLTVVNKNPDEDIVVLSKS
                     EWDSIQETLRIAQNKELSDKVLRGMAQVRAGSTQVHVIEE"
     gene            33606..33860
                     /locus_tag="VQ543_000590"
                     /pseudo
     CDS             33606..33860
                     /locus_tag="VQ543_000590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006152757.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
     gene            34051..35664
                     /locus_tag="VQ543_000591"
     CDS             34051..35664
                     /locus_tag="VQ543_000591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Y"
                     /protein_id="HET2611365.1"
                     /translation="MEIMSLAIAVFAVIIGLVIGYVSISAKMKSSQEAAELMLLNAEQ
                     EATNLRGQAEREADLLVNEAKRESKSLKKEALLEAKEEARKYREEVDAEFKSERQELK
                     QIESRLTERATSLDRKDDNLTSKEQTLEQKEQSISDRAKNLDAREEQLEEVERQKEAE
                     LERIGALSQAEARDIILAQTEENLTREIASRIREAEQEVKERSDKMAKDILVQAMQRI
                     AGEYVAESTNSTVHLPDDTMKGRIIGREGRNIRTFESLTGVDVIIDDTPEVVTLSGFD
                     PIRREIARMTMEMLLKDGRIHPARIEELVEKNRQEIDNKIREYGEAAAYEIGAPNLHP
                     DLMKIMGRLQFRTSYGQNVLRHSIEVAKLAGIMASELGENAALARRAGFLHDIGKAID
                     HEVEGSHVEIGMELARKYKEPPVVVNTIASHHGDVEAESVIAVIVAAADALSAARPGA
                     RSESLESYIKRLHDLEEIANGFEGVQTSFALQAGREIRIMVNPGKIKDDKVTILAHKV
                     RKKIENNLDYPGNIKVTVIRELRAVDYAK"
     gene            35794..36420
                     /gene="gmk"
                     /locus_tag="VQ543_000592"
     CDS             35794..36420
                     /gene="gmk"
                     /locus_tag="VQ543_000592"
                     /EC_number="2.7.4.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000775037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HET2611366.1"
                     /translation="MADRGLLIVFSGPSGVGKGTVRREIFESSENQFQYSVSMTTRAQ
                     RPGEVDGVDYFFRTREEFEELIRQGQMLEYAEYVGNYYGTPLTYVNETLDKGIDVFLE
                     IEVQGALQVKKKVPDAVFIFLTPPDLDELQDRLVGRGTDSAEVIAQRIEKAKEEIALM
                     REYDYAIVNDQVPLAAERVKCVIEAEHFCVDRVIGHYQEMLPKSPTTR"
     gene            36445..36759
                     /locus_tag="VQ543_000593"
     CDS             36445..36759
                     /locus_tag="VQ543_000593"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001817694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HET2611367.1"
                     /translation="MMLKPSIDTLLDKVPSKYSLVILEAKRAHELEAGAPATQGFKSE
                     KSTLRALEEIESGNVTIHPDPEGKREAVRRRIEEEKRRKEEEEKKIKEQIAKEKEDGE
                     KI"
     gene            36825..39221
                     /locus_tag="VQ543_000594"
     CDS             36825..39221
                     /locus_tag="VQ543_000594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001162119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein N'"
                     /protein_id="HET2611368.1"
                     /translation="MALAKIIVDVPLMQTDQPYSYRIPEEFEGMLEVGMRVHVPFGKG
                     NRLIQGIVLGLKSQSDGEEMEQDLKDIAEVLDFSPVLTPEQLWLAEELRKSVFSYKIS
                     ILKAMLPGFLNSSYDKILYPLEGLSQEERVRLFGSEDSLAFSSLDLAKQAEMMRLTRK
                     GLLGLEYQAVDQKKVKTQSWYEVDHAQLEGVEISTRAKKKLELRDYLLSHPESASLAS
                     LLESYSREQVNFFVDQGTVTIVQKEVQRSAAYFEGIEASRPLELNPEQRQARDAVVSS
                     IGSSQPPFLLQGITGSGKTEVYLQIIQGALDKGKTAILLVPEISLTPQMTERFIARFG
                     DKVAILHSGLSNGEKYDEWRKVERGDAQVVVGARSAIFAPLKNLGVMIIDEEHEAAYK
                     QDSNPRYHAREVAILRAQYNQATLVLGSATPSLESRARAGKGVYQHLRLTQRANPLAT
                     IPEVQVIDFRDYIGQNETSNFTPPLLEAIQDRLVKKEQVVLMLNRRGYSSFVMCRECG
                     TVDTCPNCDISLTLHMDTKTMNCHYCGFSKDIPQVCPNCKSRSIRYYGTGTQKAYDEL
                     AELFPQARILRMDVDTTRKKGSHQALLDQFGRGEADILLGTQMIAKGLDFPNVTLVGV
                     LNADTALNLPDFRSSERTFQLLTQVAGRAGRAEKAGQVLIQSYNSQHYAIRFAKDQDY
                     EGFYAYEMGIRRQLGYPPYYFTIGITLSHKKEEEVFKRAYEVMNILRSGLSETSPILG
                     PTPKPIARTHNLYHYQILIKYRLEDELGPTLNQVLALTQERENSELRLSIDHEPQQFL
                     "
     gene            39234..40169
                     /locus_tag="VQ543_000595"
     CDS             39234..40169
                     /locus_tag="VQ543_000595"
                     /EC_number="2.1.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl-tRNA formyltransferase"
                     /protein_id="HET2611369.1"
                     /translation="MTKLIFMGTPDFSATVLKGLLTDDRYEILAVVTQPDRAVGRKKV
                     IQETPVKQAAKEAGLSIYQPEKLSGSPEMEELMKLGADGIVTAAFGQFLPSKLLDSMD
                     FAVNVHASLLPRHRGGAPIHYALIQGDEEAGVTIMEMVKEMDAGDMISRRSIPITDED
                     NVGTLFEKLALVGRDLLLDTLPAYIAGDIKPEPQDTSQVTFSPNIKPEEEKLDWNKTN
                     RQLFNQIRGMNPWPVAHTFLKGDRFKIYEALPVEGQGNPGEILSIGKKELIVATAEGA
                     LSLKQVQPAGKPKMDIASFLNGVGRTLTVGERFGD"
     gene            40162..41475
                     /gene="rsmB"
                     /locus_tag="VQ543_000596"
     CDS             40162..41475
                     /gene="rsmB"
                     /locus_tag="VQ543_000596"
                     /EC_number="2.1.1.176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(967)-C(5))-methyltransferase
                     RsmB"
                     /protein_id="HET2611370.1"
                     /translation="MTKVETARSLALAVLEDVFVNQAYSNIALNKHLKGSQLSAADKG
                     LVTELVYGTVARKLTLEWYLSHFIEDRDQLDSWLYVLLLMSAYQLRYLDKIPDHAVVN
                     EAVELAKLRKKGSEKLVNAVLRRILREGWPDIASIKRKNKRDSIAYSLPVWLVAKLKE
                     EYGEERAKAIFESLLVRNKASIRVTDLSRKEEIQALLEANNSLLATTGLVKEQGHFAG
                     HNLFADGAITIQDESSQLVAPTLDLQGDERVLDACAAPGGKTAHIASYLTTGQVTALD
                     LYDHKLDLIQENAQRLGVEDRVQTQKLDARKVHEFFDQDSFDKILVDAPCSGIGLLRR
                     KPDIKYNKETADFASLQEIQLEILGSVCQILGKGGIITYSTCTIVSEENFQVVKAFLE
                     SHPEFEQVKLEHECKDIMKDGCILITPELYGSDGFFISQFRKISD"
     gene            41490..42230
                     /locus_tag="VQ543_000597"
     CDS             41490..42230
                     /locus_tag="VQ543_000597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stp1/IreP family PP2C-type Ser/Thr phosphatase"
                     /protein_id="HET2611371.1"
                     /translation="MEISLLTDVGQKRTNNQDYVNHYVNRAGRTMIILADGMGGHRAG
                     NIASEMAVTDLGVAWVDTQIDTVNEVREWFAHYLEIENQKIHQLGQDEAYRGMGTTLE
                     VLAIIDNQAIYAHIGDSRIGLIRGEEYHQLTSDHSLVNELLKAGQLTPEEAEAHPQKN
                     IITQSIGQKDEIQPDFGTVILESGDYLLLNSDGLTNMISGSEIRDIVTSDIPLADKTE
                     TLVRFANNAGGLDNITVALVFMNEEDAE"
     gene            42227..44206
                     /gene="pknB"
                     /locus_tag="VQ543_000598"
     CDS             42227..44206
                     /gene="pknB"
                     /locus_tag="VQ543_000598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stk1 family PASTA domain-containing Ser/Thr
                     kinase"
                     /protein_id="HET2611372.1"
                     /translation="MIQIGKIFAGRYRIVKQIGRGGMADVYLAKDLILDGEEVAVKVL
                     RTNYQTDPIAVARFQREARAMADLDHPHIVRITDIGEEDGQQYLAMEYVAGLDLKRYI
                     KEHYPLSNEEAVRIMGQILLAMRLAHTRGIVHRDLKPQNILLTPDGTAKVTDFGIAVA
                     FAETSLTQTNSMLGSVHYLSPEQARGSKATVQSDIYAMGIIFYEMLTGHIPYDGDSAV
                     TIALQHFQKPLPSVIAENPSVPQALENVIIKATAKKLTNRYRSVSEMYVDLSSSLSYN
                     RRNESKLIFDETSKADTKTLPKVSQSTLTSIPKVQAQTEHKSIKNPSQAVTEETYQPQ
                     APKKHRFKMRYLILLASLVLVAASLIWILSRTPATIAIPDVAGQTVAEAKATLKKANF
                     EIGEEKTEASEKVEEGRIIRTDPGAGTGRKEGTKINLVVSSGKQSFQISNYVGRKSSD
                     VIAELKEKKVPDNLIKIEEEESNESEAGTVLKQSLPEGTTYDLSKATQIVLTVAKKAT
                     TIQLGNYIGRNSTEVISELKQKKVPENLIKIEEEESSESEPGTIMKQSPGAGTTYDVS
                     KPTQIVLTVAKKVTSVAMPSYIGSSLEFTKNNLIQIVGIKEANIEVVEVTTAPAGSVE
                     GMVVEQSPRAGEKVDLNKTRVKISIYKPKTTSATP"
     gene            44321..45079
                     /locus_tag="VQ543_000599"
     CDS             44321..45079
                     /locus_tag="VQ543_000599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HET2611373.1"
                     /translation="MEESKELNAVIDVIMLAGTILLKSGSEIHRVEDTMIRIAHSQGI
                     VDCNVLAMPAAIFFSIENTNISRMKRVTSSSYNIEKVCDVNQISRQLVGGQIDLETAF
                     KQLTALQAQPLPYTKLQVTLAATFSAPFFSVMFSGNIYDALGAGVATLFGFAFSLYVE
                     KFIRIPFVTAFAGAFVFGIIAQFWARYTGFPSTADLIIAGAVMPFVPGIALTNAVRDI
                     MTNHINSGMSKMFESLLITLALGAGTSVALVLMN"
     gene            45081..45530
                     /locus_tag="VQ543_000600"
     CDS             45081..45530
                     /locus_tag="VQ543_000600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HET2611374.1"
                     /translation="MTLTTFLLQAVASFLAIITFLIVLNVQRSMLLPGGILGMTVWLI
                     YLLLKEPTNVIVATFIAAIIGSCVSQILSILYKTPAVVFILAILAPLVPGYLSYRTTA
                     FFVTGDYNKALASATLVVMLALVISIGMASGTVILRLYHYIKTHRVS"
     gene            45592..45807
                     /locus_tag="VQ543_000601"
                     /pseudo
     CDS             45592..45807
                     /locus_tag="VQ543_000601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
BASE COUNT        13956 a         8211 c        10289 g        13351 t
ORIGIN      
        1 tcaaccagtg cgtcagcttc cgcatcaacg agtgcgtctg aatcggcatc aacctcagca
       61 agtacaagtg catcggcttc agcaagcacc agtgcttcgg cttcagcaag cacgtcagca
      121 tcaacaagca caagtacatc ggcaagcacg tcagcatcga caagtgcaag cacatcggcg
      181 tcaacaagtg caagtacgtc agcatctgaa tcggcctcaa ccagtgcgtc gacttcagca
      241 agtacaagcg cctcagcctc agcaagtatc tcagcgtctg aatcggcatc aaccagcgcc
      301 tcagcctcag catcaacaag tgcatcagct tcagcaagca cctcagcgtc tgaatcggca
      361 tcaacgagtg cctcagcttc agcaagcacc agtacctcag cttctgaatc ggcctcaacc
      421 agtgcctcag cttcagcgtc aaccagtgcc tcagcttctg catcaaccag cgcctcggcc
      481 tcagcaagca cctcagcatc tgaatccgca tcaacgagta cctcagcttc tgaatcggcc
      541 tcaacaagtg cctcggcctc agcaagcaca agcgcctcag cttcagcaag taccagtgcg
      601 tcagcttccg catcaacgag tgcttcggct tcagcctcaa cgagtgcctc agcttcagcg
      661 tcaaccagtg cttcagcctc agcatcaacg agtgcttcgg cttcagcaag taccagtgct
      721 tcggcctcag catcgacaag tgcctcagct tcagcaagta ctagcgcctc agcctcagca
      781 tcaaccagtg cctcggcttc agcaagtact agcgcctcag cttcagcgtc aaccagtgcc
      841 tcagcatcag caagcacctc agcgtctgaa tcggcatcaa ccagtgcgtc tgagtcagca
      901 tcaacgagtg cgtcagcctc agcaagtaca tcagtttcaa attcagcaaa ccattcgaac
      961 tcacaagttg gaaatgcttc tggatcgaca ggtaaatccc aaaaagaatt gcctaataca
     1021 ggtactgagt cgtcaattgg atctgtgtta cttggagttc tagcagctgt tacaggtatt
     1081 ggattggttg cgaaacgccg taaacgtgat gaagaagagt aagacaacct gtaaagttag
     1141 gctaaactaa ctcgcgcaca taaatcaagg agaaaattgc tagtggatga taaaattacg
     1201 gtcattgtac cagtatacaa tgtagaaaac tatctgagga aatgtctaga tagtattatt
     1261 tctcaaacat ataaaaatat tgagattgtt gtcgttaatg atggttctac ggatgcttca
     1321 ggtgaaattt gtaaagaatt ttcagaaatg gatcaccgaa ttctctatat agaacaagaa
     1381 aatgctggta tttctgccgc acgaaacacc ggtctgaata atatgtccgg aaattatgtg
     1441 acctttgtgg attcagatga ttggattgag ttagattatg tagaaaccct atataaaaaa
     1501 ataacagaat atcaagctga tattgcagtt gggaattact attctttcaa cgaaagtgaa
     1561 ggaatgttct actttcatat atcaggagac tcctattatg ataaggtata tgacaatgtt
     1621 tccatctttg agaacttgtt atgaaactca agaaatgaag agttttgctt tgatatctgc
     1681 ttgtggtaaa ctctataagg caagattgtt tgagcagttg cgctttgaca tgggtaaatt
     1741 aggagaagat ggttacctca atcaaaaggt atatttatta tcggaaaagg taatttattt
     1801 aaataaaggt ctttatgctt atcggattag aaaaggtagt ctatcaagag tttggacaga
     1861 aaagtggatg cacgccttag ttgatgctat gtctgaacgt attacgctac tagctaatat
     1921 gggatatcct ctagagaaac acttggcagt ttatcgtcag atgttggaag tcagtctcgc
     1981 caacggtcaa gctagtggtt tatctgacac agcaatatat aaagagtttg aaatgaaaaa
     2041 aagactttta aatcagttaa cggtacaaga atcaagtgaa aagaaagcca ttgtcctagc
     2101 agcaaactat ggctatgtag accaagtttt aacgacaatc aagtctattt gttatcataa
     2161 tcgttcgatt cgtttttatc tgattcatag cgattttcca aatgaatgga ttaagcaatt
     2221 aaataagcgc ttagagaagt ttgactcaga aattattaat tgtcgggtaa cttctgagca
     2281 aatttcatgt tataaaacgg atattagtta cacagttttt ttacgctatt tcatagctga
     2341 tttcgtgcaa gaagataagg ccctctactt ggactgtgat ttacttgtaa cgaaaaatct
     2401 tgatgatttg tttgctacag acttacaaga ttatcctttg gctgctgtta gagattttgg
     2461 gggcagagct tattttggtc aagaaatctt taatgccggt gttctcttgg taaacaatgc
     2521 tttttggaaa aaagagaata tgacccaaaa attaattgat gtaaccaatg aatggcatga
     2581 taaggtggat caggcagatc agagcatctt gaatatgctt tttgaacata aatggttgga
     2641 attggacttt gattataatc atattgtcat tcataaacag tttgctgatt atcaattgcc
     2701 tgagggtcag gattatcctg ctattattca ctatctttct catcggaaac cgtggaaaga
     2761 tttggcggcc caaacctatc gtgaagtttg gtggtactat catgggcttg aatggacaga
     2821 attgggacaa aaccatcatt tacatccatt acaaagatct cacatctatc caataaagga
     2881 acctttcact tgtctaatct atactgcctc agaccatatt gaacaaattg agacattggt
     2941 tcaatccttg cctgatattc agtttaagat agcagctaga gtaatagtta gtgatcgatt
     3001 ggctcagatg acaatttatc caaacgtgac tatatttaac ggaattcact atttggtaga
     3061 tgtcgataat gaattggtag aaaccagtca agtactttta gatattaatc atggtgaaaa
     3121 aacagaggaa attatcaatc aatttgcaag acttggaaaa actattttgt cctttgaaaa
     3181 taccaaaacc tatgaagcag gtcaggaggt atatgctgtt gaccaagttc aagcaatgat
     3241 tgagaaattg agagaaataa gcaaatgaag aaaaatcatt tagtaggaga tgctctgatt
     3301 ttgactgtta gtgatcagat tgaagagttg gattatctcc ttgaatcctt gccaaatatc
     3361 tgtttttata ttgcagcacc tgttcaattt tccgagaaaa tccgtagctt agaaacgaac
     3421 tataatgtcc gtctccgaac gattacaaat gaagaacagc taaactttct agtcgatacc
     3481 tgtgactttt tactagatat caatcacttt caagaagtag atgctattgt ctccaagttt
     3541 gtacaggctg gaaaatctgt ctttgctttt gacaatacag tccatggaaa tcaggggcag
     3601 gaagtttttc tatcaagtac accagacaaa ttggtttcta gagtgagaga ctatctgaat
     3661 gaagtcagag taggcaccaa tcatcaagaa aaaatcatcc aagatgggac ttggaatgtc
     3721 tttaaaatcg atgataaggc tcacttcatt gtaggagcaa atgtcatctg cagaaatttt
     3781 gaaaattttc atgtctcttc tggtaagtta atactgcatg atggtgtttt tatcaacaac
     3841 tcttgtagtt ttaactgtat ggaaagaatt gaaatcggag ctggtaccat gatgggagag
     3901 ggtgttcgtt tttatgatca cgaccatatt tatactgctg aaaagattga aaagtggcag
     3961 tggactacag cgccgattag agttggcaga gactgctgga taggaagtaa tgtcacgatt
     4021 ttaaaaggag tgacgattgg ggataatacc attattggag caggttgtct catacgcaat
     4081 gatattccat caaacagtgt agtttataat aatggaaatc ttgttgtaaa gagaagagat
     4141 taagagggaa atagaataaa tcaagtctag gaaagttagt atatggaaaa tgaactaatt
     4201 agtattgtag tcccaatcta caacgttgag aattatttgc gacagtgttt ggatagtatt
     4261 caaaaacaaa cttatccgaa ttttgaatgt atcatggtta atgatggctc tccagatcat
     4321 tcatccaaaa tatgtgaaga atttgtagag aaagattctc gtttcaaata ttttgagaaa
     4381 gcaaacggcg gtctttcatc agctcgtaac ctaggtattg aatgttcggg ggggggcgta
     4441 cattactttt gtagactctg atgattggtt ggaacatgat gctttagacc gattatatgg
     4501 tgctttgaaa aaggaaaacg cagatattag tatcgggcgt tataattctt atgatgaaac
     4561 acgctatgtg tatatgactt atgttacgga tccagatgat tctctggaag tgatagaagg
     4621 taaagcaatc atggataggg aaggtgtcga agaagtcaga aatgggaact ggactgtagc
     4681 tgtcttgaag ttattcaaga gagagttact acaagattta ccatttccta taggaaaaat
     4741 tgcagaggat acttactgga catggaaggt acttctaaga gcttcgagga tagtctattt
     4801 gaatcgttgt gtttactggt accgtgttgg tttatctgat actttatcga atacatggag
     4861 tgaaaagcgt atgtatgatg aaatcggggc tagggaagaa aagatagcta ttttagcaag
     4921 ttcagactat gacttgacca atcatatttt gatttataaa aatagattac aaagagtgat
     4981 agcaaaatta gaagaacaaa atatgcagtt cacagagatt tatagaagaa tgatggaaaa
     5041 attgtcttta cttccgtaga tagtaataaa aaatgagata gcgtaatatg aaactacatt
     5101 taacaaattt atacggcatg gctggtgata gtacggttat cttagctcaa aatgctgttc
     5161 aaaagatagc tagtcaactg ggatttagag aggttggtat ttatttttac aacattgctt
     5221 cagatagtcc ttctgaaatg aataagcgtc tggatggtat tatggccagt atttctattg
     5281 gggatatttt agtctttcag tctccaacct ggaatggctt tgaatttgat cgtctcttgt
     5341 ttgataagtt gaaggatatg caggtgaaaa ttatttgctt tatccatgat gttgttcccc
     5401 tcatgtttga tagtaactat tatctcatga aagactatat gtacatgtat aatctatcag
     5461 atgttttgat agtgccgtca gagagaatga aaacacgcct gatggaagaa ggattgacga
     5521 ctaagaagat tcttgttcaa gggatgtggg atcatcctca tgatttatcc ttatacaccc
     5581 ctgcttttaa aaaagaactt ttttttgctg gaagtttaga gcgttttcca gacttacaaa
     5641 attggtctca agatacgcct ttgagagtat tttcaaataa aggggaagct agttctagtg
     5701 ctagaaatct cagcatcgaa ggatggaaaa aagatgagga attgttgcta gaattatcaa
     5761 agggtggatt tggccttgtc tggggaactt atcaaaacga tggagaaagc aaccaatatt
     5821 ataccttaaa tatatctcat aaggtgagta cctatctgac agcgggcatc ccagtcattg
     5881 taccaagtag cttgtcaact gctaaattta tagtagatca aggcttaggc tttgtggcga
     5941 atagtctaga agaagttcat gcgatagttg ataaaatgaa tctacaagaa tatcaagaaa
     6001 tgacgaatcg gataaaaacc tttagttatt tgctaaaaga aggttatttt actaaaaaat
     6061 tattggtaga tgcaatttac catttgggag ttgaataaga gaacaagatg attaaaacaa
     6121 ttgtattagc tggtgatcgt aattacatca ggcagttaga aacaaccata aaatctattt
     6181 tataccacaa tcgagatgtt aagatttata ttttaaatca agatattatg ccagattggt
     6241 ttcgcaaacc acgaaaaata gctcgcatgt taggtagtga gattatcgat gtgaagctac
     6301 ctgaacaaac tgtgtttcaa gattgggaaa agcaagatca cattagtagc attacctata
     6361 ctagatattt tattgcagat tatatccaag aagataaggt tttatattta gacagtgatt
     6421 tgattgtaaa tacttcttta gagaaattat ttagtatttg tttagaagaa aaatcactcg
     6481 cagcagttaa agatacagat ggaattacat ttaatgcagg tgttttatta atcaacaata
     6541 aaaaatggcg tcaagagaaa ttaaaagaac gactaattga acagagcatt gttacaatga
     6601 aggaagttga agaaggccgt ttcgagcatt ttaatggtga tcaaacgatt tttaatcagg
     6661 tcttacaaga tgattggtta gagctggata aagaatttaa ccttcaagtg ggtcatgatg
     6721 taactgcttt ttataataaa tgggaaaatt attttaatga gttagtacct cctagtatta
     6781 ttcattttgt gtcttacaga aaaccctgga ccaccttgat agccaatcgt tatcgtgatt
     6841 tatggtggga atttcatgat ttggaatgga ctaaaatttt acaacatcat ataggggagt
     6901 ttgaactgac atcgtcttta gataaggaat tttcttgttt aactttgaca aattcccaag
     6961 atttagaagg aatagaagag ttagtcacag ctttaccaga tgtggtattt catattgctg
     7021 cttggacgga tatgggtgat aagctgataa aattagctgt gtatgataat gtgagattgc
     7081 atccacaaat tgttcctcct gtattagata agctgaaaaa gtcaacaaat ctatatttgg
     7141 atatcaatca tggtagtgca gatgagaact ttttaaaatc tttgcaagaa caagaaaaaa
     7201 cgctactagc ttttcaatcg actcagcacg gagagttagg acaaatcgtt ttcgaaaatg
     7261 ggaaagtttc ctttatgatt gatacgatta aagattttaa gaaaaacgga catcttacct
     7321 gttttcgaca acttccaagt ttaacttgtt taacgtttac ggcttctcag gatatcgaac
     7381 aattggatta cttggctgga cagttgccaa atgttgtttt tcaagttgct gcttggacag
     7441 ctatggggcc aaaattatat gatttgtcta atcgttatcc taatattcag ctctatccgg
     7501 caatttctag agataagcta gacgagttga aggagaagat ggatgcttat ttagatatca
     7561 acctactgac ttcaacatcc gatatcgttg cagaaatggc tcatctatct aaacctatac
     7621 tagcctttta taaatctcaa aatgggaata atggccaaag gttgtattca agtgaacatc
     7681 ctgaacgaat gttggctgat ttgcaaaaat tgataactaa ggatatgcta gaaaaaccgc
     7741 ttgatataat ccaggtgaaa gggatagatg aaaccttgga ttatattatt gaacacaact
     7801 cttctttagt tcgttttgga gatggggaaa tcaatatgct tgcagggcat tcaattccct
     7861 accaggatta tgatgaagag ttggtttcaa tcatgaggga cattatcggc caagaaagtc
     7921 gagaagattt agtagtgtgc cttcctgatg cttttacaga tcgttttagg tttacatcgt
     7981 gggcgattcc attttggaaa gatcacatgg atcattatat ggatttttac agagagttat
     8041 gcagtgattc atggtatggc tcaacctttg tatctcgccc ttatatcgat tttgaagaca
     8101 agagtcaagc taaagctcaa tttgaaaaat tgaaaagcat ttgggaaaac cgtgacttac
     8161 tgatagtcga aggtgcgact tctcgttcag gtgtcggaaa tgatttattc gatgaggcaa
     8221 attctattaa gcgaattatc tgtccttctc atagtgcctt ttctagagtt catgaaattg
     8281 aacaagaaat tgaaaagtat gctggtggtc gcttgatttt atgtatgctg ggtcctacag
     8341 caaaagttct gagttataat ctatgccaga tgggctatca agttttggat gtaggccata
     8401 ttgactcaga gtatgaatgg atgaaaatgg gagctaaaac taaggttaaa ttttctcata
     8461 aacatactgc agagtataat tttgatcaag atattgaatt tattgatgat gaaacctata
     8521 acagtcagat tgttgcacga atattaaact agactattta aaataaatga taaggattta
     8581 aaatgagaaa taccaaacgc gctgtagcat ttgcaggtga ttacgcttat attcgacaaa
     8641 tcgaaacggc gatgaagtca ctctgtagac acaatagtca tttgaaaatt tatctgctaa
     8701 atcaggacat tcctcaggaa tggtttagtc aaataagaat atatttacaa gagatggggg
     8761 gcgacttgat tgactgcaag ttaattggct cacagtttca aatgaattgg tctaataaat
     8821 tacctcatat caatcatatg acatttgcac gctattttat tccagatttt gtaacagaag
     8881 ataaagttct ctatctagat agtgatttga ttgtgactgg tgatttgacc gatttgtttg
     8941 aattagactt aggtgaaaat tatttggcag cagctcgttc ttgctttgga gcaggagtcg
     9001 gcttcaatgc tggtgttctc ttgattaaca acaaaaaatg gggatctgaa actattcgac
     9061 aaaaattgat tgacttaaca gaaaaagaac atgagaatgt ggaagaagga gaccagtcaa
     9121 ttttgaatat gttgtttaaa gatcaatata gttcccttga agatcaatat aattttcaaa
     9181 taggatatga ttatggggcg gcagccttta aacatcaatt catttttgat attccgctcg
     9241 aaccactgcc actaatttta cactatattt ctcaggataa gccttggaat caattttctg
     9301 ttggacgtct aagagaagtt tggtgggaat actctttgat ggattggtct gttattttaa
     9361 atgaatggtt ttcaaagagt gtgaagtatc ctagtaaatc acaaatattt aagttacaat
     9421 gtgttaattt aacgaattct tggtgtgtcg agaaaatcga ttatttggcg gagcaattgc
     9481 cagaagttca ttttcatatt gttgcttata caaatatggc aaatgaacta ctagctttaa
     9541 cgcgttttcc taatgttacc gtatatccaa attccttacc aatgttattg gaacaaatag
     9601 taatagcttc agatttgtat ttggatttga atcatgatcg aaaattagaa gatgcatatg
     9661 agtttgtgct taagtacaaa aaaccaatga tagctttcga caatacttgc tctgaaaatc
     9721 tttctgagat ttcatatgaa ggtatctatc caagctccat tccgaaaaaa atggttgcag
     9781 caatcagatc ttacatgagg tagagaacag tatgagaaaa tcaatagtat tagcggcaga
     9841 taatgcctat cttattcctt tagagacgac tataaagtct gtattgtatc acaatagaga
     9901 tgttgatttt tatattctca acagtgatat agctcctgaa tggtttaaat tattggggag
     9961 aaaaatggaa gttgtgaatt ctacaattcg cagtgtacac attgataaag aactttttga
    10021 aagctataaa acaggacctc atataaatta tgcttcttac tttagatttt ttgcgacaga
    10081 agtggttgaa tctgataggg tattgtatct ggattccgat atcattgtaa ctggggaact
    10141 agctactttg tttgagatag atctcaaagg atattcaatt ggtgctgttg atgatgtcta
    10201 tgcctatgaa ggacgaaaat ctggatttaa tgctggtatg ttactaatgg atgttgcaaa
    10261 atggaaagaa cactctattg tcaatagttt attggaatta gcggccgagc aaaatcaagt
    10321 tgttcatctt ggggatcaga gtattttaaa tatttatttt gaggataatt ggctagcctt
    10381 agataaaaca tataattata tggtgggtgt tgatatttat caccttgctc aagaatgtga
    10441 acgtctagat gacaatccac ctacaattgt tcactatgct agtcatgata aaccttggaa
    10501 tacatatagt atatctagac tacgtgaatt atggtgggtt tatagagatt tggattggtc
    10561 agagattgct tttcaacgtt ccgatttaaa ttattttgaa agaagcaatc agtctaaaaa
    10621 acaagtgatg cttgtgacat ggagtgcaga tataaaacat ttagagtatt tagtacaacg
    10681 gttacctgat tggcattttc atttggctgc accgtgtgat tgttctgagg agctgacctc
    10741 tctatcacag tatacgaatg taacagtata tcaaaatgta ttacatagta gaattgattg
    10801 gctattggac gattctatag tttatttaga tattaataca ggtggagagg tttttaatgt
    10861 agttacaagg gcacaagaaa gtggcaagaa aatcttcgct tttgatatca cacgtaaaag
    10921 tatggatgat ggactctatg acggtatttt ttctgtggag agaccagatg atttagtgga
    10981 tagaatgaag aatatagaga tagagtaatg agtgaattaa ttagtgttgt ggtaccgata
    11041 tacaatacgg gaaaatattt agtggagtgt gtcgagcata ttctgaagca aacctatcaa
    11101 aatatagaaa ttattttagt tgatgacggt tctacggata attctgggga aatttgtgat
    11161 gcttttatga tgcaagataa tcgtgtgcga gtattgcatc aagaaaataa ggggggggca
    11221 gcacaagcta aaaatatggg gattagtgta gctaagggag agtacatcac gattgttgat
    11281 tcagatgata tcgtaaaaga aaatatgatt gaaactcttt atcagcaagt ccaagaaaag
    11341 gatgcagatg ttgttatagg gaattactat aattatgacg aaagtgacgg gaatttttat
    11401 ttttatgtaa cagggcaaga tttttgcgtc gaagaattag ctatacaaga aattatgaac
    11461 cgtcaagcag gagattggaa attcaatagc tcggccttta tattgccgac atttaagttg
    11521 attaaaaaag aattattcaa tgaagttcac ttttcaaatg gtcgccgctt tgatgatgaa
    11581 gcaactatgc atcgctttta tcttttagcc tctaaaatcg tctttataaa cgataatctc
    11641 tatctgtata gaagacgttc aggaagcatc atgagaacgg aatttgatct ttcctgggca
    11701 agagatattg ttgaagtgtt ttctaagaaa atatcggatt gtgtcttggc tggtttggat
    11761 gtctccgttc tgcgtattcg atttgtcaat cttttaaaag attataagca aactttagaa
    11821 taccatcaat taacagatac tgaggaatat aaagatattt gtttcagatt aaagttgttt
    11881 tttgatgcag aacaaagaaa tggtaaaagt tgaaataaaa gaattgttat ttaccatatc
    11941 acaaacaatg aaggtgaggg gagtgtttta tgactaagat ttattcgtca atagcagtaa
    12001 aaaaaggact atttacctta tttctactgt ttatctatgt attgggaagt cgtattactc
    12061 tcccttttgt tgacctaaat actaaagatt ttttaggagg ttcaacagcc tatctagcct
    12121 tctcagccgc cctaacaggt ggaaatctaa gaagtttgtc aattttttct gttggattgt
    12181 ccccttggat gtcagctatg attttatggc agatgttttc tttttctaaa cggttgggtt
    12241 taacatctac gtctatagaa atacaagatc gccgtaaaat gtacctgacc ttgatgatag
    12301 ctgtcattca atcattggca gttagcttga gactgccagt acaatcctcc tattctgcaa
    12361 tattggttgt tctaatgaat acaatattgc tgatagcagg aacatttttt cttgtttggt
    12421 tgtcagattt aaatgcgagt atggggattg gaggttctat agtcattctc ctatccagta
    12481 tggttttaaa tattcctcag gatgttttgg aaacatttca gacagtacac attccaacag
    12541 ggattattgt gttacttgct ttattaaccc ttgtcttttc ttatttactt gcccttatgt
    12601 atcgagctcg ctatttggtt cctgttaata aaattggctt acacaatcga tttaaacgct
    12661 atttttatct cgaaatcatg ttgaatcctg caggtgggat gccttatatg tatgtgatga
    12721 gttttcttag tgtaccagct tatttgttca tcttgttggg atttattttc cctaatcatt
    12781 cagggttagc ggctttatca aaggaattta tgattggaaa gcctttgtgg gtctatgttt
    12841 atatttcggt cttattttta tttagtatca tttttgcttt tgttacgatg aatggagaag
    12901 agattgcaga ccgtatgaaa aaatctggag aatacattta tggtatttat ccaggtgcgg
    12961 atactagtcg atttattaat cgattggtcc ttcgtttctc agtcataggt ggtctcttta
    13021 atgtggttat ggcaggtggt cccatgcttt ttgttttgtt tgatgaaaag ttattacgat
    13081 tggcaatgat tccaggtttg tttatgatgt ttggaggcat gatttttacg attagagacg
    13141 aggtcaaggc tttaaggcta aatgagacct ataaaccttt gatttaggag acttttatgt
    13201 attattttat tccagcttgg tatgggtcag aaagaacatg gcatgcagat atcactccat
    13261 ggtatttttc tcattttcgt ctagagtttg atgatacctt tcaccagatc cggctctttc
    13321 aagagcaaga tatagattct cgtctattag tattagctta ccagcctcat ctacgttatt
    13381 ttttatatag acatggtgtg ttagaaacgg atacttattc cgtttttgat gttatgcaag
    13441 attttcataa tctccatacc caagttttaa gcattagaga tattgagtgg gatgatgact
    13501 gtgaatttat ttatagtccc tttacgatta tcgttcaaaa aaatgggaag aaatttgcta
    13561 aggttgaaca tggagttgaa ggcttcatca gtgatataca gtattttgaa ccaaatggtc
    13621 aaatacatat gcaccatatc atggatgatc gagggtttat atcgagtatt attttttttg
    13681 aagatgggca agcagcctat caagaatatt tgaatcctaa gggagtttgg caatttagag
    13741 agcgtttaaa agaaggagga caggtagaag tcaatccaat tttgggttat cgctttaaaa
    13801 tgcttaccta tcaaaatatg ggagatctgg tggcagaatt ttttgagaat tatctgcaaa
    13861 cgtatgtgaa ggatcaggat atttttatgc ttccttctca ttctcatcat gaccagttgg
    13921 tactagatcg tttacctagt actaatccta aactgttgag tctgttcatt ggacgtaatc
    13981 ctcaagatac ctttagggat ttagatgtaa cttttgaaaa atcggatttg attttggtgg
    14041 atagagagga tagtttacga ttgttgcagg agttgtatcc tgaacgaatg catcaatgtt
    14101 atcatttatc atcttttgac acccgattac gattgggacg aagccaaact aagaaagaat
    14161 ccatcattta ttttcaactg gattttgagc aggggattga taatcaagct ctgcttcaag
    14221 tcttgtcctt tgtcgctgaa aataaggata ctgaggtgat ttttggagcc tttgctgcta
    14281 gtcaggagca aatgaatgag gttgaaggga ttgttgagtc tttcatccaa gaaaacattc
    14341 aatccgaaaa tctgggaaag gcgattgatt atggtgatgc agaaaatccc ctggaagaaa
    14401 atcaacacca ggacttacgc ttacagtttg ttaacttgaa tgatgagtta gatttgataa
    14461 aaacactaga atttgtccgt ttgattgtgg atttaaatag acatcctcat ctctacacac
    14521 agattgctgg gattagtgca ggaattcctc aaatcaacct agttgaaacc gtctatgtgg
    14581 aacatttaaa aaatggttat ttgctgacag atgtgacaga attttctaag gctgcacatt
    14641 attacacaga taggttgaag gagtggaatg agtccttgat atattcaatt gataagatta
    14701 aggagcacac aggacaacaa tttcttggaa aattagagaa atggatagag gaggttaaaa
    14761 atgtcaaagg aacttaatat tttacagata ggacttgcca attgggaaaa tcactatgac
    14821 atacctgaaa atatgagttg gtattatttt tacccaaact catcaaaaac ccttcgtgaa
    14881 ataatcgaaa aagaggatat taaccgtttt catgcagttt taatagaaga tggtcagtat
    14941 tccagagact tattttccta tgtaaaatat tttgaacctt atactttgtt ctataaccag
    15001 aatctacaaa taaatgatag agaggttgtg gattttctaa aaaaacgatg tgcacaagca
    15061 attgattttt taagtcccca acaactaatc aatgatttaa gtaaatctct ttttggcggt
    15121 gggtatggtg ataaactctt tcctccgacg atacaagtca atccaaattt tacaggagct
    15181 atttcttatc aaggattgga ttatgtcagt ttggaaggtg agtttgggca agattttgcc
    15241 cagcttgcct attgggctta taatattatg gtgcaaaaaa cactccctat tgagttgtgg
    15301 cttgaatatg agaaggaagg caattgtgac tttcgtttag taatccgtaa aatgtggagt
    15361 gggtctgttg atgatttctt tgaagaagta atagtatctg aaaaagactt ggagcaagca
    15421 ctttttatgg atagtcgaga cggagactac tttctctcga tatctgttga agcaagaggt
    15481 cgtggaacta tcaaactagg taatcttcac caacgatgga gtcgaaaaca atttggtaag
    15541 tttgtacttg gtggaaatat cctacatgat tccaagcgtg atgaaataaa ctatttcttc
    15601 catccaggtg attttaaacc gcctttgact gtctattttg caggttatcg acctgcagaa
    15661 ggattcgagg gttactttat gatgaaaact cttggatgtc ccttcatttt attttctgat
    15721 ccacgtttag aggggggagc tttttatctc ggaacggatg agctagaggg aaaagtaaag
    15781 gatacgatca ctcactatct tgattattta ggctttgatc ataaggattt gattttatca
    15841 ggtctttcta tgggaacgtt tccggctctc tattatggtg cttcttttga accccatgcc
    15901 atcatagttg gtaagccctt ggctaattta ggaactatag ctagtcgtgg acgtttggac
    15961 gcaccgggtg tctctaactt agcttttgat tgtttaattc atcatacagg tgggacaagt
    16021 tctcaagata tgacggagtt ggatcagcgt ttttggaaaa tttttaaaca agcaaatttt
    16081 tcaaagacaa cctttggttt atcctatatg aaagatgaag aaatggatcc acaagcctat
    16141 gaacaattag tgtcttatct gtgtaataca ggtgcgaaga ttttatctaa aggaactgct
    16201 ggacgacaca atgatgatac agataccaat atttcttggt ttttgcactt ttatagaatg
    16261 gtcttagaga ctggttttgg aagggagaaa agatgattat tacacagaga cagtctattt
    16321 attggggaga agttggtggg acttatatgt atggaacaac tgtatcttat taccttgaca
    16381 aaagtgttcg tctgtataat cctctattgc catctggtga gattctaaag acttggtttt
    16441 ctagtgtcaa ttaccaggct gcacgaaccc aacctcagct tcccttatta aaaagaaagc
    16501 aggagtatca actatcactg gtttttgatt gtcagcctga aaatggagtt tataccaaga
    16561 taactttttt tgaccgctat ggtgatattt tagaaaaaaa ggtagaaaaa gcgaaagatt
    16621 tcatatttac ttatccagaa gatagttata cttatcaagt ttctctttta agtgctggat
    16681 ttgagtcctt aactttttat catttttcta tcaaggagat cagaagtgtt tagacgttta
    16741 ggtcaagatt tccagcttag gaaagtgaaa aagattttaa agcagattaa tgccctgaaa
    16801 ggcaagatgt cctctctttc ggatcaagaa ttagtagcta aaacagtaga gtttcgtcag
    16861 cgtctttccg agggagaaag tctagacgat attttggttg aagcttttgc tgtggtgcgt
    16921 gaagcagata agcggatttt agggatgttc ccctatgatg ttcaagtcat gggagctatt
    16981 gtcatgcact atggaaatgt tgctgagatg aatacggggg aaggtaagac cttgacagct
    17041 accatgcctg tctatttgaa cgctttttca ggagaaggag tgatggttgt gactcctaat
    17101 gagtatttat caaagcgtga tgccgaggaa atgggccaag tttatcgttt tctaggattg
    17161 accattggtg taccatttac ggaagatcca aagaaggaaa tgaaagctga agaaaagaag
    17221 cttatctatg cttcggatat catctacaca accaatagta gtttaggttt tgattatcta
    17281 aatgataacc tagcctcgaa tgaagaaggt aagtttttac gaccgtttaa ctatgttatt
    17341 attgatgaaa ttgatgatat cttgcttgat agtgcacaaa ctcctctgat tattgcgggt
    17401 tctcctcgtg ttcagtctaa ttactatgcg atcattgata cacttgtaac aaccttggtc
    17461 gaaggagagg attatatctt taaagaggag aaagaggagg tttggctcac tactaagggg
    17521 gccaagtctg ctgagaattt cctagggatt gataatttat acaaggaaga gcatgcgtct
    17581 tttgctcgtc atttggttta tgcgattcga gctcataagc tctttactaa agataaggac
    17641 tatatcattc gtggaaatga gatggtactg gttgataagg gaacagggcg tctaatggaa
    17701 atgactaaac ttcaaggagg tctccatcag gctattgaag ccaaggaaca tgtcaaatta
    17761 tctcctgaga cgcgggctat ggcctcgatc acctatcaga gtctttttaa gatgtttaat
    17821 aagatatctg gtatgacagg gacaggtaag gtcgcggaaa aagagtttat tgaaacttac
    17881 aatatgtctg tagtacgcat tccaaccaat cgtccgagac aacggattga ctatccagat
    17941 aatctatata tcactttacc tgaaaaagtg tatgcatcct tggagtacat caagcaatac
    18001 catgctaagg gaaatccttt actcgttttt gtaggctcag ttgaaatgtc tcaactctat
    18061 tcgtctctct tgtttcgtga agggattgcc cataatgtcc taaatgctaa taatgcggcg
    18121 cgtgaggctc agattatctc cgagtcaggt cagatggggg ctgtgacagt ggctacctct
    18181 atggcaggac gtggtacgga tatcaagctt ggtaaaggag tcgcagagct tgggggcttg
    18241 attgttattg ggactgagcg gatggaaagt cagcggatcg acctacaaat tcgtggccgt
    18301 tctggtcgtc agggagatcc tggtatgagt aaattttttg tatccttaga ggatgatgtt
    18361 atcaagaaat ttggtccatc ttgggtgcat aaaaagtaca aagactatca ggttcaagat
    18421 atgactcaac cggaagtatt gaaaggtcgt aaataccgga aactagtcga aaaggctcag
    18481 catgccagtg atagtgctgg acgttcagca cgtcgtcaga ctctggagta tgctgaaagt
    18541 atgaatatac aacgggatat agtctataaa gagagaaatc gtctaataga tggttctcgt
    18601 gacttagagg atgttgttgt ggatatcatt gagagatata cagaagaggt agcggctgat
    18661 cactatgcta gtcgtgaatt attgtttcac tttattgtga ccaatattag ttttcatgtt
    18721 aaagaggttc cagattatat agatgtaact gacaaaactg cagttcgtag ctttatgaag
    18781 caggtgattg ataaagaact ttctgaaaag aaagaattac ttaatcaaca tgacttatat
    18841 gaacagtttt tacgactttc actgcttaaa gccattgatg acaactgggt agagcaggta
    18901 gactatctac aacagctatc catggctatc ggtggtcaat ctgctagtca gaaaaatcca
    18961 atcgtagagt actatcaaga agcctacgcg ggctttgaag ctatgaaaga acaaatccgt
    19021 gcggatatgg tgcgtaatct cctgatgggg ctggttgagg tcactccaaa aggtgaaatc
    19081 gtgactcatt ttccataaga ggagaaaata tgacaattta caatataaat ttaggaattg
    19141 gttgggctag tagcggtgtt gaatacgctc aagcctatcg tgctggtgtt tttcggaaat
    19201 taaatctgtc ctctaagttt atctttacag atatgatttt agccgataat attcagcact
    19261 taacagccaa tattggtttt gatgataatc aggttatctg gctttataat catttcacag
    19321 atatcaaaat tgcacctact agcgtgacag tggatgatgt cttggcttac tttggtggtg
    19381 aagaaagtca cagagaaaaa aatggcaagg ttttacgtgt attctttttt gaccaagata
    19441 agtttgtaac ctgttatttg gttgatgaga acaaggactt ggttcaacat gccgagtatg
    19501 tttttaaggg aaacctgatt cggaaggatt acttttctta tacgcgttat tgtagcgagt
    19561 attttgctcc caaggacaat gttgcagtct tataccaacg aactttttac aatgaagacg
    19621 ggactccagt ctatgatatt ttgatgaatc aagggaagga agaagtttat catttcaagg
    19681 ataagatttt ctatggaaag caagcttttg tgcgtgcctt tatgaaatct ttgaatttga
    19741 acaagtctga tttggttatt ctggataggg agacaggtat tggacaggtt gtgtttgagg
    19801 aagcacagac agcacatcta gcggtagttg ttcatgcgga gcattatagt gaaaatgcta
    19861 caaatgagga ctatatcctt tggaataact attatgacta tcagtttacc aatgcagata
    19921 aggttgactt ctttatcgtg tctactgata gacaaaatga agttctacaa gagcaatttg
    19981 ccaaatatac tcagcatcag ccaaagattg ttaccattcc tgtaggcagt attgattcct
    20041 tgacagattc aagtcaaggg cgcaaaccat tttcattgat tacggcttca cgtcttgcca
    20101 aagaaaagca cattgattgg cttgtgaaag ctgtgattga agctcataag gagttaccgg
    20161 aactaacctt tgatatctat ggtagtggtg gagaagattc tctgcttaga gaaattattg
    20221 caaatcatca ggcagaggac tatatccaac tcaaggggca tgcggaactt tcgcagattt
    20281 atagccagta tgaggtctac ttaacggctt ctaccagcga aggatttggt ctgaccttga
    20341 tggaagctat tggttcaggt ctacctctaa ttggttttga tgtgccttat ggtaatcaga
    20401 cctttataga ggatgggcaa aatggttatt tgattccaag ttcatctgac catgtagaag
    20461 accaaatcaa gcaagcttat gccgctaaga tttgtcaatt gtatcaagaa aatcgtttgg
    20521 aagctatgcg tgcctattct tatcaaattg cagaaggctt cttgaccaaa gaaattttag
    20581 aaaagtggaa gaaaacagta gaggaggtgc tccatgattg aactttatga tagttacagt
    20641 caagaaagta gagatttaca tgaaagtcta gtcgctactg gtctttctca acttggagtg
    20701 gtcatcgatg cagatggttt tctgcctgat ggtctgcttt ctccttttac ctattatcta
    20761 ggttacgagg atggaaaacc tctctatttt aaccaagttc ccgtttcaga tttttgggaa
    20821 attttaggag ataatcagtc tgcttgtatt gaagatgtga cgcaggagag ggctgtcatt
    20881 cattatgttg atggaatgca ggctcgcttg gttaaacagg tagactggaa agacctagaa
    20941 ggtcgagtac gtcaggttga ccactacaat cgctttggtg cttgctttgc taaaaccact
    21001 tatagcgcag atagcgagcc gattatgaca gtttaccaag atgtcaatgg ccaacaagtt
    21061 ttactggaaa accatgtgac gggtgatatc ttattgactt tgcctggtca gtccatgcgt
    21121 tactttgcaa ataaagttga atttatcacc ttctttttgc aagatttgga aatagatacc
    21181 agtcagctta tctttaatac tctagcgact cctttcttgg tttccttcca tcatccagat
    21241 aaatctggct cggatgtctt ggtatggcag gaacctctct atgatgccat tccaggtaat
    21301 atgcagttga ttttggaaag tgataatgtg cgtactaaga agatcatcat tccaaataag
    21361 gcgacttatg agcgcgcttt agagttaact gacgagaaat accatgatca gtttgtgcac
    21421 ttgggttatc attaccagtt caaacgtgat aatttcctaa gacgagatgc cttaatcttg
    21481 accaattcag atcagattga gcaagtagaa gcaatcgtag aagccttgcc tgatgttacc
    21541 ttccgtatcg cagcagtgac agagatgtct tctaagctct tagacatgct tcgctatcct
    21601 aatgtggtcc tttaccagaa tgctagtcca cagaagattc aggagctgta tcaactgtcg
    21661 gatatttact tggatatcaa tcacagcaat gagttgttgc aggcagtgcg tcaggccttt
    21721 gagcacaatc tcttgattct tggatttaac caaacggttc acaatagact ttatatcgct
    21781 ccagaacatc tatttgaaag tagtgaagtt gctgccttgg ttgagaccat taaattggcc
    21841 ctttcagatg ttgatcaaat gcgtcaggca cttggcaaac aaggccaaca tgcaaattat
    21901 gttgacttgg tgcgatatca agaaataatg caaactgttt taggaggcta acatgtcaga
    21961 ggaagattta ttttacaaag acgttgaagg tcgcatggaa gagttgaaac aaaaacccat
    22021 caagaaggaa aaagaaaccc gaggggagaa gattagtaaa actttttcac ttttactggg
    22081 cttaatgatt ctgattggtt tgctctttac tttgttggga attttgaggt agatcaatga
    22141 ttgaaatgct aattgtttta gctattatcc tatctcttgc tttgattgta ttggtaacta
    22201 tacaaccccg tcaaaatcaa ctattttcca tggatgccac tagtaatatt ggtaaaccaa
    22261 gctactggca gagcaacacc ttggtcaagg tgctcacttt attggtgagt ttggctttat
    22321 ttgttctact attaaccttt atggtgatta cttataaata aaagaaaact tcagatattc
    22381 accttttgtg gattggtctg aagttttctt ttttatactc aatgaaaatc aaagagcaaa
    22441 ctaggaagct agccgcaggc tgctcaaaac actgttttaa ggttgtggat ggaactgacg
    22501 aagtcagctc aaaacaccgt tttgaagttg tagatagaac tgacgaagtc agctcaaaac
    22561 accgttttga ggttgtggat agaactgacg aagtcagctc aaaacaccgt tttgaggttg
    22621 tggatagaac tgacgaagtc agctcaaaac atcgttttga ggttgtggat agaactgacg
    22681 aagtcagtaa catatataca gcaaggcgac gctgacgtgg tttgaagagt attactgtct
    22741 atatttttgg taaaaatcaa cttttacttg gatgaaggtt ttggcttcac gtaggagttg
    22801 aagaagggtg gcgcgggttt caaattcttc tcttgtcttg ggcagactgc ggttccggaa
    22861 gacttccaga taacgttcaa tttcatctag caaatcagaa gcaggattgg tctggctcag
    22921 ttgacctgca atttttgaaa agagttgcgc taagatcagg ctttcactgg cggcaaggtg
    22981 acaagtgtta atctgttggg ccatgtttct caggatacga ctttgtcgtt gtctcatctc
    23041 aaagtagtgg atatggtagt cggtctggtg aaagaggtgg tcagagtgat ccaaatagac
    23101 cagtctgagg gcttctttca aaagcgtgtc taattctgct accagctgtg ctcggttgcg
    23161 tccgtctcct ctggataaat agtatttgaa gcgctggagg atatctttta acttttcttc
    23221 caccagcgtg tggtagtgct ggatttcctc ttctcgtgaa ggcatataga gattaacaag
    23281 caaggcaaat cctgtaccga tagcaaagag aaggaattcg ttgactagga ggtctggaga
    23341 ggttgactct tgaaccaaga gatggctaac caaaaccgtg cttggtgtga tgccaatttc
    23401 ccagcccatc ttgtaggcta aaggaacgta gaaggccaga tagaggccga gactccagat
    23461 atgaaatccg ctcaagtgaa aagctagaac accgatagcc agagctagaa gcatagaaaa
    23521 aagacgattg cgagccagtt ttaaagtact tctacgcgta tcagataggc tcaagagagc
    23581 gataattcca gccgaaactg ctgacgaaag attgagaaaa taagcaaaca ggcaggcaag
    23641 acaggtagct aagatgagct tggtcgtacg ttggctaata gacataagaa tttcctaata
    23701 agttagaata aaagcgtaaa agacaagaca tgagcaggct tgccttgatg agttattttt
    23761 tacgggttgc tgcgtattcg gcaacggcgg taaagaggac atctgtagaa gagttaaggg
    23821 ctgtttcaca tgagtcttgg atgacaccaa tcacaaaacc aaccccaaca atttgtatgg
    23881 caatatcgtt agaaataccg aaaaggctac aagcaactgg gataagaagg agggaacctc
    23941 cggcaatacc tgaagcacca caggctgaga tagctgctac cacactgagg acaaaggctg
    24001 tggcaaagtc aacaggaatt ccaagagtgt taactgtaac aagggtcaaa aggttaatgg
    24061 taatcgctac tccagccata ttgatagtag aaccgagtgg gatagaaaca gaataggtat
    24121 ctgggttgag tccaaggtca tggcagagtt tcatattgac aggaatgtta gccgcagaac
    24181 tacgagtgaa aaaggctgtc acaccgctga cacggaggca gttccaaact agagggtaag
    24241 gattgcgtct cataaagaag aaggcaatca aagggttgac cacaggggca acaaaaagca
    24301 tagtcgttac taatagaacc aataaaatac cgtagttggc aagccttccg actcccttgt
    24361 cagaaatggt tttaaaaaca agaccaagga ttccaaatgg agtcagattg atgatccatt
    24421 cgacaatttt agaagtcacg tcagcgatag tttttagcaa ttctttacta tttttactgg
    24481 cttctctcat agcgattcca aaaatgactg cccaagataa gattccaata tagttagcag
    24541 taagcagggc gttgactggg ctgtcaacca gtttgagcaa gaggttgctg aggacctgcc
    24601 caatcccatc tggtggtgca atttcagtat tggcactatt tagggtaatt tcaataggga
    24661 cgatgaaact tgctagtaca gctacaagag cagcggcgaa agtccctatc ataggatata
    24721 caagaaaaca acagttttca tattgctatc ttgtcccttt tgatgttggg aaagggcatt
    24781 ggcaacgaga gcaaagacta ggataggagc aacagctttt agacctccaa cgaataaatc
    24841 cccgagtagc ccaatccctg agagattagg aagggtcagt cctaggattc cccacaaagc
    24901 ataccaatca agatacgctt gacaaggctt gccttattcc aagcatgaat gattcttttc
    24961 ataataatct cctttttgtg tagtgattat gattatagta taaatgatag acaaaatcaa
    25021 gaattttctg tctatttttt gaatatttat ggagaatgag actgatgaaa atatggtata
    25081 atgaaataaa ggagttttat atgcaaaaat ttattcaggc ttatattgaa aagctagatg
    25141 tgacaaccat tatcgagaat attctaacca aggtcatttc tcttttactg cttttgattg
    25201 tattttatat tgctaaaaaa atgcttcata ccatggtgca gagaattgtc aaaccttctc
    25261 taaaaatgtc tcgtcatgat gtcggacgcc aaaaaaccat ctcacgttta ctagaaaatg
    25321 tgtttaatta tacgctatat ttctttttac tctactgcat tttgtcgatt ttaggtttgc
    25381 cagtttctag tttgctggct ggagctggta ttgctggggt agcgattggt atgggagccc
    25441 aaggctttct gtctgatgtc atcaatggct ttttcatcct ctttgaacgt caactggatg
    25501 tgggagatga ggtcgttctg acaaatggac cgattactgt atcgggtaag gttgtcagtg
    25561 tgggaattcg tacgacacag cttcgtagcg aggagcaagc ccttcacttt gtccctaacc
    25621 gaaatatcac agttgttagc aatttctcac gcacagacta gacctgttat tttaagtaat
    25681 ttgtggtaca atagagggag tttaataagg agaaaagatg gttttagaaa agcagttggg
    25741 ccatggttgt acctggatag acctagacct aggaaagttg aataaactag aagacctttc
    25801 tgaaatttac ggtttggaca aggaaaccat tgaatacgca ctggatagaa acgagcgcgc
    25861 ccacatggac taccaccgtg aaagtgggac ggttaccttt atctataatg tcctagacgt
    25921 aaaaaaggac aaggcctact atgagacttt tcccatgacc tttatcgtcg agcatcgtcg
    25981 cctgattacc attagtaata ccaagaacgc ctatgtcatt gaacagatga ctcgttatct
    26041 ggagagccat gacacgcttt cgatttataa gtttctcttt gccagtctgg aaatcatcag
    26101 caatgcctac tatcctgtca ttgagcagat ggacaagagt agggatgagg tcaatgacct
    26161 cttgcgccag cgaactacca agaaaaacct ctttgccctg tctgatttgg agactggtat
    26221 ggtttatctg acggcagctg ccaaacaaaa tcggattttg ttagagcata ttcaaggtca
    26281 tgccttgtat cgtagttttg atgagattga gagagaacag tttgatgatg ccatgattga
    26341 ggctcatcag ctggtatcca tgacagacct aatctctcag attttacagc agctttcagc
    26401 ctcttacaac aatattctaa acaataatct gaatgacaat ttgacaacct tgactatcat
    26461 ttcagtcttg ctagctgttt tggcagtcgt gacaggcttt ttcggaatga atgttccctt
    26521 acctttaaca gatgagcccc atgcttggct ctatatcagt ttggctagtg caggtttgtg
    26581 gattgtttta tccttgttac taaggaaaat tgcgaaaaaa agttaagaaa aggagccaga
    26641 atggcgattg aaaattatat accagatttt gctgtggaag cagtctatga tctgacagtc
    26701 ccaagcctgc aggcgcaggg aatcaaggct gttttggtcg atttggataa taccctcatt
    26761 gcttggaaca accctgatgg aacgccagag atgaagcaat ggctacatga ccttcgggac
    26821 gcgggtattg gcattatcgt agtgtcaaat aacaccaaaa aacgcgttca acgagcagtt
    26881 gagaaatttg ggattgatta cgtttactgg gccttgaagc ccttcacatt tggtattgac
    26941 cgtgccatga aggaattcca ctatgacaaa aaggaagtgg tcatggttgg cgaccagctc
    27001 atgacagata tacgagcagc ccaccgtgca gggattcggt caattttagt caaacccttg
    27061 gtccaacatg actcaatcaa aacgcagatt aaccgaactc gtgagcgtcg tgttatgaga
    27121 aaaatcactg aaaagtacgg accgattaca tataaaaaag gaatttaact atggaagaaa
    27181 ttctctgtat tggttgtgga gcaaccattc agacgacaga taaagctggt cttggtttta
    27241 ccccccagtc ggcacttgaa aaaggtttgg agactggcga agtctattgc caacgctgtt
    27301 tccgtctccg ccactacaat gaaatcacag atgtccagtt gacgaacgat gatttcctca
    27361 agctcttgca cgaggtggga gacagtgatg ccttagtggt caatgtcatt gatatctttg
    27421 attttaatgg atctgtcatc ccaggtttac cacgtttcgt ctcgggcaat gatgtcctct
    27481 tggtaggaaa taaaaaagat atccttccta agtcagttaa gtctggtaag attagccagt
    27541 ggctcatgaa acgtgcccat gaagaaggtc ttcgtccagt cgatgtggtc ctaacttcag
    27601 cacaaaataa acatgccatt aaggaagtca ttgataagat tgaacactac cgtaagggcc
    27661 gcgatgtcta tgtggtcggt gtgaccaacg ttggaaaatc aactctaatc aatgctatta
    27721 tccaagaaat cacgggtgat cagaatgtca tcactacttc acgcttccca gggacaacct
    27781 tggacaaaat agagattccg cttgacgacg gatcttatat ttacgatacg ccgggaatta
    27841 tccaccgcca ccagatggct cactacttga cggccaaaaa cctcaagtat gtcagtccta
    27901 aaaaggaaat caagcctaag acctatcagc ttaatcctga gcaaacccta tttttaggtg
    27961 gtttgggacg ctttgacttt atagcaggag aaaagcaagg atttactgct ttctttgata
    28021 atgaactcaa actccatcgt agcaagcttg aaggagctag tgctttctac gataagcacc
    28081 tgggaactct tctgacacca ccaaatagca aggaaaaaga agatttccca aggctagtcc
    28141 agcatgtctt taccattaaa gataagacag acctagtcat ttcaggccta ggctggattc
    28201 gtgtaacagg cacagcaaaa gtcgccgtct gggcaccaga aggcgtcgcc gtcgccacac
    28261 gaaaagcaat tatttaaaac aaaatcgctg agcgaacaaa gtgagctcat atagcgatag
    28321 ttattgccgt ggtgtgattg ccaatctgta gattggcaag gggcacaatt gagaccaagg
    28381 ctcaattgtg aggtcaggaa atccattttt caaagatgaa atctttggaa aattagttcc
    28441 gaccgtccct caccacctaa aataactatc aaaaaacaag gaagaaaatt atgtcattag
    28501 catcaaaaca acgtgccttc ctcaacagcc aggcacacac cctcaaacct atcatccaaa
    28561 tcgggaaaaa tggactcaac gaccaaatca aaaccagcgt ccgtcaagct cttgatgcgc
    28621 gtgaattaat caaggttact ctcttacaaa acacagatga aaacatccac gaagtagctg
    28681 aaattttgga agaagaaatc ggtgtggata cagtccaaaa aataggacgc atcttgattt
    28741 tgtttaagca atctagcaag aaagaaaatc gcaagatttc taagaaagtc aaagaaatct
    28801 aagaccgaaa ctccaaataa ctgtttttat agagaaataa aggggactag cctatgacaa
    28861 tcgaactatt gactcccttt accaaggtag agttggagcc agaaatcaag gagaaaaaac
    28921 gcaaacaagt tgggatttta ggggggaatt ttaaccctgt tcacaatgcc catctcattg
    28981 ttgcggatca agtacggcaa cagttgggac tggatcaagt tcttctcatg cctgaatacc
    29041 aacctcctca cgttgataaa aaggaaacca tccctgaaca ccatcgtctc aagatgcttg
    29101 agttggcaat tgagggaatt gacggcctag tcattgaaac cattgagttg gagcgcaagg
    29161 gtatttccta cacctacgac accatgaaga ttttgacaga gaagaatcca gatacggatt
    29221 attactttat catcggtgcc gacatggttg actatctgcc taagtggtac cgaattgatg
    29281 aactggttga catggttcag tttgtggggg ttcagcgtcc acgctacaag gtagggactt
    29341 cctatccagt tatctgggtg gacgtaccgc tcatggatat ctcgtccagc atggtgcggg
    29401 acttccttgc ccaaggtcgg aaacccaact ttctcctacc tcagccagtg ctagactaca
    29461 tcgagaagga ggggctctac tgatgtccta tcaagactat atcaactgct cccgtgaggc
    29521 cttgttggaa aaaatggcag agtttctacc tgagaaacgt ctaacccatt gtctaggtgt
    29581 ggagcgtgcc gctatggaat tagctcagcg ctttggtgta gatgttgaga aagcaagtct
    29641 agcaggtctt cttcatgact atgctaaaaa gttgtcaaat caggaatttc tagccttgat
    29701 tgaccgttac cagctagacc ctgacctcaa aaactggggc aataatgtct ggcatggtat
    29761 ggtcggaatt tacaaaattc aggaagattt ggatttgcat gattcagaaa tcctgcgagc
    29821 cattgaagtc catacagtcg gtgctggtca aatgacagac ctagataagg tcatctacgt
    29881 cgcagactat atcgagcaca atcgagcctt tcctggagta gatgtggcgc gtgagattgc
    29941 aaatctatcg ctcaataagg cggtggccta cgaaacagct cgtaccgtgg agtatctagc
    30001 tcatcaggga ttccccatct atccccaaac ccttgaaacc tataacgcct ttgtgcacta
    30061 tttgaaagag aactaaatga agacggcttt tataatcatt gatgttcaga atattttagt
    30121 agaaactggg ttccagacaa aaagtctatt gggaaaaatt tcttatttac aaaaccaggc
    30181 tagaagcaag aatattgaaa ttatctatgt tcaacatatt gagaactctg aagctcaaac
    30241 atcagaagat tggcagttat ctgcgctttt aaatcgaaaa cctgctgaaa aggtctttca
    30301 gaagaagtat aacagtattt tcaaagaaac tggcttaaaa gaatacttgg ataagcaggg
    30361 gattgaaaaa ttagttttat gtggtatgca gacagaatat tgtgtggata cctctgtcaa
    30421 ggttgccttt gaatatggct atcagcttat tgttccagaa ggtgctgtca caacctttga
    30481 tggggatgac attccagcag aaacgattaa tgaattttat gaggacattt gggaggagcg
    30541 ctttgcagat gttctagatt acaaacatat tttctaaaaa gaggattaaa tgaacgaaaa
    30601 agaattacta gaactagtcg tgaaagcggc tgatgagaaa cgtgcggagg atatcctcgc
    30661 acttgatgta caagatttga ctagtgtgac ggactacttt gtcatcacta gctcaatgaa
    30721 tagccgtcag ttggacgcta tcgcagctaa tatccgtgaa aaagtagctc aagcaggctt
    30781 taaaggtagc catgtcgaag gcgatgcagc tggaggctgg gtcttactgg accttggtgc
    30841 tgttgtcgtg catatctttt cagaagaaat gcgtgcccat tataatctag agaagctatg
    30901 gcatgaggcg aattcagtag atatttcaga agctcttgct tagaagatga actcagttgt
    30961 agtcaactgg gtttctttgc ttattttaga aaaattgata gaaaggtaaa gggcctcgtg
    31021 tttgtttcat ttcgaaactg aacacgagct aaaagctgag ataaaaagta actttctttg
    31081 tatctgacga tagggaagaa agtttcctat gtactctttg cttttaaggc tctttgtatc
    31141 ttagaaagga tttgaacccg tcctgtaatt ctcggaaaat agatagcctt ccttggagct
    31201 cggctccatc gtaaggctcc taattttcta tcgaattacg ggcggacttg gtatcatgtt
    31261 ttatggcgac ttatgaaacc tttgcggcgg tctatgatgc ggtcatggac gatagtttat
    31321 acgacaaatg gacgaatttt tctctgcgtc atttgcctaa gaccaaggag agaaagaaac
    31381 tcttggaatt ggcttgtggg acaggaattc aatcagtgcg cttttctcag gctggttttg
    31441 atgtgactgg acttgacttg agtgcggata tgttgaagat tgcggagaag agagcaactt
    31501 cagccaagca aaagattgct tttatagaag gtaatatgct gaatttgtcc aaggcaggga
    31561 aatacgattt tgtcacgtgt tattcggact ctatctgcta tatgcaggat gaggtggaag
    31621 taggggacgt ctttaaggac gtgtacaatg cgctgaatga agagggagtt ttcatctttg
    31681 acgtgcactc gacctaccag acagatgaag tattccctgg ctattcctac catgaaaatg
    31741 cggaagattt tgccatgctt tgggatacat atgaggacga agttcctcac tccatcgtgc
    31801 atgagctgac tttctttatc aaggaggctg acggttcctt tagtcgccac gatgaagtac
    31861 atgaggagag gacctatgag atcttgacct atgatatctt gctggaacag gctggattta
    31921 agtccttcaa actctatgca gactttgagg ataaggagcc aacagaaact agcacccgtt
    31981 ggttttttgt ggcgcagaag taggagatta gcatgaccat aacaggtatt atcgcggagt
    32041 tcaatccttt tcataatggc cataaatacc tgctggatca ggcagaggga ctgaaaattg
    32101 ttgccatgtc agggaatttc atgcagcgtg gagagcctgc tattgtggat aagtggacaa
    32161 gggcccagat ggcgctggaa aatggcgcag acttggtagt ggaattgccc tttttagtca
    32221 gtgttcaggc agctgatttc tttggtcaag gagctgtgga tatcttggat cgcttgggca
    32281 ttgatagtct agtttttggg acagaggaag ttctggatta ccagaaaatc gctgacttat
    32341 acacagagaa aggtgctgag atggagaaat ttgtgaaaaa tctgcctgat tccctttcct
    32401 atccccagaa aacccaagct atgtggaagg aatttgctgg tcttgatttt tcaggtaata
    32461 cccccaatca tgttcttgct ctggcctatg ccaaggcggt tgcaggacga aatatcaagc
    32521 tgcatccgat tcagcgtcag ggggcaggtt accattctgt gaataaagat gtggactttg
    32581 cctcggcgac agccctccgt caacatcaga aggaccaaga tttcttagaa cgttttatgc
    32641 cttctgttgc cctatttgag caggccagta aggtgatctg ggaagactat tttcccttgc
    32701 tccgctatca aatcttgtca aatcccgacc taaccaccat ctatcaggtc aatcaagaaa
    32761 tggctgtgcg cattaaagaa gctattaaaa cagcccagtc tgtggaagaa ttggtcgagt
    32821 tagtgactac caaacgttac accaaggcgc gtgtcagacg cctattgacc tatattttgg
    32881 tacaggctag agaaaatgtc ttgccagaag ccattcatgt ccttggattt actgaaaaag
    32941 tcaggcaaca tctcaagtct ctgaaaggac aggtcaatct agtcagccga attggcaaag
    33001 aaccttggga tgctatgacc caaaaagcag accagattta ccaactaggg aagccaagta
    33061 tagcagagca aaattttgga agagtgccga ttagaataga aacaaactaa gtctaccgaa
    33121 aggtaggctt tttgagattt tttacgaata atactcttcg aaaatcaaat tcaaatcgcg
    33181 tcaacgtcgc cttgccgtac tcaagtacag cctgcggcta gtttcctagt ttgctctttg
    33241 attttcattg agtataaata gatagaaaag aaaatcttgt acaagttcct gacaatttct
    33301 ttcttttcgt gtataatagt ggaaaagagc taaaacgagg tatggttatg gaagcagtcc
    33361 tttactcaac attccgaaat catttaaagg actacatgaa gaaggtaaat gatgaatttg
    33421 agcctttgac ggtggtcaat aaaaatccag atgaggacat tgtagttctt tcaaagagcg
    33481 aatgggacag tattcaggaa accctgagaa tcgcccaaaa taaggagtta tcagacaagg
    33541 ttttgcgagg aatggctcaa gtccgtgctg gaagcactca ggtccatgtg attgaggagt
    33601 gatgaatgct actcaagttt acagaagatg cctgggcaga ttattgctac tgacaaaacc
    33661 aagataaaaa aacactaaaa agaatcaata aattaatcaa ggatattcaa cgcgatccat
    33721 ttacaggaat aggaaaacca gagccactca aatatgatta ccaaggagcc tggtcacggc
    33781 gtattgatgc agaaaatcgc ttgatttata tgatggatgg agatagcgtg gctttcttgt
    33841 cctttaaaga tcattactaa gtctactgca aagtaggctt tttctcaagt ctctactaaa
    33901 ctactatttc taaacaacaa gtttattttg gtaaatgtgt tccaaattcc ccaaaacata
    33961 ttctatttta ggtttgtgaa aatcactttt ttatggtaga atgtaaaaga atgtatgtca
    34021 ttcggaataa caataaaatg aggtaaaaac atggaaatca tgtcgcttgc gattgctgtt
    34081 tttgccgtca tcattggttt agtcattgga tatgtcagca tctcagctaa gatgaaatca
    34141 tctcaggaag ctgcagagtt gatgctttta aatgctgaac aagaagcaac taatttacgt
    34201 ggacaagctg agcgtgaagc ggatttactt gttaatgaag ccaaacgtga aagcaagtct
    34261 cttaaaaaag aagcactatt ggaggccaaa gaagaagcca gaaaataccg tgaagaagtg
    34321 gacgctgaat tcaaatcaga acgtcaagaa ctcaaacaaa tcgaaagtcg tttgacagag
    34381 agagctacta gccttgaccg taaggacgac aatttgacga gtaaagaaca aacacttgaa
    34441 caaaaagaac aaagtatttc tgatagagcg aaaaaccttg atgcgcgtga agagcaatta
    34501 gaggaagtcg aaagacaaaa agaagcagaa ctagagcgta ttggtgctct gtctcaggca
    34561 gaagcacgag atattatctt ggctcagaca gaggaaaact tgaccaggga gattgccagt
    34621 cgcattcgcg aagctgagca agaggtcaag gaacgttctg acaaaatggc caaggacatc
    34681 ttggttcaag ctatgcaacg tatcgctggt gaatatgtag cggagtcaac aaactcaaca
    34741 gttcatctgc cagacgatac tatgaaggga cgcattattg gtcgtgaagg tcgtaacatt
    34801 cgtacctttg aaagtttgac aggggtcgat gtgattatcg acgatacacc agaagtggtg
    34861 accttgtcag gatttgatcc gattcgtcgt gagattgccc gtatgactat ggaaatgttg
    34921 ctcaaagatg gtcgtataca tccagctcgt atcgaagagt tggttgagaa aaaccgtcaa
    34981 gagattgaca ataagattcg tgaatacggt gaggctgctg cctatgaaat tggtgcgcca
    35041 aaccttcatc cagacttgat gaagattatg ggacgtttgc agttccgtac ttcatatgga
    35101 caaaatgttt tgcgccattc gattgaggtt gctaagttgg ctggtatcat ggcgagcgaa
    35161 cttggtgaaa atgcggctct tgcccgtcgt gctggattcc ttcacgatat cgggaaagcc
    35221 attgaccatg aggttgaagg tagccacgtt gaaatcggta tggaattggc ccgtaagtac
    35281 aaggaacccc cagttgtggt gaatacgatt gctagtcacc acggagatgt tgaagctgag
    35341 agcgtgatag cagttatcgt cgctgcagca gatgccttga gcgcagcccg tccaggtgct
    35401 cgtagtgagt ctcttgaaag ctacatcaag cgtctccatg atttggaaga aattgctaac
    35461 ggctttgaag gagtgcaaac tagctttgcc cttcaagcag gacgtgaaat tcgtatcatg
    35521 gtcaatccag gaaaaatcaa ggacgacaaa gtcacaatct tggctcacaa agttcgtaag
    35581 aaaattgaaa acaatctcga ttatccagga aatatcaagg taaccgtgat tcgcgagctt
    35641 cgtgcagtag attatgctaa ataaataaga aagagcagtt gaaaaattac tgcttttttg
    35701 ttacactaga tagaaagact gtaaaggata atctggcttt ttgccattat tctagagaaa
    35761 tgttatttca cagattgact aaaaggagac acaatggcag accgaggctt actaatcgtt
    35821 ttttctggtc cttcaggggt tggaaaagga acggttagaa gagagatttt tgagagttct
    35881 gaaaaccaat ttcaatattc tgtatcgatg acgacacgcg cacaacgtcc tggagaagtg
    35941 gacggtgttg actatttctt ccgtactcgt gaagaatttg aagagctgat tcgtcaagga
    36001 cagatgttgg aatacgcaga atatgtcggc aactactatg gaactcctct gacctatgtc
    36061 aatgaaacct tggacaaggg aatcgatgtt ttccttgaaa ttgaagttca gggtgctctt
    36121 caggtcaaga aaaaggttcc agatgctgtc tttatcttcc tgacaccacc agatttggat
    36181 gaattgcaag atcgcttggt aggtcgtgga acagatagtg cagaagtgat tgcccaacga
    36241 atcgaaaagg ccaaggaaga aattgccctc atgcgtgagt atgattatgc gattgtcaac
    36301 gatcaggtgc ccctagctgc tgaacgtgtc aaatgtgtga ttgaagcaga acacttctgt
    36361 gtggatcgtg tcattggtca ctatcaggag atgttaccaa aatctccaac tacccgataa
    36421 aatttagaaa ataggtacaa gcaaatgatg ttaaaaccct ctattgatac cttgctcgac
    36481 aaggttcctt caaaatattc actcgtaatc ttggaagcaa aacgtgccca cgaattggaa
    36541 gcaggtgccc cagcaactca aggtttcaag tctgaaaaat caactcttcg cgctttagaa
    36601 gaaatcgaat caggaaacgt tacaattcac ccagatccag aaggaaaacg tgaagcagtg
    36661 cgtcgccgta tcgaagaaga aaaacgccgc aaagaagaag aagaaaagaa aatcaaagag
    36721 caaattgcta aagaaaaaga agatggtgaa aaaatttaag gttgggggga ctcaatctta
    36781 ttttttctat tgcaagaatg tactgacaag gaggaggtga gaagatggcc ctagctaaga
    36841 ttatcgtaga tgtgcccttg atgcagacgg accagcccta tagttacagg attccggagg
    36901 aatttgaggg aatgctggaa gttgggatgc gggttcatgt gccttttggt aagggtaatc
    36961 gcctgattca agggattgtt cttggtttga agtcccaatc agatggagaa gagatggagc
    37021 aagatttaaa agatattgca gaggtgctgg atttttctcc tgttctcacg ccagaacaac
    37081 tctggctggc tgaggagtta cgcaaatctg tcttctccta caaaatctct atcctcaagg
    37141 ccatgcttcc agggtttctg aattctagct atgacaagat tctctatcct ctggaaggct
    37201 tgagtcagga agaacgagta cgcctgtttg gttcagaaga ttcgctagcc ttttcttcac
    37261 tagaccttgc caagcaagct gaaatgatgc gtttgactag aaaaggcctg cttggtctgg
    37321 aatatcaggc agtcgatcaa aagaaggtca agacccagtc ttggtatgag gttgaccatg
    37381 cccaattaga aggtgttgag atttctacac gtgccaagaa aaagttggaa ctgagagatt
    37441 atctgctgtc tcatccagag agcgcttcct tggctagctt gttagagtcc tactcgcgag
    37501 agcaagtcaa cttctttgtg gatcaaggta ctgttaccat agtccaaaag gaagttcaac
    37561 gctcggctgc ttattttgaa ggaattgaag caagtagacc tttggagtta aatccagaac
    37621 aaagacaggc gcgtgatgcg gttgtgagtt ctattggcag ttctcaacct ccctttctac
    37681 ttcaagggat tacaggaagt gggaagaccg aggtttactt gcagattatc caaggtgccc
    37741 tggataaggg taagacagct attttgctgg tacctgagat ttccttgact cctcagatga
    37801 ccgagcgttt tatagcacgt tttggggaca aggtagccat tcttcactca ggattatcca
    37861 atggcgaaaa gtatgatgaa tggcgcaagg tggagcgtgg cgatgcccaa gttgttgttg
    37921 gtgccagatc tgctatcttt gctcctctga aaaatctggg tgtcatgatt attgatgaag
    37981 agcatgaagc ggcttataag caggacagca atccccgtta ccatgccaga gaggtagcta
    38041 ttttacgggc tcagtataat caagcaactc tggtacttgg atctgcaacg ccgagcttag
    38101 agagccgggc acgtgctggc aaaggcgtct atcaacactt acgtctaacc caacgtgcca
    38161 atcctttggc tacaatccct gaggttcaag tgattgactt tcgagactat atcggacaaa
    38221 atgagacgtc aaactttacg cctcctttgc tagaggctat ccaagaccgt ctggttaaaa
    38281 aagagcaggt ggttctcatg ctcaatcgcc gtggttattc tagctttgtc atgtgtcggg
    38341 agtgtgggac ggtggatact tgtcccaact gcgatatttc tctgaccttg catatggata
    38401 ccaagactat gaactgccat tattgtggtt tctcgaagga tattcctcag gtctgtccta
    38461 actgtaagag ccgcagtatt cgttactatg ggacgggaac tcagaaggct tatgatgagc
    38521 tagcagaact ctttccccaa gctcgcattt tgaggatgga tgtggatacg actcgaaaga
    38581 aaggcagtca ccaagccttg cttgaccagt ttgggcgagg ggaagcggat attttacttg
    38641 gtactcagat gattgcaaag ggtttggatt ttcccaatgt taccctagtc ggagttctaa
    38701 atgcggatac ggccttgaat ctgcctgatt tccgttcttc tgagagaacc ttccagctct
    38761 tgactcaggt ggcaggtcga gcaggtcggg ctgaaaaagc aggtcaagtc ttgatacagt
    38821 cctacaattc gcagcactat gctattcgat ttgccaagga tcaagattac gaaggctttt
    38881 atgcctatga aatgggaatc agacgacaac tcggctatcc accttactat ttcacgattg
    38941 gtattaccct ttctcacaag aaagaagaag aggttttcaa acgtgcctat gaagtcatga
    39001 acattttgcg gtcaggcttg tcagagacca gtcccattct ggggccaacg ccaaaaccga
    39061 ttgcccgtac ccacaacctc tatcattacc agattttaat taaataccgt ttagaagatg
    39121 agctggggcc gaccctcaac caggtcttgg ccttgactca agaacgggaa aatagtgagc
    39181 tccgtctcag cattgaccat gagccgcagc aatttttata agaaggagaa gatatgacaa
    39241 aactaatctt tatggggacc cccgactttt cagcaacagt cttaaaagga cttttgacag
    39301 atgaccgtta cgaaattcta gccgttgtga cccagccaga ccgtgctgtt ggtcgtaaaa
    39361 aagttatcca agaaacccca gtcaagcagg ctgccaagga agcaggacta tctatctacc
    39421 aacctgaaaa attatctgga agtccagaga tggaagaact tatgaagcta ggagcagatg
    39481 gaattgtgac tgctgctttt gggcagtttc tcccaagcaa actccttgat agcatggact
    39541 ttgctgtcaa cgttcatgcc tccctccttc ctagacaccg tggtggtgcg cctatccatt
    39601 atgccttgat tcaaggggat gaggaagctg gtgtgaccat catggaaatg gttaaggaaa
    39661 tggatgcagg agatatgatt tctcgtcgca gcattccgat cacagatgag gacaatgttg
    39721 gcaccttgtt tgaaaaattg gcgctagttg gtcgtgattt gcttttggac actctgcctg
    39781 cctatattgc tggtgatatc aaacctgaac cgcaggatac gagtcaggtt accttctctc
    39841 caaatataaa gccagaggaa gaaaaactgg actggaacaa aaccaatcgt caactcttta
    39901 accaaattcg tggaatgaac ccctggcctg ttgcccatac tttccttaag ggcgaccgct
    39961 ttaagattta tgaagcccta ccagtagaag gtcagggaaa tccaggtgag attctctcta
    40021 tcggcaagaa agaattgatt gtcgcaacgg ctgaaggggc tctatccctc aaacaagtgc
    40081 agccagctgg taagcctaag atggacattg cttccttcct caatggagtt ggacgtacat
    40141 tgactgtagg agaacgattt ggtgactaaa gtagaaacgg ctagaagttt agctctagca
    40201 gtgctagagg atgtttttgt gaatcaagca tattcaaata ttgccttaaa taaacacctc
    40261 aaggggagtc agctctctgc agcagacaag ggcttagtga ccgagctagt ctatggaacg
    40321 gtagcccgta aactgactct ggaatggtac ctatcccact ttatcgaaga cagagaccag
    40381 ttagacagct ggctctatgt ccttcttctc atgagtgcct accaactccg ctatttggac
    40441 aagattccag atcatgctgt ggtcaatgaa gcagtggaat tggccaaact ccgtaaaaaa
    40501 ggcagtgaaa aattggtcaa cgctgtcctt cgccgtatct tgcgtgaagg ctggccagat
    40561 attgctagca tcaagcgaaa aaacaagcgt gactccattg cctattctct cccagtttgg
    40621 ctagttgcca aactcaagga agaatacgga gaggagagag caaaagccat ctttgaaagc
    40681 ctgttagtgc gaaacaaagc cagtattcgt gtaacagacc taagtcgaaa agaggaaatc
    40741 caagccttgt tggaggcgaa taattccctt ttagcaacca ctggtctggt taaggagcag
    40801 gggcattttg cagggcataa tttgtttgcg gatggagcca ttaccatcca agacgagtcc
    40861 agtcagttgg ttgctccgac gcttgattta caaggtgatg agcgagtgct tgatgcctgt
    40921 gcggctccag gtgggaaaac agcccatata gcctcttatc ttacgacagg tcaggttact
    40981 gctctggact tgtacgacca caagttggat ttaattcaag aaaatgccca acgtctggga
    41041 gttgaagatc gggttcaaac tcaaaaattg gatgccagaa aggtgcatga gttttttgac
    41101 caggattcct ttgataagat tttggtggat gctccttgtt caggaatcgg tcttttgcgc
    41161 cgaaaaccag atatcaaata caataaagaa acggcagatt tcgcgtcctt gcaggaaatt
    41221 cagttagaaa tattaggtag tgtttgtcaa atactaggca aaggtggtat aataacttat
    41281 agcacctgca ctatcgtctc agaggagaat tttcaagtcg ttaaggcctt tttagagagt
    41341 catcccgagt tcgagcaggt aaaactagaa catgaatgta aggatatcat gaaagacggc
    41401 tgtatcctca ttacacctga attgtatgga agtgatggat tcttcatcag tcaatttcgc
    41461 aagatatcgg attaggaagg aactgacaca tggaaatttc attattaaca gatgttggtc
    41521 agaaacgaac aaataaccaa gactatgtca accactatgt caatagagct ggacgtacca
    41581 tgattatttt agctgatggg atgggaggtc atcgtgcagg gaatatcgct agtgaaatgg
    41641 cggtcacaga cctgggtgta gcttgggttg atacccagat cgatacagtc aatgaagtgc
    41701 gtgaatggtt cgcccattac ctagaaattg aaaatcaaaa gattcaccag cttggtcagg
    41761 atgaagctta cagaggcatg ggaactactt tggaagtcct tgctattatt gataatcagg
    41821 ctatctatgc tcatattggt gattcgcgta tcggcttgat tcgtggagaa gaataccatc
    41881 agttgacgag cgatcattcc ttggttaatg aattgctcaa ggctggtcaa ttgacaccag
    41941 aagaggcaga agctcatccg caaaaaaata ttatcaccca gtctattggg caaaaagatg
    42001 aaattcagcc tgattttggg acagttatcc ttgagtcagg tgactatctc ttgctcaata
    42061 gtgacggctt gaccaacatg atttcaggca gtgagattcg tgatattgta accagtgata
    42121 ttcctttagc agataaaacg gagacacttg ttcgttttgc taacaatgca ggaggtttag
    42181 acaacattac ggttgccctt gtttttatga acgaggagga tgcagaatga tccaaatcgg
    42241 caagattttt gccggacgct atcggattgt caaacagatt ggtcgaggag gcatggcgga
    42301 tgtctaccta gccaaagact taatcttaga tggggaagaa gtggcagtga aggttctgag
    42361 gaccaactac cagacggacc cgatagctgt agctcgtttt cagcgtgaag cgagagctat
    42421 ggcagatcta gaccatcctc atatcgttcg gataacagat attggcgagg aagacggtca
    42481 acagtaccta gctatggagt atgtggctgg actggacctc aaacgctata tcaaggaaca
    42541 ttatcctctt tctaatgaag aagcagtccg tatcatggga caaattctct tggctatgcg
    42601 cttggcccat actcgaggaa ttgttcacag ggacttgaaa cctcaaaata tccttttgac
    42661 accagatggg actgccaagg tcacagactt tgggattgct gtagcctttg cagagacaag
    42721 tctgacccag actaactcga tgttgggctc agttcattac ttgtcaccag agcaggcgcg
    42781 tggttcgaag gcgactgtgc agagtgatat ctatgccatg gggattattt tctatgagat
    42841 gttgacaggc catatccctt atgacgggga tagcgcggtg accattgccc tccagcattt
    42901 ccagaaaccc ctgccgtccg ttattgcaga aaatccatct gtacctcagg ctttagaaaa
    42961 tgttattatc aaggcaactg ctaaaaagtt gaccaatcgc taccgctcgg tttcagagat
    43021 gtatgtggac ttgtctagta gcttgtccta caatcgtaga aatgaaagta agttaatctt
    43081 tgatgaaacg agcaaggcag ataccaagac cttgccgaag gtttctcaga gtaccttgac
    43141 atctattcct aaggttcaag cgcagacaga acacaaatca atcaaaaacc caagccaggc
    43201 tgtgacagag gaaacttacc aaccacaagc accgaaaaaa catagattta agatgcgtta
    43261 cctgattttg ttggccagcc ttgtattggt ggcagcttct cttatttgga tactatccag
    43321 aactcctgca accattgcca ttccagatgt ggcaggtcag acagttgcag aggccaaggc
    43381 aacgctcaaa aaagccaatt ttgagattgg tgaggagaag acagaggcta gtgaaaaggt
    43441 ggaagaaggg cggattatcc gtacagatcc tggcgctgga actggtcgaa aagaaggaac
    43501 gaaaatcaat ctggttgtct catcaggcaa acaatccttc caaattagta attatgtcgg
    43561 ccggaaatct tctgatgtta tcgcggaatt aaaagagaaa aaagttccag ataatttgat
    43621 taaaattgag gaagaagagt cgaatgagag tgaggctgga acggtcctga agcaaagtct
    43681 accagaaggt acgacctatg acttgagcaa ggcaactcaa attgttttga cagtagctaa
    43741 aaaagctacg acgattcaat tagggaacta tattggacgg aactctacag aagtaatctc
    43801 agaactcaag cagaagaagg ttcctgagaa tttgattaag atagaggaag aagagtccag
    43861 cgaaagcgaa ccaggaacga ttatgaaaca aagtccaggt gccggaacga cttatgatgt
    43921 gagtaaacct actcaaattg tcttgacagt agctaaaaaa gttacaagtg ttgccatgcc
    43981 gagttacatt ggttccagct tggagtttac taagaacaat ttgattcaaa ttgttgggat
    44041 taaggaagct aatatagaag ttgtagaagt gacgacagcg cctgcaggta gtgtagaagg
    44101 catggttgtt gaacaaagtc ctagagcagg tgaaaaggta gacctcaata agactagagt
    44161 caagatttca atctacaaac ctaaaacaac ttcagctact ccttaaaagc agatggataa
    44221 tcaaaatgag taatcaatct ttgtcatgat ttcatggcaa agattttttt tgagtccgga
    44281 tttgtgatag aatagaggga gttgataaaa ggaggaaagc atggaagaat caaaagaatt
    44341 aaatgccgtc attgatgtga ttatgctagc ggggactatt ctccttaaaa gtggctcaga
    44401 aatccatcgt gtagaagata ccatgattcg aatcgcgcat tcgcagggga ttgtggattg
    44461 caatgtcctt gccatgcctg ccgctatctt tttctctatt gaaaatacca atatttcgcg
    44521 catgaagcgc gtgacctcct cttcttataa catcgaaaaa gtctgcgatg tgaaccagat
    44581 ttctcgtcag ctagttgggg ggcagattga cttagaaaca gcctttaagc aattgacggc
    44641 cttgcaagct caaccccttc cctatactaa gttgcaggta actctggctg cgacctttag
    44701 tgctcctttc ttttcagtta tgtttagcgg aaatatctac gacgcacttg gggcaggagt
    44761 ggcgacctta tttggttttg ccttttccct ctatgtggaa aaatttatcc gaattccctt
    44821 tgtgacagcc tttgctggag cctttgtctt tgggataatt gcccagtttt gggctcgcta
    44881 cacaggtttt ccttcaacgg cagatttgat tatagctggt gcggtcatgc cgtttgtacc
    44941 aggtattgcc ttgaccaatg cggtccgtga tattatgacc aaccacataa actctggtat
    45001 gagtaagatg tttgaatccc tgctcattac cctcgcttta ggggcaggaa cttctgtcgc
    45061 cttggtattg atgaactaat atgacactaa caaccttttt attacaagca gtagcaagtt
    45121 ttcttgccat tatcactttt ttaatcgtac tcaatgtgca acggtctatg ctcttacctg
    45181 gagggatttt gggcatgact gtctggctaa tctatctctt gctcaaggaa ccgaccaatg
    45241 tcattgtagc taccttcatt gcagccatta ttggttcttg tgtcagccag attttaagta
    45301 ttctttataa gacacctgct gtggtcttta tcttggccat tttggcaccg ctggttccag
    45361 gttatctctc ctaccgaaca actgcctttt ttgtgacagg ggactataat aaagcactgg
    45421 caagtgcgac cttggttgtc atgttggctt tggtaatctc tattggaatg gctagcggaa
    45481 cagtgattct cagactgtat cattatataa aaacacatcg agtatcgtag actttacaga
    45541 aataaaagaa ttttctgaaa aatgagataa ataaattaac aacgctttct atatgtgcga
    45601 gaataccgca cttatgaaga aattgcggct gattttggta tccacgaaag caacttactc
    45661 cgtcggagcc aatgggttga agtaactctt gttcaaaggt ggtgttacga tttcaagaac
    45721 tcctctcagt tctgaagaca cggtaatgat tgatgcgacg gaagtaaaaa tcaatcgccc
    45781 taaaaaaaac aattagcgaa tgattct
//
LOCUS       DAVBEO010000010        43123 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 009
            SAMEA1678075-rid20185393.denovo.010, whole genome shotgun sequence.
ACCESSION   DAVBEO010000010 DAVBEO010000000
VERSION     DAVBEO010000010.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678075
            Sequence Read Archive: ERR226392
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 43123)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 43123)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980207.1
            Genome Coverage       :: 150x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:50:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 72 of 147
            Pseudo Genes (incomplete)         :: 72 of 147
            Pseudo Genes (internal stop)      :: 42 of 147
            Pseudo Genes (multiple problems)  :: 32 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..43123
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678075-rid20185393.denovo.010"
                     /strain="KS 009"
                     /db_xref="taxon:1313"
     gene            1..833
                     /locus_tag="VQ543_000602"
                     /pseudo
     CDS             1..833
                     /locus_tag="VQ543_000602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            complement(881..3424)
                     /locus_tag="VQ543_000603"
     CDS             complement(881..3424)
                     /locus_tag="VQ543_000603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfhO family protein"
                     /protein_id="HET2611375.1"
                     /translation="MKSFLKTYRTYFISFIIPVVIMSGVYLSQGIYWNSDNSPLLGDG
                     FHQYVIFDVALRNILHGNSSLFYTFTSGLGLNFYALSSYYLGSFLAPLVYFFDLTNMP
                     DAVYLTTLLKFGLIGLSTFFSLNKLFQSIPQTLKLALSTSYALMSFTVSQLEIKTWLD
                     VFILIPLIITGLHLLITEKKLLLYFTSLSILFIQNYYFGYMTVLFLIFWYLCQISWDF
                     KTRKSSVLDFIVISFLAGMASLIMTLPTLFDLQTHGEKLTEVTKFQTESSWYLDLFAK
                     QFIGSFDTTKYGAIPMIFVGLFPFILTILFFTLKSIKFHVKLIYVIFFAFLIASFYIE
                     ALDLFWQGMHTPNMFLHRYAWIFSTLLIYTAAEVLKRLKELKVWNFLVSLFLVVAGFL
                     ATIYLKSHYSFLTDLNILLTLEFLVVYSLLLLAVIKKFISVNLFAILISLFILVEMSL
                     NASSQMDGIAKEWGFASRSAYSRDIPAMESFSTYIGNQFTRTEKLQTQTGNDSMKFNY
                     NGISQFSSVRNRSSSSTLDKLGFKSSGTNLNLRYANNSILADSLFGIQYNISDSPIDK
                     YGFKDIYQKDNLTLYENQYSLPIAVASQSVYNDVKFNEHTLDNQASFLNQLANVNFDY
                     FSPIPYEKTENTNDLISVTSSSNEDAAIQYQIEVPENSQVYLSFINLHFSNDKQKKVD
                     ILVNGEKKTFTTDNVFSFFNLGYTKEKKTFNINVSFPGNSQVSFESPTFYRLDTKTFT
                     EAIQKIKEQPVTVSTSKNKVFATYDVQQDTSIFFTIPYDKGWSAYQDGKKIEIKQAQT
                     GFMKVDIPKGKGTITLSFIPNGFITGAICSFTSLLLFGIYNHRRKSSKA"
     gene            complement(3486..5108)
                     /locus_tag="VQ543_000604"
     CDS             complement(3486..5108)
                     /locus_tag="VQ543_000604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HET2611376.1"
                     /translation="MLTVSDVSLRFSDRKLFDDVNIKFTEGNTYGLIGANGAGKSTFL
                     KILAGDIEPTTGHISLGPDERLSVLRQNHFDYEDERAIDVVIMGNEKLYSIMKEKDAI
                     YMKEDFSDEDGVRAAELEGEFAELGGWEAESEASQLLQNLNIPEELHYQNMSELANGE
                     KVKVLLAKALFGKPDVLLLDEPTNGLDIQSITWLEDFLIDFDNTVIVVSHDRHFLNKV
                     CTHMADLDFGKIKLYVGNYDFWKESSELAAKLLADRNAKAEEKIKQLQEFVARFSANA
                     SKSRQATSRKKMLDKIELEEIVPSSRKYPFINFKAEREIGNDLLTVENLTVKIDGETI
                     LDNISFILRPDDKTALIGQNDIQTTALIRAIMGDIDYEGTVKWGVTTSQSYLPKDNSA
                     DFAGGESILDWLRQFASKEEDDNTFLRGFLGRMLFSGDEVNKPVNVLSGGEKVRVMLS
                     KLMLLKSNVLVLDDPTNHLDLESISSLNDGLKNFKESIIFASHDHEFIQTLANHIIVL
                     SKNGVIDRIDETYDEFLENAEVQAKVKELWKD"
     gene            5314..6339
                     /gene="trpS"
                     /locus_tag="VQ543_000605"
     CDS             5314..6339
                     /gene="trpS"
                     /locus_tag="VQ543_000605"
                     /EC_number="6.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000165445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan--tRNA ligase"
                     /protein_id="HET2611377.1"
                     /translation="MTKPIILTGDRPTGKLHIGHYVGSLKNRVLLQEEDKYDMFVFLA
                     DQQALTDHAKDPQTIVESIGNVALDYLAVGLDPNKSTIFIQSQIPELAELSMYYMNLV
                     SLARLERNPTVKTEISQKGFGESIPTGFLVYPIAQAADITAFKANYVPVGTDQKPMIE
                     QTREIVRSFNNAYNCDVLVEPEGIYPENERAGRLPGLDGNAKMSKSLNNGIYLADDAD
                     TLRKKVMSMYTDPDHIRVEDPGKIEGNMVFHYLDVFGRPEDAQEIADMKERYQRGGLG
                     DVKTKRYLLEILERELGPIRERRIEFAKDMGEVYNMIQKGSERAREVAGQTLSEVKGA
                     MGLHYFN"
     gene            6492..7970
                     /gene="guaB"
                     /locus_tag="VQ543_000606"
     CDS             6492..7970
                     /gene="guaB"
                     /locus_tag="VQ543_000606"
                     /EC_number="1.1.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000073411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IMP dehydrogenase"
                     /protein_id="HET2611378.1"
                     /translation="MSNWDTKFLKKGFTFDDVLLIPAESHVLPNDADLTTKLADNLTL
                     NIPIITAAMDTVTESQMAIAIARAGGLGVIHKNMSIAQQADEVRKVKRSENGVIIDPF
                     FLTPEHTIAEADELMGRYRISGVPVVETLENRKLVGILTNRDLRFISDYNQPISNHMT
                     SENLVTAPVGTDLATAESILQEHRIEKLPLVDEEGSLSGLITIKDIEKVIEFPNAAKD
                     EFGRLLVAGAVGVTSDTFERAEALFEAGADAIVIDTAHGHSAGVLRKIAEIRAHFPDR
                     TLIAGNIATAEGARALYEAGVDVVKVGIGPGSICTTRVIAGVGVPQVTAIYDAAAVAR
                     EYGKTIIADGGIKYSGDIVKALAAGGNAVMLGSMFAGTDEAPGETEIFQGRKFKTYRG
                     MGSIAAMKKGSSDRYFQGSVNEANKLVPEGIEGRVAYKGAAADIVFQMIGGIRSGMGY
                     CGAANLKELHDNAQFIEMSGAGLKESHPHDVQITNEAPNYSM"
     gene            complement(8021..9118)
                     /gene="recF"
                     /locus_tag="VQ543_000607"
     CDS             complement(8021..9118)
                     /gene="recF"
                     /locus_tag="VQ543_000607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000266665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication/repair protein RecF"
                     /protein_id="HET2611379.1"
                     /translation="MWLQHLSLKTFRNYKETKIDFNPKLNVFLGRNAQGKTNMLEAIY
                     FLALTRSHRTRTDKNLIHFDEEQLHLSGLVQKKTGSIPLEIELTQKGRVTKVNHLKQA
                     RLSDYVGHMNVVLFAPEDLQLIKGAPSIRRKFIDMELGQIKPIYLSDLTNYNHILKQR
                     NTYLKSAQKIDETFLSVLDDQLVDYGCRVMNHRLDFIKKLESFGRKKHFELSNQIEEL
                     SISYQSSVNITDKQNLSESFKIALEKSRSRDLFKKNTGVGPHRDDISFYINGMDASFG
                     SQGQHRSLVLSIKLAEIELMESITTESPILLLDDVMSELDNTRQLKLLETISQSIQTF
                     ITTTSLDHLQNLPENLSIFTIQDGKAAVNGN"
     gene            complement(9121..9489)
                     /gene="yaaA"
                     /locus_tag="VQ543_000608"
     CDS             complement(9121..9489)
                     /gene="yaaA"
                     /locus_tag="VQ543_000608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S4 domain-containing protein YaaA"
                     /protein_id="HET2611380.1"
                     /translation="MEYKLFEEFITLQALLKELGITHSGGAIKSFLSEHSVYFNRELE
                     SRRGKKLRIGDKIDIPDMNIDILLTQSTSEEQDEYQADKVEKERIAKLVKKMNKGVKK
                     DKSKPASSPKSQQAPRFPGR"
     gene            9648..10898
                     /locus_tag="VQ543_000609"
     CDS             9648..10898
                     /locus_tag="VQ543_000609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HET2611381.1"
                     /translation="MELVHGISTHFIQSKKFKTNKITVRFTAPLSLDTIAGHMLSASM
                     LETANQMYPTSQDLRRHLASLYGTDMSTNCFRRGQSHIIELTFTYVRDEFLSRKNVLT
                     SQILELVKETLFSPVVVDNGFDPALFEIEKKQLLASLAADMDDSFYFAHKELDKLFFH
                     DERLQLEYSYLRNRILAETPQSSYSCFQEFLANDRIDFFFLGDFNEVEIQNVLESFGF
                     KGRKGDVKVQYCQPYSNILQEGMVRKNVGQSILELGYHCPSKYGDEKHLPMIVMNGLL
                     GGFAHSKLFTNVRENAGLAYTISSQLDLFSGFLRMYAGIDRENRNQARKMMNNQLLDL
                     KKGYFTELELEQTKEMIRRSLLLSQDNQSSLIERAYQNALLGKSSADFKSWIAKLEQV
                     DKDAICRAANNVKLQAIYFMEGIE"
     gene            10895..12178
                     /locus_tag="VQ543_000610"
     CDS             10895..12178
                     /locus_tag="VQ543_000610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HET2611382.1"
                     /translation="MTKVVFEEKYYPAVKEMVYRTRLANGLTVALLPKKEFKEVYGSV
                     TVQFGSVDTLVTEVDGDVKQYPAGIAHFLEHKLFEREDSSDLMSAFTSLGADSNAFTS
                     FTKTNYLFSATDYFLENLDLLDELITSAHFTEASILTEQDIIQQEREMYQDDPDSCLF
                     FSTLANLYPGTPLATDIVGSEESISQINLTNLQENFTKFYKPVNMSLFLVGNFDVERV
                     QDYFESKELKDSDFQEVAREKLFLQPVKLTDSMRMEVSSPKLAIGVRGKREVSEADCY
                     RHHILLKLLFAMMFGWTSDRFQKCYESGKIDASLSLEVEITSRFHFVMLTMDTKEPVA
                     LSHQFRKAIRNFTKDLDITEEHLDIIKREMFGEFFSSMNSLEFIATQYDAFENGETIF
                     DLPKILQEITLEDVLDAGHHLIDDGDIVDFTIFPS"
     gene            12220..13041
                     /locus_tag="VQ543_000611"
     CDS             12220..13041
                     /locus_tag="VQ543_000611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HET2611383.1"
                     /translation="MRKKTIGEVLRLARINQGLSLDELQKKTEIQLDMLEAMEADDFD
                     QLPSPFYTRSFLKKYAWAVELDDQIVLDAYDSGSMITYEEVDVDEDELTGRRRSSKKK
                     KKKTSFLPLFYFILFALSILIFVTYYVWNYIQTQPEEPSLSNYSVVQSTSSTSSVPHS
                     SSSSSSSIESAISVSGEGNHVEIAYKTSKETVKLQLAVSDVTSWVSVSESELEGGVTL
                     SPKKKSAEATVATKSPVTITLGVVKGVDLTVDNQTVDLSKLTAQTGQITVTFTKN"
     gene            13052..13597
                     /gene="pgsA"
                     /locus_tag="VQ543_000612"
     CDS             13052..13597
                     /gene="pgsA"
                     /locus_tag="VQ543_000612"
                     /EC_number="2.7.8.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000712151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol--glycerol-3-phosphate
                     3-phosphatidyltransferase"
                     /protein_id="HET2611384.1"
                     /translation="MKKEQIPNLLTIGRILFIPIFIFILTIGNSIESHIVAAIIFAVA
                     SITDYLDGYLARKWNVVSNFGKFADPMADKLLVMSAFIMLIELGMAPAWIVAVIICRE
                     LAVTGLRLLLVETGGTILAAAMPGKIKTFSQMFAIIFLLLHWTLLGQVLLYVALFFTI
                     YSGYDYFKGSAYVFKGTFGSK"
     gene            13594..14421
                     /locus_tag="VQ543_000613"
     CDS             13594..14421
                     /locus_tag="VQ543_000613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HET2611385.1"
                     /translation="MKSIIDVKNLSFRYKENQNYYDVKDITFHVKRGEWLSIVGHNGS
                     GKSTTVRLIDGLLEAESGEIVIDGQRLTEENVWNIRRQIGMVFQNPDNQFVGATVEDD
                     VAFGLENQGLSRQEMKKRVEEALALVGMLDFKKREPARLSGGQKQRVAIAGVVALRPA
                     ILILDEATSMLDPEGRRELIGTVKGIRKDYDMTVISITHDLEEVAMSDRVLVMKKGEI
                     ESTSSPRELFSRNDLDQIGLDDPFANQLKKSLSQNGYDLPENYLTESELEDKLWELL"
     gene            14406..15245
                     /locus_tag="VQ543_000614"
     CDS             14406..15245
                     /locus_tag="VQ543_000614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000510406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HET2611386.1"
                     /translation="MGIALENVNFTYQEGTPLASAALSDVSLTIEDGSYTALIGHTGS
                     GKSTILQLLNGLLVPNQGSVRVFDTLITSTSKNKDIRQIRKQVGLVFQFAENQIFEET
                     VLKDVAFGPQNFGVSEEDAVKTAREKLALVGIDESLFDRSPFELSGGQMRRVAIAGIL
                     AMEPAILVLDEPTAGLDPLGRKELMTLFKKLHQSGMTIVLVTHLMDDVAEYANQVYVM
                     EKGRLVKGGKPSDVFQDVVFMEEVQLGVPKITAFCKRLADRGVSFKRLPIKIEEFKES
                     LNG"
     gene            15238..16032
                     /locus_tag="VQ543_000615"
     CDS             15238..16032
                     /locus_tag="VQ543_000615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000377903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HET2611387.1"
                     /translation="MDSMILGRYIPGDSIVHRLDPRSKLLAMMLLILIVFWANNPLTN
                     LILFIATGIFIALSGVSLSFFIQGLKSMFFLIAFTTIFQLFFISNGNVLFEFSFVRIT
                     DYALQQAGIIFCRFVLIIFFSTLLTLTTMPLSLASAVEALLAPLKRVKVPVHEIGLML
                     SMSLRFVPTLMDDTTRIMNAQKARGVDFGEGSIVQKVKAMIPILIPLFATSLKRADSL
                     AIAMEARGYQGGKGRSQYRQLKWTLKDTLTILVILVLGCCLFFLKS"
     gene            16091..16909
                     /gene="mreC"
                     /locus_tag="VQ543_000616"
     CDS             16091..16909
                     /gene="mreC"
                     /locus_tag="VQ543_000616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001078980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreC"
                     /protein_id="HET2611388.1"
                     /translation="MNRFKKSKYVIIVFVTVLLVSALLATTYSSTIVTKLGDGISLVD
                     RVVQKPFQWFDSVKSDLAHLTRTYNENESLKKQLYQLEVKSNEVESLKTENEQLRQLL
                     DMKSKLQATKTLAADVIMRSPVSWKQELTLDAGRSKGASENMLAIANGGLIGSVSKVE
                     ENSTIVNLLTNTENADKISVKIQHGSTTIYGIIIGYDKENDVLKVSQLNSNSDISAGD
                     KVTTGGLGNFNVADIPVGEVVATTHSTDYLTREVTVKLSADTHNVDVIELVGNS"
     gene            16909..17403
                     /gene="mreD"
                     /locus_tag="VQ543_000617"
     CDS             16909..17403
                     /gene="mreD"
                     /locus_tag="VQ543_000617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001249461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreD"
                     /protein_id="HET2611389.1"
                     /translation="MRQLKRVGVFLLLPFFVLIDAHISQLLGSFFPHVHLASHFLFLF
                     LLFETIEVSEYLYLVYCFVIGLVYDVYFFHLIGITTLLFILLGAFLHKLNSVILLNRW
                     TRMLAMIVLTFLFEMGSYLLAFMVGLTVDSMSIFIVYSLVPTMILNFLWITVFQFIFE
                     KYYL"
     gene            17497..18675
                     /locus_tag="VQ543_000618"
     CDS             17497..18675
                     /locus_tag="VQ543_000618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000727004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HET2611390.1"
                     /translation="MKKKILASLLLSTVMVSQVAVLTTAHAETTDDKIAAQDNKISNL
                     TAQQQEAQKQVDQIQEQVSAIQAEQSNLQAENDRLQAESKKLEGEITELSKNIVSRNQ
                     SLEKQARSAQTNGAVTSYINTIVNSKSITEAISRVAAMSEIVSANNKMLEQQKADKKA
                     ISEKQVANNDAINTVIANQQKLADDAQALTTKQAELKAAELSLAAEKATAEGEKASLL
                     EQKAAAEAEARAAAVAEAAYKEKRASQQQSVLASANTNLTAQVQAVSESAAAPVRAKV
                     RPTYSTNASSYPIGECTWGVKTLAPWAGDYWGNGAQWATSAAAAGFRTGSTPQVGAIA
                     CWNDGGYGHVAVVTAVESTTRIQVSESNYAGNRTIGNHRGWFNPTTTSEGFVTYIYAD
                     "
     gene            18899..19678
                     /gene="rpsB"
                     /locus_tag="VQ543_000619"
     CDS             18899..19678
                     /gene="rpsB"
                     /locus_tag="VQ543_000619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000268478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S2"
                     /protein_id="HET2611391.1"
                     /translation="MAVISMKQLLEAGVHFGHQTRRWNPKMAKYIFTERNGIHVIDLQ
                     QTVKYADQAYDFMRDAAANDAVVLFVGTKKQAADAVAEEAVRSGQYFINHRWLGGTLT
                     NWGTIQKRIARLKEIKRMEEDGTFEVLPKKEVALLNKQRARLEKFLGGIEDMPRIPDV
                     MYVVDPHKEQIAVKEAKKLGIPVVAMVDTNTDPDDIDVIIPANDDAIRAVKLITAKLA
                     DAIIEGRQGEDAVAVEAEFAASETQADSIEEIVEVVEGDNA"
     gene            19757..20797
                     /locus_tag="VQ543_000620"
     CDS             19757..20797
                     /locus_tag="VQ543_000620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003053075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Ts"
                     /protein_id="HET2611392.1"
                     /translation="MAEITAKLVKELREKSGAGVMDAKKALVETDGDIEKAIELLREK
                     GMAKAAKKADRVAAEGLTGVYVNGNVAAVIEVNAETDFVAKNAQFVELVNTTAKVIAE
                     GKPANNEEALALIMPSGETLEAAYVSATATIGEKISFRRFALIEKTDAQHFGAYQHNG
                     GRIGVISVVEGGDEALAKQLSMHIAAMKPTVLSYKELDEQFVKDELAQLNHVIDQDNE
                     SRAMVNKPALPHLKYGSKAQLTDDVIAQAEADIKAELAAEGKPEKIWDKIIPGKMDRF
                     MLDNTKVDQAYTLLAQVYIMDDSKTVEAYLESVNASVVEFARFEVGEGIEKAANDFEA
                     EVAATMAAALNN"
     gene            21044..21385
                     /gene="tnpB"
                     /locus_tag="VQ543_000621"
                     /pseudo
     CDS             21044..21385
                     /gene="tnpB"
                     /locus_tag="VQ543_000621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
     gene            complement(21521..21808)
                     /locus_tag="VQ543_000622"
                     /pseudo
     CDS             complement(21521..21808)
                     /locus_tag="VQ543_000622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            21799..22197
                     /locus_tag="VQ543_000623"
     CDS             21799..22197
                     /locus_tag="VQ543_000623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000841825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET2611393.1"
                     /translation="MKSPIPKAPLAHNFGSASIIAHTIHQKFNLKVPNYRQEEDWARM
                     GLPIIRKEISNWHIKTSQYYLEPLYNLLRERLLTQPLLHADETSYRVLESDSQLTYYW
                     TFLSGKAEKQGITLYHHVLIDLFISYFNPL"
     gene            complement(22394..23314)
                     /gene="cysK"
                     /locus_tag="VQ543_000624"
     CDS             complement(22394..23314)
                     /gene="cysK"
                     /locus_tag="VQ543_000624"
                     /EC_number="2.5.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000029859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase A"
                     /protein_id="HET2611394.1"
                     /translation="MSIYNNITELIGQTPIVKLNNIVPEGAADVYIKLEAFNPGSSVK
                     DRIALSMIEKAEQDGILKLGSTIVEATSGNTGIGLSWVGAAKGYKVVIVMPETMSVER
                     RKIIQAYGAELVLTPGSEGMKGAIAKAQEIAAERDGFLPLQFDNPANPEVHERTTGAE
                     ILAAFGKDGLDAFVAGVGTGGTISGVSHALKSENSNIQVFAVEADESAILSGEKPGPH
                     KIQGISAGFIPDTLDTKAYDGIVRVTSDDALALGREIGGKEGFLVGISSAAAIYGAIE
                     VAKKLGTGKKVLALAPDNGERYLSTALYEL"
     gene            complement(23599..24234)
                     /locus_tag="VQ543_000625"
     CDS             complement(23599..24234)
                     /locus_tag="VQ543_000625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000395753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YigZ family protein"
                     /protein_id="HET2611395.1"
                     /translation="MEFRTIKEDGQVQEEIKKSRFICHAKRVYSEEEARDFITAIKKE
                     HYKATHNCSAFIIGERSEIKRTSDDGEPSGTAGVPMLGVLENHNLTNVCVVVTRYFGG
                     IKLGAGGLIRAYAGSVALAVKEIGIIEIKEQAGIAIQMSYAQYQEYSNFLKEHDLMEL
                     DTNFTDQVDTMIYVDKEEKETIKAALVEFFNGKVTLTDQGLREVEVSVNLV"
     gene            24290..25588
                     /locus_tag="VQ543_000626"
     CDS             24290..25588
                     /locus_tag="VQ543_000626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000867598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HET2611396.1"
                     /translation="MKVNLDYLGRLFTENELTEEERQLAEKLPAMRKEKGKLFCQRCN
                     STILEEWYLPIGAYYCRECLLMKRVRSDQTLYYFPQEDFPKQDVLKWRGQLTPFQEKV
                     SEGLLQAVDKQKPTLVHAVTGAGKTEMIYQVVAKVINAGGAVCLASPRIDVCLELYKR
                     LQQDFSCGIALLHGESEPYFRTPLVVATTHQLLKFYQAFDLLIVDEVDAFPYVDNPTL
                     YHAVKNSVKENGLRIFLTATSTNELDKKVRLGELKRLSLPRRFHGNPLIIPKPIWLSD
                     FNRYLDKNRLSPKLKSYIEKQRKTAYPLLIFASEIKKGEQLEEILQEQFPNEKIGFVS
                     SVTEDRLEQVQAFRDGELTILISTTILERGVTFPCVDVFVIEANHRLFTKSSLIQIGG
                     RVGRSMDRPTGDLLFFHDGLNASIKKAIKEIQMMNKEAGL"
     gene            25585..26247
                     /locus_tag="VQ543_000627"
     CDS             25585..26247
                     /locus_tag="VQ543_000627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComF family protein"
                     /protein_id="HET2611397.1"
                     /translation="MKCLLCGQTMKTVLTFSSLLLLRNDDSCLCSDCDSTFERIGEEN
                     CPNCMKTELSTKCQACQFWCKEGVEVSHRAIFTYNQAMKDFFSRYKFDGDFLLRKVFA
                     SFLSEELKKYKEYQFVVIPLSPDRYANRGFNQVEGLVEAAGFEYLDLLEKREERASSS
                     KNRSERLGTELPFFIKSGVTIPKKILLIDDIYTTGATINRVKKLLEEAGAKDVKTFSL
                     VR"
     gene            26327..26875
                     /gene="raiA"
                     /locus_tag="VQ543_000628"
     CDS             26327..26875
                     /gene="raiA"
                     /locus_tag="VQ543_000628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000599099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated translation inhibitor RaiA"
                     /protein_id="HET2611398.1"
                     /translation="MIKYSIRGENLEVTEAIRDYVVSKLEKIEKYFQPEQELDARINL
                     KVYREKTAKVEVTIPLGSITLRAEDVSQDMYGSIDLVTDKIERQIRKNKTKIERKNKN
                     KVATGQLFTDALVEDSNIVQSKVVRSKQIDLKPMDLEEAILQMDLLGHDFFIYVDVED
                     QTTNVIYRREDGEIGLLEVKES"
     gene            27011..28984
                     /locus_tag="VQ543_000629"
     CDS             27011..28984
                     /locus_tag="VQ543_000629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DHH family phosphoesterase"
                     /protein_id="HET2611399.1"
                     /translation="MKKFYVSPIFPILVGLIAFGVLSTFIIFVNNNLLTVLILFLFVG
                     GYVFLFKKLRVHYTRSDVEQIQYVNHQAEESLTALLEQMPVGVMKLNLSSGEVEWFNP
                     YAELILTKEDGDFDLEAVQTIIKASVGNPSTYAKLGEKRYAVHMDASSGVLYFVDVSR
                     EQAITDELVTSRPVIGIVSVDNYDDLEDATSESDISQINSFVANFISEFSEKYMMFSR
                     RVSMDRFYLFTDYTVLEGLMNDKFSVIDAFREESKQRQLPLTLSMGFSYGDGNHDEIG
                     KVALLNLNLAEVRGGDQVVVKENDETKNPVYFGGGSAASIKRTRTRTRAMMTAISDKI
                     RSVDQVFVVGHKNLDMDALGSAVGMQLFASNVIENSYALYDEEQMSPDIERAVSFIEK
                     EGVTKLLSVKDALGMVTNRSLLILVDHSKTALTLSKEFYDLFTQTIVIDHHRRDQDFP
                     DNTVITYIESGASSASELVTELIQFQNSKKNRLSRMQASVLMAGMMLDTKNFTSRVTS
                     RTFDVASYLRTRGSDSIAIQEIAATDFEEYREVNELILQGRKLGSDVLIAEAKDTKCY
                     DTVVISKAADAMLAMSGIEASFVLAKNTQGFISISARSRSKLNVQRIMEELGGGGHFN
                     LAAAQIKDVTLSEAGEKLTEIVLNEIKEKEKEE"
     gene            28981..29433
                     /gene="rplI"
                     /locus_tag="VQ543_000630"
     CDS             28981..29433
                     /gene="rplI"
                     /locus_tag="VQ543_000630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L9"
                     /protein_id="HET2611400.1"
                     /translation="MKVIFLADVKGKGKKGEIKEVPTGYAQNFLIKKNLAKEATAQAV
                     GELRGKQKSEEKAHAEMIAEGKAIKAQLEAEETVVEFVEKVGPDGRTFGSITNKKIAE
                     ELQKQFGIKIDKRHIQVQAPIRAVGLIDVPVKIYQDITSVINLRVKEG"
     gene            29477..30829
                     /gene="dnaB"
                     /locus_tag="VQ543_000631"
     CDS             29477..30829
                     /gene="dnaB"
                     /locus_tag="VQ543_000631"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000852490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replicative DNA helicase"
                     /protein_id="HET2611401.1"
                     /translation="MAEVEELRVQPQDILAEQSVLGAIFIDESKLVFVREYIESRDFF
                     KYAHRLIFQAMVDLSDRGDAIDATTVRTILDNQGDLQNIGGLSYLVEIVNSVPTSANA
                     EYYAKIVAEKAMLRRLIAKLTESVNQAYEASQPADEIIAQAEKGLIDVSENANRSGFK
                     NIRDVLNLNFGNLEARSQQTTDITGIATGYRDLDHMTTGLHEEELIILAARPAVGKTA
                     FALNIAQNIGTKLDKTVAIFSLEMGAESLVDRMLAAEGLVESHSIRTGQLTDEEWQKY
                     TIAQGNLANASIYIDDTPGIRITEIRSRSRKLAQETGNLGLILIDYLQLITGTGRENR
                     QQEVSEISRQLKILAKELKVPVIALSQLSRGVEQRQDKRPVLSDIRESGSIEQDADIV
                     AFLYRDDYYERGGEEEEGIPNNKVEVIIEKNRSGARGTVELIFQKEYNKFSSISKREA
                     "
     gene            30831..31097
                     /locus_tag="VQ543_000632"
     CDS             30831..31097
                     /locus_tag="VQ543_000632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001278167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2611402.1"
                     /translation="MSDAFTDVAKMKKIKEEIKAHEGQVVEMTLENGRKRQKNRLGKL
                     IEVYPSLFIVEFGDVEGDKQVNVYVESFTYSDILTEKNLIHYLD"
     gene            31186..32532
                     /gene="cbpD"
                     /locus_tag="VQ543_000633"
     CDS             31186..32532
                     /gene="cbpD"
                     /locus_tag="VQ543_000633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline binding-anchored murein hydrolase CbpD"
                     /protein_id="HET2611403.1"
                     /translation="MKILPFIARGTSYYLKMSVKKLVPFLVVGLMLAAGDSVYAYSRG
                     NGSIARGDDYPAYYKNGSQEIDQWRMYSRQCTSFVAFRLSNVNGFEIPAAYGNANEWG
                     HRARREGYRVDNTPTIGSITWSTAGTYGHVAWVSNVMGDQIEIEEYNYGYTESYNKRV
                     IKANTMTGFIHFKDLDGGSVGNSQSSTSTGGTHYFKTKSAIKTEPLVSATVIDYYYPG
                     EKVHYDQILEKDGYKWLSYTAYNGSYRYVQLEAVNKNPLGNSVLSSTGGTHYFKTKSA
                     IKTEPLVSGTVIDYYYPGEKVHYDQILEKDGYKWLSYTAYNGSRRYIQLEGVTSSQNY
                     QNQSGNISSYGSNNSSTVGWKKINGSWYHFKSNGSKSTGWLKDGSSWYYLKLSGEMQT
                     GWLKENGSWYYLGSSGAMKTGWYQVSGKWYYSYSSGALAVNTTVDGYRVNSDGERV"
     regulatory      32615..32717
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            32788..33078
                     /locus_tag="VQ543_000634"
     CDS             32788..33078
                     /locus_tag="VQ543_000634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000647657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine-binding protein"
                     /protein_id="HET2611404.1"
                     /translation="MKASIALQVLPLAQGIDRIAVIDQVIAYLQTQEVTMVVTPFETV
                     LEGEFDELMRILKEALEVAGQEADNVFANVKINVGEILSIDEKLEKYTETTH"
     gene            33041..33799
                     /locus_tag="VQ543_000635"
     CDS             33041..33799
                     /locus_tag="VQ543_000635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009013602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET2611405.1"
                     /translation="MRNLKSILRRHISLLGFLGVLSIWQLAGFLKLLPKFILPTPLEI
                     LQPFVRDREFLWHHSWATLRVALLGLILGVLIACLMAVLMDSLTWLNDLIYPMMVVIQ
                     TIPTIAIAPILVLWLGYGILPKIVLIILTTTFPIIVSILDGFRHCDKDMLTLFSLMRA
                     NPWQILWHFKIPVSLPYFYAGLRVSVSYAFITTVVSEWLGGFEGLGVYMIQSKKLFQY
                     DTMFAIIILVSIISLLGMKLVDISEKYVIKWKRT"
     gene            33837..34844
                     /locus_tag="VQ543_000636"
     CDS             33837..34844
                     /locus_tag="VQ543_000636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HET2611406.1"
                     /translation="MKKTWKVFLTLVTALVAVVLVACGQGTASKDNKEAELKKVDFIL
                     DWTPNTNHTGLYVAKEKGYFKEAGVDVDLKLPPEESSSDLVINGKAPFAVYFQDYMAK
                     KLEKGAGITAVAAIVEHNTSGIISRKSDNVSSPKDLVGKKYGTWNDPTELAMLKTLVE
                     SQGGDFEKVEKVPNNDSNSITPIANGVFDTAWIYYGWDGILAKSQGVDANFMYLKDYV
                     KEFDYYSPVIIANNDYLKDNKEEARKVIQAIKKGYQYAMEHPEEAADILIKNAPELKE
                     KRDFVIESQKYLSKEYASDKEKWGQFDAARWNAFYKWDKENGILKEDLTDKGFTNEFV
                     K"
     gene            34844..35572
                     /locus_tag="VQ543_000637"
     CDS             34844..35572
                     /locus_tag="VQ543_000637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2611407.1"
                     /translation="MTEIRLEHVSYAYGQERILEDINLQVTSGEVVSILGPSGVGKTT
                     LFNLIAGILEVQSGRIVLDGEENPKGRVSYMLQKDLLLEHKTVLGNIILPLLIQKVDK
                     AEAISRADKILATFQLTAVRDKYPHELSGGMRQRVALLRTYLFGHKLFLLDEAFSALD
                     EMTKMELHAWYLEIHKQLQLTTLIITHSIEEALNLSDRIYILKNRPGQIVSEIKLDWS
                     EDEDKEVQKIAYKRQILAELGLDK"
     gene            35691..36149
                     /locus_tag="VQ543_000638"
     CDS             35691..36149
                     /locus_tag="VQ543_000638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001211265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CtsR family transcriptional regulator"
                     /protein_id="HET2611408.1"
                     /translation="MRFKNTSDHIEAYIKAILDQSGIVELQRSQLADTFQVVPSQINY
                     VIKTRFTESRGYLVESKRGGGGYIRIGRIEFSSHHEMLRELLYSIGERVSQEIYEDIL
                     QLLVEQELMTKQEMNLLESVALDRVLGEEAPVVRANMLRQVIQEVDRKGK"
     gene            36151..38583
                     /locus_tag="VQ543_000639"
     CDS             36151..38583
                     /locus_tag="VQ543_000639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001109706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HET2611409.1"
                     /translation="MNYSKALNECIESAYMVAGHFGARYLESWHLLIAMSNHSYSVAG
                     ATLNDYPYEMDRLEEVALELTETDYSQDETFMELPFSRRLQVLFDEAEYVASVVHAKV
                     LGTEHVLYAILHDGNALATRILERAGFSYEDKKDQVKIAALRRNLEERAGWTREDLKA
                     LRQRHRTVADKQNSMANMMGMPQTPSGGLEDYTHDLTEQARSGKLEPVIGRDKEISRM
                     IQILSRKTKNNPVLVGDAGVGKTALVLGLAQRIASGDVPAEMAKMRVLELDLMNVVAG
                     TRFRGDFEERMNNIIKDIEEDGQVILFIDELHTIMGSGSGIDSTLDAANILKPALARG
                     ALRTVGATTQEEYQKHIEKDAALSRRFAKVTIEEPSVADSMTILQGLKATYEKHHRVQ
                     ITDEAVETAVKMAHRYLTSRHLPDSAIDLLDEAAATVQNKVKYVKADDSDLSPADKAL
                     MDGKWKQAAQLIAKEEEVPVYKDLVTESDILTTLSRLSGIPVQKLTQTDAKKYLNLEA
                     ELHKRVIGQDQAVSSISRAIRRNQSGIRSHKRPIGSFMFLGPTGVGKTELAKALAEVL
                     FDDESALIRFDMSEYMEKFAASRLNGAPPGYVGYEEGGELTEKVRNKPYSVLLFDEVE
                     KAHPDIFNVLLQVLDDGVLTDSKGRKVDFSNTIIIMTSNLGATALRDDKTVGFGAKDI
                     RFDQENMEKRMFEELKKAYRPEFINRIDEKVVFHSLSSDHMQEVVKIMVKPLVASLAE
                     KGIDLKLQASALKLLANQGYDPEMGARPLRRTLQTEVEDKLAELLLKGDLVAGSTLKI
                     GVKAGQLKFDIA"
     gene            39225..39878
                     /gene="rr06"
                     /locus_tag="VQ543_000640"
     CDS             39225..39878
                     /gene="rr06"
                     /locus_tag="VQ543_000640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001024075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator RR06"
                     /protein_id="HET2611410.1"
                     /translation="MNILVADDEEMIREGIAAFLTEEGYHVIMAKDGQEVLEKFQDLP
                     IHLMVLDLMMPRKSGFEVLKEINQKHDIPVIVLSALGDETTQSQVFDLYADDHVTKPF
                     SLVLLVKRIKALIRRYYVIEDIWRYQDVTVDFTSYKAHYKNEEIDLKPKELLVLKCLI
                     QHKNQVLSREQILEEISKDVADLPCDRVVDVYIRTLRKKLALDCIVTVKNVGYKISL"
     gene            39875..41215
                     /gene="hk06"
                     /locus_tag="VQ543_000641"
     CDS             39875..41215
                     /gene="hk06"
                     /locus_tag="VQ543_000641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000594665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     HK06"
                     /protein_id="HET2611411.1"
                     /translation="MIKNPKLLTKSFLRSFAILGGVGLVIHIAIYLTFPFYYIQLEGE
                     KFNESARVFTEYLKTKTSDEIPSLLQSYSKSLTISAHLKRDIVDKRLPLVHDLDIKDG
                     KLSNYIVMLDMSVSTADGKQVTVQFVHGVDVYKEAKNILFLYLPYTFLVTIAFSFVFS
                     YFYTKRLLNPLFYISEVTSKMQDLDDNIRFDESRKDEVGEVGEVGKQINGMYEHLLKV
                     IHELESRNEQIVKLQNQKVSFVRGASHELKTPLASLRIILENMQHNIGDYKDHPKYIA
                     KSINKIDQMSHLLEEVLESSKFQEWTECRETLTVKPVLVDILSRYQELAHSIGVTIEN
                     QLTDATRVVMSLRALDKVLTNLISNAIKYSDKNGRVIISEQDGYLSIKNTCAPLSDQE
                     LEHLFDIFYHSQIVTDKDESSGLGLYIVNNILESYQMDYSFLPYEHGMEFKISL"
     gene            41298..41825
                     /locus_tag="VQ543_000642"
     CDS             41298..41825
                     /locus_tag="VQ543_000642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenylcysteine carboxyl methyltransferase
                     family protein"
                     /protein_id="HET2611412.1"
                     /translation="MVLAIILVTFFIRLIFLKRSIENEKRILSNGGKEFGVENTKRLT
                     MAHIVFYLSCLVEAMVHKTIFDGMGMVGLVLLIFSMLMLMLVIHLLGDIWTVKLMLVN
                     NHKYVDHILFRTVKHPNYFLNILPELIGLTLLSHAYVTFVLVFPVYAVILYRRIAEEE
                     KLLHEVIIPNGSIKR"
     gene            41904..>43123
                     /locus_tag="VQ543_000643"
     CDS             41904..>43123
                     /locus_tag="VQ543_000643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000458116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RICH domain-containing protein"
                     /protein_id="HET2611413.1"
                     /translation="MFASKSERKVHYSIRKFSIGVASVVVASLFLGGVVHAEGVRSGD
                     TPKVTSSGDEVESHLKKILSEIQTQLDRKRHAKTVALINKLQDIKRTYSYKLNVLEEK
                     PKAELTSKTKEELTAAFEQFKKDTLPTEPGKKVAEAEKKVAEAEKKAEDQKEEDRRNY
                     PTNTYKTLELEIAEFDVKVKEAELELLKEKAKKPLNEGTIKQAKEKVESKKAEATRLE
                     NIKTDRKKAEEEAKRKAAEEDKVKEKPAEQPQPAPAPQPEKPAPKPEKPAPAPKPENP
                     APKPEKPAPAPKPENPAEQPKAEKPADQQAEEDYARRSEEEYNRLTQQQPPKTEKPAQ
                     PSTPKTGWKQENGMWYFYNTDGSMATGWLQNNGSWYYLNSNGAMATGWLQNNGSWYYL
                     NANGSMATGWLQNNG"
BASE COUNT        13653 a         7069 c         9279 g        13122 t
ORIGIN      
        1 atgactgagt tttcgttaga tcttcttcta aaagccatta aactagctcg ttggacctac
       61 tactatcact tgaaacagct agataaaaca gataaggacc aagagcttaa agctgaaatt
      121 caatccatct ttatcgaaca caagggaaat tatggttatc gtcggattta tttagaacta
      181 agaaatcgtg gttatctggt aaatcataaa agagttcaac acttgatgaa gtactcaatt
      241 tacaagctaa aatgcgacag aaacgaaaat attcttctca taaaggagac gttggcaaga
      301 aggcagagaa tctcattcaa ggccaatttg aaggctctaa aacaatggaa cagtgctaca
      361 cagatgtgac agaatttgcc attccagcaa gtactcaaaa gctttactta tcaccagttt
      421 tagatggctt taatagcgaa attatcgcct ataatctttc aacttcaccc aacttagaac
      481 aagtacaaac aatgttggaa caggcattca cagagaagca ctacgagaat acgattctcc
      541 atagtgacca aggctggcaa tatcaacacg attcttatca tcagtttctt gagggtaagg
      601 gaattcaagc atctatgtca cgcaagggaa acagccaaga caacggtatg atggaatctt
      661 tctttgggat tctgaaatcg gaaatgtttt acggttatga gaagagcttt agatctttag
      721 aaaaccttga acaagctatt gtggactaca ttgattacta caacaacaaa cgaattaagg
      781 taaaactaaa agaacttagc cctgtgcaat acagaactaa atccttcgga taaattaatt
      841 gtctaacttt ttggggtcag tacattaact ggtcgatttt ttatgcctta gatgactttc
      901 gtctgtgatt atagattcca aatagtaaga gagaagtaaa ggaacagatt gctccagtaa
      961 taaaaccatt gggaatgaag gaaagtgtaa tagttccttt ccccttggga atgtcaactt
     1021 tcataaatcc agtttgagct tgtttaattt ctattttctt accatcttgg taggcagacc
     1081 aacctttgtc ataaggaatg gtgaagaaaa tagatgtatc ttgttggaca tcatatgtag
     1141 caaaaacctt gtttttagaa gttgatactg tgacaggttg ttctttaatt ttttgaattg
     1201 cctcggtgaa agttttggta tctaaacgat agaaggtagg agattcaaat gatacttgtg
     1261 aatttccagg gaaactaaca ttgatattga aagttttttt ctctttagta tatcctagat
     1321 taaagaagga gaagacatta tcagttgtaa aagtcttttt ttcaccattt acaaggatgt
     1381 caaccttctt ttgtttatcg ttagaaaagt gaaggtttat gaaagagaga taaacttggc
     1441 tgttttctgg aacttcaatt tgatactgga ttgctgcatc ttcatttgaa gaacttgtga
     1501 cactaatcaa atcattagta ttttctgttt tttcataagg tattggagaa aaataatcaa
     1561 aattgacgtt agcaagttga tttaaaaatg aggcctgatt atccaaggta tgttcattga
     1621 acttgacatc attgtaaaca gattgactag caactgcaat cggaagagag tattgatttt
     1681 catatagggt aagattatct ttttgataga tatctttaaa gccatactta tcaataggac
     1741 tgtctgagat attgtactgg ataccaaata aactatcagc caaaatacta ttatttgcat
     1801 atcggagatt gagattagtc ccagaggatt taaaaccaag tttatctaaa gtagagcttg
     1861 atgaacgatt tcgaacagat gaaaattgag agattccatt gtagttgaat ttcatactgt
     1921 catttcctgt ctgagtttgt agtttttcag tacgagtaaa ttgatttcca atatatgttg
     1981 agaaagattc catagctggg atatctcgac tataagcact tcgagaagca aatccccatt
     2041 ccttagcaat tccgtccatt tgagatgaag catttaaact catttcaacc agtataaata
     2101 aagagattag aatggcaaat agattcacag atataaactt tttgataact gcaaggagta
     2161 aaagagaata gacaaccaaa aattcaagag taagcagaat attcaaatct gttaaaaaag
     2221 aataatgcga ttttagatag atggtagcta aaaatcctgc tactacaaga aaaagcgaaa
     2281 ctaaaaaatt ccagacttta agttctttca gacgctttaa gacttctgct gctgtgtaaa
     2341 ttaacaaggt agagaaaatc caagcatagc gatgtaaaaa catgtttgga gtatgcatgc
     2401 cttgccaaaa taagtcaaga gcttctatgt aaaagcttgc aattagaaat gcaaagaata
     2461 ttacatatat gagtttcacg tgaaacttaa tagatttcag cgtaaaaaat aaaatggtca
     2521 aaataaaggg aaatagtcca acaaaaatca ttgggatggc cccatacttt gttgtgtcaa
     2581 aggaaccaat gaattgctta gcaaagagat caagatacca gctactttca gtttgaaact
     2641 ttgtaacttc agtcaatttt tccccatgtg tctgtaaatc aaatagagtg ggaagagtca
     2701 taatcaaact agccatacca gctaaaaagg agataactat gaaatcaaga acagatgatt
     2761 ttcgagtctt aaagtcccac gaaatttgac agagatacca gaaaataaga aacaatactg
     2821 tcatatatcc aaaataataa ttttgaataa ataagattga cagacttgta aagtacaata
     2881 ggagtttctt ttcagttatc agtagatgta aaccagttat aattaaagga atcaagataa
     2941 aaacatctag ccaggttttt atctctaatt gactgacagt gaaactcatc agagcatagg
     3001 aagtagataa ggctagtttt aaagtctgag ggatagattg aaacaattta ttcaaactaa
     3061 aaaaggttga cagaccaatc aatccaaatt ttaagagagt ggtcagatag acagcatctg
     3121 gcatattcgt tagatcaaaa aagtaaacta gaggcgcgag aaaactaccc aagtaataac
     3181 tagatagggc atagaagttt agccctagac cacttgtaaa ggtgtaaaac agactactat
     3241 ttccatgtag gatatttcgt aaggctacat caaaaataac gtattgatga aagccatctc
     3301 ctaatagagg agagttgtcg ctattccagt agataccttg agatagatat actccagaca
     3361 taatcactac aggaatgatg aaagaaataa aataggttcg atatgttttt aaaaatgatt
     3421 tcatgttacc tcgtagaatg atagaaaact cagttggtta acccaactga gttttgaagt
     3481 tttatttagt ctttccaaag ttctttaact tttgcttgta cttctgcatt ttctaggaat
     3541 tcatcgtagg tttcatcgat acggtcaatg acgccatttt tagataagac aatgatatgg
     3601 ttagccaaag tttgaataaa ctcgtggtca tggctggcaa agatgattga ttctttaaag
     3661 tttttcagtc catcattcaa gcttgagata gattccaagt ccaagtgatt tgttggatca
     3721 tcaagtacaa ggacatttga ttttaagagc atgagttttg aaagcatgac acgaactttt
     3781 tctccccctg acaagacatt tacaggtttg ttaacttcat ctccagagaa gagcatacgg
     3841 ccgaggaaac cacgtaggaa agtattgtca tcttcttctt tacttgcgaa ttgacgcaac
     3901 cagtcaagaa ttgattctcc tcctgcaaaa tcagctgagt tatcttttgg taggtaagat
     3961 tgactagttg taactcccca cttgacagtt ccttcatagt caatatctcc catgattgca
     4021 cgaattaatg cagtcgtttg aatatcattt tgtccaataa gtgctgtctt atcatctgga
     4081 cgcaagatga aactaatatt atccaagata gtttcaccat caatctttac agttagattt
     4141 tctactgtca agagatcatt accaatctca cgttccgctt taaagttgat aaatggatat
     4201 ttacgactag atggtacaat ctcttctagc tcaatcttat caagcatttt cttacgtgat
     4261 gttgcctgcc ttgacttaga agcattggca gagaaacgag caacgaattc ttgcaattgt
     4321 ttaatttttt cttctgcttt agcattacgg tctgctagca atttagcagc aagctcagaa
     4381 gattccttcc agaagtcgta gtttccgaca tagagtttga tttttccaaa gtcaaggtcg
     4441 gccatgtgag tacaaacttt gtttaagaag tgacggtcgt gggatactac gataactgtg
     4501 ttatcaaagt caatcaagaa gtcttctaac caagtaatcg attggatatc caaaccgtta
     4561 gtaggctcgt ccaagagaag aacatctggt ttaccaaaaa gtgctttggc gaggagaacc
     4621 tttacttttt caccgttggc caattcgctc atgttttggt agtgtaattc ttctggaatg
     4681 tttaggtttt gaagtagttg agaggcttca ctctctgctt cccaacctcc aagttcggca
     4741 aactctcctt cgagttcggc agcacgaacc ccgtcctcgt ctgagaaatc ttccttcatg
     4801 tagatagcat ctttctcttt catgatgcta taaagttttt catttcccat gataacgaca
     4861 tcaatggcac gttcatcttc gtagtcaaag tgattttgac gaagaacaga gagacgttca
     4921 tctggaccaa gagagatgtg accagtagta ggttcgatat ctccagctaa aatttttaaa
     4981 aaggttgatt ttccggcacc attagcaccg attaatccgt aagtatttcc ttctgtaaat
     5041 ttgatattga catcatcaaa aagtttgcga tcactaaaac gtagtgaaac atcagatact
     5101 gtaagcaatg tttttctcct atatgtgtaa tatatttatt ctactagaaa atacagaaat
     5161 attcaaattt ttatttgtca attttgtgta aattatattt acagtatcct ttacacaaat
     5221 ctgtaaaaag caaggctgat ttattttgat aaattacggt tatttcatta aaaaaatgct
     5281 ataattgaaa ggactatatc gaaggagaac aaaatgacta aacccattat tttaacagga
     5341 gaccgtccaa caggaaaatt gcatattgga cattatgttg gaagtctcaa aaatcgagta
     5401 ttattacagg aagaggataa gtatgatatg tttgtgttct tggctgacca acaagccttg
     5461 acagatcatg ccaaagatcc tcaaaccatt gtagagtcta tcggaaatgt ggctttggat
     5521 tatcttgcag ttggattgga tccaaataag tcaactattt ttattcaaag ccagattcca
     5581 gagttggctg agttgtctat gtattatatg aatctagttt cgttagcacg tttggagcga
     5641 aatccaacag tcaagacaga gatttctcag aaaggatttg gagaaagcat tccgacagga
     5701 ttcttggtct atccaatcgc tcaagcagct gatatcacag ctttcaaggc taattatgtt
     5761 cctgttggga cagatcagaa accaatgatt gagcaaactc gtgaaattgt tcgttctttt
     5821 aacaatgcat ataactgtga tgtcttggta gagccggaag gtatttatcc agaaaatgag
     5881 agagcagggc gtttgcctgg tttagatgga aatgctaaaa tgtctaaatc actaaataat
     5941 ggtatttatt tagctgatga tgcggatact ttgcgtaaaa aagtaatgag tatgtataca
     6001 gatccagatc atatccgcgt tgaggatcca ggtaagattg agggaaatat ggttttccat
     6061 tatctagatg tttttggtcg tccagaagat gctcaagaaa ttgctgatat gaaagaacgt
     6121 tatcaacgag gtggtcttgg tgatgtgaag accaagcgtt atctacttga aatattagaa
     6181 cgtgaactgg gtcctattcg tgagcgccgt attgaatttg ctaaggatat gggagaagtt
     6241 tataatatga ttcaaaaagg tagtgaaaga gcgcgtgaag ttgcgggtca aaccctatct
     6301 gaggtaaaag gggcaatggg acttcattac tttaactaag tttattttac aagaaactat
     6361 catttctatc tcgaagaaaa gatagttttt ttatttaccc ctgtaacatt tgacaaattt
     6421 ttatagaatg gtatgataga tacaatataa aaagagtcaa gctcaaaaag aaagaaaaga
     6481 ggaaacttcg aatgtctaat tgggacacta aatttttgaa aaaaggtttt acctttgatg
     6541 atgtattgct tattccagct gaaagtcatg tgttgcctaa cgatgcagat ttaacaacta
     6601 aattggcaga taatttgact ttaaatatcc caattattac cgctgccatg gacacagtta
     6661 cagagagtca aatggccatt gctattgctc gtgcaggcgg tctcggagtt atccataaaa
     6721 acatgtcaat tgctcaacaa gcagacgagg ttcgtaaggt aaaacgttct gaaaatggag
     6781 ttattattga tccgttcttc ttgacgcctg aacatacaat tgctgaagca gatgagctta
     6841 tgggtcgtta ccgcatcagt ggtgttccag ttgttgaaac acttgaaaat cgtaaattgg
     6901 ttggtatttt gacaaaccga gatcttcgtt ttatttcaga ttataatcaa ccaatttcaa
     6961 accatatgac tagtgaaaat cttgttactg ctcctgtggg tacggatctt gcaacggctg
     7021 agagtattct tcaagagcat cgtattgaaa aacttccgtt ggtcgatgaa gaaggcagtc
     7081 tttctggttt gatcactatc aaagatattg aaaaagttat tgagtttcca aatgcggcta
     7141 aagatgagtt tggtcgtctt ctagttgcag gtgcagtagg tgttacttca gatacatttg
     7201 aacgtgcaga ggctcttttt gaggcaggag cggatgcgat tgttattgat actgcacatg
     7261 gtcattctgc aggtgtcttg cgtaaaattg ccgagattcg tgctcatttc ccagatcgga
     7321 ctttgattgc tggaaatatt gctactgctg aaggtgcacg tgccctttat gaagcgggtg
     7381 tagacgttgt taaggttggt attggaccag gttctatctg tactactcgt gtgattgctg
     7441 gtgttggtgt tccgcaagta acagctatct acgatgctgc agctgttgcg cgcgaatatg
     7501 gtaaaacgat tattgctgac ggtgggatca agtattctgg agatattgta aaagcacttg
     7561 ctgcaggtgg aaatgctgtt atgcttggat ctatgtttgc tggaactgat gaagctccag
     7621 gcgaaactga aatcttccaa ggacgtaaat tcaagactta ccgtggtatg ggatcaattg
     7681 ctgctatgaa gaaaggttca agcgaccgtt atttccaagg ttctgtcaat gaagcaaaca
     7741 agcttgttcc agaaggaatt gaaggtcgtg ttgcttataa aggagcggca gctgatattg
     7801 ttttccaaat gattggtggt attcgctctg gtatgggtta ctgtggtgca gctaacctta
     7861 aagaactaca cgataatgct caatttattg aaatgtctgg tgctggtttg aaagaaagcc
     7921 atcctcatga tgtgcaaatt actaatgagg caccaaatta ttctatgtaa aaaacaatga
     7981 aaagaactcc agtgaaaaca ggagttcttt tacaatgttg tcaatttcca tttacagcag
     8041 ctttaccatc ctgaatagtg aagatactta gattttctgg cagattttga agatggtcta
     8101 agcttgttgt tgtgataaag gtttggattg attgagaaat cgtttctaat aattttaact
     8161 gtctagtgtt gtcaagttca ctcatcacat cgtcaagcag taatatagga gattctgtgg
     8221 taatgctttc cattaattcg atttctgcta attttatcga gaggacgaga ctacgatgtt
     8281 gaccttggct tccgaaacta gcatccatcc catttatata aaaagaaatg tcatctcgat
     8341 gaggaccgac accagtattc tttttaaata aatctctgga tctacttttt tctaaagcaa
     8401 ttttgaaaga ttcggataag ttttgtttgt cagttatatt gacagaagat tgataggata
     8461 ttgacaactc ttcgatctga ttagagagtt caaaatgttt cttacgccca aatgattcta
     8521 gtttttttat gaaatctaag cggtgattca ttacacgaca tccataatca actagctgat
     8581 catctaacac agaaaggaat gtttcatcta ttttttgagc tgattttagg taagtgtttc
     8641 tttgctttag gatgtggtta taattggtta agtcagataa atagattggc ttaatttgcc
     8701 caagttccat atcaatgaat tttcgtcgaa tcgaaggtgc tcctttaatt agttgtaaat
     8761 cttcaggagc aaataagaca acattcatgt gtcctacata atctgaaagg cgtgcctgtt
     8821 ttaagtgatt aacttttgtt acacggcctt tttgtgttag ttcgatttct aggggaatgg
     8881 atccagtttt tttctgaacg agacctgaaa gatgaagttg ttcctcatca aaatgaatga
     8941 gatttttatc tgttcgagtt cgatgactac gcgttaaggc taaaaaatag atagcctcta
     9001 acatgtttgt ttttccttgt gcattacgtc ccaaaaagac attcaattta ggattaaagt
     9061 ctattttcgt ttctttgtaa ttacgaaaag tcttgagaga tagatgttgt agccacatga
     9121 ttatctacca gggaatcgtg gagcttgttg gcttttaggt gatgaagcag gtttcgattt
     9181 gtctttttta actcccttat tcatcttttt gacaagttta gcgatccgtt ctttttcaac
     9241 tttatcagct tggtattcat cttgttcttc agaagtagat tgtgtcaaca agatgtcaat
     9301 gttcatgtca gggatgtcaa ttttatcgcc aatacgaagt tttttaccac gacgactctc
     9361 taattcccta ttaaagtaaa cagaatgttc agagagaaat gatttaatag ctcctccgct
     9421 atgtgtaatt ccaagttctt tgagtagtgc ttggagggta ataaattctt caaataattt
     9481 gtattccata attcacctca atctttggta ttataccata ttttcctaaa aatagtgaga
     9541 gatacagcga gaaatgtaag cgatttttat ttcaaaagtg ttacagggaa caagaaaatt
     9601 tcaggttttc gtgatataat agaagtctgt atataaggag ataaatcatg gagttagtgc
     9661 atggaatttc aacacatttt atccaatcaa aaaagtttaa aacaaacaaa attaccgtgc
     9721 gttttaccgc tccattatcc cttgatacga ttgcaggtca catgttgagt gcaagtatgc
     9781 tagagactgc taatcagatg taccccactt ctcaagattt gaggagacac ttggccagtc
     9841 tatacggtac agatatgtca accaattgtt tcagaagagg gcaaagccac attatagaat
     9901 tgacatttac ctatgttcgt gatgagtttt taagtaggaa aaacgtgcta acttctcaga
     9961 ttttggaact tgtaaaagaa actctttttt cacccgtagt agttgataat gggtttgatc
    10021 cggccttatt tgaaattgag aaaaaacaat tgctagcaag tttagcagct gatatggatg
    10081 attcttttta ttttgcacat aaagaattgg ataaattgtt ttttcatgat gaacgtcttc
    10141 aattggaata tagttattta cgaaatcgta ttttagctga aactccacaa agttcttatt
    10201 cttgtttcca agaattttta gccaatgatc gaatagattt ctttttccta ggtgatttta
    10261 atgaggttga aattcaaaat gtattagaat catttggctt taaaggtcga aaaggagatg
    10321 tgaaggttca gtattgtcaa ccttattcta atatccttca ggaaggtatg gttcggaaaa
    10381 atgtgggaca atccattttg gaattaggtt atcattgccc ttctaaatat ggtgatgaga
    10441 aacatttacc catgattgta atgaatggtt tacttggtgg atttgctcac tctaaacttt
    10501 ttacaaatgt ccgtgaaaat gctggattag cttatactat ttcaagtcag ctcgatttat
    10561 ttagtggatt cttgaggatg tatgctggta ttgaccgaga aaatcgtaac caggctcgta
    10621 aaatgatgaa taatcaactg cttgatttaa aaaaaggtta ttttacagag cttgagttag
    10681 agcagaccaa ggaaatgatt cgtcggtctt tgttactttc tcaagataac caatcttcat
    10741 tgattgaacg tgcttatcaa aatgccttac ttggaaaatc ttcagcagat tttaaaagtt
    10801 ggattgcaaa actcgagcaa gttgacaaag atgctatttg tagagcagct aacaatgtga
    10861 aactacaagc gatttacttt atggaaggaa tagaatgaca aaggttgttt ttgaagaaaa
    10921 atactatcca gctgtaaaag aaatggttta tcgaactcgt ttggcaaatg gattgacagt
    10981 agctcttttg cctaaaaagg aatttaaaga ggtttacggg agtgtaactg tacagtttgg
    11041 ttcggtagat acgcttgtca cagaagttga tggagatgta aaacaatatc ctgcaggaat
    11101 tgctcatttt cttgaacata aattatttga aagagaagat tctagcgatt tgatgtcggc
    11161 ttttacgagt ctaggtgcag atagtaatgc ctttacaagc tttacaaaaa caaactatct
    11221 tttttcagca acggattatt ttttagaaaa tttagattta cttgatgaat tgataacatc
    11281 agcacacttt actgaagctt ccattctgac agagcaggat attattcagc aagaacgaga
    11341 aatgtaccaa gatgatccag attcgtgttt attcttttca actttagcga atttgtatcc
    11401 tggtacacct ttagcaactg atatagttgg aagtgaggag tccatttccc aaatcaatct
    11461 aactaatttg caagaaaatt ttacaaagtt ttacaaacct gtaaacatgt ctctgttttt
    11521 agttggtaat tttgatgtgg agcgagtaca ggactatttt gaaagcaaag aactgaaaga
    11581 ttcagatttt caggaagtag caagagaaaa gttgttttta cagcctgtaa agctaacaga
    11641 tagtatgaga atggaagtat cttctcccaa actagcgatt ggagttagag gtaagcgaga
    11701 agtttctgaa gcggattgct atcgacatca tattttatta aaattattgt ttgcaatgat
    11761 gtttggttgg acttcggatc gttttcaaaa atgttatgaa tcaggtaaaa ttgatgcgtc
    11821 cttatctctg gaagttgaaa taacaagtcg ctttcatttt gtcatgttga caatggatac
    11881 gaaagagcca gttgctttgt ctcatcaatt taggaaggct attcgtaatt ttacaaagga
    11941 tttagatatt acagaggaac atttagatat tatcaaaaga gagatgtttg gcgaattttt
    12001 cagtagcatg aactctcttg aatttattgc aacgcaatat gatgcttttg aaaatggtga
    12061 gacaattttt gatttgccga aaattttaca ggaaattact ttagaggatg tccttgatgc
    12121 tggacatcat ttaatagatg atggtgacat agttgatttt acaatatttc catcgtagta
    12181 acctatcata atagacacta gaaagaaggg atgacaagta tgagaaaaaa aacaattgga
    12241 gaggttttac gattagctag aatcaatcag ggattgagtt tagatgaatt gcagaaaaag
    12301 acagaaatcc agttagatat gttggaagca atggaagcag acgatttcga tcaacttcca
    12361 agtccttttt acacgcgttc tttcttgaaa aaatatgcat gggctgttga gttagatgac
    12421 caaattgttt tggatgctta tgattctggg agtatgatta cttatgagga agtagatgtt
    12481 gatgaagatg agttgacagg tcgtagacgt tcaagtaaga aaaagaagaa aaaaacatca
    12541 tttttacctt tattttattt tatccttttt gctttatcga ttttaatttt tgtgacttat
    12601 tatgtttgga actatattca aactcaacca gaggagcctt ctctttctaa ttacagtgtg
    12661 gttcaatcaa caagttcaac tagctctgtt ccccactcct caagtagtag ttcttctagt
    12721 atagaatcag ctataagtgt atcaggcgaa ggaaatcatg tagaaatcgc ttataagaca
    12781 agtaaggaaa cagttaaatt gcaattggca gtttcagatg ttacaagttg ggtcagtgtt
    12841 tcagaaagcg aacttgaggg cggtgtaacc ttatcgccaa agaagaaaag tgcagaagca
    12901 acagttgcaa ctaaaagtcc tgtaacaatt acgttaggtg ttgtaaaagg tgttgatttg
    12961 acagtagata atcagactgt tgatttatcg aaattaacag ctcagactgg acaaatcact
    13021 gtaaccttta ctaaaaatta aggaaaaacg aatgaaaaaa gaacaaattc ccaatctctt
    13081 aacaataggt cgaattctct ttatacctat ttttatcttt attttaacga taggaaattc
    13141 gatagagagt catatagttg cagctattat ctttgctgtt gccagtatta ccgactattt
    13201 agatggatat ttagctcgta aatggaatgt ggtcagtaat tttggtaaat ttgcagatcc
    13261 tatggcggat aagttactag ttatgtcggc ttttattatg ttgattgagt taggtatggc
    13321 tccggcttgg attgttgcag tgattatatg tcgtgagtta gctgtgacag gtttaaggct
    13381 tttattggtt gaaactggtg gaacaatttt agcagcagca atgcctggaa aaattaaaac
    13441 ttttagtcag atgtttgcta ttattttctt gctattacat tggactttgc ttggtcaagt
    13501 tctactttat gtagccttat ttttcactat ctactctggc tatgactatt ttaagggtag
    13561 tgcctatgta tttaaaggga catttggttc gaaatgaaat caataattga tgtaaaaaat
    13621 ctttcttttc gctataaaga aaatcagaac tactacgatg tgaaggatat tacgtttcac
    13681 gtgaaacgtg gagaatggct ttcgattgta gggcataatg gtagtggtaa atcaacgacg
    13741 gttcgattaa ttgatggctt actggaagca gaatccggag agattgtaat tgatggccaa
    13801 cgtttgactg aggaaaatgt ttggaatata cgtcgtcaaa tcggtatggt ttttcaaaat
    13861 ccagacaatc aatttgttgg agcgactgtt gaagatgatg ttgcttttgg tttggaaaat
    13921 cagggacttt ctcgtcaaga aatgaaaaag agagtggaag aagctctggc tttagttggc
    13981 atgttggact ttaaaaagag agagccagcg cgtctatcag gtggtcaaaa gcaacgtgtg
    14041 gccattgcag gtgttgtagc cctaagacca gctattttaa tcttagatga agcaacgagt
    14101 atgttggatc ctgaggggcg tagagaactt attgggacag taaaaggaat tcgaaaagac
    14161 tatgatatga cggtcatttc tattacccat gatttggaag aagtcgccat gagtgatcgc
    14221 gtattggtca tgaaaaaagg ggaaattgaa tcaactagta gtccaaggga gcttttctct
    14281 cgaaatgatt tagatcaaat tggattagac gatccttttg ctaatcaatt aaaaaaatct
    14341 ttgagccaga atggctatga tttacctgaa aattatttga cagaaagtga gctagaggat
    14401 aagctatggg aattgctcta gaaaatgtga attttacata tcaagaaggt actcccttag
    14461 cttcagcagc tttgtcggat gtttctttga cgattgaaga tggctcttat acagctttaa
    14521 ttgggcacac aggtagtggt aaatcaacta ttttacaact cttaaatggt ttattggtgc
    14581 caaatcaagg gagtgtgagg gtttttgata ccttaatcac ctcgacttct aaaaataaag
    14641 atattcgtca aattagaaaa caggttggct tggtatttca gtttgctgaa aatcagattt
    14701 ttgaagaaac ggttttgaag gacgttgctt ttggaccgca aaattttgga gtttctgaag
    14761 aagatgctgt gaagactgcg cgtgagaaac tggctctggt tggaattgat gaatcacttt
    14821 ttgatcgtag tccgtttgag ctgtcagggg gacaaatgag acgtgttgcc attgcaggca
    14881 tacttgccat ggagccagct atattagtct tagatgagcc aacagctggt ctagatcctc
    14941 tagggagaaa agagttgatg accctgttca aaaaactcca ccagtcaggg atgaccatcg
    15001 tcttggtaac gcatttgatg gatgatgttg ctgaatatgc gaatcaagtc tatgtaatgg
    15061 aaaagggacg tttagtaaag gggggcaaac caagtgatgt ctttcaagac gttgttttta
    15121 tggaagaagt tcagttggga gtacctaaaa ttacggcctt ttgtaaacga ttggctgata
    15181 gaggcgtgtc atttaaacga ttaccgatta agatagagga gttcaaggag tcgctaaatg
    15241 gatagtatga ttttagggcg ttatatccca ggggattcga ttgttcaccg attggatcca
    15301 cgtagcaaat tgcttgctat gatgctactg attttgattg tgttttgggc taataacccc
    15361 ttgacgaatc tgattctttt tatagcgaca gggatattta ttgccttgtc aggagtatct
    15421 ctttcatttt ttattcaggg cttgaagtct atgtttttct tgattgcctt cacaactatt
    15481 tttcaactat ttttcatttc taatgggaat gttttatttg agttttcgtt tgtgagaatc
    15541 acggattatg ctttgcaaca agctgggatt attttttgtc gctttgtatt gattattttc
    15601 ttttcaactt tgttaacctt aacaaccatg cctttaagtt tggcatcagc tgtcgaagct
    15661 ttattagcac ctttaaagcg tgtgaaagtt ccagttcatg aaattggatt gatgctgtct
    15721 atgagtttgc gttttgtccc aaccttgatg gatgatacga ctcggattat gaatgcacag
    15781 aaagctcgtg gagtggattt tggagaagga agcatcgttc aaaaagtaaa ggcgatgatt
    15841 cccattttga ttcctctttt tgcgacaagt ttaaaacgtg cagattcctt ggctatcgct
    15901 atggaagcgc gtggctatca gggtggaaaa ggcagaagtc aataccgaca attgaaatgg
    15961 actctaaagg atacgctgac cattcttgtt attctcgtac ttggttgttg tttatttttc
    16021 ttaaaatctt agtagctttc aggaattgat aaaaagttac tgtaacagtt tttgatataa
    16081 aggtaggaat atgaaccgtt ttaaaaaatc aaaatatgtc attattgttt ttgtcactgt
    16141 tctgcttgtg tcagctctct tagcgacgac ttattcaagt acaattgtga caaaattagg
    16201 agatggaatc tcattggttg atagagttgt acaaaaacct tttcagtggt ttgattctgt
    16261 caaatcagat ttggctcatt tgacacgaac atataatgaa aatgaaagtt tgaagaaaca
    16321 gctttaccaa ttagaagtta aatcaaatga ggtggaaagt ttaaagacag aaaatgaaca
    16381 actgcgccaa ttgcttgata tgaagtctaa attgcaagcc acaaagactt tagcagcaga
    16441 tgttattatg cgttctccgg tatcttggaa gcaggagttg accttagatg caggtagatc
    16501 aaaaggtgct tctgagaaca tgttagctat tgcaaatggt ggcttgattg ggagtgtttc
    16561 aaaagtagag gagaactcta ctatagtcaa ccttctgaca aatacggaaa atgctgataa
    16621 gatttctgtt aaaattcaac atggctctac tacaatttat ggaattatta ttggctatga
    16681 caaggaaaat gacgttctta aagttagcca attaaatagt aatagcgata ttagtgcggg
    16741 agataaggtg actactggtg gattaggaaa ctttaacgtt gctgatattc ctgttggtga
    16801 agtggttgcc acaacgcata gtacagacta tttgacacga gaagtaactg ttaaattgag
    16861 tgcagatact cataatgtag atgtgataga attagtgggg aattcataat gagacagttg
    16921 aagcgagttg gagtattttt attgcttcct ttctttgttc taattgacgc ccatattagc
    16981 cagcttctgg gctcattttt cccccatgta catttggcta gtcattttct ttttctattt
    17041 ctcttatttg agacgataga agtatcagag tatctctacc tagtctattg ttttgttata
    17101 ggcttggttt atgatgttta ctttttccat ctaataggga ttacaactct cttatttatc
    17161 ttattgggag ccttccttca taaattgaat agtgttattt tgttgaatcg ttggacaaga
    17221 atgctagcta tgattgtact gacattcctg tttgaaatgg gtagttatct tttggctttt
    17281 atggtagggt tgacagtaga tagcatgtcg atttttatag tctatagctt ggtaccgacg
    17341 atgattttaa attttttatg gattactgtt tttcaattta tttttgaaaa atattatcta
    17401 taagaacgac atataaatgt aacaaaggcg taatatttat taggcctttt tttggtatac
    17461 tagtattgtc tttaaaagaa ggagtatcta cgtaatatga agaaaaaaat cttagcgtca
    17521 cttttattaa gtacagtaat ggtttctcaa gtagctgttt taacaactgc gcatgcagaa
    17581 acgactgatg acaaaattgc tgctcaagat aataaaatta gtaacttaac agcacaacaa
    17641 caagaagccc aaaaacaagt tgaccaaatt caggagcaag tatcagctat tcaagctgag
    17701 cagtctaact tgcaagctga aaatgataga ttacaagcag aatctaagaa actcgagggt
    17761 gagattacag aactttctaa aaacattgtt tctcgtaacc aatcgttgga aaaacaagct
    17821 cgtagtgctc aaacaaatgg agccgtaact agctatatca ataccattgt aaactcaaaa
    17881 tcaattacag aagctatttc acgtgttgct gcaatgagtg aaatcgtatc tgcaaacaac
    17941 aaaatgttag aacaacaaaa ggcagataaa aaagctattt ctgaaaaaca agtagcaaat
    18001 aatgatgcta tcaatactgt aattgctaat caacaaaaat tggctgatga tgctcaagca
    18061 ttgactacga aacaggcaga actaaaagct gctgaattaa gtcttgctgc tgagaaagcg
    18121 acagctgaag gggaaaaagc aagtctatta gagcaaaaag cagcagctga ggcagaggct
    18181 cgtgcagctg cggtggcaga agcagcttat aaagaaaaac gagctagcca acaacaatca
    18241 gtacttgctt cagcaaacac taacttaaca gctcaagtgc aagcagtatc tgaatctgca
    18301 gcagcacctg tccgtgcaaa agttcgtcca acatacagta caaacgcttc aagttatcca
    18361 attggagaat gtacatgggg agtaaaaaca ttggcacctt gggctggaga ctactggggt
    18421 aatggagcac agtgggctac aagtgcagca gcagcaggtt tccgtacagg ttcaacacct
    18481 caagttggag caattgcatg ttggaatgat ggtggatatg gtcacgtagc ggttgttaca
    18541 gctgttgaat caacaacacg tatccaagta tcagaatcaa attatgcagg taatcgtaca
    18601 attggaaatc accgtggatg gttcaatcca acaacaactt ctgaaggttt tgttacatat
    18661 atttatgcag attaatttac agagggactc gaatagagcc ctcttttcag gttttaccgt
    18721 gacaatccct attaaaaatt atatcaaaat agcttgaaaa tattggaaaa gtatggtaaa
    18781 atgaaaattg tcgtgtgaac gataatactc attcttgatg aattgtgaag cagttgccct
    18841 tgggtcgttt tgcgagttga agtcaagaag aggaaaaaaa caaaaaggag aaatactcat
    18901 ggcagtaatt tcaatgaaac aacttcttga ggctggtgta cactttggtc accaaactcg
    18961 tcgctggaat cctaagatgg ctaagtacat ctttactgaa cgtaacggaa tccatgttat
    19021 cgacttgcaa caaactgtaa aatacgctga ccaagcatac gacttcatgc gtgatgcagc
    19081 agctaacgat gcagttgtat tgttcgttgg tactaagaaa caagcagctg atgcagttgc
    19141 tgaagaagca gtacgttcag gtcaatactt catcaaccac cgttggttgg gtggaactct
    19201 tacaaactgg ggaacaatcc aaaaacgtat cgctcgtttg aaagaaatta aacgtatgga
    19261 agaagatgga actttcgaag ttcttcctaa gaaagaagtt gcacttctta acaaacaacg
    19321 tgcgcgtctt gaaaaattct tgggcggtat cgaagatatg cctcgtatcc cagatgtgat
    19381 gtacgtagtt gacccacata aagagcaaat cgctgttaaa gaagctaaaa aattgggaat
    19441 cccagttgta gcgatggttg acaccaatac tgatccagat gatatcgatg taatcatccc
    19501 agctaacgat gacgctatcc gtgctgttaa attgatcaca gctaaattgg ctgacgctat
    19561 tatcgaagga cgtcaaggtg aggatgcagt agcagttgaa gcagaatttg cagcttcaga
    19621 aactcaagca gattcaattg aagaaatcgt tgaagttgta gaaggcgaca acgcttaatt
    19681 tatacaaata gtaattacct aggagggcgg ggcttagccc ggctctccta ttttcaaaaa
    19741 atataggaga attaaaatgg cagaaattac agctaaactt gtaaaagagt tgcgtgaaaa
    19801 atctggtgcc ggtgttatgg acgctaaaaa agcgcttgta gaaacagacg gtgacatcga
    19861 aaaagcgatt gaattgcttc gtgaaaaagg tatggctaag gcagctaaga aagctgaccg
    19921 tgttgctgca gaaggtttga ctggtgttta tgttaacggt aatgttgcag cagttattga
    19981 agtaaacgct gaaactgact tcgttgcaaa aaacgctcaa ttcgttgaat tggtaaatac
    20041 tacagctaaa gtcattgctg aaggaaaacc tgctaacaac gaagaagctc ttgctttgat
    20101 aatgccttca ggtgaaactc ttgaagctgc atacgtatct gcaacagcaa ctatcggaga
    20161 gaaaatctca ttccgtcgct ttgcattgat tgaaaaaaca gacgcacaac actttggagc
    20221 ataccaacat aacggtggac gtatcggtgt tatttcagtt gttgaaggtg gagacgaagc
    20281 acttgctaaa caattgtcaa tgcacatcgc agcgatgaaa ccaacagttc tttcttacaa
    20341 agaattggat gagcaattcg ttaaagatga gttggcacaa ttgaatcacg ttatcgacca
    20401 agacaacgaa agccgtgcaa tggttaataa accagctctt ccacacttga agtatggatc
    20461 aaaagctcaa ttaactgatg atgttattgc tcaagctgaa gctgacatca aagctgaatt
    20521 ggctgcagaa ggcaaaccag aaaaaatctg ggacaaaatt attccaggta aaatggatcg
    20581 cttcatgctt gataacacta aagttgacca agcttacaca cttcttgcac aagtttacat
    20641 catggatgac agcaagacag ttgaagcata ccttgaatca gttaacgctt cggtagttga
    20701 gtttgctcgc tttgaagttg gtgaaggtat cgagaaagct gcaaacgact tcgaagctga
    20761 agttgcagct acaatggcag cagccttgaa taactaataa tagaaaggaa gcaaattgct
    20821 tccttttttg tatagggctt agatttttcc tgaaattgtt ttttccccag tctcactcga
    20881 ttagaataat taaaacaaaa agccctataa taagggctaa gtgcatttag gagactatac
    20941 ttcaaattca tagtaagcgc gttcataaca aggtatctat cctaattccc caacttccag
    21001 tatactagat aaaaaataat tatcggagta aaggtattgt actatgataa ttcaactaag
    21061 tgatttaggt caagttcacc ttgtttgtgg caagacagat atgaggtagg gaatagactc
    21121 attagcctat gtagttaaaa cccactttga attggattct ttctccggtc aagtctttct
    21181 cttttgtggt gaacgtaaag accgctttaa agccctttac tgggatggtc aaggattttg
    21241 gctactatat aaacgctttg agaacggaaa actgacttgg ctaagtacag aaaaggatgt
    21301 caaagctctc gcacctgaac aagtagattg gcttatgaag ggcttttcta tcactccaaa
    21361 atatagtata ttgaaactag aatagtacac ctctgcttct aaaacattgt tagaaatcga
    21421 tttgactgtc ctgatcgatt tatcctgttc ttatttcatt ttactataaa tctatcagaa
    21481 agttgtgatt tctattgaaa tgaggacttt ctttttacac tcatctgctt tcaaaaagca
    21541 ttctagtccg tctccgatta acgatggact ttatcacctc cttctccagt ccttgtatga
    21601 catcttccaa agttcgaaag gctttattct taaatccacg tttacgaatc tctttccaca
    21661 cttgttcaat ggggttcatc tctggtgtgt atggaggaat aaatgcaaag ccaatattag
    21721 tcggaatctt taaggtactt gatttatgcc atatagcatt gtccataacg agtaaaagat
    21781 aatcatctgg ataagcttgt gaaatctcct attcctaaag cccctttagc gcataacttt
    21841 ggctcagctt ctattatcgc tcacaccatc catcagaagt ttaatctgaa ggtacccaat
    21901 tatcgccaag aagaagattg ggctaggatg ggtttaccaa tcatacgtaa ggaaatctct
    21961 aattggcata tcaagacgag tcaatactat ttggagcccc tttataacct cttgcgagag
    22021 agactattga ctcagccctt acttcatgcg gatgaaactt cttatagggt gctagagagt
    22081 gatagtcagc tgacttacta ctggactttt ttgtctggga aagctgagaa acaagggatt
    22141 acgctttacc atcatgtcct aatcgatttg ttcatatctt atttcaatcc attataaata
    22201 gtgagaaata tctatcctat cttctagaat gtcttccaaa cgtggaaact ctcgtaaaca
    22261 aagaggtttt agaggcctat ttaccatgga ctaaagttgt acaagaaaag tgcaaataag
    22321 aaatctccag attaggaact atccgtgagt tctctagtct ggagattttt caatagactt
    22381 cgttattgga cggttacaat tcataaagtg ctgtagagag ataacgttca ccgttatctg
    22441 gtgctagggc aaggactttt ttacctgtac ctaatttttt ggcaacctcg atggctccgt
    22501 agatagctgc agctgaggaa atccctacaa ggaagccttc ttttccacca atttcacgtc
    22561 cgagtgcaag agcgtcatct gatgttacac gaacgatacc atcataggct ttagtatcaa
    22621 gtgtatcagg aataaatcca gctgagatac cttgaatttt gtgaggacca ggtttttcac
    22681 cagatagaat agcagattca tctgcttcta ctgcaaaaac ttgaatgtta gaattttctg
    22741 atttgagtgc atgagaaaca ccagaaatcg ttccaccagt acctactcca gcaacaaagg
    22801 catctaatcc atctttaccg aaagcagcta gtatctcagc tcctgttgtt ctttcgtgta
    22861 cttctggatt agctggattg tcaaattgaa gaggaaggaa accatcacgt tcagcagcga
    22921 tttcttgagc cttagcaata gcacctttca ttccctcgct accaggagtt aggacgagtt
    22981 cagcaccata agcttggata attttacgtc gttctacact catagtttca ggcataacga
    23041 tgacgacttt atacccttta gcagcaccta cccatgaaag tccaataccg gtgtttccac
    23101 ttgttgcttc aacaatagta gaaccaagtt tcagaatacc atcttgttca gctttttcaa
    23161 tcatgctaag ggcaatacgg tcttttacag atgaaccagg attaaatgct tcaagcttta
    23221 tatagacgtc tgcagcacct tctggcacga tgttgttaag tttaacaatc ggtgtttgac
    23281 cgattaattc agtaatgttg ttataaatag acatatgaat acctctttgt ataagatatc
    23341 tttagtataa cgctatccat accatttgta aaatatagaa atcctatcga agcgatagga
    23401 tttctatata tcatagatca aagtcattaa ttttcaagtg attgcgttca gttaattcta
    23461 gtaaataggt gtgaaggaaa acgatatcag gtttcgtttg aattgcttca ttttctagta
    23521 tattttggta cgcatctttt tattttgctc gctaaagtag ttgtgagaat gtcaacgaaa
    23581 cgctgtatta ttcattgttt acactaagtt tacagaaact tcaacctctc gtaaaccttg
    23641 gtcagttaaa gtgacttttc cattaaaaaa ctccacaagt gcagctttaa tagtttcttt
    23701 ttcttcttta tcaacataaa tcatcgtatc gacttgatct gtaaagtttg tatccagctc
    23761 catgagatca tgttctttaa ggaagttact gtactcttgg tactgagcat aagacatttg
    23821 aatagcaatg ccagcctgtt cttttatttc aataatacca atttctttga cagctaaggc
    23881 gacactgccg gcgtaagcac gaattagtcc tccagcgcct agtttaatac caccaaagta
    23941 gcgtgtcacg accacacaga cattggtgag attgtgattt tctagtaccc caagcatggg
    24001 aacaccagca gtaccactag gctcaccatc atcacttgta cgtttaattt cactacgttc
    24061 tccaataata aaggcagagc agttatgtgt cgctttgtag tgttcttttt tgatggcagt
    24121 aatgaagtca cgagcctctt cttcgctata aacacgcttg gcatggcaga taaagcgaga
    24181 ttttttgatt tcttcttgga cttggccgtc ctctttaatt gtcctaaatt ccatgattta
    24241 attgtactaa aaaataatct aaagtgctag tttttacgaa taaagaagta tgaaagtaaa
    24301 tttagattat ctcggtcgtt tatttactga gaatgaatta acagaagaag aacgtcagtt
    24361 ggcggagaaa cttccagcaa tgagaaagga gaaggggaaa cttttctgtc aacgttgtaa
    24421 tagtactatt ctagaagaat ggtatttgcc catcggtgct tactattgtc gagagtgctt
    24481 gctgatgaag cgagtcagaa gtgatcaaac tttatactat tttccgcagg aggattttcc
    24541 gaagcaagat gttctcaaat ggcgcggcca attaactcct tttcaagaga aggtgtcaga
    24601 gggactgctt caagcagtag acaagcaaaa gccaacctta gttcatgcgg taacaggagc
    24661 tggaaagaca gaaatgattt atcaagtagt ggctaaagtg atcaatgcgg gtggtgcagt
    24721 gtgtttggct agtcctcgca tagatgtttg tttggagctg tacaagcgcc tgcaacagga
    24781 tttttcttgc ggtatagctt tgctacatgg agaatcggaa ccttattttc gaacaccact
    24841 agttgttgca acaacccatc agttattgaa gttttatcaa gcttttgatt tgctgatagt
    24901 ggatgaagta gatgcttttc cttatgttga taatcccacg ctttaccacg ctgtcaagaa
    24961 tagtgtaaag gagaatggat tgagaatctt tttaacagcg acttcgacca atgagttaga
    25021 taaaaaggtc cgtttaggag aactaaaaag actgagttta ccgagacggt ttcatggaaa
    25081 tccgttgatt attccaaaac caatttggtt atcggatttt aatcgctact tagacaagaa
    25141 tcgtttgtca ccaaagttaa agtcctatat tgagaagcag agaaagacag cttatccgtt
    25201 actcattttt gcttcagaaa ttaagaaagg ggagcagtta gaagaaatct tacaggagca
    25261 atttccaaat gagaaaattg gctttgtatc ttctgtaaca gaggatcgat tagagcaagt
    25321 acaagctttt cgagatggag aactgacaat acttatcagt acgacaatct tggagcgtgg
    25381 agttaccttc ccttgtgtgg atgttttcgt aatagaggcc aatcatcgtt tgtttaccaa
    25441 gtctagtttg attcagattg gtggacgagt tggacgaagc atggatagac cgacaggaga
    25501 tttgcttttc ttccatgatg ggttaaatgc ttcaatcaag aaggcgatta aggaaattca
    25561 gatgatgaat aaggaggctg gtctatgaag tgcttgttat gtgggcagac tatgaagact
    25621 gttttaactt ttagtagtct cttacttctg aggaatgatg actcttgtct ttgttcagac
    25681 tgtgattcta cttttgaaag aattggggaa gagaactgtc caaattgtat gaaaacagag
    25741 ttgtcaacaa agtgtcaagc ttgtcaattt tggtgtaaag aaggagttga agtcagtcat
    25801 agagcgattt ttacttacaa tcaagctatg aaggattttt tcagtcggta taagtttgat
    25861 ggagacttcc tgttaagaaa agttttcgct tcatttttaa gtgaggagtt gaaaaagtac
    25921 aaagagtatc aatttgttgt aattccccta agtcctgata gatatgctaa cagaggattt
    25981 aatcaggttg agggcttggt agaggcagca ggctttgagt atctagattt attagagaaa
    26041 agagaagaga gagccagttc ttctaaaaat cgttcagagc gcttggggac agaacttcct
    26101 ttctttatta aaagtggagt cactattcct aaaaaaatcc tacttataga tgatatctat
    26161 actacaggag caactataaa tcgtgttaag aaactgttgg aagaagctgg tgctaaggat
    26221 gtaaaaacat tttcccttgt aagatgagga aaaaatttgc aaaaatagaa tgaaagcgtt
    26281 ataataaaat cataaaaaca aaaatgttta gaaagaaggt actcatatga ttaaatatag
    26341 tatccgtggt gaaaacctag aagtaacaga agcaattcgt gattatgtag tttctaaact
    26401 cgaaaagatc gaaaagtact tccaaccaga acaagagttg gatgcccgaa ttaacttaaa
    26461 agtttatcgt gaaaaaacgg ctaaagtgga agtaacgatt ccgcttggat ctattactct
    26521 ccgcgcagaa gatgtatctc aagatatgta tggttcaatt gaccttgtaa ctgataaaat
    26581 tgaacgtcag attcgtaaaa ataaaacaaa aatcgagcgt aaaaataaaa ataaggtagc
    26641 aactggtcaa ttatttacag atgctttggt ggaagattca aatattgtcc agtctaaagt
    26701 tgttcgttca aaacaaattg atttaaaacc aatggatttg gaagaagcaa ttctacaaat
    26761 ggatttattg gggcatgatt tctttatcta tgtggatgtt gaagatcaga caaccaatgt
    26821 gatttatcgt cgtgaggatg gcgaaattgg tttgttagag gttaaagaat cttaatttca
    26881 atatgtgtaa aggtaggttt actgaattgt aaactacctt tttcttataa ttgatagaat
    26941 tactgattac acttttaaaa agtcgctttt tgaggggtat tatggtataa tgggtgccaa
    27001 gaggttttga atgaaaaaat tttatgtaag tccaattttt cctattctag taggattgat
    27061 tgcgtttgga gtcttatcca ctttcattat ttttgttaat aataatctgt tgacggtttt
    27121 aattttgttt ctttttgtag gaggctatgt ttttttattt aagaaactga gagtgcatta
    27181 tacaaggagt gatgtagaac agatacagta tgtaaaccac caagcggaag aaagtttgac
    27241 agctctattg gaacagatgc ctgtaggtgt tatgaaattg aatttatctt ctggagaggt
    27301 tgagtggttt aatccctatg ctgaattgat tttgaccaag gaagatggtg attttgattt
    27361 agaagctgtt caaacgatta tcaaggcttc agtaggaaat ccgtctactt atgccaagct
    27421 tggtgagaag cgttatgctg ttcatatgga tgcttcttcc ggtgttttgt attttgtaga
    27481 tgtatccagg gaacaagcca taacagatga attggtaaca agtcgaccag tgattgggat
    27541 tgtctctgtg gataattatg atgatttgga ggatgcaact tctgagtcag atattagtca
    27601 aatcaatagt tttgtagcta attttatatc agagttttca gaaaaataca tgatgttttc
    27661 tcgtcgggta agtatggatc gattttatct atttactgac tacacggtgc ttgagggctt
    27721 gatgaatgat aaattttctg ttattgatgc tttcagagaa gagtcgaaac agagacagtt
    27781 gcccttgacc ttaagtatgg gattttctta tggcgatgga aatcatgatg agatagggaa
    27841 agttgctttg ctcaatttga acttggctga agtacgtggt ggcgaccagg tggttgttaa
    27901 ggaaaacgac gaaacgaaaa atccagttta ttttggtggt gggtctgctg cttcaatcaa
    27961 gcgtacacgg actcgtacgc gcgctatgat gacagctatt tcagataaga ttcggagtgt
    28021 agatcaggtt tttgtagtcg gtcacaaaaa tttagacatg gatgctttgg gctctgctgt
    28081 aggtatgcag ttgttcgcca gcaatgtgat tgaaaatagc tatgctcttt atgatgaaga
    28141 acaaatgtct ccagatattg aacgagctgt ttcattcata gaaaaagaag gagttacgaa
    28201 gttgttgtct gttaaggatg cattggggat ggtgaccaat cgttctttgt tgattcttgt
    28261 agaccattca aagacagcct taacattatc aaaagaattt tatgatttat ttacccaaac
    28321 cattgttatt gaccaccata gaagggatca ggattttcca gataatacgg tcattactta
    28381 tatcgaaagt ggtgcaagta gtgccagtga gttggtaacg gaattgattc agttccagaa
    28441 ttctaagaaa aatcgtttga gtcgtatgca agcaagtgtc ttgatggctg gtatgatgtt
    28501 ggatactaaa aatttcacct cgcgagtaac tagtcggaca tttgatgttg ctagctatct
    28561 cagaacgcgc ggaagtgata gtattgctat ccaggaaatc gctgcgacag attttgaaga
    28621 atatcgtgag gtcaatgaac ttattttaca ggggcgtaaa ttaggttcag atgtactaat
    28681 agcagaggct aaggacacga aatgctatga tacagttgtt attagtaagg cagcagatgc
    28741 catgttagcc atgtcaggta ttgaagcgag ttttgttctt gcgaagaata cacaaggatt
    28801 tatctctatc tcagctcgaa gtcgtagtaa actgaatgta caacggatta tggaagagtt
    28861 aggcggtgga ggccacttta atttggcagc agctcaaatt aaagatgtaa ccttgtcaga
    28921 agcaggtgaa aaactgacag aaattgtatt aaatgaaata aaggaaaagg agaaagaaga
    28981 atgaaagtaa tctttttagc agatgttaaa ggaaaaggta aaaaaggcga aattaaggaa
    29041 gtaccaacag ggtatgcgca aaactttctt atcaaaaaga atctagccaa agaagcgact
    29101 gctcaagctg taggtgaact tcgtggtaaa caaaaatcgg aagaaaaagc tcacgctgag
    29161 atgattgcag aaggaaaagc aattaaagca caacttgaag cagaagaaac tgttgtagaa
    29221 tttgttgaaa aagttggtcc agatggtcgt acctttggct ctattaccaa taagaagatt
    29281 gcagaagaat tgcaaaaaca atttggaatt aagattgata aacgtcatat tcaagtacaa
    29341 gctccgattc gagcggttgg tttgattgat gtgccagtga aaatctatca agatatcaca
    29401 agtgtaatca atcttcgtgt gaaagaagga taagtttaca ccttcttgac aagattgtaa
    29461 aaggaaggga agtctgatgg cagaagtaga agagttacga gtacaacctc aagatatctt
    29521 agctgagcaa tccgttttag gggctatctt tattgatgag agtaaacttg tttttgtgcg
    29581 agaatacatt gagtctcggg acttttttaa gtatgcccat cgtttgattt tccaagccat
    29641 ggtcgattta tccgatcgtg gtgatgccat agatgcaaca acggttcgta ctatccttga
    29701 taatcaaggt gatttacaga atattggtgg cttgtcttac ttggttgaga ttgttaattc
    29761 tgtgccaact tctgctaatg cggagtatta tgctaagatt gttgcagaaa aagcaatgct
    29821 acgtcgttta attgccaagt tgacagagtc tgtcaaccaa gcttacgaag cgtcacaacc
    29881 agctgatgaa attattgctc aggcagaaaa agggctgatt gatgtcagtg aaaatgcaaa
    29941 tcgaagcggg tttaagaaca ttcgagatgt gttgaatctc aactttggaa atctggaagc
    30001 tcgctcgcaa caaacgaccg atattacagg tattgcgaca ggttatcgtg atttggatca
    30061 tatgacaaca ggacttcatg aggaggagtt gattatctta gcagctcgtc cagcagttgg
    30121 taagacagca tttgccttga atatcgctca gaacattggg actaagttgg acaaaacggt
    30181 tgctattttt tcactcgaaa tgggtgcgga aagcttggta gatcgtatgt tagctgcaga
    30241 aggcttagtg gagtcacatt ctatccgtac agggcaattg acagatgagg agtggcaaaa
    30301 atatactatt gctcagggta atctagctaa cgccagtatc tatatcgatg atacgccagg
    30361 tattcggatt acagagattc gttctcgttc tcgtaaattg gctcaagaaa ctggaaatct
    30421 tggtttgatt ttgatagact atttgcaact tatcacggga actggtcgag aaaatcgtca
    30481 acaagaagtt tctgaaattt ctcgtcagtt gaaaatacta gccaaggaat tgaaggttcc
    30541 agtaatcgct ctgagtcagc tttctcgtgg tgtagaacaa cgtcaggaca agagaccggt
    30601 cttgtctgat attcgtgaat ctgggtctat tgagcaggac gctgatatcg tagcttttct
    30661 ctatcgcgat gactactatg aacgtggtgg tgaagaagag gagggtatcc caaataataa
    30721 ggtggaagtt attatcgaga aaaaccgtag tggagctcgt ggaacagtgg aattgatttt
    30781 ccaaaaagaa tacaataaat tttcaagtat ctcaaagagg gaggcataag atgtcagatg
    30841 catttacaga tgtagccaag atgaaaaaaa tcaaagaaga aatcaaggca catgagggac
    30901 aagtcgtaga aatgactttg gagaatggtc gtaagcgcca aaaaaataga ttgggtaagc
    30961 taattgaagt ttatccatct ctatttattg tggagtttgg ggatgtggaa ggagataaac
    31021 aagttaatgt ttacgttgaa tcctttactt actcagatat tcttacagaa aagaatttga
    31081 ttcattatct tgactaaagt gagaaatttt ctcacttttt cttttttctc cgaataattt
    31141 aggtgaaggc aatcatcgct ttatattatt tttcaaggag gaagaatgaa aattttaccg
    31201 tttatagcaa gaggaacaag ttattacttg aagatgtcag ttaaaaagct tgttcctttt
    31261 ttagtagtag gattgatgct agcagctggt gatagtgtct atgcctattc cagaggaaat
    31321 ggatcgattg cgcgtgggga tgattatcct gcttattata aaaatgggag ccaggagatt
    31381 gatcagtggc gcatgtattc tcgtcagtgt acttcttttg tagcctttcg tttgagtaat
    31441 gtcaatggtt ttgaaattcc ggcagcttat ggaaatgcga atgaatgggg acatcgtgct
    31501 cgtcgggaag gttatcgtgt agataataca ccgacgattg gttccattac ttggtctact
    31561 gcaggaactt atggtcatgt tgcctgggtg tcaaatgtaa tgggagatca gattgagatt
    31621 gaggaatata actatggtta tacagaatcc tataataaac gagttataaa agcaaacacg
    31681 atgacaggat ttattcattt taaagatttg gatggtggca gtgttgggaa tagtcaatcc
    31741 tcaacttcaa caggcggaac tcattatttt aagaccaagt ctgctattaa aactgaaccc
    31801 ctagttagtg caactgtgat tgattactat tatcctggag agaaggttca ttatgatcaa
    31861 attctcgaaa aagacggcta caagtggttg agttatactg cctataatgg aagctatcgt
    31921 tatgttcaat tggaggctgt gaataaaaat cctctaggta attctgttct ttcttcaaca
    31981 ggtggaactc attattttaa gaccaagtct gctatcaaaa ctgaacccct agttagcgga
    32041 actgtgattg attactatta tcctggggag aaggttcatt atgatcagat acttgaaaaa
    32101 gacggctaca agtggttgag ttatactgcc tataatggaa gtcgtcgcta tatacagcta
    32161 gagggagtga cttcttcaca aaattatcag aatcaatcag gaaatatctc tagctatgga
    32221 tccaataata gttcaactgt cggttggaag aaaataaatg gtagttggta tcatttcaaa
    32281 tcaaatggtt ctaaatcaac aggatggctg aaagacggtt ctagctggta ttatttgaaa
    32341 ttatctggtg aaatgcagac aggatggtta aaggagaatg gctcgtggta ttatctgggt
    32401 agttcagggg caatgaaaac aggctggtac caggtctctg gtaagtggta ttattcttac
    32461 tcttcaggcg ccttagctgt taatacgacg gtggatggct acagagtaaa cagtgatgga
    32521 gaacgagtat agaaaattgg agtaggagaa atttcctgct cttttctgta agcagtttcc
    32581 ttgacatttt tcttattttg cgctatcata tatacatata atatatggga gtctgtgtac
    32641 agtctgagag gaagtgttaa acttcgaccg cacctgatct gggtaatgcc agcggaggga
    32701 acgatactta gtctaatttt gcaccttttc catgtatggt aaaggttttt ctttttttta
    32761 aaaggaaaac gagaagagga ggttcttatg aaagcaagca ttgccttgca agttttaccc
    32821 ctagcacagg ggattgatcg gatagctgtt attgatcagg tcattgctta tctgcaaact
    32881 caagaagtga cgatggtagt gacaccattt gaaacggtct tggaagggga gtttgatgag
    32941 cttatgcgca ttctaaaaga agcgctggaa gtggcagggc aggaggcaga caatgtcttt
    33001 gccaatgtca aaataaatgt aggagagatt ttaagtattg atgagaaact tgaaaagtat
    33061 actgagacga cacattagtc tattgggctt tctcggagta ttgtcaatct ggcagttagc
    33121 aggttttctt aaacttctcc ccaagtttat cctgccgaca cctcttgaaa ttctccagcc
    33181 ctttgttcgt gacagagaat ttctctggca ccatagctgg gcgaccttga gagtggcttt
    33241 actggggctg attttgggag ttttgattgc ctgtcttatg gctgtgctca tggatagttt
    33301 gacttggctc aatgacctga tttaccctat gatggtggtc attcagacca ttccgaccat
    33361 tgccatagct cctatcctgg tcttgtggct gggttatggg attttgccca agattgtctt
    33421 gattatctta acaacaacct ttcccatcat cgttagtatt ttggacggtt ttaggcattg
    33481 tgacaaggat atgctgactt tgtttagtct gatgcgagca aacccttggc aaatcctgtg
    33541 gcattttaaa atcccggtta gcctgcctta cttttatgca ggtctgaggg tcagtgtctc
    33601 ctacgccttt atcacaactg tggtatctga gtggttggga ggttttgaag gtcttggtgt
    33661 ttatatgatt cagtctaaaa aactgtttca gtatgatacc atgtttgcca ttattattct
    33721 ggtgtcgatt atcagtcttt tgggtatgaa gctggtcgat atcagtgaaa aatatgtgat
    33781 taaatggaaa cgtacttaaa atagagcgtt tttgaaaaag aaaagaggaa atcaaaatga
    33841 agaaaacatg gaaagtgttt ttaacgcttg taacagctct tgtagctgtt gtgcttgtgg
    33901 cctgtggtca aggaactgct tctaaagaca acaaagaggc agaacttaag aaggttgact
    33961 ttatcctaga ctggacacca aataccaacc acacagggct ttatgttgcc aaggaaaaag
    34021 gttatttcaa agaagctgga gtggatgttg atttgaaatt gccaccagaa gaaagttctt
    34081 ctgacttggt tatcaacgga aaggcaccat ttgcagtgta tttccaagac tacatggcta
    34141 agaaattgga aaaaggagca ggaatcactg ccgttgcagc tattgttgaa cacaatacat
    34201 caggaatcat ctctcgtaaa tctgataatg taagcagtcc aaaagacttg gttggtaaga
    34261 aatatgggac atggaatgac ccaactgaac ttgctatgtt gaaaaccttg gtagaatctc
    34321 aaggtggaga ctttgagaag gttgaaaaag taccaaataa cgactcaaac tcaatcacac
    34381 cgattgccaa tggcgtcttt gatactgctt ggatttacta cggttgggat ggtatccttg
    34441 ctaaatctca aggtgtagat gctaacttca tgtacttgaa agactatgtc aaggagtttg
    34501 actactattc accagttatc atcgcaaaca acgactatct gaaagataac aaagaagaag
    34561 ctcgcaaagt catccaagcc atcaaaaaag gctaccaata tgccatggaa catccagaag
    34621 aagctgcaga tattctcatc aagaatgcac ctgaactcaa ggaaaaacgt gactttgtca
    34681 tcgaatctca aaaatacttg tcaaaagaat acgcaagcga caaggaaaaa tggggtcaat
    34741 ttgacgcagc tcgctggaat gctttctata aatgggataa agaaaatggt atccttaaag
    34801 aagacttgac agacaaaggc ttcaccaacg aatttgtgaa ataatgacag aaattagact
    34861 agagcatgtc agttatgcct atggtcagga gaggatttta gaggatatca acctacaggt
    34921 gacttcaggc gaagtggttt ccattctagg cccaagtggt gttggaaaga ccaccctctt
    34981 taatctaatc gctgggattt tagaagttca gtcagggaga attgtccttg atggtgaaga
    35041 aaatcccaag gggcgcgtga gttatatgtt gcaaaaggat ctgctcttgg agcacaagac
    35101 ggtgcttgga aatatcattc tgcccctctt gattcaaaag gtggataagg cagaagctat
    35161 ttcccgagcg gataaaattc ttgcgacctt ccagctgaca gctgtaagag acaagtatcc
    35221 tcatgaactt agcggtggga tgcgccagcg tgtagcctta ctccggacct acctttttgg
    35281 gcacaagctc tttctcttag atgaggcctt tagcgccttg gatgagatga caaagatgga
    35341 actccacgct tggtatcttg agattcacaa acagttgcag ctaacaaccc tgatcatcac
    35401 gcatagtatt gaggaggccc tcaatctcag cgaccgtatc tatatcttga aaaatcgccc
    35461 tgggcagatt gtttcagaaa ttaaactaga ttggtctgaa gatgaggaca aggaagtcca
    35521 aaagattgcc tacaaacgtc aaatcttggc agaattaggc ttagataagt agaaaaatag
    35581 ggagttggtg aagattatcc tttaccagcg ccctttttct tttaaaaatg agaaaatttc
    35641 ggtataatag tcaaacaagg tcaaggttta aagagagagg tgggtttgtt atgagattta
    35701 aaaatacatc ggatcatatt gaggcctaca tcaaggcgat tttagatcaa tctggtatcg
    35761 tggagttgca acggagtcag ttggcagata cctttcaggt tgttcctagt cagattaact
    35821 acgtgatcaa gacacgcttt acggaaagta gaggctactt ggttgaaagt aagcgtggtg
    35881 gcggaggcta cattcgtata ggacggattg agttttctag tcatcatgaa atgctccggg
    35941 agctgcttta ctcgattggt gagcgagtca gtcaagaaat ttatgaggat attctccagc
    36001 ttttggttga gcaggaattg atgaccaagc aggagatgaa tttgctagaa tcagtagctt
    36061 tggatcgcgt tttaggagaa gaagctccag ttgttcgagc aaacatgcta cgtcaggtca
    36121 tacaagaggt agatagaaaa gggaagtaag atgaactatt caaaagcatt gaatgaatgt
    36181 atcgaaagtg cctacatggt tgctggacat tttggagctc gttatctaga gtcgtggcac
    36241 ttgttgattg ccatgtctaa tcacagttat agtgtagcag gggcaacttt aaatgattat
    36301 ccgtatgaga tggaccgttt agaagaggtg gctttggaac tgactgaaac ggactatagc
    36361 caggatgaaa cctttatgga attgccgttc tcccgtcgtt tgcaggttct ttttgatgaa
    36421 gcagagtatg tagcgtcagt ggtccatgct aaggtactag ggacagagca cgtcctctat
    36481 gcgattttgc atgatggcaa tgccttggcg actcgtatct tggagagggc tggtttttct
    36541 tatgaagaca agaaagatca ggtcaagatt gctgctcttc gtcgaaattt agaagaacgg
    36601 gcaggctgga ctcgtgaaga tctcaaggct ttacgccaac gccatcgtac tgtggctgac
    36661 aaacaaaatt ctatggccaa tatgatgggc atgccgcaga ctcctagtgg tggtctcgag
    36721 gactatacgc atgatttgac agagcaagcg cgttctggca agttagaacc agtcatcggt
    36781 cgggacaagg aaatctcacg tatgattcaa atcttgagcc gtaagactaa gaacaaccct
    36841 gtcttggttg gggatgctgg tgtcgggaaa acagctctgg tgcttggtct tgctcagcgt
    36901 attgccagtg gtgatgtgcc tgcggaaatg gctaagatgc gcgtgttaga acttgatttg
    36961 atgaatgtcg ttgcagggac acgcttccgt ggtgactttg aagaacgcat gaataatatc
    37021 atcaaggata ttgaagaaga tggccaagtc atcctcttta tcgatgaact ccacaccatc
    37081 atgggttctg gtagcgggat tgattcgact ctggatgcgg ccaatatctt gaaaccagcc
    37141 ttggcgcgtg gagctttgag aacggttggt gccaccactc aggaagaata tcaaaaacat
    37201 atcgaaaaag atgcggctct ttctcgtcgt ttcgctaaag tgacgattga agaaccaagt
    37261 gtggcagata gtatgactat tttacaaggt ttgaaggcga cttatgagaa acatcaccgt
    37321 gtacaaatca cagatgaagc ggttgaaaca gcggttaaga tggctcatcg ttatttaacc
    37381 agtcgtcact tgccagactc tgctatcgac ctcttggacg aagcagcagc aacagtgcaa
    37441 aataaggtaa agtatgtaaa agcagacgat tcagatttga gtccagctga taaggccctg
    37501 atggatggca agtggaaaca ggcagcccag ctaatcgcaa aagaagagga agtacctgtc
    37561 tacaaagact tggtgacaga gtctgatatt ttgaccacct tgagtcgctt gtcaggaatc
    37621 ccagttcaaa aactgactca aacggatgct aagaagtatc taaatcttga agcagaactc
    37681 cataaacgtg tcatcggtca agatcaagct gtttcaagca ttagtcgtgc gattcgccgt
    37741 aatcagtcag gaattcgcag tcacaagcgt ccgatcggtt cctttatgtt cctaggaccc
    37801 acaggtgtcg gtaagaccga gttggccaag gctttggcag aagttctctt tgatgacgaa
    37861 tcagccctta tccgctttga tatgagtgag tatatggaga aattcgcagc cagccgtcta
    37921 aatggagctc ctccaggcta tgtgggttac gaagaaggtg gagagttgac agagaaggtt
    37981 cgcaataaac cctattccgt tctcctcttt gatgaggtag agaaggccca cccagatatt
    38041 tttaatgttc tcttgcaggt tctggatgac ggtgttttga cagatagcaa gggacgcaag
    38101 gtcgattttt caaataccat tatcattatg acatcgaacc taggtgcgac tgcccttcgt
    38161 gatgataaga ctgttggttt tggggctaag gatattcgtt ttgaccagga aaatatggaa
    38221 aaacgcatgt ttgaagaact gaaaaaagct tatagaccgg aattcatcaa ccgtattgat
    38281 gagaaggtgg tcttccatag cctatctagt gaccatatgc aggaagtggt gaagattatg
    38341 gtcaagcctt tagtggcaag tttggctgaa aaaggcattg acttgaaatt acaagcttca
    38401 gctctgaaat tgttagcaaa tcaaggatat gacccagaga tgggagctcg cccacttcgc
    38461 agaaccctgc aaacagaagt ggaggacaag ttggcagaac ttcttcttaa gggagattta
    38521 gtggcaggca gcacacttaa gattggtgtc aaagcaggcc agttaaaatt tgatattgca
    38581 taaaagaata aaagtatcag catctgacca taagtcacag tggagtgaaa ctcaatgaaa
    38641 atcaaagagc aaactaggca gctagccgca ggttgctcaa aacactggtt tgaggttgca
    38701 gatagagctg acgtggtttg aagagatttt cgaagagtat gaaactaaaa cctatagctt
    38761 ctaaacgatc cgtggttttc accattcaac acaaaattca tatgtttatt accctccgtc
    38821 gtatttgtct tagagcgtgt gtagtagaaa aagagcagtc ttatctgaaa tttttattct
    38881 ttcaaaagag acctgtttct tttttgcatg tcaaatccgt tctagctggt atttgaaaaa
    38941 tcaaactaat attcaatgaa aatcaaagaa caaactaggc agctagccac aggttgctca
    39001 aaacactgtt ttgaggttgt agatagagct gacgtagttt gaagagattt tcgaagagta
    39061 taagctgcaa gatgaatgat tttcttgtat tgacgttgtt gttgacaaaa agtagcggat
    39121 aaatgaaatc cattccatta tcatagatga taggctggta ggaaattttc aaatagcata
    39181 caggaaatag atgtatggag ttctggtagt agaaagggag agagatgaac attttagttg
    39241 cagatgacga ggaaatgatt agagaaggaa ttgcagcatt tctgacagaa gagggttatc
    39301 atgtcattat ggctaaggat ggacaagagg tcttggaaaa atttcaagat ctccctatcc
    39361 atctcatggt attggattta atgatgccta ggaagagtgg ttttgaagtg ttaaaagaaa
    39421 tcaatcaaaa gcacgatatt cctgtcatcg tcttgagtgc tctgggagat gaaactactc
    39481 agtcacaggt atttgatctc tatgctgatg atcatgtgac aaaacctttt tctttggtac
    39541 tgcttgtcaa gcgtattaag gcgcttatca gacgttacta cgtcatagag gatatttggc
    39601 gatatcagga tgtaacagtg gattttacct cttacaaagc acattataaa aatgaagaaa
    39661 ttgatctcaa accaaaggaa ttactggtac taaagtgttt gattcagcat aaaaatcaag
    39721 ttttaagtag agagcagata ttggaagaaa tttcaaaaga tgtagctgat ttaccttgtg
    39781 atagggtcgt tgatgtctat attcgtactc ttcgcaaaaa attagcttta gattgtatcg
    39841 tgactgtgaa aaatgttggg tataagatta gcttatgata aaaaatccta aattattaac
    39901 caagtctttt ttaagaagtt ttgcaattct aggtggtgtt ggtctagtca ttcatatagc
    39961 tatttatttg acctttcctt tttattatat tcaactggag ggggaaaagt ttaatgagag
    40021 cgcaagagtg tttacggagt atttaaagac taagacatct gatgaaattc caagcttact
    40081 ccagtcttat tcaaagtcct tgaccatatc tgctcacctt aaaagagata ttgtagataa
    40141 gcgactccct cttgtgcatg acttggatat taaagatgga aagctatcaa attatatcgt
    40201 gatgttagat atgtctgtta gtacagcaga tggtaaacag gtaacagtgc aatttgttca
    40261 cggggtggat gtctacaaag aagcaaagaa tattttgttt ttgtatcttc catatacatt
    40321 tttggttaca attgcttttt cctttgtttt ttcttatttt tatactaaac gcttgctcaa
    40381 tcctcttttt tacatttcag aagtgactag taaaatgcaa gatttggatg acaatattcg
    40441 ttttgatgaa agtaggaaag atgaagttgg tgaagttgga gaagttggaa aacagattaa
    40501 tggtatgtat gagcacttgt tgaaggttat tcatgagttg gaaagtcgta atgagcaaat
    40561 tgtaaaattg caaaatcaaa aggtttcctt tgtccgtgga gcatcacatg agttgaaaac
    40621 ccctttagcc agtcttagaa ttatcctaga gaatatgcag cataatattg gagattacaa
    40681 agatcatcca aaatatattg caaagagtat aaataagatt gaccagatga gccacttatt
    40741 ggaagaagta ctggagtctt ctaaattcca agagtggaca gagtgtcgtg agaccttgac
    40801 tgttaagcca gttttagtag atattttatc acgttatcaa gaattagctc attcaatagg
    40861 tgttacaatt gaaaatcaat tgacagatgc taccagggtc gtcatgagtc ttagggcatt
    40921 ggataaggtt ttgacaaacc tgattagtaa tgcaattaaa tattcagata aaaatgggcg
    40981 cgtaatcata tccgagcaag atggctatct ctctatcaaa aatacatgtg cgcctctaag
    41041 tgaccaagaa ctagaacatt tatttgatat attctatcat tctcaaatcg tgacagataa
    41101 ggatgaaagt tccggtttgg gtctttacat tgtgaataat attttagaaa gctatcaaat
    41161 ggactatagt tttctccctt atgaacacgg tatggaattt aagattagct tgtagacaga
    41221 ttagtttttt attaaagttc atatagggtt aacataagtg tgttattctt tgtgtagata
    41281 aaagaaagga tactaatatg gtattagcga ttattttagt aacattcttt attcgattga
    41341 tttttttaaa gcgttcgata gagaatgaga aacgaatcct tagcaatggc gggaaagaat
    41401 ttggagttga gaatacaaaa cgattaacta tggctcatat tgttttttat ctctcttgct
    41461 tggttgaggc aatggtgcac aagacaattt ttgatggcat gggcatggtt ggtttagtct
    41521 tgcttatttt ttctatgctg atgttaatgt tggtgattca cttgttggga gatatttgga
    41581 cagtgaagct tatgcttgtc aataatcaca aatatgtaga tcatatcttg tttaggacag
    41641 taaaacatcc taattacttt ttaaatattc ttcctgagtt gattggcttg accttgttga
    41701 gtcatgctta tgtgactttt gttttagttt ttccagttta tgcagttatt ttgtatcgac
    41761 gaatagctga agaggaaaag ctattacatg aagttataat cccaaatgga agcataaaga
    41821 gataaataca aaattcgatt tatatacagt tcatattgaa gtgatatagt aaggttaaag
    41881 aaaaaatata gaaggaaata aacatgtttg catcaaaaag cgaaagaaaa gtacattatt
    41941 caattcgtaa atttagtatt ggagtagcta gtgtagtagt tgctagcttg ttcttaggag
    42001 gagtagttca tgcagaaggg gttagaagtg gggatacccc caaggttaca tctagtgggg
    42061 atgaagtcga gtcgcatcta aaaaaaatat tgagtgagat ccaaacacaa ttagatagaa
    42121 aacgacatgc caaaactgta gcgctaatta acaagttgca agacattaag agaacgtatt
    42181 cgtataaatt aaatgtttta gaagagaagc cgaaagctga gttgacgtca aaaacaaaag
    42241 aagagttaac cgcagctttt gagcaattta aaaaagatac attaccaaca gaaccaggaa
    42301 aaaaggtagc agaagctgag aagaaggttg cagaagctga gaaaaaagcc gaggatcaaa
    42361 aagaagaaga tcgtcgtaac tacccaacca atacttacaa aacgcttgaa cttgaaattg
    42421 ctgagttcga tgtgaaagtt aaagaagcgg agcttgaact attaaaagag aaagctaaga
    42481 aacctttaaa cgagggcaca attaagcaag caaaagagaa agttgagagt aaaaaagctg
    42541 aggctacaag gttagaaaac atcaagacag atcgtaaaaa agcagaagaa gaagctaaac
    42601 gaaaagcagc agaagaagat aaagttaaag aaaaaccagc tgaacaacca caaccagcgc
    42661 cggctcctca accagaaaaa ccagctccaa aaccagaaaa accagctcca gctccaaaac
    42721 cagagaatcc agctccaaaa ccagaaaaac cagctccagc tccaaaacca gagaatccag
    42781 ctgaacaacc aaaagcagaa aaaccagctg atcaacaagc tgaagaagac tatgctcgta
    42841 gatcagaaga agaatataat cgcttgactc aacagcaacc gccaaaaact gaaaaaccag
    42901 cacaaccatc tactccaaaa acaggctgga aacaagaaaa cggtatgtgg tacttctaca
    42961 atactgatgg ttcaatggcg acaggatggc tccaaaacaa tggctcatgg tactacctca
    43021 acagcaatgg cgctatggcg acaggatggc tccaaaacaa tggttcatgg tactatctaa
    43081 acgctaatgg ttcaatggca acaggatggc tccaaaacaa tgg
//
LOCUS       DAVBEO010000011        42638 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 009
            SAMEA1678075-rid20185393.denovo.011, whole genome shotgun sequence.
ACCESSION   DAVBEO010000011 DAVBEO010000000
VERSION     DAVBEO010000011.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678075
            Sequence Read Archive: ERR226392
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 42638)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 42638)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980207.1
            Genome Coverage       :: 150x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:50:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 72 of 147
            Pseudo Genes (incomplete)         :: 72 of 147
            Pseudo Genes (internal stop)      :: 42 of 147
            Pseudo Genes (multiple problems)  :: 32 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..42638
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678075-rid20185393.denovo.011"
                     /strain="KS 009"
                     /db_xref="taxon:1313"
     gene            1..404
                     /locus_tag="VQ543_000644"
                     /pseudo
     CDS             1..404
                     /locus_tag="VQ543_000644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611513.1"
                     /note="internal stop; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            complement(449..1090)
                     /gene="plsY"
                     /locus_tag="VQ543_000645"
     CDS             complement(449..1090)
                     /gene="plsY"
                     /locus_tag="VQ543_000645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000628793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate 1-O-acyltransferase PlsY"
                     /protein_id="HET2611414.1"
                     /translation="MITIVLLILAYLLGSIPSGLWIGQVFFQINLREHGSGNTGTTNT
                     FRILGKKAGMATFVIDFFKGTLATLLPIIFHLQGVSPLIFGLLAVIGHTFPIFAGFKG
                     GKAVATSAGVIFGFAPIFCLYLAIIFFGALYLGSMISLSSVTASIAAVIGVLLFPLFG
                     FILSNYDSLFIAIILALASLIIIRHKDNIARIKNKTENLVPWGLNLTHQDPKK"
     gene            1226..3169
                     /gene="parE"
                     /locus_tag="VQ543_000646"
     CDS             1226..3169
                     /gene="parE"
                     /locus_tag="VQ543_000646"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit B"
                     /protein_id="HET2611415.1"
                     /translation="MSKKEININNYNDDAIQVLEGLDAVRKRPGMYIGSTDGAGLHHL
                     VWEIVDNAVDEALSGFGDRIDVTINKDGSLTVQDHGRGMPTGMHAMGIPTVEVIFTIL
                     HAGGKFGQGGYKTSGGLHGVGSSVVNALSSWLEVEITRDGAVYKQRFENGGKPVTTLK
                     KIGTAPKSKTGTKVTFMPDATIFSTTDFKYNTISERLNESAFLLKNVTLSLTDKRTDE
                     AIEFHYENGVQDFVSYLNEDKEILTPVLYFEGEDNGFQVEVALQYNDGFSDNILSFVN
                     NVRTKDGGTHETGLKSAITKVMNDYARKTGLLKEKDKNLEGSDYREGLAAVLSILVPE
                     EHLQFEGQTKDKLGSPLARPVVDGIVADKLTFFLMENGELASNLIRKAIKARDAREAA
                     RKARDESRNGKKNKKDKGLLSGKLTPAQSKNPAKNELYLVEGDSAGGSAKQGRDRKFQ
                     AILPLRGKVINTAKAKMADILKNEEINTMIYTIGAGVGADFSIEDANYDKIIIMTDAD
                     TDGAHIQTLLLTFFYRYMRPLVEAGHVYIALPPLYKMSKGKGKKEEVAYAWTDGELEE
                     LRKQFGKGATLQRYKGLGEMNADQLWETTMNPETRTLIRVTIEDLARAERRVNVLMGD
                     KVEPRRKWIEDNVKFTLEEATVF"
     gene            3589..6060
                     /gene="parC"
                     /locus_tag="VQ543_000647"
     CDS             3589..6060
                     /gene="parC"
                     /locus_tag="VQ543_000647"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit A"
                     /protein_id="HET2611416.1"
                     /translation="MSNIQNMSLEDIMGERFGRYSKYIIQDRALPDIRDGLKPVQRRI
                     LYSMNKDSNTFDKSYRKSAKSVGNIMGNFHPHGDSSIYDAMVRMSQNWKNREILVEMH
                     GNNGSMDGDPPAAMRYTEARLSEIAGYLLQDIEKNTVPFAWNFDDTEKEPTVLPAAFP
                     NLLVNGSTGISAGYATDIPPHNLAEVIDAAVYMIDHPTAKIDKLMEFLPGPDFPTGAI
                     IQGRDEIKKAYETGKGRVVVRSKTEIEKLKGGKEQIVITEIPYEINKANLVKKIDDVR
                     VNNKVAGIAEVRDESDRDGLRIAIELKKDANTELVLNYLFKYTDLQINYNFNMVAIDN
                     FTPRQVGIVPILSSYIAHRREVILARSRFDKEKAEKRLHIVEGLIRVISILDEVIALI
                     RASENKADAKENLKVSYDFTEEQAEAIVTLQLYRLTNTDVVVLQEEEAELREKIAMLA
                     AIIGDERTMYNLMKKELREVKKKFATPRLSSLEDTAKAIEIDTASLIAEEDTYVSVTK
                     AGYIKRTSPRSFAASTLEEIGKRDDDRLIFVQSAKTTQHLLMFTSLGNVIYRPIHELA
                     DIRWKDIGEHLSQTITNFETNEEILYVEVLDQFDDATTYFAVTRLGQIKRVERKEFTP
                     WRTYRSKSVKYAKLKDDTDQIVAVAPIKLDDVVLVSQNGYALRFNIEEVPVVGAKAAG
                     VKAMNLKEDDVLQSGFICNTSSFYLLTQRGSLKRVSIEEILATSRAKRGLQVLRELKN
                     KPHRVFLAGAVAEQGFVGDFFSTEVDVNDQTLLVQSNKGTIYESRLQDLNLSERTSNG
                     SFISDTISDEEVFDAYLQEVVTEDK"
     gene            6192..7214
                     /locus_tag="VQ543_000648"
     CDS             6192..7214
                     /locus_tag="VQ543_000648"
                     /EC_number="2.6.1.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid aminotransferase"
                     /protein_id="HET2611417.1"
                     /translation="MTVTIDWENLGFSYMKLPYRYLAHFKNGQWDQGELTEDATLHIS
                     ESSPSLHYGQQAFEGLKAYRTKDGSVQLFRPDENAKRLQRTCDRLLMPQVPTDMFVEA
                     CKAVVRANEEYVPPYGTGGTLYLRPLLIGVGDIIGVKPAEEYIFTIFAMPVGNYFKGG
                     LVPTNFLIQDEYDRAAPNGTGAAKVGGNYAASLLPGKMAKSRHFSDVIYLDPSTHTKI
                     EEVGSANFFGITADNEFVTPLSPSILPSITKYSLLYLAEHRLGLTPIEGDVPIDNLDR
                     FVEAGACGTAAVISPIGGIQHGDDFHVFYSETEVGPVTRKLYNELTGIQFGDIEAPEG
                     WIVKVD"
     gene            7270..7974
                     /locus_tag="VQ543_000649"
     CDS             7270..7974
                     /locus_tag="VQ543_000649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HET2611418.1"
                     /translation="MVLSTSAILVACGKTDKEADAPTTFSYVYAVDPASLGYSIATRT
                     SRTDVIGNVIDGLMENDKYGNVAPSQKDYDLNSTGWAPSYQDPASYLNIMDPKSGSDM
                     KHLGITKGKDKDVVAKPGLDKYKKLLEDAVSETTDLEKRYEKYAKAQAWSTDSSLLMP
                     TASSGGFPVVSNVVPFSKPYSQVGIKGEPYIFKGMKLQKDIVTTKEYNEVFKKWQKEK
                     LESNSKYQKELEKYIK"
     gene            8039..8728
                     /locus_tag="VQ543_000650"
     CDS             8039..8728
                     /locus_tag="VQ543_000650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000454813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF969 domain-containing protein"
                     /protein_id="HET2611419.1"
                     /translation="MEWIRLIGIAIIVVGFILKFDTIATVVLAGLVTALVSGVSLVEF
                     LEILGKEFSNQRVLTIFMVTLPLVGLSETFGLKQRSIDLIRKIKGLTVGNFYTVYFFI
                     RELAGFFSIRLGGHPQFVRPLVQPMGEAAAESQLGRKLTEVEDETIKARAAANENFGN
                     FFAQNTFVGAGGVLLIGGTLDQLGYESNYAGIASTSIIVAVITLIVVGIYNYLFDKKL
                     ISKKTRGGEQK"
     gene            8725..9648
                     /locus_tag="VQ543_000651"
     CDS             8725..9648
                     /locus_tag="VQ543_000651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000137271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF979 domain-containing protein"
                     /protein_id="HET2611420.1"
                     /translation="MTELAKQLLELTYIVIGCQFLHTAYCSYKDKTNPVRLGTSAFWT
                     LLSITFIGGSYMPNMSIGIIVILLSLLTLFKQVRIGTLPSLDEMKANIESNRLKNKIF
                     IPVMLMAILALVLAQMIPEFSKISISLAALFATISVLVITNSHPKSLLSENNRMTQQV
                     STSGIVPQLLGALGAIFTVAGVGDVISHLISGIVPSDSRFIGVLAYVLGMVLFTMIMG
                     NAFAAFTVITAGVGVPFVFALGANPIVAGALAMTAGYCGTLLTPMAANFNALPAALMD
                     MKDQNGVIKAQAGVALVMIVIHIFLMYFLAF"
     gene            9663..10307
                     /gene="pcp"
                     /locus_tag="VQ543_000652"
     CDS             9663..10307
                     /gene="pcp"
                     /locus_tag="VQ543_000652"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HET2611421.1"
                     /translation="MKILVTGFNPFGGEKINPALEAVKLLPSEINGAEVRWVEIPTVF
                     YKSSEVLEAEILRYQPDAVLCIGQAGGRTGLTPERVAINQDDARIPDNEGNQPIDTPI
                     RIDGASAYFSSLPIKAMVQAIKKQGLPAVVSNSAGTFVCNHLMYQALYLVDKKFPNMR
                     AGFMHIPYMMEQVVNKPNTAGMSLCDIVRGIEVAIEAIVDYKDKDLQLVGGETH"
     gene            10475..10705
                     /locus_tag="VQ543_000653"
     CDS             10475..10705
                     /locus_tag="VQ543_000653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000037109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2969 domain-containing protein"
                     /protein_id="HET2611422.1"
                     /translation="MSKKDKKIEIQVADAKVNVGKDSFEGYTLTIGKKVIGEIAELDG
                     QFAIIKNGNVDSFYKKLEKAVEILIENYNLAK"
     gene            10755..10835
                     /locus_tag="VQ543_000654"
     tRNA            10755..10835
                     /locus_tag="VQ543_000654"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:10789..10791,aa:Tyr,seq:gta)
     gene            10845..10916
                     /locus_tag="VQ543_000655"
     tRNA            10845..10916
                     /locus_tag="VQ543_000655"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:10877..10879,aa:Gln,seq:ttg)
     gene            11078..12280
                     /gene="rpsA"
                     /locus_tag="VQ543_000656"
     CDS             11078..12280
                     /gene="rpsA"
                     /locus_tag="VQ543_000656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S1"
                     /protein_id="HET2611423.1"
                     /translation="MNEFEDLLNSVSQVETGDVVSAEVLTVDATQANVAISGTGVEGV
                     LTLRELTNDRDADINDFVKVGEVLDVLVLRQVVGKDTDTVTYLVSKKRLEARKAWDKL
                     VGREEEVVTVKGTRAVKGGLSVEFEGVRGFIPASMLDTRFVRNAERFVGQEFDTKIKE
                     VNAKENRFILSRREVVEAATAAARAEVFGKLAVGDVVTGKVARITSFGAFIDLGGVDG
                     LVHLTELSHERNVSPKSVVTVGEEIEVKILDLNEEEGRVSLSLKATVPGPWDGVEQKL
                     AKGDVVEGTVKRLTDFGAFVEVLPGIDGLVHVSQISHKRIENPKEALKVGQEVQVKVL
                     EVNADAERVSLSIKALEERPAQEEGQKEEKRAARPRRPRRQEKRDFELPETQTGFSMA
                     DLFGDIEL"
     gene            12366..12863
                     /locus_tag="VQ543_000657"
     CDS             12366..12863
                     /locus_tag="VQ543_000657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000920162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GAF domain-containing protein"
                     /protein_id="HET2611424.1"
                     /translation="MLKSEKQSRYQMLNEELSFLLEGETNVLANLSNASALIKSRFPN
                     TVFAGFYLFDGKELVLGPFQGGVSCIRIALGKGVCGEAAHFQETVIVGDVTTYLNYIS
                     CDSLAKSEIVVPMMKNGQLLGVLDLDSSEIEDYDAMDRDYLEQFVAILLEKTTWDFTM
                     FEEKS"
     gene            12863..14518
                     /gene="dnaX"
                     /locus_tag="VQ543_000658"
     CDS             12863..14518
                     /gene="dnaX"
                     /locus_tag="VQ543_000658"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000283769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit gamma/tau"
                     /protein_id="HET2611425.1"
                     /translation="MYQALYRKYRSQNFSQLVGQEVVAKTLKQAVEQEKISHAYLFSG
                     PRGTGKTSVAKIFAKAMNCPNQVGGEPCNNCYICQAVTDGSLEDVIEMDAASNNGVDE
                     IREIRDKSTYAPSLARYKVYIIDEVHMLSTGAFNALLKTLEEPTQNVVFILATTELHK
                     IPATILSRVQRFEFKSIKTQDIKEHIHYILEKENISSEPEAVEIIARRAEGGMRDALS
                     ILDQALSLTQGNELTTAISEEITGTISLSALDDYVAALSQQDVPKALSCLNLLFDNGK
                     SMTRFVTDLLHYLRDLLIVQTGGENTHHSSVFVENLALPQKNLFEMIRLATVSLADIK
                     SSLQPKIYAEMMTVRLAEIKPEPALSGAVENEIATLRQEVARLKQELSNVGAVPKQVA
                     PAPSRPATGKTVYRVDRNKVQSILQEAVENPDLARQNLIRLQNAWGEVIESLGGPDKA
                     LLVGSQPVAANEHHAILAFESNFNAGQTMKRDNLNTMFGNILSQAAGFSPEILAISME
                     EWKEVRAAFSAKAKSSQTEKEVEESLIPEGFEFLADKVKVEED"
     gene            14546..14740
                     /locus_tag="VQ543_000659"
     CDS             14546..14740
                     /locus_tag="VQ543_000659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001041548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3272 domain-containing protein"
                     /protein_id="HET2611426.1"
                     /translation="MNKQQFIIMALFTAAETYFFNEAWMTGRYIMAAFWAILLFRNFR
                     VSYVMGKIVDVIDQHFNRKD"
     gene            14890..15660
                     /gene="sufC"
                     /locus_tag="VQ543_000660"
     CDS             14890..15660
                     /gene="sufC"
                     /locus_tag="VQ543_000660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000114488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly ATPase SufC"
                     /protein_id="HET2611427.1"
                     /translation="MSVLEIKDLHVEIEGKEILKGVNLTLKTGEIAAIMGPNGTGKST
                     LSAAIMGNPNYEVTKGEVLFDGVNILELEVDERARMGLFLAMQYPSEIPGITNAEFLR
                     AAMNAGKEDDEKISVREFITRLDEKMELLNMKEEMAERYLNEGFSGGEKKRNEILQLL
                     MLEPTFALLDEIDSGLDIDALKVVSKGVNAMRGEGFGAMIITHYQRLLNYITPDVVHV
                     MMEGRVVLSGGPELAARLEREGYAKLAEELGYDYKEEL"
     gene            15688..16950
                     /gene="sufD"
                     /locus_tag="VQ543_000661"
     CDS             15688..16950
                     /gene="sufD"
                     /locus_tag="VQ543_000661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufD"
                     /protein_id="HET2611428.1"
                     /translation="MTRENIKLFSEMHAEPSWLADLRQKAFDKIETLELPVIERVKFH
                     RWNLGDGTITENEPSANVPDFTALDHHLKLVQVGTQTVFEQTPVELAEQGVVFTDFHS
                     ALEEIPELIEEFFMSSVKYDDDKLAAYHTAYFNSGAVLYIPDNVEITEPIEGIFYQDS
                     DSNVPFNKHIMIIAGKNSKINYLERLESRGEGSAKATANITVEVIARSGAQVKFAAID
                     RLGENVTAYISRRGKLGNDASIDWAIGVMNEGNVVADFDSDLIGNGSYADLKVVALSS
                     GRQVQGIDTRVTNYGCNSIGNILQHGVILEKATLTFNGIGHIIKGAKGADAQQESRVL
                     MLSDQARSDANPILLIDENDVTAGHAASIGQVDPEDMYYLMSRGLDKATAERLVVRGF
                     LGSVIVEIPVKEVRDEMIATIEEKLSKR"
     gene            16961..18187
                     /locus_tag="VQ543_000662"
     CDS             16961..18187
                     /locus_tag="VQ543_000662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000887707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HET2611429.1"
                     /translation="MLDVEAIRKDFPILDQIVNDEPLVYLDNAATTQKPLVVLKAINS
                     YYEQDNANVHRGVHTLAERATASYEAARETIRKFINAGSTKEVLFTRGTTTSLNWVAR
                     FAEEILTEGDQVLISVMEHHSNIIPWQEACRKTGAELVYVYLKDGALDMEDLRAKLTD
                     KVKFVSLAHASNVLGVVNPIKEITQLAHQVGAIMVVDGAQSTPHMKIDVQDLDLDFFA
                     FSGHKMAGPTGIGVLYGKEKYLEQMSPVEFGGEMIDFVYEQSASWKELPWKFEAGTPN
                     MAGAIGLATAVDYLEKIGMDAVEAHEQELIAYVYPKLQAIEGLTIYGSQDLAQRSGVI
                     AFNLGDLHPHDLATALDYEGVAVRAGHHCAQPLLQYLEVPASARASFYIYNTKADCDK
                     LVDALQKTKEFFNGTF"
     gene            18174..18614
                     /locus_tag="VQ543_000663"
     CDS             18174..18614
                     /locus_tag="VQ543_000663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SUF system NifU family Fe-S cluster assembly
                     protein"
                     /protein_id="HET2611430.1"
                     /translation="MALSKLDSLYMAVVADHSKNPHHQGKLEDAEQISLNNPTCGDVI
                     NLSVKFDAEDRLEDIAFLNSGCTISTASASMMTDAVLGKTKQEILELATIFSEMVQGQ
                     KDERQDQLGDAAFLSGVAKFPQRIKCATLAWNALKKTIENQEKQ"
     gene            18664..20076
                     /gene="sufB"
                     /locus_tag="VQ543_000664"
     CDS             18664..20076
                     /gene="sufB"
                     /locus_tag="VQ543_000664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufB"
                     /protein_id="HET2611431.1"
                     /translation="MAEERVEPKPIDLGEYKFGFHDDVEPVLSTGKGLNEGVIRELSA
                     AKGEPEWMLEFRLKSYETFKKMPMQTWGADLSEIDFDDLIYYQKPSDKPARSWDDVPE
                     KIKETFERIGIPEAERAYLAGASAQYESEVVYHNMKEEFQKLGIIFTDTDSALKEYPD
                     LFKQYFAKLVPPTDNKLAALNSAVWSGGTFIYVPKGVKVDIPLQTYFRINNENIGQFE
                     RTLIIVDEGASVHYVEGCTAPTYSSNSLHAAIVEIFALDGAYMRYTTIQNWSDNVYNL
                     VTKRAKAQKDATVEWIDGNLGAKTTMKYPSVYLDGEGARGTMLSIAFANAGQHQDTGA
                     KMIHNAPHTSSSIVSKSIAKGGGKVDYRGQVTFNKNSKKSVSHIECDTIIMDDLSASD
                     TIPFNEIHNSQVALEHEAKVSKISEEQLYYLMSRGLSESEATEMIVMGFVEPFTKELP
                     MEYAVELNRLISYEMEGSVG"
     gene            complement(20307..21548)
                     /locus_tag="VQ543_000665"
     CDS             complement(20307..21548)
                     /locus_tag="VQ543_000665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HET2611432.1"
                     /translation="MKKIFLTLLTVSLLGGASTAVAQDFTIAAKHAIAVEANTGKILY
                     EKDATQPVEIASITKLITAYLVYEALENGSITLSTPVDISDYPYQLTTNSEASNIPME
                     ARNYTVEELLEATLVSSANSAAIALAEKIAGSEKDFIDMMRAKLLEWGIQDATVVNTT
                     GLNNETLGDNIYPGSKKDEENKLSAYDVAIVARNLIKKYPQVLEITKKPSSTFAGMTI
                     TSTNYMLEGMPAYRGGFDGLKTGTTDKAGESFVGTTVEKGMRVITVVLNADHQDNNPY
                     ARFTATSSLMDYISSTFTLRKIVQQGDAYQDSKAPVQDGKEDTVTAVAPEDIYLIERV
                     GNQSSQSVQFTPDSKAIPAPLEAGTVVGHLTYEDKDLIGQGYITTERPSFEMVADKKI
                     EKAFFLKVWWNQFVRFVNEKL"
     gene            21651..22760
                     /locus_tag="VQ543_000666"
     CDS             21651..22760
                     /locus_tag="VQ543_000666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000489839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HET2611433.1"
                     /translation="MFRRNKLFFWTTEILLLTIIFYLWRQMGSLINPFVSVLNTIMIP
                     FLLGGFLYYLTNPIVTFLNKVCKLNRLLGILITLCTLVWGMVIGVVYLLPILINQLSS
                     LIISSQTIYSRVQDLIIDLSNYPALQNLDVEATIQQLNLSYVDILQNILNSVSNSVGS
                     VLSALISTVLILIMTPVFLVYFLLDGHKFLPMLERTILKRDRLHIAGLLKNLNATIAR
                     YISGVSIDAIIIGCLAYIGYSIIGLKYALVFAIFSGVANLIPYVGPSIGLIPMIIANI
                     FTDPHRLLIAVIYMLVVQQVDGNILYPRIVGSVMKVHPITILVLLLLSSNIYGVVGMI
                     VAVPTYSILKEISKFLSRLYENHKIMKERERELAK"
     gene            23294..23641
                     /gene="ssrA"
                     /locus_tag="VQ543_000667"
     tmRNA           23294..23641
                     /gene="ssrA"
                     /locus_tag="VQ543_000667"
                     /product="transfer-messenger RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00023"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00023"
     gene            complement(23824..23911)
                     /locus_tag="VQ543_000668"
     tRNA            complement(23824..23911)
                     /locus_tag="VQ543_000668"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(23875..23877),aa:Ser,seq:gga)
     gene            24073..24813
                     /locus_tag="VQ543_000669"
     CDS             24073..24813
                     /locus_tag="VQ543_000669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000920650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HET2611434.1"
                     /translation="MLKTERKQLILEELNQHHVVSLEKLVSLLETSESTVRRDLDELE
                     AENKLRRVHGGAELPHSLQEEETIQEKSVKNLQEKKLLAQKAASLIKEKDVIFIDAGT
                     TTAFLIHELVNKNITVVTNSIHHAAQLVEKQIPTVMVGGNVKTATDASIGGVALNQIN
                     QLHFDRAFIGMNGVDDGYYTTPDMEEGAVKRAILENAKQTYVLVDSSKIGQTCFAKVA
                     PLKRAIVITSQGHELLQVIKEKTEVIEV"
     gene            24810..25721
                     /gene="pfkB"
                     /locus_tag="VQ543_000670"
     CDS             24810..25721
                     /gene="pfkB"
                     /locus_tag="VQ543_000670"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015605104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HET2611435.1"
                     /translation="MIYTVTLNPSIDYIVRLDQVKVGSVNRMDSDDKFAGGKGINVSR
                     VLKRLNIPNTATGFIGGFTGKFITDTLAEEEIETRFVQVAEDTRINVKIKADQETEIN
                     GTGPTVESVQLEELKAILSSLTAEDTVVFAGSSAKNLGNVIYKDLISLTRQTGAQVVC
                     DFEGQTLIDSLDYQPLLVKPNNHELGAIFGVKLESLDEIEKYARELLAKGAQNVIISM
                     AGDGALLVTSEGAYFAKPIKGTVKNSVGAGDSMVAGFTGEFVKSKDVVEAFKWGVACG
                     TATTFSDDLATAEFIKETYGKVEVEKR"
     gene            25718..27670
                     /locus_tag="VQ543_000671"
     CDS             25718..27670
                     /locus_tag="VQ543_000671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HET2611436.1"
                     /translation="MKIQDLLRKDVMLLDLQATEKTAVIDEMIKNLTDHGYVTDFETF
                     KEGILAREALTSTGLGDGIAMPHSKNAAVKEATVLFAKSNKGVDYESLDGQATDLFFM
                     IAAPEGANDTHLAALAELSQYLMKDGFADKLRQATSADQVIELFDQASEKTEELVQAP
                     ANDSGDFIVAVTACTTGIAHTYMAQEALQKVAAEMGVGIKVETNGASGVGNQLTAEDI
                     RKAKAIIIAADKAVEMDRFDGKPLINRPVADGIRKTEELINLALSGDTEVYRAANGAK
                     AATASNEKQSLGGALYKHLMSGVSQMLPFVIGGGIMIALAFLIDGALGVPNENLGNLG
                     SYHELASMFMKIGGAAFGLMLPVFAGYVAYSIAEKPGLVAGFVAGAIAKEGFAFGKIP
                     YAAGGEATSTLAGVSSGFLGALVGGFIAGALVLAIKKYVKVPRSLEGAKSILLLPLLG
                     TILTGFVMLAVNIPMAAINTAMNDFLGGLGGGSAVLLGIVLGGMMAVDMGGPVNKAAY
                     VFGTGTLAATVSSGGSVAMAAVMAGGMVPPLAIFVATLLFKDKFTKEERNSGLTNIIM
                     GLSFITEGAIPFGAADPARAIPSFILGSAVAGGLVGLTGIKLMAPHGGIFVIALTSNA
                     LLYLVSVLVGAIVSGVVYGYLRKPQA"
     gene            27834..30059
                     /locus_tag="VQ543_000672"
     CDS             27834..30059
                     /locus_tag="VQ543_000672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000908822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HET2611437.1"
                     /translation="MLISLGIAILLIFAAFKLGAAGITLYNLIRLLVGSLAYLAIFGL
                     LIYLFFFKWIRKQEGLLSGFFTIFAGLLLIFEAYLVWKYGLDKSVLKGTMAQVVTDLT
                     GFRTTSFAGGGLIGVALYIPTAFLFSNIGTYFIGSILILVGSLLVSPWSVYDIAEFFS
                     RGFAKWWEGHERRKEERFVKQEEKARQKAEKEARLEQEETEKALLDLPPVDMETGEIL
                     TEEAVQNLPPIPEEKWVEPEIILPQAELKFPEQEDDSDDEDVQVDFSAKEALEYKLPS
                     LQLFAPDKPKDQSKEKKIVRENIKILEATFASFGIKVTVERAEIGPSVTKYEVKPAVG
                     VRVNRISNLSDDLALALAAKDVRIEAPIPGKSLIGIEVPNSDIATVSFRELWEQSQTK
                     AENFLEIPLGKAVNGTARAFDLSKMPHLLVAGSTGSGKSVAVNGIIASILMKARPDQV
                     KFMMVDPKMVELSVYNDIPHLLIPVVTNPRKASKALQKVVDEMENRYELFAKVGVRNI
                     AGFNAKVEEFNSQSEYKQIPLPFIVVIVDELADLMMVASKEVEDAIIRLGQKARAAGI
                     HMILATQRPSVDVISGLIKANVPSRVAFAVSSGTDSRTILDENGAEKLLGRGDMLFKP
                     IDENHPVRLQGSFISDDDVERIVNFIKTQADADYDESFDPGEVSENEGEFSDGDAGGD
                     PLFEEAKSLVIETQKASASMIQRRLSVGFNRATRLMEELEIAGVIGPAEGTKPRKVLQ
                     Q"
     gene            complement(30104..30532)
                     /locus_tag="VQ543_000673"
     CDS             complement(30104..30532)
                     /locus_tag="VQ543_000673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000073927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2611438.1"
                     /translation="MSNYRRTSKPKTEHIKKGFTVFQKTVATIASILGLITASITIMN
                     ALDNNKNIKKEPTTSQTTTIVKEIQKESPKENTSPTKETNTSQEKTQQEETPKSSVKE
                     EKKEDQKTATQDSSTPASSKPATENEKQSNAPTSENKSNQ"
     gene            30670..31812
                     /locus_tag="VQ543_000674"
     CDS             30670..31812
                     /locus_tag="VQ543_000674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000638948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HET2611439.1"
                     /translation="MIYFDNSATTKPYPEALETYMQVASKILGNPSSLHRLGDQATRI
                     LDASRQQIADLIGKKSDEIFFTSGGTEGDNWLIKGVAFEKAQFGKHIIVSAIEHPAVK
                     ESALWLKSQGFEVDFAPVDKKGLVDVEALAGLIRHDTILVSIMAVNNEIGSIQPIEAI
                     SEFLADKPTISFHVDAVQALAKIPTEKYLTERVDCATFSSHKFHGVRGVGFVYIKSGK
                     KITPLLTGGGQERDYRSTTENVAGIAATAKALRLSMEKLDIFRSKTGQMKAVIRQALL
                     NYPDIFVFSDEENFAPHILTFGIKGVRGEVIVHAFEDYDIFISTTSACSSKAGKPAGT
                     LIAMGVDKDKAKSAVRLSLDLENDMSQVEQFLTKLKLIYNQTRKVR"
     gene            31821..33035
                     /gene="thiI"
                     /locus_tag="VQ543_000675"
     CDS             31821..33035
                     /gene="thiI"
                     /locus_tag="VQ543_000675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001200101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 4-thiouridine(8) synthase ThiI"
                     /protein_id="HET2611440.1"
                     /translation="MQYSEIMIRYGELSTKGKNRMRFINKLRNNISDVLSIYTQVKVT
                     ADRDRAHAYLNGADYTAVAESLKQVFGIQNFSPVYKVEKSVEVLKSSVQEIMRDIYKE
                     GMTFKISSKRSDHNFELDSRELNQTLGGAVFEAIPNVQVQMKSPDINLQVEIREEAAY
                     LSYETIRGAGGLPVGTSGKGMLMLSGGIDSPVAGYLALKRGVDIEAVHFASPPYTSPG
                     ALKKAQDLTRKLTKFGGNIQFIEVPFTEIQEEIKAKAPEAYLMTLTRRFMMRITDRIR
                     EVRNGLVIINGESLGQVASQTLESMKAINAVTNTPIIRPVVTMDKLEIIDIAQEIDTF
                     DISIQPFEDCCTIFAPDRPKTNPKIKNAEQYEARMDVEGLVERAVAGIMITEITPQAE
                     KDEVDDLIDNLL"
     gene            33170..33994
                     /locus_tag="VQ543_000676"
     CDS             33170..33994
                     /locus_tag="VQ543_000676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001076725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HET2611441.1"
                     /translation="MNQSYFYLKMKEHKLKVPYTGKERRVRILLPKDYEKDTDRSYPV
                     VYFHDGQNVFNSKESFIGHSWKIIPAIKRNPDISRMIVVAIDNDGMGRMNEYAAWKFQ
                     ESPIPGQQFGGKGVEYAEFVMEVVKPFIDETYRTKADCQHTAMIGSSLGGNITQFIGL
                     EYQDQIGCLGVFSSANWLHQEAFNRYFECQKLSPDQRIFIYVGTEEADDTDKTLMDGN
                     IKQAYIDSSLCYYHDLIAGGVHLDNLVLKVQSGAIHSEIPWSENLPDCLRFFAEKW"
     gene            34016..34755
                     /locus_tag="VQ543_000677"
                     /pseudo
     CDS             34016..34755
                     /locus_tag="VQ543_000677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000546805.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
     gene            34768..35934
                     /locus_tag="VQ543_000678"
     CDS             34768..35934
                     /locus_tag="VQ543_000678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001108652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="HET2611442.1"
                     /translation="MNYLVISPYYPQNFQQFTIELANKGITVLGIGQESYEQLDEPLR
                     NSLTEYFRVDNLENIDEVKRAVAFLFYKHGPIGRIESHNEYWLELDATLREQFNVFGA
                     KPEDLKKTKYKSEMKKLFKKAGVPVVPGAVIKTEADVDQAVKEIGLPMIAKPDNGVGA
                     AATFKLETEDDINHFKQEWDHSTLYFFEKFVTSSEICTFDGLVDKDGKIVFSTTFDYA
                     YTPLDLMIYKMDNSYYVLKDMDPKLRKYGEAIVKEFGMKERFFHIEFFREGDDYITIE
                     YNNRPAGGFTIDVYNFAHSLDLYRGYAAIVAGEEFPASDFETQYCLATSRRANAHYVY
                     SEEDLLAKYSQQFKVKKVMPAAFAELQGDYLYMLTTPSRQEMEQMIADFGQRQE"
     gene            36442..37935
                     /locus_tag="VQ543_000679"
     CDS             36442..37935
                     /locus_tag="VQ543_000679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000627753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent DNA methyltransferase"
                     /protein_id="HET2611443.1"
                     /translation="MITGELKNKIDQLWEILWTEGNANPLTNIEQLTYLLFMKDLDSV
                     ELGRESDAEFLGIPYEGVFPKDKPEYRWSTFKNIGDAQEVYRLMTQEIFPFIKNLKGD
                     TDDTAFSRYMREAIFQINKPATLQKAISILDVFPTRGLDVDFDNDKQSITDIGDIYEY
                     LLSKLSTAGKNGQFRTPRHIIDMMVELMQPTIKDIISDPAMGSAGFLVSASRYLKRKK
                     DEWETNTDNINHFHNQMFHGNDTDTTMLRLGAMNMMLHGVENPQISYLDSLSQDNEEA
                     DKYTLVLANPPFKGSLDYNSTSNDLLATVKTKKTELLFLSLFLRTLKPGGRAAVIVPD
                     GVLFGSSKAHKGIRQEIVENHKLDAVISMPSGVFKPYAGVSTAILIFTKTGNGGTDKV
                     WFYDMKADGLSLDDKRQPISDNDIPDIIERFHHLEKEAERQRTDQSFFVPVAEIKEND
                     YDLSINKYKEIEYEKVEYEPTEVILKKINDLEKEIQAGLAELEKLLK"
     gene            37948..38994
                     /locus_tag="VQ543_000680"
     CDS             37948..38994
                     /locus_tag="VQ543_000680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000756103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HET2611444.1"
                     /translation="MKKVKLGEVLSLKKGKKATVLAEQTTLSQRYIQIDDLRNNNNLK
                     FTESLNMTEALPDDILIAWDGANAGTVGYGLSGAVGSTITVLKKNERYKEKIISDYLG
                     VFLESKSQYLREHSTGATIPHLNKNILLDLQLELLGIEEQENIICILNTIKRLITKRK
                     LQLDELNLLVKSRFNEMFGDVILNEKEWKVSKWNEILTIRNGKNQKQVEDADGKFPIY
                     GSGGIMGYAKDWIVKKNSVIIGRKGNINKPILVRENFWNVDTAFGLEPVLEKINSEYL
                     FYFCQLYNFEKLNKAVTIPSLTKSDLLNISIPLPPLALQNEFADFVALVDKSQFACEI
                     AIKVWRNSLKFSII"
     gene            39024..41720
                     /locus_tag="VQ543_000681"
                     /pseudo
     CDS             39024..41720
                     /locus_tag="VQ543_000681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000526318.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
     gene            complement(41754..>42638)
                     /locus_tag="VQ543_000682"
     CDS             complement(41754..>42638)
                     /locus_tag="VQ543_000682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001856869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HET2611445.1"
                     /translation="HQLAISTSTVIRKLNDFHFEHDFSRLPKIMSWDEYAFTKGKMSF
                     IAQDFDNLNIITVLEGRTQAVIRNHFLRYDRAVRCQVKIITMDMFSPYYDLAKQLFPC
                     AKIVLDRFHIIQHLSRAMSRFRVQIMNQFERKSHEYKAIKRYWKLIQQDSRKLSDKRF
                     YRPTFRMHLTNKEILDKILSYSEDLKHHYQIYQLLLFHFQNKDPEKFFGLIEDNLKQV
                     HPLFQTVFKTFLKNKEKIVNALQLHYSNAKLEATNNLIKLIKRNAFGFRNFENFKKRI
                     FIALNIKKERTKFVLSQA"
BASE COUNT        12942 a         7654 c         9439 g        12603 t
ORIGIN      
        1 ttaacagcga aattatcgcc tataatcttt caacttcgcc caacttagaa caagtataaa
       61 caatgttgga acaggcattc aaagagaagc actacgagaa tacgattctc catagtgacc
      121 aaggctggca atatcaacac gattcttatc atcagttcct agagagtaag ggaattcaag
      181 catccatgtc acgtaaggga aacagcccag acaatggtat gatggagtcc ttctttggga
      241 ttctgaaatc ggaaatgttt tacggttatg agaagtcgtt tcagtcgctt aagcaattgg
      301 aacaagccat tatagactat attgattact acaacaataa acgaattaag ataaaactaa
      361 aaggacttag ccctgtgcaa tacagaacta aatccttcgg ataaattaat tgtctaactt
      421 ttggggtgca gttcacagaa ctggcatttt attttttagg atcttgatgg gttaggttca
      481 atccccaagg gaccaaattt tcagttttat ttttgatacg agctatattg tccttatgac
      541 gaatgataat caaactagca agtgctaaga taatagcgat gaagagagag tcatagttac
      601 tcaggataaa accaaaaagt ggaaagagca gaaccccgat aacagccgcg atcgatgctg
      661 tgacactaga cagtgaaatc atactgccaa gatagagagc tccaaagaag ataatcgcaa
      721 ggtagagaca gaagataggc gcaaatccga aaattactcc agcactggtt gcgacagcct
      781 taccaccttt aaatcctgca aagataggga aggtatggcc gataacagcc aaaagtccaa
      841 agatgagagg agaaacgcct tgtagatgaa aaataatcgg aagcagcgtt gctagggttc
      901 ctttgaaaaa gtcaatcaca aaggttgcca taccagcttt cttacctaaa atgcggaagg
      961 tattggtcgt tccagtgtta ccagaaccat gctcgcgtag attgatttga aagaatactt
     1021 gtccaatcca gagaccagat ggaatcgaac ccagcagata ggctaggatt aataaaacta
     1081 ttgtaatcat actcctatta tatcatgaat tgggaaagaa aagcagagaa tctctgctaa
     1141 aattgtcaca tcggagaaag aaaaattttg caaaatcctt ggaaaacctg tagaatagta
     1201 aagatgaacg aataggaggt tccttgtgtc aaaaaaggaa atcaatatta acaattataa
     1261 tgatgatgct attcaggtgc tagaagggtt ggatgcggtc cgaaaacgtc cagggatgta
     1321 tattggatcg accgatggcg ctggtcttca tcacctagtt tgggaaatcg ttgataatgc
     1381 agtcgatgaa gccttgtctg ggtttggtga tcgtatcgat gtaaccatca ataaagacgg
     1441 tagtctaacg gttcaagacc atggacgtgg gatgccgaca ggtatgcacg ctatgggaat
     1501 tccaactgtt gaggttatct ttaccattct tcatgccgga gggaaattcg gtcaaggtgg
     1561 ctataagaca tcaggtggac ttcacggagt gggttcttcc gttgttaacg ccctttctag
     1621 ctggttagaa gttgaaatta cccgtgatgg cgcagtttac aagcaacgtt tcgaaaatgg
     1681 tggaaaacct gtcacgactt tgaagaaaat cggtacagca cccaagtcta aaacaggcac
     1741 caaagttact tttatgcctg acgcgactat attttctacg acagatttca agtacaatac
     1801 catttcagag cgccttaatg aatcagcctt tctcttgaaa aatgtgacct tgtctttaac
     1861 ggacaagcga acagatgaag cgattgagtt ccactatgag aatggagtac aagattttgt
     1921 ttcttatctc aacgaagata aggaaatctt gacgccagtt ctttactttg aaggggaaga
     1981 caatggtttt caagtggaag tagccctcca gtacaatgac ggattctcag ataacattct
     2041 atcctttgtc aataacgttc gcaccaagga cggtggaacg cacgagacag gactcaagtc
     2101 tgccattacc aaggtcatga atgactatgc acgtaaaaca ggtcttctca aggaaaaaga
     2161 taaaaacctt gaaggttcag actatcgtga gggactagcg gccgttcttt ctatcttagt
     2221 tcctgaagaa cacttgcagt ttgaaggaca gaccaaggat aaactaggaa gccccctagc
     2281 tcgcccagtt gtggatggaa tagtggctga taagttgacc tttttcctta tggaaaatgg
     2341 ggaattagct tctaacctca tccgcaaggc tatcaaggcc cgtgatgctc gtgaagcagc
     2401 acgtaaggcg cgtgatgaga gccgaaatgg gaagaaaaac aagaaagata agggcttgtt
     2461 gtctgggaaa ttgaccccag cccaatctaa gaatcctgct aagaatgaac tctatctagt
     2521 tgagggggac tctgccggtg gttctgccaa acaaggtcgt gaccgcaagt tccaggctat
     2581 tctacctctt cgtggtaagg ttatcaatac agccaaggcc aagatggcgg atatcctcaa
     2641 aaatgaagag atcaatacca tgatttatac cattggtgcg ggtgttggag cagacttctc
     2701 tattgaagat gccaactatg ataagatcat tatcatgacc gatgcggata ccgacggtgc
     2761 ccatatccag accttgctct tgacattttt ctaccgttac atgcgtccgc tagtcgaggc
     2821 aggtcatgtc tatattgccc tcccacctct ttacaagatg tccaaaggta aaggaaagaa
     2881 agaagaagtg gcctacgctt ggacggacgg agaactagaa gaactccgta aacagttcgg
     2941 taaaggcgct accctccaac gatacaaagg acttggtgag atgaatgcgg accagctctg
     3001 ggaaacaacc atgaacccag aaacacgtac cctcatccgt gtcacaattg aagatttagc
     3061 gcgcgccgaa cgccgcgtca atgttctcat gggagataag gtagaaccac gccgtaaatg
     3121 gattgaagat aatgtcaagt ttacgctaga agaagcgaca gtgttttaat gaaagaaaat
     3181 aatatgttag taaactggaa attagagtcg gatgtgaatg actatgtgaa aaagcagttt
     3241 gaaaatcttg gtttgaaaaa attgcaggat tattaatgaa gaatctgcta tgagtgctta
     3301 tctcaaagag gcgcttaagg gagcggctaa gacacaaact aagactaatt ttggaaaacc
     3361 agattttcat attgaaaaat acaaacagga tagtttggtt acttatcgta actgaacacg
     3421 ggaggaattc ccgtaaaata tcttttactg cataaaaacc tactctacat tctttgaaag
     3481 gagttgaaca cgccctagat actgtgtgaa aaagataaat tctcttgtga gtttgcttac
     3541 ttcaagaatt ttctattttc acttggtatt ttatgggctt tgtatcttat gtctaacatt
     3601 caaaacatgt ccctggagga catcatggga gagcgctttg gtcgctactc caagtacatt
     3661 attcaagacc gggctttgcc agatattcgt gatgggttga agccggttca gcgccgtatt
     3721 ctttattcta tgaataagga tagcaatact tttgacaaga gctaccgtaa gtcggccaag
     3781 tcagtcggga acatcatggg gaatttccac ccacacgggg attcttctat ctatgatgcc
     3841 atggttcgta tgtcacagaa ctggaaaaat cgtgagattc tagttgaaat gcacggtaat
     3901 aacggttcta tggacggaga tcctcctgcg gctatgcgtt atactgaggc acgtttgtct
     3961 gaaattgcag gttaccttct tcaggatatc gagaaaaata cagttccttt tgcatggaac
     4021 tttgacgata cggagaaaga accaacggtc ttgccagcag cctttccaaa cctcttggtc
     4081 aatggttcga ctgggatttc ggctggttat gccacagaca ttcctcccca taatttagct
     4141 gaggtcatag atgctgcagt ttacatgatt gaccacccaa ctgcaaagat tgataaactc
     4201 atggaattct tgcctggacc agacttccct acaggggcta ttattcaggg tcgtgatgaa
     4261 atcaagaaag cttatgagac tgggaaaggg cgcgtggttg ttcgttccaa gactgaaatt
     4321 gaaaagctaa aaggtggtaa ggaacaaatc gttattactg agattcctta tgaaatcaat
     4381 aaggccaatc tagtcaagaa aatcgatgat gttcgtgtta ataacaaggt agctgggatt
     4441 gctgaggttc gtgatgagtc tgaccgtgat ggtcttcgta tcgctatcga acttaagaaa
     4501 gacgctaata ctgagcttgt tctcaactac ttatttaagt acaccgacct acaaatcaac
     4561 tacaacttta atatggtggc gattgacaat ttcacacctc gtcaggttgg gattgttcca
     4621 atcctgtcta gctacatcgc tcaccgtcga gaagtgattt tggcgcgttc acgctttgac
     4681 aaagaaaagg ctgagaaacg tctccatatc gtcgaaggtt tgattcgtgt gatttcgatt
     4741 ttggatgaag tcattgctct tatccgtgct tctgagaata aggcggacgc caaggaaaac
     4801 ctcaaagtta gctatgattt tacggaagaa caggctgagg ctatcgtaac tttgcaactg
     4861 taccgtttga ccaataccga tgtggttgtc ttgcaggaag aagaagcaga gcttcgtgag
     4921 aagattgcta tgctggcggc tattatcggt gatgaaagga ctatgtacaa tctcatgaag
     4981 aaagaacttc gtgaggtcaa gaagaaattt gcaactcctc gtttgagttc tttagaagac
     5041 actgcgaaag caattgagat tgatacagct agtcttatcg ctgaggaaga tacctacgtc
     5101 agcgtgacca aggcaggtta catcaagcgt accagtccac gttcctttgc ggcttccacc
     5161 ttggaagaaa ttggcaagcg tgatgatgac cgtttgattt ttgttcaatc tgccaagaca
     5221 acccagcacc tcttgatgtt cacaagtctt ggaaatgtca tctacagacc aatccatgag
     5281 ttggcagata ttcgttggaa ggacatcgga gagcatctga gccaaaccat cacaaacttt
     5341 gaaacgaatg aagaaatcct ttatgtggaa gtactggatc agtttgacga tgcgacaacc
     5401 tactttgcag tgactcgcct tggtcaaatc aaacgggtag agcgaaaaga attcactcca
     5461 tggcggacct atagatctaa gtctgtcaag tatgctaagc tcaaagacga tacagatcag
     5521 attgtagcag tggctccgat taaactagat gatgttgtct tggttagtca aaatggttat
     5581 gccctgcgtt tcaatatcga agaggttccg gttgtcggtg ctaaggcagc aggtgtcaag
     5641 gctatgaatt tgaaagaaga tgatgtcctc caatctggct ttatctgtaa tacttcgtcc
     5701 ttctacctct tgacccagcg tggaagcttg aaacgtgttt ctattgagga aattctagca
     5761 accagccgtg ccaaacgagg attacaagtc ttgcgtgagt tgaaaaacaa accgcatcgt
     5821 gtcttcttgg caggagcagt tgcagagcaa ggatttgttg gcgatttctt cagtacggaa
     5881 gtggatgtga acgaccaaac tctgcttgtc caatccaata aaggaacaat ctatgaaagc
     5941 cgattgcaag acttgaactt gtcagaacgc actagcaatg gaagcttcat ttctgacacg
     6001 atttcagatg aagaagtttt tgacgcttat cttcaggaag tagttactga agataaataa
     6061 gtgaaatgaa gaatcagttc taagagctgg tttttattgg agaaattttc tgaaaattac
     6121 aaaatatact tgctatttta gaaaaatagt gtagaatata agaaataggt ttttagaata
     6181 aggagtggaa tatgacagta acgattgatt gggaaaacct cggtttttcc tatatgaaat
     6241 taccttatcg ctatcttgct catttcaaaa atggacaatg ggatcaagga gagcttacag
     6301 aggatgcaac tttgcatatt tcagagtctt ctccaagtct tcactatgga caacaagcat
     6361 ttgaaggttt gaaagcttat cgtactaagg atggcagtgt tcaactgttc cgtcctgatg
     6421 aaaatgctaa acgtctgcaa cgtacatgtg accgtctctt gatgccacaa gttccgacag
     6481 acatgtttgt agaagcttgt aaagcagttg tccgtgcgaa tgaagaatac gtaccaccat
     6541 acggaacagg tggaacctta tatcttcgcc ctcttttgat tggtgtcgga gatattatcg
     6601 gggtaaaacc ggcagaagag tacattttca ccatctttgc tatgccagtt ggaaattact
     6661 ttaaaggtgg tttggtccca accaacttct tgattcagga tgagtacgac cgtgcagcac
     6721 caaatggtac aggtgcggct aaggttggtg gaaactatgc tgcaagtctc ttaccaggaa
     6781 aaatggccaa gtcacgtcat ttctcagatg ttatctatct ggacccatca actcatacaa
     6841 agattgaaga agtcggatca gctaacttct ttggaattac agctgataat gaatttgtaa
     6901 caccattgag tccatctatc ttgccatcta ttaccaagta ttccttgctt tatttggcag
     6961 aacatcgctt gggattaact cctattgagg gtgatgttcc aattgataat cttgaccgtt
     7021 ttgtagaggc aggtgcctgt ggtacagcag cggttatttc tccaattgga ggtattcaac
     7081 atggtgatga tttccatgta ttctatagtg aaacagaagt aggtcctgtg acgcgtaaat
     7141 tatataatga attgacgggt attcagtttg gcgatattga agcgccagaa ggttggattg
     7201 taaaagtaga ttaaaataaa ccaaaggaga ttttttatga aatagaaaaa gtggctctta
     7261 acagcaggag tggtcctgag cacgtcagct attttagtgg cttgtggaaa aactgataaa
     7321 gaagcagatg caccgacaac attttcttat gtctatgcag tagatccagc atcattgggc
     7381 tacagtatag cgactcgaac atcgaggaca gacgttattg gaaatgttat tgatggtttg
     7441 atggaaaatg ataaatacgg caatgttgct ccttctcaaa aagactatga tttgaacagt
     7501 acaggatggg ctccaagcta tcaagatcca gcgtcttact tgaatattat ggatccaaaa
     7561 tctggttctg acatgaaaca ccttggcatt acgaaaggaa aagataagga tgttgtagct
     7621 aaacctggtt tggataaata taagaaattg ttagaagatg ctgtttctga gaccactgac
     7681 ctagagaaga gatatgaaaa atatgccaaa gctcaagctt ggtcgacaga tagttcatta
     7741 ttgatgccaa cagcttcatc tggtggtttt ccagttgtaa gtaacgtagt accattctca
     7801 aaaccatact cacaagttgg tattaagggg gaaccatata tctttaaagg aatgaaattg
     7861 caaaaagata ttgttacaac aaaagaatat aacgaggttt ttaaaaaatg gcaaaaagaa
     7921 aaattggaat ccaatagcaa ataccaaaaa gaactagaaa aatacattaa ataaggaatg
     7981 gtattgatct tgataaaatt tttaaaatac tgtcattttg aatataaagg agtttgatat
     8041 ggagtggatt agattaatag gaatagcaat cattgttgtg ggttttattt taaaatttga
     8101 tacaattgca acagtagtct tagctggttt ggttacagct ttagtttcag gtgtttctct
     8161 cgttgaattt ttggagattt tgggaaaaga atttagcaat cagcgagtgc tcacgatttt
     8221 tatggttacc ttgcctcttg tggggctgtc agaaaccttt ggactcaagc aacgatcaat
     8281 cgatttgatt cgaaagatta aaggtctgac agttggaaac ttctatacag tttatttctt
     8341 tattcgagag ttagctggtt tcttttcaat tcgtctagga ggacaccctc agtttgtcag
     8401 acctttggtt caacctatgg gagaagcagc tgcagagtct caattaggta gaaagttaac
     8461 agaggttgaa gatgagacaa taaaagcgcg tgcggctgcg aatgaaaatt ttggaaattt
     8521 ctttgctcaa aatacgtttg taggtgctgg gggagtcctc ttgatagggg gaacattaga
     8581 tcagttaggc tatgaaagca attatgcagg gattgcttct acatctatta ttgttgctgt
     8641 tataacactt attgtagtgg ggatttacaa ttatttattt gataaaaaat tgatatcaaa
     8701 aaagactagg ggaggagaac aaaaatgaca gagttggcaa agcaactatt agagttgacc
     8761 tatattgtga ttggttgtca atttctccat acagcctatt gtagttataa agataaaaca
     8821 aacccagttc gacttgggac atctgcattt tggactctat tgtctattac gtttataggt
     8881 ggttcctata tgccaaatat gagtattggt attattgtaa tcctattatc gctgttaaca
     8941 ttgtttaagc aagtccgtat cggaaccttg ccatccttag atgaaatgaa agccaatatt
     9001 gaatctaaca ggttgaaaaa taaaattttt attccagtta tgctgatggc aatacttgcg
     9061 ttggtcttag cgcaaatgat tccagaattt agcaagattt cgattagcct tgccgccttg
     9121 tttgctacaa tttctgttct tgtgattacc aatagtcacc ctaagagtct gttatcagaa
     9181 aataatcgaa tgactcagca agtttcaaca agtgggattg ttcctcaatt attaggggct
     9241 ttgggggcta tttttactgt agcaggtgtt ggtgatgtta tctctcatct gattagcggt
     9301 attgttcctt cagatagtcg ctttatagga gttttggctt atgttcttgg aatggttcta
     9361 ttcacaatga ttatgggaaa tgcttttgca gcattcaccg ttattacagc aggtgttgga
     9421 gttccctttg tatttgctct gggagctaat ccaattgtgg ctggtgctct tgccatgaca
     9481 gcaggttatt gtgggacctt attgacccca atggctgcta attttaacgc tctaccagca
     9541 gcattgatgg atatgaaaga tcagaatggc gttataaagg ctcaagcagg tgttgctcta
     9601 gtaatgattg ttattcacat attcttaatg tactttctcg cattttagta aaggaaaata
     9661 aaatgaaaat attggttaca ggttttaatc cttttggagg tgaaaagatt aatccagctt
     9721 tggaggctgt aaaattatta ccatctgaga ttaatggggc tgaagttcgc tgggtagaaa
     9781 ttccaacggt tttttataag tcgtcagaag ttttagaggc agaaatatta cgatatcaac
     9841 cagatgctgt actttgtatt ggacaagcag gcggcaggac cggcttaaca cctgaacgag
     9901 tggctattaa tcaagatgat gctcgcatac ctgataacga aggcaatcaa ccaattgata
     9961 caccgattcg tattgatgga gcatcggcct attttagtag tttacctatc aaagcgatgg
    10021 tacaagctat caaaaaacag ggacttccgg cagttgtatc caatagtgca ggaacctttg
    10081 tttgcaatca tttgatgtac caagctcttt atttagtgga taaaaaattc cctaatatga
    10141 gagcaggttt catgcatatt ccatatatga tggaacaagt agtaaataag ccgaatactg
    10201 caggaatgag tctatgtgat attgtaagag gcatagaggt agctattgaa gctattgtag
    10261 actacaaaga taaggatttg cagttagtag gcggtgagac tcactgataa cctaaaaagg
    10321 atagtcaatt atgcttgttt actaactatt aactatgcta aatcaattga ggttgtttac
    10381 ataaaactct atatcagaga agcctgatat agagtttttt cttgctagtt ttaggatttt
    10441 cttgtaaaat agaaaaagtg aagagaggta tgaaatgagc aagaaagata aaaaaatcga
    10501 aattcaagta gcggatgcca aagttaatgt tggtaaagac agttttgaag gttatacatt
    10561 gactatcggt aaaaaagtta tcggagaaat tgccgaatta gacggacaat ttgccattat
    10621 aaagaatggg aatgtcgata gtttttataa aaaattggaa aaagctgtgg aaattttgat
    10681 tgaaaattat aatttagcaa aataagtctt gtttttttga aattttcatg atataatagt
    10741 ccatgttgat tgtaggagag atagcgaaga ggctaaacgc ggcggactgt aaatccgctc
    10801 cttcgggttc gggggttcga atccctctct ctccatttca ttaatggggt atagccaagc
    10861 ggtaaggcaa gggactttga ctccctcatg cgttggttcg aatccagcta ccccagttct
    10921 taggtaataa tcaagataaa aagcaaaata tcttagggta ttttattttt ataattgaaa
    10981 gacgtgaatg atatgaacat gtccttgcgg gtgcttagga aaaaaattat aagtatgtca
    11041 agtttaagaa aaacttgatt gttggaggat tttttagatg aacgaatttg aagatttgct
    11101 aaatagcgtt agtcaagttg agactggtga tgttgttagt gctgaagtat tgacagttga
    11161 tgcgactcaa gctaacgttg caatctctgg aactggtgtt gaaggtgtct tgactcttcg
    11221 cgaattgaca aacgatcgtg atgcagatat caatgacttt gttaaagtag gagaagtatt
    11281 ggatgttctt gtacttcgtc aagtagttgg taaagatact gatacagtta cataccttgt
    11341 atctaaaaaa cgccttgaag ctcgcaaagc atgggacaaa cttgttggtc gcgaagaaga
    11401 agttgttact gttaaaggaa cgcgtgccgt taaaggtgga ctttcagtag aatttgaagg
    11461 tgttcgtgga tttatcccag cttcaatgtt ggatactcgt ttcgtacgta acgctgagcg
    11521 ttttgtaggt caagaatttg atactaaaat caaagaagtt aacgctaaag aaaaccgctt
    11581 catcctttca cgtcgtgaag ttgttgaagc agctactgca gcagctcgcg ctgaagtatt
    11641 cggtaaattg gctgttggtg atgttgtaac tggtaaagtt gctcgtatca caagcttcgg
    11701 cgctttcatc gaccttggtg gtgttgacgg attggttcac ttgactgaat tgtcacatga
    11761 acgtaacgta tcaccaaaat cagttgtaac tgttggtgaa gaaattgaag tgaaaatcct
    11821 tgatcttaac gaagaagaag gacgtgtatc actttcactt aaagcaacag taccaggacc
    11881 atgggatggc gttgagcaaa aattggctaa aggtgatgta gtagaaggaa cagttaaacg
    11941 tttgactgac ttcggtgcat ttgttgaagt attgccaggt atcgatggac ttgttcacgt
    12001 atcacaaatt tcacacaaac ggattgaaaa tccaaaagaa gctcttaaag ttggtcaaga
    12061 agttcaagtt aaagttcttg aagttaacgc agatgcagaa cgcgtgtcac tttctattaa
    12121 agctcttgaa gaacgtccag cccaagaaga aggacaaaaa gaagaaaaac gtgctgctcg
    12181 tccacgtcgt ccaagacgtc aagaaaagcg tgatttcgaa cttccagaaa cacaaacagg
    12241 attttcaatg gctgatttgt ttggtgatat cgaactttaa tcaaattgaa aattcacaaa
    12301 atcctttgtt tactaaacaa gggatttttc ttttgtctct gctccttttt tgatataata
    12361 gttctatgtt aaaatcagaa aaacaatcac gttatcaaat gttaaatgaa gaattgtcct
    12421 tcctattgga aggcgaaacc aatgttttgg ctaatctttc caacgccagt gctcttataa
    12481 aatcacgttt tcctaatacc gtatttgcag gcttttattt gttcgatgga aaggaattgg
    12541 ttttaggtcc cttccaagga ggtgtttcct gcatccgtat tgcactaggc aagggtgttt
    12601 gtggtgaggc agctcacttt caggaaactg ttattgttgg agatgtgacg acctatctca
    12661 actatatttc ttgtgatagt ctagctaaaa gtgaaattgt ggtgccgatg atgaagaatg
    12721 gtcagttact tggagttctg gatctggatt cttcagagat tgaggattac gatgctatgg
    12781 atcgagatta tttggaacaa tttgtcgcta ttttgcttga aaagacaaca tgggacttta
    12841 cgatgtttga ggaaaaatct taatgtatca agcactttat cgaaaatata gaagtcaaaa
    12901 cttctcccag ttagttggtc aagaagttgt ggctaagact cttaaacaag cggtggagca
    12961 agagaaaata agtcacgctt atcttttttc tggtcctcgt ggaacgggaa aaaccagtgt
    13021 tgctaaaatc tttgccaagg ctatgaactg tcccaatcaa gtgggtggcg aaccttgcaa
    13081 taactgctat atttgtcaag cagtgacgga cggtagttta gaagatgtca ttgaaatgga
    13141 tgcagcttct aataatgggg tagatgaaat tcgcgaaatt cgtgataaat ctacctatgc
    13201 gcctagcctt gctcgttata aggtttatat catagatgag gttcacatgc tgtctacagg
    13261 ggcttttaat gccctcctaa agacgctgga agaaccaaca cagaatgtag tctttatttt
    13321 ggccactact gaattacaca agattcctgc tactattcta tcccgtgtgc aacgttttga
    13381 gtttaaatca attaagacac aggatattaa ggaacatatt cactatatct tagaaaaaga
    13441 aaatatcagt tctgaaccag aggctgtgga aatcattgcc agacgggcgg aaggtggaat
    13501 gcgggacgcc ttgtctattt tggatcaagc cctgagtttg acacagggaa atgagctgac
    13561 gactgctatc tctgaagaaa ttactggcac tattagccta tcagccttgg atgattatgt
    13621 ggcggccttg tctcaacagg atgttcccaa agctttgtct tgcttgaatc ttctttttga
    13681 caatggtaag agcatgactc gttttgtgac cgatcttttg cactatttaa gagacttgtt
    13741 aattgttcaa acagggggag aaaatactca tcatagttca gtctttgtag aaaatttggc
    13801 acttcctcaa aaaaatctgt ttgaaatgat tcgcttagca acagtgagtt tagcagatat
    13861 taagtctagt ttgcagccca agatttatgc tgaaatgatg accgtccgtt tggcggaaat
    13921 caagcccgaa ccagctctat caggagcggt tgaaaatgaa attgctacgc tgagacagga
    13981 agttgcccgt ctcaaacaag agctttctaa tgtaggtgcg gttcctaaac aagttgcacc
    14041 agctcctagt cgaccagcta cgggcaaaac agtctatcgt gtcgatcgca ataaagtgca
    14101 atctatctta caagaggccg tcgaaaatcc tgatttagca cgtcaaaatc taattcgttt
    14161 gcagaatgcc tggggagagg taattgaaag tctaggtggg ccggacaagg ctctgctagt
    14221 tggttctcaa ccggttgctg ccaatgaaca ccatgctatt cttgcttttg agtctaactt
    14281 caatgctggt caaactatga aacgagacaa tctcaatacc atgtttggca atatcctcag
    14341 tcaggcggca ggtttttcac ctgagatttt agctatttcc atggaggaat ggaaagaagt
    14401 tcgcgcagcc ttttcagcca aagccaaatc ttctcaaact gaaaaagaag tagaagaaag
    14461 cctgattcca gaaggatttg aatttttggc tgataaagtg aaggtagagg aagactaaag
    14521 aaagatttcg tgatacaata agtttatgaa taaacaacaa tttattatta tggcgctgtt
    14581 tacagctgct gagacctatt ttttcaatga agcctggatg actggccgct atattatggc
    14641 agccttttgg gcaattttac tctttagaaa tttccgagtc agttatgtga tgggcaaaat
    14701 cgttgatgtc atcgatcagc attttaatag gaaagactag ccctcagctt ccagacaaaa
    14761 tcaaagcctt ttaggctttt ttttgttata ctagaaaagt atatttatag aatttttgct
    14821 ctatttctgg ggaaatcaga cgtttttcta gtaagtactg taaaagtttt gaaaaagaaa
    14881 ggaactatca tgtcagtatt agagatcaaa gatcttcacg ttgagattga aggaaaagaa
    14941 attttaaaag gggttaacct gaccctgaaa acaggagaaa ttgccgctat catgggacca
    15001 aatggtacag gtaaatcgac tctttctgcc gctatcatgg gaaatccaaa ctatgaagta
    15061 actaaaggtg aagttttgtt tgatggcgta aacatccttg agttggaagt ggatgagcgt
    15121 gcgcgtatgg gacttttcct tgctatgcaa tacccatcag aaatccctgg aattaccaat
    15181 gctgagtttc ttcgtgccgc tatgaatgcg ggtaaagaag atgatgagaa gatttcagtt
    15241 cgtgagttta ttactaggct agatgaaaaa atggaattgc tcaacatgaa agaagaaatg
    15301 gcagagcgtt acctcaacga aggcttctct ggtggtgaga aaaaacgcaa tgaaattctt
    15361 caacttttga tgttggagcc aacatttgct cttttggacg agattgactc aggtcttgat
    15421 attgacgctc ttaaagttgt gtctaaaggt gtcaatgcca tgcgtggtga aggttttggt
    15481 gctatgatca tcactcacta ccaacgtctt ttgaactata tcacacctga tgtggtacac
    15541 gtgatgatgg aaggtcgtgt tgtcctttct ggtggtccag aattggctgc gcgtttggaa
    15601 cgtgaaggat acgcaaaatt agctgaagaa cttggctacg actacaagga agaattgtaa
    15661 tttcctcgta tcttttagga gaagtaaatg actagagaaa atattaaact tttttcagaa
    15721 atgcacgctg aaccaagctg gttggctgat ctccgtcaaa aagcttttga caagattgag
    15781 actttggaat taccagttat tgagcgtgtc aaattccacc gttggaatct gggtgatgga
    15841 acgattacag aaaatgagcc atcagcaaat gttccagatt tcacagcttt agatcatcac
    15901 ttgaagttgg tgcaagtagg aactcaaact gttttcgaac aaactccagt tgagttagct
    15961 gaacagggtg ttgtcttcac agactttcac tcagctttag aagaaattcc agagctgatc
    16021 gaagaattct tcatgtcatc tgttaagtat gatgatgaca agttggcggc ttaccacaca
    16081 gcttacttta acagtggtgc tgtactctat attccagata acgtagaaat cacagagcca
    16141 attgaaggaa ttttctacca agatagcgat agcaatgtgc cgtttaacaa gcatattatg
    16201 attatcgctg gtaaaaattc taagattaat tatctggagc gtttagagtc acgcggtgaa
    16261 ggaagtgcca aagcaactgc taatatcaca gtagaagtga ttgcacgttc aggtgcgcaa
    16321 gtcaagtttg ctgctatcga ccgtctaggt gaaaacgtca ctgcctacat tagccgtcgt
    16381 ggtaaattag gcaacgatgc aagtattgac tgggctatcg gtgtcatgaa cgaaggaaat
    16441 gtcgttgctg attttgatag tgacttgatt ggtaatggta gctatgctga cctcaaggtt
    16501 gtagctcttt caagtggtcg tcaggtacaa gggattgata ctcgtgtaac taactatggc
    16561 tgcaactcta tcggaaatat cctacaacat ggggttatcc ttgaaaaagc aactttgact
    16621 ttcaatggta tcggccacat catcaagggt gctaagggag cagatgccca acaagagagc
    16681 cgtgttctca tgctttcaga ccaagcgcgt tcagatgcta acccaattct tttgattgat
    16741 gaaaatgatg tcactgcagg acacgcagcg tctatcggac aagttgatcc agaagacatg
    16801 tattacctca tgagtcgtgg attggataag gcaactgcag agcgtttggt tgttcgtggt
    16861 ttccttggat ctgttatcgt ggagattcca gtcaaggaag ttcgtgatga aatgattgca
    16921 actatcgaag agaaattgtc aaaacgctaa ggggaagcct atgttagatg tagaagcgat
    16981 tcgcaaggat tttccaattt tagatcagat tgtcaatgat gaacctctgg tctatctgga
    17041 caatgctgcg acgacacaaa aaccactagt agttctgaaa gctattaaca gttactatga
    17101 gcaggacaat gccaatgttc accgtggtgt ccatacctta gcggaacgag cgacagcttc
    17161 ttatgaagct gctcgtgaaa ccattcgtaa gtttattaat gcaggctcta caaaggaagt
    17221 tctctttacc agaggaacga caaccagcct taactgggtg gcacgctttg ctgaggaaat
    17281 tctcactgag ggagaccagg tcttgatttc agtaatggaa caccattcta atatcattcc
    17341 atggcaggaa gcttgtcgaa agactggagc agagcttgtc tatgtctatc ttaaagacgg
    17401 tgccttggat atggaggatt tgcgagctaa attgactgat aaggttaaat ttgtttccct
    17461 agctcatgcc tccaatgttc ttggtgtggt caatccgatc aaggaaatca ctcaattagc
    17521 ccaccaagtt ggggcaatca tggtagtgga tggtgctcaa tctacacctc atatgaagat
    17581 tgatgtccag gacttggatc tggacttttt cgccttttcg ggtcacaaga tggctggtcc
    17641 gactggtatc ggtgtccttt acggcaaaga aaagtatctt gagcaaatgt ctccagtaga
    17701 atttggcggc gagatgattg attttgtcta cgagcaatcc gctagttgga aggaattgcc
    17761 ttggaaattt gaggctggaa cgccaaatat ggcaggagct attggacttg cgactgcagt
    17821 tgattatctg gaaaagattg gtatggatgc cgttgaagct catgaacagg aattgattgc
    17881 gtacgtctat ccaaaactgc aggcaattga gggattgacc atttacggtt ctcaggattt
    17941 ggctcaacgt tcgggtgtta ttgcctttaa cctaggtgat ctccatcctc acgatcttgc
    18001 gacggctctg gattatgaag gagtggctgt tcgtgctggt caccattgtg cgcaaccctt
    18061 gcttcagtat ttggaagtcc cagcatcagc tcgtgcaagt ttttatatct ataataccaa
    18121 ggcagattgc gacaaactag tcgatgccct acaaaagaca aaggagtttt tcaatggcac
    18181 tttctaaact agatagcctt tatatggcag tggtagcaga ccattcgaaa aatccacatc
    18241 accaagggaa gttagaagac gctgagcaaa tcagtctcaa caatccgact tgtggggatg
    18301 tcatcaacct ctctgtcaag tttgatgcag aggaccgttt ggaagatatt gcttttctaa
    18361 attcaggatg cacgatttca actgcttctg ctagtatgat gacagatgcc gttttaggaa
    18421 aaaccaaaca agaaatttta gaactggcga ctattttttc tgaaatggtt caagggcaaa
    18481 aagatgagcg tcaagaccaa cttggagacg cggcattctt gtcaggtgtt gccaaattcc
    18541 ctcaaagaat caagtgtgca accctagctt ggaatgccct taagaaaaca attgaaaatc
    18601 aagaaaaaca gtaagacaag tttcttttgt cttatgaatt attagaaatg aagaaaggat
    18661 attatggctg aagaaagagt agaaccaaaa ccaattgacc ttggtgaata taaatttggt
    18721 ttccatgacg atgtagagcc tgtcttatcg acaggaaaag gactcaacga aggtgttatt
    18781 cgtgaattat ctgctgctaa gggtgagcct gagtggatgt tggagttccg tttgaagtct
    18841 tatgaaacct tcaaaaaaat gcccatgcaa acttggggag cagacttgtc agagattgac
    18901 tttgatgact taatctacta ccaaaaacca tctgacaaac cagcccgttc ttgggatgat
    18961 gtacctgaaa agattaaaga aacctttgaa cgtatcggga ttccagaagc tgaacgtgct
    19021 tatttagcag gggcttctgc ccagtacgag tcagaagtgg tttaccacaa catgaaggaa
    19081 gagttccaaa aattaggtat tatctttaca gatacagatt ccgcactcaa ggaataccca
    19141 gacttattta aacaatactt tgcgaagttg gtaccgccga cagataacaa gttggcagcc
    19201 ctcaactcag cagtatggtc gggtggaact tttatctacg tgccaaaagg tgtcaaggta
    19261 gatattccac ttcaaactta tttccgtatc aataacgaaa atataggtca gttcgaacgt
    19321 accttgatta tcgttgatga gggagcaagc gtccactacg tagaaggatg tacagcacca
    19381 acatattcaa gcaatagctt gcacgctgcc attgtagaaa tttttgcttt ggacggagct
    19441 tatatgcgtt atacaactat ccaaaactgg tctgataacg tctataactt ggtaacaaag
    19501 cgtgctaagg ctcaaaagga tgccactgtt gagtggattg atggaaactt gggtgccaaa
    19561 acgactatga aatatccatc tgtttatctt gatggagaag gagcgcgtgg taccatgctc
    19621 tctatcgcct ttgctaatgc agggcaacac caagacacgg gtgctaagat gattcacaat
    19681 gctccacata ccagctcgtc tattgtgtct aaatccatcg ctaaaggtgg aggaaaggtt
    19741 gactaccgtg gacaagtcac ctttaacaag aactctaaga aatctgtttc ccacattgaa
    19801 tgtgatacca ttatcatgga tgacttgtca gcatcagata ctattccatt taatgaaatt
    19861 cacaactcgc aagtggcttt ggaacacgaa gccaaagtat ctaagatttc agaagagcaa
    19921 ttgtattatc tcatgagccg tggattgtca gaatctgagg caactgaaat gattgtcatg
    19981 ggatttgtag aaccctttac aaaagaactt ccaatggaat acgcagttga gctgaaccgc
    20041 ttgattagct atgaaatgga gggatcagtt ggataaaatt tgattttata ctcttcgaaa
    20101 atctcttcaa accacgtcag catcgcctta ccgtatgtat ggttactgac ttcgtcagtt
    20161 tcatctacaa cctcaaaaca gtgttttgag caacctgcgg ctagcttcct agtttattct
    20221 ttgattttga gtattagatt tactcaaaat caaggatttt gaagatgaac ttgtatcaaa
    20281 aaatcgcggt ttaaaatcgc gattttttat aatttctcgt taacaaagcg gacaaactga
    20341 ttccaccaaa cttttaagaa gaaggctttt tcaattttct tgtctgctac catttcgaaa
    20401 ctagggcgct ctgtggtgat gtaaccttga ccaatcaagt ccttgtcttc ataagtcaaa
    20461 tggccaacca ctgttccagc ttcaagtggt gctgggattg ctttggaatc aggtgtgaat
    20521 tgaacagatt gggaagattg attcccaaca cgttcgatta gatagatatc ctctggagcc
    20581 actgcagtta ctgtatcttc ttttccatct tgtacagggg ctttgctatc ttgataggca
    20641 tcgccttgtt gaacgatttt gcgaagtgta aatgtagaag aaatataatc cattagggaa
    20701 gatgtagctg taaatcgagc gtaaggatta ttgtcttgat gatctgcatt taaaacaact
    20761 gtgatgactc tcatgccttt ttcgacagta gtaccaacaa aagactctcc agccttatct
    20821 gttgttcctg tttttagccc atcaaaacca ccacggtaag caggcatacc ttctaacatg
    20881 tagttggttg aagtgattgt catcccagca aaagtagaag aaggtttttt ggtgatttct
    20941 aagacttgtg ggtatttttt gatgaggttg cgagcaacga tagcgacatc ataagcacta
    21001 agcttatttt cctcatcttt tttagaacct gggtaaatgt tatcccctag agtttcattg
    21061 ttaagacctg tcgtattgac aacagtggca tcctgaattc cccattccaa gagttttgcc
    21121 cgcatcatat cgatgaaatc tttttctgag ccagcaattt tctcagctag ggcaatagcg
    21181 gcgctgttgg cactagatac cagagttgct tcaagcaact cttcgacagt ataattacgg
    21241 gcctccatag gaatattact ggcttcagaa tttgtcgtca attgataagg ataatcagaa
    21301 atatctacag gagtggagag ggtaatactt ccgttttcca aagcttcata gaccagataa
    21361 gcagtaatca attttgttat ggaagcaatt tcgacaggtt gcgttgcatc cttctcatag
    21421 agaattttac cagtatttgc ctcaacagca atcgcatgtt tagcggcaat ggtaaaatct
    21481 tgagcaacag cagtagaagc accccctaaa agagagacag ttaacaaagt taaaaatatt
    21541 tttttcatag tagtcttatt ctatcataaa gaaaaaaaat attcttgctt taataattca
    21601 tctgttaagc tttttgaaaa tatggtaaaa taaagtgagg gaggtaactc atgtttcgta
    21661 gaaataaatt atttttttgg accacagaaa ttttactctt aaccatcatc ttttacctat
    21721 ggagacagat ggggtctttg attaaccctt ttgttagcgt gcttaataca attatgattc
    21781 catttttatt agggggcttt ctttattatt tgacaaaccc tattgttact ttcttaaata
    21841 aagtctgtaa actcaatcgt ttgcttggta ttttaattac cttgtgtact ttggtctggg
    21901 gaatggtcat aggtgttgtc tatctcttac ctattttgat taatcagtta tctagtttga
    21961 ttatatctag tcaaactatt tatagtcgag tacaagactt aatcatagac ttatctaatt
    22021 atcctgcgct ccagaatttg gatgtagaag ctacaattca gcagttaaac ttatcctatg
    22081 ttgatattct tcaaaatatc ctaaatagcg tatcaaatag tgtggggagc gtcttgtcag
    22141 ctcttatcag tactgttttg attttgatta tgactccagt ttttttggtt tatttcttat
    22201 tagatggaca taaattcttg cccatgcttg aaagaacgat tctaaagagg gatcgcttgc
    22261 atattgcagg cttattaaag aatttaaatg cgacgattgc tcgctatatt agtggagttt
    22321 cgattgacgc aatcattata ggttgtttgg cttatattgg ctatagtatt attggtttaa
    22381 aatatgcttt agtttttgcc attttttctg gtgtagccaa tttaattcct tatgtggggc
    22441 caagtattgg tttgattcct atgatcatcg caaatatatt cactgatccc catagactgc
    22501 tgattgcagt gatttatatg cttgttgttc agcaggtaga tggcaatatc ttatatcctc
    22561 gaatcgtagg aagtgttatg aaggttcatc caatcacgat tttagtttta cttttgttgt
    22621 caagcaatat ctatggtgta gttggaatga ttgtcgcagt gccaacctat tctatcttga
    22681 aagaaatttc taagttctta tcccgtttgt atgaaaatca taaaataatg aaagaacgag
    22741 aaagagaatt agctaagtaa aagtcaggag aaccctgatt tttctttact ggaagtggcc
    22801 tttagattag aagactgaaa ataagttaaa gtcttaaact aattttcaca gctaagaata
    22861 gtagaagtta atctgataaa aatcgaaaaa accagtggaa ttctgtgtca gggtaagttc
    22921 cactggtttt catagtctat taaagttcga atgaaaccta tttatagtag attgaaacta
    22981 gaatagtaca cctctaattc taaaacattg ttagaaatcg atttgactgt cctgatctat
    23041 tcgttctatt cttatttcat tttactatat tttggtgcaa taagtgaaaa gtagtccgaa
    23101 taatataagg attgatttta tagtttttaa actcaaatga attgaaataa agagagtacg
    23161 aaaattctca tctgaaagta ttttagaata attctcttcg tgaatttctt caaaacagat
    23221 agcttcatct taggtatgtg atttcttttt gcatttttga gttagataag gtataatggt
    23281 tttattgtct tttggggtcg ttacggattc gacaggcatt atgaggcata ttttgcgact
    23341 cgtgtggcga cgtaaacgct cagttaaata taactgcaaa aaataacact tcttacgctc
    23401 tagctgccta aaaaccagca ggcgtgaccc gatttggatt gctcgtgttc aatgacaggt
    23461 cttattatta gcgagatacg attaagcctt gtctagcggt ttgataagag attgatagac
    23521 tcgcagtttc tagacttgag ttatgtgtcg aggggctgtt aaaataatac ataacctatg
    23581 gttgtagaca aatatgttgg caggtgtttg gacgtgggtt cgactcccac cggctccatt
    23641 attcctttgc attcttttgc attccttggt aaaacgttgt taaatcaacg ttttttattt
    23701 ttatctttgg tattcctttg cattcttttg ctaaaaaggg agtcacaaac agaccctatt
    23761 ttaaaaaaag gatagaaaaa aggatacaac atttgtcgca tcctaaaaat aatctttttt
    23821 ccacggaaga catgggattc gaacccacgc acgctattac acgcctaccg cgtttccaac
    23881 acggcctctt aagcctcttg agtaatcttc caatacttac tcaaatagtc taccataaag
    23941 gctcttatct tgcaataaaa attctagaaa taagaaaaat gatagatttt gaaagaaaat
    24001 gataaaaaat gcttgacttc aaaagaaagt atgatagaat gaatagtgta aacgataaca
    24061 ggaggtgatt cggtgttaaa aacagagcgg aagcaactga ttttagagga gttaaatcaa
    24121 catcatgtag tttctctaga aaaattagtt agtttgctag aaacgtcaga atcaacggtt
    24181 cgaagagact tggatgagtt ggaagcggaa aacaagcttc gtcgtgtgca tggtggagca
    24241 gaactccccc actccttaca ggaagaagaa accattcaag aaaaatctgt caaaaacctt
    24301 caagaaaaga agttgctggc tcagaaagca gcctctctca ttaaagaaaa agatgtcatc
    24361 tttatcgatg ctggaacaac aactgctttt ttgattcatg aattggtcaa taagaatatt
    24421 acagttgtga ccaactccat tcaccatgcc gctcagttgg ttgaaaagca gattccaact
    24481 gtcatggttg gaggaaacgt caagacggcg acagatgcta gtatcggtgg cgttgctctt
    24541 aaccagatta accaattgca ctttgaccgt gcctttatcg gaatgaatgg tgttgacgat
    24601 ggctattata cgactcctga tatggaggag ggagctgtga aaagagctat tttggagaat
    24661 gccaagcaga cctacgtctt ggtggattcg tcaaaaattg gacaaacttg ctttgccaag
    24721 gtagcaccac tcaaacgcgc tatcgttatc actagtcaag ggcatgagct cttgcaggtt
    24781 attaaggaga aaacggaggt aatagaagta tgatttatac agtcacactc aatccatcca
    24841 ttgactatat cgttcgtttg gaccaagtca aagttggtag tgtaaatcgt atggacagtg
    24901 atgataagtt tgctggtggg aaaggaatca atgtcagccg tgtcttgaaa cgtttgaata
    24961 taccaaatac agcgacggga tttatcggtg gctttactgg taaatttatc acagatactt
    25021 tagcagagga agaaatcgag acacgttttg tccaggtggc agaagatact cgtatcaatg
    25081 ttaaaatcaa agcagaccaa gaaacagaaa tcaacggaac gggtccaact gttgaatcgg
    25141 ttcagctaga agaattgaaa gctattttat ctagtctgac agcagaagat acagttgtct
    25201 ttgcaggttc aagtgctaaa aatctaggca atgttatcta taaggatttg atttccttga
    25261 cgcgccagac tggtgcgcaa gtggtctgtg actttgaagg acagacctta attgatagtt
    25321 tggactacca gcctcttctt gtaaaaccaa acaatcatga acttggagcg atttttgggg
    25381 ttaaactcga aagtttagat gaaattgaga aatacgctcg tgagttactg gctaagggtg
    25441 ctcaaaatgt tattatctct atggctggtg atggtgccct tcttgtcaca tctgagggag
    25501 cttacttcgc taaaccaatc aaaggaacag tcaaaaattc agttggagct ggtgattcta
    25561 tggttgctgg attcacaggt gaatttgtca aatcaaaaga cgtagtagaa gccttcaaat
    25621 ggggagtggc ttgcggaacg gcaactacct tctcagatga cttggcaacg gcggaattta
    25681 ttaaagaaac atatggaaaa gttgaggtag aaaaacgatg aaaattcaag acctattgag
    25741 aaaagatgtc atgttgctag atttgcaggc aactgaaaaa acagctgtca tcgacgagat
    25801 gattaaaaat ttgacagacc acggttatgt aacagatttt gaaacattta aagaaggaat
    25861 tttggcgcgt gaagctttga cttctactgg tttgggtgat ggaatcgcaa tgcctcacag
    25921 caaaaacgct gctgtcaaag aagcgacagt tctatttgct aagtcaaata agggtgttga
    25981 ctacgagagc ttggatggac aagcaactga cctcttcttc atgattgcag ctccagaagg
    26041 tgccaatgat actcacttgg cagccttggc agaattgtct caatacttga tgaaagacgg
    26101 ttttgcagac aaacttcgtc aagcaacatc tgcagaccaa gttatcgaac tttttgacca
    26161 agcttcagaa aaaactgagg aacttgttca agcacctgct aatgactctg gtgactttat
    26221 cgtagctgtt acagcttgta caacaggtat tgcccacact tacatggccc aagaagccct
    26281 tcaaaaagta gctgctgaaa tgggggttgg tatcaaggtc gaaaccaacg gtgctagcgg
    26341 tgttggaaat caactaactg cagaagatat ccgtaaggct aaagctatta tcattgcagc
    26401 agacaaggcc gttgaaatgg atcgatttga tggaaaacca ttgatcaatc gtccagttgc
    26461 tgacggtatc cgtaagacag aagagctaat taacttggct ctttcaggag atactgaagt
    26521 ctaccgtgcc gctaatggtg ccaaagctgc aacagcctct aacgaaaaac aaagccttgg
    26581 tggtgccttg tacaaacact tgatgagtgg tgtatctcaa atgttaccat tcgttatcgg
    26641 tggtggtatc atgattgccc ttgccttctt gattgacggt gctttgggtg ttccaaatga
    26701 aaaccttggc aatcttggtt cttaccatga gttagcttct atgttcatga aaattggtgg
    26761 agctgccttt ggtttgatgc ttccagtctt tgcgggttat gttgcctact ctattgctga
    26821 aaaaccgggt ttggtagcag gtttcgtggc tggtgctatt gccaaagaag gttttgcctt
    26881 tggtaaaatt ccttatgccg caggtggtga agcaacttca actcttgcag gtgtctcatc
    26941 tggtttccta ggtgcccttg ttggtggatt tatcgcaggt gccttggttc ttgccatcaa
    27001 gaaatacgtt aaagttcctc gttcactcga aggtgctaaa tcaatccttc tattgccact
    27061 tcttggaaca atcttgacag gatttgttat gctagctgtg aatatcccaa tggctgcaat
    27121 caacactgct atgaatgact tcctaggcgg tcttggagga ggttcagctg tccttcttgg
    27181 tatcgtcctt ggtggaatga tggctgttga catgggtgga ccagttaata aagcagctta
    27241 tgtctttggt acaggtacgc ttgcagcaac tgtttcttca ggtggttctg tagccatggc
    27301 agcagttatg gctggaggaa tggtgccacc acttgcaatc tttgtcgcaa ctcttctttt
    27361 caaagataaa tttactaagg aagaacgtaa ctctggtttg acaaacatca tcatgggctt
    27421 gtcatttatc actgagggag cgattccatt tggtgccgct gacccagctc gtgcgattcc
    27481 aagcttcatc cttggttcag cagtagcagg tggactcgtt ggtcttactg gtatcaaact
    27541 catggcgcca cacggaggaa tcttcgttat cgcccttact tcaaatgctc tcctttacct
    27601 cgtttctgtc ttggtaggag caatcgtaag tggtgtggtt tatggttacc tacgcaaacc
    27661 acaagcataa aaaatagaaa aatgaaaaga ttggaccgtt tggtgcagtc tttttctctt
    27721 cccgaaatgc ctgtgaaata tggtataata gaagaatggc aaacaagaat acaagtacaa
    27781 caagacggag accgtctaaa gcagaactgg aaagaaaaga agcgattcaa cgaatgttga
    27841 tttcgttagg aattgcgatt ttattgattt tcgcagcctt caaattaggg gctgcaggta
    27901 taacccttta taatttaatt cgcttgctag tgggtagcct agcttatctg gcgatattcg
    27961 gcctattaat ctatctcttc tttttcaagt ggatacgaaa acaggaagga ctcttatctg
    28021 gctttttcac catatttgct ggcttactct tgatttttga ggcctacttg gtttggaaat
    28081 atggtttgga caagtccgtt ctaaaaggga ccatggctca ggttgtgaca gatctgactg
    28141 gttttcgaac gactagcttt gctggagggg gcttgatcgg ggtcgctctt tatattccaa
    28201 cagcctttct cttttcaaat atcggaactt actttattgg ttctatcttg attttagtgg
    28261 gttctctcct agtcagccct tggtctgttt acgatattgc tgaatttttc agtagaggct
    28321 ttgccaaatg gtgggaaggg cacgagcgtc gaaaagagga acgctttgtc aaacaagaag
    28381 aaaaagctcg ccaaaaggct gagaaagagg ctagattaga acaagaagag actgaaaaag
    28441 ccttactcga tttgcctcct gttgatatgg aaacgggtga aattctgaca gaggaagctg
    28501 ttcaaaatct tccacctatt ccagaagaaa agtgggtgga accagaaatc atcctgcctc
    28561 aagctgaact taaattccct gaacaggaag atgactcaga tgacgaagat gttcaggtcg
    28621 atttttcagc caaagaagcc cttgaataca aacttccaag cttacaactc tttgcaccag
    28681 ataaaccaaa agatcagtct aaagagaaga aaattgtcag agaaaatatc aaaatcttag
    28741 aagcaacctt tgctagcttt ggtattaagg taacagttga acgggccgaa attgggccat
    28801 cagtgaccaa gtatgaagtc aagccggctg ttggtgtaag ggtcaaccgc atttccaatc
    28861 tatcagatga cctcgctcta gccttggctg ccaaagatgt ccggattgaa gcaccaatcc
    28921 ctgggaaatc cctaatcgga attgaagtgc ccaactccga tattgccact gtatctttcc
    28981 gagaactatg ggaacaatcg caaacgaaag cagaaaattt cttggaaatt cctttaggga
    29041 aggctgttaa tggaaccgca agagcttttg acctttctaa aatgccccac ttgctagttg
    29101 caggttcaac gggttcaggg aagtcagtag cagttaacgg cattattgct agcattctca
    29161 tgaaggcgag accagatcaa gttaaattta tgatggtcga tcccaagatg gttgagttat
    29221 ctgtttacaa tgatattccc cacctcttga ttccagtcgt gaccaatcca cgcaaagcca
    29281 gcaaggctct gcaaaaggtt gtggatgaaa tggaaaaccg ttatgaactc tttgccaagg
    29341 tgggagttcg gaatattgca ggttttaatg ccaaggtaga agagttcaat tcccagtctg
    29401 agtacaagca aattccgcta ccattcattg tcgtgattgt ggatgagttg gctgacctca
    29461 tgatggtggc cagcaaggaa gtggaagatg ctatcatccg tcttgggcag aaggcgcgtg
    29521 ctgcaggtat ccacatgatt cttgcaactc agcgtccatc tgttgatgtc atctctggtt
    29581 tgattaaggc caatgttcca tctcgtgtag catttgcggt ttcatcagga acagactccc
    29641 gtacgatttt ggatgaaaat ggagcagaaa aacttcttgg tcgaggagac atgctcttta
    29701 aaccgattga tgaaaatcat ccagttcgtc tccaaggctc ctttatctcg gatgacgatg
    29761 ttgagcgcat tgtgaacttc atcaagactc aggcagatgc agactacgat gagagttttg
    29821 atccaggtga ggtttctgaa aatgaaggag aattttcgga tggagatgct ggtggtgatc
    29881 cgctttttga agaagctaag tctttggtta tcgaaacaca gaaagccagt gcgtctatga
    29941 ttcagcgtcg tttatcagtt ggatttaacc gtgcgacccg tctcatggaa gaactggaga
    30001 tagcaggtgt catcggtcca gctgaaggta ccaaacctcg aaaagtgtta caacaataaa
    30061 aaaatagctt ctttccaagt ttggagggaa gctattttag tggctattga ttgcttttat
    30121 tttctgaagt tggcgcattg gactgttttt cgttttcagt agcaggttta cttgaagcag
    30181 gagtagaaga gtcctgagtt gctgttttct gatcttcttt tttctcttcc ttgacgctag
    30241 attttggtgt ttcctcttgc tgtgtttttt cttgactagt gttagtctct ttagttggac
    30301 tggtgttttc cttaggggat tccttttgga tttctttgac aatggttgtc gtctggcttg
    30361 tcgtaggttc ttttttaata tttttgttat tatccaaggc gttcataatc gtgatacttg
    30421 cggtaatcaa gccaaggata ctagcgattg tagcaacggt tttttgaaag actgtaaagc
    30481 cttttttgat gtgttctgtt tttggttttg aagttctacg atagttagac atacattctc
    30541 tcctttgatt atgatttatt atactctgtt tctttaaaaa aatcttaaaa aaagagaaat
    30601 ttccctttct tgtcgcaagc tccgtttcat gatacaatag aggaagtgat tttagaaagc
    30661 gtgagaaaca tgatttactt tgataattca gcgacgacca agccttatcc tgaagccctt
    30721 gaaacctata tgcaggtcgc ttcaaaaatt ttaggaaacc catctagtct ccatcgtttg
    30781 ggagaccaag caacacgaat cttagatgct tctcgccaac agattgcaga tttaatcggt
    30841 aagaaaagcg atgaaatctt ctttacctcg ggtggaacag aaggggataa ctggcttatc
    30901 aagggtgtgg cctttgaaaa agctcagttt ggcaagcaca tcattgtttc agccattgaa
    30961 catccagcag tcaaagagtc agccctctgg ttgaaaagtc aaggatttga agtggatttt
    31021 gctccagttg ataagaaagg cttggtcgat gttgaggcgt tagcaggttt gatacggcat
    31081 gatacaatcc tcgtttccat catggctgtg aacaatgaaa tcggctctat ccaacctatt
    31141 gaggctattt cagaattctt ggcagacaag ccgactattt ccttccacgt tgatgcggtt
    31201 caggcgcttg ccaaaattcc gactgaaaag tatctgacag aacgggtgga ttgcgcgact
    31261 ttctctagtc acaagttcca cggggttcga ggtgttggct ttgtctatat caaatctggc
    31321 aagaagatta cacctcttct tacaggtggt ggccaggagc gagattatcg ttcgacaact
    31381 gaaaatgtgg cagggattgc agcgacagcc aaggccctcc gtttgtctat ggaaaagcta
    31441 gatatcttta ggagcaagac tgggcagatg aaggcagtga ttcgccaagc tcttctgaac
    31501 tatccggata tttttgtctt ttcagatgag gaaaactttg cacctcatat tctgactttt
    31561 ggaatcaaag gtgttcgagg tgaagtcatc gttcacgcct ttgaagacta tgatattttc
    31621 atctcaacaa cctcagcttg ttcatctaag gcaggaaaac cagccggtac cttgattgcc
    31681 atgggagtgg acaaagataa ggccaagtca gctgtgcgtc ttagcctaga cttggaaaat
    31741 gatatgagtc aggtcgagca gtttttgacc aagttaaaat tgatttacaa tcaaactaga
    31801 aaagtaagat aggagcattc atgcagtatt cagaaattat gattcgctac ggagagttgt
    31861 caaccaaggg taaaaaccgt atgcgtttca tcaataaact tcgtaataat atttcggacg
    31921 ttttgtctat ctatacccaa gttaaggtaa cagcagatcg cgaccgtgcc cacgcttacc
    31981 tcaatggagc tgattacaca gcagttgcag aatctctcaa acaagttttt ggaattcaaa
    32041 acttttctcc tgtttataag gttgaaaaat ctgtagaagt tttgaagtct tctgtccaag
    32101 agattatgcg ggacatctac aaggaaggta tgacctttaa gatttctagc aagcgtagcg
    32161 accacaactt tgaacttgat agtcgtgaac tcaaccaaac acttggaggg gctgtattcg
    32221 aagccattcc aaatgtgcaa gttcaaatga aaagtcctga catcaatctt caggtggaga
    32281 ttcgtgaaga agcagcctat ctttcttatg aaaccattcg tggggctggt ggtttgccag
    32341 ttggaacttc aggtaaaggg atgctcatgt tgtcaggagg gattgactca cctgtagcag
    32401 gttatcttgc tcttaagcgt ggggtggata tcgaggcagt tcactttgct agtccaccat
    32461 atactagtcc tggtgccctc aagaaagcgc aggacttgac ccgtaaattg accaagtttg
    32521 gcggaaatat ccagtttata gaggtgcctt tcacagagat tcaagaggaa atcaaagcca
    32581 aagcgccaga agcttatttg atgactctaa ctcgtcgctt tatgatgcgg attactgacc
    32641 gtattcgtga ggtacgaaat ggtttggtta tcatcaatgg ggaaagtcta ggtcaagtag
    32701 ccagccaaac ccttgaaagt atgaaggcta tcaatgctgt taccaacact cccatcattc
    32761 gtcctgtggt taccatggac aagttggaaa tcattgacat cgcccaggaa atcgatacct
    32821 ttgacatttc aatccaaccg tttgaagact gttgtaccat ttttgcacca gatcgtccaa
    32881 aaacaaatcc taaaattaag aatgcggagc agtacgaagc gcgtatggat gttgaaggct
    32941 tggttgagcg agcagtggct ggaatcatga ttactgaaat cacacctcaa gccgaaaaag
    33001 atgaagttga tgacttgatt gacaatctgc tctaattcag aaaatccaaa agaatagcga
    33061 aaatcagtaa aaaaagttag ttttttctct aaaaacaggt aaaaaactaa ctttttttat
    33121 ttttatgata taatgatata aaattttgaa tatagagagt tttctgacaa tgaatcaatc
    33181 ctacttttat ctaaaaatga aagaacacaa actcaaggtt ccttatacag gtaaggagcg
    33241 ccgtgtacgt attcttcttc ctaaagatta tgagaaagat acagaccgtt cctatcctgt
    33301 tgtatacttt catgacgggc aaaatgtttt taatagcaaa gagtctttca ttggacattc
    33361 atggaagatt atcccagcta tcaaacgaaa tccggatatc agtcgcatga ttgtcgttgc
    33421 tattgacaat gatggtatgg ggcggatgaa tgagtatgcg gcttggaagt tccaagaatc
    33481 tcctatccca gggcagcagt ttggtggtaa gggtgtggag tatgctgagt ttgtcatgga
    33541 ggtggtcaag ccttttatcg atgagaccta tcgtacaaaa gcagactgcc agcatacggc
    33601 tatgattggt tcctcactag gaggcaatat tacccagttt atcggtttgg aataccaaga
    33661 ccaaattggt tgcttgggcg ttttttcatc tgcaaactgg ctccaccaag aagcctttaa
    33721 ccgctatttc gagtgccaga aactatcgcc tgaccagcgc atcttcatct atgtaggaac
    33781 agaagaagca gatgatacag acaagacctt gatggatggc aatatcaaac aagcctatat
    33841 cgactcgtcg ctttgctatt accatgattt gatagcaggg ggagtacatc tggataatct
    33901 tgtgctaaaa gttcagtctg gtgccatcca tagtgaaatc ccttggtcag aaaatctacc
    33961 agattgtctg agattttttg cagaaaaatg gtaagttaag aaaggaaaaa acgaaatgca
    34021 tattgaacat cttagccact ggagtggtca tcttaaccgt gaaatgtacc ttaaccgtta
    34081 tggacatggt gggattccag ttgtggtctt tgcttcatca ggtggtagtc acaacgaata
    34141 ctatgatttt ggcatgattg atgcctgtgc ttcctttatc gaggaaggcc ttgtccagtt
    34201 ctttacccta tctagtttgg atagtgagag ctggttggct acttggaaaa atgctcatga
    34261 ccaagcggaa atgcaccgtg cctacgaacg ttatgtgatt gaggaggcca ttcttttatc
    34321 aagcacaaga caggttggtt tgatggcatg atgacgacag gttgctctat gggagcctat
    34381 catgcactca atttcttcct ccagcatcca gatgtcttta ccaaagtgat tgctctcagt
    34441 ggtgtttacg acgcacgttt ctttgtcggt gattactaca acgatgatgc tatttaccaa
    34501 aactcgccag tagattatat ttggaaccaa aacgacggct ggtttattga ccgttaccgt
    34561 caggcagaga ttgtgctgtg tacggggctt ggagcctggg aacaagatgg tttgccatcc
    34621 ttttacaagc tcaaagaagc ctttgacaag aaacaaattc cagcctggtt tgctgaatgg
    34681 ggacatgatg tcgcccatga ctgggaatgg tggcgtaaac aaatgcctta tttcctcggt
    34741 aatctctatt tataaaagga gttacctatg aattaccttg ttatttctcc ctactatcca
    34801 caaaactttc aacagtttac catcgaacta gctaataaag gcatcacagt cttgggaatt
    34861 ggtcaagagt cttacgagca attggatgag cccttgcgca atagcttgac cgagtatttt
    34921 cgtgttgata atcttgagaa catagatgaa gtcaaacgtg cagttgcttt tctcttttat
    34981 aaacatggtc caattggccg catcgagtct cacaatgaat actggcttga gctagacgca
    35041 acactcagag aacaattcaa tgtttttggt gccaaaccag aggatctcaa aaagacgaaa
    35101 tataagtctg aaatgaagaa acttttcaaa aaagcaggtg ttcctgtggt acctggagct
    35161 gttatcaaga cggaagcaga tgttgatcaa gcagtgaaag aaatcggtct tccaatgatt
    35221 gccaaacctg ataatggagt gggagcagcc gcaaccttta aacttgagac agaagacgat
    35281 atcaatcact tcaagcaaga atgggaccat tcaacccttt atttctttga aaaatttgtc
    35341 acttccagcg aaatctgtac ctttgacggg ctcgtggaca aggatggaaa gattgtcttc
    35401 tcaacaacct ttgactacgc ctatacaccg cttgacctca tgatttataa gatggacaat
    35461 tcttattatg tgctcaagga tatggatcct aaactgcgca agtatgggga agcaattgtc
    35521 aaagaatttg gtatgaaaga acggtttttc catattgagt tcttccgtga gggggacgat
    35581 tatattacca tcgagtacaa taaccgccct gcaggtggtt ttaccattga tgtttataac
    35641 tttgctcatt ccttggacct ttatcgtggc tatgcagcta ttgtcgcagg agaggagttc
    35701 ccggcgtcag actttgaaac tcagtattgt ttggctactt ctcgccgtgc aaatgctcac
    35761 tatgtttatt cagaagagga tttgcttgcc aaatatagcc agcagttcaa ggttaaaaaa
    35821 gtcatgccag ctgccttcgc ggaacttcaa ggagattacc tgtatatgct gaccactccg
    35881 agtcgacaag aaatggagca gatgattgca gatttcggac aacgtcaaga ataagaacta
    35941 tcggattaag gaaattaact cccttaatcc ttttgttttg tctgataaaa aataagagca
    36001 tcccaacaag gtagctatca taaaacttgt tcgataacta tttgaagcag gattaggtgg
    36061 tcagaaatta aattttaata tttcaattga gtcatagtat tgtgtttgcg tatccttaaa
    36121 tcagctaaaa ggatccatga cgacacctat acgatatagt tttcaagata ccaaacaagt
    36181 ctattaatat tcaatgaaaa tcaaagagca aactaggaag ctagccgcag gtttctcaaa
    36241 acactgtttt gaggttgtgg atagaactga cagagtcagt atcatatacc tacggcaagg
    36301 tgaagctgac gtggtttgaa gagattttcg aagagtataa aatattcagg tgacgcatag
    36361 atatagttaa ttgaagcttt gtttgaaatc tgataaaata atgatattac taagttttaa
    36421 aaactaaaga aaagggaaga tatgattaca ggcgaattaa aaaataaaat cgatcagctg
    36481 tgggaaattc tttggacaga aggaaacgca aatcctttaa caaatattga acagttgact
    36541 tatctcttat ttatgaaaga tttggatagt gtcgagcttg gacgtgaaag tgatgctgaa
    36601 tttctaggga ttccttatga gggagttttt ccaaaagata aacctgaata ccgttggtca
    36661 acttttaaaa atataggaga tgctcaggaa gtttatcgtt taatgactca ggagattttt
    36721 ccgtttatta aaaatctcaa gggggataca gatgatacag ccttttcacg atatatgcga
    36781 gaagctattt ttcaaataaa taaacctgct acgcttcaaa aggcaatttc tatcttagat
    36841 gtttttccaa ctaggggatt agatgtagat tttgataatg acaaacaaag tattactgat
    36901 atcggagata tctatgaata tctgttatca aaattgtcga ccgcaggtaa aaatggacag
    36961 ttccgtacac ctcgtcacat catcgatatg atggttgagt tgatgcaacc gactatcaaa
    37021 gatatcatct cagatcccgc tatgggttct gctggcttct tagtatctgc tagccgttac
    37081 ttaaagcgta agaaagatga atgggaaacc aatacagata atatcaatca ttttcataat
    37141 cagatgtttc atggaaatga tacggatacg actatgttga gacttggggc gatgaacatg
    37201 atgctacatg gagtagaaaa tccacaaatc agttaccttg actcgctgtc tcaagataat
    37261 gaagaagccg ataaatatac tttggtttta gcaaatcctc cttttaaggg ctcacttgac
    37321 tacaattcaa cctctaatga ccttcttgca accgtaaaaa ccaaaaaaac agaattactc
    37381 tttctttctc ttttcttgcg aactttaaaa ccaggtggac gagcagcagt tatcgtacct
    37441 gatggtgtcc tttttggttc gtctaaagct cataaaggaa ttcgtcagga aattgtagag
    37501 aatcataagc ttgatgctgt aatctcaatg cctagtggtg tgttcaagcc ttatgctgga
    37561 gtttcaactg ccattctcat ctttacaaaa actggtaatg gtggtactga caaagtctgg
    37621 ttttacgata tgaaagcgga tggtttaagt ttggatgata agcgacaacc gattagcgac
    37681 aatgatattc cagatattat cgaacgcttt catcatcttg aaaaagaagc agaacgtcag
    37741 agaacggatc aatctttctt tgttccagtt gctgagataa aggaaaatga ttatgatttg
    37801 tctatcaata aatataaaga gattgagtat gaaaaagttg agtatgaacc aacagaggtc
    37861 atcttaaaga aaatcaatga tttagaaaaa gaaattcaag ctggcttggc tgaattagaa
    37921 aaattactca agtagagagg tggctgtatg aaaaaagtga agttggggga agtcttatct
    37981 ctaaaaaaag gcaagaaagc cactgtactt gctgaacaaa caactctaag ccaacgttat
    38041 attcaaatag atgatttaag aaataataat aatttaaaat tcactgaaag tttaaatatg
    38101 actgaagcac tcccagatga tattctgata gcatgggatg gagctaatgc aggaacagtt
    38161 ggttatggat tatcgggagc tgttggtagt acaattacgg tcttaaaaaa gaatgagcga
    38221 tacaaagaaa aaattatatc agattacttg ggagtctttt tggaaagtaa atcgcagtat
    38281 ttacgagaac attcaacagg tgcaacaatt cctcatttaa acaagaatat attacttgat
    38341 ttacaattag aattgctagg tatcgaagaa caagagaaca ttatctgtat tcttaatacg
    38401 attaaaaggc ttattactaa aagaaaattg cagttagatg aactaaactt gctcgtcaaa
    38461 tcccgattta acgagatgtt tggggatgtt attctaaatg aaaaagaatg gaaagttagc
    38521 aaatggaacg agattctaac aataagaaat ggtaaaaatc aaaaacaggt tgaagatgct
    38581 gatgggaaat ttcctattta tggaagtggg ggaattatgg gatatgctaa agattggata
    38641 gtgaagaaaa attcagttat tattggacgt aaaggaaata taaataaacc tattttagtt
    38701 agagaaaatt tttggaatgt agatacagca tttggattag agcctgtttt agaaaaaata
    38761 aactcagaat atttattcta tttttgtcaa ttatacaatt ttgagaagtt aaataaggct
    38821 gtaacaatac ctagtttaac taaatcagat ttattaaata tttccatccc cctcccccca
    38881 ctagccctcc aaaatgagtt cgcagacttt gtagccctgg tcgacaaatc acaatttgct
    38941 tgtgagatag ctataaaagt gtggagaaat agcttgaaat ttagtataat atagctaaac
    39001 tatttgttta aagtgagaaa aaaatgggaa attttagctt tcttttaaaa aatgacgaat
    39061 atgaatcttt ttcaaaacct tgcattgaag ctgagaatat gattgctaca tcaactgtgg
    39121 ctactgcctt tatggcgcgt cgtgctttag agcaggctgt ccattggata tatagtcacg
    39181 attcatattt agaagctccc tatcgtgcta ctctatcttc tttagtatgg gatgatgatt
    39241 ttagggatat cgtagattct gaactccaca agcagatagt tctgttgatt cggtggggaa
    39301 accatgctgc tcatggtggt gaaattaagg aacgagaagc gattttagct ttgcatcatt
    39361 tgtatcagtt tgttaatttt atcgattatt gttacagcaa tgagtttgtg gagcgttatt
    39421 ttgatgagaa gtgcttacca ctttcagcaa acatcaaata ccgagaaact ccacaatcta
    39481 tgataaagtt acaagacagt ttaccagaac tgcctgattt tcatgaacag atggctgctc
    39541 agtccgtaga agttcaagag acttatactg aaaaacgtga gactgcagcg caacggcaag
    39601 atgtgccttt ccatattgat caattatctg aggcagagac aagaaagctc tttattgata
    39661 tcgatctccg tttagcagga tggatatttg aagaaaactg tcgtgttgag atagccgttg
    39721 atggtctcaa gcacggttca ggaattggtt actgtgacta tgtactttat ggtaaaaatg
    39781 ggaaaatttt agcgattgtg gaggctaaaa aagcctctgt caatccagaa gtaggggaag
    39841 tacaggtcaa agaatatgct gaagctttgg agaaacatat cggctatcag ccaatttgct
    39901 ttattacaaa tgggttgaag cactatatac ttgatggtcc gaaccgccgc cagattgcag
    39961 gcttttactc tcaagaagaa ttgcaattag tgatggatag acgtcatctt caaaaaccgc
    40021 ttgaggatat ttctagtaaa attagggacg atatttccgg gcgtcactac caaaaacatg
    40081 ccattgcaag cgtttgtgaa gctttctctg atcatcgtag acaggcactt ttggttatgg
    40141 caactggggc ggggaaaact cgtacagcag tttctctagt tgatatctta tcacgtcata
    40201 actgggtaaa aaacgttctc ttcttagccg atagaacttc cttggttaag caagcatatg
    40261 attcgtttag aaaattactc ccagatcttt ccgtttgtaa cttcttagaa gataaagaag
    40321 gagctcaatc aagtcgaatg gtcttttcaa cttatccgac catgattgga gcgattagtg
    40381 gtcaagaaga agtaaatcaa cgccctttta ctgttgggca ttttgacctt atcataattg
    40441 acgaatctca ccgttctatt tatcagaaat acaagtccat ttttgattat tttgatgcaa
    40501 ggattgtagg cttaacagct actccgcgtc aagatttaga taaaaacacc tatggattct
    40561 ttaatttgga gaatggggtt ccaacatatg catatgattt ggaagaggct gttaaagacg
    40621 gatatttagt agcctatcat tctatcgaaa ccaaactgaa actacctacg gatggtctac
    40681 attatgatga tttgtccgaa gaagaaaagg aacattttga tagcaaattt gaagacgata
    40741 gctgtgaaaa agatattgat gggagtgtgt ttaattcctt tattttcaat aaaagtacag
    40801 tagaaattgt tttaaatgaa ctcatgacaa gaggaattca gacagcctcg ggtgatgaaa
    40861 ttggtaaaac tattattttt gctaaaaatc atgaccatgc ggaatatatc agaggtattt
    40921 ttaacaaccg ctatcctgaa aaagggagcg actatgctca ggtgattgat tatagtatta
    40981 agcattatca gaccttgatt gatgatttta aaattaagga gaagtatcct caaattgcga
    41041 tttctgtcga tatgttagat acaggtattg atgtaccaga ggttgttaat ttagtcttct
    41101 tcaagaaagt acgctctaaa actaagtttt ggcagatgat tggtcgagga acccgtctat
    41161 gtaaagattt atttggacct gagcaggata aggaaaactt cttggtattt gattatgggg
    41221 acaattttga ttattttcgt gcagatccaa gagatggaga gggtcgtcac attgtttcgc
    41281 tgactcagcg tttatttaat atcaaagtgg acttgattcg agaacttcag ggactccaat
    41341 accaagaaga tcagtttgcg agagcatacc gtcagcagct tgtctcggaa cttcaaggtc
    41401 gtatagagag cttaaatgag ttggacttca gggttcgtat ggttttagat acagtttata
    41461 gctataggaa attggaaagt tggcagaatc taactgctgt tacaagtgaa accattcaaa
    41521 aaaatctctc tccgctttta tttgatgaag ataaagaaga tgagatggcg aggagatttg
    41581 atttgtggtt gcttcatatt cagttggggc aactgacagc taaatcttcc actgttcata
    41641 tttcccaagt gatgaagacg gctagagctc tttctgctat tggcaatatc ccgcaggttt
    41701 ttgagcaggc tgaaattatg gctctttgtc aactgtagtg ggttgaaaaa aagctaagct
    41761 tgagaaagga caaattttgt cctttctttt ttgatattca gggcgataaa aatccgtttt
    41821 ttgaagtttt caaagttccg aaaaccaaag gcattgcgct tgataagttt gatgagatta
    41881 ttggtcgctt ccagtttggc attagaatag tgtagttgaa gggcgttgac gattttctct
    41941 ttgttcttta gaaaggtttt aaagacagtc tgaaaaagag gatgaacctg cttcagattg
    42001 tcctcaatga gtccgaaaaa tttctcaggg tctttgttct gaaagtgaaa aagtaagagt
    42061 tgatagatct gatagtggtg tttcaagtct tctgaatagc ttaaaatctt gtcaagaatt
    42121 tctttatttg ttaagtgcat gcgaaaagta gggcgataaa aacgtttatc gctcaattta
    42181 cgactatcct gttggatgag tttccagtaa cgcttgatag ccttgtattc atgagatttt
    42241 cgttcaaact gattcataat ttgaacacga aaacgactca tggcacggct gagatgttgg
    42301 ataatatgga aacgatctag aacgatttta gcacacggaa aaagctgttt agccaagtca
    42361 tagtaaggac taaacatatc catcgtaatg attttcactt gacaacgaac ggctctatcg
    42421 tagcgaagaa agtgatttcg gatgacagct tgtgttctgc cttcaagaac agtgataata
    42481 ttaagattat caaaatcttg cgcaatgaaa ctcatctttc ccttagtgaa ggcatactca
    42541 tcccaagaca taatctttgg aagccgagaa aaatcatgct caaagtgaaa gtcattgagc
    42601 ttgcgaatga cagttgaagt tgaaatggcc agctgatg
//
LOCUS       DAVBEO010000012        39682 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 009
            SAMEA1678075-rid20185393.denovo.012, whole genome shotgun sequence.
ACCESSION   DAVBEO010000012 DAVBEO010000000
VERSION     DAVBEO010000012.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678075
            Sequence Read Archive: ERR226392
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 39682)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 39682)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980207.1
            Genome Coverage       :: 150x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:50:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 72 of 147
            Pseudo Genes (incomplete)         :: 72 of 147
            Pseudo Genes (internal stop)      :: 42 of 147
            Pseudo Genes (multiple problems)  :: 32 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..39682
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678075-rid20185393.denovo.012"
                     /strain="KS 009"
                     /db_xref="taxon:1313"
     gene            <1..143
                     /locus_tag="VQ543_000683"
     CDS             <1..143
                     /locus_tag="VQ543_000683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000458116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="choline-binding protein D"
                     /protein_id="HET2611446.1"
                     /translation="LEASGAMKASQWFKVSDKWYYVNGLGALAVNTTVDGYKVNANGE
                     WV"
     gene            544..1665
                     /gene="mnmA"
                     /locus_tag="VQ543_000684"
     CDS             544..1665
                     /gene="mnmA"
                     /locus_tag="VQ543_000684"
                     /EC_number="2.8.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiouridine(34) synthase MnmA"
                     /protein_id="HET2611447.1"
                     /translation="MSDNSKTRVVVGMSGGVDSSVTALLLKEQGYDVIGIFMKNWDDT
                     DENGVCTATEDYKDVVAVADQIGIPYYSVNFEKEYWDRVFEYFLAEYRAGRTPNPDVM
                     CNKEIKFKAFLDYAMTLGADYVATGHYARVARDEDGTVHMLRGVDNGKDQTYFLSQLS
                     QEQLQKTMFPLGHLEKPEVRRLAEEAGLSTAKKKDSTGICFIGEKNFKNFLSNYLPAQ
                     PGRMMTVDGRDMGEHAGLMYYTIGQRGGLGIGGQHGGDNAPWFVVGKDLSKNILYVGQ
                     GFYHDSLMSTSLEASQVHFTREMPEEFTLECTAKFRYRQPDSKVTVHVKGDKAEVIFA
                     EPQRAITPGQAVVFYDGEECLGGGLIDNAYRDGQVCQYI"
     gene            1806..2261
                     /locus_tag="VQ543_000685"
     CDS             1806..2261
                     /locus_tag="VQ543_000685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HET2611448.1"
                     /translation="MTQQDFRTKVDNTVFGVRATALIVQNHKLLVTKDKGKYYTIGGA
                     IQVNESTEDAVVREVKEELDVKAQAGQLAFVVENRFEVDGVSYHNIEFHYLVDLLEDA
                     PLTMQEDEKRQPCEWIDLDKLQNIQLVPAFLKTALPDWEGQLRHIHLEE"
     gene            2271..4184
                     /gene="mnmG"
                     /locus_tag="VQ543_000686"
     CDS             2271..4184
                     /gene="mnmG"
                     /locus_tag="VQ543_000686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis enzyme MnmG"
                     /protein_id="HET2611449.1"
                     /translation="MTYHFTEEYDIIVIGAGHAGVEASLAASRMGCKVLLATINIEML
                     AFMPCNPSIGGSAKGIVVREVDALGGEMAKTIDKTYIQMKMLNTGKGPAVRALRAQAD
                     KELYSKEMRKTVENQENLTLRQTMIDEILVEDGKVVGVRTATHQEYAAKAVIVTTGTA
                     LRGEIIIGDLKYSSGPNHSLASINLADNLKELGLEIGRFKTGTPPRVKASSINYDVTE
                     IQPGDEVPNHFSYTSRDEDYVKDQVPCWLTYTNGTSHEIIQNNLHRAPMFTGVVKGVG
                     PRYCPSIEDKIVRFADKERHQLFLEPEGRNTEEVYVQGLSTSLPEDVQRDLVHSIKGL
                     ENAEMMRTGYAIEYDMVLPHQLRATLETKKISGLFTAGQTNGTSGYEEAAGQGIIAGI
                     NAALKIQGKPELILKRSDGYIGVMIDDLVTKGTIEPYRLLTSRAEYRLILRHDNADMR
                     LTEMGREIGLVDDERWARFEIKKNQFDNEMKRLDSIKLKPVKETNAKVEEMGFKPLTD
                     AVTAKEFLRRPEVSYQDVVAFIGPAAEDLDDKIIELIETEIKYEGYISKAMDQVAKMK
                     RMEEKRIPANIDWDDIDSIATEARQKFKLINPETIGQASRISGVNPADISILMVYLEG
                     KNRSISKTLQKSK"
     gene            4373..4462
                     /locus_tag="VQ543_000687"
                     /pseudo
     CDS             4373..4462
                     /locus_tag="VQ543_000687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(4608..6287)
                     /locus_tag="VQ543_000688"
     CDS             complement(4608..6287)
                     /locus_tag="VQ543_000688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HET2611450.1"
                     /translation="MAYTLKPEEVGVFAIGGLGEIGKNTYGIEYQDEIIIVDAGIKFP
                     EDDLLGIDYVIPDYSYIVDNIDRVKAVLITHGHEDHIGGIPFLLKQANVPIYAGPLAL
                     ALIRGKLEEHGLLRNAKLYEINHNTELTFKNLKATFFRTTHSIPEPLGIVIHTPQGKI
                     VCTGDFKFDFTPVGEPADLHRMAALGEEGVLCLLSDSTNAEVPTFTNSEKVVGQSIMK
                     IIQGIEGRIIFASFASNIFRLQQATEAAVKTGRKIAVFGRSMEKAIVNGIDLGYIKAP
                     KGTFIEPNEIKDYPAGEVLILCTGSQGEPMAALSRIANGTHRQVQLQPGDTVIFSSSP
                     IPGNTTSVNKLINIISEAGVEVIHGKVNNIHTSGHGGQQEQKLMLRLIKPKYFMPVHG
                     EYRMQKVHAGLAVDTGVEKDNIFIMSNGDVLALTADSARIAGHFNAQDIYVDGNRIGE
                     IGAAVLKDRRDLSEDGVVLAVATVDFKSQMILSGPDILSRGFVYMRESGDLIRQSQRI
                     LFNAIRIALKNKDASVQSVNGAIVNAIRPFLYENTEREPIIIPMILTPDEE"
     gene            complement(6289..6522)
                     /locus_tag="VQ543_000689"
     CDS             complement(6289..6522)
                     /locus_tag="VQ543_000689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-dependent RNA polymerase auxiliary subunit
                     epsilon family protein"
                     /protein_id="HET2611451.1"
                     /translation="MIYKVFYQETKERSPRRETTRALYLDIDASSELEGRITARQLVE
                     ENRPEYNIEYIELLSDKLLDYEKETGAFEITEF"
     gene            6904..7125
                     /locus_tag="VQ543_000690"
     CDS             6904..7125
                     /locus_tag="VQ543_000690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000184674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2611452.1"
                     /translation="MTNQVLEENYLCDSLLAFSPPRDLCRLVCILLWIKCLDALLMLG
                     FFVWGCRDSRFTTRKFHPIYQDEVVFAFF"
     gene            complement(7338..7490)
                     /gene="cibB"
                     /locus_tag="VQ543_000691"
     CDS             complement(7338..7490)
                     /gene="cibB"
                     /locus_tag="VQ543_000691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000977347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fratricide two-peptide bacteriocin subunit CibB"
                     /protein_id="HET2611453.1"
                     /translation="MMKDLNNCREISNKELQEIKGGFGVGVGIALFMAGYTIGKDLRK
                     KFGKSC"
     gene            complement(7492..7677)
                     /gene="cibA"
                     /locus_tag="VQ543_000692"
     CDS             complement(7492..7677)
                     /gene="cibA"
                     /locus_tag="VQ543_000692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000180803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fratricide two-peptide bacteriocin subunit CibA"
                     /protein_id="HET2611454.1"
                     /translation="MTNFDILDNQFLSLSENELSDIDGGLAPLVIFGVAVSWKAIAGG
                     TALIGSGLAAGYFLGGD"
     gene            7855..8538
                     /gene="tsaB"
                     /locus_tag="VQ543_000693"
     CDS             7855..8538
                     /gene="tsaB"
                     /locus_tag="VQ543_000693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000865689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     dimerization subunit type 1 TsaB"
                     /protein_id="HET2611455.1"
                     /translation="MKVLAFDTSSKALSLAILEDKQVLAETTINIKKNHSITLMPAID
                     FLMESLDWTPKDLDRIVVAEGPGSYTGLRIAVATAKTLTHTLNIELVGMSSLLALVPY
                     QQEGLFVPLMDARRNNVYAGFYENAKPVMPEAHLSFEEVLEKVKGASQVTFVGEVGPF
                     VEQIQEHLPRTNYKETLPNAANLALLAWDKEADSLHDFVPNYLKRVEAEENWLKNHTE
                     SGESYIKRL"
     gene            8535..8972
                     /gene="rimI"
                     /locus_tag="VQ543_000694"
     CDS             8535..8972
                     /gene="rimI"
                     /locus_tag="VQ543_000694"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000569806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HET2611456.1"
                     /translation="MIEIKRIQQQPDLAQAIYAVMAAVYLVSPWTLEQIQADLSQDQT
                     WYALAYDGAEVIGFLAVQENLFEAEVLQIAVKGAYQGQGIASALFAQLPTDKEIFLEV
                     RKSNQRAQAFYKKEKMAVIAERKAYYHDPVEDAIIMKREIDEG"
     gene            8962..9972
                     /gene="tsaD"
                     /locus_tag="VQ543_000695"
     CDS             8962..9972
                     /gene="tsaD"
                     /locus_tag="VQ543_000695"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002896630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
                     /protein_id="HET2611457.1"
                     /translation="MKDRYILAFETSCDETSVAVLKNDDELLSNVIASQIESHKRFGG
                     VVPEVASRHHVEVITACIEEALAEAGITEEDVTAVAVTYGPGLVGALLVGLSAAKAFA
                     WAHGLPLIPVNHMAGHLMAAQSVEPLEFPLLALLVSGGHTELVYVSEAGDYKIVGETR
                     DDAVGEAYDKVGRVMGLTYPAGREIDELAHQGQDIYDFPRAMIKEDNLEFSFSGLKSA
                     FINLYHNAEQKGESLSTEDLCASFQAAVMDILMAKTKKALEKYPVKTLVVAGGVAANK
                     GLRERLAAEITDVKVIIPPLRLCGDNAGMIAYASVSEWNKENFAGWDLNAKPSLAFDT
                     ME"
     gene            complement(10018..11318)
                     /locus_tag="VQ543_000696"
                     /pseudo
     CDS             complement(10018..11318)
                     /locus_tag="VQ543_000696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677188.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            complement(11594..11945)
                     /locus_tag="VQ543_000697"
                     /pseudo
     CDS             complement(11594..11945)
                     /locus_tag="VQ543_000697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(12052..12344)
                     /locus_tag="VQ543_000698"
                     /pseudo
     CDS             complement(12052..12344)
                     /locus_tag="VQ543_000698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            12587..13793
                     /locus_tag="VQ543_000699"
                     /pseudo
     CDS             12587..13793
                     /locus_tag="VQ543_000699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001200043.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
     gene            13786..14434
                     /locus_tag="VQ543_000700"
                     /pseudo
     CDS             13786..14434
                     /locus_tag="VQ543_000700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397244.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
     gene            14444..16060
                     /locus_tag="VQ543_000701"
     CDS             14444..16060
                     /locus_tag="VQ543_000701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000288036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2611458.1"
                     /translation="MYTIIKSNIKKFSLLTIFIVAGQLLLIYAATINALVLNELIAMN
                     LERFLKLSIYQMIVWCGIIFLDWVVKNYQVEVIQEFNLEIRNRVATDISNSTYQEFHS
                     KSSGTYLSWLNNDVQTLNDQAFKQLFLVIKGISGTIFAVVTLNHYHWSLTVATLFSLM
                     IMLLVPKIFASKMREVSLNLTNQNEAFLKSSETILNGFDVLASLNLLYVLPKKIKEAG
                     ILLKMVIQRKTTVETLAGAISFFLNIFFQISLVFLTGYLAIKGIVKIGTIEAIGALTG
                     VIFTALGELGGQLSSIIGTKPIFLKLYSINPIESNKMNDIEPNEVNRDFPLYEAKNIC
                     YKYGDKEILKNLNFCFQRNEKYLILGESGSGKSTLLKLLSGFLRDYSGELRFCGDDIK
                     KTSYLNMVSNVLYVDQKAYLFEGTIRDNILLEENYTDEEILQSLEQVGLSVKDFPNNI
                     LDYYVGDDGRLLSGGQKQKITLARGLIRNKKIVLIDEGTSAIDRRTSLAIERKILDRE
                     DLTVIIVTHAPHPELKQYFTKIYQFPKDFI"
     gene            16080..16924
                     /locus_tag="VQ543_000702"
                     /pseudo
     CDS             16080..16924
                     /locus_tag="VQ543_000702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813546.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            16992..18493
                     /locus_tag="VQ543_000703"
                     /pseudo
     CDS             16992..18493
                     /locus_tag="VQ543_000703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001819023.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine synthase"
     gene            18505..19254
                     /locus_tag="VQ543_000704"
     CDS             18505..19254
                     /locus_tag="VQ543_000704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000069862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PIG-L family deacetylase"
                     /protein_id="HET2611459.1"
                     /translation="MSDNTKYIFLSPHLDDAIFSCGDYISKLTSEGEIVLVITIFSGY
                     PLSQQLQPSAKQFHKLCNLGKYPIEERKKEDRLACERLQCDFRHLSYYECLYRKDRNG
                     NFLYRHIYSKLKNEDTLKNDIIKELLMHLDDKCVVYCPLSLGDHVDHVFVNSIGRALE
                     FMRYKVIYYEDFPYVSDSSMVSYMGKTKELKMYQEELDEKHYIDRISSILCYKSQILI
                     IWKSVEKLLNNIKELYLRNGAAYSIRFWIKK"
     gene            19267..20439
                     /locus_tag="VQ543_000705"
     CDS             19267..20439
                     /locus_tag="VQ543_000705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001017606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide sugar dehydrogenase"
                     /protein_id="HET2611460.1"
                     /translation="MNIAVIGLGHVGLAYALLFASKYKVVAYDIDSVKINNLKKGTLP
                     SKNEELMKFFCENNLNITFFDTFSEIKNNIDYYIIALPTDYDEKIGSFNTYEIEQTVS
                     KILRVKPNGKIILKSTVPIGFSNKLKRLFDTKNIIFVPEFLREGCSIYDNLYPSRIVV
                     GDETVEGRKIAELFLSISTHSTANIKNVMLVSPTEAEAIKLFSNTFLALRVAFFNELD
                     SFAERRSLNAEVVIKGVCLDPRIGNFYNNPSFGFGGYCLPKDTRQLKKEFIEINAPVI
                     EAIDISNTNRKQFIVKQILERKPKIVGIYKLGMKYNSDNYKESAILSIINELLIVGIK
                     ILVYEPNLNVSIDNVIFEKNFELFIKQSDLIVANRWDRGLEAYKDKVYTRGIWIRD"
     gene            20834..21697
                     /locus_tag="VQ543_000706"
     CDS             20834..21697
                     /locus_tag="VQ543_000706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000572848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE/MutR family transcriptional regulator"
                     /protein_id="HET2611461.1"
                     /translation="MIEKMELGEFYKELRLARKLKQSDVACAGLTASQLSKFELGQSM
                     LSADKLILAIQGINMNFDEFGHKLNNYQESPHMRIGRRVVDCFSHQDIAALEQLLEEV
                     DQEQMAQTYRRLNAIVIKNALHSLDKSYPLTEEDSEFLTTYLYAIESWTWFELYLFCN
                     TMPFLSNQDLIFLSTSLLEKSKEFKELVHNRWYMKSGYLNIISELMERKLFSYIPIFE
                     AELERMLRPYDVFEKVLWQFLKKMQIFLQTKGSNQKEIEHFIQSLQVLENPQLTALFE
                     LRLQQYKELID"
     gene            21983..22216
                     /locus_tag="VQ543_000707"
     CDS             21983..22216
                     /locus_tag="VQ543_000707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000933479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2611462.1"
                     /translation="MLNLQFAETMELTEAELQDVRGGNLVNSMGGGGRSGISGWGVPG
                     IYPGWGNQGMSPNRGAFDWTIDLADGLFGRRRR"
     gene            22238..22915
                     /locus_tag="VQ543_000708"
     CDS             22238..22915
                     /locus_tag="VQ543_000708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET2611463.1"
                     /translation="MKKMKEVKFHLATGLLILTYYLIFNVTSDLDFMVALSDNMYYVF
                     QVLLVLILGTIATIAFVKSEHWKECGRFQFRWSYLGVFLLSFFLLFVWANLTTYIFPR
                     TQNGSTVVEVATSLTGISYFVTRILYTSIIAPVSEEVVCRGLLMTSLSKVKRYYLDVL
                     VSAAIFGAMHVLQYGWITTDFIKYFGMGLIFCMMFRYTRSIYWAIALHASWNSFLLIV
                     TLLVFGY"
     gene            22927..23592
                     /locus_tag="VQ543_000709"
     CDS             22927..23592
                     /locus_tag="VQ543_000709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000720786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET2611464.1"
                     /translation="MKKIISHRYFIIVFLLVIADQKFSVLVLRSDLVAGLSDFAYYLS
                     DMMLNFLVVLFALIAMIWSGKWQKINSRKFKGSYLFYSFLALLAFVAWNFVTFFLFPP
                     TRNEISYQHAAPTFTGATAFLMYFFYPVIAGPIFEDMIYRGLVMTALEKGKKWGLDVL
                     GSAILFGVSHISNHGWVLTDFFVYMGGGLIFAVLFRMTKSIYWPIGLHIVYNGIGQLL
                     MLL"
     gene            23664..24890
                     /locus_tag="VQ543_000710"
     CDS             23664..24890
                     /locus_tag="VQ543_000710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000862399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HET2611465.1"
                     /translation="MKVFLQNRDFRQLTINQWISTLGDTIFYLAFLNYVADASFAPLA
                     ILLITISETLPQVLQIFLGVLADFQHHRVLKYTVISFTKFLLYSIVSLSLSGQSFSLL
                     LVTFICLLNLLSDTLSYFSGAMLTPIFIRIIGQDHLAEAIGFKQSTVSLVKTISNILG
                     GVLLGILSIQFISLLNALTFLIAFLGILFIKTDLLKVEKTISYQEGLSVKSFCQHLLQ
                     SSKLIWNMNKVLLVLFIISTSQAVINVTVPISTLFLRNQPFLNLQTGQSLALLATLEL
                     SALILGSLMSGYLQHTISIKIALYASLLLQLLLLVGFATAHFGLILIFSFLDAFFAGI
                     LSPRLQELVFKQIPEESMGAVQSSIGAITVVLPSLFTIALGTIATSFGTLAVSFVLLL
                     FLLVAFVMLLNIRESI"
     gene            complement(25241..25318)
                     /locus_tag="VQ543_000711"
                     /pseudo
     CDS             complement(25241..25318)
                     /locus_tag="VQ543_000711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            25389..26045
                     /locus_tag="VQ543_000712"
     CDS             25389..26045
                     /locus_tag="VQ543_000712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001141648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HET2611466.1"
                     /translation="MPTALGYVSIGLACGTIGAPYVTPVEMGLMSLFVYAGSAQFAML
                     ALIVVQAPVAAIAMTVFLINLRLFLLSLHASTYFRHTSLWYNIGMSSILTDETYGVLM
                     GELAHTDKVNPMWMHGNNLNSYVAWFVGTVVGTALGGLLPNPEIFGLDFALVGMFIGI
                     FASQFQIMQRRIPVRNLLIILAVVAVSFFLLLTVVSQSLAVLFATLLGCSMGVVLDGQ
                     "
     gene            26035..26358
                     /locus_tag="VQ543_000713"
     CDS             26035..26358
                     /locus_tag="VQ543_000713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000253911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HET2611467.1"
                     /translation="MVSKYLLLAVIFSDLVTWILRMIPFILVKYKGLPAIVERFLKFL
                     PVSIIFALILSSVVTGKVGSLPQIKWLDFLAVFPTAWVAFRYRNLVGTVLFGVVLIAV
                     LRLVF"
     gene            26462..27292
                     /locus_tag="VQ543_000714"
     CDS             26462..27292
                     /locus_tag="VQ543_000714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HET2611468.1"
                     /translation="MKKIVKYSSLAALGLVAAGVLAACSGGAKKEGQAASKKEIIVAT
                     NSSPKPFNYEENGELTGYEIEVVRAIFKDSDKYDVKFEKTEWSGVFAGLDADRYQMAV
                     NNISYTKERAEKYLYAAPTVKDPNVLVVKKDDSSIKSLDDVGGKSTEVVQGTTSAKQL
                     EDYNKQHSDNPTILNYTKANLQQIMGHLSDGQFDYKISDKITVETVIKNQGLDNLKVI
                     DLPSDQQPYVYPLLAKGQDELKTFVDKRIQELYKDGTLEKLSKQFFGDTYLPAEADIK
                     "
     gene            27333..27410
                     /locus_tag="VQ543_000715"
                     /pseudo
     CDS             27333..27410
                     /locus_tag="VQ543_000715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000253911.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC protein"
     gene            27514..28344
                     /locus_tag="VQ543_000716"
     CDS             27514..28344
                     /locus_tag="VQ543_000716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HET2611469.1"
                     /translation="MKKIVKYSSLAALALVAAGVLAACSGGAKKEGQAASKKEIIVAT
                     NGSPKPFIYEENGELTGYEIEVVRAIFKDSDKYNVKFEKTEWSGVFAGLDADRYNMAV
                     NNLSYTKERAEKYLYAAPIAQNPNVLVVKKDDSSIKSLDDIGGKSTEVVQATTSAKQL
                     EAYNAEHTDNPTILNYTKADFQQIMVRLSDGQFDYKIFDKIGVETVIKNQGLDNLKVI
                     ELPSDQQPYVYPLLAQGQDELKSFVDKRIKELYKDGTLEKLSKQFFGDTYLPAEADIK
                     "
     gene            28498..29352
                     /locus_tag="VQ543_000717"
     CDS             28498..29352
                     /locus_tag="VQ543_000717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000694494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HET2611470.1"
                     /translation="MKIKKWLGLAALATVAGLALAACGNSEKKADNATTIKIATVNRS
                     GSEEKRWDKIQELVKKDGITLEFTEFTDYSQPNKATADGEVDLNAFQHYNFLNNWNKE
                     NGKDLVAIADTYISPIRLYSGLNGSANKYTKVEDIPANGEIAVPNDATNESRALYLLQ
                     SAGLIKLDVSGTALATVANIKENPKNLKITELDASQTARSLSSVDAAVVNNTFVTEAK
                     LDYKKALFKEQADENSKQWYNIIVAKKDWETSPKADAIKKVIAAYHTDDVKKVIEESS
                     DGLDQPVW"
     gene            29452..30825
                     /locus_tag="VQ543_000718"
     CDS             29452..30825
                     /locus_tag="VQ543_000718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20/M25/M40 family metallo-hydrolase"
                     /protein_id="HET2611471.1"
                     /translation="MVFPSEQEQIEKFEKDHVVQHYFEVLRTLISKKSVFAQQVGLKE
                     VANYLGEIFKRVGAEVEIDESYTAPFVMAHFKSSRPDAKTLIFYNHYDTVPADGDQVW
                     TEDPFTLSVRNGFMYGRGVDDDKGHITARLSALRKYMQHHDDLPVNISFIMEGAEESA
                     STDLDKYLEKHADKLRGADLLVWEQGTKNALEQLEISGGNKGIVTFDAKVKSADVDIH
                     SSYGGVVESAPWYLLQALQSLRAADGRILVEGLYEEVQEPNEREMALLETYGQRNPEE
                     VSRIYGLELPLLQEERMAFLKRFFFEPALNIEGIQSGYQGQGVKTILPAEASAKLEVR
                     LVPGLEPHDVLEKIRKQLDKNGFDKVELYYTLGEMSYRSDMSAPAILNVIELAKKFYP
                     QGVSVLPTTAGTGPMHTVFDALEVPMVAFGLGNANSRDHGGDENVRIADYYTHIELVE
                     ELIRSYE"
     gene            30818..31879
                     /locus_tag="VQ543_000719"
     CDS             30818..31879
                     /locus_tag="VQ543_000719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter ATP-binding protein"
                     /protein_id="HET2611472.1"
                     /translation="MSRDIIKLDQIDVTFHQKKRTITAVKDVTIHIQEGDIYGIVGYS
                     GAGKSTLVRVINLLQKPSAGKITIDDDVIFDGKVTLTAEQLRRKRQDIGMIFQHFNLM
                     SQKTAEENVAFALKHSGLSKEEKKAKVAKLLDLVGLADRAENYPSQLSGGQKQRVAIA
                     RALANDPKILISDESTSALDPKTTKQILALLQDLNQKLGLTVVLITHEMQIVKDIANR
                     VAVMQDGHLIEEGSVLEIFSNPKQPLTQDFISTATGIDEAMVKIEKQEIVEHLSENSL
                     LVQLKYAGASTDEPLLNELYKHYQVMANILYGNIEILDGTPVGELVVVLSGEKAALAG
                     AQEAIRQAGVQLKVLKGGQ"
     gene            31881..32573
                     /locus_tag="VQ543_000720"
     CDS             31881..32573
                     /locus_tag="VQ543_000720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET2611473.1"
                     /translation="MESLIQTYLPNVYKMGWAGQAGWGTAIYLTLYMTVLSFIIGGFL
                     GLVAGLFLVLTAPGGVLENKVVFWILDKITSIFRAVPFIILLAILSPLSHLIVKTSIG
                     PNAALVPLSFAVFAFFARQVQVVLAELDGGVIEAAQASGATFWDIVGVYLSEGLPDLI
                     RVTTVTLISLVGETAMAGAVGAGGIGNVAIAYGFNRYNHDVTILATIIIILIIFAIQF
                     LGDFLTKKLSHK"
     gene            complement(32603..33172)
                     /locus_tag="VQ543_000721"
     CDS             complement(32603..33172)
                     /locus_tag="VQ543_000721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000748387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HET2611474.1"
                     /translation="MKKSILTTLLFAVLYFLCMGIGVLLGNLFDQTGNMFYAPAFTAL
                     VGGSVYMILVAKVPRFGAITTIGLVIALFFLGTKHGAGSFLPGIICGLLADGVAHLGK
                     YKDKTKNFLSFIIFAFSTTGPILLMWIAPKAYMATLLARGKSQEYIDRIMVAPNPGTV
                     LLFIASIVIGALVGALIGQALSKKFAQKI"
     gene            33307..33921
                     /locus_tag="VQ543_000722"
     CDS             33307..33921
                     /locus_tag="VQ543_000722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000532354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HET2611475.1"
                     /translation="MGRFLDFVFNRFFLGMIATAFFWLLTLAGGIILGLAPASATLMS
                     LYAEHGYSFREYSLKEAWSLYKQNFVSSNLIFYSFLGVGLVLTYGLYLLVQLPHQTIV
                     HLIATLLNVLVVALIFLAYTVSLKLQVYFALSYRNSLKLSLIGIFMSLAAVAKVLLGT
                     VLLVAIGYYMPALLFFVGIGMWHFFISDMLEPVYEIIHEKLATK"
     gene            33923..35569
                     /locus_tag="VQ543_000723"
     CDS             33923..35569
                     /locus_tag="VQ543_000723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013670288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HET2611476.1"
                     /translation="MKQFWLHTLLRTYSSVMIIIIASFAILLSYADWDSREKEAQRVA
                     QRVTARTVSEIEYYHRESTQIAQALVENQARIEGIYKYFSLSMPDYFYWQLERKASPY
                     ISVSLYENVDDLYVRNDFVTGVAIAFQDYKEVYVSTKDKRSGEKIRAEDFKPAGNSFA
                     IPVSDPVSDQDLGVIYISLDPAVLYHAIDNTRGHTPMAVTVTSPFDTEIFHIGETVDR
                     ESENWLVGLTSHGYQVQVAVPKNFVLQGTVTSSALIVGLSLLFIVILYLTLRQTFANY
                     QKQVVDLVESIQVIAQGEEGRRIDISEKDQELLLIAETTNDMLDRLEKNIHDIYQLEL
                     SQKDANMRALQAQINPHFMYNTLEFLRMYAVMQSQDELADIIYEFSSLLRNNISDERE
                     TLLKQELEFCRKYSYLCMVRYPKSIAYGFKIDPELENMKIPKFTLQPLVENYFAHGVD
                     HRRTDNVISIKALKQDGFVEILVVDNGRGMSAEKLANIREKLSQKYFEHRASYSDQRQ
                     SIGIVNVHERFVLYFGDRYAITIESAEQAGVQYRITIQDE"
     gene            35581..36867
                     /locus_tag="VQ543_000724"
     CDS             35581..36867
                     /locus_tag="VQ543_000724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000278884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET2611477.1"
                     /translation="MYKVLLVDDEYMVTEGLKRLIPFDKWDMEVVATASHADEALEYV
                     QENPVDVIISDVNMPDKTGLDMIREMKEILPDAAYILLSGYQEFDYVKRAMNLSVVDY
                     LVKPVDKVELGNLLEKIAGQLGERGKKSQTLSQELDEAGFVSYLGDKENWWIGLSKEK
                     QGSFTIPYYVLGQDWQIFISDQPLDGLVVTPFEAPYQEHFERWKLNAEKTLFYGSVNL
                     QQSESLFAYYEPIYRVIIQGNLNQIVEELNLLEKVVLENTPRVPITKQLFIQFVMDVF
                     HLFEHLKADDLTDIVKTIHAIQSFDELVPYIKETLSSFFGQYRMNENVVSVLEVIGCD
                     YQKELSLKDISKALFINPVYLGQLIKRETDSTFAELLNKQRIKAAQQLLLSTSDSIED
                     ICYAVGYSNLGYFYKVFRKLCGKSPKAYRKQVETIL"
     gene            36928..37461
                     /locus_tag="VQ543_000725"
     CDS             36928..37461
                     /locus_tag="VQ543_000725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET2611478.1"
                     /translation="MKKKPIYLWVLLILSALISVPSLFGIVSPLPSKEALRTAQKQVA
                     GVNAQQLEDQLNYTYRVAEASHSIFNVALIVLSTILVVVAIVFLVRKNLQYANYTYVG
                     YVLLAIIGSIYGYVGLQDAVQLVQDESMRLTVSIGSKAVSIFYIVINVLFLALVFYKM
                     WRQQKASAEEEETEELA"
     gene            37539..38009
                     /gene="nrdI"
                     /locus_tag="VQ543_000726"
     CDS             37539..38009
                     /gene="nrdI"
                     /locus_tag="VQ543_000726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000849618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HET2611479.1"
                     /translation="MKIISLVYISLSGNTESFVTRLKDYLLSQYKGIEVQKIHIKDLV
                     KEGKNFYEMDHPYVAFLPTYLEGGNGVDNGDVEILTTPVGDFIAYGNNASKCFGVVGS
                     GNRNFNNQYCLTAKQYSQRFGFPVLADFEMRGMLEDIKHVAAIIADLYELEKEN"
     gene            complement(38302..39564)
                     /locus_tag="VQ543_000727"
     CDS             complement(38302..39564)
                     /locus_tag="VQ543_000727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000075801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="divalent metal cation transporter"
                     /protein_id="HET2611480.1"
                     /translation="MSQAISLNQSTWASKLKAMGPGILMATAAVGGSHIVSSTQAGGS
                     YGWSLLLLVILANVFKYPFFRFGAEYTADTGKTLVEGYAEKGKLYLWIFFILNVFSAM
                     VNTAGVAILCSAIIASAFPMIGLSITQWSLILVAIIWAMLLFGGYKLLDGMVKWIMSA
                     LTIATVLAVIIAAVKHPEYSSDFVEKTPWQMAALPFIVSLLGWMPAPIEISAINSLWS
                     AEKRKTVNFNTEDALFDFNTGYIGTAILAVFFVALGALIQYPTGQAVEAASAKYISQF
                     VGMYASVLGEWSRYLITFIAFLCIFGTVITVIDGYSRVNQESLRLLISQKEDNRKSLN
                     IWMTITAIIGIVIIKFFSGQVSTMLRFAMIGSFLTTPFFALLNYALVTRENKNLPSWL
                     KHLAIAGLIFLFGFAIFFIYALAIGKAG"
BASE COUNT        12052 a         6873 c         8559 g        12198 t
ORIGIN      
        1 atcttgaagc atcaggtgct atgaaagcaa gccaatggtt caaagtatca gataaatggt
       61 actatgtcaa tggtttaggt gcccttgcag tcaacacaac tgtagatggc tataaagtca
      121 atgccaatgg tgaatgggtt taagccgatt aaattaaatc atgttaagaa catttgacat
      181 tttaattttg aaacaaagat aaggttcgat tgaatagatt tatgttcgta ttctttaggt
      241 acctatctta tgatttcagg aaatgtcatt aaaaaaacga ctccttttct ctaacttgaa
      301 aaatagatta gagaaaatgg gttgttttat ttattatagt tatttgaatg aagataagaa
      361 gaaggtatac tcacatcatt cacataatct gtatgttgac tataagttta aaaaaacaat
      421 ttttaagctc ttccttgtct tctccaacca agcgtgttat aatgaatact gctcaagcga
      481 ccttcaatcg tgaagcacac acgaccttca atcgtgaata aacgaataga tgggagactt
      541 accatgagtg ataactctaa aacacgtgtt gtcgtgggga tgagtggtgg tgttgattcg
      601 tcggtgacgg ctcttttgct caaggagcag ggctacgatg tgatcggtat cttcatgaag
      661 aactgggatg acacagatga aaacggcgtc tgtacggcga ccgaagatta caaggatgtg
      721 gttgcggtgg cagaccagat tggcattccc tactactctg tcaattttga aaaagagtac
      781 tgggaccgcg tttttgagta tttcctagcg gaataccgtg cagggcgcac gccaaatccg
      841 gacgttatgt gcaacaagga aatcaagttc aaggcctttt tggactatgc catgaccttg
      901 ggggcagact atgtagcgac tgggcattat gctcgagtgg cgcgtgatga ggacggcact
      961 gttcacatgc ttcgtggcgt ggacaatggc aaggaccaga cctatttcct cagccaactt
     1021 tcgcaagaac aactccaaaa aaccatgttc cctctgggac atttggaaaa gcctgaagta
     1081 cgcagactag cagaagaagc aggcctttcg actgctaaga agaaagactc gacagggatt
     1141 tgctttatcg gagaaaagaa ctttaaaaac tttctcagca actacctgcc agctcagcct
     1201 ggtcgcatga tgactgtgga tggtcgcgat atgggcgagc atgcaggtct tatgtactat
     1261 acaatcggtc agcgtggcgg actcggtatc ggtgggcaac acggcggtga caatgcccct
     1321 tggttcgttg tcggaaaaga tctaagcaag aatattctct atgtaggaca aggattctac
     1381 catgattcgc tcatgtcaac tagcctagaa gccagtcaag tccactttac tcgtgaaatg
     1441 ccagaagagt ttacgctaga atgtacggct aaattccgtt accgtcagcc tgactctaag
     1501 gtgaccgtcc atgtcaaagg agacaaggca gaagttatct ttgcggaacc acaacgcgcg
     1561 attacaccag gacaggcagt tgtcttttac gatggcgaag agtgtctagg tggcggtttg
     1621 attgacaatg cttaccgcga tggacaagtt tgtcagtaca tttagattga caaattttct
     1681 caatttgcta caataataac agcaatagaa atgatggtca aagctcatgg atgttgcagg
     1741 cttttttgtc ctgcacttct ttgtagtttt gactgttttt gtgtcgttta agggaaagga
     1801 caagaatgac tcaacaagac tttcggacaa aagtagacaa tacggttttt ggtgttcggg
     1861 ctacagcctt gattgtccaa aatcacaagc ttctagttac caaagacaag ggcaagtatt
     1921 acactattgg aggtgcgatt caagtcaatg aaagcacgga agacgcggta gtccgtgaag
     1981 tgaaggaaga actggatgtc aaagctcaag ctgggcagct agcttttgtg gttgaaaatc
     2041 gttttgaagt ggacggcgtt tcctatcaca atatcgagtt tcattatctg gtggatttgc
     2101 ttgaagatgc cccgttgacc atgcaggaag atgagaaaag gcagccctgt gagtggattg
     2161 acttggataa gctccagaat atccagctag ttccagcctt tttaaaaaca gccctaccag
     2221 attgggaagg ccaactaaga cacattcatc ttgaggaata ggagagaaac atgacttatc
     2281 attttactga agaatacgat attattgtaa ttggtgcggg acacgctggg gttgaggctt
     2341 ccttggccgc tagccgtatg ggctgtaagg tcctgcttgc gaccatcaat attgaaatgc
     2401 tggctttcat gccttgtaat ccctctatcg gtggttctgc taaggggatt gtcgtacgtg
     2461 aagtcgatgc cctcggtggc gagatggcca agaccattga caagacttac atccagatga
     2521 agatgctcaa cacagggaag ggaccagccg ttcgtgccct tcgtgcgcag gctgataagg
     2581 aactttactc taaggaaatg cgcaagacag ttgaaaatca agaaaatctg acccttcgtc
     2641 aaaccatgat tgatgagatt ttggtggaag atggcaaggt tgtcggtgtg cgtacagcca
     2701 cccatcaaga atatgctgct aaggctgtta ttgtgacgac agggactgct ctccgtgggg
     2761 aaattatcat cggagacctc aagtactcat caggtcctaa ccacagcttg gcttctatta
     2821 acctagctga caatctcaag gaactgggtc tcgaaatcgg tcgtttcaag acaggaaccc
     2881 ctccacgtgt caaggcttct tctatcaatt acgatgtgac ggaaattcag ccaggagacg
     2941 aagtgcctaa tcatttctca tacacttcac gtgatgagga ttatgtcaaa gatcaagtgc
     3001 catgctggtt gacctatacc aatggtacca gtcatgagat tatccaaaac aacctccacc
     3061 gtgcgcctat gtttacaggt gtggtcaagg gagtggggcc tcgttactgt ccgtcgattg
     3121 aagacaagat tgtgcgcttt gcggacaagg aacgtcacca actcttcctt gagccagaag
     3181 ggcgcaatac tgaggaagtc tatgttcaag gactttcaac cagtctgcct gaggatgtcc
     3241 agcgtgactt ggttcattcc atcaaaggtt tggaaaatgc agagatgatg cggacaggtt
     3301 atgctattga gtatgatatg gtcttgcctc atcagttgcg tgcgactttg gaaaccaaga
     3361 aaatctcagg tctcttcact gctggtcaga caaatggaac atcaggttat gaagaagctg
     3421 ctggccaagg gattatcgcg ggtatcaatg cggctctgaa aatccaaggt aaacctgagt
     3481 tgattctaaa acgaagtgac ggttatatcg gggtgatgat cgacgacttg gtgaccaagg
     3541 gaaccattga accttaccgt ctcttgacca gtcgtgctga ataccgtctc attcttcgtc
     3601 atgacaatgc tgatatgcgc ttgactgaga tgggacgcga gattggcctt gtggatgatg
     3661 aacgctgggc tcgttttgaa atcaagaaaa atcaatttga taatgagatg aaacgcctag
     3721 acagtatcaa actcaagcca gtcaaggaaa ccaatgctaa ggttgaggaa atgggcttca
     3781 agccgttgac agatgcggtg acagccaagg aattccttcg ccgtccagaa gtttcttacc
     3841 aagatgtggt ggccttcatc ggaccagctg cagaagactt ggatgacaag attatcgaat
     3901 tgattgaaac agaaatcaag tacgaaggct atatttccaa agccatggat caggttgcta
     3961 agatgaaacg tatggaagaa aaacgcattc cagccaatat cgactgggat gacatcgatt
     4021 ctattgcgac ggaagctcgt cagaagttca aactcatcaa tccagaaacc atcggccaag
     4081 ccagccgtat ttcgggagta aacccagcag atatttctat tttgatggtg tatctggaag
     4141 gtaaaaatcg tagtatttct aaaactcttc aaaaatcaaa atgatacgtc gtcggcttct
     4201 tacgaatgag ttcaaagctt ggctttgatt catctccaac ctcccatagt tccccgaact
     4261 atgggagcta actcaagtta tgcattttcc tagccttctg gtctgatttt cattgagttt
     4321 taatctcaaa agaaagcata gagaaaaaca gctccgaaga cggggctgtt ttgttgactt
     4381 gtactcaatg aaaatcaaag agcaaactag gaagctagcc gtaggttgct caaagcactg
     4441 ctttgaggtt gtagatagaa ctgacgaagt cagctcaaaa cacagttttg aggttgtaga
     4501 tagaactgac gaagtcagct caaaacacag ttttgaggtt gtggatagaa ctgacgaagt
     4561 cagtaacata tatacggcaa ggcgaagctg acgtggtttg aagagtatta ttcttcatct
     4621 ggtgtgagga tcatcgggat gatgatcggt tcacgttcgg tattttcata gaggaagggg
     4681 cgaatagcgt tgacaatggc accattgaca gattgcacgc tagcatcctt atttttcagt
     4741 gcgatacgaa tggcattgaa gaggatacgc tggctttggc gaatcaagtc tccagactct
     4801 ctcatgtaga caaagcctcg gctgaggata tctgggccag acagaatcat ctgcgatttg
     4861 aagtcaacag ttgcgactgc cagaacgaca ccgtcttcag atagatcgcg acgatctttg
     4921 aggacagctg cgccaatttc accgatacga tttccatcga catagatatc ttgggcgttg
     4981 aaatgacctg cgatacgagc tgagtcagca gtaagggcaa gcacatcgcc attgctcatg
     5041 ataaagatat tgtctttctc aacaccagta tccactgcta gtccagcgtg gactttttgc
     5101 atgcggtatt caccgtggac aggcatgaag tattttggct taatcaagcg gagcatgagt
     5161 ttttgctctt gctgaccacc gtgtccagat gtatggatat tgttcacttt accgtggata
     5221 acttcgacac cagcttcaga aatgatgtta atcagcttgt tgacgctagt agtgtttcca
     5281 gggatgggac tagaagagaa gataacggta tcacctggtt gtaattgtac ttgacggtgg
     5341 gttccgttgg cgatacgaga gagggctgcc ataggctcac cctgactacc tgtacagagg
     5401 ataagaactt ctcctgcagg ataatctttg atttcatttg gctcgataaa ggttccctta
     5461 ggagctttga tgtagccaag atcgattccg ttgacaatgg ccttttccat agaacgacca
     5521 aagaccgcaa tcttgcgtcc agtcttaaca gcagcttctg ttgcctgctg gagacggaag
     5581 atatttgagg caaaggatgc aaagatgata cgtccttcaa taccttggat aatcttcata
     5641 atggactgac caacgacttt ttcagagttg gtaaaggttg gtacttccgc atttgtcgag
     5701 tcagacagga gacagagcac gccttcttca ccaagcgcag ccatacgatg caagtccgca
     5761 ggttctccaa ctggagtaaa gtcgaactta aagtcacccg tacagacgat tttcccttga
     5821 ggagtatgaa tgacaatccc caaaggctct ggaatagagt gagtcgttct aaagaaagtt
     5881 gccttgagat ttttaaaggt caactcggtg ttgtggttga tttcgtaaag tttggcgttg
     5941 cgcaagaggc cgtgttcttc gagtttccca cggatcaaag ccaaggcaag cggtccagcg
     6001 tagataggga catttgcttg cttgagtagg aacggaatcc caccaatgtg gtcctcgtgt
     6061 ccgtgtgtga ttaaaacagc cttgacgcgg tcgatattgt ctacgatgta agagtagtca
     6121 ggaatgacat agtcgatacc aagcaagtca tcttctggga atttaatccc agcatcgacg
     6181 atgataatct cgtcttggta ttcaattccg taagtgtttt tcccgatttc tcctagacca
     6241 ccgatggcaa aaacaccgac ttcttcaggt ttaagagtgt aggccatatt agaactccgt
     6301 aatttcgaag gcgccagttt ctttttcgta atcgagcaat ttgtcagaca agagttcgat
     6361 atattcgata ttgtactctg ggcgattttc ttcgacaagt tggcgagcag tgatacggcc
     6421 ctcaagttct gagctggcat cgatgtctag gtaaagcgcg cgtgttgttt cacggcgtgg
     6481 gctacgttct tttgtttctt gataaaaaac tttgtaaatc atatagttcc tttctattta
     6541 caggtcagct tattccaaac ttttagcaga tatttgcttg atttcattcc attttgtgtc
     6601 tagattgacc ttgattcgtt acaattattt caattatacc acaaaatgaa aaattagtaa
     6661 aagacggaaa cgagaaagtt aggggacgat ttcttcggta agcgtttgca aaaacaaaga
     6721 aaatgtgtta tgttgataac ggaagtgaag tttattactt gtcataattc catatagatt
     6781 ttaagtcaag gaggttgccc tatgtataac ttatttgctt ttgctatcgg agttcgtttg
     6841 ctagctttta tcgtttttgt tttgcgttta tggaggaaat cttctatttg ccaaactgga
     6901 acgatgacaa accaagttct tgaggaaaat tacctttgtg actctctact cgctttttct
     6961 cctcctcgtg acctatgtcg tttggtttgt attttacttt ggattaaatg cttagatgcc
     7021 ctgcttatgc tggggttttt tgtttgggga tgtagagata gtagatttac gacacgaaaa
     7081 ttccacccca tctatcaaga tgaggtggtc tttgcatttt tctaaaatga tatgacaatg
     7141 gaattttcaa agcttattat ttttatggga gtcattgttc tgctcaaaaa tagagttgaa
     7201 gcataaaaat aaaacaatac aaacagataa atcgaatggt aaagggatgg tagtaatgtt
     7261 caaatcattg agaatgctga gcaaactgta agagatgaag acaataaaat ttatccttct
     7321 aaaaatgtgt ttcttatcta gcatgactta ccaaactttt tacgaaggtc ttttccaatg
     7381 gtataacctg ccataaataa agcgatacca acacctacac caaagccacc cttgatttct
     7441 tgcaattcct tattagaaat ttcacgacag ttgttcaaat ctttcatcat attaatctcc
     7501 tcctaaaaaa taaccagctg ccaaaccaga acctataagt gctgttccac ctgcaatagc
     7561 tttccaagat actgctactc caaagataac caagggagcg agaccgccat caatatctga
     7621 taattcattt tcagataagg ataaaaattg attgtcaaga atgtcaaaat ttgtcattga
     7681 actttcctcc ttttttcttg ttcactttta tattcggaaa agaaaaggaa aagtgagcat
     7741 ttttttaaat tatttttagt taagtgaggg cactcttgtc tgggggcaaa gaaaattccc
     7801 atgtgccatc ttttgtagta taatagtaag cagacaaaaa gataggaatg tgttatgaaa
     7861 gtattagctt ttgatacgtc cagcaaggct ctttctctcg ctattttaga ggataagcag
     7921 gttcttgccg agacgacgat taatatcaag aaaaatcaca gtattaccct catgccagcc
     7981 attgattttt tgatggagag tttggactgg acgcccaagg atttggaccg aatcgtggtg
     8041 gcggaagggc caggtagcta cacaggcttg cgaatcgcgg tagccactgc caagaccttg
     8101 actcatactc tgaacattga gttagttggt atgtctagcc tcttggctct ggtgccatat
     8161 caacaagaag gcttgttcgt tcctttgatg gatgcgcgtc gcaacaatgt ttatgcagga
     8221 ttttatgaaa atgctaaacc tgtcatgcca gaagcgcacc tatcttttga agaggtgcta
     8281 gaaaaagtca agggtgctag tcaggtaacc tttgtcggag aagttggccc ctttgtggag
     8341 cagattcaag aacacttgcc aaggactaat tataaagaaa ccttgcctaa tgcagccaat
     8401 cttgctcttt tagcttggga caaggaagca gactccttgc atgattttgt gccaaattac
     8461 ctcaaacgag tcgaggctga ggaaaactgg ctcaagaacc ataccgagtc tggtgagtcc
     8521 tacattaaac gcctatgata gaaatcaagc gaattcaaca acagcctgac ctagctcaag
     8581 ccatctacgc tgttatggca gctgtttacc tagtcagtcc ttggactctg gagcaaatcc
     8641 aagcagatct gtcccaagac cagacttggt atgcattggc ttatgatggg gcagaagtga
     8701 ttggatttct agctgtgcag gagaatcttt ttgaagcaga agtcctgcaa atcgctgtca
     8761 aaggagctta tcagggtcag ggaattgcgt cagccttgtt tgctcaattg ccgacagata
     8821 aggagatttt cctcgaagtc agaaagtcaa atcaacgagc gcaagcattt tacaagaaag
     8881 aaaaaatggc ggtcatcgct gagcgaaagg cctactacca tgacccagtc gaggacgcca
     8941 ttatcatgaa gagagaaata gatgaaggat agatatattt tagcatttga gacatcctgt
     9001 gatgagacca gtgtcgccgt cttgaaaaac gacgatgagc tcttgtccaa tgtcattgct
     9061 agtcaaattg agagtcacaa acgttttggt ggcgtagtgc ccgaagtagc cagtcgtcac
     9121 catgtcgagg tcattacagc ctgtatcgag gaggcattgg cagaagcagg gattaccgaa
     9181 gaggacgtga cagctgttgc ggttacctac ggaccaggct tggtcggagc cttgctagtt
     9241 ggtttgtcag ctgccaaggc ctttgcttgg gctcacggac ttccactgat tcctgttaat
     9301 cacatggctg ggcacctcat ggcagctcag agtgtggagc ctttggagtt tcccttgcta
     9361 gccctcttgg tcagcggcgg acacacagag ttggtttatg tttcggaggc aggagattat
     9421 aagattgttg gggaaacccg tgatgatgcg gttggtgagg cttatgataa ggtcggccgt
     9481 gtcatgggct tgacctatcc tgcaggtcgt gagattgacg agctggctca tcaggggcag
     9541 gatatttatg atttcccccg tgccatgatt aaggaagata atctggagtt ctccttctca
     9601 ggtttgaaat ctgcctttat caatctttat cacaatgccg agcaaaaggg agaaagcctg
     9661 tctacagaag atttgtgtgc ttccttccaa gcagcagtta tggacattct catggcaaaa
     9721 accaagaagg ctttggagaa atatcctgtt aaaaccctgg ttgtggcagg tggtgtggca
     9781 gccaataaag gtctcagaga acgcctagca gccgaaatca cagatgtcaa ggttatcatc
     9841 ccccctctgc gactctgcgg agacaatgca ggtatgattg cctatgccag cgtcagcgag
     9901 tggaacaaag aaaacttcgc aggctgggac ctcaatgcca aaccaagtct tgcctttgat
     9961 accatggaat aaagagtggc tctttgtcaa gtgtagtggg tagtcgaaaa gctgcaatct
    10021 ggagagtacg aaattcgtac tctctttttt gatgttcaaa gtcatcaaaa tccgtttttt
    10081 aaaattgtta aagttccgga aaccaaaggc tttgcgcttg ataatcttaa tcaaattatt
    10141 ggtcgcttca agtttagcgt tggaataagg cagcttaagt gcgttgataa tcttatctct
    10201 atcccttaaa aaagtccaaa agaccgtttg aaaaagcgga tgaaccgttg gcagttcttg
    10261 ctcaatcaat ccaaagaaat ggtcggcatt cttctcttga aaatgaaaga gcaggagttg
    10321 atagagttcg tagtgaacct gtaatccctc agagtaagaa agcagcttat ctcgtacttc
    10381 ccgatgggtt aagtgcattc gaaacgtggg ctgatagaat cgtttctgac agagcttgaa
    10441 gctatactgg tgtagtaaat cagtccagtg gactgattta gcccgagcct agaaacgaaa
    10501 aagcgagggt tccaaaagcg cttgagcgcc cgatactcca aggattttcg gtcaaattgg
    10561 ttcatgattt ggattcgtac tcggttcata gctcggctca gatgttggac aatgtggaag
    10621 cggtcaagaa caatcttcgc ctttggaaag agttgcttag cgagccgata ataagggctg
    10681 tacatgtcca tggtgatgac ctcgaccagc tcccgaacct ctctctgata gcgttggaaa
    10741 tggtttcgaa tcaccgcatg agttcgcccg tctaaaattg cgaggatgga tttggactca
    10801 aaatcttggg caatgaagct cattttgctc tttttgaagc tatactcatc ccaactcata
    10861 acttttggca acttggtcca atcggtttca aacttaaatt ccctcagttt tcggatgacg
    10921 gtggaagttg agaccgccaa tctgtgggca atctcagtca tagactgctt ttcaaggagg
    10981 agctgagcga ttttttgtct caccatgttg gaaatctggc aatttttctt gacaatggat
    11041 gtttgagaaa cgaccacctt aaggcaattc ttgcactgaa agcggcgctt tttgagatgc
    11101 agtaccgtgg gtaaaccctg acagtcgaga agcggaattt tagaggcttt ctggaagtcg
    11161 tatttgatca tcttcccttg acaatgagga caaggaggag cgggggaatc caactttgcc
    11221 tgaacgacta gatgggtttg gtatttcaga acagacaaga ttttgatatt tttgtcttcc
    11281 aatccgagca aatctgtggt attcttaagt tgttccatat ggaccctttc taatgagttg
    11341 gttagacgct tttcattata ggtcatatgg ggcttttttt ctacaagaaa cgaccctata
    11401 attcctgggg tgggattacc cactacagaa attatagagc caaagcattc caaagtcttg
    11461 tctgactctg gaatgttttc tgttcacagt tgttttgtaa ctgcctaata agtaaccgcg
    11521 ctataacgag gtatctaccg agattgtcaa ttctccagta tactgttata aaaaacaaaa
    11581 ctggaggatt tttttatgtc ctcccatcgt cccatcgact gttccgtagc tgcccaataa
    11641 cggagtatag tcggctgaaa caagaatagg acaaaagtgc ctcaagaaaa gcatcgtaat
    11701 ttgacaatat tattctgaga tgtttttgat gtaagcccat attttctcaa tgggattata
    11761 ctcgggtgaa taggtaggaa gtggtaacag tctatgccct gctccttaca catgttcatt
    11821 ctgtgaaacc ttgcattgtc cataatgata agggatggtg tatctaaagt aggtagtaag
    11881 aatttttgga agcaagcttc gaaaaagtca ctcgtcatcg tatctttata ggtcatcgga
    11941 gccatagtat attgaaacaa aaaagggcat tagtacttct ataacagtat cgcaatctct
    12001 ggtgtgcgtt gtctcgatct taattcaaat aattatatct tcttccagag agactaactg
    12061 cctgctcaag gctcgatcat atttgagata aaaataggtc tcaacccctg tctcataaat
    12121 ataaatagga gtcaggtagc ttaagtgatt caattcttta aggaaccgat ttactttttc
    12181 tgggtcttgt tcgcagtagg tacggctctt tttagactat atcccatagc ctttagagcg
    12241 taatgaatag ttgttggagg acagttgaat tcagcagcta tttcagtcaa ataagcatcg
    12301 ggatgagttt caatatagat ctttaattta tctctatcaa ctttttcaat taatagtgga
    12361 agttttctta aagttagtgt gttgaaacgt ttttatacag tgctaaaatt tgaagtgtag
    12421 tgcagatgta tttgtaatag tattatagca attctttgga gaaggtcgag acaagagaaa
    12481 ataggtatct ttgagatata agtatgattt actataaaat tattgagtta ttcataaaaa
    12541 tttctctatc aaatatcata atgcgtcgtt taaggagatg gttacaatgc aatatagttg
    12601 tggaaaaata aatattaata tccctgatgg atatggagac attaaggata tagtgttttc
    12661 ggctcatatt atagttaggt ataataatgg acattgtgga ggtatagatc cgcatataat
    12721 tggactttgt aaaaagcaga tcagaaggat gtctccatat cctattttga taatcgtatc
    12781 tagagattca aaggttattg atgattataa aaatttagat attgcctatg ttgattgtac
    12841 tcaatgttca aataattttg aaactgcctt acacgttaaa aatattttaa aattattaaa
    12901 aatccaactt atacactgtc atggctactc aactaattat tttttatata tgttaaaaaa
    12961 acttgacaag aatggatttg gaaaggttaa gacagtgata acatgccatg gatgggttga
    13021 atataactta aaaaagaaat tcttgactta ttttgatttt tggacatatt ctatgggaga
    13081 tgcttttatt tgtgtatctg aaactatgaa aaaaagattg gagagtataa taaaaaaata
    13141 agaagatagt tgcaataaat aacggaatta atgtatcaaa tagcgattta gatgtagtag
    13201 gtgttcaaga ctttaaaaaa gaattttgta ttccaaataa caaaaaaatc atttgttatg
    13261 ttggaaggtt ggatccagaa aaaaggccgg atagattcct tgaatttgca gaaaaattat
    13321 ttttagtcag agaagatgtg atttttatta tggctggaaa tggtagtatg tgggctactt
    13381 tgaaagaaaa aatttgccat ttgaaatgta gagataattt caggttactt ggtgaaatct
    13441 atccagctac tatagtttac caaatatcgg atttattgta tattccttct gatacagaag
    13501 gaatacctat gtgtgtttta gagtcaatgt cacaagaaac tccggtttta gctagtaatg
    13561 ttggcgggtt aagtgaaatt attgaacata gggttgatgg atttttattt gagaaggaag
    13621 atgttgaggg agtgtgtgct tgtgctaatt ttttactcaa tgattctgag tatttgaaat
    13681 atataggtga gaatagtaaa tcaaaaataa gaaaacattt ttctgtgcaa aaaatgtttg
    13741 tagaaaccat gagagtatat gatgaattat tagagaagag tagtcatgga taggaatata
    13801 gatcaagaat tagtaagtat tataatacca acacataata ggtatgaatc tctgattaga
    13861 gctgtgaaaa gttgtttaca tcaaagttat aaaaatatcg aagttataat tattgatgat
    13921 aattatagta atgtaaattt aagaaataaa attatccatc aatttggcta taccagtcat
    13981 agaattaagt taattttaag taatgaagat ttaggtgcaa ctaatgccag aaacataggt
    14041 atcaaaaatt ctagaggtaa gtatatatca tttttagacg atgatgatga atatatgcca
    14101 gatcgaattt taaagttgat ggcttgtttt aaaaagagta gaatgaagaa tttagcttta
    14161 gtttatagtt atggaataat aatttatcca ataggaaata ttttaattta ttgagtttca
    14221 acgagagaat attggttaca aagaaatatt attctttaaa cataaagcgg ttactattaa
    14281 taggagacaa atgcaaggct ttaaaagtaa tcaagaaggc aagagaagaa aaaattttta
    14341 acgaatttct ttttcgaaat atatgttatt atatcatttt ggttttttct attgtatata
    14401 tgacaactat gttcaattaa aatttagaaa gtgagaaact attgtgtata ctattataaa
    14461 atcaaatata aaaaaattta gtttattaac gatatttatt gttgctggtc aattattgct
    14521 aatttatgca gcaactatta atgctctggt gttgaatgaa ttaattgcga tgaatttaga
    14581 gcggtttttg aaattgtcaa tctaccaaat gattgtctgg tgtgggataa tattccttga
    14641 ctgggtagtg aaaaattatc aggttgaagt gatccaagag tttaatctag agattcgaaa
    14701 tagagttgcc acagacatct ctaactctac ctatcaagaa tttcatagta aatcatcagg
    14761 aacatatctt tcgtggctaa ataatgatgt tcagacttta aatgatcagg cttttaaaca
    14821 acttttttta gtaataaaag gaatttctgg tactatattt gcagttgtga ctcttaatca
    14881 ctatcattgg tcattgactg tagccacctt gttttcatta atgattatgc tacttgtacc
    14941 aaaaatcttt gcatcgaaaa tgcgagaagt tagtctaaat ttaactaacc aaaatgaagc
    15001 ttttttaaaa tctagtgaga ctatattgaa tggatttgat gtgttagcgt ccttgaatct
    15061 tttatatgta ttgcctaaga aaattaaaga agcaggaatt ttattaaaga tggttataca
    15121 aagaaagaca actgtagaaa cgttagcagg cgctattagc ttctttctca atattttttt
    15181 tcagatatct ctcgtttttt taacaggcta tcttgcaata aaaggaatag tgaaaattgg
    15241 tactattgaa gcaataggag cactaacagg tgttattttt acagcgctag gtgaattagg
    15301 aggtcaatta tcctctatta ttggtacgaa gcctattttt ttaaaattgt attcaattaa
    15361 tccaattgag tcaaataaaa tgaatgatat cgaaccaaat gaggtgaata gagattttcc
    15421 gttatatgaa gcaaaaaata tttgctataa gtatggagat aaagaaatat taaaaaactt
    15481 aaatttttgt tttcaacgta atgaaaagta tttaatttta ggtgaaagtg gaagcgggaa
    15541 atctacatta ttaaaattat tgagtggctt tttgagagat tatagtggag aattgcgatt
    15601 ctgcggggat gatataaaaa aaacctccta tttaaatatg gtttcgaatg ttctatatgt
    15661 agatcaaaaa gcttatttgt ttgaaggtac gattagagat aatattttat tggaagaaaa
    15721 ttatactgat gaagaaatac tacagtcttt agagcaagtt ggtttgagtg taaaagattt
    15781 tcctaataac attttagatt attatgttgg tgatgatggg agattactgt caggagggca
    15841 gaaacaaaaa attactttag ctagagggct aattagaaat aagaaaatag tattaattga
    15901 cgagggaact tctgctatcg ataggagaac ttcgttagcg attgaacgta agatattaga
    15961 tagagaggat ttgactgtca ttattgttac ccatgctccg catccggaac ttaaacaata
    16021 ttttactaag atatatcaat ttccaaagga ttttatttaa gaatataggg gagggaaaca
    16081 tgagattcta ttgtgaagct tatgaggtaa ttactgaaga gaaaaaagta tactttaatg
    16141 atattgagtt agaagttaag tattcctctg tcgaagaatt gtttataata tgtgagaaat
    16201 tattagataa gaaaaaagta tcattttttt atgtatatga gaaaccctta aggtatctgt
    16261 tatttgacta tatatttcta ctagttctag ctaaaaaaaa tatcccaatc ttagatggag
    16321 tttccaataa gcaagttgat ccaacgttgc tgcatcactt ttctttggaa attgaaaaga
    16381 attttatcga tttttgctat aaaaatatgg atctcatcct aaaaactcaa agtatatctt
    16441 tgtgtcatag agaagagctt attattgtag atgtttcaga tgactctaaa tttggtgttt
    16501 tttacaagcg ttttagaaca ctggttgata aaaataacgg aaaatatgtt tgtgtttata
    16561 atttcagtcg tgtttcagat atactgcaaa actggaaaaa ttattgcaat cgaaaatttt
    16621 cggttacgtt tactgaaagc caatttgaat tatttaagct tttatataat caaaaaaatt
    16681 ttaaaacaat ttcgttgcta tttggaaaaa aattgttgct ggaggaatta tctattatag
    16741 cgatcttact aatatagaat acttttgtat tttttggtgg gatagtatgt ttgggaaaga
    16801 ttctattgga aaatacgtat atgtagaaga gattagtaga tgtcattttt tagatagaaa
    16861 ttattctttt tgttatggtt tacaagatta taaaagtaaa cttattaaat attttttaga
    16921 atagttaatc tattcgagag agataaagaa atatggaaaa tactttattg aatatcacag
    16981 gaagcttcga tatggaaact aggaatctaa ttagttattc tttaactgat atctttgaaa
    17041 cagataaaat aagaattgaa cttcttggag aaatttatta taaaaatata aagttggaat
    17101 tgcatgaatt cgctggattg tataagattt atggaattag cttaataaag aatattaccg
    17161 gaatgttttt aattataatt tttgatacga agacaaaaga attaaaaatt tttcaagata
    17221 taacgacttc atactttaat ttatactata ctgtttatgg aggtgtgttc tatatatagt
    17281 acatctttaa agaaagtgat gaagttatct catgttcccg ttaccttaaa taacaaaaaa
    17341 atacaagaat ttatgagaaa tggatttatt ttagattcaa atactttagt aaccgaaatt
    17401 aataaattag aatatttctc ttacatttct gtaaataata ctcttcgtat atgtggtatt
    17461 gattataatg attcaaacaa ttttactaaa gaacaagtat taaagaattg ggactctatg
    17521 ctacgtgaat ctatattaag agtgtatagt gaagcaggag aggctaatat tacactatca
    17581 tctggttttg attcaaatta tatattatat acattagcga attatacgaa ttcttcaatt
    17641 aatgcatttt gcataggagg agaaaaagga attaatgaga ttcctgaagt aactaaaatt
    17701 gcaaaatttt atggtataaa tttattagtt gatactgtaa tgagcccaag atttagaata
    17761 ttttcccgat atagtatgga gattggaagg aagtctcttt gaatgtggtg tcatactgca
    17821 gtactattta ggcaggttgt tgttccaaaa agggaacaca agtattcttt gtggcgagtc
    17881 agcggatgaa ataatgactt ttaagtatca ttctgtgaac tacaatcaat tttgtaatga
    17941 taaacagaag tcagtatatt ttagttattc cgactatcca ttttatgtta caaattcaat
    18001 tgttttaaag aaaaatagcc tacttttgca tagttttggc attcatccta gatatccata
    18061 taaaatgtct gagattgttg aaatgtctaa aaaaatatca gatctaaacg ataaaaaaga
    18121 atttcacaaa aagaactgtg agttgaggtt tcaagatagt gttcttgata acataaatag
    18181 tgtcccgggt acaactcatt tatttagttg tttaaatatt caaacattag taaaaattat
    18241 tttatatatt tttcgataca acagttgtat gaaaatattt aattttagag ataaagagct
    18301 tatctttttt aataagattg taaatgggct gatacaaaat attgaggaga atttagagga
    18361 tgatattgaa aggatattga aatatttata tatatgttta tttaacgaaa tattcattat
    18421 taagaataag gtgaattttt ttgatgatgt ggaatttaat cagacactta gtgagttttt
    18481 agataaattg tagagggaat ggttatgagt gacaatacta agtatatctt tttatctcca
    18541 catttagatg acgcaatttt ttcctgtggt gattatattt caaaattaac ttcagaagga
    18601 gaaattgtac ttgttattac tatattttct ggttaccctt tgagccaaca gctacagccc
    18661 tctgctaagc aatttcataa gttgtgtaac cttgggaaat atccgattga agaaaggaag
    18721 aaagaagaca ggttagcttg tgaacgtcta caatgtgatt ttagacactt atcgtactat
    18781 gaatgtctct ataggaaaga tagaaatggc aattttctat accgtcatat ctatagtaaa
    18841 ttaaaaaatg aggacacatt aaagaatgat atcataaaag agctgttaat gcatttagac
    18901 gacaaatgtg tcgtatattg tccgctttca cttggtgacc atgttgatca tgtttttgtg
    18961 aatagtattg gaagggcgct tgaatttatg cgttataaag taatatatta tgaggacttc
    19021 ccatatgtaa gtgatagtag tatggttagt tatatgggaa aaactaaaga attaaaaatg
    19081 tatcaagagg aacttgatga aaaacattat attgatagaa tatcatcaat attgtgctat
    19141 aaatctcaga ttttgataat ctggaaatca gttgaaaaac ttttaaacaa tattaaagag
    19201 ttgtatttaa ggaatggggc agcttattct attagatttt ggattaagaa ataaggaagt
    19261 agttttatga atatagcagt aattggtttg gggcatgttg ggctggccta cgcgttacta
    19321 tttgcatcta aatataaagt tgttgcatat gatatagatt ctgtaaaaat aaataattta
    19381 aaaaagggca ctcttccatc taaaaatgaa gagcttatga agtttttttg cgagaataac
    19441 ttaaatatta ctttttttga tacattttct gaaattaaaa ataatattga ttattatatt
    19501 attgcgcttc cgacagatta tgatgagaaa attggtagtt ttaatacata tgaaatcgaa
    19561 caaacggtat cgaagattct gagggtaaaa cctaatggaa agattatttt aaagtcaaca
    19621 gttccgatcg gcttttcaaa caaattaaaa aggctgtttg atacaaaaaa tatcattttt
    19681 gtccctgaat ttttgagaga aggttgttct atatatgata atttatatcc aagtcgcata
    19741 gttgttggag atgagacagt tgaaggaaga aaaattgcag agttgttcct ttcgattagt
    19801 actcatagta ctgccaatat taaaaatgtt atgttagttt ctcctactga agcagaagca
    19861 attaagcttt tttctaacac attcttagct ctccgtgttg ctttttttaa tgaactagat
    19921 tcttttgctg agaggagaag tttaaatgct gaagttgtaa taaaaggtgt ttgtttagat
    19981 ccaagaattg gaaattttta taataatcct tcttttggat ttggaggata ttgtcttccc
    20041 aaagatacta gacaattaaa aaaagaattt atagaaataa atgccccagt gatagaagcg
    20101 attgatattt caaacacaaa tagaaaacag ttcatagtta aacaaatatt ggaacgaaag
    20161 ccaaagatag taggaatata taaattgggg atgaaatata attcagataa ttacaaagag
    20221 tcagctattt taagtataat taatgaacta ttgattgtcg gtataaaaat tttagtatat
    20281 gaaccaaatt taaacgttag tatagataac gtaatttttg aaaagaattt tgaactattt
    20341 ataaaacaaa gtgatctaat tgttgcaaat agatgggata ggggccttga agcttataaa
    20401 gataaagttt acacaagggg gatctggata agagattaac tattgatatt aaaaaggcaa
    20461 taatttataa aatttgtaca aaaaaatgtt aaattttcac attttcatag tatactgttt
    20521 aatagaaagt aggttctttg taaccgctcc attataaaat cctttcactc ttccggtata
    20581 ctattaggaa aaacataact ggaggatatt ttgagctcac acctcatcgt tccagtggct
    20641 gttccccaag ctcgtgtact gcccaaaaaa gttagacatt ctatttagaa cgaggattga
    20701 gttctgtatt gtacaaggct cggtcctttt agagtcagct taaggctggc tttttcaatc
    20761 accaaagtgt cagaatgttt tgacaaatga acacaaataa tgatataata tgcaaaagct
    20821 aggaggtggt aggatgattg aaaaaatgga actgggggaa ttttacaagg aattgcgctt
    20881 ggcgagaaag ctcaagcagt cagatgtggc ttgtgctgga ctaacagcct ctcagttgtc
    20941 caagtttgaa ctaggacagt ctatgctgtc tgcagacaag ctgatcctag ccatccaagg
    21001 gatcaatatg aattttgatg agtttgggca caaactcaac aactatcaag aatctccaca
    21061 tatgcgaatt ggtagaaggg ttgtggattg cttttcccat caggatatag ctgctttaga
    21121 gcagctattg gaggaagtcg atcaagaaca gatggcgcag acctatcgtc gtttgaatgc
    21181 cattgtgatt aaaaatgcac tccattcctt agataaaagc tacccgctaa cagaggagga
    21241 tagcgagttt ttgactacct acctctacgc tattgagtct tggacctggt ttgaactcta
    21301 tcttttttgc aatactatgc ccttcttgag caatcaagat ctgatctttt tatcaacctc
    21361 cttactcgaa aaatccaagg aatttaaaga gttagtacac aatcgatggt atatgaaaag
    21421 tggttatctt aatatcatct cagaacttat ggagcgcaag ctattttctt atattccaat
    21481 ctttgaagct gagctggagc gcatgctccg tccatacgat gtttttgaaa aagtattgtg
    21541 gcagttttta aagaaaatgc agatttttct tcaaaccaaa ggaagcaatc aaaaagagat
    21601 tgaacacttt atccaatctc tgcaagtatt agaaaatcca caattgacag ccctttttga
    21661 attgcgtttg cagcaataca aagagcttat cgattagtta gaaatgggaa aaagataata
    21721 atatcagcaa cgatcgtcaa taatgttaaa acttgtttct tcatattact tccctcctca
    21781 ttagtaataa ctttattata ccagggaaat aatcaaatct accaaaatcg caaatctgaa
    21841 atttctataa gaaaaaatat caaatatgcg attttctaaa ataagccaat ttccgtgtta
    21901 tactgtcctt gtaaaacatt tgaagcaaat cctaggtcgc agaagtggtt tacaaatgaa
    21961 gataattgaa ggagtgtaaa agatgttaaa tttacaattt gcagaaacaa tggaattgac
    22021 agaagctgag ttgcaagatg ttagaggagg caacctcgta aattctatgg gaggtggtgg
    22081 aagaagtggt atatctggtt ggggcgtccc aggaatttac cctggttggg gcaatcaagg
    22141 gatgagtcct aatcgtggag cttttgattg gactatagat ttagcagatg gattgtttgg
    22201 ccgccgtaga agataggctc ttataggaga taataggatg aagaaaatga aagaagtgaa
    22261 atttcaccta gcaactggct tgttgatttt gacttattac ctcattttta atgtcacatc
    22321 agacttagat tttatggttg ctttgtctga taatatgtac tatgtgttcc aagttttatt
    22381 ggtacttatt ctgggaacta tagctacaat tgcttttgtc aaaagtgaac attggaaaga
    22441 gtgtggtcgt ttccagtttc gttggtctta cctgggtgtt ttccttcttt cttttttctt
    22501 attgttcgtg tgggcaaatc taacaaccta tatctttcct cgtacccaga atggaagtac
    22561 agtcgtagaa gtagccacca gtttaacagg aattagctat tttgttacgc gaatacttta
    22621 tactagtatt atcgcacctg tatcagaaga ggttgtttgt cgtggtcttt tgatgacaag
    22681 tttatctaaa gttaagagat actatcttga tgttcttgtt tccgctgcca tatttggcgc
    22741 tatgcatgtt ttgcagtatg gttggataac gacagatttc ataaagtatt ttggaatggg
    22801 cttgatattt tgtatgatgt ttcgctacac ccgatccatc tattgggcta tagctctgca
    22861 tgcttcatgg aatagcttct tactcattgt tactttattg gtatttggat attagaaagg
    22921 tgatatatga aaaagataat ctcacaccgc tactttatta tagtttttct actagttatt
    22981 gctgaccaga agttcagtgt tttagtttta cgcagcgacc ttgttgctgg gctatctgac
    23041 tttgcctatt atctgtcgga tatgatgttg aattttcttg tggttttatt tgctcttatt
    23101 gctatgattt ggtcggggaa atggcagaaa atcaatagta gaaagtttaa aggatcctat
    23161 cttttctatt ccttcctagc tctgcttgct tttgttgctt ggaattttgt cacctttttt
    23221 cttttcccac ctactcgaaa tgaaatttct tatcaacatg ctgctcctac ttttacagga
    23281 gctacggcat ttttgatgta ttttttttat cctgtgattg caggtcccat ttttgaagac
    23341 atgatttatc gtggattggt gatgacagct ctggaaaaag gaaagaaatg ggggctagat
    23401 gtacttggtt ctgctatttt atttggggtc tcgcacatta gtaatcacgg ttgggtcttg
    23461 acagactttt tcgtctatat gggtggcgga cttatatttg cagtcttatt tagaatgaca
    23521 aagtccattt attggcctat tgggctgcat atagtctaca acggcattgg tcagcttttg
    23581 atgttactgt aattttggtt gttagtagta tcgcggtcta tttctgggga aagattccca
    23641 tttgaactta agaaggagtt gtgatgaaag tatttcttca aaatagagat tttaggcaat
    23701 taactatcaa ccagtggatt tcaacgcttg gggatacgat tttttatctg gccttcctga
    23761 attatgtggc agatgcgtct tttgcccctt tggcgatttt acttatcacg atttcagaaa
    23821 cccttcccca agttctacaa atctttctgg gagttttggc ggattttcaa catcatcgtg
    23881 tcttgaaata cacagtcatt agttttacaa aatttttgct ttactctata gtgtccctat
    23941 cgctttcagg gcagtctttt tccttgttgc tagtaacctt tatttgtctg cttaacctct
    24001 tgtctgacac attgagttat ttttcaggcg ccatgctcac tccgattttc attagaatta
    24061 ttgggcaaga ccatctggca gaagctattg gatttaaaca gtcaactgtt agtttagtga
    24121 aaacaatcag taatatccta ggaggagtct tactaggcat tctatccatc cagtttattt
    24181 ccttactgaa cgctcttacc tttttaatcg catttttagg tatcctcttc ataaaaactg
    24241 acctcttgaa agtagaaaaa acgattagct atcaagaagg actctctgta aaatcctttt
    24301 gccagcattt gctccaatca tcgaaattga tatggaatat gaataaggtg ctcttggttt
    24361 tgtttattat ctctactagt caagcagtga taaatgttac ggttcctatt tccactctat
    24421 ttttaaggaa ccagcccttt ttgaatttac aaactggtca atctcttgcc ttgttagcca
    24481 cactagaatt atcagccctt attttgggaa gtctgatgag tggctatctg caacatacca
    24541 tttccataaa aatagccctg tatgcttcac tcctactcca attactactc ctagtgggct
    24601 ttgcgacagc tcattttggc ttgattctga tctttagctt tttggatgcc tttttcgcgg
    24661 gtattctctc tcctagattg caagaactcg tctttaaaca aatacctgag gagtcaatgg
    24721 gagcagttca atcttctatc ggtgccatta cggttgtttt acctagctta tttacaatag
    24781 ctttgggaac cattgctact agctttggaa ctctggcagt tagctttgtt ttattactat
    24841 ttcttctagt tgcctttgtc atgcttctga atattcgtga aagtatttag tggagaattt
    24901 ctataatata tgtttgagac tggattgcca gtctttttat gatggtcaaa atcaacagac
    24961 tttttctctt ttctgaatgt gttatagtag actgaatcta aaatagtacg aaataattgc
    25021 taaaacattt atagaaatta attttacttt cccaatcgat ttgttctcat cttatttcaa
    25081 tctgctatat aatagtccat gctgtggctg gattcttttc agcctactta tactcttcga
    25141 aactctcttc aaaccacgtc agcttcacct tgccgtaggt atggttactg acttcgtcag
    25201 ttctatccac aacctcaaaa cagtgttttg agctgacttc gtcagttcta tctgcaacct
    25261 caaaacaatg ttttgagcaa cctgcggcta gtttcctagt ttgctctttg attttcattg
    25321 agtattatta agacaatatg aggagaaaga tgaaagaaaa aggattttag gagggggcgc
    25381 aggcagccat gccaacggct cttggctatg tcagtatcgg cctggcctgt gggactatcg
    25441 gtgcgcccta tgtgacacct gttgagatgg gcttgatgag tctctttgtt tatgctggga
    25501 gtgcccagtt tgccatgttg gcactgattg tggttcaagc tcctgtggca gctattgcta
    25561 tgacggtttt tctaatcaac ttgcgtctct ttttgttgag tttacacgca tcgacttatt
    25621 tccgtcatac cagtctttgg tacaatatcg gtatgtctag tatcttgaca gatgagacct
    25681 atggcgtttt gatgggtgaa ttggcccata cagacaaggt aaatcctatg tggatgcacg
    25741 gaaacaatct taacagctat gtggcttggt ttgtggggac agtagtcgga acggctctgg
    25801 gtggcctgct accaaatcca gaaatctttg gcttggattt tgccctggtt gggatgttta
    25861 ttggtatttt tgcttcgcaa tttcagatta tgcaaagacg gattcctgtc cgcaatctgc
    25921 tcattatcct agcagttgtt gcggtgtcct tctttttgct cttgacagtg gtgtctcagt
    25981 cactagctgt tctgtttgcg acgctacttg gttgtagcat gggggtggtt ttagatggtc
    26041 agtaagtatc ttttattagc agttattttc tctgacttgg tgacttggat tctccgtatg
    26101 attcccttca tcttagtcaa gtataagggc ttgcctgcaa tcgttgagcg ttttttgaag
    26161 ttcttgcccg tttccattat ctttgccttg attctttcaa gcgtagtgac aggtaaggtt
    26221 gggagccttc ctcaaattaa atggctagac ttcttagccg tctttccaac agcttgggta
    26281 gcctttcgct accgcaatct agtcggaaca gttctctttg gagtagtctt gattgccgtc
    26341 ttgcgtttgg tcttttaaat cagccataaa gaaaacctat cacagatata tatatcatat
    26401 aatggtgtaa atgatttttt tctgttaaga ttataaggta ttctattttg gaggaaatga
    26461 catgaaaaaa atcgttaaat actcatctct tgctgcccta gggcttgttg ctgcaggtgt
    26521 gctagcagct tgctccggtg gtgctaagaa agaaggacaa gcagctagca agaaagaaat
    26581 tattgttgca actaattctt caccaaaacc attcaactat gaagaaaatg gcgaattgac
    26641 tggttacgag attgaagtcg ttcgcgctat ctttaaagac tctgataagt atgatgtcaa
    26701 gtttgagaag acagagtggt caggtgtctt tgcgggtctt gacgctgacc gttaccaaat
    26761 ggctgttaac aacatcagct acactaaaga acgtgcggag aaataccttt atgcagcccc
    26821 aactgttaaa gaccctaacg ttcttgtagt caagaaagac gattctagca tcaaatcgct
    26881 tgatgatgtt ggtggaaaat caacagaagt tgttcaagga acaacatctg ctaaacagtt
    26941 agaagactac aacaaacaac actcagataa tccaactatc cttaactata ctaaagcaaa
    27001 cttacaacaa atcatgggcc acttgagcga tggtcagttt gactacaaga tttctgataa
    27061 aatcactgtt gaaacagtca tcaagaacca aggtttggac aacttgaaag tcatcgatct
    27121 tccaagcgac caacaacctt acgtttaccc acttcttgct aaaggtcaag atgagttgaa
    27181 aacatttgta gacaaacgta tccaagaact ctacaaagac ggaactcttg aaaaattgtc
    27241 taaacaattc ttcggagaca cttacctacc ggcagaagct gatattaaat aatttcttga
    27301 aatcatccat tctgagtaag atgggtgatt tttcagttcg ctaccgcaat ctagtcggaa
    27361 cagttctctt tggagtggtc ttgattgcca tcttgcgttt ggtcttttaa attacccata
    27421 aaaaaaactt atcacagaga tagatatcat ataatggcgt aaatgctctt tttctgttaa
    27481 gattataagg tattctattt tggaggaaat gacatgaaaa aaatcgttaa atactcatct
    27541 cttgcagccc ttgctcttgt tgctgcaggt gtgcttgcgg cttgctcagg tggtgctaag
    27601 aaagaaggac aagcagctag caagaaagaa atcatcgttg caaccaatgg atcaccaaag
    27661 ccatttatct atgaagaaaa tggcgaattg actggttatg agattgaagt cgttcgcgct
    27721 atctttaaag attctgacaa atataatgtc aagtttgaaa agacagaatg gtcaggtgtc
    27781 tttgctggtc ttgatgctga ccgttacaat atggctgtca acaatcttag ctacactaaa
    27841 gaacgtgcgg agaaatacct ctatgccgca ccaattgccc aaaatcctaa tgtccttgta
    27901 gtgaagaaag atgactctag tatcaagtct ctcgatgata tcggtggaaa atcgacggaa
    27961 gtcgttcaag ccactacatc agctaagcag ttagaagcat acaacgctga acacacggac
    28021 aacccaacta tccttaacta tactaaggca gatttccaac aaatcatggt acgtttgagc
    28081 gatggacaat ttgactacaa gatttttgat aaaatcggtg ttgaaacagt gatcaagaac
    28141 caaggtttgg acaacttgaa agttatcgaa cttccaagcg accaacaacc gtacgtttac
    28201 ccacttcttg ctcagggtca agatgagttg aaatcatttg tagacaaacg cattaaagaa
    28261 ctctacaaag acggaacgct tgaaaaattg tctaaacaat tcttcggaga cacttatcta
    28321 ccggcagaag ctgatattaa ataatttctt gaaatcatcc attctgagta agatgggtgg
    28381 tttctcagtt tttagggata tagttttaaa ctatatatct gactatctaa taacaatttg
    28441 tgaaatcaaa caaattgtga gatactagta cggtattatt tttaaggaga aagaatcatg
    28501 aaaatcaaaa aatggcttgg cctagcagcc cttgctacag tcgcaggttt ggctcttgca
    28561 gcttgcggaa actcagaaaa gaaagcagac aatgcaacaa cgatcaaaat cgcaactgtt
    28621 aaccgtagcg gttctgaaga aaaacgttgg gacaaaatcc aagaattggt taaaaaagac
    28681 ggaattacct tggaatttac agagttcaca gactactcac aaccaaacaa agcaactgct
    28741 gatggcgaag tagatttgaa cgctttccaa cactataact tcttgaacaa ctggaacaaa
    28801 gaaaacggaa aagaccttgt agcgattgca gatacttaca tctctccaat ccgcctttac
    28861 tcaggtttga atggaagtgc caacaagtac actaaagtag aagacatccc agcaaacgga
    28921 gaaatcgctg taccgaatga cgctacaaac gaaagccgtg cgctttactt gcttcaatca
    28981 gctggcttga ttaaattgga tgtttctgga actgctcttg caacagttgc caacatcaaa
    29041 gaaaatccaa agaacttgaa aatcactgaa ttggacgcta gccaaacagc tcgttcattg
    29101 tcatcagttg acgctgccgt tgtaaacaat accttcgtta cagaagcaaa attggactac
    29161 aagaaagcac ttttcaaaga acaagctgat gaaaactcaa aacaatggta caacatcatt
    29221 gttgcgaaaa aagattggga aacatcacct aaggctgatg ctatcaagaa agtaatcgca
    29281 gcttaccaca cagatgacgt gaaaaaagtt atcgaagaat catcagatgg tttggatcaa
    29341 ccagtttggt aataagaaac agggaggtgg gagagaaaat tccacctctt gcttttgtat
    29401 agagtataga ttgtaaagaa gactattcgt tcatagaaag gtagagagaa tatggttttt
    29461 cctagcgaac aagaacagat tgaaaaattt gaaaaggatc atgtagtcca acattatttt
    29521 gaggttttgc gtaccttgat ttctaagaaa tcagtctttg cccagcaggt tggactcaag
    29581 gaagtcgcaa attatctggg tgagattttc aagcgtgttg gagctgaagt ggagattgat
    29641 gagagctata cagcgccctt tgtcatggca catttcaaga gttcgcgtcc agatgccaag
    29701 accttgattt tctataacca ctatgacact gtgccagcgg atggggatca ggtctggaca
    29761 gaggatcctt ttacgctttc ggtccgcaat ggcttcatgt atgggcgtgg ggttgatgac
    29821 gacaagggtc atatcacagc tcgcttgagt gctttgagaa aatatatgca gcaccatgat
    29881 gatttacctg tcaatatcag ctttatcatg gagggagcgg aggaatcggc ttcaacagac
    29941 ctagataagt atttggaaaa gcatgcagac aaactccgtg gggcggattt gttggtctgg
    30001 gaacaaggga ccaaaaatgc cttggaacag ctggaaattt ctggtggcaa taaggggatt
    30061 gtgacctttg atgccaaggt aaaaagcgct gatgtggata tccactcgag ttatggtggt
    30121 gttgtggaat cagctccttg gtatctcctc caagccttac agtctcttcg tgctgcggat
    30181 ggccgtatct tggttgaagg cttgtacgaa gaagtacaag agcccaatga acgagaaatg
    30241 gccttgctag aaacttatgg tcaacgaaac ccagaggaag ttagtcggat ttatggattg
    30301 gagttgcctc tcttacagga ggagcggatg gcctttctaa aacgtttctt tttcgagcca
    30361 gcgcttaata tcgaaggaat ccagtctggt tatcaaggtc agggtgttaa gactatttta
    30421 cctgcagaag ccagtgccaa gctagaggtt cgtctggttc cgggcctaga accgcatgat
    30481 gttctggaaa aaattcggaa acaactagac aaaaatggct ttgataaggt agaattatac
    30541 tataccttgg gagagatgag ctatcgaagc gatatgagcg caccagccat tctcaatgtg
    30601 atcgagttgg ccaagaaatt ctatccacag ggcgtttcag tcttgccgac gacagcgggg
    30661 acaggaccta tgcatacggt ctttgatgcc ctagaggtac caatggttgc atttggtcta
    30721 ggaaatgcca atagccgaga ccacggtgga gatgaaaatg tgcgaatcgc tgattattac
    30781 acccatatcg aattagtaga ggagctgatt agaagctatg agtagagata ttatcaagtt
    30841 agatcagatc gatgtgactt ttcaccaaaa gaagagaacc atcacagcgg ttaaggatgt
    30901 gaccattcac atccaagaag gggatatcta cggaatcgtt ggatattctg gagcagggaa
    30961 atcaaccctt gtacgggtga ttaacctctt gcaaaaacca tctgcaggga aaattaccat
    31021 tgacgacgat gtgatttttg atggtaaggt caccttgacg gcagagcagt tgcgtcgtaa
    31081 acgtcaagat atcgggatga ttttccagca ttttaacctg atgagccaaa agacagcaga
    31141 ggagaatgta gcctttgccc ttaaacactc tggactcagc aaggaagaaa agaaggctaa
    31201 agtagctaag ttgttggact tggttggttt ggcagatcgt gctgaaaact acccttcaca
    31261 actatctgga gggcaaaaac agcgtgtggc aattgcgcgt gccttggcca atgatccaaa
    31321 aatcttgatt tcagacgagt caacttctgc ccttgatccg aagacaacca agcagatttt
    31381 ggccttgttg caagatttga accaaaaatt aggcttgact gttgtcttga ttacgcatga
    31441 aatgcagatt gtcaaagaca ttgccaaccg tgttgcagtt atgcaggatg ggcatttgat
    31501 tgaagagggt agtgtgcttg aaatcttctc aaatcctaaa caacctttga ctcaagactt
    31561 tatctcaaca gctacaggta ttgacgaagc catggtcaaa atcgagaagc aagaaatcgt
    31621 ggaacacttg tctgaaaaca gtctcttggt gcaactcaag tacgctggag cttcaacaga
    31681 cgagccactt ttgaatgaat tgtacaagca ttaccaagta atggctaata ttctctatgg
    31741 gaatatcgaa attctcgatg gtactcctgt tggagaattg gtggtggtct tgtcaggtga
    31801 aaaagcagcg ttggcaggtg cccaagaagc cattcgtcaa gcaggtgtac aactaaaagt
    31861 attgaaggga ggacagtaag atggaatcat tgattcaaac ctatttacca aatgtctata
    31921 aaatgggttg ggctggtcag gcaggctggg gaacggctat ctacttaact ctttatatga
    31981 cagttctttc cttcattatc ggaggcttct tggggctagt ggcaggtctc tttctcgtct
    32041 tgacagcgcc aggtggtgtc ttggagaata aagtcgtatt ctggatttta gacaaaatta
    32101 cctcaatttt tcgtgcagtt ccctttatca tcctcttggc aatcttgtca ccactttctc
    32161 acttgattgt taaaacaagt atcgggccaa atgcagccct tgtcccactt tcttttgcag
    32221 tctttgcctt ctttgcccgt caggtgcagg ttgtcttggc tgaattggat ggcggtgtca
    32281 ttgaggcggc tcaagcgagc ggagcgactt tctgggacat cgtgggtgtt tacctatcag
    32341 aaggtcttcc agatttgatc cgtgtgacga ctgtgacctt gatttccctt gttggggaaa
    32401 cagctatggc cggtgcggtt ggagctggtg gtatcggtaa cgtagccatc gcttatggat
    32461 ttaaccgcta caatcacgat gtgaccatct tggcaaccat cattatcatt ttgattatct
    32521 ttgcaatcca attcttggga gatttcttga ctaagaaatt gagccataaa taaaaaagag
    32581 ccgcgtggct ctttttaact gatcagattt tctgtgcaaa ttttttactc aaggcttgtc
    32641 caatcaaggc acccactagg gctccgatga caatacttgc gataaataga aggacagttc
    32701 cagggtttgg agcgaccatg atgcggtcga tatattcttg ggattttcct cttgccagaa
    32761 gagtagccat ataggctttg ggcgcaatcc acataagcaa gattggtcct gttgtactaa
    32821 aggcgaaaat aatgaaagaa aggaagttct ttgttttgtc cttgtatttt cctaaatgag
    32881 ctactccatc tgctaggagg ccacagataa ttccaggaag gaaggaacca gcaccgtgtt
    32941 tagttcccaa gaaaaagagg gcaatgacaa ggccgatagt ggtaatggct ccaaagcgcg
    33001 gaacttttgc gactaggatc atatagacgc taccgccgac aagggcagta aaggcaggcg
    33061 cataaaacat gtttccagtt tggtcaaaga gattgcccaa aaggacacca atccccatgc
    33121 agaggaagta aagaactgca aaaagcagtg tagttaagat agatttcttc atgaattgtc
    33181 tcctgataat tttttcacaa ttctcatttt accatggttt ggtgggattg taaatggata
    33241 ctagaagttt ttgaaaacgc ttgaaatatg atataatggt ttcatagtta tttttagggg
    33301 aatatcatgg gtagattttt agactttgtc tttaatcgtt tctttttagg gatgattgcg
    33361 acagccttct tttggctatt aactttagca ggagggatta tccttggtct agcgccggct
    33421 agtgccacct tgatgagctt atatgcagaa catggttata gctttcggga atacagtttg
    33481 aaggaggctt ggtctcttta caagcaaaat tttgtctcaa gcaacctgat tttctatagc
    33541 tttttaggtg tgggtctagt tttgacctat ggtttgtatc tcttggtgca attgcctcat
    33601 cagactattg ttcatttgat tgcgaccctt ttgaatgtcc tagtagttgc cctgatcttt
    33661 ttggcttata cagtatcttt aaaattacaa gtttattttg ccttgtccta tcgaaatagt
    33721 ctcaaattat ccttgattgg catctttatg agtctagcag ctgtggccaa ggttctcctt
    33781 gggactgtgc tacttgtagc aattggttac tatatgcctg ccctgctatt ttttgtagga
    33841 attgggatgt ggcatttctt tatcagtgat atgttggaac ctgtctatga aatcatccat
    33901 gaaaaattgg cgacaaaata gaatgaagca gttttggcta catacgcttc taagaaccta
    33961 tagttcagtg atgatcatta tcattgcgag ttttgcaatc ttactctctt acgctgactg
    34021 ggattcacgt gaaaaggaag cccagagagt agcccagcgt gtaactgcta gaacagtgag
    34081 tgaaattgaa tattaccata gagagtcaac ccagatagct caggctttag ttgaaaatca
    34141 agctcgtatt gagggaatct ataaatactt tagccttagc atgccagact atttttactg
    34201 gcaattagag cggaaagctt cgccttatat atcagtctct ctgtatgaaa atgttgatga
    34261 cctctatgtt cgaaatgatt ttgtaactgg ggtggccatt gcttttcaag attacaagga
    34321 agtctatgtt tctactaaag acaaacgtag tggagaaaaa atcagggctg aggatttcaa
    34381 accagcagga aatagttttg ccattccggt gtcagatcca gtgtcagatc aagatttagg
    34441 agtgatttac atctccttgg atcctgctgt tttataccat gccattgata atactagagg
    34501 tcatactccg atggcagtaa cagtgacctc accttttgat acggagattt ttcatattgg
    34561 tgagacagtt gatagggaga gtgaaaattg gctagttggc ttaacttctc atggatatca
    34621 ggttcaggtg gcagttccta aaaactttgt tttacaagga acagtgacta gctctgcttt
    34681 gattgtgggt ttgagccttc tctttattgt cattctttat ctgactttga ggcagacttt
    34741 tgctaattac caaaagcagg tagtggattt agtggaatcc attcaagtca ttgctcaagg
    34801 cgaagagggg cgtcggattg acatttccga aaaagatcag gaattactcc taatcgcgga
    34861 gacgaccaat gatatgttgg atcgattgga aaagaatatc catgatattt accagttaga
    34921 gcttagtcaa aaagatgcca atatgcgagc cttgcaggcg caaatcaatc ctcattttat
    34981 gtataatacg ctggagttct tgcgcatgta tgcagttatg cagagtcaag atgagttggc
    35041 agatatcatt tatgaattca gtagtctctt gcgtaacaat atttccgacg aaagagagac
    35101 cctcctcaaa caggaattag aattttgccg taaatacagc tatctctgca tggttcgcta
    35161 tcccaagtcc attgcctatg gtttcaagat agatccagag ttagagaata tgaagattcc
    35221 caagtttacc ttgcaaccgc tggtagaaaa ctatttcgcg catggtgttg accacaggcg
    35281 gacagataat gtgattagca tcaaggctct taaacaggat ggttttgtgg aaattttggt
    35341 ggtcgataat ggtagaggaa tgtcggctga aaagttggca aatatccgag aaaaattaag
    35401 tcagaaatat tttgaacacc gagccagcta cagtgatcaa aggcagtcta tcgggattgt
    35461 caatgtacac gagcgttttg tgctctattt tggagaccgc tatgccatta cgatagagtc
    35521 tgcagagcaa gccggtgttc agtatcgtat tacaattcaa gatgagtaga aagggagaaa
    35581 atgtataaag tattattagt agatgatgag tacatggtga cagaaggtct gaagcgtttg
    35641 attccctttg ataagtggga tatggaggtc gtcgcaacag ccagtcatgc cgatgaagct
    35701 ctagaatatg ttcaggaaaa tcctgtcgat gtcatcattt ccgatgtcaa tatgccagac
    35761 aaaacagggc ttgatatgat tcgggagatg aaagagatct taccagatgc tgcctatatc
    35821 ctgctctcag gttatcagga gtttgattat gtaaaaagag caatgaacct tagtgtggtg
    35881 gactatttgg tcaagcctgt tgataaggta gagctgggaa atctgctgga gaagattgca
    35941 ggtcagctcg gcgagagagg gaagaaaagt cagactctta gtcaagaatt agacgaggct
    36001 ggatttgtta gttatttagg ggataaggag aattggtgga taggtctatc caaggaaaaa
    36061 caaggttcct tcaccattcc ctactatgtc ttgggccaag actggcagat tttcatttct
    36121 gaccaacccc tagatggttt agtcgttaca ccttttgaag ctccttatca agaacacttt
    36181 gaacgctgga agctgaatgc tgagaaaacc ctcttttacg gttctgtaaa tttgcagcag
    36241 tctgagagtc tctttgccta ttacgaaccg atttataggg ttatcattca gggaaatctc
    36301 aatcaaatcg tagaagagtt aaatctcttg gagaaggtag ttcttgaaaa tacgccgcgt
    36361 gttccgatta ctaaacagct ttttattcag tttgtcatgg atgttttcca tttatttgaa
    36421 catctcaaag ctgatgacct gacagacatc gtcaaaacca ttcatgctat tcaatccttc
    36481 gatgaattgg ttccttatat caaggaaact ctgagcagct ttttcggtca ataccgtatg
    36541 aatgaaaatg tggtcagtgt gctggaagtc attggttgtg attaccaaaa agagctttcc
    36601 ctcaaggata tcagtaaggc tctctttatc aatcctgtct atctagggca gttgattaag
    36661 cgtgaaaccg attcgacttt tgcagagtta ctaaacaaac aacgtattaa ggctgcccaa
    36721 caacttttgc tttcaactag tgacagcatc gaagatattt gttatgctgt tggttacagt
    36781 aaccttggat atttctataa agttttccga aaattgtgcg gaaaatcgcc aaaagcctac
    36841 cgaaaacagg tagaaactat actataagat ttgtattcct ttacaaaatg tgctataata
    36901 taaatattat tattaggagg ttctatcatg aaaaagaaac caatttatct atgggtcttg
    36961 ctaatcttgt ctgcccttat ttcagttccg tctctgtttg gaattgtgag tcccttgcct
    37021 agtaaagaag cccttcgtac tgctcagaaa caagttgcag gggtcaatgc tcagcaatta
    37081 gaagaccagc ttaattatac ctatagagta gcagaagcat ctcattctat ttttaatgtt
    37141 gctttgattg tgctatctac tattttagtg gtcgtagcga ttgtcttcct tgttcgtaaa
    37201 aatttgcaat atgcaaacta tacttacgtt ggctatgttt tgttagctat tattggttcg
    37261 atttatggct atgttggttt acaagacgct gtgcagttgg ttcaagatga gagcatgcgt
    37321 ttgacagtga gtattggttc aaaagctgtt agcattttct atatcgtcat caatgttctc
    37381 ttcctagccc ttgtcttcta taagatgtgg cgacaacaga aagcctcggc agaagaagag
    37441 gaaacagaag agcttgccta agtattgaca aaaaagaact atcaagatac aatcttggta
    37501 gttgtttttt gattatagat aaaatcatgg aggtacatat gaagataatt tctttagttt
    37561 atattagttt gagtggcaac actgaaagtt ttgtgacgcg cttgaaagac tatctcttgt
    37621 cccagtacaa agggattgag gttcaaaaga ttcatatcaa ggatttagtc aaggaaggca
    37681 aaaatttcta tgaaatggac catccctatg tcgctttttt gccgacctat ctcgaaggtg
    37741 ggaatggcgt ggataacgga gatgttgaga ttttgacgac accggtggga gattttattg
    37801 cctatggtaa caatgctagt aagtgttttg gtgtggttgg gtcaggaaat cgtaacttta
    37861 ataaccaata ctgcctaaca gccaagcaat acagtcaacg ctttggcttt cctgtattgg
    37921 ctgactttga aatgcgaggc atgctggaag atatcaaaca tgtcgcagct attatcgcag
    37981 atttgtatga gttggaaaag gagaattaat actcaatgaa aatcaaagag caaactagga
    38041 agctagtcgc aggttgctca aagcacagct ttgaggttgc agatagagct gacgtggttt
    38101 gaagagattc tcgaatagta taaaattctt ataagaggtg gttgaagttg ttcaactgtt
    38161 ttttgagtat aaacagtctt taagaacgta aaaaagcata agttcaggtc ttcaaaacct
    38221 tgttcttatg ctttttatca tagaaatatt tgctgaattt tctcttgaaa tgaaacctta
    38281 tcttcatctc gcgcttgtcc cttaccctgc ttttccgatt gcgagtgcgt agataaagaa
    38341 gatggcgaag ccaaagagga aaatcaatcc cgcaatggca aggtgtttga gccaagaagg
    38401 aagatttttg ttttcacgcg ttaccaaggc gtaattcaaa agagcaaaga aaggtgttgt
    38461 caggaaagag ccaatcatgg caaagcggag catggttgaa acctgaccag agaagaactt
    38521 gataatgacg ataccgatga tagcagtgat ggtcatccag atgttcaaag atttacgatt
    38581 gtcctctttt tgactgatta gcagtcggag agattcctga ttaacgcgag aatagccatc
    38641 gataacagtt ataactgttc caaagataca gaggaaggca ataaaggtaa tcaagtaacg
    38701 ggaccattcg ccaagaacag aggcatacat gcccacgaat tgagagatgt atttggctga
    38761 agcagcttca accgcctgcc ctgtaggata ctgaatcagt gctcccagtg ccacaaagaa
    38821 gacggctagg atagctgttc caatataacc agtgttaaag tcaaacagag cgtcttctgt
    38881 gttaaagttg acggtctttc tcttttcagc tgaccaaagt gaattgatgg ctgaaatttc
    38941 aataggagcc ggcatccatc ctaggaggga gacgatgaag ggcagagctg ccatttgcca
    39001 aggtgtcttc tcgacaaaat cagaactgta ttctggatgc ttgaccgccg caatgataac
    39061 tgccagaaca gtcgcaatgg ttaaggcaga cataatccat ttgaccatgc cgtctaaaag
    39121 tttgtagcct ccaaagagta gcatagccca aatgattgca acgagaatga gggaccactg
    39181 agtaatgcta agtccaatca ttgggaaggc actggcgatg atagctgagc acagaatggc
    39241 aacaccagcc gtgttgacca tagccgaaaa gacattgagg ataaagaaaa tccagagata
    39301 gagttttcct ttttcggcat aaccttcaac caaagtcttt ccagtatcag ctgtgtattc
    39361 agcaccaaaa cggaaaaatg gatatttaaa gacattggct aagatgacca agagaagtag
    39421 agaccaaccg taagaaccgc cagcttgagt tgaggataca atgtgggaac ctccaacagc
    39481 ggcagttgcc attaggattc caggtcccat tgcttttagc ttgcttgccc aggttgattg
    39541 atttaaggaa atagcttgcg acatgataaa tactcctttt tgaattttca gaataatctg
    39601 tatatgtaat ctatattcta caaaaaattt tggaaaaatg caagaatatt ttgaaaaaag
    39661 atagaaaatt tacaaagaaa at
//
LOCUS       DAVBEO010000013        38565 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 009
            SAMEA1678075-rid20185393.denovo.013, whole genome shotgun sequence.
ACCESSION   DAVBEO010000013 DAVBEO010000000
VERSION     DAVBEO010000013.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678075
            Sequence Read Archive: ERR226392
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 38565)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 38565)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980207.1
            Genome Coverage       :: 150x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:50:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 72 of 147
            Pseudo Genes (incomplete)         :: 72 of 147
            Pseudo Genes (internal stop)      :: 42 of 147
            Pseudo Genes (multiple problems)  :: 32 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..38565
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678075-rid20185393.denovo.013"
                     /strain="KS 009"
                     /db_xref="taxon:1313"
     gene            complement(56..1066)
                     /locus_tag="VQ543_000728"
     CDS             complement(56..1066)
                     /locus_tag="VQ543_000728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YeiH family putative sulfate export transporter"
                     /protein_id="HET2611481.1"
                     /translation="MSFLSKNGAGILACLLISIVSWYLGGFFPVIGAPVFAIFIGMLL
                     HPFLSSYKQLDAGLTFSSKKLLQYAVVLLGFGLNISQVFAVGQSSLPVILSTISIALI
                     IAYLFQRFFALDTKLATLVGVGSSICGGSAIAATAPVIDAKEKEVAQAISVIFFFNVL
                     AALIFPTLGTWLHLSNEGFALFAGTAVNDTSSVTAAASAWDSLYQSNTLESATIVKLT
                     RTLAIIPITLFLSYWQSRQQENKQSLQLKKVFPLFILYFILASLLTTLLTSLGVSSSF
                     FTPLKELSKFLIVMAMSAIGLKTNLVAMVKSSGKSILLGAICWIAIILTTLGMQTLIG
                     IF"
     gene            1215..2384
                     /locus_tag="VQ543_000729"
     CDS             1215..2384
                     /locus_tag="VQ543_000729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HET2611482.1"
                     /translation="MDLTKRFNKQLDKIQVSLIRQFDQVISEIPGVLRLTLGEPDFTT
                     PDHVKEAAKRAIDQNQSYYTGMSGLLTLRQAASDFVKEKYQLDYAPENEILVTIGATE
                     ALSATLTAILEEGDKVLLPAPAYPGYEPIVNLVGAEIVEIDTTENGFVLTPEMLEKAI
                     LEQGDKLKAVILNYPANPTGITYSREQLEALAAVLRKYEIFVVCDEVYSELTYTGEAH
                     VSLGTMLRDQAIIINGLSKSHAMTGWRLGLIFAPAAFTAQLIKSHQYLVTAANTMAQH
                     AAVEALTAGKNDAEPMKKEYIQRRDYIIEKMTALGFEIIKPDGAFYIFAKIPAGYNQD
                     SFAFLKDFAQKKAVAFIPGAAFGRYGEGYVRLSYAASMETIKEAMKRLEEYMREA"
     gene            2381..3151
                     /gene="recO"
                     /locus_tag="VQ543_000730"
     CDS             2381..3151
                     /gene="recO"
                     /locus_tag="VQ543_000730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000616164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecO"
                     /protein_id="HET2611483.1"
                     /translation="MIQSITSQGLVLYNRNFREDDKLVKIFTEQVGKRMFFVKHAGQS
                     KLAPVIQPLVLARFLLRINDDGLSYIEDYHEVMTFPKINSDLFVMAYATYVAALADAS
                     LQDNQQDAPLFAFLQKTLELMEAGLDYQVLTNIFEIQILTRFGISLNFNECVFCHRVG
                     QAFDFSFKYGACLCPEHYHEDKRRCHLNPNIPYLLNQFQAIDFETLETISLKPGIKQE
                     LRQFMDQLYEEYVGIHLKSKKFIDSLADWGQLLKEEKK"
     gene            3148..4140
                     /gene="plsX"
                     /locus_tag="VQ543_000731"
     CDS             3148..4140
                     /gene="plsX"
                     /locus_tag="VQ543_000731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000717456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acyltransferase PlsX"
                     /protein_id="HET2611484.1"
                     /translation="MKKIAVDAMGGDYAPQAIVEGVNQALSDFSDIEVQLYGDEAKIK
                     QYLTATERVSIIHTDEKIDSDDEPTRAIRNKKNASMVLAAKAVKDGEADAVLSAGNTG
                     ALLAAGFFIVGRIKNIDRPGLMSTLPTVDGKGFDMLDLGANAENTAQHLHQYAVLGSF
                     YAKNVRGIAQPRVGLLNNGTESSKGDPLRKETYELLAADESLNFIGNVEARDLMNGVA
                     DVVVADGFTGNAVLKSIEGTAMGIMGLLKTAITGGGLRAKLGALLLKDSLRGLKKQLN
                     YSDVGGAVLFGVKAPVVKTHGSSDAKAVYSTIRQIRTMLETDVVAQTAREFSGE"
     gene            4146..4379
                     /locus_tag="VQ543_000732"
     CDS             4146..4379
                     /locus_tag="VQ543_000732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HET2611485.1"
                     /translation="MTEKEIFDRIVTIIQERQGEDFVVTESLSLKDDLDADSVDLMEF
                     ILTLEDEFSIEISDEEIDQLQSVGDVVKIIQGK"
     gene            4425..4716
                     /locus_tag="VQ543_000733"
                     /pseudo
     CDS             4425..4716
                     /locus_tag="VQ543_000733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
     gene            4919..5149
                     /gene="blpU"
                     /locus_tag="VQ543_000734"
     CDS             4919..5149
                     /gene="blpU"
                     /locus_tag="VQ543_000734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpU"
                     /protein_id="HET2611486.1"
                     /translation="MNTKKMSQFEIMDTEMLACVEGGGCNWGDFAKAGVGGGAVRGLQ
                     LGIKTRTWQGAATGAAGGAILGGVAYAATCWW"
     gene            5864..8017
                     /locus_tag="VQ543_000735"
     CDS             5864..8017
                     /locus_tag="VQ543_000735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000668284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide cleavage/export ABC transporter"
                     /protein_id="HET2611487.1"
                     /translation="MKFGKRHYRPQVDQMDCGVASLAMVFGYYGSYYFLAHLRELAKT
                     TMDGTTALGLVKVAEEIGFETRAIKADMTLFDLPDLTFPFVAHVLKEGKLLHYYVVTG
                     QDKDSIHIADPDPGVKLTKLPRERFEEEWTGVTLFMAPSPDYKPYKEQKNGLLSFIPI
                     LVKQRGLIANIVLATLLVTGINIVGSYYLQSIIDTYVPDQMRSTLGIISIGLVIVYIL
                     QQILSYAQEYLLLVLGQRLSIDVILSYIKHVFHLPMSFFATRRTGEIVSRFTDANSII
                     DALASTILSIFLDVSTVVIISLVLFSQNTNLFFMTLLALPIYTVIIFAFMKPFEKMNR
                     DTMEANAVLSSSIIEDINGIETIKSLTSESQRYQKIDKEFVDYLKKSFTYSRAESQQK
                     ALKKVAHLLLNVGILWMGAVLVMDGKMSLGQLITYNTLLVYFTNPLENIINLQTKLQT
                     AQVANNRLNEVYLVASEFEEKKTVEDLSLMKGDMTFKQVHYKYGYGRDVLSDINLTVP
                     QGSKVAFVGISGSGKTTLAKMMVNFYDPSQGEISLGGVNLNQIDKKALRQYINYLPQQ
                     PYVFNGTILENLLLGAKEGTTQEDILRAVELAEIREDIERMPLNYQTELTSDGAGISG
                     GQRQRIALARALLTDAPVLILDEATSSLDILTEKRIVDNLMALDKTLIFIAHRLTIAE
                     RTEKVVVLDQGKIVEEGKHADLLAQGGFYAHLVNS"
     gene            8030..9379
                     /locus_tag="VQ543_000736"
     CDS             8030..9379
                     /locus_tag="VQ543_000736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000801614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyD family secretion protein"
                     /protein_id="HET2611488.1"
                     /translation="MKPEFLESAEFYNRRYHNFSSSVIVPMALLLVFLLGFATVAEKE
                     MSLSTRATVEPSRILANIQSTSNNRILVNHLEENKLVKKGDLLVQYQEGAEGVQAESY
                     ASQLDMLKDQKKQLEYLQKSLQEGENHFPEEDKFGYQATFRDYISQAGSLRASTSQQN
                     ETIASQNAAASQTQAEIGNLISQTEAKIRDYQTAKSAMETGASLASQNLAYSLYQSYK
                     SQGEENPQTKVQAVAQVEAQISQLESSLATYRVQYAGSGTQQAYASGLSSQLESLKSQ
                     HLAKVGQELTLLAQKILEAESGKKVQGNLLDKGKITASEDGVLHLNPETSDSSMVAEG
                     ALLAQLYPSLEREGKAKLTAYLSSKDVARIKVGDSVRYTTTHDAGNQLFLDSTITSID
                     ATATKTEKGNFFKIEAETNLTSEQAEKLRYGVEGRLQMITGKKSYLRYYLDQFLNKE"
     gene            9550..10257
                     /locus_tag="VQ543_000737"
     CDS             9550..10257
                     /locus_tag="VQ543_000737"
                     /EC_number="6.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000043309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HET2611489.1"
                     /translation="MSKQLIYSGKAKDIYTTEDENLIISTYKDQATAFNGVKKEQIAG
                     KGVLNNQISSFIFEKLNAAGVATHFVEKLSDTEQLNKKVKIIPLEVVLRNYTAGSFSK
                     RFGVDEGIALETPIVEFYYKNDDLDDPFINDEHVKFLQIAGDQQIAYLKEETRRINEL
                     LKVWFAEIGLKLIDFKLEFGFDKDGKIILADEFSPDNCRLWDADGNHMDKDVFRRGLG
                     ELTDVYEIVWEKLQELK"
     gene            10459..14184
                     /locus_tag="VQ543_000738"
     CDS             10459..14184
                     /locus_tag="VQ543_000738"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000361233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase"
                     /protein_id="HET2611490.1"
                     /translation="MDKRIFVEKKADFQVKSESLVRELQHNLGLSSLKSIRIVQVYDV
                     FDLAEDLFAPAEKHIFSEQGTDHVLDEVSVQADLANYAFFAIESLPGQFDQRAASSQE
                     ALLLLGSSSDVTVNTAQLYLVNKDIDATELEAVKNYLLNPVDSRFKDITTGIAKQEFS
                     ESDKTIPKLTFFESYTAEDFARYKAEQGMAMEVDDLLFIQDYFKSIGRVPTETELKVL
                     DTYWSDHCRHTTFETELKHIDFSASKFQKQLQSTYDKYIAMREELGRSEKPQTLMDMA
                     TIFGRYERANGRLDDMEVSDEINACSVEIEVDVDGVKEPWLLMFKNETHNHPTEIEPF
                     GGAATCIGGAIRDPLSGRSYVYQAMRISGAGDITAPISETRAGKLPQQVISKTAAHGY
                     SSYGNQIGLATTYVREYFHPGFVAKRMELGAVVGAAPKGNVVREKPEAGDVIILLGGK
                     TGRDGVGGATGSSKVQTVESVETAGAEVQKGNAIEERKIQRLFRNGNVTRLIKKSNDF
                     GAGGVCVAIGELADGLEIDLNKVPLKYQGLNGTEIAISESQERMAVVVRPEDVDTFVA
                     ECNKENIDAVVVATVTEKPNLVMHWNGETIVDLERRFLDTNGVRVVVDAKVVDKDVKL
                     PEERQTSAETLESDTLTVLSDLNHASQKGLQTIFDCSVGRSTVNHPLGGRYQLTPTEA
                     SVQKLPVQHGVTHTASVIAQGFNPYVAEWSPYHGAAYAVIEATARLVAAGANWSKARF
                     SYQEYFERMDKQAERFGQPVAALLGSIEAQIQLGLPSIGGKDSMSGTFEELTVPPTLV
                     AFGVTTADSRKVLSPEFKAVGENIYYIPGQALSAEIDFDLIKKNFAQFEASQADHKVT
                     SASAVKYGGVVESLALATFGNYIGAEVTLPELKTALTAQLGGFVFTSPEEIAGVEKIG
                     QTKADFTLTVNGVKLDGHKLDSAFQGTLEEVYPTEFTQAKELEEVPAVASDVVIKAKE
                     KVEKPVVYIPVFPGTNSEYDSAKAFEKEGAEVNLVPFVTLNEEAIVKSVETMVDNIDK
                     TNILFFAGGFSAADEPDGSAKFIVNILLNEKVRVAIDSFIARGGLIIGICNGFQALVK
                     SGLLPYGNFEDANSTSPTLFYNDANQHVTKMVETRIANTNSPWLAGVQVGDIHAIPVS
                     HGEGKFVVTAEEFAELRDNGQIFSQYVDFNGKPSMDSKYNPNGSVHAIEGITSKNGQI
                     IGKMGHSERYEDGLFQNIPGNKDQHLFASAVKHFTGK"
     gene            14277..15719
                     /locus_tag="VQ543_000739"
     CDS             14277..15719
                     /locus_tag="VQ543_000739"
                     /EC_number="2.4.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000220605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidophosphoribosyltransferase"
                     /protein_id="HET2611491.1"
                     /translation="MTYEVKSLNEECGVFGIWGHPDAAKLTYFGLHSLQHRGQEGAGI
                     LSNDQGQLKRHRDMGLLSEVFRNPANLDKLTGAGAIGHVRYATAGEASVDNIQPFLFR
                     FHDMQFGLAHNGNLTNAASLKKELEQRGAIFSATSDSEILAHLIRRSHNPSLMGKIKE
                     ALSLVKGGFAYILLFEDKLIAALDPNGFRPLSIGKMANGAVVVSSETCAFEVIGAEWI
                     RDLKPGEIVIIDDEGIQYDSYTDDTQLAICSMEYIYFARPDSNIHGVNVHTARKRMGA
                     QLAREFKHEADIVVGVPNSSLSAAMGFAEESGLPNEMGLIKNQYTQRTFIQPTQELRE
                     QGVRMKLSAVSGVVKGKRVVMVDDSIVRGTTSRRIVQLLKEAGATEVHVAIGSPALAY
                     PCFYGIDIQTRQELIAANHTVEETRQIIGADSLTYLSIDGLIESIGIETDAPNGGLCV
                     AYFDGDYPTPLYDYEEDYRRSLEEKTSFYK"
     gene            15756..16778
                     /locus_tag="VQ543_000740"
     CDS             15756..16778
                     /locus_tag="VQ543_000740"
                     /EC_number="6.3.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine cyclo-ligase"
                     /protein_id="HET2611492.1"
                     /translation="MTNKNAYAQSGVDVEAGYEVVERIKKHVARTERAGVMGALGGFG
                     GMFDLSKTGVKEPVLISGTDGVGTKLMLAIKYDKHDTIGQDCVAMCVNDIIAAGAEPL
                     YFLDYVATGKNEPAKLEQVVAGVAEGCVQAGAALIGGETAEMPGMYGEDDYDLAGFAV
                     GVAEKSQIIDGSKVVEGDVLLGLASSGIHSNGYSLVRRVFADYTGEEVLPELEGKKLK
                     EVLLEPTRIYVKAVLPLIKEELVNGIAHITGGGFIENVPRMFADDLAAEIDESKVPVL
                     PIFKALEKYGQIKHEEMFEIFNMGVGLMLAVSPENVERVKELLDEAVYEIGRIVKKEN
                     ESVIIK"
     gene            16775..17320
                     /gene="purN"
                     /locus_tag="VQ543_000741"
     CDS             16775..17320
                     /gene="purN"
                     /locus_tag="VQ543_000741"
                     /EC_number="2.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylglycinamide formyltransferase"
                     /protein_id="HET2611493.1"
                     /translation="MKKIAVFASGNGSNFQVIAEEFPVEFVFSDHRDAYVLERAKQLG
                     VLSYAFELKEFESKADYEAALVELLEEHQIALVCLAGYMKIVGPTLLSAYEGRIVNIH
                     PAYLPEFPGAHGIEDAWNAGVGQSGVTIHWVDSGVDTGQVIKQVRVPRLADDTIDRFE
                     ARIHEAEYRLYPEVVKALFTD"
     gene            17404..17913
                     /locus_tag="VQ543_000742"
     CDS             17404..17913
                     /locus_tag="VQ543_000742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000894002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HET2611494.1"
                     /translation="MLESKKTTRYVFYVYLMLLTWGILFKFETNPEFIAFFLAPRYIN
                     WIPFSEPLIVDGKIVFAEMLFNLIFFIPLGVCFPLIKTNLSSLRIVGTGFLISLLFEC
                     LQYILAIGITDITDLTLNTLGVCVGLLIYQIFIRVFKSQTRKWINILGMLSLGFAYLV
                     LLLLHLIGV"
     gene            17938..19485
                     /gene="purH"
                     /locus_tag="VQ543_000743"
     CDS             17938..19485
                     /gene="purH"
                     /locus_tag="VQ543_000743"
                     /EC_number="2.1.2.3"
                     /EC_number="3.5.4.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006146083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     phosphoribosylaminoimidazolecarboxamide
                     formyltransferase/IMP cyclohydrolase"
                     /protein_id="HET2611495.1"
                     /translation="MTKRVLISVSDKADIVEFAQELKKLGWEIISTGGTKVALDNAGV
                     DTIAIDDVTGFPEMMDGRVKTLHPNIHGGLLARRDLDSHLEAAKDNKIELIDLVVVNL
                     YPFKETILKPDVTYDDAVENIDIGGPSMLRSAAKNHASVTVVVDPADYAVVLDELAAN
                     GETSYETRQRLAAKVFRHTAAYDALIAEYFTAQVGENKPEKLTLTYDLKQPMRYGENP
                     QQDADFYQKALPTDYSIASAKQLNGKELSFNNIRDADAAIRIIRDFKDSPTVVALKHM
                     NPCGIGQADDIETAWDYAYESDPVSIFGGIVVLNREVDAATAEKMHGVFLEIIIAPSY
                     TDEALAILINKKKNLRILALPFNAQEASEVEAEYTGVVGGLLVQNQDVVKESPADWQV
                     VTKRQPTETEATALEFAWKAIKYVKSNGIIVTNDHMTLGVGPGQTNRVASVRLAIDQA
                     KDRLDGAVLASDAFFPFADNVEEIAKAGIKAIIQPGGSVRDQESIEAADKYGLTMVFT
                     GVRHFRH"
     gene            19607..20869
                     /gene="purD"
                     /locus_tag="VQ543_000744"
     CDS             19607..20869
                     /gene="purD"
                     /locus_tag="VQ543_000744"
                     /EC_number="6.3.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000772208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylamine--glycine ligase"
                     /protein_id="HET2611496.1"
                     /translation="MKLLVVGSGGREHAIAKKLLESKDVEKVFVAPGNDGMTLDGLEL
                     VNISISEHSKLIDFAKTNDVAWTFIGPDDALAAGIVDDFNQAGLKAFGPTRAAAELEW
                     SKDFAKEIMVKYGVSTAAYGTFSDFEEAKAYIEKHGAPIVVKADGLALGKGVVVSETV
                     EQAVEAAHEMLLDNKFGDSGARVVIEEFFEGEEFSLFAFVNGDKFYIMPTAQDHKRAY
                     DGDKGPNTGGMGAYAPVPHLPQSVVDTAVDTIVKPVLEGMIKEGRPYLGVLYAGLILT
                     ADGPKVIEFNARFGDPETQIILPRLTSDFAQNITDILDSKEPNITWTDKGVTLGVVVA
                     SKGYPLNYSKGVELPVKTDGDIITYYAGAKFAENSRALLSNGGRVYMLVTTADTVKEA
                     QASIYQELSQQKIEGLFYRTDIGSKAIK"
     gene            21272..21760
                     /gene="purE"
                     /locus_tag="VQ543_000745"
     CDS             21272..21760
                     /gene="purE"
                     /locus_tag="VQ543_000745"
                     /EC_number="4.1.1.21"
                     /EC_number="5.4.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000805607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide mutase"
                     /protein_id="HET2611497.1"
                     /translation="MKPVISIIMGSKSDWATMQKTAEVLDRFGVAYEKKVVSAHRTPD
                     LMFKHAEEARSRGIKIIIAGAGGAAHLPGMVAAKTTLPVIGVPVKSRALSGVDSLYSI
                     VQMPGGVPVATMAIGEAGATNAALFALRLLSVEDKSIADALANFAEEQGKIAEESSNE
                     LI"
     gene            21747..22838
                     /gene="purK"
                     /locus_tag="VQ543_000746"
     CDS             21747..22838
                     /gene="purK"
                     /locus_tag="VQ543_000746"
                     /EC_number="6.3.4.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000099033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide
                     synthase"
                     /protein_id="HET2611498.1"
                     /translation="MSSSKTIGIIGGGQLGQMMAISAIYMGHKVIALDPAADCPASRV
                     AEIIVAPYNDVDALRQLADRCDVLTYEFENVDADGLDAVIKDGQLPQGTDLLRISQNR
                     IFEKDFLSNKAQVTVAPYKVVTSSLDLADIDLSKNYVLKTATGGYDGHGQKVIRSEAD
                     LEAAYALADSADCVLEEFVNFDLEISVIVSGNGKEVTFFPVQENIHRNNILSKTIVPA
                     RISESLADKAKAMAVRIAEQLNLSGTLCVEMFATDDDVIVNEIAPRPHNSGHYSIEAC
                     DFSQFDTHILGVLGAPLPVIKLHAPAVMLNVLGQHVEAAEQYVTENSSAHLHMYGKIE
                     AKHNRKMGHVTLFSDVPDSVDELGEGIDF"
     gene            22848..23075
                     /locus_tag="VQ543_000747"
     CDS             22848..23075
                     /locus_tag="VQ543_000747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazole carboxylase"
                     /protein_id="HET2611499.1"
                     /translation="MIQIIVNTFIEKDKTGAVVEVLYASADQDKVQAKYEELAAQYPE
                     NYLAIYDVPLDTDLNTLDHYPSVFIEKEEFE"
     gene            23138..24436
                     /gene="purB"
                     /locus_tag="VQ543_000748"
     CDS             23138..24436
                     /gene="purB"
                     /locus_tag="VQ543_000748"
                     /EC_number="4.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000572899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate lyase"
                     /protein_id="HET2611500.1"
                     /translation="MINRYSRPEMANIWSEENKYRAWLEVEILSDEAWAELGEIPKED
                     VALIRKKADFDIDRILEIEQETRHDVVAFTRAVSETLGEERKWVHYGLTSTDVVDTAY
                     GYLYKQANDIIRRDLENFTNIIADKAKEHKFTIMMGRTHGVHAEPTTFGLKLATWYSE
                     MKRNIERFEHAAAGVEAGKISGAVGNFANIPPFVEEYVCDKLGIRAQEISTQVLPRDL
                     HAEYFAVLASIATSIERMATEIRGLQKSEQREVEEFFAKGQKGSSAMPHKRNPIGSEN
                     MTGLARVIRGHMITAYENVALWHERDISHSSAERIITPDTTILIDYMLNRFGNIVKNL
                     TVFPENMIRNMNSTFGLIFSQRAMLTLIEKGMTREQAYDLVQPKTAYSWDNQVDFKPL
                     LEADSEVTSRLTQEEIDEIFNPVYYTKRVDDIFERLGLGD"
     gene            complement(24491..28429)
                     /gene="strH"
                     /locus_tag="VQ543_000749"
     CDS             complement(24491..28429)
                     /gene="strH"
                     /locus_tag="VQ543_000749"
                     /EC_number="3.2.1.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000679939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-N-acetylhexosaminidase"
                     /protein_id="HET2611501.1"
                     /translation="MKHEKQQRFSIRKYAVGAASVLIGFAFQAQTVAADGVTPTTTEN
                     QPTIHTVSDSPQSSENRTEETPKAELQPEAPKTVETETPATDKVASLPKTEEKPQEEV
                     SSTPSDKAEVVTPTSAEKETANKKAEEASPKKEEAKEVDSKESNTDKTDKDKPAKKDE
                     AKAEDDKPETEAGKERAATVNEKLAKKKIVSIDAGRKYFSPEQLKEIIDKAKHYGYTD
                     LHLLVGNDGLRFMLDDMSITANGKTYASDDVKRAIEKGTNDYYNDPNGNHLTESQMTD
                     LINYAKDKGIGLIPTVNSPGHMDAILNAMKELGIQNPNFSYFGKESARTVNLDNEQAV
                     AFTKALIDKYAAYFAKKTEIFNIGLDEYANDATDAKGWSVLQADKYYPNEGYPVKGYE
                     KFIAYANDLARIVKSHGLKPMAFNDGIYYNSDTSFGSFDKDIIVSMWTGGWGGYDVAS
                     SKLLAEKGHQILNTNDAWYYVLGRNADGQGWYNLDQGLNGIKNTPITSVPKTEGADIP
                     IIGSMVAAWADTPSARYSPSRLFKLMRHFANANAEYFAADYESAEQTLNEVPKDLNRY
                     TAESVAAVKEAEKAIRSLDSNLSRAQQDTIDQAIAKLQETVNNLTLTPEAQKEEEAKR
                     EVEKLAKNKVISIDAGRKYFTLNQLKRIVDKASELGYSDVHLLLGNDGLRFLLDDMTI
                     TANGKTYASDDVKKAIIEGTKAYYDDPNGTALTQAEVTELIEYAKSKDIGLIPAINSP
                     GHMDAMLVAMEKLGIKNPQAHFDKVSKTTMDLKNEEAMNFVKALIGKYMDFFAGKTKI
                     FNFGTDEYANDATSAQGWYYLKWYQLYGKFAEYANTLAAMAKERGLQPMAFNDGFYYE
                     DKDDVQFDKDVLISYWSKGWWGYNLASPQYLASKGYKFLNTNGDWYYILGQKPEDGGG
                     FLKKAIENTGKTPFNQLASTKYPEVDLPTVGSMLSIWADRPSAEYKEEEIFELMTAFA
                     DHNKDYFRANYNALREELAKIPTNLEGYSKESLEALDAAKTALNYNLNRNKQAELDTL
                     VANLKAALQGLKPAATHSGSLDENEVAANVETRPELITRTEEIPFEVIKKENPNLPAG
                     QENIITAGVKGERTHYISVLTENGKTTETVLDSQVTKEVINQVVEVGAPVTHKGDESG
                     LAPTTEVKPRLDIQKEEIPFTTVTRENPLLLKGKTQVITKGVNGHRSNFYSVSTSADG
                     KEVKTLVNSVVAQEAVTQIVEVGTMVTHVGDENGQAAIAEEKPKLEIPSQPAPSTAPA
                     EESKALPQDPAPVVIEKKLPETGTHDSAGLVVAGLMATLAAYGLTKRKED"
     gene            complement(28744..29460)
                     /locus_tag="VQ543_000750"
     CDS             complement(28744..29460)
                     /locus_tag="VQ543_000750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001007200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HET2611502.1"
                     /translation="MAIPKYQYIKDELKNKIISGQFSSGDKFYTEAELISMYDVSSIT
                     VVRALNDLAKDGYIVRQQGKGTFVSRARKHKLVEFSDIELFNAKDDKVTVLSIERGNK
                     LVYLEKLGLRGDQFYYKIERIRESNGVVYIYHTSYIPEQYINANYPNLEYYSSIYNRF
                     KLDYHIHMNDEHFEEINEIVFPTPEHAASVLGVDEQFPTVLQTKITKLESTGQVLEYS
                     ETYKRSDYYKIKFISCDRDH"
     gene            29808..31595
                     /locus_tag="VQ543_000751"
     CDS             29808..31595
                     /locus_tag="VQ543_000751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-galactosidase"
                     /protein_id="HET2611503.1"
                     /translation="MTRFEIRDDFYLDGKSFKILSGAIHYFRVPPEDWYHSLYNLKAL
                     GFNTVETYVAWNLHEPREGEFHFEGDLDLEKFLQIAQDLGLYAIVRPSPFICAEWEFG
                     GLPAWLLTKNMRIRSSDPVYIEAVGRYYDQLLPRLVPRLLDNGGNILMMQVENEYGSY
                     GEDKAYLRAIRQLMEECGVTCPLFTSDGPWRATLKAGTLIEEDLFVTGNFGSKAPYNF
                     SQMQEFFDEHGKKWPLMCMEFWDGWFNRWKEPIITRDPKELADAVREVLEQGSINLYM
                     FHGGTNFGFMNGCSARGTLDLPQVTSYDYDALLDEEGNPTAKYLAVKKMMATHFSEYP
                     QLEPLYKESMELDAIPLVEKVSLFETLDSLSSPVESLYPQKMEELGQSYGYLLYRTET
                     NWDAEEERLRIIDGRDRAQLYVDGQWVKTQYQTEIGEDIFYQGKKKGLSRLDILIENM
                     GRVNYGHKFLADTQRKGIRTGVCKDLHFLLNWKHYPLPLDNPEKIDFSKGWTQGQPAF
                     YAYDFTVEEPKDTYLDLSEFGKGVAFVNGQNLGRFWNVGPTLSLYIPHSYLKEGANRI
                     IIFETEGQYKEEIHLTRKPTLKHIKGENL"
     gene            31592..32068
                     /locus_tag="VQ543_000752"
     CDS             31592..32068
                     /locus_tag="VQ543_000752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system
                     mannose/fructose/N-acetylgalactosamine-transporter subunit
                     IIB"
                     /protein_id="HET2611504.1"
                     /translation="MTIVGCRIDGRLIHGQVANLWAGKLNVSRIMVVDDEVVNNDIEK
                     SGLKLATPPGVKLSILPVEKAAANILAGKYDSQRLFIVARKPDRFLGLVEAGVPLETL
                     NVGNMSQTPETRSITRSINVVDKDVEDFHKLAEKGVKLTAQMVPNDPISDFLSLLK"
     gene            32096..33001
                     /locus_tag="VQ543_000753"
     CDS             32096..33001
                     /locus_tag="VQ543_000753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006149155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HET2611505.1"
                     /translation="MIQWWQILLLTLYSAYQICDELTIVSSAGSPVFAGFITGLIMGD
                     VTTGLLIGGNLQLFVLGVGTFGGASRIDATSGAVLATAFSVSQGIDAPLAITTIAVPV
                     AALLTYFDVLGRMTTTFFAHRVDAAIERFDYKGIERNYLLGAIPWALSRALPVFFALA
                     FGGAFVQSVVDFVEAYKWVADGLTLAGRMLPGLGFAILLRYLPVKRNLHYLAMGFGLT
                     AMLTVLYSYVTGLGGAVAGIVGTLPAEVAEKIGFVNNFKGLSMIGISIVGIFLAVLHF
                     KNSQKVAVAAPSTPSESGEIEDDEF"
     gene            32988..33803
                     /locus_tag="VQ543_000754"
     CDS             32988..33803
                     /locus_tag="VQ543_000754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000185291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HET2611506.1"
                     /translation="MTNSNYKLTKEDFNQINKRSLFTFQLGWNYERMQASGYLYMILP
                     QLRKMYGDGTPELKEMMKVHTQFFNTSPFFHTIIAGFDLAMEEKDGVGSKDAVNGIKT
                     GLMGPFAPLGDTIFGSLVPAIMGSVAATMAIAGQPWGIFLWIAVAVAYDIFRWKQLEF
                     AYKEGVNLINNMQSTLTALIDAASVLGVFMMGALVATVINFEISYKLPIGEKMIDFQD
                     ILNQIFPRLLPAIFTAFIFWLLGKKGMNSTKAIGIIIVLALALSALGHFALGM"
     gene            33810..34214
                     /locus_tag="VQ543_000755"
     CDS             33810..34214
                     /locus_tag="VQ543_000755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007284837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HET2611507.1"
                     /translation="MTKSLILVSHGRFCEELRGSTEMIMGPQDNIYTVALLPEDGPEE
                     FTAKFEAVIEGLDDFLVFADLLGGTPCNVVSRLIMEGRDIDLYAGMNLPMVIEFINAS
                     LTGADADYKSRAAESIVKVNDLLAGFDDDEDE"
     gene            34513..35679
                     /locus_tag="VQ543_000756"
     CDS             34513..35679
                     /locus_tag="VQ543_000756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HET2611508.1"
                     /translation="MLHYTKEDLLELGAEITTREIYQQPDVWREAFEFYQAKREEIAA
                     FLQEIADKHDYIKVILTGAGTSAYVGDTLLPYFKEVYDERKWNFNAIATTDIVAKPAT
                     YLKKDVATVLVSFARSGNSPESVATVDLAKSLVDELYQVTITCAADGKLALQAHGDDR
                     NLLLLQPAVSNDAGFAMTSSFTSMMLTTLLVFDPTEFAVKSERFEVVSSLARKVLDKA
                     EDVKELVDLDFNRVIYLGAGPFFGLAHEAQLKILELTAGQVATMYESPVGFRHGPKSL
                     INDNTVVLVFGTTTDYTRKYDLDLVREVAGDQIARRVVLLSDQAFGLENVKEVVLGCG
                     GVLNDIYRVFPYIVYAQLFALLTSLKVENKPDTPSPTGTVNRVVQGVIIHEYQK"
     gene            35795..36832
                     /locus_tag="VQ543_000757"
     CDS             35795..36832
                     /locus_tag="VQ543_000757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose mutarotase"
                     /protein_id="HET2611509.1"
                     /translation="MKAYTERVFGNVEGEDVLAYRFETDGGYQLEVMTYGATILRYVA
                     PDKAGNFANVILGFDDFDSYVGNSPKHGASVGPVAGRIAGATFELNGKTYDLEVNNAS
                     NCNHSGSTGWDSSLFEVEEVSDHGLTLYTERTDGTGGFPGNLKIWISYHLEETGAYEI
                     SYKVTTDQDTLVNPTNHSYFNLSGDFTQTIDRHVFQLNTEGIYSIAPDGVPAKTPEAN
                     RDVVKHIYNGALLKDIFAEEDEQIQLASGLDHPFALPAGHDNAGFLYDQNSGRFLLFK
                     TEAPCFVVYTANFVDESVIIGGQPMLQHNGIALEAQALPDAIHSDLKGQVILKAGQTF
                     TSKTRYELVVK"
     gene            37040..37894
                     /locus_tag="VQ543_000758"
     CDS             37040..37894
                     /locus_tag="VQ543_000758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000220702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HET2611510.1"
                     /translation="MTYEYKSHIYLAETALNVKDLASQTAFYQQVIGLEILSQTETES
                     ILGLGGKVLVQLIQAQESGEVREYYGLYHLAILLPTRKALADVLKHLTDLQIPLVGGA
                     DHGYSEAIYLEDLEGNGIELYRDKPVSTWDIREDGRIIGVTEALAAQDIYELGERVEP
                     FILAEGTRMGHIHLSVKDSRKSSQFYQKVLGLEDKFSVPSASWIAAGDYHHHLAVNEW
                     GGKGLASRKQGLPGLAYYVIEVAHKKELLTIAQRAQEVDAPIKWMTSSQLEITDSDGI
                     VTRIRLAR"
     gene            38044..38301
                     /locus_tag="VQ543_000759"
     CDS             38044..38301
                     /locus_tag="VQ543_000759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001845567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sensitive transcriptional regulator"
                     /protein_id="HET2611511.1"
                     /translation="MTNSKYITCLKRSEGQLCGIQKMIEGDRDCADIVTQLTAVRSSV
                     ERVIEMIITENLTECINQPLDDSEAQKERLEKAIRYLIKRK"
BASE COUNT        10794 a         7451 c         9141 g        11179 t
ORIGIN      
        1 aacatatata cggcaaggcg acgttgacgt ggtttgaaga gattttcgaa gagtgttaga
       61 aaatgccgat aagggtctgc ataccaagag tggtgaggat gatggcaatc cagcagatgg
      121 ctccaagaag aatggatttt ccactggatt tgaccatagc gaccagattg gttttgagac
      181 cgatagcact catggccatg acaataagga atttagagag ttctttgaga ggggtaaaga
      241 aactactgga cacacctaga gaggtgagta gtgtagtgag gagagaggca aggataaagt
      301 aaaggataaa aagtgggaag acttttttca gttgtaggct ttgcttgttt tcttgttggc
      361 gactttgcca gtaggagaga aagagcgtga tagggataat agccaaagta cgtgtgagtt
      421 taacaatggt tgcagactcg agggtattgc tttggtaaag actgtcccaa gcgctggcgg
      481 cagccgttac agaggaagtg tcgttgaccg cagtccctgc aaagagggcg aagccttcat
      541 tggatagatg aagccaggtg ccgagggttg gaaagatgag cgcagccaag acattgaaga
      601 aaaagataac ggaaatggct tgggctactt ccttttcctt agcatcaata acgggcgctg
      661 tcgctgcaat ggcagaaccc ccacagatag aagaacctac tccaaccaag gtagccagtt
      721 ttgtatccag tgcaaagaaa cgctggaaga ggtaggcaat aatcagagct attgagatag
      781 tggacaggat gacagggagt gaagattggc caactgcgaa gacctgcgag atattgagac
      841 caaaaccaag caagacaacg gcatattgga gcaacttctt ggaactaaag gtcaaaccag
      901 catccagttg tttataggac gagagaaagg gatgtaggag catgcctatg aaaatggcaa
      961 aaacgggcgc gccaatcaca gggaagaatc ctcctaagta ccaagatacg atagaaatga
     1021 gaaggcaggc caagatacct gctccatttt ttgatagaaa tgacataaaa acctccaaat
     1081 aaaatctatt accattatag acctataaac aggaaaagta aaatagaaag tggaaagcta
     1141 ttctctaatg tatttttgcg gtcggggggc ttttgtagta taatagagat acgttttgaa
     1201 agtaggaggt atctatggac ttaactaagc gctttaataa acagttagat aaaattcaag
     1261 tttcgttgat tcgtcagttt gaccaggtta tttcggagat tcctggggtc ttgcgtttga
     1321 ccttggggga acctgatttt acaacgccag accatgtcaa ggaggcggcc aagcgagcga
     1381 ttgatcagaa ccaatcctac tatacaggga tgagtggtct gctgactcta cgtcaggcag
     1441 ccagtgactt tgttaaggaa aagtaccaac tggactatgc tcctgaaaat gaaattttgg
     1501 ttacaattgg ggcgacagag gctttatctg cgactttgac ggctattttg gaagagggag
     1561 acaaggtact tttgccagct cctgcttatc caggctatga accgattgtt aacttagttg
     1621 gggcagaaat tgttgagatt gatacgactg aaaatggttt tgtcttgact cctgagatgt
     1681 tggagaaggc cattttggag cagggtgata agctcaaggc ggttattctc aactatccag
     1741 ccaatccgac aggaattacc tacagtcgag agcagttaga ggccttggca gctgttttac
     1801 gcaagtacga aatttttgtt gtctgtgatg aggtttactc agaattgacc tacacaggcg
     1861 aagcccatgt gtctctagga acgatgttga gagaccaggc tattattatc aatggtttgt
     1921 ctaaatcgca tgccatgaca ggttggcgtt tggggctgat tttcgctcct gcggccttca
     1981 cagcccagtt aatcaagagt caccaatact tggtcactgc cgcaaatacc atggcgcaac
     2041 atgctgcggt agaagccttg acggctggta aaaatgatgc ggagcccatg aagaaggaat
     2101 atatccaacg tcgggactat atcatcgaaa aaatgactgc tcttggtttt gagattatca
     2161 aaccagacgg tgccttctat atttttgcta aaattccagc gggctacaat caagactcct
     2221 ttgcttttct gaaggatttt gctcagaaga aggccgttgc ctttatccct ggtgcagcct
     2281 ttggacgtta cggggaaggc tacgtccgcc tatcttatgc agccagcatg gagactatca
     2341 aagaagccat gaaacgactt gaggagtaca tgagagaagc atgattcagt ctatcacgag
     2401 tcaaggcttg gtgctttaca atcgcaattt tcgtgaggat gacaagctcg tcaaaatttt
     2461 tacagagcag gttggcaaac gcatgttttt tgtcaaacac gctggtcagt ctaagctggc
     2521 gcctgttatt cagcccttgg tgctggcacg atttctcttg cgaatcaatg atgacggact
     2581 cagttacatc gaagactatc atgaggtcat gacttttccc aagattaata gtgacctctt
     2641 tgtcatggcc tatgcgacct atgtggcagc tcttgcagat gctagtttgc aggacaatca
     2701 gcaggatgct cccttgtttg cttttttgca aaagactttg gagttgatgg aagcaggctt
     2761 ggattatcag gttttgacca atatttttga aattcaaatt ttgactcgat ttggaatcag
     2821 cctcaatttt aatgagtgtg tcttctgcca tcgggttggt caggcttttg acttttcttt
     2881 caaatatgga gcctgcctct gtccagagca ttatcatgag gataagagac gttgtcatct
     2941 caatcccaat atcccctatc tgctcaatca atttcaagct attgattttg agactttgga
     3001 gaccatttcg ctcaagcctg gaatcaagca agagctacgc caatttatgg atcaattata
     3061 tgaagagtac gttgggattc acctaaaatc aaagaaattt attgattccc tagcagactg
     3121 gggacaatta ctaaaagagg aaaagaaatg aaaaaaatcg cagtagatgc catggggggc
     3181 gattacgcac ctcaggccat tgttgagggt gtcaatcaag ccctatctga cttttcagat
     3241 atcgaggttc aactttacgg agatgaagct aaaatcaagc aatatctgac agcgacagag
     3301 cgcgtcagca ttatccatac ggatgagaag attgattcgg atgatgaacc tacgagagct
     3361 attaggaata agaaaaatgc cagtatggta ttggcagcca aggctgtcaa agatggtgaa
     3421 gcagacgctg tcctttcggc tgggaataca ggtgccttgt tggcagcagg attcttcatc
     3481 gtgggtcgta tcaagaatat cgaccgtcct ggactcatgt ctaccttgcc taccgttgat
     3541 ggaaaaggtt ttgacatgct agaccttggt gccaatgcag aaaatacagc ccagcacctc
     3601 catcaatatg cggttctagg ttccttctat gctaaaaatg tccgtggcat tgcgcaacca
     3661 cgcgttggtt tgctcaacaa cggaacagag agtagcaagg gcgacccgct tcgtaaggaa
     3721 acttatgaat tactggcggc tgatgaaagt ttgaacttta tcggaaacgt ggaagcgcgt
     3781 gatttgatga atggcgttgc agatgttgtt gtggcagatg gtttcacggg aaacgctgtg
     3841 ctcaaatcca tcgaagggac agctatggga atcatgggct tgctcaagac agctattaca
     3901 ggtggtggtc ttcgagcgaa actaggtgcc ctccttctca aggacagcct cagaggtttg
     3961 aaaaaacagc tcaattattc agatgttggt ggagcggtct tgtttggtgt taaggcacct
     4021 gttgtcaaga ctcatggctc aagcgatgcc aaggctgttt atagtacgat tcgtcagatc
     4081 cgtaccatgc tagaaacaga cgtggttgcc cagactgcgc gtgaattttc aggagaataa
     4141 aagagatgac agaaaaagaa atttttgacc gtattgtgac cattatccaa gagcgacagg
     4201 gagaggactt tgtcgtgaca gaatccttga gtctgaaaga cgatttggat gcggattctg
     4261 ttgacttgat ggagtttatc ttgactctgg aagatgaatt tagtatcgaa atcagcgatg
     4321 aggaaattga ccaactccaa agtgtaggag atgtggttaa aatcattcaa ggaaaatagc
     4381 aatcggagtt ccaagtcaac ggaagtagat ggtttttaga aatgagaaat atcggacaag
     4441 ctggtaaaat cttggctgac agtggttatc aagggctcat gaagatatat cctcaagcac
     4501 aaacttccac gtaaatccag caaactcaag ccgctaacag ttgaagataa agcctgtaat
     4561 catgcgctat ctaaggagag aagcaaggtt gagaatatct ttgccaaagt aaaaacgttt
     4621 aaaatgtttt caacaaccta tcgaaatcat cgtaaacgct tcggattacg aatgaatttg
     4681 attgctggta ttatcaatca tgaactagga ttctagtttt gcaggaagtc taatagtaaa
     4741 aaagtgatta gaaaacatct tttttaaaaa tagagatgat tttgaaacaa aaaagctaat
     4801 tcaagacgtt tcgatgccaa ttcaagattt ggatgaaaaa aattaataga tactgttata
     4861 ctaaacttgt caagtttgta acaagacaaa tattaaaaat aaaaaagagg tattcgttat
     4921 gaatacaaaa aagatgtcac aatttgaaat tatggatact gagatgcttg cttgcgttga
     4981 aggtggcgga tgcaattggg gagattttgc caaagcaggt gttggaggag gagcagtacg
     5041 aggtcttcag ctaggaatta aaacaagaac atggcaaggt gcagcaactg gtgctgcggg
     5101 aggagctata cttggaggtg tggcctatgc agcgacatgt tggtggtaat tatggatttt
     5161 aaaagtttta ttattggttt agtagttggt atatttggtc cttatatgga tgatttaatt
     5221 agaaaaaaat ttttaaagtc ttcggagaag aaaacagaaa aatctgttaa aaaataatca
     5281 aaactataaa tgatgaatct gaatcaaaat tattttgcgc atgtaaagag gagtcttata
     5341 gtaacgagtc aaaaaaggag taactatgaa tcgtaattta gaacggtgtt atctattctg
     5401 actaggaata gatcatacca gaggtagctt agaaatagca gggacattag aaattgaagt
     5461 aataaatagg atgtcgtaag tgttactatc aatgatttat ttgtttcaag cttgcctagg
     5521 gtgacagtaa aaaatcaatt tcctttcaat agcatatttt tagtgggcag gactcttgtt
     5581 ctgcctattt ttttatccaa aaagtgcagt tgggagggag ataggctcat ttgggaagga
     5641 agtccagttt ttgtttagtg attggggtaa gatagttgtt atcagatgag tttatactct
     5701 tcgaaaatca aattcaaacc acgtcaacgt cgccttgccg tatatatgtg actgacttcg
     5761 tcagtcctat ctacaacctc aaaacagtgt tttgagcagc ctgcggctag tttcctagtt
     5821 tgctctttga ttttcattga gtattaggga aaaggagatg aatatgaaat ttgggaaacg
     5881 tcactatcgt ccgcaagtgg atcagatgga ctgcggtgta gcttcattag ccatggtttt
     5941 tggctactat ggtagttatt attttttggc tcacttgcga gaattggcta agacgaccat
     6001 ggatgggacg acggctttgg gcttggtcaa ggtggcagag gagattggtt ttgagacgcg
     6061 agccattaag gcggatatga cgctttttga cttgccggat ttgacttttc cttttgttgc
     6121 ccatgtgctt aaggaaggga aattgctcca ctactatgtg gtgactgggc aggataagga
     6181 tagcattcat attgccgatc cagatcccgg ggtgaagttg actaaactgc cacgtgagcg
     6241 ttttgaggaa gaatggacag gagtgactct ttttatggca cctagtccag actataagcc
     6301 ttataaggaa caaaaaaatg gtctgctctc ttttatccct atattagtga agcagcgtgg
     6361 cttgattgcc aatatcgttt tggcaacact cttggtaacc gggattaaca ttgtgggttc
     6421 ttattatctg cagtctatca ttgataccta tgtgccagat cagatgcgtt cgacactagg
     6481 gattatttct attgggctag tcatcgtcta catcctccag caaatcttgt cttacgctca
     6541 ggagtatctc ttgcttgttt tggggcaacg cttgtcgatt gacgtgattt tgtcctatat
     6601 caagcatgtt tttcacctcc ctatgtcctt ctttgcgaca cgcaggacag gggagatcgt
     6661 gtctcgtttt acagatgcta acagtatcat cgatgcgctg gcttcgacca tcctttcgat
     6721 tttcctagat gtgtcaacgg ttgtcattat ttcccttgtt ctattttcac aaaataccaa
     6781 tctctttttc atgactttat tggcgcttcc tatctacaca gtgattatct ttgcctttat
     6841 gaagccgttt gaaaagatga atcgggatac catggaagcc aatgcggttc tgtcttcttc
     6901 tatcattgag gacatcaacg gtattgagac tatcaagtcc ttgaccagtg aaagtcagcg
     6961 ttaccaaaaa attgacaagg aatttgtgga ttatctgaag aaatccttta cctatagtcg
     7021 agcagagagt cagcaaaagg ctctgaaaaa ggttgcccat ctcttgctta atgtcggcat
     7081 tctctggatg ggggctgttc tggtcatgga tggcaagatg agtttggggc agttgattac
     7141 ctataatacc ttgctggttt actttaccaa tcctttggaa aatatcatca atctgcaaac
     7201 caagcttcag acagcgcagg ttgccaataa ccgtctaaat gaagtgtatc tagtagcttc
     7261 tgagtttgag gagaagaaaa cagttgagga tttgagcttg atgaagggag atatgacctt
     7321 caagcaggtt cattacaagt atggctatgg tcgagacgtc ttgtcggata tcaatttaac
     7381 cgttccccaa gggtctaagg tggcttttgt ggggatttca gggtcaggta agacgacttt
     7441 ggccaagatg atggttaatt tttacgaccc aagtcaaggg gagattagtc tgggtggtgt
     7501 caatctcaat cagattgata aaaaagccct gcgccagtac atcaactatc tgcctcaaca
     7561 gccctatgtc tttaacggaa cgattttgga gaatcttctt ttgggagcca aggaggggac
     7621 gacacaggaa gatatcttac gggcggtcga attggcagag attcgagagg atatcgagcg
     7681 catgccactg aattatcaga cagaattgac ttcggatggg gcagggattt caggtggtca
     7741 acgtcagaga atcgctttgg cgcgtgctct cttgacagat gcgccggtct tgattttgga
     7801 tgaggcgact agcagtttgg atattttgac agagaagcgg attgtcgata atctcatggc
     7861 tttggacaag accttgattt tcattgctca ccgcttgact attgctgagc ggacagagaa
     7921 ggtggttgtc ttggatcagg gcaagattgt cgaagaagga aagcatgctg atttgcttgc
     7981 acagggaggc ttttacgccc atttggtcaa tagctagaaa gaggagagga tgaaaccaga
     8041 atttttagaa agtgcggagt tttataatcg tcgttaccat aatttttcca gtagtgtgat
     8101 tgtacccatg gcccttctgc tcgtgttttt acttggcttt gcaactgttg cagagaagga
     8161 gatgagtttg tccactagag ctactgtcga acccagtcgt atccttgcaa atatccagtc
     8221 aactagcaac aatcgtattc ttgtcaatca tttggaagaa aataagctgg ttaagaaggg
     8281 ggatctcttg gttcaatacc aagaaggggc agagggtgtc caagcggagt cctatgccag
     8341 tcagttggac atgctaaagg atcaaaaaaa gcaattggag tatctgcaaa agagcctgca
     8401 agaaggggag aaccactttc cagaggagga taagtttggc taccaagcca cctttcgcga
     8461 ctacatcagt caagcaggca gtcttagggc tagtacatcg caacaaaatg agaccatcgc
     8521 gtcccagaat gcagcagcta gccaaaccca agccgaaatc ggcaacctca tcagtcaaac
     8581 agaggctaaa attcgcgatt accagacagc taagtcagct atggaaacag gtgcttcctt
     8641 ggccagtcag aatctagcct actctcttta ccagtcctac aagtctcagg gcgaggaaaa
     8701 tccccaaact aaggttcagg cagttgcaca ggttgaagca cagatttctc agttagaatc
     8761 tagtcttgct acttaccgtg tccagtatgc aggttcaggt acccagcaag cctatgcgtc
     8821 agggttaagc agtcaattgg aatcccttaa atcccaacat ttggcaaagg ttggtcagga
     8881 attgaccctt ctagcccaga aaatcttgga ggcagagtca ggtaagaagg tacagggaaa
     8941 tcttttagac aaggggaaaa ttacggcgag tgaggatggg gtgcttcatc ttaatcctga
     9001 gaccagtgat tctagcatgg ttgcagaagg tgccctacta gcccaacttt atccatcttt
     9061 ggaaagagaa gggaaagcca aactcacagc ctatctaagt tcaaaagatg tagcaagaat
     9121 caaggtcggt gattctgttc gctatactac gactcatgat gccgggaatc aacttttcct
     9181 agattctact attacaagta ttgatgcgac agctactaag actgagaaag ggaatttctt
     9241 taaaatcgag gcggagacta atctaacttc ggagcaggct gaaaaactta ggtacggggt
     9301 ggaaggccgc ttgcagatga ttacgggcaa gaaaagttat ctacgttatt atttggatca
     9361 atttttgaac aaagagtaat gttcgtgttt ttagagttaa ataattttta aactgtgaga
     9421 aagattcttc ttgcagtttt ttctttacaa tttttaaaaa aacatctgct atttattcgg
     9481 ttaaattctt gtgttttttg gttttttgtg gtaaaatgtg ctcaagtaat acgaaaggcg
     9541 aactttaaaa tgtcaaaaca attgatctat tcgggaaaag ctaaagatat ctatacaact
     9601 gaggatgaaa atcttattat ttcaacttac aaggaccagg cgactgcttt caacggtgtc
     9661 aagaaggagc agattgcagg taagggagtc ttgaataatc agatctcatc ttttattttt
     9721 gagaaattaa atgcggctgg tgtggcgact cactttgtgg agaaactttc agacacggaa
     9781 caactcaata aaaaggttaa gattattcct ttggaagtcg tgctccgcaa ctatactgct
     9841 ggttcctttt caaaacgttt tggtgtggat gagggaatcg ccttggagac tccgattgtc
     9901 gaattttact acaaaaatga tgatttggat gatccattta tcaatgatga gcatgtgaaa
     9961 ttcctacaga ttgcgggtga ccagcagatt gcctacttga aggaagaaac gcgtcgtatc
    10021 aatgaactat tgaaagtctg gtttgctgag attgggctta aattgattga ctttaagcta
    10081 gagttcggtt ttgacaagga tggcaagatt atcttggcag acgaattttc accagataac
    10141 tgccgcttgt gggacgctga tggcaaccac atggataagg atgttttccg tagaggattg
    10201 ggagaactaa ccgacgttta tgagattgtt tgggaaaagt tgcaggaatt gaaataatct
    10261 gtttgcaacg gaaaaccttc gtctctcaac taaaaggact caggctgaaa aggtccccca
    10321 gaccttttca ctctgtagag aactaggtga actaacagat gtttacgaaa ttgtctggga
    10381 aaagttgcag ggtttaaaat aacaacctca aggctgtttg ggaatattgc aagagctgaa
    10441 ataaaggaat aagaattgat ggataaacgt atttttgttg aaaaaaaggc tgattttcag
    10501 gtcaagtcag agagtttggt tagagagctc cagcacaact tgggactgtc aagcttgaaa
    10561 agtattcgta ttgtgcaagt atatgatgta tttgacttgg ctgaggactt gtttgcacct
    10621 gcagagaagc acattttctc tgagcaggga accgaccatg ttttagatga agtatctgtg
    10681 caggcggatc ttgctaacta tgctttcttt gccattgaaa gtctgccagg gcagtttgac
    10741 cagcgtgcag cttcgtcaca ggaagccttg cttttgttgg gaagttcgag tgacgtgaca
    10801 gtcaacacag cccaacttta cttggtgaat aaagatattg atgcgactga gttggaagct
    10861 gtcaaaaact acctgctcaa tccagttgat tctcgtttca aggatatcac gacagggatt
    10921 gccaagcagg agttttcaga gtcagacaag accattccaa aattgacttt ctttgaaagc
    10981 tatacagcag aagactttgc tcgctacaag gccgagcaag ggatggccat ggaagtggat
    11041 gatttgctct ttatccaaga ctactttaag tcaatcgggc gcgtgccaac tgagactgaa
    11101 ctcaaggttt tggacactta ctggtctgac cactgccgtc atacgacttt tgagacagag
    11161 ttgaaacaca tcgacttttc agcttctaaa tttcaaaagc aattgcagtc aacctatgac
    11221 aagtatattg ccatgcgcga ggagttaggt cggtctgaaa aaccacaaac cttgatggat
    11281 atggcgacta ttttcggtcg ttatgagcgt gctaacggac gattggatga tatggaagtc
    11341 tctgacgaaa tcaatgcctg ctcagttgaa attgaagtgg atgttgatgg tgtcaaggaa
    11401 ccttggctcc tcatgtttaa aaatgaaacc cacaaccatc caacagaaat tgagccattt
    11461 ggtggagcgg ctacctgtat cggtggagct attcgtgatc cgttgtcagg ccgttcctat
    11521 gtttaccaag ccatgcgtat ttcaggtgct ggtgatatta cagcaccgat ttcggaaact
    11581 cgtgctggga aattgccaca acaagtcatt tctaaaacag cagctcatgg ttattcttca
    11641 tatggtaacc agattgggct tgccacaacc tacgttcgtg aatacttcca cccaggcttt
    11701 gtagctaaac gtatggaact tggtgccgtt gttggtgcgg ctcccaaggg caatgttgtc
    11761 cgtgaaaaac ctgaagcagg tgatgtgatc atccttctcg gaggcaaaac aggtcgtgat
    11821 ggtgtcggtg gtgcgacggg ctcttctaag gttcaaacag ttgagtctgt agagactgct
    11881 ggtgctgagg ttcaaaaagg aaatgccatc gaagaacgca agattcagcg cctcttccgt
    11941 aatggcaatg tcactcgtct gatcaagaag tccaatgact ttggggcagg cggcgtctgt
    12001 gtggctatcg gtgaattggc agacggtctt gaaatcgacc tcaacaaggt gcctcttaaa
    12061 taccagggct tgaatggtac agaaattgcc atctctgaat cacaagaacg gatggcggtc
    12121 gtggttcgtc ctgaagatgt ggataccttc gttgccgaat gtaacaaaga aaatattgat
    12181 gctgttgtgg tggcgacagt aactgaaaaa ccaaatcttg tcatgcactg gaatggtgag
    12241 acaatcgttg acttggagcg tcgtttcctt gacaccaatg gtgtgcgcgt ggttgtcgat
    12301 gccaaagttg tggacaagga tgtcaaactc ccagaagagc gtcaaacatc tgctgaaaca
    12361 ctggaatcag atacccttac ggttctatct gacctcaacc atgcaagtca aaaaggatta
    12421 cagactatct ttgactgctc tgttggacgc tcaacggtta atcacccact tggtggtcgt
    12481 taccaactca caccaactga ggcatctgtg cagaaattgc cagttcaaca cggtgtgact
    12541 catactgcgt cggtcattgc tcaaggtttc aacccatatg tagctgaatg gtctccatac
    12601 cacggtgctg cttatgcggt tatcgaagca actgctcgtt tggtggctgc tggtgccaac
    12661 tggtctaagg ctcgtttctc ttaccaagaa tatttcgagc ggatggacaa gcaagcagag
    12721 cgtttcggtc agccagtagc tgctcttcta ggttctattg aagcacaaat tcagcttggc
    12781 ttgccatcta tcggtggtaa ggactccatg tctggtacct ttgaagaatt gaccgttccg
    12841 ccaaccttgg ttgcctttgg ggtgacgacg gcagatagcc gtaaggtgct ctctccagaa
    12901 tttaaagctg ttggggaaaa tatctactac atcccaggtc aagccctctc tgcagagatt
    12961 gattttgact tgattaagaa aaattttgct cagtttgaag caagccaagc tgaccataaa
    13021 gtgacgtctg catcagctgt caaatacggt ggtgtagttg aaagtttggc tcttgctacc
    13081 tttggaaact atattggtgc agaggtgacc ttgcctgaac ttaaaacagc tttgacagct
    13141 caattaggcg gctttgtctt cacatctcct gaagaaattg ctggagtaga gaagattgga
    13201 caaacgaaag cagactttac actgactgtc aacggtgtga agctagatgg acacaagctt
    13261 gacagtgcat ttcaagggac attggaagaa gtttacccaa cagaatttac ccaagcgaaa
    13321 gaactagaag aagtaccagc tgtggcatca gatgttgtga ttaaagccaa agaaaaggtt
    13381 gaaaaacctg tggtttacat cccagtcttt ccaggaacca actcagaata tgattcagct
    13441 aaggccttcg aaaaagaagg tgcagaggtc aatttggtgc cattcgtgac cttgaatgaa
    13501 gaagctattg tcaagtcagt tgaaactatg gttgacaata tcgacaagac taatattctc
    13561 ttctttgccg gtggattctc ggctgcggat gaaccagatg gttcagctaa gtttatcgtc
    13621 aatatcctgc ttaatgaaaa agtgcgtgtg gctattgata gctttatcgc ccgtggtggc
    13681 ttgattatcg gtatttgtaa tggattccaa gccttagtca aatcgggtct cctaccatac
    13741 ggaaactttg aagatgctaa cagtactagt ccaaccctct tctacaatga tgccaaccaa
    13801 cacgtgacca agatggtgga aactcgcatt gccaatacca actcaccatg gttggctggt
    13861 gtgcaagtgg gcgatatcca cgctattcct gtttcgcacg gtgaagggaa gtttgtcgtg
    13921 acggctgagg aatttgcaga gctccgtgac aatggacaaa ttttcagcca atacgttgac
    13981 tttaacggta aaccaagtat ggattctaag tacaatccga atggttctgt ccatgccatc
    14041 gaaggaatta ccagcaagaa tggtcaaatc atcggtaaga tgggccactc agaacgttat
    14101 gaggatggtc ttttccaaaa tatcccaggc aataaagacc aacacctgtt cgcatcagcg
    14161 gttaaacatt tcactggaaa ataagactta cagattttct aatagatagt atcagtaatg
    14221 taaaagtcat gtaaatctag ctcttgatga ttacaaatga aaattaggta taaaaaatga
    14281 catacgaagt aaaatctctt aatgaagaat gtggtgtttt cggtatttgg ggacatccag
    14341 atgctgctaa gttgacctat tttggactcc acagtcttca acaccgtggt caggaggggg
    14401 caggaatcct ctccaatgat caaggacaac tgaagcgcca tcgtgacatg gggcttttat
    14461 cagaagtttt cagaaatcca gccaatttgg ataaattgac aggagctggt gcgattgggc
    14521 atgtgcgtta tgcgactgct ggcgaagctt ctgttgataa catccagccc ttcctcttcc
    14581 gttttcacga tatgcagttt ggcttggctc ataatggaaa tctgaccaat gcagcctctc
    14641 tcaagaaaga actggaacaa agaggagcaa ttttcagcgc gacttcggac tctgaaatct
    14701 tggctcacct cattcgtcgt agtcataatc ctagcctgat gggcaaaatc aaggaagcgc
    14761 tcagccttgt caaaggtggt tttgcctata tcttgctgtt tgaggacaag ttgattgcgg
    14821 ctcttgaccc taatggcttt cgtccgcttt ctatcgggaa aatggccaac ggagcggtgg
    14881 ttgtttcctc tgaaacctgt gcttttgagg tcattggtgc cgagtggatt cgtgatttga
    14941 agccaggtga gattgtgatc attgatgacg agggcattca gtatgacagc tatacagatg
    15001 atactcagtt ggcgatttgt tctatggagt atatctactt tgctcgccct gattctaata
    15061 tccacggtgt caatgtccat acggcacgta agagaatggg agcgcaattg gcgcgagaat
    15121 ttaagcatga ggcagatatt gtagttggtg tgcccaattc ttccctaagc gcggctatgg
    15181 gatttgcgga agaatcaggc ttaccaaatg aaatgggtct gatcaaaaac caatacaccc
    15241 agcgaacttt tatccaaccg actcaagaat tgcgggagca aggagtgcgg atgaaactgt
    15301 ctgctgtttc gggtgttgtc aaaggcaaac gtgtggtcat ggtggatgat tccattgtac
    15361 gtggaacaac ctctcgtcgt atcgttcagc tcttgaaaga agcgggtgcg actgaggttc
    15421 acgttgccat tggaagtcct gcactagcgt atccatgttt ctacgggatt gatatccaga
    15481 cccgtcagga gctgattgca gccaatcata cggtcgaaga aactcgccaa atcattggtg
    15541 cggacagtct gacttatctt tcaattgatg gcttgattga gtcgattggt atcgaaacag
    15601 atgcgccgaa cggtggtctc tgtgtcgctt actttgacgg tgactaccca acgcctctct
    15661 atgactacga agaagactat cgtagaagtt tggaagaaaa gaccagtttt tacaagtagg
    15721 cgacagattc tccattaaag aaaaggaaaa aacaaatgac aaataaaaat gcatatgccc
    15781 agtcgggtgt ggatgttgaa gcgggttatg aagttgttga acggattaaa aagcacgtgg
    15841 cccgtacgga gcgtgcaggt gtcatgggag ctcttggtgg ctttggtggt atgtttgacc
    15901 tttccaagac tggggttaaa gaacccgtct tgatttcagg gactgacggt gtcggaacca
    15961 agctcatgtt ggctatcaag tacgacaagc acgataccat cgggcaggac tgtgtggcca
    16021 tgtgtgtcaa cgacatcatt gctgcaggtg cggaacccct ctattttctc gactacgtag
    16081 cgacagggaa gaatgaacca gctaagctag aacaagtggt tgctggtgtg gcagaaggtt
    16141 gtgtgcaggc tggtgctgcc ctcatcggtg gggaaacggc tgaaatgccg ggcatgtacg
    16201 gcgaagacga ctatgacttg gctggttttg cggtcggtgt ggctgaaaaa tctcaaatca
    16261 ttgacggttc aaaggtggta gagggagatg ttcttctcgg acttgcttca agtgggattc
    16321 actcaaatgg ttactctttg gttcgtcgtg tctttgcgga ttacacaggt gaggaagtcc
    16381 taccagaatt ggaaggcaag aaacttaagg aagttctact tgagccgact cgtatctatg
    16441 tcaaggctgt cttgccgctc atcaaagaag agttggtcaa cggcattgcc cacatcacag
    16501 gtggtggctt tatcgaaaat gtccctcgta tgtttgcaga tgacctagct gctgaaattg
    16561 atgaaagcaa agttccagtg cttccaattt tcaaagccct tgaaaaatat ggtcagatta
    16621 aacacgaaga aatgtttgaa atcttcaata tgggtgtggg acttatgttg gcggtcagcc
    16681 ctgaaaatgt agagcgtgta aaagaattgt tggatgaagc agtctatgaa attggtcgca
    16741 tcgtcaagaa agaaaacgaa agtgtcatta tcaaatgaaa aaaatagcgg tttttgcctc
    16801 tggtaatggc tcaaattttc aggtgattgc cgaagaattt ccagtggagt ttgtcttttc
    16861 agaccatcgt gatgcctatg tgcttgagcg tgcaaagcag ctcggcgttc tgtcctatgc
    16921 ttttgaactc aaggagtttg agagcaaggc agactacgaa gcagcccttg tcgaactctt
    16981 ggaagaacac cagattgcct tggtttgcct agcaggctac atgaaaatcg ttggaccaac
    17041 cttattgtcg gcttatgaag gtcggattgt caacattcat ccagcctact tgccagaatt
    17101 tccaggagct catgggattg aggatgcttg gaatgctggc gtgggtcagt ctggtgtgac
    17161 cattcactgg gtggattcgg gtgtggatac aggccaggtc atcaaacagg ttcgtgtgcc
    17221 acgactagct gatgatacca ttgacagatt tgaagctcgc atccatgaag cagagtacag
    17281 gttgtatccg gaagtagtga aggctctatt tacagattga ctttttgatg attcatatga
    17341 tatctttgat tttaaattgg agtcagtgtt tgttgaagac ggcttcaaac ggaggtattt
    17401 gtaatgttag aatctaaaaa aacaactcga tatgtatttt atgtctatct gatgttatta
    17461 acttggggaa tcttatttaa gtttgaaaca aatcctgaat ttatagcatt tttcttagct
    17521 ccaaggtata tcaattggat tccattttca gaaccactaa tagtcgatgg aaaaattgtt
    17581 tttgctgaaa tgttatttaa tctgattttc tttattccat taggtgtttg tttccctttg
    17641 ataaaaacta atttatctag tttaagaata gtcgggacag gtttcttgat tagtttattg
    17701 tttgagtgct tacagtatat tttagcaata ggtataacag atataacgga tttgacttta
    17761 aatacgctag gtgtctgtgt aggcttactg atttatcaaa tttttataag agtgttcaaa
    17821 tcacagacta gaaaatggat caatatctta ggtatgctta gccttggttt tgcttatctt
    17881 gttttactgt tactgcattt aattggtgtt taactaatga ttaaaaagga gaatataatg
    17941 actaaacgcg tcttaatcag cgtctcagac aaagcggaca ttgttgaatt tgcccaagaa
    18001 ctcaaaaaac ttggttggga gattatctcg acaggtggaa ctaaggttgc ccttgataat
    18061 gctggggtgg ataccattgc tatcgatgat gtgactggtt tcccagaaat gatggacggt
    18121 cgtgtgaaga ccctccaccc aaatatccac ggagggcttc tcgctcgtcg tgacttggat
    18181 agccacttgg aagcggctaa ggacaacaag attgagctca ttgaccttgt ggtggtcaac
    18241 ctttacccat ttaaggaaac tatccttaaa ccagatgtga cttatgatga tgcagttgaa
    18301 aatatcgata ttggtgggcc atctatgctt cgttcagcag cgaaaaatca tgccagtgtt
    18361 acagttgtgg tagatcctgc tgactacgct gtggttttgg acgaattggc agcaaacggc
    18421 gaaacctctt atgaaactcg ccaacgttta gcagccaaag tatttcgtca cacagcggct
    18481 tatgacgcct tgattgcaga atacttcaca gctcaagtgg gtgaaaacaa gcctgaaaaa
    18541 ctcactttga cttatgacct caagcaacca atgcgttacg gtgagaatcc tcaacaagac
    18601 gcggactttt accagaaagc tttgcctaca gactactcca ttgcttcagc caaacagctc
    18661 aacgggaaag aattgtcatt taataatatc cgtgatgcag atgctgctat ccgtatcatc
    18721 cgtgacttca aagatagtcc aaccgttgtg gctctcaaac acatgaatcc atgtggaatt
    18781 ggtcaagctg atgacatcga gactgcttgg gactacgctt atgagtctga cccagtgtct
    18841 atctttggtg ggattgtcgt cctcaaccgt gaggtggatg ctgcgacagc tgagaagatg
    18901 cacggcgttt tcctcgaaat catcattgca ccaagctata cggatgaagc gctagccatt
    18961 ttgatcaata aaaagaaaaa cttgcgtatc cttgccttgc catttaatgc tcaagaggct
    19021 agcgaagtgg aagcagaata cacaggtgta gtcggtggac ttctcgtgca aaatcaagac
    19081 gtggtcaagg aaagcccagc tgactggcaa gtggtgacta aacgtcagcc aactgagaca
    19141 gaagcgactg ctcttgagtt cgcttggaag gctatcaagt acgtcaaatc aaatggtatt
    19201 atcgtgacca acgaccacat gacacttggt gttggtccag gtcaaaccaa ccgtgtggct
    19261 tctgttcgcc ttgccattga ccaagccaaa gatcgtctgg acggggcggt ccttgcttca
    19321 gatgccttct tcccatttgc ggataacgtg gaagaaatcg ccaaagcagg aattaaggcc
    19381 atcatccagc ctggtggctc tgtccgtgac caagaatcca tcgaagcagc ggataaatac
    19441 ggcttgacta tggtctttac aggtgtgaga cattttagac attaagaaga taaaagggaa
    19501 gaaaacagtt tctttccttt tttggcttaa aatgctaact gaaacaagat taaaacgaac
    19561 ttttttgata taatgttggt aaataattcg caaaagaggt tgaggaatga aactgcttgt
    19621 tgtcggttct ggtggtcgtg agcatgcgat tgctaaaaag ttacttgaat caaaagacgt
    19681 ggaaaaagtc tttgtagctc ctgggaatga tgggatgact ctggatggtt tggaattggt
    19741 aaatatctct atttccgaac attctaaatt gattgacttc gcaaagacca atgatgttgc
    19801 ttggaccttt atcggtccag atgatgccct tgctgctggt atcgtggatg attttaacca
    19861 agctgggctt aaggcctttg gtccgactag ggctgcagcg gagctggagt ggtccaagga
    19921 ttttgccaag gaaatcatgg tcaaatatgg tgtttcgaca gcagcctatg gcacattttc
    19981 agatttcgag gaagcaaagg cctatatcga aaagcatggt gcgcctatcg tagtcaaggc
    20041 ggatggcttg gcgcttggga agggtgtcgt cgtttctgag acggttgagc aagcggtcga
    20101 agccgctcat gagatgcttt tggacaataa atttggtgac tcaggtgcgc gcgtggttat
    20161 tgaggaattc tttgaaggag aggaattttc actctttgcc tttgtcaatg gtgataagtt
    20221 ctacatcatg ccaacggctc aggaccacaa acgtgcctat gatggcgaca aagggcctaa
    20281 cacgggtggt atgggtgcct atgcgccagt tccacactta ccacagagtg tagttgatac
    20341 agcggttgac accattgtca agccagttct agaagggatg attaaagaag gtcgccctta
    20401 tctgggagtt ctttacgcag ggcttatcct gacagctgat ggaccgaaag tcattgagtt
    20461 caacgctcgg ttcggagatc cagaaactca gattatcttg cctcgcttaa cctctgactt
    20521 tgctcaaaat atcacagata tcctggatag caaggagcca aatatcacgt ggacggacaa
    20581 gggtgtgact ctgggtgtgg ttgtcgcatc caagggctac ccgctaaatt attcaaaggg
    20641 tgttgagttg ccagtcaaaa ccgatggcga catcattacc tactatgcag gggctaagtt
    20701 tgcggaaaat agcagagcac tgctctcaaa cggcggacga gtttatatgc tcgttaccac
    20761 agcagatacc gtcaaagaag cccaagccag catctaccaa gaactatccc aacaaaaaat
    20821 agaaggactc ttctaccgaa cagatatcgg aagcaaggca attaagtaaa gatataagaa
    20881 taacgcgccg tagtcgccaa acacgataat ggtcgtcgtg gtgaaaagac cagaacagtg
    20941 aatgttctgg tcagggggaa acttggagac cgtaggctca aagtttagga atgaaaccga
    21001 aggtttgctt ccgcctccat cacctaagac cattatcaaa aagaaaaata aaaattcaca
    21061 aaatacgtta atgatcgtat ggtttgcgag cgttagcgag ctaatataga acaatcaccg
    21121 ccgttgtgaa agaacgattg gatgataatc caatcgttca gggaaattgg aagaccttgg
    21181 gtttccaatt taggcatgag acacctttgg tggctgctgc cgtccctcac aagctaaggt
    21241 gattgttgaa aaagaggaaa aaggagaaga aatgaaacca gtaatttcca tcatcatggg
    21301 ctcaaaatcc gactgggcaa ccatgcaaaa aacagcagaa gtcctagacc gcttcggtgt
    21361 agcctacgaa aagaaagttg tttccgcaca ccgcacacca gacctcatgt tcaaacatgc
    21421 agaagaagcc cgtagtcgtg gcatcaagat catcatcgca ggtgctggtg gcgcagcgca
    21481 tttgccaggc atggtagctg ccaaaacaac ccttccagtc attggtgtgc cagtcaagtc
    21541 tcgtgctctt agtggagtgg attcactcta ttctatcgtt cagatgccgg gtggggtgcc
    21601 tgttgcgacc atggctatcg gtgaagctgg agcgactaac gcagctctct ttgccctccg
    21661 tctcctctct gtagaagata agtccattgc ggatgcactt gccaactttg ctgaagaaca
    21721 aggaaaaatc gcagaggagt cgtcaaatga gctcatctaa aacaatcgga attatcggtg
    21781 gcggtcaact gggtcagatg atggccattt ctgctatcta catgggccac aaggttatcg
    21841 cgctggatcc tgcggcggat tgcccggcct ctcgcgtggc ggaaatcatt gtggcacctt
    21901 ataacgatgt ggacgccctc cgtcagttgg cagaccgttg cgatgtcctc acttatgagt
    21961 ttgaaaatgt cgacgctgac ggtttggatg ccgttatcaa ggatggacaa ctccctcaag
    22021 gaacagatct gctccgcatt tcgcaaaatc gtatttttga aaaggacttt ttgtcaaaca
    22081 aggctcaagt cactgtggca ccctacaagg tcgtgacttc tagcctagac ttggcagata
    22141 tcgacttgtc gaaaaactat gtcctcaaga ctgcgactgg tggctacgat ggtcatggac
    22201 aaaaggttat tcgttcagaa gcagacttgg aagcagccta tgcgctagca gactcagcag
    22261 actgcgtctt ggaagaattt gtcaactttg accttgagat ttctgtcatc gtgtcaggaa
    22321 atggcaagga ggtgacgttt ttcccagttc aggaaaatat ccaccgcaac aatatcctgt
    22381 ctaagaccat cgtaccagcc cgcatttctg aaagtctagc agacaaggct aaagctatgg
    22441 cagtgcgaat cgcagaacaa ctcaacttgt ctggaactct ctgtgtggaa atgtttgcga
    22501 ctgatgatga cgttattgtc aatgaaatcg ccccacgacc acataactct gggcactatt
    22561 ctattgaagc ctgtgatttc tctcagtttg acacccatat tctgggtgtt ctcggagcac
    22621 cattaccagt catcaaactc catgcgccag ccgttatgct taatgtcctc ggtcagcatg
    22681 tcgaggctgc tgagcaatat gtgacagaaa attcaagcgc ccacctccac atgtatggta
    22741 aaatagaagc gaagcacaac cgcaagatgg gacatgtgac cttgtttagt gatgtaccgg
    22801 atagtgtgga tgagcttggg gaagggattg atttttagga caagtctatg atacaaatta
    22861 tcgttaatac atttattgaa aaggataaga ctggagcagt tgttgaagtg ttgtatgcca
    22921 gtgctgacca agataaggta caagctaaat atgaagaact agctgcacaa taccccgaaa
    22981 attatttagc tatctatgat gtaccgctgg atacggattt gaatacacta gatcattacc
    23041 cgtctgtgtt tattgaaaaa gaggagtttg agtagaaatc ttggtttacc tagatagctt
    23101 attcccaaca gcttaagaag aaaggaaaaa ttaacacatg atcaaccgtt actctcgccc
    23161 tgagatggcg aatatttgga gtgaagaaaa taaataccgt gcttggcttg aggtggaaat
    23221 cctctctgac gaggcatggg ctgagttggg ggaaatccct aaggaagatg tggctttgat
    23281 tcgcaagaag gcggactttg acatcgaccg tattttggaa attgagcagg agacgcgcca
    23341 cgatgtggtg gctttcacgc gtgcggtttc tgagactctt ggtgaagagc gcaagtgggt
    23401 tcactatggg ttaacttcta ccgacgtggt ggatactgct tatggttacc tctacaagca
    23461 ggccaacgac atcatccgtc gtgaccttga aaacttcact aatatcatcg ctgacaaggc
    23521 caaggagcac aagttcacca tcatgatggg gcgtactcat ggtgtgcacg ctgagccgac
    23581 aacctttggt cttaaattgg caacttggta cagcgaaatg aaacgcaata tcgagcgttt
    23641 cgagcatgca gctgctggtg tagaagctgg taagatttct ggtgcggttg ggaactttgc
    23701 caatatccca ccatttgtag aggagtatgt ctgcgataaa cttggcatcc gtgcccaaga
    23761 aatctctaca caagtccttc ctcgtgacct tcacgctgag tactttgcgg ttcttgccag
    23821 cattgcgact tcaatcgaac gtatggcgac tgagattcgt ggtctacaaa aatctgagca
    23881 acgcgaagta gaagagttct ttgctaaagg gcaaaaaggg tcttcagcaa tgcctcacaa
    23941 acgcaaccca atcggttctg aaaatatgac tggtctggcg cgtgtcattc gtggtcacat
    24001 gattacggct tatgaaaacg tcgctctctg gcacgaacgc gatatttctc actcatcagc
    24061 tgagcgtatc atcacaccag atacgaccat tttgattgac tacatgctca accgttttgg
    24121 aaatatcgtc aagaacttga cagtcttccc agaaaatatg atccgaaaca tgaactcgac
    24181 ttttggtctt atctttagcc aacgggctat gttgacattg attgaaaaag gcatgacccg
    24241 tgagcaagcc tatgacttgg tgcaaccaaa aacagcctac tcttgggaca accaagtaga
    24301 ctttaaacca cttcttgagg cagattcaga agtaacatca cgtctcactc aagaagaaat
    24361 cgatgaaatc ttcaacccag tttattacac caaacgagtg gatgatatct ttgaacgtct
    24421 tggactaggt gattaattaa aaaataaaca gcgagcttca atctcgctgt ttatttttta
    24481 tcgaaaagac ttagtcttct tttcttttag tgagtccata ggctgctagt gtggccatga
    24541 gtcctgcgac tactagtcct gcagaatcgt gagttcctgt ttcaggaagt tttttctcta
    24601 ttaccacagg agctggatct tgaggaagag ctttgctttc ctcagcagga gcagttgatg
    24661 gagctggttg gcttgggatt tctagttttg gtttttcttc agcaatagcg gcttgtccgt
    24721 tttcatcgcc tacatgtgtt accatagttc cgacttcgac tatttgagta acggcttcct
    24781 gtgctacgac actatttaca agtgttttca cttccttacc atcggcagaa gtgctcacag
    24841 agtagaagtt gctacgatgt ccattgacgc ccttagtaat gacttgtgtt tttcctttga
    24901 gtaagagtgg attttcacga gtcactgtgg taaatggaat ttcttctttt tggatatcca
    24961 gtctaggttt tacctcagta gttggtgcaa gaccactttc atcacccttg tgagttacag
    25021 gagcgccaac ttcaaccact tggtttataa cttctttggt tacctggcta tcaaggactg
    25081 tttctgttgt ttttccattt tcagtgagta cagagatgta atgagttcgc tcacctttga
    25141 ctcctgctgt gataatattt tcctgaccag ctgggaggtt aggattttct ttcttgataa
    25201 cttcaaatgg aatttcttca gttcttgtga tgagttctgg tctggtttca acattggcag
    25261 ccacttcatt ttcatccagg cttcctgaat gagttgcagc tggtttgagg ccttgaagag
    25321 cggcttttag gttggctaca agtgtgtcaa gctcagcttg tttattacgg ttgaggttgt
    25381 aatttagagc tgttttagct gcgtcaaggg cctcaagact ttctttacta tatccttcta
    25441 agtttgtagg aattttagct aattcttcgc ggagagcatt ataattagca cggaagtagt
    25501 ctttgttgtg gtctgcaaag gcagtcatga gttcaaagat ttcctcttcc ttgtattcag
    25561 cgcttggtct atctgcccag attgaaagca tacttccgac tgttggaaga tctacttcag
    25621 gatatttggt agaagctagt tgattgaatg gtgtttttcc agtattctca atagctttct
    25681 tgaggaaacc accaccatct tctggttttt gaccaagaat gtagtaccag tcaccgttgg
    25741 tattcaagaa tttatagcct ttgcttgcta ggtattgagg tgatgcgagg ttatatcccc
    25801 accagccttt agaccagtaa gaaatcaaga catctttgtc aaactgaaca tcgtccttgt
    25861 cttcatagta gaagccatcg ttgaaggcca ttggttgaag ccctctttct ttggccatag
    25921 ctgcgagggt gttggcatat tcggcaaatt tgccatagag ttgataccac ttgaggtagt
    25981 accagccttg ggcactagtc gcatcgttgg cgtattcgtc agtaccaaag ttgaaaatct
    26041 ttgttttacc tgcaaagaag tccatgtatt taccgatgag ggcttttaca aagttcatcg
    26101 cttcttcgtt tttcaagtcc atagttgttt ttgaaacttt atcaaagtgg gcttgaggat
    26161 ttttaatacc taatttttcc atggcaacca gcatagcatc catgtgacct ggactgttaa
    26221 tagctgggat gagaccgatg tccttagatt tagcgtattc aattagctct gttacttctg
    26281 cctgtgttag tgcagtaccg tttggatcgt cgtagtaagc tttagttcct tcgataatag
    26341 cttttttaac gtcatcacta gcataggttt ttccgttggc agtaatggtc atatcatcga
    26401 gtagaaagcg aagtccgtca tttcctagaa ggagatggac atcagaatat ccgagctcac
    26461 tggccttgtc tacgatgcgt ttgagctggt tcagagtaaa gtatttgcgt ccagcatcga
    26521 ttgagattac cttgtttttg gcaagttttt caacctcacg tttagcttct tcttcttttt
    26581 gagcttcagg cgtgagggtc aagttgttga cagtttcttg aagtttagca atggcttgat
    26641 caatcgtatc ttgttgggca cggctaaggt tgctatcgag agagcgaata gctttttcag
    26701 cttcttttac ggccgcgacg ctttctgcag tataacggtt caggtctttt ggtacctcgt
    26761 taagtgtttg ctctgcagat tcataatcag ctgcgaagta ttcagcgttg gcatttgcaa
    26821 aatgacgcat gagtttgaag aggcgtgatg gtgaataacg tgcagatgga gtgtcagccc
    26881 aagcagctac catactaccg atgattggga tatcagctcc ttctgttttt ggtacagaag
    26941 tgattggtgt gtttttaata ccattgagcc cctgatcgag attgtaccag ccttggccat
    27001 cagcgtttcg tccaagaacg tagtaccaag catcattggt attaaggatt tggtgacctt
    27061 tttcagctag tagtttagaa gaagcgacat cgtagcctcc ccaaccacca gtccacatag
    27121 aaacgatgat gtctttgtca aaactaccaa agcttgtgtc gctattgtag tagataccgt
    27181 cgttaaaggc cattggtttg agaccgtgcg attttacaat acgagcgagg tcattggcgt
    27241 aggcaataaa tttttcatag ccttttacag ggtagccttc gtttggatag tatttatcag
    27301 cttgaagcac actccaacct ttagcatctg tcgcatcatt ggcatattca tcaagtccga
    27361 tgttgaagat ttcagtcttt ttcgcgaaat aagcagcata cttgtcgata agggcttttg
    27421 taaaagcgac agcttgttcg ttgtcaagat tgacagtacg ggctgattcc ttcccaaaat
    27481 agctaaagtt agggttttgg attcccaatt ctttcatggc attgagaatc gcatccatgt
    27541 gaccaggact atttactgtc ggaatgagac cgataccttt atctttggca tagttaatca
    27601 gatctgtcat ttgactttct gttaagtgat tgccgtttgg atcgttgtaa taatcatttg
    27661 tacctttttc aatggcgcgt ttgacatcgt cactggcata ggtcttgccg ttagctgtga
    27721 tgctcatatc gtccaacatg aaacggagtc catcatttcc gactaatagg tgtaaatcag
    27781 tgtagccata atgtttcgct ttatcgatga tttccttgag ctgttctggt gagaaatatt
    27841 tacgtccagc atcaatagaa acaattttct ttttcgctag tttttcattt acagttgcag
    27901 cacgttcctt tcctgcctct gtttccggtt tgtcatcctc tgctttcgct tcatcttttt
    27961 tagctggttt atccttgtca gtcttgtctg tatttgactc tttagaatca acctctttcg
    28021 cttcttcctt tttagggcta gcttcttctg cctttttatt agcagtttct ttttcagcag
    28081 aagttggagt taccacttct gctttatcac taggagttga actaacttcc tcttgtggtt
    28141 tttcttctgt ttttggaaga ctagctacct tatcagtagc tggagtttct gtttctacag
    28201 tttttggagc ttctggttga agctctgctt taggtgtttc ctcagtccga ttttcggatg
    28261 attgagggga atcagaaacc gtatggatgg tcggttggtt ttctgtagta gtaggagtaa
    28321 ctccatcggc tgcaacagtc tgtgcttgga aggcaaatcc aattagaaca gaagctgctc
    28381 ctacagcgta tttacgaata gaaaaacgct gttgtttttc atgtttcatt gcaaaacctc
    28441 ctgattgcat tgttatattg atagcgatta tataaatcaa cgcctttatt ttatttctta
    28501 tattaacgag agtcaagagg agatgacaaa aaactataat aagtataaaa aaatataaaa
    28561 tttaaactta agatttcaga ttggtcggaa aaaatacgta tatatatcta gtataatttt
    28621 tggttctatt tctataaaat attccacaaa ttatagaatt ttccaaaaat aggtaagcgc
    28681 tacctttttg gtgtggtata ataagcatag aaaaagccca agcgattagc tcaggctttc
    28741 ttcttagtga tcacggtcac atgagataaa tttaatcttg tagtaatcag atcgtttgta
    28801 agtttcactg tattctaaaa cttggccagt tgattcgagt ttggtgattt tagtttgtag
    28861 gacagtaggg aattgttcat cgactccgag gactgaagcc gcatgttctg gagttggaaa
    28921 gactatttcg ttgatttctt caaagtgttc atcattcatg tgaatgtggt agtctaactt
    28981 gaaacgatta tagatagaac tatagtattc aaggtttgga taatttgcgt tgatatattg
    29041 ttctgggatg taggatgtat ggtagatata aacgacaccg tttgattcgc ggatacgttc
    29101 aatcttgtag tagaattgat cgccgcgtag acccaatttt tccaagtaaa caagcttgtt
    29161 tccgcgttca attgaaagaa cagttacctt atcatcttta gcattgaaga gttcaatatc
    29221 tgaaaactct acaagcttgt gtttgcgtgc acgtgaaacg aaggttcctt ttccttgttg
    29281 gcggacaata tagccatctt tggcaaggtc gtttaaggcg cgaacaactg tgatagagct
    29341 gacatcgtac attgaaatga gttctgcttc agtgtaaaat ttatctccac tgctaaactg
    29401 cccagagatg attttatttt ttaattcgtc ttttatgtat tgatatttgg gaattgccat
    29461 atttttacct ctattttcct tctccatagg aaattttacc ataaaagcga aaaaaatagt
    29521 agtcttttga ataaaaaatt agaataatag tttgaaaaat taagcgatat agggattgct
    29581 catattttat caatgtattc tatacaaaat tattttaggt cccatattcc gaatttaaag
    29641 agcgtttgaa atgggtctaa aaatgtttga aactaattga atgtgtgtat aatagtaaaa
    29701 atgcagtaaa tatcccgaca atttctattg acaattcaaa cagattggtt tataattaat
    29761 ataacaacaa atgaaagcgc aaactttcgc ggtcggaagg tagttttatg acacgatttg
    29821 agatacgaga tgatttctat ctcgatggaa aatcatttaa gattttatct ggtgccattc
    29881 attattttag ggttcctcca gaggattggt atcattcgct ctataacttg aaggctcttg
    29941 gttttaatac ggtagagact tatgttgctt ggaatttaca cgagcctcgt gaaggtgagt
    30001 ttcattttga aggtgatctg gatttagaga aatttctcca aatagcgcag gatttgggtc
    30061 tctacgcaat tgtgcgtccg tctccattta tctgtgcgga atgggaattc ggtggcttac
    30121 cagcttggct cttgaccaag aacatgcgaa ttcgctcatc cgacccagta tatatcgagg
    30181 cagttggtcg ctactatgat cagttattgc caagactggt gcctcgtttg ttggacaatg
    30241 gtggcaatat tctcatgatg caggttgaaa atgagtatgg ttcttacgga gaagataagg
    30301 cttacctgag agcgattcga cagctaatgg aagagtgtgg cgtaacctgt cccctcttta
    30361 catcagatgg tccatggcga gctactctga aagctggaac cttaattgaa gaggacctct
    30421 ttgtaacagg aaactttggt tctaaggcac cttacaactt ttcgcagatg caggaattct
    30481 ttgatgaaca tggtaagaaa tggccactca tgtgtatgga gttctgggat ggttggttca
    30541 atcgctggaa agaaccgatt atcacacggg atcctaagga attggcagat gcagttcgag
    30601 aggttttgga acaaggctct atcaatcttt acatgttcca cggtggtaca aactttggtt
    30661 tcatgaatgg ttgctcagct cgaggaactt tggacctgcc acaagttacg tcttatgatt
    30721 acgatgccct tctggatgaa gaaggaaatc caactgctaa atatcttgca gtcaagaaga
    30781 tgatggcaac acatttttca gagtatccgc agttggaacc actctacaaa gagagtatgg
    30841 agttggatgc tattccacta gttgaaaaag tttctttgtt tgaaacctta gatagcttgt
    30901 caagtcctgt agaaagtctc tatcctcaaa agatggagga gctgggacaa agttatggct
    30961 acctacttta tcgaacagaa acaaactggg atgcagaaga agaaagactt cgtatcattg
    31021 atggtcgaga tagggcccag ctgtatgtcg atggtcagtg ggttaaaact caatatcaga
    31081 cagagattgg ggaagatatt ttttatcaag gtaaaaagaa agggctatct aggttagata
    31141 tcttgataga aaatatgggg cgtgtcaact atgggcataa gttcttagcg gatacgcaac
    31201 gtaagggaat tcggacaggg gtctgtaagg atctgcattt cttactaaac tggaaacact
    31261 atccactccc actagacaat cctgagaaaa ttgatttttc aaaaggatgg actcaaggac
    31321 aaccagcctt ttacgcttat gactttacag tcgaagagcc aaaagatact tacctagact
    31381 tgtctgagtt tggtaagggg gttgcctttg tcaatgggca gaatctagga cgtttttgga
    31441 acgttggccc aactctctca ctttatatcc ctcatagcta tctcaaggaa ggtgccaacc
    31501 gcatcattat ctttgaaaca gaaggtcaat ataaagaaga gattcattta actcgtaaac
    31561 ctacactaaa acatataaag ggggaaaact tatgacaatt gtaggatgcc gtattgatgg
    31621 acgtttgatc cacggacaag tagccaatct ttgggctgga aaactaaatg tttcacgcat
    31681 tatggttgta gacgacgaag ttgtcaacaa cgatattgaa aagagtggtt tgaaacttgc
    31741 gacaccacca ggtgtgaaat tgagtatttt gccagttgag aaagctgcag ccaatattct
    31801 tgctggtaaa tacgatagcc aacgtctctt tatcgtggct cgtaaaccag accgcttcct
    31861 tggtttggta gaagcaggtg taccacttga aacccttaat gttgggaata tgtctcaaac
    31921 accagaaaca cgttctatta cacgttctat caacgtagta gacaaggatg tggaagactt
    31981 ccacaaactg gcagaaaaag gtgttaaact tactgctcag atggttccaa atgatccaat
    32041 ttcagacttt ttgagcttat taaaatagga aaaaaatttt taggaggtca ttgttatgat
    32101 acaatggtgg caaattttac ttctcacttt gtactcagct tatcaaatct gtgatgagtt
    32161 gacgatcgtt tcatctgcag gttctcctgt atttgctggt ttcattactg gtttaatcat
    32221 gggagatgtg actactggtt tacttatcgg tggtaacttg caactgttcg ttcttggggt
    32281 tggtaccttc ggtggtgctt ctcgtatcga cgcaacttct ggtgcggttc ttgcgacagc
    32341 cttctctgtt tcacaaggaa ttgatgcacc gcttgccatt actacaatcg ctgtaccagt
    32401 agcagctctc ttgacttact tcgacgttct tggtcgtatg actactacct tcttcgctca
    32461 ccgtgtggat gctgcaatcg aacgctttga ctataaaggt attgaacgca actacttgct
    32521 tggtgcgatt ccgtgggctc tatctcgtgc ccttccagtc ttctttgccc ttgcttttgg
    32581 tggtgccttt gtacaatcag tagtagactt cgttgaagcc tacaaatggg ttgcagatgg
    32641 cttgacactc gcaggacgta tgcttccagg tcttggattt gcaatcttgc ttcgttacct
    32701 tccagttaaa cgtaaccttc actaccttgc tatgggattt ggtttgacag ctatgttgac
    32761 tgttctttac tcatatgtaa caggtcttgg tggcgctgtt gctggtatcg taggtactct
    32821 tcctgctgaa gttgctgaaa aaattggttt cgtgaacaac ttcaaaggtt tgtctatgat
    32881 tggtatttct atcgtaggta ttttccttgc agtgcttcac ttcaaaaata gccaaaaagt
    32941 agctgtagca gcaccttcta caccatcaga aagtggggaa atcgaagatg acgaattcta
    33001 attacaaact tacaaaagaa gattttaatc aaatcaacaa acgtagcttg tttactttcc
    33061 aattaggttg gaactacgaa cgtatgcaag cttctggtta cctttacatg atcttgcctc
    33121 agttgcgtaa aatgtatggt gatggaactc ctgaattgaa agaaatgatg aaagttcata
    33181 ctcaattctt caatacttca ccattcttcc ataccattat cgctggtttt gaccttgcca
    33241 tggaagaaaa agatggtgta ggttcaaaag acgctgttaa cggtatcaag acaggtttga
    33301 tgggaccatt cgctcctctt ggggatacaa tctttggttc acttgtacct gctatcatgg
    33361 ggtcagtcgc agcaactatg gctatcgctg gccaaccttg ggggatcttc ctttggattg
    33421 cagttgcagt agcgtatgac atcttccgtt ggaaacagtt ggaatttgct tacaaagaag
    33481 gggttaacct tatcaacaac atgcaaagta ccttgacagc tttgattgac gctgcatctg
    33541 tacttggtgt cttcatgatg ggtgctcttg tagcaacagt gattaacttt gaaatttctt
    33601 acaagttgcc aatcggtgaa aagatgattg atttccaaga catcttgaac caaatcttcc
    33661 cacgtttgct tccagcaatc tttactgcct ttatcttctg gttgcttggt aaaaaaggta
    33721 tgaactctac taaagctatc ggtattatta tcgtacttgc tttggctctt tctgcccttg
    33781 gtcactttgc acttggaatg taattcctta tgactaaatc attaattttg gtgagccatg
    33841 gtcgcttctg tgaggagctt agaggtagca cagaaatgat tatgggccca caagacaaca
    33901 tttacacagt agctcttctt ccagaagatg gcccagaaga atttactgct aaatttgaag
    33961 ctgttattga aggattggat gatttcctag tctttgcgga tcttctcggt gggacacctt
    34021 gtaatgtggt gagtcgcttg atcatggaag gtcgtgatat tgacctttac gcagggatga
    34081 atcttccaat ggtgattgaa tttatcaatg cgagccttac aggcgcagat gcggactaca
    34141 agagccgtgc tgcagaaagc attgtgaaag ttaatgacct gttagcgggc ttcgatgatg
    34201 acgaagatga ataatactct tcgaaaatct cttcaaacta cgtcaacgtc gccttgccgt
    34261 aggtatatgt tactgacttc gtcagtctta tccggcaacc tcaaaacggt gttttgagct
    34321 gacttcgtca gtcttatccg gcaacctcaa agcagtgctt tgagcagcct gcggctagtt
    34381 tcctacagat tttagttgga actcgattca attcatgtga caacgtgaaa atcgttagag
    34441 cattttatat agaatataca tgggaatgga gcttactccc attcccatat ttaatagaaa
    34501 aagaggaact caatgctaca ttatacaaaa gaagacttgc tcgaattggg tgcagaaatc
    34561 actacgcgtg aaatctacca acagcctgat gtatggagag aagcttttga attttatcaa
    34621 gcaaaacgtg aagaaattgc agcctttcta caagaaatcg ctgataaaca tgactatatt
    34681 aaggttatct tgacaggtgc tgggacttct gcttatgtgg gagatacctt gctaccttac
    34741 tttaaggaag tctatgacga acgcaaatgg aatttcaatg ctattgcgac aacagatatc
    34801 gttgccaaac cagcaaccta tttgaaaaaa gatgtggcaa ctgtccttgt gtcttttgct
    34861 cgtagtggga actcgcctga aagtgtggcg actgttgatt tggccaaatc cttggtggat
    34921 gagctttatc aagtgacgat tacttgtgca gcagatggta aattggctct tcaagctcac
    34981 ggtgatgacc gtaatctctt gctcttgcaa ccagctgtct ctaatgatgc tggatttgcc
    35041 atgacttcta gctttacgtc tatgatgttg acaactctct tggtctttga tcctacagaa
    35101 tttgctgtta agtctgaacg ttttgaagtt gtatctagtc ttgcccgtaa agttttagac
    35161 aaggcagaag atgtcaaaga gctcgttgat ttagacttta accgtgtcat ctatctaggc
    35221 gctggtcctt tctttggact tgctcatgaa gctcagctca agattttgga attaactgct
    35281 ggtcaagttg cgaccatgta tgaaagccca gttggcttcc gtcacggtcc aaaatctctt
    35341 atcaacgaca atacagttgt tttggtcttt ggtacaacga cggactacac tcgtaagtac
    35401 gacttggact tggttcgtga agttgctggt gaccagattg ctcgtcgtgt tgtgcttttg
    35461 agtgatcaag cttttggtct tgaaaatgtc aaagaagtgg tccttggttg tggcggtgtc
    35521 ttgaatgata tttaccgtgt cttcccttac atcgtttatg cccaactctt tgccctattg
    35581 acttcactca aggtagaaaa taaaccagat acaccgtctc ctacaggtac agtaaaccgt
    35641 gtagtacaag gtgtcataat tcacgaatat caaaagtaag acagtgttta tgaattcttg
    35701 acaagaggat ttgtaaatta tcagataaac catagattgt cagtacgctt tctatggttt
    35761 gtttgcttga gagaaatagt aaaaggagaa cagaatgaaa gcatacacag agcgtgtatt
    35821 tggaaatgtt gagggtgagg atgtcttggc ctatcgattt gagacagacg gtggctacca
    35881 acttgaggtt atgacttatg gtgcgactat cttgcgctat gtcgcacctg acaaggctgg
    35941 aaattttgcc aatgttatct tgggatttga tgactttgat agttatgtag gcaatagtcc
    36001 caagcatgga gcaagtgtag gtcctgtagc gggtcgtatt gcaggtgcga cctttgagct
    36061 caatggtaag acctatgacc ttgaggttaa taatgctagc aactgtaatc acagtggttc
    36121 aactggttgg gattccagct tgtttgaagt tgaagaagta agcgatcatg gcttgactct
    36181 ctacacagag cgtacagatg ggacaggagg gttccctgga aatctcaaga tttggatcag
    36241 ttatcacttg gaagaaactg gtgcctatga aatcagctac aaggtaacga ccgatcagga
    36301 tacgctggtc aatccaacca accacagcta tttcaacttg tctggtgatt tcacgcagac
    36361 gattgaccgt catgtcttcc aactaaacac agagggcatt tactcaatcg ctcctgacgg
    36421 tgttcctgcc aaaactccag aagccaaccg tgatgtggtc aaacacatct acaatggtgc
    36481 cttgttgaag gatatctttg cagaagaaga tgagcaaatc cagctggcat caggtttgga
    36541 tcatccattt gcccttcctg caggccatga caatgctgga ttcctttatg accaaaattc
    36601 aggtcgcttc ctgcttttca agacagaagc tccttgcttt gtggtctaca cagcaaactt
    36661 tgtggatgaa agtgtcatca taggaggtca gccaatgcta cagcacaatg ggattgctct
    36721 tgaagcgcaa gctttaccag atgccattca cagtgacctt aaaggccaag tcattcttaa
    36781 agctggtcaa accttcacca gtaagacacg ttatgaactt gttgtgaaat aaaaaaagct
    36841 ggtcaaaaag tctttaaaat taaaataacg catattgtca ggtgatgaaa agtttgataa
    36901 tatgcgtttt attatgaaat gatttacttt atattatcct gaaatggtgt tatttttgag
    36961 ttatctggct tgactttctt gatggaaatt atataatagt tgtaacaatg ataattacaa
    37021 ctagaaaaga ggaccattta tgacctatga atacaagagt cacatttatt tggcagagac
    37081 agctttaaat gtaaaggatt tggccagtca aacagccttt tatcagcaag ttattggttt
    37141 agaaatctta tctcaaactg agacagagtc cattctaggc cttggtggaa aagtcttggt
    37201 acagctgatt caagcacaag agagcggaga agtgagggaa tattatggtc tttaccattt
    37261 ggccattctc ttgcccacac gcaaggcttt agctgatgtc ttgaaacacc tgacagattt
    37321 acaaattcct cttgtcggcg gtgcagacca tggttacagt gaagctattt acttggaaga
    37381 tttggaggga aatggcattg aactctatcg agataagcca gtttccacat gggatattcg
    37441 agaagatgga cgcattatcg gagtgacaga ggctcttgcg gcgcaggaca tttatgagtt
    37501 gggggaaaga gtagagccct ttatcctggc agaaggtacg agaatggggc atattcatct
    37561 ttccgtcaag gatagtcgaa agtccagcca gttttatcaa aaggtgttag ggctagagga
    37621 taaattcagt gtgcctagcg ctagttggat tgcggctgga gattaccatc atcatttagc
    37681 agttaacgaa tggggaggaa aaggtctggc ttcgcgtaag caaggcttac caggtttagc
    37741 ctactatgtc atcgaagtcg cacacaaaaa agaactatta acgattgccc aacgagcaca
    37801 agaagttgac gcaccaatca aatggatgac atcgagccaa ttggaaatca cagactcaga
    37861 tggcatcgtg acccgtattc gtttagcaag gtaaaattag gaatttttaa taagttataa
    37921 gtattgctag tttgcttttt gaacggtctt tggtaacaga actgcgtgag ctggatgggc
    37981 gagaattttg acaaagaagc tgattagaga tataatgaag aaaaatcgag caaggaaaaa
    38041 gaaatgacaa attcaaagta tattacttgt ttgaaacgtt cagagggcca gttgtgtggg
    38101 attcaaaaga tgattgaagg agatcgtgac tgtgctgata ttgtgacgca actgacagca
    38161 gtgagatcta gtgtagagcg cgtgattgag atgataatta ccgaaaatct tactgaatgt
    38221 atcaatcagc cactagatga ttctgaagct caaaaggaac gcttagaaaa ggctatccga
    38281 tacttgatta aacggaaata aatgaatgtt ttgagacgat atgtgcaaag gtctattaac
    38341 tattagaata gtttaatggg agtcaaaaga agttgtaaaa aatctttaaa attaaaaaaa
    38401 cgcatagtat caggtattga aatgtactga ccccaaaaag ttagattttt tctgtctaac
    38461 ttttggggtg cagttcataa gaaccttggt aatatgcgtt ttattatggg gagatttata
    38521 cttttcgaaa atctcttcaa accaggtcag cttcaccttg ccgta
//
LOCUS       DAVBEO010000014        37452 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 009
            SAMEA1678075-rid20185393.denovo.014, whole genome shotgun sequence.
ACCESSION   DAVBEO010000014 DAVBEO010000000
VERSION     DAVBEO010000014.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678075
            Sequence Read Archive: ERR226392
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 37452)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 37452)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980207.1
            Genome Coverage       :: 150x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:50:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 72 of 147
            Pseudo Genes (incomplete)         :: 72 of 147
            Pseudo Genes (internal stop)      :: 42 of 147
            Pseudo Genes (multiple problems)  :: 32 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..37452
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678075-rid20185393.denovo.014"
                     /strain="KS 009"
                     /db_xref="taxon:1313"
     gene            complement(<1..777)
                     /locus_tag="VQ543_000760"
     CDS             complement(<1..777)
                     /locus_tag="VQ543_000760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HET2611512.1"
                     /translation="MSKETVVYTKRREKIKDNILGYSFLAPALILLGIFLVIPVGMVI
                     YYAFTDYYLLTPDERKFVGLENFIRLTKDPIFLKSFLNTLKFVVWIIPVQLGAALGMA
                     LIVNKKRKGNMFFKVAFFAPVVMSLVVISILWLYLLNPNSGLLNAILNKVGIASQPFL
                     TSPKQAMYAIVFVSAWQGAGYQMLLFLGGMQNIPQDVYEAAELDGFSKWAQFRYITMP
                     LLKPTALFVLLTTLISAFKLIVQPMVMTQGGPLNSTITMVY"
     gene            complement(873..2183)
                     /locus_tag="VQ543_000761"
     CDS             complement(873..2183)
                     /locus_tag="VQ543_000761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HET2611513.1"
                     /translation="MRKGTMLSVVAGLSLAILAGCSGGTNSKQASSSNDIKVWVQFSD
                     ETNEGKAWQKVVDNFNQSGKSKYKVVTEYIPRSGSGGGYEDKVNAAITTNSLPDVITL
                     DGPNTAAYAKSKVITPLDDYLKDNNMDDVLDSIKQQGTYNGKFYAFGFSESNVGVYYN
                     KKMFKEAGIAESELPTLEKPWTWDEFNTIAKKLKDHYNKPAIDFRINSNDEMLPYAYM
                     PLIWSNNGSVVNEDGTKAEGYFNSKESVEAVQFIQNLVKEGYTTVSPVEKGFETGEYP
                     MLLSGSWTIADMNTNYKDIDFGILPYPVSSKTKKLVSPSGSWQLAVTTKSDKKEAASE
                     FVKFATNTESSEIISLGNSVLPIRKSTIENIKDKVSEPMRFLMEQNSKTAHARPVVVA
                     YPQVSRAFQQAMQDISYYEENPNVQKVLDTRTKEMQTAIDQSLK"
     gene            complement(2310..3305)
                     /locus_tag="VQ543_000762"
     CDS             complement(2310..3305)
                     /locus_tag="VQ543_000762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000230211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HET2611514.1"
                     /translation="MVEQRKSITMKDVALEAGVSVGTVSRVINKEKGIKEVTLRKVQR
                     AIKTLDYIPDNYARGMKKNRTETIALIIPSIWHPFFSEFAYHVEKELLKYNYKLFICN
                     ADSDSQNEIEYIEMLKQNKVDGIIGITYSDIDKYILSDLPFVSIDRHFSENVCYVTSA
                     NYKGGQTAAEELVRRDNKHLAFIGSINMYENETILRSKGFREKAKELGVDVYNFEMKE
                     PLINPEDQIRIFLQSHKEIDGIFTINDMMALRVISVMKELGKIAPDDYQIIGFDGLKT
                     SVDQSYLVSTIVQDIGMMAKESVAMILKMIKREEILEKRIVIPTYFGGDKTTKKI"
     gene            complement(3667..5148)
                     /locus_tag="VQ543_000763"
     CDS             complement(3667..5148)
                     /locus_tag="VQ543_000763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001205273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HET2611515.1"
                     /translation="MRDLLSKKSHRQLELLELLFEHKRWFHRSELAELLNCTERAVKD
                     DLSHVKSAFPDLIFHSSTNGIRIINTDDSDIEMVYHHFFKHSTHFSILEFIFFNEGCQ
                     AESICKEFYISSSSLYRIISQINKVIKRQFQFEVSLTPVQIIGNERDIRYFFAQYFSE
                     KYYFLEWPFENFSSEPLSQLLELVYKETSFPMNLSTHRMLKLLLVTNLYRIKFGHFME
                     VDKDSFNDQSLDFLMQAEGIEGVAQSFESEYNISLDEEVVCQLFVSYFQKMFFIDESL
                     FMKCVKKDSYVEKSYHLLSDFIDQISVKYQIEMENKDNLIWHLHNTAHLYRQELFTEF
                     ILFDQKGNTIRNFQNIFPKFVSDIKKELSHYLETLEVCSSSMMVNHLSYTFITHTKHL
                     VINLLQNQPKLKVLVMSNFDQYHAKFVAETLSYYCSNNFELEVWTELELSKESLEDSS
                     YDIIISNFIIPPIENKRLIYSNNINTVSLIYLLNAMMFIRLDE"
     gene            5591..5755
                     /locus_tag="VQ543_000764"
     CDS             5591..5755
                     /locus_tag="VQ543_000764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HET2611516.1"
                     /translation="MGIIANVFAGLVGAYAGQSLLGSWGPSIAGMALLPSIVGAAIVI
                     TVVSFFTGRK"
     gene            5839..6405
                     /gene="amaP"
                     /locus_tag="VQ543_000765"
     CDS             5839..6405
                     /gene="amaP"
                     /locus_tag="VQ543_000765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000030212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HET2611517.1"
                     /translation="MSKAKKICFIIFCILILTIFLPVLIDYHQVSDLGIHLLSWRQNS
                     VVEFYLARYVFWGTVVLSTLVLLSILVVMFYPKRYLEIQLETKNDTLKLKNSAIEGFV
                     RSLVSDHRLIKNPTVHVNLRKNKCFVHVEGKILPSDNIADRCQIIQNEITNGLKQFFG
                     IERQVKLEVAVKNYQPKPQNKKTVSRVK"
     gene            6417..6587
                     /locus_tag="VQ543_000766"
     CDS             6417..6587
                     /locus_tag="VQ543_000766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HET2611518.1"
                     /translation="MEWLKQYRYPIIAGLIGVFLACLIVSFGFFKTIFVLILGALGVA
                     AGLYIEKNYIDK"
     gene            6626..7234
                     /locus_tag="VQ543_000767"
     CDS             6626..7234
                     /locus_tag="VQ543_000767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000064115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HET2611519.1"
                     /translation="MSNEKNTNTNVEKKDATVVAHEIKGELTYEDKVIQKIIGLSLEN
                     VSGLLGIDGGFFSNLKEKIVNSDDVTSGVNVEVGKTQVAVDLNVIVEYQKNVPALYSE
                     IREIVSSEVAKMTDLEIVEINVNVVDIKTKEQHEADSVSLQDRVSDVAESTGEFTSEQ
                     FEKAKSGLGSGFSTVQEKVSEGVEAVKGAANGVVSHENTRVN"
     gene            7265..7468
                     /locus_tag="VQ543_000768"
     CDS             7265..7468
                     /locus_tag="VQ543_000768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HET2611520.1"
                     /translation="MSVEEKLNQAKGSIKEGVGKAIGDEKMEKEGAAEKVVSKVKEVA
                     EDAKDAVEGAVEGVKNMLSGDDK"
     gene            complement(7578..7856)
                     /locus_tag="VQ543_000769"
                     /pseudo
     CDS             complement(7578..7856)
                     /locus_tag="VQ543_000769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007895264.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            8054..8341
                     /locus_tag="VQ543_000770"
     CDS             8054..8341
                     /locus_tag="VQ543_000770"
                     /inference="COORDINATES: protein motif:HMM:NF033563.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HET2611521.1"
                     /translation="MIVSLKTKSRKAKDMAESIQGWLAQFLVNLFKSITFDCGKEFSK
                     WKDISNHHDSESFFANLGCSRQRRLNEHSNRLLRCHDLPKQTDFNEVSQEF"
     gene            complement(8619..9389)
                     /locus_tag="VQ543_000771"
     CDS             complement(8619..9389)
                     /locus_tag="VQ543_000771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HET2611522.1"
                     /translation="MVEIIYFLIIIIASGLGSISGMGGGIIIKPLMDSFGYHSVSDIA
                     FYSSFSVFIMAIISTIKRFSQSKEIKWRLIFTVSFSSVLGGFLGHLIFQVLLSQLSVR
                     LVSIVQMILLFVMLLVSFVLTDFKKTYQFDKIGFYMICGLLLGLISSFLGIGGGPLNV
                     SLLMVFFSISIKEATMYSLAIIFFSQLSHLATIVVVTGLNQYHLAPVPVIFLASICGG
                     VLGTVVSKVLPENWVRYCFKGMLFFVMGMTLYNLFHIL"
     gene            complement(9404..10252)
                     /locus_tag="VQ543_000772"
     CDS             complement(9404..10252)
                     /locus_tag="VQ543_000772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000782422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formylglycine-generating enzyme family protein"
                     /protein_id="HET2611523.1"
                     /translation="MKMKKIKGGTFMMGTNSEEGFLDDFEGPQVAVSVKDFSIADTPV
                     TNQEFAQFVKETGYKTLAERQEWSFVFILFVPEAEREGYPHPAGAPWWLQVPNACWKH
                     PYGENSNLVGLEDHPVVHVALEDALAFCNWSGMSLPTEAQWEYAARGGRQSEYPWGDT
                     LLEGGYYHANTWQGRFPYENTALDRFIGTAPVYEFLPNDFGLYQMIGNVWEWCRNPRY
                     TLLASFNEDDYELPKYGIQDEEYAIRGGSFLCHCSYCNRYRVAARNGCISTSTSSHLG
                     FRCLKE"
     gene            complement(10249..11724)
                     /locus_tag="VQ543_000773"
     CDS             complement(10249..11724)
                     /locus_tag="VQ543_000773"
                     /EC_number="3.1.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arylsulfatase"
                     /protein_id="HET2611524.1"
                     /translation="MVQTKQPNIILIVVDQMRADALSLNSKDKLVSTPTLDMMASVGY
                     NFENAYSPVPSCVPARAALLTGLDQDKSGRVGYQDEVPWNFTNTLPKVFKDMGYQTEC
                     IGKMHVFPSRQRLGFDHVLLHDGYLHVDRKYDKAYGSQFDYVSDYLAFLKGKVGYDVD
                     LIDDGMDCNSWEARPWDKDEKLHPTNWVVSESISFLQRRDPTVPFFLKMSFEKPHAPL
                     NPPKYYFDMYMERLPQFLDLHIGNWEVLEKQIPSIYALRGKLKEDDQRRMVAAYFGLI
                     THIDHQISRFLTSLKEFRHDKDTIIWFVSDHGDQLGEHYLFRKGYPYQGSIHIPSFIY
                     DPAGLIAGNRGTIKQLVKIQDIFPSLVDLAGGTTTDELDGRSVKNLLFGQYEGWRTEF
                     HGEHALGKDSSQYILTDQWKFIWFPVLNHYQLFDMKKDPHEMNDLYPSEKYQPIVRQM
                     KKKLVDFLRYREEGFVVDEELVPVELSKITPTLTKTGDSQS"
     gene            complement(12047..13402)
                     /locus_tag="VQ543_000774"
     CDS             complement(12047..13402)
                     /locus_tag="VQ543_000774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001095003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HET2611525.1"
                     /translation="MNTMLDKMQEKLSPIAMKVGNQKFLVALRDSFVGTMPVIMTGSI
                     ALLLNAFLVDLPQQFHLESITKTFQWLVDINNLVFKGSIPIVSLLFIYCLGVNIAKIY
                     KVDTVSAGLVSLASFVISIGSTVTKSFPLANVGDVKLDQILQGIDNLAFDGKNLMVTI
                     GNVIPGNHINARGYFTAMMIGFLASIIFCKVMKKNWVIKLPDSVPPAIAKPFTSIIPG
                     FMAMYIVAILTYVFHLLSNDLLIDWVYKVLQTPLLGLSQSFFAVILMIFLNKLFWFFG
                     LHGGNVLAPIMEGLFGVAMLANLDAFQKGEPIPYIWTSGSFGAFVWFGGLGLVLAILI
                     FSRNSHYRKVAKLGLAPVLFNIGEPVNYGLPVVLNPLLFIPFVLSPVFMATVAYWATS
                     WGLVSPVTQNVTWVMPPILYGFFSTAFDWRAIILSVVCLIISVLTYFPFVKMADKTEL
                     S"
     gene            complement(13412..13729)
                     /locus_tag="VQ543_000775"
     CDS             complement(13412..13729)
                     /locus_tag="VQ543_000775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000344536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HET2611526.1"
                     /translation="MDESNLESVMGLIMYGGEAKSNAMEAIQAAKKGDFSKANRRLAD
                     ANAALLQAHKAQTEMLTREAQGEETSISLLMVHAQDHLMTSLTFVDLAKEVVEVYERF
                     EKN"
     gene            complement(13746..14063)
                     /locus_tag="VQ543_000776"
     CDS             complement(13746..14063)
                     /locus_tag="VQ543_000776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001151647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HET2611527.1"
                     /translation="MAKVTIMLACAAGMSTSLLVTKMQKAAEDKGLDAEIFAVPAPEA
                     EEIVATKEVNVLLLGPQVRYLLGDFQEKLKDRQIPVAVIPMTDYGMMNGSKVLDLAES
                     LLD"
     gene            complement(14076..15761)
                     /locus_tag="VQ543_000777"
     CDS             complement(14076..15761)
                     /locus_tag="VQ543_000777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000791288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 16 glycosylhydrolase"
                     /protein_id="HET2611528.1"
                     /translation="MKNKKLISSLFILFLLIFIHVKVFANENLIKNSNFEQGELFWNS
                     RNRGIINSNESYSNGHYSGMIPSTAINDNRADGYIGQVIDIEPNEDYLVSAFAKVDIS
                     GAEGYFTARWFDNNKQGEIVQNNIGEAVDQTVNTTEWKKYMFSFNSGKHDKVLIQLVK
                     WSEDDTTKKSNIFIDNVEMYQLSKGNSYKKIWRDDFDGEQLNKKYWGYELGSIRGWEQ
                     QHYVRSDENVFLRSGNLVLRATNRSKEDQYFNPRNNHRKVVYNSGSVRTHGKVEFLYG
                     KLEMRAKLPKGQGVFPAFWTLGSDFTLDGKINPVQGRGWPSTGEIDIMELVGERNSNG
                     SGNKTVYQTLHYGQSDNDDGKFAGRGTAFKLSSGNFNDSYHTFSIDWYKDYIVWMVDN
                     HIVRKVYYGSDNIAKKIFNRPQYVQLNLAMGGSWPGVVDNNLSGTEFVVDYVSYSRND
                     LQQHQAEEYYSQSPKINGAKDIVINRGDVPDLLKGITTNSGYELDYSIENEPMFNNFG
                     GNTSVDLLIRNKTEKEKISQMPPGVYNLHYTSRPKHLDYESKVDRKTVTLTIK"
     gene            complement(15766..16662)
                     /locus_tag="VQ543_000778"
     CDS             complement(15766..16662)
                     /locus_tag="VQ543_000778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="haloacid dehalogenase-like hydrolase"
                     /protein_id="HET2611529.1"
                     /translation="MKRLISANPSEILQMNAEELKQSILASEGRVVLSENVVTRETFV
                     GDITNSEIARAFGADMILLNCVDVFEPKIYALDSSGDDVIHRLHQLVACPIGVNLEPI
                     DPSAKMLEETQEIVAGRVASVETLNRIEELGFDFVCLTGNPGTGVSNREIIKAVQTAK
                     ENFSGLIIAGKMHGAGVNEPVAELSVAEQLLEAGADVILVPAVGTVPAFHDQELREVV
                     DLVHSKGGLVLSAIGTSQETSDTDTIKEIALRNKICGVDIQHIGDAGYGGLATVDNIY
                     ALSKAIRGVRHTVSRLARSVNR"
     gene            complement(16665..17927)
                     /locus_tag="VQ543_000779"
     CDS             complement(16665..17927)
                     /locus_tag="VQ543_000779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000413340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HET2611530.1"
                     /translation="MEKLLQEKLLPVAARLGNNKALVSIRDGITLTIPLLLIGSLLMV
                     IASFPIPGWEKYLGDIGVADYLWKGVDSSFGLLGLVASFGIAYFMARQYKVDGIPAGI
                     VSLSSFITVTPFITGEAGAGMPTAFMASKGLFVAMILGLINGYIYQWFINHNIQIKMP
                     DGVPPAVSKSFSAIIPGAVTIVGWLIVYATLDKLSLPNLHEIAQGALGGPLGLLGNNV
                     IGLLILIFLNSSFWFVGLHGGNVVNAVMKPLWLANLDANKVAYQTGETLPNIFTSVFM
                     DNFVFIGGGGATIGLVLALGYLAHKKKASKQLKTLAPITVIPGLFNINEPAMFGVPIV
                     LNILLLVPFILAPMFNLLVAWGAMASGLVPLTYTDPSWTMPPVISGLLATGSISGSLL
                     QIVLIVLDVLLYLPFVIAIEKRFKLLED"
     gene            18207..19385
                     /locus_tag="VQ543_000780"
     CDS             18207..19385
                     /locus_tag="VQ543_000780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000175872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family transcriptional regulator"
                     /protein_id="HET2611531.1"
                     /translation="MTLSKKQLQLRAKILETVYTLGPISRIEIATKTGITPATTSSIT
                     NDLIKENILLELGEDEHDTSVGRKKILLDIQAKRFYYIGCELSEKHFTFALGDNLGNI
                     LKEEKEIVTKQLIQEKGNQLINQTLKQFLNNCSDYEIEAIGIALPGRYLDDYKITTNN
                     PLWQHIDLEMIQSHFDKPLFFSNNVNCMAIGKRLFSRQQNDPNFAYFHFARGMHCSYI
                     YDGNIYGKGNLMIGEIGHTVVSSEGEECSCGRKGCLQTFAGESWLIKKSKILYHQSPY
                     SLLPSLVKNADDIDIQVILTAYQLGDTGIITLIHQALLYLSQTILNISMMIDSQKIYL
                     HSPLLTNQHIIQKLYSEMNYKPKLLYNRLPEVIIEPYNDFTAAHSAIALCLYHTILHS
                     "
     gene            complement(19613..20059)
                     /locus_tag="VQ543_000781"
     CDS             complement(19613..20059)
                     /locus_tag="VQ543_000781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000155432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET2611532.1"
                     /translation="MTIRFEEKVSIENAQFVCQWSNSLGKSFQEQWMGPRIPFLLPLQ
                     ALEGVFSIFDEQEFVGLIQKIRLEDSNLHIGRFFINPQKQEQDLGSQALRKFVSLAFE
                     NEDIDSISLNVFEANQRAQNLYQKEGFEIVQMVEAPVRKYSGLKLE"
     gene            20129..20788
                     /locus_tag="VQ543_000782"
     CDS             20129..20788
                     /locus_tag="VQ543_000782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000564993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
                     /protein_id="HET2611533.1"
                     /translation="MIDFYFFLVGSILASFLGLVIDRFPEQSIISSASHCDSCQTPLR
                     PLDLIPILSQVFNRFRCRYCKVRYPVWYALFELGLGLLFLLYSWELLSLGQVVLITAG
                     LTLGIYDFHHQEYPLLVWMTFHLILIASSGWNLVMVSFLILGILAHFIDIRMGAGDFL
                     FLASCALVFSVTELLILIQFASATGILAFLLQKKKERLPFVPFLLLATCVIIFGKLLL
                     V"
     gene            complement(20840..21991)
                     /locus_tag="VQ543_000783"
     CDS             complement(20840..21991)
                     /locus_tag="VQ543_000783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000481741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HET2611534.1"
                     /translation="MFNGRVLKELRLLNGLSRAELAQRINLTEQAIWQFESNETKPKL
                     STKMHLANQFHVDLTYFEQEEESIRFDSSVIAFRNADLATRKTIDIQTMYLHKVDSLI
                     DYFESFVIIPNITIHDLSNVVSESYHKGESIEELALYAREKLGISKDNHDLLYKLERS
                     GIYIVERLINGQADAYSAWSKLGRPYIVLGTNKSSVRRNFDLAHELGHILLHKYKDMN
                     EDGDRLEQEANYFASCFLLPKEEFLVKFEERVGKRVSNPDSYILLKSDLNVSIQALEY
                     RAFKLGLLTPKQHSYFYRQIAQKGYKMIEPLDDQIFVKKPSKVKSILDVVLSNHLVSL
                     ATIMSKQSIRLQFISEIFSVEMKFFDQYQEDRRTDRFDNIIPLYKRNNL"
     gene            complement(22006..22737)
                     /locus_tag="VQ543_000784"
     CDS             complement(22006..22737)
                     /locus_tag="VQ543_000784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000934015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2611535.1"
                     /translation="MLNQDLFDSLEAQKIVDTLMKGQKDYVDERLEKRETMIVSNGYA
                     WTRPNHIDTAFASADLFEYKLQLAGQTWGYLEFETNTEKYGKVLLIIKGKKRLTNQFP
                     LVQKNKSGYLFEYAQMNTLYLNQHSSYKNDEDSHSFPIQMELVSDEMIQEIEQATKNS
                     NIEKFMILTYEADSENNIISVDVVMPDARTGQLHLIQDLSEYIQSSSYHFEEAKYQDI
                     PNFSELSETEDFEIIPRIEKQEGQK"
     gene            22966..23067
                     /locus_tag="VQ543_000785"
                     /pseudo
     CDS             22966..23067
                     /locus_tag="VQ543_000785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000234126.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
     gene            complement(23039..23815)
                     /locus_tag="VQ543_000786"
     CDS             complement(23039..23815)
                     /locus_tag="VQ543_000786"
                     /EC_number="4.2.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan synthase subunit alpha"
                     /protein_id="HET2611536.1"
                     /translation="MPKTLTKKLNAIKAAGKGIFVPYIMAGDHEKGLDGLAETIHFLE
                     DLGVSAIEVGIPFSDPVADGPVIEEAGLRSLAHGTSTQALVETLKTIETEIPLVIMTY
                     FNPLFQYGVENFVKDLADTAVKGLIIPDLPHEHANFVEPFLADTDIALIPLVSLTTGI
                     ERQKELIEGAEGFVYAVAINGVTGKSGNYRADLDKHLAQLHQVADIPVLTGFGVSSQA
                     DLERFNAVSDGVIVGSKIVKALHQGEPIQDFIKQAVAYQK"
     gene            complement(23808..25031)
                     /gene="trpB"
                     /locus_tag="VQ543_000787"
     CDS             complement(23808..25031)
                     /gene="trpB"
                     /locus_tag="VQ543_000787"
                     /EC_number="4.2.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan synthase subunit beta"
                     /protein_id="HET2611537.1"
                     /translation="MAYQEPNKDGFYGKFGGRFVPETLMTAVLELEKAYRESQADPSF
                     QEELNQLLRQYVGRETPLYYAKNLTQHIGGAKIYLKREDLNHTGAHKINNALGQVWLA
                     KRMGKKKIIAETGAGQHGVATATAAALFNMECTIYMGEEDVKRQALNVFRMELLGAKV
                     EAVTDGSRVLKDAVNAALRSWVANIDDTHYILGSALGPHPFPEIVRDFQSVIGREAKQ
                     QYRDLTGQNLPDALVACVGGGSNAIGLFHPFVEDESVAMYGAEAAGFGVDTEHHAATL
                     TKGRPGVLHGSLMDVLQDAHGQILEAFSISAGLDYPGIGPEHSHYHDIKRASYVPVTD
                     EEALEGFQLLSRVEGIIPALESSHAIAFAVKLAKELGPEKSMIVCLSGRGDKDVVQVK
                     DRLEADAAKKGEAHA"
     gene            complement(25009..25608)
                     /locus_tag="VQ543_000788"
     CDS             complement(25009..25608)
                     /locus_tag="VQ543_000788"
                     /EC_number="5.3.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylanthranilate isomerase"
                     /protein_id="HET2611538.1"
                     /translation="MTKVKICGLSTKEAVETAVSAGADYIGFVFAPSKRQVTLEEAAE
                     LAKLIPADVKKVGVFVSPSRVELLEAIDKVGLDLVQVHGQVAADLFENLPCASIQAVQ
                     VDGNGHVPNSQADYLLFDAPVAGSGQSFDWGQLDTTGLAQPFFIAGGLNEDNVVKAIQ
                     HFTPYAVDVSSGVETDGQKDHEKIRRFIERVKHGISGTK"
     gene            complement(25595..26362)
                     /gene="trpC"
                     /locus_tag="VQ543_000789"
     CDS             complement(25595..26362)
                     /gene="trpC"
                     /locus_tag="VQ543_000789"
                     /EC_number="4.1.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011227478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="indole-3-glycerol phosphate synthase TrpC"
                     /protein_id="HET2611539.1"
                     /translation="MSQEFLARILEQKAREVEQMKLEQIQPLRQTYRLAEFLKNHQDC
                     LQVIAEVKKASPSLGDINLDVDIVQQAQTYEENGAVMISVLTDEVFFKGHLDYLREIS
                     SQVEIPTLNKDFIIDEKQIIRARNTGATVILLIVAALSEERLKELYDYATELGLEVLV
                     ETHNLAELEVAHRLGAEIIGVNNRNLTTFEVDLQTSVDLAPYFEEGRYYISESAIFTG
                     QDAERLAPYFNGILVGTALMQAENVAQRIKELQIDKG"
     gene            complement(26359..27363)
                     /gene="trpD"
                     /locus_tag="VQ543_000790"
     CDS             complement(26359..27363)
                     /gene="trpD"
                     /locus_tag="VQ543_000790"
                     /EC_number="2.4.2.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anthranilate phosphoribosyltransferase"
                     /protein_id="HET2611540.1"
                     /translation="MKEIIEKLAKFENLSGVEMTDVIERIVTGRVTEAQIASLLLALK
                     MKGETPEERTAIAQVMRGHAQHIPTEIHDAMDNCGTGGDKSFSFNISTTAAFVLAGGG
                     IHMAKHGNRSISSKSGSADVLEALGINLDLKPAELGKVFDKTGIVFLFAKNMHPAMKY
                     IMPARLELGIPTIMNLTGPLIHPMALETQLLGISRPELLESTAQVLKNMGRKRAIVVA
                     GPEGLDEAGLNGTTKIALLENGEISLSSFTPEDLGMEDYAMEDIRGGNAQENAEILLS
                     VLKNEASPFLETTVLNAGLGFYANGKIDSIKEGVALARQVIARGKALEKLRLLQEYQK
                     "
     gene            complement(27374..27940)
                     /locus_tag="VQ543_000791"
     CDS             complement(27374..27940)
                     /locus_tag="VQ543_000791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate/anthranilate synthase
                     component II"
                     /protein_id="HET2611541.1"
                     /translation="MILLIDNYDSFTYNLAQYIGNFAEVQVLRNDDSKLYEEAEKADG
                     LVFSPGPGWPVDAGKMEDMICDFAGKKPILGICLGHQAIAEVFGGKLGLAPKVMHGKQ
                     SNINFEAPSVLYQGIEDGRAVMRYHSILIEEMPEDFEVTARSTDDQAIMGIQHKNLPI
                     YGFQYHPESIGTPDGLSSIRNFIEKVVK"
     gene            complement(27937..29298)
                     /gene="trpE"
                     /locus_tag="VQ543_000792"
     CDS             complement(27937..29298)
                     /gene="trpE"
                     /locus_tag="VQ543_000792"
                     /EC_number="4.1.3.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anthranilate synthase component I"
                     /protein_id="HET2611542.1"
                     /translation="MERIIHGDVLSPILAYMRLKGQHKVILESIPRDKETARFSILAY
                     NPVFEIKFENGVLYQNGQAIDRDPLDFLYEVTHKSQHHSDLPFGGGAIGFVGYDMISL
                     YEEIGQIPEDTIGTPDMHFFVYESYMVFDHKKEKIHVIEDALYSERSQEALEKSLNQV
                     LEELRIPAPNEFEDLDLSPLDFKPHIAPHKFEGMVETARDLIRNGDMFQCVLSQRFSA
                     EVTGNPFDFYRNLRVTNPSNYLYFYDFGDYQIIGASPESLVSVKNGIVTTNPIAGTRP
                     RGATDEEDKALATDLLSDEKETAEHRMLVDLGRNDIGRISETASVQVTKYMEVELFRY
                     VMHLTSVVKGRLLAELTAMDALKATLPAGTVSGAPKIRAMRRIYELETEKRSVYAGAI
                     GYLSATGDMDLAIAIRTMILKNQRAYVQAGAGIVYDSIAQNEYQETINKAKSMTRIGE
                     LRP"
     gene            complement(29799..29876)
                     /locus_tag="VQ543_000793"
                     /pseudo
     CDS             complement(29799..29876)
                     /locus_tag="VQ543_000793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(30481..31482)
                     /locus_tag="VQ543_000794"
     CDS             complement(30481..31482)
                     /locus_tag="VQ543_000794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000789954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HET2611543.1"
                     /translation="MKNINGKKVTIYDIARLSGFSPKTVSRVINGGVNVKEETYQAIQ
                     KVIEELSYIPNAYAKNLTKKEAINILISVKKIDSFPLIWFHTLLDKVLRTCKEFGVNA
                     IVEYFGEEDTISNSIISSTGSLVDGVIVFYESVDDIRIQYLKKNHMPFLVFGESQTSG
                     VVYVSNNNFQATYDMMKAVTEEKFKNMWLLMGGESHVNKDRERGVRSFLNDKNYFMDL
                     KVIYGLSTIDSVYSYAMQHLTTQNYPDIIFVSGDEKVQGLIRACYEKGILIPDDISII
                     GFDNIPISQYYTPALSTIAPNYVKLAKEMIEGVLAIIKGESVTSVEVSPKFVRRQSF"
     gene            complement(31590..31958)
                     /locus_tag="VQ543_000795"
     CDS             complement(31590..31958)
                     /locus_tag="VQ543_000795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2611544.1"
                     /translation="MKDYKINFDLGKIEYFDNNCLIQVYKFISFYDICEMVFAFHLPP
                     DELITNVIFKEKINSMLKCYIDRLLYVFINPTHFTEKVNLQFYGSFFSYEFICREVGN
                     ILKNKGVKCNLNFFEGEEYL"
     gene            complement(32054..32764)
                     /locus_tag="VQ543_000796"
     CDS             complement(32054..32764)
                     /locus_tag="VQ543_000796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000127555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MgtC/SapB family protein"
                     /protein_id="HET2611545.1"
                     /translation="MTATSLGLSNIEIVVRIVLSVVIGSIIGLERGSKSQPAGIRTYS
                     IVCLAACLIMMTNEYVSYKFGTGDPTRLGAQVISGVGFLGAGTILITDKKKITGLTTA
                     AGIWASAGIGLAIGVGFYEGALLVAISVWGVISMFQPLKKYLQNRSKMIELYIVVKST
                     EAYNRVLVYCAENGIRMTDSRTAFGDVNSDRIEYFDVPDKKIASFITLELSGRFEHLR
                     LMEEIANIVGVIYVEEIS"
     gene            complement(32767..34458)
                     /locus_tag="VQ543_000797"
     CDS             complement(32767..34458)
                     /locus_tag="VQ543_000797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HET2611546.1"
                     /translation="MRHKLNLKDWLIRLGLIWFLVTFIIYPNFDLVVNVFVKGGEFSL
                     DAVHRVLKSQRALQSIMNSFKLAFSLIITVNVVGILCVLFTEYFDIKGAKILKLGYMT
                     SLIYGGVVLATGYKFVYGPYGLITKFLQNVIPSLDPNWFIGYGAVLFIMTFSGTANHT
                     LFLTNTIRSVDYHTIEAARNMGAKPFTVFRKVVLPTLIPTLFALTIMVFLSGLSAVAA
                     PMIVGGKEFQTINPMIITFAGMGNSRDLAALLAIILGIATTILLTIMNKIEKGGNYIS
                     ISKTKAPLKKQKIASKPWNIIAHIVAYGLFTVFMLPLIFIVLYSFTDPVAIQTGNLTL
                     SNFTLENYRLFFSNSAAFSPFLVSFIYSIIAATTATILAVVFARVVRKHKSRFDFLFE
                     YGALLPWLLPSTLLAVSLLFTFNQPQFLVLNQILVGSLVILLIAYIVVKIPFSYRMVR
                     AILFSVDDEMEDAARSMGASPFYTMMKVIIPFILPVVLSVIALNFNSLLTDFDLSVFL
                     YHPLAQPLGITIRSAGDETATSNAQALVFVYTIVLMIISGTVLYFTQRPGRKVRK"
     gene            complement(34470..35480)
                     /locus_tag="VQ543_000798"
     CDS             complement(34470..35480)
                     /locus_tag="VQ543_000798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2611547.1"
                     /translation="MIKFDNIQIKYGDFVAIDNLNLDIHEGEFFTFLGPSGCGKSTTL
                     RALVGFLDPSSGSIEVNGTDVTHLEPEKRGIGIVFQSYALFPTMTVFDNIAFGLKVKK
                     VAPDVIKAKVSAVAAKIKISDQQLQRNVSELSGGQQQRVALARALVLEPKILCLDEPL
                     SNLDAKLRVDLRKELKRLQKELGITTLYVTHDQEEALTLSDRIAVFNNGYIEQVGTPV
                     EIYHNSQTEFVCDFIGDINVLTDETVHEVLLKNTSVFLEDKKGYIRLEKVRFNRETEQ
                     DFILKGTIIDVEFSGVTIHYTIKVSESQILNVTSIDSQAAIRSVGESVELFITPSDVL
                     QF"
     gene            complement(35583..36650)
                     /locus_tag="VQ543_000799"
     CDS             complement(35583..36650)
                     /locus_tag="VQ543_000799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HET2611548.1"
                     /translation="MKKMKVWSTVLATGVALTTLAACSGGSNSTTASSSEEKADKSQE
                     LVIYSNSVSNGRGDWLTAKAKEAGFNIKMVDIAGAQLADRVIAEKNNAVADMVFGIGA
                     VDSNKIRDQKLLVQYKPKWLDKIDQSLSDKDNYYNPVIVQPLVLIGAPDVKEMPKDWT
                     ELGSKYKGKYSIYGLQGGTGRAILASILVRYLDEKGDLGVSEKGWEVAKEYFANAYTL
                     QKGESSVVKALDKESPIQYGMIWGSGALIGQKEQNVEFKVMTPEIGVPFVTEQTMVLS
                     TSKKQALAKEFIDWFGQSEIQVEYSKKFGSIPANKDALKELPEDTKKFVDQVKPQNID
                     WEAVGKHLDEWVEKAELEYVK"
     gene            complement(36675..37334)
                     /locus_tag="VQ543_000800"
     CDS             complement(36675..37334)
                     /locus_tag="VQ543_000800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000793810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1868 domain-containing protein"
                     /protein_id="HET2611549.1"
                     /translation="MKNLTKIKFKENGEFNHFPGNTVVANLYTKQDLMEVVDIIQSRY
                     RELPFIDKFTLTPRNSIHMTVIELLCHENRETEFWSSNLPLDTPLQEIHDYFAKQLEI
                     FPLLDEEIHMRITEMGKQNILVEPADEASAKRLEEIRTYVSEKAGVCFPNHDRYQFHI
                     SIGYLRIPLTEEEEEEFTKVRAELTEILLEKIPTITVNRIDYTVFEDMRQFVPYHEKF
                     K"
BASE COUNT        12046 a         7633 c         5730 g        12043 t
ORIGIN      
        1 gtacaccata gtaattgttg agtttaatgg gccaccttgc gtcataacca ttggttgtac
       61 aatcagctta aaagcagaaa ttaaagttgt taacaataca aacagggctg ttggttttag
      121 taggggcatc gtgatataac gaaactgagc ccattttgag aatccatcta attcagcagc
      181 ttcatagaca tcttgtggaa tattctgcat tcctcctaaa aataaaagca tctgataacc
      241 tgcaccctgc caagcagaaa caaaaacaat tgcatacata gcttgtttag gactagtcaa
      301 gaaaggttga gaagcaatac ctaccttatt taaaatagca tttaataagc cactatttgg
      361 atttaaaaga taaagccaaa gaatagaaat aactaccaag gacatgacaa ctggagcaaa
      421 aaaagccact ttaaaaaaca tatttccttt tcgcttttta ttgacaatca aagccattcc
      481 taaggccgct cccaattgaa ctggaataat ccaaacaaca aatttcaaag tattcaagaa
      541 gctctttaag aaaatcggat cttttgttaa tcgaataaaa ttttcaagtc caacaaattt
      601 tctttcatct ggtgtcaaca aataataatc tgtaaaagcg taataaatga ccattccaac
      661 tggaattact aaaaagatac ctaataaaat taaagctgga gctaaaaaac tataacctaa
      721 tatgttatcc tttatttttt cacgtctttt tgtatacaca acagtttctt tactcatatc
      781 catctccttt aatcatatat atcaaactag gctattaaca agaaagggga aggtagttcc
      841 aaacattttc cttccacctt cttttttaca gattatttga gtgactgatc aatagcagtt
      901 tgcatttctt ttgtacgagt atccaagact ttttgcacat ttggattttc ttcataatag
      961 ctaatatctt gcattgcttg ttgaaaagct cgagaaacct gaggatatgc tacgacaact
     1021 gggcgagcat gagctgtttt tgaattttgt tccatcaaga aacgcattgg ttcggatact
     1081 ttatctttga tattttcaat tgtagattta cgaattggaa ggaccgaatt ccccaagcta
     1141 ataatttcac ttgattctgt atttgtagca aatttaacaa attcagatgc ggcctctttt
     1201 ttatcagatt ttgtcgtcac agctaattgc caactacctg aaggggatac taattttttc
     1261 gtcttactag atactgggta aggaaggata ccaaaatcaa tatctttgta gtttgtattc
     1321 atgtcagcaa tcgtccaaga accactcaaa agcattggat actctcctgt ttcaaaacct
     1381 ttttcgactg gactaacagt tgtatagcct tcttttacaa gattttgaat gaattgaact
     1441 gcttctacac tctctttgga gttgaagtat ccttctgcct ttgttccatc ttcgtttacg
     1501 acagaaccat tatttgacca aatcaacggc atataagcat atggcaacat ttcatcgttt
     1561 gaattaatac gaaaatcaat tgctggtttg ttataatgat ctttcaattt tttagcaatc
     1621 gtattaaatt cgtcccatgt ccatggcttt tctagcgttg gaagctctga ttccgcaatt
     1681 ccagcctctt tgaacatttt tttattgtaa taaacaccaa cattcgattc agaaaatcca
     1741 aatgcataga atttcccatt ataagttccc tgttgtttaa tactgtccaa aacatcatcc
     1801 atattattat cttttagata atcatctagc ggagtaatta ctttagattt tgcataagct
     1861 gccgtatttg gtccatcaag ggtaataaca tctggaagac tattagtcgt aatagcagca
     1921 ttaaccttgt cttcatatcc tccaccacta ccactacgag gaatatactc agttacaacc
     1981 ttgtacttac tttttcctga ttgattaaag ttatcaacaa ctttttgcca agcttttcct
     2041 tcatttgttt cgtcagagaa ttgtacccag actttaatat catttgaaga actcgcttgt
     2101 tttgagttag ttcctccact acaacctgca agtatagcta acgatagccc cgcaacaaca
     2161 gataacattg tacctttacg catcattttt ctcctttttg aaacgtttca ttttttattt
     2221 attttttaaa caagcttcta gcctattttt gaaacgtttc atttgttgat tatattataa
     2281 cagcgctttc attaattgtc aagcgctttt taaatttttt ttgttgtttt atctccccca
     2341 aaatatgtgg gaattacgat tcgtttttct agaatctctt ctcgcttaat cattttcagt
     2401 atcattgcaa cagattcttt tgccatcata ccaatatctt gaactattgt agacactaga
     2461 taagattgat cgacagaagt ttttaaacca tcaaacccaa ttatctggta atcatcaggt
     2521 gctattttcc ccagttcttt cataacacta ataactctca gagccatcat atcatttatt
     2581 gtaaatatac catcaatttc tttatgagat tgcaaaaaaa ttcttatctg atcttcagga
     2641 tttattaaag gttctttcat ttcaaaatta tagacatcta ctcctaattc cttagctttt
     2701 tctctgaatc ctttacttct gagtatagtc tcattctcat acatattaat tgaaccaata
     2761 aaagcaaggt gcttattatc ccttctaacc agttcctctg ctgcagtttg tcctcctttg
     2821 taatttgctg aagtaacata gcatacattt tccgaaaaat gtctatctat acttacaaac
     2881 ggtaaatcag ataaaatata tttgtcaata tcagaatatg taataccaat aattccatcc
     2941 actttatttt gtttcaacat ttcgatatat tcgatttcat tttgtgaatc gctatcagcg
     3001 ttacaaataa ataatttata attatatttt aataactctt tctcaacatg ataggcaaac
     3061 tccgaaaaaa atggatgcca tatgctcgga ataatcaaag cgatagtttc tgttctattc
     3121 tttttcatac ctcgagcata attatcaggg atatagtcca atgtttttat agccctttga
     3181 actttcctta aagttacttc tttaatgcct ttttctttat taattacacg tgaaacagtt
     3241 ccaacactaa ctcctgcttc taaagcaaca tctttcatgg taattgattt tctttgttct
     3301 accatattat cacctccttt caatatatag tatcatgcaa atgcttttta agcaactatt
     3361 tctcaatcat ttttggccag atcatttatc ccatcatgaa taaaatcact ccaattagct
     3421 tttgaaaata cttcaatttt catgtgtaaa catctacata aaacaggaaa agccttggtt
     3481 ttatggcttt tttcgtatct tctacaaaaa aagcaagagt tttagagggc tataaatcta
     3541 gatgtacatt ttgcttaaat gattgaaggt cttttcttaa caaaaacacc ccaaaaatta
     3601 gattttttct gtctaacttt tgaggtacag ttcaaacgcg aaatagcgtt tttttgttat
     3661 ttttggttac tcatctaatc gaataaacat catggcattt aacaaatata tgagtgagac
     3721 cgtgtttata ttatttgaat agatgagtct cttattttca ataggaggaa taataaaatt
     3781 agaaataatg atatcataag atgaatcttc taaagattcc tttgataatt ctaattcagt
     3841 ccaaacttcc agttcaaaat tattgctaca gtaataagaa agtgtctctg caacgaattt
     3901 tgcatgatac tgatcaaaat tactcataac caaaaccttt agtttaggct gattttgtag
     3961 caaattaatc accaaatgtt tggtatgagt gatgaaggta taagatagat gatttaccat
     4021 cattgaacta gaacaaacct caagagtctc taaatagtga gaaagctctt tttttatatc
     4081 tgaaacaaat tttggaaaaa tattttgaaa gttcctgatt gtattccctt tttgatcaaa
     4141 taaaataaac tcagtaaaca actcttgacg atacagatgt gcggtattat gcagatgcca
     4201 aatcagatta tccttattct ccatttcaat ctgatacttg actgaaatct gatcaataaa
     4261 atcactcaat agatggtaag atttttcaac ataactatcc ttttttacgc atttcataaa
     4321 gagactttca tctatgaaaa acattttttg aaagtaagac acaaataatt ggcaaacaac
     4381 ttcttcatct aaagagatat tgtattctga ttcaaaactc tgagcaacac cttctattcc
     4441 ttctgcctgc attaaaaaat ccaaactttg gtcgttaaaa gaatctttat ctacttccat
     4501 aaaatgacca aactttattc tatataggtt cgtaactagg agcaacttta gcattctatg
     4561 cgttgacaaa ttcattggaa agcttgtttc cttataaacc aattctaaca attgagatag
     4621 tggctctgat gaaaaatttt caaatggcca ttctaggaaa taatattttt ctgaaaaata
     4681 ttgtgcaaaa aagtaacgaa tgtctctctc atttccaatg atttgaacag gggtcagact
     4741 gacttcaaat tgaaattgcc ttttaatcac tttattgatt tggctaataa tacgatagag
     4801 cgaagatgaa ctgatataaa attctttaca aatactctca gcttgacaac cttcattaaa
     4861 gaagatgaat tctaaaatcg aaaaatgagt tgaatgttta aagaaatgat ggtaaaccat
     4921 ttcaatatca ctatcatcgg tattaataat gcgtatacca ttagtagaag aatgaaaaat
     4981 caagtcagga aaagcagatt taacatggga tagatcatct ttgactgcac gttctgtaca
     5041 atttaataac tctgctagtt cagaacgatg aaaccaacgt ttatgttcaa ataataattc
     5101 taataattct aattgcctat gacttttttt agataataaa tctctcatga atatctttct
     5161 ctctttataa attatcggat taaacctctt gcaattatac cacaaagaat aggtatagca
     5221 tgatataacg acttttccta aaatctttta tttcgtataa taacactacg gagacaatat
     5281 ataaacaatt ttcttatttt accgtctatt gagggcgtga atacagaatc aaattcaagt
     5341 ctaaagatta tatttttaat tttaaaaatt atataatagc aacaattaaa gaatttgatt
     5401 ttttaaaatt atataataat aacaatcgaa ataattgact tttctatatt aaagttatat
     5461 aatagtatta atcaaagaaa ttgatttttt gatattaaaa taaaaaagga gggtaggcag
     5521 tgttgtgatc aattattgct ggaggtctta ttggtctctt ggcaggtaaa atcactaaaa
     5581 aagtagttct atgggaatca tcgcaaatgt attcgctggt ttagtcgggg catatgcagg
     5641 acaatctctt ttaggtagtt ggggtccatc aatcgctgga atggctttgc tcccatctat
     5701 tgtaggtgca gcgattgtga ttactgtagt gtcattcttt acaggtagaa agtaaacttt
     5761 tcgccagtaa agttagcaaa ctatttttaa atcaatgacg ggaaaaatag tttaaatgtt
     5821 aaatcgaaag gattgtatat gtcaaaagca aagaaaatat gtttcattat tttctgtatt
     5881 ttaatcttga caattttcct tcctgttttg atagattatc atcaagttag tgatctaggt
     5941 attcatctac ttagctggag acagaactcc gtagttgaat tctatcttgc tagatatgtc
     6001 ttttggggga cagtggttct atcaacttta gttttattat ccattttagt tgtgatgttt
     6061 tatcctaaac gttacttgga aatccaactt gaaactaaaa acgatacatt aaaattaaag
     6121 aattcggcaa tcgaaggttt tgttagaagt ttggtgagtg atcatagatt gatcaagaac
     6181 ccaactgttc atgtaaattt acgaaaaaat aaatgtttcg ttcatgtaga aggtaaaatt
     6241 cttccttcag acaacatcgc tgacagatgc caaataattc aaaatgaaat aactaatgga
     6301 ttgaagcagt tttttggtat tgagcgtcaa gtaaaacttg aagttgcagt aaaaaattac
     6361 caaccaaaac ctcaaaacaa aaagactgtt agtcgtgtga agtaaggaag taaaaaatgg
     6421 aatggcttaa acaatatcga tatccaatta tcgctggtct cataggcgta tttctggctt
     6481 gtttgattgt ctcctttggc ttcttcaaaa caatatttgt attgatttta ggagcactgg
     6541 gagttgcagc tggattatat atcgaaaaaa actatataga taaataaaaa aataaaaatt
     6601 actaatttaa ttaaaggagt ttcatatgtc aaacgaaaaa aacacaaata ctaacgtaga
     6661 aaagaaagat gctactgttg tagctcacga aatcaaaggg gaacttactt acgaagataa
     6721 agttatccaa aaaatcattg gtctttcact agaaaacgtt tcaggtcttt tgggaatcga
     6781 tggtggtttc ttctcaaatc ttaaagaaaa aatcgttaac agcgatgacg taacaagtgg
     6841 tgttaacgta gaagttggta aaacacaagt tgcagttgac ttaaacgtta ttgttgagta
     6901 ccaaaaaaat gttccagctt tatattcaga aatcagagaa atcgtatctt cagaagttgc
     6961 taaaatgact gacttggaaa ttgttgaaat caacgtaaac gttgtcgaca tcaaaactaa
     7021 agaacagcat gaagcagact cagtaagcct tcaagatcgc gtatctgacg ttgctgaatc
     7081 aacaggagaa ttcacttcag aacaattcga aaaagctaaa tctggtcttg gatctggttt
     7141 ctcaactgtt caagaaaaag ttagcgaagg tgtagaagct gttaaaggtg cagcaaatgg
     7201 tgtagtatct cacgaaaaca ctcgtgtaaa ctaagataaa ataaatataa caggagaaat
     7261 tatcatgtca gtagaagaaa aattaaatca agctaaaggt tctattaaag aaggtgttgg
     7321 gaaagccatc ggtgatgaaa aaatggaaaa agaaggagca gctgaaaaag ttgtttctaa
     7381 agtaaaagaa gttgccgaag acgctaaaga cgctgtagaa ggtgctgtag aaggtgttaa
     7441 aaacatgttg agtggcgatg ataaataagg ttaaaagtta ctttatcttt ttggtaacat
     7501 tagtcaaaag agtctgagtc aagatgattc tcagaaaaca aaaagctaga gattcccaat
     7561 tgcggaactc tagcttttta attttgcctc tttctcttat tatatttcag caggttgttg
     7621 gccatgagta tgaatcccat gtcaattctc acttgacgct tacctctcag atgacatctc
     7681 ttataaccca aacaaacctt tatctgccca aagacagatt tcatatcaat cttacgttta
     7741 gcgaaaattt gtctaccctt ggaagataaa agtgcctgat attctttagt ttttaaacac
     7801 tggtaacgtt cattcatata cagtcccttt tgaggggctg attcaggttc ataatcgcag
     7861 tcaacattga tttcaaggct gtttgctttc tatctcccct ttttcatgat atattttcgt
     7921 acaggttctt caatagtttc tatagtaaaa tgaaccaaaa atagtacacg ttgcggtata
     7981 atgttcttgt ggcatattca ttagattttc gtaaacagtt ctctcctatt tgtgagcgaa
     8041 caagtatagt caattgattg tcagtttgaa gaccaagagt cgtaaggcaa aggatatggc
     8101 agaatccatc caagggtggc tggcacaatt tctagtgaac ctctttaaat ctattacgtt
     8161 tgactgtgga aaagagtttt caaaatggaa agatatttcc aatcatcacg atagtgagag
     8221 cttttttgcg aatctaggat gttcaagaca gcggcgtctc aacgaacatt caaatagact
     8281 tttaaggtgt catgacttgc caaagcagac agatttcaac gaagtcagtc aagaatttta
     8341 ggctggacaa aaactcaatt tcaggagaaa atgaaataaa tattcccaca ataaaacgca
     8401 tagtatcaaa gtttttccaa cacctgatat tatgcatttt ttaattttaa agactttttc
     8461 ccagcctcaa gaaatcacat cccacctaaa tcctttggat accaaatacc tcatcaggta
     8521 ttttctgagt tggtaagaat gtctagctta atttgacaaa tggagggcgt taaatccagt
     8581 ttttacagga agtctattta aatattttca cactgacctt acaaaatatg aaataaatta
     8641 tataaagtca ttcccatgac aaagaataac atccctttaa aacagtatct tacccaattt
     8701 tcaggtaaga cttttgatac aaccgtcccc aatacccctc cgcatataga agcaagaaaa
     8761 ataactggaa caggtgctaa atgatactga tttaaacctg taaccacaac aattgtagcc
     8821 aaatgagaca gctgggaaaa gaaaataatt gcaagagaat acatcgttgc ttcttttatc
     8881 gaaatagaaa aaaacaccat caataaagat acattgagcg gaccaccacc aatccctaaa
     8941 aaactagaaa ttaagcccaa tagaagacca caaatcatat agaatcctat cttatcaaat
     9001 tgataagttt ttttaaaatc tgttaaaaca aatgatacaa gtagcatcac aaatagtaaa
     9061 atcatttgaa caatggatac tagccgtact gataactgag ataacaaaac ttgaaaaata
     9121 agatgaccta gaaatcctcc taaaacagaa gaaaaggata ccgtaaaaat caatctccat
     9181 tttatctctt tactttgtga aaatcttttg attgttgaaa taatcgccat tataaaaaca
     9241 gagaaactag aataaaaagc aatatcactg accgaatggt atccaaaact atccataagt
     9301 ggcttaatta taattccacc acccatgcct gatatagaac ccaatccact agctattata
     9361 atgattagaa aataaataat ctcaaccact ttttaagtcc atcctattct ttcaaacatc
     9421 taaaacctag atggctacta gtggaagtag agatacatcc atttctagca gctactcggt
     9481 atcgattaca ataagaacaa tgacataaaa aggaacctcc tctgatagca tactcctcat
     9541 cttgtatccc atattttggc aactcatagt catcttcatt aaaactagct aataaggtat
     9601 atctcggatt gcgacaccat tcccaaacat tcccaatcat ttgatataga ccaaaatcat
     9661 taggtaaaaa ttcatagaca ggagccgttc ctataaatct atctaaggca gtattttcat
     9721 aaggaaatct tccttgccaa gtattggcat gataatatcc accttctaaa agagtatctc
     9781 cccaaggata ttcagattgt cttcctcctc tagcagcata ttcccactgt gcttcagtag
     9841 gtaaagacat tccgctccaa ttacagaaag ccaatgcatc ttctaaagca acatgaacta
     9901 ctggatggtc ttctaaaccc actagattac tgttctcacc gtagggatgt ttccagcaag
     9961 cgttcggaac ttgtaaccac cacggagccc cagcaggatg aggatatccc tccctttctg
    10021 cctctggaac gaacaatata aaaacaaaag accactcttg tcgctcagct agtgttttat
    10081 agcctgtttc tttcacaaat tgagcaaatt cttgattcgt aactggagta tccgcaatgg
    10141 aaaaatcctt tacactaaca gcgacttgag gaccttcaaa atcatctaaa aagccctctt
    10201 cagaatttgt tcccatcata aatgtcccac ccttgatttt tttcattttc atgattgact
    10261 atcccccgtt ttcgttagag ttggcgttat tttagaaagt tcaacaggaa ctaactcttc
    10321 atccacaaca aaaccttctt ctctatatct aagaaagtct actaattttt tcttcatctg
    10381 acgaacaata ggttggtatt tttcgcttgg atacaaatca ttcatttcat gcggatcttt
    10441 tttcatatca aataactgat aatgatttaa aacaggaaac cagataaatt tccactggtc
    10501 tgtcaagata tattgactag aatcttttcc taaagcatgt tcaccatgaa attctgttcg
    10561 ccacccctcg tactgtccaa ataataaatt cttaacactc cgtccatcta gttcatctgt
    10621 agtagttcct cctgccaaat ccacgagtga aggaaaaata tcttgaattt tcactaattg
    10681 cttgattgtt cccctattac cagctatcaa tccagccgga tcgtaaataa acgaaggaat
    10741 gtggatactt ccctgataag gatatccctt tctaaacaga taatgttcac caagctgatc
    10801 tccatgatcc gaaacaaacc agataatcgt atctttatca tgacgaaatt cttttaggga
    10861 agtcaaaaag cgactaattt gatggtctat atgagtaatc aatccaaaat aagcagcaac
    10921 cattcttctt tgatcatctt cctttaattt ccctcttaaa gcataaatag acggaatttg
    10981 cttttctaat acttcccaat tcccgatatg caaatcgaga aattgaggca agcgttccat
    11041 atacatatca aaatagtatt ttgggggatt taatggagca tgtggttttt caaaagacat
    11101 tttgagaaaa aaaggaaccg ttggatctct tctttgtaaa aatgaaatgg actcactcac
    11161 aacccagttt gttggatgta acttctcatc tttatcccaa ggtctagctt cccaagaatt
    11221 acaatccatt ccgtcatcaa tcaaatcaac atcataacca actttaccct ttaaaaaggc
    11281 tagatagtca ctaacataat caaattgact tccataagcc ttatcatact ttctatcaac
    11341 atgtagatac ccatcgtgaa gtaagacatg atcaaaccca agtctctgtc tggaaggaaa
    11401 aacatgcatc ttaccaatac actctgtttg ataacccata tctttaaaga cttttggaag
    11461 agtattagta aaattccaag gcacctcatc ttgataacca acacgtccac ttttatcttg
    11521 gtctaagcca gtcaataaag ctgccctagc aggaacgcaa gaaggaactg gagaataggc
    11581 attttcaaaa ttataaccta cactagccat catatctaat gttggagtgc taactagctt
    11641 atccttacta ttcaaggata aggcgtctgc tctcatttga tctacaacaa tcaaaataat
    11701 atttggctgt tttgtctgaa ccataaaatc tcctttctaa tatggcaaaa gaggcacaag
    11761 aagatatcta cctttactgc acccctttct atatcaatct ctctatataa agcaataaca
    11821 ttcttgttat gttttataga acaatgaact aaaatatgac taaatcgatt aggaaattca
    11881 aatcattttc tagtactgtt ttagaagtta cagtgtacta ttccaacttc aacaaactat
    11941 aaaccttggt ctaataacaa ttttagtgga gataagaaat cctacaccta actcatctta
    12001 cacgtaatct atttctattt tatcacaaaa aacgcaagta agaccattaa ctcaattcag
    12061 ttttatctgc cattttcaca aatgggaaat aagtcaagac actaataatc aaacaaacaa
    12121 ctgataagat gatggcacgc caatcaaatg ctgtagagaa gaaaccatat aaaattggag
    12181 gcattaccca agtaacattt tgtgtaacag gtgaaacaag accccagctt gttgcccagt
    12241 aagctaccgt tgccatgaaa accgggctaa gtacaaatgg tataaatagc aaaggattca
    12301 agacaactgg taaaccataa ttgaccggct caccaatatt aaacagaact ggtgctagac
    12361 caagtttagc aacttttcga taatgactgt ttcttgaaaa aattaaaata gcaagtacca
    12421 atcctaatcc tccaaaccag acaaacgccc caaaagaccc acttgtccat atataaggaa
    12481 tcggttcacc tttttggaaa gcatccagat tcgctaacat agcaactcca aacagccctt
    12541 ccatgatggg agccaataca tttcctccat ggagaccaaa aaaccagaat aacttattta
    12601 aaaagatcat cagaataact gcaaagaaac tttgagacaa acctagtaat ggcgtttgta
    12661 acaccttgta aacccaatca atcaataagt cattgctaag taaatggaaa acataagtca
    12721 agatggctac tatatacatc gccataaatc ctggaatgat agaagtgaac ggcttagcaa
    12781 tcgcaggggg aactgaatct ggtaacttga ttacccagtt ctttttcatt actttacaga
    12841 aaataataga ggctaaaaat ccaatcatca tggctgtaaa gtagcctctg gcattaatat
    12901 ggtttcctgg aatcacattc ccaatagtta ccatcagatt tttaccatca aatgctagat
    12961 tatcaattcc ttgtaagatc tgatctaatt tcacatctcc tacatttgcc aaagggaaac
    13021 tctttgtaac tgtacttcca atcgaaatga caaacgaagc aagtgatacc aaaccagcag
    13081 aaactgtatc aaccttgtaa atcttagcga tattcactcc caagcaatag atgaacaaca
    13141 aagaaacaat tggtatactt cccttgaata ccaaattatt gatgtcaaca agccactgaa
    13201 aggttttcgt aatactttct aggtgaaatt gttgtggtaa atccactaga aaagcattta
    13261 ataacaaagc aatggaacct gtcataataa caggcatagt ccccacaaat gaatcacgta
    13321 aagcaactaa aaacttctga ttcccaactt tcattgcaat tggagaaagt ttttcttgca
    13381 ttttatccaa cattgtattc atactaaact cctaattttt ttcaaatcgt tcgtatactt
    13441 ctaccacttc tttcgccaag tcaacaaaag tcagactcgt cattaaatga tcttgcgcgt
    13501 gtaccatcaa gaggctaatt gatgtttctt ccccctgtgc ctctcttgtc aacatttctg
    13561 tttgagcctt atgcgcctgt aataaggcag cattcgcatc agctaatctt cgattggctt
    13621 tagagaaatc cccttttttt gctgcctgaa tagcctccat agcattactt ttggcttccc
    13681 caccatacat aattagcccc attacagatt ctaaattact ttcatccata acattctcct
    13741 caatcttagt ctaataaact ttcagctaaa tctaaaactt tagaaccatt catcattccg
    13801 taatctgtca tcggaataac cgccacagga atctgtctat cttttagttt ttcttgaaag
    13861 tcccctagta aatagcgaac ttgggggcct aaaagcaaca catttacttc ttttgttgct
    13921 acaatttctt ctgcttcagg agctggaact gcaaaaattt ctgcatccaa ccccttatct
    13981 tctgctgcct tttgcatctt tgtcactagc agacttgtac tcatacctgc tgcacacgct
    14041 aacataattg ttactttagc catagcttac tccttttatt ttattgtcaa tgttactgtt
    14101 tttcgatcaa ctttagactc ataatctaaa tgtttgggac gactagtata atgcaaatta
    14161 taaactcctg gaggcatttg tgaaatcttt tctttttcag ttttattgcg aattaataaa
    14221 tctaccgaag tattccctcc aaagttatta aacataggtt cattttcaat agaataatct
    14281 aactcatatc cactattagt tgtaattcct tttaataaat caggaacatc tcctctgttt
    14341 attactatat ccttagcgcc atttattttg ggagattgac tataatactc ttcagcttga
    14401 tgttgttgta aatcatttct agagtaagaa acataatcaa ctacaaattc agtccctgat
    14461 aaattattgt ccactacccc aggccaactt cctcccatcg ctaaatttaa ctgaacatac
    14521 tgaggtctat taaaaatctt tttcgctata ttatctgatc cataatatac ttttctaaca
    14581 atatgattgt caaccatcca tacaatataa tctttatacc aatcaattga aaaagtatga
    14641 tacgaatcat taaagtttcc actcgataat ttaaaggctg taccacgtcc tgcaaatttt
    14701 ccatcatcat tatccgactg tccataatga agcgtttgat aaactgtctt attcccactt
    14761 ccatttgaat ttcgttcacc aactaattcc attatatcta tctcacctgt tgacggccat
    14821 cctcgtccct gaacaggatt aatcttccca tcaagtgtaa aatccgatcc aagagtccag
    14881 aaagcaggaa aaactccttg acctttcggt aattttgcac gcatctctaa tttaccataa
    14941 agaaattcta ctttcccatg tgttctaaca cttcctgaat tatatacaac ctttctgtga
    15001 ttgtttcttg ggttaaaata ctgatcttcc ttagagcgat tcgtagctct aagaactaaa
    15061 tttcccgaac gtagaaaaac attctcatca cttcttacat aatgttgctg ttcccaacca
    15121 cgaattgatc ctaattcata tccccaatat tttttattta attgttcgcc atcaaaatca
    15181 tctctccaaa ttttcttata tgaatttcct ttagacagtt gatacatctc tacattatca
    15241 ataaaaatat tagatttttt tgtagtatcg tcttctgacc atttcactaa ttgaatcaaa
    15301 actttatcgt gtttaccgga attgaaagaa aacatgtatt ttttccattc ggttgtatta
    15361 actgtttgat caacagcttc tccaatgtta ttttgaacaa tctctccttg cttattatta
    15421 tcaaaccatc ttgcggtaaa atatccctct gctccactaa tatctacttt ggcaaaagca
    15481 gatactaaat aatcttcatt aggttctata tcaataactt gtccaatata tccatctgct
    15541 ctattatcat taattgcagt agaaggaatc atacctgagt aatgtccgtt actataactc
    15601 tcatttgaat taattattcc cctatttcta gagttccaaa acagctctcc ttgctcaaaa
    15661 tttgaatttt ttattaaatt ttcattagca aaaactttca catgaataaa tattaataaa
    15721 aataatataa ataaacttga aattaatttc ttattcttca ttttatcacc tatttactga
    15781 cctagccaag cgagatactg tatgtctcac tcctctaatt gccttgctca atgcataaat
    15841 attatcgact gttgccagtc ccccatatcc tgcgtcacct atatgttgaa tatcaactcc
    15901 acaaatttta tttctaagtg caatttcctt gatagtatct gtatcagatg tttcttggct
    15961 agtaccaata gcactcagta ctagcccacc cttactatga acgagatcaa cgacttcacg
    16021 caactcttgg tcatgaaagg ctggaacggt tccaactgct ggaacaagta tcacatccgc
    16081 acctgcttcc aacaattgct ctgcgacaga aagctctgcc acaggctcat tcactcctgc
    16141 cccgtgcatc ttacctgcaa taatcaaacc agaaaagttt tccttagcag tttgaacagc
    16201 cttaatgatt tctcgattgc taactcctgt tccaggattt ccagtcaaac agacaaagtc
    16261 aaaacctaac tcctctattc gattcaatgt ttcaacacta gcaacacgac ctgcaacaat
    16321 ttcctgtgtt tcctctagca tctttgcaga tgggtcaatc ggttccaaat ttacaccaat
    16381 tggacaagca acaagctggt gtaagcgatg aataacatca tcacctgaac tatccaaagc
    16441 ataaatttta ggctcaaaaa catcaacaca attcaataaa atcatatcag ctccaaaagc
    16501 tctagcaatt tcagaattag ttatatcccc aacaaatgtc tcacgagtaa ctacattttc
    16561 agatagaaca actctacctt cacttgctaa aatactttgt tttaattctt cagcattcat
    16621 ctgtaatatc tcagatggat ttgcactaat taaacgtttc attctcaatc ctccaataac
    16681 ttaaaccgtt tttcaatagc tattacaaat ggtaaataaa gtaagacatc caaaacaatc
    16741 aatacaattt gtaataatga accagaaata cttcctgtag caagtaaacc acttataaca
    16801 ggtggcatag tccaacttgg atctgtataa gttagcggaa ccaaacctga tgccattgct
    16861 ccccacgcta ctagtaagtt aaacattgga gctaagataa atggaactag taacaaaatg
    16921 ttcaaaacaa taggaacgcc aaacattgct ggttcattta tattaaataa tccaggtata
    16981 acagttatag gtgccaaagt ttttagttgt ttactagctt tcttcttatg tgctaaatat
    17041 cctaacgcaa gaactaaacc tatggttgca ccaccgccac ctatgaatac aaaattatcc
    17101 ataaatacgc tagtaaaaat atttggaaga gtttctccag tttgataagc tactttattt
    17161 gcatctagat tagctaacca taacggtttc ataactgcat taacaacatt tcctccgtgt
    17221 aatcctacaa accaaaaact actattaagg aaaattaaga taagaagacc aataacatta
    17281 tttcctaaaa gtccaagtgg acctcccaaa gctccttgag caatttcatg aagattaggt
    17341 aaacttaatt tatctaaagt tgcataaaca atcaaccaac caacaatagt cactgcacca
    17401 ggaataatgg cactaaagct tttagatact gctggtggaa caccatccgg catttttatc
    17461 tgtatattat gatttataaa ccattggtag atatagccat taatcaatcc taaaatcata
    17521 gcaacaaata aaccttttga tgccatgaaa gcggtaggca ttcctgctcc agcctctcct
    17581 gtaatgaaag gcgtaactgt aataaaagat gataatgaca caataccagc aggaatacca
    17641 tcaactttgt attgtctagc cataaagtaa gcgataccaa aactagctac aagaccaagt
    17701 aatccaaaac tactatcaac acccttccat aaatagtcag caacaccaat atcacctaga
    17761 tatttttccc atcctggaat aggaaaactt gcaataacca ttagtaatga acctatcaac
    17821 aataaaggta tagttagagt aataccgtct cgaatagaaa ccaacgcttt attattaccc
    17881 aatctagccg ctactggaag taacttttct tgtaataatt tttccataac cttttcctct
    17941 taaatatatt ttattatcaa aagttatcaa ttatctttat tttttgacgt caagttatta
    18001 tttgattatc ttttgttatt tatattttac aactataaga aagccttgtc aaggatttgt
    18061 gtaaatattt gattattttt tattatcaat atataataaa aagagaccag taagcaatga
    18121 aaagcttaaa aagattaaca tctacattta tccatagcaa aaaatcatag gattttaaga
    18181 atctgacaac taggaagaaa actaatatga ccttatctaa gaaacaatta caactaagag
    18241 ctaaaatact ggaaacagtt tacacattag gtcccatttc acgaattgaa atcgctacta
    18301 aaacaggaat aacacctgca acaactagca gtatcacaaa tgatctgatt aaagaaaata
    18361 ttctcttaga acttggtgaa gacgaacacg atacaagcgt agggagaaaa aaaatcctgc
    18421 tagacattca agctaaacga ttttactaca ttggttgtga actatctgaa aaacatttca
    18481 cttttgcttt aggagataat ctaggaaata tcttaaagga agagaaagaa attgttacta
    18541 aacagttaat ccaagaaaag ggaaatcaac tcattaacca gacactaaag caattcttaa
    18601 ataactgctc tgattatgaa atagaagcaa ttggaatcgc gctacctggt cgctatttag
    18661 atgattataa aataacaaca aacaatcctt tatggcaaca tatcgactta gaaatgattc
    18721 aatcccactt tgataagcct ttgtttttct ctaacaatgt taactgtatg gctataggta
    18781 aacgcctatt tagtcgccaa cagaatgacc ctaattttgc ttattttcat tttgctagag
    18841 gtatgcactg ttcttatatc tacgacggaa acatttatgg gaaaggaaat ctaatgattg
    18901 gagaaatagg gcatacagtt gtttcatctg agggagaaga atgtagctgc gggcgcaagg
    18961 gatgcttaca aacttttgct ggagaatctt ggttaatcaa aaaatcaaaa attctatatc
    19021 atcaatctcc ctattctcta cttcctagtt tagtcaaaaa tgccgatgat attgatatcc
    19081 aagttatttt aaccgcttat caattaggtg acactggaat aatcacactt atccatcaag
    19141 ccttactcta tcttagtcaa accattttaa atatcagtat gatgattgac tctcaaaaaa
    19201 tctacctaca tagtccttta ctaacaaatc aacacatcat ccaaaaacta tatagtgaaa
    19261 tgaactacaa acccaaactg ctctataatc gcctacctga agtcattatt gaaccttaca
    19321 atgattttac agccgcacac tcagctattg cactttgttt gtatcataca attctacatt
    19381 cttaattttc tattacattt aataaatagg ctaaaaagag ggagtatatc ataaaaagcg
    19441 aataaacctg ttttctgaaa atcagaattc tgttttgttc gctttcttta tatttggaat
    19501 tatactccta tctccccttt ttcataatgt atagtgaaat gaaataataa caggacgaat
    19561 cgatcgggac agtcaaatcg atttctaaca atgttttaga aatagaggtg tactattcta
    19621 gtttcaatcc actatatttt cgtacaggtg cttcaaccat ttgaacgatt tcaaatcctt
    19681 ctttttggta aagattctga gctctttgat ttgcctcgaa gacatttaga gaaatactat
    19741 ctatatcttc attttcaaag gccaaactaa caaatttcct taaagcctgg ctacctaagt
    19801 cttgctcctg tttctggggg ttgataaaaa atctcccgat atgaagattg ctgtcttcta
    19861 gcctgatttt ctggataagt cccacaaact cttgttcatc aaagattgaa aagactcctt
    19921 ccaaggcttg aaggggcagt agaaaaggaa tccttggtcc catccattgt tcttgaaagg
    19981 atttgcctag ggagttggac cactggcata caaattgagc gttttctata ctcacctttt
    20041 cttcaaaacg aattgtcatc ttttcctcac catcttatct atgtttctcc attatactat
    20101 ttctcccatt ttttacgaat agataagtat gattgatttt tatttttttc tcgtcgggag
    20161 cattctcgct tcctttcttg gtttggtcat tgaccgtttt ccagagcaat ccattatcag
    20221 ttcagccagt cactgcgatt cctgtcagac tcccttgcgt cccttagatt tgattccgat
    20281 tctctcacag gtcttcaatc gctttcgctg tcgctactgc aaagttcgct atcctgtctg
    20341 gtatgccctc tttgaactag gcttaggact cctctttctg ctttactctt gggaattgct
    20401 ttccttgggg caagtcgtcc taatcaccgc tggtttgacc ttgggtatat acgactttca
    20461 ccatcaggaa tatcccttac tggtctggat gactttccac ctaatcctaa tagcttcctc
    20521 tggctggaat ctggtcatgg tctccttcct catacttgga attttggctc attttattga
    20581 tatccgcatg ggtgcagggg atttcctctt tttagcttct tgtgctctcg tctttagcgt
    20641 aacggagtta ctgatcttga ttcagttcgc ttctgcgacg ggtatcctgg cctttctcct
    20701 gcaaaagaaa aaggaaagac ttcctttcgt gcctttcctc ttacttgcta cttgtgtgat
    20761 tatttttggt aagctactac ttgtttgata aattccaatt tctgccatat gtactccatg
    20821 aaattatttc acagttaaat tataaattat ttcttttgta caaagggatg atgttatcaa
    20881 atcgatctgt tcttctatct tcttgatact gatcaaaaaa tttcatttcg actgaaaata
    20941 tttcgcttat aaactgtaaa cgaatacttt gtttagacat tatagtcgct agactgacta
    21001 gatgattact caaaacgacg tccagaatac tctttacttt gcttggtttt ttaacaaaaa
    21061 tttgatcatc caaaggttca atcattttgt aacctttttg cgcaatttga cgataaaagt
    21121 aagaatgttg ctttggagtc aataatccta acttaaaagc tcgatactct aaagcctgta
    21181 tcgaaacatt caaatccgac ttcaataaaa tataactatc aggattgctg acacgcttgc
    21241 caaccctctc ttcaaatttg actaaaaact cttcttttgg caataaaaaa catgatgcaa
    21301 aataatttgc ttcttgctcc aaacgatcgc catcttcatt catatcttta tatttatgta
    21361 aaagaatatg tcctagctca tgagctaaat caaaatttcg acgtacagat gatttattcg
    21421 ttcccaacac aatataaggt cttcccaatt ttgaccatgc gctataagca tcagcttggc
    21481 cattaattaa tcgttccacg atatagatgc ctgaacgttc taatttataa agcaaatcat
    21541 gattatcttt tgaaatacct aatttttccc tggcataaag agccaattcc tcaatggatt
    21601 ctcccttatg ataagattca ctcactacat tacttaggtc atgaattgta atattaggta
    21661 taattacaaa actttcaaaa taatcaatca aactatctac cttatgtaaa tacatagttt
    21721 gaatatctat tgttttccgg gttgctaggt ctgcatttct aaaggcaatt acagaagaat
    21781 caaatcgaat gctctcttct tcctgttcaa aataagttaa atcaacatga aattggttgg
    21841 ccaaatgcat tttggttgat aatttaggtt tcgtttcgtt ggactcaaac tgccaaatgg
    21901 cttgttccgt taaattaatt ctctgagcta attctgctct acttaaacca tttaacagcc
    21961 gtaattcttt caatacccga ccattaaaca tttacatact ccttactact tttgaccttc
    22021 ttgtttttct attcttggaa taatttcaaa atcttctgtt tccgataatt ctgaaaaatt
    22081 aggaatatct tgatatttag cttcttcgaa atggtacgaa cttgattgaa tatactcaga
    22141 caaatcttga atcaagtgta actgaccagt tcgtgcatca ggcataacaa catctacaga
    22201 tataatattg ttttctgagt ccgcctcata agttaaaatc ataaattttt cgatattcga
    22261 atttttagta gcttgttcaa tttcttgaat catttcatca gaaactaact ccatctgaat
    22321 tggaaaggaa tgactatctt catcattttt gtaggaagaa tgttgattaa gataaagtgt
    22381 attcatctga gcatattcaa ataagtagcc actcttattt ttttgtacca aaggaaattg
    22441 gttcgtaagt cgcttcttac cctttataat taacaatact ttcccatatt tttctgtgtt
    22501 tgtttcaaat tctaaatatc cccaagtctg tcctgctaat tgtaatttat actcaaacaa
    22561 atctgctgat gcaaatgcag tatcaatatg attaggtcgc gtccatgcat aaccattcga
    22621 cactatcatt gtctctcttt tttctagacg ttcatctaca taatcttttt gccctttcat
    22681 caaagtatct acaatttttt gtgcctcaag cgaatcaaag agatcctgat tcaacataat
    22741 tcttcctcct ccaaatactt tttaatgaat tatatcattt tcttaaagaa attactacaa
    22801 taattagctt tttcttaaag ttctgtgtca gagtaattta gaaaattata tcttctatag
    22861 taaaatcaat taaaaactga acaaatttat tgggaaattc aaatcacttt ctaaaaatat
    22921 tttaggaacc gtagtgtaat attccagatt caatttacta taaaactagc ctttctcctg
    22981 caaaagaaaa aggaaagact tcctttcgtg cctttcctct tacttgctac ttgtttaatt
    23041 atttttggta agctactgct tgtttgataa agtcctgaat cggctctcct tggtggagag
    23101 cttttactat tttcgaaccg acgataacac catctgacac cgcattgaag cgttccagat
    23161 cggcttgact agatacacca aaacctgtca agactgggat gtcggccact tgatgaagtt
    23221 gcgccaagtg cttgtccaaa tctgcacggt aattgcctga tttccctgtt accccattga
    23281 tggcaacggc atagacgaat ccctccgccc cttcaatcaa ctctttctgg cgctcaattc
    23341 ctgtggtcaa gcttactaaa ggaatcaagg cgatatctgt atctgccaaa aatggttcta
    23401 caaagttggc atgttcatga ggcaggtctg ggataatcaa gcccttcaca gctgtatcag
    23461 ccagatcttt gacaaagttc tccacaccgt actgaaagag ggggttgaag taggtcatga
    23521 tgaccagtgg aatctctgtt tcaatggttt tcaaggtttc aactaaagcc tgggtagagg
    23581 tcccgtgggc taaactgcgc aagccagctt cttcgataac aggtccatct gcaacagggt
    23641 ctgaaaaggg aatacccact tcaattgcag agacacccaa atcttctaaa aagtgaattg
    23701 tttcagcaag accatccaaa cctttttcgt ggtcaccagc catgatatag ggaacaaaaa
    23761 ttccttttcc agctgcttta atagcattta atttttttgt tagtgtctta ggcatgagct
    23821 tctcccttct ttgctgcatc tgcttccaag cggtctttta cttgaaccac atccttgtcc
    23881 ccacgacctg ataggcatac aatcatagac ttttctggtc caagttcttt ggccaatttc
    23941 accgcaaagg cgatagcatg gctagattcc aaagctggga taatcccttc cacacgagac
    24001 aagagttgga atccttccaa ggcttcttcg tctgtcacag ggacatagct ggcacgttta
    24061 atatcgtggt agtgagaatg ctctggaccg ataccaggat agtccaaacc tgctgagata
    24121 gagaaggctt caagaatttg accatgggca tcttggagca catccatgag ggaaccgtga
    24181 aggacacctg gacgaccctt ggtcaaggta gctgcgtggt gctccgtatc cacaccaaat
    24241 ccagccgctt cagctccata catggctact gactcatctt ctacaaaggg atggaagaga
    24301 ccgatggcat tcgacccacc accaacacag gctactaggg catctggcag attttgtcct
    24361 gtcaagtcac ggtactgttg tttagcctct cgaccaatga cactttggaa gtcacgaaca
    24421 atttctggaa atggatgagg ccccaaggca gaaccaagga tatagtgggt atcatctata
    24481 ttagccaccc atgaacgaag ggctgcattg accgcatcct tgagcacgcg cgaaccatct
    24541 gtcacggcct cgaccttagc tcccaaaagc tccatacgga agacattgag ggcttggcgt
    24601 ttgacatctt cctcacccat gtagatggta cattccatgt taaagagggc cgcagcagtt
    24661 gcagttgcca caccgtgctg accagcacca gtttctgcga taattttctt tttacccatg
    24721 cgtttggcaa gccaaacttg tcccaaggca ttgttaatct tgtgggctcc tgtatggtta
    24781 aggtcttccc gtttgagata aatcttggct ccgccgatat gctgggtcaa gttttttgcg
    24841 taataaagag gagtttcacg tcctacgtac tggcgcaaaa gctggtttaa ttcctcttgg
    24901 aaacttgggt ctgcctgact ttcacggtag gccttctcca actccaaaac tgctgtcatc
    24961 aatgtttctg ggacaaaacg tccgccgaat tttccgtaaa atccatcttt atttggttcc
    25021 tgatatgcca tgctttaccc tctctataaa tcttctaatc ttttcatgat ctttttgtcc
    25081 atctgtctcc actccgctcg atacatctac tgcataggga gtaaaatgtt gaattgcttt
    25141 tactacatta tcttcattaa ggccacctgc gataaagaag ggctgtgcta gtccagtcgt
    25201 atccagttga ccccaatcaa aggactgacc acttcctgcc acaggggcat caaagagtag
    25261 ataatctgcc tgagaattgg ggacatgccc atttccatct acctgcacag cctgaatact
    25321 ggcacaaggc aaattctcaa ataaatcagc tgccacctga ccgtgaactt gaaccaagtc
    25381 caagccaact ttgtcaatcg cttccagcag ttctacccga cttggtgaaa caaatactcc
    25441 aacctttttc acatctgcag gaataagctt tgccaactca gctgcctctt ctaaagtcac
    25501 ctgtctttta ctaggtgcaa agacaaaacc gatatagtcg gctcctgctg aaacggctgt
    25561 ttccaccgct tctttggtcg atagtccaca aattttaacc tttgtcaatc tgcaactcct
    25621 tgattctctg ggccacattt tctgcctgca taagagctgt ccctaccaaa attccgttaa
    25681 agtatggggc tagtcgttcc gcatcctgcc ctgtgaaaat ggcagattca gaaatgtaat
    25741 agcgaccttc ctcaaagtaa ggggctaaat ctacactggt ctgcaagtcg acctcaaagg
    25801 tagtcaagtt gcggttgttg accccgataa tctcagcacc aagtctgtgg gctacctcta
    25861 gttcagctag attgtgagtc tccactaaga cttccagacc aagctctgtc gcgtagtcat
    25921 acagttcctt gaggcgttct tcggacaagg ctgccacaat aagcaagata actgtcgcac
    25981 ctgtattgcg agcgcggatg atttgctttt catctatgat aaagtctttg ttgagcgtcg
    26041 gaatctctac ctgactggaa atttcccgta gataatccaa atgcccttta aagaaaacct
    26101 catctgtcaa caccgaaatc atcactgctc cgttttcttc ataagtctgg gcctgttgca
    26161 caatatccac atcgagattg atatctccca aactagggct agctttcttg acctcagcga
    26221 ttacctgcaa gcagtcctga tgattcttca aaaattctgc caagcgatag gtctggcgca
    26281 gaggctggat ttgctccagc ttcatctgct ccacctcacg cgccttctgc tctaagattc
    26341 gtgctaaaaa ttcctgactc atttttggta ctcctgtaac agtctgagtt tttcaagggc
    26401 cttgcctcta gcaatcactt gacgggccaa ggcaactcct tccttgatgc tatcaatctt
    26461 accattagca tagaaaccaa gaccagcatt caagactgtc gtttccaaga atggacttgc
    26521 ttcgtttttc agaacgctaa gcaaaatttc tgcattttcc tgagcattcc caccacgaat
    26581 atcttccata gcatagtctt ccattcccaa atcctctgga gtaaagcttg acaagctgat
    26641 ttcgccattt tcaagaagtg caatcttggt tgttccgttc aagccagctt catccaaccc
    26701 ttctggtcca gcaaccacga tggcacgttt gcgacccata tttttcaaaa cctgagctgt
    26761 actttctagg agttctggac gactaattcc aagaagctgt gtttctaaag ccattggatg
    26821 aatcagtgga ccagtcaagt tcataatcgt tggaattccc aattccaaac gagctggcat
    26881 gatgtatttc atagctgggt gcatattttt agcgaagaga aagacgattc cagttttatc
    26941 aaagacctta cctagttcag ctggtttgag gtcaagattg attcccaagg cttcgaggac
    27001 atctgcggaa ccagatttag aagaaatcga gcggttacca tgcttggcca tgtgaatacc
    27061 gccaccagcc aagacaaagg ctgcagttgt ggaaatatta aaactgaaag acttgtcccc
    27121 acctgtacca cagttgtcca tagcatcatg aatctcagtt ggaatatgct gggcatgtcc
    27181 tctcatgact tgggcaatgg ctgtacgttc ttcaggtgtt tcccccttca tcttaagagc
    27241 taagaggaga gaagcaatct gcgcttcagt tacacgccca gttacgatac gctcaatgac
    27301 atccgtcatt tccacacctg ataaattttc aaattttgct agtttttcaa taatctcttt
    27361 catcctagtt tcctcacttt acaaccttct cgataaaatt ccgaatagaa gacaagccgt
    27421 ctggcgttcc aatgctctct ggatggtact ggaagccata aatcggtagg tttttatgtt
    27481 gaatccccat gatggcttgg tcatcagtcg aacgagctgt cacttcaaag tcttctggca
    27541 tttcctcaat caaaatactg tgataacgca tgaccgcacg tccatcctca ataccttgat
    27601 acaaaacaga tggcgcttca aagttgatat tgctctgttt cccatgcatg acttttggag
    27661 ccaaacctag cttaccacca aagacttctg caatggcttg gtgacccaaa caaatcccta
    27721 gaatcggctt cttgcctgca aaatcacaaa tcatgtcttc catctttcca gcatcaactg
    27781 gccaaccagg accaggagaa aagaccagac catctgcttt ttcagcttct tcatacagct
    27841 tggaatcatc atttctcaaa acctgaactt ctgcaaaatt cccaatgtat tgggccaagt
    27901 tataggtaaa agaatcatag ttgtcaatca ataaaatcat ggtcttagtt ctccaattct
    27961 agtcatagat tttgctttgt taatggtttc ttggtattcg ttttgggcga tagagtcgta
    28021 gacaatccct gccccagcct gcacataggc tctttgattt ttgagaatca tggttcggat
    28081 ggcaatggcc aaatccatat cacccgtcgc agacaagtag ccgattgctc ctgcatatac
    28141 gctccgtttt tccgtttcca gttcatagat gcgtctcata gctcgaattt ttggtgctcc
    28201 agaaacggtt ccagcaggaa gcgttgcttt caaggcatcc atggcagtga gttctgcaag
    28261 caaacgtccc ttgaccacac tggtcaaatg catgacgtag cggaagagct ccacctccat
    28321 atacttagta acttggacac tggccgtttc agagatgcgg ccaatatcgt tacgccccaa
    28381 gtctaccaac attcgatgtt ctgctgtttc cttctcatca gagaggaggt cagtcgccaa
    28441 ggccttgtct tcttcatccg tagcccctct tggtcgcgtc cctgcaatcg gattggttgt
    28501 cacgatgcca tttttgacag aaaccaaact ttctggacta gctccgatga tttgataatc
    28561 cccaaaatca tagaaataaa ggtaattaga tggattagtc acgcggagat ttctgtagaa
    28621 gtcaaatgga tttccagtaa cttctgctga gaaacgctgg ctgagtacac attggaacat
    28681 atctccgtta cgaatcaagt cacgagctgt ttctaccatt ccctcaaact tatgtggagc
    28741 gatatgcggt ttgaagtcaa gtggtgataa atccaagtct tcaaattcat ttggagcagg
    28801 aatgcgtaat tcctcaagca cttggttcaa ggatttttcc aaggcctctt gactgcgctc
    28861 actataaagt gcatcctcta tgacatgtat cttctccttc ttgtggtcaa agaccatata
    28921 gctctcatag acaaagaaat gcatgtctgg cgtcccaatt gtatcctcag ggatttgacc
    28981 aatttcttca taaagcgaaa tcatatcgta accaacaaaa ccaatggctc ccccaccaaa
    29041 agggaggtct gaatggtgct ggctcttatg agtcacttca taaaggaaat ccaagggatc
    29101 ccgatcaatc gcttgaccat tttgatagag aactccattt tcaaacttaa tctcaaaaac
    29161 tggattatag gctaggatag aaaaacgagc tgtttccttg tctctcggaa tactctctaa
    29221 aataacctta tgttgcccct ttaagcgcat ataagccaag attggtgata agacatctcc
    29281 atgaatgatt cgttccattg tcatttccct ttcagttcta attctagttc gtggcgactg
    29341 tatgaaaaat ccccacgcaa aataacttgc gtgaggacga aattcgcggt gccacctcaa
    29401 ttataggatt tctcctatct ctcattcctg tctcagatat ctcctgtaac aggctgtgcg
    29461 ataaagggca ctcccttgag aatgatgttt tcttctctcg tttcagatga acccaacttt
    29521 acagctttct ctgcttgttt tcagcaacca caagctctct gtgagagaaa agactgtaat
    29581 ttttccatct attatttttt agcttctagt aatctgcaat cgcagctagg tccttgcctc
    29641 cacgaccaga gacattgatg aagagatgtt catctcggta cacctttata ctcttcgaaa
    29701 atctcttcaa accgcgtcaa cgtcgccttg ccgtaggtat ggttactgac ttcgtcagtt
    29761 ctatctgcaa cctcaaaaca gtgttttgag ctgacttcgt cagttctatc cacaacctca
    29821 aaacagtgtt ttgagcaacc tgcggctagt ttcctagttt gctctttgat tttcattgag
    29881 tattactagc ttttttcgta ttagtccagc ctttttgttt acttttagta ggaggcaagg
    29941 agctgtagat agaactcaag ttcatcaaag cgacttaagg ccctaataaa agataaacca
    30001 aacgacggat agaaaaaagc ccacacacag aatatacttc cgtgtgaggg cgttggtaac
    30061 gcggtgccac ctcaattata aagggactat ccctttacat ctctgccttg tttaacaaca
    30121 agctgcactg taaggtgtgc gcaccgaatt ttcattgttt caaattcatt ttcaaaatca
    30181 gcccactttc actacttcca accacctatt cacaatcacc acaggctccc tgaagatcaa
    30241 aaatagttac ttttctgatt tgttgaactt attttaatac tttgtttttt ctttgtcaag
    30301 acttttttac gatttttttg atatcattcg aatgtgacca tatcttcctt agatcgaaca
    30361 tgaacatgtc ccacttgtta gaaattggat ccaactcaat agaaactgaa tggaggctaa
    30421 acagaactta ttttagaaca ctccatcttt tccactagga ttttcaagaa ttaaacaata
    30481 ctagaaactc tgtctcctaa caaatttagg agaaacttca acagatgtga cactttcccc
    30541 tttaataatt gctaaaacac cttctatcat ttctttagcc aatttaacat aattgggagc
    30601 aattgtagac aaagctggag tataatactg agaaatagga atattatcaa atccaatgat
    30661 agaaatatca tctggaataa gaattccttt ctcatagcac gcacgaatca agccctgaac
    30721 cttttcatct cctgaaacaa aaataatgtc cggataattt tgggtagtca agtgctgcat
    30781 tgcataagaa taaactgaat caattgtaga taagccataa atgactttta aatccataaa
    30841 gtaattttta tcattcagaa aagaacgcac acctctttca cgatccttat taacatggga
    30901 ttctcctccc ataagcaacc acatattttt aaatttttct tcagttacag ctttcatcat
    30961 atcataagta gcttgaaaat tattattaga tacatagact actccagacg tttgagattc
    31021 accgaaaaca agaaaaggca tatggttctt ctttaaatac tgaattctga tatcatctac
    31081 actttcataa aaaacaataa caccatctac taggctacct gtgcttgata taattgaatt
    31141 actaattgta tcctcctctc caaagtactc aactatagca ttaacaccaa attctttaca
    31201 cgtccgtaac actttatcta acagcgtatg aaaccaaatt aaaggaaaag agtcgatttt
    31261 ttttacagaa atcaatatat ttatagcttc ttttttagtt aaattttttg catacgcatt
    31321 tggaatatac gacaattcct ctataacttt ttgaatcgct tgataagttt cttctttaac
    31381 atttactcca ccattaataa ctcgtgaaac tgtttttgga gaaaaacctg ataaacgtgc
    31441 aatatcataa atagttacct ttttcccatt tatatttttc atttcagtcc tccattacga
    31501 acattctaat attactatac aatatttaat tttttttaac aagagaattt agtaaattat
    31561 ttaagatcca caaattcaca aaattaattt tacaaatatt cttccccttc aaaaaaattt
    31621 aaattgcatt tcacaccttt atttttaaga atgtttccaa cttcacgaca aataaattca
    31681 tatgagaaaa aactgccata aaattgtaga ttaacttttt cagtaaaatg tgtaggattt
    31741 ataaaaacat ataatagcct gtcaatgtaa cattttaaca tagagttaat tttttcttta
    31801 aagataacat ttgttatcaa ctcatcagga ggtaaatgaa aggcaaacac catttcacaa
    31861 atatcataaa aagaaataaa tttgtatact tgtatcaaac aattattatc aaaatattct
    31921 attttaccta aatcaaaatt gattttataa tctttcataa aaacctctga gcaaaaatct
    31981 actcaaaaat tagatgatta aaacatctaa aaaacaaaag gacaaaaaca tctgtccctt
    32041 tgtttactaa atttcagcta atttcttcga cataaataac acctacaata ttagcaattt
    32101 cttccatcag tcgaagatgt tcaaatctac ctgataattc cagagtaata aatgacgcta
    32161 tttttttatc tggaacatca aagtattcaa ttctgtcaga attaacatct ccaaacgctg
    32221 ttcttgaatc ggtcattctg ataccatttt ctgcacaata aaccaataca cgattatagg
    32281 cttctgtaga tttaaccact atatacaatt caatcatttt agaacgattt tgtagatatt
    32341 tttttagtgg ttggaacatg gatatcacac cccaaacaga aatggctact aaaagagctc
    32401 cctcataaaa acctactcca atagctaatc caattcctgc cgaagcccaa atgcctgctg
    32461 cagttgtcag acctgtaatt ttctttttat ctgtaataag aatcgttcca gcgcctagaa
    32521 aacccacacc tgatataact tgagctccta atcgtgtagg atctcctgtc ccaaatttat
    32581 aagatacgta ttcattcgtc atcataatca aacatgcagc tagacaaaca atactataag
    32641 ttcggatgcc tgcaggctgg gatttgctcc ctctctctaa accaattata ctaccaatga
    32701 ctactgataa aacaatcctg acaactattt caatatttga taacccaaga ctagtggctg
    32761 tcatgattat ttccttactt tacgccccgg tctttgtgtg aagtataata ccgttccaga
    32821 aataatcatc agaacaattg tataaacaaa taccagagct tgtgcattag atgttgctgt
    32881 ttcatcacct gcagatcgaa tcgtaatacc taatggttga gctaggggat ggtaaaggaa
    32941 tacagataag tcgaagtcag ttaataaaga gttaaagttt aaagcaataa cagagagaac
    33001 aaccggtaaa ataaatggaa tgataacctt catcatagta taaaaaggtg aagcacccat
    33061 acttcttgct gcatcttcca tctcatcatc aacactaaat aaaatagcac gtaccattct
    33121 ataagaaaat gggattttta caactatata tgcaataagt agaattacca aactacctac
    33181 caaaatctga ttcaagacaa gaaattgtgg ctgattaaaa gtaaataata aacttactgc
    33241 taaaagcgta cttggtaata accaaggaag tagagcacca tattcaaata agaaatcaaa
    33301 acgagattta tgttttctga caacacgagc aaatacaact gcgagaattg ttgctgttgt
    33361 cgcagcaata atagaataaa taaagctgac caagaatgga gagaatgccg cactattact
    33421 aaagaataag cgataatttt ctaaagtaaa gtttgataat gttaagttac ctgtttgaat
    33481 tgcaactgga tctgtaaatg agtataatac tataaaaatt agtggaagca tgaaaactgt
    33541 gaacaatcca tatgctacaa tgtgagcaat gatattccaa ggcttagacg caattttttg
    33601 ttttttaaga ggcgctttag tcttagagat agaaatataa tttccacctt tttctatctt
    33661 attcatgata gtaagcaaaa ttgtagttgc aatacctaaa ataattgcaa gtaaggcagc
    33721 taaatcacga gaattcccca tccctgcaaa tgtaataatc attggattta tagtttgaaa
    33781 ttctttacca ccaacaatca tgggtgctgc tactgcagat aaaccactaa gaaaaaccat
    33841 aatagtaagt gcaaatagag ttggaattaa ggttggtaac actacttttc ggaaaacagt
    33901 aaatggtttt gctcccatat ttcgagcagc ctcaatagtg tgatagtcaa cgcttcgaat
    33961 tgtatttgtt aaaaacaatg tatgattagc agttcctgaa aatgtcataa tgaataagac
    34021 tgcaccatac ccaataaacc agttagggtc taaagaaggg ataacatttt gtaaaaattt
    34081 tgtaatcaat ccatatggac catagacaaa tttatatcca gtcgctaaaa ccactcctcc
    34141 ataaattaaa gaggtcatat aacctaattt taaaatttta gcacctttaa tatcaaagta
    34201 ctctgtaaat agaacacaaa gaatacctac gacattaact gtaataatga gtgaaaatgc
    34261 taacttaaaa ctgttcataa tactctgaag tgccctctga gattttagaa cacgatgtac
    34321 agcatcaagg gaaaattctc ctccttttac aaatacattc actactagat caaagtttgg
    34381 ataaataata aatgttacta agaaccagat taaccctaaa cgaataagcc aatcttttaa
    34441 atttaattta tgacgcatac tgcacctcct taaaattgca gaacgtctga tggtgtgata
    34501 aataattcca cactttctcc gacagatcta atagcagcct gactatcaat acttgttaca
    34561 ttaagaatct gactttcaga aacttttatt gtatagtgaa ttgtaactcc agaaaactca
    34621 acatcaataa ttgtcccttt tagaatgaaa tcttgttcag tttcacgatt gaatcgaact
    34681 ttctctaatc gaatgtatcc ttttttatct tctaagaaaa cgcttgtatt tttcagtaat
    34741 acttcgtgga ctgtttcatc ggtcaaaaca ttaatatctc caataaaatc acatacaaat
    34801 tcagtttgag aattatgata aatctctact ggtgtaccga cctgttcgat gtatccattg
    34861 ttaaagactg caattctatc agataaagtc aaggcttcct cttgatcatg agtaacatat
    34921 aaagtagtaa tacctaactc tttttgaagt cttttcaact cttttctcaa atctacacgt
    34981 aattttgcgt caaggtttga caatggttca tctagacaaa gaattttagg ttcaagaacc
    35041 agagcacgag ccaatgctac cctttgttgt tgacccccag ataattctga tacattacgc
    35101 tgtaactgtt gatcagagat cttaattttt gctgccactg ctgatacttt agctttaata
    35161 acatctggag ctaccttctt aacttttaaa ccaaatgcaa tattatcaaa aacagtcata
    35221 gttggaaata gcgcataaga ttgaaataca ataccaattc cacgcttttc aggttccaaa
    35281 tgagtgacat ctgttccatt aacttcaata cttcctgatg atggatctaa aaaacctacc
    35341 aatgctctca aagtagttga tttaccacat cctgaaggcc caagaaatgt aaagaattcc
    35401 ccttcatgta tatctaaatt cagattatca attgcaacaa aatcaccata tttaatttga
    35461 atattatcaa atttaatcat ctcactaact ccctctatta ctaaaccaaa agcctctctt
    35521 tatttcttcc ttaaatttag aaataataga gagacttgga cataaaaaat aactcttatt
    35581 tcttatttta cgtattctaa ttcagctttt tctacccatt catccaaatg ctttccaaca
    35641 gcttcccagt caatattttg tggtttcact tgatcaacaa attttttcgt atcttcaggt
    35701 aactctttta gggcatcttt atttgcagga atagatccaa attttttact atattctact
    35761 tgaatttctg attgaccaaa ccaatcaata aattctttag ctaacgcttg ttttttacta
    35821 gtgcttaaaa ccatagtttg ttcagttaca aatggtacac caatctcagg agtcataact
    35881 ttgaattcaa cattttgttc tttttgtccg attaacgctc cagaacccca gatcataccg
    35941 tattgaattg ggctttcttt atctaacgct ttaacaactg agctttcacc tttttgaaga
    36001 gtataggcat ttgcaaagta ttcttttgca acttcccatc ctttttctga tacgcctaaa
    36061 tctccttttt catcaaggta acgaactaag atacttgcta gaattgcccg tcctgtacca
    36121 ccttgaagac cataaattga atatttacct ttatacttac tacctaattc agtccaatct
    36181 ttaggcattt cttttacatc aggcgcccca attaaaacta atggttgaac aatcacagga
    36241 ttataataat tatctttatc tgataaagat tgatcaattt tatctaacca tttaggcttg
    36301 tactgtacta gtaatttttg atctctaatt ttatttgagt caacagcacc aattccaaat
    36361 accatatctg caactgcatt attcttctca gcaataacac ggtctgctaa ttgagcgcca
    36421 gcaatatcaa ccatttttat attaaaacca gcttcttttg ctttagcagt taaccaatca
    36481 ccacgaccat ttgagactga gttcgaatag attactaatt cttgactttt atcagctttt
    36541 tcttcagatg aagaagcagt cgtagaattt gaacctccag agcaagcagc aagtgtagta
    36601 agagcaactc ccgttgcaag tacagtagac caaactttca tttttttcat gataagttct
    36661 ccttttttat tattttattt aaatttttcg tgatatggaa caaattgtct catatcttca
    36721 aatacagtat agtcaatacg gtttacagta atagttggaa tcttctctaa taaaatttca
    36781 gttaattctg ctctgacttt agtaaactct tcttcctcct cttcggttag aggaatccga
    36841 agatacccaa ttgaaatatg gaattgatat ctatcatgat tagggaaaca aacacctgct
    36901 ttttctgaga cataagtacg aatttcttct aatctctttg cagaagcttc atctgcaggt
    36961 tcaactagta tgttttgttt tcccatttca gttatacgca tatgaatttc ttcatccaac
    37021 aatggaaaaa tttcaagttg tttagcaaag taatcatgta tttcctgtaa aggtgtatct
    37081 agaggaagat tactgctcca aaactccgtt tcacgatttt catggcacaa caattcaatt
    37141 acagtcatgt gaatagaatt ccttggagtt aaagtaaact tatcgataaa tggtaattct
    37201 ctataacgtg attgaataat atcaacaact tccatcaaat cttgtttagt ataaagattt
    37261 gctacaactg tattcccagg gaaatgatta aattccccat tctctttgaa cttaattttt
    37321 gttaagtttt tcatataaag accttctttt ttatatttga catcggtgtc attgtgttta
    37381 cattatacaa tgaaaccgtt tcctttgtca agcgctgtca aacatttttt ttaatttatc
    37441 tttcattaaa ag
//
LOCUS       DAVBEO010000015        37225 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 009
            SAMEA1678075-rid20185393.denovo.015, whole genome shotgun sequence.
ACCESSION   DAVBEO010000015 DAVBEO010000000
VERSION     DAVBEO010000015.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678075
            Sequence Read Archive: ERR226392
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 37225)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 37225)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980207.1
            Genome Coverage       :: 150x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:50:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 72 of 147
            Pseudo Genes (incomplete)         :: 72 of 147
            Pseudo Genes (internal stop)      :: 42 of 147
            Pseudo Genes (multiple problems)  :: 32 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..37225
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678075-rid20185393.denovo.015"
                     /strain="KS 009"
                     /db_xref="taxon:1313"
     gene            175..1938
                     /gene="aspS"
                     /locus_tag="VQ543_000801"
     CDS             175..1938
                     /gene="aspS"
                     /locus_tag="VQ543_000801"
                     /EC_number="6.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000830881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--tRNA ligase"
                     /protein_id="HET2611550.1"
                     /translation="MKRSMYAGRVREEHIGQEITLKGWVGRRRDLGGLIFIDLRDREG
                     IMQLVINPEKVSAEVMATAESLRSEFVIEVTGQVAAREQANDKLPTGAVELNVTALIV
                     LNTAKTTPFEIKDGIEANDDTRLRYRYLDLRRPEMLENLKLRAKVTHSIRNYLDELEF
                     IDVETPFLSKSTPEGARDYLVPSRVNKGHFYALPQSPQITKQLLMNAGFDRYYQIVKC
                     FRDEDLRGDRQPEFTQVDLETSFLTEKEIQDITEGLIARVMKETKGIEVTLPFPRMKY
                     DDAMALYGSDKPDTRFDMLLQDLTEVVKGVDFKVFSEAPAVKAIVVKGAADNYSRKDI
                     DKMTEVAKQYGAKGLAWVKVVDGELNGPVAKFLTGIQEELTTALALEDKDLVLFVADT
                     LEVVNATLGTLRGRIAKELGLIDNDKFNFLWVVDWPMFEWSEEEGRYMSAHHPFTLPQ
                     EETAHELEGDLAKVRAIAYDIVLNGYELGGGSLRINQKDLQERMFKALGFSTEEANDQ
                     FGFLLEAMDYGFPPHGGLAIGLDRFVMLLAGEENIREVIAFPKNNKATDPMTQAPSTV
                     ALKQLEELSLQVEEDETNKTN"
     gene            1916..2857
                     /locus_tag="VQ543_000802"
     CDS             1916..2857
                     /locus_tag="VQ543_000802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000806289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HET2611551.1"
                     /translation="MKQTKRIKRWRYYLRRFAYQIKILRVLQSISREKYDEKISASLV
                     YGFLSAVAVNFFFQPGHVYSSGATGLAQIISALSNHWFGFHIPISLSFYAINFPLMVL
                     AWYQIGHKFTVFTFITVSMSSFFIQFVPVATLTEDPIINSLFGGVVMGLGIGFALRNN
                     ISSGGTDIVSLTIRKKTGKNVGSISFLVNGTIMLIAGLTFGWKYALYSMITIFVSSRV
                     TDAVFTKQKRMQAMIVTNHPEKVIEKIHKKLHRGATMIHDAEGTYNHERKAVLITVIT
                     RAEFNEFKQIMTQVDPSSFVSVSENVHILGRFVEIDN"
     gene            complement(2977..3057)
                     /locus_tag="VQ543_000803"
                     /pseudo
     CDS             complement(2977..3057)
                     /locus_tag="VQ543_000803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(3193..4179)
                     /locus_tag="VQ543_000804"
     CDS             complement(3193..4179)
                     /locus_tag="VQ543_000804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001145427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HET2611552.1"
                     /translation="MPVTIKDVAKAAGVSPSTVTRVIQNKSTISDETKKRVRKAMKEL
                     NYHPNLNARSLVSSYTQVIGLVLPDDSDAFYQNPFFPSVLRGISQVASENHYAIQIAT
                     GKDEKERLNAISQMVYGKRVDGLIFLYAQEEDPLVKLVAEEQFPFLILGKSLSPFIPL
                     VDNDNVQAGFDATEYFIKKGCKRIAFIGGSKKLFVTKDRLTGYEQALKHYKLTTDNNR
                     IYFADEFLEEKGYKFSKRLFKHDPQIDAIITTDSLLAEGVCNYIAKHQLDVPVLSFDS
                     VNPKLNLAAYVDINSLELGRVSLETILQIINDNKNNKQICYRQLIAHKIIEK"
     gene            complement(4189..4989)
                     /locus_tag="VQ543_000805"
     CDS             complement(4189..4989)
                     /locus_tag="VQ543_000805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000938258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1189 domain-containing protein"
                     /protein_id="HET2611553.1"
                     /translation="MLPYPFSYFSSIWGFRKPLSKRFELNWFQLLFTSIFLISLSMVP
                     IAIQNSSQETYPLETFIDNVYEPLTNEVVQDLSEHATIVDGTLTYTGTASQAPSVVIG
                     PSQIKELPKDLQLHFDTNELVISKESKELTRISYRAIQTESFKSKDSLTQAISKDWYQ
                     QNRIYISLFLVLGASFLFGLNFFIVSLGASLLLYITKKSRLFSFRTFKECYHFILNCL
                     GLPTLITLILGLFGQNMTTLITVQNILFVLYLVTIFYKTHFRDPNYHK"
     gene            complement(5250..6092)
                     /locus_tag="VQ543_000806"
     CDS             complement(5250..6092)
                     /locus_tag="VQ543_000806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001065636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HET2611554.1"
                     /translation="MNNSIKLKRRLTQSLTYLYLIGLSIVIIYPLLITIMSAFKAGNV
                     SAFKLDTNIDLNFDNFKGLFTETLYGTWYLNTLIIALITMAVQTSIIVLAGYAYSRYN
                     FLARKQSLVFFLIIQMVPTMAALTAFFVMALMLNALNHNWFLIFLYVGGGIPMNAWLM
                     KGYFDTVPMSLDESAKLDGAGHFRRFWQIVLPLVRPMVAVQALWAFMGPFGDYILSSF
                     LLREKEYFTVAVGLQTFVNNAKNLKIAYFSAGAILIALPICILFFFLQKNFVSGLTSG
                     GDKG"
     gene            complement(6094..7386)
                     /locus_tag="VQ543_000807"
     CDS             complement(6094..7386)
                     /locus_tag="VQ543_000807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000414940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HET2611555.1"
                     /translation="MEKQQPSKAALLSIIPGLGQIYNKQKAKGFIFLGVTIVFVLYFL
                     ALATPELSNLITLGNKPGRDNSLFMLIRGAFHLIFVIVYVLFYFSNIKDAHTIAKRIN
                     NGIPVPRTLKDMIKGIYENGFPYLLIIPSYVAMTFAIIFPVIVTLMIAFTNYDFQHLP
                     PNKLLDWVGLTNFTNIWSLSTFRSAFGSVLSWTIIWALAASTLQIVIGIFTAIIANQP
                     FIKGKRIFGVIFLLPWAVPAFITILTFSNMFNDSVGAINTQVLPILAKFLPFLDGALI
                     PWKTDPTWTKIALIMMQGWLGFPYIYVLTLGILQSIPNDLYEAAYIDGANAWQKFRNI
                     TFPMILAVAAPTLISQYTFNFNNFSIMYLFNGGGPGSVGGGAGSTDILISWIYRLTTG
                     TSPQYSMAAAVTLIISIIVISISMIAFKKLHAFDMEDV"
     gene            complement(7497..8768)
                     /locus_tag="VQ543_000808"
     CDS             complement(7497..8768)
                     /locus_tag="VQ543_000808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000095461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HET2611556.1"
                     /translation="MSSKFMKSTAVLGTATLASLLLVACGSKTADKPADSGSSEVKEL
                     TVYVDEGYKSYIEEVAKAYEKEAGVKVTLKTGDALGGLDKLSLDNQSGNVPDVMMAPY
                     DRVGSLGSDGQLSEVKLSDGAKTDDTTKSLVTAANGKVYGAPAVIESLVMYYNKDLVK
                     DAPKTFADLENLAKDSKYAFAGEDGKTTAFLADWTNFYYTYGLLAGNGAYVFGQNGKD
                     AKDIGLANDGSIVGINYAKSWYEKWPKGMQDTEGAGNLIQTQFQEGKTAAIIDGPWKA
                     QAFKDAKVNYGVATIPTLPNGKEYAAFGGGKAWVIPQAVKNLEASQKFVDFLVATEQQ
                     KVLYDKTNEIPANTEARSYAEGKNDELTTAVIKQFKNTQPLPNISQMSAVWDPAKNML
                     FDAVSGQKDAKTAANDAVTLIKETIKQKFGE"
     gene            9318..10835
                     /gene="malQ"
                     /locus_tag="VQ543_000809"
     CDS             9318..10835
                     /gene="malQ"
                     /locus_tag="VQ543_000809"
                     /EC_number="2.4.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-alpha-glucanotransferase"
                     /protein_id="HET2611557.1"
                     /translation="MKKRQSGVLMHISSLPGAYGIGSFGQSAYDFVDFLVRTKQRYWQ
                     ILPLGATSYGDSPYQSFSAFAGNTHFIDLDILVEQGLLEASDLEGVDFGSDASEVDYA
                     KIYYARRPLLEKAVKRFFEVGDVKDFEKFAQDNQSWLELFAEYMAIKEYFDNLAWTEW
                     PDADARARKASALESYREQLADKLVYHRVTQYFFFQQWLKLKAYANDNHIEIVGDMPI
                     YVAEDSSDMWANPHLFKTDVNGKATCIAGCPPDEFSVTGQLWGNPIYDWEAMDKDGYK
                     WWIERLRESFKIYDIVRIDHFRGFESYWEIPAGSDTAAPGEWVKGPGYKLFAAVKEEL
                     GELNIIAEDLGFMTDEVIELRERTGFPGMKILQFAFNPEDESIDSPHLAPANSVMYTG
                     THDNNTVLGWYRNEIDDATREYMARYTNRKEYETVVHAMLRTVFSSVSFMAIATMQDL
                     LELDEAARMNFPSTLGGNWSWRMTEDQLTPAVEEGLLDLTTIYRRINENLVDLKK"
     gene            10861..13119
                     /locus_tag="VQ543_000810"
     CDS             10861..13119
                     /locus_tag="VQ543_000810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000950172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen/starch/alpha-glucan phosphorylase"
                     /protein_id="HET2611558.1"
                     /translation="MLSLQEFVQNRYNKTIAECSNEELYLALLNYSKLASSQKPVNTG
                     KKKVYYISAEFLIGKLLSNNLINLGLYDDVKKELAAAGKDLIEVEEVELEPSLGNGGL
                     GRLAACFIDSIATLGLNGDGVGLNYHFGLFQQVLKNNQQETIPNAWLTEQNWLVRSSR
                     SYQVPFADFTLTSTLYDIDVTGYETATKNRLRLFDLDSVDSSIIKDGINFDKTDIARN
                     LTLFLYPDDSDRQGELLRIFQQYFMVSNGAQLIIDEAIEKGSNLHDLADYAVVQINDT
                     HPSMVIPELIRLLTARGIDLDEAISIVRSMTAYTNHTILAEALEKWPLEFLQEVVPHL
                     VPIIEELDRRVKAEYKDPAVQIIDESGRVHMAHMDIHYGYSVNGVAALHTEILKNSEL
                     KAFYDLYPEKFNNKTNGITFRRWLMHANPRLSHYLDEILGDGWHHEADELEKLLSYED
                     KAAVKEKLESIKAHNKRKLARHLKEHQGVEINPNSIFDIQIKRLHEYKRQQMNALYVI
                     HKYLDIKAGNIPARPITIFFGGKAAPAYTIAQDIIHLILCMSEVIANDPAVAPHLQVV
                     MVENYNVTAASFLIPACDISEQISLASKEASGTGNMKFMLNGALTLGTMDGANVEIAE
                     LVGEENIYIFGEDSETVIDLYAKAAYKSSEFYAREAIKPLVDFIVSDAVLAAGNKERL
                     ERLYNELINKDWFMTLLDLEDYIKVKEQMLADYEDRDAWLDKVIVNISKAGFFSSDRT
                     IAQYNEDIWHLN"
     gene            complement(14163..14735)
                     /locus_tag="VQ543_000811"
     CDS             complement(14163..14735)
                     /locus_tag="VQ543_000811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2611559.1"
                     /translation="MNKLMKFISVFLTSIVLIVSAIPSVSAVYASEQVSQIETNMELQ
                     PVTSLTEEQINTLANEIQSFHPDVSQQWIKEVINRQLQGDYTIPPTYSPFRAAWQGIT
                     VNQMGALLDTAIALALGGTTAGLANLIKVKGKHAAKSAIRSAISRYLGSWFVNDVALE
                     FAINLLSPGTYLAQLWDKNDAIPNNGRINF"
     gene            complement(15357..16205)
                     /locus_tag="VQ543_000812"
     CDS             complement(15357..16205)
                     /locus_tag="VQ543_000812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001095523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HET2611560.1"
                     /translation="MNTNLKPKLQRFASATAFACPICQENLTLLETNFKCCNRHSFDL
                     AKFGYVNLAPQIKQSANYDKENFQNRQQILEAGFYQAILDAVSDLLASSKTTTTILDI
                     GCGEGFYSRKLQESHSEKTFYAFDISKDSVQIAAKSEPNWAVNWFVGDLARLPIKDAN
                     MDILLDIFSPANYGEFRRVLSKDGILIKVIPTENHLKEIRQRVQDQLTNKEYSNQDIK
                     EHFQEHFTILSSQTASLTKTITAEQLQALLSMTPLLFHVDQSKIDWSQLTEITIEAEI
                     LVGKAF"
     gene            16350..16628
                     /locus_tag="VQ543_000813"
     CDS             16350..16628
                     /locus_tag="VQ543_000813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003075836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2611561.1"
                     /translation="MLKEVLTVAKVAKKSSLFLGGVAFGTLGLKILASKEAKKGYSKA
                     LAKAYKLKDELDASVSVVKQHGDDVLQDAKYLYEQEKKEEQLDSLIGE"
     gene            16630..18693
                     /locus_tag="VQ543_000814"
     CDS             16630..18693
                     /locus_tag="VQ543_000814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000008803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HET2611562.1"
                     /translation="MSFKVLHRGYQHIRLSSSFSLTLDIQDYLRSLARDEKGIESIQF
                     YMDQQHFTLRIKEGFSVLDNAEAFLKRIDKGKVSELMTLPIRREESAYSIVSGAAVKR
                     VLFRSFVPYPIRYIWTCYQALGYIREAYQTLARKELTMEVLDCSAILLSLFMNQSKTA
                     SNIMFMLDLGNHLDQWSLKKTATDLEQSLLAKESDVFLVQGDTVVSIKSSDVQIGDVL
                     ILSQGNEILFDGQVVSGLGMVNESSLTGESFPVEKRESDLVCANTVLETGELRIRVTD
                     NQMNSRILQLIELMKKSEENKKTKQRYFIKMADKVVKYNFLGAGLTYLLTGSFSKAIS
                     FLLVDFSCALKISTPVAYLTVIKEGLNREMVIKDGDVLEKYLEVDTFLFDKTGTITTS
                     YPIVEKVLPFGDYSEEDILRISACLEEHIYHPIANAIVKQAEIEGIEHEEMHGKLQYI
                     ASKGIKSHIDGQPVLIGNYVLMQDEQIHISSEQNALIEEYKSHYNLLFLAYQNELIGM
                     FCIHTPLRKEAKTALDKLKAQGKKLILATGDTLIRTEELVKDLPFDQVYTDLKPDGKF
                     ELVEKLQKAGHTILMVGDGLNDSAALTLSDIGVVMNESADISKQMSDILLLDNRLDFF
                     QELDSLSSSLQTLIKKNIQDTVVVNSSLIGFGLFNWFSPSNLSILHNLTTLRIVLRSL
                     SIKNR"
     gene            complement(18771..20027)
                     /locus_tag="VQ543_000815"
     CDS             complement(18771..20027)
                     /locus_tag="VQ543_000815"
                     /EC_number="6.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000546895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine--tRNA ligase"
                     /protein_id="HET2611563.1"
                     /translation="MHIFDELKERGLIFQTTDEEALRKALEEGQVSYYTGYDPTADSL
                     HLGHLVAILTSRRLQLAGHKPYALVGGATGLIGDPSFKDAERSLQTKDTVDGWVKSIQ
                     GQLSRFLDFENGENKAVMVNNYDWFGSISFIDFLRDIGKYFTVNYMMSKESVKKRIET
                     GISYTEFAYQIMQGYDFFVLNQDHNVTLQIGGSDQWGNMTAGTELLRRKADKTGHVIT
                     VPLITDATGKKFGKSEGNAVWLNPEKTSPYEMYQFWMNVMDADAVRFLKIFTFLSLDE
                     IEDIRKQFEAAPHERLAQKVLAREVVTLVHGEEAYKEALNITEQLFAGNIKNLSVKEL
                     KQGLRGVPNYQVQADENNNIVELLVSSGIVNSKRQAREDVQNGAIYVNGDRIQDLDYV
                     LSDADKLENELTVIRRGKKKYFVLTY"
     gene            20169..22634
                     /locus_tag="VQ543_000816"
     CDS             20169..22634
                     /locus_tag="VQ543_000816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HET2611564.1"
                     /translation="MQNQLNELKRKMLEFFQQKQKNKKSARPGKKGSSTKKSKTLDKS
                     AIFPAILLSIKALFNLLFVLGFLGGMLGVGIALGYGVALFDKVRVPQTEELVNQVKDI
                     SSISEITYSDGTVIASIESDLLRTSISSEQISENLKKAIIATEDEHFKEHKGVVPKAV
                     IRATLGKFVGLGSSSGGSTLTQQLIKQQVVGDAPTLARKAAEIVDALALERAMNKDEI
                     LTTYLNVAPFGRNNKGQNIAGARQAAEGIFGVDASQLTVPQAAFLAGLPQSPITYSPY
                     ENTGELKSDEDLEIGLRRAKAVLYSMYRTGALSKDEYSQYKDYDLKQDFLPSGTVTGI
                     SRDYLYFTTLAEAQERMYDYLAQRDNVSAKELKNEATQKFYRDLAAKEIENGGYKITT
                     TIDQKIHSAMQSAVADYGYLLDDGTGRVEVGNVLMDNQTGAILGFVGGRNYQENQNNH
                     AFDTKRSPASTTKPLLAYGIAIDQGLMGSETILSNYPTNFANGNPIMYANSKGTGMMT
                     LGEALNYSWNIPAYWTYRMLREKGVDVKGYMEKMGYEIPEYGIESLPMGGGIEVTVAQ
                     HTNGYQTLANNGVYHQKHVISKIEAADGRVVYEYQDKPVQVYSKATATIMQGLLREVL
                     SSRVTTTFKSNLTSLNPTLANADWIGKTGTTNQDENMWLMLSTPRLTLGGWIGHDDNH
                     SLSRRAGYSNNSNYMAHLVNAIQQASPSIWGNERFALDPSVVKSEVLKSTGQKPGKVS
                     VEGKEVEVTGSTVTSYWANKSGAPATSYRFAIGGSDADYQNAWSSIVGSLPTPSSSSS
                     SSSSSSDSSNSSTTRPSSSRARR"
     gene            22699..23610
                     /locus_tag="VQ543_000817"
     CDS             22699..23610
                     /locus_tag="VQ543_000817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HET2611565.1"
                     /translation="MNQYQKKIVNGKIYSLLSGLIWGICGILGEYFFTHYQVSSGWIT
                     SMRLTLAGSLVLIWSAIQLKSQVLDIWRDKKNYLPFLAYAILGIFSVQYFFYLCLEYS
                     NATTATILQFISPVFILFYNRLVYQKRASKSAVFYVLVAMLGVCLMATKGDLSQLSMT
                     PLALITGLLSAMGVMFNVILPQPFAKRYGFVPTVGWGMILAGLFSNVLSPVYQLSFTL
                     DIWSILICLIIAFFGTAFAFFISMKAVSLVSPLVVSVISASEPLSSALLSVLFLGLVV
                     DWSLLLAIALIILPMIFLSIEEAKESR"
     gene            23840..24538
                     /gene="dapD"
                     /locus_tag="VQ543_000818"
     CDS             23840..24538
                     /gene="dapD"
                     /locus_tag="VQ543_000818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3,4,5-tetrahydropyridine-2,6-dicarboxylate
                     N-acetyltransferase"
                     /protein_id="HET2611566.1"
                     /translation="MTATKMNAQEIIQFIANAEKKTSVKVTFEGQLATAVPSSVVKLG
                     NVLFGDWKDVAPLLEGLVENQDYVVEQDARNSAVPLLDKRAINARIEPGAIIRDQVEI
                     GDNAVIMMGAVINIGAEIGAGTMIDMGAILGGRAIVGKNSHVGAGAVLAGVIEPASAE
                     PVCVGDNVLIGANAVVIEGVQIGSGSVVAAGAIVTQDVPENVVVAGVPARIIKEIDAQ
                     TQQKTALEDALRTL"
     gene            24606..25736
                     /locus_tag="VQ543_000819"
     CDS             24606..25736
                     /locus_tag="VQ543_000819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyldiaminopimelate deacetylase"
                     /protein_id="HET2611567.1"
                     /translation="MLDLIQTRRALHQIPEIGLEEFKTQAYLLDVIEKLTTGKDFVQI
                     RTWRTGILVYLQGSQPERTIGWRTDIDGLPIVEQTGLPFTSQHQGRMHACGHDFHMTI
                     ALGCLERALEEQPKNNLLFLFQPAEENEAGGMLMYEDGAFGDWLPNQFYGLHVRPDLK
                     VGQIATNTHTLFAGTCEVKIRFKGKGGHAAFPHEANDALVAASYFVTQVQSVVSRNVN
                     PIEGAVVTFGVFQAGTTNNVITDTAFLHGTIRALTQDMSLLVQKRVKTVAEGVAAAFD
                     MEVEVELKQGGYLPVENNPALARELMDFFDEKDGIELIDIEPAMTGEDFGYLLSKVDG
                     VMFWLGIDSPYALHHPQMSPKEEVLAIGVAAVSSFLKKKAAE"
     gene            25748..26287
                     /locus_tag="VQ543_000820"
     CDS             25748..26287
                     /locus_tag="VQ543_000820"
                     /EC_number="6.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-formyltetrahydrofolate cyclo-ligase"
                     /protein_id="HET2611568.1"
                     /translation="MKSELRKQVLHEMKAISQEQKQAIDQALTERILQHPFYQEAKVI
                     ATYLSFSHEFQTRELIEQALKDGKKVLTPKTYPKGRMDFVVYDPQQLVKTSFALLEPQ
                     GDLEVVDASQIDLIHVPGLAFTTDGYRIGYGGGYYDRYLEHFSGRALSTIYPCQIQDF
                     IPENHDIPVQEVLIDEGNL"
     gene            26271..26948
                     /locus_tag="VQ543_000821"
     CDS             26271..26948
                     /locus_tag="VQ543_000821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhomboid family intramembrane serine protease"
                     /protein_id="HET2611569.1"
                     /translation="MKEIFDRRYPVTSFFLLVTALVFLLMLVTAGGNFDRADTLFRFG
                     AMYGPAIRLFPEQVWRLLSAIFVHIGWEHFIVNMLSLYYLGRQVEEIFGSKQFFFLYL
                     LSGMMGNLFVFVFSPKSLAAGASTSLYGLFAAIIVLRYATRNPYIQQLGQSYLTLFVV
                     NIIGSVLIPGISLAGHIGGAVGGAFLAVIFPVRGEKRMYNTSQRLGAVVLFVGLAILL
                     FYKGMGM"
     gene            complement(27020..27919)
                     /gene="galU"
                     /locus_tag="VQ543_000822"
     CDS             complement(27020..27919)
                     /gene="galU"
                     /locus_tag="VQ543_000822"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000202216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HET2611570.1"
                     /translation="MTSKVRKAVIPAAGLGTRFLPATKALAKEMLPIVDKPTIQFIVE
                     EALKSGIEDILVVTGKSKRSIEDHFDSNFELEYNLKEKGKTDLLKLVDKTTDMRLHFI
                     RQTHPRGLGDAVLQAKAFVGNEPFVVMLGDDLMDITDEKAVPLTKQLMDDYERTHAST
                     IAVMPVPHDEVSAYGVIAPQGEGKDGLYSVETFVEKPAPEDAPSDLAIIGRYLLTPEI
                     FQILENQAPGAGNEIQLTDAIDTLNKTQRVFAREFNGARYDVGDKFGFMKTSIDYALK
                     HPQVKDDLKNYLIQLGKELTEKE"
     gene            complement(27941..28957)
                     /locus_tag="VQ543_000823"
     CDS             complement(27941..28957)
                     /locus_tag="VQ543_000823"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000415108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HET2611571.1"
                     /translation="MEKQTVAVLGPGSWGTALSQVLNDNGHEVRIWGNLPEQINEINT
                     YHTNKHYFKDVVLDENIIAYTDLAETLKDVDAILFVVPTKVTRLVAQQVAQTLDHKAI
                     IMHASKGLEPDSHKRLSTILEEEIPEQLRSDIVVVSGPSHAEETIVRDLTLITAASKD
                     LQTAQYVQELFSNHYFRLYTNTDVIGVETAGALKNIIAVGAGALHGLGFGDNAKAAII
                     ARGLAEITRLGVALGASPLTYSGLSGVGDLIVTGTSIHSRNWRAGDALGRGESLADIE
                     ANMGMVIEGISTTRAAYELAQELGVYMPITQAIYQVIYHGTNIKDAIYDIMNNEFKAE
                     NEWS"
     gene            29169..29546
                     /locus_tag="VQ543_000824"
                     /pseudo
     CDS             29169..29546
                     /locus_tag="VQ543_000824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809823.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            complement(29726..30151)
                     /locus_tag="VQ543_000825"
     CDS             complement(29726..30151)
                     /locus_tag="VQ543_000825"
                     /inference="COORDINATES: protein motif:HMM:NF025080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET2611572.1"
                     /translation="MNNLSSVDSEELFQFYRERGNAENFIKERKAGFFGDKTDSSTMI
                     KNEVRMMMGCLAYNLYLFLKQLAGDEVKSLTIKRFRRLFLHIAGKYVSTARRHILKFS
                     SLYAYSKQFQALFDTICQINLILPVPYRARGQGKTCLTE"
     gene            complement(30219..30869)
                     /gene="phoU"
                     /locus_tag="VQ543_000826"
     CDS             complement(30219..30869)
                     /gene="phoU"
                     /locus_tag="VQ543_000826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001245788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HET2611573.1"
                     /translation="MRNQFDLELHELEQSFLGLGQLVLETASKALLALASKDKEMAEL
                     IINKDHAINQGQSAIELTCARLLALQQPQVSDLRFVISIMSSCSDLERMGDHMAGIAK
                     AVLQLKENQLAPDEEQLHQMGKLSLSMLADLLVAFPLHQASKAISIAQKDEQIDQYYY
                     ALSKEIIGLMKDQETSIPNGTQYLYIIGHLERFADYIANICERLVYLETGELVDLN"
     gene            complement(30884..31636)
                     /gene="pstB"
                     /locus_tag="VQ543_000827"
     CDS             complement(30884..31636)
                     /gene="pstB"
                     /locus_tag="VQ543_000827"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003101281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HET2611574.1"
                     /translation="MGTFSVRHLDLFYGDFQALKNISIQLPERQITALIGPSGCGKST
                     FLKTLNRMNDLVPSCHIEGQVLLDEQDIYSSKFNLNQLRKRVGMVFQQPNPFAMSIYD
                     NVAYGPRTHGIRDKKQLDALVEKSLKGAAIWEEVKDDLKKSAMSLSGGQQQRLCIARA
                     LAVEPDVLLMDEPTSALDPISTLKIEDLIQQLKKDYTIIIVTHNMQQASRISDKTAFF
                     LTGEICEFGDTVDVFTNPKDQRTEDYISGRFG"
     gene            complement(31638..32453)
                     /gene="pstA"
                     /locus_tag="VQ543_000828"
     CDS             complement(31638..32453)
                     /gene="pstA"
                     /locus_tag="VQ543_000828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HET2611575.1"
                     /translation="MSKYLLKLLVYCFSALTFGSLFLIIGFILIKGLPHLSLSLFSWT
                     YTSENISLMPAIISTVILVFGALLLALPIGIFAGFYLVEYTKKDSLCVKIMRLASDTL
                     SGIPSIVFGLFGMLFFVVFLGFQYSLLSGILTSVIMVLPVIIRSTEEALLSVSDSMRQ
                     ASYGLGAGKLRTVFRIVLPVAMPGILAGVILAIGRIVGETAALMYTLGTSTNTPSSLM
                     SSGRSLALHMYMLSSEGLHVNEAYATGVILIITVLMINTLSSLLSRKLVKGAS"
     gene            complement(32446..33309)
                     /gene="pstC"
                     /locus_tag="VQ543_000829"
     CDS             complement(32446..33309)
                     /gene="pstC"
                     /locus_tag="VQ543_000829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000595184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HET2611576.1"
                     /translation="MTKQAFKEAVFRAIFFMSATVAVVAILLICFFIFSNGLPFMANY
                     GFARFLLGSDWSPTNIPASYGILPMIVGSLLITLGAIVIGVPTGILTSVFMVYYCPKP
                     VYGFLKSAINLMAAIPSIVYGFFGLQLLVPWIRTFLGNGMSVLTASLLLGIMILPTII
                     SLSESAIRTVPKTYYSGSLALGASHERSIFSVILPAARSGILSAVILGIGRAVGETMA
                     VILVAGNQPIIPSGLFSGTRTLTTNIVLEMAYASGQHREALIATSAVLFFLILLINAY
                     FAYLKGKSSYE"
     gene            complement(33427..34302)
                     /locus_tag="VQ543_000830"
     CDS             complement(33427..34302)
                     /locus_tag="VQ543_000830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate-binding protein"
                     /protein_id="HET2611577.1"
                     /translation="MKFKKMLTLAAIGLSGFGLVACGNQSAASKQSASGTIEVISREN
                     GSGTRGAFTEITGILKKDGDKKIDNTAKTAVIQNSTEGVLSAVQGNANAIGYISLGSL
                     TKSVKALEIDGVKASRDTVLDGEYPLQRPFNIVWSSNLSKLGQDFISFIHSKQGQQVV
                     TDNKFIEAKTETTEYTSQHLSGKLSVVGSTSVSSLMEKLAEAYKKENPEVTIDITSNG
                     SSAGITAVKEKTADIGMVSRELTPEEGKSLTHDAIALDGIAVVVNNDNKASQVSMAEL
                     ADVFSGKLTTWDKIK"
     gene            complement(34469..35800)
                     /locus_tag="VQ543_000831"
     CDS             complement(34469..35800)
                     /locus_tag="VQ543_000831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000833277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component sensor histidine kinase"
                     /protein_id="HET2611578.1"
                     /translation="MKRYLQFWLVNLSVSLILIAGMALTWISKGIGLFLLALSLGQGG
                     YWLFCLWKWEVAFETLHQPLLTSSEYFLEKGQEDLKSLAQYVSALKTKVSQQDQQYKD
                     LAETMEVLLSHLTMGTFLVSAQGQMLLSSRSLPHYFPDVDGDISSLDDLKRMDIRNLV
                     HQAFDQKTRLKQEVSGFHEGDLILEVTAVPVFSPTQSVEAVLVLLYDLTTIRTYEKLN
                     LAFVSNASHELRTPVTSIKGFAETIKGMSAEEEALKDDFLDIIYKESLRLEHIVEHLL
                     TLSKAQQMPIQWTTLSLAEFVQDLTQSLQPQLKKKDLQLKVQVPDDVTLVSDSQLLSQ
                     ILLNLLSNAIRYTEQGGKIEVKTQKVNEGIKISVSDTGIGISQLEQDRIFERFYRVNK
                     GRSRQTGGTGLGLAIVKELSQLLGGQVTVTSQLGRGSCFTIFLPNQSFAQD"
     gene            complement(35801..36508)
                     /locus_tag="VQ543_000832"
     CDS             complement(35801..36508)
                     /locus_tag="VQ543_000832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET2611579.1"
                     /translation="MTKQVLLVDDEEHILKLLDYHLSKEGFSTQLVTNGRKALALAET
                     EPFDFILLDIMLPQLDGMEVCKRLRAKGVKTPIMMVSAKSDEFDKVLALELGADDYLT
                     KPFSPRELLARVKAVLRRTKGEQEGDDSDNIADDSWLFGTLKVYPERHEVYKANKLLS
                     LTPKEFELLLYLMKHPNMTLTRERLLERIWGYDFGQETRLVDVHIGKLREKIEDNPKA
                     PQFIRTIRGYGYKFKEL"
     gene            complement(36592..37077)
                     /locus_tag="VQ543_000833"
     CDS             complement(36592..37077)
                     /locus_tag="VQ543_000833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HET2611580.1"
                     /translation="MAPTDKEDLIRTLELAPHVEGGYFRQTKKASDTINLAGKGRALY
                     TSIYFLLEETNPSHFHRLTADEIWYFHAGSPLTVHMITADGHYEAVTLGLDISKGQQL
                     HYCVPKGTIWGSTVDKDYALVSCLVAPGFEFEDFELFERVDLLATYPEHKEMIERLTR
                     Y"
     gene            37063..37225
                     /locus_tag="VQ543_000834"
                     /pseudo
     CDS             37063..37225
                     /locus_tag="VQ543_000834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
BASE COUNT        10913 a         7062 c         8024 g        11226 t
ORIGIN      
        1 atacctacgg taaggcgacg ctgacgtggt ttgaagagat tttcgaagag tattagcgct
       61 aatttttagg gctttcacct gacttttaaa gactggcaaa cttttctgat gattttcatg
      121 aagagcctgc gcttttatgg taaaatagta acagaataaa agaggagaga aataatgaaa
      181 cgtagtatgt atgctggtcg tgttcgtgag gaacacatcg gacaagaaat aaccttgaaa
      241 ggatgggttg gccgtcgtcg tgaccttggt ggtttgatct ttatcgatct tcgtgaccgt
      301 gaaggaatca tgcagttggt tatcaaccct gaaaaagtat ctgcagaggt tatggcaaca
      361 gctgaaagcc ttcgtagcga atttgttatt gaggtgactg gtcaggtcgc tgcgcgtgag
      421 caagccaatg ataagttgcc aactggtgcg gttgagttaa acgtgacagc tcttattgtg
      481 cttaacacag ctaagacaac accatttgag attaaggatg gcattgaggc aaatgacgat
      541 acacgtttgc gttaccgtta ccttgacctt cgtcgtccag aaatgttgga aaatcttaaa
      601 cttcgtgcca aggtgaccca ctctatccgc aactatttgg atgagttgga gtttatcgac
      661 gtggagacac cattcctttc taagtcaacg cctgaagggg cgcgtgatta tttagtgccg
      721 tctcgtgtta ataaggggca tttttacgct cttcctcaaa gtccacaaat cacgaaacag
      781 ctcttgatga atgctggttt tgaccgttac taccaaatcg ttaaatgttt ccgtgacgag
      841 gacttgcgtg gagaccgcca gcctgaattt actcaggtcg acttggaaac gtccttcctt
      901 actgagaaag aaatccaaga tattacagaa ggcttgatcg cgcgcgtgat gaaggaaaca
      961 aaaggcatcg aagtaacgct accgttccct cgtatgaaat acgatgatgc tatggctctt
     1021 tacggttctg acaagccaga tactcgtttt gacatgttgc ttcaggactt gacagaagtg
     1081 gtcaaaggtg tagactttaa agtcttttca gaagcacctg ctgtaaaagc gattgtggtc
     1141 aaaggagctg cggacaacta ttcacgtaaa gacatcgaca agatgacgga agtagccaaa
     1201 cagtatggtg ccaaaggtct tgcttgggtc aaggtggttg atggagaatt aaacggacca
     1261 gttgccaagt tcttgactgg tatccaagaa gaattgacaa cagcgcttgc tcttgaagat
     1321 aaggacttgg ttctctttgt ggcggatacg cttgaagtgg ttaatgcaac actgggtacc
     1381 cttcgtggac gtattgctaa agagcttggc ttgattgata atgataagtt caacttcctt
     1441 tgggtggttg actggccgat gtttgaatgg tctgaagaag aaggccgcta catgagcgcc
     1501 caccatccat tcacacttcc acaggaagag actgctcacg aattagaagg tgatttggct
     1561 aaggttcgtg ccattgctta cgatatcgtc ttgaacggtt atgagcttgg tggtggtagc
     1621 cttcgtatca accaaaaaga ccttcaagaa cgcatgttca aggctcttgg tttctcaact
     1681 gaagaagcca atgaccagtt tggtttcctt cttgaagcca tggactatgg tttcccaccg
     1741 cacggtggtt tggctatcgg gcttgaccgt tttgtcatgt tgcttgctgg agaagaaaat
     1801 atccgtgaag tcattgcctt tcctaagaac aacaaggcaa ctgacccaat gacacaagct
     1861 ccatcaacag tcgctctcaa acaactagag gaactcagct tacaagtaga agaagatgaa
     1921 acaaacaaaa cgaattaagc ggtggcgcta ttatctgcgc cgctttgctt atcagataaa
     1981 aattttacgt gtcttacaaa gtatctctcg agaaaagtat gatgagaaga tttcggcctc
     2041 tctggtctat ggttttttat cagcagtagc agttaatttc tttttccaac cagggcatgt
     2101 gtattcgagt ggtgcaacag gtctggcaca gattatctct gccttgagta atcactggtt
     2161 tggttttcat attccgattt cgctaagctt ctacgccatt aacttccctt tgatggtctt
     2221 agcttggtat cagattggcc ataagttcac cgtctttacc tttatcacgg tatctatgag
     2281 ttccttcttt atccagtttg tccctgtggc aaccttgacg gaggatccca ttatcaattc
     2341 cctttttggg ggtgttgtta tgggtttggg gattggtttt gctcttcgaa acaatatctc
     2401 cagtggtggg acggatatcg tcagcctgac tattcgtaag aaaacgggta agaatgtcgg
     2461 tagtatttct ttcttggtaa atggaactat catgctgata gcaggtttga cctttggttg
     2521 gaaatacgct ctttattcta tgattaccat ctttgtctct agccgtgtga cagacgcagt
     2581 ctttactaag caaaagcgta tgcaggccat gattgtgaca aatcatccag agaaggtaat
     2641 tgaaaaaatc cataaaaaat tgcaccgcgg agcaaccatg atccacgatg cagaaggaac
     2701 ctataatcac gagagaaagg cagttttaat cactgtcatt acacgtgcag agtttaatga
     2761 atttaaacag attatgacac aagtggatcc aagctccttt gtctctgtct cggaaaatgt
     2821 tcatattcta ggaagatttg ttgagataga taattagtga ttaatactct tcgaaaatct
     2881 cttcaaacca cgtcagcttc accttgccgt atatatgtta ctgacttcgt cagttctatc
     2941 tgcaacctca aaaccatgtt ttgagctgac ttcgtcagtt tcatctacaa cctcaaaacc
     3001 atgttttgag caacctgcgg ctagcttcct agtttgcact ttgattttca ttgagtataa
     3061 aaagatcttg ggaaaagact caatttcagt agaaaaggaa gtaaatcttc ccacattaaa
     3121 acgcatagta tcaagttttt tcaatacctg atagtatgcg tttttgcttt taacgacttt
     3181 ttgcccagtc tcttattttt cgataatttt gtgggcgatc aattgacggt aacaaatttg
     3241 tttattgttt ttattatcat taataatctg gagaatagtt tcaagggaaa cacgaccaag
     3301 ctctaaacta ttgatatcga cataggctgc caagttgagc ttgggattaa ccgagtcaaa
     3361 gctgagaaca gggacatcca gctggtgttt ggcaatatag ttacaaacgc cttcagctag
     3421 gaggctatcg gttgtgatga tagcatcaat ttgtggatcg tgcttgaata atcgcttgct
     3481 aaatttatag cccttttctt ccagaaactc gtcggcaaag tagatgcgat tgttgtcagt
     3541 ggtaagtttg taatgtttaa gcgcctgttc atagcctgtt aaacggtctt tggtcacgaa
     3601 gagcttttta cttcctccga taaaggcaat gcgtttgcag ccttttttga tgaaatattc
     3661 agtcgcatca aaaccagctt gaacattgtc gttgtcgaca agtgggatga aaggagatag
     3721 agatttacct aagataagga aggggaactg ttcttctgcg acgagtttta cgagagggtc
     3781 ttcttcttgg gcatagagaa agattagccc atctacacgc ttgccgtaga ccatttgtga
     3841 aatagcgttg agacgctcct tctcatcttt ccctgttgct atctgaatgg catagtggtt
     3901 ttcagatgcg acttgagaga tgccacgtag aaccgatgga aagaaaggat tctggtagaa
     3961 ggcgtctgag tcatcaggaa gaactaatcc gataacctga gtatagctgc ttaccaagct
     4021 acgagcgttg aggtttgggt ggtagttgag ttccttcata gctttgcgaa cgcgtttttt
     4081 tgtttcgtcg ctaatggttg atttattttg aataacacgg gttacggttg aaggcgaaac
     4141 accagcagcc ttggccacgt ctttaatcgt aacgggcata aaaatctcct atttatggta
     4201 atttggatca cggaaatgtg ttttataaaa gatagtgacc agatacagaa caaaaagaat
     4261 attttgtaca gtaatcaggg ttgtcatatt ttggccaaat aatcccaaaa taagtgtaat
     4321 cagagtcggc aatcctaaac agttcaagat aaagtgatag cactctttaa aggttctaaa
     4381 tgaaaagagg cgtgatttct tagtgatata aaggagaaga ctagctccta gagagacgat
     4441 aaagaaattc aaaccaaaga ggaagctcgc accgagaact aggaagaggc tgatatagat
     4501 acgattttgt tggtaccagt ctttagaaat tgcttgggtc aagctgtctt tgcttttgaa
     4561 actctcagtc tgaatggctc ggtaagagat gcgggtcagt tccttgcttt ccttgctgat
     4621 gactagttca tttgtatcga aatgcagttg caagtcctta ggtaattcct tgatttgact
     4681 tggaccaatc acaacagaag gggcttgact agctgttcca gtataagtta atgtgccatc
     4741 gacaattgta gcatgttcag agagatcctg gacaacctca tttgtcagag gttcatagac
     4801 attatcgata aaagtttcta gcggataggt ctcctgggag ctgttttgga tagcaatggg
     4861 taccatagac aagctgataa ggaagatact ggtaaagaga agttgaaacc agttgagctc
     4921 gaaacgtttg gacaggggct tacgaaaccc ccaaatactt gaaaaatagg aaaatggata
     4981 tggaagcata ggtatctttc taaaaggtgt tttctatatg agtattatta tatagagaaa
     5041 tgcgctttat ttcaagtcta ggagaaaaat tgcttgctac aaggatatta tttacagtga
     5101 caattgctaa taatcaatga aaatcaaagt gcaaaccagg aagctagctg caggttgctc
     5161 aaagcacaac tttgaggttg gagataaagc tgacgtggtt tgaagagatt ttcgaagagt
     5221 ataaaatgaa aaagggtggc ggggataaat tatcccttgt cgccaccact tgtaagtcct
     5281 gaaacaaagt tcttttgtag aaagaagaag agaatacaga ttggaagggc gatgaggata
     5341 gcacctgctg agaagtaggc aatcttcaag tttttcgcat tgttaacgaa ggtttggaga
     5401 cctacggcaa cagtaaagta ttctttctca cgaagcaaga aactagagag gatgtagtcc
     5461 ccgaaaggtc ccatgaaggc ccagagagct tgtacggcaa ccattgggcg aacaagtggt
     5521 agaacaattt gccagaagcg gcggaagtgt cctgcaccgt ctagttttgc agattcgtct
     5581 aaagacattg gcactgtatc gaagtagcct ttcatgagcc aagcattcat cgggatacca
     5641 ccaccaacgt agaggaagat gaggaaccag ttgtggttaa gggcgttcaa cataagcgcc
     5701 ataacgaaga aggctgtcaa agcggccata gttggcacca tttggatgat caagaagaag
     5761 accaaacttt gtttacgagc caagaagttg taacggctgt aagcataacc agcaagtacg
     5821 atgatacttg tttgaacagc catggtaatt aaggcgataa tcaaagtgtt gaggtaccaa
     5881 gtaccgtaca aggtttcagt gaagaggcct ttaaagttat caaaattgag gtcgatatta
     5941 gtatctagtt taaaggctga gacgttacct gctttaaagg ctgacataat ggtaatcaac
     6001 agtggataga taattacaat tgatagacca atcaggtaaa ggtaagtaag gctttgagtc
     6061 agtctacgtt tgagtttaat tgagttattc atcttagacg tcctccatat caaatgcgtg
     6121 tagtttcttg aatgcgatca tagagattga gatgacaatg atagagataa tcaaggtaac
     6181 agctgccgcc attgagtatt gaggagatgt acctgttgtc aaacggtaga tccatgagat
     6241 caagatatcg gttgaaccag ctccacctcc gacactacca ggtcctccac cattgaagag
     6301 gtacatgata gagaagttgt taaagttgaa ggtgtattgg ctaatcaaag taggtgccgc
     6361 aacagccaaa atcattggga aagtgatgtt gcggaatttt tgccaagcgt tggcaccgtc
     6421 aatataagct gcttcgtaaa ggtcgttagg aatagattgc aagataccca aagtcaaaac
     6481 gtagatgtat gggaatccga gccaaccttg catcataatc aaggcaatct tagtccaagt
     6541 tgggtctgtt ttccaaggaa taagagctcc atcaaggaaa ggaaggaatt tagccaagat
     6601 tggcaatact tgagtgttga tagcaccgac actatcgtta aacatgtttg agaatgtcaa
     6661 gatagtgatg aaggctggga cagcccaagg aagaaggaaa ataacaccaa agatacgttt
     6721 tcctttgata aatggttggt tggcaatgat agctgtgaag ataccaatta cgatttgtaa
     6781 agtagaagct gccaaagccc aaatgatagt ccaagaaaga acagaaccaa aggcagaacg
     6841 gaaggtactc aagctccaaa tgtttgtaaa gttggtcaaa ccaacccagt ccaacaactt
     6901 gtttggtggc aagtgttgga agtcgtagtt ggtaaaggcg atcatcaagg ttacgataac
     6961 tgggaagata atcgcgaagg tcatggcaac ataagatgga atgatcaaga ggtaagggaa
     7021 gccattttca taaatccctt tgatcatgtc tttgagtgtg cgtggaactg gaattccatt
     7081 gttaatgcgt tttgcaatcg tatgtgcatc tttgatattt gagaaataaa agagtacata
     7141 aacgattaca aagattagat ggaaggcacc acgaatcagc ataaagaggg aattatcacg
     7201 acctggtttg ttaccaagag tgatgaggtt gctcaattca ggggttgcaa gtgctaggaa
     7261 gtaaaggaca aatacgatgg ttacaccaag gaagataaaa cctttggctt tttgtttatt
     7321 gtaaatctgt cctaacccag gaatgataga cagcagggct gctttactag gttgttgctt
     7381 ttccatatta actcctttca taggatacta cttttttata agaaagctaa attatttgtg
     7441 tctctattga taaattcaaa gggggatttg atttccaccc cccttgaaca aattttttat
     7501 tcaccaaatt tttgtttgat tgtttctttg atcaatgtta cagcatcgtt agcagctgtt
     7561 ttagcatctt tttgaccact tacagcatca aagagcatat ttttcgctgg atcccaaact
     7621 gcagacattt gagagatgtt tggcagtggt tgagtgttct tgaactgttt gataacagct
     7681 gttgtcaact catcgttttt accttcagcg tatgaacgag cctcagtatt agctgggatt
     7741 tcgttagtct tatcatataa tactttttgt tgttcagttg caacaaggaa gtctacaaat
     7801 ttttgagaag cttcaaggtt cttaacggct tgaggaatga cccaagcttt accaccaccg
     7861 aatgcagcat attcttttcc atttggaaga gttgggatag ttgcaactcc gtagtttact
     7921 ttagcatctt taaaggcttg agctttccaa ggtccgtcga tgatagcagc tgttttacct
     7981 tcttggaatt gagtttggat taagtttcca gcaccttctg tatcttgcat acctttaggc
     8041 catttttcgt accaagattt agcgtaattg atacctacga tagaaccgtc gtttgcaaga
     8101 ccgatgtctt tagcgtcttt accgttttgg ccaaagacgt aagcaccgtt accggcaaga
     8161 agtccatatg tatagtagaa gtttgtccag tcagctagga aggcagtagt tttaccatct
     8221 tcaccagcga atgcgtattt gctatcttta gcaaggtttt ccaagtcagc aaatgttttt
     8281 ggagcatctt tcaccaagtc tttgttgtag tacataacaa gtgactcgat aacggcagga
     8341 gcaccgtaaa ctttaccatt agcagctgtt acaagagatt tagttgtgtc gtctgtttta
     8401 gcaccatcgc tcaatttcac ttctgaaagt tgtccgtcag aaccaaggct acctacacgg
     8461 tcgtatggag ccatcataac atcagggaca ttaccagatt ggttgtcaag agaaagttta
     8521 tcaagacctc ctagagcatc accagtttta agagtgactt ttactccagc ttctttttca
     8581 taagctttag caacctcttc aatatagctc ttatatccct cgtctacata tacagtgagt
     8641 tctttgactt cagatgaacc agaatcagca ggcttatcag cagttttgct tccgcaagct
     8701 accaaaagca agctagcaag tgtagcagtt ccaagcaccg cagtgctctt cataaattta
     8761 gatgacatag tgtattcctc ctaaagaata gcaagtttta ttgataagga aacgcaaacg
     8821 ttttccttta tgagcttagt atagcacaaa tagaaaacgg ttgcaagtat tttttgtaaa
     8881 aattttaaaa aatttttaag cttgatttga tagcataatt ttgcatttta atagaagaaa
     8941 agtatgaaat agataagaat acagtatttt taataaaaat atatggaatc tgtctaaaga
     9001 gggaaatcag gaggggctac ctccctgttt ctaatctata tctattttct atagacgttt
     9061 gtgctttgtt acatataaat tcaagctccc taaggaggtt ttatactttg tagactgtct
     9121 cgtgagagtc aaaccttagg attagatagt tttaagttat ctttgctaaa atgagttagt
     9181 ttccttaaaa ataatcaaaa aagtttttta aaaacgcttg caattatgct tgaaaaggag
     9241 tatacttata agtaacgcaa acgtttgcgt ctgcaaaata cgcaacgttc cattatttta
     9301 acacacgagg tgctattatg aaaaaacgtc aaagtggtgt gttgatgcac atctcttctc
     9361 ttccaggagc ttacggaatc ggatcatttg gtcaaagtgc ttacgacttc gttgatttct
     9421 tggtccgtac aaaacaacgt tactggcaaa tccttccatt aggagcaact agttacgggg
     9481 attctcctta ccaatctttc tcagccttcg caggaaacac tcattttatc gatttagata
     9541 tcttggtgga gcaaggtttg ttggaagcaa gtgaccttga aggagttgac tttggtagcg
     9601 atgcgtctga agttgactat gctaaaatct actatgcacg tcgtcctctt ttagaaaaag
     9661 cggtgaaacg tttctttgaa gtcggagatg ttaaagattt tgagaaattt gctcaagaca
     9721 accaatcatg gcttgagctc tttgctgagt atatggctat caaagagtat tttgacaatc
     9781 ttgcttggac tgaatggcca gatgcagatg ctcgtgctcg taaagcttca gcacttgaaa
     9841 gctatcgtga gcaattggca gacaagttgg tttaccaccg tgtgactcaa tacttcttct
     9901 tccaacaatg gttgaaattg aaagcttacg ctaacgacaa ccacatcgaa atcgttgggg
     9961 acatgccaat ctacgtagcg gaagattcaa gtgatatgtg ggcaaatcca catctcttca
    10021 aaacagatgt caatggtaag gctacttgta tcgcaggatg cccaccagat gagttttctg
    10081 taactggtca gctttggggt aacccaatct atgactggga agcaatggac aaagacggct
    10141 acaaatggtg gattgaacgc ttgcgtgaaa gcttcaaaat ctacgatatc gttcgtatcg
    10201 accacttccg tggcttcgaa tcttactggg aaatccctgc tggttccgat acagcagcac
    10261 ctggtgagtg ggtgaaaggt ccaggctaca agctttttgc agccgttaag gaagaacttg
    10321 gtgagctaaa catcatcgca gaagaccttg gcttcatgac agatgaagtg atcgaattgc
    10381 gtgaacgtac tggcttccca ggaatgaaga ttcttcaatt tgccttcaac ccagaagacg
    10441 aaagcattga tagcccacac ttggcacctg ctaactcagt tatgtacaca ggaacacacg
    10501 ataacaatac ggttcttggt tggtaccgta atgagattga tgatgcgact cgtgagtaca
    10561 tggctcgtta cacgaaccgt aaagaatacg aaacagtggt acacgctatg cttcgtacag
    10621 tattttcatc agttagcttt atggcaattg caactatgca agatttacta gaattggatg
    10681 aggcagctcg tatgaacttc ccatctaccc ttggtggaaa ctggtcttgg cgtatgactg
    10741 aagatcaatt gacaccagct gtcgaggaag gtttgcttga cttgacaaca atttatcgcc
    10801 gaattaatga aaatttggta gatttaaaga aataagacaa taatcaggag acaactaaac
    10861 atgttatcac tacaagaatt tgtacaaaat cgttacaata aaaccattgc agaatgtagc
    10921 aatgaagagc tttaccttgc tcttcttaac tacagcaagc ttgcaagcag ccaaaaacca
    10981 gtcaacactg gtaagaaaaa agtttactac atctcagctg agttcttgat tggtaaactc
    11041 ttgtcaaaca acttgattaa ccttggtctt tacgacgatg ttaaaaaaga acttgcagct
    11101 gcaggtaaag acttgatcga agttgaagaa gttgaattgg aaccatctct tggtaatggt
    11161 ggtttgggac gtttggctgc ctgctttatc gactcaattg ctactcttgg tttgaatggt
    11221 gacggtgttg gtcttaacta ccactttggt cttttccaac aagttcttaa aaacaaccaa
    11281 caagaaacaa ttccaaatgc atggttgaca gagcaaaact ggttggttcg ctcaagccgt
    11341 agctaccaag taccatttgc agactttact ttgacatcaa ctctttacga tattgatgtt
    11401 actggttatg aaacagcgac taaaaaccgc ttgcgtttgt ttgacttgga ttcagttgat
    11461 tcttctatta ttaaagatgg tatcaacttt gacaagacag atatcgctcg caacttaact
    11521 ctcttccttt acccagatga tagtgaccgt caaggtgaat tgctccgtat cttccaacaa
    11581 tacttcatgg tttcaaacgg tgcgcaattg atcatcgacg aagcaatcga aaaaggaagc
    11641 aacttgcatg accttgctga ctacgcagtt gtccaaatca acgatactca cccatcaatg
    11701 gtgattcctg aattgattcg tcttttgact gcacgtggta tcgatcttga cgaagcaatc
    11761 tcaattgttc gtagcatgac tgcctacact aaccacacaa tccttgctga agcgcttgaa
    11821 aaatggcctc ttgaattctt gcaagaagtg gttcctcact tggtaccaat catcgaagaa
    11881 ttggaccgtc gtgtgaaggc agagtacaaa gatccagctg ttcaaatcat cgatgagagc
    11941 ggacgtgttc acatggctca catggatatc cactacggat acagtgttaa cggggttgca
    12001 gcactccata ctgaaatctt gaaaaattct gagttgaaag ccttctacga cctttaccca
    12061 gaaaagttca acaacaaaac aaacggtatc actttccgtc gttggcttat gcatgctaac
    12121 ccaagattgt ctcactactt ggatgagatt cttggagatg gttggcacca tgaagcagat
    12181 gagcttgaaa aactgttgtc ttatgaagac aaagcagctg tcaaagaaaa attggaaagc
    12241 atcaaggctc acaacaaacg taaattggct cgtcacttga aagaacacca aggtgtggaa
    12301 atcaatccaa attctatctt tgatatccaa atcaaacgtc ttcacgagta caaacgccaa
    12361 caaatgaacg ctttgtacgt gatccacaaa taccttgaca tcaaagctgg taacatccct
    12421 gctcgtccaa tcacaatctt ctttggtggt aaagcagctc cagcctacac aatcgctcaa
    12481 gatatcattc acttgatcct ttgcatgtca gaagttattg ctaacgatcc agcagtagct
    12541 ccacacttgc aagtagttat ggttgaaaac tacaacgtta ctgcagcaag cttccttatc
    12601 ccagcatgtg atatctcaga acaaatctca cttgcttcta aagaagcttc aggtactggt
    12661 aacatgaaat tcatgttgaa cggagctttg acacttggta ctatggacgg tgctaacgtg
    12721 gaaatcgctg agttggttgg agaagaaaac atctacatct tcggtgaaga ttcagaaact
    12781 gttatcgacc tttacgcaaa agcagcttac aaatcaagcg aattctacgc tcgtgaagct
    12841 atcaaaccat tggttgactt catcgttagt gatgcagttc ttgcagctgg aaacaaagag
    12901 cgcttggaac gtctttacaa tgaattgatc aacaaagact ggttcatgac tcttcttgac
    12961 ttggaagact acatcaaagt caaagagcaa atgcttgctg actacgaaga ccgtgacgca
    13021 tggttggata aagtcatcgt taacatttct aaagcaggat tcttctcatc tgaccgtaca
    13081 atcgctcagt ataacgaaga catctggcac ttgaactaat actcttcgaa aatctcttca
    13141 aaccacgtca gctttatctg caacctcaaa gcggtgcttt gagcaacctg cggttagctt
    13201 cctagtttac tctttgattt tcattgagta taagatacaa atttatacta atacatcttg
    13261 taaaaaagcg agtttcgatt gaaattcgct tttttaatga tgtagatttg ggtcaatctt
    13321 gtctaaaaat agggaaatcc tagatacagt gaaggcttta aatgctggtt tttactgtcc
    13381 tcagccttat attttttcgt agttgattac ctcatacctc ttgtattcgc ttacataaag
    13441 tattataata taattgtagg aaagaaggtg tttttatgat atacacactt aaattggtgt
    13501 tgtttattac ctttcttgta ataagcttgt tacctgataa gatttttgga aaaaataaaa
    13561 aaatttggaa aatagttttt gcaatattga cggcagtggc agcattgtca tttatgtact
    13621 aagttatttt aagaatgtag ggaaataaac cctacattct ttttagtttt ttctgttttc
    13681 taaattctat ttatccaagc gcttcaacat ttcttgcttc ttcgcttcaa gttctgcacg
    13741 cttttcttcg atttcggcat gttttttctc gagttcagaa caacttgcac cattgctaaa
    13801 ttcttttcgc catcaggaga tagggtgagt cgacatgtct attactcacc caaagcagtc
    13861 ctacaaagca ggaattttct gttacttttt tggaaatagt aacgtttata cagctttgac
    13921 acttcgtatc aaagcgccaa acacactccg agggatttac agaaagcaga aaaggaatga
    13981 tctggtataa gatcattcct tttctctctt tttctttaag taattatata caatgtacga
    14041 cgaagtcgtc attgcaatgc tgatccacca cctaaaggaa actttaaaca acattgataa
    14101 gataaagaat ataaacaacg aaaatacgtt atacccaatt aattttattg tatatctcat
    14161 gattaaaagt taatccttcc gttgttagga atggcatcat ttttatccca taattgtgct
    14221 aaataagtcc ccggtgataa taaatttata gcaaattcta aagcaacatc atttacaaac
    14281 caactaccta gatatctaga aattgctgaa cgaatagcac tttttgctgc atgttttcct
    14341 tttactttaa ttagatttgc aaggcctgca gtagttcctc ctaatgctaa agctattgca
    14401 gtatctaata gagcacccat ttgattaact gtaatacctt gccaagctgc tctaaatgga
    14461 gagtatgtag gtgggattgt ataatcgcct tgtaattgtc ggttaattac ttctttgatc
    14521 cattgttgtg agacgtctgg atgaaaagat tggatttcgt ttgcaagtgt attgatttgt
    14581 tcttctgtta gagaagtgac aggttgaagt tccatatttg tttcaatttg tgatacttgt
    14641 tcagaagcgt atacagctga aacacttgga atcgctgata caattaacac aattgacgtc
    14701 aaaaaaaccg aaataaattt cattaatttg ttcatgagct tttctccttt ttatttgtat
    14761 ctgcttacat tttatcatat gctgttatta tagtcaaaaa aatatgctat tatgttaaaa
    14821 aaatattttt caaaatataa atggacggat ttattttgga ttttatttgt tattttgacc
    14881 tgcctctata ttggtaacca tgatttgttt actctcaatc atcaagaatt ctcttttcgt
    14941 ggtagcgttt ggggtctggt actggcctta tatcacttac tattcattga taagtttgtt
    15001 atatcgaatc gaaaataaag attagagcta tgcttgactg tgtactttta ggattgattt
    15061 tggaggaaga ttttgtctct attatttatt attttaaatt tatttatttt gtataagatc
    15121 tattctttga ggcgggaaaa atcgaaatac ttgatttata cggcctatat catatttggg
    15181 gtaaatgtag tatatggtat tcaatggtta ttaagagaac tgatttcaac tatttcccct
    15241 taatgtgtat ggaaactata acaaaacgca taagattaag gtttgtgtac ctgttcttat
    15301 gcgtttttat aatattgaag attttcggta agttttatac ctttgggaag tctagtttag
    15361 aatgctttcc caaccaaaat ctctgcttcg atggtaatct ctgtcagttg gctccagtca
    15421 atcttgctct ggtcaacgtg aaagaggaga ggagtcatac tgagtagggc ttggagttgt
    15481 tctgctgtga tagtcttagt cagagaggca gtttgactag ataggatggt aaagtgttcc
    15541 tggaaatgct ccttgatatc ttggttagaa tactccttgt ttgtcagctg gtcctgtact
    15601 ctttgacgga tttctttgag gtgattttca gttgggataa cctttatcaa gataccgtct
    15661 ttggataaaa cgcgacgaaa ttctccatag ttggcaggtg agaagatatc aagcagaata
    15721 tccatgttag cgtcttttat aggaagtcgt gccaagtcgc caacgaacca attgactgcc
    15781 cagttgggtt cacttttagc agcgatttgg actgaatctt tggagatgtc aaaggcatag
    15841 aaagtttttt cagagtgact ttcttgtagt ttgcgagaat agaatccttc accacaaccg
    15901 atatccaaaa ttgttgtggt agtttttgag cttgcaagca agtcagatac agcatctaag
    15961 atagcttggt aaaagccggc ttctaggatt tgttgacggt tttgaaaatt ttccttgtca
    16021 tagttagcag attgcttgat ttgaggtgct agattgacat agccaaattt cgccaagtca
    16081 aaagaatgac ggttgcagca cttgaaatta gtctctaaca gagtcagatt ttcttgacag
    16141 ataggacagg caaaggcagt cgcagaagca aaacgctgaa gtttgggctt gagatttgta
    16201 ttcatagttt aagtgtatca aaagaggcaa atgaaagcaa ctttaggaat aagtagattc
    16261 agtagaaata aaactaattc tccaatttat agaatgaaat tgcttttata tctaaattgc
    16321 tatataataa tgataaggag gaaataagta tgttaaaaga agtattaacc gttgcaaaag
    16381 ttgcgaaaaa atcttcatta tttttgggtg gtgtcgcatt tggtaccctt ggtttgaaaa
    16441 tcttagcaag taaggaagct aaaaaaggtt attctaaagc tttggctaag gcttacaagt
    16501 tgaaagacga gctagatgca tctgtttctg ttgtgaagca acatggagac gatgtcttgc
    16561 aagatgccaa atatttgtac gagcaagaga aaaaagaaga gcaattagat agccttatag
    16621 gtgaataata tgtcttttaa agtgctacat agaggatacc aacatatccg actatcatct
    16681 tctttttcac ttaccttgga tattcaagac tatcttcgtt ccttggcgag agatgaaaag
    16741 gggattgagt ctatccagtt ttacatggat caacagcact ttactctacg cataaaagaa
    16801 ggcttttctg tattagataa tgcagaagcc tttttaaaaa gaattgataa agggaaagtt
    16861 tctgagttga tgactcttcc cattcgtaga gaagagagtg cttattctat tgtttcaggt
    16921 gcagcggtta agcgtgtact ttttcgtagt tttgtgccgt atcctattcg ctatatatgg
    16981 acttgttatc aggctttggg ttatattaga gaagcctatc aaacactagc gcgtaaggaa
    17041 ctaacgatgg aagtcttgga ctgttcggct attttattgt ccttgtttat gaaccaatcc
    17101 aagacagcta gcaatatcat gtttatgctt gatttgggga atcatttaga tcagtggtcc
    17161 ttgaaaaaaa ctgcaacaga tttagaacag agtcttcttg caaaagagag cgatgtattc
    17221 ctagtacagg gcgatacggt tgttagtatc aagagttccg atgttcaaat aggagatgtc
    17281 ttgatcttat ctcaaggaaa tgaaattctg tttgatggac aagtagtttc aggtttaggt
    17341 atggtcaacg aaagttcctt gacaggagag agttttccag ttgaaaaaag agagtctgat
    17401 ttggtttgtg caaatacagt attagaaact ggagagttac gcattcgtgt aacagataat
    17461 cagatgaaca gccgtatttt acagctgatt gagttgatga agaaatctga agaaaacaag
    17521 aaaacgaaac aacgctattt catcaagatg gcggataaag tcgtcaaata taatttcttg
    17581 ggggctgggc tgacttacct attgacaggt tctttttcta aggctatttc tttcctattg
    17641 gtcgatttct cctgcgcttt gaaaatctct actcctgtag cttatttgac agttatcaag
    17701 gaagggttga accgtgaaat ggtgattaag gatggagatg ttctggagaa atatctggaa
    17761 gttgatactt tcttgtttga taagacagga acaatcacaa ctagttatcc tatagttgaa
    17821 aaggtgttac cttttggaga ctatagtgag gaagatattc tcagaatcag tgcctgtctt
    17881 gaggaacaca tttatcatcc tattgctaat gccatcgtca agcaagctga gatagaggga
    17941 attgaacatg aggaaatgca tgggaaactc caatatatcg caagcaaggg gatcaaatct
    18001 catatagatg gccaaccagt tcttattggg aattatgtct tgatgcagga tgagcagatt
    18061 catatcagtt cagaacaaaa tgctttaatt gaagagtaca agagtcacta caatctctta
    18121 ttcttggctt atcaaaatga attgattgga atgttctgca ttcatactcc tttgagaaaa
    18181 gaagcaaaaa cagccttgga taaacttaag gcacagggga aaaaattgat tctggcaaca
    18241 ggagacacct tgattaggac agaggaatta gtcaaagatt tgccctttga tcaggtctat
    18301 acagacttga aacctgatgg gaaatttgag ttagtagaga aactgcagaa agcaggtcac
    18361 actattttga tggttggaga tggattgaat gactcagcgg ctttaactct atcagatatc
    18421 ggtgtggtga tgaatgagag tgcagatatt tctaagcaga tgagtgatat cttattgtta
    18481 gataatcgtt tggatttctt ccaagagttg gattcgttat catcatcttt gcaaacactc
    18541 atcaagaaaa atattcagga taccgttgtc gtaaatagta gtttgattgg ctttggctta
    18601 tttaattggt tcagtccttc aaatctctct atcttacata atctaacaac cttgcgcatt
    18661 gtcctgcgta gcctgtctat taaaaataga tagatgagag ttattaacag caaaaaggag
    18721 ttacctttct cgaggttaac tcctttgttt atagataaat gttgaatagt ttagtaagtc
    18781 aatacaaagt attttttctt cccacgacgg ataacagtca gttcattttc taacttatca
    18841 gcgtcactca agacatagtc aaggtcttgg atgcggtcgc cgtttacgta gatggctccg
    18901 ttttggacgt cttcacgggc ttggcgtttt gagttaacta taccagatga gacgagcagt
    18961 tccacgatat tgttgttttc gtctgcctgt acttggtagt ttggcacacc acgaagtcct
    19021 tgtttgagct ctttgacaga aaggtttttg atgtttcctg caaagagttg ctcagtgatg
    19081 ttaagtgctt ctttgtaggc ttcttctccg tgaacaagtg taacaacttc acgagccaag
    19141 actttttgag ccaagcgttc gtgtggcgct gcttcaaatt gtttacgaat atcttcaatc
    19201 tcatcaagtg acaagaaagt aaagattttc aagaagcgaa cagcgtcagc gtccatcacg
    19261 ttcatccaga attggtacat ttcgtatgga gaagtctttt cgggattgag ccagacggca
    19321 tttccttctg atttaccaaa ttttttacca gttgcatctg tgattagtgg aacagtgata
    19381 acgtgaccag tcttgtccgc cttacgacga agcaattcgg taccagctgt catatttccc
    19441 cactggtcag aaccaccgat ttgaagagtg acattatggt cttggttaag gacgaagaag
    19501 tcgtaccctt gcatgatttg gtaagcgaac tcagtgtaag aaattcctgt ttcgatccgt
    19561 tttttaacag attccttact catcatgtag ttgaccgtga agtactttcc aatgtcacgg
    19621 aggaagtcaa tgaagctgat gctgccaaac cagtcgtagt tgttgaccat gacagccttg
    19681 ttttcgccat tttcaaagtc aagaaaacga gaaagttgtc cttggataga cttgacccag
    19741 ccatctactg tgtcttttgt ttggagacta cgttcagcat ctttgaagga cggatctccg
    19801 atgagacctg tagcaccgcc aacgagcgca taaggtttgt gacctgctag ttgcaagcga
    19861 cgacttgtca agattgcgac aaggtggcct aggtgaaggc tgtcagcagt tggatcgtag
    19921 ccagtataat aagaaacttg accttcttct agggctttac gcaaagcttc ttcatcagtc
    19981 gtttgaaata tcaaaccacg ctcttttagc tcatcaaaaa tgtgcatgtg tcttttctcc
    20041 tttttaaaat tattgtttct acctattgta tcacaaactt gggcaatagc ctagcagaat
    20101 agggaagaaa gtggctattt tattgaaaat ttcccttttg tggtataata gataaagtga
    20161 ggaaatccat gcaaaatcaa ttaaatgaat taaaacgaaa aatgctggaa tttttccagc
    20221 aaaaacaaaa aaataaaaaa tcagctagac ctggcaagaa aggttcaagt accaaaaaat
    20281 ctaaaacctt agataagtca gccattttcc cagctatttt actgagtata aaagccttat
    20341 ttaacttact ctttgtactc ggttttctag gaggaatgtt gggagttggg attgctttgg
    20401 ggtacggagt ggccttattt gacaaggttc gggtgcctca gacagaagaa ttggtgaatc
    20461 aggtcaagga catctcttct atttcagaga ttacctattc ggacgggacg gtgattgctt
    20521 ccatagagag tgatttgttg cgcacttcta tctcatctga gcaaatttcg gaaaatctga
    20581 agaaggctat cattgcgaca gaagatgaac actttaaaga acataagggt gtagtaccca
    20641 aggcggtgat tcgtgcgacc ttggggaaat ttgtaggttt gggttcctct agtgggggtt
    20701 caaccttgac ccagcaacta attaaacagc aggttgttgg ggatgcgccg accttggctc
    20761 gtaaggcggc agagattgtg gatgctcttg ccttggaacg cgccatgaat aaagatgaga
    20821 ttttaacgac ctatctcaat gtggctccct ttggccgaaa taataaggga cagaatattg
    20881 caggggctcg gcaagcagct gagggaattt tcggtgtaga tgccagtcag ttgactgttc
    20941 ctcaagcagc atttttagca ggacttccac agagtcccat tacttactct ccttatgaaa
    21001 atactgggga gttgaagagt gatgaagacc tagaaattgg cttaagacgg gctaaggcag
    21061 ttctttacag tatgtatcgt acaggtgcat taagcaaaga cgagtattct cagtacaagg
    21121 attatgacct taaacaggac tttttaccat cgggcacggt tacaggaatt tcacgagact
    21181 atttatactt tacaactttg gcagaagctc aagaacgtat gtatgactat ctagctcaga
    21241 gagacaatgt ctccgctaag gagttgaaaa atgaggcaac tcagaagttt tatcgagatt
    21301 tggcagccaa ggaaattgaa aatggtggtt ataagattac tactaccata gatcagaaaa
    21361 ttcattctgc catgcaaagt gcggttgctg attatggcta tcttttagac gatggaacag
    21421 gtcgtgtaga agtagggaat gtcttgatgg ataaccaaac aggtgctatt ctaggctttg
    21481 taggtggtcg taattatcaa gaaaatcaaa ataatcatgc ctttgataca aaacgttcgc
    21541 cagcttctac taccaagccc ttgctggcct acggtattgc tattgaccag ggcttgatgg
    21601 gaagtgaaac gattctatct aactatccaa caaactttgc taatggcaat ccgattatgt
    21661 atgctaatag caagggaaca ggaatgatga ccttgggaga agctctgaac tattcatgga
    21721 atatccctgc ttactggacc tatcgtatgc tccgtgaaaa gggtgttgat gtcaagggtt
    21781 atatggaaaa gatgggttac gagattcctg agtacggtat tgagagcttg ccaatgggtg
    21841 gtggtattga agtcacagtt gcccagcata ccaatggcta tcagacctta gctaataatg
    21901 gagtttatca tcagaagcat gtgatttcaa agattgaagc agcagatggt agagtggtgt
    21961 atgagtatca ggataaaccg gttcaagtct attcaaaagc tactgcgacg attatgcagg
    22021 gattgctacg agaagttcta tcctctcgtg tgacaacaac cttcaagtct aacctgactt
    22081 ctttaaatcc tactctggct aatgcagatt ggattgggaa gactggtaca accaaccaag
    22141 acgaaaatat gtggctcatg ctttcgacac ctagattaac cctaggtggc tggattgggc
    22201 atgatgataa tcattcattg tcacgtagag caggttattc taataactct aattacatgg
    22261 ctcatctggt aaatgcgatt cagcaagctt ccccaagcat ttgggggaac gagcgctttg
    22321 ctttagatcc tagtgtagtg aaatcggaag tcttgaaatc aacaggtcaa aaaccaggga
    22381 aggtttctgt tgaaggaaaa gaggtagagg tcacaggttc gactgttacc agctattggg
    22441 ctaataagtc aggagcgcca gcgacaagtt atcgctttgc tattggcgga agtgatgcgg
    22501 attatcagaa tgcttggtct agtattgtgg ggagtctacc aactccatcc agctccagca
    22561 gttcaagtag tagttctagc gatagcagta actcaagtac tacacgacct tcttcttcaa
    22621 gggcgagacg ataattctct aaatgaagtg gccaatcaat ggattgccac ttttttcctt
    22681 tcgtgttaca ataagggtat gaatcagtat cagaaaaaga ttgttaacgg aaaaatttat
    22741 tcgctcctat ccggcttaat atggggaatc tgtggaattt taggagagta cttctttact
    22801 cattatcagg tgtcttcggg ctggattacc tctatgcgtt tgacactggc agggagtctt
    22861 gtactcattt ggtctgcaat acaattaaaa tcgcaagtgc tagatatttg gcgagacaag
    22921 aaaaattacc tgcccttttt agcctatgct attttgggga ttttttcagt tcagtatttt
    22981 ttctatctct gtttagaata ctcaaatgct acgacagcaa ctattttaca gtttattagc
    23041 cctgtcttta tcctctttta caatcgcttg gtttatcaaa aacgagcgtc aaaaagcgct
    23101 gttttctatg ttttggttgc catgctgggt gtttgcttga tggctacaaa gggagatctc
    23161 tctcagttat ccatgacgcc gctagctctt ataacaggtt tgctgagtgc catgggtgtt
    23221 atgtttaatg ttatcttgcc ccaacctttt gctaagcgtt atggttttgt tcctacggtt
    23281 gggtggggga tgattttggc aggtttgttt agcaatgtcc tctcgccggt ttatcagctt
    23341 tcctttactc ttgatatttg gagtatcttg atttgcctca ttatcgcttt ctttggaacg
    23401 gcttttgctt ttttcatttc catgaaggct gtgtccttgg tttctccttt ggtggtttcc
    23461 gttatcagtg ccagtgaacc tctctcttct gctctcttga gtgttttgtt cttaggatta
    23521 gtagtggatt ggtccctcct tctagctata gccttgatta ttttacccat gatatttttg
    23581 tctatagaag aagcgaaaga aagtagataa aaagtctttt cttaattcta aaagtgtgct
    23641 atactagaat agtcaataaa acacggggag atagttgtga agagtatttt taggttgtat
    23701 cggtaggggc ttgcttttac cgacagcacg ttttatctca catccctaaa aaatcatacc
    23761 taaaaacaga caaaaaggtt tcaaatttga ggcctttttt ggtagaatag gtatcattat
    23821 aacgaaccag gaggcaccta tgactgctac aaaaatgaac gctcaagaaa ttatccaatt
    23881 tatcgccaat gctgaaaaga aaaccagtgt caaagtaacc tttgaggggc aactcgcaac
    23941 tgctgtgcct agctctgttg tcaaactagg aaatgtccta ttcggagact ggaaggacgt
    24001 ggctccgctt cttgaaggtt tggtagaaaa tcaagattat gttgtcgagc aagatgctcg
    24061 taattctgca gttcctttgc tagataagcg tgctatcaac gctcgtatcg agccaggtgc
    24121 tattatccgt gaccaggtgg aaattggtga caatgctgtt atcatgatgg gagctgttat
    24181 caatatcggt gctgaaatcg gtgctggaac catgattgac atgggtgcca tccttggtgg
    24241 ccgtgctatc gttggaaaaa atagccacgt tggtgcaggt gcagttttgg caggtgtgat
    24301 tgagccagct agtgctgaac cagtctgtgt cggagacaat gttcttatcg gggctaatgc
    24361 agtggttatc gaaggagtcc aaatcggtag tggttcagtt gtcgctgcag gagctatcgt
    24421 tacccaagat gtcccagaaa acgtggtagt agcaggtgtt ccagctcgta ttatcaaaga
    24481 aattgatgcc caaactcaac aaaaaacagc gctagaggat gcgcttcgta ccttgtaatt
    24541 gtaaaagtaa aaaagaggcg gaaccctttt tccagcctct ttctgctata tcggaggaca
    24601 gatagatgtt agatttgatt cagactagac gagctttaca ccagattcca gagattggct
    24661 tggaggagtt caagactcag gcttatttgc tggatgtgat tgagaaattg actacgggca
    24721 aggattttgt tcaaattcgt acttggcgga cagggatttt ggtctacctg cagggaagtc
    24781 agccggagcg aaccattggt tggcggacag atattgatgg cctgcctatc gtcgaacaaa
    24841 caggtctacc ttttacttct caacaccaag gtcgcatgca tgcctgtggt catgattttc
    24901 atatgaccat tgccttaggc tgtcttgagc gcgcccttga ggagcaaccc aagaataatc
    24961 tgctctttct atttcagcct gctgaagaaa atgaagctgg tggtatgctc atgtatgagg
    25021 acggtgcttt tggagattgg ttgccaaacc aattctatgg tctccatgtt cgtccagatt
    25081 tgaaagtcgg ccagattgcg actaatactc atacactctt tgcaggaact tgcgaggtga
    25141 agatccgttt caaaggtaaa ggtggccacg cagcttttcc tcatgaagcc aatgacgcct
    25201 tggtggcggc tagttacttt gtgacccaag tgcagtcagt tgttagccgc aatgtcaacc
    25261 caatcgaggg agcagtggtg accttcggcg tttttcaagc tggaaccacc aacaatgtca
    25321 tcacagacac agctttttta catggaacta ttcgtgcctt gacacaggac atgagtctct
    25381 tggtgcaaaa gagggtaaaa acagttgcag aaggggttgc agctgccttt gatatggaag
    25441 tcgaagtgga actcaaacaa ggtggatacc tacctgttga gaacaatcca gccttggcgc
    25501 gtgaactgat ggacttcttt gacgagaaag acggaatcga gttgattgat atcgaacctg
    25561 ctatgacagg cgaggacttt ggttatctcc tttcaaaggt tgatggcgtg atgttttggc
    25621 taggtatcga tagtccctac gctcttcatc accctcaaat gagtcctaag gaagaagtct
    25681 tagctattgg ggtggctgcg gtgtctagtt tcctgaaaaa gaaggcagca gaatagaggg
    25741 cttgtctatg aaatcggaat tacgcaagca agtcttgcat gaaatgaagg ctatatctca
    25801 agagcaaaaa caggctatag accaagcttt aaccgagcga attttacaac acccctttta
    25861 tcaagaagcc aaggtcatcg caacctacct ctctttttct catgagtttc aaacgcggga
    25921 actgattgag caggcgctga aggacggcaa gaaggttttg acacctaaga cctatcccaa
    25981 ggggcgcatg gattttgtgg tctatgatcc gcaacagttg gtaaaaactt cctttgcctt
    26041 actggagcca cagggagatt tggaagtagt ggatgcatct cagattgatt tgattcatgt
    26101 tcctggcctg gcttttacga cggatggata tcggattgga tatggtggag gttattatga
    26161 ccgctatctg gaacattttt ctggtcgtgc tttgagtacg atatatcctt gtcaaattca
    26221 ggactttata cctgaaaacc atgatattcc tgttcaggag gtattaattg atgaaggaaa
    26281 tctttgatag acgttaccct gtgacgagtt tcttcctctt agtgacggcc ttggtatttt
    26341 tactaatgtt ggtcactgca ggcggaaact ttgacagggc agatacatta tttcgatttg
    26401 gagccatgta tgggccagct attcgcctct ttcccgagca ggtttggcgt ctcttgtctg
    26461 ccatttttgt tcatattggg tgggaacatt tcattgttaa tatgctttca ctttattatc
    26521 ttggaaggca ggtagaggag attttcggtt ctaagcagtt tttctttctc tatcttttat
    26581 caggaatgat gggcaatctc tttgtttttg tatttagtcc taaatcctta gcagcaggcg
    26641 cctctacctc tctttatggg ctatttgccg cgattattgt tcttcgctat gcaactcgca
    26701 atccttatat tcaacagcta gggcaatcct atctgacact ttttgtagtt aacattattg
    26761 gaagtgttct gattccagga atcagcctag caggccatat cggtggtgca gttggtggcg
    26821 catttctagc agttatcttt ccagttagag gagaaaaacg gatgtataat accagccaga
    26881 gattaggagc ggtagtcttg ttcgtaggac tcgccatttt gcttttctac aagggaatgg
    26941 gaatgtgacg aagttgaaag aaaatttgtg taatgaaaaa agataaggca ttttttgaac
    27001 cttatctttt tattttattt tattccttct cagtcaattc ttttccaagt tggatgaggt
    27061 aattcttcaa atcatctttg acttgtgggt gtttgagggc gtagtcgatg gatgttttca
    27121 tgaagccaaa cttgtctccg acatcgtaac gagccccatt gaactcacga gcaaatacac
    27181 gttgtgtttt attgagggtg tcgattgcat ctgtcagctg aatttcattt cctgcacctg
    27241 gagcttggtt ttcgaggatt tggaaaattt caggcgtgag gaggtagcgt ccgataatag
    27301 caaggtcgct aggagcgtcc tctggagctg gtttttcaac aaaggtttca acactgtaaa
    27361 gaccatcttt tccttcgcct tgcggagcaa taaccccgta agcagatact tcgtcatgag
    27421 ggactggcat gacagcgata gtagacgcgt gggtacgctc gtagtcatcc atgagttgtt
    27481 tggtaagtgg aacagccttt tcgtctgtga tatccatcaa gtcatcacca agcataacga
    27541 caaaaggttc atttccgacg aaagccttag cttgcaaaac agcatctccg agaccgcgtg
    27601 gatgagtttg gcggataaaa tgcagacgca tgtcagttgt tttatcaact agcttcaaaa
    27661 gatctgtttt ccctttttct ttgaggttat attccaattc gaagtttgaa tcaaagtggt
    27721 cctcaataga acgttttgat ttaccagtga caactagaat atcttcaata cctgatttga
    27781 gagcctcttc cacgataaac tggatagttg gtttgtctac gattggcaac atttctttgg
    27841 caagggcctt ggttgctggt aaaaatcgag ttcctagtcc agcagcaggg atgactgcct
    27901 ttctaacttt tgatgtcata aaaatccttt ctatagaggg ttaagaccac tcattttctg
    27961 ctttaaattc attgttcatg atgtcataaa tggcatcttt gatattggtt ccgtgataaa
    28021 taacttggta aatagcctgt gtaatgggca tatagactcc aagttcttgg gctagttcat
    28081 aggctgctcg agtcgttgaa attccttcga ttaccatgcc catattagct tctatatcag
    28141 ctagggattc tcctcgtccg agagcatctc cagctctcca gttacgagag tggatggaag
    28201 ttcccgttac gatcaaatct cccacaccag ataagccgct ataggtcaat ggactggccc
    28261 cgagtgctac ccctaggcgg gtgatttctg ctaaacctcg agcgatgatg gctgccttag
    28321 cattatcacc aaatccaaga ccatgtaaag ctccagcacc gacagcaata atatttttaa
    28381 gagcaccagc agtttcaacc ccgataacat ccgtattggt ataaagtcgg aagtagtgat
    28441 tactaaatag ctcctgaacg tattgagctg tttgtaaatc tttagaagca gcagtgatta
    28501 aagttaggtc acgcacaatg gtttcttccg catgactagg ccctgaaaca acgacaatat
    28561 cactgcggag ctgttcagga atttcttctt caaggatagt tgataatcgt ttatggctat
    28621 caggttctaa tccctttgaa gcgtgcatga tgatagcctt atggtccaag gtttgtgcaa
    28681 cttgttgggc aacaagtcgt gtcacttttg ttgggacaac aaacaaaatc gcatccacat
    28741 ctttcaatgt ttctgctaag tcggtgtagg caatgatatt ttcatctaga acgacatctt
    28801 taaagtagtg cttgttagta tgataggtat taatttcatt gatttgctcg ggaagatttc
    28861 cccaaatacg tacctcgtgt ccattgtcat ttaagacttg tgaaagggca gttccccaag
    28921 aaccaggccc caagacggcg acggtttgtt tttccatgat ttcctccttg atagagttct
    28981 ttccattatt ctatcatatt ctagaggatt ttgcacttgc attactgggg tatggtggaa
    29041 aaatacacaa agaccgagat gaagggataa actcttagtc tttagttaaa gtgagaagaa
    29101 atctgataga tagtttgatt cagtatatgc tataaataga ggtaaacaac tcaggaggtt
    29161 cttgtaggtt gcgagagttt ggcgaaaaaa ttaaaagatt acgtttggct aaaaaaatca
    29221 gtcgttcaga attttgtggt gatgagtctg aattaagtat ccgtcaatta attagaattg
    29281 aaaatggaga atccagacca acactaacaa agttaaaata tatcgctgaa cgtttggggg
    29341 gggtgaagat tacaagttga tgccaagtta tatagagttg gataaggaat acctagaatt
    29401 gaagtatttc ttgatgagga ctcctacata cgaagatgaa actatcgccc aaaagaaaga
    29461 gagtgttttt gctaagattt ttgaagagta ttatgatagg ctacctgagg aagaaagatt
    29521 tatcatccca aattattcat atctagcact agcgaactac acagttcaaa aattaccaga
    29581 aaagctagtt gaaatactgt ccttctggtg attttgctta atttctgatg ttcgagacat
    29641 gattgaggag atttgtcttg attttttcct aaaaaagggc agactcctcc cttggtttga
    29701 tgctcgattt ttaaaataag gtgacttatt ctgttaggca tgttttcccc tgccctctag
    29761 ctctatatgg aacagggagt atcagattta tctggcagat tgtatcaaat aaggcttgaa
    29821 actgttttga ataggcgtat agacttgaga atttgagaat atgtcgtcta gcagtagaga
    29881 catattttcc ggcaatatga aggaagagac gtcgaaaacg cttgatagtc aaggacttta
    29941 cttcatcacc agctagctgc tttaaaaaga ggtagagatt ataagccaga cagcccatca
    30001 tcatacgtac ttcattctta atcatggtcg aactatctgt cttatcccca aagaatcctg
    30061 ctttcctttc tttgataaag ttttcagcat tccctcgttc acgatagaat tgaaacagct
    30121 cctcactatc tacactgctt aaattgttca aatgaacttt tttacaacca taaaaaagag
    30181 cacttaatcg tactcttctc ttttaaggat tagttgaatt aattcaaatc cactagttct
    30241 cctgtttcta ggtagactag gcgttcacaa atgttagcaa tgtaatcagc gaagcgttcc
    30301 agatgtccta tgatataaag gtattgagtt ccattgggaa ttgaggtttc ttggtctttc
    30361 ataagtccaa tgatttcctt tgataaggca taataatatt ggtcaatctg ttcatctttt
    30421 tgagcaatac taatagcttt tgaggcttgg tgcaaaggaa aggcaaccaa taaatcggct
    30481 agcatgctga gggataattt acccatttgg tgtaactgtt cttcgtcagg ggctagttga
    30541 ttttctttta gttgcaaaac agctttggca atgcctgcca tatggtctcc catacgttca
    30601 aggtctgaac aagaagacat gatgctaatc acaaatcgaa ggtcagacac ttgtggctgt
    30661 tgcaaggcca acaaacgggc acaggtcaat tcgatagcgc tttgaccttg gttgatagca
    30721 tgatccttat tgataattag ctctgccatc tccttgtctt tggaggctaa ggccagtaag
    30781 gcttttgaag ctgtttcaag gacaagttgc cctagtccta aaaaggattg ttctaattca
    30841 tgcaattcta agtcaaattg atttctcata ggtttttcct tccttatccg aaccgtcctg
    30901 aaatatagtc ttctgtgcgc tgatcttttg gattggtaaa cacgtcaacg gtatctccaa
    30961 attcgcaaat ttctcctgtt aagaaaaaag cagttttatc tgaaatacgt gaagcttgtt
    31021 gcatgttatg ggtaacaatg ataatcgtat aatccttttt tagttgctga atgaggtctt
    31081 caatttttaa agtggagata gggtctaagg ctgaagtcgg ctcatccatt aacagaacat
    31141 caggttctac tgctaaagct cgcgcaatgc aaaggcgttg ctgctgaccg ccagataagg
    31201 acatggcact ctttttaaga tcatctttga cttcttccca aatggctgcc ccttttaaag
    31261 atttctccac taaggcatct aattgttttt tgtctcgaat accatgtgtc cttggaccat
    31321 aagccacgtt atcatagata gacatggcaa agggattagg ctgttgaaaa accatcccta
    31381 cacgcttgcg tagctgatta aggttgaatt tgctactata aatatcttgc tcatctaaga
    31441 ggacttggcc ttcaatatgg caagaaggaa ccaaatcgtt catccggtta agggttttta
    31501 gaaaagttga tttgccacaa ccagatgggc ctatcaaggc agtaatctgt ctttctggta
    31561 attgaatcga aatatttttt aaggcttgaa aatccccgta aaataagtct aggtgtctga
    31621 ctgaaaatgt tcccatacta ggaagctcct ttcacaagtt ttcgagataa taagcttgat
    31681 agagtattta tcattaaaac agtaataatc aaaatcacac cggtagcata ggcttcattg
    31741 acatgtagcc cctcacttga cagcatatac atatgcaggg ctagagaacg acctgaagac
    31801 atgagactac ttggcgtatt ggtagaggta cctaatgtat acatgagggc agctgtctca
    31861 ccaacgatac ggccaatagc tagtatcact ccagctaaaa tacctggcat ggcaactggt
    31921 agaacaattc taaaaacagt ccgtaactta cctgccccaa gtccataact tgcttgacgc
    31981 atgctatcac taacagataa aagggcttct tctgttgagc gaataatgac tggcaacacc
    32041 atgatgactg aggttaagat tcctgataac agagagtatt gaaaacctaa gaagactaca
    32101 aagaagagca tgccaaacag accaaaaaca atggaaggaa tcccagacaa ggtatctgag
    32161 gccaatcgca tgattttaac acaaagggaa tctttttttg tatattccac aagataaaaa
    32221 ccagcaaaaa tccctatggg caaggctaaa agaagagcac caaagaccag aataacggtg
    32281 gaaataatcg ctggcataag ggaaatgttc tcagaagtat aagtccaaga aaagagggat
    32341 agacttagat gaggtaagcc tttgatgagg ataaaaccaa tgattaaaaa gagagagcca
    32401 aaggttaaag ctgaaaaaca ataaacgaga agttttagca ggtatttact cataagatga
    32461 ttttcctttc aagtaggcaa agtaggcatt aatcaagaga ataaggaaaa agagaactgc
    32521 tgaggttgca ataagggctt ccctatgctg acctgatgcg taagccattt ccagaacaat
    32581 attggttgtt aaggttctgg ttcctgaaaa gagtccactt ggaataatcg gctggttgcc
    32641 tgccaccaaa ataactgcca tggtttcacc tactgcgcga ccgattccta aaataactgc
    32701 tgataaaata ccagatctcg cagctggcaa gatgacacta aaaatactcc gttcatgact
    32761 agctcctaga gccaagctac cagaataata cgttttggga actgttcgga tagcagattc
    32821 tgacaaactg ataatggttg gcaaaatcat tattcctaat agtaacgaag cggttaggac
    32881 actcatgcca tttcctaaaa aggttctaat ccaaggcacc aataattgta ggccgaaaaa
    32941 accataaaca atagatggaa tggccgccat caagttgata gctgatttta agaagccata
    33001 gacgggcttt ggacaataat aaaccataaa caccgatgtc aagatgcctg ttggcacccc
    33061 aatcacaatc gctcctaagg taattaataa ggaaccaacg atcattggta aaataccata
    33121 gcttgccgga atgttcgttg gcgaccaatc actgcctaat aaaaaacggg caaagccgta
    33181 gttagccatg aaaggtaagc cattactaaa aataaagaaa cagattagca aaatagctac
    33241 aacagctact gttgcactca tgaaaaaaat tgccctaaaa actgcttctt tgaaggcttg
    33301 ttttgtcaca tcttgtcctt tctagtgaag aaagtaaggg agatacgaca cctccctact
    33361 tgccttcttt atcttattgt acgatgaaac gtctgcatct ctttagagat ttatggagca
    33421 aacattttat ttaatcttgt cccaggtggt taatttgcca ctaaaaacgt ctgcaagttc
    33481 agccatactg acttggcttg ccttattgtc attattgacc acaacagcaa taccgtctaa
    33541 agcaatagca tcatgggtga gactcttacc ttcttcagga gttaattccc tagaaaccat
    33601 accaatatca gcggttttct ccttaacagc ggtaatacct gctgaagacc cattagaggt
    33661 aatatcaatc gtaacttctg gattttcttt tttataagct tctgctaatt tttccattaa
    33721 agaagatact gaagtggaac ctacaacaga caacttgcct gataagtgtt ggcttgtata
    33781 ttctgtggtt tcggttttag cttcaataaa tttattatct gtgaccactt gttgaccttg
    33841 tttggagtgg ataaagctga taaaatcttg acctagcttg gaaagattag aagaccaaac
    33901 aatgttgaag ggacgttgaa gagggtattc accatctaaa actgtgtctc gactagcctt
    33961 gacaccatca atctctaaag ccttgacaga tttcgttaaa gatcccaagg agatgtagcc
    34021 gatagcatta gcattccctt gaactgctga gagaacacct tctgtactat tttgaatcac
    34081 agctgttttg gcagtgttgt caattttttt atcaccgtct tttttgagaa tccctgtgat
    34141 ttctgtgaag gcaccccgtg ttccagagcc attttctcgt gaaatcacct caatcgttcc
    34201 tgaagctgac tgtttggaag cagctgactg attgccacag gcaacaagcc caaatcctga
    34261 taagccaatg gctgcaagag taagcatttt tttgaatttc ataataatca cctttatctc
    34321 tatgtatttt tcttgtgtag gcttactaca tttatagtct aacaagtctt tgtaaaggtt
    34381 tatccctgat tcatgtaaag attgtgtaaa gaatcaaaaa aagccacttt tgaaaaatgg
    34441 ctgctcctaa aaatagcttt aaaaattatt agtcctgtgc gaaagattgg ttaggaagaa
    34501 aaatcgtgaa gcaactgcct ctgccaagct gactcgtcac cgtgacttgg ccacctaata
    34561 attgactgag ttctttgaca atggcaaggc caagaccagt gccaccagtt tgtctgcttc
    34621 gacctttatt aactcggtaa aaacgttcaa aaatacgatc ctgctctaat tgactaatac
    34681 caatccctgt atctgataca gaaatcttaa tgccttcgtt caccttttgg gtcttgacct
    34741 caatttttcc cccttgttca gtgtaacgga tggcattgga taaaagattg agtaagattt
    34801 gggaaagtaa ttgactatct gatacgaggg tgacatcatc tggcacctgc acctttagct
    34861 gtaaatcctt cttcttgagc tgaggttgca agctttgagt caaatcctgt acaaattctg
    34921 ccaaagaaag ggtcgtccat tgtataggca tttgttgagc cttagataag gtaagaagat
    34981 gctcaacaat atgctcaaga cgcaagcttt ctttgtaaat aatgtctaga aagtcatcct
    35041 tgagcgcttc ttcttcagct gacatcccct taatggtttc agcaaagccc ttaatcgaag
    35101 taactggtgt cctcaattca tgggaggcat ttgagacaaa ggctaaattt aacttttcat
    35161 aagttctaat cgttgttaaa tcatatagca agacgagcac agcttccaca gattgggtgg
    35221 ggctaaaaac gggaactgct gtcacttcta aaatcaagtc accctcatga aacccactta
    35281 cttcttgttt taaccttgtt ttttgatcaa aggcttggtg aactaaattt cgaatatcca
    35341 tccgtttgag gtcatcaagt gaacttatgt cgccgtccac atcgggaaaa taatgaggca
    35401 gagagcgact ggataataac atctgacctt gagcggaaac taaaaacgtc cccatggtta
    35461 ggtgcgacag aagaacctcc attgtttcgg ctaggtcctt gtattgctga tcctgttggg
    35521 agactttggt ttttagggca gacacatact gagccaaaga ctttaagtct tcttgccctt
    35581 tttctaaaaa gtattcacta ctggtcaaga gaggttggtg caaggtctca aaagcaactt
    35641 cccatttcca aaggcaaaag agccagtagc caccttgtcc caaagaaagg gctagaagaa
    35701 agagaccgat gcctttactg atccaagtta atgccatccc tgcaatcaga atgaggctaa
    35761 cacttagatt gactagccaa aattgaaggt agcgtttcat ctataactcc ttgaacttat
    35821 aaccataacc ccgaatggtt cgaataaatt gaggggcttt aggattgtct tcaatttttt
    35881 ccctcaactt accaatatga acgtccacca aacgtgtttc ctgcccaaag tcataccccc
    35941 agatacgttc caaaagacgc tctctagtca gtgtcatgtt gggatgtttc ataagataga
    36001 gcaagagttc aaattctttt ggggtcaaac tcagtaactt attcgccttg tagacttcat
    36061 gacgctcagg gtatactttc aaggtcccaa atagccaaga atcgtcagcg atattatctg
    36121 aatcatctcc ttcttgttct cctttagttc gcctgaggac agccttgaca cgcgccagca
    36181 attctctagg gctaaaaggc ttggtcaggt agtcatcagc ccctaattcc aaggccaaaa
    36241 ccttatcaaa ttcatcactt ttcgcagaaa ccatcataat tggagttttg acgcctttgg
    36301 ctctcagccg cttacaaact tccatgccat ctaattgtgg taacatgata tcaagcaaga
    36361 taaaatcaaa gggttctgtt tctgccaaag ctaaggcctt ccgtccattt gttaccaatt
    36421 gagtagaaaa gccttcctta cttaaatggt agtcaagcaa tttcagaatg tgttcttcat
    36481 catccactaa taagacttgt tttgtcatct attatctcct attggtaaca ttataacaca
    36541 attatcagaa atcctaacat tgctaaatca gattaaattt gcttatcaag actagtatct
    36601 ggtcaaacgc tcaatcatct ccttgtgctc tggataggtc gccagtagat ctaccctttc
    36661 aaataattca aaatcctcaa attcaaaacc aggagcaaca agacaagaaa ccagagcata
    36721 atccttatca actgttgatc cccaaatagt gcccttagga acacagtagt gaagttgttg
    36781 ccctttggat atgtccaggc ctaaagtgac tgcttcgtag tgaccatctg ctgtaatcat
    36841 gtgaacagta agtggggatc ctgcatgaaa ataccagatt tcatctgctg tcaatcggtg
    36901 aaaatgtgaa ggattcgttt cttctaataa gaaataaata ctggtataaa gcgcccttcc
    36961 cttaccagca aggtttatag tgtctgaagc tttttttgtt tgtctaaaat agccaccttc
    37021 aacatgggga gctaactcta gagttcttat caagtcttct ttatccgtcg gagccaatgg
    37081 gttgaagtaa ctcttgttca aaggtggtgt tacgatttca agaactcctc tcagctctga
    37141 ggacacgata atgattgatg cgacggaagt acaaatcaat cgccctaaaa aaagaattag
    37201 cgaattattc tggtaaaaaa atgcc
//
LOCUS       DAVBEO010000016        37119 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 009
            SAMEA1678075-rid20185393.denovo.016, whole genome shotgun sequence.
ACCESSION   DAVBEO010000016 DAVBEO010000000
VERSION     DAVBEO010000016.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678075
            Sequence Read Archive: ERR226392
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 37119)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 37119)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980207.1
            Genome Coverage       :: 150x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:50:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 72 of 147
            Pseudo Genes (incomplete)         :: 72 of 147
            Pseudo Genes (internal stop)      :: 42 of 147
            Pseudo Genes (multiple problems)  :: 32 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..37119
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678075-rid20185393.denovo.016"
                     /strain="KS 009"
                     /db_xref="taxon:1313"
     gene            238..576
                     /locus_tag="VQ543_000835"
     CDS             238..576
                     /locus_tag="VQ543_000835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000176371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antibiotic biosynthesis monooxygenase"
                     /protein_id="HET2611581.1"
                     /translation="MTLTIHVYYKGDGDCAIKFAREMLESGLVAEIRCQKGNLKYEYF
                     LPIEKEGIILLIDQWINQEALDEHHQSNTMQKILDLRKKYHLQMQVERYIEDDSGMPE
                     SDKSFIDTGN"
     gene            766..2202
                     /locus_tag="VQ543_000836"
     CDS             766..2202
                     /locus_tag="VQ543_000836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HET2611582.1"
                     /translation="MTTFKDGFLWGGAVAAHQLEGGWQEGGKGISVADVMTAGRHGVA
                     REITLGVLEGKYYPNHEAIDFYHRYKEDIALFAEMGFKCFRTSIAWTRIFPKGDELEP
                     NEEGLQFYDNLFDECLKNGIEPVITLSHFEMPYHLVTEYGGWKNRKLIDFFARFAEVV
                     FKRYKDKVKYWMTFNEINNQANYQEDFAPFTNSGIVYEEGDNREAIMYQAAHYELVAS
                     ARAVKIGHEINPDFQIGCMIAMCPIYPVTCNPKDILMAMKAMQKRYYFADVHVLGKYP
                     EHIFKYWERKGISVDFTDQDKEDLLGGTVDYIGFSYYMSFAIDSHRENNPYFDYLETE
                     DLVKNNYVKASEWEWQIDPEGLRYALNWFTDHYHLPLFIVENGFGAIDQVAADGMVHD
                     DYRIEYLGAHIREMKKAVVEDGVDLMGYTPWGCIDLVSAGTGEMRKRYGFIYVDKDDN
                     GKGSYNRSPKKSFGWYKKVILSNGESVE"
     gene            2254..2493
                     /locus_tag="VQ543_000837"
     CDS             2254..2493
                     /locus_tag="VQ543_000837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000580385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SemiSWEET family sugar transporter"
                     /protein_id="HET2611583.1"
                     /translation="MIGSIAAILTTFAFLPQVFRVVKTKDTGSIALGMYVMQVIGIAL
                     WLAHGIRIGDLPLILANSVSFLLSGIILFYKLKYK"
     gene            2623..2937
                     /locus_tag="VQ543_000838"
     CDS             2623..2937
                     /locus_tag="VQ543_000838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003037418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIB"
                     /protein_id="HET2611584.1"
                     /translation="MAKALIICAAGMSSSLMAQKTTEFLKGKGKDIVVDAISATEGGK
                     AIAAAAFDLYLVSPQTKMYFKQFEEAGSKAGKPVVQIPPQAYIPIPMGIEKMANLILE
                     NI"
     gene            3055..5034
                     /locus_tag="VQ543_000839"
     CDS             3055..5034
                     /locus_tag="VQ543_000839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001101767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HET2611585.1"
                     /translation="MNVLNIKEKDILQFLIKNKERFVTSKELAEYLSCSDRTVRNVLK
                     LIEKTMIIQGVRLISKQGQGYQIFFENQGAYQEFRQTYELEEDYTKTAVSKGDDRLVF
                     ILNKLLFEQVPVLFDDLADELYVSRSTLSHDFRKIRVMLSEYNLSIESRANKGVYVSG
                     EERDKRRFIINYFLENQFFKTIHCYVKFNFFAQTVPLEEFARIVLDECQEANLKLSDF
                     VLQNLVVHIALSVIRLKSGFEIKNIDCQMTDDAIERKVAQRILSKVREVTNQEFPVQE
                     IDYITLHLLAKSQQCQKNQKNISEEVLKKSLFKTFQNLGLDDMYNFSSDFQLIEGLIT
                     HLMTLQVRLESRITLNNPLVDEIKQNYSDIFFMTREILANMDKFLEWTISDDEVAYVS
                     LHFLAAMERSKESTKFNILAICATGFGAAQMLRNRLETEFGKRVEVVDVIGYYELNQE
                     KLKGIDFIVSAVDLSNLYFQIPVFKVSVFLKSDEMEMIRKAMDQMQVSSYVQSSKINK
                     FENNSFRQYFSKENFLICTESDKVNLLEKMVESLSVGESNEFEQSLLYGIKQREELSS
                     VVFSEKIAVPHPIQPFGTEGKVSVAICKDSLLWDNQSSYVQLVFLLSPSIYGNEGLAT
                     VTKKIVSLTENDELQNQLISCNNFEDFISIFEKIK"
     gene            5044..5358
                     /locus_tag="VQ543_000840"
     CDS             5044..5358
                     /locus_tag="VQ543_000840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001070943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIA"
                     /protein_id="HET2611586.1"
                     /translation="MNQEELQVAAFEIILHSGNARSEIHEAFAKMREGSFDDAESKLN
                     QSNEIILEAHHAQTKLLQEYASGVEIKIEIIMVHAQDHLMTTMTLLEVAKEMLALYKK
                     VN"
     gene            5389..5895
                     /locus_tag="VQ543_000841"
     CDS             5389..5895
                     /locus_tag="VQ543_000841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2611587.1"
                     /translation="MDKKERQKIEQQRREMALTNTFFNRYLLLRYSIALFFFGNIYWL
                     LNQFINPSPIIIFPIMLIVFSILATVEQFKLYGNRKEKLGITLMFVRIQILISIGLLV
                     LTWTSWFKNLFPIFENNQVARLFVFVVLLLGLVLSLLDIRRIKKIYKRTDKAYQQFVQ
                     LEKNSLSL"
     gene            5975..7321
                     /gene="celB"
                     /locus_tag="VQ543_000842"
     CDS             5975..7321
                     /gene="celB"
                     /locus_tag="VQ543_000842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIC"
                     /protein_id="HET2611588.1"
                     /translation="MDQQNGLFGFLENHVMGPMGKLAQFKVVRAITAAGMAAVPFTIV
                     GSMFLVFSILPQAFSFWPIVADIFSASFDKFTSLYMVANYATMGSLSLYFVLSLAYEL
                     TKIYAEEEELNMNPLNGALLALMAFVMTVPQIIFDGGMMKTVTSLKEGAVIADGWAMG
                     NGVARFGTTGIFTAIIMAIVTVLIYRMCVKHNWVIKMPEAVPEGVSRGFTALVPGFVV
                     AFVVIFINGLLVAMGTDIFKVIAIPFGFVSNLTNSWIGLMIIYLLTQLLWIVGIHGAN
                     IVFAFVSPIALANMAENAAGGHFAVAGEFSNMFVIAGGSGATLGLCLYIAFASKSEQL
                     KAIGRASVVPALFNINEPLIFGLPIIYNPALAIPFILAPMVTATIYYVANSLNFIKPI
                     IAQVPWPTPVGIGAFLGTADLRAVLVALVCAFAAFLVYLPFIRVYDQKLVKEEQGI"
     gene            7701..7877
                     /locus_tag="VQ543_000843"
     CDS             7701..7877
                     /locus_tag="VQ543_000843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2611589.1"
                     /translation="MSLDIDKEKMTIMGIAFENRSVFKSVWYALSTNMIEGWRPTVSD
                     VEKLRDEALALGMT"
     gene            8287..10500
                     /locus_tag="VQ543_000844"
     CDS             8287..10500
                     /locus_tag="VQ543_000844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000688702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-xylosidase"
                     /protein_id="HET2611590.1"
                     /translation="MKIFKGEFYRISVLTDKLVRLEYSQTGSFEDRTTQLIYNRDFGQ
                     VSLDYIETSNVLDIMTDYFHLHFNKGEFNAENLFIELKGNFAVYGSRWYFGESIETLK
                     GTARTLDKADGAISLEDGIISRNGIALLDDSQGFIWDEQSGYIERENQIDLYFFAYGH
                     DYRGAIRDFYHLTGSTPLLPRYALGNWWSRYWPYTSDEYLDLIDRFETEKIPLSIGVL
                     DMDWHITDIPARFGSGWTGYSWNRNLIPNPEQLLQQLHDRKLKLSLNVHPADGIRAYE
                     EAYPQIAKRLGLNVELEEPAIFDFFNPSFREAYFKDVHYELEKQGVDFWWIDWQQGTQ
                     GMLDPLWLLNHYHYQDSCKNAEGGLILSRYAGPGSHRYPVGFSGDTIISWNSLRFQPY
                     FTATASNIGYSWWSHDIGGHMLGDYDEELQTRWLQFGVFSPITRLHSSRSPFNSKEPW
                     FFSETTSKIMKKYLRLRHQMIPYLYTMNVKTHEEGAPLISPIYYFYPENDESYNVPNQ
                     YFFGTELMVAPIVEKMDLTFQSAKVDVWFPEGEWYDFFSEKKYTGGVKLSVYRDISTT
                     PVFAKSGAIIPLVGSEIGMGVDLPEVVDWYVFPGKQHFFEMLEDQNGQRYKTRLSIDW
                     EMGMVELALQGDSSIVPSNRKHRIHFKGTNVSIIELPNKNDTAKFEWKDNKRTSLNDE
                     VFRLLKTASLPYELKDRLLNQFINAKNSHDLMNILHHQDKELRGRLLEMIFTSQN"
     gene            complement(10722..11198)
                     /locus_tag="VQ543_000845"
     CDS             complement(10722..11198)
                     /locus_tag="VQ543_000845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione peroxidase"
                     /protein_id="HET2611591.1"
                     /translation="MTSLYDFSVLNQNNQATPLDSYRGKVLLIVNTATGCGLTPQYQG
                     LQELYERYQDQGFEILDFPCNQFMGQAPGSAEEINAFCSLHFQTTFPRFAKIKVNGKE
                     ADPLYVWLKDQKSGPLGKRIEWNFAKFLIGRDGQVFERFSSKTDPKQIEEAIQTLL"
     gene            11421..14621
                     /locus_tag="VQ543_000846"
     CDS             11421..14621
                     /locus_tag="VQ543_000846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001193686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored hyaluronate lyase"
                     /protein_id="HET2611592.1"
                     /translation="MQTKTKKLIVSLSSLVLSGFLLNHYMTVGAEETTTNTIQQSQKE
                     VQYQQRDTKNLVENGDFGQTEDGSSPWTGSKAQGWSAWVDQKNSADASTRVIEAKDGA
                     ITISSHEKLRAAVHRMVPIEAKKKYKLRFKIKTDHKVGIAKVRIIEESDKDKRLWNSA
                     TTSGTKDWQTIEADYSPTLDVDKIKLELFYETGTGTVSFKDIELVEVADQPSEDYQTD
                     KQLEEKIDLPIGKKHVFSLADYTYKVENPDVASVKNGILEPLKEGTTNVIVSKDGKEV
                     KKIPLKILASVKDAYTDRLDDWNGIIAGNQYYDSKNEQMAKLNQELEGKVADSLSSIS
                     SQADRTYLWEKFSNYKMSANLTATYRKLEEMAKQVTNPSSRYYQDETVVRTVRDSMEW
                     MHKHVYNSEKSIVGNWWDYEIGTPRAINNTLSLMKEYFSDEEIKKYTDVIEKFVPDPE
                     HFRKTTDNPFKALGGNLVDMGRVKVIAGLLRKDDQEISSTIRSIEQVFKLVDQGEGFY
                     QDGSYIDHTNVAYTGAYGNVLIDGLSQLLPVIQKTKNPIDKDKMQTMYHWIDKSFAPL
                     LVNGELMDMSRGRSISRANSEGHVAAVEVLRGIHRIADMSEGETKQRLQSLVKTIVQS
                     DSYYDVFKNLKTYKDISLMQSLLSDAGVASVPRTSYLSAFNKMDKTAMYNAEKGFGFG
                     LSLFSSRTLNYEHMNKENKRGWYTSDGMFYLYNGDLSHYSDGYWPTVNPYKMPGTTET
                     DAKRADSDTGKVLPSAFVGTSKLDDANATATMDFTNWNQTLTAHKSWFMLKDKIAFLG
                     SNIQNTSTDTAATTIDQRKLESSNPYKVYVNDKEASLTEQEKDYPETQSVFLESSDSK
                     KNIGYFFFKKSSISMSKALQKGAWKDINEGQSDKEVENEFLTISQAHKQNGDSYGYML
                     IPNVGRATFNQMIKELERSLIENNETLQSVYDAKQGVWGIVKYDDSVSTISNQFQVLK
                     RGVYTIRKEGDEYKIAYYNPETQESAPDQEVFKKLEQAAQPQVQNSKEKEKSEEEKNH
                     SDQKNLPQTGEGQSILASLGFLLLGAFYLFRRGKNN"
     gene            15001..15386
                     /gene="tnpA"
                     /locus_tag="VQ543_000847"
                     /pseudo
     CDS             15001..15386
                     /gene="tnpA"
                     /locus_tag="VQ543_000847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005816675.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
     gene            complement(15765..16394)
                     /locus_tag="VQ543_000848"
     CDS             complement(15765..16394)
                     /locus_tag="VQ543_000848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 4-hydroxy-2-oxoglutarate
                     aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase"
                     /protein_id="HET2611593.1"
                     /translation="MTKSDTIIELKKQKIVAVIRGNTKEEGLQASIACIKGGIKAIEI
                     AYTNQYAGQIIKELVDLYQDDQSVCIGAGTVLDAVTARDAILAGANYVVSPSFHAETA
                     KMCNLYSTPYIPGCITLTEITTALEAGSEIIKLFPGSTLSPAYISAVKAPIPQVSVMV
                     TGGVGLNNIPQWFAAGADAVGIGGELNKLASQGNFDRISEIAQQYITLR"
     gene            complement(16404..17405)
                     /locus_tag="VQ543_000849"
     CDS             complement(16404..17405)
                     /locus_tag="VQ543_000849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="HET2611594.1"
                     /translation="MTKILLFGEPLIRISPLDATSIGDHVASSTYFGGSEINIACNLQ
                     ALGISTKVFTALPANEIGDRFLTFLKQHQIDTSSICRLGDRIGLYYLENGFGCRQSEV
                     FYDRKHTSISQIRPNMLDMDSLFQGISHFHFSGITIAIGQEVRAILLLLLEEAKRRGI
                     VVSMDLNLRTKMISVLEAKYEFSKFARFTDYCFGIDPLMIDDQNLEMFPRDSASLEEV
                     ENRMRLLKEAYGFKAIFHTLRSSDEQDKNVYQAYALEERFEESVQLKTAVYQRIGSGD
                     AFISGALYQLLHHSSLKTTIDFAVASATLKCTLPGDHLSTSATSIENLLANAQDIIR"
     gene            complement(17436..18077)
                     /locus_tag="VQ543_000850"
     CDS             complement(17436..18077)
                     /locus_tag="VQ543_000850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RpiB/LacA/LacB family sugar-phosphate isomerase"
                     /protein_id="HET2611595.1"
                     /translation="MKIALINENSQASKNHIIYDSLKEATDKKDYQLFNYGMRGEEGE
                     SQLTYVQNGLMAAILLNTKAVDFVVTGCGTGVGAMLALNSFPGVVCGLAVDPTDAYLY
                     SQINGGNALSIPYAKGFGWGAELTLKLMFERLFAEEMGGGYPRERVIPEQRNARILNE
                     VKQITHNDLMTILKTIDQDFLKDTISGKYFQEYFFENCQDDEVAAYLKEVLAK"
     gene            complement(18096..18911)
                     /locus_tag="VQ543_000851"
     CDS             complement(18096..18911)
                     /locus_tag="VQ543_000851"
                     /EC_number="1.1.1.69"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000185867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconate 5-dehydrogenase"
                     /protein_id="HET2611596.1"
                     /translation="MTNTSFSIEQFSLKGKIALITGASYGIGFAIAKSYAEAGATIVF
                     NDINQDLVNKGIEAYREVGIEAHGYVCDVTDEDGIQAMVKQIEQEVGVIDILVNNAGI
                     IRRVPMCEMSAADFRKVIDIDLNAPFIVSKAVIPSMIKKGHGKIINICSMMSELGRET
                     VSAYAAAKGGLKMLTRNIASEYGGANIQCNGIGPGYIATPQTAPLRELQEDGSRHPFD
                     QFIIAKTPAARWGNPEDLMGPAVFLASDASNFVNGHILYVDGGILAYIGKQPE"
     gene            19182..19610
                     /locus_tag="VQ543_000852"
     CDS             19182..19610
                     /locus_tag="VQ543_000852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000706826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HET2611597.1"
                     /translation="MKIVLVGHGHFATGIYSSLQLIAGNQENVEAIDFVEGMSADELK
                     QKILLAISNEEEVLILSDLLGGSPFKVSSTIMGENPVKTMNVLSGLNLAMLMEAVFAR
                     MAHSFDEVVNKSVVAAQGGVVNGKELFSTDAEEEDFESGI"
     gene            19622..20812
                     /locus_tag="VQ543_000853"
     CDS             19622..20812
                     /locus_tag="VQ543_000853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003074342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HET2611598.1"
                     /translation="MIKKVTIEKIKSPERFLEVPLLTKEEVGQAIDKVIRQLELNLDY
                     FKEDFPTPATFDNVYPIMDNTEWTNGFWTGELWLAYEYSQQDAFKNIAHKNVLSFLDR
                     VNKRVELDHHDLGFLYTPSCMAEYKINGDGEAREATLKAADKLIERYQEKGGFIQAWG
                     DLGKKEHYRLIIDCLLNIQLLFFAYQETGDQKYYDIAESHFYASANNVIRDDASSFHT
                     FYFDPETGQPFKGVTRQGYSDDSCWARGQSWGVYGIPLTYRHLKDESCFDLFKGVTNY
                     FLNRLPKDHVSYWDLIFNDGSAQSRDSSATAIAVCGIHEMLKHLPEVDADKDIYKHAM
                     HAMLRSLIEHYANDQFTPGGTSLLHGVYSWHSGKGVDEGNIWGDYYYLEALIRFYKDW
                     NLYW"
     gene            20823..21314
                     /locus_tag="VQ543_000854"
     CDS             20823..21314
                     /locus_tag="VQ543_000854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000178618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system
                     mannose/fructose/N-acetylgalactosamine-transporter subunit
                     IIB"
                     /protein_id="HET2611599.1"
                     /translation="MTMPNIIMTRIDERLIHGQGQLWVKYLACNTVIVANDEVSTDKM
                     QQTLMKTVVPDSVAMRFFPLQKVIDIIHKANPAQTIFIVVKDVKDALTLVEGGVPIKE
                     INIGNIHNAPGKEQVTRSIFLGEEDKAALKELSQTHQVTFNTKTTPTGNDGAVQVNIM
                     DYI"
     gene            21329..22108
                     /locus_tag="VQ543_000855"
     CDS             21329..22108
                     /locus_tag="VQ543_000855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000026606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HET2611600.1"
                     /translation="MSINVFQAILIGLWTAFCFSGMLLGIYTNRCIVLSFGVGIILGD
                     LPTALAMGAIGELAYMGFGVGAGGTVPPNPIGPGIFGTLMAITSAGKVSPEAALALST
                     PIAVAIQFLQTFAYTVRAGAPETAMKHLKNHNLKKFKFTLNATIWLFAFIGFTLGCLG
                     ALSMDTLLKLVDYIPPVLLTGLTVAGKMLPAIGFAMILSVMAKKELIPFVLLGYVCAA
                     YLNIPTIGIAIVGTIFALIEFYNKPKTANHVVEEEAHDDWI"
     gene            22095..22913
                     /locus_tag="VQ543_000856"
     CDS             22095..22913
                     /locus_tag="VQ543_000856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000148012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HET2611601.1"
                     /translation="MTGSNKLTKRDYLKTSLRAFFCQNGFNYSNYQGLGYANVMYPAL
                     KKHYGEDQEGFYQALEENCEFYNTNPHFLPFITSLHLVMLENGRPAKETRSIKMALMG
                     PLAGIGDSLSQFCLAPLFSTIAASFAQEGLVVGPILFFLAMNTILTAIKLSTGLYGYK
                     LGTTVIDKLSEQMATISRIANIIGVTVIAGLAATSVKIMVPITFAAGEVKADAKQSIV
                     SIQGMLDKVAPALLPALFTLLVYYLIKEKKWTTYKLVILTVVIGIIGSWLKIIA"
     gene            22913..23206
                     /locus_tag="VQ543_000857"
     CDS             22913..23206
                     /locus_tag="VQ543_000857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000381741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HET2611602.1"
                     /translation="MDTTLFYGIVIVLAVSPLLLSSFHSIRQQKLLRKQTEQRQEYLA
                     SLTSGDEVLLLSGIHGKIISIKDDLVSLQIAKGVVIYVEKESVMGKTKELLFK"
     gene            23228..25129
                     /locus_tag="VQ543_000858"
     CDS             23228..25129
                     /locus_tag="VQ543_000858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000657070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alginate lyase family protein"
                     /protein_id="HET2611603.1"
                     /translation="MKEERRQFFERVDGNQCRDYILSHCSKDYEKVKSSLERLMDNRF
                     MFDSPWDMEPCSKIHQIQPMVWDQVFEDDPEWAYMLNRQEYLLQFMIGYVVEGDKDYI
                     QKCKFFLFDWIEQVREFSPQSLMTRTLDTGIRSFTWLKLLLLLLKFDMLEEKELEKIL
                     VSLEKQIDFMKSYYRAKYTLSNWGILQTIPMLAIYYFFSDKMDLEEAYHFASEELKQQ
                     IETQILGDGSQFEQSILYHVEVYKALLDLCLLLPDLQDSYRELLEKMATYIQMMTGLD
                     GRTLAFGDSDSTETTEILSLSAVVLNKEDLLNGLDVKVDLLSLLFLGREKVKRLQEFE
                     KRAWQPKSMIFEDSGHVCIKDEHRYLFFKNGPLGSAHSHSDENSFCLQYQGQPIFIDA
                     GRYSYREIYERYLLKSAWSHSTCIVDGKAPERITGSWEYEYYPHSLFCHHKEREGVHY
                     IEGAYWSAEPDLPYLHKRKILMLVEDVWLLVDDIRCQGQHEALTQFILDKDVTYQDGK
                     INQLRLWSEVDFDLEDTIISPKYNELERSNKLTKRQFFENQMLDYTIIAHESFEIIRH
                     SVYQTDDREVENALAFEVKNDETDKLILLLSEDICVGEKLCLVDGTKMRGKCLVYDKI
                     NERMIRLQC"
     gene            25189..26190
                     /locus_tag="VQ543_000859"
     CDS             25189..26190
                     /locus_tag="VQ543_000859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000412458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HET2611604.1"
                     /translation="MEKKLTIKDIAEMAQTSKTTVSFYLNGKYEKMSQETREKIEKVI
                     HETNYKPSIVARSLNSKRTKLIGVLIGDITNSFSNQIVKGIEDIASQNGYQVMIGNSN
                     YSQESEDRYIESMLLLGVDGFIIQPTSNFRKYSRIIDEKKKKMVFFDSQLYEHRTSWV
                     KTNNYDAVYDMTQSCIEKGYEHFLLITADTSRLSTRIERASGFVDALTDANMRHASLT
                     IEDKHTNLEQIKEFLQKEIDPDEKTLVFIPNCWALPLVFTVIKELNYNLPQVGLIGFD
                     NTEWTCFSSPSVSTLVQPSFEEGQQATKILIDQIEGRNQEERQQVLDCSVNWKESTF"
     gene            complement(26300..26635)
                     /locus_tag="VQ543_000860"
     CDS             complement(26300..26635)
                     /locus_tag="VQ543_000860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000838135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2611605.1"
                     /translation="MKSLARLLNIHVFISIFLFFALISGAVSHTVLLLLLLFLPALNK
                     GLEKIQSKRIPVLNAALFFLLISFPQLLTNPVQWKFSIFLVVTIISSLAYFYNFYQVV
                     KEVDQKQLI"
     gene            complement(26646..26888)
                     /locus_tag="VQ543_000861"
     CDS             complement(26646..26888)
                     /locus_tag="VQ543_000861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2611606.1"
                     /translation="MKKEKKQLRYPGLKAGSIYGTVIFFIIPLIDTLTSENPNFISSL
                     LNTKHIFKTILGAFFFGVMIHIVDSLRIARAKKDQD"
     gene            complement(26899..27441)
                     /locus_tag="VQ543_000862"
     CDS             complement(26899..27441)
                     /locus_tag="VQ543_000862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000712356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3278 domain-containing protein"
                     /protein_id="HET2611607.1"
                     /translation="MKKETFTEKLIKRTYGISGPLDEYKRREADSIGNQVFIVLFYLM
                     IFGNLIPLLLAYKYPQEVALIYPPLILVIALIAAGYVTYQMKKTGITVIEPDMLNEKE
                     SKQLHYPGLKAGLFFGLWMFFITPLLSILIDEGQDYFHSLLTIRNGVSSILGSIFFGA
                     SIQFLISRRIAKTKKNQDED"
     gene            complement(27457..27651)
                     /locus_tag="VQ543_000863"
     CDS             complement(27457..27651)
                     /locus_tag="VQ543_000863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001082472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET2611608.1"
                     /translation="MNRVKEFRKELGISQLELAKDIGVSRQTINMIENDKYNPTLELC
                     LNLARSLQTDLNSLFWEEDF"
     gene            27817..28767
                     /gene="rsmH"
                     /locus_tag="VQ543_000864"
     CDS             27817..28767
                     /gene="rsmH"
                     /locus_tag="VQ543_000864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(1402)-N(4))-methyltransferase
                     RsmH"
                     /protein_id="HET2611609.1"
                     /translation="MTKEFHHVTVLLHETIDMLDVKPDGIYVDATLGGAGHSEYLLSK
                     LSEKGHLYAFDQDQNAIDNAQKRLAPYIEKGMVTFIKDNFRHLQARLREAGVQEIDGI
                     CYDLGVSSPQLDQRERGFSYKKDAPLDMRMNQDASLTAYEVVNHYDYHDLVRIFFKYG
                     EDKFSKQIARKIEQAREVKPIETTTELAEIIKLVKPAKELKKKGHPAKQIFQAIRIEV
                     NDELGAADESIQQAMDMLALDGRISVITFHSLEDRLTKQLFKEASTVEVPKGLPFIPD
                     DLKPKMELVSRKPILPSAEELEANNRSHSAKLRVARKIHK"
     gene            28779..29096
                     /gene="ftsL"
                     /locus_tag="VQ543_000865"
     CDS             28779..29096
                     /gene="ftsL"
                     /locus_tag="VQ543_000865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsL"
                     /protein_id="HET2611610.1"
                     /translation="MAEKMEKTGQILQMQLKRFSRVEKAFYFSIAVTTLIVAISIIFM
                     QTKLLQVQNDLTKINAQIEEKKTELDDAKQEVNELLRAERLKEIANSHDLQLNNENIR
                     IAE"
     gene            29100..31352
                     /gene="pbpX"
                     /locus_tag="VQ543_000866"
     CDS             29100..31352
                     /gene="pbpX"
                     /locus_tag="VQ543_000866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000872287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2X"
                     /protein_id="HET2611611.1"
                     /translation="MKWTKRVIRYATKNRKSPAENRRRVGKSLSLLSVFVFAIFLVNF
                     AVIIGTGTRFGTDLAKEAKKVHQTTRTVPAKRGTIYDRNGVPIAEDATSYNVYAVIDE
                     NYKSATGKILYVEKTQFNKVAEVFHKYLDMEESYVREQLSQPNLKQVSFGAKGNGITY
                     ANMMSIKKELEAAEVKGIDFTTSPNRSYPNGQFASSFIGLAQLHENEDGSKSLLGTSG
                     MESSLNSILAGTDGIITYEKDRLGNIVPGTEQVSQRTMDGKDVYTTISSPLQSFMETQ
                     MDSFQEKVKGKYMTATLVSAKTGEILATTQRPTFDADTKEGITEDFVWRDILYQSNYE
                     PGSTMKVMMLAAAIDNNTFPGGEVFNSSELKIADATIRDWDVNEGLTGGRMMTFSQGF
                     AHSSNVGMTLLEQKMGDATWLDYLNRFKFGVPTRFGLTDEYAGQLPADNIVNIAQSSF
                     GQGISVTQTQMIRAFTAIANDGVMLEPKFISAVYDPNDQTARKSQKEIVGNPVSKDAA
                     SLTRTNMVLVGTDPVYGTMYNHSTGKPTVTVPGQNVALKSGTAQIADEKNGGYLVGLT
                     DYIFSAVSMSPAENPDFILYVTVQQPEHYSGIQLGEFANPILERASAMKDSLNLQTTA
                     KALEQVSQQSPYPMPSVKDISPGDLAEELRRNLVQPIVVGTGTKIKNSSAEEGKNLAP
                     NQQVLILSDKVEEVPDMYGWTKETAETLAKWLNIELEFQGSGSTVQKQDVRANTAIKD
                     IKKITLTLGD"
     gene            31354..32334
                     /locus_tag="VQ543_000867"
     CDS             31354..32334
                     /locus_tag="VQ543_000867"
                     /EC_number="2.7.8.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000470804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-N-acetylmuramoyl-pentapeptide-
                     transferase"
                     /protein_id="HET2611612.1"
                     /translation="MFISISAGIVTFLLTLVGIPAFIQFYRKAQITGQQMHEDVKQHQ
                     AKAGTPTMGGLVFLITSVLVAFFFALFSSQFSNNMGMILFILVLYGLVGFLDDFLKVF
                     RKINEGLNPKQKLALQLLGGVIFYLFYERGGDMLSVFGYQVHLGIFYIVFALFWLVGF
                     SNAVNLTDGVDGLASISVVISLSAYGVIAYVQGQMDILLVILAMIGGLLSFFIFNHKP
                     AKVFMGDVGSLALGGMLAAISMALHQEWTLLIIGIVYVFETTSVMMQVSYFKLTGGKR
                     IFRMTPVHHHFELGGLSGKGNPWSEWKVDFFFWGVGLLASLLTLAILYLM"
     gene            32943..35048
                     /locus_tag="VQ543_000868"
     CDS             32943..35048
                     /locus_tag="VQ543_000868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001063457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HET2611613.1"
                     /translation="MNNNFNNFNNMDDLFNQLMGGMRGYSSENRRYLINGREVTPEEF
                     AHYRATGQLPGNAETDVQMPQQASGMKQDGVLAKLGRNLTAEAREGKLDPVIGRNKEI
                     QETSEILSRRTKNNPVLVGDAGVGKTAVVEGLAQAIVNGDVPAAIKNKEIISIDISGL
                     EAGTQYRGSFEENVQNLVNEVKEAGNIILFFDEIHQILGAGSTGGDSGSKGLADILKP
                     ALSRGELTVIGATTQDEYRNTILKNAALARRFNEVKVNAPSAENTFKILQGIRDLYQQ
                     HHNVILPDEVLKAAVDYSVQYIPQRSLPDKAIDLVDVTAAHLAAQHPVTDVHAVEREI
                     ETEKDKQEKAVEAEDFEAALNYKTRIAELERKIENHTEDMKVTASVNDVAESVERMTG
                     IPVSQMGASDIERLKDMAHRLQEKVIGQDKAVEVVARAIRRNRAGFDEGNRPIGSFLF
                     VGSTGVGKTELAKQLALDMFGTQDAIIRLDMSEYSDRTAVSKLIGTTAGYVGYDDNSN
                     TLTERVRRNPYSIILLDEIEKADPQVITLLLQVLDDGRLTDGQGNTVNFKNTVVIATS
                     NAGFGYEANLTEDADKPELMDRLKPFFRPEFLNRFNAVIEFSHLTKEDLSKIVDLMLA
                     EVNQTLAKKDIDLVVSQAAKDYITEEGYDEVMGVRPLRRVVEQEIRDKVTDFHLDHLD
                     AKHLEADMEDGVLVIREKA"
     gene            35771..36790
                     /locus_tag="VQ543_000869"
     CDS             35771..36790
                     /locus_tag="VQ543_000869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic biosynthesis protein"
                     /protein_id="HET2611614.1"
                     /translation="MSNTLKQLLLFREEFIKNILNGIDVDETVVIENDFVEELENFLK
                     ENDLLDFSNSIFFQLSGDKVIVNNIYPGYLAYFNRFLTFYPKIFAIKEVGEYIDFLNF
                     EKRIADMFYCWGFNANSRVLTAEKIIEIPNHQINAKYIKKVIKMSELLFGVDSNNRIR
                     LLNNRRELIKTIFQGSVIKSAIPALAATLDTISNSGSFQISLSKQIINNLVLSGKDKV
                     TIPRIELDNVVLSRQKIIVSVSYINDFLDLRFPDKIEYILNFLEGSGFNTKVMVYFGK
                     IVEEDKNYFVNLEKPQYFDFTSILFNKLFFKELNKFDYMVIEELIPNLDEDVMMTEYI
                     KEYTE"
     gene            36803..>37119
                     /locus_tag="VQ543_000870"
     CDS             36803..>37119
                     /locus_tag="VQ543_000870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000603792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2611615.1"
                     /translation="MILSKVRCYIYNSKIRGKVLYELYEFINENKQLMDAINSIKVDS
                     SNGFSIQILHLGEQQTTVLLTDFFTKTLDLFKEFRVTNKSTLEQVKNQISILNSSGPK
                     MDLT"
BASE COUNT        11815 a         6040 c         7944 g        11320 t
ORIGIN      
        1 tatcaaaaag cacctcaaaa aggtattacc aagttgcaat accttttatg aggctctttt
       61 gtcttgttct tgtttcaatt gactataaat cgctataaga aaaaatcatt ttattggtat
      121 aaagaagtga ttgaaagtaa tggcgaaacg ttagataatt agttcataaa aaacaagttt
      181 agatcctcat ctaaacttgt ttttttaaaa ttgaaggatg attttggagg atatgagatg
      241 acattgacta ttcatgtata ttataaaggc gatggagatt gtgcaataaa gtttgcaaga
      301 gaaatgcttg aatctgggct tgtcgcagaa attagatgtc aaaaaggtaa tttgaaatac
      361 gaatattttt taccaattga aaaagaggga attattctcc ttattgatca gtggataaat
      421 caagaagctt tagatgaaca tcatcaatca aatacaatgc agaaaatctt agatttaaga
      481 aaaaaatatc acttgcagat gcaagttgaa cgttatatag aagatgattc tgggatgcca
      541 gaaagcgata agtcgtttat agacacaggg aattagaatt attgtgagag tttttgtagt
      601 ttgaaagtat tgaaaatcgt aaagatatca ttacgagaat acaagaagat attgttctat
      661 ttccattaaa aattacttct ttccttaata ataaggaaaa agaatacgtt ttcatctttt
      721 ggtttgaggt ttataataag aatatcaaag tcaggaggaa aaaagatgac tacttttaaa
      781 gatggatttt tatggggtgg tgctgttgct gctcatcaac ttgaaggcgg atggcaagaa
      841 ggtggcaaag gaattagtgt tgctgatgtt atgactgctg gtcgccatgg agtagctcgt
      901 gaaattactt tgggagtttt agagggtaaa tattatccaa atcatgaggc gatagatttt
      961 tatcatcgtt ataaagaaga catagcactt tttgctgaaa tgggattcaa gtgcttccgt
     1021 acctctattg catggacacg tatctttcca aaaggtgatg agttagagcc gaatgaagaa
     1081 ggattacagt tttatgataa tctttttgat gaatgcttaa agaatggtat tgaacctgtc
     1141 atcactctat ctcattttga aatgccttat cacttagtga ccgaatatgg tggttggaaa
     1201 aataggaaat tgattgattt ctttgctcgt tttgcagaag tcgtatttaa acgttacaaa
     1261 gataaggtta aatattggat gactttcaat gaaatcaata atcaagcgaa ttatcaggaa
     1321 gattttgcac catttactaa ctcaggtatt gtatatgagg aaggtgataa tagagaagca
     1381 attatgtatc aagcagcaca ttacgaatta gttgcttctg cacgagctgt aaaaattggt
     1441 catgagatta atccagattt tcaaataggt tgtatgattg cgatgtgtcc aatttatcca
     1501 gttacttgca atcctaagga tatcttaatg gcaatgaaag ctatgcagaa gcgttattat
     1561 tttgctgatg tgcatgtttt aggtaaatat cctgagcata ttttcaagta ttgggaacga
     1621 aaaggtattt cagttgattt tactgaccag gataaagaag atttacttgg tgggactgta
     1681 gattacattg gtttcagtta ctatatgtcc tttgctatag actctcatcg tgaaaataat
     1741 ccttattttg attatcttga aacagaagat ttagtgaaaa ataattatgt taaggcttct
     1801 gaatgggagt ggcaaattga tccagaaggt ttacgttatg cgttaaattg gtttacagac
     1861 cactatcact taccactctt tattgttgaa aatggttttg gagctataga tcaagttgca
     1921 gcagatggta tggtacatga tgattataga attgaatatc taggtgccca tattcgtgaa
     1981 atgaaaaagg ctgtagttga agatggtgtt gatttaatgg gttatactcc atggggatgt
     2041 attgatttgg tttcagctgg taccggtgaa atgcggaaac gttatggctt tatttatgta
     2101 gataaagatg acaatgggaa gggaagttat aatcgttccc cgaaaaaatc ttttggctgg
     2161 tataagaaag ttattttatc taacggtgaa tcagtagaat agtataaaca aactgagatt
     2221 attctcagtt tgtttagcat attgaggaga catatgattg gaagtattgc agcaatttta
     2281 acaacatttg catttttacc acaagttttt cgtgtagtta agacaaagga cacaggatct
     2341 attgctctag gtatgtatgt tatgcaagtt attggtattg cattgtggct tgctcatggt
     2401 attcgtatag gagacttgcc tttgatttta gcaaatagtg tttcatttct actctcagga
     2461 ataattttat tttataaatt gaagtataaa taattttttt ccatatcatt taggaaaatg
     2521 agggaattgt cattgaaaac gctttatttt ataataaaaa tagataacaa ataagccaac
     2581 ttagcacagc tttgattgga tttaagaaaa ggagaaaata ttatggcaaa agctttaatt
     2641 atttgtgcag caggaatgtc ttcatcactt atggcacaga aaacaacaga gtttctaaaa
     2701 ggaaaaggga aagatattgt agttgatgct attagtgcta ctgaaggagg gaaagctatc
     2761 gcagcagcag cttttgattt gtatcttgtc agtcctcaaa caaaaatgta ctttaagcaa
     2821 tttgaagagg ctggttctaa agcaggaaaa ccagttgtac aaatacctcc tcaagcctat
     2881 attcctattc caatgggaat tgaaaaaatg gctaatttga ttcttgagaa tatttgatga
     2941 acacatgaaa tgtcaataaa tatttaagtt aagataaatt gttttgagtt tgatataaat
     3001 tgatttaagt gtataatatg cttcaatata tgaaaacata cgttttagga gggaatgaat
     3061 gtgttaaaca ttaaagagaa agatatcctt caatttttaa taaaaaataa ggaacgtttt
     3121 gttacaagca aagaactggc agaatattta tcctgttcag atagaactgt ccgtaatgta
     3181 ctgaaattaa ttgagaagac aatgattatt caaggagtcc ggttgatttc aaaacaaggt
     3241 caagggtatc aaatattttt tgagaatcaa ggcgcttacc aggagtttag acaaacttat
     3301 gaactggaag aagactatac gaaaactgcg gtttcaaaag gtgatgatcg tttagtattt
     3361 atcttaaata aattattatt tgagcaagtt ccagttcttt ttgatgattt agctgatgaa
     3421 ctttacgtta gtcgttcaac attatctcat gatttcagaa agatacgagt gatgttatca
     3481 gagtataatt tgtccattga gagtagggcg aataaaggag tttatgtctc aggcgaggaa
     3541 cgtgataaac gacgttttat cataaattat ttcctagaga atcaattttt taaaacaata
     3601 cattgctatg taaaatttaa cttttttgct caaactgttc cattagaaga atttgctaga
     3661 attgttttgg atgaatgcca agaggccaac ctaaaactat ctgattttgt actacagaat
     3721 ttagtagttc acatagcatt gtctgtgatt cgtttaaaat ccggatttga aataaaaaat
     3781 atagactgtc agatgactga tgatgcaata gagagaaagg ttgctcaaag aattctttct
     3841 aaagtaagag aagtaacaaa tcaggaattt ccagttcagg aaatagacta cattactttg
     3901 catttgttag ctaagagtca acaatgtcaa aaaaatcaga agaatatttc tgaagaagtt
     3961 ttaaaaaaat ctttatttaa aacatttcag aatttaggat tagatgatat gtataacttt
     4021 tcttcagatt tccaactaat tgaaggattg ataactcatc taatgacact acaagtacgt
     4081 ttagaaagcc ggattacctt aaataaccct ttggtagatg aaattaaaca gaattatagt
     4141 gatatattct ttatgactag agaaattctt gcaaatatgg acaagttctt ggagtggaca
     4201 atatcagatg atgaagtagc atatgtaagt cttcactttt tagctgctat ggaacgtagc
     4261 aaagagagta ctaagtttaa tattcttgct atttgtgcaa caggatttgg tgcagcccaa
     4321 atgttaagaa atcgtttgga aacggagttt gggaagcgag tagaagttgt tgatgtaata
     4381 ggctattatg aattgaatca agaaaaactt aaaggaatag attttatagt gtcagctgtt
     4441 gatttatcaa atctatattt tcaaattcca gtttttaaag ttagtgtgtt tcttaagagt
     4501 gatgagatgg aaatgattag aaaagctatg gatcagatgc aagtttctag ttatgtacaa
     4561 tcatcaaaga ttaataaatt tgaaaacaac agctttagac agtattttag taaagaaaat
     4621 tttttaatat gtactgaatc agacaaggta aatttacttg aaaagatggt tgagagttta
     4681 tctgttggtg aatcaaatga gtttgaacaa tctttacttt atggaattaa acagcgcgaa
     4741 gaattaagtt cagttgtttt ttctgaaaaa attgcagttc cgcatcctat tcagcccttt
     4801 ggtacagagg gaaaggtttc ggttgcaatc tgtaaagatt cgttactctg ggataatcaa
     4861 agttcatatg tccagctagt atttcttcta tctccatcaa tatatgggaa cgaaggtttg
     4921 gcaactgtga ctaaaaagat agtctctctg acagagaatg atgagttgca aaatcagcta
     4981 atatcttgca ataactttga agattttatt agcatatttg agaagataaa ataggaggtt
     5041 catatgaatc aagaggaact gcaggttgca gcatttgaaa ttatcctgca ttcgggaaat
     5101 gcaaggtcag aaatacatga agcatttgca aaaatgagag aaggtagttt tgatgatgca
     5161 gaaagtaaat taaatcaatc aaatgagata attcttgaag cgcatcatgc acaaaccaaa
     5221 ctcttgcaag aatacgcaag tggagtggaa attaaaattg aaattatcat ggtacatgct
     5281 caagatcatt taatgaccac tatgacatta ttagaagtag caaaggaaat gttagctctt
     5341 tataagaaag ttaactaaat atgtgttgtt atataaggag gaaatgatat ggataaaaaa
     5401 gaacgacaaa agattgaaca acaacgtcga gagatggctc taactaatac tttttttaat
     5461 cgatatcttc ttctacgtta ttcaatagca ctcttctttt ttgggaatat ttattggctt
     5521 ttgaatcagt ttattaatcc ctcgcctatt attattttcc ccattatgct catagtattt
     5581 tctattttag caactgttga acaatttaaa ctctatggaa ataggaaaga aaagttggga
     5641 ataacactaa tgtttgttag aatacaaata cttatttcaa taggattact tgttttaact
     5701 tggacaagtt ggtttaagaa tctttttccg atttttgaaa ataaccaagt agcacgttta
     5761 tttgtttttg tagttcttct attaggttta gttctgagtt tgttagacat tagaagaatt
     5821 aaaaaaattt ataaacgaac agataaggct tatcaacaat ttgtccaatt ggaaaagaac
     5881 tcacttagtt tataatcctg atctagtata atttgtattt gaaactagtc tttagaaagt
     5941 aaaaattatt atgttttatt aaggaggtct atttatggat caacaaaacg ggttgtttgg
     6001 ttttcttgaa aaccatgtta tgggaccaat gggcaaactt gctcagttta aagtagtgcg
     6061 tgctatcacg gctgcaggta tggctgctgt accatttact attgtaggat caatgttttt
     6121 ggtattcagt attttgccac aagctttctc attttggcca attgtggcag atattttctc
     6181 tgcttcattt gataaattca catcacttta catggttgca aactatgcga ctatgggttc
     6241 tctatctctt tatttcgttc tatcacttgc atatgaattg acaaaaattt atgcagagga
     6301 agaagaactc aatatgaatc ctcttaatgg tgccttgctc gccttgatgg cttttgtcat
     6361 gacagtaccg caaatcattt ttgatggtgg aatgatgaag actgtgacaa gtctaaaaga
     6421 aggtgcagta attgcagatg gatgggcaat gggaaatgga gtcgcacgtt ttgggacaac
     6481 agggattttt accgcaatca ttatggcaat tgtgactgtt cttatttatc gtatgtgtgt
     6541 taaacataat tgggttatta aaatgcctga agctgttcca gaaggagttt ctcgtggatt
     6601 taccgctttg gttccgggat ttgttgttgc atttgttgtt atctttatca acggtcttct
     6661 tgtagcaatg ggaacagata tttttaaagt cattgcaatt ccatttggtt ttgtatccaa
     6721 tctgactaat tcgtggattg gtttaatgat tatttatcta ttgactcaac tactttggat
     6781 tgtaggtatc cacggtgcga acattgtttt tgcatttgtt agtccaattg ctcttgctaa
     6841 catggctgaa aatgctgctg gcgggcactt cgctgttgca ggtgaatttt ctaatatgtt
     6901 tgtaattgca ggtggttctg gtgcaacttt aggactatgt ttatatattg cttttgcctc
     6961 taaatctgaa cagcttaaag caataggacg agcatctgta gttccagcct tatttaatat
     7021 taatgaacca ttaatttttg gattacctat tatctataat ccagccttgg ctataccatt
     7081 tattttagca ccaatggtta ctgctactat ttattacgta gcgaattctc taaactttat
     7141 taagccaatt atcgcacagg ttccatggcc aactccagta gggattggag ctttcttagg
     7201 gacagcagat cttcgagctg tattagttgc tctagtatgt gcatttgcag cattcttagt
     7261 ctatcttcca ttcatccgtg tatatgatca aaaattggtg aaagaagagc aaggtatcta
     7321 ataagtaaaa aagtatactc gatgatagaa tccatatagt ttaaataatg agtgttaata
     7381 ttagcagtga agaggtcttt ttaagatatt cttctctgct ttttcatatt ttttcgctat
     7441 gtagggtatg aagcaaaata gaaagtagtt cgaatagttg ataaacagga aactgctgtt
     7501 atttaaaaaa aacaataaag taaagtatgt tatcgtagaa tacgatacaa tagtaaaaaa
     7561 gcaaaaagaa tgcgttttat atttgggttt gaggtttata aaataggata agcgtgctga
     7621 aaacttagat atgacaaaca aaataaaatt tttaaaagct acatagaaac atggtataat
     7681 gtatctaaag gaggtagcat atgtccttag atatagataa agaaaagatg acaatcatgg
     7741 gaatagcttt tgaaaacaga tccgttttta agagtgtttg gtatgcttta agtacaaata
     7801 tgattgaagg atggcgacct acggttagtg atgttgaaaa attacgagat gaagctcttg
     7861 ctctggggat gacttaatga agcgcaactg ttatgagtct tatgactatg ttgatccgga
     7921 taatttatat accgatccgg gttcttcagt tctaagaaat aagcaggaag gaaaaaagca
     7981 cgcgagcttg aatatcgtat gattgctagt aagagtttga aattatttat caatcctatc
     8041 ttagttaata gtttaaaagt agtttgtttc acaactgcat aagcttagaa aagttgaaaa
     8101 gtgataactc tttaataaac tcttggtttg ttaaaagata ttttgtccac tacatttttt
     8161 caattgacta ttatttgtca tagatataac agatagaaca gatagaacat tgcattcaga
     8221 ataatgaaaa acgcatcaaa aatggtgcgt tctgttttta tgctaccata aaaggaggaa
     8281 aacaaattga aaatttttaa gggagagttt tatcgaatct ctgtattaac agacaagcta
     8341 gtaaggttag aatactctca aactggaagt tttgaggata gaacgacaca acttatctat
     8401 aatagagatt ttggccaagt ttcgttagat tatatcgaga catcaaacgt actagatatt
     8461 atgacggact attttcatct gcactttaat aaaggagaat ttaacgccga aaatttattt
     8521 atagaattaa aaggaaattt tgccgtatat ggtagtcgct ggtattttgg tgaatctatt
     8581 gaaacgttaa aaggaacagc tcggactctg gataaggcag atggagcaat ctcgttagaa
     8641 gatggaatta ttagccgaaa tggtatagcc ttattggatg attctcaagg atttatttgg
     8701 gatgaacaat ctggttatat tgagagagaa aatcaaattg acctgtattt ctttgcctat
     8761 gggcatgatt atagaggagc aatcagagac ttttaccatt tgactggttc aacacccttg
     8821 ttgccaagat atgctttagg caattggtgg agtagatatt ggccttatac gtcggatgaa
     8881 tacttggatt taatagacag atttgaaaca gagaaaattc cattatctat cggtgtgtta
     8941 gatatggatt ggcatataac tgacattcca gctcgttttg gaagtggctg gacaggatat
     9001 agttggaata gaaacttaat accaaatcca gaacagttat tgcaacaact tcatgataga
     9061 aagttaaaac tctccttaaa tgtccatcct gctgatggga tacgggctta tgaagaagct
     9121 tatcctcaaa tcgcaaaacg gttggggtta aatgtagaac tagaagaacc tgctattttt
     9181 gattttttta atccctcttt tagggaagcc tactttaaag atgttcatta tgagctagaa
     9241 aagcagggag tagatttttg gtggattgac tggcaacaag ggacacaagg tatgctagat
     9301 ccactttggc ttttaaacca ttatcactat caggatagtt gtaaaaatgc agaaggtggt
     9361 ttgattttat caagatatgc aggtcctggt agtcaccgct accctgttgg tttttcaggg
     9421 gatactatta ttagttggaa ttccttaagg tttcaaccct attttacagc gacagcatct
     9481 aatatcggtt atagttggtg gagtcatgat atcggtggac atatgttggg ggattatgac
     9541 gaagagctac aaactagatg gctacagttt ggtgttttta gtccgattac tcgattacat
     9601 agttctagaa gtccttttaa tagtaaagaa ccttggttct tttcagaaac aacatctaag
     9661 attatgaaga aataccttcg tttgagacat cagatgattc cctatctata taccatgaat
     9721 gtaaagacac atgaggaagg tgccccatta atcagtccaa tctattattt ctatccagag
     9781 aatgatgaga gctataatgt tccaaaccaa tacttttttg gaacagaact gatggtggct
     9841 cccattgtag aaaagatgga tttgacattc caatctgcaa aagtagatgt atggttccct
     9901 gaaggtgaat ggtatgactt cttttcagag aaaaaataca caggtggtgt gaagttaagt
     9961 gtttataggg acatctcgac tacgcctgtg tttgcaaaaa gtggtgcaat cattcccttg
    10021 gttggttctg agataggtat gggtgttgat ttacctgagg ttgtagattg gtatgtattc
    10081 ccagggaaac aacatttttt tgaaatgctt gaagatcaaa atggtcaaag atataaaaca
    10141 agattatcaa tcgattggga aatgggaatg gtagagttag cattacaagg agattctagt
    10201 atcgttccaa gcaatagaaa acatagaatt cattttaaag gaacgaatgt gtctataatt
    10261 gaattgccaa ataagaatga tacagctaaa tttgaatgga aagataataa aaggacatct
    10321 ttaaatgacg aagtttttag actactaaag acagcttctc ttccatatga attaaaagat
    10381 agattgttaa atcaattcat caatgcgaaa aactctcatg acttaatgaa tatcttgcat
    10441 catcaggata aggaattgag agggcgtttg ttggaaatga tatttactag ccaaaactaa
    10501 ttgaaataat tagaaagtca tttgtttagt gtatatgaag attctgtatg gtattcgtta
    10561 tcactggtca cattgaaaat gtgaaataag cacctacaac atagacttta caacacttca
    10621 tgtttcatat catggggtgt ttttctattt aagtcaaagc ccatcaaaaa atctcactat
    10681 tcatcaggtt aaaggaaacc taatcatagt gagattgtga attatagtag agtttgtatc
    10741 gcctcttcaa tttgttttgg gtctgttttt gaagaaaagc gttcaaagac ttgcccatct
    10801 cgaccgatga gaaacttagc gaaattccat tcgattcgtt ttcctagtgg gccggatttc
    10861 tggtctttta accagacata gagagggtct gcttccttac cgttgacctt aatcttggca
    10921 aaacgtggga aggtggtttg aaaatgtagg ctacagaagg cgttgatttc ctctgcgctg
    10981 ccgggtgctt gtcccataaa ctgattgcaa gggaaatcca atatttcgaa gccctgatct
    11041 tgatagcgtt catagagttc ttgaagtccc tggtactggg gcgttaaacc acatccagta
    11101 gcagtgttga caatcaagag aactttgcca cgatagctat ccaagggagt tgcttggttg
    11161 ttttggttca aaacggaaaa atcataaagt gaagtcatga gggcctcttt tctttttcta
    11221 cattgtaaca gtttttactt ttttcgtcga gtcggatgga agatattgtt gaagaataag
    11281 ccttcaatat gatagaaacc gtttacaaat aactttaaaa atggtatgat ttaattaaac
    11341 cggtttactt agttgctata aatctctaat ttgagattta gttcctattg attttacaat
    11401 atgtttattg gagtgtatac atgcaaacaa aaacaaagaa gctcattgtg agtttgtctt
    11461 cacttgtttt atcaggattt ttattaaacc attatatgac agttggagcg gaagaaacga
    11521 ctacgaatac cattcagcaa agccagaagg aagttcagta tcagcaaagg gatacaaaaa
    11581 atttagttga aaatggtgat tttggtcaga cggaggacgg aagcagtccg tggacaggaa
    11641 gcaaagctca ggggtggtca gcttgggtag accagaagaa tagtgcagat gcctcaactc
    11701 gagtcattga ggctaaggat ggggctatca ctatctcaag ccatgagaaa ttaagggcag
    11761 cggttcaccg tatggttcct attgaagcta agaaaaagta taaactgcgt ttcaagatta
    11821 aaacagatca taaagtcggg attgccaaag ttcgtatcat tgaggaaagt gataaggaca
    11881 agcgattgtg gaattctgca acgacgtcag gaacaaagga ctggcagacc attgaagcag
    11941 actatagccc gactttagat gttgataaaa tcaagctgga gttattctat gaaacaggaa
    12001 ctgggactgt ttcctttaag gatattgagc tggtagaggt agcagaccag ccttctgagg
    12061 actatcaaac agataaacag cttgaggaaa agattgattt accaattgga aaaaaacatg
    12121 ttttttctct tgcggactat acttataagg tagaaaatcc tgacgttgct tcagtcaaaa
    12181 atggaatttt agaacctctt aaggaaggga caaccaatgt cattgtcagt aaagatggca
    12241 aggaagtgaa aaagattcct ttgaagattc tagcctctgt taaggatgca tacacagacc
    12301 gtttggatga ctggaatggc atcatcgctg ggaatcaata ctatgattct aaaaatgaac
    12361 agatggccaa attaaaccag gaattggaag gaaaggtagc tgatagccta tctagtattt
    12421 caagtcaggc ggaccgcacc tatttgtggg aaaaattttc aaattataaa atgtctgcaa
    12481 atctgactgc cacttatcgg aaattggagg agatggccaa gcaagtgacc aatccttctt
    12541 ctcgttatta tcaagatgaa actgtcgttc gaacagtcag ggattccatg gaatggatgc
    12601 ataaacatgt ctacaatagt gaaaagagca ttgttgggaa ctggtgggat tatgaaatcg
    12661 gtacacctcg tgccatcaac aataccttgt ctctgatgaa agaatacttc tctgatgagg
    12721 aaattaaaaa atatacagat gtgattgaaa aatttgtacc agatcccgaa catttccgaa
    12781 agacgactga taacccattt aaggctctag gtggaaactt agttgatatg ggaagagtaa
    12841 aagtaatagc tggtttactg cgtaaggatg atcaagaaat ttcttctacc attcgctcga
    12901 ttgagcaagt gttcaagttg gtagaccaag gtgaaggttt ttatcaagat ggatcctata
    12961 tcgaccatac caatgttgcc tatacgggtg cttatgggaa tgttttgatt gatggcctgt
    13021 ctcaactgtt gccagtcatt caaaagacca agaatccaat cgataaagat aaaatgcaaa
    13081 ccatgtacca ctggattgat aaatcgtttg ctcctttgct ggtgaatgga gagctgatgg
    13141 atatgagtcg tggacgctcg atcagtcgtg caaatagcga ggggcacgtg gccgcagtag
    13201 aagtactaag agggattcac cgaatagcgg atatgtctga aggagaaacc aaacaacgtt
    13261 tgcagagtct tgtgaagacc attgttcaat cggatagtta ttatgatgtc tttaagaatt
    13321 tgaagactta taaggatatc agtttgatgc aatccttgtt aagtgatgca ggagtcgcaa
    13381 gtgttccaag aacaagttac ctatctgcct ttaacaagat ggataaaaca gccatgtaca
    13441 atgcagagaa agggtttgga tttggcttgt cactcttttc cagtcgtacc ttgaattacg
    13501 aacacatgaa caaggaaaat aaacgtggtt ggtatacgag tgatgggatg ttctatcttt
    13561 acaatggcga tttgagtcac tatagcgatg gctactggcc aacagttaat ccatataaga
    13621 tgcctggtac aacagagacg gatgctaaga gagcggatag cgatacaggt aaagttttac
    13681 cgtctgcttt cgttggaacg agcaaactag atgatgccaa tgcgacagca accatggatt
    13741 tcaccaactg gaatcaaaca ttgactgctc ataagagctg gtttatgcta aaggataaga
    13801 tcgccttttt aggaagcaat atccaaaaca cttcaacaga tactgctgca actacaattg
    13861 accagagaaa actggaatca agtaatccat ataaagtcta tgtcaatgat aaagaagcct
    13921 cccttacaga acaagaaaag gattatcctg aaacccaaag tgtcttttta gaatcatccg
    13981 attcgaaaaa gaatattggt tactttttct ttaagaagag ttcaatcagt atgagtaagg
    14041 ctttgcaaaa gggagcctgg aaggatatca atgaaggaca gtcagacaag gaagttgaaa
    14101 atgaatttct tacgattagt caggctcata agcaaaatgg agattcttat ggctatatgc
    14161 tcatccctaa cgtgggtcgt gccaccttca atcaaatgat aaaagagtta gaaagaagcc
    14221 tcatcgaaaa taacgaaacc cttcagtctg tttatgatgc caaacaagga gtttggggca
    14281 ttgtgaaata tgatgattct gtctctacta tttccaacca attccaagtt ttgaaacgtg
    14341 gagtctatac cattcgaaaa gaaggggatg aatataagat tgcctactat aatcctgaaa
    14401 cccaggaatc agctccagat caggaagtct ttaaaaagct agagcaagca gctcagccac
    14461 aagtacagaa ttcaaaagaa aaggaaaaat ctgaagagga aaagaaccat tcggatcaaa
    14521 agaatctccc tcagacagga gaaggtcagt caatcttggc aagtctaggg ttcttgctac
    14581 ttggggcgtt ttatttattc cgtagaggaa agaacaacta atttgttcat catctagatg
    14641 aattacatga aactgtggaa aatagaaaaa atccgaagaa ggccaaatat cttcggattt
    14701 ttcttttaaa aaaggataag ttgatactta tcctttttac ttcattatgt gactatagcg
    14761 ttttgaaact agaataggac atcataactg ctaaaagatt tctataaatt catttgattt
    14821 tcctaatcaa tttattcgta tcctatttca ctctactata ttagtccgtc tcgcacctca
    14881 cggagcgaga caaaacaacc acccgctatg cgggtgcgcg tcgaaggtta taccaaaaaa
    14941 actccaaacg cgatacaata aaggtgttca atccacttgt aaagcgaaag gagaaaaaat
    15001 atggcacaaa aggctcatag tttatctcac acaaagtgga ggtgttctat cacattgtgt
    15061 tcacccctaa gtatagacga aaagtcatct ataatcaata tagaagtagt ttaggcgaaa
    15121 tatttcatcg cttgtgtagt tataaaggtg ttgaaatgat cgagggtcac ttaatgccag
    15181 accatgtaca catgttagtc agtattccac taaggctaag tgtttcgagt ttcatgggtt
    15241 atttaaaagg aaaaagtgca ctcatgatgt ttgacaaaca cgccaatctc aagtacaagt
    15301 ttgggaatcg gcatttctgg gtggaaggtt attatgtaag tccagtaggg cttaatgaag
    15361 ccacaattaa gaaatatagt caagattaaa gaaattatcc agtggatgat ttcttcacga
    15421 gtatgaaaat ttgagaacta gtaaagtatg atatatagta aaatgaaata agaacaggac
    15481 aaaatcgatc aggacagtca aatcgatttt taacaatgtt ttagaagtag aggtatacta
    15541 ttccagtttc aatctactat agcactagat aaattgagtg taaaagaata tgaggatccc
    15601 tttagggata gtggtaagta ataccaaagt ctcttaaaga ggcaagtgac gagtcaagag
    15661 caataaggct tgaacaacgt aaaagccagc gtctttaggc gctggctgat gatttgggct
    15721 tatagctctg ggataaacca cccgttagac gggtagttat gattttatct gagtgtaata
    15781 tactgttggg caatctcgct gatgcggtca aagttgcctt gggaagcgag tttattgagt
    15841 tcgccaccaa ttccaacggc atctgcacca gcagcgaacc attgagggat gttgtttagg
    15901 ccgactcctc cggttaccat tacggaaact tgtgggatcg gtgccttgac tgcagagata
    15961 tatgctggac tgagagtact acctgggaag agtttgatga tttcactacc ggcttcaagt
    16021 gcagtcgtga tctctgtgag ggtaatacag cctggaatgt acggtgtgct gtagagattg
    16081 cacattttcg cagtttcagc atggaaagat ggagaaacaa cgtaatttgc tccagctaga
    16141 atggcatctc tagcagttac ggcatcaagc acagtacctg caccgataca aacactctga
    16201 tcgtcctgat acaagtctac aagttccttg atgatttgtc ctgcatactg attggtatag
    16261 gcgatttcaa tagctttgat accgcccttg atacaagcaa tcgaggcttg tagtccttct
    16321 tcctttgtat ttcctcgaat gacagcgaca attttctgtt tttttagttc aataatcgta
    16381 tctgatttgg tcatgtaatt ctcctaacga atgatatctt gtgcatttgc cagtaaattt
    16441 tcaatactag ttgcggaagt ggagagatgg tctcctggaa gagtgcattt gagagttgcg
    16501 ctcgcaactg caaagtcaat ggtagttttt agggaggaat gatggagtag ttggtaaagg
    16561 gcaccagata taaaggcatc cccgctacca attcgttgat agactgcagt ttttagttgg
    16621 acagactctt caaatcgttc ttccagagca taggcttgat agacattttt gtcttgctca
    16681 tcactagatc ggagggtatg gaaaatggcc ttgaaaccat aggcttcttt taaaagtcgc
    16741 atgcgatttt ccacctcttc taggctagca ctgtctcttg gaaacatctc tagattttgg
    16801 tcatcaatca tgagaggatc aataccgaag caatagtcag taaaacgtgc aaacttagaa
    16861 aattcatact tggcttctag gactgaaatc atctttgttc tcagattgag atccattgaa
    16921 acgacaattc ctcggcgctt ggcttcttcc aagagtagga gaaggatcgc acggacctct
    16981 tgaccgatag ctatggtgat tccactaaaa tgaaaatggc taatcccctg aaagagagaa
    17041 tccatatcta gcatgtttgg ccgaatctgg ctgatactcg tatgcttacg atcgtagaaa
    17101 acttcacttt gacgacaacc aaagccgttc tccaaatagt agaggccgat tcgatcgcca
    17161 agccgacaga ttgaactggt atcgatttgg tgctgtttca agaatgtgag aaaacgatct
    17221 ccaatctcgt tggcagggag tgcggtaaag actttcgttg agatacccag ggcttgcaaa
    17281 ttacaagcga tgttaatttc tgatccgcca aaataagtcg aactggcaac atgatcgccg
    17341 atactggtgg catctaatgg tgagattcga attaatggtt cgccaaacag taatattttc
    17401 gtcatccatt agttcctttc tggtttagaa tagctttact tggctaatac ttctttcaaa
    17461 taagcagcga cttcatcatc ttggcagttt tcaaagaagt attcttggaa gtatttgcca
    17521 gagatggtgt ctttgaggaa gtcttggtcg attgttttaa ggatggtcat caaatcattg
    17581 tgggtgattt gtttcacctc gtttaagata cgagcgttgc gttgttcagg gattacacgt
    17641 tctcttgggt agccaccgcc catttcttca gcaaataagc gttcaaacat caatttgagg
    17701 gtcagttctg ccccccagcc aaatcctttg gcataaggga tagacaaggc gttaccacca
    17761 ttgatttgag aataaaggta agcgtcagtt gggtccactg ctagaccaca gacaacacca
    17821 gggaagctgt ttaaagcaag catagcccct acacccgtac cacagccggt aacaacaaag
    17881 tcaactgcct ttgtatttaa aaggatggca gccattagtc cgttctgcac ataagttaat
    17941 tgactttctc cttcttctcc acgcatacca tagttaaata attggtagtc ttttttatct
    18001 gtcgcttctt ttagactatc gtaaataatg tgattcttgc tagcttgact attttcattg
    18061 attaatgcga ttttcataag atcttctttc tatttttact caggttgttt tccgatgtag
    18121 gctaagatac cgccatctac atataggatg tggccattga caaaattgct ggcatcacta
    18181 gcgagaaaga cagcagggcc catcaaatct tcaggatttc cccaacgtgc agcaggtgtt
    18241 tttgcaatga tgaactggtc aaatgggtgg cgagaaccat cttcttgcaa ctcacgaaga
    18301 ggtgctgttt gaggagtggc aatataaccc ggtccaattc cgttacattg gatattggct
    18361 ccaccgtatt cagacgcaat gttgcgggtc aacattttca agcccccttt agcagcagca
    18421 taagcgctaa ctgtttcacg tcccagttcg ctcatcatcg aacaaatatt gataatcttt
    18481 ccatgccctt tctttatcat agaaggaata actgcctttg aaacgataaa tggtgcgttt
    18541 aagtcaatat cgatgacctt acggaaatca gcggcgctca tttcgcacat tggaactcgg
    18601 cggataatac cagcgttatt aacgaggatg tcaatgacac caacctcttg ttcgatttgc
    18661 ttgaccatgg cttggatacc gtcctcgtct gtcacgtcac agacatatcc atgggcttcg
    18721 atgccaactt cacgataagc ttcaatccct ttattgacca gatcttgatt gatatcgtta
    18781 aagacaatag tagcgccggc ttcagcgtag gatttggcaa tagcaaatcc aattccataa
    18841 gaagcgccgg tgatgagagc aatttttcct tttaaagaaa actgctcaat tgagaatgat
    18901 gtatttgtca tttgatactt cctttcaaat ttgttaagac ttctctataa ccaaattata
    18961 ttctagcaaa ccggttttgt caataaataa atatttttat ttataaaaag atttgttttc
    19021 ctgaaaaacg gaatgttttg aaatttctgt ttattaaaat ggttaaaaag ataatgaaag
    19081 cgctaatatt tttttaaaaa aactattgac aagataaaaa taaaggatta caatggggaa
    19141 tataaagtaa accggtaaac ctaaacaaga aaggagaaaa gatgaaaatt gtacttgtag
    19201 ggcatggaca ttttgctaca gggatttata gttctttaca attgattgca ggtaatcaag
    19261 aaaatgtgga ggcgattgac tttgtggaag gaatgtcagc agatgaactc aagcaaaaaa
    19321 tcttacttgc aatttcaaat gaagaagaag ttttaatcct aagtgatctc ttgggaggat
    19381 cgccattcaa ggtttcttct accataatgg gagaaaatcc agtcaaaaca atgaatgttc
    19441 tctcgggttt gaacttagcc atgttaatgg aagcagtctt tgctagaatg gctcatagct
    19501 ttgatgaggt tgttaataaa tcagtagtgg cggcccaggg cggagtcgta aatggtaaag
    19561 aattgttttc aacggatgca gaggaagaag atttcgaatc gggtatttaa agggtaaaag
    19621 aatgataaaa aaggttacga ttgaaaaaat aaaatcgcct gagcgcttct tagaagtacc
    19681 acttctgacg aaagaagaag tcggccaggc aatcgataag gttattcggc agttagaact
    19741 caaccttgac tatttcaagg aagatttccc gacgccagct acctttgata atgtctatcc
    19801 aatcatggat aacacggaat ggaccaatgg tttctggaca ggagaactgt ggttggctta
    19861 tgaatacagt caacaggatg catttaaaaa catcgctcat aaaaatgttc tttctttcct
    19921 ggatcgtgtc aataagagag tagaattgga tcaccatgat ctcggcttct tgtacacacc
    19981 gtcttgtatg gctgaatata agataaatgg agatggagag gctagagaag caaccttgaa
    20041 agctgcagat aagttgattg aacgctatca agaaaaaggt ggttttattc aagcttgggg
    20101 agacttgggc aagaaagagc attaccgttt gattatcgac tgcttgctca atatccaact
    20161 cttattcttt gcttatcaag aaacaggcga tcaaaaatac tacgatattg cagaaagtca
    20221 tttctatgct tcagctaata atgtaatccg tgatgacgct tcgtccttcc acaccttcta
    20281 ttttgatcct gagacaggtc aaccctttaa aggtgtaacg agacaagggt atagtgatga
    20341 ttcatgctgg gcacgtggtc aatcatgggg agtctatggt attcctttga cttatcgtca
    20401 cttaaaagac gagtcctgct ttgacttgtt taagggtgtg accaattatt tcttgaatcg
    20461 tctgccaaaa gatcatgtgt cctattggga tttgattttt aatgatggta gtgctcaatc
    20521 acgagattct tcagcaacag ctatcgccgt ctgtgggatt catgaaatgc taaaacatct
    20581 cccagaggtg gatgctgaca aagatattta taaacatgct atgcatgcca tgcttcgttc
    20641 cttgatcgaa cattatgcaa atgatcaatt tacccctggt gggacaagtc ttctccacgg
    20701 tgtgtactca tggcattcag gtaaaggagt ggatgaaggc aatatctggg gtgactacta
    20761 ttacctagaa gcccttatcc gtttctacaa agactggaac ctatattggt aggaggagaa
    20821 atatgacaat gccaaatatt attatgaccc gtatcgatga acggttgatt catggacaag
    20881 gacaactttg ggtaaaatac ctagcttgta atacggtcat tgttgccaat gacgaagtaa
    20941 gcacggacaa gatgcaacaa actctgatga aaacagttgt gccagactca gttgccatgc
    21001 gtttcttccc tttgcaaaag gtgattgata tcattcacaa ggctaatcct gctcaaacga
    21061 tctttatcgt tgtaaaggat gtaaaggacg ctttaacctt ggtagaaggt ggtgtcccta
    21121 tcaaagaaat caatattggg aacattcaca atgcccctgg taaagagcaa gtgacacgct
    21181 ccatcttcct gggtgaagag gacaaggcag ccctcaagga attaagccaa actcatcaag
    21241 taacatttaa tacgaaaaca actccaacag gaaatgatgg agctgttcaa gtcaacatta
    21301 tggactatat ttaaaagagg agatcgttat gtcgattaat gtatttcaag cgattttaat
    21361 tggattatgg acagctttct gttttagtgg aatgctgtta ggaatttaca ccaatagatg
    21421 tattgttctg tcatttggtg tcggaattat tctaggtgat ctgcctactg ctcttgcaat
    21481 gggagctatt ggtgaattgg cttatatggg attcggtgtt ggtgctggag gtactgttcc
    21541 accaaaccca atcggacctg gtatctttgg taccttgatg gctatcacta gtgctggtaa
    21601 agtcagtcca gaagcggctc ttgccctctc tactccgatt gctgtggcga ttcaattctt
    21661 acaaactttc gcctacactg tacgtgctgg tgcgcctgaa acggcgatga agcacttgaa
    21721 aaaccataat ttgaagaaat tcaagtttac tctaaatgca acaatttggt tgtttgcctt
    21781 tattggattt accttgggtt gcttgggtgc cctttcaatg gataccttgt tgaaactcgt
    21841 agactacatt ccaccggtat tacttacagg tttgacagtt gctggtaaaa tgctcccagc
    21901 tatcggtttt gcgatgatct tgtcagtgat ggctaagaaa gagttgattc cctttgtctt
    21961 gttgggatat gtttgtgcag cttatctaaa catcccaaca attggtattg caattgtagg
    22021 tactatcttt gctttgattg aattttataa caagccaaaa acagcgaatc atgtggtaga
    22081 ggaggaagca cacgatgact ggatctaaca aattaacaaa acgtgattat cttaaaacgt
    22141 ctttgcgggc attcttttgt caaaatggat ttaactatag taactatcaa gggttgggat
    22201 atgccaatgt gatgtatcct gctttgaaaa aacactatgg agaggatcag gaaggtttct
    22261 accaagcctt ggaagaaaac tgtgaattct ataataccaa cccacacttc ctgcctttta
    22321 ttaccagctt gcatcttgta atgttggaaa atggccgtcc ggcaaaagaa acacgtagca
    22381 tcaagatggc cttgatggga ccattggcag gtattgggga ttctctttct caattctgtt
    22441 tagctccatt gttctcaacc atcgcagctt cgtttgctca agaaggcttg gttgtcggtc
    22501 caatcttgtt cttccttgcg atgaatacga ttttaacagc gattaaattg tcaactggtc
    22561 tgtatggata caaactagga acaactgtga ttgataaact aagcgaacag atggcaacga
    22621 tttctcgtat tgccaatatt atcggtgtaa ccgtaattgc tggtttggca gcgacatctg
    22681 ttaagattat ggtgccgatt acctttgctg caggggaagt taaagcagac gctaaacaaa
    22741 gtatcgtaag tattcaggga atgcttgata aggttgctcc agctcttcta ccagccctat
    22801 ttacactttt agtttactac ttgatcaaag aaaagaaatg gacaacatat aaactcgtta
    22861 ttttaacagt tgtcatcgga attatcggaa gctggcttaa gattatagct taatggatac
    22921 aacattgttt tatggaatag tgattgtctt ggcagtgagt ccccttttac tgtcaagctt
    22981 tcattctatt cgtcagcaaa agttgcttcg caaacagacg gagcaacgac aagagtattt
    23041 agcttcttta acatctggtg atgaagtgtt gttattgtct ggaattcatg gaaaaatcat
    23101 ttctatcaaa gatgacttgg tctccttgca gattgcaaaa ggtgtggtca tctatgtaga
    23161 aaaggaaagt gtaatgggaa agacaaaaga actgcttttt aagtagttct ttttctggta
    23221 atagataatg aaagaagaaa gaagacaatt ttttgaaaga gtcgatggaa accaatgtcg
    23281 tgattatatc ttgtcgcact gttcaaaaga ctatgagaaa gtcaagagtt cccttgaacg
    23341 cttgatggac aatcgtttta tgtttgatag tccttgggat atggagcctt gttcaaaaat
    23401 ccatcaaatc cagccgatgg tatgggatca agtatttgaa gatgatccag aatgggctta
    23461 tatgctcaat cgacaagaat atctcttgca gtttatgata gggtatgtgg tagaaggaga
    23521 taaggactat attcaaaagt gcaagttctt tctatttgat tggattgagc aggtgagaga
    23581 attttctcct caatccttga tgactagaac cttggatacg ggtattcgtt cctttacttg
    23641 gttgaaacta ctcttgctcc tcttgaaatt tgacatgcta gaggagaaag aactagagaa
    23701 aattttggtc agtctagaaa agcagattga ctttatgaaa agctactatc gcgccaagta
    23761 cacccttagt aactggggga ttttacaaac aattccgatg cttgctatct attatttctt
    23821 ttcagataag atggacctag aagaagctta ccattttgct tcagaggagt tgaaacagca
    23881 aattgagaca cagattttag gagatggaag ccagtttgaa cagtcgattc tctatcatgt
    23941 agaggtttat aaagccttgc tggatttgtg tctcttgctt ccagacttgc aagatagtta
    24001 ccgagagttg ctggaaaaga tggcgaccta tattcaaatg atgacaggct tagatggacg
    24061 aactttggct tttggtgata gcgattctac agaaacgaca gaaattttga gcctgtctgc
    24121 tgtggttttg aacaaggaag accttcttaa cggtctggat gttaaagtcg atttgcttag
    24181 cctcttgttc ctggggcgag aaaaggtcaa gcgactgcag gaatttgaaa agagagcttg
    24241 gcagcctaag tccatgatct ttgaagactc tggacatgtc tgcattaagg atgaacatcg
    24301 ttatctattt ttcaaaaatg gtccgctagg aagtgcccat agccatagtg acgagaatag
    24361 tttttgctta cagtatcaag gacaacctat tttcatagat gctgggcgtt attcttatcg
    24421 ggagatatat gaacgttatc tcttaaagag tgcttggagt cattcgacct gcattgtaga
    24481 tgggaaagct ccggaaagaa tcacgggatc ctgggaatat gaatactatc ctcactccct
    24541 gttttgtcac cataaagaaa gggagggagt gcattatatt gaaggggctt attggtcagc
    24601 agaacctgat ttgccttatc ttcacaagag aaaaatcctc atgttggtag aggatgtctg
    24661 gctcttggtg gatgacatca ggtgtcaagg tcagcatgag gcgttgactc agtttatcct
    24721 tgacaaggat gtgacctatc aagatgggaa aatcaatcag ttgagactat ggagtgaagt
    24781 tgattttgat ttggaagata ccatcatttc tcctaaatac aatgagcttg aaagaagtaa
    24841 caaactcacc aagcgccaat tctttgagaa tcagatgctg gattatacca tcattgcgca
    24901 tgagagtttt gaaatcatcc gtcattctgt ctaccagaca gatgatcgtg aagtggaaaa
    24961 tgctctggct tttgaagtga aaaatgacga aacagacaag ctgattctgt tattaagcga
    25021 ggatatttgt gtaggtgaaa aattgtgcct cgttgacgga acaaaaatgc gtggaaaatg
    25081 tctagtatat gataaaataa atgagagaat gattcgcttg cagtgctaga aataggcatt
    25141 ttgaatagtg aatatgttat aataagtatt agtaggaggt gttttagatt ggagaagaaa
    25201 ctgaccataa aagacattgc ggaaatggct cagacctcga aaacaaccgt gtcattttac
    25261 ctaaacggga aatatgaaaa aatgtcccaa gagacacgtg aaaagattga aaaagttatt
    25321 catgaaacaa attacaaacc gagcattgtt gcgcgtagct taaactccaa acgaacaaaa
    25381 ttaatcggtg ttttgatcgg tgatattacc aacagtttct caaaccaaat tgttaaggga
    25441 attgaggata tcgccagcca gaatggctac caggtaatga taggaaatag taattacagc
    25501 caagagagtg aggaccggta tattgaaagc atgcttctct tgggagtaga cggctttatt
    25561 attcagccga cctctaattt ccgaaaatat tctcgtatca tcgatgagaa aaagaagaaa
    25621 atggtctttt ttgatagtca gctctatgaa caccggacta gctgggttaa aaccaataac
    25681 tatgatgccg tttatgacat gacccagtcc tgtatcgaaa aaggttatga gcattttctc
    25741 ttgattacag cggatacgag tcgtttgagt actcggattg agcgggcaag tggttttgtg
    25801 gatgctttaa cagatgctaa tatgcgtcac gccagtctaa ccattgaaga taagcatacg
    25861 aatttggaac aaattaagga atttttacaa aaagaaatcg atcccgatga aaaaactctg
    25921 gtatttatcc ctaactgttg ggccctacct ctagtcttta ccgttatcaa agagttgaat
    25981 tataacttgc cacaagttgg gttgattggt tttgacaata cggagtggac ttgcttttct
    26041 tctccaagtg tttcgacgct ggttcagccc tcctttgagg aaggacaaca ggctacaaag
    26101 attttgattg atcagattga aggccgtaat caagaagaaa ggcaacaagt cttggattgt
    26161 agtgtgaatt ggaaagagtc gactttctaa aatgaaggaa aatgacttgc aatctctgtt
    26221 aagaaataaa ataatcccac ctagaacaag ctaggtggga ttatttgctt atgaaatgag
    26281 aaattatggg agcaagctcc taaatcaact gtttttgatc tacttcttta actacttgat
    26341 aaaagttata gaagtaggcc aaacttgaaa tgatggttac gactaggaat attgaaaatt
    26401 tccattggac agggttggtt aaaagttgtg gaaaggatat gaggagaaag aagagggctg
    26461 cgttgaggac aggtatccgt tttgattgta ttttctcaag tcctttattg agcgcaggaa
    26521 gaaagaggag taggagtagt aaaactgtat gagaaacagc tcctgaaata agggcgaaga
    26581 aaaggaaaat actgataaaa acatgaatgt tcagtagtct agctagtgat ttcataaggc
    26641 acctcctaat cctggtcttt tttagctctt gcaatacgaa gtgagtcgac aatatgtatc
    26701 atcactccga aaaagaaagc tcccagtata gttttaaaaa tatgttttgt atttagaaga
    26761 gaactgataa aatttggatt ttcacttgtt agggtatcaa tgagtggaat tataaaaaat
    26821 atcactgttc cataaatcga acctgctttc agaccaggat aacgtaactg tttcttttct
    26881 tttttcatga gtttcctcct aatcctcatc ttgatttttc ttagtttttg caatgcgacg
    26941 ggagatgagg aactgtatgc tcgctccgaa gaaaatagaa ccgagaatac ttgatacacc
    27001 atttcttata gtgagaagag aatgaaaata gtcctgacct tcatctatga gtatactgag
    27061 aagaggagtt ataaaaaaca tccatagacc aaagaacaaa cctgctttca gacctgggta
    27121 gtgtagttgc ttgctttctt tctcattcag catatctggt tcaatgactg tgatgcctgt
    27181 ttttttcatt tggtaggtga catagccagc agcgatgagg gcaatcacta aaatcagagg
    27241 aggatagatt agagccactt cttgagggta tttataggct agaaggagtg gaataagatt
    27301 tccgaaaatc atcagataaa agaggacgat aaagacttgg ttcccaatac tatcggcctc
    27361 acgccgtttg tattcgtcaa ggggaccaga aataccgtat gtgcgtttga tcagtttttc
    27421 agtgaaggtt tcttttttca tgagtttgct ccttttttaa aaatcttcct cccaaaagag
    27481 actgttgagg tcagtttgga ggctgcgggc gagattgaga cagagttcca aggttggatt
    27541 gtacttgtcg ttttcaatca tattgatagt ctgtctcgag acaccgatat ccttggcgag
    27601 ttcgagctgg gaaataccca attccttgcg aaattctttc acacgattca tctggtctcc
    27661 tttctgattt atgtcgtata tatttgacta tattatagtc ttttaaacat aaagtgtcaa
    27721 gtatatttga catatttttt gaagaaatag tagtctcctt gtcctatttg tctgacaagt
    27781 gcaagctggt cggatttgtg gtaaaataga taagatatga caaaagaatt tcatcatgta
    27841 acggtcttac tccacgaaac gattgatatg cttgacgtaa aacctgacgg tatctacgtt
    27901 gatgcgactt tgggtggagc aggccatagc gagtatttat taagtaaatt aagtgaaaaa
    27961 ggccatctct atgcctttga ccaggatcag aatgccattg acaatgcgca aaaacgcttg
    28021 gcaccttaca ttgagaaggg aatggtgacc tttatcaagg ataacttccg tcatttacag
    28081 gcacgtttgc gcgaagctgg tgttcaggaa attgatggaa tttgttatga cttgggagtg
    28141 tctagtcctc aattggacca gcgtgagcgt ggtttttctt ataaaaagga tgcgccactg
    28201 gacatgcgga tgaatcagga tgctagtctg acagcctatg aagtggttaa tcactatgac
    28261 tatcatgatt tggttcgtat tttcttcaaa tacggtgagg ataaattctc taaacagatt
    28321 gcgcgtaaga ttgagcaagc gcgtgaagtg aagccgattg agacaacgac tgagttagca
    28381 gagattatca agttggtcaa acctgccaag gaactcaaga agaagggtca tcctgctaag
    28441 cagattttcc aggctattcg aattgaagtc aatgatgaac tgggagcggc agatgagtcc
    28501 atccagcagg ctatggatat gttggctctg gatggtagaa tttcagtgat tacctttcat
    28561 tccttagaag accgcttgac caagcaattg ttcaaggaag cttcaacagt tgaagttcca
    28621 aaaggcttgc ctttcatccc agatgatctc aagcccaaga tggaattggt gtcccgtaag
    28681 ccaatcttgc caagtgcgga agagttagaa gccaataacc gctcgcactc agccaagttg
    28741 cgcgtggcca gaaaaattca caagtaagag ggaaaaagat ggcagaaaaa atggaaaaaa
    28801 caggtcaaat actacagatg caacttaaac ggttttcgcg tgtggaaaaa gctttttact
    28861 tttccattgc tgtaaccact cttattgtag ccattagtat tatttttatg cagaccaagc
    28921 tcttgcaagt gcagaatgat ttgacaaaaa tcaatgcgca gatagaggaa aagaagaccg
    28981 aattggacga tgccaagcaa gaggtcaatg aactattacg tgcagaacgt ttgaaagaaa
    29041 ttgccaattc acacgatttg caattaaaca atgaaaatat tagaatagcg gagtaagata
    29101 tgaagtggac aaaaagagta atccgttatg cgaccaaaaa tcggaaatcg ccggctgaaa
    29161 acagacgcag agttggaaaa agtctgagtt tattatctgt ctttgttttt gccatttttt
    29221 tagtcaattt tgcggtcatt attgggacag gcactcgctt tggaacagat ttagcgaagg
    29281 aagctaagaa ggttcatcaa accacccgta cagttcctgc caaacgtggg actatttatg
    29341 accgaaatgg agtcccgatt gctgaggatg caacctccta taatgtctat gcggtcattg
    29401 atgagaacta taagtcagca acgggtaaga ttctttacgt agaaaaaaca caatttaaca
    29461 aggttgcaga ggtctttcat aagtatctgg acatggaaga atcctatgta agagagcaac
    29521 tctcgcaacc taatctcaag caagtttcct ttggagcaaa gggaaatggg attacctatg
    29581 ccaatatgat gtctatcaaa aaagaattgg aagctgcaga ggtcaagggg attgatttta
    29641 caaccagtcc caatcgtagt tacccaaacg gacaatttgc ttctagtttt atcggcctag
    29701 ctcagctcca tgaaaatgaa gatggaagca agagcttgct gggaacctct ggaatggaga
    29761 gttccttgaa cagtattctt gcagggacag acggcattat tacctatgaa aaggatcgtc
    29821 tgggtaatat tgtacccgga acagaacaag tttcccaacg aacgatggac ggtaaggatg
    29881 tttatacaac catttccagc cccctccagt cctttatgga aacccagatg gattcttttc
    29941 aagagaaggt aaaaggaaag tacatgacag cgactttggt cagtgctaaa acaggggaaa
    30001 ttctggcaac aacgcaacga ccgacctttg atgcagatac aaaagaaggc attacagagg
    30061 actttgtttg gcgtgatatc ctttaccaaa gtaactatga gccaggttcc actatgaaag
    30121 tgatgatgtt ggctgctgct attgataata atacctttcc aggaggagaa gtctttaata
    30181 gtagtgagtt aaaaattgca gatgccacga ttcgagattg ggacgttaat gaaggattga
    30241 ctggtggcag aatgatgact ttttctcaag gttttgcaca ctcaagtaac gttgggatga
    30301 ccctccttga gcaaaagatg ggagatgcta cctggcttga ttatcttaat cgttttaagt
    30361 ttggagttcc gacccgtttc ggtttgacgg atgagtatgc tggtcagctt cctgcggata
    30421 atattgtcaa cattgcgcaa agctcatttg gacaagggat ttcagtgacc cagacgcaaa
    30481 tgattcgtgc ctttacagct attgctaatg acggtgtcat gctggagcct aaatttatta
    30541 gtgccgttta tgatccaaat gatcaaactg ctcggaaatc tcaaaaagaa attgtgggaa
    30601 atcctgtttc taaagatgca gctagtctaa ctcggactaa catggttttg gtagggacgg
    30661 atccggttta tggaaccatg tataaccaca gcacaggcaa gccaactgta actgttcctg
    30721 ggcaaaatgt agccctcaag tctggtacgg ctcagattgc tgacgagaaa aatggtggtt
    30781 atctagtcgg gttaaccgac tatattttct cggctgtatc gatgagtccg gctgaaaatc
    30841 ctgattttat cttgtatgtg acggtccaac aacctgaaca ttattcaggt attcagttgg
    30901 gagaatttgc caatcctatc ttggagcggg cttcagctat gaaagactct ctcaatcttc
    30961 aaacaacagc taaagctttg gagcaagtaa gtcaacaaag tccttatcct atgcctagtg
    31021 tcaaggatat ttcacctggt gatttagcag aagaattgcg tcgcaatctt gtacaaccca
    31081 tcgttgtggg aacaggaacg aagattaaaa acagttctgc tgaagaaggg aagaatcttg
    31141 ccccgaatca gcaagtcctt atcttatctg ataaagtaga ggaagttcca gatatgtatg
    31201 gttggacaaa ggagactgct gagacccttg ctaagtggct caatatagaa cttgaatttc
    31261 aaggttcggg ctctactgtg cagaagcaag atgttcgtgc taacacagct atcaaggaca
    31321 ttaaaaaaat tacattaact ttaggagact aatatgttta tttccatcag tgctggaatt
    31381 gtgacatttt tactaacttt agtaggaatt ccggccttta tccaatttta tagaaaggcg
    31441 caaattacag gccagcagat gcatgaggat gtcaaacagc atcaggcaaa agctgggact
    31501 cctacaatgg gaggtttggt tttcttgatt acttctgttt tggttgcttt ctttttcgcc
    31561 ctatttagta gccaattcag caataatatg ggaatgattt tgttcatctt ggtcttgtat
    31621 ggcttggtcg gatttttaga tgactttctc aaggtctttc gtaaaatcaa tgaggggctt
    31681 aatcctaagc aaaaattagc tcttcagctt ctaggtggag ttatcttcta tcttttctat
    31741 gagcgcggtg gcgatatgct ttctgtcttt ggttatcaag tgcatctagg gattttctat
    31801 attgtcttcg ctcttttctg gctagtcggt ttttcaaacg cagtaaactt gacagacggt
    31861 gttgacggtt tagctagtat ttccgttgtg attagtttgt ctgcctatgg agttattgcc
    31921 tatgtgcaag gtcagatgga tattcttcta gtgattcttg ccatgattgg tggtttgctc
    31981 agttttttca tctttaacca taagcctgct aaggtcttta tgggtgatgt gggaagtttg
    32041 gccctaggtg ggatgctggc agctatctct atggctctcc accaagaatg gactctcttg
    32101 attatcggaa ttgtatatgt ttttgaaaca acttctgtta tgatgcaagt cagttatttc
    32161 aaactgacag gtggtaaacg tattttccgt atgacgcctg tacatcacca ttttgagctt
    32221 gggggattgt ctggtaaagg aaatccttgg agcgagtgga aggttgactt cttcttttgg
    32281 ggagttgggc ttctagcaag tctcctgacc cttgcaattt tgtatttgat gtaagaatgg
    32341 caccctgatg tttcagggtg tttttgtgtt taaatacaca atgaaaatca aagaacaaac
    32401 tagaaagcta actttaggct gctcaaaata tagtagattg aaactagaat agtacacctc
    32461 tacttctaaa acatttttag aaatcgattt gactgtcctg aacgatttat cctgttctta
    32521 tttcatttta ctatacagtt ttgagatggt tgatagaact gacgaagtca gctcaaaaca
    32581 ctgttttgag gttgtagaca aggcgaagct gatgtggttt gaagaggttt tcgaagagtg
    32641 taaaaaaata ttggtcagtt aaagtcaaaa ctcttgacct tttctgacca atgtagtata
    32701 ttatgaacgt aaggtaaatg aaagccttac tagaacactt atttaaagta aaatagaaag
    32761 aggtgagtct atgtttcatc tagcaatctt cagaggtaaa gatagtctac tcctgcttga
    32821 aaaagaaaaa ccagaaatag tacgtagggt agcgatctag ctagtctaaa ttttttaaaa
    32881 caatggtcaa agatagtcaa tatcagtaat cataactaag taaacaaaaa gaggtaaaga
    32941 atatgaataa caactttaat aattttaata acatggatga tttatttaac caattgatgg
    33001 gtggtatgcg aggatatagt tctgaaaatc gccgttactt aattaatgga cgcgaagtca
    33061 cacctgagga atttgctcac tatcgtgcga ctggtcaatt accaggaaat gcagaaactg
    33121 atgtgcaaat gccacaacag gcatcaggta tgaaacaaga cggtgtcctt gcaaaactag
    33181 gtcgaaactt aacagcagaa gcgcgtgagg gcaagttgga tcctgttatc ggacgaaaca
    33241 aggaaattca agaaacatct gaaatcctct cacgccgcac caagaacaat cctgttttgg
    33301 tcggagatgc aggtgttggt aagacagcag ttgtcgaagg tctagcgcaa gccattgtga
    33361 acggagatgt tcctgctgct atcaagaaca aggaaattat ttccattgat atctcaggtc
    33421 ttgaggctgg tactcaatac cgtggtagct ttgaagaaaa tgtccaaaac ttagtcaatg
    33481 aagtgaaaga agcagggaat attatcctct tctttgatga aattcaccaa attcttggtg
    33541 ctggtagcac tggtggagac agtggttcta aaggacttgc ggatattctc aagccagctc
    33601 tctctcgtgg agaattgaca gtgattgggg caacaactca agacgaatac cgtaacacca
    33661 tcttgaagaa tgctgctctt gctcgtcgtt tcaacgaagt gaaggtcaat gctccttcag
    33721 cagagaatac ttttaaaatt cttcaaggca ttcgtgacct ctatcaacaa caccacaatg
    33781 tcatcttgcc agacgaagtc ttgaaagcag cggtggatta ttctgttcaa tacattcctc
    33841 aacgtagctt gccagataag gctattgacc ttgtcgatgt aacggctgct cacttggcgg
    33901 ctcaacatcc agtaacagat gtgcatgctg ttgaacgaga aatcgaaacg gaaaaagaca
    33961 agcaagaaaa agcagttgaa gcagaagatt ttgaagcagc tctaaactat aaaacacgca
    34021 ttgcagaatt ggaaaggaaa atcgaaaacc acacagaaga tatgaaagtg actgcaagtg
    34081 tcaacgatgt ggctgaatct gtggaacgaa tgacaggtat cccagtatcg caaatgggag
    34141 cttcagatat cgaacgtttg aaagatatgg ctcatcgctt gcaagaaaag gtgattggtc
    34201 aagataaggc cgtagaagtt gtagctcgtg ctatccgtcg taaccgtgct ggttttgatg
    34261 aaggaaatcg cccaatcggc agcttcctct ttgtagggtc tactggggtt ggtaagacgg
    34321 agcttgctaa gcaattggca ctcgatatgt ttggaaccca ggatgcgatt atccgtttgg
    34381 atatgtctga atacagtgac cgcacagctg tttctaagct aattggtaca acagcaggct
    34441 atgtgggtta tgatgacaat agcaatacct taacagaacg tgttcgtcgc aatccatact
    34501 ctatcattct cttggatgaa attgaaaagg ctgatcctca agttattacc cttctcctcc
    34561 aagttctaga tgatggtcgt ttgacagatg gtcaaggaaa tacagtaaac ttcaagaata
    34621 ctgtcgttat tgcgacctca aatgctggat ttggctatga agccaacttg acagaagatg
    34681 cggataaacc agaattgatg gaccgtttga aacccttctt ccgtccagaa ttcctcaacc
    34741 gctttaatgc agtcatcgag ttctcacact tgactaagga agacctttct aagattgtag
    34801 atttgatgtt ggctgaagtt aaccaaacct tggctaagaa agacattgac ttggtagtta
    34861 gtcaagcggc taaagattat atcacagaag aaggttacga cgaagtcatg ggggttcgtc
    34921 ctctccgtcg cgtggttgaa caagaaattc gtgataaggt gacagacttc cacttggatc
    34981 atttagatgc taaacatctg gaagcagata tggaagatgg cgttttggtt attcgtgaga
    35041 aagcctaaga tagaattttg aggataaaaa agaaggagcc agctgaaaaa aactggttcc
    35101 tttttaggta cgacaggcat gtcgtatagt agaagtgtat tattccagtt tcaatatact
    35161 atagtagctc agaagtcggt acttaaacgt gctatatcaa aaccagtcct tgaaaaacgt
    35221 ggactggttt cgtgtttgga ttattacctt gaacgacatg cgttaaaagt tagttgaacc
    35281 gccgtatgcc gaacggtacg tacggtggtg tgagaggggc tagagattat cccctactcg
    35341 attgtctata gctatagggg taaagttatt agagaggttg ctagtttata gagacatctt
    35401 gatttgtaaa aagttaaatt ttagacaatt atccccttta aaaaatctat taaaccatag
    35461 ctagttgaag taaattttta tagaacataa ttttatttat caagacattg tagagttgag
    35521 gcaaattgaa aaagaaagtt taaaagttga taataagtca ataagaaagc tattaattct
    35581 aacgagatta tttgatagta atttgttttt tcagctacta ttcggacaat gttattataa
    35641 taaacacagg agagaacacc agaaggtagg gacatcagaa gaaatagttc aggatatagt
    35701 taacataatc atcaaagaag ctcctagact cgctaatgtt aatttggaaa catattatcc
    35761 agatgaatat atgtcaaata cattgaagca attactactt tttagagagg agttcataaa
    35821 aaatattttg aatgggattg atgtggatga aacagtagta atagaaaatg attttgtaga
    35881 agagttggag aactttttaa aagagaatga tttgctagat ttttcaaata gcatattttt
    35941 tcagttatct ggagataaag taatagtgaa taatatttat ccaggatatt tagcatattt
    36001 taataggttc cttacatttt atccgaaaat attcgctatt aaagaagttg gagaatatat
    36061 tgacttttta aattttgaaa agagaattgc ggatatgttt tattgttggg gatttaatgc
    36121 aaattctaga gtgttgacag ctgaaaaaat aattgaaatc ccaaatcacc aaatcaatgc
    36181 taagtacata aaaaaagtta taaaaatgag tgaactcttg tttggtgttg atagtaataa
    36241 cagaattcgg ttgcttaaca atagaaggga attgataaaa actattttcc aaggttctgt
    36301 aattaagtca gcaattcctg ctctagctgc tactttggat acaatcagta acagtggatc
    36361 atttcaaatt tctttatcaa agcagataat taataattta gtattaagtg gtaaagataa
    36421 agttacaatt cctaggatag agttagataa tgttgttctt tcaagacaga agattattgt
    36481 atcagtttcg tatataaatg attttttgga tttgagattt ccagataaaa tagaatacat
    36541 tttaaatttt ttagaaggat ctggtttcaa tactaaagta atggtctact ttgggaaaat
    36601 tgtagaagaa gataagaact attttgttaa tcttgaaaaa cctcagtatt ttgattttac
    36661 cagtatactt ttcaataagt tattctttaa agaattaaac aagtttgatt acatggttat
    36721 tgaagaactc attccaaatc ttgatgaaga tgtaatgatg acagagtata taaaagagta
    36781 tactgaatag gagcaatcta ttatgatttt aagtaaagta cgttgttaca tatataattc
    36841 taaaattaga ggtaaagttc tgtatgaatt atatgaattt ataaatgaaa ataagcaatt
    36901 gatggacgca attaattcaa ttaaagttga cagtagtaat ggttttagta ttcaaatatt
    36961 acatttagga gaacagcaaa caactgtctt attaacagat ttttttacta aaactttaga
    37021 cttgtttaag gaatttaggg ttacaaataa gagtactctt gagcaggtga aaaatcaaat
    37081 tagcatacta aattcttctg gtccaaaaat ggatttaac
//
LOCUS       DAVBEO010000017        34466 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 009
            SAMEA1678075-rid20185393.denovo.017, whole genome shotgun sequence.
ACCESSION   DAVBEO010000017 DAVBEO010000000
VERSION     DAVBEO010000017.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678075
            Sequence Read Archive: ERR226392
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 34466)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34466)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980207.1
            Genome Coverage       :: 150x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:50:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 72 of 147
            Pseudo Genes (incomplete)         :: 72 of 147
            Pseudo Genes (internal stop)      :: 42 of 147
            Pseudo Genes (multiple problems)  :: 32 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34466
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678075-rid20185393.denovo.017"
                     /strain="KS 009"
                     /db_xref="taxon:1313"
     gene            143..361
                     /gene="infA"
                     /locus_tag="VQ543_000871"
     CDS             143..361
                     /gene="infA"
                     /locus_tag="VQ543_000871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003130554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-1"
                     /protein_id="HET2611616.1"
                     /translation="MAKDDVIEVEGKVVDTMPNAMFTVELENGHQILATVSGKIRKNY
                     IRILAGDRVTVEMSPYDLTRGRITYRFK"
     gene            386..502
                     /gene="rpmJ"
                     /locus_tag="VQ543_000872"
     CDS             386..502
                     /gene="rpmJ"
                     /locus_tag="VQ543_000872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L36"
                     /protein_id="HET2611617.1"
                     /translation="MKVRPSVKPICEYCKVIRRNGRVMVICPANPKHKQRQG"
     gene            520..885
                     /gene="rpsM"
                     /locus_tag="VQ543_000873"
     CDS             520..885
                     /gene="rpsM"
                     /locus_tag="VQ543_000873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S13"
                     /protein_id="HET2611618.1"
                     /translation="MARIAGVDIPNDKRVVISLTYVYGIGLATSKKILAAAGISEDVR
                     VRDLTSDQEDAIRREVDAIKVEGDLRREVNLNIKRLMEIGSYRGIRHRRGLPVRGQNT
                     KNNARTRKGKAVAIAGKKK"
     gene            903..1286
                     /gene="rpsK"
                     /locus_tag="VQ543_000874"
     CDS             903..1286
                     /gene="rpsK"
                     /locus_tag="VQ543_000874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003130556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S11"
                     /protein_id="HET2611619.1"
                     /translation="MAKPTRKRRVKKNIESGIAHIHATFNNTIVMITDVHGNAIAWSS
                     AGALGFKGSRKSTPFAAQMASEAAAKSAQEHGLKSVEVTVKGPGSGRESAIRALAAAG
                     LEVTAIRDVTPVPHNGARPPKRRRV"
     gene            1329..2264
                     /locus_tag="VQ543_000875"
     CDS             1329..2264
                     /locus_tag="VQ543_000875"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit alpha"
                     /protein_id="HET2611620.1"
                     /translation="MIEFEKPNITKIDENKDYGKFVIEPLERGYGTTLGNSLRRVLLA
                     SLPGAAVTSINIDGVLHEFDTVPGVREDVMQIILNIKGIAVKSYVEDEKIIELDVEGP
                     AEVTAGDILTDSDIEIVNPDHYLFTIGEGSSLKATMTVNSGRGYVPADENKKDNAPVG
                     TLAVDSIYTPVTKVNYQVEPARVGSNDGFDKLTLEILTNGTIIPEDALGLSARILTEH
                     LDLFTNLTEIAKSTEVMKEADTESDDRILDRTIEELDLSVRSYNCLKRAGINTVHDLT
                     EKSEAEMMKVRNLGRKSLEEVKLKLIDLGLGLKDK"
     gene            2276..2662
                     /gene="rplQ"
                     /locus_tag="VQ543_000876"
     CDS             2276..2662
                     /gene="rplQ"
                     /locus_tag="VQ543_000876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002887523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L17"
                     /protein_id="HET2611621.1"
                     /translation="MAYRKLGRTSSQRKAMLRDLTTDLLINESIVTTEARAKEIRKTV
                     EKMITLGKRGDLHARRQAAAFVRNEIASENYDEATDKYTSTTALQKLFSEIAPRYAER
                     NGGYTRILKTEPRRGDAAPMAIIELV"
     gene            2927..3193
                     /locus_tag="VQ543_000877"
     CDS             2927..3193
                     /locus_tag="VQ543_000877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002905356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACT domain-containing protein"
                     /protein_id="HET2611622.1"
                     /translation="MKAIITVVGKDKSGIVAGVSGKIAELGLNIDDISQTVLDEYFTM
                     MAVVSSDEKQDFTYLRNEFEAFGQTLNVKINIQSAAIFEAMYNI"
     gene            3203..4540
                     /locus_tag="VQ543_000878"
     CDS             3203..4540
                     /locus_tag="VQ543_000878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018166727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PFL family protein"
                     /protein_id="HET2611623.1"
                     /translation="MDIRQVTETIAMIEEQNFDIRTITMGISLLDCIDPDINRAAEKI
                     YQKITTKAANLVAVGDEIAAELGIPIVNKRVSVTPISLIGAATDATDYVVLAKALDKA
                     AKEIGVDFIGGFSALVQKGYQKGDEILINSIPRALTETDKVCSSVNIGSTKSGINMTA
                     VADMGRIIKETANLSDMGAAKLVVFANAVEDNPFMAGAFHGVGEADVIINVGVSGPGV
                     VKRALEKVRGQSFDVVAETVKKTAFKITRIGQLVGQMASERLGVEFGIVDLSLAPTPA
                     IGDSVARVLEEMGLETVGTHGTTVALALLNDQVKKGGVMACNQVGGLSGAFIPVSEDE
                     GMIAAVQNGSLNLEKLEAMTAICSVGLDMIAIPEDTPAETIAAMIADEAAIGVINMKT
                     TAVRIIPKGREGDMIEFGGLLGTAPVMKVNGASSVDFISRGGQIPAPIHSFKN"
     gene            4784..5476
                     /locus_tag="VQ543_000879"
     CDS             4784..5476
                     /locus_tag="VQ543_000879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HET2611624.1"
                     /translation="MVKVRLYLVRHGKTMFNTIGRAQGWSDTPLTAEGERGIQELGIG
                     LRESDLQFERAYSSDSGRTIQTMGIILEELGLQGKIPYRMDKRIREWCFGSFDGAYDG
                     DLFMGIIPRIFNVDHVHQLSYAELAEGLVEVDTAGWAEGWEKLSGRIKEGFEMIAKEM
                     EDQGGGNALVVSHGMTIGTIVYLINGMHPHGLDNGSVTILEYEDGQFRVEVVGDRSYR
                     ELGCEKMEEGSI"
     gene            complement(5579..7224)
                     /locus_tag="VQ543_000880"
                     /pseudo
     CDS             complement(5579..7224)
                     /locus_tag="VQ543_000880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520796.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
     gene            complement(7214..7519)
                     /locus_tag="VQ543_000881"
                     /pseudo
     CDS             complement(7214..7519)
                     /locus_tag="VQ543_000881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809465.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TOBE domain-containing protein"
     gene            complement(7646..8305)
                     /locus_tag="VQ543_000882"
     CDS             complement(7646..8305)
                     /locus_tag="VQ543_000882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2611625.1"
                     /translation="MSEIEIINAKKIYHDVPVIENLNITIPKGSLFTLLGASGCGKTT
                     LLRMIAGFNSIEGGEFYFDDTKINNMEPSKRNIGMVFQNYAIFPHLTVRDNVAFGLMQ
                     KKVPKEELIQQTNKYLELMQIAQYADRKPDKLSGGQQQRVTLACALAVNPSVLLMDEP
                     LSNLEAKLRLDMRQAIREIQHEVGITTVYVTHDQEEAMAISDQIAVMKDGVIQQIGRP
                     K"
     gene            complement(8318..9439)
                     /locus_tag="VQ543_000883"
                     /pseudo
     CDS             complement(8318..9439)
                     /locus_tag="VQ543_000883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931989.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
     gene            complement(10027..10803)
                     /locus_tag="VQ543_000884"
     CDS             complement(10027..10803)
                     /locus_tag="VQ543_000884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000406168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl-radical enzyme activating protein"
                     /protein_id="HET2611626.1"
                     /translation="MEISKGIIFNIQHFSIHDGPGIRTTVFLKGCPLRCPWCSNPESQ
                     RMKPEKMKDAQREKFTLVGEEKTVEEIITEVLKDKEFYEESGGGLTLSGGEIFAQFEF
                     AKAILKSAKEHHIHTAIETTAFVDHEKFIDLIQYVDFIYTDLKHYNSIKHKKVTGVFN
                     QMIIKNIHYAFSQNKTIVLRIPVIPNFNNSLEDAEKFATLFNSLNIDQVQLLPFHQFG
                     ENKYRLLNRKYEMDGINALHPEDLIDYQKVFLNHHINCYF"
     gene            10925..11671
                     /locus_tag="VQ543_000885"
     CDS             10925..11671
                     /locus_tag="VQ543_000885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000824973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HET2611627.1"
                     /translation="MKRLEQIIKLVSEYEKIDVNTLSEKLNVSKVTIRKDLDKLESKG
                     LLHREHGYAVLNSGDDLNVRLSINYEIKRKIVQEAVKLVSDNETIMIESGSTCALLAE
                     EICKQKRNVTIVTNSFFIANFVRAYDSCRIIVLGGEFQKDSQVTVGPLLKEMIQTFHV
                     HQAFVGTDGYDKEMGFTGKDLMRSEVVQYISAASDKVIVLTDSSKFDKRGTVRRFALS
                     QVYEVITDEKLSKQNIATLENAGIMVKVVS"
     gene            11684..12664
                     /locus_tag="VQ543_000886"
     CDS             11684..12664
                     /locus_tag="VQ543_000886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001070834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-binding transcriptional regulator"
                     /protein_id="HET2611628.1"
                     /translation="MNQDRNKLLSKIAYLYYIENLNQSQIAAKLGIYRTSISRMLTEA
                     RNAGIVKIEIENFDTNMFKLENYVKEKYGLESLEIIPNEFDDNPTILSERISQVAAGV
                     LRNLIDDNMKIGFSWGKSLSNLVDLIHSKSVRNVHFYPLAGGPSHIHAKYHVNTLIYE
                     MSRKFHGECTFMNATIVQENKLLADGILQSRYFENLKNSWKDLDIAVVGIGDFSNKGK
                     HQWLDMLTEDDFKELTKVKTVGEICCRFFDSKGKEVYENLQERTIAISLEDLKNIPQS
                     LAVAYGDTKVSSILSVLRANLVNHLITDKNTILKVLEEDGDLTFREILGE"
     gene            12859..13179
                     /locus_tag="VQ543_000887"
     CDS             12859..13179
                     /locus_tag="VQ543_000887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000402908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HET2611629.1"
                     /translation="MEIIVPDQIIMGLILYAGDAKQHIYKALDYIKNGTCERCEEEIQ
                     LADAALLEAHNLQTKFLAQEASGTKTEITALFVHSQDHLMTSMTEINLIKEIISLRKE
                     LHKK"
     gene            13225..13533
                     /locus_tag="VQ543_000888"
     CDS             13225..13533
                     /locus_tag="VQ543_000888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000238716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HET2611630.1"
                     /translation="MVKIGLFCAAGFSTGMLVNNMKIAAQSSGVEAEIEAFSQSKLAD
                     YAPNIDVALLGPQVAYTLDKSKEICDKCDVPIAVIPMMDYGMLDGKKVLDLALSLISG
                     "
     gene            13550..14848
                     /locus_tag="VQ543_000889"
     CDS             13550..14848
                     /locus_tag="VQ543_000889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000041357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HET2611631.1"
                     /translation="MSKMDVQKIIAPMMKFVNMRGIIALKDGMLAILPLTVVGSLFLI
                     MGQLPFEGLNKSIASVFGANWTEPFMQVYSGTFAIMGLISCFSIAYSYAKNSGVEALP
                     AGVLSVSAFFILLRSSYIPKQGEAIGDAISKVWFGGQGIIGAIIIGLVVGSIYTFFIK
                     RKIVIKMPEQVPQAIAKQFEAMIPAFVIFLSSMIVYILAKSLTNGGTFIEMIYSAIQV
                     PLQGLTGSLYGAIGIAFFISFLWWFGVHGQSVVNGVVTALLLSNLDANKAMLASANLS
                     LENGAHIVTQQFLDSFLILSGSGITFGLVVAMLFAAKSKQYQTLGKVAAFPAIFNVNE
                     PVVFGFPIVMNPVMFVPFILVPVLAAVIVYGAIATGFMQPFSGVTLPWSTPAILSGFL
                     VGGWQGVITQLVILAMSTLVYFPFFKVQDRLAYQNEIKQS"
     gene            14999..17437
                     /locus_tag="VQ543_000890"
     CDS             14999..17437
                     /locus_tag="VQ543_000890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl radical protein"
                     /protein_id="HET2611632.1"
                     /translation="MVNTEVARTTIKTEYFGSLTERMNKYREDVLNKKPYIDAERAVL
                     ATRAYERYKEQPNVLKRAYMLKEILENMTIYIEEESMIAGNQASSNKDAPIFPEYTLE
                     FVLNELDLFEKRDGDVFYITEETKEQLRSIAPFWENNNLRARAGALLPEEVSVYMETG
                     FFGMEGKMNSGDAHLAVNYQKLLQFGLRGFEERARKAKVALDLTDPASIDKYHFYDSI
                     FIVIDAIKVYAKRFVALAKSLAENANPKRKKELLEIADICSRVPYEPATTFAEAIQSV
                     WFIQCILQIESNGHSLSYGRFDQYMYPYMKADLESGKETEDSIVERLTNLWIKTITIN
                     KVRSQSHTFSSAGSPLYQNVTIGGQTRDKKDAVNPLSYLVLKSVAQTHLPQPNLTVRY
                     HAGLDARFMNECIEVMKLGFGMPAFNNDEIIIPSFIAKGVLEDDAYDYSAIGCVETAV
                     PGKWGYRCTGMSYMNFPKVLLITMNDGIDPASGKRFAPSFGHFKDMKNFSELENAWDK
                     TLRYLTRMSVIVENSIDLSLEREVPDILCSALTDDCIGRGKHLKEGGAVYDYISGLQV
                     GIANLSDSLAAIKKLVFEEERISPSQLWHALETDYAGEEGKVIQEMLIHDAPKYGNDD
                     DYADKLVTAAYDIYVDEIAKYPNTRYGRGPIGGIRYSGTSSISANVGQGRGTLATPDG
                     RNAGTPLAEGCSPSHNMDQHGPTSVLKSVSKLPTDEIVGGVLLNQKVNPQTLAKEEDK
                     LKLIALLRTFFNRLHGYHIQYNVVSRETLIDAQKHPEKHRDLIVRVAGYSAFFNVLSK
                     ATQDDIIGRTEHTL"
     gene            17456..18124
                     /locus_tag="VQ543_000891"
     CDS             17456..18124
                     /locus_tag="VQ543_000891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000395441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HET2611633.1"
                     /translation="MEFMLDTLNLDEIKKWSEILPLAGVTSNPTIAKREGSINFFERI
                     KDVRELIGSTPSIHVQVISQDFEGILKDAHEIRRQAGDDIFIKVPVTPAGLRAIKVLK
                     KEGYHITATAIYTVIQGLLAIEVGADYLAPYYNRMENLNIDSNSVIRQLALAIDRQNS
                     PSKILAASFKNVAQVNNALAAGAHAVTAGADVFESAFAMPSIQKAVDDFSDDWFVTQN
                     SRSI"
     gene            18142..19230
                     /locus_tag="VQ543_000892"
     CDS             18142..19230
                     /locus_tag="VQ543_000892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol dehydrogenase"
                     /protein_id="HET2611634.1"
                     /translation="MRIFASPSRYIQGENALFENAKSILDLGNYPILLCDQLVYDIVG
                     KRFEDYLHRYGFHIVLALFNGEASDNEINRVVALAEKENCDSIIGLGGGKTIDSAKAI
                     ADLIEKPVIIAPTIASTDAPVSALSVIYTDEGAFDHYLFYSKNPDLVLVDTKVISQAP
                     KRLLASGIADGLATWVEARAVMQANGKTMLGQQQTLAGVAIAKKCEETLFADGLQAMA
                     ACEAKVVTPALENIVEANTLLSGLGFESGGLAAAHAIHNGFTALTGDIHHLTHGEKVA
                     YGTLVQLLLENRPKEELDKYIEFYKKIGMPTTLKEMHLDQVGYDDLIKVGKQATMEGE
                     TIHQMPFKISPSDVAQAIIAVDAYVNSK"
     gene            19685..22186
                     /locus_tag="VQ543_000893"
     CDS             19685..22186
                     /locus_tag="VQ543_000893"
                     /EC_number="6.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014639013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine--tRNA ligase"
                     /protein_id="HET2611635.1"
                     /translation="MSFYNHKEIEPKWQGYWAEHHTFKTGTDASKPKFYALDMFPYPS
                     GAGLHVGHPEGYTATDILSRYKRAQGYNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTA
                     ENIANFKRQINALGFSYDWDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVE
                     ELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLNDLDELDWSESIKD
                     MQRNWIGKSTGANVTFKVKGTDKEFTVFTTRPDTLFGATFTVLAPEHELVDAITSTEQ
                     AEAVADYKHQASLKSDLARTDLAKEKTGVWTGAYAINPVNGKEIPIWIADYVLASYGT
                     GAVMAVPAHDQRDWEFAKQFDLPIVEVLEGGNVEEAAYTEDGLHVNSDFLDGLNKEDA
                     IAKIVAWLEEKGCGQEKVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLV
                     LPVTKDIRPSGTGESPLANLTDWLEVTREDGVKGRRETNTMPQWAGSSWYYLRYIDPH
                     NTEKLADEDLLKQWLPVDIYVGGAEHAVLHLLYARFWHKFLYDLGVVPTKEPFQKLFN
                     QGMILGTSYRDHRGALVATDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDV
                     VEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLIRSKEIVAENNGALD
                     KVYNETVKAVTEQIDSLKFNTAIAQLMVFVNAANKEDKLYVDYAKGFIQLIAPFAPHL
                     AEELWQTVAATGESISYVTWPTWDESKLVEDEIEIVVQIKGKVRAKLMVAKDLSREEL
                     QEIALADEKVKAEIDGKEIVKVISVPNKLVNIVVK"
     gene            22380..23075
                     /locus_tag="VQ543_000894"
     CDS             22380..23075
                     /locus_tag="VQ543_000894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001144916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET2611636.1"
                     /translation="MPVNEYGQMIGESMEGYTPGELPSIDFLEGRYARIEALSVEKHA
                     EDLLAVYGPDTPQEMWTYLFQEPVADMGELVSLLHQMLARKDRFYYAIIDKATGKALG
                     SFSLMRIDQNNRVIEVGAVTFSPELRGTRIGTEAQYLLARYVFEELNYRRYEWKCDAL
                     NLPSRRAAERLSFIYEGTFRQAVVYKGRTRDTDWLSMIDKDWPQVKDRLETWLRPENF
                     DKNGQQYKSLREL"
     gene            23087..23503
                     /locus_tag="VQ543_000895"
     CDS             23087..23503
                     /locus_tag="VQ543_000895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET2611637.1"
                     /translation="MITIKKQEIVKLEDVLHLYQAVGWTNYTHQPEMLEQALSHSLVI
                     YLALDGDAVVGLIRLVGDGFSSVLVQDLIVLPIYQRQGIGSALMKEALEDYKDAYQVQ
                     LVTEETERTLGFYRSMGFEILSTYNCIGMTWMNRKK"
     gene            complement(24130..24222)
                     /locus_tag="VQ543_000896"
     CDS             complement(24130..24222)
                     /locus_tag="VQ543_000896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="HET2611638.1"
                     /translation="MMELVLKTIIGPIVVGVVLRIVDKWLNKDK"
     gene            24383..25354
                     /gene="ruvB"
                     /locus_tag="VQ543_000897"
     CDS             24383..25354
                     /gene="ruvB"
                     /locus_tag="VQ543_000897"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000502070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration DNA helicase
                     RuvB"
                     /protein_id="HET2611639.1"
                     /translation="MGDEELVERTLRPQYLREYIGQDKVKDQLQIFIEAAKMRDEALD
                     HVLLFGPPGLGKTTMAFVIANELGVNLKQTSGPVIEKAGDLVAILNELEPGDVLFIDE
                     IHRLPMSVEEVLYSAMEDFYIDIMIGAGEGSRSVHLELPPFTLIGATTRAGMLSNPLR
                     ARFGITGHMEYYAHADLTEIVERTADIFEMEITHEAASELALRSRGTPRIANRLLKRV
                     RDFAQIMGNGVIDDIITDKALTMLDVDHEGLDYVDQKILRTMIEMYSGGPVGLGTLSV
                     NIAEERETVEDMYEPYLIQKGFIMRTRSGRVATAKAYEHLGYEYSEK"
     gene            25335..25907
                     /locus_tag="VQ543_000898"
     CDS             25335..25907
                     /locus_tag="VQ543_000898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001098890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase family protein"
                     /protein_id="HET2611640.1"
                     /translation="MNTVKNKQEILEAFRENPDMMAILTIIRDLGLKDSWLAAGSVRN
                     FIWNLLSDKSPFDHETDIDVIFFDPDFSYEETLLLEKKLREDFPQYQWELKNQVYMHQ
                     HSPHTASYTSSRDAMSKYPERCTAVGLRLNEESDFELYAPYGLEDILNFQVRPTPHFL
                     ENEDRMELYQTRLSKKNWQEKWKNLIFKNT"
     gene            26138..26896
                     /locus_tag="VQ543_000899"
     CDS             26138..26896
                     /locus_tag="VQ543_000899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000466694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenyl transferase"
                     /protein_id="HET2611641.1"
                     /translation="MFGFFKKDKAVEVEVPTQVPAHIGIIMDGNGRWAKKRMQPRVFG
                     HKAGMEALQTVTKAANKLGVKVITVYAFSTENWTRPDQEVKFIMNLPVEFYDNYVPEL
                     HANNVKIQMIGETDRLPKQTFEALTKAEELTKNNTGLILNFALNYGGRAEITQALKLI
                     SQDVLDAKINPGDITEELIGNYLFTQHLPKDLRDPDLIIRTSGELRLSNFLPWQGAYS
                     ELYFTDTLWPDFDEAALQEAILAYNRRHRRFGGV"
     gene            26905..27708
                     /locus_tag="VQ543_000900"
     CDS             26905..27708
                     /locus_tag="VQ543_000900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidate cytidylyltransferase"
                     /protein_id="HET2611642.1"
                     /translation="MTQDLQKRTLFAGIALAIFLPILMIGGLLLQIAIGIIAMLAMHE
                     LLKMRGLETMTMEGLLTLFATFALTIPLENYLTFLPVDGNVVAYSVLISIMLGTTVFS
                     KSYTIEDAVFPLAMSFYVGFGFNALLDARVAGLDKALLALCIVWATDSGAYLVGMNYG
                     KRKLAPRVSPNKTLEGALGGILGAILVTIIFMIVDSTVALPYGIYKMSVFAIFFSIAG
                     QFGDLLESSIKRHFGVKDSGKFIPGHGGVLDRFDSMLLVFPIMHLFGLF"
     gene            27730..28989
                     /gene="rseP"
                     /locus_tag="VQ543_000901"
     CDS             27730..28989
                     /gene="rseP"
                     /locus_tag="VQ543_000901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000900658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RIP metalloprotease RseP"
                     /protein_id="HET2611643.1"
                     /translation="MLGILTFILVFGIIVVVHEFGHFYFAKKSGILVREFAIGMGPKI
                     FAHIGKDGTAYTIRILPLGGYVRMAGWGDDTTEIKTGTPVSLTLADDGKVKRINLSGK
                     KLDQTALPMQVTQFDFEDKLFIKGLVLEEEKTFAVDHDATVVEADGTEVRIAPLDVQY
                     QNATIWGKLITNFAGPMNNFILGVVVFWVLIFMQGGVRDVDTNQFHIMPQGALAKVGV
                     PETAQITKIGSHEVSNWESLIQAVETETKDKTAPTLDVTISEKGSDKQVTVTPEDSQG
                     RYLLGVQPGVKSDFLSMFVGGFTTAADSALRILSALKNLIFQPDLNKLGGPVAIFKAS
                     SDAAKNGIENILYFLAMISINIGIFNLIPIPALDGGKIVLNILEAIRRKPLKQEIETY
                     VTLAGVVIMVVLMIAVTWNDIMRLFFR"
     gene            29002..30855
                     /locus_tag="VQ543_000902"
     CDS             29002..30855
                     /locus_tag="VQ543_000902"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HET2611644.1"
                     /translation="MKQSKMPIPTLREMPSDAQVISHALMLRAGYVRQVSAGVYSYLP
                     LANRVIEKAKNIMRQEFEKIGAVEMLAPALLSAELWRESGRYETYGEDLYKLKNREKS
                     DFILGPTHEETFTAIVRDSVKSYKQLPLNLYQIQPKYRDEKRPRNGLLRTREFIMKDA
                     YSFHANYDSLDSVYDEYKAAYERIFTRSGLDFKAIIGDGGAMGGKDSQEFMAITSART
                     DLDRWVVLDKSVASFDEIPAEVQEEIKAELLKWIVSGEDTIAYSSESSYAANLEMATN
                     EYKPSNRVVAEEEVTRVATPDVKSIDEVAAFLNVPEEQTIKTLFYIADGELVAALLVG
                     NDQLNEVKLKNHLGADFFDVASEEEVANVVQAGFGSLGPVGLPENIKIIADRKVQDVR
                     NAVVGANEDGYHLTGVNPGRDFTAEYVDIREVREGEISPDGQGVLNFARGIEIGHIFK
                     LGTRYSASMGADVLDENGRAVPIIMGCYGIGVSRLLSAVMEQHARLFVNKTPKGEYRY
                     AWGINFPKELAPFDVHLITVNVKDEEAQALTEKLEASLMGAGYEVLTDDRNERVGVKF
                     SDSDLIGLPIRITVGKKAADGIVEVKIKATGDTIEVHADNVLETLEILSKK"
     gene            30955..32334
                     /gene="bglA"
                     /locus_tag="VQ543_000903"
     CDS             30955..32334
                     /gene="bglA"
                     /locus_tag="VQ543_000903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000943526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HET2611645.1"
                     /translation="MLRFPKDFVWGSSTSGPQTEGRVAGDGKGDNLWDYWFQVEPNRY
                     YNGIGSDKTSTFYENWERDIELLLETGHTVFRTSIQWSRIFPQGCGKVNPQGVDFYRK
                     VFEAIKAKGIRLLVNLYHFDLPFALQEDGDGWENKATVSAYEDYARFCFETYGDLVDQ
                     WITFNEPIVPVEFGYFYDAHYPHKVDAEAAVKVAYHTQLASSRAVKACHELLPDSKIG
                     IVLNLTPAYPRSQHPADVKAARIAALFQAQSFLDPSVLGTYPQELVEILHEHGLLPDA
                     TEEELELIHDNTVDFLGVNYYQPLRVMAPRFAKHPESPLLPEHFYEPYVMPGRKINSH
                     RGWEIYEQGIYDIAQNIKENYGNIEWMLTENGMGVEGEEKFRQDGMIQDDYRIDFVKG
                     HLRELHRAIEDGANCKGYLIWTFIDCWSWLNSYKNRYGLVELDLETQERRLKKSGHWF
                     KKLSDNNGF"
     gene            32526..34334
                     /gene="glmS"
                     /locus_tag="VQ543_000904"
     CDS             32526..34334
                     /gene="glmS"
                     /locus_tag="VQ543_000904"
                     /EC_number="2.6.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014621492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--fructose-6-phosphate transaminase
                     (isomerizing)"
                     /protein_id="HET2611646.1"
                     /translation="MCGIVGVVGNTNATDILIQGLEKLEYRGYDSAGIFVLDGADNHL
                     VKAVGRIAELSAKTAGVEGTTGIGHTRWATHGKPTEDNAHPHRSETERFVLVHNGVIE
                     NYLEIKEEYLAGHHFKGQTDTEIAVHLIGKFAEEDGLSVLEAFKKALHIIRGSYAFAL
                     IDSENPDVIYVAKNKSPLLIGLGEGYNMVCSDAMAMIRETNQYMEIHDQELVIVKADS
                     VEVQDYDGNRRERASYTAELDLSDIGKGTYPYYMLKEIDEQPTVMRKLIQAYTDEAGQ
                     VVVDPDIIKAVQDADRIYILAAGTSYHAGFASKKMLEELTDTPVELGISSEWGYGMPL
                     LSKKPLFIFISQSGETADSRQVLVKANEMGIPSLTVTNVPGSTLSREANYTMLLHAGP
                     EIAVASTKAYTAQIAALAFLAKAVGEANGNAKAQAFDLVHELSIVAQSIESTLSEKET
                     IEAKVRELLETTRNAFYIGRGQDYYVAMEASLKLKEISYIQCEGFAAGELKHGTIALI
                     EEGTPVLALLSDPVLANHTRGNIQEVAARGAKVLTIAEENVAKDTDDIVLTTVHPYLS
                     PISMVVPTQLVAYFATLHRGLDVDKPRNLAKSVTVE"
BASE COUNT        10494 a         5881 c         7579 g        10512 t
ORIGIN      
        1 aaaaagtatt gacaaatttg aaataaagcg tttttcgcac ttgcaaaaat ccgctacaaa
       61 tgttatactg agatagtctg acttataatt gttgtctctg tgtctagagg catcgaatcg
      121 aaatttatgg aggtgctttt gcgtggcaaa agacgatgtg attgaagttg aaggcaaagt
      181 agttgataca atgccgaatg caatgtttac ggttgaactt gaaaatggac atcagatttt
      241 agcaacagtt tctggtaaaa ttcgtaaaaa ctatattcgt attttagcgg gagatcgtgt
      301 tactgtcgaa atgagtccat atgacttgac acgtggacgt atcacttacc gctttaaata
      361 atcgaaaaac ttggagggat aagaaatgaa agtaagacca tcggtcaaac caatttgcga
      421 atactgtaaa gttattcgtc gtaatggtcg tgttatggta atttgcccag caaatccaaa
      481 acacaaacaa cgtcaaggat aagatagaaa ggagaaaaca tggctcgtat tgctggagtt
      541 gatattccaa atgacaaacg cgtagtaatc tcattgactt atgtttatgg tatcggactt
      601 gcaacatcta agaaaatttt ggctgctgct ggaatctcag aagatgttcg tgtacgtgat
      661 cttacatcag atcaagaaga tgctatccgt cgtgaagtgg atgcaatcaa agttgaaggt
      721 gaccttcgtc gtgaagtaaa cttgaacatc aaacgtttga tggaaatcgg ttcataccgt
      781 ggtatccgtc accgtcgtgg acttcctgtc cgtggacaaa atactaaaaa caacgctcgc
      841 actcgtaaag gtaaagctgt tgcgattgct ggtaagaaaa aataatatag gaggtaaaag
      901 tcttggctaa accaacacgt aaacgtcgtg tgaaaaagaa tatcgaatct ggtattgctc
      961 atattcacgc tacatttaat aacactattg ttatgattac tgatgtgcat ggtaatgcaa
     1021 ttgcttggtc atcagctggt gctcttggtt tcaaaggttc tcgtaaatct acaccattcg
     1081 ctgctcaaat ggcttctgaa gctgctgcta aatctgcaca agaacacggt cttaaatcag
     1141 ttgaagttac tgtaaaaggt ccaggttctg gtcgtgagtc agctattcgt gcgcttgctg
     1201 ccgctggtct tgaagtaaca gcaattcgtg atgtgactcc agtgccacac aatggtgctc
     1261 gtcctccaaa acgtcgccgt gtataatcat cgcattacac tgcttttcgt ttaagaggga
     1321 gtaactaaat gatcgagttt gaaaaaccaa atataacaaa aattgatgaa aataaagatt
     1381 atggcaagtt tgtaatcgaa ccacttgaac gtggctacgg tacaactctt ggtaactctc
     1441 ttcgtcgtgt acttctagct tctctaccag gagcagctgt gacatctatc aacattgatg
     1501 gtgtgttaca tgagtttgac acagttccag gtgttcgtga agacgtgatg caaatcattc
     1561 tgaacattaa aggaattgca gtgaaatcgt acgttgaaga cgaaaaaatc atcgaactgg
     1621 atgttgaagg tcctgctgaa gtaacagctg gtgacatttt gacagatagc gatattgaaa
     1681 ttgtaaatcc agatcattat ctctttacaa ttggtgaagg ttcttctcta aaagcgacta
     1741 tgactgttaa cagtggtcgt ggatatgtac ctgctgatga aaataaaaag gataatgcac
     1801 cagttggaac acttgctgta gattctattt atacaccagt tacaaaagtc aactatcaag
     1861 tggaacctgc tcgtgtaggt agcaatgatg gtttcgacaa attaaccctt gaaatcttga
     1921 caaatggaac aattattcca gaagatgctt tagggctttc agcacgtatt ttgacagaac
     1981 atcttgattt gtttacaaat cttactgaga ttgctaagtc aactgaagtg atgaaagaag
     2041 ctgatactga atctgacgac cgtattttag atcgtacgat tgaggaactg gacttgtctg
     2101 tgcgttcata caactgttta aaacgtgccg gtatcaatac tgtgcatgat ttgacagaaa
     2161 aatctgaagc agagatgatg aaagtacgaa atcttggacg caagagtttg gaagaagtga
     2221 aactcaaact cattgatttg ggtcttggat taaaagataa ataaaggagg aatacatggc
     2281 ttaccgtaaa ctaggacgca ctagctcaca acgtaaagca atgcttcgcg atttgacaac
     2341 tgaccttttg atcaacgaat caatcgtgac aactgaagct cgtgctaaag aaatccgtaa
     2401 aactgttgaa aaaatgatta ctctaggtaa acgtggtgat ttgcatgcac gtcgtcaagc
     2461 agctgctttc gtacgtaatg aaatcgcatc tgaaaactat gatgaagcaa ctgataagta
     2521 cacttctact acagcacttc aaaaattgtt ctcagaaatc gcacctcgtt atgctgaacg
     2581 taacggtgga tacactcgta tccttaaaac tgaaccacgt cgtggtgatg cagcgccaat
     2641 ggcgatcatc gaattagtat aaaatcatca attttgttga gtgttatgat gatggagtct
     2701 tgtgctctta gtctagctct ggtctaccgc taggatttcg gtcctagcgg gaacactcat
     2761 cataagttgg gatagtagac gcttgtttac gaaattgttt ttttcttaag aacaacttcg
     2821 taagcaggcg tttttgagta ttttcgttag aattatgcta tactatttga aaagaatcct
     2881 gtttaatgtt aaggtttctt attttaagaa gaattggagt ttacttatga aagccattat
     2941 aactgttgtt ggtaaagata aatctggaat tgttgcaggt gtttctggta aaattgcaga
     3001 attaggattg aatattgacg atatctctca aactgtcttg gatgaatatt ttacgatgat
     3061 ggctgttgta tctagtgatg aaaagcaaga ttttacctat cttcgtaatg aatttgaagc
     3121 ttttgggcaa actttgaatg taaaaatcaa tattcagagt gcagcgattt tcgaagctat
     3181 gtataatatc taggaggtca tcatggatat tagacaagtt actgaaacca tcgccatgat
     3241 tgaggagcaa aacttcgata ttagaaccat taccatgggg atttctcttt tggactgtat
     3301 cgatccagat atcaatcgtg ctgcggagaa aatctatcaa aaaattacga caaaggcggc
     3361 taatttagta gctgttggtg atgaaattgc ggctgagttg ggaattccta tcgttaataa
     3421 gcgtgtatcg gtgacaccta tttctctgat tggggcagcg acagatgcga cggactacgt
     3481 ggttctggca aaagcgcttg ataaggctgc gaaagagatt ggtgtggact ttattggtgg
     3541 tttttctgcc ttagtacaaa aaggttatca aaagggagat gagattctca tcaattccat
     3601 tcctcgcgct ttgactgaga cggataaggt ctgctcgtca gtcaatatcg gctcaaccaa
     3661 gtctggtatt aatatgacgg ctgtggcaga tatgggacga attatcaagg aaacggcaaa
     3721 tctttcagat atgggagcgg ctaagttggt tgtattcgct aatgctgttg aggacaatcc
     3781 atttatggcg ggtgcctttc atggtgttgg ggaagcagat gttatcatca atgtcggagt
     3841 ttctggtcct ggtgtggtga aacgtgcttt ggaaaaagtt cgtggacaga gctttgatgt
     3901 agtagccgaa acagttaaga aaactgcctt taaaatcact cgtatcggtc aattggttgg
     3961 tcaaatggcc agtgagagac tgggtgtgga gtttggtatt gtggacttga gtttggcacc
     4021 aacccctgcg attggagact ctgtggcacg tgtccttgag gaaatggggc tagaaacagt
     4081 tggcacgcat ggaacgacgg ttgccttggc cctcttgaac gaccaagtta aaaagggtgg
     4141 agtgatggcc tgcaaccaag tcggtggttt atctggcgcc tttatccctg tttctgagga
     4201 tgaaggaatg attgctgcag tgcaaaatgg ctctcttaat ttagaaaaac tagaagctat
     4261 gacggctatc tgttctgttg gattggatat gattgccatc ccagaagata cgcctgctga
     4321 aaccattgcg gctatgattg cggatgaagc agcaatcggt gttatcaaca tgaaaacaac
     4381 agctgttcgt atcattccca aaggaagaga aggcgatatg attgagtttg gtggtctatt
     4441 aggaactgca cctgttatga aggttaatgg ggcttcgtct gtcgacttca tctctcgcgg
     4501 tggacaaatc ccagcaccaa ttcatagttt taaaaattaa gaaaatagga gaaattttaa
     4561 gttctattta agattagatg tgtatactat aatcattaaa taaagacctc ctaatattat
     4621 ttgaaacaga taacactgaa ttagtttgaa tttgattttc atctaatatc tttatttaat
     4681 gaactcctaa actttttcat aataatctcc ttcaaaagtc gcctgtatgg gtggctttta
     4741 ttttatcatt catgatataa tagaagcaaa cggaggacgg aaaatggtaa aagtacgatt
     4801 gtatttggta cgtcatggca agaccatgtt taacacgatt ggtcgcgcgc aaggttggag
     4861 cgatactccc ttaactgctg aaggtgaacg agggattcaa gagttaggaa tcggtttgcg
     4921 agaatctgat ctacagtttg agcgcgctta ttcgagtgat tctggtcgta ccattcagac
     4981 catgggaatt atccttgaag aacttggctt gcaggggaaa atcccttatc gcatggacaa
     5041 gcgtatcaga gaatggtgtt tcggtagttt tgatggagcc tatgatggcg atcttttcat
     5101 gggcattatt cctcgtatct ttaatgtgga ccacgttcac caattgtctt atgctgaact
     5161 ggctgagggc ttggtagagg tcgatacagc tggttgggct gaaggctggg aaaaactcag
     5221 tggccgaatc aaggaaggct ttgaaatgat tgcaaaagaa atggaagatc aaggtggagg
     5281 taacgccctt gttgtcagcc atggaatgac tattggaacc attgtttatc tgattaatgg
     5341 catgcatccg catggtctag ataatggtag cgtgacgatt cttgaatatg aggacggtca
     5401 gtttagggtt gaagttgtcg gtgaccgtag ttaccgagag ctaggatgtg agaagatgga
     5461 agaaggctct atttaatcag tctagacttg cttgccatga gctagggatt tgataagaat
     5521 atcaagataa gaaaaaacag ccgagggcac tcctttcggc tgtttttgat gtggaaaact
     5581 aaagtgtaat gctattgctt ttagagattt tcataaacaa gagcaaggaa cctactgtta
     5641 gaacagtcag gatagttgac aaggctgcgg ctacaccgta atttcctctg agaacctctg
     5701 tataaatagc tacagtcatt gttcttgttt tgacattgta gaggaggata gaagtagaga
     5761 gttttgaaat cattgtgacc caagataaga tggctccaga aatgatacca gatagcatca
     5821 ttggagttgt aatcttagca aaggtattga gacgactact tcctaagctt tcagcagctt
     5881 cttcaatact tggtgctatt tgttgtaagc tagcaacaga tgagcgaata gtataaggta
     5941 atcttctgac agatagagac ataatcaaga tgaaagcagt ccctgtaatc ataagaaatc
     6001 cacttccaaa tagaccagta ttgaaggaag aaatgaaggc aatccctaga acggttcctg
     6061 gtacaatata aggtaccata ctgaggctgt caattaagtt tgtaaacaaa ttccgttttc
     6121 taacggctag gtaggagata aatgtcgcaa atagaacaac tagaactaag gcaatcaaag
     6181 ggatacgaat ggtattgaaa atagcagatc ccatacgatt gaaagctacc ttgtaactgt
     6241 ttggagaata acctttaaca gataccatac ctgatgtttt taggaaagag gtataaatta
     6301 agtagatttg aggtaaaaca gagataaaga taattccgta gactgttgca taaatggcag
     6361 ctatttttcc ttttgtagtt tttttaggct caattggatg gagcagattc atgctgaaac
     6421 tgtagcggtt tgcaatgtgt ttttggataa ggaaaattgc caaggcaatg ataatcgcca
     6481 taattgcaaa agcagaattt cctccaacct cgctaataaa ttgggtataa atcaggacag
     6541 ggaaagtccg atatccttcg tcaatcaaca taggcgttcc aaagtctgag aatgctctca
     6601 taaatacaag caaggagctg ctagtaaggt tggaactagg agaggtaaaa caaccgttac
     6661 gatacgctta aatccgaagg accccatgct ttcagctgct tcaagtagag aattgtcaat
     6721 actgttcatt gttccagcaa catatagaaa taccagtggg aatagttgca gtgtaaagac
     6781 aagtacaatt cctttgaatc cataaatatc gatagctgga agatgaaggg catttgtcaa
     6841 aaatttagtg atgacctcat ttcgtcccag caagagaatt caggagtagg ctcctacgaa
     6901 aggagctgac atggaagcaa tgataatcaa tatttgtaga aatttcttcc ccttgaagtc
     6961 atacatagag aagagataag ctaatagggt tcctacaact aaggaagtga tagtagcggt
     7021 aatggaaacc ttgaaactgt tgactagtgt ctcagagtag taggctttac taaagaaagt
     7081 gacaaaatta gctagtgaga attgtccttc atgtataagt gcttgcttga gcacggtaac
     7141 gataggataa acgagaaaga caagataggt aagaaagatg aagaaagagg aagctgtcca
     7201 aatatttagt tttttacatt ccatggttga ctccttttat caggttttgg gaaccatctg
     7261 cagaaaagat gtttaatttt tgcgtattga ttcgtagacg aatacgattg cctttttgta
     7321 gttcttcttc aaaagttgat tcttcactaa cttaaatttt tgaggcaaaa cctgtctcaa
     7381 tgaaatactc cgtatttagt ccaagataga cgctatcgct aatagttcct tcgatatctc
     7441 cagattcatc tttgataaac tcttcgggac gaatgcttac atgaatagct tgctcctcaa
     7501 cctgatcaag agctggcatt cgaagggcat agccatctga aaagacgata taagcgccgt
     7561 cgctccgttt ttcaagattg gcagggataa tatttgtgcg tccgataaag gttgccacaa
     7621 actcattagc tggtttatga tagagttatt ttggtcggcc gatttgttgg atcaccccat
     7681 ctttcataac agcaatttgg tctgaaatag ccatggcttc ttcttggtcg tgggttacat
     7741 aaacagttgt aattcccact tcgtgttgga tttctcggat ggcttgacgc atatccaagc
     7801 gaagtttggc ctccagatta ctaagtggct cgtccatgag gagaacactt ggattaaccg
     7861 ctaaggcgca tgccaaggtg acacgttgtt gttgtccacc actgagttta tcgggctttc
     7921 gatccgcata ttgagcaatt tgcatgagtt caagatactt gttggtctgt tgaatcaatt
     7981 cttcttttgg aaccttcttt tgcataagac caaaagcaac gttgtctcgg acagtcaaat
     8041 gtgggaaaat agcgtagttt tggaaaacca tcccgatatt gcgtttgctg ggttccatat
     8101 tattgatttt tgtatcatcg aagtaaaatt ctccaccttc gatactgttg aaacctgcaa
     8161 tcatacgaag aagggtcgtt ttcccacatc ctgaagctcc aagaagggta aagagacttc
     8221 cttttggaat tgtaatgttc aaattctcaa taacagggac atcgtggtag atttttttgg
     8281 cgttaataat ttcgatctca ctcatagtga acctctttta ctgtttagat tggatatctg
     8341 taaagacttc gttgtatttc ttaacgatat ctgatttatt cttgatgaca taatcataat
     8401 cttcagtgag tgttttgatt ttgtcaattg gtttcatgtt ttcgcttgtt ttagcatttt
     8461 tacgaacagg acggttagta gtggttgtac caagtgtatc ttgtacttct tgagagataa
     8521 taaaatcgat aaatttcttg gcattttcca tatttttaga ttttttaacg atagcagcac
     8581 tagcaggtag gaagacggtt ccttcttttg gatagactac cttaatgtta gctccgtcat
     8641 ttaagagttt aactgctgga tcttcataag agagactaac agtcatttct ccatcagcga
     8701 ctgctttata gacaccagat gaacttaaac cgattttata gtatattgaa actagaatag
     8761 tacacatcta cttctaaaac attgttagaa atcgatttga ctgtcctgat taatttgtcc
     8821 tgttcttatt tcattttact ataccatcaa taagtgtgaa aagatctttt acataagacc
     8881 aagccttatc atctttgtaa ccaccttgag cttgtagcat atttgttaat tgagcaaagg
     8941 cgctagaaga gtttgctggg tcagcagttg cgatttttcc ttttagttca ggtttgagaa
     9001 ggtcgctata tccttcgatg ttcatgcctt tagttaaatc agggtggacg attaaaacac
     9061 taccatctag tgtataagga gtagagaagc cagttgtgtt ttgatattct ttgataacat
     9121 tatcattttc ttttgaaata tagttttcaa agagttctcc gtgggtagca tattgtgtat
     9181 aagaaccacc aaagataata tcagctacag gaacttcttt ttctgactct agttttttga
     9241 aaagttctcc agtaccagct tgaatcagtt ctattttgat accatatttt tcttcaaagg
     9301 caggaatagt tgctccaatt aagccttctg agtttggtga ataaacgact agcgaaccac
     9361 cgtctccttt atcagatgaa ctgtcatcgg cagattcatt agaagaacaa gcagcataat
     9421 acatccattt ctttttcatg atggatacct ccgttgtgtt atttaagttt attttaaaac
     9481 aatgtaagcg tttttaaaac ctacaattct attctatagt gtattgaatc tataacagta
     9541 cacattgact gctaaaatat ttctataaat taatttgact ttcctgatag agatgttcac
     9601 atcttatttc aattcactat attagagtaa aattctctac aaaaaaaaag aatagcctat
     9661 tttactattt ttccgagtga tttcaattcc tttggggaaa tatggagata ctttttaaat
     9721 cctgacaaat ggttgtttct ttttctaaat cggtgatact gtatcggaga atgcgcgtga
     9781 ggtcacaaag gctgcgatag agcttctatg gagaatttct ttttggagag attttttaaa
     9841 ggaatgagac atccgctacc tccttggaag gtttttttgt gataagtata gcagtttaaa
     9901 aattctagag caaggtaaaa tagaaaaggt ttggctaaaa ttttttagct aaaccttttg
     9961 aaaagttaag tatgtattat agatgcttgt tatctgcaaa tagctagagc atttcaagga
    10021 aataaactag aaataacaat taatatggtg gttcagaaat accttttgat aatcaataag
    10081 atcttcagga tgaagtgcgt tgattccatc catttcatat ttccgattta ataaacgata
    10141 tttgttttca ccaaattgat gaaaagggag tagttgaact tggtcgatat ttaatgagtt
    10201 aaatagagta gcgaattttt ctgcatcctc taaactattg ttaaaattag gaataactgg
    10261 gattcttaaa acgatagttt tattttgtga aaaagcataa tgaatgtttt taataatcat
    10321 ttgattaaaa accccagtca cttttttatg ttttatagaa ttataatgtt ttaggtctgt
    10381 gtagataaaa tccacatatt gaattaaatc aataaatttt tcatgatcaa caaaggcagt
    10441 agtttcaatg gcagtgtgta tgtgatgttc tttagctgat tttaagatag ctttagcaaa
    10501 ttcaaactga gcaaatattt cacctcctga taaagttaaa cctccaccgg attcttcgta
    10561 aaattctttg tcttttaata cctctgtaat aatttcttct acagtctttt cttcaccgac
    10621 taaggtgaat ttctctcgtt gagcatcttt cattttttca ggtttcattc tttgagattc
    10681 aggattagaa caccatggac agcgcagagg acatcctttt aaaaaaacag ttgtacgaat
    10741 acccgggccg tcatgaattg aaaagtgttg aatattaaaa ataattcctt tagatatttc
    10801 cataagagtt cctcctcttc ataagtctat cctatcacaa aaacgaaaga aaaacaatta
    10861 cgaacgaaag gttaatttgt tgttttttgc tttttatttt ggtagaataa aacggaggtg
    10921 taaaatgaaa agattggaac aaattattaa attagtatca gaatatgaaa agatcgacgt
    10981 taatacatta tcggaaaaat taaatgtatc gaaagtaacg attagaaaag atttagataa
    11041 attagagtca aaaggtttat tacacagaga gcatggatat gctgtattaa atagtggaga
    11101 tgacttaaat gtacgtttgt caattaatta tgaaattaag agaaaaattg ttcaggaagc
    11161 agtaaaattg gtgtcagata atgaaacgat aatgatagaa tctggatcga cctgtgcttt
    11221 acttgctgag gaaatttgca agcaaaaaag aaatgttacg attgtaacaa attcattttt
    11281 tatagcaaat tttgtgagag cttatgattc atgtcgtatt attgttcttg gtggagagtt
    11341 tcagaaggat tcacaggtta ctgtgggacc tttattaaaa gaaatgatac agacttttca
    11401 tgtgcatcaa gcttttgttg ggacagatgg atacgataaa gagatgggct ttacaggaaa
    11461 agatttaatg cgcagtgagg tagttcaata tatttcagca gcgtcggata aagtcattgt
    11521 cctaactgac tcaagtaaat ttgataaaag gggtacagta agaagatttg ctttaagtca
    11581 agtctatgaa gtaataacag acgaaaaact ttctaaacaa aatatagcta cattagaaaa
    11641 tgctgggata atggttaagg tagtttcgta agaggttaag tgtatgaatc aagataggaa
    11701 taaactgctc tctaaaattg cttatctgta ttatattgaa aacttaaatc agtcacaaat
    11761 agcagcaaaa ttaggaattt atagaacctc tattagtaga atgttaacag aagcaaggaa
    11821 tgcaggaatt gttaaaattg aaatagagaa ttttgatacc aatatgttta agttggaaaa
    11881 ttatgtaaaa gaaaaatatg gtctggaaag tttagaaatt attccaaatg aatttgatga
    11941 taatccaaca attttatctg aaagaatttc tcaagttgca gcaggtgtcc ttaggaatct
    12001 aattgatgat aatatgaaaa ttggcttttc ttgggggaaa agtttaagta atttagtaga
    12061 tttaattcac agtaaaagtg tccgaaatgt tcacttctat cctctagcag gtggtcctag
    12121 tcacatacac gctaaatacc atgtgaatac actgatttat gaaatgtcta gaaaatttca
    12181 tggagagtgt acatttatga atgcaacgat tgtgcaagaa aataaattgt tagcagatgg
    12241 tattttgcaa tcaagatatt ttgaaaattt gaaaaatagt tggaaagatt tagatatagc
    12301 tgtagtcgga attggtgatt ttagcaataa aggaaagcat caatggttag acatgcttac
    12361 agaggatgac tttaaagaat tgaccaaagt taaaactgta ggagaaattt gttgtcgatt
    12421 ttttgattca aaaggtaaag aagtctatga aaacttacag gaaagaacga tagcaatctc
    12481 tttggaagat ttaaaaaata ttcctcaaag tttagctgtt gcttacggtg atacgaaagt
    12541 atcttcgatt ctttctgtct tgcgtgctaa tttagtaaat catttgatta cagacaaaaa
    12601 tacaatttta aaagttttgg aagaagatgg ggatttgact tttagagaga ttctaggtga
    12661 gtgaaaatga tagactgatt cagtttatcg tttttctttt tagttgattg cacatttgtg
    12721 cttatataaa caaaaatagt ttatctgttg tttttggatt gacaacttta ttatgtagtt
    12781 gtattctata gttacaaaag aaaattttaa aatttcaaat gaaaaaagct ttttacatag
    12841 tgaaatgagg aggaatttat ggaaattatt gttccagatc aaattatcat gggtttaatt
    12901 ttatatgctg gtgatgcgaa acaacatatt tataaagcgt tagattacat aaaaaatggt
    12961 acatgtgaac ggtgtgaaga agaaatccag ttagctgatg ccgccttatt agaagcccat
    13021 aatctacaaa caaaattctt ggcacaagaa gcgtctggta caaagacaga aattacagct
    13081 ctctttgttc attcacaaga tcatctcatg actagtatga cggagattaa tttaatcaaa
    13141 gaaattatta gtttgagaaa agaacttcat aaaaaataat actagagtat tatcattgtt
    13201 attaacatag aggaggaaaa cataatggtg aagattggtt tgttttgtgc agcaggtttt
    13261 tctactggta tgcttgtaaa taatatgaaa attgcagcgc aatctagtgg agttgaggca
    13321 gaaatagagg cgttttctca gtctaaatta gcggattatg cgccaaatat agatgttgca
    13381 ctattgggtc cacaagttgc ttatacatta gataaatcaa aagaaatttg tgataagtgt
    13441 gatgttccga tagctgttat tccgatgatg gactatggta tgttagatgg gaaaaaagta
    13501 ttagatttgg ccctatcttt gattagtggg taagaaaagg agatttatta tgtcaaagat
    13561 ggatgttcag aaaatcattg caccgatgat gaagtttgtg aatatgcgtg gcattatagc
    13621 tctaaaagat gggatgttag caattttgcc attgacagta gttggtagtt tgttcttgat
    13681 tatgggacaa ttgccgttcg aaggattaaa taagagcatt gctagtgttt ttggagctaa
    13741 ttggacagag ccgtttatgc aagtatattc aggaactttt gctattatgg gtctaatttc
    13801 ttgtttttca attgcctatt cttatgctaa gaatagcgga gtagaggctt taccagctgg
    13861 agttctatct gtatctgcat tctttatttt gctaagatca tcttatatcc ctaaacaagg
    13921 tgaggcgatt ggggacgcta ttagtaaagt ttggtttgga ggccaaggaa ttatcggtgc
    13981 tatcattata ggtttggtag taggaagtat ttataccttc tttataaaga gaaaaattgt
    14041 tattaagatg ccagaacaag ttccacaagc tattgccaaa cagtttgaag caatgattcc
    14101 agcatttgta attttcttat cttctatgat tgtatatatt ttagcgaagt cattgactaa
    14161 tggcggaaca ttcatagaaa tgatttattc tgctattcaa gttccgttgc aaggtttaac
    14221 tggatctttg tatggtgcta ttggaattgc attctttata tcatttttgt ggtggtttgg
    14281 tgttcatggg caatcggtag taaatggagt agtgacagct ctgcttttat ctaatcttga
    14341 cgctaataaa gctatgttag cctctgctaa tctatcatta gaaaatggtg cacatattgt
    14401 tactcaacaa tttttagatt catttttaat tctatcaggt tcagggatta cgtttggtct
    14461 tgtagttgcc atgctttttg cagcaaaatc aaaacaatac caaaccttag gaaaagttgc
    14521 agcttttcca gcaatattta acgtaaatga gccagttgta tttggatttc cgattgtcat
    14581 gaatccagtt atgtttgtac ctttcattct tgttcctgta cttgcagctg tgatagtata
    14641 tggagctatt gcaacaggtt tcatgcagcc attctcaggg gtaacattgc cttggagtac
    14701 accagctatt ttatcaggat ttttggtggg tggatggcaa ggagttatta ctcagctggt
    14761 gatattagcg atgtctacat tggtttattt tccattcttt aaagtacagg atcgtttagc
    14821 ttaccaaaat gaaatcaaac aatcttagag gtatttgtgt gttactgtta aactcacaca
    14881 tttgtgctaa aaattagaga gttaaaattt ttctagttaa aagcttgaaa atttctataa
    14941 aaatcggtat tatattttcg aaagaaataa aaatattttc gaaagaaagg tggttacgat
    15001 ggtaaataca gaagtagcaa gaacaacaat caagacagaa tattttggca gccttactga
    15061 aaggatgaac aaatatcgag aagatgtttt aaataaaaaa ccttatattg atgctgagag
    15121 agcagttcta gcaacacgcg cctatgaacg atacaaggaa caacctaatg tcctaaaacg
    15181 tgcatatatg ctgaaagaaa ttttggaaaa tatgactatc tatattgaag aagaatctat
    15241 gattgcggga aatcaagctt cttccaataa agatgctcct atttttccgg aatatacgct
    15301 agaatttgtt ctcaatgagt tggatctttt tgaaaagcgt gatggagatg ttttctatat
    15361 tacagaagaa acaaaagaac aacttagaag tattgctccg ttttgggaaa ataataattt
    15421 acgtgctaga gctggtgcct tattacctga agaagtgtct gtttatatgg aaacaggatt
    15481 cttcggtatg gaaggtaaga tgaattctgg agatgctcac ctagcagtta actatcagaa
    15541 acttttgcaa tttggtttaa gaggttttga agagcgggct cgtaaagcaa aagtagctct
    15601 agatttaaca gatccagcaa gtattgataa atatcatttt tacgactcta tatttatcgt
    15661 aatcgatgct attaaagtat atgcaaagcg ctttgttgct cttgctaaaa gtttagccga
    15721 aaatgcaaat cctaaacgta agaaagaatt acttgagatt gcagatattt gctctagagt
    15781 cccatatgaa ccggcaacta cttttgcaga agctattcaa tcagtttggt ttattcaatg
    15841 tattttacaa attgaatcta atggccactc tctttcatat ggccgttttg atcaatatat
    15901 gtatccatat atgaaggctg atttagaaag tggtaaagaa acagaagata gcattgttga
    15961 acgtctgaca aatctttgga ttaagacaat tacaatcaat aaggttcgca gtcaatcaca
    16021 tacattttct tcagcaggaa gtcctttata tcaaaatgtt acaattggtg gacagactcg
    16081 agataagaag gatgctgtta acccattatc ttatttggta ttaaaatcag ttgcacaaac
    16141 ccatctaccg caacctaatc taactgtacg ttaccatgca ggtttagatg ctcgtttcat
    16201 gaatgagtgt attgaagtga tgaaacttgg ttttggtatg cctgcattta ataatgatga
    16261 gattattatt ccttctttta ttgcaaaagg agtattggaa gatgatgctt atgattacag
    16321 tgccattgga tgtgttgaaa cggcagttcc agggaaatgg ggctatcgtt gcacaggtat
    16381 gagttatatg aacttcccta aggttctact tatcacgatg aatgatggaa ttgatccggc
    16441 ttcgggtaaa cggtttgcac caagctttgg tcattttaag gatatgaaga acttttctga
    16501 attagaaaat gcttgggata aaacactaag atatttgaca cgaatgagtg ttattgttga
    16561 aaattctatt gatttatcat tggaacgaga agttcctgat attctatgtt cagcattgac
    16621 tgatgattgt attggtcgtg gaaaacacct taaagaaggt ggagcagtat atgattatat
    16681 atcaggattg caagttggaa ttgcaaattt gtcggattca ttagctgcaa ttaaaaaatt
    16741 ggtgtttgag gaagaacgta taagcccaag tcagctttgg catgcactgg aaacagatta
    16801 tgccggagaa gaaggtaagg tcattcaaga aatgttgatt catgatgcac ctaagtatgg
    16861 taatgatgat gattatgctg acaaattggt tactgctgct tatgacattt atgttgatga
    16921 aattgctaaa tatcctaata cacgttatgg aagagggcct attggaggaa ttcgttattc
    16981 aggaacatct tctatctcag ccaacgtagg gcagggacgt ggaacattag caactccaga
    17041 tggacgcaac gcgggtacac cgttagcaga gggttgttca ccatcacata atatggatca
    17101 acacggccct acatctgttt taaaatctgt ttcaaaatta ccaacagatg aaatcgtagg
    17161 tggggttctc ttaaatcaga aagtaaatcc tcaaacgtta gccaaagaag aagataaatt
    17221 aaaactaatt gctttgttac gaacattctt taatcgttta catgggtacc atattcaata
    17281 caatgttgtt tccagagaga cgttgattga cgctcagaaa catcctgaaa aacacagaga
    17341 cttaattgtt cgtgttgcag gatactctgc attcttcaat gttctttcta aggcaaccca
    17401 agatgacatt ataggacgta ctgagcatac tttgtaaaat aaagaggttc tttttatgga
    17461 atttatgctt gacacattaa atttagatga gattaaaaag tggtctgaaa ttttgccgct
    17521 agctggggta acttcaaatc ccactattgc aaaaagagag ggttctatta atttttttga
    17581 acgaatcaaa gatgtaagag aattgattgg ctctacaccc tctattcatg ttcaggtgat
    17641 ttctcaagat tttgaaggca tcttaaagga tgctcatgaa attcgaagac aagcaggaga
    17701 tgatatattt atcaaagtac ctgttactcc agctggatta cgtgcaataa aggtgctaaa
    17761 aaaagagggc taccatatca ctgcaacagc tatttataca gttattcagg gattattagc
    17821 tatcgaagta ggagcggatt acctagctcc atattataat agaatggaaa atctgaacat
    17881 tgattcaaat tctgtcattc gtcaattagc tcttgctatt gatagacaga actctcctag
    17941 taagatttta gctgcatcct ttaaaaatgt agcacaagta aataatgctt tagctgcagg
    18001 tgcgcatgct gttacagcag gagcagatgt ttttgaatca gctttcgcca tgccatctat
    18061 ccaaaaggcg gttgatgatt tttctgacga ttggtttgtt actcaaaata gtcgttccat
    18121 ttagatagag aggaaataca tatgagaatt tttgctagtc cttctagata tattcagggg
    18181 gaaaatgcct tgtttgaaaa tgccaaatca attttggatt tgggaaatta ccctattcta
    18241 ttatgcgatc agttggttta tgatattgtt ggaaaacgat ttgaagatta tctacatagg
    18301 tatggtttcc atattgttct ggcgctattt aatggtgaag cttctgacaa tgaaatcaat
    18361 cgagttgttg ccttggctga gaaagaaaat tgtgatagta ttatcggtct tggtggggga
    18421 aagacgattg atagcgcaaa agctattgca gatttgattg aaaagcctgt tattattgct
    18481 ccaacaattg catcgaccga cgcacctgta tctgctttat ctgttattta tacagatgaa
    18541 ggtgcatttg atcattatct attttattct aaaaatccag atttagtttt ggttgataca
    18601 aaagttattt cacaagcccc taagcgttta ttagcgtctg gtattgcaga tggtttagca
    18661 acttgggttg aggcgcgtgc ggttatgcag gcaaatggaa aaactatgtt gggacaacag
    18721 caaacattgg ctggagttgc aattgcgaag aaatgtgaag aaacgctgtt tgcagatggt
    18781 ttacaggcta tggcagcttg tgaagctaaa gtggtgacac cagcattaga aaatattgtt
    18841 gaagctaata ctttattgag tggcctaggt tttgaaagtg gaggattagc tgcggcgcat
    18901 gcaattcata atggttttac tgcattgaca ggtgacattc atcatttaac acatggtgaa
    18961 aaagtagctt atggaacttt agtacaacta ttattggaaa atagacctaa agaagaactt
    19021 gataagtata ttgagtttta caaaaaaatt ggtatgccaa caactctaaa agaaatgcat
    19081 ttggatcaag ttggatatga tgatttaata aaagttggta aacaagcaac tatggagggt
    19141 gagacaattc atcagatgcc gtttaagatt tcgccttcag atgttgctca agctattatc
    19201 gctgtagatg cctatgtaaa ttcaaaataa acaataagga ctactgtttt ccaaatggta
    19261 gtcttttatt gatcctcgta ttgaattcta tagcagattg aaataagatg agaacaaatc
    19321 gattgggaaa gtaaaattaa tttctataag tattttagca attgtttcgt actatttcag
    19381 attcagtcca ctatacgttc ttcataaatc aaaaagcgac ataggttgtc ggctatttat
    19441 tgtgaataca ttaattagca ttccagtttt atcttcggtc taaaataagt attttgtgct
    19501 atacgagata agtttcttga cttactcctt gatttactgc ataacaatgg gataaaaagt
    19561 gggagataga gcaattcata gtcatcaaaa ttaatgagat acagtataca gtttttcctt
    19621 taaacacatt tcaaattccc tcaaaaatgg tataatagta acatcacaaa attggagaga
    19681 gaccatgagt ttttacaatc ataaagaaat tgagcctaag tggcagggct actgggcaga
    19741 acatcataca tttaagacag gaacagatgc atcaaaacct aagttttatg cgcttgatat
    19801 gttcccttat ccgtctggag ctggtctgca cgtaggacac ccagaaggtt atactgcaac
    19861 cgatatcctc agtcgttaca aacgtgcgca aggctacaat gtccttcacc caatgggttg
    19921 ggatgctttt ggtttgcctg cagagcaata cgctatggat actggtaatg acccagcaga
    19981 atttacagcg gaaaacattg ccaacttcaa acgtcaaatc aatgcgcttg gattttctta
    20041 tgactgggat cgtgaagtca acacaacaga tccaaactac tacaagtgga ctcaatggat
    20101 tttcaccaag ctttacgaaa aaggcttggc ctatgaagct gaagtgccag taaactgggt
    20161 tgaggaattg ggaactgcca ttgccaatga agaagtgctt cctgacggaa cttctgaacg
    20221 tggaggctat ccagttgtcc gcaaaccaat gcgccaatgg atgctcaaaa tcacggctta
    20281 cgcagagcgc ttgctcaatg acttagatga actagattgg tcagagtcta tcaaggatat
    20341 gcaacgcaac tggattggta aatcaactgg tgccaatgta actttcaaag taaaaggaac
    20401 agacaaggaa tttacagtct ttactactcg tccggacaca cttttcggtg cgactttcac
    20461 tgttttggct cctgaacatg aattagtaga tgccatcaca agcacagagc aagcagaagc
    20521 agtagcagac tacaaacacc aagccagcct taagtcagac ttggctcgta ccgaccttgc
    20581 caaagaaaaa actggtgtat ggactggtgc ttatgccatc aatcctgtca atggtaagga
    20641 aattccaatc tggattgcgg attacgttct tgctagctat ggtacaggtg cggtaatggc
    20701 tgtgcctgcc cacgatcaac gtgactggga atttgccaaa caatttgacc ttccaatcgt
    20761 cgaagtactt gaaggtggaa atgttgaaga agctgcctac acagaagatg gccttcacgt
    20821 taattcagac ttcctagatg gactcaacaa agaagacgct attgccaaga ttgtggcttg
    20881 gttggaagaa aaaggctgtg gacaagagaa ggtaacctac cgtctccgcg actggctctt
    20941 tagccgtcaa cgttactggg gtgagccaat cccaatcatt cattgggaag atggaacttc
    21001 aacagctgtc cctgaaagtg aattgccact tgttttgcct gtaaccaagg atatccgtcc
    21061 ctcaggtact ggtgaaagtc cactagctaa cttgacagac tggcttgaag tgactcgtga
    21121 agatggtgtc aaaggtcgtc gtgaaacaaa tactatgcca caatgggcag gttcaagctg
    21181 gtactacctc cgctatattg acccacacaa tactgagaaa ttggctgacg aggatctgct
    21241 caaacaatgg ttgccagtag atatctacgt gggtggtgcg gaacatgctg tacttcactt
    21301 gctttacgct cgtttctggc ataaattcct ctatgacctc ggtgttgttc caactaagga
    21361 accattccaa aaactcttta accaaggaat gattttggga acaagctatc gtgaccaccg
    21421 tggggctctt gtggcgactg acaaggttga aaaacgtgat ggttctttct tccatgtgga
    21481 aacaggggaa gagttggagc aagcgccagc caagatgtct aaatcgctca agaacgttgt
    21541 caacccagac gatgtggtgg aacaatacgg tgctgatacc cttcgtgtct atgaaatgtt
    21601 catgggacca ctcgatgctt cgattgcttg gtcagaagaa ggtctggaag gaagtcgtaa
    21661 gttccttgac cgtgtttacc gtttgattag aagtaaggaa attgttgcgg aaaacaatgg
    21721 cgctcttgac aaggtttaca acgaaactgt taaagctgtc acagagcaaa ttgattccct
    21781 caaattcaac acagccattg cccaacttat ggtctttgtc aatgcggcta acaaggaaga
    21841 caagctctat gttgactatg ccaaaggatt tatccaattg attgccccat ttgcacctca
    21901 cttggcagaa gaactctggc aaactgttgc tgcaacaggt gagtcaatct cttacgtgac
    21961 ttggccaaca tgggacgaaa gtaaactggt tgaagacgaa atcgaaatcg ttgtccaaat
    22021 caaaggtaaa gtccgtgcca aactcatggt cgctaaagac ctatcacgtg aagaattgca
    22081 agaaattgct ctagcggatg aaaaagtcaa agcagaaatt gacggtaagg aaatcgtgaa
    22141 agtgattagt gtaccaaata aattggttaa tattgttgta aaataaccaa tttatttgct
    22201 gatttccaac ctcaaacagt ttcccaaact gtttgagcca actaaactcg ttaatatcgt
    22261 tgtgaaataa ggtaggaatc cttcagagta gaatctggag gattttttga atcttcttat
    22321 gaaagtatgg tatactatgg gcaactataa agtttgaaaa gtgaaaaaag gagaaagcta
    22381 tgccagtaaa tgaatatggt caaatgattg gggagtcaat ggaaggttat acaccaggtg
    22441 aactgccttc tattgatttc ttagaagggc gttatgctag gatagaggct ctttcagtgg
    22501 aaaagcatgc ggaggatttg ctagctgttt atgggcctga tacgcctcag gagatgtgga
    22561 cctacctttt tcaggagcca gtagcagata tgggggagct ggttagcctt ttacatcaga
    22621 tgttggctcg taaggaccgt ttttactatg caatcataga caaggcgact ggtaaggctt
    22681 tgggatcttt ttctctcatg cgcattgacc agaataaccg agtaatagaa gtcggagcag
    22741 tcactttttc tccagagcta aggggtacac ggataggaac tgaagctcag tatctcctag
    22801 ctcgctatgt ttttgaggag ctaaactatc gtcgctacga gtggaaatgc gatgccttaa
    22861 atctgccatc cagacgagct gcggagcgtt tgagctttat ttatgaagga accttccgtc
    22921 aggcagtggt ttataaggga cgtacgagag atacggattg gttgtctatg attgataagg
    22981 actggcctca agtcaaagat cgtttggaaa catggttgcg tcctgaaaat tttgataaaa
    23041 atggacagca gtacaagagc ttgagagaac tttaagaggt gttgagatga ttactattaa
    23101 aaagcaagaa attgtcaagc tagaggatgt tttacatctc tatcaggctg tcggttggac
    23161 aaattatacc catcaaccag agatgctgga gcaggcctta tctcattcat tagtaattta
    23221 tctggcactt gatggtgatg ctgtggtggg cttgattcgt ttggttggag atggattctc
    23281 atcagtattg gttcaggatt taatcgtttt accaatctat cagcgtcaag gaattggtag
    23341 tgccttgatg aaagaggctt tagaggatta caaagatgcc tatcaagtcc agctggtgac
    23401 agaagagaca gaaagaacct tgggcttcta tcgttctatg ggctttgaaa tcttatccac
    23461 ctataattgt atagggatga cttggatgaa tcgtaaaaaa taacaaaact tgttttttct
    23521 taagcaaaat ttaaggatgg tctagtatta tatagtcatt aaataaagac ctcctaactt
    23581 tatttaataa aatcctaaac ttttcttttt cataataatc tcccttaact ccacccaatc
    23641 aggtggagtt ttttagctct atttcaggct tttggggact attctaaaaa taatttttcg
    23701 atatttttcg gtatttttcg gattttggtc ggggaattgg cggggacttt tttagcgaat
    23761 ataactaaga aataggtctg tggtcgcttc agctagttca aactcaattt gattgtaagt
    23821 gactgttaat tgaagaactg gaactactgt aataatgatt ttgcttgtct agtagtggcg
    23881 tattaaatga gaagtgacat gtaagattgt ctcttcgttt acgaaatcaa aatttctatg
    23941 aaattgatag aatccctaac gttctcttaa tcttaaccgt cttgtcgtac agcggttgaa
    24001 gaaaatgtaa acctttgaca aaattcgtga actatgggat aataaaaagg aattgagtac
    24061 tagttctata tcataggcta gaaaagaccc caagctcacg accaaataag cttgaggtct
    24121 tttttgacac tatttgtcct tgtttagcca tttatcgact atacgaagaa cgacaccgac
    24181 cacaattggt ccgatgatag ttttgagtac taattccatc atgggctatc tcacctcctt
    24241 tcgtaggcgg tgtagcagtg tcgtagaata ttataccaca taagtgctaa acttaggagt
    24301 cacccaatca ggtggctttt ttgtttgtgg cttggttttt tgatataata gagccatgag
    24361 tagaatttta gataatgaga taatggggga tgaggagtta gtagaacgca cgctccgtcc
    24421 tcagtattta cgtgaatata tcggacagga taaggtcaag gaccagctac aaatctttat
    24481 tgaagctgcc aaaatgcggg atgaagcgct ggatcatgtg ctcttatttg ggcctccagg
    24541 tctcgggaaa acgaccatgg cctttgttat tgccaacgaa ctgggagtca atcttaagca
    24601 gacgtcgggt ccagtcattg aaaaagccgg agatctggta gctattttga atgagttaga
    24661 gcctggggat gtacttttta ttgatgagat ccatcgtttg ccaatgtcag tggaagaggt
    24721 gctttatagt gctatggagg acttctacat agatattatg attggggctg gtgagggtag
    24781 tcgtagtgtt catttggagt taccaccttt taccttgatt ggtgcgacga ctcgggctgg
    24841 tatgctctcc aatccgctac gggcacgttt tgggattaca ggccatatgg agtattatgc
    24901 ccatgctgac ttgacagaaa ttgtcgagcg gacggcagat atttttgaga tggaaatcac
    24961 tcatgaggca gcatctgagt tggccctacg tagtcgtggg acccctcgta ttgccaatcg
    25021 tctcctcaag cgcgtgcgcg attttgccca gataatgggg aatggggtaa ttgatgatat
    25081 tattaccgat aaggctttga ctatgctgga tgttgaccat gaaggtttgg actatgtgga
    25141 tcaaaaaatc cttcgtacca tgattgagat gtacagtgga ggacctgttg gtctaggaac
    25201 tctttctgtg aatatcgccg aagagcgtga gacagttgaa gatatgtatg agccttactt
    25261 gattcaaaaa ggttttatca tgcggacacg gtctggacgg gtggcgactg ctaaggcata
    25321 tgagcactta ggttatgaat acagtgaaaa ataagcaaga aatcttagag gcttttagag
    25381 aaaatccaga tatgatggcc attctgacga tcatccgaga ccttggtctg aaagactcgt
    25441 ggttggcagc aggttctgtc agaaatttca tttggaatct tttgtcagac aaatcccctt
    25501 ttgatcatga aacagatata gatgtgattt tctttgatcc agatttttct tatgaggaaa
    25561 ccttattact ggagaaaaag ctgagagagg attttcctca gtaccagtgg gaattgaaaa
    25621 atcaggtcta tatgcatcag cacagtcctc acactgcttc ctataccagt tctcgtgatg
    25681 ctatgagtaa gtatccagaa cggtgtacgg cagttggact gcgcttgaat gaagaatcag
    25741 attttgaact ctatgcacct tatggtttgg aggatatttt gaattttcaa gttcgtccaa
    25801 ctcctcattt cttagaaaat gaagaccgaa tggaactcta tcaaacacgt ttatccaaga
    25861 aaaattggca ggagaaatgg aaaaatttga tttttaaaaa tacttaagga aactttaagc
    25921 tagggagtgt acactaagtt cataagttaa gaagacctta acttaaactc ctaaaacttt
    25981 ttcataataa tctccctata aaaataaagt cgcccaatca ggcggcttat ttttttgaaa
    26041 aatgggcatg gtgcctgaga ataaatagct tagtgataga agaaaatggg gaaatatggt
    26101 ataatgaaac gatagatttt tgaataggaa taagatcatg tttggatttt ttaagaaaga
    26161 taaggctgtg gaagtagagg ttccgacaca ggttcctgct catatcggca tcatcatgga
    26221 tggcaatggc cgttgggcta aaaaacgtat gcaaccgcga gtttttggac ataaggcggg
    26281 catggaagca ttgcaaaccg tgaccaaggc agccaacaaa ctgggcgtca aggttattac
    26341 ggtctatgct ttttctacgg aaaactggac ccgtccagat caggaagtca agtttatcat
    26401 gaacttgcca gtagagtttt atgataatta tgtcccggaa ctacatgcga ataatgttaa
    26461 gattcaaatg attggggaga cagaccgcct gcctaagcaa acctttgaag ctttaaccaa
    26521 ggctgaggaa ttgactaaga acaacacagg attgattctt aattttgctc ttaactatgg
    26581 tggacgtgct gagattacac aggcgcttaa gttgatttcc caggatgttt tagatgccaa
    26641 aatcaaccca ggtgacatca cagaggaatt gattggtaac tatctcttta ctcagcattt
    26701 gcctaaggac ttacgagacc cagacttgat tatccgtact agtggagaat tacgtttgag
    26761 caattttctt ccatggcagg gagcctatag tgagctttat tttacggaca ccttatggcc
    26821 tgattttgac gaagcggcct tgcaggaagc tattcttgcc tataatcgtc gtcatcgccg
    26881 atttggagga gtttaggagg aaatatgacc caggatttac agaaaagaac cttgtttgca
    26941 gggattgccc tggctatttt cctaccaatt ttaatgattg ggggcctctt gcttcagata
    27001 gcaatcggaa tcatagccat gctagccatg catgaacttt tgaagatgag aggtctagag
    27061 accatgacga tggagggcct cttgaccctc tttgcaacct ttgcattgac cattcccttg
    27121 gagaattacc tgactttttt gccagttgat gggaatgtgg ttgcctatag tgttttgatt
    27181 tcaatcatgt taggaacgac cgtttttagc aagtcttata cgattgagga tgcggttttc
    27241 cctcttgcta tgagcttcta cgtgggcttt ggatttaatg ctttactaga tgctcgtgtt
    27301 gcaggtttgg acaaggctct cttagccttg tgtatcgtct gggcgacaga cagtggtgcc
    27361 tatcttgttg ggatgaacta tgggaaacga aagttagcac caagggtatc gcctaataaa
    27421 acccttgagg gtgccttggg tggtatttta ggagcaattt tagtaaccat tatctttatg
    27481 atagttgaca gtacagttgc tcttccatat ggaatttaca agatgtcagt ctttgctatt
    27541 ttctttagca ttgctggaca atttggtgat ttactagaaa gttcgatcaa acgtcatttt
    27601 ggtgttaagg attctgggaa atttatccct ggacatggtg gtgttttgga tcgtttcgat
    27661 agtatgttgc ttgtatttcc aatcatgcac ttatttggac tcttttaatc aaaagacgga
    27721 ggaaacgcta tgctcggaat tttaaccttt attctggttt tcgggattat tgtagtggtg
    27781 cacgagttcg ggcacttcta ctttgccaag aaatcaggga ttttagtacg tgaatttgcc
    27841 atcggtatgg gacctaaaat ttttgctcac attggcaagg atggaacggc ctataccatt
    27901 cgaatcttgc ctctgggtgg ctatgtccgc atggccggtt ggggtgatga tacaactgaa
    27961 atcaagacag gaacgcctgt tagtttgaca cttgctgatg atggtaaggt taaacgcatc
    28021 aatctctcag gtaaaaaatt ggatcaaaca gccctcccta tgcaggtgac ccagtttgat
    28081 tttgaagaca agctctttat caaaggattg gttctggaag aagaaaaaac atttgcagtg
    28141 gatcacgatg caacggttgt ggaagcagat ggtactgagg ttcggattgc acctttagat
    28201 gttcaatatc aaaatgcgac tatctggggc aaactgatta ccaattttgc aggtcctatg
    28261 aacaatttta tcttaggtgt cgttgttttt tgggttttaa tctttatgca gggtggtgtc
    28321 agagatgttg ataccaatca gttccatatc atgccccaag gtgccttggc caaggtagga
    28381 gtaccagaaa cggcacaaat taccaagatt ggctcacatg aggttagcaa ctgggaaagc
    28441 ttgatccaag ctgtggaaac agaaaccaaa gataagacgg caccgacttt ggatgtgact
    28501 atttctgaaa aggggagtga caaacaagtc actgttacac ccgaagatag tcaaggtcgt
    28561 taccttctag gtgttcaacc gggggttaag tcagattttc tatccatgtt tgtaggtggt
    28621 tttacaactg ctgctgactc agctctccga attctctcag ctctgaaaaa tctgattttc
    28681 caaccggatt tgaacaagtt gggtggacct gttgctatct ttaaggcaag tagtgatgct
    28741 gctaaaaatg gaattgaaaa tatcttgtac ttcttggcaa tgatttccat caatattggg
    28801 atttttaatc ttattccgat tccagccttg gatggtggta agattgtgct caatatccta
    28861 gaagccatcc gccgcaaacc attgaaacaa gaaattgaaa cctatgtcac cttggccgga
    28921 gtggtcatca tggttgtctt gatgattgct gtgacttgga atgacattat gcgactcttt
    28981 tttagataat cgaggaatat tatgaaacaa agtaaaatgc ctatcccaac gcttcgcgaa
    29041 atgccaagcg atgctcaagt tatcagccat gctcttatgt tgcgtgctgg ttatgttcgc
    29101 caagtttcag caggtgttta ttcttatcta ccacttgcca atcgtgtgat tgaaaaagct
    29161 aaaaacatca tgcgccaaga attcgaaaag attggtgctg ttgagatgtt ggctccagcc
    29221 cttcttagtg cagaattgtg gcgtgaatca ggtcgttacg aaacctatgg tgaagacctt
    29281 tacaaactaa aaaaccgtga aaaatcagac tttatcttag gtccaactca cgaagaaacc
    29341 tttacagcta ttgtccgtga ttctgttaaa tcttacaagc aattgccact caacctttat
    29401 caaattcagc ccaagtatcg tgatgaaaaa cgcccacgta atggacttct tcgtacacgt
    29461 gagtttatca tgaaggatgc ttatagtttc cacgctaact atgatagttt ggatagtgtt
    29521 tatgatgagt acaaagcagc ctatgagcgt attttcactc gtagtggttt agacttcaag
    29581 gctattattg gtgacggtgg agccatgggt ggtaaggata gccaagaatt tatggccatt
    29641 acatctgctc gtacagacct tgaccgctgg gttgtcttgg acaagtcagt tgcctcattt
    29701 gacgaaattc ctgcagaagt gcaagaagaa atcaaggcag aattgctcaa atggatagtc
    29761 tctggtgaag ataccattgc ttactcaagt gagtctagct atgcagctaa cttagaaatg
    29821 gcaacaaacg agtacaaacc aagcaaccgt gttgtcgctg aagaagaagt tactcgtgtt
    29881 gcaacgccag atgttaaatc aattgatgaa gttgcagctt tcctcaatgt tccagaagaa
    29941 caaacgatta aaaccctctt ctacattgca gatggtgagc ttgttgcagc ccttctagtt
    30001 ggaaatgacc aactcaacga agtcaagttg aaaaaccact taggagcaga tttctttgac
    30061 gttgctagcg aagaagaagt ggcgaatgtt gttcaagcag gatttggttc acttggacca
    30121 gttggtttgc cagagaatat taaaattatt gcagatcgta aggtgcaaga tgttcgcaat
    30181 gcagttgtcg gtgctaacga agatggctac cacttgactg gtgtgaaccc aggccgtgat
    30241 tttactgcag aatatgtgga tatccgtgaa gttcgtgagg gtgaaatttc cccagatgga
    30301 caaggtgtcc ttaactttgc gcgtggtatt gagatcggtc atattttcaa actcggaact
    30361 cgctactcag caagcatggg agcagatgtc ttggatgaaa atggtcgtgc tgtgccaatc
    30421 atcatgggat gttacggtat cggtgtcagc cgtcttcttt cagcagtgat ggagcaacac
    30481 gctcgcctct ttgttaacaa aacgccaaaa ggtgaatacc gttacgcttg gggaatcaat
    30541 ttccctaaag aattggcacc atttgatgtg catttgatta ctgtcaatgt caaggatgaa
    30601 gaagcgcaag ccttgacaga aaaacttgaa gcaagcttga tgggagctgg ttatgaagtc
    30661 ttgacagatg accgtaacga acgtgtcggt gttaaattta gcgatagtga cttgattggt
    30721 cttccaatcc gtatcactgt tggtaaaaaa gcggccgatg gcattgtaga agttaagatc
    30781 aaggcaactg gtgacaccat tgaggttcat gcagataacg tgcttgaaac gcttgaaatc
    30841 ctaagcaaga aataaaaact ataatcagaa gaaaaacaag gaaaaaatgt aactagtttt
    30901 taccttgttt tttctgtata atgggagaaa tgagtagata aagaggtaaa tgttatgcta
    30961 agatttccaa aggattttgt ctggggatcc tctacttctg gaccgcagac agaaggacgt
    31021 gtagctggtg acggtaaggg agacaatctc tgggattact ggttccaagt ggagccaaat
    31081 cgttactata atgggattgg ttcagataag acatcgactt tttatgaaaa ttgggagcgg
    31141 gatattgagc ttttgttaga gactggtcac acagtctttc ggacttctat tcagtggtca
    31201 cggatttttc cacaaggctg tggaaaagtc aaccctcaag gtgtggattt ttatcgtaag
    31261 gtctttgagg ctattaaggc taaaggaatt cgtctgttag tcaatctcta tcattttgat
    31321 ttaccttttg cccttcaaga ggatggtgat ggttgggaaa ataaggcgac agtctcagcc
    31381 tatgaagact atgctcgttt ttgttttgag acttatggag atttagtgga tcaatggatt
    31441 acctttaacg agcccatcgt tcctgtagaa tttggttatt tttatgatgc ccattatcca
    31501 cataaggtgg atgcagaggc agctgttaag gtagcctatc atacacaatt ggccagcagc
    31561 cgggctgtta aggcttgcca tgaacttttg cctgattcca agattgggat tgtcctcaac
    31621 ttgacaccgg cttatccacg tagccagcat cctgctgatg tcaaggcagc tcgtattgcg
    31681 gccctttttc aggcccaatc tttcttagat ccatctgtct tggggactta tccacaggag
    31741 ttggtagaaa tcttgcatga acacggtctt ttacctgatg ctacagagga agagttggaa
    31801 ctcattcatg ataatacggt ggacttcctt ggtgtgaact actatcaacc tttgcgtgtt
    31861 atggctcctc gatttgctaa gcatccagag agtccactct taccagaaca tttttacgag
    31921 ccttatgtga tgcctggacg taaaatcaat tctcaccgtg gttgggagat ttatgagcaa
    31981 gggatttatg acatcgccca aaatatcaag gaaaattatg gcaatattga atggatgttg
    32041 actgagaatg gtatgggtgt tgaaggggaa gaaaaattcc gtcaagatgg aatgattcaa
    32101 gatgattacc gtattgactt tgtaaaaggt catcttcgtg aacttcaccg tgccattgaa
    32161 gatggtgcca actgtaaggg ctacttgatt tggaccttta ttgactgctg gtcatggctc
    32221 aacagctata aaaatcgcta tggtttggtc gaattagact tggaaacgca agaacgtcgt
    32281 ctgaagaaat caggccactg gttcaaaaaa ttaagcgata ataatggatt ttaaaaagga
    32341 ctctgactga ttatcccaat cggtcagagt tttttgctta caggagctta atttgaacta
    32401 taccaatttt tactcttgac aagtgaaaga aacaagtata tactgttttt gctgattcta
    32461 taaaagatga attagactat accaatttta aggagaaagc acagcttgcc tgtgtcgtat
    32521 atactatgtg tggaattgtt ggtgttgttg gaaacacaaa tgcaactgat attttgattc
    32581 aagggcttga aaagcttgaa taccgtggct atgattctgc gggaattttt gtcctagatg
    32641 gtgctgataa ccatttggtg aaggctgttg gtcgtatcgc agaattgtct gccaagacag
    32701 ctggtgttga gggaacaact ggtatcggac atactcgttg ggcaactcat gggaaaccaa
    32761 cggaagacaa tgctcaccca caccgctctg agacagaacg ttttgtcttg gttcacaatg
    32821 gggtgattga aaactacctt gaaattaaag aagaatacct tgctgggcac cacttcaaag
    32881 ggcaaacaga tacggaaatc gccgtacatt tgattggaaa atttgcggaa gaagacggtc
    32941 tctcagttct tgaagccttt aaaaaagctc ttcatattat ccgtggttca tatgcctttg
    33001 ccttgattga ctctgaaaat ccagatgtca tctatgtagc gaaaaacaaa tctccacttt
    33061 tgattggtct tggggaaggc tacaatatgg tctgctcaga tgctatggct atgattcgtg
    33121 aaaccaacca atacatggaa attcatgacc aagagttggt aatcgtcaag gctgatagcg
    33181 tggaagttca agactatgat ggaaatcgtc gtgagcgtgc tagctacact gctgaacttg
    33241 acttgtcaga tatcggtaag ggaacttacc cttactacat gctcaaggaa attgacgagc
    33301 aaccaactgt tatgcggaaa ctcatccaag cctacacaga tgaggctggt caagttgtcg
    33361 tagacccaga tatcattaag gctgttcaag acgcagaccg catctacatc cttgcagctg
    33421 gaacatctta ccatgcagga tttgcttcta agaagatgtt ggaagaattg acagatacac
    33481 cagttgaact tggaatctca tctgagtggg gctacggtat gccacttctc agcaagaaac
    33541 cactcttcat ctttatcagc caatctggtg aaacagcgga tagtcgtcaa gttttggtca
    33601 aggctaatga aatgggaatt ccaagcttaa cagtgacaaa tgttccaggt tcaaccctct
    33661 cacgtgaagc caactatacc atgctccttc acgcaggtcc tgaaattgcc gtggcatcaa
    33721 ctaaagccta tacagcgcaa atcgcagccc ttgccttcct tgcaaaagca gtcggagaag
    33781 caaatggtaa tgctaaagcg caagcctttg acctggttca tgaattgtca atcgtagctc
    33841 agtctattga atcaactctt tcagagaaag aaaccattga agccaaggtt cgtgaacttc
    33901 ttgaaacaac tcgtaacgcc ttttacatcg gacgtggtca agattattac gtagccatgg
    33961 aagcaagtct caaactcaaa gagatttctt atatccagtg tgaaggtttt gcggcaggag
    34021 aactcaagca cggaaccatt gccttgattg aagaaggaac gcctgttttg gctctcttgt
    34081 cagatccagt tcttgccaac catactcgtg gaaatatcca agaggtcgca gcccgtggtg
    34141 ccaaagtcct cactatcgca gaagagaatg tagccaaaga taccgacgat atcgtcctta
    34201 cgaccgtaca tccatacctc tcaccaattt caatggtcgt accaacgcaa ttagtcgctt
    34261 actttgcaac cctccaccgt ggcctcgatg tggacaaacc acgtaacctt gccaagtcag
    34321 taacggtaga ataagctaaa aaagtctagt tatctaggct ttttcttgtg agcaaattgg
    34381 ttgcttgtac tcaagattcg tgttatactc ttagaaaatc tcttcaaacc acgtcaccgt
    34441 cgccttgccg taggtatggt tactga
//
LOCUS       DAVBEO010000018        34347 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 009
            SAMEA1678075-rid20185393.denovo.018, whole genome shotgun sequence.
ACCESSION   DAVBEO010000018 DAVBEO010000000
VERSION     DAVBEO010000018.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678075
            Sequence Read Archive: ERR226392
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 34347)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34347)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980207.1
            Genome Coverage       :: 150x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:50:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 72 of 147
            Pseudo Genes (incomplete)         :: 72 of 147
            Pseudo Genes (internal stop)      :: 42 of 147
            Pseudo Genes (multiple problems)  :: 32 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34347
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678075-rid20185393.denovo.018"
                     /strain="KS 009"
                     /db_xref="taxon:1313"
     gene            <1..4786
                     /locus_tag="VQ543_000905"
     CDS             <1..4786
                     /locus_tag="VQ543_000905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000682812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HET2611647.1"
                     /translation="QGERGLTGAKGEKGDQGERGLTGAQGEKGDRGERGLTGAKGEKG
                     AQGQAGRDGVTPTVTVKDNKNDGTHTITINDGRGNVTSTVVRDGFDGASPLVATQRND
                     ADKTTTVIFYYDKNGNNELDASDKKLKEVVIADGAKGEKGDKGEQGLQGRDGEQGPKG
                     EDGKTPTVKVTDGQDGTHTITINDGKGGITTTVVRDGFDGASPLVSTHRNEADKTTTV
                     IFYYDLNDNNQFDEGDTKLKEVVIADGKQGPKGDKGDNGKDGFTPEVTVTDNNNGTHT
                     ITITQPDNRPSLTTIVKNGEDGKTPKVKAERDDAKKQTTLTFYIDKDGDGSYTAGKDE
                     LVQTTVVKDGQDGAAGASGRDGKEVLNGKVDPTTEGKDGDTFVNTQTGDVFVKKGNTW
                     EPAGNIKGPKGDKGADGAKGEKGAQGERGLTGAQGVKGEKGDQGERGLTGSKGEKGDQ
                     GERGLTGAQGAKGDKGEQGLQGRDGAQGPKGADGQRGPAGPQGPKGEQGNPGTPGKDG
                     KSLIAVKNGTETKVYVEDPARPGQPLNPNQPLATITDGRNGTNGQSPTITATRSVQNG
                     KNGVLVTITPVGGRPQTTFVEDGQKGADGKTPTVTITEGQNGTHTLTVHNPGSPDVTT
                     TIRDGATGQAGRDGKDVLNGKVNPQPNQGKNGDKYINTETGDVYVKNNGNWDKEGNIK
                     GPKGDKGADGAKGEKGDQGERGLTGAQGAKGADGAVGRDGRDGKDVLNGKANPEAHQG
                     KDGDKYVNTETGDVFVKNNGNWDKEGNIKGPKGDKGERGEDGKTPEVTVTPGKDGHST
                     DITFTVPGKDPVTVNVKDGENGLNGKTPKVDLLRVQGKNGNPSHTIVTFYTDENNDGK
                     YTPGTDELLGSEMIKDGAKGADGRDGKSLLTVKDGKETKVYQEDPANPGQPLNPEKPL
                     AVIRDGVDGKSPTVTAVRKDEAGHKGVEITVDNHDGSQPTTVFVQDGAKGETGATGQD
                     GQTPTITTQRGQDGQSTVVTITTSGKDPVTFTVKDGKNGKDGRAPKIKVEDITSPSRI
                     RRDTDAAATPTRNGIRVTVYDDVNDNGVYDEGVDKVLNSKDIYNGIDGRDGSAPTITT
                     KDNGDGTHTITVQNPDGSESTTVVKDGKDGKTANITTTENPDGSHTITVTNPDGSTKE
                     TVVKNGKDGKTPKVEVTDNNDGTHTVKVTDGDGNVTNAIIKDGKDGKAATATTTENPD
                     GSHTVTITNPDGTKNEFVVKNGRDGVDGRTPTASVRDNGDGSHTIVITNPEGVTTETT
                     VRDGKSPKVTITDEQNGTHKISVLNGDGTTTTTTVRDGREPKLEVIDNNDGSHTIKVT
                     GADGKGTTTTIFDGKSPKANIVDNGDGTHTLTIVDSDGREYKSIIKDGKDGKDSVSPT
                     VTVKNNNDGTHVVTITNPDGSKTEMVIKDGKDGKSPKVSVEDNGDGSHTITIINSDGT
                     VTKTVIKDGRDGRDGRDGKDGKDGKDGKCGCQDKPVTPSNDKPVPPTPNVPTPEVPVK
                     PVPAQPTPNVPTPEVPVQPTPAVPTPEVPVKPVPAVPEQPVVPTPAQPATPVNANPVA
                     PTTGKENRGDKLPETGSQSDYISVLLGSGILLSLYVGRRKEA"
     gene            complement(5023..5571)
                     /locus_tag="VQ543_000906"
     CDS             complement(5023..5571)
                     /locus_tag="VQ543_000906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000039625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HET2611648.1"
                     /translation="MSKKVLFIVGSLRQGSFNHQMALEAEKALAGKAEVSYLDYSALP
                     LFSQDLEVPTHPAVAAAREAVLVADAIWIFSPVYNFSIPGTVKNLLDWLSRALDLSDT
                     RGVSALQDKFVTVSSVANAGHDQLFAIYKDLLPFIRTQGVGDFTAARVNDSAWADGKL
                     VLEETVLNSLEKQAQDLVEAIQ"
     gene            5892..6380
                     /locus_tag="VQ543_000907"
     CDS             5892..6380
                     /locus_tag="VQ543_000907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5590 domain-containing protein"
                     /protein_id="HET2611649.1"
                     /translation="MKKRQNKAKNNLLWQYGLGMTILFVVISASFLYMVSLSMKPYQT
                     AKSEGEKLAQQYAGLEQADQVDLYNGLESYYSVLGRNKQQEALAVLIGKDDHKIYVYQ
                     LNQGVSQEKAETVSKEKGAGEIDKIIFGRYQDKPIWEVKSGSDFYLVDFETGALVNKE
                     GL"
     gene            6377..7564
                     /locus_tag="VQ543_000908"
     CDS             6377..7564
                     /locus_tag="VQ543_000908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HET2611650.1"
                     /translation="MKLSNRVLEMEESVTLAAGARAKALKAEGRDILSLTLGEPDFTT
                     PKNIQDAAIASIRDGRASFYTVTSGLPELKAAVNSYFERFYGYSVASNQVTVAAGAKY
                     SLYTFFMAVVNPGDEVIIPTPYWVSYGDQVKMAEGVPVFVSAKEDNHFKVTVEQLEAA
                     RTDKTKVLVLNSPSNPTGMIYTREELLAIGNWAVENDILILADDIYGRLVYNGHEFTP
                     ISSLSEAIRKQTVVINGVSKTYAMTGWRIGYAVGEADIIAAMSKIAGQTTSNPSAVAQ
                     YAAVEALSGEQDTVESMRQAFEERLNTIYPLLAEVPGFEVVKPQGAFYLFPNVKKAME
                     MKGYTDVTDFTTVILEEAEVALVTGAGFGAPENVRLSYATDLDTLKEAVERLKAFMGS
                     END"
     gene            7557..7922
                     /locus_tag="VQ543_000909"
     CDS             7557..7922
                     /locus_tag="VQ543_000909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HET2611651.1"
                     /translation="MIDHFEIKVKDLQISEGFYRSFLAPLDYKLAFKTSSLISFLSPN
                     SPHPGGDFWLTQGTQDPVHFAFLAENKEEVQACYEAGLEAGGRDNGAPGYRSEHPIYY
                     AAFMIDLDGNNIEVVCHKE"
     gene            7938..9284
                     /gene="asnS"
                     /locus_tag="VQ543_000910"
     CDS             7938..9284
                     /gene="asnS"
                     /locus_tag="VQ543_000910"
                     /EC_number="6.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine--tRNA ligase"
                     /protein_id="HET2611652.1"
                     /translation="MMTKRVTIIDVKDYVGQEVTIGAWVANKSGKGKIAFLQLRDGTA
                     FFQGVAFKPNFVEKFGEEVGLEKFDVIKRLSQETSVYVTGIVKEDERSKFGYELDITD
                     IEVIGESQDYPITPKEHGTDFLMDNRHLWLRSRKQVAVLQIRNAIIYATYEFFDKNGF
                     MKFDSPILSGNAAEDSTELFETDYFGTPAYLSQSGQLYLEAGAMALGRVFDFGPVFRA
                     EKSKTRRHLTEFWMMDAEYSYLTHDESLDLQEAYVKALLQGVLDRAPQALETLERDTE
                     LLKRYIAEPFKRITYDQAIDLLQEHENDEDADYEHLEHGDDFGSPHETWISNHFGVPT
                     FVMNYPAAIKAFYMKPVPGNPERVLCADLLAPEGYGEIIGGSMREEDYDALVAKMDEL
                     GMDRTEYEFYLDLRKYGTVPHGGFGIGIERMVTFAAGTKHIREAIPFPRMLHRIKP"
     gene            9437..9727
                     /locus_tag="VQ543_000911"
     CDS             9437..9727
                     /locus_tag="VQ543_000911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018030687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S6"
                     /protein_id="HET2611653.1"
                     /translation="MAKYEILYIIRPNIEEEAKNALVARFDSILTDNGATVVESKTWE
                     KRRLAYEIQDFREGLYHIVNVEANDDAALKEFDRLSKINADILRHMIVKIDA"
     gene            9739..10209
                     /gene="ssbA"
                     /locus_tag="VQ543_000912"
     CDS             9739..10209
                     /gene="ssbA"
                     /locus_tag="VQ543_000912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein SsbA"
                     /protein_id="HET2611654.1"
                     /translation="MINNVVLVGRMTRDAELRYTPSNVAVATFTLAVNRTFKSQNGER
                     EADFINVVMWRQQAENLANWAKKGSLIGVTGRIQTRSYDNQQGQRVYVTEVVAENFQM
                     LESRSVREGHTGGAYSAPTANYSAPTNSVPDFSRNENPFGATNPLDISDDDLPF"
     gene            10241..10480
                     /locus_tag="VQ543_000913"
     CDS             10241..10480
                     /locus_tag="VQ543_000913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S18"
                     /protein_id="HET2611655.1"
                     /translation="MAQQRRGGFKRRKKVDYIAANKIEYVDYKDTELLSRFVSERGKI
                     LPRRVTGTSAKNQRKVTTAIKRARVMALMPFVNED"
     gene            10775..12175
                     /locus_tag="VQ543_000914"
     CDS             10775..12175
                     /locus_tag="VQ543_000914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional Cof-type HAD-IIB family
                     hydrolase/peptidylprolyl isomerase"
                     /protein_id="HET2611656.1"
                     /translation="MDAKLRYKAKKIKIVFFDIDDTLRNSKTGFIPTTIPTVFKQLRE
                     KGILTGIASGRGIFGVVPEIRDLKPDFFVTLNGAYIEDKKGQVIYQHQIEKSYVEEYI
                     SWAKQEGIEYGLVGSHDAKLSTRTDMMSEAINPIYPDLDVDPDFHEKEDIYQMWTFED
                     KGDDLHLPDSLSDKLRMVRWHQHSSDIVPISGSKATGVEKVVEHLGLKPEKVMVFGDG
                     LNDLELFDYAGISVAMGISHDKIKEKADYITKTLEEDGIFDALEVFGMVEKELHFPQV
                     DIETVEGPLATIKTNHGDLRIKLFPEHAPKTVANFVSLSKDGYYDGVIFHRIIKDFMI
                     QGGDPTGTGMGGESIYGESFEDEFSEELYNIRGALSMANAGPNTNGSQFFIVQNQHLP
                     YSKKEITRGGWPEPIAEIYANQGGTPHLDRRHTVFGQLADEASYAVLDVIAAVETGAM
                     DKPVEDVVIETIEIED"
     gene            12177..12536
                     /locus_tag="VQ543_000915"
     CDS             12177..12536
                     /locus_tag="VQ543_000915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000689596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S1 RNA-binding domain-containing protein"
                     /protein_id="HET2611657.1"
                     /translation="MKIGDKLKGRITGIQPYGAFVELETGDTGLIHISEIRTGFIENI
                     HETLKVDEEVQVQVVDLDEFTGKASLSIRTLEEEKYQFPRRRRFSSDRFNYGFAPFRR
                     MLPIWTGEALHHLKKKK"
     gene            12590..13339
                     /locus_tag="VQ543_000916"
     CDS             12590..13339
                     /locus_tag="VQ543_000916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000390787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA1(Val) (adenine(37)-N6)-methyltransferase"
                     /protein_id="HET2611658.1"
                     /translation="MEEEQLLKSGERINQLFSTDIKIIQNREVFSYSVDSVLLSRFPR
                     FPKKGLIVDFCAGNGAVGLFASTRTQAQILSVEIQERLADMAERSVRLNGLEEQMQVI
                     CDDLKNMPAHIQGSKVDMILCNPPYFKVDPYSNLNESEHYLLARHEITTNLEEICHSA
                     QSILKSNGRLAMVHRPDRLLDILDTLKRHNLAPKRLQFVYPKREKEANMLLIEAIKDG
                     STSGFKVLPPLIVHNDDGSYTPEIEEIYYGS"
     gene            13329..13628
                     /locus_tag="VQ543_000917"
     CDS             13329..13628
                     /locus_tag="VQ543_000917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HET2611659.1"
                     /translation="MDHKAYMYVLECRDGSYYIGYTTDMRRRLAIHNSGKGAKYTRAR
                     LPVKLIYAQGFASKEEAMSAEALFKRKKRPQKEEFLSENQDRNLLSYFEESWGVL"
     gene            13699..14634
                     /locus_tag="VQ543_000918"
     CDS             13699..14634
                     /locus_tag="VQ543_000918"
                     /EC_number="3.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000036024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese-dependent inorganic pyrophosphatase"
                     /protein_id="HET2611660.1"
                     /translation="MSKILVFGHQNPDSDAIGSSVAFAYLAKEAYGLDTEAVALGTPN
                     EETAFVLNYFGVEAPRVITSAKAEGAEQVILTDHNEFQQSVSDIAEVEVYGVVDHHRV
                     ANFETASPLYMRLEPVGSASSIVYRMFKEHGVAVPKEIAGLMLSGLISDTLLLKSPTT
                     HPTDKIIAPELAELAGVNLEEYGLAMLKAGTNLASKSAEELIDIDAKTFELNGNNVRV
                     AQVNTVDIAEVLERQAEIEAAMQAANESNGYSDFVLMITDIVNSNSEILALGANMDKV
                     EAAFNFKLENNHAFLAGAVSRKKQVVPQLTESFNA"
     gene            14721..15233
                     /locus_tag="VQ543_000919"
     CDS             14721..15233
                     /locus_tag="VQ543_000919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000892254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoylalanyl-D-glutamate--2,
                     6-diaminopimelate ligase"
                     /protein_id="HET2611661.1"
                     /translation="MLENGDLIFVRDGSDMGQAIQTSTGNYSHVAIYLDGMIYHASGQ
                     AGAVCQEPADFFESNHLYDLYVYPEMDIQSVKERACRHLGAPYNASFYPDAAGFYCSQ
                     YIAEILPIFETIPMKFGDGEQEISDFWREYYIELGLPVPLNQAGTNPSQLAASPLLQC
                     KERNLHDSDF"
     gene            15270..15865
                     /locus_tag="VQ543_000920"
                     /pseudo
     CDS             15270..15865
                     /locus_tag="VQ543_000920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809149.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1803 domain-containing protein"
     gene            15966..16160
                     /locus_tag="VQ543_000921"
     CDS             15966..16160
                     /locus_tag="VQ543_000921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000051203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HET2611662.1"
                     /translation="MSLENKLEQATGAVKEGFGKVTGDSKTELEGAVEKTVAKAKDVV
                     EDAKGAVEGAVEGLKNVFTK"
     gene            complement(16206..17651)
                     /locus_tag="VQ543_000922"
     CDS             complement(16206..17651)
                     /locus_tag="VQ543_000922"
                     /EC_number="6.3.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-
                     lysine ligase"
                     /protein_id="HET2611663.1"
                     /translation="MIKIETVLDILKKDGLFREIIDQGHYHYNYSKVIFDSISYDSRK
                     VTEDTLFFAKGAAFKKEYLLSAITQGLAWYVAEKDYEVDIPVIIVNDIKKAMSLIAME
                     FYGNPQEKLKLLAFTGTKGKTTATYFAYNILSQGHRPAMLSTMNTTLDGETFFKSALT
                     TPESIDLFDMMNQAVQNDRTHLIMEVSSQAYLVHRVYGLTFDVGVFLNITPDHIGPIE
                     HPSFEDYFYHKRLLMENSRAVIINSDMDHFSVLKEQVEDQDHDFYGSQFDNQIENSKA
                     FSFSATGKLAGDYDIQLIGNFNQENAVAAGLACLRLGASLEDIKKGIAATRVPGRMEV
                     LTQKNGAKVFIDYAHNGDSLKKLINVVETHQTGKIALVLGSTGNKGESRRKDFGLLLN
                     QHPEIQVFLTADDPNYEDPMAIADEISSYINHPVEKIADRQEAIKAAMAITNHELDAV
                     IIAGKGADCYQIIQGKKESYPGDTAVAENYL"
     gene            17757..19379
                     /locus_tag="VQ543_000923"
     CDS             17757..19379
                     /locus_tag="VQ543_000923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HET2611664.1"
                     /translation="MSHENNHQQAQMLRGTAWLTASNFISRLLGAVYIIPWYIWMGAY
                     AAKANGLFTMGYNIYAWFLLVSTAGIPVAVAKQVAKYNTMREEEHSFALIRSFLGFMT
                     GLGLVFALVLYVFAPWLADLSGVGKDLIPIMQSLAWGVLIFPSMSVIRGFFQGMNNLK
                     PYAMSQIAEQVIRVIWMLLATFIIMKLGSGDYLAAVTQSTFAAFVGMVASFAVLIYFL
                     AQEGSLKRVFETGDKINSKRLLVDTIKEAIPFILTGSAIQLFQILDQLTFINSMSWFT
                     NYSNEDLVVMFSYFSANPNKITMILISVGVSIGSVGLPLLTENYVKGDLKAASRLVQD
                     SLTLLFMFLLPATVGVVMVGEPLYTVFYGKPDSLALGLFVFAVLQSIILGLYMVLSPM
                     LQAMFRNRKAVLYFIYGSIAKLVLQLPTIALFHSYGPLISTTIALIIPNVLMYRDICK
                     VTGVKRKVILKRTILISLLTLVMFLLIGTIQWLLGFFFQPSGRLWSFFYVALVGAMGG
                     GLYMVMSLRTYLLDKVIGKAQADRLRAKFKLS"
     gene            19583..21541
                     /locus_tag="VQ543_000924"
     CDS             19583..21541
                     /locus_tag="VQ543_000924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000748873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HET2611665.1"
                     /translation="MKKSKSKYLTLAGLVLGTGVLLSACGNSSTASKTYNYVYSSDPS
                     SLNYLAENRAATSDIVANLVDGLLENDQYGNIIPSLAEDWTVSQDGLTYTYKLRKDAK
                     WFTSEGEEYAPVTAQDFVTGLQYAADKKSEALYLVQDSVAGLDDYITGKTSDFSTVGV
                     KALDDQTVQYTLVKPELYWNSKTLATILFPVNADFLKSKGDDFGKADPSSILYNGPFL
                     MKALVSKSAIEYKKNPNYWDAKNVFVDDVKLTYYDGSDQESLERNFTAGAYTTARLFP
                     NSSSYEGIKEKYKNNIIYSMQNSTSYFFNFNLDRKSYNYTSKTSDIEKKSTQEAVLNK
                     NFRQAINFAFDRTSYGAQSEGKEGATKILRNLVVPPNFVSIKGKDFGEVVASKMVNYG
                     KEWQGINFADGQDPYYNPEKAKAKFAEAKKELEAKGVQFPIHLDKTVEVTDKVGIQGV
                     SSIKQSIESVLGSDNVVIDIQQLTSDEFDSSGYFAQTAAQKDYDLYHGGWGPDYQDPS
                     TYLDIFNTNSGGFLQNLGLEPGEANDKAKAVGLDVYTQMLEEANKEQDPAKRYEKYAD
                     IQAWLIDSSLVLPSVSRGGTPSLRRTVPFATAYGLTGTKGVESYKYLKVQDKIVTTDE
                     YAKAREKWLKEKEESNKKAQEELAKHVK"
     gene            21713..22648
                     /locus_tag="VQ543_000925"
     CDS             21713..22648
                     /locus_tag="VQ543_000925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000768996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2611666.1"
                     /translation="MKLKLLRVDTKVIMGSFLLVLSSLLALLLPLILKGLIDGSSIEN
                     IGSKVFQSFLIFIGQALFSSIGYYLFSQSGEKKIAKIRKKVIEGLIYAEKSFFDKSQS
                     GELTSAIVNDTSVIREFLITTFPNIILSLVMVLGSIVVLFSLDWNLSLLLFITLPCMM
                     FIILLLSNISEKYSRRLQEEIGFLTGQLTEKIQEHELIKTNQAEKSVQDVLDNCIERV
                     QNNSLKSDRVTSFETPFALLFIFATIAVMLTYGGYRVSAGYISVGTLVSFLIYLFQLL
                     NPISNIANFVTVYSRSKGSSVALENLLAVPKEKFE"
     gene            22673..23325
                     /locus_tag="VQ543_000926"
                     /pseudo
     CDS             22673..23325
                     /locus_tag="VQ543_000926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864981.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
     gene            23483..24577
                     /locus_tag="VQ543_000927"
     CDS             23483..24577
                     /locus_tag="VQ543_000927"
                     /EC_number="2.5.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
                     /protein_id="HET2611667.1"
                     /translation="MSKELHINTILAQAGIKSDEATGALVTPLHFSTTYQHPEFGRST
                     GFDYTRTKNPTRSKAEEVLAAIESADYALATSSGMSAIVLAFSVFPVGSKVLAVRDLY
                     GGSFRWFNQVEQEGRFHFTYANTEEELIAELEKDVDVLYIETPTNPLMLEFDIEKLAK
                     LAHAKGAKVVVDNTFYSPIYQRPIEDGADIVLHSATKYLAGHNDVLAGVVVTNSLELY
                     EKLFYNLNTTGAVLSPFDSYQLLRGLKTLSLRMERSTANAQEVVAFLKDSPAVKEVLY
                     TGRGGMISFKVADETRIPHILNSLKVFSFAESLGGVESLITYPTTQTHADIPAEVRHS
                     YGLTDDLLRLSIGIEDARDLIADLRQALEG"
     gene            24585..25751
                     /locus_tag="VQ543_000928"
     CDS             24585..25751
                     /locus_tag="VQ543_000928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000521357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HET2611668.1"
                     /translation="MGKYDFTSLPNRLGHHTYKWKETETDSEVLPAWIADMDFVVLPE
                     IRQAVQTYADQLVYGYTYASEDLIKEIQKWEATQYGYNFDKEALVFIEGVVPAISTAI
                     QTFTKEGEAVLINTPVYPPFARSVKLNNRRLITNSLVEKDGLFEIDFDQLEKDLVEEE
                     VKLYILCNPHNPGGRVWEKEVLEKIGQLCQKHGVLLVSDEIHQDLTLFGHKHQSFNTI
                     NPAFKNFAIVLSSATKTFNIAGTKNSYAVIENPKLRLAFQKRLLANNQHEISGLGYLA
                     TEAAYRYGKDWLEELKQVFEDHINYVVDLFGKETKIKVMKPQGTYLIWLDFSAYDLTD
                     ETLQELLRNEAKVILNRGLDFGEEGSLHARINIAMPKSLLQEVCQRIVATFAKR"
     gene            25844..28942
                     /locus_tag="VQ543_000929"
     CDS             25844..28942
                     /locus_tag="VQ543_000929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HET2611669.1"
                     /translation="MAKLIPGKIRIEGVALYETGKVDIIKEKNNRLYARVAEEELRYS
                     LEDDLVFCACDSFQKRGYCVHLAALEHFLKNDERGQEILWSLEEGHEEKEAVETKVTL
                     GGKFLNRILSPKSECAYELSAVGQVEAGTNHILWTLRIGQINSQKYYVIRDIPLFLRI
                     VEQRKSYMIGKIYEESLSWEAFDDASQELLTFLHGLTEEGLVPDLFFQNQGRHLFFPL
                     TFFEQGVNLLMALPHFQFDHQVDSYQTLLFQDMHADANLFAFTVTEYSDYFEMEISES
                     PRVNVFYQGAVLFHKGQVYFLTDQQMRLLKEIKALPVGQQGKKYLQFDSSDRDKLASC
                     LTLFIQMGTVSAPERLQIKTFAPSFYFDREEDNRIRLEIQFDYGNRQVSSRQELEELP
                     FSSDADLEERIFQVCLAAGFEADFQSWRQALKAESVYHFFHDIIPVFEKLGHVDLSDK
                     LEELYSLASPQVQIASKGGLLEIQFDFQNIAQEEIDQAMQALVANQDFYIDSSNQVYF
                     FDEETKKIRQNLQELGQFELKDGTLQARKSLAYSLAHLFEGRDRVSFSQEFQNLAQDL
                     THPEDFPLQATQVKADLRDYQEKGIGWLQMLHHYGFGGILADDMGLGKTLQTIAFLTS
                     QVTKESRVLILAPSGLIYNWADEFQKFAPQLDVAVVHGLKASREEILAESHQIYVTSY
                     ATFRQDSEFYQGMAFDFLFLDEAQVMKNAQTKIAQTLRQFVVPSVFALSGTPIENHLG
                     ELWSIFQIVMPGLLPSKKEFMKLPAERVAQFIKPFVMRRKKEEVLTELPDLIEVVYKN
                     ELEDQQKAIYLAQLQQMRDHLAQVSEQEFQRSRVEILSGLMRLRQICDTPALFMEDYQ
                     GASGKLDSLRDLLVQVADGGHRVLIFSQFKGMLEKIEQELPDLGLTSFKITGSTPAKE
                     RQDMTKAFNQGERDAFLISLKAGGVGLNLTGADTVILVDLWWNPAVEAQAIGRAHRMG
                     QEETVEVYRLVTKGTIEEKIQELQEQKKHLVSQVLDGTESRGSLTLAEIREILGISEA
                     ST"
     gene            28990..29607
                     /locus_tag="VQ543_000930"
     CDS             28990..29607
                     /locus_tag="VQ543_000930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
                     /protein_id="HET2611670.1"
                     /translation="MKQERFPLVSDDEVMLTEMPVMNLYDESDLISNIKGEYRDKNYL
                     EWAPIAEEKPVKPIEKQVGKPKKAPLGVKKEGKSYAEVAREEARADLKKKRSANYLTQ
                     DFSLARRHSQPSLVRQGNQPTTPFQKENPGEFVKYSQKLTQSHYILAEEVHSIPTKNE
                     EVSAPAPKKNNYDFLKKSQIYNKKSKQTEQERRVAQELNLTRMTE"
     gene            29617..30951
                     /locus_tag="VQ543_000931"
     CDS             29617..30951
                     /locus_tag="VQ543_000931"
                     /EC_number="6.3.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate--L-alanine ligase"
                     /protein_id="HET2611671.1"
                     /translation="MSKTYHFIGIKGSGMSALALMLHQMGHKVQGSDVEKYYFTQRGL
                     EQAGITILPFDEKNLDGDMEIIAGNAFRPDNNVEIAYADQNGISYKRYHEFLGSFMRD
                     FVSMGVAGAHGKTSTTGMLSHVLSHITDTSFLIGDGTGRGSANAKYFVFESDEYERHF
                     MPYHPEYSIITNIDFDHPDYFTSLEDVFNAFNDYAKQITKGLFVYGEDAELRKITSDA
                     PIYYYGFEAEGNDFVASDLLRSTTGSTFTVHFRGQNLGQFHIPTFGRHNIMNATAVIG
                     LLYTAGFDLNLVREHLKTFSGVKRRFTEKIVNDTVIIDDFAHHPTEIIATLDAARQKY
                     PSKEIVAVFQPHTFTRTIALLDDFAHALNQADAVYLAQIYGSAREVDHGDVKVEDLAN
                     KINKKHQVITVENVSPLLDHDNAVYVFMGAGDIQTYEYSFERLLSNLTSNVQ"
     gene            30961..31425
                     /locus_tag="VQ543_000932"
     CDS             30961..31425
                     /locus_tag="VQ543_000932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET2611672.1"
                     /translation="MEIPIKIIQASKSDLPEIGALQTSSFPAEKQQLSHILEESIRKC
                     ADTFLLARDENQLLGYILSSPQSDNPQYLKVHSLVIESDHQRQGLGTLLLAALKEVAV
                     DLDYKGIRLESPDELLSYFEMNGFVDEEATLLYATSQGYSMIWFNPFYLEEQ"
     gene            31422..31916
                     /locus_tag="VQ543_000933"
     CDS             31422..31916
                     /locus_tag="VQ543_000933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000702438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET2611673.1"
                     /translation="MKIRQARLEDLDRIVELEFENFSVEEAIPPSVFEAHLREIQTSF
                     LVAEKEGRIMGYIEGPVGLHRHLQDQSFTEEIKDYSHEPGGYISVTCLSIAKEAQGLG
                     LGQKLLTALKEVALEDERDGINLTCHDYLIAYYEKHGFVNEGQSQSTFAGETWYDMVW
                     EMKK"
     gene            31997..33646
                     /gene="mltG"
                     /locus_tag="VQ543_000934"
     CDS             31997..33646
                     /gene="mltG"
                     /locus_tag="VQ543_000934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001291636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endolytic transglycosylase MltG"
                     /protein_id="HET2611674.1"
                     /translation="MSEKSREEEKLSFKEQILRDLEKVKGYDEVLKEDEAVVRTPANE
                     PSAEELMTDSLSTVEEIMRKAPTVPTHPSQGVPASPADEIQRETPGVPSHPSQDVPSS
                     PAEESGSRPGPVRPKKLEREYNETPTRVAVSYTTAEKKAEQAGPETPTPATETVDIIS
                     DTSRRSRREGAKPVNPKKEKKSHVKAFVISFLVFLALLSAGGYFGYQYVLDSLLPIDA
                     NSKKYVTVGIPEGSNVQEIGTTLEKAGLVKHGLIFSFYAKYKNYTDLKAGYYNLQKSM
                     STEDLLKELQKGGTDEPQEPVLATLTIPEGYTLDQIAQAVGQLQGDFKESLTAEAFLA
                     KVQDETFISQAVAKYPTLLESLPVKDSGARYRLEGYLFPATYSIKESTTIESLIDEML
                     AAMDKNLSPYYSTIKSKNLTVNELLTIASLVEKEGAKTEDRKLIAGVFYNRLNRDMPL
                     QSNIAILYAQGKLGQNISLAEDVAIDTNIDSPYNVYKNVGLMPGPVDSPSLDAIESSI
                     NQTKSDNLYFVADVTEGKVYYANNQEDHDRNVAEHVNSKLN"
     gene            33717..34199
                     /gene="greA"
                     /locus_tag="VQ543_000935"
     CDS             33717..34199
                     /gene="greA"
                     /locus_tag="VQ543_000935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018370745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreA"
                     /protein_id="HET2611675.1"
                     /translation="MAEKTYPMTLEEKEKLEKELEELKLVRRPEVVERIKIARSYGDL
                     SENSEYEAAKDEQAFVEGQISSLETKIRYAEIVNSDAVAQDEVAIGKTVTIQEIGEDE
                     EEVYIIVGSAGADAFAGKVSNESPIGQALIGKKTGDTATIETPVGSYDVKILKVEKTA
                     "
BASE COUNT        10715 a         6373 c         7776 g         9483 t
ORIGIN      
        1 ccaaggtgaa cgcggtttaa ctggagctaa aggtgaaaaa ggggaccaag gtgaacgcgg
       61 tctcactgga gcccaaggtg aaaaaggaga ccgaggcgaa cgtggtttaa ctggagctaa
      121 aggtgaaaaa ggagcccaag gtcaggcagg tcgtgacggt gtaactccaa ccgtaaccgt
      181 taaagataat aaaaatgacg gcactcatac tatcactatt aacgacggta gaggtaatgt
      241 tacaagtact gttgtaagag atggtttcga tggcgcaagt ccattagttg cgactcaacg
      301 aaatgacgca gataagacaa caactgttat cttctattac gataaaaatg gaaacaatga
      361 attagatgct tctgataaga aattaaaaga agttgtaatt gcagatggtg ctaaaggtga
      421 aaaaggggac aaaggtgaac aaggtcttca agggcgtgat ggtgaacaag gaccaaaagg
      481 agaagatggg aaaaccccaa cagttaaagt aactgatggt caagatggaa cgcatacaat
      541 tacaattaac gatggtaaag gtggtataac tactacagta gtaagagatg gatttgatgg
      601 tgcaagccct cttgtttcta ctcatagaaa tgaagcagat aaaacaacaa ctgttatttt
      661 ctattatgat ctaaatgata ataatcaatt tgatgaagga gatacaaaac ttaaagaagt
      721 tgttatcgca gatggaaaac aaggaccaaa aggtgacaaa ggtgataacg gaaaagatgg
      781 attcacacca gaagtaacag ttacagataa caataacgga acacacacca tcacaatcac
      841 acaaccagac aacagaccat cattaacaac aatcgttaaa aacggtgaag atggaaaaac
      901 accaaaagtc aaagcagaac gagatgatgc gaagaaacaa acaacattaa cattctacat
      961 tgacaaagat ggagatggaa gttacacagc aggaaaagac gagttagttc aaacaacagt
     1021 agttaaagac ggacaagacg gagctgcagg agcatctgga cgtgatggaa aagaagtatt
     1081 aaacggaaaa gtagacccaa caacagaagg taaagatgga gacacattcg taaatacaca
     1141 aacaggagat gtattcgtta agaaaggtaa cacttgggaa ccagcaggaa acatcaaagg
     1201 accgaaaggt gacaaaggtg cagatggtgc caagggtgaa aaaggagccc aaggagaacg
     1261 cggcctgact ggagcgcaag gtgtcaaggg tgaaaaggga gatcagggtg aacgcggtct
     1321 aactggatct aaaggtgaaa aaggagacca aggtgaacgc ggtttaactg gagcgcaagg
     1381 tgccaaaggt gacaaaggtg aacaaggtct tcaaggtcgt gatggagctc aaggaccaaa
     1441 aggcgcagat ggacaaagag gaccagcggg accacaagga ccaaaaggag aacaaggtaa
     1501 tccaggaact ccaggtaaag atggaaaatc tctaattgct gttaaaaatg gaactgaaac
     1561 aaaagtctat gtagaggatc cggctagacc aggacaacca cttaatccaa accaaccatt
     1621 agcaactatc actgatggaa gaaacggtac taatggacaa tcaccaacaa ttacagcgac
     1681 acgaagtgtg caaaatggca aaaatggtgt attagtaaca attacaccag taggaggtcg
     1741 tccacaaaca acatttgtag aggatggaca aaagggtgct gatgggaaaa ccccaacagt
     1801 aacaataact gaggggcaaa acggcacaca tacattaacg gttcataatc caggaagtcc
     1861 agatgtgaca actacgatcc gtgatggagc tacaggacaa gcaggtcgtg atggtaaaga
     1921 tgtattaaac ggaaaagtaa atccacaacc aaaccaaggt aaaaatggag ataaatatat
     1981 taataccgaa accggtgatg tctatgttaa aaacaatgga aactgggata aagaaggcaa
     2041 catcaaaggc cctaaagggg acaaaggtgc agatggtgct aaaggcgaaa aaggagacca
     2101 aggcgaacgc ggcctaactg gagcgcaagg agctaaaggt gcggatggcg cagtaggtcg
     2161 tgatggacgt gacggtaaag acgtgttgaa cggcaaagct aacccagaag cacatcaagg
     2221 taaagacggc gataaatacg ttaatacaga aacaggcgac gtcttcgtta agaataacgg
     2281 caactgggat aaagagggca acatcaaagg ccctaagggt gacaaaggtg aacgcggaga
     2341 agatggtaag actccagaag taactgtaac tccaggtaaa gatggccata gtactgacat
     2401 tacattcact gttccaggta aagatccagt tacagtaaat gttaaggacg gagaaaatgg
     2461 tctgaacggt aaaactccaa aagttgattt acttcgtgtc caaggaaaaa acggaaatcc
     2521 atctcataca attgtgacat tctatacaga tgaaaacaat gacggcaaat atacaccagg
     2581 aactgatgaa cttctaggtt cagaaatgat taaagatggt gctaaaggcg cggacggacg
     2641 agatggtaaa tcattgctta ctgtcaagga tggtaaagaa actaaagttt accaagaaga
     2701 tccagctaac ccaggacaac cattaaatcc agaaaaacca cttgcggtaa ttagagatgg
     2761 agtagatgga aaatcaccta cagttacagc tgttcgtaaa gatgaagcag ggcataaagg
     2821 tgtagaaatc actgttgata accatgatgg ttcacaacca actacagtct ttgttcaaga
     2881 tggtgctaag ggagaaactg gtgcaaccgg tcaggatgga caaactccta caatcactac
     2941 tcaacgtgga caagatggcc aaagcactgt tgtaactatc acaacatcag gtaaagatcc
     3001 agtaaccttc actgtaaaag atggtaagaa tggtaaagat ggccgtgcac cgaaaatcaa
     3061 agtagaagat attacttcac cttcaagaat tagacgcgat acagatgctg ctgcaactcc
     3121 aacgcgtaac ggtatccgtg ttacagttta tgatgatgtt aatgacaatg gggtatacga
     3181 cgaaggtgtc gataaagtat taaatagtaa agatatttat aacggtatag atggacgtga
     3241 tggttcagct ccaactatta ctacaaaaga taatggagat ggaactcaca ctatcacagt
     3301 tcaaaaccca gatggttctg aatcaacaac agttgttaaa gatggtaaag acggtaaaac
     3361 tgcgaatatc actacaacag aaaacccaga tggaagccac acaattacgg tgacaaatcc
     3421 agatggttca actaaagaaa ctgttgttaa aaacggtaaa gacggtaaga ctcctaaagt
     3481 tgaagtaacg gataacaacg atggaactca tactgttaaa gttacagatg gagacggcaa
     3541 tgttaccaac gctatcatca aagatggtaa agacggtaaa gctgcaacag caacaactac
     3601 tgaaaatcca gatggaagcc acacagtaac aatcactaac ccagacggaa ctaagaatga
     3661 gtttgttgtt aagaatggac gtgacggtgt tgacggacgt actccaaccg catctgttcg
     3721 tgataatgga gacggaagtc atacaatcgt tattacaaat ccagaaggtg tgacaactga
     3781 aaccacagtt cgtgatggta aatcaccaaa agtgactata actgatgaac aaaatggaac
     3841 tcataagatc tctgttctaa atggtgacgg aacaactaca acaactacag ttcgtgatgg
     3901 tagagaacca aaacttgaag ttattgataa caacgatggt tcacacacta ttaaagtgac
     3961 aggtgctgat ggtaaaggaa cgacaactac aatctttgat ggtaaatcac caaaagcgaa
     4021 catcgttgat aacggagatg gaactcatac attaacaatc gtagattctg atggtcgtga
     4081 atacaaatct attatcaaag atggtaaaga cggcaaagat agcgtttcac caactgtaac
     4141 tgttaaaaat aataacgatg gaactcacgt tgttacaatc actaatccag atggaagtaa
     4201 gacagaaatg gtgattaaag acggtaaaga tggtaaatca ccaaaagttt ctgttgaaga
     4261 taatggtgat ggtagtcata caatcacaat catcaattct gatggaactg tgacaaaaac
     4321 agttattaaa gatggtagag atggacgtga tggtcgagac ggcaaagacg gtaaagacgg
     4381 taaagatgga aaatgtggat gccaagacaa accagtaaca ccatcaaatg acaaaccagt
     4441 tcctccaaca ccaaatgtgc cgacaccaga agtaccggtt aaacctgtgc cagcgcaacc
     4501 aacaccaaat gtaccgacac cagaagtgcc agtacaacca actccagctg ttccaacacc
     4561 agaagtaccg gttaaaccag taccagcggt tccagaacaa ccagtagtac caacaccggc
     4621 tcaaccagca actccagtaa atgctaaccc agtagcacca actacaggta aagaaaaccg
     4681 tggggacaaa ttacctgaaa ctggaagcca atctgattat atctctgttc ttttaggtag
     4741 cggtattcta ttgagcctat atgtaggacg aagaaaagaa gcttaatcag ccaaaagcag
     4801 tcactaattt ctcgaaagaa gatgataagt gatagatctc gaatgaaaga atattcttag
     4861 aatgattttc ctatgatgga aaagactgct aaaaaccttg agtggtaacg ctcaaggttt
     4921 ttttggatgg ctgatgtttg tctgaaaatc ttgattgaga aataaaaagc caccctatta
     4981 ggtggctata attgatttag actttctaaa attttctatt ttttactgaa tcgcttcgac
     5041 caagtcttga gcttgttttt caagtgagtt taggactgtt tcttcaagaa ccaattttcc
     5101 gtctgcccag gcagagtcat taacacgtgc agcagtgaaa tcaccaacgc cttgtgtacg
     5161 gataaatggc aagaggtctt tgtagatagc gaaaagttga tcgtgccctg cattggctac
     5221 agatgatacg gtgacaaact tgtcttgaag ggcagaaacg ccacgcgtat cagacaagtc
     5281 aagggcacga gatagccagt caagcaagtt ttttactgta ccagggatag agaagttgta
     5341 gactggagag aaaatccaga tagcatccgc aacgagaact gcttcacgag cagcagctac
     5401 agctggatgt gttggaactt ccaaatcttg gctgaagaga ggaagggctg aataatcaag
     5461 gtagctaact tccgctttac cagcaagtgc tttctcagct tcgagcgcca tttggtggtt
     5521 gaaagaacct tgacgtagtg atccgacgat aaataatact tttttagaca tgatgtgtct
     5581 cctttttctt caaattttga gaactctctc gttgttataa aatacattac aacaaaacaa
     5641 aagaacttgc aagaaatttg ctcagagttt atttgaaaat tgtaaaattt cggaaactct
     5701 agtcatttgt gactgaaaaa gtaagaactg tttcactttc aaaatcggtt ttgtttgaag
     5761 ggagaaatag aattggttgc tcaaagcaca gctttgaggt tgcagataaa gctgacgtgg
     5821 tttgaagaga ttttcgaaga gtattcttat attcacttgt aataaagctt aatagatggt
     5881 aaaatagacg agtgaaaaaa agacaaaaca aagcaaaaaa taatctactg tggcagtatg
     5941 gtctagggat gacgattttg tttgtggtta tcagtgcttc ctttctgtat atggtttctc
     6001 ttagcatgaa accctatcaa acagctaaaa gtgaaggaga aaaattagct cagcagtatg
     6061 caggattaga gcaggccgat caggttgatt tatacaatgg cttggaatct tattacagcg
     6121 ttcttggtcg taataaacag caagaagcac ttgctgttct gattggaaaa gatgatcata
     6181 agatttacgt ttatcagcta aatcagggtg tttcacaaga aaaagcagaa acggtttcta
     6241 aggaaaaggg agctggcgaa attgacaaga ttatctttgg tcgttatcaa gataagccaa
     6301 tctgggaagt caagtcagga tctgattttt atctagtaga ttttgaaaca ggagcattgg
     6361 tcaacaagga gggcctatga aattatccaa ccgtgtttta gaaatggaag aaagtgtgac
     6421 tttggctgct ggagcccgtg ccaaagcact gaaggctgag ggtagagata ttttgtctct
     6481 aaccttgggt gagccagatt tcactactcc caaaaatatc caagatgccg ccattgcatc
     6541 gattcgagat gggcgtgctt ctttttatac agtaacctca ggtctgccag agcttaaggc
     6601 ggcggtcaat agctactttg agcgctttta cggctattct gtagcgtcaa atcaagtgac
     6661 agtcgctgcg ggagccaaat attctctcta taccttcttt atggctgtgg tcaatccagg
     6721 tgatgaagtc atcatcccaa ccccatactg ggttagctat ggagatcagg tcaagatggc
     6781 agaaggcgtt cccgtctttg tttctgctaa ggaagacaat cactttaagg tgaccgtaga
     6841 gcagttagaa gcagctcgca ctgacaagac caaggttttg gtgctgaatt cgccatctaa
     6901 tcccacaggt atgatttaca cccgtgagga actcttggca attggaaact gggctgtaga
     6961 aaatgatatt ctcatcctag cagatgatat ctatggccgc ttggtttata atggtcatga
     7021 gttcacaccg atttctagcc tatcggaagc gattcgcaag caaacagtgg tcatcaatgg
     7081 tgtgtctaaa acctatgcca tgactggttg gcggattggt tatgccgttg gagaagcaga
     7141 cattatcgct gccatgtcca agattgcagg tcaaacaact tcgaatccgt cagcagtagc
     7201 ccaatatgca gcagttgagg ctctatcagg tgagcaagat actgtagaaa gcatgcgtca
     7261 ggcctttgaa gaacgtctta ataccatcta tcccctcctt gcagaagtgc caggatttga
     7321 agtggtcaaa ccgcaagggg ccttctatct cttcccaaat gtcaaaaagg ccatggagat
     7381 gaaaggctac acggatgtga cagactttac aactgttatc ttagaagaag ccgaagtggc
     7441 cttggtaaca ggagctggat ttggagcacc agaaaatgtc cgcctcagct atgcgacaga
     7501 cctagacacg cttaaagaag cagtcgaacg cttgaaagca tttatgggta gtgagaatga
     7561 ttgatcattt tgagattaag gtaaaggatt tacaaatttc agaaggattt tataggagtt
     7621 ttctcgctcc tttggactat aaattggctt ttaagactag ttctctaatt agttttctat
     7681 ccccgaacag ccctcatcct ggtggtgatt tttggctgac tcagggaaca caagatcctg
     7741 ttcattttgc ttttttagca gaaaataagg aagaagttca ggcttgttat gaggctggct
     7801 tagaggcagg tgggcgagac aatggggctc ctggttatcg aagtgagcat ccgatttact
     7861 atgctgcttt tatgattgac ctggatggga acaatataga ggtggtttgc cataaagaat
     7921 aaaaaagaaa aggaaaaata atgacaaaac gtgtaacgat tattgacgta aaagactatg
     7981 ttggtcagga agtgacgatt ggcgcttggg ttgccaacaa atcaggaaaa gggaaaatcg
     8041 ctttcttaca attgcgtgat ggaacagcct tctttcaagg tgtggctttt aaaccaaact
     8101 ttgtcgaaaa atttggtgaa gaagtgggac ttgagaagtt tgatgttatc aaacgcttga
     8161 gccaagaaac gtctgtttat gtgacaggta ttgtcaaaga ggacgaacgt tctaaatttg
     8221 gctatgagtt ggacatcaca gacatcgaag tgatcggtga atctcaagac tacccaatca
     8281 caccaaaaga acacggaaca gactttttga tggataaccg tcacttgtgg ctacgctctc
     8341 gtaagcaagt agctgtgttg caaatccgta acgctattat ctatgcaact tatgagttct
     8401 ttgacaagaa cggttttatg aagtttgaca gcccaattct ttcaggaaat gcggcagaag
     8461 attctacaga actctttgaa actgactact tcggaacgcc agcctacttg agccaatcag
     8521 gtcaacttta cctagaagca ggggctatgg ctcttggtcg tgtctttgac tttggtccag
     8581 ttttccgtgc tgaaaaatca aaaacacgcc gtcacttgac tgagttctgg atgatggatg
     8641 ctgagtactc atacttgaca catgatgagt cgcttgactt gcaagaagct tatgtgaaag
     8701 ctcttctaca aggtgttctt gaccgcgcgc ctcaagcctt ggaaaccttg gaacgtgata
     8761 cagaactctt gaaacgctac attgcagagc cattcaaacg tatcacttac gatcaagcca
     8821 ttgacctctt gcaagagcat gaaaatgatg aagatgctga ctacgagcat cttgagcatg
     8881 gtgatgactt tgggtcacca cacgaaactt ggatttcaaa ccactttggt gtgccaacat
     8941 ttgtcatgaa ctatccagca gccatcaagg ccttctacat gaaaccagtt cctggaaatc
     9001 cagagcgcgt gctttgtgca gacttgcttg ctccagaagg ctatggagaa attatcggtg
     9061 ggtctatgcg tgaggaagat tacgatgccc ttgtcgctaa gatggatgaa cttggcatgg
     9121 atcgtacaga atatgaattc taccttgacc ttcgtaaata cggtacagtt ccacacggag
     9181 gatttggtat cggtatcgaa cgtatggtaa ccttcgcagc aggaacaaaa catatccgtg
     9241 aagctattcc attcccacgt atgttgcacc gtatcaaacc ataagaacag gaaaacgccc
     9301 atgtggcgtt ttttcgaatt ctagtgtttt tacttgcgta aaaaaaattt ttctagtata
     9361 atagtttatt gtgagcgaac ctcacttacc ccttgcaaag tcttggggtc attagaccaa
     9421 aaggaggaac atatcaatgg ctaaatacga aattctttat atcattcgtc caaacattga
     9481 agaagaagct aaaaacgctt tggtagcacg ttttgactct attttgactg acaacggtgc
     9541 aactgttgtt gaatcaaaaa cttgggaaaa acgtcgtctt gcatacgaaa tccaagattt
     9601 ccgtgaagga ctttaccaca tcgttaacgt tgaagcaaat gacgatgcag ctcttaaaga
     9661 gtttgaccgt ctttcaaaaa tcaacgctga cattcttcgt cacatgatcg tcaaaattga
     9721 cgcgtaagaa ggtaaactat gattaacaat gttgtacttg tagggcgtat gacacgtgac
     9781 gctgaattgc gttatacccc atcaaatgta gcagttgcga cttttactct tgcagtaaac
     9841 cgtacattta agagtcaaaa tggtgaacgt gaggctgatt ttatcaatgt cgttatgtgg
     9901 cgccaacagg ctgaaaatct tgctaactgg gctaaaaaag gctcacttat cggggtgaca
     9961 ggtcgtatcc agactcgtag ttacgataac cagcaaggac aacgtgtcta cgtgacagag
    10021 gtcgtggctg agaatttcca aatgttggaa agccgtagtg tgcgtgaggg tcacacaggt
    10081 ggagcttact ctgcaccaac tgcaaactat tcagcaccta caaattcagt accagacttt
    10141 tcacgtaatg aaaatccatt tggagcaaca aacccattgg atatttcaga tgatgattta
    10201 ccattctaat ggacaactaa acttataaag gagaaaaaac atggctcaac aacgtcgtgg
    10261 cggattcaaa cgccgtaaaa aagttgatta catcgcagca aacaaaattg aatatgttga
    10321 ttacaaagat actgagcttc ttagccgttt cgtttcagaa cgtgggaaaa tccttcctcg
    10381 tcgtgtaaca ggaacttcag ctaaaaacca acgtaaagta acaacagcta tcaaacgcgc
    10441 tcgcgtaatg gctttgatgc ctttcgtaaa cgaagattaa agaaaagacc cggttgggtc
    10501 tctttttcat gaacttgaaa acaagaaagc gaattaagac cccaacgggt cttttttcac
    10561 aagctttgaa atgagagagc gagttaggct cagtggctcc ctttttacga gtttgaaaac
    10621 aagagaacac attaaaagca cgatggagct ttttcataaa tatgtctttt ttttcatcca
    10681 agaaattaaa ataaaaatga taaacttttt gaaaataggg gatttgccta ctttatgata
    10741 taatggaaag agttagattg aaagaggtag tgagatggac gcgaaattaa gatacaaggc
    10801 aaagaagatc aagattgtct tttttgatat tgatgataca ttgcggaatt caaagacagg
    10861 gtttattcca actacaattc ccactgtttt taaacagttg cgtgaaaaag gaattttaac
    10921 aggaatcgcc tctggacgtg gcatttttgg tgttgttcca gagattcgtg atctcaaacc
    10981 tgactttttt gtaactttga atggggctta tatcgaagat aaaaaaggtc aggtcattta
    11041 tcagcatcag attgaaaagt catatgttga ggagtatatc tcttgggcta agcaagaagg
    11101 aattgagtat ggcttggttg ggagtcatga tgccaagttg tcgactcgca ccgatatgat
    11161 gagtgaagct atcaatccaa tttatcccga cttagatgta gatcccgatt tccatgaaaa
    11221 agaagatatc tatcagatgt ggacttttga agataaggga gatgacttgc acttgcctga
    11281 cagtctctca gacaaacttc gcatggttcg ttggcatcaa cattcgtctg atattgtgcc
    11341 gatttcaggc tccaaagcga cgggggtgga aaaggttgtg gaacaccttg gcttgaaacc
    11401 agagaaggtc atggtttttg gagatggtct caatgacttg gaactctttg attatgctgg
    11461 aatcagcgtt gccatgggaa tttctcatga taaaatcaaa gaaaaagcag attatattac
    11521 aaaaacatta gaagaagatg gcatttttga tgccttagaa gtatttggta tggtagaaaa
    11581 agaattgcat tttccacaag tagacattga aacagtagaa ggtcctcttg cgactattaa
    11641 gaccaatcac ggagacttac gtatcaagct tttccctgaa catgctccta aaacagtggc
    11701 taactttgta tctctttcaa aagatggcta ctatgatggt gtcattttcc accgtattat
    11761 caaggacttt atgatccaag gtggagaccc aactggaact ggtatgggtg gcgagtcaat
    11821 ctacggcgaa tcttttgagg atgaattctc agaagagctt tacaatatcc gtggtgctct
    11881 ttccatggca aatgctggtc caaataccaa cggcagccag ttctttatcg tgcaaaacca
    11941 acacctacct tattctaaga aagaaattac tcgtggtggt tggccagaac cgattgcaga
    12001 aatctatgcc aatcaaggtg ggacacctca cctagaccgc cgtcacacgg tttttggtca
    12061 gttagctgat gaagcatctt acgctgtctt ggatgtcatt gctgctgttg agacaggagc
    12121 tatggacaag ccagttgaag atgttgtaat tgaaactatt gaaatcgagg actaagatga
    12181 aaatcggtga taagctaaag gggcgtatta cagggattca gccctacggt gcctttgttg
    12241 agttagagac gggtgatacg gggctgattc acatttcaga aattcggaca ggatttattg
    12301 aaaatattca tgaaaccttg aaagtcgatg aagaggttca agttcaggta gtggatttag
    12361 atgaatttac ggggaaagcc agtctttcta tccgcacttt ggaggaagaa aagtaccagt
    12421 ttcctagacg gagacgcttt tcaagcgacc gctttaacta cggttttgct ccctttcgac
    12481 gaatgctacc aatctggact ggagaagccc tgcaccattt aaaaaagaag aagtagttta
    12541 gagttttata ttttttgtaa tgttaatata aatttgctat aataggacca tggaagaaga
    12601 acaattatta aaatcaggag agcgcattaa ccagctcttt tcgacagata tcaaaatcat
    12661 tcaaaataga gaggttttta gctattcggt ggatagtgtt ctcttatcac gatttccacg
    12721 ttttcctaag aaggggttga ttgtggattt ctgtgctggg aatggagcag tggggctttt
    12781 tgctagcact cgtactcaag cacagatatt gtctgttgag attcaggagc gtttggcgga
    12841 tatggctgaa cgctctgtcc gtttgaatgg attagaggag caaatgcagg tcatctgcga
    12901 tgatttgaaa aatatgcctg ctcacattca ggggagtaag gtggatatga ttttgtgtaa
    12961 tccaccctat ttcaaggtgg atccttattc taatctgaac gagagtgaac attatctctt
    13021 ggctcgacac gaaatcacga ctaatttgga agaaatctgt catagtgccc agagtattct
    13081 caagtctaat gggcgtttgg ccatggttca tcgtcctgat cgacttctgg atattttgga
    13141 tacgttaaaa cgacataatc tagcccctaa gcgcctgcag tttgtttatc caaaaagaga
    13201 aaaggaagcc aatatgcttt tgattgaggc gatcaaggat ggctcaacaa gtggctttaa
    13261 ggtcttacct cctttgattg tccacaatga tgatggctct tatacgcccg aaatcgaaga
    13321 gatttattat ggatcataag gcttatatgt acgttctgga gtgtcgtgat ggatcctact
    13381 atataggcta tacgactgat atgagaagac gcctcgctat ccacaatagt gggaagggag
    13441 ccaaatatac acgagcacgc ttgccagtca aacttatcta tgctcaaggt tttgccagta
    13501 aggaagaagc catgtcggct gaagctcttt tcaagcgtaa gaagaggcca cagaaggaag
    13561 aatttttatc tgaaaatcaa gatagaaatt tactcagtta ttttgaagaa tcgtggggag
    13621 tcctttgact cctcttacct ttgtcaaaaa gcgaaaaaaa tgctacaata aagaaaataa
    13681 acaaaatgag gtattatcat gtccaagatt ctagtatttg gtcaccaaaa tccagactca
    13741 gatgccatcg ggtcatctgt agcttttgcc taccttgcaa aagaagctta cggtttggat
    13801 acggaagctg ttgcccttgg aactccaaat gaagaaacag cctttgtctt gaactatttt
    13861 ggtgtggaag caccacgtgt tatcacttct gccaaagcag agggggcaga gcaagttatc
    13921 ttgactgacc acaatgaatt ccaacaatct gtatcagata tcgctgaagt agaagtttac
    13981 ggtgttgtag accaccaccg tgtggctaac tttgaaactg caagcccact ttacatgcgt
    14041 ttggagccag ttggatcagc gtcttcaatc gtttaccgta tgttcaaaga acatggtgta
    14101 gctgtgccta aagagattgc aggtttgatg ctttcaggtt tgatttcaga tacccttctt
    14161 ttgaaatcac caacaacaca cccaacagat aaaatcattg ctcctgaatt ggctgaattg
    14221 gctggtgtaa acttggaaga atatggtttg gcaatgttga aagctggtac caacttggct
    14281 agcaaatctg ctgaagaatt gattgacatc gatgctaaga cttttgaact caacggaaat
    14341 aatgtccgtg ttgcccaagt gaacacagtt gacatcgctg aagttttgga acgccaagca
    14401 gaaattgaag ctgcaatgca agctgccaac gaatcaaacg gctactctga ctttgtcttg
    14461 atgattacag atatcgtcaa ctcaaactca gaaatattgg ctcttggtgc caatatggac
    14521 aaggtcgaag cggctttcaa tttcaaactt gaaaacaatc atgccttcct tgctggtgcc
    14581 gtttcacgta agaaacaagt ggtacctcaa ttaactgaaa gctttaatgc gtaagatttt
    14641 gggtgtcagc tcaaaatcgg aaagtctagt ttgccttata tcgaaaggag tttcggctcc
    14701 tttttttcta ggagtgaagt atgttagaaa atggcgattt gatttttgtg agagatgggt
    14761 cagacatggg acaggccatc cagacttcca caggtaacta tagccatgtt gccatttatt
    14821 tggatgggat gatttatcat gctagtggac aggctggtgc tgtctgtcaa gaaccggcag
    14881 acttctttga gtccaatcat ttgtacgacc tctatgttta cccagaaatg gatatccagt
    14941 cggtgaagga aagagcttgc agacatcttg gagcacccta caatgcttct ttctatccag
    15001 atgcagctgg tttctactgc tcccagtata tagcagaaat cctacctatt tttgaaacta
    15061 ttcctatgaa atttggagat ggggaacagg agattagtga tttttggagg gagtattaca
    15121 tagaactagg tctgcctgtt cctctgaacc aagctgggac caatcctagt cagttggcag
    15181 catcgcctct gttacaatgt aaagaaagga atcttcatga ttcagatttt taattcatct
    15241 cgtttgacga gacagccatt tttggagaat tgatccgcta tctggaccag tatgaggatg
    15301 tgattctacg ggaaattaag gctcaatttc cagatgttgc agttgataaa ctcatggaag
    15361 agtatataaa ggcaagcttg attctacgtg aaaataagcg ctattacctc aattttccta
    15421 cgcttgaatc acttgatagt cttgaactgg atcaagagat ttttgtcaga gaagctagtc
    15481 cggtctatca agccttgttg gagcagagtt ttgagacgga attgcgcaat caaatcaatg
    15541 cagctatttt agttgaaaga cggactttgc gcgcattaaa atgaccctgt ccaattattt
    15601 ttacaaggtc aaacagcagt atcctttgac agaaaaacag caggagctct atgacatttt
    15661 aggagatgtt aatcctgagt atgcactcaa gtatatgacg gcttttttgt tgaaatttct
    15721 caaaaaagac cagcttatgc agaaatgccg tgatatcttt gtggacagtt tggttgtctt
    15781 aggctatatt gtgcaaaatg aagatagaaa gtatgagttg gctatcgatt ttgataagga
    15841 gagattaact ttctacttag cgtgatttct tgtttctgag cacattgttt gactttcctt
    15901 agtattcggt ataaactata tgtaaccggt aacacatatc ggaataaact aaaggagaca
    15961 atcatatgtc acttgaaaac aaattggaac aagcaacagg cgctgtcaaa gaaggttttg
    16021 gtaaagttac tggagacagc aagacagaac ttgaaggagc tgttgaaaaa acagttgcta
    16081 aggcaaaaga cgttgtagaa gacgcaaaag gtgctgtaga aggtgccgtt gaaggtttga
    16141 aaaacgtttt tactaaataa taggaaaaaa tcaagggttt cattttccct tgattttttc
    16201 tattcttata aataattttc tgcgacggct gtatctcctg ggtaggattc tttcttgccc
    16261 tggatgattt ggtaacaatc ggctccctta cccgcaataa taactgcatc taattcgtga
    16321 tttgtgatag ccattgccgc cttgatggct tcttggcgat ccgcaatctt ttcaacagga
    16381 tgattgatgt agctactaat ttcatctgca atggccattg ggtcttcata gttagggtca
    16441 tcagcagtca gaaagacttg aatctcaggg tgttgattga ggaggaggcc aaagtcctta
    16501 cgacgacttt ctcccttgtt tcctgttgat cccagaacca gagcaatctt tccggtttga
    16561 tgagtttcaa ccacattgat gagttttttc agactatccc cattgtgggc atagtcgatg
    16621 aagaccttgg ctccattttt ctgagtgagg acttccatac gaccaggaac gcgggttgca
    16681 gcgatgcctt ttttgatgtc ctcaagactt gctccgagac ggagacaagc aagtccagca
    16741 gcaactgcat tttcttggtt gaagttgcca atgagttgga tatcataatc tccagcgagt
    16801 ttacccgtag ctgaaaagct aaaggctttg gaattctcga tttggttatc aaattggcta
    16861 ccatagaaat catggtcttg atcttcaacc tgttctttca agactgagaa gtggtccatg
    16921 tcactgttaa tgatgactgc tcggctattt tccatcaaga gacgcttgtg gtagaaatag
    16981 tcttcaaagc tagggtgttc aatcgggccg atatggtcag gagtgatgtt aagaaagact
    17041 cctacatcaa aggtcagtcc atagactcga tggactagat aggcttgact ggagacttcc
    17101 atgatgaggt gggtacggtc attttgcaca gcctgattca tcatgtcaaa gaggtcaata
    17161 ctctcagggg ttgtcaacgc tgacttaaag aaagtctcgc catcaagagt tgtgttcatg
    17221 gtcgacaaca tagcaggtct atgcccttga gataagatgt tataggcgaa ataggttgct
    17281 gttgtcttac ccttagtacc agtaaaggca aggagtttga gtttctcttg tggattacca
    17341 tagaactcca tggcaatcaa actcatggct ttctttatat cgttcacaat gatgacaggg
    17401 atatcgactt cgtagtcctt ttcagctaca taccaagcta aaccttgtgt tatagcagaa
    17461 agaaggtatt cttttttaaa ggcagcgcct tttgcaaaaa aaagagtgtc ttctgttact
    17521 tttcggctgt cgtagctgat gctatcaaaa ataactttgc tgtagttgta gtggtaatga
    17581 ccttggtcaa taatttcgcg aaaaaggcca tctttcttta aaatatctaa tacggtttca
    17641 atcttaatca tactttctat tgtaaaccga aagtcgtaaa tttacaagta acaaggaaaa
    17701 gtttataatg gaagataagg agtttttcct agttatcaaa attgaatgag gaatctatgt
    17761 cgcacgaaaa caatcaccag caggcccaga tgttacgggg gactgcttgg ctaacggcta
    17821 gtaactttat cagtcgccta ctcggggctg tttacattat cccttggtac atctggatgg
    17881 gggcttatgc agctaaggca aatggtctct ttaccatggg ttacaatatc tatgcttggt
    17941 tcttgttggt ttcaacagcg gggattccag ttgcggtggc caagcaagtt gccaagtata
    18001 ataccatgcg agaagaagag catagctttg ccctgattcg gagcttctta ggctttatga
    18061 caggactagg cctggttttt gctttagtct tgtatgtctt tgctccttgg ctagcagact
    18121 tgtctggcgt gggcaaagac ttgatcccaa tcatgcaaag cttggcttgg ggagtcttga
    18181 ttttcccgtc tatgagtgtt atccgaggat ttttccaagg gatgaataac ctcaaaccct
    18241 atgccatgag ccaaattgct gagcaggtca ttcgtgttat ctggatgctc ctagcaacct
    18301 ttatcattat gaagctcggt tcaggagatt atctagcagc cgttacccaa tcaacctttg
    18361 ctgcctttgt cggtatggta gccagttttg cagtcttgat ttatttcctt gcccaagaag
    18421 gttcactcaa aagagtcttt gaaacaggag ataagattaa cagtaagcgt ctcttggttg
    18481 ataccattaa ggaagccatt ccttttatcc tgacagggtc tgccatccag ctcttccaga
    18541 ttttggatca gctgaccttt atcaatagta tgagctggtt taccaactac agcaatgagg
    18601 acttggttgt catgttttct tatttctcag ccaatcctaa taaaatcacg atgattttga
    18661 tttctgtagg ggtttcgatt gggagtgttg gtttgccact tttgacggaa aactatgtca
    18721 agggggactt gaaagcagct tctcgtctcg ttcaggacag tctcacccta ctctttatgt
    18781 tcttgctacc agcaacggtt ggagtggtta tggtaggaga acctctttat acggtcttct
    18841 atggtaagcc agatagtttg gctctgggct tatttgtctt tgcagttttg cagtctatta
    18901 ttttaggctt gtacatggtc ttgtctccaa tgcttcaggc catgttccgc aaccgcaagg
    18961 ccgttctcta ttttatctat ggttctattg ccaagctagt cttgcaacta cctaccatcg
    19021 ccctcttcca cagttatggt cctttgattt caacaaccat tgctctcatc attcctaacg
    19081 tcttgatgta tcgggatatt tgtaaagtaa ctggtgtcaa gcgcaaggtg attttgaagc
    19141 gaaccatttt aatcagtttg ctgaccctag tcatgtttct gttaatagga accatccagt
    19201 ggctgttagg atttttcttc caaccaagtg gacgtttgtg gagcttcttt tatgtagctc
    19261 ttgtcggtgc catggggggt ggactttata tggttatgag tctgcgtacc tatttattag
    19321 ataaggtaat aggaaaagcc caagcagatc gcctgcgagc aaaatttaag ctttcgtaag
    19381 gtagcattta taaataaaag gaataagttg aacaatcttt taggagaact tgaagcttat
    19441 tcctttttta gcgtaaaaat agctaaaatt atatttcaaa aatagaaaat gaggcttttt
    19501 tcgatttttt ggaaaaaatc attgactaaa caaactaaac gttgtataat aaaacaaata
    19561 tttaaagcag gaggttccgg aaatgaaaaa gtctaagagc aaatatctaa ccttggcagg
    19621 tcttgtcctg ggtacaggag ttttattgag cgcgtgtgga aattctagca cggcgtcaaa
    19681 aacatacaac tatgtttatt caagtgatcc atctagcttg aactatctag cagaaaaccg
    19741 cgcagcaaca tccgatattg ttgcaaattt ggtagacggg ttattagaaa atgaccaata
    19801 tgggaatatt attccatcat tagcagagga ttggactgtt tctcaggacg gtttgaccta
    19861 tacctacaaa cttcgtaagg atgccaagtg gtttacttct gagggagaag aatatgcgcc
    19921 tgtaactgcc caggattttg tgacaggttt gcaatatgca gctgataaaa aatcagaagc
    19981 cttgtatcta gtgcaggact ctgttgctgg tttggatgac tatatcactg gtaaaacaag
    20041 cgacttttca actgtcggtg tcaaggcact tgatgaccaa acggttcaat atactttggt
    20101 taaaccagaa ctttactgga attcaaaaac acttgcaacg atactttttc ctgttaatgc
    20161 agatttcctg aaatcaaaag gggatgattt tgggaaggcg gatccatcta gtattttgta
    20221 caatggacct ttcttgatga aagcacttgt ctcaaaatct gctattgaat ataagaaaaa
    20281 ccctaattac tgggatgcta agaatgtctt tgtagacgat gtgaaattga cctactatga
    20341 tggtagcgac caagaatcac tggaacgtaa ttttacagct ggtgcttata ctacggctcg
    20401 tctttttcct aacagctcca gctatgaagg gattaaagaa aaatacaaaa acaatatcat
    20461 ctatagtatg caaaattcaa cttcatattt ctttaatttt aacctagata ggaagtctta
    20521 caattatact tctaaaacaa gtgacattga aaagaaatcg actcaggaag cagttctcaa
    20581 taaaaacttc cgtcaggcta tcaattttgc ttttgacaga acatcttatg gggctcagtc
    20641 tgaagggaaa gaaggtgcaa caaagatttt gcgtaaccta gtggttcctc caaactttgt
    20701 cagtatcaag ggaaaagact ttggtgaagt tgtagcctct aagatggtca actatggtaa
    20761 ggaatggcaa ggtatcaact ttgcggatgg tcaagaccct tactacaatc ctgagaaagc
    20821 caaggctaag tttgcggaag ctaagaaaga actcgaagca aagggtgttc aattcccaat
    20881 ccacttggat aagactgtgg aagtaacaga taaagtaggc atacaaggag ttagttctat
    20941 caaacaatca attgaatctg ttttaggttc tgataatgta gtgattgaca ttcagcaatt
    21001 aacatcagat gagtttgaca gttcaggcta ctttgctcaa acagctgctc agaaagacta
    21061 tgatttatat catggcggtt ggggacctga ttatcaagac ccgtcaacct atctcgatat
    21121 ttttaatact aatagtggag gatttctgca aaatcttgga ctagagcctg gtgaggccaa
    21181 tgacaaggct aaggcagttg gactggatgt ctatactcaa atgttggaag aagctaataa
    21241 agagcaagat ccagccaaac gttatgagaa atatgctgat attcaagctt ggttgattga
    21301 tagttcttta gttcttccaa gtgtttcgcg tgggggaaca ccatcattga gaagaaccgt
    21361 accatttgct actgcctatg gtttaaccgg tacaaaaggg gttgaatcat ataaatacct
    21421 caaagtacaa gataagattg tcacaacaga cgaatatgca aaagccagag aaaaatggtt
    21481 gaaagaaaaa gaagaatcca ataaaaaagc ccaagaagaa ttggcaaaac atgtcaaata
    21541 aaatctaatt gtagataagt ttgtgtaaga agtctttgtg cttaaaaacg cataatatca
    21601 ggtatataaa atcctagatg ttatgcgttt tgttatagga agatttatta gattttatcc
    21661 tcaaattgag ttattcccga ctttatccgt tgaaatatta taaggagtat ttatgaaatt
    21721 aaaattatta agagtagata ctaaggtgat tatggggagt ttcttacttg ttctgtctag
    21781 tctacttgct ttgttgcttc cccttatctt aaagggttta atagatggga gttctattga
    21841 aaatataggt tccaaagtat ttcaatcgtt tttgattttt attggtcaag ccttgttttc
    21901 ttctattggt tactatctgt ttagtcaatc gggtgaaaaa aagatagcaa aaatcaggaa
    21961 aaaagtgata gaggggttga tttatgcaga gaaatccttc tttgataaga gccaaagtgg
    22021 ggagttgact tctgccattg tcaatgacac gagtgtcatt cgtgagtttt taattacgac
    22081 tttcccaaat attattctga gtttagttat ggtacttggt tccattgtag tcttatttag
    22141 tcttgattgg aatctttctc tacttttatt catcactctt ccttgtatga tgtttattat
    22201 cttgctcctt tccaatatca gtgaaaagta tagtcgtcgt ttacaggagg aaatcggatt
    22261 tttaacaggg caattgactg aaaagattca agaacatgaa ttaattaaga ctaaccaagc
    22321 agagaaaagt gtacaggatg ttttggataa ttgtattgaa agggtacaaa acaattcact
    22381 gaaatcagat agggttactt cttttgagac cccgtttgct ctcttattta tctttgcgac
    22441 tatagctgtg atgctaacct atgggggtta tcgggtcagc gcaggatata tatctgtggg
    22501 aaccttggtt tcgtttttga tttacctctt tcaattactt aatcctatta gtaatatagc
    22561 taattttgta actgtttatt ctaggagcaa gggatcttca gttgcactgg agaacttgct
    22621 tgcagttcct aaagaaaaat ttgagtgagg aaaatcggta tcaggacaag ggttgaattt
    22681 taaccatgtc tattttggtt atgatgaaaa tcgacctgtc ttaaaggata ttacttgttc
    22741 aattttcaag gggcaaaaaa ttgcttttgt tggaccatct ggatcaggaa aatcaacgat
    22801 tgtgcgtttg ttagagcggt tttataaacc gctttcagga gatattctaa tggagcaatc
    22861 aagtatatat gattttaact taaaagaatg gagaagtaaa atcgcttagt aactgatgat
    22921 gaattgatga aagtgctaga cttagtatca ctaggtgatg agattcgctc catgaaagag
    22981 ggactagata ctgaagttgg tgaacgcgga cgactcttgt caggggggca aagccaaaga
    23041 cttcaaatag ctagagccta cttaaaagat gctgaaattc ttatatttga tgaagccact
    23101 gctaatcttg atgcggattc tgagtatgcg attatcagta gcctctattc tgtattaaag
    23161 gagaagacgg ttgtgattat agcgcatcgt ttgtcaacgg taaaagatgt ggattgtatt
    23221 ttcttcttag aggaggggaa aatcactggc tcaggaactc ataaggaact actggaaaat
    23281 catgagcgtt atgctcgttt tgtgcaggag caaatgatag agtgaaggtg tcttttgaga
    23341 ttcaccattt tatagtctat taaagggagc aggaaaaact ccctttttat atagtttgaa
    23401 actataacta gctcttgaaa agaagaaaat gagttgatga aaataagtgg tacaatagtt
    23461 actatagatt tggaggtatt gtatgagcaa ggaattacac attaacacaa ttttggccca
    23521 ggcgggtatt aagtcagatg aagcgacagg tgcattggtg acaccgcttc atttttcaac
    23581 gacctatcag catccagagt ttggtcgatc tactgggttt gactatacgc gcactaaaaa
    23641 tccaactcgt agtaaggctg aggaagtctt ggcggctatt gagtcagcag actatgccct
    23701 agcgactagc tcagggatgt cagctattgt actggccttt agcgtctttc cagtaggaag
    23761 taaggtcttg gcagtgcgtg atctttacgg tggttctttt cgctggttta accaagtgga
    23821 gcaggaaggt cgtttccatt ttacctatgc caatacagaa gaagagttga ttgccgagtt
    23881 agaaaaggat gtggatgttc tctatatcga aaccccaacc aatcccttga tgttggaatt
    23941 tgatatcgaa aaactagcaa aattggctca tgctaagggt gccaaagtgg tggtggacaa
    24001 taccttctat agccctatct accaacgtcc gattgaagat ggagcagata tcgttctcca
    24061 ttcagcaacc aagtatctag caggccacaa tgatgtcttg gctggagtgg ttgtgaccaa
    24121 tagtttagaa ctatacgaga agctttttta caatctcaat acaacagggg cagtcttgtc
    24181 tccatttgac agctaccagt tgcttcgtgg tctcaagacc ttatctcttc gtatggagcg
    24241 ctcaacagct aacgcccaag aagtggttgc ctttttgaag gattctccag cagttaagga
    24301 agttctctac actggtcgtg gaggcatgat ttcctttaaa gtagccgatg aaacacgcat
    24361 tcctcatatt ttgaacagtc tcaaggtctt ctcttttgcg gaaagtttgg gcggagtgga
    24421 aagtcttatt acttatccaa cgactcaaac tcatgctgat attccagcag aagtacgcca
    24481 ttcttatggt ttgacagatg acctcttgcg tttgtctatt gggattgagg atgctagaga
    24541 tttgattgca gatttgcgcc aagccttaga aggataagac aaagatggga aaatatgatt
    24601 ttacaagcct gcccaaccgt ttagggcacc atacctataa atggaaagaa acagaaacgg
    24661 atagtgaagt tctaccagct tggatagcgg atatggactt tgtggtcttg cctgaaatcc
    24721 gccaagccgt gcaaacttac gcagaccaac tggtttatgg ttatacctat gccagtgaag
    24781 acttaattaa ggaaattcaa aagtgggaag ctacacaata cggttacaac tttgacaaag
    24841 aggctcttgt ctttatcgag ggtgtggtac cagccatctc aacagctatt caaaccttta
    24901 caaaagaagg cgaggcggtt ttaattaaca cgcctgtcta cccacccttt gctcgcagtg
    24961 tcaagttgaa taatcgtaga ttgattacta attccttagt ggaaaaggat ggtctgtttg
    25021 agattgactt tgaccaactt gaaaaggatt tggtggaaga ggaggttaaa ctctatattc
    25081 tttgcaaccc tcacaatcct ggtggacgtg tttgggaaaa agaagtgttg gagaagattg
    25141 gccaactttg ccaaaaacac ggtgttttgt tagtttcgga tgagattcac caagatttga
    25201 ccctctttgg tcacaaacac cagtctttca ataccatcaa tcctgccttc aaaaattttg
    25261 ctatcgtctt gagcagtgcc actaaaacat ttaatattgc tggaacaaaa aattcctatg
    25321 cagtcattga aaatcctaag ttgagactgg ctttccagaa acgcctgttg gccaataatc
    25381 agcatgaaat ttcaggcttg ggttatttgg cgacagaagc tgcctatcga tacggtaaag
    25441 attggctaga ggaactcaag caagtctttg aagaccacat caattatgtg gtggatctat
    25501 ttggaaaaga gactaaaatc aaggtcatga aaccgcaagg tacctacttg atttggcttg
    25561 acttttcagc ctatgacctg actgatgaaa cattgcaaga gttgttgaga aatgaagcca
    25621 aggttatcct caaccgtggt ttggattttg gagaggaagg aagtctccat gcccgcatca
    25681 atatagctat gcccaaatct ctgttgcaag aagtctgtca gcggattgtg gctacttttg
    25741 ccaaacgtta aaaatccagc cttctaggag aaaagtcttc ctagaaggct attttcatag
    25801 gcgaaaatat ggtataataa aaagataagg taaaggtgaa aatatggcta aattgattcc
    25861 ggggaaaatt cgtatcgaag gtgttgccct ttatgaaact ggtaaggttg atatcatcaa
    25921 ggaaaagaac aatcggctct acgctcgcgt tgcagaagaa gaactgcgct atagtttaga
    25981 ggatgatttg gttttttgtg cctgtgattc ttttcaaaag aggggctact gtgtgcattt
    26041 ggcagcgcta gagcattttc tgaaaaatga tgagcgtggt caggaaatct tgtggagtct
    26101 ggaagaaggt catgaagaaa aagaggccgt tgaaaccaag gtgaccttgg gtggcaagtt
    26161 tttgaatcga attttatctc caaaatcaga atgcgcctat gagttatcag ctgtgggtca
    26221 ggtggaagca ggaaccaatc atatcttgtg gactctgaga atcggccaaa tcaatagcca
    26281 aaaatactat gtcattcggg atattccact ttttttaagg attgtcgagc agagaaagtc
    26341 gtatatgatt ggcaagattt atgaggagtc tctttcttgg gaagcctttg atgatgccag
    26401 ccaagaactt ttgactttct tgcacggact aacggaggaa gggctggttc cagacctctt
    26461 tttccaaaac caaggtcggc acctcttttt ccctctgacc ttttttgagc agggtgtgaa
    26521 tttactgatg gccttgcccc attttcaatt tgaccatcaa gtggatagct accaaaccct
    26581 gctttttcag gatatgcatg ctgatgccaa tctatttgcc tttacagtaa cagaatactc
    26641 ggactatttt gaaatggaaa tcagtgagag tcctagggtc aatgtctttt atcagggagc
    26701 agtacttttc cataaaggtc aggtttattt tttaacagac cagcagatgc gtcttctcaa
    26761 ggaaattaaa gcgttacctg tgggtcaaca aggaaagaaa tacctgcaat ttgatagcag
    26821 tgatcgagac aaattggcct cctgtctgac tctttttatc cagatgggca ccgtttcagc
    26881 tccagaacgt ctacaaatca aaacttttgc gccctctttt tactttgaca gggaagaaga
    26941 taatcggatt cgtttagaaa ttcagtttga ttatggaaat agacaggtat ctagccgaca
    27001 agagctagaa gaattaccat tttcaagtga cgcggactta gaagaaagaa ttttccaagt
    27061 ctgtttggct gcgggctttg aagccgattt tcaatcttgg cgtcaggcct taaaagcgga
    27121 gtctgtctat catttttttc atgatatcat tccagtcttt gaaaaactcg ggcatgttga
    27181 cctatcagat aaactagaag agctttatag cctagcgagt cctcaggtgc agattgcctc
    27241 caagggaggt ctcttggaaa tccagtttga ttttcaaaat attgcccagg aggaaatcga
    27301 ccaagccatg caggccttgg ttgccaatca ggatttttat attgattcgt ctaatcaagt
    27361 ttactttttc gatgaagaaa ccaagaaaat tcgccaaaat ctacaggaac tggggcaatt
    27421 tgaattaaaa gatgggacct tgcaggctcg gaaatccttg gcctacagtt tagctcatct
    27481 ctttgaaggg cgagaccgtg tttctttttc acaagaattc cagaatctgg cccaggattt
    27541 gacgcatcca gaggactttc ctttgcaagc aactcaggtc aaggctgact tgcgagatta
    27601 tcaggaaaag ggaattggct ggttgcagat gctccatcat tatggttttg gtgggatttt
    27661 ggctgatgat atgggacttg ggaaaaccct tcagaccatt gcttttttga ctagtcaagt
    27721 gacaaaagaa agtcgagtct tgattctcgc tccgtcgggt ttgatttaca actgggcgga
    27781 tgagtttcag aaatttgccc cacagttgga tgtggctgtt gttcatggtt tgaaagcaag
    27841 tcgtgaggag attcttgccg agagccatca aatctatgtg actagctatg ccaccttccg
    27901 tcaggacagt gagttttatc aggggatggc ctttgacttc cttttcttag atgaggctca
    27961 ggtcatgaaa aatgcccaga ccaagattgc ccagaccttg agacaatttg tggtgccgtc
    28021 ggtctttgcc ttgtcaggaa ctccgattga aaaccatctg ggtgagttgt ggtctatttt
    28081 ccaaatcgtc atgcccggac ttttgccaag caagaaagaa tttatgaaat tgccagcaga
    28141 gcgagtggct cagtttatca agcctttcgt gatgcgacgc aagaaagaag aagttctgac
    28201 tgaattgcca gacttgattg aggtggttta taaaaatgaa ctggaagacc agcaaaaggc
    28261 tatttacctt gcccagttac aacagatgcg agaccatctg gctcaagtgt cagaacagga
    28321 atttcagcga agtcgtgtgg aaattttatc tggtttgatg cgcttgcgtc aaatatgtga
    28381 cactcctgcc ctgtttatgg aagattatca gggagccagc ggcaaactag atagtctccg
    28441 agacctactg gtacaggtgg cagacggcgg acaccgtgtc ttgattttct ctcagttcaa
    28501 gggaatgttg gaaaaaattg aacaagaact gccagacttg ggcctgactt cctttaaaat
    28561 tacgggttca accccagcca aggaaagaca agacatgacc aaggccttta atcaaggaga
    28621 aagagatgcc tttctgattt ccctcaaggc tggtggggtc ggtctgaacc tgacaggtgc
    28681 agatacagtg atcttggttg acctttggtg gaatcctgcg gtggaagcgc aagccattgg
    28741 ccgtgcccat cggatgggtc aggaagaaac ggttgaggtc tatcgcttgg tgaccaaggg
    28801 aaccattgaa gaaaaaattc aggaactcca agaacaaaag aaacatctgg tgtcacaagt
    28861 attggacggc acagagtcac gtggtagtct gaccctagca gaaattagag aaattttggg
    28921 aatttctgaa gccagcactt gaaaaatcaa gacaatacgc tataatgaag tgttgaaagg
    28981 aaatagaaaa tgaaacaaga acgatttcca ttggtgtcag atgacgaggt catgttgact
    29041 gaaatgccag tcatgaatct ctatgatgag tctgatctga tcagtaatat caagggtgag
    29101 tatcgagata aaaattattt agaatgggct cctattgctg aagaaaaacc agtaaaaccg
    29161 attgaaaagc aagtagggaa acctaaaaaa gctcctttag gggttaaaaa agaaggaaag
    29221 agctatgcgg aggtggcgcg tgaagaagcg cgtgcagact tgaaaaagaa acgctctgct
    29281 aactatctaa ctcaggattt cagccttgcg agacgtcatt ctcagcccag tctagttaga
    29341 cagggcaatc aaccgacaac tcctttccaa aaggaaaatc ctggtgaatt tgtcaaatat
    29401 agccaaaaat tgacccagtc tcattatatc ttggcggaag aagttcattc tatccctacc
    29461 aagaatgaag aagtgtcagc acctgctcca aagaaaaaca attatgattt tctaaagaag
    29521 agccaaatct acaataaaaa aagtaaacaa acagaacaag aacgtcgggt tgcccaagag
    29581 ttgaatctga ccagaatgac agaataggga gaaaacatgt caaagacata tcattttatc
    29641 ggaattaagg gatcagggat gagtgccttg gccttgatgt tgcaccagat ggggcacaag
    29701 gttcagggat cagatgttga aaagtactac tttacccaac gcggtcttga gcaggcagga
    29761 attaccattc ttccttttga tgaaaagaat ctagacggtg atatggaaat tatcgctgga
    29821 aatgcctttc gtccagataa caacgtcgaa attgcctatg cggaccaaaa tggtatcagc
    29881 tacaaacgtt accatgagtt tctaggtagc tttatgcgtg actttgttag catgggagta
    29941 gcaggagcac atggaaaaac ttcaacgaca ggtatgttgt ctcatgtctt gtctcacatt
    30001 acagatacca gcttcttgat tggagatggg acaggtcgtg gttcggccaa tgccaaatat
    30061 tttgtctttg aatctgacga atatgagcgt cacttcatgc cttaccaccc agaatactct
    30121 attatcacca acattgactt tgaccatcca gattatttca caagtctcga ggatgttttc
    30181 aatgccttta acgactatgc caaacaaatc accaagggtc tttttgtcta tggtgaagat
    30241 gctgaattgc gtaagattac gtctgatgca ccaatttatt attatggttt tgaagctgaa
    30301 ggcaatgact ttgtagctag tgatcttctt cgttcaacaa ctggttcaac cttcaccgtt
    30361 catttccgtg gacaaaactt ggggcaattc cacattccaa cctttggtcg tcacaatatc
    30421 atgaatgcga cagccgttat tggtcttctt tacacagcag gatttgattt gaacttggtg
    30481 cgtgagcact tgaaaacatt ttccggtgtt aaacgtcgtt tcactgagaa aattgtcaat
    30541 gatacagtga ttatcgatga ctttgcccat catccaacag aaattattgc gaccttggat
    30601 gcggctcgtc agaaataccc aagcaaggaa attgtagcag tctttcaacc gcataccttt
    30661 acaagaacca ttgccttgtt ggacgacttt gcccatgctt taaaccaagc agatgctgtt
    30721 tatctagcgc aaatttatgg ctcggctcgt gaagtagatc atggtgacgt taaggtagaa
    30781 gacctagcca acaaaatcaa caaaaaacac caagtgatta ctgttgaaaa tgtttctccg
    30841 ctcctagacc atgacaatgc tgtttacgtc tttatgggag caggagacat ccaaacctat
    30901 gaatactcat ttgagcgtct cttgtctaac ttgacaagca atgttcaata ggatgttccc
    30961 atggaaattc caattaagat cattcaggca agcaagtctg atttgcctga gataggggca
    31021 cttcagacct cgtcttttcc agctgaaaag cagcaacttt cccatatttt agaagaaagt
    31081 atccgtaagt gtgcggatac ctttcttcta gctagggatg aaaatcaact tttaggctat
    31141 attttatcaa gtccccagtc agacaatccg caatatctaa aagtacattc tttagtcatc
    31201 gagtctgacc atcagagaca gggcttggga acacttcttc ttgcagcctt gaaagaggtg
    31261 gcagttgatc tggattacaa agggattcgt ttggagagtc ctgatgagct gctttcctat
    31321 tttgaaatga acggttttgt tgatgaagaa gcaactttgc tctatgcaac tagccagggc
    31381 tatagtatga tttggtttaa tcccttttat ctggaggaac aatgaaaatc agacaagcaa
    31441 gattagaaga tttggatcgg attgttgaac ttgaatttga aaatttttcg gtcgaagaag
    31501 ccattcctcc ttctgtcttt gaagcacatt tgagagaaat tcagacctct tttctggttg
    31561 ctgaaaaaga aggaagaatc atgggttata tcgaaggacc agttggcctg caccgccatc
    31621 tgcaagacca gtcttttaca gaagaaataa aagactatag tcatgagcct ggtggttata
    31681 tctctgtgac ctgtctgtct attgccaagg aggcacaggg actcggactg ggtcagaaat
    31741 tgctgacagc tttgaaagaa gttgctcttg aagatgagag agatggcatt aatctaacct
    31801 gtcatgacta tctcatcgcc tattatgaaa aacatggatt tgtcaacgaa ggccagtccc
    31861 agtcaacctt tgcaggggaa acatggtatg atatggtctg ggaaatgaaa aaataagtta
    31921 ggaaaagtat catagattgc tttttttgga cttttaagat ataatattat ggattatcaa
    31981 caaggaggaa aaacttttga gtgaaaagtc aagagaagaa gagaaattaa gctttaaaga
    32041 gcagattctg agagatttag aaaaagtaaa aggctatgat gaagttctga aagaagatga
    32101 ggcagtagtt cgcactcctg caaatgaacc ttcagctgaa gaactcatga ctgattcctt
    32161 gtcaacggta gaggagatta tgagaaaagc tcctaccgtg cctactcacc caagtcaagg
    32221 tgtaccagct tctccagcag atgagattca aagagaaact cctggtgttc caagtcatcc
    32281 aagtcaagat gtaccttctt ctccagcgga agaaagtgga tcaagaccag gtcctgttag
    32341 acctaagaaa cttgaaagag aatacaatga aaccccaaca agggtagctg tttcctatac
    32401 gacggcagag aaaaaagcag aacaagcagg tccagaaaca cctacgcctg ctacagaaac
    32461 agtggatatc atcagcgata catcacgtcg tagccgtaga gaaggagcaa aacccgttaa
    32521 tcctaagaaa gagaagaagt cacatgtgaa agcttttgtg atttcattcc ttgtattcct
    32581 tgccttgctc tcagcaggtg gttactttgg ttaccagtac gtgctagatt ctttgttacc
    32641 tatcgatgct aattctaaga aatatgtgac ggttggaatt ccagaaggtt caaacgttca
    32701 agaaatcggt acgacgcttg aaaaagctgg tttggtaaag catggtctga tttttagttt
    32761 ttatgccaag tataaaaatt ataccgactt gaaagcaggt tactacaatt tgcaaaagag
    32821 tatgagtaca gaagacttac tcaaagagtt gcaaaaaggt ggaacagatg aaccgcaaga
    32881 acctgtactt gcgactttga caattccaga aggttatacc ttggatcaga ttgctcaagc
    32941 tgtgggtcaa ttgcaaggtg acttcaaaga gtctttgaca gcggaggctt tcttggctaa
    33001 agttcaagat gagacgttta tcagtcaagc agtagcgaaa tatcctactt tactggaaag
    33061 tttgcctgta aaagacagcg gtgcgcgtta tcgtttggaa ggataccttt tcccagctac
    33121 atactctatc aaggaaagca caactattga gagcttgatt gatgagatgt tagctgctat
    33181 ggataagaac ctatctcctt actatagtac tatcaaatct aaaaatttga ctgtcaatga
    33241 gttgttgacc attgcttcct tggtcgaaaa agaaggtgcc aagacagaag atcgtaagct
    33301 cattgcaggt gtattctaca atcgtttaaa tcgtgatatg ccacttcaaa gtaatattgc
    33361 aatcttgtat gcccaaggaa aactggggca aaatatcagt ctagctgagg atgttgcgat
    33421 tgataccaac attgattcac cttataatgt ttataaaaat gtaggtctca tgcctggtcc
    33481 agtcgatagt ccaagtctgg atgcgattga gtcaagcatc aatcaaacta agagcgataa
    33541 cctctacttt gtagcagatg tcacagaagg caaggtctac tatgctaaca atcaagaaga
    33601 ccacgaccgc aatgtcgctg aacatgtcaa cagcaaatta aactaaacaa actaaaatta
    33661 tgtgatacgt cacataattt tctttagaaa atattatcag aagaaagttg agaaaaatgg
    33721 cagaaaaaac atatcctatg acccttgagg aaaaggaaaa acttgaaaaa gaattagaag
    33781 aattgaaatt ggttcgtcga ccagaagtgg tagaacgcat taagattgcc cgttcatacg
    33841 gtgacctttc agaaaacagt gagtacgaag cagctaagga tgaacaagcc tttgtcgaag
    33901 gacaaatctc tagcttagaa acaaaaatcc gctatgctga aatcgtcaat agcgacgcag
    33961 ttgcccagga cgaagtagcg attggtaaaa cagtcaccat ccaagaaatt ggtgaggacg
    34021 aagaagaagt ttatattatc gtaggttcag ctggtgcgga tgcctttgca ggtaaggttt
    34081 caaatgaaag cccaattggg caggccttga ttggcaagaa aacaggtgac acagcaacca
    34141 ttgaaacgcc tgttggtagc tatgatgtaa aaatcttgaa ggttgaaaaa acagcctaaa
    34201 aacagaaaaa ggagtgggga ggcgatgtgc ttcactcact cctttttcca ttttgctatt
    34261 cttcgaaaat ctcttcaaac cacgtcagcg tcgccttgcc gtatgtatgg ttactgactt
    34321 tgtcagtttc atctacaacc tcaaaac
//
LOCUS       DAVBEO010000019        33324 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 009
            SAMEA1678075-rid20185393.denovo.019, whole genome shotgun sequence.
ACCESSION   DAVBEO010000019 DAVBEO010000000
VERSION     DAVBEO010000019.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678075
            Sequence Read Archive: ERR226392
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 33324)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33324)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980207.1
            Genome Coverage       :: 150x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:50:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 72 of 147
            Pseudo Genes (incomplete)         :: 72 of 147
            Pseudo Genes (internal stop)      :: 42 of 147
            Pseudo Genes (multiple problems)  :: 32 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33324
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678075-rid20185393.denovo.019"
                     /strain="KS 009"
                     /db_xref="taxon:1313"
     gene            <1..327
                     /locus_tag="VQ543_000936"
     CDS             <1..327
                     /locus_tag="VQ543_000936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine motif-containing protein"
                     /protein_id="HET2611676.1"
                     /translation="KPQTEKPEEETPREEKPQSEKPESPKPTEEPEEESPEESEEPQV
                     ETEKVEEKMREAEDLLGKIQDPIIKSNAKETLTGLKNNLLFGTQDNNTIMAEAEKLLA
                     LLKESK"
     gene            749..979
                     /locus_tag="VQ543_000937"
     CDS             749..979
                     /locus_tag="VQ543_000937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIA"
                     /protein_id="HET2611677.1"
                     /translation="MESIGIGLVIVSHSKHIAEGVVELISKVAKDVPITYVGGTEGGG
                     IGTSFDQVDRVVSENPADTLLAFFDLGSAIKC"
     gene            1383..2096
                     /locus_tag="VQ543_000938"
     CDS             1383..2096
                     /locus_tag="VQ543_000938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000499426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjjG family noncanonical pyrimidine
                     nucleotidase"
                     /protein_id="HET2611678.1"
                     /translation="MFYKFLLFDLDHTLLDFDAAEDVALTQLLKEEGVADIQAYKDYY
                     VPMNKALWKDLELKKISKQELVNTRFSRLFAHFGQEKDGSFLAQRYQFYLAQQGQTLS
                     GAHDLLDSLIERDYNLYAATNGITAIQTGRLAQSGLAPYFNQVFISEQLQTQKPDALF
                     YEKIGQQIAGFSKEKTLMIGDSLTADIQGGNNAGIDTIWYNPHHLENHTQAQPTYEVY
                     SYQDLLDCLDKNILEKITF"
     gene            2154..2756
                     /locus_tag="VQ543_000939"
     CDS             2154..2756
                     /locus_tag="VQ543_000939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2611679.1"
                     /translation="MSEVDFNEAVNYEFTSDTCQLANSIYQSLFKFFDKKNFSGDLIF
                     TWKSPSLVKEGDYIGRRDSQVDNLRVIGNIFPNYLTNRKYSLNMNRNGCMGDFPHDFF
                     DIYLDHVAKYAYEQKVNNIKEYYPLKRAILHQENALYFRFFSNFDDFLEKNYLKTIWQ
                     VSKETPFSEMDFNMFKNISEKIIFERGSKMLNDLKSNYKK"
     gene            2892..3545
                     /locus_tag="VQ543_000940"
     CDS             2892..3545
                     /locus_tag="VQ543_000940"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HET2611680.1"
                     /translation="MEHSSWHALIKAQLPEGYFGKINQFMEQVYSQGIIYPPKEKVFQ
                     ALLTTLLEEVKVVILGQDPYHGPGQAQGLSFSVPDSIPAPPSLQNILKELSDDIGVKK
                     SHDLTAWAEQGVLLLNACLTVPAGQANGHAGQIWEPFTDAVIQVVNHLDRPVVFVLWG
                     AYARKKKALVTNPHHLIIESAHPSPLSVYRGFWGSKPFSKANAFLKETGQEPIDWLR"
     gene            3555..4019
                     /locus_tag="VQ543_000941"
     CDS             3555..4019
                     /locus_tag="VQ543_000941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003012002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HET2611681.1"
                     /translation="MPQLATICYIDNGKELLMLHRNKKPNDVHEGKWIGVGGKLERGE
                     TPQECAAREILEETGLKAKPVLKGVITFPEFTPDLDWYTYVFKVTEFEGDLIDCNEGT
                     LEWVPYDEVLSKPTWEGDHTFVEWLLEDKPFFSAKFVYDGDKLLDTQVDFYE"
     gene            4032..5300
                     /locus_tag="VQ543_000942"
     CDS             4032..5300
                     /locus_tag="VQ543_000942"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000924471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotase"
                     /protein_id="HET2611682.1"
                     /translation="MLLIKNGRVMDPKSGLDQVCDVLVQDGKIIKIAPEITEEGAETI
                     DATGLVVAPGLVDIHVHFREPGQTHKEDIHTGALAAAAGGFTTVVMMANTSPTISDVE
                     TLQAVLQSAAKEKINVKTVATITKNFNGKNLTDFKALLEAGAVGFSDDGIPLESSKIV
                     KEAMEEAKKLNTFISLHEEDPGLNGVLGFNENIAREHFHICGATGVAEYAMMARDVMI
                     AYATKAHVHIQHLSKEESVKVVEFAQGLGAEVTAEVAPQHFSKTEALLLTQGSNAKMN
                     PPLRLESDRRAVIEGLKSGVITVIATDHAPHHVDEKNVEDITKAPSGMTGLETSLSLG
                     LTYLVEAGELSLMELLEKMTYNPAKLYNFEAGYLAENGPADITIFDAKADRLVDSHFA
                     SKAANSPFIGETLKGQVKYTICKGQIVYQA"
     gene            5314..5574
                     /locus_tag="VQ543_000943"
     CDS             5314..5574
                     /locus_tag="VQ543_000943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2611683.1"
                     /translation="MNYFRKRRERQAKSNSGIYCPAANRSKIQYETKEKADHAVQYDN
                     GGLVRSYYCRTCACWHTTSKSNKPPLSLKNYGLKLFGLDKSE"
     gene            5585..6946
                     /gene="pdrM"
                     /locus_tag="VQ543_000944"
     CDS             5585..6946
                     /gene="pdrM"
                     /locus_tag="VQ543_000944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000278532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium-coupled multidrug efflux MATE transporter
                     PdrM"
                     /protein_id="HET2611684.1"
                     /translation="MYKTKCLREKLVLFLKIFFPILIYQFANYSASFVDTAMTGQYNT
                     MDLAGVSMATSIWNPFFTFLTGIVSALVPIIGHHLGRGKKEEVASDFYQFIYLALGLS
                     VVLLGMVLFLAPTILNHIGLEAAVAAVAVRYLWFLSIGIIPLLLFSVIRSLLDSLGLT
                     KLSMYLMLLLLPLNSGFNYLLIYGAFGVPELGGAGAGLGTSLAYWVLLGISVLVLFKQ
                     EKLKALHLEKRIPLNMDKIKEGVRLGLPIGGTVFAEVAIFSVVGLIMAKFSSLIIASH
                     QSAMNFSSLMYAFPMSISSAMAIVVSYEVGAKRFDDAKTYIGLGRWTALIFAAFTLTF
                     LYIFRGNVASLYGNDPKFIDLTARFLTYSLFFQLADTFAAPLQGILRGYKDTVIPFYL
                     GLLGYWGVAIPVATLFDSLTDFGAYSYWIGLIISLIVSGALYRWRLTVIMKRFESLAK
                     SKR"
     gene            7100..8068
                     /locus_tag="VQ543_000945"
     CDS             7100..8068
                     /locus_tag="VQ543_000945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine pyrophosphate-dependent dehydrogenase
                     E1 component subunit alpha"
                     /protein_id="HET2611685.1"
                     /translation="MSTLDKNLLLEMFRKMEEIRRMDLKIAQLVKKGKVPGMTHFSVG
                     EEAANVGAMLALNPDDLITSNHRGHGQAIAKGIDLNGMMAEILGKYTGTCKGKGGSMH
                     IADLDAGNLGANGIVGGGMGIAVGAALSQQMQNTGKIVVCFFGDGATNEGVFHEAVNM
                     ASIWNLPVIFYCINNGYGISADIKKMTNIEHIHQRSAAYGIPGMFIEDGNNVIDVYEG
                     FQKAVDHVRSGNGPVLIESVTYRWLGHSSSDPGKYRTREEVELWKQKDPIENLRNYLI
                     ENNIASAEELEEIQAQVKEAVEASVKFAEESPFPPLESAFEDIYAD"
     gene            8084..9076
                     /locus_tag="VQ543_000946"
     CDS             8084..9076
                     /locus_tag="VQ543_000946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000448722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-ketoacid dehydrogenase subunit beta"
                     /protein_id="HET2611686.1"
                     /translation="METKTMSFRDTIILAMSEEMRRDENVFLMGEDVGVFGGDFGTSV
                     GMLEEFGPERVRDCPISEAAISGAAAGAAMTGLRPIVDMTFMDFSVIAMDNIVNQAAK
                     TRYMFGGKGQVPMTVRCAAGNGVGSAAQHSQSLESWFTHIPGLKVVAPGTPADMKGLL
                     KSSIRDKNPVIILEYKSEFNQKGEVPVDPDYTIPLGVGEIKRQGTDVTVVTYGKMLRR
                     VVQAAEELAEEGISVEIVDPRTLVPLDKDIIINSVKKTGKVVLVNDAHKTSGYISEIS
                     AIISESEAFDYLDAPIRRCAGEDVPMPYAQNLENAMIPTVESIKDAIRKTYNKE"
     gene            9294..10337
                     /locus_tag="VQ543_000947"
     CDS             9294..10337
                     /locus_tag="VQ543_000947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoamide acetyltransferase"
                     /protein_id="HET2611687.1"
                     /translation="MADDKLRATPAARKLADDLGINLYDVSGSGANGRVHKEDVETYK
                     DTNVVRISPLAKRIALEHNIAWQEIQGTGHRGKIMKKDVLALLPENIENDSIKSPAQI
                     EKVEEVPDNVTPYGEIERIPMTPMRKVIAQRMVESYLTAPTFTLNYEVDMTEMLALRK
                     KVLEPIMEATGKKTTVTDLLSLAVVKTLMKHPYINASLTEDGKTIITHNYVNLAMAVG
                     MDNGLMTPVVYNAEKMSLSELVVAFKDVIGRTLDGKLAPSELQNSTFTISNLGMFGVQ
                     SFGPIINQPNSAILGVSSTIEKPVVVNGEIVIRPIMSLGLTIDHRVVDGMAGAKFMKD
                     LKELIETPISMLI"
     gene            10401..12086
                     /gene="lpdA"
                     /locus_tag="VQ543_000948"
     CDS             10401..12086
                     /gene="lpdA"
                     /locus_tag="VQ543_000948"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HET2611688.1"
                     /translation="MPKAGVDMTEGQIVQWNKKVGEFVKEGEILLEIMTDKVSMELEA
                     EEDGYLIAILKGDGETVPVTEIIGYLGEERENIPTAGAASPEASPVPVASTSNDDGKS
                     DDAFDIVVIGGGPAGYVAAIKAAQLGGKVALVEKSELGGTCLNRGCIPTKTYLHNAEI
                     IENIGHAANRGIVIENPNFTVDMEKLLETKSKVVNTLVGGVAGLLRSYGVTVHKGIGT
                     ITKDKNVLVNGSELLETKKIILAGGSKVSKINVPGMQSPLVMTSDDILEMNEVPESLV
                     IIGGGVVGIELGQAFMTFGSKVTVIEMMDRIVPAMDAEVSKNLRLILERKGMTILTGT
                     KLQEIIEENGQLRIKVEGKDDIIASKALLSIGRMPDLEGIGEVEFELDRGCIKVNEYM
                     ETSVPGIYAPGDINGTKMLAHAAFRMGEVSAENALKGNHAVAKLNLTPAAIYTLPEVA
                     AVGLTEEQAREKYDVAIGKFNFAANGRAIASDAAQGFVKVIADKKYGEIIGVHIIGPA
                     AAELINEASSIIEMEITVEEMLKTIHGHPTYSEVMYEAFADVLGMAIHSPKKK"
     gene            12150..13139
                     /locus_tag="VQ543_000949"
     CDS             12150..13139
                     /locus_tag="VQ543_000949"
                     /EC_number="6.3.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000873976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HET2611689.1"
                     /translation="MKYIINHSNDTAFNIALEEYAFKHLLDEDQIFLLWINKPSIIVG
                     RHQNTIEEINRDYVRENGIEVVRRISGGGAVYHDLNNLNYTIISKEDENKAFDFKSFS
                     TPVINTLAQLGVKAEFTGRNDLEIDGKKFCGNAQAYINGRIMHHGCLLFDVDLSVLAN
                     ALKVSKDKFESKGVKSVRARVTNIINELPKKITVEKFRDLLLEYMKKEYPEMTEYVFS
                     EEELAEINHIKDTKFGTWDWNYGKSPEFNVRRGTKFTSGKVEVFANVTESKIQDIKIY
                     GDFFGIEDVAAVEDVLRGVKYEREDVLKALKTIDITRYFAGISREEIAEAVVG"
     gene            complement(13206..14276)
                     /gene="xerS"
                     /locus_tag="VQ543_000950"
     CDS             complement(13206..14276)
                     /gene="xerS"
                     /locus_tag="VQ543_000950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000817875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerS"
                     /protein_id="HET2611690.1"
                     /translation="MKREILLERIDKLKQLMPWYVLEYYQSKLAVPYSFTTLYEYLKE
                     YDRFFSWVLESGISNADKISDIPLSVLENMSKKDMESFILYLRERPLLNANTTKQGVS
                     QTTINRTLSALSSLYKYLTEEVENDQGEPYFYRNVMKKVSTKKKKETLAARAENIKQK
                     LFLGDETEGFLTYIDQEHPQQLSNRALSSFNKNKERDLAIIALLLASGVRLSEAVNLD
                     LRDLNLKMMVIDVTRKGGKRDSVNVAAFAKPYLENYLAIRNQRYKTEKTDTALFLTLY
                     RGVPNRIDASSVEKMVAKYSEDFKVRVTPHKLRHTLATRLYDATKSQVLVSHQLGHAS
                     TQVTDLYTHIVNDEQKNALDSL"
     gene            complement(14860..16410)
                     /locus_tag="VQ543_000951"
     CDS             complement(14860..16410)
                     /locus_tag="VQ543_000951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chloride channel protein"
                     /protein_id="HET2611691.1"
                     /translation="MEEQSEIVRSKKEFAFASSTILSQVGRGIIVGLIVGIIVGSFRF
                     LIEKGFHLIQGVYQDQGYLVRNLFVLVLFYILICWLSAKLTRSEKDIKGSGIPQVEAE
                     LKGLMSLNWWGILWKKYVLGILAIASGLMLGREGPSIQLGAVGGKGIAKWLKSSPVEE
                     RSLIASGAAAGLAAAFNAPIAALLFVVEEVYHHFSRFFWVSTLAASIVANFVSLLMFG
                     LTPVLDMPDNIPPMTLDQYWIYLVMGIFLGFSGFLYEKAVLNVGRVYDLIGQKIHLDR
                     AYYPILAFIIIIPVGIFLPQIIGGGNQLVLSLTEQNFSFQVLLAYFLIRFIWSMISYG
                     SGLPGGIFLPILALGSLLGSLVGVICVNLGLVSQEQFPIFVILGMSGYFGAISKAPLT
                     AMILVTEMVGDIRNLMPLGLVTLVSYIIMDLLKGTPVYEAMLEKMLPEEVSSEGEVTL
                     IEIPVSDKIAGKQVHELNLPHNVLITTQVHNGKSQTVNGSTRMYLGDMIHLVIPKSEI
                     GKVKDLLL"
     gene            complement(16426..17205)
                     /locus_tag="VQ543_000952"
     CDS             complement(16426..17205)
                     /locus_tag="VQ543_000952"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HII"
                     /protein_id="HET2611692.1"
                     /translation="MATIKEIKELLVTVKELESPIFLDLEKDNRSGVQKEISKHKRAI
                     QAELDENLRLESMLSYEKELYKQGLTLIAGIDEVGRGPLAGPVVAAAVILPKNCKIKG
                     LNDSKKIPKKKHLEIFQVVQDQALSIGIGIIDNQVIDQVNIYEATKLAMQEAISQLSP
                     QPEHLLIDAMKLDLPISQTSIIKGDANSLSIAAASIVAKVTRDELMKEYDQQFPGYDF
                     ATNAGYGTAKHLEGLTKLGVTPIHRTSFEPVKSLVLGKKES"
     gene            complement(17192..18043)
                     /gene="ylqF"
                     /locus_tag="VQ543_000953"
     CDS             complement(17192..18043)
                     /gene="ylqF"
                     /locus_tag="VQ543_000953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YlqF"
                     /protein_id="HET2611693.1"
                     /translation="MATIQWFPGHMSKARRQVQENLKFVDFVTILVDARLPLSSQNPM
                     LTKIVGDKPKLLILNKADLADPAMTKEWRQYFESQGIQTLAINSKEQVTVKVVTDAAK
                     KLMADKIARQKERGIQIETLRTMIIGIPNAGKSTLMNRLAGKKIAVVGNKPGVTKGQQ
                     WLKTNKDLEILDTPGILWPKFEDETVALKLALTGAIKDQLLPMDEVTIFGINYFKEHY
                     PEKLAERFKQMKIEEEAPVIIMDMTRALGFRDDYDRFYSLFVKEVRDGKLGNYTLDTL
                     EGLDGND"
     gene            complement(18250..18426)
                     /locus_tag="VQ543_000954"
     CDS             complement(18250..18426)
                     /locus_tag="VQ543_000954"
                     /inference="COORDINATES: protein motif:HMM:NF012948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HET2611694.1"
                     /translation="MQAGIPTDNEVSYALIYQQETLPATGSSTSALTALGLLAVGSLV
                     LLVHNMTGTVFCSL"
     gene            complement(18478..24369)
                     /gene="iga"
                     /locus_tag="VQ543_000955"
     CDS             complement(18478..24369)
                     /gene="iga"
                     /locus_tag="VQ543_000955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000417171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="immunoglobulin A1 protease"
                     /protein_id="HET2611695.1"
                     /translation="MEKYFGEKQERFSFRKLSVGLVSATISSLFFMSVLASSSVDAQE
                     TAGVHYKYVADSELSSEEKKQLVYDIPTYVENDDETYYLVYKLNSQNQLAELPNTGSK
                     NERQALVAGASLAALGILIFAVSKKKVKNKTVLHLVLVAGMGNGVLVSVHALENHLLL
                     NYNTDYELTSGEKLPLPKEISGYTYIGYIKEGKTTSDFEVSNQEKSAATPTKQQKVDY
                     NVTPNFVDHPSTVQAIQEQTPVSSTKPTEVQVVEKPFSTELINPRKEEKQSSDSQEQL
                     AEHKNLETKKEEKISPKEKTGVNTLNPQDEVLSGQLNKPELLYREETIETKIDFQEEI
                     QENPDLAEGTVRVKQEGKLGKKVEIVRIFSVNKEEVSREIVSTSTTAPSPRIVEKGTK
                     KTQVIKEQPETGVEHKDVQSGSIVEPAIQPELPEAVVSDKGEPEVQPTLPEAVVTDKG
                     ETEVQPESPDTVVSDKGEPEQVAPLPEYKGNIEQVKPETPVEKTKEQGPEKTEEVPVK
                     PTEETPVNPNEGTTEGTSIQEAENPVQPAEESTTNSEKVSPDTSSENTGEVSSNPSDS
                     TTSVGESNKPEHNDSKNENSEKTVEEVPVNPNEGTVEGTSNQETEKPVQPAEETQTNS
                     GKIANENTGEVSNKPSDSKPPVEESNQPEKNGTATKPENSGNTTSENGQTEPEKKLEL
                     RNVSDIELYSQTNGTYRQHVSLDGIPENTDTYFVKVKSSAFKDVYIPVASITEEKRNG
                     QSVYKITAKAEKLQQELENKYVDNFTFYLDKKAKEENTNFTSFSNLVKAINQNPSGTY
                     HLAASLNANEVELGPDERSYIKDTFTGRLIGEKDGKNYAIYNLKKPLFENLSGATVEK
                     LSLKNVAISGKNDIGSLANEATNGTKIKQVHVDGVLAGERGVGGLLAKADQSSIAESS
                     FKGRIVNTYETTDAYNIGGLVGHLTGKNASIAKSKATVTISSNTNRSDQTVGGLAGLV
                     DQDAHIQNSYAEGDINNVKHFGKVAGVAGYLWDRTSGEEKHAGELTNVLSDVNVTNGN
                     AITGYHYTGMKVANTFSSKANRVFNVTLEKDEVVSKESFEERGTMLDASQIVSKKAEI
                     NPLTLPTVEPLSTSGKKDSDFSKIAHYQANRALVYKNIEKLLPFYNKSTIVKYGNLVK
                     ENSLLYQKELLSAVMMKDDQVITDIVSNKQTANKLLLHYNDHSSEKFDLKYQTDFANL
                     AEYNLGNTGLLYTPNQFLYDRDSIVKEVLPELQKLDYQSDAIRKTLGISPEVKLTELY
                     LEDQFSKTKQNLGDSLKKLLSADAGLASDNSVTRGYLVDKIKNNKEALLLGLTYLERW
                     YNFNYGQVNVKDLVMYHPDFFGKGNTSPLDTLIELGKSGFNNLLAKNNVDTYGISLAS
                     QHGTTDLFSTLEHYRKVFLPNTSNNDWFKSETKAYIVEEKSTIEEVKTKQGLAGTKYS
                     IGVYDRITSATWKYRNMVLPLLTLPERSVFVISTMSSLGFGAYDRYRSSDHKAGKALN
                     DFVEENARETAKRQRDHYDYWYRILDEQSREKLYRTILLYDAYKFGDDTTSGKATAEA
                     KFDSSNPAMKNFFGPVGNKVVHNQHGAYATGDGVYYMSYRMLDKDGAITYTHEMTHDS
                     DQDIYLGGYGRRNGLGPEFFAKGLLQAPDQPSDATITINSILKHSKSDSTEGSRLQVL
                     DPTERFQNAADLQNYVHNMFDLIYMMEYLEGQSIVNKLSVYQKMAALRKIENKYVKDP
                     ADGNEVYATNVVKELTEAEARNLNSFESLIDHNILSAREYQSGDYERNGYYTIKLFAP
                     IYSALSSEKGTPGDLMGRRIAYELLAAKGFKDGMVPYISNQYEEDAKQQGQTINLYGK
                     ERGLVTDELVLKKVFDGKYKTWAEFKTAMYQERVDQFGNLKQVTFKDPTKPWPSYGTK
                     TINNVDELQALMDQAVLKDAEGPRWSNYDPEIDSAVHKLKRAIFKAYLDQTNDFRSSI
                     FENKK"
     gene            complement(24578..25756)
                     /locus_tag="VQ543_000956"
     CDS             complement(24578..25756)
                     /locus_tag="VQ543_000956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2611696.1"
                     /translation="MTLPVRKSLHDAVLQASKADTWEQATKEWNEVSLIFNGIGRSNC
                     VCRNAIKYAYELFNGVTGQRLFPIGSDCVRHFHRLPLDQQLEEEEKLLRKVENLTRKA
                     QKKEKIKVNKSDFDERLLKWLWEKGVFKPNRGNQFAPERDYQLFLEVFQGGSWTKAEP
                     KKKARMEEVLEKCIKPFLLGKSDDQLYLVKLGKEKIDYEQELRIQAEKERKKRDKIAK
                     QYADNLVLAMGPAERAYQDYFGFTETLTQEERKWEKILFGKNRAERAIKAKQYQKELE
                     KDQRIASQDPIERKQKQTWILNSYFRELPEEKARFSRLLLEYRKSGEVPFSTEYLSDH
                     LIDFFYKMKAFEFEIAPEQVRDFLKKSLQEDHRSSAQGSWIEGILLNCLKPFLERLVI
                     "
     gene            complement(25926..29576)
                     /gene="addA"
                     /locus_tag="VQ543_000957"
     CDS             complement(25926..29576)
                     /gene="addA"
                     /locus_tag="VQ543_000957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000767270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase-exonuclease AddAB subunit AddA"
                     /protein_id="HET2611697.1"
                     /translation="MKLIPFLSEEEIQKLQEAEANSSKEQKKTAEQIEAIYTSGQNIL
                     VSASAGSGKTFVMAERILDQLARGVEISQLFISTFTVKAATELKERLEKKISKKIQET
                     DDVDLKQHLGRQLADLPNAAIGTMDSFTQKFLGKHGYLLDIAPNFRILQNQSEQLLLE
                     NEVFHEVFEAHYQGKQKETFSHLLKNFAGRGKDERGLRQQVYKIYDFLQSTSNPQKWL
                     SESFLKGFEKADFTSEKEKLTEQIKQALWDLESFFRYHLDNDAKEFAKAAYLENVQLI
                     LDEICSLNQESDSQAYQAVLARVVAISKEKNGRALTNASRKADLKPLADAYNEERKTQ
                     FAKLGQLSDQITILDYQERYHQDTWKLAKTFQTFMSHFVEAYRQRKRQENAFEFADIS
                     HYTIEILENFPQVRESYQERFHEVMVDEYQDTNHIQERMLELLSNGHNRFMVGDIKQS
                     IYRFRQADPQIFNEKFQRYAQNPQEGKLILLKENFRSSSEVLSATNDVFERLMDQEVG
                     EINYDNKHQLVFANTKLTPNPDNKAEFLLYDKDDTGEEEESQTETKLTGEMRLVIKEI
                     LKLHQEKGVAFKEIALLTSSRSRNDQILLALSEYGIPVKTDGEQNNYLQSLEVQVMLD
                     TLRVIHNPLQDYALVALMKSPMFGFDEDELARLSLQKAEDKVHENLYEKLVNAQKMAS
                     SQKGLIHTALVEKLKQFMDILASWRLYAKTHSLYDLIWKIYNDRFYYDYVGALPNGPA
                     RQANLYALALRADQFEKSNFKGLSRFIRMIDQVLEAQHDLASVAVAPPKDAVELMTIH
                     KSKGLEFPYVFILNMDQDFNKQDSMSEVILSRQNGLGVKYIAKMETGAVEDHYPKTIK
                     LSIPSLTYRQNEEELQLASYSEQMRLLYVAMTRAEKKLYLVGKGSREKLESKEYPAAK
                     NGKLNSNTRLQARNFQDWLWAISKVFTKDKLNFSYRFIDEDQLTREAIGELETKSPLQ
                     DSSQADNRQSDTIKEALEMLKEVEVYNTLHRAAIELPSVQTPSQIKKFYEPVMDMEGV
                     EIAGQGQSVGKKISFDLPDFSTKEKVTGAEIGSATHELMQIIDLSQQLTLASLTETLK
                     QVQTSQAVRDKINLDKILAFFDTALGQEILANTDHLYREQPFSMLKRDQKSQEDFVVR
                     GILDGYLLYENKIVLFDYKTDRYDEPSQLVDRYRGQLALYEEALSRAYSIENIEKYLI
                     LLGKDEVQVVKV"
     gene            complement(29573..32848)
                     /gene="rexB"
                     /locus_tag="VQ543_000958"
     CDS             complement(29573..32848)
                     /gene="rexB"
                     /locus_tag="VQ543_000958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent nuclease subunit B"
                     /protein_id="HET2611698.1"
                     /translation="MKLLYTDIRTSLTEILTREAEELVAAGKRVFYIAPNSLSFEKER
                     AVLECLSQQASFSITVTRFAQMARYLVLNDLPVKTTLDDIGLGLAFYKCLAELDPKDL
                     RVYGAIKQDPQLIQQLIELYHEMTKSQMSFLDLENLTDEDKRADLLLIFEKVTAYLNQ
                     GQLAQGSQLSHLIEAIENDKVSSDFNQITLVIDGFTRFSAEEERVVDLLHGKGVEIVI
                     GAYASKKAYTSPFSEGNLYQASVKFLHHLASKYQTPAQDCSQTHEKMDSFDKASRLLE
                     SSYDFSELALDVDEKDRENLQIWSCLTQKEELELVARSIRQKLHENSDLSYKHFRILL
                     GDVASYQLSLKTIFDQYQIPFYLGRSEAMAHHPLTQFVESILALKRYRFRQEDLINLL
                     RTDLYTDLSQSDIDAFEQYIRYLGINGLPAFQQTFTKSHHGKFNLERLNVLRLRILAP
                     LETLFASRKQKAENLLQKWSVFLKEGAVTKQLQDLTTTLEAVEQERQAEVWKAFCHVL
                     EQFATVFAGSQVSLEDFLALLHSGMSLSQYRTIPATVDTVLVQSYDLIAPLTADFVYA
                     IGLTQDNLPKISQNTSLLTDEERQNLNQTTEEGVQLLIASSENLKKNRYTMLSLVNSA
                     RKQLFLSAPSLFNESESKESAYLQELIHFGFRRREKRMNHKGLSKEDMGSYHSLLSSL
                     VAYHQQGEMSDTEQDLTFVKVLSRVIGKKLDQQGLENPAIPISPSSKTLAKDTLQALY
                     PAKQEFYLSTSGLTEFYRNEYSYFLRYVLGLQEELRLRPDARSHGNFLHRIFERALQL
                     PNEDSFDQRLEQAIQETSQEREFEAIYQESLEAQFTKEVLLDVARTTGHILRHNPAIE
                     TIKEEANFGGKDQAFIQLDNGRSVFVRGKVDRIDRLKANGAIGVVDYKSSLTQFQFPH
                     FFNGLNSQLPTYLAALKREGEQNFFGAMYLEMAEPVQSLMAVKSLAGAVVEASKSMKY
                     QGLFLEKESSYLGEFYNKNKANQLTDEEFQLLLDYNAYLYKKAAEKILAGRFAINPYT
                     ENGRSIAPYVQQHQAITGFEANYHLGQARFLEKLDLADGKRLVGEKLKQAWLEKIREE
                     LNR"
     gene            complement(33048..33203)
                     /locus_tag="VQ543_000959"
                     /pseudo
     CDS             complement(33048..33203)
                     /locus_tag="VQ543_000959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000710121.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
BASE COUNT         9515 a         6539 c         6861 g        10409 t
ORIGIN      
        1 aaacctcaga cagaaaaacc tgaggaagaa acccctcgag aagagaaacc gcaaagcgag
       61 aaaccagagt ctccaaaacc aacagaggaa ccagaagaag aatcaccaga ggaatcagaa
      121 gaacctcagg tcgagactga aaaggttgaa gaaaaaatga gagaggctga agatttactt
      181 ggaaaaatcc aggatccaat tatcaagtcc aatgccaaag agactctcac aggattaaaa
      241 aataatttac tatttggcac ccaggacaac aatactatta tggcagaagc tgaaaaacta
      301 ttggctttat taaaggagag taagtaaagg tagcagcatt ttctaactcc taaaaacagg
      361 ataggagaac gggaaaacga aaaatgagag cagaatgtga gttctagttc tcattttttt
      421 catgaaaatg tgcaaaatat agtagattga aactagaata gtatacctct acttctaaaa
      481 cattgttaga aatcgatttg actgtcctgt tcttatttca ttttactata tcttaacaga
      541 tagtgtaaat aaagataaac tatttactgg ctaattaatc agttaaacac tagttaagga
      601 gtaatgatga aaaaaagaac aatactatta ttgatggcca gtctgttagc tcttgtctta
      661 ggagcatgtg gtttcttgga catattgatc ctggatcatt ctcatcagga ttactcttta
      721 ctgctatttt agaaactggg gtggtttgat ggaaagtatt ggtattggtc ttgttatcgt
      781 ttcacattcc aaacacattg cagaaggtgt tgttgaactg attagtaaag tagctaaaga
      841 tgttccgatt acttatgtag gaggaaccga gggcggagga attggaacga gttttgatca
      901 agtagatagg gttgtttccg aaaatccagc agatacttta cttgcctttt ttgacctagg
      961 ttctgctata aaatgttaag taaatgattt caaaatcaga aagggattgc tttgggcagt
     1021 tcctttttaa tgtaaatgta aaaggagtag aatcatagtg tttctaaatt gtgaatcaat
     1081 caaaactgat tgtgatgggg ctattctagc tttagaatcc ttcaaaaatt aaaatttaag
     1141 gcaatcaatt acttggaaga gtatgaaagc atttagttta taggaattct aggcctagaa
     1201 ttacatatgt atttatgaag ataggggtgt tcgatagtta gtattgttct gttctgaaag
     1261 atttgagctg tcagttgtat agaaagtgtt cgaatttttt ttaagtgatt aaattagtta
     1321 attgtatgag gttctttatg atataatgtt cttaatgaat tttcagaaag gaaaacctca
     1381 aattgttcta caaatttcta ctcttcgacc tcgaccacac tcttcttgat tttgatgctg
     1441 ctgaggatgt ggctttgacc caacttctaa aagaagaagg agttgcggat attcaggctt
     1501 ataaagatta ttacgttcct atgaacaagg ctctctggaa agacttggag ctgaagaaaa
     1561 tcagtaaaca agagctggtt aacacgcgct tttctcgttt atttgctcat tttggacagg
     1621 aaaaagacgg tagttttctt gcccagcgtt accaatttta cctcgcccag cagggacaaa
     1681 cactatcggg cgctcatgat ctcttggaca gcctcattga gcgtgattat aacttgtatg
     1741 ctgcgacaaa tggcattact gccattcaga caggacgttt ggctcaatct ggtctagcac
     1801 cttatttcaa tcaagtcttt atctcagaac agttgcaaac tcaaaagccg gatgctctct
     1861 tttatgaaaa gattggccag caaattgctg gatttagtaa agaaaagacg ctgatgattg
     1921 gagattctct aaccgccgac attcaaggtg gcaataatgc ggggattgat actatctggt
     1981 ataatcctca tcacctcgaa aatcacacac aagcccagcc gacttacgaa gtctattctt
     2041 accaagactt gctggattgt ttagataaaa atattcttga aaagatcaca ttttaaagga
     2101 gacgagctaa tgactacaaa aaagctaata ttactattga agagtacatt gaaatgtctg
     2161 aagttgattt taatgaagct gttaattatg aatttacatc tgacacttgt caattagcaa
     2221 atagtattta tcaatctctt tttaagtttt ttgataagaa aaatttctct ggcgatttaa
     2281 tttttacttg gaaatctcca tcattagtca aagaagggga ttatattggg agaagggatt
     2341 cacaagtaga taatcttaga gtaataggaa atatatttcc gaattatctt actaatcgaa
     2401 aatatagcct caatatgaat cgtaatggct gtatgggaga ttttcctcat gacttttttg
     2461 atatatacct agatcatgta gcaaaatatg cctacgaaca aaaagttaat aatattaaag
     2521 agtattatcc tttaaaaaga gcgattttac accaagagaa tgcattgtat tttcgatttt
     2581 tttctaattt tgacgacttt ttagaaaaaa attatttaaa gactatatgg caagtttcta
     2641 aagaaactcc tttttctgaa atggatttta atatgtttaa aaatatttca gaaaagataa
     2701 tcttcgaaag aggtagtaaa atgcttaatg atttaaaaag taattataaa aaatagccag
     2761 tctttataaa ctgtattcac gtattcaaat cgtatatagt cgatttatta aatctttaga
     2821 taaactgtaa aaagtggttt ccatagccac tttttgctat aatagaggca gtaaaaatga
     2881 aggagtcggc tatggaacac tcgtcttggc atgctttgat taaggcgcaa ttacctgagg
     2941 gttatttcgg gaaaatcaat cagtttatgg agcaggtcta ttctcagggg attatttatc
     3001 cacccaagga aaaggttttt caggctctct tgacaacact gcttgaagaa gttaaggtgg
     3061 taattctagg gcaagacccc tatcacggac caggtcaagc gcagggcttg agtttttctg
     3121 tacctgactc tatcccagct ccaccatcct tgcaaaatat cttgaaagaa ttgtcagatg
     3181 atatcggagt taagaaatct catgatttga cagcttgggc tgagcaagga gtcttgcttc
     3241 ttaatgcttg tttgactgtt cctgctggac aggccaatgg tcatgctggt caaatctggg
     3301 agccttttac tgatgctgtg attcaggtgg tcaatcatct agatagacca gtcgtttttg
     3361 tactctgggg agcttatgca cgtaagaaga aggccttagt taccaatcct catcacttga
     3421 ttatcgaatc agcccatcca agtcctttgt cggtttatag aggattttgg ggttccaagc
     3481 ccttttccaa ggccaatgca ttcttaaaag agacaggaca agagccaatc gattggctta
     3541 gataaggaga aaatatgcct cagttagcga cgatttgcta cattgataat gggaaagaac
     3601 tgctcatgct ccatcgtaat aagaaaccca atgatgtcca tgaagggaaa tggattggtg
     3661 tgggtggtaa gctagagaga ggagagacgc cccaggaatg cgcggcgcgt gaaatccttg
     3721 aagaaacagg gctcaaagcc aagccagttc taaaaggtgt catcactttt cctgaattta
     3781 caccagattt agactggtac acctatgttt ttaaggtgac ggagtttgag ggcgacttga
     3841 ttgactgcaa tgaggggacg ctagaatggg ttccctatga cgaggttttg agcaagccga
     3901 cttgggaagg tgaccacacc tttgttgagt ggcttttaga ggataaaccc ttcttttcag
     3961 ccaagtttgt ttatgatggg gataaattgt tggataccca agttgatttc tatgaataaa
     4021 ggagaaagca gatgctacta atcaaaaatg gtcgtgtaat ggatcctaag tctggtttgg
     4081 atcaagtttg tgatgtctta gttcaagatg ggaaaattat caaaattgcg cctgagatca
     4141 cggaagaagg agcagaaacg attgatgcta ctggtcttgt ggttgctcct ggtttggtcg
     4201 atattcatgt gcatttccgt gaacctggtc aaacacataa agaagacatt catactggtg
     4261 ccctggcagc cgctgcaggt ggttttacta ctgtcgtcat gatggctaat accagtccaa
     4321 ccatttcaga cgtggagact ttgcaagcag ttctccagtc agctgccaaa gagaagatta
     4381 atgtcaagac agttgcgacc attactaaaa actttaatgg taaaaacttg actgacttta
     4441 aggcgctctt agaagctggt gcggttggtt tctctgatga cggtattccg cttgagagca
     4501 gtaagattgt caaggaagcc atggaggaag ccaaaaaact caataccttt atcagccttc
     4561 atgaggaaga tccaggtttg aacggtgttc ttggctttaa tgaaaatatt gctagagaac
     4621 atttccatat ctgcggtgct actggggtgg ctgagtacgc tatgatggcg cgtgatgtca
     4681 tgattgccta tgcaactaaa gcccatgttc acatccagca tttgtctaag gaagaaagtg
     4741 ttaaagtagt ggagtttgct caggggttag gtgcagaagt cacagcagaa gtagcgccac
     4801 agcatttctc taagacagaa gcacttcttt taacacaagg tagcaatgct aagatgaatc
     4861 caccgcttcg tttggaatca gaccgtcgtg ccgttatcga aggtctcaaa tcaggtgtca
     4921 tcacagttat tgcgactgac cacgcgcctc atcatgtaga tgaaaaaaat gttgaggata
     4981 ttaccaaagc gccatctggt atgactggct tagaaacatc cctgtctctc ggcttgacct
     5041 atttagtaga agctggtgag ttgagcttga tggaattact tgaaaaaatg acatacaacc
     5101 cagccaagct ttacaacttt gaagcaggtt acttggctga gaatggtcca gcagatatca
     5161 ctatttttga tgccaaggct gaccgccttg tggactccca ttttgcttcc aaagcagcta
     5221 attcaccatt catcggtgaa accttaaaag ggcaggttaa atataccatc tgtaagggac
     5281 aaatcgtcta tcaagcttga taggagttag aatatgaatt attttcgaaa acgtagggag
     5341 agacaagcga aatctaatag tggaatttac tgtcccgcag ctaatcgttc caaaattcaa
     5401 tatgaaacta aagaaaaagc tgaccatgcg gttcaatatg ataacggagg tttagttaga
     5461 agctattatt gtcgtacatg tgcgtgttgg catactactt caaaatctaa taaacctccg
     5521 ctaagtttga aaaactatgg tctgaaactc tttggtttag ataaatcaga atagaaagag
     5581 aagtatgtat aagacaaagt gtttacgaga gaagttagta ttatttttaa aaattttctt
     5641 cccaatcctg atctaccaat ttgccaatta ttctgcctct tttgttgata ctgcaatgac
     5701 aggtcaatac aacactatgg acttggctgg tgtatctatg gcaaccagta tctggaatcc
     5761 tttctttaca tttctaacag ggattgtgtc agccttggtg cctatcattg gtcaccatct
     5821 tggtcgaggc aaaaaggaag aagttgcgtc tgatttttac caatttattt atttggcctt
     5881 gggcctatct gtggtcttgc tggggatggt acttttcttg gcaccaacaa tcttgaatca
     5941 tattgggtta gaagcagcag tagcggcagt agcggttcgc tatctttggt ttttatctat
     6001 cgggattatc cccttgttgc tctttagcgt cattcgttcc ttgctggatt cgctgggctt
     6061 gaccaaactg tccatgtacc tcatgctttt gttactccct ctcaatagcg gatttaacta
     6121 tctcttgatt tacggtgcct ttggtgttcc agaactggga ggggctggtg ctggtttagg
     6181 aacatccttg gcctactggg tcttgcttgg gatttctgtt ctggttttat ttaaacagga
     6241 gaagctcaaa gccttacacc ttgagaaacg aattccactt aatatggata aaattaagga
     6301 aggagttcgt ttaggtctgc ctattggggg aactgtcttc gcggaagtgg ctatcttttc
     6361 agtggttggc ttgattatgg ctaagttttc gtccttgatt atagctagtc accagtcagc
     6421 tatgaacttt tcaagtctta tgtacgcctt tcctatgagt atctcatcgg ctatggctat
     6481 tgtcgtttcc tatgaagtgg gagccaagcg atttgatgat gcgaaaacct atattggtct
     6541 aggaagatgg actgccctca tttttgcggc cttcacctta accttccttt acatttttag
     6601 gggaaatgtg gccagtcttt atggtaacga cccaaaattt atcgatttga cagcgcgttt
     6661 tttaacttat agtcttttct tccagttagc agataccttt gcggcgccgc ttcagggaat
     6721 tttgcggggg tataaggata cagttattcc tttttacctt ggtttgcttg gttattgggg
     6781 cgtagcaatc cctgtggcta cgctatttga ttccctaaca gattttggag cttattctta
     6841 ctggatcggc ttgattatta gtttgattgt gagtggggcg ctctaccgtt ggcgtttaac
     6901 tgtgattatg aagagatttg aatctttagc aaaatccaaa cgctaaaaag tttgtgaaaa
     6961 aatattcttg ataagaaaat cccttgtttt cacggggttt tcttttttat tttgtgaaat
     7021 ttcttttaga aaaactttga cagtatttgc caaaaacggt aaaatagtaa ggtaagaaga
     7081 aagttagaaa ggcaagaaga tgtcaacttt agataaaaat cttttgctag aaatgttccg
     7141 taagatggaa gaaatccgtc gcatggactt aaaaattgca caattagtaa agaaagggaa
     7201 agtgccagga atgacgcact tttctgttgg tgaagaggca gctaacgtgg gggctatgtt
     7261 agctctcaat ccagatgatc tgattacctc aaaccaccgt ggacacgggc aagctattgc
     7321 taaagggatc gacctcaacg gaatgatggc tgaaatcctt ggtaaataca ctggaacctg
     7381 taaagggaaa ggtggatcta tgcatatcgc tgaccttgat gctgggaacc ttggtgccaa
     7441 tggtatcgta ggtggtggta tggggatcgc tgtcggtgca gccctcagtc agcaaatgca
     7501 aaataccggt aaaatcgttg tctgcttctt tggagatggt gcgaccaatg aaggtgtttt
     7561 ccacgaagca gtgaacatgg cttctatctg gaacctgcca gtcattttct attgcattaa
     7621 caacggttac ggtatctctg cggatatcaa gaaaatgacc aatatagaac atatccatca
     7681 acgtagcgcc gcttatggaa ttcctggaat gttcatcgaa gacggtaaca atgtcatcga
     7741 tgtctatgaa ggatttcaga aagctgtaga ccatgttcgc agtggcaatg gtccagtctt
     7801 gattgaaagt gtaacttatc gctggctcgg tcactcatca tctgaccctg gtaaatatcg
     7861 tacgcgtgaa gaagtggaat tgtggaaaca aaaagatcca atcgaaaacc tccgcaatta
     7921 ccttattgaa aataacattg caagtgccga agaattggaa gaaatccaag cgcaagtaaa
     7981 ggaagcagta gaagcttctg ttaaatttgc agaggaaagc ccattcccac cgcttgaatc
     8041 agcctttgaa gatatttacg cagactaagg agaaagagat aaaatggaaa caaaaacaat
     8101 gtccttccgt gacaccatta tccttgctat gtctgaggaa atgcgtcgcg atgaaaatgt
     8161 gttcttgatg ggagaagacg tcggtgtctt cggaggagac ttcggtactt ctgttggaat
     8221 gcttgaagaa tttggtccag aacgcgtccg tgactgtccg atttctgaag ctgccatctc
     8281 tggagcagca gcaggagcag ccatgacagg acttcgtcca atcgtcgata tgaccttcat
     8341 ggacttctct gttattgcca tggacaatat cgtcaaccaa gctgctaaaa cacgttacat
     8401 gtttggtggt aaaggtcagg ttccaatgac tgttcgttgt gcagctggta acggagttgg
     8461 ctctgccgcc cagcactcac aatctctaga gtcttggttt actcacattc caggacttaa
     8521 ggttgtggca cctggaacac ctgcggacat gaaaggcctg cttaagtctt ctatccgtga
     8581 taaaaaccca gttattatac ttgagtacaa gtcagaattt aaccaaaaag gggaagtgcc
     8641 agttgatcca gactacacaa ttccacttgg ggttggtgaa atcaaacgcc aaggaacgga
     8701 tgtaacagtt gttacttatg gaaaaatgct tcgccgtgtg gttcaagctg ctgaagaatt
     8761 agcagaagaa ggaatttcag ttgaaattgt tgacccacgt acccttgttc cgcttgataa
     8821 ggatatcatc ataaactcag tgaagaagac tggtaaggtt gttctggtca acgatgccca
     8881 caaaacaagt ggctatatca gtgaaatttc agctattatt tcagaatcag aagcatttga
     8941 ctatctagat gcaccaatcc gccgttgtgc aggagaagat gtgccgatgc cttatgcaca
     9001 aaacctagaa aatgcaatga ttccaacagt tgaaagtatc aaagatgcaa tccgaaaaac
     9061 ttataacaaa gaatagagtt acataagata agttatgtaa ataaaataaa gctgacgaga
     9121 aactttgtat cttttaggtg cagagctctt cgtcattaat atcttatatt cgagcacggg
     9181 ctaaaagctc ggaaaaaaga taaatctcct tggcttcatc gaagccatcg tcgatttcct
     9241 atttttcagt cgcttttgac gccctttgta tcataaatag aattggagag gtcatggctg
     9301 atgacaagct aagagcgact cctgcagcta gaaagttagc ggatgattta gggataaacc
     9361 tctacgacgt ttctggctca ggtgcaaacg gtcgtgtcca caaagaagac gtggaaactt
     9421 ataaagacac aaacgtggtt cgcatttcgc cacttgcaaa acgaattgcc ctcgaacata
     9481 acattgcttg gcaggaaatc caaggaaccg gtcatcgtgg taaaatcatg aagaaggatg
     9541 ttttggccct gcttcctgaa aatatcgaaa acgatagcat caaatctcct gctcagattg
     9601 aaaaagtgga agaagtccct gataacgtaa caccatatgg tgaaatcgag cgtattccaa
     9661 tgacaccaat gcgtaaggtt attgcccaac gcatggttga atcttacttg actgcgccaa
     9721 ccttcaccct caactatgaa gttgatatga ctgaaatgtt ggctcttcgt aagaaggttc
     9781 ttgagccaat catggaagca actgggaaga agactactgt aacagacctt ctttcgcttg
     9841 cagttgttaa gactcttatg aaacacccat acatcaacgc ttcattgaca gaagatggca
     9901 agactattat cactcacaac tatgtcaatc ttgccatggc agttgggatg gataatggat
     9961 tgatgacacc tgttgtttac aatgctgaga agatgagtct ttcagaacta gttgtagcct
    10021 ttaaggatgt tattggccgt accttggatg gtaaattggc tccaagtgag ttacaaaatt
    10081 caacattcac aatcagtaat ttgggaatgt ttggtgttca gtcctttggc ccgattatta
    10141 accaacccaa ctcagctatc cttggtgtca gttcgacaat cgagaagcca gttgtcgtca
    10201 atggtgaaat tgtgattcgc ccaatcatga gtttaggatt aaccattgac caccgtgtcg
    10261 tagatggtat ggctggtgct aagtttatga aggacttgaa agagttgatt gaaaccccaa
    10321 tctcaatgtt gatttaagag caagagtatt catttttaag atatagataa aggaaggaag
    10381 acatggcctt agaaataatt atgccaaaag ccggcgtgga tatgacagaa ggacaaatcg
    10441 tccaatggaa taaaaaagtc ggagaatttg taaaagaagg agaaatcctt ttggaaatca
    10501 tgactgataa agtcagcatg gaattggaag ccgaagaaga tgggtacttg attgccattc
    10561 tcaaaggaga tggtgaaact gtccctgtaa cggaaattat cggttacctt ggtgaagaaa
    10621 gggaaaacat cccaacagct ggagcagcat cgccagaagc tagccctgta cctgtagcaa
    10681 gtacctcaaa cgatgatggt aagagcgatg atgcttttga tatcgttgtg attggtggag
    10741 gtcctgctgg ttatgttgca gccattaaag ctgcccaact cggcggtaag gttgcccttg
    10801 ttgagaaatc tgaacttggt ggaacctgct taaaccgtgg atgtattcca accaagacct
    10861 accttcataa cgctgaaatt attgaaaata tcggtcatgc tgcaaatcgt ggtatcgtga
    10921 ttgaaaatcc taacttcact gttgatatgg aaaaactttt agaaactaaa tctaaagttg
    10981 ttaatactct tgttggtggt gttgcaggac ttcttcgtag ctacggagtt actgttcata
    11041 aaggaattgg tacaatcact aaagacaaga acgtcttggt aaatggttct gaattgcttg
    11101 aaaccaagaa aatcattctt gctggtggtt caaaagtcag caagatcaac gtccctggta
    11161 tgcaatctcc acttgtcatg actagtgatg acattcttga aatgaacgaa gtgccagaaa
    11221 gccttgttat catcggtggt ggagttgtcg gtatcgaact cggtcaggcc ttcatgacat
    11281 ttggttcaaa agtgactgtt atcgaaatga tggaccgtat agttccagct atggatgcgg
    11341 aagtttctaa gaaccttcgc ttgatccttg agcgtaaagg aatgaccatc ttgactggta
    11401 ctaaactgca agaaatcatt gaggaaaatg gtcaacttcg tatcaaggtt gaaggaaaag
    11461 acgatatcat cgcaagcaaa gctcttcttt caattggtcg tatgccagac cttgaaggta
    11521 ttggagaggt tgagtttgaa ttggatcgtg gttgtatcaa ggtcaacgaa tacatggaaa
    11581 cttcagttcc aggcatttat gcaccaggtg acatcaacgg tactaagatg ttggctcacg
    11641 cagctttccg catgggtgaa gtttccgctg aaaatgccct taaaggaaat catgcagttg
    11701 ccaaattgaa tttgactcct gcagccatct acactctccc tgaagtagca gcagtaggtt
    11761 tgacagaaga acaagcccgt gagaaatacg atgttgccat cggtaagttt aactttgctg
    11821 ctaacggtcg tgctattgca tctgacgcag ctcaaggttt cgtaaaagtt atcgctgata
    11881 agaaatacgg agaaatcatt ggtgtacaca ttattggtcc tgcagccgca gaattaataa
    11941 acgaagcatc aagcatcatc gaaatggaaa tcactgttga ggaaatgctg aagaccatcc
    12001 acggacaccc aacttactct gaagtgatgt atgaagcgtt tgcagatgtt ctaggaatgg
    12061 ccatccattc acctaagaaa aaataaaacg aagatagatt agactggaag gttatttcca
    12121 gtctctatca tataaagtaa agggatatca tgaaatacat tatcaatcat tcaaatgaca
    12181 ctgcttttaa tattgccttg gaagaatacg cctttaaaca ccttttggat gaggatcaaa
    12241 tcttcctact ttggattaac aagccatcta tcattgttgg tcgtcaccag aacactatcg
    12301 aagaaatcaa ccgtgattat gttcgcgaaa atggtattga ggtagttcgc cgtattagtg
    12361 gtggtggagc tgtttaccac gatttaaata acctcaacta cacgatcatc tccaaagaag
    12421 atgaaaataa ggcatttgac ttcaagagct tctcaactcc ggttatcaat accctggctc
    12481 aactcggggt taaagctgag ttcacaggtc gtaatgacct tgagattgat ggtaagaagt
    12541 tctgtggcaa tgcccaagcc tatatcaacg gccgtatcat gcaccacggt tgcttgctct
    12601 ttgacgttga tttgtcagtc ctcgcaaatg cccttaaggt ttcaaaagat aaatttgaat
    12661 caaaaggtgt gaaatccgtc cgtgcccgtg taaccaatat tatcaatgaa ttaccaaaaa
    12721 aaatcacagt cgaaaaattc cgtgatttac tcttggaata catgaaaaaa gagtacccag
    12781 agatgactga atacgtcttt tcagaagaag aattggccga aatcaatcac atcaaggata
    12841 ctaagtttgg aacttgggac tggaactatg gtaaatcacc tgaatttaac gtccgtcgtg
    12901 gaaccaaatt cactagtggt aaggttgaag tctttgctaa cgttactgaa tcaaaaatcc
    12961 aagacatcaa gatttatggt gacttctttg gtattgaaga cgttgctgca gtagaagatg
    13021 tccttcgtgg ggtgaaatac gaacgcgaag atgttcttaa ggcgctaaaa accattgata
    13081 tcacacgcta cttcgctggt attagccgtg aagaaatcgc tgaagcggta gttggataaa
    13141 tcaaaaaaag aagttggcca acttcttttt ttgatattta tttacataat ttaaaatacg
    13201 tgaaatcata aactatctag agcattcttt tgttcatcat taacaatatg ggtatagagg
    13261 tcagtgactt gtgtgctggc atgtcctagt tggtgactga ctaaaacttg tgatttagtc
    13321 gcatcataga gcctagttgc tagcgtatgg cgcagtttat ggggtgttac acgtacttta
    13381 aaatcctctg agtatttagc aaccattttc tcaacgctag aagcatcgat acgattagga
    13441 acacctctgt agagagttaa aaaaagggct gtatctgttt tttccgtttt atagcgttga
    13501 ttccgaatgg ccagataatt ctctaaataa ggtttagcaa aagcagcgac attgactgag
    13561 tcacgtttgc caccttttcg agtaacatca ataaccatca tttttagatt gagatctctt
    13621 agatctagat taacagcttc agataagcga acaccagatg ccaagagaag ggcaataatg
    13681 gctaaatctc gttctttatt tttgttgaat gatgagagag ctcgatttga aagctgttgt
    13741 gggtgctctt gatcgatata agttagaaaa ccttctgttt catcacctag aaagagtttt
    13801 tgcttgatat tttcagctct ggcagcaagg gtttctttct ttttcttggt tgaaactttt
    13861 ttcattacat tacgatagaa ataaggttcc ccctgatcgt tttcaacctc ctcggttaga
    13921 tacttgtaaa gactagaaag tgctgataag gttcgattga tagttgtctg tgaaacacct
    13981 tgttttgttg tattagcatt cagcaaggga cgttcacgta gataaaggat aaaggattcc
    14041 atgtctttct tagacatatt ttccaaaact gataaaggaa tatcggatat tttatcagcg
    14101 tttgaaatac cagactccaa aacccagctg aaaaatcggt catattcctt aaggtattcg
    14161 tacagggttg taaaactgta gggcacagcc agcttagatt ggtagtattc cagaacatac
    14221 cagggcatga gttgttttag tttgtcgatt cgttccagta aaatctcacg tttcatgtat
    14281 tttctccata agtaagtata ctagtagtat agcatagact tgtatatttt tcaagaaaat
    14341 tatagttttt cagaaagatg ttataggagt ttttcaaagt gataaaaaga cttagaccta
    14401 caaacaaaac agaataagga aaataataaa aatctcaccc actaaacttc tgttaatact
    14461 acataactga agagctatat aaggagctat gagatacaaa acacattgta taatagattg
    14521 aaactagaat agtacatctg gacttctaaa acattgctag aaattgattt gattgttctg
    14581 attgttttat cctatttcta tttcatttca ctatataatt gctattgttt tctttttcat
    14641 gattttaatc ttactgtaca gatttgatac agtaaactcc tttctagctt tatactttat
    14701 catttctaac ttaattatag tcttattttt aataaagttc aattatttat atgtaaaatt
    14761 cctcatcagt aaaaaataac cgatctcatt tctgagaatc ggttttctaa ataaatcaag
    14821 ctgagtattt acataacata aattatgtaa atactcatac tacaacaaca aatctttgac
    14881 ttttccaatt tcactttttg gaataaccag gtgaatcata tcacccagat acattctggt
    14941 tgagccgtta actgtttggc tcttgccatt atggacttga gttgtgatga ggacgttgtg
    15001 tggtaagttg agttcatgaa cttgtttccc agcaatttta tcagaaactg gtatttcgat
    15061 aagtgtaact tctccttcgc tagatacttc ttctggaagc attttttcca gcatggcttc
    15121 atagactggc gtacctttga gcaaatccat gataatataa gaaacaagag tgacaagacc
    15181 aagtggcatg aggttgcgaa tatctcctac catctcagtt acgaggatca tagcggttaa
    15241 gggagctttt gatatggctc caaaatagcc actcattcct agaatgacaa atatagggaa
    15301 ttgctcttga ctgacaagtc caagattgac acagataaca ccaactaagg aaccaagcaa
    15361 agaaccaaga gctaaaatgg ggaggaaaat tcctcctggc agtccacttc catagctaat
    15421 catactccaa ataaagcgga tcaaaaagta agctaataaa acttggaaac taaaattttg
    15481 ttcagttaaa gaaaggacaa gctgatttcc gccaccaatg atttgaggta agaagattcc
    15541 gactggtatg ataatgataa aagccaagat gggataataa gccctatcca aatggatttt
    15601 ttgaccaatc aagtcataaa ctcttccaac gtttaataca gctttctcat agagaaaacc
    15661 tgaaaatcca aggaaaattc ccatgacgag atatatccaa tactggtcta gggtcatggg
    15721 aggaatgtta tctggcatat ccaatactgg tgtcaaaccg aacatgagta gagacacaaa
    15781 gtttgctacg atgctggctg ctagagttga gacccagaaa aagcgcgaaa aatggtgata
    15841 gacttcttct acaacaaaga gaagtgctgc aataggagca ttaaaggctg cggctaaacc
    15901 tgctgcagct ccactggcaa tcaaggaacg ttcctctact ggactggatt tgagccactt
    15961 ggcaattcct ttaccaccaa ctgctccaag ttgaatgctg ggtccctctc gacccagcat
    16021 gagtccactg gcaatagcaa gaatacctag cacatatttt ttccaaagaa tgccccacca
    16081 gttgagggac atgaggcctt tcagttcggc ttcgacttga ggaattcctg agcctttaat
    16141 atctttttct gaccgtgtta gtttggcact gagccaacag atgagtatat aaaacaaaac
    16201 cagtacaaaa agattgcgca ctaagtaccc ttgatcttga taaactcctt gtatcaggtg
    16261 gaagcccttt tcaattaaga aacgaaagga tccgacgata attccaacga tgaggccgac
    16321 aatgattcct cgaccaactt gggatagtat agtgctggat gcaaaggcga attctttctt
    16381 agaacggact atttccgact gttcctccat ggtatttcct ttcaattaac tttctttttt
    16441 acctaaaacc agtgatttaa cgggttcaaa gctggttcgg tgaattgggg taactcctag
    16501 ttttgtgagg ccttccagat gtttagctgt gccatatcct gcattagtag cgaaatcata
    16561 gccagggaac tgctgatcgt attccttcat caattcatca cgtgttacct tggctactat
    16621 agatgctgct gcgatagaga gggagttggc atctcctttg ataatggagg tttgtgaaat
    16681 gggcaagtcc agtttcatgg catcaatcaa aaggtgctct ggttgagggc tgagctggga
    16741 gattgcttct tgcatggcta gtttggttgc ttcatagata ttgacttggt cgatgacctg
    16801 attatctatg ataccaattc caatcgacaa ggcttggtct tgaacgactt ggaaaatctc
    16861 cagatgtttc tttttaggaa ttttcttgct gtcgttgaga cctttaatct tacaattttt
    16921 aggtaaaata acggccgcag cgactacagg accagcaaga ggaccacgac caacctcatc
    16981 aatacctgca attaaggtca atccttgctt ataaagttct ttttcataag aaagcatgga
    17041 ttccaagcgc aaattttcat ctaattcagc ttgaatggct cttttatgct tgctgatttc
    17101 cttttgaact cctgagcgat tatccttttc aagatctaaa aaaatagggc tttctaactc
    17161 cttgactgtc acaaggagtt ctttgatttc tttaatcgtt gccatcgagg ccttccaatg
    17221 tatctaaggt atagttaccg agtttgccat cacggacttc cttcacgaag agactgtaaa
    17281 aacggtcata gtcatcacgg aaaccgaggg cgcgggtcat atccataata atcacaggcg
    17341 cttcttcttc aattttcatt tgtttgaagc gttcagccag cttttctgga taatgttctt
    17401 tgaaataatt gataccaaaa atggtaacct catccatagg aagcaactga tccttgatag
    17461 ctccagtcaa tgccaactta agtgcaacag tttcatcctc aaacttaggc cagagaatcc
    17521 ccggtgtatc caagatttcc agatctttat tggttttaag ccattgttga ccttttgtga
    17581 cccctggctt gtttccaaca acagcaatct ttttaccagc caaacggttc atcagagttg
    17641 atttaccagc gtttggaatc ccaataatca tggtacgcaa ggtttcaatc tgaatcccac
    17701 gttctttctg gcgagcaatc ttatcagcca tgagcttctt ggccgcatct gttacaactt
    17761 ttacagtcac ttgctctttg gagttgatag ctagcgtctg gattccttgt gattcaaaat
    17821 actgacgcca ttccttggtc attgctggat cagccaagtc ggccttgttt aaaatcaaga
    17881 gttttggttt atcaccaaca atcttggtta acataggatt ttgactagat agaggtaagc
    17941 gtgcatcaac taaaatcgtc acaaaatcaa caaattttaa attctcctgc acctgtcgac
    18001 gagctttaga catgtgacca ggaaaccatt gaatagtagc cattgagttt tttcctttca
    18061 tagcaaggat ttagatcccc tattttattt tactattgtt tgaacataga gagttttcaa
    18121 atgaatgatg tccaaacagt tcttgtttta tgacatagaa atctacttta tattatatca
    18181 tgccttcttt attttgtccg atgatagcct tttaccctat atagaaaaaa gccatcaaat
    18241 gatgactttt cagagggagc aaaaaactgt tcccgtcata ttatgaacca aaagaactaa
    18301 actaccaaca gctaataggc ctaaagctgt aagtgcagaa gttgatgaac ctgttgcagg
    18361 aagagtttcc tgctgataaa taagagcata acttacttca ttatcagtag gaattcctgc
    18421 ttgaatcttg gtttgttctt catcaccttt ttaaacttta tttcctaata gtaaacacta
    18481 ttttttattc tcaaaaattg aacttctaaa atcatttgtt tggtcaagat aggctttaaa
    18541 gattgctctc ttcaacttat gaacggcact gtcgatttct ggatcataat tactccaacg
    18601 tggaccttca gcatccttga gaacagcttg gtccatgagg gcttgcaatt catccacatt
    18661 attgatagtc tttgtgccat agcttggcca tggttttgtc ggatctttaa aggtcacctg
    18721 cttcaagttt ccaaactgat ccactcgttc ttggtacata gctgtcttaa attctgccca
    18781 agttttatac ttaccgtcaa ataccttttt caaaacaagc tcatcggtca ccaagccccg
    18841 ttctttacca taaagattga tagtttgccc ttgttgttta gcatcttctt cgtattggtt
    18901 tgagatataa ggtaccattc catccttaaa gcctttggca gccaaaagtt cgtacgcaat
    18961 cctacgtccc ataaggtccc ctggtgtgcc tttctcactg ctgagagctg aatagattgg
    19021 ggcaaagagt ttgatggtat agtagccatt tcgttcatag tcgccagact ggtactcacg
    19081 agctgataag atgttgtggt caatcaaact ttcaaaacta ttcaggtttc gggcctctgc
    19141 ttctgtcaat tctttgacta cgttagtggc ataaacctca tttccatctg ctggatcttt
    19201 cacatacttg ttctcaattt ttctgagagc cgccattttc tggtaaacac ttagtttatt
    19261 aacgattgac tgcccttcga gatattccat catgtagata aggtcaaaca tgttatggac
    19321 atagttctga agatctgctg cgttttggaa tctctctgtc ggatccaaga cttgaagacg
    19381 ggatccctct gtactatctg attttgagtg tttcaagata gaattaatgg taatggttgc
    19441 gtcacttggt tggtcagggg cttgcaataa gccttttgcg aagaactctg gtcccaagcc
    19501 atttcttcga ccatagccac caaggtaaat atcctgatcc gaatcatggg tcatttcatg
    19561 ggtataagta atggctccat ccttgtccag catgcggtaa gacatatagt agacgccgtc
    19621 ccctgtagcg taggctccat gctggttgtg tactacctta ttgccaactg gtccaaagaa
    19681 gttcttcata gctggattgg agctatcaaa cttagcctcc gctgtagctt ttcctgatgt
    19741 tgtgtcatcc ccaaacttat aggcatcata aaggagaatc gtacgataga gtttttcgcg
    19801 tgactgttca tctaaaatac gataccaata atcgtagtga tctcgctgac gtttggctgt
    19861 ttcacgcgca ttttcttcaa caaaatcatt gagagccttg cccgctttat ggtcactact
    19921 gcggtagcga tcataagctc caaatcctag actagacatg gtcgagatga caaatacgga
    19981 tctctctggc aaggtcagga gaggcaagac catattgcgg tatttccatg tggcactcgt
    20041 gatacgatca taaacaccga tagaatactt ggtgccagct aacccttgct tcgttttcac
    20101 ctcttcgata gtggattttt cttcgacaat gtaagcctta gtctctgatt taaaccagtc
    20161 attattgctt gtatttggta aaaagacttt tcggtaatgt tccagcgtgc taaacaaatc
    20221 tgtcgttcca tgttgactgg caagactgat accataagta tcgacattat tcttagctag
    20281 aagattgtta aagccagatt tacctaactc aatcagagta tctagtgggg aagtatttcc
    20341 tttaccaaag aagtctggat gatacataac taggtctttg acattcactt gaccatagtt
    20401 aaagttatac caacgttcta aataagttaa accgagtagc aaggcttcct tattattctt
    20461 gattttatct acaagatagc ctctggtgac tgagttatcg ctagctagac cggcatctgc
    20521 tgacaaaagt tttttcaagc tgtctcccag attttgtttt gttttggaga actggtcttc
    20581 taaatagagc tcggttaact taacttctgg agaaatacca agtgtctttc tgatagcatc
    20641 tgactggtaa tcaagcttct gcaactcagg caagacttcc ttaacaatag agtctcgatc
    20701 atataagaat tggttaggag tgtagagaag tcccgtatta cctagattat attctgctag
    20761 attggcaaaa tcagtctggt acttgagatc aaatttctca gatgaatggt cattatagtg
    20821 aagtaagagt ttgtttgcag tctgtttgtt ggaaacaata tctgtgatta cttggtcatc
    20881 cttcatcata actgcagata agagttcttt ttggtataag agactgttct ccttaaccag
    20941 gtttccgtat ttgacgatgg ttgacttatt ataaaaaggt aacaattttt caatgttctt
    21001 ataaaccaaa gcacggttag cttgataatg ggctatctta gaaaaatcac tgtctttctt
    21061 gccacttgtt gagaggggtt ccaccgttgg tagagtgaga ggatttattt ctgctttttt
    21121 gcttacaatt tgagaagcat ctagcattgt tcctctttct tcaaaggatt ccttgctgac
    21181 gacctcatcc ttctctaaag tgacattgaa aactctatta gccttactac taaatgtatt
    21241 agctaccttc attcctgtat agtggtatcc agtgatggca tttccgtttg ttacattgac
    21301 atcgctaaga acattggtca attcaccagc gtgtttttcc tcaccagaag ttcgatccca
    21361 caaatatcct gccacaccag cgactttacc aaagtgcttg acattattaa tatcaccttc
    21421 cgcataactg ttctgtatat gcgcatcttg gtctactaga cctgcaagac caccgacagt
    21481 ctgatctgac ctattggtgt ttgacgaaat ggttactgtc gctttggatt tagcaataga
    21541 cgcatttttt cctgttaaat gaccgaccag accgccaata ttgtaggcat cagtcgtttc
    21601 ataggtattg acaattcttc ccttgaaact gctctctgcg atgcttgatt ggtctgcctt
    21661 agccaacaaa ccaccgacac cacgttctcc agccagaaca ccatcaacat gaacttgttt
    21721 aatctttgtg ccattcgtag cttcatttgc tagtgaacca atatcatttt tccctgaaat
    21781 agcaacattt tttagactca gtttttctac tgtagcacca ctcaagtttt caaacagagg
    21841 ttttttcaaa ttatagatag cataattctt gccatctttt tcaccgatta aacgaccagt
    21901 aaaggtgtcc ttgatatagg atctttcatc aggaccaagc tccacttcgt tagcattcag
    21961 gctggccgct aaatgatagg ttccagaggg attttggttt atagctttga ccaggttgct
    22021 aaaggaagta aagtttgtat tttcctcttt agccttctta tcgaggtaga aggtgaaatt
    22081 gtcgacatat ttattttcta gttcttgctg gagtttctca gctttggctg tgattttata
    22141 aactgactgc ccatttcttt tctcttcagt tattgaagct actggtatat agacatcttt
    22201 aaatgctgaa gattttacct tgacaaagta agtatccgta ttctctggaa ttccatccaa
    22261 tgaaacatgt tgtctgtagg ttccattcgt ctgactatac aactcaatat cagaaacatt
    22321 tcttaattcg agttttttct ctggttctgt ttgtccattc tctgatgttg tattacctga
    22381 attttctggt tttgttgcag ttccgttttt ttctggttga tttgattctt caactggtgg
    22441 ttttgaatca ctaggtttat tggatacttc tccagtattt tcgttagcta ttttcccaga
    22501 gtttgtttgt gtttcttctg caggttgaac tggtttttct gtttcttgat ttgaggtacc
    22561 ttctactgtg ccttcatttg gatttactgg aacttcttct acagtttttt ctgaattttc
    22621 atttttagag tcattatgtt ctggtttatt tgattctcca actgaggttg tcgaatcact
    22681 aggattactg gacacttccc cagtattttc gctagatgta tctggtgata ctttctctga
    22741 attcgttgtt gattcttctg caggttgaac tggattttct gcttcttgaa ttgaggttcc
    22801 ttctgtagta ccttcatttg gatttactgg tgtttcttct gttggtttta ctggaacttc
    22861 ttcagttttt tctggacctt gttctttggt cttctcaacc ggagtttcag gttttacttg
    22921 ctcaatatta cccttatatt ctggcaatgg ggctacctgc tctggttcac ctttatcact
    22981 taccacagta tctggcgact ctggttgaac ctcagtctca cctttgtcgg tcacaactgc
    23041 ttcgggtaat gtcggttgaa cttctggttc gcctttatca cttactacag cttcgggcaa
    23101 ctcaggctga attgcgggtt caacaataga tccagactgt acgtccttat gttctacacc
    23161 agtctcaggt tgttccttta taacttgagt ttttttagta cctttttcga ctattcttgg
    23221 actaggcgca gtcgttgaag ttgaaacaat ttctcgcgaa acttcttcct tgtttacaga
    23281 gaatattctg acgatttcaa ctttcttacc taatttacct tcttgtttta ctcttacagt
    23341 tccttcagct aaatcaggat tttcttgaat ttcttcttga aaatctattt ttgtctctat
    23401 agtttcctca cgatataaga gttcaggttt gttcaattga cctgataaaa cttcatcctg
    23461 tggatttaat gtatttaccc cagtcttttc ttttggagaa atcttctcct ctttcttcgt
    23521 ttctagattc ttatgttcgg ctaattgttc ttgagaatct gaagattgtt tctcttcttt
    23581 tcttggattg attaattcag tagagaaagg tttttcaact acttgaactt ctgtcggctt
    23641 agttgaagaa acaggtgttt gttcctgaat agcttgtact gttgatggat ggtctacaaa
    23701 atttggtgta acattataat ccaccttttg ttgttttgta ggagtggctg ctgatttttc
    23761 ttgattactt acttcaaaat cagaagtcgt ttttccctct ttgatatatc caatataagt
    23821 gtaacctgaa atctctttag gaagaggtaa tttttctcca gaggtcaatt catagtccgt
    23881 attgtaattt agcaaaagat gattttctaa agcatggact gaaactaaga caccatttcc
    23941 cattcccgca accaatacta aatgtaatac cgttttattc ttaacctttt tcttggaaac
    24001 agcaaaaatt aaaattccca gagcagctaa gctagcacca gcaactaggg cttgcctctc
    24061 attcttgctt ccagtatttg gtaattccgc cagttgattt tgagaattta acttataaac
    24121 aagataataa gtttcatcat cattctccac gtatgtcgga atatcataga caagctgctt
    24181 cttttcttct gatgatagct ctgaatctgc cacatattta tagtgaactc ccgcagtttc
    24241 ttgagcatcc acagatgaac tagctaatac agacataaaa aataaacttg aaatcgttgc
    24301 agatacaagt cctactgata attttctaaa tgaaaaacgc tcttgttttt caccaaaata
    24361 cttttccatt attcctcctt gaaataaaat ttatatatgt tacaaagacc tttattatat
    24421 tagtgtatta tctattatct atagaaaagg cagtatacct taattatact cttaatttac
    24481 aaaaaagtct taaaattgag atgcgctttc atactttgtt ttatattatt tgggggtaca
    24541 ataacaccta ccatgaaatt tacacggtag gtgttactca tatcactaat cgttctaaaa
    24601 atggtttgag gcagttgagg agaattcctt ctatccagct tccttgtgct gatgagcgat
    24661 ggtcttcctg caggcttttt tttagaaaat ctcggacttg ttctggtgcg atttcaaatt
    24721 caaaggcttt cattttatag aaaaagtcga tgagatgatc tgacaggtat tcagttgaaa
    24781 agggtacttc accacttttt cgatattcta ataagagtct agaaaatcga gctttttctt
    24841 caggaagctc acgaaaatag gaattgagga tccaagtctg cttctgtttt ctttcaattg
    24901 gatcctgact ggcaattcgt tggtcttttt ccagctcttt ttggtattgt ttggccttga
    24961 tagctcgttc tgctctattt ttaccaaaaa gaattttttc ccacttgcgt tcttcttgag
    25021 tcagggtctc tgtaaagcca aagtaatctt gataagcacg ctctgcgggt cccatggcta
    25081 gaaccagatt gtctgcatat tgcttggcga ttttatccct cttcttgcgt tctttctctg
    25141 cctggatacg gagttcttgt tcgtagtcaa ttttctcctt gcctagcttg acaaggtaga
    25201 gttggtcatc cgatttccca agtaaaaagg gtttgataca cttttcaagg acttcttcca
    25261 tccgagcctt tttctttggt tccgccttgg tccaacttcc tccctgaaag acttctagga
    25321 aaagctggta gtctctctca ggcgcaaatt gattgccacg attgggtttg aaaacacctt
    25381 tttcccagag ccattttaga agtcgctcgt caaagtcact tttattgacc ttgatttttt
    25441 cctttttctg agcttttctg gttagatttt caacctttct gagcagtttt tcttcctctt
    25501 ccaattgctg gtcaaggggc aatcgatgaa aatgacgaac acagtcgcta ccaattggaa
    25561 agaggcgttg gcctgtgaca ccgttaaaga gttcataagc gtatttgatg gcatttcgac
    25621 agacacaatt gctacggcca ataccgttaa aaatcaagga aacttcattc cattccttgg
    25681 tagcttgttc ccaagtatcc gctttcgaag cctgtaaaac tgcatcgtgc agggattttc
    25741 taactggaag tgtcatgagg tctcctttct aatactcaat aaaaatcaaa gagcaaacta
    25801 gaaagctagc cgcagtcagc tcaaaacact gttttgaggt tgtagataga actgacgaag
    25861 tcagtaacca tatatacagc aaggcgaagc tgacgtggtt tgaagagatt ttcgaagagt
    25921 ataagttata cttttacaac ttgaacctcg tctttaccga gtaaaatcaa gtatttttca
    25981 atattttcaa tcgaataggc tcgtgataaa gcctcttcgt atagagctaa ctgaccacga
    26041 tagcggtcta cgagttgact tggttcatca tagcggtctg tcttgtagtc gaacagaaca
    26101 attttgtttt cgtaaagcag atagccatca aggataccac ggacaacaaa gtcttcctga
    26161 ctcttttggt ctcgtttgag catggagaaa ggttgctcgc gatagagatg gtcggtatta
    26221 gcaagaattt cctgaccgag tgctgtgtca aagaaagcaa gaattttatc aagattgatc
    26281 ttgtctctga cagcttggct agtttgaact tgtttgagtg tttctgttaa gctagcaagg
    26341 gttagttgct ggctgaggtc aattatctgc atgagttcgt gagtagcact accaatctca
    26401 gctccagtta ccttttcttt ggttgaaaaa tctggcaaat cgaagctgat tttcttgcct
    26461 actgactgac cttgaccagc aatctcgaca ccttccatat ccataactgg ttcgtagaat
    26521 ttcttgattt gacttggggt ttgaacacta ggaagttcaa tagctgcgcg gtgaagagta
    26581 ttataaactt ccacctcctt cagcatttcc agagcttctt tgatggtatc tgactgacga
    26641 ttgtctgctt gggagctatc ttggagagga ctcttggttt ccaactctcc gatagcttct
    26701 ctggtcaact gatcttcgtc aataaaacga taactaaagt tgagcttgtc cttagtaaac
    26761 actttactga tagcccaaag ccaatcttgg aaattccgtg cttgcagtct agtattgcta
    26821 tttagtttcc catttttggc tgctgggtat tccttggatt ccagcttttc acgagaaccc
    26881 ttgccgacaa gatagagctt tttctcagcc cgcgtcatag caacatacag caaacgcatc
    26941 tgctcagaat agcttgctag ctgtaattcc tcttcgttct gcctataggt cagactagga
    27001 atggagagtt tgatggtttt aggatagtgg tcttctactg cccctgtctc catcttggca
    27061 atatatttga caccaagacc attctgacga ctgagaatga cttctgacat agagtcttgc
    27121 ttgttgaaat cttgatccat attgaggata aagacgtaag gaaactccag ccctttactc
    27181 ttgtggatgg tcatgagctc tactgcatct tttggcggtg cgacggccac gcttgccaaa
    27241 tcgtgctggg cttctaagac ttggtcaatc atacgaataa aacgcgacaa acctttgaaa
    27301 ttgctctttt caaattgatc agcacgcagt gctagggcat agagattggc ctgcctagca
    27361 ggaccattcg gcaaagcccc aacatagtca taataaaaac ggtcgttgta aatcttccaa
    27421 atcaagtcat agagagagtg ggttttggca tacaagcgcc aagaagctag gatatccatg
    27481 aattgcttta gtttttcaac tagagctgtg tgaatcaagc ctttttgact acttgccatt
    27541 ttttgtgcat tgaccagttt ctcatagaga ttttcgtgga ctttatcctc tgctttctga
    27601 agggacaaac gtgctagctc atcctcatca aaaccaaaca ttggagactt cataagggca
    27661 accaaggcgt agtcttgcag gggattgtga atgacacgaa gagtgtctag catgacttgc
    27721 acttctaggg attggagata attgttttgc tctccgtcag ttttgacagg aatcccgtac
    27781 tcagacaggg cgaggagaat ctggtcatta cgactgcggc tggaggtcag aagggcaatt
    27841 tccttaaagg caacaccttt ttcttgatga agtttcagaa tctccttgat aactaagcgc
    27901 atttcgcctg ttagtttcgt ttctgtttga ctctcttctt cctcacctgt atcgtccttg
    27961 tcgtagagga gaaattctgc cttgttgtct ggattgggag tcagtttggt attggcaaaa
    28021 acaagctggt gcttgttatc atagttgatt tcaccgacct cttggtccat gagacgttca
    28081 aagacatcat tggttgctga cagcacttct gaactactac ggaaattttc cttgaggaga
    28141 atgagcttgc cttcttgggg attttgcgca tagcgttgga atttctcatt gaaaatctgc
    28201 gggtctgcct gacggaaacg atagatggat tgcttgatat ctcccaccat aaagcgattg
    28261 tggccattag acaacaattc cagcatccgt tcttgaatat ggttggtatc ctgatactca
    28321 tcgaccatga cttcatggaa gcgctcctga taagactcac gaacttgtgg gaaattctct
    28381 aaaatctcaa tggtgtaatg gctgatatca gcgaattcaa aggcattttc ctggcgtttg
    28441 cgctgacgat aagcctccac aaaatgactc ataaaggttt ggaaggtttt agctagtttc
    28501 catgtgtctt gatgataacg ttcttgatag tcgagaatgg ttatctggtc tgataattgt
    28561 cctagtttag caaactgggt ctttctctct tcgttgtagg catcagccag gggcttcaaa
    28621 tcagccttac gactggcatt agtcagagct cgaccgtttt tctccttaga gatggcgaca
    28681 acacgcgcaa gcactgcctg ataagcctga ctatcggact cctgatttag ggagcaaatt
    28741 tcatccagaa ttaactgaac attttctaaa taggcagcct ttgcaaactc cttggcatcg
    28801 ttatccagat ggtaacggaa aaagctttcc aaatcccaaa gggcttgttt gatttgctca
    28861 gtcagttttt ctttttcact ggtaaaatca gctttctcaa atcctttgag gaaagattca
    28921 ctcagccact tttgaggatt actggtggat tggaggaagt catagatttt atagacctgc
    28981 tggcgcagac cccgttcgtc cttgccacgc ccagcaaagt ttttcagcaa atgactaaag
    29041 gtctctttct gtttaccttg gtaatgcgct tcaaagacct catgaaagac ttcgttttcg
    29101 agaagaagtt gctcgctttg gttttgtaaa atacggaaat taggtgcaat atcaagcaga
    29161 taaccatgtt tgccaaggaa tttttgtgtg aaagagtcca tggttccgat ggcagcgttt
    29221 ggtaggtctg ccaactggcg tcccaagtgt tgtttgaggt cgacatcatc tgtttcttgg
    29281 attttcttgc tgattttttt ctctaaacgt tctttaagtt cagttgcagc cttgacggta
    29341 aaggttgaga taaagagttg agaaatttcg acaccacgcg ccaattggtc cagaatgcgc
    29401 tctgccatga caaaggtctt tccagaacca gccgatgctg agaccaggat attctgacca
    29461 gaagtgtaga tagcttcgat ttgctcggca gttttctttt gttccttgct cgaatttgct
    29521 tctgcttctt gcagtttttg aatctcctcc tcacttaaaa agggaataag cttcatcgat
    29581 tcaactcctc tcttattttt tcaagccaag cttgcttgag tttttctccg accagacgct
    29641 tgccatcagc taggtccaac ttttctagga aacgggcttg gcccagatgg taattggctt
    29701 caaagcctgt aatagcctga tgttgctgga cgtatggggc aatgcttctg ccattttcag
    29761 tataaggatt gatggcgaac cggcctgcta aaatcttctc agcagctttc ttgtaaagat
    29821 aggcattgta gtccagtagg agctgaaatt cctcatctgt cagttgattc gccttgtttt
    29881 tgttataaaa ttcgcctaaa taactgcttt ctttttccaa gaagagccct tggtatttca
    29941 tagatttgct ggcttctacc actgctcctg ccagactttt taccgccatc agagattgga
    30001 caggttcagc catttccaag tacatggcgc cgaaaaagtt ctgctcccct tctcttttta
    30061 gggcagcaag ataggttggt aactgagaat tgagcccatt aaagaaatga ggaaactgga
    30121 actgagtcag actggatttg tagtctacta ctcctatcgc tccattagct ttcaaacggt
    30181 caatccggtc caccttgcct cgtacaaaga cactgcgtcc attgtctaat tgaataaagg
    30241 cttggtcttt tccaccaaaa tttgcttctt ctttgattgt ttcgatggct ggattgtgtc
    30301 ggagaatatg tccagttgtc cgtgcaacat caagcaaaac ttccttggta aactgggctt
    30361 ccaaactttc ttgataaata gcttcaaatt cgcgttcttg actggtttct tgaatagctt
    30421 gttctagacg ttggtcaaag gaatcttcat taggcaactg caaggcgcgt tcaaagatac
    30481 gatgcaagaa attcccgtga ctacgggcat caggacgcaa acgtaattcc tcctgcaagc
    30541 ctaaaacgta gcgtaggaaa taactgtatt cattgcgata aaactctgtc aaacccgacg
    30601 tagacaggta aaactcctgt ttggcaggat agagagcttg caaggtgtcc ttggctaagg
    30661 tcttgctgct tggactgatt gggatggctg gattttccag accttgctga tctagttttt
    30721 tacctatgac acgcgacaga accttgacaa aagtcaaatc ttgctcagta tcgctcatct
    30781 caccctgctg gtgataggca accagactag acaaaagact gtgataggac cccatatcct
    30841 ccttagacag tcctttgtga ttcatcctct tctctctccg cctaaatcca aaatggatca
    30901 actcttgaag ataggcagat tccttacttt cactttcgtt aaaaaggctt ggagccgaca
    30961 agaacaactg cttacgagca gaattgacca aggaaagcat agtgtagcga tttttcttga
    31021 gattttcact gctggcaatc agtaattgaa cgccttcttc ggtcgtttgg tttaggtttt
    31081 gcctttcttc atctgtcaga agactggtgt tttgagaaat ttttggtaaa ttgtcctgag
    31141 ttagtccaat agcatagaca aagtcagcag tcaatggtgc aatcaaatcg taactctgca
    31201 ccagaacagt gtccactgtt gctggaatgg tacggtattg ggacaaactc attccagaat
    31261 ggagcaaggc taggaagtct tccagactaa cctgtgaacc agcaaaaaca gtcgcaaatt
    31321 gttctaaaac atggcagaaa gccttccaaa cttcggcttg tctttcctgt tctacagctt
    31381 ccaaagtggt tgtcaaatct tgtaactgct tggtcacagc tccttctttt agaaagacac
    31441 tccatttttg taggaggttt tcagcctttt gttttcggct ggcaaagagg gtttcaagag
    31501 gtgctaaaat tctcaggcgg aggacattca aacgctcaag attaaatttt ccatggtggg
    31561 atttggtgaa agtttgctga aaggctggca agccattgat accaagatag cggatatatt
    31621 gctcaaaagc atcaatatca gactgactga ggtcagtata caaatcagtt ctaagaagat
    31681 taatcaaatc ctcctgacga aaacggtaac gttttaaagc taaaatagac tcgacaaact
    31741 gagtcaaggg atgatgagcc atggcttcgc ttctaccaag ataaaaagga atctgatact
    31801 ggtcaaaaat ggttttgaga gataactggt aagaagctac atcccccaag agaatacgaa
    31861 aatgcttgta gctcaggtct gagttctcat gtaatttctg acgaatgcta cgggctacta
    31921 gctccaactc ctccttttgc gtcaaacaag accagatttg taaattttca cggtctttct
    31981 catcgacatc caaagcgagt tctgaaaagt cataagaaga ctccaacaaa cgagaggcct
    32041 tgtcaaaact atccatcttc tcatgagttt gagaacagtc ctgagcaggc gtttggtatt
    32101 tagaagccag atgatggaga aattttacgc tggcttggta gagattgccc tcgctaaaag
    32161 gactggtata ggctttctta ctagcataag ccccgataac aatctcaaca cctttgccgt
    32221 gaagtaagtc cacaacccgc tcttcctcag cagaaaaacg agtaaagccg tcaatgacca
    32281 aggtgatttg attaaaatca ctacttacct tgtcattctc aatagcctca atcaaatggg
    32341 acaactgact tccctgggct aactgacctt gattaagata ggctgttact ttctcaaaaa
    32401 tcaagagtaa atccgccctc ttatcctcat ctgttaaatt ctccaagtcc aaaaaactca
    32461 tctgagattt ggtcatctca tggtaaagct caattaactg ctggatcaat tgaggatcct
    32521 gcttaatagc gccataaaca cgcaagtcct tgggatcgag ttcggcaagg catttgtaaa
    32581 aggccaaccc aagaccgata tcatcaagag tagttttaac tggtaaatca ttcaagacca
    32641 gataacgagc catttgagca aagcgcgtga cggtaatcga aaaagaagcc tgctgggaca
    32701 agcattccag cacggcgcgt tccttttcaa aagaaagaga gttgggggca atgtagaaga
    32761 cccgcttgcc agctgcaact agctcttctg cctctcttgt tagaatttct gtcaaagaag
    32821 ttcgaatatc agtataaagt aatttcatct cagcctcgtt ggaatttttc atcaccctat
    32881 attataccat gattagcctc gtaaatctgt taaaatattt aggccatcct ttcttttctt
    32941 catcatctgc taaatcttaa atacttagct ttacttgtat tagatagaat aagtctggct
    33001 actgaaaatc acataataaa aaagcctcgg taacaaggct ttgagtttta tgattgtttc
    33061 ttaggtacgg aatacacttc aatgtgttgt cccagtatct taatgtcgac tggtagattg
    33121 tctgatttat cgccatcaac atcggactct aattcgatat cagaagaagt tttaatatta
    33181 cgtgccttta tatattcaat attcttgata gaatgattga actatagtaa attgaaacta
    33241 taatagtaca ccgtggatgc taaaatattt ctagaaatta atttgatttc cctaatcaag
    33301 ctgttcgtat cttatttcaa tcta
//
LOCUS       DAVBEO010000020        33056 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 009
            SAMEA1678075-rid20185393.denovo.020, whole genome shotgun sequence.
ACCESSION   DAVBEO010000020 DAVBEO010000000
VERSION     DAVBEO010000020.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678075
            Sequence Read Archive: ERR226392
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 33056)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33056)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980207.1
            Genome Coverage       :: 150x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:50:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 72 of 147
            Pseudo Genes (incomplete)         :: 72 of 147
            Pseudo Genes (internal stop)      :: 42 of 147
            Pseudo Genes (multiple problems)  :: 32 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33056
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678075-rid20185393.denovo.020"
                     /strain="KS 009"
                     /db_xref="taxon:1313"
     gene            complement(554..1243)
                     /gene="rplA"
                     /locus_tag="VQ543_000960"
     CDS             complement(554..1243)
                     /gene="rplA"
                     /locus_tag="VQ543_000960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L1"
                     /protein_id="HET2611699.1"
                     /translation="MAKKSKQLRAALEKIDSTKAYSVEEAVALAKETNFAKFDATVEV
                     AYNLNIDVKKADQQIRGAMVLPNGTGKTSRVLVFARGAKAEEAKAAGADFVGEDDLVA
                     KINDGWLDFDVVIATPDMMGLVGRLGRVLGPRNLMPNPKTGTVTMDVAKAVEESKGGK
                     ITYRADRAGNVQAIIGKVSFEAEKLVENFKAFNETIQKAKPATAKGTYVTNLTITTTQ
                     GVGIKVDVNSL"
     gene            complement(1450..1875)
                     /gene="rplK"
                     /locus_tag="VQ543_000961"
     CDS             complement(1450..1875)
                     /gene="rplK"
                     /locus_tag="VQ543_000961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004226069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11"
                     /protein_id="HET2611700.1"
                     /translation="MAKKVEKLVKLQIPAGKATPAPPVGPALGQAGINIMGFTKEFNA
                     RTADQAGMIIPVVISVYEDKSFTFVTKTPPAAVLLKKAAGVEKGSGTPNKTKVATVTR
                     AQVQEIAETKMPDLNAANVESAVRMIEGTARSMGFTVID"
     gene            complement(1998..2714)
                     /locus_tag="VQ543_000962"
     CDS             complement(1998..2714)
                     /locus_tag="VQ543_000962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M15 family metallopeptidase"
                     /protein_id="HET2611701.1"
                     /translation="MKKRYLVLTALLALSLAACSQEKAKNEDGAAKTEQTAKADGTVG
                     SKSQGAAQKKAEVVNKGDYYSIQGKYDEIIVANKHYPLSKDYNPGENPTAKAELVKLI
                     KAMQEAGFPISDHYSGFRSYETQTKLYQDYVNQDGKEAADRYSARPGYSEHQTGLAFD
                     VIGTNGDLVTEEKAAQWLLDHAADYGFVVRYLKGKEKETGYMAEEWHLRYVGKEAKEI
                     AASGLSLEEYFGFEGGDYVD"
     gene            complement(2717..3187)
                     /locus_tag="VQ543_000963"
     CDS             complement(2717..3187)
                     /locus_tag="VQ543_000963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HET2611702.1"
                     /translation="MCLICQRIELIKKGENPYFVKELETGYLVIGDHQYFAGYSLFLA
                     KEHVSELHHLEKKTRIRFLEEMSVVQEAVAKAFAAEKMNIELLGNGDAHLHWHLFPRR
                     RGDMNGYGLNGRGPVWWIPFEEMTAEICQSKPDEIKRLVERLSSEVDKLLEIKE"
     gene            complement(3189..4226)
                     /locus_tag="VQ543_000964"
     CDS             complement(3189..4226)
                     /locus_tag="VQ543_000964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001077203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M42 family metallopeptidase"
                     /protein_id="HET2611703.1"
                     /translation="MNQTVEYIKELTAIASPTGFTREISNYLVKTLEGFGYQPVRTAK
                     GGVNVTIKGQNDEQHRYVTAHVDTLGAIVRAVKPDGRLKLDRIGGFPWNMIEGENCTV
                     HVASTGQKVLGTILIHQTSCHVYKDAGTAERTQDNMEVRLDVKVSNEKETRALGIEVG
                     DFISFDPRTVVTDTGFIKSRHLDDKVSAAMLLNLLRIYKKEKIELPVTTHFAFSVFEE
                     VGHGANSNIPAQVVEYLAVDMGAMGDDQQTNEYTVSICVKDASGPYHYDFRQHLVALA
                     KEQDIPFKLDIYPFYGSDASAAMSAGAEVKHALLGAGIESSHSYERTHIDSVVATERM
                     VDAYLKSALVD"
     gene            complement(4324..5649)
                     /gene="brnQ"
                     /locus_tag="VQ543_000965"
     CDS             complement(4324..5649)
                     /gene="brnQ"
                     /locus_tag="VQ543_000965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006152071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HET2611704.1"
                     /translation="MAKKGTLTGLLLFGIFFGAGNLIFPPSLGALSGEHFLPAIAGFV
                     FSGVGIAVLTLIIGTLNPKGYIYEISTKIAPWFATLYLSVLYLSIGPFFATPRTATTA
                     YEVGISPLLSDANKGLGLIVFTVLYFAAAYLISLNPSKILDRIGRILTPVFAILIVIL
                     VVLGAIKYGGTSPQAASAAYQASAFGTGFLEGYNTLDALASVAFSVIAVQTLKQLGFS
                     SKKEYISTIWVVGIVVALAFSALYIGLGFLGNHFPVPAEAMKGGTPGVYILSQATQEI
                     FGSTAQLFLAAMVTVTCFTTTVGLIVSTAEFFNERFPQISYKVYATAFTLIGFAIANL
                     GLDAIIKYSIPVLVILYPITIAIVMIVIVNKFVALSKPGMQLTIAVVTVIAIASVLGS
                     SFKVEFLANLVSVLPFAKASLPWLVPAIVGILLSLVLPNKQESDVFEME"
     gene            complement(5820..5912)
                     /locus_tag="VQ543_000966"
     CDS             complement(5820..5912)
                     /locus_tag="VQ543_000966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HET2611705.1"
                     /translation="MRSARACQFLLEQGYNVINVQGGMLAFEEL"
     gene            complement(5955..6107)
                     /locus_tag="VQ543_000967"
     CDS             complement(5955..6107)
                     /locus_tag="VQ543_000967"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HET2611706.1"
                     /translation="MKEIAFDAFYQLYQNDQLSLVDVREVDEFAALHLEGAHNLPLSQ
                     LADSYD"
     gene            complement(6267..6845)
                     /locus_tag="VQ543_000968"
     CDS             complement(6267..6845)
                     /locus_tag="VQ543_000968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase family protein"
                     /protein_id="HET2611707.1"
                     /translation="MSQIERIKQAIMADSQNASYTERGIEPLFAAPKTARINIIGQAP
                     GLKTQEAGLYWKDKSGDRLRDWLGVDEDTFYNSGYFAVLPMDFYFPGHGKSGDLPPCT
                     GFAEKWHPQLLQELPDIQLTLLIGQYAQAYYLQEKISGKVTERVKHYKDYLPAYFPLV
                     HPSPRNQIWMAKNPWFEAEVVPDLKKRIKTIL"
     gene            complement(6899..8299)
                     /gene="pepV"
                     /locus_tag="VQ543_000969"
     CDS             complement(6899..8299)
                     /gene="pepV"
                     /locus_tag="VQ543_000969"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000125034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase PepV"
                     /protein_id="HET2611708.1"
                     /translation="MIAIDFTAEVEKRKEDLLADLFSLLEINSERDDSKADAQHPFGP
                     GPVKALEKFLEIADRDGYPTKNVDNYAGHFEFGDGEEVLGIFAHMDVVPAGSGWDTDP
                     YTPTIKDGRLYARGASDDKGPTTACYYGLKIIKELGLPTSKKVRFIVGTDEESGWADM
                     DYYFEHVGLAKPDFGFSPDAEFPIINGEKGNITEYLHFAGENTGAARLHSFTGGLREN
                     MVPESATAVVSGDLTDLQAKLDAFVAEHKLRGELQEEAGQYKVTIIGKSAHGAMPASG
                     VNGATYLALFLSQFGFAGPAKDYLDIAGKILLNDHEGENLKIAHVDEKMGALSMNAGV
                     FRFDETSADNTIALNIRYPKGTSPEQIKSILENLPVASVSLSEHGHTPHYVPMEDPLV
                     QTLLNVYEKQTGLKGHEQVIGGGTFGRLLERGVAYGAMFPDSIDTMHQANEFIALDDL
                     FRAAAIYAEAIYELIK"
     gene            complement(8312..8917)
                     /locus_tag="VQ543_000970"
     CDS             complement(8312..8917)
                     /locus_tag="VQ543_000970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002924506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HET2611709.1"
                     /translation="MKFLELNKKRHATKHFTDKPVDLKDVRTAIEIATLAPSAHNSQP
                     WKFVVVREKNAELAKLAYGSNFEQVSSAPVTIALFTDTDLAKRARKIARVGGANNFSE
                     EQLQYFMKNLPAEFARYNEQQVSDYLALNAGLVAMNLVLALTDQGIGSNIILGFDKSK
                     VNEVLEIEDRFRPELLITVGYTDDKLEPSYRLPVDEIIEKR"
     gene            9088..9888
                     /locus_tag="VQ543_000971"
     CDS             9088..9888
                     /locus_tag="VQ543_000971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HET2611710.1"
                     /translation="MKKFSLLLAILPFLVACGNQATPKETSAQKTIVLATAGDVPPFD
                     YEDKGNLTGFDIEVLKAVDEKLSDYEIQFQRTAWESIFPGLDSGHYQAAANNLSYTKE
                     RAEKYLYSLPISNNPLVLVSNKKNPLTSLDQIAGKTTQEDTGTSNAQFINNWNQKHTD
                     NPATINFSGEDIGKRILDLANGEFDFLVFDKVSVQKIIKDRGLDLSVVDLPSADSPSN
                     YIIFSSDQKEFKEQFDKALKELYQDGTLEKLSNTYLGGSYLPDQSQLQ"
     gene            complement(10070..10903)
                     /locus_tag="VQ543_000972"
     CDS             complement(10070..10903)
                     /locus_tag="VQ543_000972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001015777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase family protein"
                     /protein_id="HET2611711.1"
                     /translation="MNHKIAILSDIHGNATALEAVIADAKTQGASEYWLMGDIFLPGS
                     GANDLVALLKELPITASVRGNWNDCVLEALDGQYGLEDPQEIQLMRMTQFLMERMDPA
                     TTVWLRSLPLLEKKEIAGLRFSISHNLPNKNYGGDLLVENDTEKFDQLLDAETDVAVY
                     GHVHKQLLRYGSQGQQIINPGSIGMPYFNWEALKNHRAQYAVIEVEDGELVNIQFRKV
                     AYDYEAELELAKSKGLPFIEMYEELRRDDNYQGHNLELLASLIEKHGYVEDVKNFFDF
                     L"
     gene            complement(10893..12740)
                     /gene="uvrC"
                     /locus_tag="VQ543_000973"
     CDS             complement(10893..12740)
                     /gene="uvrC"
                     /locus_tag="VQ543_000973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001061148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrC"
                     /protein_id="HET2611712.1"
                     /translation="MNNLIKSKLELLPTSPGCYIHKDKNGTIIYVGKAKNLRNRVRSY
                     FRGIHDTKTEALVSEIVDFEFIVTESNIEALLLEINLIKENKPKYNIMLKDDKSYPFI
                     KITNERYPRLIITRQVKKDGGLYFGPYPDVGAANEIKRLLDRIFPFRKCTNPPSKVCF
                     YYHIGQCMAHTICKKDEAYFKSMAQEVSDFLKGQDDKIIDDLKSKMAVAAQSMEFERA
                     AEYRDLIQAIGTLRTKQRVMAKDLQNRDVFGYYVDKGWMCVQVFFVRQGKLIERDVNL
                     FPYFNDPDEDFLTYVGQFYQEKSHLVPNEVLIPQDIDEEAVKALVDTKILKPQRGEKK
                     QLVNLAIKNARVSLEQKFNLLEKSVEKTQGAIENLGRLLQIPTPVRIESFDNSNIMGT
                     SPVSAMVVFVNGRPSKKDYRKYKIKTVVGPDDYASMREVIRRRYGRVQREALTPPDLI
                     VIDGGQGQVNIAKQVIQEELGLDIPIAGLQKNDKHQTHELLFGDPLEVVDLSRNSQEF
                     FLLQRIQDEVHRFAITFHRQLRSKNSFSSQLDGIDGLGPKRKQNLMRHFKSLTKIKEA
                     SVDEIVEVGVPRAVAEAVQRKLNPQETEILLQVAEERVDYQTEGNHNKP"
     gene            complement(12780..13481)
                     /locus_tag="VQ543_000974"
     CDS             complement(12780..13481)
                     /locus_tag="VQ543_000974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001267193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="matrixin family metalloprotease"
                     /protein_id="HET2611713.1"
                     /translation="MRWLFRLIGAFFSFVWRLFWRLVWIVVLLCVLAFGLLWYLNGDF
                     QGALKQAERSVKMGQQSIDQWEKTGQLPKLSQTDSHQHSEGRWAQASARIYLDPQMDS
                     RFQEAYLEAIQNWNQTGAFNFELVTESSKADITATEMNDGGTPVAGEAESQTNLLTGQ
                     FLSVTVRLNHYYLSNPYYGYSYERLVHTAEHELGHAIGLDHTDEKSVMQPAGSFYGIQ
                     EEDVANLRKIYETSE"
     gene            complement(13560..14792)
                     /gene="murN"
                     /locus_tag="VQ543_000975"
     CDS             complement(13560..14792)
                     /gene="murN"
                     /locus_tag="VQ543_000975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001229509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan bridge formation alanyltransferase
                     MurN"
                     /protein_id="HET2611714.1"
                     /translation="MALTTLTKEEFQTYSDQVSSRSFMQSVQMGDLLEKRGARIVYLA
                     LKQEGEIQVAALVYSLPMLGGLHMELNSGPIYTQQDALPVFYAELKEYAKQNGVLELL
                     VKPYETYQTFDSQGNPIDAEKKSIIQGLTDLGYQFDGLTTGYPGGEPDWLYYKDLTEL
                     TEKSLLKSFSKKGKPLVKKAETFGIRLKKLKREELSIFKNITKETSERREYSDKSLEY
                     YEHFYDTFGEQAEFLIASLNFSEYMSKLQGEQSKLEENLDKLRLDLSKNPHSEKKQNQ
                     LREYSSQFETFEVRKAEARDLIEKYGEEDIVLAGSLFVYMPQETTYLFSGSYTEFNKF
                     YAPALLQKYVMLESIKRGIPKYNFLGIQGIFDGSDGVLRFKQNFNGYIVRKAGTFRYH
                     PSPLKYKAIQLLKKIVGR"
     gene            complement(14797..16017)
                     /gene="murM"
                     /locus_tag="VQ543_000976"
     CDS             complement(14797..16017)
                     /gene="murM"
                     /locus_tag="VQ543_000976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001819885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan bridge formation alanyltransferase
                     MurM"
                     /protein_id="HET2611715.1"
                     /translation="MYRYQIGIPTLEYDQFVKEHELANVLQSSAWEEVKSNWQHEKFG
                     VYREEKLLATASILIRTLPLGYKMFYIPRGPILDYGDKELLNFAIQSIKSYARSKRAV
                     FVTFDPSICLSQSLINQEKTEFPENLAIIDSLQQMGVRWSGKTEEMGDTIQPRIQAKI
                     YKENFEEDKLSKSTKQAIRTARNKGLEIQYGGLELLDSFSELMKKTEKRKEIHLRNEA
                     YYKKLLDNFKDKAYITLATLDVSKRSQELEEQLAKNRALEETFTESTRTSKVEAQKKE
                     KERLLEELTFLQEYIDVGQARVPLAATLSLEFGTTSVNIYAGMDDDFKRYNAPILTWY
                     ETARYAFERGMVWQNLGGVENSLNGGLYHFKEKFNPTIEEYLGEFTMPTHPLYPLLRL
                     ALDFRKTLRKKHRK"
     gene            complement(16129..16908)
                     /locus_tag="VQ543_000977"
     CDS             complement(16129..16908)
                     /locus_tag="VQ543_000977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
                     /protein_id="HET2611716.1"
                     /translation="MAVMKIEYYSQVLDMEWGVNVLYPDANRVEEPECEDIPVLYLLH
                     GMSGNHNSWLKRTNVERLLRGTNLIVVMPNTSNGWYTDTQYGFDYYTALAEELPQVLK
                     RFFPNMTSKREKTFIAGLSMGGYGCFKLALATNRFSHAASFSGALSFQNFSPESQNLG
                     SPAYWRGVFGEIRDWTTSPYSLESLAKKSDKKTKLWAWCGEQDFLYEANNLAVKNLKK
                     LGFDVTYSHSAGTHEWYYWEKQLEVFLTTLPIDFKLEERLT"
     gene            complement(16977..18638)
                     /locus_tag="VQ543_000978"
     CDS             complement(16977..18638)
                     /locus_tag="VQ543_000978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HET2611717.1"
                     /translation="MSNISLTTLGGVRENGKNMYIAEIGESIFVLNVGLKYPENEQLG
                     VDVVIPNMDYLFENSDRIAGVFLTHGHADAIGALPYLLAEAKVPVFGSELTIELAKLF
                     VKGNDAVKKFNDFHVIDENTEIDFGGTVVSFFPTTYSVPESLGIVLKTSEGSIVYTGD
                     FKFDQTASESYATDFARLAEIGRDGVLALLSDSANADSNIQVASESEVRDEITQTIAD
                     WEGRIIVAAVSSNLSRIQQIFDAADKTGRRIVLTGFDIENIVRTAIRLKKLSLANEIL
                     LIKPKDMSRFEDHELIILETGRMGEPINGLRKMSIGRHRYVEIKDGDLVYIATAPSIA
                     KEAFVARVENMIYQAGGVVKLITQSLHVSGHGNVRDLQLMINLLQPKYLFPVQGEYRE
                     LDAHAKAAMAVGMLPEHIFIPKKGTTMAYENGDFVPAGSVSAGDILIDGNAIGDVGNV
                     VLRDRKILSEDGIFIVAITVNRREKKIVARARVHTRGFVYLKKSRDILRESSELINQT
                     VEDYLQGDDFDWADLKGKVRDNLTKYLFDQTKRRPAILPVVMEAK"
     gene            complement(18813..21035)
                     /gene="recJ"
                     /locus_tag="VQ543_000979"
     CDS             complement(18813..21035)
                     /gene="recJ"
                     /locus_tag="VQ543_000979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001832038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded-DNA-specific exonuclease RecJ"
                     /protein_id="HET2611718.1"
                     /translation="MITPTYEWQFALQVEDADFTKIAKKAGLGPEVARLLFERGIQDQ
                     ESLKKFLEPSLEDLHDAYLLHDMDKAVERIRQAIEEGENILVYGDYDADGMTSASIVK
                     ESLEQLGAECRVYLPNRFTDGYGPNASVYKYFIEQEGISLIVTVDNGVAGHEAIALAQ
                     SMGVDVIVTDHHSMPETLPDAYAIVHPEHPDADYPFKYLAGCGVAFKLACALLEEVQV
                     ELLDLVAIGTIADMVSLTDENRILVQYGLEMLGHTQRIGLQEMLDMAGIAANEVTEET
                     VGFQIAPRLNALGRLDDPNPAIDLLTGFDDEEAHEIALMIHQKNEERKEIVQSIYEEA
                     KTMVDPEKKVQVLAKEGWNPGVLGIVAGRLLEELGQTVIVLNIEDGRAKGSARSVEAV
                     DIFEALDPHRDLFIAFGGHAGAAGMTLEVEQLSDLSQVLEDYVREKGADAGGKNKLNL
                     DEELDLEALSLETVKSFERLAPFGMDNQKPIFYIKNFQVESARTMGAGNAHLKLKISK
                     GEASFEVVAFGQGRWATEFSQTKNLELAVKLSVNQWNGQTALQLMMVDARVEGVQLFN
                     IRGKNAVLPEGVPVLDFPGELPNLAASEAVVVKNIPEDITQLKTIFQEQHFSAVYFKN
                     DIDKTYYLTGYGTRDQFAKLYKTIYQFPEFDIRYKLKDLAAYLNIQQILLVKMIQVFE
                     ELGFVTIKDGVMTVNKEAPKREIGESQIYQNLKQTVKDQEMMALGTVQEIYDFLMEKE
                     "
     gene            21312..22070
                     /locus_tag="VQ543_000980"
                     /pseudo
     CDS             21312..22070
                     /locus_tag="VQ543_000980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398007.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
     gene            22110..22874
                     /locus_tag="VQ543_000981"
     CDS             22110..22874
                     /locus_tag="VQ543_000981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000624332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HET2611719.1"
                     /translation="MISLFGLAAAKPVQADTSIADIQKRGELVVGVKQDVPNFGYKDP
                     KTGTYSGIETDLAKMVADELKVKIRYVPVTAQTRGPLLDNEQVDMDIATFTITDERKK
                     LYNFTSPYYTDASGFLVNKSAKIKKIEDLNGKTIGVAQGSITQRLITELGKKKGLKFK
                     FVELGSYPELITSLHAHRIDAFSVDRSILSGYTSKRTELLDDSFKPSDYGIVTKKSNT
                     ELNDYLDNLVTKWSKDGSLQKLYDRYKLKPSSHTAD"
     gene            22887..23564
                     /locus_tag="VQ543_000982"
     CDS             22887..23564
                     /locus_tag="VQ543_000982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HET2611720.1"
                     /translation="MIDLSSWTAYFQDFGQFFNGFLFTLALAIGSFILAMVLGIFFGA
                     MSTSKRPILRILAHIFVEFYQNTPLLVQFVIVFYGLPLISDHTIMIPIYWTAVLCMGL
                     YHGAYIAEVIRSGIQSIPSGQMEAALSQGFTYISAMRLIILPQTFRIILPPLTNQIVN
                     LIKNTSTVAIISGVDLMFVTKSWSALNGNYIPAFLGAALLYFALCFPVAQFGRKMEQA
                     NKKAYSL"
     gene            23574..24233
                     /locus_tag="VQ543_000983"
     CDS             23574..24233
                     /locus_tag="VQ543_000983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000443867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HET2611721.1"
                     /translation="MESILEVLTPDNLVFIFKGFGLTLYISLIAIILSTIIGTVLAVM
                     RNGKNPVLRIISSIYIEFVRNVPNLLWIFTIFLVFKMKSTPAGITAFTLFTSAALAEI
                     IRGGLNTVDKGQYEAGMSQGFTSAQILYYIILPQAIRKMLPAIISQFVTVIKDTSLLY
                     SVIALQELFGASQILMGRYFEPEQVFSLCILIALIYFSFNLAISSLSHMLAKRWQQAA
                     E"
     gene            24528..25718
                     /locus_tag="VQ543_000984"
     CDS             24528..25718
                     /locus_tag="VQ543_000984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferric reductase-like transmembrane
                     domain-containing protein"
                     /protein_id="HET2611722.1"
                     /translation="MKSVKGLLFIIASFILTLLTWMNTSPQFMIPGLALTSLSLTFIL
                     ATRLPLLESWFHGLEKVYTVHKFTAFLSIILLIFHNFSMGGLWGSRLAAQFGNLAIYI
                     FASIILVAYLGKYIQYEAWRWIHRLVYLAYILGLFHIYMIMGNRLLTFNLLSFLVGSY
                     ALLGLLAGFYIIFLYQKISFPYLGKITHLKRLNHDTREIQIHLSRPFNYQSGQFAFLK
                     IFQEGFESAPHPFSISGGHGQTLYFTVKNSGDHTNNIYDNLQAGSKVTLDRAYGHMII
                     EEGRENQVWIAGGIGITPFISYIREHPILDKQVHFYYSFRGDENAVYLDLLRNYAQKN
                     PNFELHLIDSTKDGYLNFEQKEVPEHATVYMCGPISMMKALAKQIKKQNPKTELIYEG
                     FKFK"
     gene            complement(26039..26920)
                     /locus_tag="VQ543_000985"
     CDS             complement(26039..26920)
                     /locus_tag="VQ543_000985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-bisphosphate aldolase"
                     /protein_id="HET2611723.1"
                     /translation="MAIVSAEKFVQAARDNGYAVGGFNTNNLEWTQAILRAAEAKKAP
                     VLIQTSMGAAKYMGGYKVARNLIANLVESMGITVPVAIHLDHGHYEDALECIEVGYTS
                     IMFDGSHLPVEENLKLAKEVVEKAHAKGISVEAEVGTIGGEEDGIIGKGELAPIEDAK
                     AMVETGIDFLAAGIGNIHGPYPVNWEGLDLDHLQKLTEALPGFPIVLHGGSGIPDEQI
                     QAAIKLGVAKVNVNTECQIAFANATRKFARDYEANEAEYDKKKLFDPRKFLADGVKAI
                     QASVEERIDVFGSEGKA"
     gene            complement(27061..28389)
                     /gene="vncS"
                     /locus_tag="VQ543_000986"
     CDS             complement(27061..28389)
                     /gene="vncS"
                     /locus_tag="VQ543_000986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase VncS"
                     /protein_id="HET2611724.1"
                     /translation="MKRTGLFAKIFIYTFSIFSVLVICLHLAIYFLFPSTYLSHRQET
                     IGQKATAIAQSLEGKDRQSIEQVLDLYSQTSDIKGTVKGEMTEDKLEVKDSLPLDTDR
                     QTTSLFIEEREVKTQDGATMILQFLASMDLQKEAEQISLQFLPYTLLASFLISLLVAY
                     IYARTIVAPILEIKRVTRRMMDLDSQVRLRVDSKDEIGNLKEQINSLYQHLLTVIADL
                     HEKNEAILQLEKMKVEFLRGASHELKTPLASLKILIENMRENIGRYKDRDQYLGVALG
                     IVDELNHHVLQILSLSSVQELRDDRETIDLLQMTQNLVKDYALLAKERELQIDNSLTH
                     QQAYLNPSVMKLILSNLISNAIKHSVPGGLVRIGEREGELFIENSCSSEEQEKLAQSF
                     SDNASRKVKGSGMGLFVVKSLLEHEKLAYRFEMEENRLTFFIDFPKVVQD"
     gene            complement(28386..29042)
                     /gene="vncR"
                     /locus_tag="VQ543_000987"
     CDS             complement(28386..29042)
                     /gene="vncR"
                     /locus_tag="VQ543_000987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor VncR"
                     /protein_id="HET2611725.1"
                     /translation="MKILIVEDEEMIREGVSDYLTDCGYETIEAADGQEALEQFSSYE
                     VALVLLDIQMPKLNGLEVLAEIRKTSQVPVLMLTAFQDEEYKMSAFASLADGYLEKPF
                     SLSLLKVRVDAIFKRYYDTGRIFSYKDTKVDFESYSASIAGQEVPINAKELEILDYLV
                     KNEGRALTRSQIIDAVWKATDEVPFDRVIDVYIKELRKKLDLDCILTVRNVGYKLERK
                     "
     gene            complement(29091..29174)
                     /gene="pep27"
                     /locus_tag="VQ543_000988"
     CDS             complement(29091..29174)
                     /gene="pep27"
                     /locus_tag="VQ543_000988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_198524447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative autolysis signal peptide Pep27"
                     /protein_id="HET2611726.1"
                     /translation="MRKEFHNVLSSGQLLADKRPARDYNRK"
     gene            complement(29354..30733)
                     /gene="vex3"
                     /locus_tag="VQ543_000989"
     CDS             complement(29354..30733)
                     /gene="vex3"
                     /locus_tag="VQ543_000989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit Vex3"
                     /protein_id="HET2611727.1"
                     /translation="MLHNAFAYVTRKFFKSIVIFLIILLMASLSLVGLSIKGATAKAS
                     QETFKNITNSFSMQINRRVNQGTPRGAGNIKGEDIKKITENKAIESYVKRINAIGDLT
                     GYDLIETPETKKNLTADRAKRFGSSLMITGVNDSSKEDKFVSGSYKLVEGEHLTNDDK
                     DKILLHKDLAAKHGWKVGDKVKLDSNIYDADNEKGAKETVEVTIKGLFDGHNKSAVTY
                     SQELYENTAITDIHTAAKLYGYTEDTAIYGDATFFVTADKNLDDVMKELNGISGINWK
                     SYTLVKSSSNYPALEQSISGMYKMANLLFWGSLSFSVLLLALLLSLWINARRKEVGIL
                     LSIGLKQASILGQFITESILIAIPALVSAYFLANYTARAIGNTVLANVTSGVAKQASK
                     AAQASNLGGGAEVDGFSKTLSSLDISIQTSDFIIIFVLALVLVVLVMALASSNLLRKQ
                     PKELLLDGE"
     gene            complement(30785..31432)
                     /gene="vex2"
                     /locus_tag="VQ543_000990"
     CDS             complement(30785..31432)
                     /gene="vex2"
                     /locus_tag="VQ543_000990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000173730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding subunit Vex2"
                     /protein_id="HET2611728.1"
                     /translation="MTLLQLQDVTYRYKNTAEAVLYQIDYNFEPGKFYSIIGESGAGK
                     STLLSLLAGLDSPVEGSILFQGEDIRKKGYSYHRMHHISLVFQNYNLIDYLSPLENIR
                     LVNKKASKDTLLELGLDESQIKRNVLQLSGGQQQRVAIARSLVSEAPVILADEPTGNL
                     DPKTAGDIVELLKSLAQKTGKCVIVVTHSKEVAQASDITLELKDKKLTETRNTSK"
     gene            complement(31445..32722)
                     /locus_tag="VQ543_000991"
     CDS             complement(31445..32722)
                     /locus_tag="VQ543_000991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001068247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET2611729.1"
                     /translation="MNPIQRSWAYVSRKRLRSFILFLILLVLLAGISACLTLMKSNKT
                     VESNLYKSLNTSFSIKKIENGQTFKLSDLASVSKIKGLENVSPELETVAKLKDKEAVT
                     GEQSVERDDLSAADNNLVSLTALEDSSKDVTFTSSAFNLKEGRHLQKGDSKKILIHEE
                     LAKKNGLSLHDKIGLDAGQSESGKGQTVEFEIIGIFSGKKQEKFTGLSSDFSENQVFT
                     DYESSQTLLGNSEAQVSAARFYVENPKEMDGLMKQVENLALENQGYQVEKENKAFEQI
                     KDSVATFQTFLTIFLYGMLIAGAGALILVLSLWLRERVYEVGILLALGKGKSSIFLQF
                     CLEVVLVSLGALLPAFVAGNGITSYLLQTLLASGDQASLQDTLAKASSLSTSILSFAE
                     SYVFLVLLSCLSVALCFLFLFRKSPKEILSSIS"
BASE COUNT         9331 a         7576 c         6146 g        10003 t
ORIGIN      
        1 ttcgaaatcg agtaggggat aatctctagc ccctctcaca ccaccgtacg tgccgttcga
       61 catacggcgg ttcaactaac tgttaacgca tgtcgttcaa ggtaataatc caaacacgaa
      121 accagtccac gtttttcaag gactggtttt gatatagcac gtttaagtac cgacttctga
      181 gctactatag tagattgaaa ctagaatagt acatctcttc ttctaaaaca ttgttagaaa
      241 tcgatttggc tgccctgatc gattcgtcct actcttattt cattttacta taattgatag
      301 tggtcgcccc agccagatac cttatccgct atataggcct tattatcatg ttcctgttcg
      361 tagagccacg atttcgctat cccttcctct gacgattctt atttcctgcg tcagacttgg
      421 gaatcgctat tgggttcacc ggtagcaggt gcccaccgag gacttacacc tcagatatac
      481 gacatgcccg tcgtacatca aaaaaagttg agacatagcg tcttcaactt ttttacatta
      541 ctttaactac tgattaaagt gagtttacgt caactttgat accaacacct tgagtagttg
      601 tgatagtcaa gtttgttacg taagttcctt tagctgtagc tggttttgct ttttggattg
      661 tttcgttgaa agctttaaag ttttcaacca atttttcagc ttcaaatgat actttaccga
      721 tgattgcttg aacgttacct gcacggtcag cacggtaagt gattttacca cctttagact
      781 cttcaactgc tttagcaaca tccattgtta cagtaccagt tttagggttt ggcatcaagt
      841 tacgtggtcc aaggacacgt ccaagacgtc caacaagacc catcatatca ggtgtagcga
      901 taactacgtc gaagtccaac caaccgtcgt tgattttagc aacaaggtca tcttcaccaa
      961 caaagtctgc accagcagct tttgcttctt cagcttttgc accacgtgcg aaaacaagaa
     1021 cgcgtgaagt tttaccagta ccgtttggca ataccattgc tccacggatt tgttgatcag
     1081 cttttttaac gtcgatgttc aagttgtaag caacttctac agttgcgtca aattttgcaa
     1141 agtttgtttc ttttgcaagt gctacagctt cttctacgct gtatgctttt gtgctgtcga
     1201 ttttctcaag agcagcacga agttgtttgc tttttttagc cattttctat tctccttgta
     1261 agtggttcaa tcgattttca tctcccacgt cacttctcga aatgatgaag tcttgcgggt
     1321 tttcagtcta ttagattctt ttcctacggc cttaagctcc cttgctgtac ccaagtacaa
     1381 gcatcagtca cttgcctagt atgaaaagca actaatagac tgctgtgaga ttttctactg
     1441 tgttattgat tagtcaataa cagtgaatcc catagaacga gcagtacctt cgatcatacg
     1501 cactgcagac tctacgtttg ctgcgttcaa atctggcatc ttagtttctg caatttcttg
     1561 tacttgtgca cgagtaactg tagcaacttt agttttatta ggtgtacctg atcctttttc
     1621 aacacctgca gcttttttca aaagaacagc agctggtggt gttttcgtaa cgaaagtaaa
     1681 tgatttatct tcgtaaactg agataacaac tggaatgatc ataccagctt ggtcagctgt
     1741 acgagcgttg aactcttttg tgaatcccat gatgttgata ccagcttgac caagagcagg
     1801 tccaaccggt ggagctggtg tagctttacc agcagggatt tgcaatttta caagtttttc
     1861 gactttttta gccattttta aatcctcctt tgtggttttg gcggtaatta gagattttta
     1921 cctcccacaa gtatgttttt cacataccca tctattatac actatttatc tggaattgca
     1981 agagaaaagt ttatttttta atcgacgtaa tctccacctt caaagccgaa atactcttcc
     2041 aaactgaggc cactagctgc aatctcttta gcctcttttc cgacataacg aaggtgccat
     2101 tcctcagcca tatagcctgt ttccttttcc ttacctttga gataacgtac aacaaagcca
     2161 taatcagccg catgatccaa gagccattgg gccgcttttt cttctgtcac caaatcacca
     2221 tttgtcccaa tcacatcaaa ggctaaacct gtctggtgct cgctatagcc aggacgggca
     2281 gaataacggt cggcagcttc tttcccatct tgattgacat aatcttgata gagcttggtc
     2341 tgagtttcat aacttctaaa gccactgtaa tgatcgctaa tggggaaacc tgcctcttgc
     2401 atagctttga tgagcttgac caactcagcc ttggctgttg gattttcccc tggattgtag
     2461 tcttttgaca atggatagtg tttgttggct acgatgattt catcgtattt cccttgaatg
     2521 ctgtaatagt ctcctttgtt aaccacttct gcttttttct gggcagctcc ttgagactta
     2581 cttcctactg ttccatcagc tttagcagtt tgctctgtct tagctgctcc atcttcattt
     2641 tttgcttttt cttgtgaaca agctgctaga ctcaaggcta gcaaggctgt caagacaagg
     2701 tatctttttt tcatctttac tcctttattt ctaatagttt atctacttct gatgataaac
     2761 gttcgactaa tcttttaatc tcatcaggtt ttgattggca gatttctgct gtcatttctt
     2821 caaagggaat ccaccatact ggaccacgtc cattgaggcc ataaccattc atatcacctc
     2881 ttcgtctagg aaacagatgc caatggagat gagcatcgcc atttcctagt agttcgatat
     2941 tcattttctc agcagcaaag gccttggcaa ctgcctcttg gaccacactc atttcttcta
     3001 gaaaacgtat tctagttttc ttttctaaat gatgcaattc gctgacatgt tccttggcta
     3061 gaaagagact atagcctgca aaatactggt ggtctccaat cacaagatag cctgtttcca
     3121 actctttgac aaaataggga ttttctccct tcttgatgag ctcaattctc tggcaaatca
     3181 aacacatatt agtctaccaa tgcactctta agataggcat cgaccattcg ttctgttgcg
     3241 accaccgagt caatatgagt gcgctcataa gaatgactag actcgatacc cgcaccaaga
     3301 agggcatgct tgacctctgc ccctgcagac atagccgctg aagcatccga accataaaat
     3361 ggatagatgt ccagcttaaa aggaatatct tgctctttag ccaaggcaac caagtgttga
     3421 cggaagtcat agtgataagg acctgaggca tccttgacac agatagatac tgtgtactca
     3481 tttgtctgct ggtcatctcc catagctccc atatccacag ccagatattc tactacctga
     3541 gcaggaatgt tagaattagc accatgtcct acttcttcaa aaactgaaaa agcaaaatga
     3601 gttgttactg gcaattcaat cttctctttc ttataaatac gaagcaggtt gagcaacatc
     3661 gctgcgctga ccttatcatc caaatgacga gacttgataa aacctgtatc agtcacaaca
     3721 gttcgtggat cgaagctgat aaaatcaccg acctcaatcc caagagcacg agtttctttt
     3781 tcattgctta cttttacatc caaacgcact tccatattgt cctgcgtgcg ttctgcagtt
     3841 cctgcatcct tgtagacatg gcaagaagtt tggtggatga ggatggttcc taataccttt
     3901 tgacctgtgc tagccacatg aacggtacag ttttcacctt caatcatgtt ccaaggaaaa
     3961 ccaccgatac ggtccaattt aagacgacca tctggtttga cagcacgaac aatagcaccc
     4021 agtgtgtcca catgggcagt cacatagcga tgttgctcat cattttgacc tttgatggtc
     4081 acattgacac cacccttggc tgtgcgaact ggctggtaac caaaaccttc tagagtcttg
     4141 actaaataat tcgaaatttc acgagtgaag cccgttggcg atgcgatggc tgtcagttct
     4201 ttgatatatt ctactgtttg attcatttct tcacctcttt cgctacctat tataacacat
     4261 ttatcatcgg ataaaaaaag aaaatcactc ctgtagactt ggctacaaaa gtgatttaag
     4321 tgattattcc atttcaaaaa catcgctttc ttgcttgttt ggtagaacca atgagagcaa
     4381 gattccaaca atggctggca ccaaccatgg gagagatgcc ttggcaaaag gaagaacgct
     4441 aacaagattt gcaagaaact caaccttaaa cgagcttcct agtacgcttg caatggcaat
     4501 aactgtaacc acagcaattg tcaactgcat acctggtttt gaaagggcaa caaatttgtt
     4561 gacaatgaca atcataacga tagcaatcgt gattgggtac aagataacca gtactggaat
     4621 tgagtacttg ataatcgcat caagacccaa attggcaata gcaaatccaa tcaaggtaaa
     4681 ggctgtcgca taaaccttgt agctgatttg tgggaagcgc tcattaaaga actcagctgt
     4741 tgacacaatc aaaccaacag tcgttgtgaa gcaggttacg gtaaccatag ctgcaaggaa
     4801 gagttgagct gttgagccaa agatttcttg agtggcttgt gacaagatgt aaacacctgg
     4861 tgttccaccc ttcatcgctt cagctggtac tgggaaatga tttccaagaa aacctaaacc
     4921 gatgtaaaga gcgctgaagg caagggcaac aacgatacca acaacccaaa tagttgaaat
     4981 gtattctttc ttacttgaaa atccaagttg tttcaaggtt tgaactgcga ttacgctaaa
     5041 ggccactgag gcaagggcgt ccaaggtatt ataaccttct aggaaacctg taccaaaggc
     5101 agaagcttga taagcagctg aagcagcttg aggacttgtt ccaccatatt tgatagctcc
     5161 cagaacgacc aagataacaa tcaaaattgc aaagactggc gttaaaatac gtccaatgcg
     5221 gtctaagatt tttgatggat taagcgaaat caaataggct gccgcaaaat acagaaccgt
     5281 aaatacaatc aagccaagtc ctttatttgc atccgacaaa agggggctaa tccctacttc
     5341 gtaagctgtt gtagcagtac gtggggtagc aaagaatgga ccgattgaca agtaaagaac
     5401 tgagaggtaa agagtcgcaa accaaggcgc tatcttcgtt gaaatctcgt agatatatcc
     5461 tttaggattt agcgttccaa taataagggt caagacggcg ataccaacgc ctgaaaagac
     5521 aaaacctgcg atggcaggaa gaaaatgttc tccagataga gcacctagag aaggcggaaa
     5581 aatcaagttc cccgcaccaa aaaatattcc aaacaggagc aaacctgtta gggtaccttt
     5641 tttagccata aaaatctcct tcatatttat aaaatactga tctagtatac cacgattagg
     5701 agtctgaaaa aagcatcacg aggcaaatat taaatgtttt caattttctt aaaaataaga
     5761 attatctaaa aataaaactc tcctacccag tccacaccaa gtaggagaaa tgcaaaattt
     5821 taaagttctt caaaggctaa catgccaccc tggacattga taacattata accttgttct
     5881 aataggaatt ggcaagcacg cgccgatctc attccagatt tgcaaataat ataatgcaag
     5941 cgatctttgt ccaattaatc ataactatca gccaattgac taagcggtag gttgtgggca
     6001 ccttctaaat gaagagctgc aaactcatcc acttctctca catccactag agaaagctgg
     6061 tcgttttggt aaagctggta aaatgcgtca aaggctattt ctttcattct ttttcttcta
     6121 atactcttcg aaaatctctt caaaccacgt cagcgtcgcc ttaccgtgcg tatgttaccg
     6181 acttcgtcag ttttatctgc aacttcaaag ctgtactttg agcagcctac gactagcttc
     6241 ctagtttgct ctttgatttt cattgactat aaaatggttt taattctttt tttcaaatct
     6301 ggcactactt ctgcctcaaa ccaaggattt ttggccatcc agatttgatt tcgtggtgat
     6361 gggtgaacta gcggaaaata ggctggcaga tagtctttat agtgtttcac cctctccgtt
     6421 accttcccac tgattttctc ctgtaaatag taggcttggg catattgccc aatcaagagg
     6481 gttaactgaa tatcaggcaa ttcctgtaag agctgcggat gccatttttc tgcaaaacct
     6541 gtacaaggcg gaagatcacc cgacttgcca tgtcctggaa agtagaaatc cataggcaaa
     6601 acagcaaaat aacctgaatt gtaaaaggta tcttcatcca cacctagcca gtcccgcaaa
     6661 cggtcaccac ttttatcttt ccagtaaagg cctgcttctt gagttttaag tcccggagcc
     6721 tgaccgatga tattgatgcg agcagttttt ggcgctgcaa agagaggctc aatgccacgc
     6781 tctgtatagc tggcattctg cgaatccgcc atgatagcct gtttgattct ttcgatttga
     6841 gacatctact ttccctccaa aaagaagtcc aagcataaga tctcagactt ctatcgtttt
     6901 atttgatcaa ttcgtaaata gcttcggcat aaattgctgc tgctcggaag agatcgtcca
     6961 aggcaataaa ttcattggct tggtgcatgg tatcaattga gtctgggaac atagcaccat
     7021 aggcaactcc gcgctctaac aagcgaccaa aggttccacc accgatgact tgttcatgac
     7081 ctttaaggcc tgtttgtttt tcatagacat tcaacaaggt ttgcacaagt ggatcttcca
     7141 ttggcacata gtgaggggta tgaccatgtt ctgatagact gacagaagca actggcaagt
     7201 tttctaggat tgacttgatt tgttctggac ttgttccttt tggatagcgg atgttaaggg
     7261 caatggtatt atcagcactt gtttcatcga agcggaagac gccggcattc atagaaagag
     7321 cacccatctt ttcatccaca tgagcaatct tgagattttc accctcatga tcgttcaaga
     7381 gaattttacc tgcgatgtca aggtagtctt tggctggacc agcaaagcca aactggctga
     7441 ggaagagggc aaggtaagtt gcgccattga cacctgaagc aggcatagca ccgtgggctg
     7501 atttaccaat gatcgtcacc ttgtattggc cagcttcttc ttggagttct cctctaagtt
     7561 tgtgttctgc aacaaaggca tctagtttag cttgcaagtc tgtcaagtca cctgaaacga
     7621 ctgctgttgc tgattctggt accatatttt cacgtaaacc acctgtaaag ctgtgaagac
     7681 gggctgcacc tgtattttca cctgcaaagt ggaggtattc cgtgatgttt cctttttcac
     7741 cattgatgat tggaaattca gcatctggtg agaaaccaaa gtctggcttg gcgagtccta
     7801 cgtgctcgaa gtagtagtcc atatctgccc agcctgattc ttcgtctgtt ccaacgatga
     7861 agcgaacttt cttagaagtt ggaaggccca attctttgat gattttcaaa ccatagtagc
     7921 aagctgttgt aggtcccttg tcatctgaag caccacgcgc ataaaggcga ccatctttga
     7981 tagttggtgt gtaagggtct gtgtcccaac cgctaccagc tggaaccacg tccatatggg
     8041 caaagattcc gagaacttct tctccatcac caaactcaaa atgtcctgca tagttatcaa
     8101 catttttagt tggataacca tcacggtctg cgatttcaag gaatttttcc aaggctttta
     8161 ctggaccagg tccaaatgga tgttgggcat cagccttgct atcatcacgt tctgagttga
     8221 tttccaaaag gctaaacaag tcagccaaga ggtcttcttt gcgtttttct acttctgctg
     8281 taaaatcaat tgctatcatt ttttcttctt cctatctttt ttcgatgatt tcatctactg
     8341 gcaagcggta gcttggttcc aatttgtcgt ctgtgtaacc cactgtgatc aagagttctg
     8401 ggcggaaacg gtcttcaatt tccaaaacct cattgacttt tgatttgtca aaaccaagga
     8461 taatattgga accaattcct tggtctgtaa gagcgagaac caagttcata gcaaccaaac
     8521 ctgcattgag tgctaggtag tcgctgactt gttgttcatt gtagcgtgca aattcagctg
     8581 gcaaattttt catgaagtat tgaagttgtt cttctgagaa attgttagca ccaccaactc
     8641 gggcaatctt acgagcgcgt ttggcaaggt ctgtatctgt aaatagggca atggttacag
     8701 gtgctgatga tacctgctca aagtttgaac cataagccaa ctttgccagt tcagcatttt
     8761 tctcacgaac aactacaaat ttccaaggct ggctgttgtg ggcgcttggc gccaaggttg
     8821 caatttcgat agccgtacgc acatctttta gatcaacagg cttatcagtg aaatgcttgg
     8881 tcgcatgacg ttttttattt aattcaagaa atttcataat cgatttcctt ttctaattct
     8941 actgcttcca ttctaccata atttgaaaga gcttgcaggg atttttcatg attaagtttt
     9001 tctatcacag acataaaaga tatatattgg tttatcagga aagtttctga taaactagca
     9061 agtactttac atttgaatgg agacagtatg aaaaaattta gcctattact agctatccta
     9121 ccatttttgg ttgcctgtgg gaatcaagct acacccaaag agactagcgc tcaaaagaca
     9181 atcgtccttg ctacagctgg cgacgtgcca ccatttgact acgaagataa aggcaatctg
     9241 acaggcttcg atatcgaagt tctaaaggca gtagatgaaa aactcagcga ctacgagatt
     9301 caatttcaaa gaaccgcctg ggaaagtatc ttcccaggac ttgattctgg tcactatcag
     9361 gctgcggcca ataatttgag ttacacaaaa gagcgtgctg aaaaatacct ttactcgctt
     9421 ccgatttcca acaatcccct cgtccttgtc agcaacaaga aaaatccttt gacttctctt
     9481 gaccagatcg ctggtaaaac aacacaagag gataccggaa cttctaacgc tcaattcatc
     9541 aataactgga atcagaaaca cactgataat cccgctacaa ttaatttttc tggtgaggat
     9601 attggtaaac gaatcctaga ccttgctaac ggagagtttg atttcctagt ttttgacaag
     9661 gtatccgttc aaaagattat caaggaccgt ggtttagacc tctcagtcgt tgatttacct
     9721 tctgcagata gccccagcaa ttatatcatt ttctcaagcg accaaaaaga gtttaaagag
     9781 caatttgata aagcactcaa agaactctat caagacggaa cccttgaaaa actcagcaat
     9841 acctatctag gtggttctta cctcccagat caatctcagt tacaataaca ctcttcgaaa
     9901 atctcttcaa accacgtcag ctttatctgc aacctcaaag ctgtgctttg agcaacctac
     9961 ggctagcttc ctagtttgct ctttgatttt cattgagtat aagatatact aaaagcgatt
    10021 ggaccagcca atcgcttttt tagtttgcat tggctatttt aggaaactct tacaaaaaat
    10081 caaaaaaatt cttcacatcc tctacatacc catgcttttc tattaagctg gctaaaagtt
    10141 ccagattgtg cccctgatag ttatcgtcac gacgcagttc ttcatacatt tcaataaagg
    10201 gaagcccctt ggacttggcc aattctaact cagcctcgta atcataagca actttacgaa
    10261 attggatatt gaccaattcc ccatcttcaa cttctatcac ggcatactgg gcacggtgat
    10321 tttttaacgc ctcccaatta aaatagggca tgccaatcga ccctggattg atgatttgtt
    10381 gcccttgact tccataacga agcaactgct tgtgaacatg accataaact gccacgtccg
    10441 tttccgcatc tagcagttgg tcaaatttct ctgtatcatt ctcaactagc aagtcaccac
    10501 catagttctt atttggcaaa ttatgagaga tagaaaagcg cagtccagca atttctttct
    10561 tttccagcaa aggcaagctt cgtagccaga cagtcgttgc aggatccatt cgctccatca
    10621 aaaactgagt cattcgcatg agctggattt cctgtgggtc ttctaagcca tattgcccat
    10681 ctaaagcctc aaggacacaa tcattccaat tgcctcgaac acttgccgtg ataggaagtt
    10741 cctttaacag agcgaccaag tcatttgcac ctgaaccagg gaggaaaatg tctcccatga
    10801 gccaatattc actggctcct tgagttttag catctgcaat cactgcttct agcgccgtcg
    10861 cattgccatg aatatctgat aaaattgcga ttttatggtt tattgtggtt tccttccgtt
    10921 tggtaatcta ctctttcttc cgccacttga agcaagattt ctgtttcctg cgggttcaac
    10981 tttctttgca cagcctctgc tactgctctt ggtactccaa cttcgacaat ctcatccaca
    11041 ctggcttcct tgattttggt cagagacttg aagtgcctca tgagattttg cttgcgttta
    11101 ggtcccagac catcaatccc atccaattga gatgagaaag aatttttgga gcgcagttgg
    11161 cggtggaagg taatggcaaa gcggtggacc tcatcttgaa tgcgttggag gaggaaaaat
    11221 tcctgagaat tgcgagacaa gtccaccact tccagcggat ctccaaagag caattcatgg
    11281 gtttggtgct tatcattctt ttgcagacct gcaattggaa tatccaagcc cagttcttct
    11341 tggatgactt gcttagcaat attgacttga ccttgccccc catcaatcac aatcaaatct
    11401 ggaggagtca aagcctcacg ctgtactcga ccatagcgtc ttcgaatgac ttctctcata
    11461 ctagcatagt cgtccggccc aacaacggtt tttatcttgt acttacggta atctttttta
    11521 cttggcctgc cgttaacaaa gaccaccatg gctgaaacag gactggtccc catgatgttg
    11581 gagttatcga aggactcgat gcgaactgga gtcggaattt ggagcaaacg tcctagattt
    11641 tcaatagctc cttgggtctt ttcgactgat ttttctagca ggttaaattt ctgctccaga
    11701 ctaacacgtg cattttttat ggctagattg accagctgtt ttttctctcc acgttggggt
    11761 ttgagaatct tggtatccac caaagccttg acagcttctt cgtcaatatc ctgcggaatc
    11821 agtacctcat tgggaactag gtgagatttt tcttgataga attgtcccac ataggtcaag
    11881 aaatcctcat ctggatcatt gaagtagggg aagagattga catcgcgctc gatgagcttg
    11941 ccctgacgaa caaagaaaac ctgcacacac atccagccct tatccacata gtagccaaag
    12001 acatcgcgat tttggagatc cttagccatg acccgttgct tggttcgaag cgttccaata
    12061 gcctgaatca ggtcacggta ttccgccgca cgttcaaact ccatactttg tgctgctact
    12121 gccattttac tcttgagatc atcgatgatt ttgtcatcct gacctttcag aaaatcagac
    12181 acctcctgag ccatagactt gaaataagcc tcatccttct tacagatggt gtgggccata
    12241 cactggccga tatggtaata aaaacagacc ttagagggcg ggttggtaca ttttcgaaaa
    12301 gggaaaatcc tatctagaag tcgcttgatt tcattggctg cccccacatc tggataaggg
    12361 ccaaaataaa gaccaccgtc ctttttgacc tgacgagtaa tgataagccg tggatagcgc
    12421 tcattggtga ttttgatgaa aggataggac ttgtcatcct tgagcatgat attgtacttg
    12481 ggcttatttt ccttgatcaa gttgatttcc agcagaagcg cctcaatatt ggactcagtg
    12541 acgataaatt caaaatccac aatttcagac accagagcct ctgtcttggt atcatgaatt
    12601 ccacgaaaat aggaccgtac tcgattacgc agatttttag cctttcctac atagataatg
    12661 gtgccatttt tatccttatg aatgtagcaa ccagggctgg tcggcaagag ctctagtttt
    12721 gatttaatca agttgttcat agttccatta tagcaaaaaa agtagggaaa gatagtaccc
    12781 tactcactag tctcatatat ttttcggagg tttgcaacat cctcttcctg gataccataa
    12841 aaggaacctg ctggttgcat gacagacttc tcatctgtat ggtccaagcc aatcgcatga
    12901 cctaactcat gttctgccgt atggacaagg cgttcatagg agtagccata gtatggattg
    12961 gacaaataat aatgattcaa ccgcaccgtt acggacaaga attgccctgt taagagatta
    13021 gtttgacttt ccgcctctcc tgccacagga gtgcctccgt cgttcatctc cgtagccgta
    13081 atatccgcct tactagactc agtcacgagt tcaaagttaa aagcaccagt ttgattccag
    13141 ttctggattg cttctaaata agcctcttga aagcgtgaat ccatctgcgg atccaggtaa
    13201 atacgagcag aggcctgtgc ccaccttcct tcagaatgct ggtgactatc tgtctggctt
    13261 aacttaggca gttgccctgt tttctcccat tggtcaatac tttgttgacc catttttact
    13321 gaccgttctg cttgctttag cgctccttga aaatccccgt tcagatacca gagaagtccg
    13381 aaagcaagca cacataagag cacaactatc caaaccagac gccaaaacaa acgccacaca
    13441 aaagaaaaga aagcccctat caaacgaaaa agccagcgca tgtctctcca cctttctagc
    13501 aaataagaat tattttacta aaagaagcta aaagaaatct aaatactgac tttttcatct
    13561 taacgtccta ctattttttt gagtaactgg atagctttgt attttaaagg cgatggatgg
    13621 taacggaaag tacctgcttt gcgtacaata tagccattaa aattctgttt aaaacgcaaa
    13681 acaccatcac ttccatcaaa aatcccttga atgcctagga agttgtattt aggtattcca
    13741 cgttttatgc tttccaacat aacatatttt tgaagcagtg caggggcata gaacttatta
    13801 aactcagtgt aggaaccact aaagagataa gtcgtttcct gaggcatata aacaaataaa
    13861 ctcccagcta aaacaatatc ttcttctcca tatttttcaa tcaagtctcg cgcttctgct
    13921 tttcgaactt caaacgtttc aaattgacta gaatattctc tcagttgatt ttgttttttc
    13981 tcagaatgag gatttttact caaatcaagt cgcaacttgt ccaagttttc ttctagttta
    14041 ctttgttcac cttgcaattt gctcatatac tccgaaaaat tcaagcttgc tatgagaaac
    14101 tccgcttgtt ctccaaaagt atcataaaaa tgctcataat attctaaact tttatcacta
    14161 tattctctac gttcagaggt ttcttttgtt atattcttaa aaatcgatag ttcttcacgt
    14221 tttaactttt tcaaccgaat gccaaaggtt tcagcctttt tcaccaaggg tttacccttt
    14281 ttgctaaaac ttttaagcaa actcttttca gttaattcag ttaaatcttt atagtataac
    14341 caatctggtt ctccacctgg gtaacctgtt gttaagccat caaattgata acctaaatca
    14401 gtcaaacctt gaataatact ttttttctca gcatctattg gattaccttg gctatcaaaa
    14461 gtttgataag tttcataagg ttttacaagc aactctaata caccattttg cttggcatat
    14521 tcttttaact ctgcataaaa aactggaaga gcatcttgtt gggtataaat cggccccgaa
    14581 ttgagttcca tatgcagacc acccagcatg ggcaagctat aaaccagagc tgcaacttga
    14641 atttctcctt cttgtttcaa agcaagataa acaattcgag cccctctttt ttctagcaaa
    14701 tcccccatct ggacagattg cataaaggaa cgagaagaaa cctgatcaga ataagtctga
    14761 aactcttctt tcgtgagtgt tgttagtgcc atatacttac tttctatgtt tttttcttaa
    14821 tgttttacgg aaatcaagag caagtcttaa cagaggatag agaggatgag tgggcattgt
    14881 aaattcaccc aagtattctt caatcgttgg attaaatttt tccttaaaat gataaagtcc
    14941 accattgaga gagttttcaa caccacctaa attttgccag accatacctc gctcaaaggc
    15001 atagcgagcc gtttcatacc atgttaaaat tggtgcattg taacgtttaa aatcatcatc
    15061 cataccagca tatatattga cagaggtagt accaaattcc aaactcaaag tagccgctaa
    15121 aggaactctc gcttgaccta catctatata ttcctgcaag aaggtcaatt cctctaacaa
    15181 acgttctttt tccttcttct gcgcttctac ttttgaagtt cgagtcgact cagtaaaggt
    15241 ctcttccaag gctctatttt tcgctaactg ttcttctaac tcttgcgaac gtttagaaac
    15301 atccaaggtg gccaaggtga tataggcctt gtccttaaaa ttatctaaca attttttata
    15361 ataggcttca ttcctcaaat gaatctcttt tcgcttctca gtttttttca tcaactccga
    15421 aaatgaatct aatagttcca gtccaccata ttgaatctca agccctttgt ttcgtgctgt
    15481 tcgaatagcc tgttttgttg acttggaaag tttatcttct tcaaaatttt ccttgtatat
    15541 tttcgcctga atacgaggtt gaatggtgtc tcccatttcc tccgtttttc ctgaccacct
    15601 tactcccatt tgttgcaaac tatcaataat agccagattt tcaggaaatt ctgtcttttc
    15661 ctgattgatt aaactttgag ataggcaaat acttgggtca aaagtcacaa aaaccgctct
    15721 cttactgcga gcataggact taatagactg aatggcaaaa ttcaagagtt ctttatcccc
    15781 ataatccaat ataggtcctc ttgggatgta aaacatttta tagcctagcg gaagagttct
    15841 aatcaaaata ctagctgtcg ccagtaattt ttcttccctg taaacaccaa acttctcatg
    15901 ttgccaatta gacttaactt cctcccaagc actactttgt aatacattgg ctaattcatg
    15961 ttctttgaca aactgatcat attctaatgt gggaatgcca atttgataac ggtacatttc
    16021 ctactctctt tcctccagta ttttattact attctactac tttcgtttga aaagtctagt
    16081 gaaaacatat tttattttag ttctactccc cctatgctga agttcaaact aagtcagtct
    16141 ctcttctaat ttgaaatcaa ttggtagggt tgttaaaaaa acttccaatt gtttttccca
    16201 gtagtaccac tcgtgagttc cagcgctatg gctataggtc acatcaaaac ctagtttttt
    16261 gagatttttc actgcgagat tattggcttc gtacaagaaa tcctgttcgc cacaccacgc
    16321 ccaaagtttg gtctttttat ccgatttttt agccagactt tcaagagaat agggactagt
    16381 tgtccagtct ctaatctctc caaaaacacc tctccagtag gctggacttc ccagattttg
    16441 actttcagga gaaaagtttt gaaagctgag ggcacctgaa aaactagctg catgagaaaa
    16501 acgatttgtc gcaagagcca gtttgaagca gccgtaacct cccatagaaa gaccagcgat
    16561 aaaggtcttt tcacgcttgc tagtcatatt agggaagaag cgtttcagaa cctgtggcaa
    16621 ttcctctgct agagccgtgt agtagtcaaa accatactgg gtatcggtgt accaaccatt
    16681 gctggtattg ggcataacaa cgatgagatt agttcctcga agcaagcgtt ctacattggt
    16741 ccgcttaagc caactattat gatttccaga catcccgtgc aaaaggtaca agacgggaat
    16801 atcttcacac tctggttctt ccactcgatt ggcatcaggg tagaggacat tcacccccca
    16861 ctccatatcc aatacttgtg agtaatactc gattttcatt actgccatga ttttctcctt
    16921 ctatttttct ataagaaaaa gccgaaactc gactttctct ctgtttattt caacgattat
    16981 tttgcttcca tgactactgg taaaatagct ggacgacgct tggtttggtc aaagagatac
    17041 ttggtcaaat tatctcgaac cttcccttta agatctgccc agtcaaagtc atctccttga
    17101 agataatctt ctaccgtttg gttaatcaat tctgaacttt cacggagaat atcgcgactc
    17161 ttcttgagat aaacaaatcc gcgcgtatga acacgagccc tagccacaat tttcttctca
    17221 cgacggttga ctgtaatagc cacgatgaaa attccatcct ctgacaagat cttacggtca
    17281 cgaagaacaa catttccaac atcaccaatg gcattcccat caatcaagat atctcctgct
    17341 gaaaccgatc cagctggaac aaagtctcca ttctcgtaag ccatggtcgt ccccttttta
    17401 ggaatgaaga tgtgttctgg caacatccca actgccatgg cagccttagc gtgagcatcc
    17461 aactcacgat actccccttg gacagggaag aggtacttag gttgcaaaag attgatcatc
    17521 agctgcaaat cacgcacatt tccgtgccct gatacatgta aactttgggt aatcaatttg
    17581 acaaccccac ctgcctgata aatcatattt tccacacgcg caacaaaggc ttctttagca
    17641 atagacggag ccgtagcaat atagaccagg tccccatcct tgatttctac ataacgatgg
    17701 cgaccaatcg acatcttacg aagtccattg ataggttcac ccatacgacc tgtctcaaga
    17761 ataatcaact catggtcttc aaagcgagac atatctttag gcttaatcaa gagaatttcg
    17821 ttggctaaag acaacttctt aagacgaatc gctgtgcgga cgatattttc aatatcaaat
    17881 cctgtcaaga cgatacgtcg acctgtttta tccgcagcgt caaaaatctg ctgaatacga
    17941 gaaagattac tggaaacagc tgcaacgatg atacgacctt cccagtcagc aatagtttgg
    18001 gtaatttcat ccctaacttc actttcacta gccacctgaa tattgctgtc tgcattggcc
    18061 gaatcactga ggagagccag gacgccgtca cgaccaatct ctgccaaacg agcaaaatca
    18121 gttgcataag attcactagc cgtttggtca aatttgaagt cacctgtata aacgatgctt
    18181 ccttccgatg tcttcaagac aattcccaga ctctctggaa cggagtaagt cgtagggaag
    18241 aaggaaacca ctgtcccacc aaaatcaatc tccgtattct catcaatgac atggaaatca
    18301 ttaaatttct taacggcatc atttcctttg acaaagagct ttgccaactc aatggtcaac
    18361 tcagacccaa atacaggaac tttagcctct gccaagagat aaggtagagc accaatggca
    18421 tccgcatgcc cgtgggtcaa gaaaacccca gcaatacggt cgctattttc aaaaaggtaa
    18481 tccatgtttg gaatcaccac atcgacccct aattgttcat tttcaggata ttttaaccct
    18541 acattcaaaa caaaaatgga ctctccaatt tcagcaatgt acatattttt tccattctca
    18601 cgcacaccac caagtgttgt taaactgata ttactcattt ttcctccaaa atcttagttt
    18661 atcttgatta tagggcaatt ctaccctctt attctaaaag ttctgatact ttcagccgaa
    18721 tcttttccta ccattatacc atttttttga tgattttcaa aatgaaggtc tgttttcaaa
    18781 aaagagttga tttcccaact ctttcctaac ttctactctt tttccatcaa aaaatcataa
    18841 atttcttgca ccgtacccag cgccatcatt tcttggtctt taacggtttg tttgagattt
    18901 tggtaaattt gactttctcc tatctcccgc tttggcgcct ctttattgac tgtcatcaca
    18961 ccatctttta tcgtcacaaa gcctagttct tcaaatactt gaatcatctt gaccagcaag
    19021 atttgttgaa tattaagata tgcagccaaa tctttcagct tgtagcgaat atcaaactct
    19081 gggaactggt aaatagtctt gtacaattta gcaaactgat ctctagtccc ataacctgtc
    19141 agataatagg tcttgtcaat atcatttttg aaatagacag cagagaaatg ctgttcctga
    19201 aaaatggtct tcagctgagt aatatcctct ggaatgtttt ttacgacaac agcttcacta
    19261 gccgcaagat ttggcagttc tccaggaaaa tccaagactg gaacaccttc tggcaagact
    19321 gcattttttc cacgaatgtt aaaaagttga acaccttcca ctcgcgcatc caccatcatc
    19381 aactggaggg cagtttggcc attccattgg ttgacagaca atttaaccgc taactctaga
    19441 ttcttggttt gagaaaactc tgtcgcccat ctgccttgac caaaggctac cacttcaaaa
    19501 ctcgcctcac ccttggaaat tttcagcttt agatgggcat tacctgcccc catagtacga
    19561 gcactttcga cctgaaaatt cttgatataa aaaataggtt tctgattatc cattccaaaa
    19621 ggagctaaac gttcaaaact tttgaccgtt tccaagctaa gtgcctccaa atccaactct
    19681 tcatctaggt ttaacttatt cttgccacca gcatctgcac ctttttcacg aacataatct
    19741 tccaaaacct gagataaatc tgagagttgc tcaacttcca gcgtcatacc cgctgcacct
    19801 gcatgacctc caaaggcgat gaagaggtct cgatggggat ccagagcttc aaaaatatcg
    19861 accgcttcca cactacgagc actgcccttg gcacgaccgt cttctatatt aagaacaatg
    19921 actgtctgtc ccaattcttc caataaacga ccagccacga ttcctagaac cccaggattc
    19981 cagccttcct tggccaagac ctgaaccttc ttctcaggat ccaccatggt cttggcttct
    20041 tcatagatag actgaacgat ttccttgcgc tcttcgtttt tctggtgaat cataagggca
    20101 atctcatgcg cttcctcatc atcaaatcca gtcaacaaat caatggcagg attgggatca
    20161 tccaagcggc ccaaggcatt caaacgagga gcaatctgga aaccaaccgt ttcttctgtt
    20221 acttcgttgg cagcaatccc agccatgtcc agcatttctt gcagaccaat gcgctgggta
    20281 tgacccaaca tttccagacc atattgaact aagatacgat tttcatccgt cagactcacc
    20341 atatctgcaa tagttccaat agcgaccaaa tcaagcaatt ccacttgcac ttcttctaac
    20401 agggcacaag ccaacttgaa agcaactcca caaccagcca aatatttaaa aggataatcc
    20461 gcatctggat gttcaggatg gacaatagca taagcatctg gcagggtttc aggcatggaa
    20521 tgatggtctg tcacaatgac atctactccc atagactgag ccaatgcaat agcctcatga
    20581 ccagcaaccc cattgtccac cgtcacaatc aaggaaattc cttcttgctc gataaagtat
    20641 ttataaacac tagcattagg gccatagcca tcggtaaaac gatttggcag gtaaactcgg
    20701 cactcagcac caagttgttc caaactttcc ttcacaatag aagccgaagt catgccatcc
    20761 gcatcatagt ctccataaac gagaatattt tccccttctt caatagcctg acgaatccgc
    20821 tccactgcct tgtccatatc atggagcaga taagcatcat gtaagtcctc caaggaaggt
    20881 tctaaaaact tcttcagact ttcttggtcc tgaatccctc tctcaaacaa taaccgagcc
    20941 acctcaggac ccagtccagc cttcttggct atctttgtaa aatccgcatc ttctacctgc
    21001 agggcaaact gccattcata agtaggtgtt atcaaaaaga catccactct ttctaagaat
    21061 tctattgctt cattataaca tgatttagac gttttctcta tccagattgc ttttttataa
    21121 cattttatag tatattgaaa ctagaatagt acacctctac ttctaaaata ttgttagaaa
    21181 tcgatttgac tgtcccgatc gatttgtcct gttcttattt cactatagtg aattttttca
    21241 gatatggttt gacaagaaca ttctttcatt gtagaatcgt gttataaaat ataacacaaa
    21301 ggagatctct catggcttta gtagaattta aaaacgtcga aaaatattac ggagactacc
    21361 acgcactccg caacatcaat ctccgttttg aaaaaggaca agttgttgtc ctgcttggac
    21421 cttctggctc tgggaagtcc actcttatcc gtacgatcaa tggtttagag gctgttgaca
    21481 aaggaagtct cctagtcaat gggcaccaag ttgctggtgc cagccagaaa gatttggtac
    21541 ctcttcgcaa ggaagtcggc atggtttttc aacattttaa cctttatcca cacaaaacgg
    21601 tgttagaaaa cgtgacactt gcgcccatta aagttctagg aattgataaa aaagaagctg
    21661 aaaaaaccgc ccaaaaatat ctggaatttg taaatatgtg agacaagaaa gattcctatc
    21721 ccgccatgct atctggtgga caaaaacagc ggatcgccat cgctcgtggt cttgctatgc
    21781 atccggaact cctcctcttt gatgaaccaa catctgctct tgatcctgag actatcggag
    21841 atgttctagc agttatgcag aaactggcgc atgatgggat gaacatgatc atcgttaccc
    21901 acgaaatggg ctttgctcga gaggttgcgg accgcattat ctttatggcc gacggagaag
    21961 ttttagtaga tacgacagat gtcgataact tttttgacaa tccaagcgaa cctcgtgccc
    22021 aacaattcct cagcaaaatt atcaaccacg aaagtgacaa agtcaaataa ggaggcgcct
    22081 atgaaaaaaa attcttttta tcagcattat tgattagcct tttcggcctt gctgctgcca
    22141 aaccagtcca ggctgatact agtatcgcag acattcaaaa aagaggcgaa ctggttgtcg
    22201 gtgtcaaaca agacgttccc aattttggtt acaaagatcc caagaccggt acttattctg
    22261 gtatcgaaac cgacttggcc aagatggtag ctgatgaact caaggtcaag attcgctatg
    22321 tgccggttac agcacaaacc cgcggccccc ttctagacaa tgaacaggtc gatatggata
    22381 tcgcgacctt taccatcacg gacgaacgca aaaaactcta caactttacc agtccctact
    22441 acacagacgc ttctggattt ttggtcaata aatctgccaa aatcaaaaag attgaggacc
    22501 taaacggcaa aaccatcgga gtcgcccaag gttctatcac ccaacgccta attactgaac
    22561 tgggtaaaaa gaaaggtctg aagtttaaat tcgtcgaact tggttcctac ccagaattga
    22621 ttacttccct tcacgctcat cgtatcgatg ccttttccgt tgaccgctct attctgtctg
    22681 gctacactag taaacgcaca gaactactag atgatagttt caagccatct gactacggta
    22741 ttgttaccaa gaaatcaaat acagagctca acgactatct tgataacttg gttactaaat
    22801 ggagcaagga tggtagtttg cagaaacttt atgaccgtta caagctcaaa ccatctagcc
    22861 atactgcaga ttaaggagga caccccatga tagatttatc atcttggaca gcctattttc
    22921 aggattttgg acaatttttc aatggtttcc tctttactct tgccctagcg attggatcct
    22981 ttatcctcgc catggtctta ggaatcttct ttggtgccat gtcaaccagt aaacgtccaa
    23041 ttttacgcat tttagctcac atctttgtgg aattttacca aaacactccc ctcttggtgc
    23101 agtttgttat tgttttttat ggcctacctc ttatcagtga ccatactatc atgattccaa
    23161 tttattggac agctgttctc tgcatgggac tctatcacgg cgcttatatc gctgaggtta
    23221 ttcgttcagg gattcagtct attcctagtg gtcagatgga ggccgccttg tcgcaaggtt
    23281 ttacctatat cagtgccatg cgcttgatta tcttgcctca gaccttccgc atcattctcc
    23341 ctccattgac caaccaaatt gttaacctca tcaagaacac ctctactgta gctatcatct
    23401 ctggagtaga cttgatgttt gtgactaagt cttggtcggc tctcaacgga aactatatcc
    23461 cagccttttt aggtgctgct cttctctact ttgctctatg cttccctgtt gcccagtttg
    23521 gtcgcaagat ggagcaagcc aacaaaaaag cctattcact ttaggaggtt actatggaat
    23581 ctattttaga agttttaacc ccagataacc tagtctttat ctttaaagga tttggcttga
    23641 ccctctatat ttctctgatt gccatcatcc tctctactat catcggtacg gtgctagctg
    23701 tcatgagaaa tggcaaaaat cctgtcttac gcattatttc cagtatttat atcgagtttg
    23761 tgcgcaacgt tcccaacctt ctctggattt ttactatctt tttggtgttc aaaatgaaat
    23821 ccacaccagc aggtattaca gcctttactc tctttacatc agcagccttg gctgagatta
    23881 ttcgaggcgg tctcaatacc gtagacaagg gacagtacga agcaggaatg tcacaaggct
    23941 tcacctcagc ccaaatcctc tactacatca ttctcccaca agccatccgc aaaatgctac
    24001 cagccatcat ttctcagttt gttaccgtga ttaaggatac cagtctcctc tactctgtta
    24061 tcgccctaca agaactcttt ggagccagcc aaattctcat gggccgttat ttcgaaccag
    24121 agcaggtctt cagtctttgc atcctgattg ccctcatcta cttcagcttt aacctagcaa
    24181 tttctagcct gtctcatatg ctagccaaac gttggcaaca agctgcagaa taatactctt
    24241 cgaaaatctc ttcaaaccac gtcagcttca ccttgccgta tatatgttac tgacttcgtc
    24301 agttctatcc acaacctcaa aacggtgttt tgagcagcct gcggctagct tcctagtttg
    24361 ctctttgatt ttcattaagt ataaacagcc actctccagt tcaattggag agttttttga
    24421 tgagagtaga tatttataga cctcaatttg acaccataca ttttctatga taaaatgtaa
    24481 caaattcatt tacaacaaat cgaaatctaa atgaaatgga attttctatg aaatcagtca
    24541 aaggactact ctttatcata gctagtttta tcttgactct tttgacttgg atgaacactt
    24601 ctccccaatt catgattcca ggactagctt taacaagcct atctctgact tttatcctag
    24661 ccactcgtct cccactacta gaaagctggt ttcacggttt ggagaaggtc tacaccgtcc
    24721 acaaattcac agcctttctc tccatcatcc tactaatctt tcataacttt agtatgggcg
    24781 gtttgtgggg ctctcgctta gctgctcagt ttggtaatct tgccatctat atctttgcca
    24841 gcatcatcct tgtcgcctat ttaggcaaat acatccaata cgaagcttgg cgatggattc
    24901 accgcctggt ttacctagcc tatattttag gactctttca catctacatg ataatgggca
    24961 atcgtctcct tacatttaat cttctaagtt ttcttgttgg tagctatgcc cttttaggct
    25021 tactagctgg tttttatatc atttttctat atcaaaagat ttccttcccc tatctaggaa
    25081 aaattaccca tctcaaacgc ttaaatcacg atactagaga aattcaaatc catcttagca
    25141 gacctttcaa ctatcaatca ggacaatttg cctttctaaa gattttccaa gaaggctttg
    25201 aaagtgctcc gcatcccttt tctatctcag gaggtcatgg tcaaactctt tactttactg
    25261 ttaaaaattc aggcgaccat accaataata tctatgataa tcttcaagcc ggcagcaaag
    25321 taaccctaga cagagcttac ggacacatga tcatagaaga aggacgagaa aatcaggttt
    25381 ggattgctgg aggtattggg atcaccccct tcatctctta catccgtgaa catcctattt
    25441 tagataaaca ggttcacttc tactatagct tccgtggaga tgaaaatgca gtctacctag
    25501 atttactccg taactatgct cagaaaaatc ctaattttga actccatcta atcgacagta
    25561 cgaaagacgg ctatcttaat tttgaacaaa aagaagtgcc cgaacatgca accgtctata
    25621 tgtgtggtcc tatttctatg atgaaggcac ttgccaaaca gattaagaaa caaaatccaa
    25681 aaacagagct tatttacgaa ggattcaagt tcaaataagt aatcatactc tcctgggatt
    25741 tcccaggaga gttttttata gccaaatgaa ataaaaccgg aacgatggaa ttttggcatt
    25801 caaatcaatt gataagaata ttttatagtg gagtgaaata ggatacgaac aaattgatta
    25861 ggaaaatcaa atgaatttat agaaatcttt tagcagttat gttgtcctat tctagtttca
    25921 aaacgctata gaagcagcat tgtgctagtc tagattcagt ttactatact aaaacgagta
    25981 gcttgaaatc aaaaaaccca ccctcacagg caggttttat ctgtattatt cagctagatt
    26041 atgctttacc ttctgaaccg aatacgtcga tacgttcttc aaccgatgct tggatagctt
    26101 ttacaccgtc agccaagaat ttacgtgggt cgaagagttt tttcttgtcg tattctgctt
    26161 cgtttgcttc gtagtcacga gcaaatttac gagttgcgtt agcgaatgcg atttggcatt
    26221 ctgtgttaac gttaactttg gcaacaccaa gtttgatagc tgcttggatt tgctcatcag
    26281 gaatacctga tccaccgtgc aatacgattg ggaatcctgg aagagcttct gtcaattttt
    26341 gcaagtggtc aaggtcaaga ccttcccagt ttactgggta agggccgtgg atgttaccga
    26401 taccagctgc caagaagtcg ataccagttt caaccattgc tttagcgtct tcgattggag
    26461 ccaattcacc tttaccgatg attccgtctt cttcaccacc gatagtacca acttcagctt
    26521 ctactgagat acctttagcg tgtgcttttt caacaacttc tttagccaat ttaaggtttt
    26581 cttcaactgg aaggtgtgaa ccgtcaaaca tgattgaagt ataaccaact tcgatacact
    26641 caagtgcatc ttcgtagtga ccgtggtcaa ggtggatagc tactggtaca gtgataccca
    26701 ttgattcaac aaggttagcg atcaagttgc gagcaacttt gtaaccaccc atgtatttag
    26761 cagcacccat tgaagtttgg atcaaaactg gagctttttt agcttctgct gcgcgcaaga
    26821 tagcttgagt ccactcaagg ttgtttgtgt taaatccacc aactgcataa ccgttgtcac
    26881 gggctgcttg gacaaatttt tctgctgaaa cgattgccat tttatcaggc ctcctgtata
    26941 tttttatggg tcatcccatt tacattgttc attttatcac tttttgccaa aaaaatctag
    27001 tttttcccgc agtttcgatt gattttcttc taactccatc tatgtaaacc ctttctctcc
    27061 ctagtcttgg acgacttttg gaaaatctat aaagaaggtt aaacgattct cctccatctc
    27121 gaaacgataa gctaattttt catgttctaa tagactctta accacaaaga gccccatacc
    27181 agaccccttg accttgcgac tggcattgtc agaaaaagac tgggctagtt tttcttgttc
    27241 ctctgagcta cagctatttt cgataaaaag ttctccttct ctttctccaa ttcgaactaa
    27301 gccacctgga acagagtgct taatggcatt gctgatgaga ttagaaagaa tcaacttcat
    27361 aactgatggg tttagataag cctgctgatg ggtcaaacta ttgtctatct ggagctctct
    27421 ttccttggct agcaaggcat aatctttgac cagattttgc gtcatctgga ggaggtcaat
    27481 tgtttcccta tcatctcgca attcctgcac agaagagagg gaaagtatct gcagaacatg
    27541 gtgattgagt tcatccacaa tccccaaggc aactcccaga tactggtctc tatccttata
    27601 acgaccgata ttctctctca tattttcgat taggattttc aaactagcca gcggtgtttt
    27661 caattcatga gaagctcctc gtaggaattc gaccttcatc ttctccagct ggagaatggc
    27721 ttcattcttt tcatgcaagt ccgcaataac agtcaagaga tgctggtaga ggctattgat
    27781 ttgttccttg agattaccta tctcatcctt agaatccacg cgcaatcgca cttgggaatc
    27841 caggtccatc atccgacggg tcacccgctt gatttccaag atcggtgcaa caatagtccg
    27901 agcgtagatg taggccacca agagggaaat cagaaaggag gccagcaagg tatagggaag
    27961 aaactggaga ctgatttgct ccgcttcctt ttgtaaatcc atggaagcta gaaactggag
    28021 aatcatagta gcaccgtctt gcgttttcac ctcgcgctcc tcaataaaga gagaggttgt
    28081 ctggcggtct gtgtccagag gaagactgtc cttgacttct aacttgtcct cggtcatctc
    28141 acctttgacg gtccccttga tatcactagt ctgggaatac aagtctaaca cttgctcgat
    28201 actctgccta tctttccctt ctagggactg ggcaatggct gttgcctttt gaccaatggt
    28261 ttcctgacga tgactcagat aagtcgaagg aaaaagaaaa taaatagcta aatgaaggca
    28321 gataaccaga acactaaata tcgagaaggt atagataaat atctttgcaa ataaacctgt
    28381 tcgtttcatt ttcgctccaa tttataacca acattgcgca cagtgaggat acaatccaag
    28441 tctagctttt tccgcaattc cttgatataa acatcaataa cacggtcaaa gggaacctca
    28501 tctgtcgctt tccagacggc atcgataatc tgagatcgag tcaaggcccg gccttcattt
    28561 ttcactagat agtccagaat ttccaactct ttggcattga taggcacttc ttgacctgcg
    28621 atgcttgcac tgtagctttc aaagtccacc ttggtatcct tgtaagaaaa gattcgtcct
    28681 gtatcgtagt agcgcttgaa aatcgcgtcc accctcactt ttaaaaggga gagggagaaa
    28741 ggtttttcca gatagccatc tgccaaagag gcaaaggcac tcatcttgta ttcctcatct
    28801 tgaaaagctg tcaacatcaa gacaggaacc tgactggttt tacgaatctc agctaggact
    28861 tctaagccgt tgagcttggg catctggata tccagtaaaa ccagggccac ctcatagcta
    28921 gaaaattgct ccagagcttc ctgaccgtcc gctgcctcaa tagtttcata gccacaatcc
    28981 gtcaaataat cactgacccc ctcacggatc atctcttcat cttctacaat taaaattttc
    29041 atactttaac tgctctctat tttttatttt tcttagaata aatacctact ctattttcta
    29101 ttatagtctc ttgctggcct tttgtctgca agcaactgac cactagataa aacgttgtga
    29161 aattcctttc tcataaattc cataacttta gtatattata tttaagcact aaagtacaaa
    29221 gaaagcaact gaaagcaatg attttcacca ctgctttcgg atttattttg aattgttaaa
    29281 tagccattcc tatccactat tcttgaatag aaacacaaga tgcaatcttt attctagact
    29341 cattttttca aatttattca ccatccagca agagctcttt tggttgtttt ctaaggagat
    29401 tgcttgaagc aagcgccata acgagaacca ctagaaccaa ggcaaggaca aaaatgatga
    29461 taaagtctga tgtctgaatg gaaatgtcta ggctcgacaa ggtcttgcta aagccatcta
    29521 cttctgcacc accaccaagg ttagaggctt gagccgcctt actagcctgt ttggcaacac
    29581 ctgaagtcac attggcaagg acagtgtttc caattgcacg ggcagtgtaa ttagctagga
    29641 agtaagcaga aactagagca gggatagcaa tcaagataga ttcggtgatg aattgaccca
    29701 agatacttgc ctgcttgagg ccgatagaga ggagaattcc cacttccttg cgacgggcgt
    29761 tgatccaaag gctgagcaag agggcaagga ggagaactga gaagctcaag ctaccccaga
    29821 agaggaggtt ggccatcttg tacataccag agatagattg ctcaagagct gggtagttag
    29881 aggagctctt gacgagtgtg tagctcttcc agttgatacc actgatgcca ttcaactctt
    29941 tcataacatc atccaagttc ttgtctgctg ttacaaagaa ggttgcgtcc ccataaatgg
    30001 ctgtgtcttc tgtgtatcca taaagttttg cagcagtgtg aatgtctgta atagctgtgt
    30061 tttcgtaaag ttcttgtgag taggttactg ctgacttatt atgaccatca aagagtccct
    30121 tgattgtcac ttcaactgtt tccttggctc ctttttcatt atctgcatcg tagatattag
    30181 agtccagttt aaccttgtcc cctactttcc agccgtgttt ggctgccaag tccttgtgca
    30241 agaggatttt atccttgtcg tcgttggtta agtgctctcc ttcgactagt ttataagaac
    30301 cagagacaaa cttgtcttct ttagaggagt cattgacacc tgtaatcatc aagctacttc
    30361 caaaacgctt ggcacgatca gcagtgagat tcttcttggt ttctggcgtt tcaatcaggt
    30421 catatccagt caaatctccg atagcgttga tacgtttgac ataagactcg atggccttgt
    30481 tttcggtgat ttttttgatg tcttcaccct tgatattccc agcaccacga ggcgttcctt
    30541 ggttgacgcg acgattgatt tgcatggaga agctattagt gatattttta aaggtctcct
    30601 gagaagcctt ggcagtagct cccttgattg acaagccgac caaactcaag ctcgccatga
    30661 ggagaataat caggaagatg acaatcgatt tgaaaaactt ccttgtaaca taggcaaatg
    30721 cgttgtgtaa catagattcc ctttctagat tttgttttaa tcattctatc aaaataagct
    30781 caaattattt actagtattg cgcgtttcag tcagtttctt atcctttaat tcaagtgtaa
    30841 tatctgacgc ttgtgccact tctttactgt gagttacgac aatcacacat ttacctgttt
    30901 tctgggcaag tgatttgagt agttcgacaa tatctccagc agttttagga tccagatttc
    30961 ctgttggctc atcagctaga ataactggag cttctgagac caaactgcga gcaatggcaa
    31021 cacgttgctg ttgaccacct gataactgga gaacattccg cttgatctgg ctttcatcca
    31081 aaccaagctc aagaagtgta tccttgcttg cctttttgtt gaccaagcgg atattttcca
    31141 gcggagaaag ataatctatc aagttataat tttgaaagac cagggaaata tggtgcatgc
    31201 gatggtaaga atagcccttc ttacgaatat cctctccttg aaaaaggata gaaccttcaa
    31261 caggactatc tagaccagca agtagggaca agagtgtgga ttttcctgct cctgactccc
    31321 caataatact gtaaaatttt ccaggttcaa aattataatc gatctgatat aggactgctt
    31381 cagcagtatt cttataacgg taggtaacat cttgtaattg taataaagtc atgatttctc
    31441 cttcttaact aatagatgat aaaatttctt tcggtgattt tctaaataag aataggaaac
    31501 aaagggctac agataagcaa ctaagcagaa ctagaaaaac ataggattct gcaaaagata
    31561 agatgctagt tgataaactg cttgctttgg ctagtgtatc ttgtaagctt gcctgatctc
    31621 cacttgctag tagagtttgg agtagataac ttgtgattcc gtttcctgca acaaatgctg
    31681 gaagcaaagc tccaagagat accaaaacta cctctaaaca gaattgtagg aagatcgagc
    31741 tcttgccttt tccaagtgca agtaaaatcc ccacttcata gacccgttct ctcaaccaga
    31801 gagacaaaac cagaattaag gctccagctc ctgctatcaa catcccataa aggaagatgg
    31861 tcaagaaggt ttggaaagtt gcaactgagt ctttgatttg ttcaaaagcc ttgttttcct
    31921 tttcgacttg gtagccttga ttttccaagg ccaagttttc tacctgcttc atgagtccgt
    31981 ccatttcctt aggattttct acatagaagc gtgctgcact gacttgagct tcactattgc
    32041 ccaaaagggt ttggctactt tcatagtctg taaagacttg attttcactg aagtcagaag
    32101 acaagcctgt gaatttctct tgttttttac cagaaaagat gccgataatc tcaaactcta
    32161 ctgtttgtcc ttttccagat tcagactgac cagcatccaa gccaatcttg tcatgaagtg
    32221 aaagaccgtt cttcttagcc aattcttcgt ggataaggat tttcttggaa tccccttttt
    32281 gaaggtgtcg cccttctttt agattgaaag ccgaactggt aaaggttaca tccttggatg
    32341 aatcctcaag agccgttaag ctaaccaagt tattgtctgc agctgataaa tcatcacgct
    32401 ccacgctctg ctcaccagtc actgcttcct tgtcttttag ttttgcgacc gtctcaagtt
    32461 caggagagac attttccagc cccttaatct tgcttacaga tgctaggtct gacaacttga
    32521 atgtctgacc attctctatc ttcttaatag aaaaagatgt attgagtgat ttataaagat
    32581 tgctttctac tgttttgttg gacttcatca gagtcaaaca ggctgaaatt ccggccaata
    32641 agaccaataa aatcagaaat aaaataaaac ttctcagtcg ctttctgctg acataagccc
    32701 aagatctttg gattggattc atttgtcacc tccatatttg taagactatt ataaaaccca
    32761 aatatgaaat gtttatgaaa tacgaaaaaa aatatcgagt aggggataat ctctagcccc
    32821 tctcacacca ccgtacgtgc cgttcggcat acggcggttc aactaacttt taacgcatgt
    32881 cgttcaaggt aataatccaa acacgaaacc tgttcacgtt tttcaaggac tggttttgat
    32941 atagcacgtt taagtaccga cttctgagct actatagtag attgaaacta gaatagtaca
    33001 tctcttcttc taaaacattg ttagaaatcg atttggctgc cctgatcaat tcgtcc
//
LOCUS       DAVBEO010000021        31002 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 009
            SAMEA1678075-rid20185393.denovo.021, whole genome shotgun sequence.
ACCESSION   DAVBEO010000021 DAVBEO010000000
VERSION     DAVBEO010000021.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678075
            Sequence Read Archive: ERR226392
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 31002)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31002)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980207.1
            Genome Coverage       :: 150x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:50:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 72 of 147
            Pseudo Genes (incomplete)         :: 72 of 147
            Pseudo Genes (internal stop)      :: 42 of 147
            Pseudo Genes (multiple problems)  :: 32 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31002
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678075-rid20185393.denovo.021"
                     /strain="KS 009"
                     /db_xref="taxon:1313"
     gene            complement(298..516)
                     /locus_tag="VQ543_000992"
     CDS             complement(298..516)
                     /locus_tag="VQ543_000992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001207345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET2611730.1"
                     /translation="MVLNYKPLWIQLAKKGLKKTDVIAMAGLTTNVMAQMGKDKPITF
                     KNLERICKALSCTPNDIISFEDNFSDEE"
     gene            complement(762..1040)
                     /locus_tag="VQ543_000993"
     CDS             complement(762..1040)
                     /locus_tag="VQ543_000993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000710796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2611731.1"
                     /translation="MKKDKEVYDKVCEYLSPHLNKDMEMLELACWFRVIIVIEANSYV
                     NIRSSRLLPKFKTQKINSWCAAYSIHFNNGYCKQHTNEFKDSLKSLIL"
     gene            complement(1254..2885)
                     /gene="rlmD"
                     /locus_tag="VQ543_000994"
     CDS             complement(1254..2885)
                     /gene="rlmD"
                     /locus_tag="VQ543_000994"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000914584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HET2611732.1"
                     /translation="MLKKNDIVEVEIVDLTHEGAGVAKVDGLVFFVENALPSEKILMR
                     VLKVNKKIGFGKVEKYLVQSLHRNQDLDLAYLRSGIADLGHLSYPEQLKFKTKQVKDS
                     LYKIAGIADVEVAETLGMEHPVKYRNKAQVPVRRVNGVLETGFFRKNSHNLMPLEDFF
                     IQDPVIDQVVVALRDLLRRFDLKPYDEKEQSGLIRNLVVRRGHYSGQIMVVLVTTRPK
                     VFRVDQLIEQVIKQFPEIVSVMQNINDQNTNAIFGKEWCTLYGQDYITDQMLGNDFQI
                     AGPAFYQVNTEMAEKLYQTAIDFAELKKDDVVIDAYSGIGTIGLSVAKHVKEVYGVEL
                     IPEAVENSQKNASLNKITNAHYVCDTAENAMKKWLKEGIQPTVILVDPPRKGLTESFI
                     KASAQTGADRIAYISCNVATMARDIKLYQELGYELKKVQPVDLFPQTHHVETVALLSK
                     LDVDKHISVEIELDEMDLTSAESKATYAQIKEYVWNKFELKVSTLYIAQIKKKCGIEL
                     REHYNKSKKDKQIIPQCTPEKEEAIMDALRHFKMI"
     gene            complement(2959..3933)
                     /locus_tag="VQ543_000995"
     CDS             complement(2959..3933)
                     /locus_tag="VQ543_000995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1002 domain-containing protein"
                     /protein_id="HET2611733.1"
                     /translation="MRKKLFLTSAAVLWAVTAMNSVHAATDVQKVIDETYVQPEYVLG
                     SSLSEDQKNQTLKKLGYNASTDTKELKTMTPDVYSKIMNVANDSSLQLYSSAKIQKLG
                     DKSPLEVKIETPENITKVTQDMYRNAAVTLGMEHAKITVAAPIPVTGESALAGIYYSL
                     EANGAKVPQANKDLAQEELKALSDINAENKDKSGYDANKLNVALADIKSGLAKAKESK
                     GNLTEEDVRKIVEDTLKNYKLDQVITGNQINIIINFALNLSKSDILSNADFTKTLNDL
                     KQSIVSQAGDSFKNINLNFDADKALEDGGNFLSSLWQALVNFFKSFGS"
     gene            complement(4007..4621)
                     /gene="pmp23"
                     /locus_tag="VQ543_000996"
     CDS             complement(4007..4621)
                     /gene="pmp23"
                     /locus_tag="VQ543_000996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000476388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall hydrolase Pmp23"
                     /protein_id="HET2611734.1"
                     /translation="MFKRIRRVLVLAVFLFAGYKAYRVHQDVKQVMTYQPMVREILSE
                     KDTPANEELVLAMIYTETKGKEGDVMQSSESASGSTNTINDNASSIRQGIQTLTGNLY
                     LAQKKGVDIWTAVQAYNFGPAYIDFIAQNGKENTLALAKQYSRETVAPLLGNTTGKTY
                     SYIHPISIFHGAELYVNGGNYYYSRQVRLNLYIIKCFTLFSTSG"
     gene            complement(4621..5595)
                     /locus_tag="VQ543_000997"
     CDS             complement(4621..5595)
                     /locus_tag="VQ543_000997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein"
                     /protein_id="HET2611735.1"
                     /translation="MDIYIKKAIIHQFSPDDTELFLADKFLNITPKIEEYLRKKIEHV
                     YSDEAKTGIFEEENPFFNHITDDLLETSVTLANLWKEEFSISENLKTNDLIFVQFSKE
                     GVEHFAFLRIALRETLTHLGGEVDNPIKLTQNNLPGFGTGADEALVVNLQSRKYHLIE
                     KRIKYNGTFLNYFSDNLLAVAPKISPKKSIKELEKTAQRIAESFNTDDFQFQSKVKSA
                     IFNNLEESNELSPEKLANDLFDNNLTARLSFIDQVKEAVPEPVQFDEIDASRQLKKFE
                     NQKLSLSNGIELIVPNNVYQDAESVEFIQKENGTYSILIKNIEDIQSK"
     gene            complement(5603..6859)
                     /locus_tag="VQ543_000998"
     CDS             complement(5603..6859)
                     /locus_tag="VQ543_000998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HET2611736.1"
                     /translation="MIFDKDDFKAYDADLWNAIAKEEERQQNNIELIASENVVSKAVM
                     AAQGSILTNKYAEGYPGRRYYGGTDVVDVVETLAIERAKEIFGAKFANVQPHSGSQAN
                     CAAYMSLIEPGDTVMGMDLASGGHLTHGAPVSFSGQTYNFVSYSVDPETELLDFDAIL
                     KQAQEVKPKLIVAGASAYSQIIDFSKFREIADAVGAKLMVDMAHIAGLVAAGLHPSPV
                     PYAHITTTTTHKTLRGPRGGLILTNDEELAKKINSAIFPGIQGGPLEHVVAAKAVSFK
                     EVLDPAFKEYAANVIKNSKAMADVFLQDPDFRIISGGTENHLFLVDVTKVVENGKVAQ
                     NLLDEVNITLNKNSIPYETLSPFKTSGIRIGAAAITARGFGEEESRKVAELIIKTLKN
                     SENEAVLEEVRSAVKELTDAFPLYEE"
     gene            complement(6921..7352)
                     /locus_tag="VQ543_000999"
     CDS             complement(6921..7352)
                     /locus_tag="VQ543_000999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000942930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET2611737.1"
                     /translation="MLRDLQETDVKAICDINQEALGYTFSPEETASQLARLSQDSHHF
                     LLGYEDAANHVLLGYVHAEVYESLYSKAGFNILALAVSPQAQGQGIGKSLLQGLEQEA
                     KRCGYGFIRLNSANHRLGAHAFYEKVGYTCDKMQKRFIRIF"
     gene            complement(7354..7956)
                     /locus_tag="VQ543_001000"
     CDS             complement(7354..7956)
                     /locus_tag="VQ543_001000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000969297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonylcarbamoyl-AMP synthase"
                     /protein_id="HET2611738.1"
                     /translation="MMDRIRQELENGGAVVLPTETVYGLFAKALDEKAVDHVYQLKRR
                     PRDKALNLNIASFEDILHFSKNQPTYLQKLVETFLPGPLTIILEANDRVPYWVNSDLA
                     TIGFRMPSHPITLDLIRETGPLIGPSANISGQASGVTFEQILKDFDQEVLGLEDDAFL
                     TGQDSTIVDLSGDKVKILRQGAIKREDILARLPEISFEEA"
     gene            complement(7940..8779)
                     /gene="prmC"
                     /locus_tag="VQ543_001001"
     CDS             complement(7940..8779)
                     /gene="prmC"
                     /locus_tag="VQ543_001001"
                     /EC_number="2.1.1.297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000761890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor N(5)-glutamine
                     methyltransferase"
                     /protein_id="HET2611739.1"
                     /translation="MKLAQLFSNFEEELIRQGEEAESLSFVYRSLKNLSFTDFIFALQ
                     QEVTTEEEKQFVEDIYQQLAAHKPAQYIIGQADFYGMHLKVDERVLIPRPETEELVEL
                     ILTENLETNLSVLDIGTGSGAIALALAKNRPDWSVTAADVSQEALELASENASDQNLN
                     IFFKKSDCFAEISEKYDIIVSNPPYISREDESEVGLNVLHSEPHLALFADEDGLAIYC
                     RIAEDAKDYLKDGGKIYLEIGYKQGQSVPELFRKHLPEKKVRTLKDQFGQNRMVVVDD
                     GQD"
     gene            complement(8779..9858)
                     /gene="prfA"
                     /locus_tag="VQ543_001002"
     CDS             complement(8779..9858)
                     /gene="prfA"
                     /locus_tag="VQ543_001002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 1"
                     /protein_id="HET2611740.1"
                     /translation="MNIYDQLQAVEDRYEELGELLSDPDVVSDTKRFMELSKEEASNR
                     DTVIAYREYKQVLQNIVDAEEMIKESGGDADLEEMAKQELKDAKAEKEEYEEKLKILL
                     LPKDPNDDKNIILEIRGAAGGDEAALFAGDLLTMYQKYAEAQGWRFEVMEASMNGVGG
                     FKEVVAMVSGQSVYSKLKYESGAHRVQRVPVTESQGRVHTSTATVLVMPEVEEVEYDI
                     DPKDLRVDIYHASGAGGQNVNKVATAVRIVHLPTNIKVEMQEERTQQKNREKAMKIIR
                     ARVADHFAQIAQDEQDAERKSTIGTGDRSERIRTYNFPQNRVTDHRIGLTLQKLDTIL
                     SGKLDEVVDALVLYDQTQKLEELNK"
     gene            complement(9855..10445)
                     /locus_tag="VQ543_001003"
     CDS             complement(9855..10445)
                     /locus_tag="VQ543_001003"
                     /EC_number="2.7.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000068157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidine kinase"
                     /protein_id="HET2611741.1"
                     /translation="MAQLYYRYGTMNSGKTIEILKVAYNYEEQGKGVVIMTSALDTRD
                     GVGYVSSRIGMKRPALAIEETTDIFGYIRGLPEKPYCVLVDEAQFLKRHHVYDLARVV
                     DELDIPVMAFGLKNDFRNELFEGSKYLLLLADKIDEIKTICQYCKKKATMVLRTQDGL
                     PVYDGEQIQIGGNETYISVCRKHYFAPEINKENEEK"
     gene            10568..10750
                     /locus_tag="VQ543_001004"
     CDS             10568..10750
                     /locus_tag="VQ543_001004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005589823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-oxalocrotonate tautomerase"
                     /protein_id="HET2611742.1"
                     /translation="MPFVRIDLFEGRTLEQKKALAKEVTEAVVRNTGAPQSAVHVIIN
                     DMPEGTYFPQGEMRTK"
     gene            10887..12260
                     /gene="mnmE"
                     /locus_tag="VQ543_001005"
     CDS             10887..12260
                     /gene="mnmE"
                     /locus_tag="VQ543_001005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002906470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis GTPase MnmE"
                     /protein_id="HET2611743.1"
                     /translation="MITREFDTIAAISTPLGEGAIGIVRLSGTDSFAIAQKIFKGKDL
                     NKVASHTLNYGHIIDPLTGKVMDEVMVGAMKSPKTFTREDIIEINTHGGIAVTNEILQ
                     LAIREGARLAEPGEFTKRAFLNGRVDLTQAEAVMDIIRAKTDKAMNIAVKQLDGSLSD
                     LINNIRQEILNTLAQVEVNIDYPEYDDVEEATTAVVREKTMEFEQLLTKLLRTARRGK
                     ILREGISTAIIGRPNVGKSSLLNNLLREDKAIVTDIAGTTRDVIEEYVNINGVPLKLI
                     DTAGIRETDDIVEQIGVERSKKALKEANLVLLVLNASEPLTAQDRQLLEISQDTNRII
                     LLNKTDLPETIETSKLPEDVIRISVLKNQNIDKIEERINNLFFENAGLIEQDATYLSN
                     ARHISLIEKAVESLQAVNQGLELGMPVDLLQVDLTRTWEILGEITGDAAPDELITQLF
                     SQFCLGK"
     gene            complement(12307..13242)
                     /gene="dapA"
                     /locus_tag="VQ543_001006"
     CDS             complement(12307..13242)
                     /gene="dapA"
                     /locus_tag="VQ543_001006"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HET2611744.1"
                     /translation="MSYQDLKECKIITAFITPFHEDGSINFDAIPALIEHLLAHHTDG
                     ILLAGTTAESPTLTHDEELELFAAVQKVVNGRVPLIAGVGTNDTRDSIEFVKEVAEFG
                     GFAAGLAIVPYYNKPSQEGMYQHFKTIADASDLPIIIYNIPGRVVVELTPETMLRLAD
                     HPNIIGVKECTSLANMAYLIEHKPEEFLIYTGEDGDAFHAMNLGADGVISVASHTNGD
                     EMHEMFTAIAESDMKKAAAIQRKFIPKVNALFSYPSPAPVKAILNYMGFEAGPTRLPL
                     VPAPEEDAKRIIKVVVDGDYEATKATVTGVLRPDY"
     gene            complement(13298..14374)
                     /locus_tag="VQ543_001007"
     CDS             complement(13298..14374)
                     /locus_tag="VQ543_001007"
                     /EC_number="1.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000542485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate-semialdehyde dehydrogenase"
                     /protein_id="HET2611745.1"
                     /translation="MGYTVAVVGATGAVGAQMIKMLEESTLPIDKIRYLASARSAGKS
                     LKFKDQDITIEETTETAFEGVDIALFSAGSSTSAKYAPYAVKAGVVVVDNTSYFRQNP
                     DVPLVVPEVNAHALDAHNGIIACPNCSTIQMMVALEPVRQKWGLDRIIVSTYQAVSGA
                     GMGAILETQRELREVLNDGVKPCDLHAEILPSGGDKKHYPIAFNALPQIDVFTDNDYT
                     YEEMKMTKETKKIMEDDSIAVSATCVRIPVLSAHSESVYIETKEVAPIEEVKAAIAAF
                     PGAVLEDDVAHQIYPQAINAVGSRDTFVGRIRKDLDAEKGIHMWVVSDNLLKGAAWNS
                     VQIAETLHERGLVRPTAELKFELK"
     gene            complement(14716..14788)
                     /locus_tag="VQ543_001008"
     tRNA            complement(14716..14788)
                     /locus_tag="VQ543_001008"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(14753..14755),aa:Thr,seq:ggt)
     gene            complement(14888..15397)
                     /locus_tag="VQ543_001009"
     CDS             complement(14888..15397)
                     /locus_tag="VQ543_001009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HET2611746.1"
                     /translation="MKKLTIRDIADIAIVAAIYVVLTVTPPLNAISYGAYQFRISEMM
                     NFMAFYNPKYIIGVTIGCMIANFFSFGLLDVFVGGGSTLVFLSLGVWLFAKYSKDYLF
                     NGLIRKDHFFFSILFSISMFTIAAELNIVAELPFFLTWFTTGIGEFASLIIGAIIIGK
                     IGRRIDLSK"
     regulatory      complement(15395..15491)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01054"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="PreQ1 riboswitch class II; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF01054"
     gene            15520..15951
                     /locus_tag="VQ543_001010"
     CDS             15520..15951
                     /locus_tag="VQ543_001010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GtrA family protein"
                     /protein_id="HET2611747.1"
                     /translation="MKIPIQKFFNNEILAYLFFGLATTLVSILSRLVIYQLSHQELLA
                     TALANIIGILFAFITNDTIVFKQKKKNRLIRLVKFSLARLSTFLLDLFLTFLFVTQFP
                     HIIGQFVTENIDKINAIETIIAQIFIIIINYILSKAYIFRK"
     gene            16033..16410
                     /gene="mscL"
                     /locus_tag="VQ543_001011"
     CDS             16033..16410
                     /gene="mscL"
                     /locus_tag="VQ543_001011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="large conductance mechanosensitive channel
                     protein MscL"
                     /protein_id="HET2611748.1"
                     /translation="MLKNLKSFLLRGNVIDLAVGVVIASAFGAIVTSLVNDIITPLIL
                     NPALKAAKVERIAQLSWHGVGYGNFLSAIINFIFVGTALFFIIKGIEKAQKLTGIKKE
                     KTAEKKPTELEVLQEIKALLEKK"
     gene            complement(16452..17546)
                     /gene="hemH"
                     /locus_tag="VQ543_001012"
     CDS             complement(16452..17546)
                     /gene="hemH"
                     /locus_tag="VQ543_001012"
                     /EC_number="4.98.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrochelatase"
                     /protein_id="HET2611749.1"
                     /translation="MKKAILMMTFGSPEEISFEGVAEFFTNIRRGVRPQDHEIQTLYD
                     NYIRIGGTPLQRITREEVNLVKERLGEEYGIYFANKFSRPFIPDVIKQMETDGVEECI
                     CLILEPHYSFYSVMGYEKFLESKQIQFLVIKDWYQEEVLLNYWADEIAKILKEEVKQD
                     SFKVIFSAHSVPIFALDFGDPYIDQIFENSKLVAEKLGLSSEQYTNTWQSESDIGIPW
                     IKPDVLEYLREQTEHPDHYIFVPISFISEHIEVLFDNDVECYDLCQEFGVNYHRPPMP
                     NTDSRLIDALVNTVRVNENQEFKEFLPEEETFDELVPSDETKNILAESEDLQMPEFVK
                     KLIEKKGRENVKMPYLIKKMLEKAGKLPKE"
     gene            complement(17624..18456)
                     /gene="srtG2"
                     /locus_tag="VQ543_001013"
                     /pseudo
     CDS             complement(17624..18456)
                     /gene="srtG2"
                     /locus_tag="VQ543_001013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000218039.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PI-2 pilus system class B sortase SrtG2"
     gene            complement(18534..19532)
                     /gene="srtG1"
                     /locus_tag="VQ543_001014"
     CDS             complement(18534..19532)
                     /gene="srtG1"
                     /locus_tag="VQ543_001014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000851047.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PI-2 pilus system class B sortase SrtG1"
                     /protein_id="HET2611750.1"
                     /translation="MKTKREKPKKSLSRRLVLAVDGVINHLLLIFAALIFLFGFYALW
                     DSNQVYSLASSSEYEAYRPVTTQQDELASFSGFSKLQELNPEVLGWINVYGTNIDYPL
                     VQAKDNEKYLNKDSKGEFAATGAIFLDARNNPKFEDFNTIIYGHHVENGVMFGDVAKF
                     ADQEFFDQHRYGSIYYNGVEKGLEIFEMLEVDAYDFNIYDPGIQGEDRQQAYLDHLLS
                     VAMHKRDISLSPSDRIILLSTCFLDVTNGRHIVVAKITDTVPKNTFHTKKSKPFPYSV
                     FDDSSLGRFLSSIPLWIWYLILFVLFLLLIFLLLVLYLILRRRRESKKNARSRPFY"
     gene            complement(19550..20746)
                     /gene="pitB"
                     /locus_tag="VQ543_001015"
     CDS             complement(19550..20746)
                     /gene="pitB"
                     /locus_tag="VQ543_001015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000750612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PI-2 pilus major pilin PitB"
                     /protein_id="HET2611751.1"
                     /translation="MKKTFFKKLFTASIAAITALSVFRGVPTFADDNSAITKANGENN
                     AVVKINKTLNIAEGITTPTATFTFKFTEKTGQSSNGAPYQTGVAIPDRNVEYNKNDHP
                     TADKIQKATEDIFSGVAYGHAGEYVYDVAEAKTGWQAITKNGKTIDAMRYDKRTYEMH
                     VIVKNKVNGGVYISSVYFKENNKSNAPKVEPSEQGVYNLFDNTYTKDASKEPNPDDPS
                     QVDPNAKALTITKKVDGASGDKTRDFQFHIKIQLPSTNKTAETPVTNIIVKHGSKSEV
                     LAVVTPADTVEYNFTLKDGETFTVEQLPAGSKYTVTETGVAGYTDSSIYTTNGAEQTS
                     QGQKNVDFTLTDILIGEKKNDNKVTNKIDDVTPTGLLIDNLPFILMIGLGLAGFVVLS
                     KKRREA"
     gene            complement(20791..21342)
                     /gene="sipA"
                     /locus_tag="VQ543_001016"
     CDS             complement(20791..21342)
                     /gene="sipA"
                     /locus_tag="VQ543_001016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000924780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PI-2 pilus system signal peptidase SipA"
                     /protein_id="HET2611752.1"
                     /translation="MLLKKKHKKPVTQVNRDKSPPSVWGDILYLVSKLLMVGFVLAIL
                     YFFVFGLLRYNDDGMKPALKDGDLVVYYRLDKRYSIGDLLVYSYKGKERVARVIATEG
                     STIDINENGLIINGSPQQEQDIYKETLLYKEGATFPMKVPAGQLFVLGDNRTTAVDSR
                     AFGTIPIQDTQGKVVTVIRRRGF"
     gene            complement(21342..23105)
                     /locus_tag="VQ543_001017"
     CDS             complement(21342..23105)
                     /locus_tag="VQ543_001017"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2611753.1"
                     /translation="MIDTPYWFTSGLERGMLNISSLIAPKIDGFYSIKFRYYIGSNDS
                     ITSLKGYISGYNSGIPNEIFSANNENDLQQKFKEITDKILPLGVHHVTISDVLSKYVQ
                     LLPGDASHLRVVKIKDGNEQELNDNQVTIETKKNEQGLVEVTAKFNPSYTLEDDAKYV
                     LKFTVTSSQEAFDAIAGDKTLTSDDAEEADATKLYSNKGAKVAYSYGIGTSRTKIKDY
                     SEKPTFKPSDPLTVPVEIEWKGVDGKSNPSANRPPSVELNLNQKKDGSIKDSYRKVTS
                     PVQTNSFTENTSFAKVAKGYDYELKAPDAPGYTVEVQKTGTKEKPSFKVIYRQLPSLT
                     VKKILEGEQSPNKSFTINVTFSDKDGKPINGKFGNTTVTNGKAQISLKNSQETALSYL
                     PRDTHYKVEEVENSRTGYHVTYEKQEGTLSEDVQTIVTNHRLPTLSVTKKVTGAFANL
                     LQSFKITINVKDAQNKPLNGSYSAIVNNQKTTLQFTNGKATVDLKKDKTIKILDLPLN
                     ARYSIEEEASSSRGYQVSYDKKEGTLDANKSATVTNNKNSVPETGIDFLSSTLVLGVV
                     LPLGGIFFIILLGHLVVNRRK"
     gene            complement(23427..23930)
                     /locus_tag="VQ543_001018"
     CDS             complement(23427..23930)
                     /locus_tag="VQ543_001018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001102795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adhesin"
                     /protein_id="HET2611754.1"
                     /translation="MNVQYDFKKIQYFTSSLVIFLAILFLCAPINSLRADSITEPQTT
                     LHKTITPISGQKDQYELSLDITSKLGTETQSEPLDVVLVADLSGSMEERDVWSYSSRR
                     YISRIEALKHTLKGVNGRQGLIDTILSNSQNRLSIVGFAGKIDNQYNDRYYNEYYLSY
                     QYGTWPN"
     gene            24289..25512
                     /gene="pepT"
                     /locus_tag="VQ543_001019"
     CDS             24289..25512
                     /gene="pepT"
                     /locus_tag="VQ543_001019"
                     /EC_number="3.4.11.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000222045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase T"
                     /protein_id="HET2611755.1"
                     /translation="MTYPNLLDRFLTYVKVNTRSDEHSTTTPSTQSQVDFATNVLIPE
                     MKRVGLQNVYYLPNGFAIGTLPANDPSLTRKIGFISHMDTADFNAEGVNPQVIENYDG
                     GVIELGNSGFKLDPADFKSLEKYPRQTLITTDGTTLLGADDKSGIAEIMTAIEYLTAH
                     PEIKHCEIRVGFGPDEEIGVGANKFDAEDFDVDFAYTVDGGPLGELQYETFSAAGAEL
                     HFQGRNVHPGTAKGQMVNALQLAIDFHNQLPENDRPELTEGYQGFYHLMDVTGSVEEV
                     RASYIIRDFEKDAFEARKASMQSIADKMNEELGSDRVTLNLTDQYYNMKEVIEKDMTP
                     ITIAKAVMEDLGITPIIEPIRGGTDGSKISFMGIPTPNIFAGGENMHGRFEYVSLQTM
                     ERAVDTIIGIVAYKG"
     gene            complement(25548..26177)
                     /locus_tag="VQ543_001020"
     CDS             complement(25548..26177)
                     /locus_tag="VQ543_001020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000030436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2611756.1"
                     /translation="MNKANQLLEQIHEEGIRQSLAEEVENLKAATNKADADLDEVNSQ
                     VKDVLTRIASALQQEKENAEQDSQTLVLYQKLYDILMSLHSYLESNNGSDADFDKVDA
                     LLDQLSANSKDKTALLESTKAILVLNHQIQSKVSASEETSPARNAEANSDNTSAENQP
                     NATAESNIETASDENKPSNTRDSKPAESTSENETTESSTTTGNQEKPVE"
     gene            26142..26363
                     /locus_tag="VQ543_001021"
     CDS             26142..26363
                     /locus_tag="VQ543_001021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2611757.1"
                     /translation="MDLFQELICLVQKTFYFFLAICRRLLVAIYHVLLKQESYNPRLQ
                     GLTEIRNPDKTMFVQDAIRFAQQHGFNML"
     gene            complement(26634..26982)
                     /locus_tag="VQ543_001022"
                     /pseudo
     CDS             complement(26634..26982)
                     /locus_tag="VQ543_001022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669441.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
     gene            complement(27087..27647)
                     /locus_tag="VQ543_001023"
                     /pseudo
     CDS             complement(27087..27647)
                     /locus_tag="VQ543_001023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669441.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
     gene            complement(27873..30992)
                     /gene="phtE"
                     /locus_tag="VQ543_001024"
     CDS             complement(27873..30992)
                     /gene="phtE"
                     /locus_tag="VQ543_001024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000672589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtE"
                     /protein_id="HET2611758.1"
                     /translation="MKFSKKYIAAGSAVIVSLSLCAYALNQHRSQENKDNNRVSYVDG
                     SQSSQKSENLTPDQISQKEGIQAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDALFSE
                     ELLMKDPNYQLKDADIVNEVKGGYIIKVDGKYYVYLKDAAHADNVRTKDEINRQKQEH
                     VKDNEKVNSNVAVARSQGRYTTNDGYVFNPADIIEDTGNAYIVPHGGHYHYIPKSDLS
                     ASELAAAKAHLAGKNMQPSQLSYSSTASDNNTQSVAKGSTSKPANKSENLQSLLKELY
                     DSPSAQRYSESDGLVFDPAKIISRTPNGVAIPHGDHYHFIPYSKLSALEEKIARMVPI
                     SGTGSTVSTNAKPNEVVSSLGSLSSNPSSLTTSKELSSASDGYIFNPKDIVEETATAY
                     IVRHGDHFHYIPKSNQIGQPTLPNNSLATPSPSLPINPGTSHEKHEEDGYGFDANRII
                     AEDESGFVMSHGDHNHYFFKKDLTEEQIKAAQKHLEEVKTSHNGLDSLSSHEQDYPSN
                     AKEMKDLDKKIEEKIAGIMKQYGVKRESIVVNKEKNAIIYPHGDHHHADPIDEHKPVG
                     IGHSHSNYELFKPEEGVAKKEGNKVYTGEELTNVVNLLKNSTFNNQNFTLANGQKRVS
                     FSFPPELEKKLGINMLVKLITPDGKVLEKVSGKVFGEGVGNIANFELDQPYLPGQTFK
                     YTIASKDYPEVSYDGTFTVPTSLAYKMASQTIFYPFHAGDTYLRVNPQFAVPKGTDAL
                     VRVFDEFHGNAYLENNYKVGEIKLPIPKLNQGTTRTAGNKIPVTFMANAYLDNQSTYI
                     VEVPILEKENQTDKPSILPQFKRNKAQENSKLDEKVEEPKTSEKVEKEKLSETGNSTS
                     NSTLEEVPTVDPVQEKVAKFAESYGMKLENVLFNMDGTIELYLPSGEVIKKNMADFTG
                     EAPQGNGENKPSENGKVSTGTVENQPTENKPADSLPEAPNEKPVKPENSTDNGMLNPE
                     GNVGSDPMLDPALEEAPAVDPVQEKLEKFTASYGLGLDSVIFNMDGTIELRLPSGEVI
                     KKNLSDLIA"
BASE COUNT         8835 a         6360 c         5686 g        10121 t
ORIGIN      
        1 aaaaggatct agtttttatt tttagttaaa ttatgtctat atttttcatt aactcatcaa
       61 taaaaatttg tttgctaata tctctttctt ctgattttgt ttcaaggatt attgctacat
      121 cattcatatt tttaggtaaa taccaaccat ctggcttatc tgaatatccc ttgaagccta
      181 attgattaaa agtagttatt tgaccagtac cttgattgat gttttcttca acttcattaa
      241 agcctatact tctcttgcat aatccctaac ttgatcttct gtccttaaag tcattttcta
      301 ttcctcgtca ctaaaattat cttcaaaact aataatatca ttaggagtgc aagataaagc
      361 cttacatatt ctttctaaat tcttaaatgt aattggttta tcctttccca tttgtgccat
      421 aacatttgtt gtaagtcctg ccatagctat tacatctgtt ttctttagtc ctttttttgc
      481 taactgtatc cataatggtt tatagttaag taccataata tccctctttt tttcttcatt
      541 aaatttattt aattatagca taaatattga tttcattcaa tcttacattg atttagtgat
      601 ttgttttaga gaatttgttg tgttattccg tccttatttt gccataaatt gttttaagtg
      661 ggacctctta tccttaccat ttttacctcc taattttgag tataaaaaag acgatagagt
      721 ttttaatttc tatcgtctga gatttacata ttaaattttc atcacaaaat aagactcttt
      781 aaagaatctt taaattcatt ggtatgctgc ttacaatatc cattattaaa atggatacta
      841 taagcagcac accaactatt tattttttga gttttaaact ttggtagaag tcttgaactc
      901 cttatattta cataactatt tgcctctata actattatga cacgaaacca acaagcaagt
      961 tcaagcatct ccatatcttt attcaaatga ggactaagat attcacaaac tttatcataa
     1021 acctctttat cttttttcat aaaaggggca tacaacttag caaatttatc ctaaaatttt
     1081 ttgttgcctt tatcaatcat ttcaacgctc ctttaaatat aaaaataatc ctatcaatct
     1141 ttatattgag cctattttct aattgatacc ttgcaagaaa ggaataatag ctgttcctat
     1201 accaagtagg aatgtaataa atgcagaaag tcatatactg tcattctttt ctattaaatc
     1261 attttgaagt gtctcaaagc atccatgatg gcttcttctt tttcaggtgt acactgtgga
     1321 ataatttgtt tatccttttt agacttgttg taatgttctc gtaattctat tccacatttc
     1381 ttttttatct gtgcaatata taatgtcgaa acttttaatt caaatttatt ccaaacatat
     1441 tctttgattt gagcatatgt tgctttgctc tccgcacttg tcaaatccat ctcatccagc
     1501 tcaatttcaa cacttatgtg cttatcgaca tcgagtttgg acaaaagtgc taccgtctcg
     1561 acgtgatgcg tttgaggaaa tagatccacc ggctggactt tcttcaattc atatcccaat
     1621 tcttggtaga gtttgatatc acgcgccatg gttgcgacat tgcaggagat ataggcgatg
     1681 cgatcggctc ctgtttgggc gcttgctttg ataaagcttt ctgtcaagcc cttgcgtgga
     1741 ggatcaacca agataacggt tggttgaata ccttccttga gccatttctt catggcattt
     1801 tcagccgtgt cacagacata gtgggcatta gtaatcttgt tcaaagaagc attcttctgg
     1861 ctattctcaa ccgcttctgg aatcagttca acaccgtaga cttctttgac atgcttggcg
     1921 actgataaac caatggttcc aataccagaa taagcatcaa taaccacgtc atcttttttt
     1981 aactctgcaa agtcaatggc tgtttgatag agtttctccg ccatttcagt attgacttgg
     2041 taaaaggctg ggccagcgat ttggaagtca tttcccaaca tctggtccgt aatatagtct
     2101 tgaccataaa gagtgcacca ctccttacca aaaatcgcat tggtattctg gtcgttgata
     2161 ttttgcatga cagacacaat ctctgggaac tgcttgataa cttgttcaat caattggtca
     2221 acacgaaaaa cttttggacg agttgtcacc aaaacgacca tgatttgtcc tgaatagtga
     2281 ccacgacgca ccacaagatt ccgaatcaat ccagactgtt ccttttcgtc ataaggtttt
     2341 aaatcaaaac gacggagcag gtctcgaaga gctactacga cttggtcaat gacaggatcc
     2401 tggataaaga aatcttcaag gggcatgagg ttgtgcgaat tcttacggaa aaatcctgtt
     2461 tccaagacac cattcactcg acgaacgggc acctgcgcct tattgcgata cttgactgga
     2521 tgttccatac caagcgtttc agcaacttct acatctgcaa ttccagcaat cttgtagaga
     2581 ctgtccttga cttgcttggt tttaaacttg agctgttctg gataagaaag gtgtcctaaa
     2641 tccgcgattc ctgaacgcag gtaagccaaa tctagatctt gattacggtg tagtgactgg
     2701 acaaggtatt tttcaacttt tccaaagcca atctttttat tgaccttgag gacacgcatg
     2761 agaatttttt cactcggtaa agcattctct acaaaaaaga ccaaaccatc taccttggca
     2821 actcctgccc cttcatgggt caaatcaaca atttcaactt ctacaatatc atttttcttt
     2881 aacattcttt tctctttcta ttggccgaca aaaaagacgg caacgttacg attaccatcc
     2941 attataccat gaaatttctt aagaaccaaa actcttgaag aagttgacaa gggcttgcca
     3001 gagggagctt aagaagttac caccgtcctc tagcgcctta tccgcatcaa agttaaggtt
     3061 gatattttta aaactgtcgc cagcttgtga tacgatgctt tgtttaaggt catttagggt
     3121 tttagtgaaa tctgcattgc tgaggatatc actctttgag agattcaagg caaaattgat
     3181 gatgatattg atctggtttc ctgttatgac ctgatcaagt ttgtaatttt ttaaggtatc
     3241 ttcaacaatc ttgcggacat cttcttctgt cagatttccc ttgctttctt tagctttggc
     3301 gagtcctgac ttgatatcag ctagggcaac gtttaattta ttagcatcat agcctgattt
     3361 gtccttgttt tcagcattga tatctgacaa agcctttagc tcttcttgag ccaaatcttt
     3421 attggcttgc ggcaccttgg ctccattagc ttctagcgaa tagtagatcc cagccaaagc
     3481 actctcacct gtaactggaa taggggctgc tacagtgatt ttggcatgtt ccatacccag
     3541 cgttactgct gcgtttcggt acatatcctg agtcacctta gtgatatttt ctggtgtttc
     3601 aatcttgacc tcaagtggcg atttgtcacc tagcttttga atcttggctg atgaatacaa
     3661 ctgtaagcta gagtcattgg ccacattcat gattttagaa taaacatcag gtgtcatggt
     3721 cttgagttct ttggtatctg ttgaggcatt gtagcccagt tttttaagag tttgattttt
     3781 ttggtcttca gatagggagg aacctaggac atattcaggt tggacatagg tttcatcgat
     3841 aaccttttga acatctgttg ctgcatggac gctattcata gctgttactg cccacaagac
     3901 cgcagcactg gtcagaaaga gtttctttct catagggaat ttcctccttt acttttctag
     3961 agtaatatat ctatcttaaa gaaaacttat aacaaaaaca cctggtctag ccagatgttg
     4021 aaaagagagt gaaacatttg atgatgtaaa ggttaagtcg tacctgtcta gaataataat
     4081 agtttcctcc atttacatag agttcagcac cgtgaaaaat ggaaatgggg tgaatataac
     4141 tataagtctt tccagtcgta ttaccaagca agggggcaac agtctcacga gagtactgtt
     4201 tggctagagc caaggtattt tccttgccat tttgggcgat aaaatcgata taggcaggtc
     4261 caaaattata ggcttgaaca gctgtccaga tatctacccc cttcttctgc gccagataga
     4321 gattgcctgt cagagtttga atgccttgcc gaatgctaga ggcattatca ttgatggtgt
     4381 tggttgaacc acttgcagac tcactagact gcataacatc gccttctttt ccttttgttt
     4441 cagtataaat catagcaagc acaagctctt cgtttgctgg ggtgtctttt tcactcaaga
     4501 tttctcgcac catgggttga taggtcatga cttgtttgac atcttgatga acgcggtaag
     4561 ctttatagcc agcaaaaagg aagactgcta gtacaagcac tcttcgaatt cgtttaaaca
     4621 ttatttactt tggatatcct cgatattttt gattaagata gagtaggttc cattttcctt
     4681 ttggataaac tcaacagact cggcgtcttg atagacgtta ttgggaacga tgagctcaat
     4741 tccatttgat aaggagagtt tttggttttc aaatttcttt aattggcgac tggcatcaat
     4801 ttcatcaaat tgaacaggtt ctggtacggc ttctttgact tggtcaataa agctcaaacg
     4861 agccgtcaga ttgttgtcaa aaaggtcatt agccaatttc tcaggtgaca attcattgct
     4921 ttcttctagg ttgttgaaaa tcgctgattt gaccttggat tgaaattgaa aatcatctgt
     4981 gttaaaagat tcagcaattc tctgggctgt tttttccagt tccttgatag attttttagg
     5041 agaaatctta ggagcgacag caagaagatt atctgaaaaa tagttcaaaa aagtcccgtt
     5101 gtacttgatt cgtttttcaa tcaggtgata cttgcgactc tgaagattga ccaccaaggc
     5161 ctcgtcagca cccgttccaa atccaggcag gttattctga gtcagcttga ttggattatc
     5221 aacttctcct ccgaggtggg tcaaggtctc ccgcagggca attcgcaaga aagcgaaatg
     5281 ttctacacct tctttagaaa attgaacaaa aatcaagtca ttggtcttga gattttcaga
     5341 aatgctaaac tcctctttcc agagattagc cagcgttact gatgtctcca acaaatcgtc
     5401 tgtaatatga ttgaagaagg gattttcttc ttcgaaaatc ccagtcttgg cttcatctga
     5461 atacacatgt tcaatttttt tacgtaggta ttcttcgatt tttggagtaa tattgagaaa
     5521 cttatctgct aagaacagct cggtatcatc cggactgaac tggtgaataa tggctttctt
     5581 aatataaatg tccataaaag ttttattcct cgtataatgg gaaggcatct gtcaattctt
     5641 tgactgcact tctcacttct tctaatacag cctcattttc tgaattctta agggttttaa
     5701 tgatgagttc agccactttg cgactttctt cttcaccaaa tccacgtgca gtaatagctg
     5761 ctgctccgat acgaatccca cttgtcttga atggtgacaa ggtttcgtaa gggattgaat
     5821 ttttatttag ggtaatattg acttcatcca gcaagttttg agcaactttt ccgttttcta
     5881 caaccttagt cacatcaaca aggaagagat ggttttcagt tccacctgaa ataatacgga
     5941 aatcagggtc ttgcaagaag acatctgcca tagccttgct gttcttaatt acattggcag
     6001 catattcctt gaaggctgga tccaaaactt ctttgaagga aactgcctta gccgccacaa
     6061 catgctctaa aggaccgccc tgaatacctg ggaaaatagc tgaattgatt tttttagcaa
     6121 gttcttcgtc attggtcaaa atcaaaccac cacgaggtcc acgaagggtt ttgtgggtcg
     6181 ttgttgtagt gatatgagcg tatggcactg ggcttgggtg aagaccagct gcaaccaagc
     6241 cagcgatgtg ggccatatca accataagct tcgcaccgac agcatctgcg atttcacgga
     6301 attttgaaaa gtcaataatt tgagaatagg ctgaagcacc agctacaatc agttttggtt
     6361 ttacttcttg ggcttgtttc aagatagcat caaagtctaa gagttccgtt tcaggatcaa
     6421 cactataaga aacaaagttg taggtttgac cagagaagct aacaggagcc ccatgagtca
     6481 aatgaccacc tgatgccaaa tccattccca taaccgtatc acctggctca atcaaggaca
     6541 tgtaagccgc acagttggcc tgacttcctg agtgaggttg gacattggca aatttagcac
     6601 cgaaaatttc ttttgcgcgt tcaatagcaa gagtctctac aacgtctact acatcagttc
     6661 caccataata acggcgtcct gggtaaccct cggcatattt atttgtcaag atagaccctt
     6721 gagctgccat aacagccttg gaaactacgt tttccgaagc aattaactcg atattatttt
     6781 gttggcgttc ttcttctttg gcaatagcat tccagagatc agcatcatat gctttaaaat
     6841 catctttgtc aaaaatcata ggtcttctcc tttattgtgt gactagtcca ttagtttgat
     6901 tttacaataa gaaaatcaaa ctaaaagatg cgaataaacc gtttctgcat tttatcacaa
     6961 gtatagccaa ctttttcata aaatgcatga gcacccagac gatgattggc agaatttaag
     7021 cggataaacc cataaccaca tcttttggct tcttgttcca acccttgtag taaactttta
     7081 ccgatacctt gaccttgcgc ttgaggtgaa actgctaaag ctaagatatt aaatcctgct
     7141 ttggaataga gtgattcgta aacttcagcg tggacatatc caagtaagac atgattagct
     7201 gcatcctcat agccaagtag gaaatgatgg gaatcctgag acagtctagc tagttggcta
     7261 gccgtttcct ctggactaaa agtataaccc aaagcctctt ggttgatgtc acatatcgct
     7321 ttcacatctg tttcttgcaa atctcttagc atttcaagcc tcctcaaaag aaatctctgg
     7381 caaccgagca agaatatctt ctcgtttaat tgcgccttgg cgtaagattt tcaccttgtc
     7441 tccagacaaa tccacaatag ttgaatcctg tccagttaga aaagcatcgt cttccagacc
     7501 cagaacctct tggtcaaaat ccttcagaat ttgttcaaag gttacaccac ttgcctgacc
     7561 tgagatattg gcagacggcc caatcaaggg acctgtctct cgaattaaat ccagtgtgat
     7621 agggtgactg ggcatccgaa atccaatagt tgcaaggtca gaatttaccc aatagggaac
     7681 tcggtcattg gcttcgagaa taatggtcaa gggacctggc aaaaaggtct ctacaagttt
     7741 ttgtagataa gttggctgat tcttagaaaa gtgcaagata tcctcgaaag aggcgatatt
     7801 gagattgagt gccttatctc taggacgacg tttgagttgg taaacatggt caactgcttt
     7861 ttcatctaag gccttggcaa aaagaccata aacagtctct gtaggtagaa cgacagctcc
     7921 accattttcc aactcttgtc taatcctgtc catcatcaac cacaaccatc ctattttgac
     7981 caaattggtc tttgagtgtt cgaacttttt tttcaggaag atgttttcta aaaagttcgg
     8041 gaacactttg accttgcttg tatccaattt caaggtaaat cttaccacca tccttgagat
     8101 agtcttttgc atcttccgca attctacagt aaatagctag gccatcctcg tctgcaaaga
     8161 gagctagatg aggctccgaa tgcaaaacat tcaagcctac ctctgactca tcttcacgag
     8221 agatataggg tggattggat acaattatat catatttttc agaaatttct gcaaaacaat
     8281 cagatttttt aaaaaatata ttaagatttt gatcgctagc attctctgat gcaagctcta
     8341 aggcctcttg agaaacatct gctgctgtca ctgaccaatc tggtctattt tttgctagag
     8401 cgagagcaat agctccacta cctgttccaa tatccagaac tgagagattc gtctcaagat
     8461 tttcagttag aataagctcc actaactcct ctgtttctgg acgaggaatc aaaacccgtt
     8521 catccacctt taaatgcatt ccataaaaat ctgcctgtcc aatgatgtac tgagctggct
     8581 tgtgagctgc tagttgctgg taaatatctt ctacaaattg tttttcttcc tctgttgtca
     8641 cctcctgctg gagggcaaaa ataaagtctg taaaagatag atttttcaga ctacgataga
     8701 caaaagagag gctttccgct tcctctcctt gtcttatcaa ctcttcttca aaatttgaaa
     8761 ataattgagc taatttcatt atttgtttaa ttcttctagt ttttgtgttt ggtcataaag
     8821 caccaaggca tccacaactt cgtccaattt accagacaaa atcgtatcta gtttttggag
     8881 ggtcaagccg atacggtggt ctgtgacacg gttttgaggg aagttataag ttcggatccg
     8941 ttctgaacgg tcaccagtac cgattgtcga cttacgctca gcgtcttgtt catcctgagc
     9001 aatctgagca aagtggtcag cgacgcgtgc acggataatc ttcatagcct tctcacggtt
     9061 cttctgctgg gtacgttctt cctgcatctc aaccttgata ttggttggca agtgaacgat
     9121 acgaacggca gtcgcaacct tattgacgtt ctgtccacca gcacctgatg cgtggtaaat
     9181 atcaacacga agatcttttg gatcgatatc gtattctact tcttcgactt caggcatgac
     9241 aagaactgtg gcagttgagg tatgaacacg accttggctt tctgtcacgg ggacacgctg
     9301 cacacggtgg gcacctgatt cgtacttaag cttagagtat acagactgac ctgaaaccat
     9361 agcaaccact tctttaaacc caccgacacc attcatagag gcttccatga cttcaaagcg
     9421 ccagccttgg gcttccgcat acttttggta catagttagc aaatctccag cgaaaagtgc
     9481 cgcttcgtct ccaccagctg ctccacggat ttcaaggatg atattcttgt catcgtttgg
     9541 atcctttgga aggagcaaaa ttttcagttt ttcttcatat tcttcttttt cagccttggc
     9601 atctttgagt tcttgcttgg ccatttcttc caagtccgca tctccgcctg attccttaat
     9661 catctcttcg gcatcgacga tattttgaag gacttgttta tactcacggt aggctattac
     9721 ggtatcacga ttggaagctt cttcttttga aagctccata aaacgcttgg tgtctgaaac
     9781 gacatcaggg tcactcagca attctcctag ttcttcataa cggtcttcta cagcttgtag
     9841 ttgatcatag atgttcattt ttcttcattc tccttattga tttcaggggc aaaataatgt
     9901 ttacggcaaa ccgagatata ggtttcatta ccaccaattt ggatctgttc tccatcgtaa
     9961 acgggcagtc catcctgtgt tcgcaacacc atggtcgcct ttttcttgca atactgacag
    10021 atggtcttga tttcgtcaat cttgtctgct aaaagcaaga gatatttgga accttcgaac
    10081 aattcattgc gaaagtcatt tttcaagcca aaagccatga cgggtatgtc taactcgtcc
    10141 acaacacgag ctaggtcata aacatggtgg cgtttgagaa actgggcttc atcgaccaac
    10201 acacagtaag gtttttctgg taggcctcgg atatagccaa agatatccgt tgtttcctca
    10261 atcgcaaggg cagggcgttt catgccaatt cgactcgaca catagccaac accgtcacgc
    10321 gtatccagag ctgaagtcat aatcacaaca ccttttcctt gctcctcata gttataggcc
    10381 accttgagaa tctcgattgt ctttccagag ttcatggtcc cataacgata atacaactgt
    10441 gccatgtttc ttgcttcacg tccatttcta aatttttgct acattctagt atatcataat
    10501 tttcttaagc tttaaacggc aaaatgtggt aaaatggaag aaatcaaaac tagtggagga
    10561 agctattatg ccatttgtac gcatcgattt atttgaagga cgcacgctcg agcaaaagaa
    10621 agctcttgct aaggaagtaa cggaagcagt tgtccgcaac actggagccc ctcaatctgc
    10681 tgtccatgtc atcatcaacg acatgccaga aggaacttac ttcccacaag gggaaatgcg
    10741 tactaaataa gctagcttaa gcagaattgc ttaggctttt tcaatctcca agtagcattc
    10801 attgaagaaa tatcctaaat ttgttacaat ttgaaaagaa acttggagaa tttccaagaa
    10861 aagagctatt aattaaagga aacattatga ttacacgtga atttgatacc atcgctgcta
    10921 tctctactcc actaggtgaa ggggctattg gtattgtccg cctgagcgga acagacagtt
    10981 ttgctattgc gcaaaagatt tttaaaggaa aagacttgaa caaggttgcc agccacactc
    11041 tcaactacgg tcacattatt gatcctctga ctggtaaagt catggacgag gttatggttg
    11101 gggctatgaa gtctccaaag accttcactc gtgaggatat tatcgagatt aacacccacg
    11161 gtggtattgc ggtgaccaat gagattctcc agctagctat ccgtgaagga gctcggttgg
    11221 cagaacctgg tgaatttacc aaacgtgcct ttttaaacgg tcgcgtagat ttgacacagg
    11281 ccgaggcggt gatggatatc atccgcgcca agacagacaa ggccatgaac atcgcggtca
    11341 aacaacttga tggttccctt tctgatctta tcaataatat ccgtcaagaa atccttaaca
    11401 cacttgccca agttgaggtc aatatcgact atcctgagta tgacgatgtt gaggaagcca
    11461 ctactgctgt tgtccgagag aagacaatgg agtttgagca attactaacc aagctcctta
    11521 ggacagcacg tcgtggtaaa atccttcgtg aaggaatttc aacggctatc attggacgtc
    11581 ccaacgttgg gaaatcaagc cttctcaaca acctcttgcg tgaggacaag gctatcgtaa
    11641 ccgatatcgc tgggacaaca cgagatgtca tcgaagagta cgtcaacatc aatggtgtac
    11701 ctctcaaatt gattgataca gctggtattc gtgaaacgga tgatatagtg gaacaaatcg
    11761 gtgttgagcg ttcgaaaaaa gccctcaagg aagccaactt ggttctacta gtgctaaatg
    11821 ccagtgaacc actgactgcg caagacagac aacttcttga aattagccaa gataccaatc
    11881 gcattattct acttaataaa accgacctgc cagaaacgat tgaaacttcg aaactacctg
    11941 aagacgttat ccgtatttca gtccttaaaa accaaaacat cgacaagatt gaagagcgaa
    12001 tcaacaacct cttctttgaa aatgctggct tgattgagca agatgctact tacttgtcaa
    12061 acgcccgtca catttccctg attgaaaaag cagttgaaag cctacaagcc gttaatcaag
    12121 gtcttgagct ggggatgcca gttgatttgc ttcaagttga cttgactcgt acttgggaaa
    12181 tcctcggaga aatcactggg gatgctgctc cagatgaact catcacccaa ctctttagcc
    12241 aattctgttt aggaaaataa gaaaaatcca tgatccttca ttcggtcatg gattttattg
    12301 tctttattag taatctggtc ttaagacccc tgttacagtt gccttagttg cttcgtagtc
    12361 gccatctacg acaaccttga taatgcgttt ggcatcttct tctggtgctg gaacaagagg
    12421 tagacgagtg ggtccagctt caaatcccat atagttaaga attgccttaa ctggagcagg
    12481 acttggataa gagaagagag cattaacctt aggaatgaat ttacgctgaa ttgctgcggc
    12541 tttcttcata tcgctttctg caatggcagt aaacatctcg tgcatttcat ccccatttgt
    12601 atgagaggca acagaaataa ccccatccgc cccaaggttc atggcatgga aagcatctcc
    12661 atcctcacct gtataaatca agaactcttc aggcttgtgc tcaatcaagt aagccatatt
    12721 agccaagcta gtacattctt tgacaccgat aatatttgga tggtcagcca agcgaagcat
    12781 ggtttctgga gtcaattcga caactacacg ccctggaatg ttatagataa taattggtag
    12841 gtcagaagca tctgcaatag tcttaaagtg ctgatacatc ccttcttgag aaggtttgtt
    12901 gtagtaagga acaatagcaa gcccagctgc gaaaccacca aattccgcta cttctttgac
    12961 aaactcaata gagtcacgcg tatcattagt acctacaccc gcaatcaaag gaacgcgtcc
    13021 attgacaacc ttttgtacag ccgcaaacaa ctccaactcc tcatcgtggg tcaaagttgg
    13081 actctcagca gtcgttcctg cgagaagaat tccatccgta tgatgggcca ataaatgctc
    13141 aatcaaggct ggaatagcat caaagttaat agaaccatcc tcatgaaagg gggtaataaa
    13201 ggctgtaatg attttacatt cttttaaatc ttgataagac atgaaaacac ctctctattt
    13261 caaagaagga gttcatctga actcctaaac gatatgacta ttttaattca aatttcaatt
    13321 cggctgttgg acgaaccaat ccacgttcat gaagagtttc agcaatctga actgagttcc
    13381 aagcagcacc tttgagaagg ttatctgaaa caacccacat gtgaattcct ttttctgcat
    13441 ccaagtcttt acggatacga ccaacaaagg tatcacgcga accaactgca ttgatagctt
    13501 gaggatagat ttgatgagct acatcatctt caagaacagc acctgggaag gctgcgatag
    13561 ctgcttttac ttcttcgatt ggagccactt cttttgtttc gatataaaca gactcagagt
    13621 gagctgacaa gactggaata cgcacacatg ttgcagatac tgcaatgcta tcatcttcca
    13681 taattttctt agtttccttg gtcatcttca tctcttcgta cgtgtaatca ttatcagtga
    13741 aaacatcaat ttgtggaaga gcgttaaagg cgataggata atgtttcttg tcaccacctg
    13801 aaggcaaaat ttccgcatgc aaatcacatg gtttcacacc atcattcaag acttcacgaa
    13861 gttcacgttg tgtctcaaga attgctccca taccagcacc tgaaacggct tgataagttg
    13921 aaacaatgat acggtccaag ccccattttt ggcgaaccgg ctcaagagcc accatcattt
    13981 ggattgttga acaattaggg caggcaatga ttccgttgtg ggcatcaagt gcatgagcat
    14041 tgacctctgg aacaaccaaa ggaacatctg gattttgacg gaaataagat gtattatcca
    14101 ctactaccac gccagctttt actgcgtatg gtgcatactt agctgatgta gaactacctg
    14161 ctgaaaagag agcaatatca actccttcaa aagctgtttc agtcgtttct tcaattgtaa
    14221 tatcttgatc tttaaatttc aatgacttac ctgctgaacg tgcagaagca aggtaacgga
    14281 ttttatcgat tggaagtgtt gattcttcca acatttttat catctgagca ccgacagcac
    14341 ctgtcgcgcc gactacagca actgtatatc ccataaataa cctctttcgg aattttctaa
    14401 aaatttctat aatagaagta ttatactact ttttccatga attgcaaagc tttttcatca
    14461 ttttttggaa aataaaaatc ccagtcgcta gactagggac taagaggcat cttcatgtga
    14521 tgagcaggtt cacacaactc atcaaggtcc gctcctgcgt tatgacctcc ttatgctcaa
    14581 tagtagtccg aagactacct atcgactcat cgcatattct atattactag agatacttga
    14641 ttttgtcaat aagaaatttt ttcgatcgag tataacaaaa aactctcgta ttcaagagtt
    14701 tccctataca tatcatgcta attgccggga tcgaaccggc gacctcatcc ttaccatgga
    14761 tgcgctctgc caactgagct aaatcagctt acttaagaag tatactatat tcagaaaaac
    14821 ttgtcaagtt tccttagaaa ttttccatag gaaaaagcca ggtaagaact acctagctta
    14881 tcttcttcta tttacttaaa tcaattcgac gaccaatttt accaataata atcgccccaa
    14941 taatcaatga agcaaattca ccgattcctg ttgtaaacca agtaaggaag aatggtaatt
    15001 ctgctacaat atttaactct gcagcgatag taaacatgga aattgaaaag aggattgaaa
    15061 agaagaaatg atcttttcga atcaatccgt taaagaggta atccttgcta tattttgcaa
    15121 aaagccaaac acctaaactg aggaatacta aggttgaacc accaccaaca aagacatcta
    15181 gcagtccgaa gctaaagaaa ttagcaatca tacaaccgat ggtaactccg atgatgtact
    15241 taggattgta aaaagccata aagttcatca tttctgaaat acgaaactga taagcaccat
    15301 agctgatggc atttaggggc ggtgtgacag tcaaaacgac gtagatagca gcgacgattg
    15361 caatatctgc aatatcacga atagttaatt ttttcatctt ttctcctttg gcggttgccc
    15421 gcgtgtaata tgcttggtga aagaagctaa gcaccaaggg ttgctttatt caaccctact
    15481 agtatagcac aatagcctgc tttatgctat acttaacaca tgaaaattcc tattcaaaaa
    15541 ttttttaaca atgaaatctt agcctatctc ttttttggcc ttgcgacaac tctagtttcg
    15601 attctctcac gactagtcat ttatcaacta agtcatcagg aactcctggc tactgcccta
    15661 gcaaatatta tcggtatcct atttgccttt atcacaaatg atacgattgt atttaagcaa
    15721 aaaaagaaaa atagacttat ccgtttagtg aaattttctc ttgctcgcct ttctactttt
    15781 ctgttagact tgtttttaac ttttctcttt gtaacccaat ttcctcacat tatagggcaa
    15841 ttcgtaactg aaaacattga taagataaat gctattgaaa caataattgc acaaatattc
    15901 attattatca tcaattatat attgagcaag gcctatattt ttagaaaata atgctccatt
    15961 tatgagcctt ttaattgcct tctataatga tttaggatac aatgaaacac gaaacattga
    16021 aaggaaaaca gtatgttaaa aaatctaaaa tcgttcttgc ttcgaggaaa tgttattgac
    16081 cttgctgtcg gtgttgtaat tgcctctgct tttggtgcta tcgttacttc acttgtaaac
    16141 gacattatca ctcctcttat tttaaatccc gctttgaaag ctgctaaagt tgaacgtatc
    16201 gctcaacttt cttggcatgg agtcggctat ggtaacttct taagtgctat tatcaatttt
    16261 atctttgtgg gtaccgccct cttctttatt atcaagggca ttgaaaaagc acagaaactg
    16321 actggcataa agaaagaaaa aactgccgaa aaaaaaccaa ccgaattgga agtccttcaa
    16381 gaaataaaag ctctccttga gaaaaaataa tcgattaaaa ggatctagcg caaagctaaa
    16441 tccttttttc tttactcttt gggtaacttg cctgcttttt caagcatttt tttgatcaga
    16501 taaggcatct taacattctc ccgccctttt ttctcaatca gttttttcac aaattctggc
    16561 atttgtaaat cttcagattc agctaaaatg tttttcgtct cgtctgaagg aactaactca
    16621 tcaaaggtct cttcttctgg gagaaattcc ttaaactctt gattttcatt gactctaact
    16681 gtattgacca aagcatcaat caaacgagaa tctgtatttg gcattggtgg acgatggtag
    16741 tttaccccaa attcctggca taagtcataa cattctacat cattgtcaaa caagacctca
    16801 atatgctcac tgatgaaact aataggtaca aaaatataat ggtctggatg ttctgtctgt
    16861 tctctgagat actccaaaac atctggttta atccatggaa taccaatatc actctcactc
    16921 tgccaagtgt tggtatattg ttctgaactc aagcccagtt tttcagcgac tagcttgcta
    16981 ttttcgaaaa tttggtctat ataaggatca ccaaagtcca aggcaaaaat gggcacacta
    17041 tgggctgaaa agatgacttt aaagctgtct tgctttactt cttcttttaa aatcttagca
    17101 atttcatctg cccaatagtt taagagcact tcttcctgat accagtcctt aatgaccaaa
    17161 aattgaattt gtttgctttc taaaaatttt tcatagccca tgacagagta gaaagaataa
    17221 tggggctcca aaatcaagca gatacattct tcaacaccat cagtttccat ctgcttgatc
    17281 acgtctggaa taaagggacg agaaaatttg ttggcaaagt agataccgta ctcctcccct
    17341 aaacgttctt tgactaaatt gacctcctca cgtgtaatcc gctgcaaagg cgtcccaccg
    17401 atacgaatat agttgtcata gagagtctgg atttcgtggt cttggggtct aactccacga
    17461 cgaatgtttg taaagaattc tgctactcct tcaaaactaa tctcctctgg agatccaaag
    17521 gtcatcatta atatggcttt tttcatgtta tcatccttat gatattattt tctctatcca
    17581 ttctatcatg aaagaaaaaa atagtaaacg tttcctacgt ctactatttc ttttgctctt
    17641 ttgttttttt atctcgtctt ataattagga tgataaggac aagaagtaag aggacgataa
    17701 taaggagtag aaaggctaga atgtaaatcc aatgactggg aattccgtga tcgaaatacc
    17761 gtgttcctac tgcttcccca ctttcatcct gtgctacttt caccggtgca tccgttattt
    17821 tagctaaaag gatatgtcgt ccattagtta tgttaaggaa acatctcgct tgtacttggc
    17881 tttacttagc agatattgat agtaagcctg gtgttcctca tccttggaac tcaaggttcg
    17941 ataaatctcc gtgtcatagg catccacttc taaaatccca aaaatttcaa gaccacgttc
    18001 tcgaccattg tagtagatag aaccgtagcg atgctggtcg aagaattcct tatcagcaaa
    18061 tttcttaatc tcaccgaaca tagcccctga agccatagag tgtccgtaga tgatcgtatt
    18121 aaaatcagta aagttgggat taaagcgata gtcgagaaaa attgatccca ttatcgtata
    18181 atcgccaaag gcattgcggt caaggtattt gacattatcc tgactttgta gaagcggata
    18241 gtctaccttg gtcccatcaa ggctaatcca accgcaaaca tctttgttca agtgctgtag
    18301 ggtttcaaaa cctgtgctcg aagcatcctt ttcaatagga ttatagtgat catagtcact
    18361 tgcttctact actctctgcc aactaaaaag agctacaaaa acacagaaga ataccagaaa
    18421 tacgttttta aatcgcgctc ttttttgaac cgtcatcagc actcctttct atgcgagatt
    18481 tcttaaaagg aaaggaggcg ggacaaaacc gcctcttttc tattcaccct tagtcagtaa
    18541 aagggtctgc ttcttgcatt ttttttactc tctcttctac gacgtaggat caagtagagg
    18601 acaaggagta agaaaatcaa gagcaagaac aatacaaaca agataaggta ccaaatccat
    18661 agtgggattg atgagaggaa acgtccaaga gacgagtcat caaagacact gtatggaaat
    18721 ggttttgatt tttttgtatg gaaagtattt ttagggacgg tgtctgtaat ctttgcgact
    18781 acgatatgac gaccattggt cacatcgaga aaacaggtac tgagtaggat gatacgatca
    18841 ctcggtgaga gtgagatatc ccgcttgtgc atggcgactg agagcaggtg gtctagatag
    18901 gcctgctggc ggtcctcacc ctgtattcct ggatcataga tgttaaagtc ataggcatca
    18961 acctccaaca tctcaaagat ctcgagccct ttttccacac cattgtagta tatactaccg
    19021 taacgatgct ggtcaaaaaa ttcctgatca gcaaacttag ccacatcacc aaacatgacc
    19081 ccattttcta cgtggtgccc gtagataatg gtattaaagt cttcgaactt aggattattt
    19141 cgtgcatcga gaaagatagc gcctgtcgct gcaaactcac ctttggagtc cttgttgaga
    19201 tacttttcat tgtccttggc ttggactaag ggatagtcga tattggtgcc atagacattg
    19261 atccaaccga ggacttcggg attgagttct tggagtttgc tgaagcctga aaaactggcc
    19321 agctcatcct gttgcgtcgt gacaggtcga taagcttcgt actcacttga cgaagctaag
    19381 gagtagactt ggttggaatc ccaaagggcg tagaaaccaa agagaaagat caaagctgca
    19441 aaaatgagca gcaagtgatt gatcacccca tccacagcaa gaacgagacg cctagacaga
    19501 ctcttttttg gtttctcacg cttggttttc atcatctgcc cccagccgtt taggcttctc
    19561 tacgtttttt agacaagaca acaaatccag ccaaaccaag accaatcatc aaaatgaatg
    19621 gaaggttatc aatcaagaga ccagtaggag taacgtcgtc gattttgtta gtaactttgt
    19681 tgtcgttttt cttttcacct atgaggatat ctgttaatgt aaaatctaca tttttttgtc
    19741 cttgagatgt ttgttctgca ccatttgtag tataaattga tgaatctgta taacctgcta
    19801 ctccagtttc agttactgta tatttagaac ctgctggtag ttgttcaact gtaaatgttt
    19861 caccatcttt aagagtaaaa ttgtactcaa ctgtatctgc tggggtcact actgccaaca
    19921 cctctgactt agatccatgt tttactataa tattcgtaac aggggtttct gctgttttat
    19981 ttgtacttgg aagttgaatc ttgatatgga attggaaatc tcttgtttta tcccctgaag
    20041 ctccatcaac ttttttagta attgttaatg ctttcgcatt ggggtctact tgactcggat
    20101 catcaggatt aggctcctta cttgcgtctt tggtatatgt gttatcaaat aaattataaa
    20161 cgccttgttc acttggttct actttagggg cgttagattt attattttcc ttaaagtata
    20221 ctgatgaaat atagacacca ccatttactt tattcttaac aataacgtgc atttcatatg
    20281 tacgtttgtc gtatctcatg gcatcaattg ttttaccatt tttggtaatc gcctgccatc
    20341 cagtttttgc ttccgctaca tcataaacgt attcaccagc atggccataa gcaactcccg
    20401 aaaaaatgtc ttctgttgct ttttgaatct tatcagcagt tgggtgatca tttttattgt
    20461 attctacatt tctatctgga attgcaactc cggtttgata tggcgcaccg ttagaagatt
    20521 gtcctgtttt ttctgtaaac ttaaatgtaa atgtcgctgt tggtgttgtt attccctctg
    20581 caatattcaa cgttttatta atcttcacaa cagcattatt ttcaccattt gctttggtta
    20641 ttgctgaatt atcatccgca aaagtcggga cacctctgaa tacggacaaa gcggttatag
    20701 ctgcaatgct tgcagtgaat agctttttaa agaatgtttt tttcatgatt atttcttttg
    20761 tttttttatt ttcttttttc attatgatca tcaaaagcct cgtcttctaa tgactgttac
    20821 aactttgcct tgagtatcct gtatagggat ggttccaaaa gcacgactgt ctacagccgt
    20881 tgttcgattg tccccgagga caaaaagttg tcctgctggg actttcatcg ggaaggttgc
    20941 cccttcctta tagagcagcg tttctttgta gatatcttgc tcttgttgag gagaaccgtt
    21001 gatgatgaga ccattttcgt ttatatcgat tgtacttcct tcggttgcta tgacacgcgc
    21061 cactctttcc ttacctttat aactatagac tagcaaatca ccaatcgaat agcgtttatc
    21121 caacctataa tagacgacca agtcgccatc ttttaaggcg ggcttcatgc catcgtcatt
    21181 gtatcttaat aatccaaaga cgaaaaagta aaggatggct agtacaaatc caaccatcag
    21241 aagtttactg actaagtaaa ggatatctcc ccagacactc ggcggagact tatcccgatt
    21301 gacttgtgtt actggtttct tatgtttctt tttaagcagc atcacttcct cctattcacc
    21361 acaaggtgac caagtaagat gataaagaag atccctccta gaggaagaac gactccaagc
    21421 acgagagtgc tactcaagaa gtcaattccc gtttcaggta cgctgttttt attattcgtg
    21481 actgtcgcag acttatttgc atcaagagtt ccttcttttt tatcatagga cacctgatac
    21541 ccacgagacg aacttgcttc ttcttcgata ctataacgag catttagagg aaggtcgaga
    21601 atcttgatgg ttttatcttt ctttagatca actgtcgcct taccattggt gaattgtagc
    21661 gttgtttttt gattatttac tattgcacta tacgatccat tcaatggttt attttgcgca
    21721 tcctttacgt taatggtaat cttaaaggat tgcagaagat tagcaaaagc acctgtaact
    21781 ttttttgtga ctgaaagtgt cggaagtctg tggttggtga cgattgtttg aacatcctct
    21841 gacaaagtcc cctcttgttt ttcataggtg acatgatatc ccgttctaga gttctctact
    21901 tcttccacct tatagtgggt atcacgaggc agataactga gggcagtttc ctgactattt
    21961 ttgagagaaa tctgtgcttt cccgttagtc actgttgtat tcccaaactt gccgttaatc
    22021 ggcttgccat ccttatctga aaaggtaaca ttaattgtga aagatttatt aggtgattgt
    22081 tcaccttcta ggattttctt tacggtgaga cttggaagct gtcggtaaat aactttgaag
    22141 gatggtttct ctttcgtacc tgtcttttga acttcgactg tgtatcccgg agcgtctggt
    22201 gctttcagtt cgtagtcata tcccttagct acctttgcaa aactagtatt ttcagtaaaa
    22261 ctattcgttt gaactggact agtgaccttt cgataggaat cctttatact tccatctttc
    22321 ttttggttta agtttaattc gacactaggt ggacgatttg ctgatggatt tgattttcca
    22381 tccacacctt tccactcaat ctctacagga accgtcaatg gatctgacgg cttgaaagtg
    22441 ggcttctcag aatagtcttt tattttggta cgtgaggtcc caataccata ggaataggca
    22501 acttttgccc ccttgttgga gtagagttta gtagcatcgg cttcttcggc atcatcacta
    22561 gtaagtgtct tatcacccgc aatcgcatca aatgcctctt ggctagaggt gacagtaaac
    22621 ttgagaacgt acttggcgtc atcctccaaa gtgtaactcg gattaaactt ggctgttact
    22681 tccactaatc cctgttcgtt cttcttagtt tcaatcgtaa cttgattgtc attcagttct
    22741 tgctcgttac catccttgat tttgacgaca cgaaggtgtg aagcatcacc aggtaacagc
    22801 tgcacgtact tggacaagac atctgatata gttacatggt gtacgcctag aggtagaatt
    22861 ttatctgtga tttctttgaa tttttgttgc aagtcatttt cattattggc agaaaatatt
    22921 tcgttgggga ttccagaatt ataaccactg atatatcctt taagagatgt gatactatcg
    22981 tttgaaccta tataatatct gaatttgatt gaataaaagc catctatttt tggagctatt
    23041 aaactagata tattcagcat tcctctttct aaaccagagg taaaccaata tggagtatca
    23101 atcatacgtc ccacatttgg attagaataa tagttatata ttgttctccc actattagac
    23161 tcgtaataca tattagcttc gccatctgac agcagaataa ctactttttt tgccccagcc
    23221 cttgcacttt gcaacaatct ttgagcttca gttaacccag catttatatt tgtcccagtg
    23281 ccaatgcccg cgtccatacc ataagaacga ctagagtcag caattgttaa cgaactaaca
    23341 atattttttg agctattaga atccgtgctc caagatacta aagttttagc atcatcatat
    23401 gaagagatat ttgaatacca accagctcaa tttggccaag ttccatattg ataactcaga
    23461 taatattcat tataataacg gtcattatac tgattatcaa tctttccggc aaaaccaact
    23521 atagacagac ggttttggga attagaaaga attgtatcaa tgagcccctg acgaccattc
    23581 acacctttca gtgtatgttt tagtgcttca atcctactaa tgtatcgtct actagagtaa
    23641 gaccacacat ctcgctcttc catactccct gaaagatcgg caaccaagac tacatccaag
    23701 ggttctgact gggtctccgt tcccagttta gatgtgatat ccagtgacaa ctcatactgg
    23761 tctttttgcc ctgatatcgg agtaatcgtt ttgtgcagag ttgtctgagg ttcagttatt
    23821 gaatctgcac gtaaagaatt aattggtgca cacaaaaaaa gaatagcgag aaagataact
    23881 aaactactgg taaaatattg aatcttctta aaatcatatt gaacgttcat gctatctccc
    23941 ttgctagaat atgttttaat ctgatactat ataaatctga gacttccata agataattgt
    24001 ataataatat taacttcgtg tcaattaatg tgtttgaaaa catgttatta taaattacaa
    24061 aaaagtatga ttcttctttg tttttcaact ttttctgtgg taaaatggaa aaaatagtaa
    24121 aaaatttcat aaaataaaga tgcatatatt tattctaatc gctcgaaaat ttcttttgaa
    24181 agtcttctga atttgaatta ttatattttt tcaaaattca taaaatttct caaatcatat
    24241 ttttccgaag ttttgtattc tattttatga taaaaaagga gtttttttat gacttatcca
    24301 aatctcttgg accgcttctt aacctacgtt aaggtcaaca cgcgctctga tgaacactct
    24361 actactactc caagtacaca gagtcaggtt gacttcgcaa caaatgtcct aattcctgaa
    24421 atgaaacgtg ttggactgca aaatgtttac tatctaccga atggttttgc tattggaacc
    24481 ttgccagcca acgatccgtc tttaacacgt aagattggtt ttatatcgca catggatact
    24541 gctgatttta atgctgaagg agtcaatcca caggtaattg aaaactacga tggtggtgtg
    24601 attgaactag ggaattctgg tttcaaactc gatccagccg acttcaagag tcttgaaaaa
    24661 tatccaagac aaacactcat cacaacagat ggaacaacct tgctaggtgc tgatgacaag
    24721 tcaggaattg ctgaaattat gacagccatt gaatatctaa ctgctcatcc tgaaattaag
    24781 cactgtgaga ttcgtgttgg ttttggtcca gatgaagaaa tcggtgttgg tgccaataaa
    24841 tttgatgcag aagattttga tgtggatttt gcctacactg ttgatggtgg tccactaggt
    24901 gaacttcagt acgagacttt ctcagccgct ggtgctgaat tgcatttcca aggccgtaat
    24961 gtccaccctg gtactgccaa agggcagatg gtcaatgccc ttcagctagc aattgatttt
    25021 cataatcaac ttccagaaaa tgaccgacct gagttaactg aaggttacca aggtttttac
    25081 catctaatgg atgtgacagg tagtgttgag gaggtgcgtg caagctacat cattcgtgat
    25141 tttgaaaaag atgcctttga agcgcgtaaa gcatccatgc aatctatcgc tgataagatg
    25201 aatgaagaac ttgggagcga ccgtgtcact ctcaacttga cagaccagta ctacaatatg
    25261 aaagaagtca ttgaaaaaga tatgactcca attaccattg ctaaagccgt tatggaagat
    25321 ctaggtatca cgcctattat cgaaccaatc cggggtggaa cagacggctc taagatttcc
    25381 tttatgggaa tcccaactcc gaatatcttt gcaggtggcg aaaatatgca cggacgtttt
    25441 gaatacgtta gccttcagac tatggaacgt gcagttgata ccatcattgg catcgtagct
    25501 tataaaggct aaaaagacga ggtggctcag ctacttcgcc tttcttttta ttctactggt
    25561 ttttcttgat ttccagtagt tgtagaagat tctgttgttt cattttctga agttgattca
    25621 gcaggtttag aatctcttgt attgcttggt ttgttttcgt cgctagcagt ttcaatgtta
    25681 gattctgcag ttgcgtttgg ttggttctca gcactggtgt tatcactatt tgcttcagca
    25741 tttcttgctg gacttgtttc ttcacttgcg ctaacttttg actggatttg atgattcaaa
    25801 actagaatag cttttgtcga ttcaagtaaa gctgttttgt ctttactatt agcagaaagt
    25861 tgatctaata atgcatccac cttatcaaag tccgcatcag atccattatt actttctaaa
    25921 taagagtgaa gcgacatgag aatatcgtag agtttttgat agagtacaag tgtctgagaa
    25981 tcttgctcag cattttcctt ttcttgttga agggcgctag cgatacgagt caaaacatct
    26041 tttacctgac tgtttacttc atccaagtct gcatcagcct tgtttgtggc agcttttaga
    26101 ttttctactt cttctgccaa ggattgtctg attccttctt catggatttg ttccaagagt
    26161 tgatttgcct tgttcaaaag actttctact tcttccttgc tatctgtcgc agattattgg
    26221 ttgctatcta ccatgtactc ctaaaacagg agagttataa tccaagatta caaggcctta
    26281 cagaaataag aaatccagat aagacaatgt tcgtccaaga cgctattcgc ttcgcacagc
    26341 agcacggatt caatatgctt taattttaaa gtttaggtgt caagacctct ttttagtgtg
    26401 cccaaaattt agagaagtaa tcaatcaact aacttttatt tttttcaaac tttcagtaaa
    26461 ctgacctaaa gctaactcaa tctgtctttg tagatgcttc tgctatcagc tagaagttga
    26521 tctacttttg ccaagactgc cttctcatca aaagttccag gttgatagtt ggattgcagg
    26581 gatggaatct tgtttttcaa agccgcttca tatcccttag tttgaacctt gatgtagtga
    26641 ttgtggtcgc catgaggaat cacaaaacct tctgaatctt cacttataat tcgattggca
    26701 tcaaaaacca taaccatctt cttcctcatg gtggacatgt agtgacggat tacttaatac
    26761 agaactagaa gaacttccta cctcttccgt gttagagtgt gatgggggat tgttaagaga
    26821 tgacttagga atatagtgat agtgttcccc atgtcttact atataagcat cacctatatc
    26881 tctgacaata tcattagggt taaagacata tgtggctgct aattcacctg ccgacaagtc
    26941 actctcagga atgaaatgat agtgaccacc atgtggtact attagtagat tgaaatagaa
    27001 tatgagcaaa ttgataaggg gattttaaag taatttctaa caatgattta gaaactatga
    27061 tgtgctattc taaattcaac tcactatata taaccatcat cggtagtata acgtccctgt
    27121 aattttgcta cagatacttc tgcactagct cctttatcgt ctttaccatg ttcttgtttt
    27181 tggcgattga tttcatcttt tgttcgtaca ttttctgcat gagcttgatc tttaaggtaa
    27241 acataatact ttccatctac cttaataata tatcctccct taacctaact gacaatatct
    27301 tgatctttcg gctgatagtt gggggctttc attaatggct cttcactaaa gagcgcatca
    27361 aaaggaactt taccattata gtagtgataa tgatcgccat gagaagttac ataaccttga
    27421 tctgtaatct taataacaat ttgttttgct tgaattcctt ctttttgact aacctagtct
    27481 ggagtcaaat tttcagtctt cttagtgtct ttattactgt ttacatatga aacacgattt
    27541 ttatctgtat tggcctgtta gctatgttgg ttcagagcat aaacacacag acttaaggaa
    27601 aggataacaa cagatccagc tgctatatat ttctttttaa atttcataat tacctcattt
    27661 ctataattat ttatatgatg tcttcattat taaatgatta tagaaattaa ttaaccaatt
    27721 aattaactag taaatattcc acctcttttt aagttgtatg tcaagaaatt ttatatatta
    27781 ataataaaat gaaattctcc caaagtcaga gttttatttc taacttttga gagaacttca
    27841 tttttgattc agactttttc tactgctatt ccttacgcta tgagatcaga taaattcttt
    27901 tttatcactt ctccacttgg caatcttaat tcaatcgttc catccatatt gaatataaca
    27961 ctatctaagc ctaatccgta actagctgta aatttttcta atttttcttg tacaggatct
    28021 actgctggag cttcctctaa tgctggatct aacatagggt cactccccac attcccttct
    28081 ggattcaaca ttccattatc cgttgagttt tctggtttta caggtttttc gtttggtgcc
    28141 tctggtaaag aatctgctgg tttattttct gttggttggt tctcaactgt tccagtagat
    28201 acttttccat tttcagatgg tttattttca ccatttcctt gaggtgcttc tcctgtaaaa
    28261 tctgccatat tctttttaat gacttctccc gatggtaaat ataattcaat tgttccgtcc
    28321 atattaaaca agacattttc tagcttcatc ccataacttt cagcaaattt tgctactttt
    28381 tcttgtacag gatccactgt aggaacttct tctaacgttg aattactagt actattccca
    28441 gtttcagaaa gtttttcttt ttctaccttc tcactagtct ttggttcttc taccttttca
    28501 tcaagttttg agttttcttg tgctttattc cttttaaatt gtggtagaat acttggttta
    28561 tcagtttgat tttctttttc caagataggt acttccacaa tataagtcga ttgattgtcc
    28621 aaataagcat ttgccatgaa ggttacagga attttatttc cggccgttct ggttgttcct
    28681 tggtttaatt tcggaatcgg taatttgatt tcaccaactt tatagttatt ttctaaataa
    28741 gcatttccat gaaattcatc aaacactctg actaaagcat cagttccttt aggcactgca
    28801 aattgagggt tcactcttaa ataagtatcc cctgcatgga aaggatagaa aatcgtttga
    28861 ctggccattt tgtaagctaa agaggttgga actgtaaatg taccatcata acttacttct
    28921 ggataatctt ttgaagcgat agtatactta aatgtttgtc ctggtaaata aggttgatct
    28981 aattcaaagt ttgcaatatt ccctactcct tctccaaata ctttaccaga tactttctcc
    29041 aatacttttc catctggtgt tattaatttt actagcatat tgatacctaa ttttttctcc
    29101 aattcaggcg gaaaactaaa agaaacgcgt ttttgaccat tggctagagt aaagttttga
    29161 ttattaaacg tactattttt taacaaatta acaacattcg ttaattcttc tccagtataa
    29221 actttattcc cttctttttt agcaactcct tcttcgggtt taaacagttc atagttactg
    29281 tgagaatgac caattccaac cggtttatgt tcatcaatcg gatctgcatg atggtgatct
    29341 ccatgcggat aaataatcgc atttttttct ttattcacga caatactttc acgtttgaca
    29401 ccatattgtt tcataatgcc agcaattttt tcttcgattt ttttatctaa atctttcatt
    29461 tctttggcat tacttggata atcctgttca tgagatgaca aagaatctaa tccattatga
    29521 ctagttttaa cttcctctaa atgtttttgc gcagccttaa tttgctcttc tgtcaagtcc
    29581 ttcttgaaga aataatgatt gtggtctccg tgactcatga caaaacctga ttcatcttca
    29641 gcgataatac gattagcatc aaatccgtat ccatcttctt catgtttctc atgtgaagtt
    29701 cctggattga ttggaagaga tggagaaggt gttgctagac tattgtttgg aagagtcggt
    29761 tgcccaattt gatttgattt tggaatgtaa tggaaatgat caccatgtct tacaatataa
    29821 gctgtagccg tttcttcaac gatatctttt ggattaaaaa tataaccatc agatgctgaa
    29881 gagagctcct tacttgtcgt taaagaagaa ggattgcttg aaagactgcc tagactagac
    29941 actacttcat taggttttgc atttgtagaa actgtagaac cagttccact gataggcacc
    30001 attctggcaa tcttttcttc taaggcagaa agcttgctgt aaggaataaa gtggtaatgg
    30061 tcgccatgcg gaatcgcaac tccatttggt gtacgactga taatcttagc agggtcaaag
    30121 accaggccat ctgattcact gtaacgttgg gcgctaggtg aatcatagag ttccttcaaa
    30181 agactctgga gattttcaga tttatttgct ggcttgctag ttgatccttt tgctacagat
    30241 tgcgtgttat tgtcactagc tgttgaagaa tagcttaact gactcggttg catatttttt
    30301 ccagccagat gtgctttagc tgctgctaat tcactagcag ataaatcgct tttgggaatg
    30361 tagtgatagt gacctccatg aggaacgata taagcattac ccgtatcttc gataatatca
    30421 gctggattaa agacataacc atcatttgtc gtatatcgtc cctgagacct tgctacagca
    30481 acattagagt taaccttctc attatctttg acatgttctt gtttttgacg attgatttca
    30541 tctttagttc gaacattatc agcatgagct gcatctttca ggtagacata atattttcca
    30601 tcgaccttga tgatataacc acccttgact tcattgacaa tatcagcgtc tttaagttga
    30661 tagtttggat ccttcatcaa gagttcttca ctaaagaggg catcataagg aactttccca
    30721 ttatagtaat gatagtggtc accgtgtgac gttacatagc cctgatctgt aattttgatt
    30781 acaatttgct cggcctgaat tccttctttc tggctaatct ggtctggtgt caagttttca
    30841 cttttctgac ttgactggct gccatctaca taagagacac gattattgtc cttattttcc
    30901 tgcgaacgat gctggtttag tgcataggca catagactca aggatacgat aacagctgat
    30961 ccagctgcta tatatttttt actgaatttc ataaatccct ca
//
LOCUS       DAVBEO010000022        30742 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 009
            SAMEA1678075-rid20185393.denovo.022, whole genome shotgun sequence.
ACCESSION   DAVBEO010000022 DAVBEO010000000
VERSION     DAVBEO010000022.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678075
            Sequence Read Archive: ERR226392
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 30742)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 30742)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980207.1
            Genome Coverage       :: 150x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:50:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 72 of 147
            Pseudo Genes (incomplete)         :: 72 of 147
            Pseudo Genes (internal stop)      :: 42 of 147
            Pseudo Genes (multiple problems)  :: 32 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30742
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678075-rid20185393.denovo.022"
                     /strain="KS 009"
                     /db_xref="taxon:1313"
     gene            16..210
                     /locus_tag="VQ543_001025"
     CDS             16..210
                     /locus_tag="VQ543_001025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001244258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HET2611759.1"
                     /translation="MGAEAIRRNCERGAIFSGKIKHHEDSQFKGDHYVECYAVLDNTV
                     IARDRITVPIDPLCGKDFIE"
     gene            554..1888
                     /gene="trmFO"
                     /locus_tag="VQ543_001026"
     CDS             554..1888
                     /gene="trmFO"
                     /locus_tag="VQ543_001026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000083696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate--tRNA-(uracil(54)-
                     C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO"
                     /protein_id="HET2611760.1"
                     /translation="MSQSYINVIGAGLAGSEAAYQIAERGIPVKLYEMRGVKSTPQHK
                     TDNFAELVCSNSLRGDALTNAVGLLKEEMRRLGSVILESAEATRVPAGGALAVDRDGF
                     SQMVTEKVANHPLIEVVRDEITELPTDVITVIATGPLTSDALAEKIHALNDGDGFYFY
                     DAAAPIIDVNTIDMSKVYLKSRYDKGEAAYLNAPMTKQEFMDFHEALVNAEEAPLNSF
                     EKEKYFEGCMPIEVMAKRGIKTMLYGPMKPVGLEYPDDYTGPRDGEFKTPYAVVQLRQ
                     DNAAGSLYNIVGFQTHLKWGEQKRIFQMIPGLENAEFVRYGVMHRNSYMDSPNLLEQT
                     YRSKKQPNLFFAGQMTGVEGYVESAASGLVAGINAARLFKEESEAIFPETTAIGSLAH
                     YITHADSKHFQPMNVNFGIIKELEGERIRDKKARYEKIAERALADLEEFLTV"
     gene            1972..2709
                     /locus_tag="VQ543_001027"
     CDS             1972..2709
                     /locus_tag="VQ543_001027"
                     /EC_number="2.7.4.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000013002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UMP kinase"
                     /protein_id="HET2611761.1"
                     /translation="MANPKYKRILIKLSGEALAGERGVGIDIQTVQTIAKEIQEVHSL
                     GIEIALVIGGGNLWRGEPAAEAGMDRVQADYTGMLGTVMNALVMADSLQQVGVDTRVQ
                     TAIAMQQVAEPYVRGRALRHLEKGRIVIFGAGIGSPYFSTDTTAALRAAEIEADAILM
                     AKNGVDGVYNADPKKDKTAVKFEELTHRDVINKGLRIMDSTASTLSMDNDIDLVVFNM
                     NQSGNIKRVVFGENIGTTVSNNIEEKE"
     gene            2718..3275
                     /gene="frr"
                     /locus_tag="VQ543_001028"
     CDS             2718..3275
                     /gene="frr"
                     /locus_tag="VQ543_001028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome recycling factor"
                     /protein_id="HET2611762.1"
                     /translation="MANAIIEKAKERMTQSHQSLAREFGGIRAGRANASLLDRIHVEY
                     YGVETPLNQIASITIPEARVLLVTPFDKSSLKDIERALNASDLGITPANDGSVIRLVV
                     PALTEETRRDLAKEVKKVGENAKVAVRNIRRDAMDEAKKQEKAKEITEDELKTLEKDI
                     QKVTDDAVKHIDDMTANKEKELLEV"
     gene            3335..4189
                     /gene="cvfB"
                     /locus_tag="VQ543_001029"
     CDS             3335..4189
                     /gene="cvfB"
                     /locus_tag="VQ543_001029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001095444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding virulence regulatory protein CvfB"
                     /protein_id="HET2611763.1"
                     /translation="MNTNLASFIVGLIIDENDRFYFVQKDGQTYALAKEEGQHTVGDT
                     VKGFAYTDMKQKLRLTSLEVTATQDQFGWGRVTEVRKDLGVFVDTGLPDKEIVVSLDI
                     LPELKELWPKKGDQLYIRLEVDKKDRIWGLLAYQEDFQRLARPAYNNMQNQNWPAIVY
                     RLKLSGTFVYLPENNMLGFIHPSERYAEPRLGQVLDARVIGFREVDRTLNLSLKPRSF
                     EMLENDAQMILTYLESNGGFMTLNDKSSPDDIKATFGISKGQFKKALGGLMKAGKIKQ
                     DQFGTELI"
     gene            4198..4413
                     /locus_tag="VQ543_001030"
     CDS             4198..4413
                     /locus_tag="VQ543_001030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YozE family protein"
                     /protein_id="HET2611764.1"
                     /translation="MRKSFYTWLMTERNPKSNNPKAILADLAFEEAAFPKHTDDFDEV
                     SRFLEEHASFSFNLGDFDSIWQEYLEH"
     gene            4499..5467
                     /locus_tag="VQ543_001031"
     CDS             4499..5467
                     /locus_tag="VQ543_001031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhoH family protein"
                     /protein_id="HET2611765.1"
                     /translation="MKEHSIDIQLSHPDDLFHLFGSNERHLRLMEEELDVVIHARTEI
                     VQVLGEESACEEARQVIQALMALVNRGMTVGTPDVVTAISMVKNDEIDKFVALYEEEI
                     IKDNTGKPIRVKTLGQKLYVDSVKQHDVTFGIGPAGTGKTFLAVTLAVTALKRGQVKR
                     IILTRPAVEAGESLGFLPGDLKEKVDPYLRPVYDALYQILGKDQTTRLMEREIIEIAP
                     LAYMRGRTLDDAFVILDEAQNTTIMQMKMFLTRLGFHSKMIVNGDISQIDLPRNVKSG
                     LIDAQEKLKNIHQIDFVHFSAKDVVRHPVVAQIIRAYEYSTEVAHD"
     gene            5647..6147
                     /locus_tag="VQ543_001032"
     CDS             5647..6147
                     /locus_tag="VQ543_001032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000566985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET2611766.1"
                     /translation="MIDQLSKYYSCRILTEKDIPSILSLYESNPLYFQHCPPEPNFAT
                     VKEDMLCLPEGKAKADKFFVGFWNGSDLVAVMDFVYAYPDEETVFIGLFMVDQAYQRK
                     GIGSHIVTEALAYFAKNFRKARLAYVKGNPQSQHFWEKQGFKSIGCEVKQELYTVVIA
                     EQSLED"
     gene            6150..6410
                     /locus_tag="VQ543_001033"
                     /pseudo
     CDS             6150..6410
                     /locus_tag="VQ543_001033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003069408.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TfoX/Sxy family protein"
     gene            complement(6777..7888)
                     /gene="ald"
                     /locus_tag="VQ543_001034"
                     /pseudo
     CDS             complement(6777..7888)
                     /gene="ald"
                     /locus_tag="VQ543_001034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004253293.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="alanine dehydrogenase"
     gene            8065..8634
                     /locus_tag="VQ543_001035"
     CDS             8065..8634
                     /locus_tag="VQ543_001035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000443767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET2611767.1"
                     /translation="MESIFVKFAQYPSIETERLLLRPVTLDDAEAMFDYASDKGNTRY
                     TFPTNQSLEETKNNIAQFYLANPLGRWGIELKDNGKFIGTIDLHKIDPVLKKAAIGYI
                     INKKYWNQGLTTEANRAVIELAFEKIGMNKLTALHDKANPASGKVMEKSGMRFSHAEP
                     YACMDQHEKGRIVTRVHYVLTKEDYFANK"
     gene            8702..9352
                     /locus_tag="VQ543_001036"
     CDS             8702..9352
                     /locus_tag="VQ543_001036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000387331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-hairpin-helix domain-containing protein"
                     /protein_id="HET2611768.1"
                     /translation="MEAIIEKIKEYKIIVICTGLGLLVGGFFLLKPAPQTSVKETNLQ
                     AEVAAVSKDSSTGKEVNKEEKEEPVEQDLITVDVKGAVKSPGIYDLPVGSRVNDAVQK
                     AGGLTEQADSKSLNLAQKVSDEALVYVPTKGEEAVSQQTGSGTASSTSKEKKVNLNKA
                     SLEELKQVKGLGGKRAQDIIDHREANGKFKSVDELKKVSGIGAKTIEKLKDYVTVD"
     gene            9336..11576
                     /locus_tag="VQ543_001037"
     CDS             9336..11576
                     /locus_tag="VQ543_001037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA internalization-related competence protein
                     ComEC/Rec2"
                     /protein_id="HET2611769.1"
                     /translation="MLQWIKNFSIPLIYLSFLLLWLYYAIFSVSYFALLGFVFLLVCL
                     FIQFPWKSAGKVLVICGVFGFWFLFQTWQQSQVSQNLVDSVERVRILPDTIKVNGDSL
                     SFRGKSDGRAFQVYYKLQSEEEKEAFQALTDLHEIGLEGKLSEPEGQRNFGGFDYQGY
                     LKTQGIYQTLNIKRIQSLQKVGSWDIGENLSSLRRKAVVWIKMHFPDPMRNYMTGLLL
                     GHLDTDFEEMNELYSSLGIIHLFALSGMQVGFFMDGFKKLLLRLGLTQEKLKWLTYPF
                     SLIYAGLTGFSASVIRSLLQKLLAQHGVKGLDNFALTVLVLFIVMPNFFLTAGGVLSC
                     AYAFILTMTSKEGEGLKAVTSESLVISLGILPILSFYFAEFQPWSILLTFVFSFLFDL
                     VFLPLLSILFVLSFLYPVIQLNFIFEWLEGIIRLVSQVASRPLVFGQPNEWLLILLLI
                     SLALVYDLRKNIKKLTVLCLLITGLFLLTKHPLENEITMLDVGQGESIFLRDVTGKTI
                     LIDVGGKAESYKKIKKWQEKMTTSNAQRSLIPYLKSRGVAKIDQLILTNTDKEHVGDL
                     SEMTKAFHVGEILVSKDSLKQKEFVAELQATQTKVRSMIVGENLPIFGSQLEVLSPRK
                     MGDGGHDDTLVLYGKFLDKQFLFTGNLEEKGEKDLLKHYPDLKVNVLKASQHGNKKSS
                     SPAFLEKLKPELTLISVGKSNRMKLPHQETLTRLEGINSKVYRTDQQGAIRFKGLDSW
                     KIESVR"
     gene            11756..11944
                     /locus_tag="VQ543_001038"
     CDS             11756..11944
                     /locus_tag="VQ543_001038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2611770.1"
                     /translation="MTVTKSYKYDWNTVLEYSTNYHDHQYAWIPEWSRYYSYSEYKVG
                     GGWNYARYEVINYYTGGY"
     gene            11976..12563
                     /locus_tag="VQ543_001039"
     CDS             11976..12563
                     /locus_tag="VQ543_001039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000939891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2611771.1"
                     /translation="MLNLTHVTLKTRQVILQDADFTFKKGRIYGLLAINGSGKTTLFR
                     AMSKLLPLSSGHIAVPPSLFYYESVEWLDGNLSGMDYLRLIKNIWKSDLNLRDEIAYW
                     EMADYISLPIRKYSLGMKQRLVIAMYFLSQAKCWLMDEITNGLDEYYRQKFFDRLAQI
                     DRQEQLVLLSSHYKEELVDICDRVVTIHQGQIEEV"
     gene            12567..13742
                     /locus_tag="VQ543_001040"
     CDS             12567..13742
                     /locus_tag="VQ543_001040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000655966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2611772.1"
                     /translation="MKDVSLFLLKKVFKSRLNWIILALFVSVLGVTFYLNSQTANSHS
                     LESRLESRIAANERAINENEEKLSQMSDTSSEEYQFAKNNLDVQKNLLTRKTEILTLL
                     KEGRWKEAYYLQWKDEEKNYEFVSNDPTASSGLKMGVDRERKIYQALYPLNIKAHTLE
                     FPTHGIDQIVWILEVIIPSLFVVAIIFMLTQLFAERYQNHLDTAHLYPVSKVTFAISS
                     LGVGVGYVTVLFIGICGFSFLVGSLISGFGQLDYPYPIYSLVNQEVTIGKIQDVLFPG
                     LLLAFLAFIVIVEVVYLIAYFFKQKMPVLFLSLIGIVGLLFGIQTIQPLQRIAHLIPF
                     TYLRSVEILSGRLPKQIDNVDLNWSMGMVLLPCLIIFLLLGILFIERWGSSQKKRIF"
     misc_feature    13916..14047
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00558"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L20 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00558"
     gene            14063..14593
                     /gene="infC"
                     /locus_tag="VQ543_001041"
     CDS             14063..14593
                     /gene="infC"
                     /locus_tag="VQ543_001041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000848185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-3"
                     /protein_id="HET2611773.1"
                     /translation="MKTIAKQDLFINDEIRVREVRLIGLEGEQLGIKPLSEAQALADN
                     ANVDLVLIQPQAKPPVAKIMDYGKFKFEYQKKQKEQRKKQSVVTVKEVRLSPTIDKGD
                     FDTKLRNARKFLEKGNKVKVSIRFKGRMITHKEIGAKVLAEFAEATQDIAIIEQRAKM
                     DGRQMFMQLAPATDKK"
     gene            14626..14826
                     /gene="rpmI"
                     /locus_tag="VQ543_001042"
     CDS             14626..14826
                     /gene="rpmI"
                     /locus_tag="VQ543_001042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001125942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L35"
                     /protein_id="HET2611774.1"
                     /translation="MPKQKTHRASAKRFKRTGSGGLKRFRAYTSHRFHGKTKKQRRHL
                     RKASMVHSGDYKRIKAMLTRLK"
     gene            14878..15237
                     /gene="rplT"
                     /locus_tag="VQ543_001043"
     CDS             14878..15237
                     /gene="rplT"
                     /locus_tag="VQ543_001043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019786714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L20"
                     /protein_id="HET2611775.1"
                     /translation="MARVKGGVVSRKRRKRILKLAKGYYGAKHILFRTAKEQVMNSYY
                     YAYRDRRQKKRDFRKLWITRINAAARMNGLSYSQLMHGLKLAEIEVNRKMLADLAVND
                     AVAFTALADAAKAKLGK"
     gene            15295..15675
                     /locus_tag="VQ543_001044"
     CDS             15295..15675
                     /locus_tag="VQ543_001044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HET2611776.1"
                     /translation="MASKMLHTCLRVENLEKSIAFYQDAFGFKELRRRDFPDHAFTIV
                     YLGLEGDDYELELTYNYDHGPYVVGDGFAHIALSTPDLEALHQEHSAKGYEVTEPNGL
                     PGTTPNYYFVKDPDGYKVEVIREK"
     gene            15925..16725
                     /locus_tag="VQ543_001045"
     CDS             15925..16725
                     /locus_tag="VQ543_001045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase electron transfer
                     subunit"
                     /protein_id="HET2611777.1"
                     /translation="MNPTCKKRLGVIRLETMKVVAQEEIAPAIFELVLEGEMVEAMRA
                     GQFLHLRVPDDAHLLRRPISISSIDKANKQCHLIYRIEGAGTAIFSTLSQGDTLDVMG
                     PQGNGFDLSDLDEQNQVLLVGGGIGVPPLLEVAKELHERGVKVVTVLGFANKDAVILK
                     TELAQYGQVFVTTDDGSYGIKGNVSVVINDLDSQFDAVYSCGAPGMMKYINQTFDDHP
                     RAYLSLESRMACGMGACYACVLKVPESETVNQRVCEDGPVFRTGTVVL"
     gene            16688..17674
                     /locus_tag="VQ543_001046"
     CDS             16688..17674
                     /locus_tag="VQ543_001046"
                     /EC_number="1.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013193458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase"
                     /protein_id="HET2611778.1"
                     /translation="MVLFSAQEQLYYKEKIMTTNRLQVSLPGLDLKNPIIPASGCFGF
                     GQEYAKYYDLNLLGSIMIKATTLEPRFGNPTPRVAETPAGMLNAIGLQNPGLEVVLAE
                     KLPWLEREYPNLPIIANVAGFSKQEYAAVSHGISKATNVKAIELNISCPNVDHCNHGL
                     LIGQDPDLAYDVVKAAVEASEVPVYVKLTPSVTDIVTVAKAAEDAGASGLTMINTLVG
                     MRFDLKTRKPILANGTGGMSGPAVFPVALKLIRQVAQTTDLPIIGMGGVDSAEAALEM
                     YLAGASAIGVGTANFTNPYACPDIIENLPKVMDKYGISSLEELRQEVKESLR"
     gene            17716..19617
                     /locus_tag="VQ543_001047"
     CDS             17716..19617
                     /locus_tag="VQ543_001047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HET2611779.1"
                     /translation="MNLGEFWYNKINKNRGRRLMKKVRFIFLALLFFLASPEGAMASD
                     GTWQGKQYLKEDGSQAANEWVFDTHYQSWFYIKADANYAENEWLKQGDDYFYLKSGGY
                     MAKSEWVEDKGAFYYLDQDGKMKRNAWVGTSYVGATGAKVIEDWVYDSQYDAWFYIKA
                     DGQHAEKEWLQIKGKDYYFKSGGYLLTSQWINQAYVNASGAKVQQGWLFDKQYQSWFY
                     IKENGNYADKEWIFENGHYYYLKSGGYMAANEWIWDKESWFYLKFDGKIAEKEWVYDS
                     HSQAWYYFKSGGYMTANEWIWDKESWFYLKSDGKMAEKEWVYDSHSQAWYYFKSGGYM
                     AKNETVDGYQLGSDGKWLGGKATNENAAYYQVVPVTANVYDSDGEKLSYISQGSVVWL
                     DKDRKSDDKRLAITISGLSGYMKTEDLQALDASKDFIPYYESDGHRFYHYVAQNASIP
                     VASHLSDMEVGKKYYSADGLHFDGFKLENPFLFKDLTEATNYSAEELDKVFSLLNINN
                     SLLENKGATFKEAEEHYHINALYLLAHSALESNWGRSKIAKDKNNFFGITAYDTTPYL
                     SAKTFDDVDKGILGATKWIKENYIDRGRTFLGNKASGMNVEYASDPYWGEKIASVMMK
                     INEKLGGKD"
     gene            complement(19678..21333)
                     /gene="pavA"
                     /locus_tag="VQ543_001048"
     CDS             complement(19678..21333)
                     /gene="pavA"
                     /locus_tag="VQ543_001048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_094859469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rqc2 family fibronectin-binding protein PavA"
                     /protein_id="HET2611780.1"
                     /translation="MSFDGFFLHHIVEELRSELVNGRIQKINQPFEQELVLQIRSNRQ
                     SHRLLLSAHPVFGRIQLTQTTFENPAQPSTFIMVLRKYLQGALIESIEQVENDRIVEI
                     TVSNKNEIGDHIQATLIIEIMGKHSNILLVDKSSHKILEVIKHVGFSQNSYRTLLPGS
                     TYIAPPSTKSLNPFTIKDEKLFEILQTQELTAKNLQSLFQGLGRDTANELERILVSEK
                     LSAFRNFFNQETKPCLTETSFSPVPFANQVGEPLANLSDLLDTYYKDKAERDRVKQQA
                     SELIRRVENELQKNRHKLKKQEKELLATDNAEEFRQKGELLTTFLHQVPNDQDQVILD
                     NYYTNQPIMIALDKALTPNQNAQRYFKRYQKLKEAVKYLTDLIEETKATILYLESVET
                     VLNQAGLEEIAEIREELIQTGFIRRRQREKIQKRKKLEQYLASDGKTIIYVGRNNLQN
                     EELTFKMARKEELWFHAKDIPGSHVVISGNLDPSDAVKTDAAELAAYFSQGRLSNLVQ
                     VDMIEVKKLNKPTGGKPGFVTYTGQKTLRVTPDSKKIASMKKS"
     gene            21438..21935
                     /gene="ybeY"
                     /locus_tag="VQ543_001049"
     CDS             21438..21935
                     /gene="ybeY"
                     /locus_tag="VQ543_001049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018380869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA maturation RNase YbeY"
                     /protein_id="HET2611781.1"
                     /translation="MYIEMVDETGQVSKEMLQQTQEILEFAAQKLGKEDKEMAVTFVT
                     NERSHELNLGYRDTDRPTDVISLEYKPELEIAFDEEDLLENPELAEMMSEFDAYIGEL
                     FISIDKAHEQAEEYGHSFEREMGFLAVHGFLHINGYDHYTPEEEAEMFGLQEEILTAY
                     GLTRQ"
     gene            21916..22311
                     /locus_tag="VQ543_001050"
     CDS             21916..22311
                     /locus_tag="VQ543_001050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000378166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HET2611782.1"
                     /translation="MDSQDNKRKWKNRDLISSLEFAITGIFTAIKEERNMRKHAVTAL
                     VVILAGFGFQVSRIEWLFLLLSIFLVVAFEIINSAIENVVDLASHYHFSMLAKNAKDM
                     AAGAVLVVSLFAALTGALIFLPRIWDLLF"
     gene            22328..23227
                     /gene="era"
                     /locus_tag="VQ543_001051"
     CDS             22328..23227
                     /gene="era"
                     /locus_tag="VQ543_001051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase Era"
                     /protein_id="HET2611783.1"
                     /translation="MTFKSGFVAILGRPNVGKSTFLNHVMGQKIAIMSDKAQTTRNKI
                     MGIYTTDKEQIVFIDTPGIHKPKTALGDFMVESAYSTLREVDTVLFMVPADEARGKGD
                     DMIIERLKAAKVPVILVVNKIDKVHPDQLLSQIDDFRNQMDFKEIVPISALQGNNVSR
                     LVDILSENLDEGFQYFPSDQITDHPDRFLVSEMVREKVLHLTREEIPHSVAVVVDSMK
                     RDEETDKVHIRATIMVERDSQKGIIIGKGGAMLKKIGSMARRDIELMLGDKVFLETWV
                     KVKKNWRDKKLDLADFGYNEREY"
     gene            23276..24100
                     /gene="mutM"
                     /locus_tag="VQ543_001052"
     CDS             23276..24100
                     /gene="mutM"
                     /locus_tag="VQ543_001052"
                     /EC_number="3.2.2.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001114577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-formamidopyrimidine glycosylase"
                     /protein_id="HET2611784.1"
                     /translation="MPELPEVETVCRCLEKLIIGKKISSIEIRYPKMIKTDLEEFQRE
                     LPSQIIESMGRRGKYLLFYLTDKVLISHLRMEGKYFYYPDQGPERKHAHVFFHFEDGG
                     TLVYEDVRKFGTMELLVPDLLDAYFISKKLGPEPSEQDFDLQVFQSALAKSKKPIKSH
                     LLDQTLVAGLGNIYVDEVLWRAQVHPARSSQTLTAEEATAIHDQTIAVLSQAVEKGGS
                     TIRTYTNAFGEDGSMQDFHQVYDKTGQGCVRCGTIIEKIQLGGRGTHFCPNCQRRD"
     gene            24100..24705
                     /locus_tag="VQ543_001053"
     CDS             24100..24705
                     /locus_tag="VQ543_001053"
                     /EC_number="2.7.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dephospho-CoA kinase"
                     /protein_id="HET2611785.1"
                     /translation="MGKIIGITGGIASGKSTVTNFLRQQGFQVVDADAVVHQLQKPGG
                     RLFEALVQHFWQEIILENGELNRPLLASLIFSNPDEREWSKQIQGEIIREELATLREQ
                     LAQTEEIFFMDIPLLFEQDYSDWFAETWLVYVDRDAQVERLMKRDQLSKDEAESRLAA
                     QWPLEKKKDLASQVLDNNGNQNQLLNQVHILLEGGRQDDRD"
     gene            24692..25891
                     /locus_tag="VQ543_001054"
     CDS             24692..25891
                     /locus_tag="VQ543_001054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HET2611786.1"
                     /translation="MTEINWKDNLRIAWFGNFLTGASISLVVPFMPIFVENLGVGSEQ
                     VAFYAGLAISVSAISAALFSPIWGILADKYGRKPMMIRAGLAMTITMGGLAFVPNIYW
                     LIFLRLLNGVFAGFVPNATALIASQVPKEKSGSALGTLSTGVVAGTLTGPFIGGFIAE
                     LFGIRTVFLLVGSFLFLAAILTICFIKEDFQPVAKEKAIPTKELFTSVKYPYLLLNLF
                     LTSFVIQFSAQSIGPILALYVRDLGQTENLLFVSGLIVSSMGFSSMMSAGVMGKLGDK
                     VGNHRLLVVAQFYSVIIYLLCANASSPLQLGLYRFLFGLGTGALIPGVNALLSKMTPK
                     AGISRVFAFNQVFFYLGGVVGPMAGSAVAGQFGYHAVFYATSLCVAFSCLFNLIQFRT
                     LLKVKEI"
     gene            25891..26040
                     /gene="rpmG"
                     /locus_tag="VQ543_001055"
     CDS             25891..26040
                     /gene="rpmG"
                     /locus_tag="VQ543_001055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HET2611787.1"
                     /translation="MRVKINLKCSSCGSINYLTSKNSKTHPDKIEVLKYCPKERKVTL
                     HLESK"
     gene            26080..26313
                     /gene="secG"
                     /locus_tag="VQ543_001056"
     CDS             26080..26313
                     /gene="secG"
                     /locus_tag="VQ543_001056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecG"
                     /protein_id="HET2611788.1"
                     /translation="MYNLLLTILLVLSVVIVIAIFMQPTKNQSSNVFDASSGDLFERS
                     KARGFEAVMQRLTGILVFFWLAIALALTVLSSR"
     gene            26415..28769
                     /gene="rnr"
                     /locus_tag="VQ543_001057"
     CDS             26415..28769
                     /gene="rnr"
                     /locus_tag="VQ543_001057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000653285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease R"
                     /protein_id="HET2611789.1"
                     /translation="MKDRIKEYLQDKGKVTVNDLAQALGKDSSKDFRELIKTLSLMER
                     KHQIRFEEDGSLTLEIKKKHEITLKGIFHAHKNGFGFVSLEGEEDDLFVGKNDVNYAI
                     DGDTVEVVIKKVADRNKGTAAEAKIIDILEHSLTTVVGQIVLDQEKPKYAGYIRSKNQ
                     KISQPIYVKKPALKLEGTEVLKVFIDKYPSKKHDFFVASVLDVVGHSTDVGIDVLEVL
                     ESMDIVSEFPEAVVKEAESVPDAPSQKDMEGRLDLRDEITFTIDGADAKDLDDAVHIK
                     ALKNGNLELGVHIADVSYYVTEGSALDKEALNRATSVYVTDRVVPMLPERLSNGICSL
                     NPQVDRLTQSAIMEIDKHGRVVNYTITQTVIKTSFRMTYSDVNDILAGDEEKRKEYHK
                     IVSSIELMAKLHETLENMRVKRGALNFDTNEAKILVDKQGKPVDIVLRQRGIAERMIE
                     SFMLMANETVAEHFSKLDLPFIYRIHEEPKAEKVQKFIDYASSFGLRIYGTASEISQE
                     ALQDIMRAVEGEPYADVLSMMLLRSMQQARYSEHNHGHYGLAADYYTHFTSPIRRYPD
                     LLVHRMIRDYGRSKEIAEHFEQVIPEIATQSSNRERRAIEAEREVEAMKKAEYMEEYV
                     GEEYDAVVSSIVKFGLFVELPNTVEGLIHITNLPEFYHFNERDLTLRGEKSGITFRVG
                     QQIRIRVERADKMTGEIDFSFVPSEFDVIEKGLKQSSHSGRGRGSNRRSDKKEDKRKS
                     GRSNDKRKHSQKDKKKKGKKPFYKEVAKKGAKHGKGRGKGRRTK"
     gene            28732..29199
                     /gene="smpB"
                     /locus_tag="VQ543_001058"
     CDS             28732..29199
                     /gene="smpB"
                     /locus_tag="VQ543_001058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SsrA-binding protein SmpB"
                     /protein_id="HET2611790.1"
                     /translation="MAKGEGKVVAQNKKARHDYTIVDTLEAGMVLTGTEIKSVRAARI
                     NLKDGFAQVKNGEVWLSNVHIAPYEEGNIWNQEPERRRKLLLHKKQIQKLEQETKGTG
                     MTLVPLKVYIKDGYAKLLLGLAKGKHDYDKRESIKRREQNRDIARVMKAVNQR"
     gene            29215..30075
                     /gene="tehB"
                     /locus_tag="VQ543_001059"
     CDS             29215..30075
                     /gene="tehB"
                     /locus_tag="VQ543_001059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000413836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent methyltransferase TehB"
                     /protein_id="HET2611791.1"
                     /translation="MEKLVAYKRMPLWNKQTMPEDVQQKHNTKVGTWGKITVLKGALK
                     FIELTEEGEVLAEHLFEAGADNPMAQPQAWHRVEAATDDVEWYLEFYCKPEDYFAKKY
                     NTNPVHSEVLEAMQTVKQGKALDLGCGQGRNSLFLAQQDFDVTAVDQNGLALEILQSI
                     VEQEDLDMPVGLYDINSASIEQEYDFIVSTVVLMFLQADRIPAIIQNMQEKTSVGGYN
                     LIVCAMDTEDYPCSVNFPFTFKEGELADYYKDWELVKYNENPGHLHRRDENGNRIQLR
                     FATLLAKKIK"
     gene            30148..>30742
                     /gene="coiA"
                     /locus_tag="VQ543_001060"
     CDS             30148..>30742
                     /gene="coiA"
                     /locus_tag="VQ543_001060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000495911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein CoiA"
                     /protein_id="HET2611792.1"
                     /translation="MFVARDARGELVNVLEDKLEKQAYTCPACGGQLHLRQGPSVRTH
                     FAHKSLKDCDFFFENESPEHLANKESLYHWLKKETKVQLEYPLSELKQIADVFVNGNL
                     ALEVQCSPLPQKVLKERSEGYRSQGYQVLWLLGQKLWLKERLTRLQQGFLYFSQNMGF
                     YVWELDKEKQVLRLKYLIYQDLRGKLHYQIKEFSYGQG"
BASE COUNT         9132 a         5689 c         7052 g         8869 t
ORIGIN      
        1 tggaaagtaa gaaatattgg agctgaggcg attagaagaa attgtgagcg tggtgctatt
       61 ttttcaggta aaataaaaca tcacgaagat tctcagttta aaggagacca ctatgttgaa
      121 tgttatgctg ttttagataa tacggttata gcaagagata gaataacagt ccctatcgat
      181 ccgttatgtg gaaaagattt tatagagtag catataattg attcttaact ggaatactct
      241 ctatctcttt acatcaagaa aatgactaaa cagggaagtt tgccttcttc cctttttttg
      301 ttatactagt agaagaaaaa aatagaaaga tttgtgggag tgaaaaagtc cgggggactt
      361 tttcagcttg agccaagaaa ttcgagagcg aggaaagtcc gggggacttt ttcagcctga
      421 gccaagaaat tcgagagcga agtaagtcca atggactttt tcagcctgag ccaagaaact
      481 cgaaagctcg taagtctgat tggctttttc aatgtgaatc ttaacttcac actcccaaag
      541 aggtattagt gtcgtgtctc aatcttatat caatgttatc ggtgctggtt tggcaggttc
      601 tgaagcagct taccaaatcg cagagcgtgg tattccagtt aaactatatg aaatgcgtgg
      661 tgtcaagtcg actccccagc ataaaacaga caattttgct gagttggttt gttccaattc
      721 tttgcgtggg gatgctttga caaatgcagt tggtcttctc aaggaagaaa tgcgtcgctt
      781 gggttctgtt atcttggaat ctgctgaggc tacacgtgtt cctgcaggtg gtgcccttgc
      841 agtggaccgt gatggtttct ctcaaatggt gaccgaaaaa gttgccaacc accccttgat
      901 tgaagtggtt cgtgatgaaa ttacagaatt gccgacagat gttattacgg ttatcgctac
      961 tggtcctttg acaagtgatg ccttggctga aaagattcat gcccttaatg acggtgatgg
     1021 tttttatttc tacgatgcgg cagcgcctat tatcgatgtc aacactatcg atatgagcaa
     1081 ggtctacctc aaatcacgtt atgataaggg agaagcggcc tacctcaatg cccctatgac
     1141 caagcaagaa tttatggatt tccatgaagc tttggtcaat gcagaagaag caccgcttaa
     1201 ttcttttgaa aaagaaaagt actttgaagg ctgtatgcct atcgaagtca tggccaaacg
     1261 tggcattaaa actatgcttt atggccctat gaagccagtc ggtcttgagt acccagacga
     1321 ctatacagga cctcgtgatg gagaatttaa aacaccttat gcggttgtgc aacttcgtca
     1381 ggacaatgca gctggtagcc tctacaatat tgttggtttc cagacccacc tcaaatgggg
     1441 agaacaaaag cgtatcttcc aaatgattcc gggtcttgaa aatgcagagt ttgtccgtta
     1501 tggtgtcatg catcgcaatt cttacatgga ttcaccaaat cttcttgagc agacttaccg
     1561 ttctaagaaa caaccaaatc tcttctttgc tggtcagatg acgggggtgg aaggctatgt
     1621 tgagtcggcg gcttcaggct tagttgcggg aattaacgca gctcgtctct tcaaggaaga
     1681 aagcgaggct attttccccg agacgacagc gattggaagc ttagctcatt acattaccca
     1741 tgccgacagc aaacatttcc aaccaatgaa tgtcaatttt gggatcatca aggagttgga
     1801 aggcgagcgt atccgtgata agaaggctcg ttatgaaaaa attgcagagc gtgcccttgc
     1861 cgacttagag gaatttttga ctgtctaatt tttttgaaag aattgctcat gatactataa
     1921 aaatcttaga aattgtgata aaataggtag gatgaaagaa ggagagtgaa aatggcgaat
     1981 cccaagtata aacgtatttt aatcaagtta tcaggtgaag cccttgccgg tgaacgtggc
     2041 gtagggattg atatccaaac agttcaaaca atcgcaaaag agattcaaga agttcatagc
     2101 ttaggtatcg aaattgccct tgttattggt ggaggaaatc tctggcgtgg agaacctgca
     2161 gcagaagcag gtatggaccg tgttcaggca gattacactg gaatgcttgg gactgttatg
     2221 aatgctcttg tgatggcaga ttcattgcaa caagttgggg ttgatacgcg tgtacaaaca
     2281 gctattgcta tgcaacaagt ggcagagcct tatgtccgtg gacgtgccct tcgtcacctt
     2341 gaaaaaggcc gtatcgttat ctttggtgct ggaattggtt caccatactt ctcgacagat
     2401 acaacagcgg cccttcgtgc agctgaaatc gaagcggatg ccatcctcat ggctaaaaat
     2461 ggtgtcgatg gtgtttacaa tgccgatcct aagaaagata agacagctgt taagtttgaa
     2521 gaattgaccc accgtgacgt tatcaataaa ggtcttcgta tcatggactc aacagcttca
     2581 accctctcaa tggacaacga cattgacttg gttgtcttca acatgaacca atcaggcaac
     2641 atcaaacgtg tcgtatttgg tgaaaatatc ggaacaacag tttcaaataa tatcgaagaa
     2701 aaggaataag aaagaatatg gctaacgcaa ttattgaaaa agctaaagag agaatgaccc
     2761 agtctcacca atcacttgct cgtgaatttg gtggtatccg tgctggtcgt gccaatgcaa
     2821 gcttgcttga ccgtatacat gtagaatact atggagttga aactcctctt aaccaaatcg
     2881 cttcaattac gattccagaa gcgcgtgttt tgttggtaac accatttgac aagtcttcat
     2941 tgaaagacat cgaacgtgcc ttgaacgctt ctgatcttgg tatcacacca gctaatgacg
     3001 gttctgtgat tcgcttggtt gtcccagctc ttacagaaga gactcgtcgt gaccttgcta
     3061 aagaagtgaa gaaggtcggc gaaaatgcta aagtggctgt ccgcaatatc cgtcgcgatg
     3121 ctatggacga agctaagaaa caagaaaaag caaaagaaat cactgaagac gaattgaaga
     3181 ctcttgaaaa agacattcaa aaagtaacag acgatgctgt taaacacatc gacgatatga
     3241 ctgccaacaa agagaaagaa cttttggaag tctaaaaata aacagaaaaa ctcagttggc
     3301 attgctggct gagttttatt cgaaagaagg aaatatgaat acaaatcttg caagttttat
     3361 cgttggactg atcatcgatg aaaacgaccg tttttacttt gtgcaaaagg atggtcaaac
     3421 ctatgctctt gctaaggaag aaggccaaca tacagtaggg gatacggtca aaggttttgc
     3481 atacacggat atgaagcaaa aactccgcct gacaagctta gaagtgactg ccactcagga
     3541 ccaatttggt tggggacgtg tcacagaggt tcgtaaggac ttgggtgtct ttgtggatac
     3601 aggccttcct gacaaggaaa tcgttgtgtc actcgatatt ctccctgagc tcaaggaact
     3661 ctggcctaag aagggcgacc aactctacat ccgtcttgaa gtggataaga aagaccgtat
     3721 ctggggtctc ttggcttatc aagaagactt ccaacgtctt gctcgtcctg cctacaacaa
     3781 catgcagaac caaaactggc cagccattgt ttaccgtctc aagctatcag gaacttttgt
     3841 ttacctacca gaaaataata tgcttggttt tattcatcct agcgagcgtt acgcagagcc
     3901 acgtttgggg caagtattag atgcgcgcgt tattggtttc cgtgaagtgg accgcacttt
     3961 gaacctctcc ctcaaaccac gctcctttga aatgttggaa aacgatgctc agatgatttt
     4021 gacttatttg gaaagcaatg gcggtttcat gaccttaaat gacaagtcat ctccagacga
     4081 catcaaggca acctttggca tttctaaagg tcagttcaag aaagctttag gtggtcttat
     4141 gaaggctggt aaaatcaagc aggaccagtt tggtacagag ttgatttagg gaggcttatg
     4201 agaaaatcat tttacacttg gctcatgacc gagcgcaatc ctaaaagtaa caatcccaaa
     4261 gcaattttgg cagacctcgc ttttgaagag gcagcttttc caaaacatac agatgatttt
     4321 gatgaggtca gtcgcttttt ggaggagcat gccagtttct cttttaacct aggagatttt
     4381 gacagcattt ggcaggaata tctagaacac tagcatttat tcattgggtt tgggctagta
     4441 atttctccat ccctctgcta taataaaaag aaataaaagg attagagagg ttctttattt
     4501 gaaggaacat tcaatagaca ttcaactgag tcatccagat gacctgtttc atctttttgg
     4561 ttccaatgaa cgccatcttc gtttgatgga agaagagctt gatgttgtga ttcatgctcg
     4621 tacggagatt gtccaggttt tgggagaaga gtctgcttgc gaggaagccc gtcaggttat
     4681 tcaagctctc atggccttgg taaatcgtgg gatgaccgtt ggtacgccag atgtagtgac
     4741 ggctattagt atggtcaaaa atgatgaaat tgacaagttt gtcgcccttt acgaagaaga
     4801 aatcatcaag gataatactg ggaagcctat ccgcgtcaaa accttaggtc aaaaacttta
     4861 tgtggacagt gtcaaacagc atgatgtgac ctttggaatt gggccagcag gtacagggaa
     4921 gaccttcctt gcagtgacct tggcagtgac tgcccttaaa cgtgggcaag tcaagcgaat
     4981 tatcctaact cgtccagcgg tggaagcggg agagagtctt ggatttcttc cgggtgatct
     5041 taaggagaag gtggatcctt accttcgtcc tgtttacgat gccttgtatc aaattcttgg
     5101 gaaagaccaa acgactcgtc tcatggagcg tgaaattatc gaaattgcgc cccttgccta
     5161 tatgcgtggc cggaccttgg atgatgcctt tgtcattctc gatgaggcgc aaaacacgac
     5221 catcatgcag atgaagatgt tcttgacgcg tttaggcttt cattctaaga tgattgtcaa
     5281 tggagatatc agtcagattg acctgccacg taatgtcaag tccggtttga ttgatgctca
     5341 agagaaactc aagaacatcc atcagattga ctttgttcat ttttcagcca aggatgtggt
     5401 tcgccatcca gttgtcgctc agattatccg agcctatgaa tattctactg aagttgcaca
     5461 cgactgattt tgaggaagtt cgcctgcaaa agaatatact tttgagagag gaaaatccag
     5521 ttgtataggc taaaggtttg agacaacgat taggcacgat ggaaagaact tttatgtggc
     5581 tgatgacgat cagtgcatct tcctgtgtca taatcacagg gcacaagaaa gtaggaattt
     5641 gaaaagatga ttgaccaact atctaagtat tacagttgta ggatactaac tgaaaaggat
     5701 attccaagta ttttatcttt atatgaaagt aatcctctgt attttcagca ttgtccacca
     5761 gagccaaatt ttgcaactgt aaaagaggac atgctttgtc tacctgaagg taaagctaag
     5821 gctgataagt tttttgttgg attttggaat ggctctgacc ttgtggctgt tatggatttt
     5881 gtctatgcat atcctgatga ggagactgtt tttattggtt tgtttatggt tgatcaagcc
     5941 tatcagagga aagggattgg tagtcatatt gtgacagaag cactagctta ttttgctaag
     6001 aactttcgaa aggcacgttt ggcttatgtt aagggaaatc cgcaatctca gcatttttgg
     6061 gaaaagcagg gctttaaatc aattggatgc gaggttaagc aagaactcta tacggttgtt
     6121 atcgctgaac agagcctaga agattagaaa tggcatcaag taagaactat ttggaatttg
     6181 ttttggaaca attatcagga ttagatgatg tgacttaccg ttccatgatt ggggagtata
     6241 ttctttactt ccgcggcaag attattggcg gcatttatga cgatcgcttt ttagttaaac
     6301 ccgtgcaagc agtcttagat aagattgacc aatcttcttt tgagtttcca tacaaaggtg
     6361 ccaaagaaat gatttgagtg gaagaacttg ataataagat gtttctataa gacctgattt
     6421 tagctatgta taaccaactg ccaacgccca aacctaaaaa gaaaaagcaa gggtgaacga
     6481 agtaaaaaag aagtctgcta aggccctgtc tttgcacggg taaaatttta tatataaaaa
     6541 gaagctggga ctaaagagct cagcttcctt tggtttatat aattgtcatt acaagacgaa
     6601 gtggttgggc gaaactctgt tgactttatt caatttagag tttcttatgc acaattgagt
     6661 ctggaacgaa agtctccagt tgcaaagtat acagtacaat aaaccaacga tgtaatagct
     6721 gatgacacaa agcacagtgg gtaggacttg cgaagtcacc cttttctttt caaaatttat
     6781 actaaatcat tgatatcagt gtagtcacga ttaagtcctt gagcaactgg taggctagtc
     6841 aagtaacctt gataagtggt cacaccttga cgcaagcctt catcttcaga gattgcttgt
     6901 gcgaatcctt tgccagccaa agcttcgata taaggaagag tgacattggt tagggcgatg
     6961 gttgaagtgc gggcaaccgc accagggata ttggcaacgg catagtggag aacaccgtgt
     7021 ttttcataga cgggttcatc gtgcgttgtc acacggtcag ctgtttcgat aacgccacct
     7081 tggtcaacag caacgtcaac gatacagagc ctggacgcat ttgtttgacc atctcatctg
     7141 tcaccaattc cggtgctttt gcaccaggga tgagaatggc tccaatcacc acatcagcat
     7201 ctctcacact tgcttcaatg ttgaatgaat tagatataat agtttgaatt tgacttccaa
     7261 agacttcttc tagaactgag agacgcttgg cactaatatc taaaatagtc acttgagcac
     7321 caagaccaag ggcgatgcgg gcagcatgtg taccgacgac accatcaccg atgatagtta
     7381 cttttccttt tggaacacct ggtacaccac caagtagaac accagagcca ccagcttgct
     7441 tagtaaggaa gtgagctccg atttgaacag ccatacgacc tgcaacctca ctcataggaa
     7501 cgaggagcgg tagttgtcct tgattgtcac gaacagtttc ataggcaatt cctgttgttt
     7561 ttgctgctaa catagcatct gctaattctg gagcagcggc catgtgcaag taggtgaaga
     7621 gaagaagatc gtcgcgcaag taaccgtatt cagaacttaa aggttctttt actttcacaa
     7681 ccaactctgc tgcccaagct tcaccagcag tagcgacaat ctcagctcct tgcttttgat
     7741 agtcagcatc agtaaagcca gaaccgagac cagcatttgt ttcgataagg acacgatgac
     7801 cacgactaac taagctatga acacctgcag gtgtgagggc gacacggttt tcgttatttt
     7861 taatttcttt tgggattccg attaacattg agataaccta cctttcaatt gacggtcttg
     7921 ttttggttgt cacattccag ttcataaatc aaaaatgtga cggtttcatt gtatatgaaa
     7981 ccgcttcaaa aatcaagaaa aacttgtcat ccaaattttt ttatgctaga ctagtgaaaa
     8041 tcaagctcta atggagggaa aagtatggaa tcaatatttg tgaaatttgc ccagtatccg
     8101 tctatagaaa cggagcgttt attgcttaga cctgtaactt tggatgatgc ggaagcaatg
     8161 tttgactatg cctcggacaa gggtaataca cgttacactt ttccaaccaa tcaaagcttg
     8221 gaagaaacca agaataacat tgctcagttc tacttggcta atcccttggg acgttggggg
     8281 attgaattaa aagataacgg caagtttatc ggaactattg acttacacaa gattgatcct
     8341 gttcttaaga aggcagctat tggctacatt atcaataaaa agtattggaa tcaaggatta
     8401 acgacagaag ccaatcgtgc tgtgattgag ctagcttttg agaagatagg gatgaataag
     8461 ttgactgccc ttcacgataa ggctaatccc gcgtcaggaa aggtcatgga gaaatcaggc
     8521 atgcgttttt cccatgcaga accatatgct tgtatggacc agcatgaaaa aggccgaatc
     8581 gtgacaagag ttcattatgt cttgaccaag gaagactatt ttgcaaataa ataagcagtt
     8641 gaaaagaaat ttttcgactg ttttttcttc ctcttacgaa taatctaaga gaggagaaaa
     8701 tatggaagca attatcgaga aaatcaaaga gtataaaatc atcgtcatct gtactggtct
     8761 gggcttgctt gtaggaggat ttttcctgct aaagccagct ccacaaacat ctgtcaaaga
     8821 gacgaatttg caggctgaag ttgcagctgt ttccaaggac tcatcgaccg gaaaggaagt
     8881 gaacaaggaa gagaaggaag aaccagttga acaagatcta atcacagtag atgtcaaagg
     8941 tgctgtcaaa tcgccaggga tttatgactt gcctgtaggt agtcgagtca atgatgctgt
     9001 tcagaaggct ggtggcttga cagagcaagc agacagcaag tcgctcaatc tagctcagaa
     9061 agttagtgat gaggctctgg tttacgttcc tactaaggga gaagaagcag ttagtcaaca
     9121 gactggttcg gggacagctt cttcaacaag caaggaaaag aaggtcaatc tcaacaaggc
     9181 cagtctggaa gaactcaagc aggtcaaggg actgggagga aaacgagctc aggacattat
     9241 tgaccatcgt gaggcaaatg gcaagttcaa gtcagtagac gagctcaaga aggtctctgg
     9301 cattggtgcc aagaccatag aaaaacttaa agactatgtt acagtggatt aagaatttct
     9361 ctattcccct aatttacctg agttttctat tactatggct ttactacgcc attttctcag
     9421 tatcctattt tgctttgttg ggttttgttt ttctgctagt ctgcctcttt atccaatttc
     9481 cttggaaatc agcaggtaaa gttctagtga tttgtggagt ctttggcttc tggtttctgt
     9541 ttcaaacttg gcaacagagt caagtgagtc aaaatttggt ggattctgtt gaaagggtac
     9601 ggattttacc agacactatt aaggttaacg gtgacagtct gtcctttcgt ggtaagtctg
     9661 atggtcgtgc tttccaagtc tattataaac tccagtccga ggaggagaaa gaagcctttc
     9721 aagctttaac tgaccttcat gagataggac tagaagggaa gctttcggag ccagaagggc
     9781 agagaaattt tggtggcttt gactaccaag gctatctgaa gactcaggga atttaccaga
     9841 cactcaatat taaaagaatc cagtcactcc aaaaggttgg cagttgggat ataggtgaaa
     9901 acctgtccag tttacgtcga aaggctgtgg tttggattaa gatgcacttc ccagacccta
     9961 tgcgcaatta catgacagga ctcttgctag gacatctgga caccgatttt gaggagatga
    10021 atgagcttta ttccagttta ggaattattc acctttttgc cttgtcaggt atgcaggtag
    10081 ggtttttcat ggacggattt aagaaactac ttttacgatt gggcttgaca caagaaaagt
    10141 tgaagtggct gacttatccc ttttccctta tctatgcggg actaactgga ttttcagcat
    10201 cggttattcg cagtctcttg caaaagctac tggctcaaca tggggttaag ggcttggata
    10261 attttgcctt gacggtgctt gtcctcttta ttgtcatgcc aaactttttc ttgacagcag
    10321 gaggagtctt gtcctgtgct tatgctttta tcctgaccat gaccagcaaa gaaggggagg
    10381 ggctcaaggc tgttactagt gaaagtctag tcatctcctt gggcatattg cccattctat
    10441 ccttctattt tgcggaattt caaccttggt ctatcctttt gacctttgtc ttttcctttc
    10501 tttttgactt ggtcttctta ccgctcttgt ctatcttatt tgtcctttcc tttctctatc
    10561 cagtcattca gctgaacttt atctttgaat ggttagaggg cattattcgc ttggtctcgc
    10621 aggtggcaag tagaccgctt gtctttggac aacccaatga atggctttta atcctattgt
    10681 taatttcttt ggctttggtc tatgatttga ggaaaaacat taaaaagcta acggtattgt
    10741 gcttattgat tacagggctc tttctcctga ccaagcatcc actggaaaat gaaatcacca
    10801 tgctggatgt ggggcaagga gaaagtattt tcctacggga tgtaactggg aaaaccattc
    10861 tcatagatgt aggtggtaag gcagaatctt ataagaaaat caaaaaatgg caagaaaaga
    10921 tgacgaccag caatgcccag cgaagcttga taccctatct caaaagtcga ggagtagcta
    10981 agattgacca gctaattttg actaacacgg acaaggagca tgttggagat ttgtcagaga
    11041 tgaccaaggc tttccatgta ggggagattc tagtatcaaa agacagtctg aaacagaagg
    11101 aatttgtggc agaactacag gcgactcaaa caaaggtgcg tagtatgata gtaggggaga
    11161 acttacccat ttttggaagt cagttagaag ttctatctcc aaggaaaatg ggagatggag
    11221 gacacgatga taccctagtt ctgtatggga aattcttgga taagcaattt ctcttcacgg
    11281 gaaatttgga ggagaaagga gagaaggact tgctgaagca ctatccagac ttgaaagtaa
    11341 atgttttgaa agctagccaa catggcaata aaaaatcatc aagtccagcc tttctagaaa
    11401 aactcaaacc agagcttact cttatctcag ttggaaagag caatcgaatg aaactccccc
    11461 atcaggaaac attgacacga ctggaaggta tcaatagcaa agtttatcga actgaccagc
    11521 aaggagctat acgttttaag gggttggata gttggaaaat cgaaagtgtt cgataggaag
    11581 gataaatgtt gtagattagt gaaataaact aaaaatttgt tgcataataa tgataaaaac
    11641 ggcataatga aaacgtattc aatattgagg atataaaatc attaaaaatc agcaaaagtt
    11701 gttttagtta gttagtttat aatctattgg tcttcttcag tccagtgtat ctgctgtgac
    11761 agtcactaaa agttacaagt atgattggaa tacggttttg gaatatagta ccaactatca
    11821 cgaccatcag tatgcttgga ttccggaatg gtctcgttat tacagctatt ctgagtataa
    11881 agttggcgga ggctggaact acgctcgtta tgaggtcata aactactata ctggaggtta
    11941 ttaatcctta aagagtgaga aaaggagggc tggatatgtt aaatcttact catgttacct
    12001 taaaaacgcg acaagtcatc ttgcaagatg cggattttac ctttaaaaag ggtaggattt
    12061 atggccttct tgctatcaat ggctcgggaa agacgacact attccgagct atgagcaagt
    12121 tgcttcccct tagtagtgga cacatcgcag ttcctccttc tttgttttat tatgagagcg
    12181 ttgaatggct ggatggaaac ttaagtggga tggactacct tcgtctcata aaaaacatct
    12241 ggaagtcaga cctaaacttg agagatgaaa tcgcctactg ggaaatggct gactatatca
    12301 gtcttcccat ccgcaagtat tccttaggga tgaagcaacg cttggtgatt gctatgtatt
    12361 ttctcagtca ggccaaatgc tggctcatgg atgagattac aaatggctta gacgagtatt
    12421 atcgacagaa gttttttgat aggctagcac aaatcgatag acaagaacag ctggttcttt
    12481 taagttccca ctataaggaa gagttggttg atatctgcga tagagtagta accattcatc
    12541 aggggcagat agaagaggtt tagtttatga aagatgttag tctattttta ttgaaaaaag
    12601 ttttcaaaag tcgtttaaac tggattatct tagctttatt tgtatctgta ctcggtgtta
    12661 ccttttattt aaatagtcag actgcaaact cacacagctt ggagagcagg ttggaaagtc
    12721 gcattgcagc caacgagagg gctatcaatg aaaatgaaga gaaactctcc caaatgtctg
    12781 ataccagctc ggaggaatac cagtttgcta aaaataattt agacgtgcaa aaaaatcttt
    12841 tgacgcgaaa gacagaaatt ctaactttac taaaagaagg gcgctggaaa gaagcctact
    12901 atctgcagtg gaaagatgaa gagaagaatt atgaatttgt atcaaatgac ccgactgcta
    12961 gctctggctt aaaaatgggg gttgaccgcg aacggaagat ttaccaagcc ctgtatccct
    13021 tgaacataaa agcacatact ttggagtttc cgacccacgg gattgatcag attgtctgga
    13081 ttttagaggt tatcatccca agcttgtttg tggttgcgat tatttttatg ctaacacaac
    13141 tatttgcaga aagatatcaa aatcatctgg acacagctca cttatatcct gtttcaaaag
    13201 tgacatttgc aatatcctct cttggagttg gagtgggata tgtaactgtg ctgtttatcg
    13261 gaatctgtgg cttttctttt ctagtgggaa gtctgataag tggttttgga cagttagatt
    13321 atccctaccc aatttatagc ttagtgaatc aagaagtaac tattgggaaa atacaagatg
    13381 tattatttcc tggcttgctc ttagctttct tagcctttat cgtcattgtg gaagttgtgt
    13441 acttgattgc ttactttttc aagcaaaaaa tgcctgtcct ctttctttca ctcattggga
    13501 ttgttggctt attgtttggc atccaaacaa ttcagcctct tcaaaggatt gcacatctga
    13561 ttccctttac ttacttgcgt tcagtggaga ttttatctgg aagattacct aagcagattg
    13621 ataatgtcga tctaaattgg agcatgggaa tggtcttact tccttgcctg attatctttt
    13681 tgctattggg aattctattt attgaaagat ggggaagttc acagaaaaaa agaatttttt
    13741 aatagattct agctttccta taggtaggga aaataagtaa aaactaacat agagagggaa
    13801 tcaacttgat tctctctttt tgattcgaaa accaaaccaa aatacaaaca caaacttttc
    13861 aaaaaataac tttttatctt gacaagagct agaaaacttg gtatcatata aaagttgaga
    13921 aaagcagaag tgagagcttc tcgccttgtg acattaagtt gcctggccct acggatgaaa
    13981 agtttcgaag aaacgctatc ataacgtgcg ggcttgtata tttacgagtc cgctattgtt
    14041 tttctctaat aaaacaaaag aggtgaaaac catagcaaag caagacttat tcatcaatga
    14101 tgagattcgt gtacgtgaag ttcgcttgat tggtcttgaa ggagaacagc taggcatcaa
    14161 gccactcagt gaagcgcaag ctttggctga taacgctaat gttgacctag tattgattca
    14221 accccaagcc aaaccgcctg ttgcaaaaat tatggactac ggtaagttca aatttgagta
    14281 ccagaagaag caaaaagaac aacgtaaaaa acaaagcgtt gttactgtga aagaagttcg
    14341 tctaagtcca actattgaca agggtgactt tgatacaaaa cttcgtaatg cacgtaagtt
    14401 ccttgaaaaa ggaaataaag ttaaggtatc tattcgcttt aagggtcgta tgattaccca
    14461 taaagagatt ggtgcaaaag ttttagccga gtttgctgaa gcaactcaag atattgccat
    14521 catcgaacaa cgtgctaaaa tggatggacg tcaaatgttc atgcaattgg cgccagcgac
    14581 tgacaaaaaa taattgtcag aaagttaaat aaaggagaaa aaattatgcc aaaacaaaaa
    14641 acacaccgcg catcagctaa acgtttcaaa cgtacaggtt ctggtggact taaacgtttc
    14701 cgtgcttaca cttctcaccg tttccacgga aaaactaaga aacaacgtcg tcatcttcgt
    14761 aaagcatcta tggtgcattc aggagattac aaacgtatca aagcaatgct tactcgcttg
    14821 aaataatagc ttgactgtaa gtaaacaatt ctaggaaata tttggaggaa ataaaacatg
    14881 gcacgtgtta aaggtggcgt tgtatcacgc aaacgtcgta aacgtattct taaattagca
    14941 aaaggttact atggagctaa acacatcttg ttccgtactg caaaagaaca agtaatgaac
    15001 tcttactact atgcataccg tgaccgtcgt cagaaaaaac gtgacttccg caaattgtgg
    15061 atcactcgta tcaatgcggc agctcgtatg aacggacttt catactcaca attgatgcat
    15121 ggtttgaaat tggctgagat cgaagttaac cgtaaaatgc ttgctgactt ggctgttaac
    15181 gatgcagtag ctttcacagc tcttgcagat gcagctaaag caaaacttgg taaataacaa
    15241 ctgatgagac tggaacagga ttgtccagtc tttttaaaaa taaaggagaa aaatatggct
    15301 tcaaaaatgc tacacacttg cttacgagta gaaaatcttg aaaaatcaat cgcattttat
    15361 caagatgctt ttggttttaa agaattgcgt cgcagagatt ttccagacca tgccttcacg
    15421 attgtctatc taggtcttga gggtgatgac tatgagttgg agttgactta taactacgat
    15481 cacggtccgt atgtggttgg tgatgggttt gcccatatcg ccctcagtac acctgatctt
    15541 gaggcacttc atcaagaaca cagtgcaaaa ggctatgaag tgactgagcc aaatggtcta
    15601 ccaggaacta caccaaacta ttactttgtc aaagaccctg atggatataa ggtcgaagtc
    15661 attcgtgaaa aataatttcg tgcaagttaa gtagaatatt cgttttttac ttgacttttt
    15721 ttagctgaaa gagtatacta ataaaaattc aacctttaag gggagtccag agagactcac
    15781 aaggtgtcag ataaaagaat agtgcaattt tctagaggag actttttgag tgtgctctct
    15841 tgtgttgtac gattttaact gaggccttgc actagcaagg tcttttcttt atctggtccc
    15901 cttaaaattt aaggaggaaa agttatgaat cccacatgta agaagcgttt gggtgtcatt
    15961 cggttggaaa ccatgaaggt ggttgcacaa gaggaaatcg cgccagcaat ctttgaatta
    16021 gtcctagaag gagaaatggt tgaagccatg cgagcaggcc aatttcttca tctgcgtgta
    16081 ccagacgatg cccatctttt acgtcgtcct atttcaattt cgtctattga caaggcaaac
    16141 aagcagtgtc acctcattta tcggattgag ggagctggga ctgcaatttt ttcaacctta
    16201 agtcagggag acactcttga tgtgatgggg cctcagggaa atggttttga cttgtctgac
    16261 cttgatgagc agaatcaggt tctccttgtt ggtggtggga ttggtgttcc acccttgctt
    16321 gaggtggcca aggaattgca tgaacgtgga gtgaaagtag tgacagtcct cggttttgct
    16381 aataaggatg ctgttatttt gaaaacggaa ttggctcagt atggtcaggt ctttgtaacg
    16441 acagatgatg gttcttatgg catcaaggga aatgtttccg ttgttatcaa tgatttagat
    16501 agtcagtttg atgctgttta ctcgtgtggg gctccaggaa tgatgaagta tatcaatcaa
    16561 acctttgatg atcacccaag agcctattta tctctggaat ctcgtatggc ttgtgggatg
    16621 ggagcttgct atgcctgtgt tctaaaagta ccagaaagcg agacggtcaa ccaacgcgtc
    16681 tgtgaagatg gtcctgtttt ccgcacagga acagttgtat tataaggaga aaattatgac
    16741 tacaaatcga ttacaagtgt ctctacctgg tttggatttg aaaaatccga ttattccagc
    16801 atcaggttgt tttggctttg gacaagagta tgccaagtac tatgatttaa accttttagg
    16861 ttctattatg atcaaggcga caacccttga accacgtttt gggaacccaa ctccaagagt
    16921 agcagagacg cctgctggta tgctcaatgc aattggcttg caaaatcctg gtttagaggt
    16981 tgttttggct gaaaagctac cttggctgga aagagaatat ccaaatcttc ctattattgc
    17041 caatgtagct ggtttttcaa aacaagagta tgcagctgtt tctcatggga tttccaaggc
    17101 aactaatgta aaagctatcg agctcaatat ttcttgtccc aatgttgacc actgtaatca
    17161 tggacttttg attggtcaag atccagattt ggcttatgat gtggtgaaag cagctgtgga
    17221 agcctcagaa gtgccagttt atgtcaaatt aaccccgagt gtgaccgata tcgttactgt
    17281 cgcaaaagct gcagaagatg cgggagcaag tggcttgacc atgatcaata ctctggttgg
    17341 aatgcgcttt gacctcaaaa ccagaaaacc aatcttggcc aatggaacag gtggaatgtc
    17401 aggtccagca gtctttccag tagccctcaa actcatccgc caagtagccc aaacaacaga
    17461 cctgcctatc attggaatgg ggggagtgga ttcggctgaa gctgccctag aaatgtatct
    17521 ggctggggca tctgctatcg gagttggaac agctaacttt accaatcctt atgcctgccc
    17581 tgacatcatc gaaaatttac caaaagtcat ggataaatac ggtattagca gtctggaaga
    17641 actccgtcag gaagtaaaag agtctctgag gtaaactgca atcaatctgt tcttgatttt
    17701 ttattagttt gtaatatgaa tttaggagaa ttttggtaca ataaaataaa taagaacaga
    17761 ggaagaaggt taatgaagaa agtaagattt atttttttag ctctgctatt tttcttagct
    17821 agtccagagg gtgcaatggc tagtgatggt acttggcaag gaaaacagta tctgaaagaa
    17881 gatggcagtc aagcagcgaa tgagtgggtt tttgatactc attatcaatc ttggttctat
    17941 ataaaagcag atgctaacta tgctgaaaat gaatggctaa agcaaggtga cgactatttt
    18001 tacctcaaat ctggtggcta tatggccaaa tcagaatggg tagaagacaa gggagccttt
    18061 tattatcttg accaagatgg aaagatgaaa agaaatgctt gggtaggaac ttcctatgtt
    18121 ggtgcaacag gtgccaaagt aatagaagac tgggtctatg attctcaata cgatgcttgg
    18181 ttttatatca aagcagatgg acagcacgca gagaaagaat ggctccaaat taaagggaag
    18241 gactattatt tcaaatccgg tggttatcta ctaacaagtc agtggattaa tcaagcttat
    18301 gtgaatgcta gtggtgccaa agtacagcaa ggttggcttt ttgacaaaca ataccaatct
    18361 tggttttaca taaaagaaaa tggaaactat gctgataaag aatggatttt cgagaatggt
    18421 cactattatt atctaaaatc tggtggctac atggcagcca atgaatggat ttgggataag
    18481 gaatcttggt tttatctcaa atttgatggg aaaatagctg aaaaagaatg ggtctacgat
    18541 tctcatagtc aagcctggta ctacttcaaa tccggtggtt acatgacagc caatgaatgg
    18601 atttgggata aggaatcttg gttttacctc aagtctgatg gcaaaatggc tgaaaaagaa
    18661 tgggtctacg attctcatag tcaagcctgg tactacttca aatctggtgg ttacatggcg
    18721 aaaaatgaga cagtagatgg ttatcagctt ggaagcgatg gtaaatggct tggaggaaaa
    18781 gctacaaatg aaaatgctgc ttactatcaa gtagtgcctg ttacagccaa tgtttatgat
    18841 tcagatggtg aaaagctttc ctatatatcg caaggtagtg tcgtatggct agataaggat
    18901 agaaaaagtg atgacaagcg cttggctatt actatttctg gtttgtcagg ctatatgaaa
    18961 acagaagatt tacaagcgct agatgctagt aaggacttta tcccttatta tgagagtgat
    19021 ggccaccgtt tttatcacta tgtggctcag aatgctagta tcccagtagc ttctcatctt
    19081 tctgatatgg aagtaggcaa gaaatattat tcggcagatg gcctgcattt tgatggtttt
    19141 aagcttgaga atcccttcct tttcaaagat ttaacagagg ctacaaacta cagtgctgaa
    19201 gaattggata aggtatttag tttgctaaac attaacaata gccttttgga gaacaagggc
    19261 gctactttta aggaagccga agaacattac catatcaatg ctctttatct ccttgcccat
    19321 agtgccctag aaagtaactg gggaagaagt aaaattgcca aagataagaa taatttcttt
    19381 ggcattacag cctatgatac gaccccttac ctttctgcta agacatttga tgatgtggat
    19441 aagggaattt taggtgcaac caagtggatt aaggaaaatt atatcgatag gggaagaact
    19501 ttccttggaa acaaggcttc tggtatgaat gtggaatatg cttcagaccc ttattggggc
    19561 gaaaaaattg ctagtgtgat gatgaaaatc aatgagaagc taggtggcaa agattagtac
    19621 tataagtgaa tatgatttga gtgaatagta agttaaaaat cctgatttca agtaaaatca
    19681 ggattttttc atggatgcaa tttttttgga gtctggtgtg acgcggaggg tcttttgtcc
    19741 tgtgtaagtg acaaagccgg gttttccacc agttggttta ttgagttttt tgacttcaat
    19801 catatctacc tgcaccagat tcgacaggcg cccttgagag aagtaggcag ctaactctgc
    19861 tgcgtctgtc ttgactgcat cagatgggtc aagatttcct gagatgacaa catggcttcc
    19921 aggaatgtcc ttagcatgga accaaagttc ctccttgcgg gccattttaa aggtcaattc
    19981 ctcattttga agattgtttc gtccgacata gatgatggtt ttgccatcgc ttgctagata
    20041 ttgttctagt tttttgcgtt tctggatttt ctcccgttgt cttctgcgga taaaacctgt
    20101 ttgaatcaat tcttcacgga tttcagcgat ttcttccagt ccagcttggt tgaggacggt
    20161 ttctacactt tccagataga gaatagtggc tttggtttct tcaatcaaat cagtcaagta
    20221 tttgacagct tctttgagtt tctgataccg tttaaaatag cgttgggcat tctggttggg
    20281 agtcagagcc ttatcaagcg caatcatgat aggttggttg gtatagtagt tgtctaggat
    20341 aacctggtct tggtcgttag gcacttggtg gaggaaggtt gtcagcaatt ctcctttttg
    20401 acgaaattct tcagcgttgt ctgtcgccag taactctttt tcctgttttt tgagtttgtg
    20461 tcggtttttc tgaagttcat tttcaacacg acgaatcagt tcactggcct gctgtttgac
    20521 gcggtcgcgc tcagccttat ccttatagta ggtgtccaac aaatcagaaa gatttgcaag
    20581 aggctctccc acctgatttg caaaaggaac tggactgaag gaagtctcag tcaagcatgg
    20641 cttggtttct tgattgaaaa aatttcggaa agcggaaagt ttttcactaa ccagtatcct
    20701 ttccaattca tttgccgtat cgcgtcccag accttgaaag aggctttgaa gattttttgc
    20761 tgttagttct tgggtttgca ggatttcaaa gagcttttca tccttgatag taaaaggatt
    20821 gagagatttt gtacttggcg gagcgatata ggtcgatcct ggaagtaagg tgcggtagct
    20881 attttgtgaa aagccgacgt gtttgataac ttcgaggatt ttatgactgc ttttatcgac
    20941 cagtagaata ttactgtgtt tccccataat ttcgataatc aaggtagcct ggatatggtc
    21001 tccaatctcg tttttattgg aaactgtaat ttccacaata cggtcatttt ccacttgctc
    21061 aatcgactca atcagggccc cctgcaaata ctttctcaaa accatgataa aggtagaagg
    21121 ttgggctgga ttttcaaaag tcgtttgggt cagctgaatg cgtccaaaaa ctggatgggc
    21181 agaaaggagc aggcgatggc tttggcgatt gctgcggatt tgcaagacca actcttgttc
    21241 aaaaggctga ttgattttct ggatgcgacc attcactaat tcgcttcgca attcctcaac
    21301 tatgtggtgt aaaaaaaatc cgtcaaatga catcgttctc tccttgtgat tgtattccat
    21361 agtattatat caaaaaggta gaataaaatc atggaaatgt ggtataataa agccaagtaa
    21421 agagaaacga gaagcacatg tatattgaaa tggtagatga aactggtcaa gtttcaaaag
    21481 aaatgttgca acaaacccaa gaaattttgg aatttgcagc ccaaaaatta ggaaaagaag
    21541 acaaggagat ggcagtcact tttgtgacca atgagcgtag tcatgaactt aatctggggt
    21601 accgtgacac cgaccgtccg acagatgtca tcagccttga gtataaacca gaattggaaa
    21661 ttgcctttga cgaagaggat ttgcttgaaa atccagaatt ggcagagatg atgtctgagt
    21721 ttgatgccta tattggggaa ttgttcatct ctatcgataa ggctcatgag caggccgaag
    21781 aatatggtca cagctttgag cgtgagatgg gcttcttggc agtacacggc tttttacata
    21841 ttaacggcta tgatcactat actccggaag aagaagcgga gatgttcggt ttacaagaag
    21901 aaattttgac agcctatgga ctcacaagac aataaacgaa aatggaaaaa tcgtgacctg
    21961 atatccagtt tagaatttgc catcacaggg atttttactg ctatcaagga agaacgcaat
    22021 atgcgaaaac atgcagtgac ggctctagtg gtcatccttg caggttttgg ttttcaggtg
    22081 tcacgaatcg aatggctctt tctcctattg agcattttct tggtggtagc ctttgaaatt
    22141 atcaattctg ctatcgaaaa tgtggtggat ttggccagtc actatcactt ttccatgctg
    22201 gctaaaaatg ccaaggatat ggcggctggc gcggtattag tggtttctct ttttgcagcc
    22261 ttaacaggcg cattgatttt tctcccacga atctgggatt tattatttta aacagtaaga
    22321 ggaaattatg acttttaaat caggctttgt agccatttta ggacgtccca atgttgggaa
    22381 gtcaaccttt ttaaatcacg ttatggggca aaagattgcc atcatgagtg acaaggcgca
    22441 gacaacgcgc aataaaatca tgggaattta cacgactgat aaggagcaaa ttgtctttat
    22501 cgacacacca gggattcaca aacctaaaac agctctcgga gatttcatgg ttgagtctgc
    22561 ctacagtacc cttcgcgaag tggacactgt tcttttcatg gtgcctgctg atgaagcgcg
    22621 tggtaagggg gacgatatga ttatcgagcg tctcaaggct gccaaggttc ctgtgatttt
    22681 ggtggtgaat aaaatcgata aggtccatcc agaccagctc ttgtctcaga ttgatgactt
    22741 ccgtaatcaa atggacttta aggaaattgt tccaatctca gcccttcagg gaaataacgt
    22801 gtctcgtcta gtggatattt tgagtgaaaa tctggatgaa ggtttccaat atttcccgtc
    22861 tgatcaaatc acagaccatc cagaccgttt cttagtttca gaaatggttc gcgagaaagt
    22921 cttgcaccta actcgtgaag agattccgca ttctgtagca gtagttgttg actctatgaa
    22981 acgagacgaa gagacagaca aggttcacat ccgtgcaacc atcatggtcg agcgcgatag
    23041 ccaaaaaggg attatcatcg gtaaaggtgg cgctatgctt aagaaaatcg gtagcatggc
    23101 ccgtcgtgat atcgaactca tgctaggaga caaggtcttc ctagaaacct gggtcaaggt
    23161 caagaaaaac tggcgcgata aaaagctaga tttggctgac tttggctata atgaaagaga
    23221 atactaagta gaggtgggct catgcctgct tcttgttttt acagaaggag gacttatgcc
    23281 tgaattacct gaggttgaaa ccgtttgtcg ttgcttagaa aaattgatta taggaaagaa
    23341 gatttcgagt atagaaattc gctaccccaa gatgattaag acggatttgg aagagtttca
    23401 aagggaattg cctagtcaga ttatcgagtc aatgggacgt cgtggaaaat atttgctttt
    23461 ttatctgaca gacaaggttt tgatttccca tttgcggatg gagggcaagt atttttacta
    23521 tccagaccaa ggacctgaac gcaagcatgc ccatgttttc tttcattttg aagatggtgg
    23581 cacgcttgtt tatgaggatg ttcgcaagtt tggaaccatg gaactcttgg tgcctgacct
    23641 tttagacgcc tactttattt ctaaaaaatt aggtcctgaa ccaagcgaac aagactttga
    23701 tttacaggtc tttcaatctg cccttgccaa gtccaaaaag cctatcaaat cccatctcct
    23761 agaccagacc ttggtagctg gacttggcaa tatctatgtg gatgaggttc tctggcgagc
    23821 tcaggttcat ccagctagat cttcccagac tttgacagca gaagaagcga cagctattca
    23881 tgaccaaacc attgctgttt tgagccaggc tgttgaaaaa ggcggttcca ccattcggac
    23941 ctataccaat gcctttgggg aagatggaag catgcaggat tttcatcagg tctatgataa
    24001 gactggtcaa ggatgtgtac gctgtggtac catcattgag aaaattcaac taggtggacg
    24061 tggaacccac ttttgtccaa actgtcaaag gagggactga tgggaaaaat catcggaatc
    24121 actgggggaa ttgcctctgg taagtcaact gtgacaaatt ttctaagaca gcaaggcttt
    24181 caagtagtgg atgccgacgc agtcgtccac caactacaga aacctggtgg tcgtctgttt
    24241 gaggctctag tacagcactt ttggcaagaa atcattcttg aaaacggaga actcaatcgc
    24301 cctctcctag ctagtctcat cttttcaaat cctgatgaac gagaatggtc taagcaaatt
    24361 caaggggaga ttatccgtga ggaactggct actttgagag aacagttggc tcagacagaa
    24421 gagattttct tcatggatat tcccctactt tttgagcagg actacagcga ttggtttgct
    24481 gagacttggt tggtctatgt ggaccgagat gcccaagtag aacgcttaat gaaaagggac
    24541 cagttgtcca aagatgaagc tgagtctcgt ctggcagccc agtggccttt agaaaaaaag
    24601 aaagatttgg ccagccaggt tcttgataat aatggcaatc agaaccagct tcttaatcaa
    24661 gtgcatatcc ttcttgaggg aggtaggcaa gatgacagag attaactgga aggataatct
    24721 gcgcattgcc tggtttggta attttctgac aggagccagt atttctttgg ttgtaccttt
    24781 tatgcctatc ttcgtggaaa atctaggtgt agggagtgag caagtcgctt tttatgcagg
    24841 cttagcaatt tctgtctctg ctatttccgc ggcgctcttt tctcctattt ggggtattct
    24901 tgctgacaaa tacggccgaa aacccatgat gattcgggca ggtcttgcta tgactatcac
    24961 tatgggaggc ttggcctttg tcccaaatat ctattggtta atctttcttc gtttactaaa
    25021 cggtgtattt gcaggttttg ttcctaatgc aacggcactg atagccagtc aggttccaaa
    25081 ggagaaatca ggctctgcct taggtacttt gtctacaggc gtagttgcag gtactctaac
    25141 tggtcccttt attggtggct ttatcgcaga attatttggc attcgtacag ttttcttact
    25201 ggttggtagt tttctatttt tagctgctat tttgactatt tgctttatca aggaagattt
    25261 tcaaccagta gccaaggaaa aggctattcc aacaaaggaa ttatttacct cggttaaata
    25321 tccctatctt ttgctcaatc tctttttaac cagttttgtc atccaatttt cagctcaatc
    25381 gattggccct attttggctc tttatgtacg cgatttaggg cagacagaga atcttctttt
    25441 tgtctctggt ttgattgtgt ccagtatggg cttttccagc atgatgagtg caggagtcat
    25501 gggcaagcta ggtgacaagg tgggcaatca tcgtctcttg gttgtcgccc agttttattc
    25561 agtcatcatc tatctcctct gtgccaatgc ctctagcccc cttcaactag gactctatcg
    25621 tttcctcttt ggattgggaa ccggtgcctt gattcccggg gttaatgccc tactcagcaa
    25681 aatgactccc aaagccggca tttcgagggt ctttgccttc aatcaggtat tcttttatct
    25741 gggaggtgtt gttggtccca tggcaggttc tgcagtagca ggtcaatttg gctaccatgc
    25801 tgtcttttat gcgacgagcc tttgtgttgc ctttagttgt ctctttaacc tgattcaatt
    25861 tcgaacatta ttaaaagtaa aggaaatcta gtgcgagtaa aaattaatct caaatgctcc
    25921 tcttgtggca gtatcaatta cctaaccagt aaaaattcaa aaacccatcc agacaagatt
    25981 gaggttttaa agtattgtcc caaggaaaga aaagtaaccc tacatcttga atctaagtag
    26041 attttatggt aaaataatag ggattttaag gagtttgata tgtataacct attattaacc
    26101 attttattag tattatctgt tgtgattgtg attgcaattt tcatgcaacc aaccaaaaac
    26161 caatccagca atgtatttga tgccagttca ggtgatttgt ttgaacgtag taaagctcgc
    26221 ggttttgaag ctgtaatgca gcgtttgaca gggattttag tctttttctg gctagccatt
    26281 gccttagcat tgacggtatt atcaagtaga taagaaaata atgggcagga ctaggtcttt
    26341 gcctcttttt atttttaaag gatgtttgag aaggttttac agtaaaagaa aattaaaaaa
    26401 tctagaaaga aaatatgaaa gatagaataa aagaatattt acaagacaag ggaaaggtga
    26461 ctgttaatga tttggctcag gctttgggaa aagacagttc caaggatttt cgtgagttga
    26521 ttaaaacctt gtccttaatg gaaagaaagc accaaattcg ttttgaagaa gatggtagtc
    26581 tgacattaga aattaagaaa aaacatgaga ttaccctcaa ggggattttt catgcccata
    26641 aaaatggctt tggctttgtt agtctggaag gcgaggagga cgaccttttt gtagggaaaa
    26701 atgatgtcaa ctatgctatt gatggtgata ccgtcgaggt agtgattaag aaagtcgctg
    26761 accgcaataa gggaacagca gcagaagcca aaattattga tatcctagaa cacagtttga
    26821 caacagttgt cgggcaaatc gttctggatc aggaaaaacc taagtatgct ggctatattc
    26881 gttcaaaaaa tcagaaaatc agtcaaccga tttatgttaa gaaaccagcc ctaaaattag
    26941 aaggaacaga agttctcaaa gtctttatcg ataaataccc aagcaagaaa catgatttct
    27001 ttgtcgcgag tgttctcgat gtagtgggac actcaacgga tgtcggaatt gatgttcttg
    27061 aggtcttgga atcaatggac attgtatccg agtttccaga agctgttgtt aaggaagcag
    27121 aaagtgtgcc tgatgctccg tctcaaaagg atatggaagg tcgtctggat ctaagagatg
    27181 aaattacctt taccattgac ggtgcggatg ccaaggactt ggacgatgca gtgcatatca
    27241 aggctctgaa aaatggcaat ctggagcttg gggttcacat cgcagatgtt tcttattatg
    27301 tgaccgaggg gtctgccctt gacaaggaag cccttaaccg tgcgacttct gtttacgtga
    27361 cagaccgagt ggtgccaatg cttccagaac gactatcaaa tggcatctgc tctctcaatc
    27421 cccaagttga ccgcctgacc cagtctgcta ttatggagat tgataaacat ggtcgtgtgg
    27481 tcaactatac cattacacaa acagttatca agaccagttt tcgtatgacc tatagcgatg
    27541 tcaatgatat cctagctggc gatgaagaaa agagaaaaga atatcataaa attgtatcaa
    27601 gtatcgaact catggccaag cttcatgaaa ctttagaaaa catgcgtgtg aaacgtggag
    27661 ctctcaattt tgataccaat gaagcgaaga ttttagtgga taaacaaggt aagcctgttg
    27721 atatcgttct tcggcagcgt ggtattgccg agcggatgat tgagtctttt atgttgatgg
    27781 ctaatgaaac agttgccgaa catttcagca agttggattt gccttttatc tatcgaattc
    27841 acgaggagcc taaggctgaa aaggttcaga agtttattga ttatgcttcg agttttggct
    27901 tgcgcattta tggaactgcc agtgagatta gtcaggaggc acttcaagac atcatgcgtg
    27961 ctgttgaggg agaaccttat gcagatgtat tgtccatgat gcttcttcgc tctatgcagc
    28021 aggctcgtta ttcggagcac aatcacggcc actatggact agctgctgac tattatactc
    28081 actttaccag tccaattcgt cgttatccag accttcttgt tcaccgtatg attcgggatt
    28141 acggccgttc taaggaaata gcagagcatt ttgaacaagt gattccagag attgcgaccc
    28201 agtcttccaa ccgtgaacgt cgtgccatag aagctgagcg tgaagtcgaa gccatgaaaa
    28261 aggctgagta tatggaagaa tacgtgggtg aagagtatga tgcagttgta tcaagtattg
    28321 tcaaattcgg tctctttgtc gaattgccaa acacagttga aggcttgatt cacatcacta
    28381 atctacctga attttatcat ttcaatgagc gtgatttgac tcttcgtgga gaaaaatcag
    28441 gtatcacttt ccgagtgggt cagcagatcc gtatccgtgt tgaaagagcg gataaaatga
    28501 ctggagagat tgatttttca ttcgtaccta gtgagtttga tgtgattgaa aaaggcttga
    28561 aacagtctag tcatagtggc agagggcgtg gttcaaatcg tcgttcggat aagaaggaag
    28621 acaagagaaa atcaggacgc tcaaatgata agcgtaagca ttcacaaaaa gacaagaaga
    28681 aaaaaggaaa gaaacctttt tacaaggaag tagctaagaa aggagccaag catggcaaag
    28741 ggcgagggaa aggtcgtcgc acaaaataaa aaggcacgcc acgactatac aatcgtagat
    28801 acgctagagg cagggatggt cctgactgga actgaaatca agagtgtacg agctgctcga
    28861 attaatctca aggatggctt tgctcaagtg aaaaatggag aagtttggct gagcaatgtt
    28921 catatcgcgc cttacgaaga gggcaatatc tggaaccagg aaccagaacg tcgtcgtaaa
    28981 ctcctgctcc ataaaaagca aattcaaaaa ttggaacaag agaccaaagg gacaggaatg
    29041 accttagttc cccttaaggt ctatataaaa gatggctacg ctaagcttct tttaggactt
    29101 gccaaaggga agcatgacta tgacaaacgg gagtctatca aacgtcgtga gcaaaatcga
    29161 gatatcgcgc gtgtgatgaa agctgttaat cagcgataaa aagaggaatt gaaaatggaa
    29221 aaattagttg cctataaacg catgcctttg tggaataaac aaacaatgcc tgaagatgtt
    29281 cagcaaaagc acaatacaaa agttgggact tgggggaaaa ttactgtctt gaagggagct
    29341 ctcaagttta ttgaattgac agaagaaggg gaagttctag ctgaacacct ctttgaagca
    29401 ggggcagaca atccaatggc ccaacctcaa gcctggcacc gagtggaagc tgccacagat
    29461 gatgtggaat ggtacttgga attttattgt aaacctgagg attattttgc taaaaaatac
    29521 aataccaatc ctgttcattc agaggtccta gaggccatgc agacagtgaa acaagggaaa
    29581 gctttggatt tgggttgtgg tcaggggcgt aattctcttt ttctagccca gcaagatttt
    29641 gatgtgacgg ctgtagatca aaatggacta gctcttgaaa tcttgcaaag cattgtggag
    29701 caggaagatt tggacatgcc tgttggcctt tacgatatca attcagctag cattgaacaa
    29761 gaatatgatt ttatcgtttc aacagttgtt ctcatgtttc tacaagcgga ccgcattcca
    29821 gctattattc aaaatatgca ggagaaaacc agtgttggtg gttacaacct tatcgtttgt
    29881 gccatggaca cggaggatta tccttgctcg gttaatttcc cattcacctt taaagaagga
    29941 gaactggcag actattacaa ggattgggaa ttggttaagt acaatgaaaa tccaggccat
    30001 ttgcaccgtc gcgatgagaa tggcaatcgt attcaactac gctttgcgac cttactagct
    30061 aagaaaatca agtaaacaca catgaagatt aggaattttc ctgatctttt ttctttttta
    30121 cgaatgatat agaaaaggag ggaattcatg tttgttgcga gagatgctag gggagaattg
    30181 gtaaatgtgt tagaggataa acttgagaag caagcataca cctgcccagc ttgtggaggc
    30241 cagctccatt tgcgtcaagg accaagtgta cggacgcatt ttgcccataa atccttaaaa
    30301 gactgtgatt ttttctttga aaatgaaagt ccagaacacc tggccaataa ggaatccctc
    30361 tatcactggt tgaaaaaaga gacaaaggtt caattagagt acccgctttc agaacttaaa
    30421 cagattgcgg atgtatttgt aaatggcaat ctagctctag aagttcagtg tagtcccttg
    30481 cctcagaaag tccttaaaga gcgaagtgag ggatatcgta gtcagggtta ccaagtactg
    30541 tggttgctgg gtcaaaaact gtggctcaag gagcgtttga ctcgtctaca gcaaggtttt
    30601 ctttatttca gtcaaaacat gggcttttat gtttgggaat tagacaagga aaaacaagtt
    30661 ttaagactca aatacctgat ttaccaggat ctccgcggta aactccatta tcaaatcaag
    30721 gaattttcct atggtcaagg ta
//
LOCUS       DAVBEO010000023        30074 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 009
            SAMEA1678075-rid20185393.denovo.023, whole genome shotgun sequence.
ACCESSION   DAVBEO010000023 DAVBEO010000000
VERSION     DAVBEO010000023.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678075
            Sequence Read Archive: ERR226392
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 30074)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 30074)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980207.1
            Genome Coverage       :: 150x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:50:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 72 of 147
            Pseudo Genes (incomplete)         :: 72 of 147
            Pseudo Genes (internal stop)      :: 42 of 147
            Pseudo Genes (multiple problems)  :: 32 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30074
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678075-rid20185393.denovo.023"
                     /strain="KS 009"
                     /db_xref="taxon:1313"
     gene            51..1100
                     /locus_tag="VQ543_001061"
     CDS             51..1100
                     /locus_tag="VQ543_001061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LLM class flavin-dependent oxidoreductase"
                     /protein_id="HET2611793.1"
                     /translation="MVELGISTFGEITELEGTGQTYSHAERIRQLVAEIELADKVGLD
                     VYGIGEHHRADFAVSAPEIVLAAGAVNTKKIRLTSAVSILSSMDPIRLFQQYATIDAL
                     SNGRAEIMAGRGSFTESFPLFGYDLKDYDSLFDEKLDLLQLVNEKTKLDWQGRLTQTI
                     AGKEVYPRPVQDKLPLWIATGGHVESTVKIAQAGLPIVYAIIGGNPRYFKKLIQAYRE
                     IGSEAVHADKDLKVGAHSWGWIAEDGEQAVKDYFHPTKQVVDAISKDRPHWQELRYEQ
                     YLEQVGSNGAMFVGNPDQVAEKLIRMIEDLGLDRFMLHLPLGSMPHDQVLRAIELFGT
                     QVAPKVRAYFAMKEA"
     gene            complement(1200..5042)
                     /gene="spuA"
                     /locus_tag="VQ543_001062"
     CDS             complement(1200..5042)
                     /gene="spuA"
                     /locus_tag="VQ543_001062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored pullulanase SpuA"
                     /protein_id="HET2611794.1"
                     /translation="MRKTPSHTEKKMVYSIRSLKNGTGSVLIGASLVLLAMATPTISS
                     DESTPTTNEPNNRNTTTLAQPLTDTAAGSGKNESDISSPGNANASLEKTEEKPAASPA
                     DPAPQTGQDRSSEPTTSTSPVTTETKAEEPIEDNYFRIHVKKLPEENKDAQGLWTWDD
                     VEKPSENWPNGALSFKDAKKDDYGYYLDVKLKGEQAKKISFLINNTAGKNLTGDKSVE
                     KLVPKMNEAWLDQDYKVFSYEPQPAGTVRVNYYRTDGNYDKKSLWYWGDVKNPSSAQW
                     PDGTDFTATGKYGRYIDIPLNEAAREFGFLLLDESKQGDDVKIRKENYKFTDLKNHSQ
                     IFLKDDDESIYTNPYYVHDIRMTGAQHVGTSSIESSFSTLVGAKKEDILKHSNITNHL
                     GNKVTITDVAIDEAGKKVTYSGDFSDTKHPYTVSYNSDQFTTKTSWRLKDETYSYDGK
                     LGADLKEEGKQVDLTLWSPSADKVSVVVYDKNDPDKVVGTVALEKGERGTWKQTLDST
                     NKLGITDFTGYYYQYQIERQGKTVLALDPYAKSLAAWNSDDSKIDDAHKVAKAAFVDP
                     AKLGPQDLTYGKIHNFKTREDAVIYEAHVRDFTSDPAIAKDLTKPFGTFEAFIEKLDY
                     LKDLGVTHIQLLPVLSYYFVNELKNHERLSDYASSNSNYNWGYDPQNYFSLTGMYSSD
                     PKNPEKRIAEFKNLINEIHKRGMGAILDVVYNHTAKVDLFEDLEPNYYHFMDADGTPR
                     TSFGGGRLGTTHHMTKRLLIDSIKYLVDTYKVDGFRFDMMGDHDAASIEEAYKAARAL
                     NPNLIMLGEGWRTYAGDENMPTKAADQDWMKHTDTVAVFSDDIRNNLKSGYPNEGQPA
                     FITGGKRDVNTIFKNLIAQPTNFEADSPGDVIQYIAAHDNLTLFDIIAQSIKKDPSKA
                     ENYAEIHRRLRLGNLMVLTAQGTPFIHSGQEYGRTKQFRDPAYKTPVAEDKVPNKSHL
                     LRDKDGNPFDYPYFIHDSYDSSDAVNKFDWTKATDGKAYPENVKSRDYMKGLIALRQS
                     TDAFRLKSLQDIKDRVHLITVPGQNGVEKEDVVIGYQITAPNGDIYAVFVNADEKARE
                     FNLGTAFAHLRNAEVLADENQAGSVGIANPKGLEWTEKGLKLNALTATVLRVSQNGTS
                     HESTAEEKPDSTPSKPEHQNEASHPEHQDPAPEARPDSTKPDTKVADAENKPSQATAD
                     SQAEQPAQEAQASSVKEAVRNESVENSSKKNIPATPDRQAELPNTGIKNENKLLFAGI
                     SLLALLGLGFLLKNKKEN"
     gene            5459..5872
                     /gene="rpsL"
                     /locus_tag="VQ543_001063"
     CDS             5459..5872
                     /gene="rpsL"
                     /locus_tag="VQ543_001063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12"
                     /protein_id="HET2611795.1"
                     /translation="MPTINQLVRKPRKSKVEKSKSPALNVGYNSHKKVQTNVSSPQKR
                     GVATRVGTMTPKKPNSALRKFARVRLSNLIEVTAYIPGIGHNLQEHSVVLLRGGRVKD
                     LPGVRYHIVRGALDTAGVNDRKQGRSKYGTKRPKA"
     gene            5892..6362
                     /gene="rpsG"
                     /locus_tag="VQ543_001064"
     CDS             5892..6362
                     /gene="rpsG"
                     /locus_tag="VQ543_001064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S7"
                     /protein_id="HET2611796.1"
                     /translation="MSRKNRAPKRDVLPDPLYNSQLVTRLINRVMLDGKRGTAASIVY
                     GAFEQIKEATGNDALEVFETAMENIMPVLEVRARRVGGSNYQVPVEVRPERRTTLGLR
                     WLVTIARLRGEHTMQDRLAKEILDAANNTGAAVKKREDTHRMAEANRAFAHFRW"
     gene            6787..8868
                     /gene="fusA"
                     /locus_tag="VQ543_001065"
     CDS             6787..8868
                     /gene="fusA"
                     /locus_tag="VQ543_001065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HET2611797.1"
                     /translation="MAREFSLEKTRNIGIMAHVDAGKTTTTERILYYTGKIHKIGETH
                     EGASQMDWMEQEQERGITITSAATTAQWNNHRVNIIDTPGHVDFTIEVQRSLRVLDGA
                     VTVLDSQSGVEPQTETVWRQATEYGVPRIVFANKMDKIGADFLYSVSTLHDRLQANAH
                     PIQLPIGSEDDFRGIIDLIKMKAEIYTNDLGTDILEEDIPAEYLDQAQEYREKLIEAV
                     AETDEELMMKYLEGEEITNEELKAGIRKATINVEFFPVLCGSAFKNKGVQLMLDAVID
                     YLPSPLDIPAIKGINPDTDAEEIRPASDEEPFAALAFKIMTDPFVGRLTFFRVYSGVL
                     QSGSYVLNTSKGKRERIGRILQMHANSRQEIDTVYSGDIAAAVGLKDTTTGDSLTDEK
                     AKIILESINVPEPVIQLMVEPKSKADQDKMGIALQKLAEEDPTFRVETNVETGETVIS
                     GMGELHLDVLVDRMRREFKVEANVGAPQVSYRETFRASTQARGFFKRQSGGKGQFGDV
                     WIEFTPNEEGKGFEFENAIVGGVVPREFIPAVEKGLVESMANGVLAGYPMVDVKAKLY
                     DGSYHDVDSSETAFKIAASLSLKEAAKSAQPAILEPMMLVTITVPEENLGDVMGHVTA
                     RRGRVDGMEAHGNSQIVRAYVPLAEMFGYATVLRSASQGRGTFMMVFDHYEDVPKSVQ
                     EEIIKKNKGED"
     gene            8972..13363
                     /locus_tag="VQ543_001066"
     CDS             8972..13363
                     /locus_tag="VQ543_001066"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000071418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PolC-type DNA polymerase III"
                     /protein_id="HET2611798.1"
                     /translation="MSNSFEILMNQLGMPAEMRQAPALAQANIERVVVHKISKVWEFH
                     FVFSNILPIEIFLELKKGLSEEFSKTGNKAVFEIKARSQEFSNQLLQSYYREAFSEGP
                     CASQGFKSLYQNLQVRAEGNQLFIEGSEAIDKEHFKKNHLPNLAKQLEKFGFPTFNCQ
                     VEKNDVLTQEQEEAFHAENEQIVQAANEEALRAMEQLEQMAPPPAEEKPAFDFQAKKA
                     AAKPKLDKAEITPMIEVTTEENRLVFEGVVFDVEQKVTRTGRVLINFKMTDYTSSFSM
                     QKWVKNEEEAQKFDLIKKNSWLRVRGNVEMNNFTRDLTMNVQDLQEVVHYERKDLMPE
                     GERRVEFHAHTNMSTMDALPEVEEIVATAAKWGHKAVAITDHGNVQSFPHGYKAAKKA
                     GIQLIYGMEANIVEDRVPIVYNEVEMDLSEATYVVFDVETTGLSAIYNDLIQVAASKM
                     YKGNVIAEFDEFINPGHPLSAFTTELTGITDDHVKNAKPLEQVLQEFQEFCKDTVLVA
                     HNATFDVGFMNANYERHDLPKISQPVIDTLEFARNLYPEYKRHGLGPLTKRFGVALEH
                     HHMANYDAEATGRLLFIFIKEVAEKHGVTDLARLNIDLISPDSYKKARIKHATIYVKN
                     QVGLKNIFKLVSLSNTKYFEGVPRIPRTVLDAHREGLILGSACSEGEVFDVVVSQGVD
                     AAVEVAKYYDFIEVMPPAIYAPLIAKEQVKDMEELQTIIKSLIEVGDRLGKPVLATGN
                     VHYIEPEEEIYREIIVRSLGQGAMINRTIGHGEHAQPAPLPKAHFRTTNEMLDEFAFL
                     GEELARKLVIENTNALAEIFESVEVVKGDLYTPFIDKAEETVAELTYKKAFEIYGNPL
                     PDIVDLRIEKELTSILGNGFAVIYLASQMLVQRSNERGYLVGSRGSVGSSFVATMIGI
                     TEVNPLSPHYVCGQCQYSEFITDGSYGSGFDMPHKDCPNCGHKLSKNGQDIPFETFLG
                     FDGDKVPDIDLNFSGEDQPSAHLDVRDIFGEEYAFRAGTVGTVAAKTAYGFVKGYERD
                     YGKFYRDAEVERLAQGAAGVKRTTGQHPGGIVVIPNYMDVYDFTPVQYPADDVTAEWQ
                     TTHFNFHDIDENVLKLDVLGHDDPTMIRKLQDLSGIDPNKIPMDDEGVMALFSGTDVL
                     GVTPEQIGTPTGMLGIPEFGTNFVRGMVDETHPTTFAELLQLSGLSHGTDVWLGNAQD
                     LIKQGIADLSTVIGCRDDIMVYLMHAGLEPKMAFTIMERVRKGLWLKISEEERNGYIE
                     AMKANKVPEWYIESCGKIKYMFPKAHAAAYVMMALRVAYFKVHHPIYYYCAYFSIRAK
                     AFDIKTMGAGLEVIKRRMEEISEKRKNNEASNVEIDLYTTLEIVNEMWERGFKFGKLD
                     LYRSQATEFLIDGDTLIPPFVAMDGLGENVAKQLVRAREEGEFLSKTELRKRGGLSST
                     LVEKMDEMGILGNMPEDNQLSLFDELF"
     gene            13465..13728
                     /locus_tag="VQ543_001067"
     CDS             13465..13728
                     /locus_tag="VQ543_001067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB/DinJ family
                     antitoxin"
                     /protein_id="HET2611799.1"
                     /translation="MSKMSISIRLDSEVKEQAQQVFSNLGMDMTTAINIFLRQAIQYQ
                     GLPFDVRLDENRKLLQALTDLDQNRNMSQSFESVSDLMEDLRA"
     gene            13721..13999
                     /locus_tag="VQ543_001068"
     CDS             13721..13999
                     /locus_tag="VQ543_001068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013904578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system YafQ family
                     toxin"
                     /protein_id="HET2611800.1"
                     /translation="MLKIRYHKQFKKDFKLAMKRGLKAELLEEVLNFLVQEKEHPARY
                     RDHSLTASKHFQGVRECHTQPDWLLVYKVDKSELILNLLRTGSHSDLF"
     gene            14020..14172
                     /locus_tag="VQ543_001069"
     CDS             14020..14172
                     /locus_tag="VQ543_001069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000776615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2611801.1"
                     /translation="MKLRIFAEDKPAKKVFEYQLELADRTILLSTALLSGAIALAGIF
                     SALKEK"
     gene            14194..15435
                     /locus_tag="VQ543_001070"
     CDS             14194..15435
                     /locus_tag="VQ543_001070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000243957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HET2611802.1"
                     /translation="MVLPNFKENLGKYAKLLVANGINVQPGHTLALSIDVEQRELAHL
                     IVKEAYALGAHEVIVQWTDDVINREKFLHAPMERLDNVPEYKIAEMNYLLENKASRLG
                     VRSSDPGALNGVDADKLSASAKAMGLAMKPMRIATQSNKVSWTVAAAAGLEWAKKVFP
                     NAASDEEAVDFLWDQIFKTCRVYEADPVKAWEEHAAILKSKADMLNKEQFSALHYTAP
                     GTDLTLGLPKNHVWESAGAVNAQGEEFLPNMPTEEVFTAPDFRRADGYVTSTKPLSYN
                     GNIIEGIKVTFKDGQIVDITAEKGDQVMKDLVFKNAGARALGECALVPDPSPISQSGI
                     TFFNTLFDENASNHLAIGAAYATSVVDGAEMSEEELEAAGLNRSDVHVDFMIGSNQMD
                     IDGIREDGTRVPLFRNGNWAN"
     gene            15445..15675
                     /locus_tag="VQ543_001071"
     CDS             15445..15675
                     /locus_tag="VQ543_001071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000901571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HET2611803.1"
                     /translation="MLGSMFVGLLVGFLAGAMTNRGERMGCFGKMFLGWIGAFLGHLL
                     FGTWGPVLSGTAIIPAILGAMIVLAIFWRRGS"
     gene            15898..16620
                     /locus_tag="VQ543_001072"
     CDS             15898..16620
                     /locus_tag="VQ543_001072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HET2611804.1"
                     /translation="MRLDKFLVACAVGSRTEVKNLLKAGRVTVNGKKEKSAKLQIDEK
                     IDEIRFDGQVLEYEEFVYYMMNKPKGVISATEDPKHRTVLDLLDDLARSKEVFPVGRL
                     DIDTHGLLLLTNNGQLAHVLLSPKRHVDKTYQAQVKGIMTQEDVETFIKGIPLKDFTC
                     QPARLEILSTDAEKNQSQIRVTIAEGKFHQIKRMVGYCGKEVVDLQRLTMGTLVLDEN
                     LERGEWRRLTKEELEILRANII"
     gene            16837..18171
                     /gene="pepC"
                     /locus_tag="VQ543_001073"
     CDS             16837..18171
                     /gene="pepC"
                     /locus_tag="VQ543_001073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000991632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase C"
                     /protein_id="HET2611805.1"
                     /translation="MNAIQESFTDKLFANYEANVKYQAIENAASHNGIFAALECRQSH
                     VDNTPVFSLDLTKDKVTNQKASGRCWMFAALNTFRHKLISQYKLENFELSQAHTFFWD
                     KYEKSNWFLEQVIATSDQELTSRKVSFLLQTPQQDGGQWDMVVSLFEKYGVVPKSVYP
                     ESVSSSSSRELNAILNKLLRQDAQILRDLLVSGADQATVQAKKEDLLQEIFNFLAMSL
                     GLPPRKFDFAYRDKDNNYKSEKGITPQEFYKKYVNLPLEDYVSVINAPTADKPYGKSY
                     TVEMLGNVVGSRAVRYINVPMERLKELAIAQMQAGETVWFGSDVGQLSNRKAGILATD
                     VYDFESSMDIKLTQDKAGRLDYSESLMTHAMVLTGVDLDENGKSTKWKVENSWGDKVG
                     TDGYFVASDAWMDEYTYQIVVRKELLTAEEQAAYGAEPIVLAPWDPMGALAE"
     gene            complement(18227..19138)
                     /locus_tag="VQ543_001074"
     CDS             complement(18227..19138)
                     /locus_tag="VQ543_001074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HET2611806.1"
                     /translation="MTEKLQLTKSDRKKVWWRSTFLQGSWNFERMQNLGWAYTLIPAI
                     KKLYTKKEDQIAALERHLEFFNTHPYVAAPVMGVTLALEEERANGVEIDDAAIQGVKI
                     GMMGPLAGIGDPVFWFTVRPILGSLGASLALTGNILGPLLFFVAWNLIRMSFLWYVQE
                     IGYKAGSEITKDMSGGILQDITKGASILGMFILAVLVQRWVNIKFAFDVSKVQLDEKA
                     YIHWDKLPEGSKGIQEAFAQVGQGLSQTPEKVTTFQQNLDMLIPGLSGLLLTLLCMYL
                     LKKKVSPITIILALFAVGIVAHVLHIM"
     gene            complement(19162..19965)
                     /locus_tag="VQ543_001075"
     CDS             complement(19162..19965)
                     /locus_tag="VQ543_001075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter subunit
                     IIC"
                     /protein_id="HET2611807.1"
                     /translation="MSIISMVLVVVVAFFAGLEGILDQFQFHQPLVACTLIGLVTGHL
                     EAGIILGGSLQMIALGWSNIGAAIAPDAALASVAAAIIMVLGGDFTKTGIGVAQAVAI
                     PLAVAGLFLTMIVRTISVGLVHTADAAAKKGDFGAVERAHFIALLFQGLRIALPAALL
                     LMVPTETVQSILSAMPDWLKDGMAIGGGMVVAVGYAMVINMMATREVWPFFALGFVLA
                     AVSDITLIGFGAIGVAIALIYLHLSKTGGNGGGGAATSNDPIGDILEDY"
     gene            complement(19993..20982)
                     /gene="manX"
                     /locus_tag="VQ543_001076"
     CDS             complement(19993..20982)
                     /gene="manX"
                     /locus_tag="VQ543_001076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000021981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIAB"
                     /protein_id="HET2611808.1"
                     /translation="MSIGIIIASHGEFAAGIHQSGSMIFGEQEKVQVVTFMPNEGPDD
                     LYAKFNNAVAAFDAEDEVLVLADLWSGSPFNQASRVMGENPERKFAIITGLNLPMLIQ
                     AYTERLMDAAAGVEKVAANIIKEAKDGIKALPEELNPVEEVASAAAAPVAQTAIPEGT
                     VIGDGKLKINLARLDTRLLHGQVATAWTPDSKANRIIVASDNVAKDDLRKELIKQAAP
                     GNVKANVVPIQKLIEISKDPRFGETHALILFETPQDALRAIEGGVPIKTLNVGSMAHS
                     TGKTLVNTVLSMDKEDVATFEKMRDLGVEFDVRKVPNDSKKDLFDLINKANVK"
     gene            complement(21215..22234)
                     /gene="adhP"
                     /locus_tag="VQ543_001077"
     CDS             complement(21215..22234)
                     /gene="adhP"
                     /locus_tag="VQ543_001077"
                     /EC_number="1.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase AdhP"
                     /protein_id="HET2611809.1"
                     /translation="MKAVVVNPESTGVAIEEKVLRPLETGEALVEVEYCGVCHTDLHV
                     AHGDFGQVPGRVLGHEGIGIVKEIAPDVKSLKVGDRVSVAWFFEGCGTCEYCTTGRET
                     LCRTVKNAGYSVDGGMAEQCIVTADYAVKVPDGLDPAQASSITCAGVTTYKAIKEAKV
                     EPGQWVVLYGAGGLGNLAVQYAKKVFNAHVIAVDINNDKLTLAKEVGADIVINGLEVE
                     DVAGLIKEKTDGGAHSAVVTAVSKVAFNQAVDSIRAGGRVVAVGLPSEMMELSIVKTV
                     LDGIQVIGSLVGTRKDLEEAFQFGAEGLVVPVVQKRPVEDAVAIFDEMEKGQIQGRMV
                     LDFTH"
     gene            complement(22573..23385)
                     /locus_tag="VQ543_001078"
     CDS             complement(22573..23385)
                     /locus_tag="VQ543_001078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000162344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HET2611810.1"
                     /translation="MTKKIIAVDLDGTLLNSDSQISDFTKRTIKKVAEKGHQVIITTG
                     RPYRMSKDFYRELGLDTPMINFNGSLTHLPDQVWDFEKCLTVDKKYLLDMVQRSEDIQ
                     ADFIAGEYRKKFYITNPNEEIANPKLFGVEAFQPEDQFQPELVTKDPNCILLQTRASD
                     KYALAKEMNAFYQHQLSINTWGGPLNILECTPKGVNKAFALDYLLKIMNRDKKDLIAF
                     GDEHNDTEMLAFAGKGYAMKNANPELLPYADEQISLTNDQDGVAKTLQDLFL"
     gene            23575..24993
                     /locus_tag="VQ543_001079"
     CDS             23575..24993
                     /locus_tag="VQ543_001079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HET2611811.1"
                     /translation="MDKLFKLKENGTDVRTEVLAGLTTFFAMSYILFVNPQILSQTGM
                     PAQGVFLATIIGAVAGTLMMAFYANLPYAQAPGMGLNAFFTFTVVFGLGYSWQEALAM
                     VFICGIISLIITLTNVRKMIIESIPNALRSAISAGIGVFLAYVGIKNAGLLKFTIDPG
                     NYTVVGEGADKAQATIAANSSAVPGLVSFNNPAVLVALAGLAITIFFVIKGIKGGIIL
                     SILTTTVLAIAVGLVDLSSIDFANNHVGAAFEDLKTIFGAALGSEGLGALVSDTARLP
                     ETLMAILAFSLTDIFDTIGTLIGTGEKVGIVATNGENHQSAKLDKALYSDLIGTTVGA
                     IAGTSNVTTYVESAAGIGAGGRTGLTALVVAICFAISSFFSPLLAIVPTAATAPILII
                     VGIMMLGSLKNIHWDDMSEAVPAFFTSIFMGFSYSITQGIAVGFLTYTLTKLVKGQVK
                     DVHAMIWILDALFILNYISMAL"
     gene            25046..25753
                     /locus_tag="VQ543_001080"
     CDS             25046..25753
                     /locus_tag="VQ543_001080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET2611812.1"
                     /translation="MKEKNMWKELLNRAGWILVFLLAVLLYQVPLVVTSILTLKEVAL
                     LQSGLIVTGLSIVVLALFIMGARKTKLASFNFSFFRAKDLARLGLSYLVIVGSNILGS
                     ILLQLSNETTTANQSQINDMVQNSSLISSFFLLALLAPICEEILCRGIVPKKIFRGKE
                     NLGFVVGTIVFALLHQPSNLPSLLIYGGMSTVLSWTAYKTQRLEMSILLHMIVNGIAF
                     CLLALVVIMSRTLGISV"
     gene            25848..26822
                     /gene="folP"
                     /locus_tag="VQ543_001081"
     CDS             25848..26822
                     /gene="folP"
                     /locus_tag="VQ543_001081"
                     /EC_number="2.5.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydropteroate synthase"
                     /protein_id="HET2611813.1"
                     /translation="MMKILEGVTDMSSKANHAKTVICGIINVTPDSFSDGGQFFALEQ
                     ALQQARKLIAEGASMLDIGGESTRPGSSYVEIEEEIQRVVPVIKAIRKESDVLISIDT
                     WKSQVAEAALAAGANLVNDITGLMGDEKMAHVVAKAGAKVVIMFNPVMARPQHPSSLI
                     FPHFGFGQTFTEKELADFETLPIEDLMVAFFERALARAAEAGITPENILLDPGIGFGL
                     TKKENLLLLRDLDKLHQKGYPIFLGVSRKRFVINILEESGFEVNPETELGFRNRDTAS
                     AHVTSIAARQGVEVVRVHDVASHRMAVEIASAIRLADEAENLDLKQYK"
     gene            26824..28146
                     /locus_tag="VQ543_001082"
     CDS             26824..28146
                     /locus_tag="VQ543_001082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000658404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HET2611814.1"
                     /translation="MKEIENNQWIANYRTDQPHFGLERMVELLALRGNPHLKLKVLHI
                     GGTNGKGSTIAFLKKMLEKLGLRVGVFSSPYLIHYTDQISINGESISEARLEALMADY
                     QSLLEGEAVANLQGTTEFEIITALAYDYFASEQVDVAIMEVGMGGLLDSTNVCQPILT
                     GITTIGLDHVALLGDTLEAIAEQKAGIIKQGIPLVTGRIAPEALTVIDRIAEGKDAPR
                     LAYGTDYQVRHQESVVTGEVFDYTSAVRQGRFQTSLLGLYQIENAGMAIALLDTFCQE
                     DGRELASNDFLGQALEETSWPGRLEIVSRDPLMILDGAHNPHAIKALLVTLQERFADY
                     HKEILFTCIKTKALEDMLDLLGAMPDTELTLTHFADSRATDESVLKEAAKSRNLSYQD
                     WHDFLEQNLTDKKEEKQTVRIVTGSLYFLSQVRAYLMERKNENGYTKD"
     gene            28127..28681
                     /gene="folE"
                     /locus_tag="VQ543_001083"
     CDS             28127..28681
                     /gene="folE"
                     /locus_tag="VQ543_001083"
                     /EC_number="3.5.4.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP cyclohydrolase I FolE"
                     /protein_id="HET2611815.1"
                     /translation="MDTQKIEAAVKMIIEAVGENANREGLQETPARVARMYQEIFSGL
                     GQTAEEHLSKSFEIIDDNMVVEKDIFFHTMCEHHFLPFYGRAHIAYIPDGRVAGLSKL
                     ARTVEVYSKKPQIQERLNIEVADALMDYLGAKGAFVVIEAEHMCMSMRGVRKPGTATL
                     TTVARGLFETDKDLRDQAYRLMGL"
     gene            28724..29536
                     /gene="folK"
                     /locus_tag="VQ543_001084"
     CDS             28724..29536
                     /gene="folK"
                     /locus_tag="VQ543_001084"
                     /EC_number="2.7.6.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-amino-4-hydroxy-6-
                     hydroxymethyldihydropteridine diphosphokinase"
                     /protein_id="HET2611816.1"
                     /translation="MDQLQIKDLEMFAYHGLFPSEKELGQKFVVSAILSYDMTKAATD
                     LDLTASVHYGELCQQWTTWFQETSEDLIETVAYKLVERTFEFYPLVQEMKLELKKPWA
                     PVHLSLDTCSVTIHRRKQRAFIALGSNMGDKQANLKQAIDKLRARGIYILKESSVLAT
                     EPWGGVEQDSFANQVVEVETWLPAQDLLETLLAIESELGRVREVHWGPRLIDLDLLFV
                     EDQILYTDDLILPHPYIAERLFVLESLQEIAPHFIHPTLKQPIRNLYDALKK"
     gene            complement(29581..29898)
                     /locus_tag="VQ543_001085"
     CDS             complement(29581..29898)
                     /locus_tag="VQ543_001085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF960 domain-containing protein"
                     /protein_id="HET2611817.1"
                     /translation="MAFTNTHMRSASFGIVTSLPDDIIDSFWYIIDHFLKNVFELEEE
                     LEFQLLNNQGKITFHFSSQHLPTAIDFDFNHPFDPRYPPRVLVLDMYGRETILLPEEN
                     DLF"
BASE COUNT         8527 a         5841 c         7006 g         8700 t
ORIGIN      
        1 ttagaataat ttttcaaatt gaaggacaga gatagacaag gagaatcaca atggtagaat
       61 tgggaatttc aacatttggg gaaataacgg agcttgaagg gactggacaa acttacagtc
      121 atgctgaacg cattcgccag ttggtggcag agattgagct ggctgacaag gttggtttgg
      181 acgtatatgg gattggcgag caccatcggg cggattttgc agtatcagcc ccagagattg
      241 tcctggccgc tggggcagtc aataccaaga aaatccgttt gaccagtgca gtcagcattc
      301 tgtcaagcat ggatccgatt cgtttgttcc aacagtatgc cactatcgat gctttgtcaa
      361 atggacgagc ggagattatg gctggaaggg gctctttcac ggaatctttc cctctgtttg
      421 gttatgactt gaaagactac gactctcttt ttgatgagaa attagacttg cttcagttag
      481 tcaatgaaaa gaccaagtta gactggcaag gtcgattgac tcaaacgatt gctggtaaag
      541 aagtttatcc tcgtccagtt caggacaaat tgcccttgtg gatagctaca ggtggtcatg
      601 tcgaatcaac agtgaagatt gctcaggctg gtctaccgat tgtatatgct attattggtg
      661 gtaatccacg ttattttaaa aagttgattc aggcttatcg tgagattgga agcgaagcgg
      721 tccatgctga caaagacttg aaagtgggag cccattcttg ggggtggatt gcggaagatg
      781 gtgagcaggc ggtgaaagat tatttccatc cgactaagca agtggtggat gctatttcca
      841 aagaccgtcc gcactggcag gaattgcgtt atgagcaata tttggagcag gtagggtcaa
      901 atggcgccat gtttgttggc aatccagatc aggtggccga aaaattgatt cgcatgatag
      961 aggatttagg attggaccgc ttcatgcttc atctaccgct tggttctatg cctcatgacc
     1021 aggttctgag agctattgaa ctcttcggaa cacaagttgc acccaaagta cgagcttatt
     1081 ttgctatgaa agaggcttaa taaaaaatcc taatcaagtt tattaggaca acaaatattg
     1141 tacgaaaatt aatcccccga gctataatgc ttgggggatt tttctatagg agggctagtt
     1201 tagttctctt ttttattttt tagtaagaaa ccgagaccaa ggagcgcaag gaggctgatt
     1261 cctgcaaata ggagtttgtt ttcgttttta attcctgtat ttggaagttc agcttgtcta
     1321 tctggggttg caggtatatt tttcttgcta gagttttcta ccgattcgtt tcgaaccgct
     1381 tcttttacag atgatgcttg tgcttcttgt gctggttgtt cagcttgtga atcagctgta
     1441 gcttggctag gtttattttc cgcatcagct actttggtat ctggtttagt agaatcaggt
     1501 ctagcttctg gagctggatc ttgatgttca gggtgagaag cttcattttg atgttcaggc
     1561 ttggaagggg ttgagtctgg tttctcttct gcagttgact catggctagt tccattttga
     1621 gagactcgaa gaacagtagc tgtaagggca ttcaatttca agcctttttc agtccattca
     1681 agtcctttcg ggttggcaat tccgactgat cctgcttggt tttcatctgc caaaacttcc
     1741 gcatttctta gatgtgcaaa ggcagttccc aaattaaatt cgcgagcttt ttcatccgca
     1801 ttgacaaaga ctgcgtagat atcgccgttt ggagcagtga tttgatagcc aatcactaca
     1861 tcctcttttt ccacaccatt ttggcctggg acagtgatga ggtggacacg gtctttgata
     1921 tcttgaagac tcttaagtcg gaaggcatct gtagattgac gaagggcaat caaacctttc
     1981 atatagtcac ggctcttgac attttcagga taagctttac catctgtagc cttagtccag
     2041 tcaaacttgt tgactgcatc actagaatcg taagagtcat ggatgaagta aggatagtca
     2101 aatgggttgc cgtccttatc acgcaacaag tgagatttgt ttggaacctt atcctctgct
     2161 actggagtct tgtaggctgg gtcacggaat tgtttagtac gtccatattc ctgaccggag
     2221 tggataaatg gagttccttg agctgtcaag accatgagat ttccaagtcg taaacgacgg
     2281 tggatttcag catagttctc agccttgctt gggtcttttt tgatagactg ggcaatgatg
     2341 tcaaagaggg tcaagttatc atgggctgcg atgtattgga tgacatctcc agggctgtca
     2401 gcttcaaagt tagttggttg agcaatgaga tttttaaaga tggtgttgac atcacgcttg
     2461 ccacctgtga taaaggcagg ttgaccttcg tttggataac cagatttgag gttgttacgg
     2521 atgtcatctg aaaagacagc gacagtatcg gtatgtttca tccaatcttg gtcagcagct
     2581 ttagtaggca tgttttcatc accggcatag gttctccaac cttcaccaag catgatgagg
     2641 tttggattga gggcgcgtgc agccttgtaa gcttcttcga tagaagcggc gtcatggtct
     2701 cccatcatat cgaaacggaa gccatccact ttgtaggtat caactaggta tttgatagag
     2761 tcaattagga gccgtttggt catatggtgg gttgtcccca agcgtccacc accaaagcta
     2821 gttcgaggtg tgccatcggc atccataaag tggtagtagt ttggttccaa atcttcaaag
     2881 agatcgactt tggctgtgtg gttataaacg acatctagga tagctcccat accacgtttg
     2941 tggatttcgt tgatgaggtt tttaaattct gcgattcgtt tttctggatt cttaggatcg
     3001 cttgagtaca taccagtcaa ggagaagtag ttttgagggt catatcccca gttgtagttg
     3061 ctgttgcttg aagcgtagtc agacaagcgt tcatggtttt tcaattcatt gacaaagtag
     3121 taagacaaga ctggaaggag ctggatatgg gttacaccca agtctttgag atagtctagt
     3181 ttttcaatga aggcttcaaa agtcccaaat ggtttggtca agtcttttgc aatggcagga
     3241 tctgaagtga aatcacgcac atgagcttcg tagataacgg cgtcttcacg agtcttgaaa
     3301 ttgtgaatct taccataagt caagtcttga ggtccgagtt tagctggatc tacaaaggcg
     3361 gctttagcca ctttatgggc atcgtcaatc ttggaatcgt cgctattcca agcagcaaga
     3421 gatttagcgt aaggatcgag tgcaagaaca gttttacctt gacgctcgat ttggtattga
     3481 taatagtagc cagtgaaatc tgtgattccg agtttgtttg tgctgtctag agtttgtttc
     3541 caagttcctc tttccccttt ttcaagagcg acagttccaa ctactttgtc agggtcattc
     3601 ttgtcgtaga caacaacaga aaccttatca gcacttggtg accaaagggt caaatcaact
     3661 tgttttcctt cttcttttag gtcagctccc agtttgccat catagctgta tgtctcatct
     3721 ttcaggcgcc agcttgtttt ggtagtgaat tggtcggaat tgtagctaac agtataagga
     3781 tgttttgtgt cagagaaatc tccgctgtag gtcactttct taccagcttc atcgattgca
     3841 acatcggtaa tagttacctt gtttcctagg tgattagtga tgttggagtg tttgaggata
     3901 tcttcttttt tagcaccgac aagtgttgaa aagctacttt caatgctaga agtgcctacg
     3961 tgttgggctc ctgtcatacg gatatcatgg acatagtatg gatttgtgta aatcgattca
     4021 tcatcgtctt ttaggaaaat ttggctatga tttttcaaat ctgtgaactt ataattttct
     4081 ttacggattt tcacgtcgtc tccttgtttg ctctcatcta gtaataaaaa tccaaattct
     4141 cttgcggctt cattaagagg aatgtcgata tagcggccat atttgcctgt agccgtaaag
     4201 tctgttccgt caggccattg agcgctactt ggatttttca catctcccca gtaccagaga
     4261 gatttcttgt catagttgcc atctgtgcgg tagtagttga cgcgaacagt tcctgcaggc
     4321 tgtggctcgt aagagaaaac cttgtaatct tggtctaacc aagcttcgtt catttttgga
     4381 actagttttt ctacagattt atcgccggtt agattttttc cagctgtatt gttgatgagg
     4441 aagctaattt tcttggcttg ttctcccttt aatttgacat ctaggtaata gccgtagtca
     4501 tctttcttgg catccttgaa ggacaaagct ccgtttggcc agttttcaga tggtttttca
     4561 acatcgtccc aagtccatag tccttgagca tccttgtttt cttcaggaag ttttttgaca
     4621 tggatacgga agtagttatc ttcgatgggc tcttctgcct tagtttcagt tgttactgga
     4681 ctagtagaag tagttggctc acttgaacga tcttgtccag tttgtggtgc tggatcggct
     4741 gggcttgcag caggtttttc ttctgttttc tctagggaag cgtttgcatt tccaggtgaa
     4801 gaaatatcac tttcgttctt accagagcca gctgctgtat cagtaagagg ttgggcaagg
     4861 gtggttgtat ttctgttgtt gggttcgtta gtggttggtg tactttcgtc ggatgagata
     4921 gttggtgtag ccatggcaag caagacaagg cttgcgccga taaggacaga accagttcca
     4981 tttttgaggg aacggatgct gtagaccatt tttttctcag tgtgagatgg tgtttttctc
     5041 ataatgattc tccaatcaat aaatttctat atcagtatag catgtagtaa aacaatatgc
     5101 aagcgttttc tttgatttgt gaaagaaatt cttacttttg agaagttttc cgtactattt
     5161 tatatatcag tataaatgac ggagataaaa atgtcacgta agccaagccg tgttattagg
     5221 aagatgatgt gttctcagct atttttattc agaaattgat ctctaacatt accaataaaa
     5281 aagaaaaata tcttgacaag caagggaaaa ttttgttaca ataatagacg gtacttttta
     5341 cttttggtct ctcaagagtg tacagggacg tgctgacaaa tgttgcaaaa gtacacacag
     5401 atgatatctg tcaccaagtg tatcatcacc aaaaataaaa aaacacagga gaatgtagat
     5461 gcctacaatt aaccaattgg ttcgcaaacc gcgtaaatca aaagtagaaa aatctaaatc
     5521 accagctttg aacgttggtt acaatagtca taaaaaagtt caaacaaacg tttcttcacc
     5581 acaaaaacgt ggtgttgcaa ctcgtgttgg aacaatgaca cctaaaaaac ctaactcagc
     5641 ccttcgtaaa ttcgctcgtg tacgtttgag caaccttatc gaagttactg cctacatccc
     5701 aggtatcgga cacaacttgc aagagcacag cgtggtgctt cttcgcggtg gacgtgtaaa
     5761 agaccttcca ggggtacgtt accatatcgt ccgtggtgca cttgatactg caggtgttaa
     5821 cgatcgtaaa caaggccgtt ctaaatacgg tactaaacgt ccaaaagcat aaggaaaggg
     5881 gataaagaga aatgagtcgt aaaaatagag ctccaaaacg tgacgtattg ccagatccgc
     5941 tatacaattc acaactagtt actcgtctta tcaaccgcgt tatgcttgat ggtaaacgtg
     6001 gtactgctgc ttcaatcgtt tacggtgctt ttgagcaaat caaagaagct actggcaacg
     6061 atgcacttga agtatttgaa acagctatgg aaaacatcat gcctgtactt gaagtacgtg
     6121 cacgtcgtgt tggtggttct aactaccaag tcccagttga agttcgtcca gaacgtcgta
     6181 caacacttgg acttcgttgg ttggtaacaa tcgctcgtct tcgtggtgaa cacacaatgc
     6241 aagaccgtct tgcaaaagaa atcttggatg ctgctaacaa cactggtgca gcagttaaga
     6301 aacgtgaaga tactcaccgt atggctgaag ctaaccgtgc attcgcacac ttccgttggt
     6361 aagataggat gcgaaagcgt taagaaagtc ccagagaaaa tagggaatcg aagcaggttg
     6421 cggttgcaac caatgagatt catctttttc tccagacttt tagcttgagc tcaactaaat
     6481 catgatgcta ggaacggtaa ggatgcaagg taaaaatagg aaactgacgc agtattcgac
     6541 gaatacaagg agttttatct ttttcacgca gcatcccgtt ccagctcaca tcggctaact
     6601 aactttagcc cgggttcaaa ttagctaaat cgattagtat tagctataac tcagcttacc
     6661 atctcgtaag ttgaaaccaa caatagcatg aaaacattga gaacgggtag gtcctgccta
     6721 tccgttttta ttaaaatcgt gttataatag aatagaaatc aaaaataaat aggagaaaca
     6781 aacctcatgg cacgcgaatt ttcacttgaa aaaactcgta atatcggtat catggctcac
     6841 gtcgatgccg gtaaaacaac aactactgag cgtattcttt actacactgg taaaatccac
     6901 aaaatcggtg aaactcacga aggtgcgtca caaatggact ggatggagca agagcaagaa
     6961 cgtggtatca cgatcacatc tgctgcgacg acagctcaat ggaacaacca ccgcgtaaac
     7021 atcatcgaca caccaggaca cgtggacttc acaatcgaag tacaacgttc tcttcgtgta
     7081 ttggatggtg cggttaccgt tcttgactca caatcaggtg ttgagcctca aactgaaaca
     7141 gtttggcgtc aagcaactga gtacggagtt ccacgtatcg tatttgccaa caaaatggac
     7201 aaaatcggtg ctgacttcct ttactctgta agcacacttc acgatcgtct tcaagcaaat
     7261 gcacacccaa tccaattgcc aatcggttct gaagatgact tccgtggtat cattgacttg
     7321 atcaagatga aagctgaaat ctatactaac gaccttggta cggatatcct tgaagaagac
     7381 atcccagctg aataccttga ccaagctcaa gaataccgtg aaaaattgat tgaagcagtt
     7441 gctgaaactg acgaagaatt gatgatgaaa tacctcgaag gtgaagaaat cactaacgaa
     7501 gaattgaaag ctggtatccg taaagcgact atcaacgttg aattcttccc agtattgtgt
     7561 ggttcagcct tcaaaaacaa aggtgttcaa ttgatgcttg atgcggttat cgactacctt
     7621 ccaagcccac ttgacatccc agcaatcaaa ggtattaacc cagatacaga cgctgaagaa
     7681 attcgtccag catctgacga agagccattt gcagctcttg ccttcaagat catgactgac
     7741 ccattcgtag gtcgtttgac attcttccgt gtttactcag gtgttcttca atcaggttca
     7801 tacgtattga atacttctaa aggtaaacgt gaacgtatcg gacgtatcct tcaaatgcac
     7861 gctaacagcc gtcaagaaat cgacactgtt tactcaggtg atatcgctgc tgccgttggt
     7921 ttgaaagata ctacaactgg tgactcattg acagatgaaa aagctaaaat catccttgag
     7981 tcaatcaacg ttccagaacc agttatccaa ttgatggttg agccaaaatc taaagctgac
     8041 caagacaaga tgggtatcgc ccttcaaaaa ttggctgaag aagatccaac attccgcgtt
     8101 gaaacaaacg ttgaaactgg tgaaacagtt atctcaggta tgggtgaact tcaccttgac
     8161 gtccttgttg atcgtatgcg tcgtgagttc aaagttgaag cgaacgtagg tgctcctcaa
     8221 gtatcttacc gtgaaacatt ccgcgcttct actcaagcac gtggattctt caaacgtcag
     8281 tctggtggta aaggtcaatt cggtgatgta tggattgaat ttactccaaa cgaagaaggt
     8341 aaaggattcg aattcgaaaa cgcaatcgtc ggtggtgtgg ttcctcgtga atttatccca
     8401 gcggttgaaa aaggtttggt agaatctatg gctaacggtg ttcttgcagg ttacccaatg
     8461 gttgacgtta aagctaagct ttatgatggt tcatatcacg atgtcgactc atctgaaact
     8521 gccttcaaga ttgcggcttc actttccctt aaagaagctg ctaaatcagc acaaccagct
     8581 atccttgaac caatgatgct tgtaacaatc actgttccag aagaaaacct tggtgatgtt
     8641 atgggtcacg taactgctcg tcgtggacgt gtagatggta tggaagcaca cggtaacagc
     8701 caaatcgttc gtgcttacgt tccacttgct gaaatgttcg gttacgcaac agttcttcgt
     8761 tctgcatctc aaggacgtgg tacattcatg atggtatttg accactacga agatgtacct
     8821 aagtcagtac aagaagaaat tattaagaaa aataaaggtg aagactaatc cgtcctcact
     8881 ctagaaggaa gtcacttagt ggcttccttt tgtctttaga aaatacctct aaatatggta
     8941 aaatagtaga agaataatgt gaggaaaatg aatgtcaaat agttttgaaa ttttgatgaa
     9001 tcaattgggg atgcctgctg aaatgagaca ggctcctgct ttagcacagg ccaatattga
     9061 gcgagttgtg gttcataaaa ttagtaaggt atgggagttt catttcgtat tttctaatat
     9121 tttaccgatt gaaatctttt tagaattaaa gaaaggtttg agcgaagaat tttctaagac
     9181 aggcaataaa gctgtttttg aaattaaggc tcggtctcaa gaattttcaa atcagctctt
     9241 gcagtcctac tatagggagg ctttctctga aggtccatgt gctagtcaag gttttaagtc
     9301 cctttatcaa aatttgcaag ttcgtgctga gggtaatcag ctatttattg aaggatctga
     9361 agcgattgat aaggaacatt ttaagaagaa tcatcttcct aatttagcca aacaacttga
     9421 aaagtttggt tttccaactt ttaactgtca agtcgagaag aatgatgtcc tgacccaaga
     9481 gcaggaagag gcctttcatg ctgaaaatga gcagattgtt caagctgcca atgaggaagc
     9541 gctccgtgct atggaacaac tggagcagat ggcacctcct ccagcggaag agaaaccagc
     9601 ctttgatttt caagcgaaaa aagctgcagc taaacccaag ctggataagg cggagattac
     9661 tcctatgatc gaagtgacga cagaggaaaa tcgtctggta tttgaagggg ttgtttttga
     9721 tgtggagcaa aaagtgacta gaacaggtcg tgttttaatc aactttaaaa tgacggacta
     9781 tacttcaagt ttttctatgc aaaagtgggt taaaaacgag gaagaggccc agaagtttga
     9841 cctcatcaag aagaattctt ggctccgagt tcgagggaat gtggagatga ataacttcac
     9901 acgcgatttg actatgaacg tacaggatct gcaggaagtt gttcactatg agcggaagga
     9961 tttgatgcca gaaggtgagc gtcgggttga gtttcatgct catactaaca tgtcgactat
    10021 ggatgctttg ccagaggtcg aagagattgt tgcaacagct gctaagtggg gacacaaggc
    10081 ggttgctatc acggaccatg ggaatgtcca gtcctttcca catggctata aggcggctaa
    10141 gaaagcggga atccagctga tctatgggat ggaagccaat atcgtggagg accgtgtccc
    10201 tatcgtctat aacgaagtgg agatggactt gtcagaagca acctacgtgg tctttgacgt
    10261 ggaaacgacg ggactttcag ctatctataa tgacttgatt caggttgcgg cttctaagat
    10321 gtacaagggg aatgttattg ctgaatttga tgaatttatc aatcctgggc atcccttgtc
    10381 agcctttact acagagttaa ctggaattac agatgatcat gtcaaaaatg ccaaaccact
    10441 agaacaagtt ttgcaagaat tccaagaatt ttgcaaggat acggtcctag ttgcccacaa
    10501 tgctaccttt gacgttggct ttatgaatgc taattatgag cggcatgatc ttccaaagat
    10561 tagtcagcca gttattgata cgctggagtt tgctagaaac ctctatcctg agtataaacg
    10621 ccatggtttg gggcctttga ccaagcgttt tggtgtggcc ttggaacatc accacatggc
    10681 caactacgat gcggaagcga ctggtcgtct gcttttcatc tttatcaaag aggtagcaga
    10741 aaaacatggt gtgaccgatt tagctagact caacattgat ctaatcagtc cagattctta
    10801 caaaaaagct cggatcaagc atgcgaccat ctatgtcaag aatcaggtag gtctaaaaaa
    10861 tatctttaag ctggtttcct tgtctaatac caagtatttt gaaggagtgc cacggattcc
    10921 gagaacggtt ctagatgccc atcgagaggg cttgatttta ggttcagcct gttcagaggg
    10981 tgaagttttt gacgtggtcg tttctcaagg tgtggatgcg gcggttgagg tggccaagta
    11041 ttatgatttt atcgaggtca tgccaccggc tatctatgca cccttgattg ccaaagagca
    11101 ggtcaaggat atggaggaac tccagaccat tatcaagagt ttgatagagg ttggagaccg
    11161 ccttggcaag cctgttctgg ctacgggaaa tgttcactat atcgaaccgg aagaagagat
    11221 ttatcgtgaa attatcgtcc gtagtttggg acagggtgcg atgattaatc gaactatcgg
    11281 tcatggtgaa catgcccaac cagcaccact tccaaaggct cattttcgaa cgactaatga
    11341 gatgttggat gaatttgcct ttttgggaga ggaactggct cgtaaactgg ttattgaaaa
    11401 caccaatgcc ttggcagaaa tatttgaatc cgttgaagtc gttaagggtg acttgtatac
    11461 gcctttcatc gacaaggctg aagaaacagt tgctgagttg acctataaga aagcttttga
    11521 gatttatgga aatccgctgc cagatattgt tgatttgcgg attgaaaaag aattaacatc
    11581 catactgggg aatggatttg ctgtgattta tctggcatcg cagatgctgg tgcaacgttc
    11641 taatgaacgg ggttatttgg ttggttctcg tgggtctgtc ggatctagtt tcgttgcgac
    11701 catgattggg attacggagg tcaatcctct ctctcctcac tatgtctgtg gtcagtgtca
    11761 gtacagtgag tttatcacag atggttcgta cggttcagga tttgatatgc cccataagga
    11821 ctgtccaaac tgtggtcaca aactcagtaa aaacggacag gatattccgt ttgagacctt
    11881 ccttggtttt gatggggata aggttcctga tattgacttg aacttctcgg gagaagatca
    11941 gcctagcgcc cacttggatg tgcgtgatat ctttggtgaa gaatatgcct tccgtgcggg
    12001 aacggttggt acggtagctg ccaagactgc ctatggattt gtcaagggtt acgagcgaga
    12061 ttatggcaag ttttatcgtg atgcagaagt agaacgcctc gctcaaggag cggcgggtgt
    12121 caagcggaca acaggccaac acccgggggg aatcgttgtt attccgaact acatggatgt
    12181 ctacgatttt acgcctgtcc agtatccagc agatgatgtc acggctgaat ggcagaccac
    12241 tcactttaac ttccacgata tcgatgagaa cgtcctcaaa ctcgatgtac tgggacatga
    12301 tgatccgacc atgattcgaa aacttcagga tttgtctggt attgacccta ataaaattcc
    12361 tatggatgac gaaggcgtga tggcactctt ttctgggact gatgtactag gggtaacacc
    12421 tgaacaaatt ggaacgccta cgggtatgtt ggggattcca gagtttggaa caaatttcgt
    12481 acgtggaatg gtagacgaaa cccatccgac aacctttgcg gaattgcttc agctgtctgg
    12541 tctgtcccac ggtactgacg tttggttggg gaatgctcag gatctgatta agcaaggaat
    12601 agcggaccta tcgactgtta tcggttgtcg ggacgacatc atggtttacc tcatgcatgc
    12661 gggtctggaa cctaagatgg cctttaccat tatggaacgg gtacgtaagg gtttgtggct
    12721 aaagatttca gaagaggaga gaaatggcta tatcgaagcc atgaaggcta ataaggtgcc
    12781 agagtggtat atcgaatcct gtgggaaaat taagtacatg ttccctaagg cccatgcggc
    12841 agcctacgtt atgatggcct tgcgtgtagc ttacttcaag gttcaccatc ctatttatta
    12901 ctactgtgct tacttctcca ttcgtgctaa ggcttttgat atcaagacca tgggtgcggg
    12961 cttggaggtc atcaagcgca gaatggaaga aatctctgaa aaacggaaga acaatgaagc
    13021 ctctaatgtg gaaatcgatc tctatacaac tcttgagatt gtcaatgaga tgtgggaacg
    13081 aggtttcaag tttggtaaat tagatctcta ccgtagtcag gcgacagagt tcctcatcga
    13141 cggggatacc cttatcccac catttgtagc aatggatggt ctgggagaga acgttgccaa
    13201 gcaactggtg cgggcgcgtg aagagggaga attcctctct aaaacagaac tacgcaagcg
    13261 tggtggactc tcatcaacct tggttgaaaa gatggatgag atgggtattc ttggaaatat
    13321 gccagaggat aaccagttga gtttgtttga tgagttgttt taaaaaattg cttaataatc
    13381 tattaaaaga ggctaacgta tatccaatag atttacatta gctttctttt ttgttaaaat
    13441 agtctatgga aagagggtga gagtatgtca aagatgagta taagcatccg tctggatagt
    13501 gaggttaagg agcaggccca acaggtgttt agtaatctgg gaatggatat gacaacagct
    13561 attaatattt tccttcgtca ggcaattcaa tatcagggat taccttttga tgttagacta
    13621 gacgaaaatc ggaagttgct ccaagcgtta acggatttag accaaaatcg taatatgagc
    13681 cagtcttttg aatcagtctc agatttgatg gaggacttac gtgcttaaga ttcgttatca
    13741 taaacagttt aaaaaagatt ttaagttggc tatgaagcgt ggtttgaagg cagaattatt
    13801 agaagaagtt ttgaattttc tggttcaaga aaaagaacat cctgccagat atcgtgatca
    13861 ttcattgacg gcatccaagc attttcaagg agttcgtgaa tgccataccc agccagattg
    13921 gcttttggtt tataaagtag acaagtcgga attgatttta aatttgctga ggacaggcag
    13981 tcacagtgat ttattttaat ctattttaag ggggttctca tgaaactaag aatatttgcg
    14041 gaagataagc cggctaagaa ggtatttgaa tatcaattag aacttgctga tcgtacaatt
    14101 cttctatcga cagcactctt gtcaggtgct attgctttag caggaatctt ttctgctttg
    14161 aaagaaaaat aaaaatagaa aagagaaaac agaatggttt taccaaattt taaagaaaat
    14221 ctaggaaaat atgcgaaatt gttggttgcg aacggaatta acgtgcaacc tggtcacact
    14281 ttggctctct ctattgatgt ggagcaacgt gaattggcac atctaatcgt gaaagaagct
    14341 tatgccttgg gtgcgcatga ggtcatcgtt cagtggacag atgatgtgat taaccgtgag
    14401 aaattcctcc atgccccgat ggagcgtttg gacaatgtgc cagaatacaa gattgctgag
    14461 atgaactatc ttttggagaa caaggctagc cgtcttgggg ttcgttcatc tgatccaggt
    14521 gccttgaacg gagtggacgc tgacaagctt tcagcttctg ctaaagctat gggacttgcc
    14581 atgaagccta tgcgtatcgc aactcaatct aacaaggtta gctggactgt agcagccgct
    14641 gctggacttg agtgggctaa gaaagtcttc ccaaatgctg cgagcgacga agaagcagtt
    14701 gatttccttt gggatcaaat cttcaaaact tgtcgtgtct acgaagcaga tcctgttaag
    14761 gcttgggagg aacatgcagc cattctcaag agcaaggccg atatgcttaa taaggagcaa
    14821 ttttcagccc ttcactacac agcgccagga acagatttaa cacttggttt gccaaagaac
    14881 cacgtttggg aatcagctgg tgctgtcaat gcacagggcg aagaattctt gccaaatatg
    14941 ccgacagaag aggtcttcac agcgcctgac ttccgtcgtg cagatggtta tgtcacttct
    15001 acaaaaccgc ttagctacaa cggaaatatc attgaaggca ttaaggtgac ctttaaggat
    15061 ggacaaatcg tagatatcac tgctgagaag ggtgatcagg ttatgaaaga ccttgtcttt
    15121 aaaaatgcgg gtgcgcgtgc cttgggtgaa tgtgccttgg taccagatcc aagtccaatt
    15181 tctcagtcag gcattacctt ttttaacacc cttttcgatg aaaatgcgtc aaaccacttg
    15241 gctatcggtg cagcctatgc gactagcgtt gttgatggag cggagatgag cgaagaggag
    15301 cttgaagctg cagggcttaa ccgttcagat gttcacgtag actttatgat tggttctaac
    15361 caaatggata tcgatggtat tcgtgaggat ggaacgcggg tacctctttt ccgtaatggg
    15421 aattgggcaa attaaggaga taatatgtta ggaagtatgt tcgttggtct cctagtggga
    15481 tttttagcag gtgctatgac caatcgtgga gagcgaatgg gatgttttgg aaaaatgttt
    15541 ctcggttgga tcggagcctt tctaggtcac ttgctctttg gaacttgggg gccagtttta
    15601 tcaggaacag ctattatccc agcgatttta ggagccatga ttgttttagc tattttttgg
    15661 agacgaggaa gttaatttcc taaatctgat actcaatgaa aatcaaagag caaactagga
    15721 aactagccgc aggttgctca aagcactgct ttgaggttgc agatagaact gacgaagtca
    15781 gtaacatata tacggcaagg cgacgttgac gcggtttgaa gagatttttg aagagtatga
    15841 aacgaaaagg aggttggtca ttgtactagc ctccttttga tatgatataa tagttctatg
    15901 agattagata aatttttagt tgcctgtgcg gtgggaagtc ggactgaggt caaaaacttg
    15961 ctcaaggctg ggcgcgtgac tgtaaatggt aaaaaagaaa aatcagctaa attgcagatt
    16021 gatgaaaaaa tagatgagat tcgctttgat gggcaagtgt tggagtatga agagtttgtc
    16081 tactacatga tgaacaagcc caaaggagtt atctcagcga ctgaggatcc caagcacaga
    16141 accgttctgg acttgttgga tgacttggcg cggagtaagg aagtttttcc agtaggacgc
    16201 ttggatattg acacgcatgg tcttttgctc ttgaccaata atggtcagct ggctcatgtt
    16261 cttctttcgc ccaagcgtca tgtggacaag acttatcagg ctcaggtcaa gggaattatg
    16321 acccaagaag atgtggagac atttatcaag ggcattccgc tcaaagactt tacctgtcag
    16381 cccgctagac tggagattct ttccacagat gcagaaaaga atcagagcca aatccgtgtg
    16441 accattgcag aagggaagtt tcatcagatc aagcgtatgg tgggctactg tggcaaggaa
    16501 gtggtggact tgcaacgatt gactatggga actttagtat tagatgagaa cctggaacga
    16561 ggggaatggc gtcgcttgac caaggaagaa ttagaaattc tccgcgctaa tattatttaa
    16621 tttagtttaa tactcaatga aaatcaaaga gcaaactagg aaactagccg caggctgtac
    16681 ttgagtacgg caaggcgacg ttgacgtggt ttgaagagat tttcgaagag tataaattcg
    16741 aaaaaggtga gggacaatgt cctcgccttt tatgtttttt agttgcttcc tttgtgaaaa
    16801 gagttataat agactgtaga ataaaaggag gaatctatga acgcgattca agaatcattt
    16861 actgataaac tatttgccaa ctatgaagca aatgtaaaat accaagcgat tgaaaatgct
    16921 gccagccaca acggaatttt tgcagctctg gaatgtcgcc aaagccatgt agacaacaca
    16981 cctgttttct cattggattt aaccaaggac aaggtcacta accagaaagc gtctggtcgt
    17041 tgctggatgt ttgcggctct caacaccttc cgccacaaac tcatctcgca atacaaattg
    17101 gagaactttg agttgtcaca agcccacact ttcttctggg ataagtatga gaaatcaaac
    17161 tggttcttgg agcaagtcat tgcgacttca gaccaagaat tgactagccg caaggttagc
    17221 ttcttactcc aaacacctca acaagatggc ggtcaatggg atatggtcgt ttccctcttt
    17281 gaaaaatacg gtgtcgtgcc taagtcagtt tatcctgagt ctgtttcatc tagcagcagt
    17341 cgtgagctaa atgcgatcct taataaattg cttcgtcaag atgctcaaat cttgcgtgat
    17401 ttgcttgttt ctggtgcaga tcaagcgact gttcaagcta agaaagaaga cctcttgcaa
    17461 gaaatcttta actttcttgc tatgtcatta ggacttccac cacgcaagtt tgactttgct
    17521 tatcgcgata aagataacaa ctataaaagt gaaaaaggaa tcacaccaca agagttttac
    17581 aagaaatatg tcaatcttcc tttagaagac tacgtttctg ttatcaatgc tccaactgct
    17641 gataaacctt acggaaaatc ttacacagtt gagatgttgg ggaatgtggt tggtagccgt
    17701 gcagttcgct acatcaacgt tccaatggag cgcttgaaag aattggcgat tgcccaaatg
    17761 caagcaggtg agactgtttg gtttggttct gatgtcggcc agctcagcaa ccgtaaggct
    17821 ggcatccttg cgacagatgt ttatgacttt gaatcaagca tggacattaa acttactcaa
    17881 gacaaggctg gacgtttgga ctatagcgaa agcttgatga cccacgccat ggtcttgaca
    17941 ggtgttgact tggacgaaaa tggtaaatca accaagtgga aggttgaaaa ctcatgggga
    18001 gacaaggtcg gtacagatgg ttactttgtt gcctcagacg cttggatgga cgaatacaca
    18061 taccaaatcg ttgttcgtaa ggaattgctg acagcagaag aacaagctgc ctatggagca
    18121 gaaccaatcg tacttgcacc atgggatcca atgggagcct tggctgaata aaagcataga
    18181 aaaaaggaat cagattttag aacctggttc ctttttagtt gcttgattac atgatgtgaa
    18241 gaacatgtgc cacaataccc actgcgaaga gggcaaggat aatagtgatt ggagatactt
    18301 ttttcttaag taagtacatg caaagtaaag taaggagtag tcctgataat ccaggaatca
    18361 acatatccaa gttttgttgg aaagtagtaa ctttttcagg agtttgagac aatccttgtc
    18421 ctacttgtgc gaatgcttct tggatacctt tagacccttc tggcaattta tcccaatgga
    18481 tataagcctt ttcatctagt tgaactttag aaacatcgaa agcaaattta atatttaccc
    18541 agcgttgaac aaggacagca agaatgaaca tcccaaggat agaagctcct ttagtgatat
    18601 cttgaaggat accaccagac atatctttag tgatttctga tccagccttg tatccaatct
    18661 cttgaacata ccacaagaat gacatacgaa tcaagttcca tgcaacaaag aagaggagtg
    18721 gccccaagat attgccagta agggcaagtg aagcaccgag agatccaagg attgggcgta
    18781 ctgtaaacca gaatactggg tcaccgatac cagcaagagg tcccatcata ccgattttaa
    18841 ccccttggat agcagcgtca tcgatttcca caccgttagc acgttcttct tcaagcgcaa
    18901 gagtaacccc catgactgga gcagctacgt atggatgagt gttgaagaac tcaaggtgac
    18961 gctcaagagc agcgatttga tcttcttttt tagtatagag ttttttgata gctggaatga
    19021 gtgtataagc ccagcccaag ttttgcatcc gttcaaagtt ccaagaccct tgtaagaagg
    19081 ttgaacgcca ccaaactttt ttacgatctg atttagttaa ttgaagtttt tcagtcatga
    19141 tgttttcagt cctttcttat cttagtagtc ttctaggata tcgccgattg ggtcgttaga
    19201 agttgcggct cctccgccac catttccacc agttttagaa aggtgaaggt agataagagc
    19261 gatagcaaca ccgatagcac cgaatccgat tagagtaata tctgacacag cagcaagaac
    19321 gaaaccaaga gcgaagaatg gccatacttc acgagttgcc atcatgttga taaccatggc
    19381 gtaaccaacg gcaacgacca taccaccacc gatagccata ccatctttga gccagtctgg
    19441 catggcacta aggatacttt gtacagtttc agttggtacc ataaggagaa gagctgcagg
    19501 aagcgcgata cgaagtcctt ggaaaagtag cgcaatgaaa tgagcacgct ccacagcgcc
    19561 gaagtcacct tttttagcgg cagcatcagc agtgtgaacc aatccaactg aaattgtacg
    19621 aacaatcata gttaagaata gaccagctac ggcaagaggg atagcaaccg cttgggcaac
    19681 accgatacca gtcttggtaa agtcaccacc aagaaccatg ataatggcag cagcgacaga
    19741 agcaagtgca gcatcaggag cgatagcagc accgatattt gaccaaccaa gggcaatcat
    19801 ttgaagcgat ccaccgagga taatccctgc ttccaagtga cctgttacaa gcccaataag
    19861 ggtacaggct acaagtggtt ggtgaaattg gaactggtcg aggatgcctt caagacctgc
    19921 aaagaaggct acaacgacta ctaaaaccat agaaataata gacatgttta aaatcctttc
    19981 ataaataatg gcttatttga cattggcttt gttaatcaag tcaaacaaat cttttttaga
    20041 atcatttggt actttacgga catcaaattc aacacccaag tcacgcattt tttcaaatgt
    20101 agcaacatct tctttgtcca tagacaaaac ggtattgacc aatgttttac ctgttgagtg
    20161 agccatagaa ccaacgttaa gagtcttgat tggcacgccg ccttcgatgg cacgaagggc
    20221 atcttgaggt gtttcaaaca agataagggc atgtgtttct ccaaaacgtg ggtcttttga
    20281 aatctcaatc agtttttgaa ttggaaccac gttagccttg acattacctg gagctgcttg
    20341 tttaatcaat tctttacgaa ggtcgtcttt agccacgtta tctgaagcaa cgatgatacg
    20401 atttgctttt gaatctggag tccaagcagt tgcaacctga ccgtgaagta gacgtgtgtc
    20461 aagacgggca agattgattt tcaatttacc gtctccgata acagttcctt ctgggatagc
    20521 agtttgggca actggagcag ctgcagcgct tgcaacttct tcaactggat ttagctcttc
    20581 tggaagagct ttgatgccat ctttggcttc tttaatgata ttagcagcga ctttttctac
    20641 acctgcagca gcgtccatga ggcgctctgt gtaggcttga atcaacatcg gtaagttaag
    20701 tcctgtgatg atggcaaact tacgctcagg attttctccc atcacgcgac tagcttggtt
    20761 aaatggagaa ccactccaaa ggtcagccaa aactagaacc tcatcttctg cgtcaaatgc
    20821 agcaacagcg ttattaaact tagcgtatag atcatcagga ccttcatttg gcataaaggt
    20881 cacaacttga accttttctt gttcaccaaa gatcatagat cctgactgat gaatacccgc
    20941 agcaaattcg ccgtggctcg caataatgat tccgatactc attattgtca ttcctccttt
    21001 tttgttttag ttttcattta agaaaacttt aagactgttt aagtataaac cgttttcata
    21061 aaaaaagcaa ctatttatca taaaaaatta aaaaattttt atttttgtat gttgatatgt
    21121 tgagtttttg aggagtaatc ttgaattctt atttaaaatt taatataaaa aagttggaag
    21181 aagcttccaa cttttaaaat aggtttctat taaattagtg ggtgaagtcg agtaccatac
    21241 gtccttggat ttggcctttt tccatttcgt cgaaaatggc aacagcatct tctactggac
    21301 gtttttgaac aactgggact accagacctt ctgcaccaaa ttggaaggct tcttctaagt
    21361 ctttacgagt tccgacaaga gaaccgatga cttggattcc atcgaggact gttttaacga
    21421 tgctgagttc catcatttca gaaggaagac caacagcgac gacgcgacca ccagcacgaa
    21481 tggagtcaac agcctggttg aaggcaactt tagacacagc agttacgaca gctgaatgag
    21541 ctcctccatc agttttttct ttaatgagtc cagctacatc ttcaacttcg aggccgttaa
    21601 tcacaatgtc agcgcctact tcttttgcaa gggtaagttt gtcattgttg atatcgactg
    21661 cgataacatg agcattgaat acttttttag cgtattgaac agcgaggtta ccaagtccac
    21721 cagcaccgta aagaacaacc cattggcctg gttcaacttt tgcttctttg atagctttat
    21781 aggttgttac tccagcacat gtgatagaag aagcttgggc tggatcaagt ccgtcaggaa
    21841 ctttgacagc atagtcagca gttacgatac attgttcagc cataccaccg tctactgagt
    21901 agccagcatt tttcactgta cggcaaaggg tttcgcgacc agttgtacag tattcgcaag
    21961 tgccacatcc ttcaaagaac caagcaacgc tgacgcggtc accgacttta aggcttttca
    22021 catctggagc aatctcttta acgataccga taccttcgtg cccaagaaca cgtcctggga
    22081 cttgaccaaa gtcaccatga gcaacgtgga ggtcggtgtg gcaaacgcca cagtattcaa
    22141 cttctacaag tgcttcccca gtttcaagtg gacggagtac tttttcttca atagcaacac
    22201 cagtgctttc tggatttaca acaacagctt tcatagctat cctccttgat attgaccgag
    22261 aacagggaca acgggactgg attgattttt tgtcaacaga gtcgagtgtg acgagctctc
    22321 ttgtatttat atgtgaagta tatcacaaaa ggaagccttt tccaaggttt tggagacaaa
    22381 aagtagaaca atcgattaac tggttgatga gactgtgaaa agagcacaaa gaccagcttg
    22441 caagctggtc atactcttcg aaaatctctt caaaccacgt cagcttcatc tacaacctca
    22501 aagcagtgct ttgagcaacc tacggctagc ttcctagttt gctctttgat tctcattgag
    22561 tatcagtata ggttataaga ataagtcttg tagggttttg gcaaccccat cttggtcgtt
    22621 ggtaagggaa atttgctcat ctgcataagg gagtagctct ggattggcat ttttcatggc
    22681 ataacccttc ccagcaaaag cgagcatttc ggtatcattg tgttcatctc caaaggcaat
    22741 caaatctttt ttgtcacgat tcattatctt gagcaagtag tccaaagcaa aggccttgtt
    22801 gacacctttt ggggtacatt caaggatatt gagcggacct ccccaggtat tgatagaaag
    22861 ttgatgctgg tagaaggcgt tcatttcttt tgccaaggca tatttgtcac tggctctggt
    22921 ctgcaagagg atacagttag ggtccttggt caccaattca ggctggaatt gatcttcagg
    22981 ctggaaagct tctacaccaa atagtttggg attggcaatt tcttcattgg gatttgtaat
    23041 gtagaatttt ttacgatatt ctccagcgat aaaatcggct tgaatgtcct ctgaacgttg
    23101 aaccatatct agcagatatt ttttgtctac agtcaaacac ttttcaaaat cccaaacttg
    23161 gtctggtaaa tgagtaaggg atccgttgaa gttaatcata ggagtgtcta agcccagttc
    23221 acggtaaaaa tcttttgaca tacggtaagg gcgacctgtc gtaataataa cctgatggcc
    23281 tttttcagca acttttttga tggttctttt ggtaaagtca gaaatttgac tgtctgagtt
    23341 gagcagggtt ccatccaggt caactgcaat aatttttttc gtcatatgga cctttctagt
    23401 gtgttttcag ataagatgtc ttctattata acagaaagca ggcagaaaag cagattccaa
    23461 acaaaaaatg aaattggatt aatttcttaa acaaatcaaa caaagacatt gaaaaagtga
    23521 atgataaatg atataattct attattgttc gtaaaaatta aaaggagatt gatgatggac
    23581 aaattattta aactaaaaga gaacggtaca gacgttcgta cagaggttct cgctggttta
    23641 acaactttct ttgcaatgag ctatattctc tttgtaaacc cacaaatact ttcacaaaca
    23701 ggaatgcctg ctcagggcgt cttcctagcg acgattattg gtgcagtagc gggtaccttg
    23761 atgatggctt tttatgctaa cttaccttat gcccaagcac caggtatggg actcaatgcc
    23821 ttctttacct ttacagttgt attcgggctt ggttattctt ggcaagaagc cctagctatg
    23881 gtcttcatct gtgggattat ttcattgatt attaccttga caaatgttcg taaaatgatc
    23941 attgaatcga ttcccaatgc tcttcgctca gctatttcag ctggtatcgg tgtcttcctt
    24001 gcctatgtag ggattaagaa tgctggactt ttgaaattca cgattgatcc aggcaactat
    24061 actgttgtag gagaaggggc tgacaaagct caagcaacga ttgcagcaaa ctcttcagca
    24121 gttccaggat tggtcagctt taataatcca gctgttttag tggctcttgc aggacttgcc
    24181 attactatct tctttgtcat caaagggatt aaagggggaa ttattctctc tatcttgaca
    24241 acaactgttc ttgctattgc agttggtttg gttgatttgt ctagtatcga ttttgctaat
    24301 aaccatgttg gtgcagcttt tgaagatttg aagacaatct ttggtgcagc tcttggttca
    24361 gaaggtttgg gagctttggt ttcagataca gctcgcttgc ctgaaactct gatggccatt
    24421 cttgccttct cattgacaga tatttttgac acaattggta ccttgatcgg tacaggtgaa
    24481 aaagttggta ttgtagcgac aaatggtgaa aatcaccaat cagccaaatt ggataaggct
    24541 ctttactctg atttgattgg aacgacagtc ggtgccattg caggtacttc aaacgtaacg
    24601 acttatgttg agtctgctgc tggtatcggt gcaggtggac gtactggttt gacagccttg
    24661 gttgtagcta tctgttttgc gatttcaagc ttctttagcc cacttctagc gatcgtacca
    24721 acagcggcta cagctccaat cttgattatc gttgggatta tgatgcttgg tagcttgaaa
    24781 aatatccatt gggatgatat gtctgaagca gttcctgcct tcttcacatc tatctttatg
    24841 ggattcagct actctatcac tcaagggatt gcagttggtt tcttgactta cactttgact
    24901 aagcttgtca aaggtcaagt taaagatgtt catgccatga tttggatttt ggatgccttg
    24961 tttatcctta actacatcag catggcctta taatagaatg acccaggggg atttcccccc
    25021 ttttttaata caaaggagat aggtgatgaa agagaaaaat atgtggaaag aattgttgaa
    25081 tcgtgcaggc tggattttgg tctttttact tgccgtcctt ttatatcagg ttcccctagt
    25141 ggttacctct attttgactt taaaagaagt agccctgcta cagtcagggc tgatagttac
    25201 tggcctttca attgtggttc tggctctatt tattatggga gctcgtaaaa ccaagttagc
    25261 tagttttaat ttttcttttt ttagagctaa agatttggca cgtttgggct tgagttattt
    25321 agttattgtc gggtcaaata tacttggttc tatcttgttg caactgtcaa atgagacgac
    25381 aacagctaac cagtctcaga ttaacgatat ggttcagaat agttctctga tttctagctt
    25441 cttcttgcta gccttgcttg ctccaatttg tgaggaaatc ttgtgccgtg ggattgttcc
    25501 taaaaagatt ttccgaggca aggagaactt gggatttgta gtcggtacga ttgtgtttgc
    25561 tttattgcat caaccaagta atttaccttc tttattgatt tatggaggta tgtcgacagt
    25621 tctatcttgg acggcctaca agacccaacg tttggaaatg tcgatcttgc ttcacatgat
    25681 tgttaatggg attgctttct gtttgttggc tcttgtggtg attatgagtc ggacattagg
    25741 aatttctgtg taaaagtttt tatgtaggaa ccgacctctt tctactaggg aaagatgaat
    25801 gcaatcgtgt ccatcttttt ctttttatgg taaaatagaa aaataatatg atgaaaatcc
    25861 ttgagggagt gaccgatatg tcaagtaaag ccaatcatgc aaagacagtt atttgcggaa
    25921 ttatcaatgt aaccccagac tccttttcgg acggtggtca attttttgct cttgagcagg
    25981 cactccagca ggctcgtaaa ttgatagcag aaggagccag tatgctcgat atcggcggag
    26041 aatcgactcg gccgggcagt agctatgttg agatagaaga ggaaatccag cgtgttgttc
    26101 cagtgatcaa agcgattcgc aaggaaagtg atgtccttat ttctatcgat acttggaaaa
    26161 gtcaggtggc agaggctgct ttggctgctg gtgccaatct agttaatgat atcactggtc
    26221 tcatgggcga tgaaaaaatg gcccatgtgg ttgctaaagc tggagcgaaa gtagtcatca
    26281 tgtttaatcc agtcatggct cgacctcaac atcctagttc gcttatcttc cctcattttg
    26341 gctttggtca aacctttaca gaaaaagagt tagctgactt tgaaacattg ccaatcgaag
    26401 acttgatggt ggctttcttt gaacgagcac tagcgagagc ggcagaagct ggtattacac
    26461 cagaaaatat cctgttggat ccaggaattg gctttggtct gaccaagaaa gaaaatctcc
    26521 tccttttacg ggacctggat aaactacatc agaagggcta tccaatcttt ctcggagtgt
    26581 cgcgcaagcg atttgtcatc aatatccttg aagaaagtgg gtttgaagtc aatcctgaga
    26641 cagagcttgg tttccgaaat cgggacacgg cttcggctca tgtaactagt atcgctgcga
    26701 gacagggtgt agaagtggtg cgcgtgcatg acgtagctag tcacaggatg gcagttgaaa
    26761 ttgcctctgc cattcgtctg gctgatgaag cggaaaattt agatttaaaa caatataaat
    26821 aagatgaaag aaattgaaaa caatcagtgg attgctaact accggacgga tcaaccgcat
    26881 tttggattgg aacgaatggt ggaactgtta gctttgcgtg gcaatcccca tctcaaactc
    26941 aaggtcctcc atatcggagg gactaacggc aagggctcga ctattgcttt tttgaaaaag
    27001 atgctagaaa agctagggct gagagttggc gtgtttagct cgccctatct cattcattac
    27061 acagaccaga ttagcatcaa tggggaatcg atctcagaag cgaggctaga agctctcatg
    27121 gcagactatc agtctttgct ggagggagaa gcggtcgcca atttacaggg cacaaccgag
    27181 tttgagatta tcacagccct ggcctatgac tactttgcct cagagcaagt agatgtggcc
    27241 atcatggaag ttggcatggg tggacttttg gatagtacca atgtctgtca gcccattttg
    27301 acaggaatta caactattgg cttggatcat gtggccctac ttggtgacac cttggaggcc
    27361 atagcagagc agaaggcagg tattatcaaa caagggatac ccttggtaac agggcgtatt
    27421 gctccagaag ccttgactgt gattgaccgc attgcggaag ggaaagatgc gccgagactt
    27481 gcctacggga cagattatca ggttcgtcat caagaaagtg tggtgacagg ggaagtcttt
    27541 gactatacaa gtgctgtcag acaaggtcgc ttccagacta gcctgcttgg tttgtaccaa
    27601 atagagaatg ctgggatggc catagcttta cttgatactt tttgtcaaga agatggtcga
    27661 gagctagcaa gcaatgactt tcttggtcaa gccttggaag aaacaagttg gccagggcgt
    27721 ttggaaatcg tgtcaagaga tcccttgatg attttggatg gagcccataa tccccatgct
    27781 atcaaggcct tgttggtaac cttgcaagaa cgttttgcgg attatcataa ggaaatcctc
    27841 ttcacttgta tcaaaaccaa agccttggag gatatgttgg acttgctggg agccatgcca
    27901 gataccgagc ttactctaac acattttgcg gatagtcggg cgacggatga aagcgtgctg
    27961 aaagaggcag ctaagtctag aaatctcagc taccaagatt ggcatgattt tctagagcag
    28021 aatttgacag ataaaaaaga agagaaacaa acagttagga ttgtcacagg ttccttgtat
    28081 ttcttgagcc aagtgagggc ctatctgatg gagaggaaga acgagaatgg atacacaaaa
    28141 gattgaagca gctgtaaaaa tgattatcga ggctgtagga gagaacgcta atcgcgaggg
    28201 cttgcaggaa acacctgctc gtgtagcccg tatgtatcaa gagatttttt caggtcttgg
    28261 tcaaacagca gaggaacatt tgtcaaaatc ctttgaaatt attgacgata atatggtggt
    28321 agaaaaggat atctttttcc ataccatgtg tgaacaccac ttcttgccat tttatggtag
    28381 agcgcacatt gcctacattc cagatggtcg tgtggcaggc ttgtctaagc tagcccgtac
    28441 ggttgaagtt tattcgaaaa aaccacaaat tcaagaacgt ttgaatatcg aagtggccga
    28501 tgccttgatg gactatctag gtgctaaagg agcctttgtt gtcattgagg cggaacatat
    28561 gtgtatgagt atgcgtggtg ttagaaaacc aggcactgca accttgacga cagtagctcg
    28621 tggtctattt gaaacagata aggacctccg cgaccaagct tatcgtttaa tggggctata
    28681 aaaagaatcc gcttcaagcg gatttttcta gaaaggaatc attatggatc aactgcagat
    28741 taaggatttg gaaatgtttg cctatcatgg tctttttcct agtgagaaag aattggggca
    28801 gaaatttgtc gtttcagcca tcctatccta tgatatgacc aaggcagcta cagacttgga
    28861 tttaacagcc tctgtccatt acggagaatt atgtcagcag tggacgactt ggtttcagga
    28921 aacgagtgaa gatttgattg aaacggtagc ctataaactg gtggaacgta cctttgagtt
    28981 ttatcctctt gtccaagaaa tgaagttgga actgaaaaaa ccttgggcac cggtgcattt
    29041 gtcactagat acttgctcgg taaccattca tcgccgcaag caacgagcct ttatcgccct
    29101 aggaagcaat atgggagata aacaagcaaa cttgaagcaa gccattgaca aactgcgagc
    29161 tcgtggcatc tatattctca aagagtccag tgtcttagcg acggagcctt ggggtggagt
    29221 ggagcaggat agctttgcca atcaagtggt tgaggtggaa acctggctac cagcacaaga
    29281 cttgttagaa accttgttag ccattgagtc agagctggga cgggtgagag aagtgcattg
    29341 gggacctcgt ttgattgatt tggacttgct ctttgtggag gaccagatcc tttatacaga
    29401 cgacctcata ttgcctcatc cttacatagc ggaacgcctt tttgtccttg agtccttaca
    29461 ggaaattgcg cctcatttta tccatccgac attaaaacaa ccgatccgca acttgtatga
    29521 tgctttgaaa aaatagaaaa actctagttt tcagttactt gcaactgaag gctagagttt
    29581 ttaaaatagg tcattttctt ctgggaggag gatagtttct ctaccgtaca tgtctaaaac
    29641 cagtactctt gggggataac gagggtcgaa aggatggtta aagtcaaaat caatggctgt
    29701 agggaggtgt tgacttgaaa agtggaaggt aatctttcct tggttattaa gcaattgaaa
    29761 ctcgagttct tcttccaatt caaagacatt ttttaagaaa tgatcgatga tataccaaaa
    29821 agagtcaatg atgtcatcgg gcaagctggt aacaatgcca aaactagcag accgcatgtg
    29881 ggtattggta aaagccatat ctctgtcccc tttcttttcc cttatcatac agcaaatagg
    29941 attaaaaatc aagaaaaggt gattttttga aaaggatttt aactacaggg aaaaataagg
    30001 aaaaaaattc ccaaaaatct accgaagtta ataggtaaat tcccaaatta acttgattat
    30061 ataactttca gtta
//
LOCUS       DAVBEO010000024        29797 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 009
            SAMEA1678075-rid20185393.denovo.024, whole genome shotgun sequence.
ACCESSION   DAVBEO010000024 DAVBEO010000000
VERSION     DAVBEO010000024.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678075
            Sequence Read Archive: ERR226392
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 29797)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29797)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980207.1
            Genome Coverage       :: 150x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:50:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 72 of 147
            Pseudo Genes (incomplete)         :: 72 of 147
            Pseudo Genes (internal stop)      :: 42 of 147
            Pseudo Genes (multiple problems)  :: 32 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29797
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678075-rid20185393.denovo.024"
                     /strain="KS 009"
                     /db_xref="taxon:1313"
     gene            132..494
                     /locus_tag="VQ543_001086"
     CDS             132..494
                     /locus_tag="VQ543_001086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001234364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2611818.1"
                     /translation="MRLASESRQILDKLKDDVYNKLGYEVSYSSIVSQAVREYVPKKE
                     RIDWIKLKETAIPFSSLKQSNNWEYQTSLMLEKDVLILLSELQNFFLDVFQAKRIHRA
                     FCIRLCLRAQFLLSNNDS"
     gene            902..1201
                     /locus_tag="VQ543_001087"
     CDS             902..1201
                     /locus_tag="VQ543_001087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001081475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2611819.1"
                     /translation="MNRNVLNFLRTESAERVSLYIDKANRLEGDVTLLAPSSQDLEDI
                     KNAMFSNPNLELKVARLDVMKKIAYASTRNHYLTGATIFGDISKGTYNCDPKSYV"
     gene            complement(1296..1733)
                     /locus_tag="VQ543_001088"
     CDS             complement(1296..1733)
                     /locus_tag="VQ543_001088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000737922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2611820.1"
                     /translation="MKKLYRIHFIAIAVIDLLLFAFFITRLETSFEWLLLSGLIFFLA
                     QGLLLFLLVVRLKHQFAEIYPQINKKIRFYYLGVLTIDFLFFVLLAFISSQRFSSLMP
                     IITACHSTFYYMTADYLRENYPDFYDKHISNTYTILSISSFLV"
     gene            complement(1864..2498)
                     /locus_tag="VQ543_001089"
                     /pseudo
     CDS             complement(1864..2498)
                     /locus_tag="VQ543_001089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001819460.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide mononucleotide transporter"
     gene            complement(2708..3358)
                     /locus_tag="VQ543_001090"
     CDS             complement(2708..3358)
                     /locus_tag="VQ543_001090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000188500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent transcriptional regulator"
                     /protein_id="HET2611821.1"
                     /translation="MTPNKEDYLKCIYEIGIDLHKITNKEIAARMQVSPPAVTEMIKR
                     MKSENLILKDKECGYLLTDLGLKLVSELYRKHRLIEVFLVHHLDYTSDQIHEEAEVLE
                     HTVSDLFVERLDKLLGFPKTCPHGGTIPAKGELLVEINNLPLADIKEAGAYRLTRMHD
                     SFDILHYLDKHSLHIGDQLQVKQFDGFSNTFTILSNDEDLQVNMDIAKQLYVEKIN"
     gene            3470..4312
                     /locus_tag="VQ543_001091"
     CDS             3470..4312
                     /locus_tag="VQ543_001091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase family protein"
                     /protein_id="HET2611822.1"
                     /translation="MTKIALLSDIHGNTTALEAVLADARQLGVDEYWLLGDILMPGTG
                     RRRILDLLDQLPITARVLGNWEDSLWHGVRKELDSTRPSQRYLLRQCQYVLEEISLEE
                     IEVLHNQPLQIHRQFGDLTVGISHHLPDKNWGRELIHTGKQEEFDRLVTHPPCDIAVY
                     GHIHQQLLRYGTGGQLIVNPGSIGQPFFLDAQLRKDLRAQYMILEFDDKGLVDMDFRR
                     VDYDVAAELQLAKDLRLPYFEVYYESLVNGIHHTHHQEFLRELAQKEGCDRELDDWLK
                     SGND"
     gene            4388..4825
                     /locus_tag="VQ543_001092"
     CDS             4388..4825
                     /locus_tag="VQ543_001092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004263219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="HET2611823.1"
                     /translation="MQIPSRFTIATHMLIIIALEGKKSKVTSDFLAASVGVNPVIIRK
                     ILSQLKKAELISVARGTGGTDIVKDLKDISLLDVYQAVECLGKTGQLFSFHDNPNPNC
                     PVGAHIHDVLDQKLERIQLTMEAELGQTSLEKVVADAESQMKD"
     gene            4893..5195
                     /locus_tag="VQ543_001093"
     CDS             4893..5195
                     /locus_tag="VQ543_001093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000281600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2611824.1"
                     /translation="MYLVIGIVLAFIVSFWKDNRSLWNPVLFLLSLISSYFYLSYLFY
                     KNGYENVQLAFYVFAFVLLPFLLFLSGIFLIYNGVILLKREGRSKPHYLSMLFDFY"
     gene            complement(5286..6359)
                     /locus_tag="VQ543_001094"
     CDS             complement(5286..6359)
                     /locus_tag="VQ543_001094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001273827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2974 domain-containing protein"
                     /protein_id="HET2611825.1"
                     /translation="MANIFDYLKDVAYDSYYDLPLNELDILTLIEITYLSFDNLVSTL
                     PQRLLDLAPQVPREPTMLTSKNRLQLLDKLAQHKRFKNCKLSHFINDIDPELQKQFAA
                     MTYRVSLDTYLIVFRGTDDSIIGWKEDFHLTYMKEIPAQKHALRYLKNFFAHHPKQKV
                     ILAGHSKGGNLAIYAASQIEQSLQNQITAVYTFDAPGLHQELTQTAGYQRIMDRSKIF
                     IPQGSIIGMMLEIPAHKIIVQSTALGGIAQHDTFSWQIEDKHFVQLDKTNSDSQQVDT
                     TFKEWVATVPDEELQLYFDLFFGTILEAGISSINDLASLKALEYIHHLFVQAQSLTPE
                     ERETLGRLTQLLIDTRYQAWKNR"
     gene            6515..7192
                     /locus_tag="VQ543_001095"
     CDS             6515..7192
                     /locus_tag="VQ543_001095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000548969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET2611826.1"
                     /translation="MHKILLIEDDQVIRQQIGKMLSEWGFEVVLVEDFMEVLSLFVQS
                     EPHLVLMDIGLPLFNGYHWCQEIRKISKVPIMFLSSRDQAMDIVMAINMGADDFVTKP
                     FDQQVLLAKVQGLLRRSYEFGRDESLLEYAGVILNTKSMDLHYQGQVLNLTKNEFQIL
                     RVLFEHAGNIVARDDLMRELWNSDFFIDDNTLSVNVARLRKKLEEQGLVGFIETKKGI
                     GYGLKHA"
     gene            7185..8159
                     /locus_tag="VQ543_001096"
     CDS             7185..8159
                     /locus_tag="VQ543_001096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HET2611827.1"
                     /translation="MLDWKQFFLAYLRSRSRLFIYLLSLAFLVLLFQFLFASLGIYFL
                     YFFFLCCFVTILFFTWDILVEMQVYRQELLYGEREAKSPLEIALAEKLEAREMELYQQ
                     RSKAERKLTDLLDYYTLWVHQIKTPIAASQLLVAEVVDRQLKQQLEQEIFKIDSYTNL
                     VLQYLRLESFHDDLLLKQVQIEDLVKEIIRKYALFFIQKGLNVNLHDLDKEIVTDKKW
                     LLVVIEQIISNSLKYTKEGGLEIYMDDQELCIKDTGIGIKNSDVLRVFERGFSGYNGR
                     LTQQSSGLGLYLSKKISEELGHQIRIESEVGKGTTVRIQFAQVNLVLE"
     gene            complement(8208..10151)
                     /gene="thrS"
                     /locus_tag="VQ543_001097"
     CDS             complement(8208..10151)
                     /gene="thrS"
                     /locus_tag="VQ543_001097"
                     /EC_number="6.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000608363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine--tRNA ligase"
                     /protein_id="HET2611828.1"
                     /translation="MINITFPDGAIREFESGVTTFEIAQSISNSLAKKALAGKFNGKL
                     IDTTRAITEDGSIEIVTPDHGDALPILRHSAAHLFAQAARRLFPDIHLGVGPAIEDGF
                     YYDTDNTAGQISNEDLPRIEEEMQKIVKENFPSIREEVTKDEAREIFKNDPYKLELIE
                     EHSEDEGGLTIYRQGEYVDLCRGPHVPSTGRIQIFHLLHVAGAYWRGNSDNAMMQRIY
                     GTAWFDKKDLKNYLQMREEAKERDHRKLGKELDLFMISQEVGQGLPFWLPNGATIRRE
                     LERYIVNKELASGYQHVYTPPLASVELYKTSGHWDHYQEDMFPTMDMGDGEEFVLRPM
                     NCPHHIQVFKHHVHSYRELPIRIAEIGMMHRYEKSGALTGLQRVREMSLNDGHLFVTP
                     EQIQEEFQRALQLIIDVYEDFNLTDYRFRLSLRDPQDTHKYFDNDEMWENAQTMLRAA
                     LDEMGVDYFEAEGEAAFYGPKLDIQIKTALGKEETLSTIQLDFLLPERFDLKYIGADG
                     EDHRPVMIHRGVISTMERFTAILIENYKGAFPTWLAPHQVTLIPVSNEKHVDYAWEVA
                     KKLRDRGVRADVDERNEKMQFKIRASQTSKIPYQLIVGDKEMEDETVNVRRYGQKETQ
                     TVSVDNFVQAILADIANKSRVEK"
     gene            complement(10209..10385)
                     /locus_tag="VQ543_001098"
                     /pseudo
     CDS             complement(10209..10385)
                     /locus_tag="VQ543_001098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166032.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MazG-like protein"
     gene            complement(10392..10532)
                     /locus_tag="VQ543_001099"
     CDS             complement(10392..10532)
                     /locus_tag="VQ543_001099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000422774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MazG-like protein"
                     /protein_id="HET2611829.1"
                     /translation="MELQELVERSWAIRQAYHELEVKHHDFKWTVEEDLLALSNDIGN
                     FQ"
     gene            complement(10963..11163)
                     /locus_tag="VQ543_001100"
     CDS             complement(10963..11163)
                     /locus_tag="VQ543_001100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001826938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2611830.1"
                     /translation="MRRFYSHLPYYLVILFFYWPLYELFLLVVSDPLTLKGLYINNLL
                     FFTPMVILIVSLLYSYRFRFSL"
     gene            11402..11947
                     /locus_tag="VQ543_001101"
     CDS             11402..11947
                     /locus_tag="VQ543_001101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001852743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HET2611831.1"
                     /translation="MKLAVIAANGQAGKAIVEEAVKRGHEVTAIVRSENKSQAESIIK
                     KDLFELTKDDLTGFDAVISAFGAYTPDTLPLHSKSIELFNQLLAGTQTRFLVVGGSGS
                     LYIDETKTTRLLDTPDFPEEFKSLAKAQADELDLLRTKNNLNWAFVSPAVDFIPDGEK
                     TGNYILAGEIFTTNEKRNKPD"
     gene            12173..12442
                     /gene="rpsO"
                     /locus_tag="VQ543_001102"
     CDS             12173..12442
                     /gene="rpsO"
                     /locus_tag="VQ543_001102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S15"
                     /protein_id="HET2611832.1"
                     /translation="MAISKEKKNEIIAQYARHEGDTGSVEVQVAVLTWEINHLNEHIK
                     QHKKDHATYRGLMKKIGRRRNLLAYLRKNDVNRYRELINSLGLRR"
     gene            13258..13872
                     /locus_tag="VQ543_001103"
     CDS             13258..13872
                     /locus_tag="VQ543_001103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000531723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CadD family cadmium resistance transporter"
                     /protein_id="HET2611833.1"
                     /translation="MGQTIISAIGVYISTSIDYLIILIILFAQLSQNKQKWHIYAGQY
                     LGTGLLVGASLVAAYVVNFVPEEWMVGLLGLIPIYLGIRFAIVGEDAEEEEEEIIERL
                     EQSKANQLFWTVTLLTIASGGDNLGIYIPYFASLDWSQTLVALLVFVIGIIIFCEISR
                     VLSSIPLIFETIEKYERIIVPLVFILLGLYIMYENGTIETFLIV"
     gene            complement(14164..14913)
                     /locus_tag="VQ543_001104"
     CDS             complement(14164..14913)
                     /locus_tag="VQ543_001104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-acyl-sn-glycerol-3-phosphate acyltransferase"
                     /protein_id="HET2611834.1"
                     /translation="MFYTYLRGLVVLLLWSINGNAHYHNTDKIPNQDENYILVAPHRT
                     WWDPVYMAFATKPKQFIFMAKKELFTNRIFGWWIRMCGAFPIDRENPSASAIKYPINV
                     LKKSDRSLIMFPSGSRHSNDVKGGAALIAKMAKVRIMPVTYTGPMTLKGLISRERVDM
                     NFGNPIDISDIKKMNDEGIETVANRIQTEFQRLDEETKQWHNDKKPNPLWWFIRIPAL
                     ILAIILAILTIIFSFIASFIWNPDKKREELA"
     gene            15046..17382
                     /locus_tag="VQ543_001105"
     CDS             15046..17382
                     /locus_tag="VQ543_001105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000360031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IC family P-type ATPase"
                     /protein_id="HET2611835.1"
                     /translation="MDKNKIMGLTQREIKERQAEGLVNDFTASASTSTWQIVKRNVFT
                     LFNALNFAIALALAFVQAWSNLVFFAVICFNAFSGIVTELRAKHMVDKLNLMTKEKVK
                     TIRDGQEVALNPEELVLGDVIRLSAGEQIPSDALVLEGFAEVNEAMLTGESDLVQKEV
                     DGLLLSGSFLASGSVLSQVHHVGADNYAAKLMLEAKTVKPINSRIMKSLDKLAGFTGK
                     IIIPFGLALLLEALLLKGLPLKSSVVNSSTALLGMLPKGIALLTITSLLTAVIKLGLK
                     KVLVQEMYSVETLARVDMLCLDKTGTITQGKMQVEAVLPLTETYGEEAVASILTSYMA
                     HSEDKNPTAQAIRQRFQGQVVYPMLSNLPFSSDRKWGAMELEGLGIVFLGAPEMLLDS
                     EVPEAREALERGSRVLVLALSQEKLDHHKPQKPSDIQALALLEILDPIREGAAETLNY
                     LRSQEVGLKIISGDNPVTVSSIAQKAGFADYHSYVDCSKITDEELIALAEETAIFGRV
                     SPHQKKLIIQTLKKAGHTTAMTGDGVNDILALREADCSIVMAEGDPATRQIANLVLLN
                     SDFNDVPEILFEGRRVVNNIAHIAPIFLIKTIYSFLLAVICIASALLGRSEWILIFPF
                     IPIQITMIDQFVEGFPPFVLTFERNIKPVEPNFLRKSMLRALPSALMVVFSVLFVKIF
                     GTSQGWSELEISTLLYYLLGSIGFLSVFRACMPFTLWRVLLIVWSVGGFLATALFPRI
                     QKLLEISTLTEQTLPVYGVMMLVFTVIFILTSRYQARK"
     gene            17484..18161
                     /locus_tag="VQ543_001106"
     CDS             17484..18161
                     /locus_tag="VQ543_001106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000624068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenine-N(1))-methyltransferase"
                     /protein_id="HET2611836.1"
                     /translation="MISKRLELVASFVSQGAILLDVGSDHAYLPIELVERGQIKSAIA
                     GEVVEGPYQSAVKNVEAHGLKEKIQVRLANGLAAFEETDQVSVITIAGMGGRLIARIL
                     EEGLGKLANVERLILQPNNREDDLRIWLQDHGFQIVAESILEEAGKFYEILVVEAGQM
                     KLSASDVRFGPFLSKEVSPVFVQKWQKEAEKLEFALGQIPEKNLEERQVLVDKIQAIK
                     EVLHVSK"
     gene            18148..18945
                     /locus_tag="VQ543_001107"
     CDS             18148..18945
                     /locus_tag="VQ543_001107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000881127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nif3-like dinuclear metal center hexameric
                     protein"
                     /protein_id="HET2611837.1"
                     /translation="MLASEVIHAYEAFCPQEFSMEGDSRGLQIGTLDKGIQRVMVALD
                     IREETVAEAIEKGVDLIIVKHAPIFRPIKDLLASRPQNQIYIDLIKHDIAVYVSHTNI
                     DIVENGLNDWFCQMLGIEETTYLQETGPERGIGRIGNIQPQTFWELAQQVKQVFDLDS
                     LRMVHYQENDLQKPISRVAICGGSGQSFYKDALAKGADVYITGDIYYHTAQDMLSDGL
                     LALDPGHYIEVLFVEKIAALLTQWKEKKGWELEILPSQASTNPFRHI"
     gene            18962..20065
                     /locus_tag="VQ543_001108"
     CDS             18962..20065
                     /locus_tag="VQ543_001108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding oxidoreductase"
                     /protein_id="HET2611838.1"
                     /translation="MKKVAIIGAGIVGATAAYYLSRESDLEVTVFDHEQGQATKAAAG
                     IISPWFSKRRNKAWYKMARLGADFYVDLLADLEKSGQKIDFYQRSGVFLLKKDESKLE
                     ELYQLALQRREESPLIGQLAILDQASANELFPGLQGFDRLLYASGGARVDGQLLVTRL
                     LEASHVKLVKEKVTLTPLASGYQIGEEEFEQVILATGAWLGDMLEPLGYEVDVRPQKG
                     QLRDYQLVQDMEAYPVVMPEGEWDLIPFAGGKLSLGATHENDMGFDLTVDETLLQQME
                     EATLTHYLILAEATSKSERVGIRAYTSDFSPFFGQVPDLTGVYAASGLGSSGLTTGPI
                     IGYHLAQLIQDKELTLDPENYPIENYVKRVKSE"
     gene            20072..20263
                     /locus_tag="VQ543_001109"
     CDS             20072..20263
                     /locus_tag="VQ543_001109"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2611839.1"
                     /translation="MKIKEQTRKLAAGYSKHCFEVVDRTDEVSSKHCFEVVDRTDEVS
                     NHTHGKATLTWFELDFRRV"
     gene            20366..21385
                     /gene="galE"
                     /locus_tag="VQ543_001110"
     CDS             20366..21385
                     /gene="galE"
                     /locus_tag="VQ543_001110"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HET2611840.1"
                     /translation="MQEKILVTGGAGFIGTHTVIELIQAGHQVVVVDNLVNSNRKSLE
                     VVERITGVEIPFYEADIRDTATLRDIFKQEEPTGVIHFAGLKAVGESTRIPLAYYDNN
                     IAGTVSLLKAIEENNCKNIIFSSSATVYGDPHTVPILEDFPLSVTNPYGRTKLMLEEI
                     LTDIYKADSEWNVVLLRYFNPIGAHESGDLGENPNGIPNNLLPYVTQVAVGKLEQVQV
                     FGDDYDTEDGTGVRDYIHVVDLAKGHVAALKKIQKGSGLNVYNLGTGKGYSVLEIIQN
                     MEKAVGRPIPYRIVERRPGDIAACYSDPAKAKAELGWEAELDITQMCEDAWRWQSKHP
                     NGFED"
     gene            21387..22340
                     /locus_tag="VQ543_001111"
     CDS             21387..22340
                     /locus_tag="VQ543_001111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014632375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HET2611841.1"
                     /translation="MMISIIVPCLNEEEVLPLFYQALEALLPDLETEIEYVFVDDGSS
                     DGTLELLKAYREQNPAVHYISFSRNFGKEAALYAGLQYATGDLVVVMDADLQDPPSML
                     FEMKNVLDKNVDLDCVGTRRTSREGEPFFRSFCAVLFYRLMQKISPVALPSGVRDFRM
                     MRRSVVDAILSLTESNRFSKGLFAWVGFKTYYLDYPNVERQAGKTSWSFRKLFFYSIE
                     GIINFSDFPLIIAFVAGLLSCFLSLLMTFFVVVRTLILGNPTSGWTSLMAVILFLGGI
                     QLLTIGILGKYISKIYLETKKRPLYLIKEKSDDRLKKIEFI"
     gene            22492..23157
                     /locus_tag="VQ543_001112"
     CDS             22492..23157
                     /locus_tag="VQ543_001112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000949235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2611842.1"
                     /translation="MLSKEDYTEEIGLIKKQNYVEAELYPIVADIIKPTLKDSLSKRY
                     VFGRQRRGLGQIYYGLSNFPDIVILDKTYENKSRKSIKIEEWKKLRGCVEVKNLNYSL
                     ITEEKIKSTISNSFEHITGEMEQLTGEMGQLIGDLLWYKKVIYTNGIEWRFLSLDDKE
                     EIDNTIVEVVNKRIETEEAGNSFDWWKNIKDLSFNYTDICLSKDCRQEWNEFVKRVKE
                     IEW"
     gene            23196..23297
                     /locus_tag="VQ543_001113"
                     /pseudo
     CDS             23196..23297
                     /locus_tag="VQ543_001113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677122.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="group 2 glycosyl transferase"
     gene            complement(23348..23554)
                     /locus_tag="VQ543_001114"
     CDS             complement(23348..23554)
                     /locus_tag="VQ543_001114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001843159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="HET2611843.1"
                     /translation="MKITLIPERCIACGLCQTYSDLFDYHDNGIVRFYDDPDQLEKEI
                     SPSQDVLEAVKNCPTRALIGNQEA"
     gene            23606..24082
                     /locus_tag="VQ543_001115"
     CDS             23606..24082
                     /locus_tag="VQ543_001115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM domain-containing protein"
                     /protein_id="HET2611844.1"
                     /translation="MAKEPWQEDIYDQEESRAERRHRNHGGADRMANRILTILASIFF
                     VIVVVMVIVLIYLSSGGSNRTAALKDFHDSDASVVQISSSSSSQPEQSSEPESTSSSS
                     EEAANPEGTIKVLAGEGEAAIAARAGISIAQLEALNPGHMATGSWFANPGDVIKIK"
     gene            24091..24762
                     /locus_tag="VQ543_001116"
     CDS             24091..24762
                     /locus_tag="VQ543_001116"
                     /EC_number="2.7.4.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000849376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(d)CMP kinase"
                     /protein_id="HET2611845.1"
                     /translation="MKTIQIAIDGPASSGKSTVAKIIAKDFGFTYLDTGAMYRAATYM
                     ALKNQLGVEEVEALLALLDQHPISFGRSETGDQLVFVGDVDITHPIRENEVTNHVSAI
                     AAIPEVREKLVSLQQEIAQQGGIVMDGRDIGTVVLPQAELKIFLVASVDERAERRYKE
                     NIAKGIETDFETLKKEIAARDYKDSHRETSPLKQAEDAVYLDTTGLNIQEVVEKIKAE
                     AEKRM"
     gene            24893..25231
                     /locus_tag="VQ543_001117"
     CDS             24893..25231
                     /locus_tag="VQ543_001117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002920966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkylphosphonate utilization protein"
                     /protein_id="HET2611846.1"
                     /translation="MNNLPNCPKCNSEYVYEDGALLVCPECAHEWNPAEVAEVEEGLV
                     AIDANGNKLADGDTVTLIKDLKVKGAPKDLKQGTRVKNIRIVEGDHNIDCKIDGFGAM
                     KLKSEFVRKI"
     gene            25234..25863
                     /locus_tag="VQ543_001118"
     CDS             25234..25863
                     /locus_tag="VQ543_001118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000033944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Pr6Pr family membrane protein"
                     /protein_id="HET2611847.1"
                     /translation="MSKHYKLVFYSRIFLFLAAFTGVYLEITKHGGFGMLLYYTVLSN
                     LLVTIFTLYLLKVMSRVGENWQRPSLLRLKGGVTMSIMITCVIYHFLLAPIATNFYTL
                     ENFLCHYIVPIWFLADTLFFDKQGQYKIWDPAVWTILPFLYMMFALFNGLVLKLNIPN
                     AKDNPFPYFFLNVNKGWNVVFKWCLIIFVAYMVAGFIFYFIKQIKRKSS"
     gene            26103..27254
                     /locus_tag="VQ543_001119"
     CDS             26103..27254
                     /locus_tag="VQ543_001119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HET2611848.1"
                     /translation="MKQFLERASILALSLVLITSFSISSALPAMFDYYQGYSKEQIEL
                     LVSLPSFGIMMMLLLNGFLEKIFPERLQISLGLLILSLSGTAPFWYQAYPFVFGTRLL
                     FGLGLGMINAKAISIISERYQGKRRIQMLGLRASAEVVGASLITLAVGQLLAFGWTAI
                     FLAYSAGFLVLPLYLLFVPYGKSKKEVKKRAKEASRLTREMKGLIFTLAIEAAVVVCT
                     NTAITIRIPSLMVERGLGDAQLSSFVLSIMQLIGIVAGVSFSFLISIFKEKLLLWSGI
                     TFGLGQIVIALSSSLWVVVAGSVLAGFAYSVVLTTVFQLVSERIPAKLLNQATSFAVL
                     GCSFGAFTTPFVLGAIGLLTHNGMLVFSILGGWLIVISIFVMYLLQKRA"
     gene            27567..28316
                     /gene="truA"
                     /locus_tag="VQ543_001120"
     CDS             27567..28316
                     /gene="truA"
                     /locus_tag="VQ543_001120"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HET2611849.1"
                     /translation="MTRYKATISYDGYAFAGFQRQPHARSVQEEIEKTLTRLNKGQAI
                     TVHGAGRTDSGVHALGQVIHFDLPYQMDEEKLRFALDTQSPEDIDVISIELVADDFHC
                     RYAKHSKTYEFTVDRGRPKNPMRRHYATHFPYPLDVERMQIAIKKLEGTHDFTGFTAS
                     GTSVEDKVRTITEASLIVDETGQFLTFTFSGNGFLYKQIRNMVGTLLKIGNNRMPVEQ
                     IDLILEKKDRQLAGPTAAPNGLYLKEIRYEE"
     gene            28306..29079
                     /locus_tag="VQ543_001121"
     CDS             28306..29079
                     /locus_tag="VQ543_001121"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HET2611850.1"
                     /translation="MKNNRILALSGNDIFSGGGLSADLATYTLNGLHGFVAVTCLTAL
                     TEKGFEVFPTDDTIFQHELDSLRDVEFGGIKIGLLPTVSVAEKALDFIKQRPGVPVVL
                     DPVLVCKETHDVAVSELCQELIRFFPYVSVITPNLPEAELLSGQEIKTLEDMKTAAQK
                     LHDLGAPAVIIKGGNRLSQDKAVDVFYDGQTFTILENPVIQGQNAGAGCTFASSIASH
                     LIKGDKLLPAVESSKAFVYRAIAQADQYGVRQYEANKNN"
     gene            29057..29518
                     /locus_tag="VQ543_001122"
     CDS             29057..29518
                     /locus_tag="VQ543_001122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HET2611851.1"
                     /translation="MKQTKTTKIALVSLLTALSVVLGYFLKIPTPTGILTLLDAGVFF
                     AAFYFGSREGAVVGGLASFLIDLLSGYPQWMFFSLVNHGLQGFFAGFKGKSQWLGLIL
                     ATIAMVGGYALGSTLMNGWAAALPEILPNFMQNMVGMIVGFILSQSIKKIK"
BASE COUNT         8735 a         5371 c         6699 g         8992 t
ORIGIN      
        1 taaattttta gattgtggaa tttttttcaa cttaattctt gatttttttt ctaaattgtt
       61 atatacttaa tttacgggat aacagaatcc cgtcagaaag gggtgataat atgggaaaag
      121 agaatgttag aatgcgttta gcgtctgaat ccagacagat attagataag cttaaagatg
      181 atgtttacaa taaattaggc tatgaagtaa gctattccag tattgttagt caagctgtta
      241 gagaatacgt tcctaaaaaa gaacgtatag attggataaa attaaaagag acagctatac
      301 ctttttcatc gttaaaacag agcaataatt gggagtacca gacatcactt atgttagaga
      361 aagatgtatt aatcttactg tctgaactac aaaatttttt cttagatgtc ttccaagcga
      421 aacgtataca tagggcattt tgtatacgtc tatgtttgag agcgcaattt ttattaagta
      481 ataatgattc ttaatactat caatattaat gcggagtgta atgctccgca aaaataaaac
      541 ctattacggg ataaaaacac tactttattt aggatggaaa taagaacgta ttttttacta
      601 atattgttta gaaaggagtt tctttatgac accagaagaa caaactgctt tggaatactt
      661 ttatgaggaa ctcgagagtt acggtgaaga tgagcaagga gaggtctttg atttgtatga
      721 taattaaatc atctccatag tttctgagaa taattgagaa actatactct aaatcatagg
      781 tttatgtaaa gctagatata cacaaaagga ggtacgaatg aagatgaaag ctagagcttc
      841 accgttgaat tgattttgtt tctagaaaaa atcaataatt agaaaaatac gaggtaaaaa
      901 aatgaataga aatgtactaa attttctgcg aacagaaagt gctgaaagag ttagtcttta
      961 tatagacaag gctaatagat tggagggcga tgtaactcta ctcgcaccta gttctcaaga
     1021 tttggaagat attaaaaatg ctatgttttc caatcctaat ctcgagctaa aagtagcgag
     1081 actggatgtg atgaagaaaa tagcatatgc ttctacaaga aatcattatt taacaggggc
     1141 tacgattttt ggggatattt cgaaaggaac atacaattgt gatcctaaaa gttatgtcta
     1201 atataaggga ggttaatccc tccccttgtt tttgaaaatc gaaaggaaaa gtataaaaat
     1261 gaaagttaat gaatatttct ggagaacgag ctgtcttata ctaaaaaaga agaaatcgat
     1321 aaaatagtat acgtgttaga gatgtgtttg tcgtaaaagt ctggatagtt ttctcttagg
     1381 tagtcagctg tcatataata aaaagtagaa tggcaagcag tgatgattgg cataagagat
     1441 gaaaaacgct gagaactaat gaaggctaag agaacaaaaa atagaaaatc aatggtgaga
     1501 acccctaaat agtagaagcg aatcttttta ttgatttgag gataaatctc agcgaattga
     1561 tgtttgagtc ggacgaccaa gagaaatagc aggagtcctt gagcaaggaa gaaaattaaa
     1621 ccagagagca agagccactc aaaagatgtc tcgagtctag tgataaaaaa tgcaaatagt
     1681 agcaaatcaa taactgcaat tgctataaaa tggattctat agagtttttt catgacaaga
     1741 cctccctctt ttatctaact tcattctact ctaaaagaat gggagttaca actaaaatga
     1801 taaaaatagc agaggggaga ttctcttaag ttggctagta ttctttattt gagtttcctt
     1861 ctattatcta acttcttcat cattccagac aaataaagct ccgattgcat tgaggatata
     1921 aaagatgtat ttaccgatat tggcgaagtt tccttgaata ccagcttttg tcagctgaac
     1981 gaaattgtaa atcaaccaaa agccccactg tccctcattg ccaatgcatt caaagcattg
     2041 gcaatgaggg acagtgcaaa ggcaatagtt gttacgtagg caaggagatt catcttgccc
     2101 ccatatccga tatagttggt cacaaaggca aagaggaagg cgatgatgga aatgatgatg
     2161 gccgccaatt ttacctgttt ttggctcatt tggttgggtc tgccttcttg cgaagctttc
     2221 catttcttta tagcaaaggt ataaatgagg aaggtgacgg gataggtaat gatggccgcc
     2281 ttatttccaa ggatataatc aatagcaccg gacaaaatgg tattaacaat accaaagtaa
     2341 ttttcccatt tgcttaattt ccccgtgaaa cgagtggaca acatggaaat cccaacgttg
     2401 gttacggaaa tcaatccaaa gggtacaaga gctgtccatg gtccccagtc tacaaattta
     2461 tcgaggcgtg agttgaggta accagatgca atcgcaatcc aacgaccaaa gcaaccccga
     2521 agaggtcaaa ctatttagat gtagcaaaaa tttttagtga ttttttcata ggttaaacta
     2581 cctttctttt tttcaaatat tctcccattt tttttcaaat attctaccac caaatgaaag
     2641 taaaataaaa tgatagaaat aaaaccctga aaataaaact ttcagggttg gtaggggact
     2701 tgagaaatta gttgattttc tcgacataga gttgttttgc aatgtccata ttcacttgta
     2761 aatcctcgtc gttactgagg atagtgaagg tattgctgaa gccatcaaac tgcttaactt
     2821 ggagctggtc accgatgtga agtgagtgct tgtccagata atggagaatg tcaaaactat
     2881 cgtgcatccg agtcaggcgg taggcgccag cttccttgat atcagctagt gggaggttat
     2941 tgatttcaac gaggagttct cccttggcag gaatagttcc tccgtggggg caggttttag
     3001 ggaaacctag cagtttatct agtctttcca cgaacaggtc agagacagtg tgttccaaga
     3061 cctcagcttc ctcgtgaatc tggtcacttg tatagtctaa atgatgaact agaaaaactt
     3121 caatcaagcg gtgcttacga tagagctcag agaccagttt gagaccgagg tcagtcagta
     3181 gatagccaca ttccttgtcc tttaggatga gattttcact tttcattcgt ttgatcattt
     3241 cagttacggc agggggagag acttgcatgc gagccgcaat ttccttgttg gtaatcttat
     3301 gcaggtctat gccaatttca taaatacatt ttagatagtc ttctttgttt ggggtcattc
     3361 gtttcctctt gtctaatatc tttatctagt atatcaaaaa aagctagatt tctctagctg
     3421 tgacttttta tgttatactt attgcaagag aaaaaacgag gagatggata tgacgaaaat
     3481 agctcttctt tcagatattc atggaaatac caccgccttg gaggctgttt tggcagatgc
     3541 tcggcagcta ggagtggatg aatactggct tttgggagat attctcatgc cagggacagg
     3601 gcgtagaagg attttggact tgttggatca actaccgatt acggctagag ttttgggaaa
     3661 ctgggaagac agtctttggc atggtgtccg taaggaattg gatagtactc gccctagtca
     3721 acgctatctc ttgcgccagt gccagtatgt tttagaggaa atttccctag aagaaattga
     3781 agtgctccac aatcaacctc ttcaaattca tcgtcagttt ggggatttga cagtgggaat
     3841 tagccatcat ctgcctgata agaactgggg gcgagagttg attcatactg gcaaacaaga
     3901 ggaatttgac cgcttggtga ctcatcctcc ctgtgatatt gctgtttatg gacacattca
     3961 ccagcagttg cttcgttacg ggactggtgg gcaattgatt gtcaatccgg gttcgattgg
     4021 ccaacctttc tttttggacg ctcagctacg gaaggacttg cgggcccagt atatgatttt
     4081 ggagtttgat gacaagggcc tggtagatat ggacttccga cgggtagatt acgatgtggc
     4141 agctgaattg cagctggcta aagacctgag acttccctat tttgaggttt actatgaaag
     4201 tctggtcaat gggatccacc atactcatca tcaggaattt ttgagagaat tggctcagaa
     4261 agagggttgc gatcgggagt tagacgactg gttgaaaagt ggtaacgatt gacattacaa
     4321 ctaaaaaggg tataataata gaaaaagaag agtagaggca gggtagcctc gtaaaaagga
     4381 gaagaggatg caaattccaa gtagatttac cattgcgact catatgctga taatcattgc
     4441 cctcgagggg aagaaaagca aggtgaccag tgattttctg gctgctagtg tcggggtcaa
     4501 tcctgtcatt atcagaaaga tcttgtccca gttgaagaag gcagagctga tttcagtagc
     4561 gcgtggaacg ggcggaacag atattgtcaa ggaccttaag gatattagtc ttttagatgt
     4621 ttatcaggcg gtcgaatgtc ttggtaagac aggtcaactc ttcagtttcc atgacaatcc
     4681 gaatccaaat tgccctgtag gagctcatat tcatgatgtt ttggatcaaa aattggagag
     4741 aattcagttg actatggagg cagaacttgg tcaaaccagt ctagaaaaag tcgtggccga
     4801 tgcagagagt cagatgaagg attaagaggg ataaatgccc tcttttttct ttggataatt
     4861 atgataaaat gtagctatta aaggagtaag aaatgtatct cgttatagga attgtattag
     4921 cctttatagt gtcattttgg aaggataata gaagtttgtg gaatccagta ttatttttat
     4981 tatccctcat ttcaagttat ttttatctat cctacctttt ttataaaaat ggatacgaga
     5041 atgttcagtt agctttttat gtatttgcct ttgtcttact tccttttttg ctttttctaa
     5101 gtggcatctt tttaatctat aatggggtca ttttgttgaa gcgagaggga cgttccaagc
     5161 cccattatct ctcaatgctc tttgattttt attgactatt agattctatt taaaaagact
     5221 tagaatgcac atgaaagtat gtattctagg tcttttgttt tgtatacatt taattttcaa
     5281 gagtattatc tatttttcca tgcctggtaa cgagtatcaa tcaataactg ggtaaggcga
     5341 cccaaggttt ctctttcttc tggagtgagg gattgagctt ggacaaagag atgatgaatg
     5401 tattcaagcg cctttaagga agccaagtca ttgatagagc taataccagc ctcaagaata
     5461 gtgccaaaga agaggtcgaa gtagagctga agttcttcgt cagggactgt ggccacccat
     5521 tctttaaagg ttgtgtctac ttgctggcta tcactgttgg tcttatccag ttggacgaag
     5581 tgcttgtcct caatctgcca actaaaggta tcgtgctggg cgatgccacc cagggcagta
     5641 ctctgaacga tgattttgtg agcaggaatt tccagcatca taccgataat ggaaccttgt
     5701 ggaatgaata tcttgcttct atccattatc ctttgataac ccgcagtctg tgtcaattct
     5761 tgatggagac caggtgcatc aaatgtataa actgctgtga tctgattttg caaactttgc
     5821 tcaatttggc tagcagcata gatagcgaga tttcctccct tggaatgccc agctagaata
     5881 accttttgct taggatgatg ggcaaaaaag ttctttaaat agcgaagggc gtgcttttga
     5941 gcaggaattt ccttcatata ggtcaggtgg aaatcttcct tccagccaat gatactgtca
     6001 tctgtcccac gaaagacaat cagataggta tcgaggctga cacgataagt catagccgca
     6061 aattgctttt gcagttcagg gtcgatgtcg ttgataaaat gggagagttt gcaatttttg
     6121 aagcgcttgt gttgagccaa tttatctaat aattgaaggc gatttttgct agtaagcatg
     6181 gtgggctctc ttggaacctg aggtgctaga tctaaaagac gttgaggaag tgtggagacc
     6241 agattatcaa aggagaggta ggtgatttct attaaggtta gaatgtctaa ctcattcaag
     6301 ggaaggtcgt aataagaatc atatgcgaca tctttcagat agtcaaaaat attggccata
     6361 agagctcctt tctttttatt tatcttagca aatttccctc aaattagcta gtagcatagc
     6421 ctgtttgcac tggctaaaaa caggctattt caaattcagt ttcagaccat ctagcatgga
     6481 aaaatctgtt ataataatgg aaaaggagaa gcgcatgcac aagattttat taatagaaga
     6541 tgatcaggtc attcgtcaac agattgggaa aatgctctct gaatggggat ttgaagtggt
     6601 cctggtagaa gactttatgg aagttttgag tctatttgtt cagtcggaac ctcatctggt
     6661 cctcatggat attggtttgc ccttgtttaa tggttatcac tggtgtcagg aaatccgcaa
     6721 gatttccaag gtacctatca tgtttctttc ttcgagagac caggctatgg atattgtcat
     6781 ggcaatcaat atgggggcgg atgactttgt gaccaagcct tttgaccagc aggttctttt
     6841 agctaaggtt cagggcttgt tgcgtcgttc ctatgagttt gggcgtgatg agagtttgct
     6901 ggaatatgct ggtgttatcc tcaataccaa atccatggat ttacattatc aagggcaagt
     6961 cttgaatttg accaagaatg aattccagat tttacgcgtg ttatttgagc atgcaggcaa
     7021 catcgtagca cgtgacgacc tgatgcggga actttggaac agtgactttt tcattgatga
     7081 taataccctc tctgtcaatg tggctcgttt gcgtaaaaag ttggaggagc agggattggt
     7141 aggatttatc gagaccaaga aaggaatagg gtacggattg aagcatgctt gattggaaac
     7201 aattttttct agcctatctg cgctcccgta gtcgtctttt tatctatctg ctttctttgg
     7261 catttcttgt cttactcttt cagtttttat ttgccagtct aggaatttac ttcctctact
     7321 ttttcttctt gtgttgcttt gtaaccatct tatttttcac ttgggacata ttggtggaaa
     7381 tgcaggtcta tcgccaggaa cttctctatg gagagaggga agccaagtct cctttggaaa
     7441 tagctttagc agaaaaatta gaagcgcgtg agatggaact ctatcagcag aggtcaaaag
     7501 cagaaagaaa actgacggat ttgctggatt actatacctt gtgggtccat cagataaaga
     7561 cccccattgc agccagtcaa ctcttagttg cagaagtggt cgaccgccaa ctgaagcagc
     7621 agctagaaca ggaaattttc aaaatcgact cttataccaa cctagtttta cagtacctgc
     7681 gtttagaaag tttccatgat gatttgctct taaagcaggt tcaaattgag gacttggtca
     7741 aggaaataat tcgtaaatat gctcttttct ttattcaaaa aggcttaaat gtcaatctac
     7801 atgaccttga taaagaaatc gtgacggata aaaagtggct gctagtggtt attgagcaaa
     7861 tcatctcaaa cagtctcaag tacaccaagg aaggtggtct ggagatttat atggatgacc
     7921 aagagctttg tatcaaagat acgggaatcg ggataaaaaa cagtgatgtc ctccgagtat
     7981 ttgaacgtgg cttttcagga tacaatggcc gtttgaccca gcagtcctct ggacttggcc
     8041 tttatctatc taagaaaatt tctgaagaac tggggcacca gattcgtatc gagtctgagg
     8101 tcggaaaagg aacgacagtg cggattcagt ttgctcaagt gaacttagtc cttgagtaaa
     8161 aatagatgag aaaaagcctc cagattggag gcttttatgc tagactctta tttctcaacg
     8221 cgtgatttgt tggcgatatc agctaggata gcttgaacaa aattatcaac tgagacagtt
     8281 tgtgtttctt tttggccgta gcgacgaacg ttgactgttt cgtcttccat ttctttgtct
     8341 ccaacaatta attggtaagg aatcttgctg gtttgtgaag cacggatctt gaactgcatt
     8401 ttttcattgc gctcatctac gtctgcacgg acaccgcggt cacggagttt cttggctact
     8461 tcccaagcgt agtccacgtg tttttcgtta gatactggga tgagggttac ttggtgtggt
     8521 gccagccatg ttgggaaggc ccccttgtag ttctcaatca agatagctgt gaagcgttcc
     8581 atagttgaga taaccccacg gtggatcatg actggacggt gatcttcgcc atcagctccg
     8641 atgtatttga ggtcgaagcg ttctggcaac aagaaatcaa gttggatagt agaaagggtt
     8701 tcttcttttc caagggcagt tttaatctgg atatccaatt ttggtccgta gaaggctgct
     8761 tcaccttcgg cttcaaagta gtccacgccc atttcatcaa gagctgcacg aagcatggtt
     8821 tgggcatttt cccacatctc atcgttatca aagtacttat gagtatcttg agggtcacga
     8881 agagagaggc ggaagcggta gtcagtcaag ttgaagtctt cataaacatc gataatcaac
     8941 tgaagggcac gttggaattc ttcttggatt tgttctggag taacgaatag gtgaccgtcg
     9001 ttgagtgaca tttcacgtac acgttgaagg ccagtgaggg caccagattt ttcgtaacgg
     9061 tgcatcatac cgatttcagc gatacggatt ggcaattcac ggtaagagtg aacatggtgt
     9121 ttgaaaactt ggatgtggtg cggacagttc attggacgaa ggacaaattc ttccccgtca
     9181 cccatgtcca tggttgggaa catgtcttct tggtaatgat cccagtgacc agaagtcttg
     9241 taaagctcaa cagaagcaag tggtggagtg tagacgtgtt ggtagccaga agccaactct
     9301 ttgtttacga tgtagcgttc caattcacga cggatagtcg caccatttgg caaccagaat
     9361 ggcaaacctt gtcccacttc ttgtgaaatc ataaagaggt caagctcttt accaagttta
     9421 cggtggtcac gttccttagc ttcttcacgc atttgaaggt agtttttcaa gtctttcttg
     9481 tcaaaccaag ctgtaccgta gatacgttgc atcatagcgt tgtcgctgtt tccacgccag
     9541 tacgcaccag ctacatggag aaggtggaag atttggatac gacctgttga tggaacgtga
     9601 ggtccacggc agaggtctac atattcaccc tgacgataga tagtcaaacc gccttcgtct
     9661 tctgagtgtt cttcaatcaa ttccaacttg taagggtcat ttttgaagat ttcacgtgcc
     9721 tcgtctttag tcacttcttc acgaatagat gggaagtttt ctttgacgat tttttgcatt
     9781 tcttcttcga tacgaggaag gtcttcgtta gagatttgac cagctgtgtt gtcagtatcg
     9841 tagtagaaac catcttcgat ggctggacca actcccaagt gaatgtctgg gaaaagacga
     9901 cgagctgctt gggcgaacaa gtgagctgct gagtgacgca agattggaag ggcatctccg
     9961 tgatcaggtg tcacaatttc gatgcttcca tcttcagtga tagcgcgagt agtgtcgatg
    10021 agtttgccgt tgaatttacc agccaaggct tttttagcta gggaattgct gatagattgg
    10081 gcaatttcaa aagttgttac gccagattcg aattcacgaa tagcgccatc tgggaaagta
    10141 atgttaatca tgatgttctc cttttttatt atttcatagt ttctaagcat tgatttttta
    10201 tcagcagact acttccaagt tctaacgttc aattgctttt ctttatcaga gaggaagttt
    10261 tccatttccg tcagaatatc tatatccaaa cgttgagaaa gttctaatag tcaccagata
    10321 ttttctgaaa gtttttgttc cagtgtgtag ggtgtttcat catagtagcg tccttgcttt
    10381 gtcatcacca gtcattggaa atttccaata tcattagata aagccaagag gtcttcttct
    10441 accgtccact tgaaatcatg atgcttaact tccagttcgt gataagcttg tcggattgcc
    10501 caactgcgct ccactaattc ttgcaactcc ataattagta tcctaataaa aaaatgcgac
    10561 atcctcgaaa ggacgtcgca acgtggttcc accttcattt atgtacctca aaagagaggg
    10621 acacctctga tcggctctaa cgtggccacc gttttatgtt ttcataaaaa actcaagagt
    10681 agtatcagtt tagacttcct atgcgtttcc agcaaccacg cactctctag tagaaaggga
    10741 ctaagtgact tgtctctatg gattattata gcatgattgt gagatttttc aaggattttg
    10801 tgaaagtttt ttgtttttca ttttttgtag aatatgcttg atgctaatac cagaatccat
    10861 gcccaccaga gcaactgttt catagattag caagtaaatt agtataaaca caccaaaggt
    10921 tatgatagta aagtaaaaga gcagtccgtt accaactaac catcaaagtg agaaacggaa
    10981 acggtagcta tagagtaacg atacaatcaa gattaccata ggtgtaaaga agagaagatt
    11041 gtttatatag agtcccttga gtgtaagggg gtcagaaaca actagcaaga acaactcata
    11101 aagtggccaa taaaagaata atatgaccag atagtagggg agatgggaat agaatctacg
    11161 catgataatc acctcgtttt aaaaaaacag acaacttaga tctcttgcta tgattattat
    11221 agtatgttta aaacaagaaa gtaaatttgt tgacaaagaa gatttttctt ttcactagaa
    11281 tcatggttag ttttcttggt agaaatattt tgataataat taagcaagac tattgacatt
    11341 gattattaag agtgtcacaa ttgttgtaac taaaataatt acaacaagag gggtataaaa
    11401 aatgaaacta gcagttattg cagcaaatgg acaagcgggg aaggcaattg ttgaagaagc
    11461 agtcaaacga ggacatgaag taacggctat tgttcgttct gaaaacaaaa gtcaagctga
    11521 gtctattatt aaaaaagatt tatttgagtt gacaaaagat gatcttactg gatttgatgc
    11581 tgttatttca gcgtttggtg cttatacacc agatacgcta ccgctccaca gcaaatcaat
    11641 cgaactattt aatcagcttc ttgctggaac acagacacgt tttctagttg tagggggatc
    11701 aggaagcctt tatatagatg aaacaaaaac gacacgactt ttagatacgc ctgattttcc
    11761 tgaagaattt aagtcactag caaaagctca agcggatgaa ttggatcttc ttcgtacaaa
    11821 aaataatctc aactgggctt ttgtcagtcc tgctgtagat tttattcccg atggtgaaaa
    11881 aacaggaaac tacattctag caggagaaat ttttactact aatgaaaaaa ggaataagcc
    11941 agattagtta tgcagattat gctattggat tggtagatga acttgaaaaa ggtcatcata
    12001 taaaagaacg tatctcttta cttgaaaaat aataactatg agagtattaa tgtttgacag
    12061 aaaatttaaa tcttggtaga atagggattg tcgtaaagac aaataacttc ttcttggtta
    12121 caggcatgcc aacctgtcac tcggatgaag ccaaataaaa aggagaaaca tcatggcaat
    12181 ctcaaaagag aaaaaaaatg aaatcatcgc acaatatgca cgtcacgaag gtgatacagg
    12241 ttcagtagag gttcaagttg ctgtccttac ttgggaaatc aaccacctta atgaacacat
    12301 caaacaacac aaaaaagacc acgctactta ccgtggattg atgaaaaaaa tcggtcgccg
    12361 tcgtaacttg cttgcatact tgcgtaaaaa cgacgttaac cgttaccgtg agttgatcaa
    12421 ctctctagga cttcgtcgct aattcaagat acaaaggctg tcaaaagcac aaagtaaaaa
    12481 taggaaaatt tacgaagaaa cttcagtttc taggagattt tatctttttt gccaagtgct
    12541 taggccgtgt tcaattgagc atatcttgat aatgaagcta ctctaaattg ggtagctttt
    12601 ttgtgttgtc accttacctc gatatactca agtataatct ttggttacgg ttcctagcac
    12661 tgtaaggtaa aataaaccag cttttctccc ttcggggaga ttttttttgt ttcactgaaa
    12721 gtttcgtacg atcttcgcct cgtcgcctag tctataaacg atttatctag caagaatcat
    12781 gatgctaagg gcgtcaaaaa tccgtatgaa aatagggaaa tgacacagtg ttcgatgagc
    12841 acaaggagtt tcatcttttt cactaggatt ttagcccgga ctcaaatcag ctctctgact
    12901 tcagagggct tttttattga ggttttatcg gtaacaattt tggagactac aaaaacctca
    12961 aacggtatca gctaattaca ccataaaggt gcgcagttac tcggcttttc aagccgagta
    13021 gttgtatgca agccccctag aagagcccac tctttacaaa gtaaagtata gtatgttata
    13081 ctttacatgg aagtagtcac tgaattccag ttagaaatta ctttgtaact acgttttgag
    13141 gaggagtaaa atgctttcct acgttcgata ttacccacta gcgatagcta aattaatgtg
    13201 tctgtgctct cctaaaatct gctgatttat tactgactaa tacaggagtt tttttttatg
    13261 ggacagacaa tcatatctgc tattggtgtt tatatttcca ccagtatcga ttatttaatt
    13321 attttaatta ttttatttgc acagctatca cagaataaac agaaatggca tatttatgcg
    13381 gggcaatatc taggcacagg cttacttgta ggggcgagtt tagttgctgc ttatgtcgtt
    13441 aatttcgtgc ctgaagaatg gatggttgga ttgcttggtt taatccctat ctatttaggg
    13501 attcgctttg caattgttgg agaagatgcg gaagaagaag aggaagaaat tattgaaaga
    13561 ttagaacaaa gcaaggcaaa tcaactgttt tggacagtta cattgctgac aattgcgtct
    13621 ggcggagata atttaggtat ctatatacct tattttgctt cgttagattg gtcacagacc
    13681 ctcgtggcct tgcttgtgtt tgtaatcggc ataattatct tttgcgagat tagtcgggtg
    13741 ttatcttcta ttccgttaat attcgagaca attgaaaaat acgagcgaat cattgtgccc
    13801 ttagtattca ttctacttgg actatacatc atgtatgaaa atggcacgat agagactttt
    13861 ctgatcgtgt agattttttt gtttcactag gattttagtc cgagctcaaa tcagctctct
    13921 gattttcaga gggctttttc attgagtata aatggacaat cttaaagtta ctctattgta
    13981 gagtggcttt tgatttgatt aggagattct tataaatata gtaaaatgaa ataagaatag
    14041 gacaaatcga tcaggacagt caaatcgatt tctaaaaatg ttttagaagt agaggtgtac
    14101 tattctagtt tcaatttgat atataaatga aaaccttagc tgtttggcca aggttcattt
    14161 cttctatgca agttcttctc ttttcttatc tgggttccag atgaagcttg cgataaagct
    14221 aaagatgatg gttaggatag cgagaataat agcaaggatg agggcaggga tgcggataaa
    14281 ccaccagagt ggatttggtt ttttatcatt gtgccattgt ttcgtttctt cgtccagacg
    14341 ttggaattct gtttgaatac gattggcgac tgtttcaatg ccttcatcat tcattttctt
    14401 gatatctgag atatcgattg gatttccaaa gttcatatcg acacgttcac ggctaatcaa
    14461 gcccttcaaa gtcatgggac cggtgtaggt aaccggcatg atacggacct tggccatttt
    14521 ggcaatcagt gctgcgcccc ccttgacatc gtttgagtgg cggctaccac ttggaaacat
    14581 gatgagagag cggtcacttt ttttgagaac gttgatagga tatttgatgg ctgaggcgct
    14641 gggattttca cggtcgatgg gaaaggcgcc acacatacga atccaccaac caaagatacg
    14701 gttggtaaag agttcttttt ttgccataaa gatgaactgt tttggcttgg tcgcaaaggc
    14761 catataaaca ggatcccacc aggtacggtg aggcgcaact aaaatataat tttcatcttg
    14821 attaggaatt ttatcagtat tatgatagtg agcattgcca ttgatggacc ataagagcaa
    14881 tacaactaat ccacgcaaat aagtataaaa catgcgatct ccttcgattg ttttcttgtt
    14941 attattatac cttatcaaag gagggctggc aaacttttcc cttgactaga tgcatatttg
    15001 ggatgaaatt agaattctgt taaaaaaaat gatataatag aatttatgga taaaaataag
    15061 attatgggat taacccaaag agaaatcaag gaaagacagg ctgagggttt ggtcaatgac
    15121 tttaccgcat cagccagtac cagcacttgg caaatcgtta aacgaaatgt ctttaccctt
    15181 tttaacgctt tgaactttgc cattgctttg gcccttgcct ttgtgcaggc ttggagcaat
    15241 ctggtcttct ttgctgttat ctgctttaac gctttttctg ggattgtgac cgagctacga
    15301 gccaaacaca tggtggacaa gctcaatctc atgaccaagg aaaaggtcaa aaccatccgt
    15361 gatggtcagg aagttgctct taatcctgaa gaattagtgc taggagatgt cattcgtttg
    15421 tctgcaggag agcagattcc tagtgatgcc ttggttttgg aaggctttgc ggaagtcaat
    15481 gaagccatgt taacgggaga aagtgatttg gtgcaaaagg aagttgacgg cttacttttg
    15541 tcaggaagtt tcctagccag tgggtcagtt ttatctcaag ttcaccatgt cggtgcagac
    15601 aactatgctg ccaaactcat gcttgaggct aagaccgtta aacccatcaa ctcccgtatc
    15661 atgaaatcgc tggacaagtt ggctggtttt actgggaaga ttatcattcc ctttggtctg
    15721 gctctcttgc tggaagcctt gcttttaaaa ggcctgcctc tcaagtcatc cgttgtaaac
    15781 tcgtcgacag ctcttttggg aatgttgcct aagggaattg cccttttgac cattacttcg
    15841 ctcttgactg cagtgattaa gttgggcttg aaaaaggtct tggtgcagga gatgtactct
    15901 gttgagacct tggcgcgcgt ggatatgctc tgtctggaca agacgggtac catcacccaa
    15961 ggaaagatgc aggtggaggc tgttcttcca ctgacggaaa cttatggtga agaggctgtt
    16021 gccagcatcc tgaccagcta tatggcccat agtgaggata aaaatccaac agctcaagcc
    16081 attcgccaga gattccaagg tcaagtagtc tatcctatgc tctctaatct tcccttctcc
    16141 agcgaccgca agtggggagc catggagtta gaaggtttgg gaatagtttt cttaggggca
    16201 cctgagatgt tgctggattc tgaggtccca gaagccagag aggccttgga gagaggatca
    16261 cgtgtcttgg tcttagctct cagtcaggag aaattagacc atcacaaacc acagaaacca
    16321 tctgatattc aggctctagc cttgctggaa atcttggatc ctattcgaga gggagcggca
    16381 gagacgctga actatctccg ttctcaggaa gtggggctca agattatctc tggtgacaat
    16441 ccagttacgg tatccagcat tgcccagaag gctggttttg cggactatca cagctatgtc
    16501 gattgttcaa aaatcacgga tgaggaattg attgctctgg cggaggagac agcgattttc
    16561 ggacgtgttt cccctcatca aaagaaactc attatccaaa cgctgaaaaa agcgggtcat
    16621 acaacagcta tgactgggga tggagttaat gatatcctgg ctcttcgtga ggcggattgt
    16681 tctatcgtaa tggcggaggg agacccggca acccgtcaga ttgccaacct ggttctcttg
    16741 aactcagact ttaatgatgt tcctgagatt ctttttgaag gtcgtcgtgt ggtcaataac
    16801 attgcccaca tcgctccgat tttcttgata aagaccatct attccttcct gttagcagtc
    16861 atctgtattg ccagtgcttt actaggtcgg tcagagtgga ttttgatttt ccccttcatt
    16921 ccgatccaga ttaccatgat tgaccagttt gtggaaggtt tcccaccatt cgttctgact
    16981 tttgagcgaa atatcaaacc tgttgagcca aatttcctca gaaaatccat gcttcgtgcc
    17041 ctaccaagtg ccctcatggt cgtgtttagc gttctttttg tgaaaatctt tggaacgagt
    17101 caaggttggt ctgagttaga aatctcaact ctcctctatt atctcttggg gtcaattggt
    17161 ttcttatccg tatttagagc ctgcatgcca ttcactctat ggcgagtcct cttgattgtc
    17221 tggtcagtag gaggcttcct agccacagct ctcttcccaa gaatccaaaa actgcttgaa
    17281 atttcaacct tgacagaaca aacgttgcct gtttatggtg tcatgatgtt ggtctttaca
    17341 gtgattttca tcctgactag tcgctatcaa gctagaaaat aaagaaagac tgcaatctgt
    17401 ggattgcagt ttttttaggt acaagattgc cagccgaaat gtggtataat aagaggtaat
    17461 agagttttgg aaagtgagag aagatgattt caaagagatt agaattggta gcttcctttg
    17521 tgtcacaggg ggctatttta ctagatgtgg gaagtgacca tgcttatctg cctatcgagt
    17581 tggttgagag aggccaaatc aaaagcgcta ttgcaggtga ggtggtggaa ggtccctatc
    17641 agtctgcggt taaaaatgtt gaggctcacg gcctaaagga gaaaatccaa gtccgtttag
    17701 ccaatggctt ggcagctttt gaagagactg accaagtgtc tgtcattacc attgctggca
    17761 tgggtggtcg tttgattgct aggattttag aagaaggttt ggggaagtta gctaatgtag
    17821 agcgtttgat cctccagccc aataatcgtg aagacgactt gcgtatctgg ctacaggatc
    17881 atggattcca gattgtagca gaaagcatct tagaagaagc tggaaagttt tatgagattt
    17941 tggtggtgga agcaggacaa atgaagctat cagccagtga tgttcgcttt ggtcccttct
    18001 tgtccaaaga agtcagtcca gtatttgtcc aaaaatggca aaaagaagct gagaagctag
    18061 agttcgctct cggacaaatc ccagaaaaaa atctggaaga acgtcaagtt ctagtagata
    18121 agattcaagc tatcaaggag gtgctccatg ttagcaagtg aagtgattca tgcttatgaa
    18181 gccttttgcc ctcaggaatt ttctatggag ggagacagcc gtggtctgca aattggcact
    18241 ttagacaagg gtatccaaag ggtcatggtt gccctcgata ttcgtgaaga gacagtggca
    18301 gaggccattg aaaagggtgt ggacttgatt atcgtcaagc acgcgcctat ctttcgtcct
    18361 atcaaggact tgcttgccag ccgtccgcaa aatcagattt acatcgacct gattaagcat
    18421 gacatcgcag tttatgtcag ccataccaat attgatatcg ttgaaaatgg gctcaatgac
    18481 tggttttgtc agatgctagg aatcgaggag acgacttatc tgcaggaaac aggtccagaa
    18541 cgtggaattg gacgtattgg gaatattcag cctcagacat tttgggaatt ggcccaacag
    18601 gtcaagcaag tctttgacct agatagcctt cgaatggtgc attatcaaga gaatgatttg
    18661 cagaagccta tttcaagagt agcaatttgt ggtggaagcg ggcagtcttt ctataaggat
    18721 gctttggcaa agggggcaga tgtctatatc actggtgata tctactacca tactgctcag
    18781 gatatgctgt ctgatggctt gttagcattg gatccaggtc actatatcga agtgcttttt
    18841 gtggaaaaaa tcgcagcact ccttactcaa tggaaagaga aaaaaggctg ggaactagag
    18901 attttaccta gtcaagcatc gaccaatcct ttccgtcata tctagttaga aagtgaagac
    18961 aatgaaaaaa gttgccatta ttggagcagg aattgtggga gcaacagctg cctactacct
    19021 ctcgagagaa agtgacctag aggtgaccgt ttttgaccat gagcaaggtc aagccaccaa
    19081 ggccgcagca ggaattatca gtccttggtt ttccaaacgc cgtaataaag cctggtacaa
    19141 gatggcgcgc ttgggggctg atttttatgt ggatttatta gctgatttag agaaatcagg
    19201 acaaaaaatc gacttttacc agcgttcggg agtctttctc ttgaaaaagg atgaatccaa
    19261 gttggaagaa ctttatcaac tggccctcca gcgcagagaa gaatctccct tgatagggca
    19321 attagccatt ctggaccaag cctcagctaa tgaattattc cctggtttgc agggatttga
    19381 ccgcctgctc tatgcttctg gtggagcgag agtagatggc caactcttgg taactcgtct
    19441 gctagaagcc agtcatgtca agctggtcaa agaaaaagtg actctgacac cgttagcatc
    19501 aggctaccag attggtgaag aggagtttga gcaggttatt ttggcgacgg gagcttggtt
    19561 gggggacatg ttagaaccct tgggttatga agtagatgtt cgtcctcaaa aaggacaact
    19621 acgagattat cagctggtcc aagacatgga agcttaccct gttgtcatgc cagaagggga
    19681 gtgggatttg attccttttg caggtgggaa attgtcctta ggcgctaccc acgaaaatga
    19741 catgggattt gatttgacgg tagatgaaac cttgctccaa caaatggagg aggccacctt
    19801 gactcactat ctgattttgg ctgaagctac ttcaaaatct gagcgtgttg gaatccgtgc
    19861 ctacaccagt gatttctctc ctttctttgg gcaggtgcct gacttaactg gtgtctatgc
    19921 agccagtgga ctaggttcat caggcctcac aactggtcct attattggtt accatttagc
    19981 tcaactgatc caagacaagg agttgacctt ggaccctgaa aactacccaa ttgaaaacta
    20041 tgtcaaacga gtaaaaagcg aataatactc aatgaaaatc aaagaacaaa ctaggaaact
    20101 agccgcgggt tactcaaagc actgctttga ggttgtggat agaactgacg aagtcagctc
    20161 aaaacactgt tttgaggttg tagatagaac tgacgaagtc agtaaccata cccatggcaa
    20221 ggcgacgttg acgtggtttg aattggattt tcgaagagta taagcatttt actgaaattt
    20281 tatcaggtag tttaggatgg caaatgacat tccctgtcaa aaatggtaaa ataagaaaaa
    20341 ataatctgag aatcgaggaa aaaagatgca agaaaagatt ttggtaactg gtggtgccgg
    20401 ttttattgga acccacactg ttattgaatt gatccaagca ggccatcaag ttgttgtggt
    20461 ggataatctt gtcaatagca atcgtaagag tttagaagtt gttgaaagaa tcacaggagt
    20521 tgagattcct ttctatgagg cagatattcg tgacacagct accctcagag atattttcaa
    20581 gcaggaagaa ccgactggtg tcattcactt tgctggtttg aaggctgttg gcgaatcaac
    20641 acgtatccct cttgcctact atgacaacaa tatcgctgga actgtcagcc ttttgaaagc
    20701 catagaagaa aacaactgta aaaacatcat cttcagttct tctgcgacag tttacgggga
    20761 tccgcacaca gtgcccatct tggaagattt cccactttca gtgaccaacc catacggtcg
    20821 tactaagctc atgctagagg aaattttgac tgatatttac aaagcagact cagaatggaa
    20881 tgttgtcttg cttcgttact ttaacccaat cggagcccat gagagtggtg atttgggaga
    20941 aaatccaaac ggtattccaa acaatctctt gccatatgtg actcaagtag ccgttggaaa
    21001 attagagcaa gtgcaagtgt ttggagacga ttacgatacg gaagatggaa caggtgttcg
    21061 tgactatatc cacgttgtcg atttggctaa gggtcacgtt gcagctttga aaaaaatcca
    21121 aaaaggttca ggactaaacg tttataacct tggaactggt aaaggttact cagttcttga
    21181 aattatccaa aacatggaaa aagcggtggg acgtcctatt ccttaccgta tcgtagaacg
    21241 tcgcccaggt gatatcgctg cctgctactc agacccagca aaagctaaag cagaactcgg
    21301 ttgggaagca gaactcgaca tcacccaaat gtgtgaagac gcatggcgtt ggcaaagcaa
    21361 gcatccaaat ggatttgaag actaagatga tgatttcaat catcgtccct tgtttaaacg
    21421 aagaggaagt acttcctctt ttttatcagg ctctggaagc tttacttcca gatttggaaa
    21481 cagaaatcga gtatgtcttt gtcgatgatg gatcaagtga tgggaccttg gaactcttaa
    21541 aggcctatcg ggagcaaaat ccggcagtcc attatatttc tttctctcga aattttggca
    21601 aagaagcagc cctttatgca ggcttgcaat atgcgacagg agatttggtg gtggtgatgg
    21661 atgcagacct ccaagatcct cctagtatgt tgtttgagat gaaaaatgta ctagacaaaa
    21721 atgtagactt ggactgcgtt gggacacgga gaactagtcg ggagggagaa cccttctttc
    21781 gcagtttctg tgctgttctc ttttatcgcc tcatgcaaaa aatcagccca gtggctctgc
    21841 cgtcgggtgt ccgtgatttt cgtatgatga gaaggtctgt agtcgatgcc attttaagct
    21901 tgaccgagtc caatcgtttt tcaaaggggc tcttcgcctg ggtgggtttc aaaacctact
    21961 atttggacta tccaaatgtc gaaaggcagg ctggcaagac cagttggagt tttaggaaac
    22021 tctttttcta ctccattgaa gggattatta atttttcaga ttttcccttg attatagcct
    22081 ttgtagctgg tctcctatct tgttttcttt ctctgctgat gacctttttt gttgtggttc
    22141 ggaccctcat tttgggcaat ccgacatctg gttggacctc tctgatggct gttattctct
    22201 ttcttggagg cattcaactc ttgaccattg ggattctcgg caagtatatc agtaagattt
    22261 atttagagac taaaaaaaga ccactttatc ttatcaaaga aaaaagtgat gataggctaa
    22321 aaaagataga atttatctga catagtcact ttttgttatt tgtaattctt ttagttcgga
    22381 gtttgggtga tttttaaaag aattagggat ttgaaatgat ttaaaaaatc tatgtagact
    22441 aaatttaaat tgtagtgact taataaataa aaaatttagg agtattatgt tatgctaagt
    22501 aaagaggatt atactgaaga aatcgggcta ataaagaaac aaaattatgt agaggctgaa
    22561 ttgtatccta tagttgctga tataattaag ccaactttaa aagatagttt atcaaaaaga
    22621 tatgtcttcg gaagacaaag aaggggtttg ggacaaattt attatggtct aagtaatttt
    22681 cctgatatag ttattttaga taagacttat gaaaacaaat ctaggaaaag tataaaaatt
    22741 gaagaatgga agaaacttcg aggatgcgtg gaagttaaga atttaaatta tagtttaatt
    22801 acagaggaaa aaatcaaatc aaccatatcg aacagttttg aacatataac tggagagatg
    22861 gaacaactaa ctggagagat gggacaactt attggagacc ttttatggta taaaaaagta
    22921 atttatacaa atggaattga atggagattt ctaagtttag atgacaagga agagatagat
    22981 aatacaattg ttgaagtagt taacaaaaga atagaaacag aagaagcggg aaattctttt
    23041 gattggtgga agaatattaa agatttatcg ttcaattata cggatatatg cctatctaaa
    23101 gattgtagac aagagtggaa tgaatttgta aaaagggtaa aggaaataga atggtagaag
    23161 tctattctca ttgagaaatt tagattttaa gttacagtaa gatttattta gagactaaaa
    23221 aaagaccact ttatcttatc aaagaaaaaa gtgaccttcc tgattttaca gaaaaaaata
    23281 aagtgaaaag actataattt tacatggaaa tgtgctaaac tagagggagt ggattatcgc
    23341 cattgattta ggcttcctgg tttccaatca gggcgcgagt tgggcaattt ttaacagcct
    23401 ctaagacatc ctgactagga gaaatttctt tttccagttg gtcagggtca tcgtaaaaac
    23461 gcacgattcc attatcgtgg taatcaaata aatcagaata agtttggcaa agcccacagg
    23521 cgatacatcg ttcaggtata agtgtgattt tcatgttcat atttatattg taataagaaa
    23581 agtaaaaaaa aacaaggagt aaggtatggc aaaagaaccg tggcaagaag atatctatga
    23641 tcaagaagaa tcaagagcag agcgtcggca tcgaaaccac ggaggggctg ataggatggc
    23701 taatcgtatt ttgacgatcc tagctagtat tttctttgta attgtggtgg tgatggtcat
    23761 cgttctcatc tatctatcat cggggggaag taatcgcaca gcagccttaa aagactttca
    23821 tgattctgat gcaagtgtag tacaaatctc atcttcaagc agttctcagc ctgagcagag
    23881 ttcagagcca gaatctactt ctagtagttc agaagaagct gctaatcctg aaggaacgat
    23941 taaagttctc gcaggagaag gggaagcagc tattgccgct cgtgcaggaa tctccattgc
    24001 tcagttagag gccttgaatc ctgggcacat ggctacagga tcttggtttg ctaatccagg
    24061 tgatgttata aaaataaaat aggagccgat atgaaaacaa ttcaaattgc tattgatggt
    24121 cctgcttcca gcggtaagag tacggtcgca aagattattg ctaaggattt tggattcacc
    24181 taccttgata caggagctat gtatcgtgca gcgacctata tggctcttaa gaaccaatta
    24241 ggagttgaag aagtcgaagc ccttctagcc ttgttggacc agcatccaat cagctttgga
    24301 cgttcagaaa ctggagacca gcttgttttt gtaggagatg tggatattac ccatcctatc
    24361 cgtgaaaatg aagtgaccaa tcatgtttct gctattgcag caattcctga agtgcgtgag
    24421 aaactggttt ctctccaaca agaaattgcc cagcaaggcg ggattgtcat ggatggtcgc
    24481 gatattggaa ctgttgtatt gccacaagca gaattgaaaa ttttcctagt agcttctgtt
    24541 gatgagagag cagagcgtcg ttacaaggaa aatattgcca agggaattga aacagacttt
    24601 gaaaccctaa aaaaggaaat tgctgcgcgt gactacaagg atagtcatcg tgagacttct
    24661 cctctcaaac aagcagagga tgctgtctac cttgatacaa ctggtttgaa cattcaagaa
    24721 gtagttgaaa aaatcaaagc agaagctgaa aaaagaatgt aaatgtagaa aagccgatag
    24781 attgatatcg gtttttttct aaatttgtca aaatgctgat tttagggtat aatagttgct
    24841 gttcgagaaa ttttgatttt caaagaatag tgaatgatga taaggagaaa ccatgaacaa
    24901 tttaccaaat tgtccaaaat gtaactcaga gtatgtctac gaagacggtg ccctactggt
    24961 ttgcccagag tgtgctcatg agtggaatcc tgctgaagtt gcagaagtag aagaaggtct
    25021 tgtcgctatc gatgccaacg gaaataaatt ggctgatggt gatacagtaa ctctcatcaa
    25081 ggacttgaaa gtaaaaggtg cgccaaaaga tttgaaacaa gggacgcgcg tgaaaaatat
    25141 ccgcatcgta gaaggcgacc acaatatcga ctgtaagatt gatggttttg gtgccatgaa
    25201 acttaaatca gagtttgtga ggaagattta agcatgtcaa aacactataa acttgtattt
    25261 tatagccgta tcttcttgtt tctagcggct tttacgggag tttatcttga aattactaag
    25321 catggtggtt ttgggatgct tctctattac acggttctgt ccaacctctt ggtaactatt
    25381 tttacccttt atcttctaaa ggttatgagc cgtgtaggtg aaaattggca aaggccaagt
    25441 ctcttgcgct taaaaggtgg ggtcaccatg agtatcatga ttacctgtgt gatttaccat
    25501 ttcctcttgg cgcccattgc gactaatttc tataccctag aaaatttcct ttgccactat
    25561 atcgttccca tctggttttt agcggatacc ctcttttttg acaaacaggg tcaatacaag
    25621 atttgggatc cagcagtgtg gaccatttta ccctttctgt atatgatgtt tgctcttttt
    25681 aatggcttgg ttctaaaact caatattcca aatgccaagg ataatccttt cccttacttc
    25741 tttttgaatg tgaacaaggg ttggaatgtt gtgtttaagt ggtgtctgat tatctttgtt
    25801 gcctatatgg tagcaggatt tattttctac tttatcaagc aaatcaagag aaagtcatcc
    25861 taatactctt cgaaaatctc ttcaaaccac gtcagtttcc atctgcaacc tcaaaacact
    25921 gttttgaaca acctgcggct agcttcctag tttgctcttt gattttcatt gagtataaga
    25981 tacaagggat tcattttcga atttaagaag gagtctacaa accaatgagg cttcttcttt
    26041 tcttgcttat ttgataacta tcaaaaaagt agaagattaa gagaaatata gaaagagatt
    26101 tcatgaaaca atttttagaa cgggccagca ttttggctct ctccctcgtt ttgattacct
    26161 ccttttccat ttcgagtgcc ctaccagcca tgtttgacta ttatcagggt tattctaagg
    26221 aacaaattga gctcttggtg agcttgcctt cctttggaat catgatgatg ttactgctaa
    26281 atggtttctt agaaaaaata tttcctgagc gcttacagat tagtttgggc ttgctgattt
    26341 tatcattgag cggtacagct cccttctggt accaagccta tccctttgtc tttggaacac
    26401 ggcttctctt tggtttgggt cttgggatga tcaatgccaa ggccatttct attatcagtg
    26461 aacgctacca aggaaaaagg cgaattcaga tgttagggct acgcgcttct gcagaggtcg
    26521 ttggagcttc tctcattacc ttggccgtcg gtcagttgtt ggcctttggt tggacagcta
    26581 tctttctagc ctatagtgct ggatttttgg tgctgcccct ttatctgctc tttgtccctt
    26641 atggaaaatc aaagaaagaa gtcaagaaaa gagcgaagga agcaagtcgt ttaactcgag
    26701 aaatgaaagg cttgattttt accttagcta tcgaagcggc agttgtagtt tgtaccaata
    26761 cagctattac catccgtatt ccaagtttga tggtggaaag aggattgggg gatgcccagt
    26821 tatctagttt tgttcttagt atcatgcagt tgatcgggat tgtggctggg gtgagttttt
    26881 ctttcttgat ttctatcttt aaagagaaac tgctcctctg gtctggtatt acctttggct
    26941 tggggcaaat cgtgattgcc ttgtcttcat ccttgtgggt ggtagtagca ggaagtgttc
    27001 tggctggatt tgcctatagt gtagtcttga cgacggtctt tcaacttgtc tctgaacgaa
    27061 ttccagctaa actcctcaat caagcaactt catttgctgt attaggctgt agtttcggag
    27121 cctttacgac cccatttgtt ctaggtgcaa ttggcttact aactcacaat gggatgttgg
    27181 tctttagtat cttaggaggt tggttgattg taatctctat ctttgtcatg tacctacttc
    27241 agaagagagc ttaggattga ttcctaagtt tttcttttga tactcaatga aaatcaaaga
    27301 gcatagttga ttgagtttgg aatagtacgc tgtagctgct aaaatatttc tagaaattaa
    27361 tttgactttt ctaatagagt tattcatatc ttatttcaat ctactataga aagctagccg
    27421 caggttgctc aaaatagtgt tttgaggttg cagatggaaa ctgacgtggt ttgaagagat
    27481 tttcgaagag tatgagattt ttatacccat acaatatttg ttttaggtcc ttgtttacag
    27541 actaatttct tgataaaata gaggttatga cgagatataa agcaactatt tcctatgatg
    27601 gttatgcctt tgctggcttt cagcgccagc ctcatgcgcg tagcgttcag gaagaaattg
    27661 aaaaaacctt gaccagatta aataaagggc aagccattac tgttcacggt gctggtagga
    27721 cagatagtgg ggttcatgcc ctgggacagg tcattcattt tgacctgcct tatcagatgg
    27781 atgaggagaa actccgtttt gccttggata cccagtctcc tgaagatatt gatgtgattt
    27841 cgattgagct tgtggcagat gattttcatt gccgttatgc caagcatagc aagacctatg
    27901 agtttactgt ggatagagga cgtcccaaaa atccgatgcg ccgtcactat gccacccact
    27961 ttccctaccc actcgatgtg gaacgaatgc agattgcaat caaaaagcta gagggaaccc
    28021 atgattttac cggttttaca gcctctggga ctagtgtaga ggataaggtt cgcaccatca
    28081 cagaagctag tttaatagtc gatgagacag gacaattttt gacctttacc ttttcaggaa
    28141 atggtttctt gtataaacag attcgcaata tggtggggac tcttctcaaa atcggtaaca
    28201 accgcatgcc agtagagcag attgatctca tcttggagaa gaaggacagg caacttgcag
    28261 gtcccactgc agcaccaaat ggtttgtatt taaaggagat tcgttatgaa gaataatcgt
    28321 attttagcac tttctggaaa tgatattttt agtggtggtg gactgtcagc tgatttggct
    28381 acctatacct tgaacggctt gcatgggttt gtagcagtga cttgtttgac agccttgaca
    28441 gaaaaaggat ttgaagtctt tccaactgat gataccattt ttcaacatga attagatagc
    28501 ttgcgtgatg tggaatttgg gggaattaag attggtcttc tccctactgt cagtgtggct
    28561 gagaaggcct tggactttat caaacaacgc ccaggagtac ctgtggtgtt ggatcctgtc
    28621 ttggtctgca aggaaacgca tgatgtagct gtcagtgagc tctgccaaga gttgattcgc
    28681 tttttccctt atgtcagtgt gattacgcct aatctcccag aagcagaatt attatccggt
    28741 caggaaatta aaaccttgga agacatgaaa actgcagcgc agaaattgca tgatttagga
    28801 gcgccagcag tcattatcaa gggaggcaat cgtcttagtc aggacaaggc tgtggatgtc
    28861 ttttatgatg gacagacctt tactatccta gaaaatccag ttatccaagg ccaaaatgct
    28921 ggtgcaggtt gtacctttgc ctctagcatt gccagtcact tgattaaagg tgataaactt
    28981 ttgccagcag tagaaagctc taaggctttc gtttatcgtg ctattgcaca agcagatcag
    29041 tatggagtaa gacaatatga agcaaacaaa aacaactaaa atcgcccttg tatccctatt
    29101 aaccgccctt tctgtggttc taggttattt cttaaaaatc ccaacaccta caggaattct
    29161 aactctttta gatgctggtg tcttctttgc ggccttttac tttggtagtc gtgaaggagc
    29221 ggtagtcgga ggactagcaa gtttcttgat tgacctctta tcaggctacc ctcagtggat
    29281 gttctttagc ttggtcaacc atggcttgca gggatttttc gcaggattta aaggaaaaag
    29341 tcagtggtta ggccttattt tagcaactat tgccatggta ggaggctacg ccttgggttc
    29401 tactttgatg aatggctggg cagcagccct cccagaaatt ctaccaaatt tcatgcaaaa
    29461 tatggtaggg atgattgtag gatttattct tagtcaaagt atcaagaaga ttaagtaata
    29521 ctcttcgaaa atctcttcaa accacgtcag cttccatctg caacctcaaa acactgtttt
    29581 gagcagcctg aggctagctt tctagtttgc actttgattt tcattgagta taaagaggtt
    29641 gagtaaaaag tatttcaaat aagaaaaacg catagtatca ggtgttgaat gaactgcccc
    29701 ccaaaaagtt agacagaaaa aatctaactt tttggggtgt ttttattatg aaattaagtt
    29761 atgatgataa agttcagatc tatgaactta gaaaaca
//
LOCUS       DAVBEO010000025        28765 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 009
            SAMEA1678075-rid20185393.denovo.025, whole genome shotgun sequence.
ACCESSION   DAVBEO010000025 DAVBEO010000000
VERSION     DAVBEO010000025.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678075
            Sequence Read Archive: ERR226392
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 28765)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 28765)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980207.1
            Genome Coverage       :: 150x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:50:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 72 of 147
            Pseudo Genes (incomplete)         :: 72 of 147
            Pseudo Genes (internal stop)      :: 42 of 147
            Pseudo Genes (multiple problems)  :: 32 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..28765
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678075-rid20185393.denovo.025"
                     /strain="KS 009"
                     /db_xref="taxon:1313"
     gene            complement(11..391)
                     /locus_tag="VQ543_001123"
                     /pseudo
     CDS             complement(11..391)
                     /locus_tag="VQ543_001123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            737..1690
                     /locus_tag="VQ543_001124"
     CDS             737..1690
                     /locus_tag="VQ543_001124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000345081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HET2611852.1"
                     /translation="MDFEKIEQAYTYLLENVQVIQSDLATNFYDALVEQNSIYLDGET
                     ELNQVKDNNQALKRLALRKEEWLKTYQFLLMKAGQTEPLQANHQFTPDAIALLLVFIV
                     EELFKEEEITILEMGSGMGILGATFLISLDKKVDYLGMEVDDLLIDLAASMADVIGLQ
                     AGFVQGDAVRPQMLKESDVVISDLPVGYYPDDAVASRHQVASSQEHTYAHHLLMEQGL
                     KYLKSDGYAIFLAPSDLLTSPQSDLLKEWLKEEASLVAMISLPENLFANAKQSKTIFI
                     LQKKSEIAVEPFVYPLASLQDASVLMKFKENFQKWTQGTEI"
     gene            1741..2931
                     /locus_tag="VQ543_001125"
     CDS             1741..2931
                     /locus_tag="VQ543_001125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate kinase"
                     /protein_id="HET2611853.1"
                     /translation="MTKTIAINAGSSSLKWQLYLMPEEKVLAKGLIERIGLKDSISTV
                     KFDGRSEQQILDIENHTQAVKILLDDLIRFDIIKAYDEITGVGHRVVAGGEYFKESTV
                     VEGDVLEKVEELSLLAPLHNPANAAGVRAFKELLPDITSVVVFDTSFHTSMPEKAYRY
                     PLPTKYYTENKVRKYGAHGTSHQFVAGEAAKLLGRPLEDLKLITCHIGNGGSITAVKA
                     GKSVDTSMGFTPLGGIMMGTRTGDIDPAIIPYLMQYTEDFNTPEDISRVLNRESGLLG
                     VSANSSDMRDIEAAVAEGNHEASLAYEMYVDRIQKHIGQYLAVLNGTDAIVFTAGVGE
                     NAENFRRDVISGISWFGCDVDDEKNVFGVTGDISTEAAKIRVLVIPTDEELVIARDVE
                     RLKK"
     gene            3080..3451
                     /gene="rnpA"
                     /locus_tag="VQ543_001126"
     CDS             3080..3451
                     /gene="rnpA"
                     /locus_tag="VQ543_001126"
                     /EC_number="3.1.26.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000739244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component"
                     /protein_id="HET2611854.1"
                     /translation="MKKNFRVKREKDFKAIFKEGTSFANRKFVVYQLENQKNHFRVGL
                     SVSKKLGNAVTRNQIKRRIRHIIQNAKGSLVEDVDFVVIARKGVETLGYAEMEKNLLH
                     VLKLSKIYREGNGSEKETKVD"
     gene            3426..4250
                     /locus_tag="VQ543_001127"
     CDS             3426..4250
                     /locus_tag="VQ543_001127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000727905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HET2611855.1"
                     /translation="MKKKLKLTSLLGLSLLIMTACATNGVTSDITAESADFWSKLVYF
                     FAKIIRFLSFDISIGVGIILFTVLIRTVLLPVFQVQMVASRKMQEAQPRIKALREQYP
                     GRDMESRTKLEQEMRKVFKEMGVRQSDSLWPILIQMPVILALFQALSRVDFLKTGHFL
                     WINLGSVDTTLVLPILAAVFTFLSTWLSNKALSERNGATTAMMYGIPVLIFIFAVYAP
                     GGVALYWTVSNAYQVLQTYFLNNPFKIIAEREAVVQAQKDLENRKRKAKKKAQKTK"
     gene            4269..5255
                     /locus_tag="VQ543_001128"
     CDS             4269..5255
                     /locus_tag="VQ543_001128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein jag"
                     /protein_id="HET2611856.1"
                     /translation="MVVFTGSTVEEAIQKGLKELDIPRMKAHIKVISREKKGFLGLFG
                     KKPAQVDIEAISETTVVKANQQVVKGVPKKINDLNEPVKTVSEETVDLGHVVDAIKKI
                     EEEGQGISDEVKAEILKHERHASTILEETGHIEILNELQIEEAMREEAGADDLETEQD
                     QTENQDLKEMGLKVEQSYDIAQVATDVTAYVQAIVDDMDVEATLSNDYNRRSINLQID
                     TNEPGRIIGYHGKVLKALQLLAQNYLYNRYSKTFYVTINVNDYVEHRAEVLQTYAQKL
                     AIRVLEEGRSHQTDPMSNSERKIIHRIISRMDGVTSYSEGDEPNRYVVVDTE"
     gene            5306..5929
                     /locus_tag="VQ543_001129"
     CDS             5306..5929
                     /locus_tag="VQ543_001129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000932659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P"
                     /protein_id="HET2611857.1"
                     /translation="MLNKIRDYLDFAGLQYRNPDKAGAEREKMLAFRHKGQEARKAFT
                     ELAKAFQASHPGWQLQQTSQWMNQAQRLRPHFWVYLQRDEQVTEPMMALRLYGTSTDF
                     GISLEVSFIERKKDEQTLGKQAKVLDIPTVKGIYYLTYSNGQSQRWEANEEKRRTLRE
                     KVRSQEVRKVLVKVDVPMTENSSEEEIVEGLLKSYSKILPYYLATRK"
     gene            6060..7517
                     /locus_tag="VQ543_001130"
     CDS             6060..7517
                     /locus_tag="VQ543_001130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HET2611858.1"
                     /translation="MEVVSSVLNWFSSNILQNPAFFVGLLVLIGYALLKKPAHDVFSG
                     FVKATVGYMLLNVGAGGLVTTFRPILAALNYKFQIGAAVIDPYFGLAAANNKIAAEFP
                     DFVGTATTALLIGFGINILLVALRKITKVRTLFITGHIMVQQAATVSLMVLFLVPQLR
                     NAYGTAAIGIICGLYWAVSSNMTVEATQRLTGGGGFAIGHQQQFAIWFVDKVAGRFGK
                     KEESLDNLKLPKFLSIFHDTVVASATLMLVFFGAILLILGPDIMSNKEVITSGTLFNP
                     AKQDFFMYIIQTAFTFSVYLFVLMQGVRMFVSELTNAFQGISNKLLPGSFPAVDVAAS
                     YGFGSPNAVLSGFTFGLIGQLITIVLLIVFKNPILIITGFVPVFFDNAAIAVYADKRG
                     GWKAAVILSFISGVLQVALGALCVALLDLASYGGYHGNIDFEFPWLGFGYIFKYLGIV
                     GYVLVCLFLLVIPQLQFAKAKDKEKYYNGEVQEEA"
     gene            7540..7821
                     /locus_tag="VQ543_001131"
     CDS             7540..7821
                     /locus_tag="VQ543_001131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HET2611859.1"
                     /translation="MVKVLAACGNGMGSSMVIKMKVENALRKLNQTDFTVNSCSVGEA
                     KGLAVGYDIVIASLHLIQELEGRTNGKLIGLDNLMDDKEITEKLSQALQ"
     gene            7898..8383
                     /locus_tag="VQ543_001132"
     CDS             7898..8383
                     /locus_tag="VQ543_001132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HET2611860.1"
                     /translation="MNLKQALIDNDSIRLGLEANNWKEAVKVAVDPLIESGAILPEYY
                     DAIIESTEEYGPYYILMPGMAMPHARPEAGVQSDAFSLITLQNPVVFSDGKEVSVLLA
                     LAATSSKIHTSVAIPQIIALFELEDSIARLQACQTKEDVLAMIEESKDSPYLEGLDLE
                     S"
     gene            8400..9065
                     /locus_tag="VQ543_001133"
     CDS             8400..9065
                     /locus_tag="VQ543_001133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-keto-L-gulonate-6-phosphate decarboxylase
                     UlaD"
                     /protein_id="HET2611861.1"
                     /translation="MTKRIPNLQVALDHSDLQGAIKAAVSVGQEVDIIEAGTVCLLQV
                     GSELAEVLRSLFPDKIIVADTKCADAGGTVAKNNAVRGADWMTCICCATIPTMEAALK
                     AIKTERGERGEIQIELYGDWTFEQAQLWLDAGISQAIYHQSRDALLAGETWGEKDLNK
                     VKKLIDMGFRVSVTGGLDVDTLKLFEGVDVFTFIAGRGITEAADPAGAARAFKDEIKR
                     IWG"
     gene            9069..9932
                     /locus_tag="VQ543_001134"
     CDS             9069..9932
                     /locus_tag="VQ543_001134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000252119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 3-epimerase"
                     /protein_id="HET2611862.1"
                     /translation="MVRPIGIYEKATPTHFTWLERLNFAKELGFDFVEMSIDERDERL
                     ARLDWSKEERLEVVKEIYETGVRIPSICFSGHRRYPLGSKDPVLEEKSLELMKKCIEL
                     AQDLGVRTIQLAGYDVYYEEKSPQTRQRFIKNLRKACDWAEEAQVVLAIEIMDDPFIN
                     SIEKYLAIEKEIDSPFLFVYPDIGNVSAWHNDIYSEFYLGHHAIAALHLKDTYAVTES
                     SRGQFRDVPFGQGCVKWEEAFDILKETNYNGPFLIEMWSENCETVEETRAAIQEAQAF
                     LYPLIKKAGLM"
     gene            9934..10638
                     /locus_tag="VQ543_001135"
     CDS             9934..10638
                     /locus_tag="VQ543_001135"
                     /EC_number="5.1.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001077552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HET2611863.1"
                     /translation="MNQVINAMRKRVCDANQSLPKHGLVKFTWGNVSEVNRELGVIVI
                     KPSGVDYDELTPENMVVTDLDGKILEGDLRPSSDLPTHVQLYKAWSEIGSVVHTHSTE
                     AVAWAQAGRDIPFYGTTHADYFYGSIPCARSLTKDEVEVAYEKDTGLVIVEEFEHRGL
                     NPVEVPGIVVRNHGPFTWGKNPENAVYHSVVLEEVSKMNRFTEQINPRVGPAPQYILE
                     KHYQRKHGPNAYYGQK"
     gene            10817..12490
                     /locus_tag="VQ543_001136"
     CDS             10817..12490
                     /locus_tag="VQ543_001136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HET2611864.1"
                     /translation="MVLDKASCDLLQYLMDQETSKTIMAISKDLKESRRKIYYHIDKI
                     NAALGDEALHIISIPRIGIHLTEEQRDACCKLLSEVDSYDYIMSAHERMMIMLLWIGI
                     SKERITIEKLIELTEVSRNTVLNDLNSIRYQLTLEQYQVILQVSKSQGYHLHAHPLNK
                     IQYLQSLLYHIFMEENATFVSILEDKMKERLDDECLLSVEMNQFFKEQVPLVEQDLGK
                     KINHHEITFMLQVLPYLLLSCHNVEQYQERHQDIEKEFSLIRKRIEYQVSKKLGERLF
                     QKFEISLSGLEVSLVAVLLLSYRKDLDIHAESDDFRQLKLALEEFIWYFESQIRMEIE
                     NKDDLLRNLMIHCKALLFRKTYGIFSKNPLTKQIRSKYGELFLVTRKSAEILEGAWFI
                     RLTDDDIAYLTIHIGGFLKYTPSSQKNMKKVYLVCDEGVAVSRLLLKQCKLYFPNEQI
                     DTVFTTEQFKSVEDIAQVDVVITTNDDLDSRFPILRVNPILEAEDILKMLDYLKHNIF
                     RNKSKSFSENLSSLISSYIVDSKLASKFQEEVQTLINQEIVVQAFLEDI"
     gene            12602..13693
                     /gene="ulaG"
                     /locus_tag="VQ543_001137"
     CDS             12602..13693
                     /gene="ulaG"
                     /locus_tag="VQ543_001137"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ascorbate 6-phosphate lactonase"
                     /protein_id="HET2611865.1"
                     /translation="MPNVKEITRESWILATFPEWGTWLNEEIEEEVVPEGNFAMWWLG
                     NCGTWIKTPAGANVVMDLWSNRGKSTKKVKDMVRGHQMANMAGVRKLQPNLRVQPMVI
                     DPFAINELDYYLVSHFHSDHIDPYTAAAILNNPKLEHVKFIGPYHCGRIWEGWGVPKE
                     RIIVVKPGDTIELKDMKIHAVESFDRTCLVTLPVNGADETGGELAGLAVTDEEMAQKA
                     VNYIFETPGGTIYHGADSHFSNYFAKHGKDFKIDVALNNYGENPVGIQDKMTSIDLLR
                     MAENLRTKVIIPVHYDIWSNFMASTNEILELWKMRKDRLQYDFHPFIWEVGGKYTYPQ
                     DQHLVEYHHPRGFDDCFEQDSNIQFKALL"
     gene            13807..15783
                     /gene="tkt"
                     /locus_tag="VQ543_001138"
     CDS             13807..15783
                     /gene="tkt"
                     /locus_tag="VQ543_001138"
                     /EC_number="2.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004185329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HET2611866.1"
                     /translation="MSNLSVNAIRFLGIDAINKANSGHPGVVMGAAPMAYSLFTKQLH
                     INPAQPNWINRDRFILSAGHGSMLLYALLHLSGFEDVSMDEIKSFRQWGSKTPGHPEF
                     GHTAGIDATTGPLGQGISTATGFAQAERFLAAKYNREGYNIFDHYTYVICGDGDLMEG
                     VSSEAASYAGLQKLDKLVVLYDSNDINLDGETKDSFTESVRDRYNAYGWHTALVENGT
                     DLEAIHAAIETAKASGKPSLIEVKTVIGYGSPNKQGTNAVHGAPLGADETASTRQALG
                     WDYEPFEIPEQVYADFKEHVADRGASAYQAWTKLVTDYKEAHPELAAEVEAIIDGRDP
                     VEVTPADFPALENGFSQATRNSSQDALNVVAAKLPTFLGGSADLAHSNMTYIKTDGLQ
                     DDANRLNRNIQFGVREFAMGTILNGMALHGGLRVYGGTFFVFSDYVKAAVRLSALQGL
                     PVTYVFTHDSIAVGEDGPTHEPVEHLAGLRAMPNLNVFRPADARETQAAWYLAVTSEK
                     TPTALVLTRQNLTVEDGTDFDKVAKGAYVVYENAADFDTILIATGSEVNLAVSAAKEL
                     ASQGEKIRVVSMPSTDVFDKQDAAYKEEILPNAVRRRVAVEMGASQNWYKYVGLDGAV
                     LGIDTFGASAPAPKVLAEYGFTVENLVKVVRNLK"
     gene            15900..16199
                     /gene="yajC"
                     /locus_tag="VQ543_001139"
     CDS             15900..16199
                     /gene="yajC"
                     /locus_tag="VQ543_001139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001069053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HET2611867.1"
                     /translation="MNPNITFLIMLVGMMALMFFMQRSQKKQAQKRMESLNKLQKGYE
                     VITIGGLYGTVDEVDTEKGTIVLDVEGVYLTFELAAIKTVLPLKETASLEGAIEK"
     gene            16246..16674
                     /locus_tag="VQ543_001140"
     CDS             16246..16674
                     /locus_tag="VQ543_001140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000737444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="low molecular weight phosphotyrosine protein
                     phosphatase"
                     /protein_id="HET2611868.1"
                     /translation="MKKLVFVCLGNICRSPMAEFVMKSMTDNYEIQSRATSSWEHGNP
                     IHKGTQGIFQEYEIPYDKNKTSLQISKEDFEAFDYIIGMDASNISDLRQMCPVDCQDK
                     IYSFSSESVPDPWYTGDFEETYRRVQEGCQAWLERLEKES"
     gene            16676..17086
                     /locus_tag="VQ543_001141"
     CDS             16676..17086
                     /locus_tag="VQ543_001141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000427064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2611869.1"
                     /translation="MENLTNFYEKYRVYLTRPRLELLAVVTIVFCAVLVFFLNIPGKG
                     VLKLDNGTIVYDGSLVRGKMNGQGTITFQNGDQYTGGFNNGAFNGKGTFQSKEGWTYE
                     GDFVNGQAEGKGKLTTEQEVVYEGTFKQGVFQQK"
     gene            17386..20037
                     /gene="adhE"
                     /locus_tag="VQ543_001142"
                     /gene_synonym="adhC"
     CDS             17386..20037
                     /gene="adhE"
                     /locus_tag="VQ543_001142"
                     /gene_synonym="adhC"
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000763984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="HET2611870.1"
                     /translation="MADKKTVTPEEKKLVAEKHVDELVQKALVALEEMRKLDQEQVDY
                     IVAKASVAALDAHGELALHAFEETGRGVFEDKATKNLFACEHVVNNMRHTKTVGVIEE
                     DDVTGLTLIAEPVGVVCGITPTTNPTSTAIFKSLISLKTRNPIVFAFHPSAQESSAHA
                     ARIVRDAAIAAGAPENCVQWITEPSMEATSALMNHEGIATILATGGNAMVKAAYSCGK
                     PALGVGAGNVPAYVEKSANIRQAAHDIVMSKSFDNGMVCASEQAVIIDKEIYDEFVAE
                     FKSYHTYFVNKKEKALLEEFCFGVKANSKNCAGAKLNADIVGKPATWIAEQAGFTVPE
                     GTNILAAECKEVGENEPLTREKLSPVIAVLKSESREDGITKARQMVEFNGLGHSAAIH
                     TADEELTKEFGKAVKAIRVICNSPSTFGGIGDVYNAFLPSLTLGCGSYGRNSVGDNVS
                     AINLLNIKKVGRRRNNMQWMKLPSKTYFERDSIQYLQKCRDVERVMIVTDHAMVELGF
                     LDRIIEQLDLRRNKVVYQIFADVEPDPDITTVNRGTEIMRAFKPDTIIALGGGSPMDA
                     AKVMWLFYEQPEVDFRDLVQKFMDIRKRAFKFPLLGKKTKFIAIPTTSGTGSEVTPFA
                     VISDKANNRKYPIADYSLTPTVAIVDPALVLTVPGFVAADTGMDVLTHATEAYVSQMA
                     SDYTDGLALQAIKLVFENLESSVKNADFHSREKMHNASTIAGMAFANAFLGISHSMAH
                     KIGAQFHTIHGRTNAILLPYVIRYNGTRPAKTATWPKYNYYRADEKYQDIARMLGLPA
                     STPEEGVESYAKAVYELGERIGIQMNFRDQGIDEKEWKEHSRELAFLAYEDQCSPANP
                     RLPMVDHMQEIIEDAYYGYKERPGRRK"
     gene            complement(21022..21330)
                     /locus_tag="VQ543_001143"
     CDS             complement(21022..21330)
                     /locus_tag="VQ543_001143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000134125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HET2611871.1"
                     /translation="MTEEMEYICFQLIANSGAAKSSFIEAIQLAKAGNLKEAKIKVEE
                     AEDSLVEAHKIHSNLIQKEATGEKIGFSLLFMHAEDQMASTEIIQLLSKEFIDLYQNK
                     "
     gene            complement(21327..21635)
                     /locus_tag="VQ543_001144"
     CDS             complement(21327..21635)
                     /locus_tag="VQ543_001144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HET2611872.1"
                     /translation="MKQILLVCNAGMSTSMLVKKMQQSATERGIEISIQAKSMTEAKK
                     NIHEADVILIGPQIRYELLAVKEIAGNIPVDTIDMRDYGMMNGAKVLEQALAWIGEIR
                     "
     gene            complement(21640..22935)
                     /locus_tag="VQ543_001145"
     CDS             complement(21640..22935)
                     /locus_tag="VQ543_001145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000798148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HET2611873.1"
                     /translation="MKNSKFIDQFATFAGKLGNQIHLKTLRDAFVTVMPLYILAGLIV
                     LLNNTVFKWIFQGDTLTKFQYWGITIANGTLSISGMIIAVMVGYFLAKNRDFENPSAA
                     SMLSLVSLIVMMPNTVSVVPDGAKDAVNISGVLSFNNTGTGAMFAGVIVAIIATELFI
                     ELSNVKALQMNLGENIPPAVSRSFSVLLPVMTVISLFGIVSALLFNITGMNLISIITI
                     FIQEPIRHIGTSLIGVIIIYSLGNMLWLFGIHQAVIYSAILEPLLLINITENITAANN
                     GQAIPHIINLSQIQTFALMGGSGSTLCLLIATFLVSRNAVSKNVAKLSFGPGIFNINE
                     PVLFGYPIVYNISLAIPFITVPVLGILISYLATVTGFMSPAFIQVPWTTPVFLNAWLA
                     TAGDVRAVLVQFIIFALGVLLYIPFIKVNDKVVEQEMEG"
     gene            complement(22953..24362)
                     /locus_tag="VQ543_001146"
     CDS             complement(22953..24362)
                     /locus_tag="VQ543_001146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HET2611874.1"
                     /translation="MKKKLVFPNLFWWGAASSGPQTEGQYGKVHENVMDYWFKTHPED
                     FFDNVGPLVASNFFHTYTEDFHLMKEIGVNSFRTSIQWSRLIKNLETGEPDPKGIAFY
                     NAIIEEAKKNQMDLVMNLHHFDLPVELLQKYGGWESKHVVELFVKFAKTAFTCFGDKV
                     HYWTTFNEPMVIPEAGYLYAFHYPNLKGKGKEAVQVIYNLNLASAKVIQLYRSLGLDG
                     KIGIILNLTPAYPRSNSPEDLEASRFTEDFFNKVFLNPAVKGTFPERLVKQLERDGVL
                     WSHTEKELQLMKSNTVDFLGVNYYHPKRVQAQANPEEYQTPWMPDQYFKEYEWPERRM
                     NPYRGWEIFPKAIYDIAMIVKEEYGNIPWFISENGMGVENEARFIDENGVIDDVYRIE
                     FYEEHLRWLHKAIEEGSLCFGYHAWTAFDCWSWNNAYKNRYGFISVDLETQKRTIKSS
                     GRWYRKVSDNNGFEVEIEE"
     gene            24520..25248
                     /locus_tag="VQ543_001147"
     CDS             24520..25248
                     /locus_tag="VQ543_001147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HET2611875.1"
                     /translation="MSTKYLFIYNEIREKILCNKYTMNEQLPDEMTLAKQFACSRMTI
                     KKALDLLVSEGLIFRKRGQGTFVLSRGSSKRKLIVPERDIRGLTKISEDAHSTIDSRI
                     IHFKLEFANEFLAEKLQVALQSPVYNIYRLRIIDGKPYVLEQTYMSTDVIPGITEDIL
                     QKSIYNYIEGKLGLHIASATKILRASSSSENEQHYLQLLPTEPVFEVEQVAYLDNGTP
                     FEYSISRHRYDLFEFNSFALRHSS"
     gene            25708..25902
                     /locus_tag="VQ543_001148"
     CDS             25708..25902
                     /locus_tag="VQ543_001148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HET2611876.1"
                     /translation="MKGKEYENRTVSFAISSKGEKMKVENISYRVDHRILFDNISFDT
                     SSSDVTLITGKNGTGKSTLL"
     gene            complement(26268..27578)
                     /locus_tag="VQ543_001149"
     CDS             complement(26268..27578)
                     /locus_tag="VQ543_001149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000581523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SLC13 family permease"
                     /protein_id="HET2611877.1"
                     /translation="MIHLIMISAIALAIGIGYRTKINIGLLAIAFSYLIATTLMGLSP
                     KELLHFWPTSLFFTIFSVSLFYNFAITNGTLDVLAQHILYRTRTYPNALYMILYLMAT
                     LLSALGAGFFTTMAVCCPLAITLCQKADKHPLIGAQAVNWGASGGANLITSSSGIVFQ
                     GLFKQMGWEEQAFSLGNHIFIVSIIYPLIVLLLLSCYSHYSKGRTNSSLTIDQPPLLS
                     KVQRQTTLLMISSMVLVWLFPLLHLIFPNIAWIATYRKTFDIGFVSILMVCLALRLKL
                     GKQEAILAKVPWATIIMLCGMSLLMSLAVKSGLVTLIGHLMTTSIPHFWLPLFFCVIA
                     GVMSLFSSTLSVVAPALFPIIAIISAQNPQIDIHLLTTATVIGALSTNISPFSSAGSL
                     IQLSLPNIEERGLAFKKQIILGVPISLSLGLLTTWILILLASLS"
     gene            27815..28687
                     /locus_tag="VQ543_001150"
     CDS             27815..28687
                     /locus_tag="VQ543_001150"
                     /EC_number="2.4.2.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxylating nicotinate-nucleotide
                     diphosphorylase"
                     /protein_id="HET2611878.1"
                     /translation="MSIISTDLTPFQIDDTLKAALREDVHSEDYSTNAIFDHHGQAKV
                     SLFAKEAGVLAGLTVFQRVFTLFDAEVTFQNPHQFKDGDRLTSGDLVLEIIGSVRSLL
                     TCERVALNFLQHLSGIASMTAAYVEALGDDCIKVFDTRKTTPNLRLFEKYAVRVGGGY
                     NHRFNLSDAILLKDNHIAAVGSVQKAIAQARAYAPFVKMVEVEVESLAAAEEAAAAGA
                     DIIMLDNMSLEQIEQAITLIAGRSRIECSGNIDMTTISRFRGLAIDYVSSGSLTHSAK
                     SLDFSMKGLTYLDV"
BASE COUNT         9000 a         5131 c         5988 g         8646 t
ORIGIN      
        1 agaatcattc gctaattctt tttttagggc gattgatttg tacttccgtc gcatcaatca
       61 ttaccgtgtc ctcagaactg agaggagttc ttgaaatcgt aacaccactt tgaacaagag
      121 ttacttcaac ccattggctc cgacggatta agttgctttc gtggatacca aaatcagccg
      181 caatttcttc ataagtgcgg tattctcgca catattgaag agtgcccata agaaggtctt
      241 ctaggcttaa tttaggtttt cgtccacctt ttgcgtgttt aagttgataa gctgttttta
      301 atacagctaa catctcttta aaagtcgtgc gctgaacacc aacaagacgc ttaaattgtg
      361 cattggttag ttgtttactt tcttcataaa ttttattgta tcatattttt gtttcacagg
      421 aagtctaata aataaaaatt ctttaaaatt ttgttgggaa aatgggaaaa gatataaatg
      481 gaaacttagt ataacacttg gaaaactctg taaaaatagt aagtcaattc atgtcccgtt
      541 ttttctctag ggaagttggg cggctatatt tatatgacca tttgtcgtaa taaacatccc
      601 taccaagggt caatagaaat aaattcaacg aaacttttgc tgtcagattt agatgcccaa
      661 tttgtcattt atactctttc atataggact ttctataagg atggaaaaaa gaagggaaat
      721 ttgataagat aggaatatgg attttgaaaa aattgaacaa gcttatacct atttactaga
      781 gaatgtccaa gtcatccaaa gtgatttggc gaccaacttt tatgacgcct tggtggagca
      841 aaacagcatc tatctggatg gtgaaactga gctaaaccag gtcaaagaca acaatcaggc
      901 ccttaagcgt ttagcactac gcaaagaaga atggctcaag acctaccagt ttctcttgat
      961 gaaggctggg caaacagaac ccttgcaggc caatcaccag tttacaccgg atgctattgc
     1021 tttgcttttg gtgtttattg tggaagagtt gtttaaagag gaggaaatta ctatcctcga
     1081 aatgggttct gggatgggaa ttctaggcgc tactttcttg atctcgcttg ataaaaaggt
     1141 ggattacttg ggaatggaag tggatgattt gctgattgat ctggcagcta gcatggcaga
     1201 tgtaattggt ttgcaggctg gctttgtcca aggagatgcc gttcgtccac aaatgctcaa
     1261 agaaagcgat gtggtcatca gtgacttgcc tgttggctat tatcctgatg atgccgttgc
     1321 gtcgcgccat caagttgctt ctagccaaga acatacttac gcccatcact tgctcatgga
     1381 acaagggctt aagtacctca agtcagacgg atacgctatt tttctagctc cgagtgattt
     1441 gttgaccagt cctcaaagtg atttgttaaa agaatggctg aaagaagagg cgagtctggt
     1501 tgctatgatt agtctgcctg aaaatctctt tgctaatgct aaacaatcta agactatttt
     1561 tatcctacag aagaaaagtg aaatagcagt ggagcctttt gtttatccac ttgctagctt
     1621 gcaagatgca agtgttttaa tgaaatttaa agaaaatttt caaaaatgga ctcaaggtac
     1681 tgaaatataa aatagatttt gttataatag ttgaaaacgc ttaaaaaggg gtatcatgtt
     1741 atgacaaaaa caattgcaat caatgcagga agttcaagtt tgaaatggca attatactta
     1801 atgccagagg aaaaagtgtt agccaaaggt ttgattgaac gtatcggttt gaaagattca
     1861 atttcaactg taaaatttga cggccgttct gaacaacaaa ttttggatat cgaaaatcat
     1921 acacaagctg ttaaaatttt attggatgac ttgattcgtt tcgatattat caaggcttat
     1981 gacgagatta caggtgttgg ccaccgtgtt gtagcaggtg gagaatattt caaagaatca
     2041 acagttgttg agggagatgt tttagaaaaa gttgaagagt tgagtttgtt ggctcctcta
     2101 cacaacccgg ccaatgcagc aggtgttcgt gctttcaagg aattgttgcc agacattacc
     2161 agtgtagttg tttttgatac ttccttccac acaagtatgc cagagaaagc ttatcgctac
     2221 cctctaccaa caaaatatta cacagaaaac aaggttcgta aatacggtgc tcatggtaca
     2281 agtcaccagt ttgtagcagg agaagctgca aaactcttgg gacgtccatt agaagacttg
     2341 aagttaatta cctgtcatat tggtaacgga ggctcaatta cagctgtgaa agccggcaaa
     2401 tctgtagaca cttctatggg gttcactcct cttggtggta ttatgatggg aacgcgtaca
     2461 ggggatattg atccagctat cattccttat ttaatgcaat atacagagga ttttaacaca
     2521 ccagaagata tcagtcgtgt tcttaaccgt gaatcaggtc ttttgggagt ttctgctaat
     2581 tctagcgata tgcgcgatat agaagcagct gtagcagaag ggaatcacga ggctagcttg
     2641 gcttatgaaa tgtatgttga ccgtatccaa aaacatatcg gtcagtacct tgcagtgcta
     2701 aatggaacag atgccattgt tttcacagca ggtgtcggtg aaaatgcaga gaatttccgt
     2761 cgtgatgtaa tctcagggat ttcgtggttt ggttgtgatg ttgatgatga aaagaatgtc
     2821 tttggcgtta caggagacat ctcaacagag gcagctaaaa tccgtgtctt ggttattcca
     2881 acagatgaag aattagtcat tgcccgtgac gttgaacgct tgaaaaaata agtgaaacta
     2941 aaaaaatatt caatacaagg agttgggaaa gttatttttc cagcttcttt ttctgatgaa
     3001 attgtccaaa accttgctat gattggcttt tttgaaaaat atggtataat agtagtaatt
     3061 taatagatgg agttgagttt tgaagaaaaa ctttcgtgta aaaagagaga aagattttaa
     3121 ggcgattttc aaggagggga caagttttgc taatcgcaaa tttgtggtct accaattaga
     3181 aaaccagaaa aaccattttc gagtaggtct atcagttagc aaaaaactgg ggaatgccgt
     3241 cactagaaat caaattaagc gacggattcg gcatattatc cagaatgcaa aagggagtct
     3301 ggtagaagat gtcgactttg ttgtcattgc tcgaaaagga gtcgaaacct tgggatacgc
     3361 agagatggag aaaaatctac tccatgtatt aaaattatca aagatttacc gggaaggaaa
     3421 tgggagtgaa aaagaaacta aagttgacta gtttgctagg actgtctctg ttaatcatga
     3481 cagcctgtgc gactaatggg gtaactagcg atattacagc cgaatcggct gatttttgga
     3541 gtaaattggt ttacttcttt gcgaaaatca ttcgcttttt atcgtttgat attagtatcg
     3601 gagtggggat tattctcttt acggtcttga ttcgtacagt cctcttgcca gtctttcagg
     3661 tgcaaatggt ggcttctagg aaaatgcagg aagctcagcc acgcattaag gcgcttcgag
     3721 aacaatatcc aggtcgagat atggaaagca gaaccaaact agagcaggaa atgcgtaaag
     3781 tatttaaaga aatgggtgtc agacagtcag attctctttg gccgattttg attcagatgc
     3841 cggttatttt ggccttgttc caagccctat caagagttga ctttttaaag acaggtcatt
     3901 tcttatggat taaccttggt agtgtggata caacccttgt tcttccgatt ttagcagcag
     3961 tattcacctt tttaagtact tggttgtcca acaaagcttt gtctgagcga aatggcgcta
     4021 cgactgcgat gatgtatggg attccagtct tgatttttat ctttgcagtt tatgcgccag
     4081 gtggagtcgc cctatactgg acagtgtcta atgcttatca agtcttgcaa acctatttct
     4141 tgaataatcc attcaagatt atcgcagagc gcgaggccgt agtacaggca caaaaagatt
     4201 tggaaaatag aaaaagaaaa gccaagaaaa aggctcagaa aacgaaataa ataaggagga
     4261 atctggtaat ggtagtattt acaggttcaa ctgttgaaga agcaatccag aaaggattga
     4321 aagaattaga tattccaaga atgaaggctc atatcaaagt catttctagg gagaaaaaag
     4381 gctttcttgg tctatttggt aaaaaaccag cccaagtgga tattgaagcg attagtgaaa
     4441 cgactgttgt caaagcaaat caacaggtag taaaaggcgt tccgaaaaaa atcaatgatt
     4501 tgaacgagcc tgtgaagacg gttagtgaag aaaccgttga ccttggtcat gtggttgatg
     4561 ctattaaaaa aatagaggaa gaaggtcaag gtatttctga tgaagtcaag gctgaaatct
     4621 taaaacatga aagacatgcc agcactatct tagaagaaac tggtcacatt gagattttaa
     4681 atgaacttca aatcgaggaa gcgatgaggg aagaagcagg cgctgatgac cttgaaactg
     4741 agcaagatca aactgaaaat caagacttga aagagatggg cttgaaggtc gagcaaagtt
     4801 atgatattgc ccaggtggct acggatgtga ctgcctatgt tcaagcgatt gtggatgaca
     4861 tggatgttga agctacactt tcaaatgatt ataaccgtcg tagcatcaat ctacaaattg
     4921 acaccaacga accaggtcgt attatcggct accatggtaa agtcttgaag gccttgcaac
     4981 tgttggctca aaattatctt tacaaccgct attccaaaac cttctacgtt acaatcaatg
     5041 tcaatgatta tgtcgaacac cgtgcagaag tcttgcagac ctatgcgcaa aaattggcga
     5101 ttcgtgtttt agaagaagga cgtagtcatc aaacagatcc aatgtcgaat agtgaacgca
     5161 agattatcca ccgtattatt tcacgtatgg atggcgtgac cagttactct gaaggtgatg
     5221 agccaaatcg ctatgtcgtt gtagatacag aataagtaaa atcagggttg acctgatttt
     5281 ttgctagcta gaggaggtta aactaatgtt gaataagata agagactatt tagactttgc
     5341 tggtttgcag taccgtaatc ctgataaagc gggagcagag cgagagaaga tgctggcatt
     5401 ccgccacaaa ggacaagagg cccgaaaggc ttttacagaa ctggccaaag cctttcaagc
     5461 aagccatcca ggatggcaac tccaacagac tagtcagtgg atgaatcagg cccagcgttt
     5521 gagaccacat ttttgggttt atctacagag agacgaacaa gtgacagaac ctatgatggc
     5581 cttacgtttg tatgggacat ctactgactt tggaatttct ttggaagtca gtttcatcga
     5641 acgtaagaag gatgagcaaa cactgggcaa gcaggccaaa gttttagaca ttccaaccgt
     5701 taaagggatt tattatctaa cctactctaa tggtcaaagt caacggtggg aggcgaatga
     5761 agaaaagcgt cgtactttac gcgagaaggt gagaagtcaa gaagttcgaa aagttttagt
     5821 gaaggtagat gttcctatga cagaaaattc gtctgaagaa gaaatcgtag aaggcttatt
     5881 gaagtcttat tctaaaattc ttccctatta tctagctacg agaaaataag ataatttgta
     5941 aaacatcata aatcatacag tccaagagtg aacagtccgc tgtgtaattc ttggtctttt
     6001 tgtttgcgct ttcgcattat ataataaact tacaaaaaca attcaaaagg agaacaatta
     6061 tggaagtcgt ttcaagtgtt ctaaattggt tttctagcaa tattttgcag aatcccgcat
     6121 ttttcgtagg tttattggtg ttgataggat atgcactttt gaaaaaacct gcccatgacg
     6181 ttttttcagg gtttgttaaa gcaacagtag ggtatatgtt gcttaacgtg ggtgctggtg
     6241 gtttggttac aacctttcgt ccaatcttag cagctcttaa ctacaaattc caaattggtg
     6301 cagcggttat cgacccttac tttggacttg ctgcagcaaa caacaaaatt gcagcagagt
     6361 ttccagattt tgttggaact gcaactacag ctctattgat tggttttgga ataaatatct
     6421 tgctcgtagc tcttcgaaag attacgaagg taagaaccct ctttattact ggtcacatca
     6481 tggtacaaca agctgcaaca gtatctctta tggttctatt cttagtacca caattgcgca
     6541 atgcttacgg tacagcagcg attggtatca tctgtggact ttactgggca gttagttcaa
     6601 atatgactgt tgaggcaact caacgcttga ctggtggtgg cggatttgcg attggtcacc
     6661 aacagcaatt tgcaatctgg tttgtagata aagtagcagg acgctttggt aagaaagaag
     6721 aaagtttaga caatcttaaa ttacctaagt tcctctcaat cttccacgat acagttgttg
     6781 catctgctac cttgatgctc gtattcttcg gagccattct tttaatcttg ggtccagaca
     6841 ttatgtctaa taaagaagtc atcacttcag gaactctatt caatcctgct aaacaagatt
     6901 tctttatgta cattatccaa acagccttta ccttctcagt ttacttgttc gttttgatgc
     6961 aaggtgtccg aatgttcgta tctgagttga caaacgcctt ccaaggtatt tcaaacaaat
     7021 tgttgccagg ttcattccca gcggttgacg ttgcagcttc ttatggattt ggttctccaa
     7081 atgctgtctt gtcaggattt acctttggtt tgattggtca attgattaca attgttttgc
     7141 tcatcgtctt taaaaatccg attcttatta ttacaggatt tgtaccagtg ttctttgaca
     7201 atgcagccat tgcggtctac gctgataaac gcggcggatg gaaagcggct gttatccttt
     7261 cctttatatc aggtgtcctt caagttgctc taggagctct ttgtgtggcc cttctcgatt
     7321 tggcatctta tggtggctac catggaaata tcgactttga attcccatgg cttggatttg
     7381 gatatatctt caaatacctt ggtattgttg gttatgtact tgtgtgtctc ttcttgcttg
     7441 ttattcctca acttcaattt gccaaagcaa aagataaaga gaaatattac aacggtgaag
     7501 ttcaagaaga agcttagtat ctagaaaagg agaaataaaa tggttaaagt attagcagcg
     7561 tgcggaaatg gaatgggttc atcaatggtt atcaagatga aggttgaaaa tgctctccgt
     7621 aagcttaatc aaacagattt tacagtcaat tcatgcagtg tcggtgaagc taaaggttta
     7681 gcagtaggat atgacattgt aatcgcttct cttcatttga ttcaagaatt ggaagggcga
     7741 actaatggga agttaattgg gcttgataac ttgatggatg ataaagaaat caccgaaaaa
     7801 ctcagtcaag cactacagta aaaggttgga gggggctgga cagaaactga gagttatcgt
     7861 ttctgtccag ccccctcttt aaataaagga ggcagatatg aatttaaaac aagctttaat
     7921 tgacaatgac tcgatccgac taggtttaga ggctaacaat tggaaagaag cagtcaaggt
     7981 agcagtagat cccttgattg aaagtggggc aattttgcca gagtattacg atgctatcat
     8041 tgaatcgact gaagagtatg ggccttacta tatcttgatg ccaggtatgg ctatgcccca
     8101 cgctagacct gaagctggtg tgcaaagtga tgccttttca ttgattacct tacaaaatcc
     8161 tgttgtattt tcagatggga aagaggtatc tgttttgttg gcactagcag caacaagttc
     8221 aaaaattcac acaagtgtag ccattccaca aattattgcc ctgtttgaat tagaagattc
     8281 tattgcacgt ttacaggctt gccagactaa agaagatgtc ttggctatga ttgaagaatc
     8341 taaggatagc ccttatctcg aaggattgga tttggaaagt tagaaagagg aataaagaaa
     8401 tgacaaaaag aatacctaat ttacaagttg cattagacca ttcagacttg caaggagcga
     8461 ttaaagcagc tgtttctgtt ggtcaggaag tagatattat cgaagctgga actgtttgct
     8521 tgcttcaagt tggaagtgaa ctggctgaag tcttgcgtag ccttttccca gataagatta
     8581 ttgtggcaga cacaaaatgt gctgatgctg gtggaacagt tgctaaaaat aatgcggttc
     8641 gtggagcaga ctggatgact tgtatctgtt gtgcaaccat ccctactatg gaagcagctc
     8701 taaaggctat caagactgaa cgaggagaac gaggcgaaat ccagatcgag ctttatggcg
     8761 attggacttt tgaacaagct cagctttggc tagatgcagg tatctcacaa gctatttatc
     8821 accaatctcg tgatgctctt cttgctggtg aaacttgggg tgaaaaagac cttaataagg
     8881 ttaaaaaact cattgacatg ggcttccgtg tatctgtaac aggtggtcta gatgtagata
     8941 ctctcaaact ctttgaaggt gttgatgtct ttacctttat cgcaggtcgt ggaattacag
     9001 aggctgcgga tccagcagga gcagcgcgtg ccttcaagga tgaaatcaaa cgaatttggg
     9061 ggtaaatcat ggtacgtcca attggaattt atgaaaaggc aaccccaaca cactttactt
     9121 ggctagaacg tttaaatttt gccaaggagt taggctttga ttttgtcgag atgtctattg
     9181 acgaacgtga cgagcgttta gcaagacttg actggagtaa ggaagaacgc ttggaagttg
     9241 tcaaagaaat ctatgaaact ggtgttcgta ttccttctat ctgtttttca ggccatcgtc
     9301 gctacccatt gggttcaaaa gatccagttc tagaggaaaa atctctagaa ctcatgaaaa
     9361 aatgtatcga attagctcaa gacttgggag ttcgtacgat tcaattagct ggttacgatg
     9421 tttactatga ggaaaagtca ccccagacac gccaacgttt tatcaaaaat ttgagaaaag
     9481 cctgtgactg ggctgaagaa gctcaggtgg tacttgctat tgaaattatg gatgatcctt
     9541 tcatcaatag catcgaaaaa tatttggcta tagaaaaaga gattgactct cccttcctct
     9601 ttgtatatcc agatattggt aatgtgtctg catggcataa tgatatctat agtgagtttt
     9661 atcttggtca tcatgccatc gcagctctcc atctcaagga tacttatgca gtgacagaaa
     9721 gttcaagggg ccagttccga gatgtacctt ttgggcaagg ttgtgtcaaa tgggaagaag
     9781 ctttcgatat tttaaaggaa accaattata atggaccttt cctaatcgaa atgtggtctg
     9841 aaaattgtga aacagtagaa gaaacacgcg cagccattca agaggcgcaa gcttttctct
     9901 atccactcat taagaaagca ggtttgatgt aagatgaatc aagtaatcaa tgctatgcgt
     9961 aaacgagtct gtgatgccaa tcaatcattg ccaaaacatg gacttgtcaa atttacctgg
    10021 gggaatgtat ctgaagtcaa tcgcgaactc ggtgtcattg ttatcaaacc atcaggcgtg
    10081 gattatgacg aattgacacc tgaaaacatg gtagtgactg atctagatgg taagatccta
    10141 gaaggggatt taagaccatc ttccgacctc ccaactcatg tgcaattata taaggcttgg
    10201 tcagaaattg gtagtgtggt tcacacccat tcgacagaag ctgttgcttg ggctcaggca
    10261 ggtcgtgata ttcctttcta cggaacaacc catgcagatt atttctacgg ttcaatccct
    10321 tgcgcccgta gtttgaccaa ggacgaagta gaagtggcct atgaaaaaga tactggcctg
    10381 gttatcgtag aagagtttga acatcgcgga cttaacccgg ttgaagtacc aggaattgtt
    10441 gtacgcaatc acggtccatt cacctggggc aaaaatccag agaatgctgt ttatcactct
    10501 gtcgtactag aggaagtatc aaagatgaat cgctttacag aacaaatcaa tccaagagtt
    10561 ggacctgctc cccagtacat actagaaaaa cactaccaac gtaaacatgg accaaatgct
    10621 tattatggtc aaaagtaaga acgatgaagg aggagaaaaa gataaattta gctcctcttt
    10681 ttacatttga tttttattga gagtaaagtt ggagttgaag taattttaaa agatttttta
    10741 gaaatagcgc ttgatatata tatggtaaaa taaaaagaat tgctgtgata tcaatagatt
    10801 tgggggattt tttaatatgg tactggataa ggcaagttgt gatttgcttc aatatttgat
    10861 ggatcaagaa acgtccaaaa cgattatggc gatttcgaaa gatttgaaag agtcaagaag
    10921 gaaaatttat tatcacattg acaaaatcaa tgctgctctg ggtgacgagg cgcttcacat
    10981 cattagtatt ccacgaattg gtattcactt aacggaagag cagagagatg cttgttgtaa
    11041 actattatcg gaagtagatt cgtacgatta tatcatgagt gcgcatgaac gtatgatgat
    11101 aatgttacta tggataggta tttctaaaga acgtattacg attgaaaaat tgatagagtt
    11161 aacagaggta tctaggaata ctgttctcaa tgatttgaat agtattcgtt atcaactaac
    11221 tttggaacaa tatcaggtga tcttgcaagt gagcaagtca cagggatacc accttcatgc
    11281 ccaccctctt aataaaattc agtatcttca atcgcttcta tatcatattt ttatggaaga
    11341 aaatgccact tttgtatcta ttttagaaga taagatgaaa gagaggttag atgatgagtg
    11401 tttgctttct gttgaaatga accaattttt taaggaacag gttcctttag ttgaacaaga
    11461 tttagggaag aaaataaacc atcatgaaat aacttttatg ttgcaggttc taccttattt
    11521 gctgttaagc tgtcataatg ttgaacagta tcaagaaaga catcaggata tagagaaaga
    11581 attttctttg ataagaaaaa gaatagagta tcaggtgtct aagaaattag gagaacggtt
    11641 gtttcaaaag tttgaaattt ctttgtcagg acttgaagtt tctcttgtag ctgttctcct
    11701 cctctcctat cgtaaagatt tggatattca tgcagaaagt gatgattttc ggcaattaaa
    11761 acttgcttta gaagaattta tctggtattt tgaatcacaa atccgaatgg agattgagaa
    11821 caaggatgat ttgttacgaa atttgatgat ccactgtaaa gccttgttat ttagaaagac
    11881 ttacggtatt ttttctaaaa atcctctaac aaaacaaatt cgatccaagt atggagaatt
    11941 atttttagtc actagaaaat ctgcggaaat tttagaagga gcatggttta ttcggctaac
    12001 agacgatgat attgcctatt tgacgattca tattggagga tttttaaaat atacaccatc
    12061 atctcaaaaa aatatgaaaa aagtttatct cgtttgtgat gaaggtgttg cggtttcgag
    12121 acttttgctg aaacaatgca aactttattt tccaaatgag caaattgaca ctgtatttac
    12181 aacagaacaa tttaagagtg tggaagatat tgcacaagtt gatgtagtga ttactactaa
    12241 tgatgatttg gatagcagat ttccgatttt aagggttaat cctatccttg aagcagaaga
    12301 tattttgaaa atgctagact atcttaaaca caatatattt cgtaataaga gcaaaagttt
    12361 cagtgaaaat ctttctagtc ttatttcgtc ttatattgta gacagcaagt tggctagtaa
    12421 gttccaagaa gaggttcaaa cacttataaa tcaagaaata gtagttcaag cttttttgga
    12481 agatatttga aggacagtcc aatgatgaac acaaacctgt gtttttcttg gtctttttta
    12541 gtgttttgaa gggtggtata ctaatctcaa agataacaat tatatccaaa ggaggcaaca
    12601 tatgccaaac gtcaaagaaa ttacaagaga gtcatggatt ttagccactt tcccagagtg
    12661 gggaacatgg ttgaacgaag aaatcgaaga agaagtcgta cctgaaggca actttgccat
    12721 gtggtggcta ggcaactgtg gtacttggat taagacacca gctggtgcta acgttgtcat
    12781 ggacctttgg tcaaaccgtg gaaaatcaac caaaaaagtg aaagatatgg ttcgtgggca
    12841 ccaaatggca aatatggcag gtgttcgtaa gctgcaacca aacttgcgtg ttcagccaat
    12901 ggttatcgat ccatttgcta tcaacgaact agactattac ttagtttcac acttccacag
    12961 tgatcatatc gacccataca cagctgcagc aattctcaat aatcctaagt tagagcatgt
    13021 taagtttatc ggtccttacc actgtggacg aatctgggaa ggatggggtg ttccaaaaga
    13081 acgtatcatc gttgttaaac caggtgacac tatcgaatta aaagatatga agattcatgc
    13141 agtagaatca tttgaccgta cttgcttggt aactctccca gtgaacggtg ctgatgagac
    13201 aggcggtgaa cttgctggct tggctgttac agatgaagaa atggctcaaa aggctgttaa
    13261 ctatatcttt gaaacaccag gtggaaccat ctatcatggt gcagattctc acttctcaaa
    13321 ctattttgca aaacatggta aagactttaa aattgatgtt gctttgaata actatggtga
    13381 aaatccggta ggtatccaag acaaaatgac atctatcgac cttcttcgta tggcagaaaa
    13441 tctgcgtacc aaagtcatta tcccagttca ctatgatatc tggtctaact tcatggcttc
    13501 tactaatgag attctagaac tttggaaaat gcgaaaagat cgcttgcaat acgatttcca
    13561 tccatttatc tgggaagttg gcggtaagta cacttatcct caagatcaac acttagtaga
    13621 ataccatcat ccacgtggtt ttgatgattg ttttgaacaa gactctaaca ttcaatttaa
    13681 agctttgcta taatataaaa atattctttg gaggttatcc gtatgttgca tgatacggat
    13741 aattttcata taatagtaaa atagaatgtg tgattcaata atcacctcaa atagaaagga
    13801 aattctatgt caaatctatc tgttaatgca attcgttttc taggtattga cgccattaat
    13861 aaagccaact caggtcatcc aggtgtggtt atgggagcgg ctccgatggc ttacagcctc
    13921 tttacaaaac aacttcatat caatccagct caaccaaact ggattaaccg cgaccgcttt
    13981 attctttcag caggtcatgg ttcaatgctc ctttatgctc ttcttcacct ttctggtttt
    14041 gaagatgtca gcatggatga gattaagagt ttccgtcaat ggggttcaaa aacaccaggt
    14101 cacccagaat ttggtcatac ggcagggatt gatgctacga caggtcctct agggcaaggg
    14161 atttcaactg ctactggttt tgcccaagca gaacgtttct tggcagccaa atataaccgt
    14221 gaaggttaca atatctttga ccactatact tacgttatct gtggagacgg agacttgatg
    14281 gaaggtgtct caagcgaggc agcttcatac gcaggcttgc aaaaacttga taagttggtt
    14341 gttctttatg attcaaatga tatcaacttg gatggtgaga caaaggattc ctttacagaa
    14401 agtgttcgtg accgttacaa tgcctacggt tggcatactg ccttggttga aaatggaaca
    14461 gacttggaag ccatccatgc tgctatcgaa acagcaaaag cttcaggcaa gccatctttg
    14521 attgaagtga agacggttat tggatacggt tctccaaaca aacaaggaac taatgctgta
    14581 cacggcgccc ctcttggagc agatgaaact gcatcaactc gtcaagccct cggttgggac
    14641 tacgaaccat ttgaaattcc agaacaagta tatgctgatt tcaaagaaca tgttgcagac
    14701 cgtggcgcat cagcttatca agcttggact aaattagtta cagattataa agaagctcat
    14761 ccagaactgg ctgcagaagt agaagccatc atcgacggac gtgatccagt cgaagtgact
    14821 ccagcagact tcccagcttt agaaaatggt ttttctcaag caactcgtaa ttcaagtcaa
    14881 gatgccttga atgttgtggc agctaaatta ccaacctttc taggtggatc agctgacctt
    14941 gctcactcaa acatgactta tatcaagacg gatggacttc aagacgatgc caatcgcttg
    15001 aatcgtaaca ttcagtttgg tgttcgtgaa tttgcaatgg gaacaatctt gaacgggatg
    15061 gcccttcatg gtggacttcg tgtatacggt ggaactttct tcgtcttctc tgactatgtg
    15121 aaggcagctg tccgcttgtc agccttacaa ggacttcctg tgacttatgt ctttacccat
    15181 gattcaatcg cagttgggga agatggtccg actcatgaac cagttgagca tttagcaggt
    15241 cttcgtgcta tgccaaatct aaatgttttc cgtccagcag atgcgcgtga aacgcaagca
    15301 gcttggtacc ttgcagtgac aagtgagaaa acaccaactg cccttgtctt gacacgtcaa
    15361 aatttgactg ttgaagatgg aacagacttc gacaaggttg ctaaaggtgc ttatgttgta
    15421 tatgaaaatg cagccgactt tgataccatc ttgattgcga caggttcaga ggttaatctt
    15481 gctgtctcag ctgctaaaga attggctagt caaggcgaaa aaatccgcgt agtcagcatg
    15541 ccatctacag atgtctttga taaacaagat gcagcttaca aggaagaaat tcttccaaat
    15601 gcagtccgcc gtcgtgttgc agtcgaaatg ggtgcaagtc aaaactggta caaatatgtt
    15661 ggtctcgatg gtgccgttct aggtattgat accttcggag cctctgcccc agcaccaaaa
    15721 gtattggcag aatatggctt tactgtagaa aatcttgtaa aagttgttcg aaacttgaaa
    15781 taatcctaaa aatcagggcg taagctctgg tttttcttac cagaaaagta aggtacaatc
    15841 ttgtaaaagt agctgaaatt tgatatagta gtcctatgta aaagacaaag gagaaaacaa
    15901 tgaatccaaa tattactttt ttaatcatgc ttgtaggtat gatggccttg atgttcttta
    15961 tgcaacgttc tcaaaagaaa caagctcaaa agcgtatgga aagcttaaat aaactacaaa
    16021 aaggctatga agtgattaca atcggtggac tttatggaac agtcgatgaa gtagatacgg
    16081 agaagggaac aatagttctt gacgtagagg gagtttactt gacttttgaa ctagctgcta
    16141 tcaagacagt attaccgctg aaagaaacag cttcactaga aggcgcaatt gaaaaataag
    16201 acgggatcac gaactcccgt ttttctataa aagaaaggaa atgggatgaa aaaattagtc
    16261 tttgtctgtc tgggaaatat ttgccgtagc cctatggccg agtttgttat gaaatcaatg
    16321 acagataact acgaaatcca aagtcgagca acttcctctt gggaacatgg caatccgatt
    16381 cataagggga ctcagggaat ttttcaagag tatgagattc cttatgacaa gaacaagaca
    16441 tcgcttcaga ttagtaagga agattttgaa gcctttgatt atattatcgg aatggacgct
    16501 tcaaatattt ctgacttacg tcagatgtgt ccagtagact gtcaagataa gatttactca
    16561 ttttcatctg aaagtgttcc agacccttgg tatacaggag attttgaaga aacctatcga
    16621 cgtgttcaag agggctgtca agcttggtta gaacgtttag aaaaggagag ttaaggtgga
    16681 aaatcttacg aatttttacg aaaagtatcg tgtctatctg actcgtccac gtttagagct
    16741 tttggcagta gttaccattg ttttctgtgc tgtactcgtc ttttttctaa atattccagg
    16801 aaaaggtgtc ttaaaactcg ataatggaac gattgtttat gatggcagtc ttgtccgcgg
    16861 taaaatgaat ggccaaggta ccattacctt ccaaaatgga gaccaatata caggtggctt
    16921 caacaatgga gccttcaacg gaaaaggtac ctttcaatct aaagaaggct ggacctacga
    16981 aggtgatttt gtaaatggtc aggctgaagg aaaagggaaa ctaacaacag aacaagaagt
    17041 cgtttatgaa ggaactttta aacaaggcgt ttttcaacaa aaataaagcc tccttatcaa
    17101 aggaggtatt attagaatcg caaggtaagc gcttacctgc aaatcccttt ctttccaaat
    17161 ccctcttcca agcaagtttg tgaaataaaa aatatttgaa ataaatttca caaacttcaa
    17221 agataaaacc tgataagaaa agaaaatgag aaaagtttca caagagttta aaaattcttt
    17281 gtgaaatgtt tatgaaactg tttacaaagt tgaaataatg cgttataata aacttgtgaa
    17341 aaaattaaca aaggatatcg ttccttgaaa gctatggagg aaaatatggc tgataaaaaa
    17401 actgtgacac cagaggaaaa gaaactcgtt gctgaaaaac acgtagatga gttggttcaa
    17461 aaagctctag ttgcccttga agaaatgcgt aaattggatc aagaacaagt tgactacatc
    17521 gttgccaaag catcagtagc agctttggat gcccacggag aattggcttt acatgccttt
    17581 gaagaaacag gacgtggtgt atttgaagat aaagcaacta agaacttgtt tgcttgtgaa
    17641 cacgtggtaa acaacatgcg tcacactaaa acagttggcg ttatcgaaga agatgatgta
    17701 acaggattga ccctgattgc tgaaccagtt ggtgttgttt gtggtatcac tccaacaaca
    17761 aacccaacat caacagcgat cttcaaatca ttgatttcat tgaagacacg taatccaatc
    17821 gtctttgcct tccatccatc agctcaagaa tcatcagctc atgcagctcg tatcgtccgc
    17881 gatgcagcta tcgcagctgg tgctcctgaa aactgtgtac agtggatcac tgaaccatct
    17941 atggaagcaa ctagtgccct tatgaaccac gaaggtattg caacaatcct tgcaacaggt
    18001 ggtaatgcca tggttaaagc cgcatactca tgtggtaaac cagctcttgg ggtaggtgcc
    18061 ggaaacgttc cagcttatgt tgaaaaatca gcaaacattc gtcaagcagc acacgatatc
    18121 gtcatgtcta aatcatttga taacggtatg gtctgtgcat ctgaacaagc agttatcatt
    18181 gataaagaaa tttacgatga atttgtagca gagttcaaat cttaccacac ttactttgta
    18241 aacaaaaaag aaaaagctct tcttgaagag ttctgcttcg gcgtcaaagc aaacagcaaa
    18301 aactgtgctg gtgcaaaatt gaacgctgac atcgttggta aaccagcaac ttggattgca
    18361 gaacaagcag gatttacagt tccagaagga acaaacattc ttgctgcaga atgtaaagaa
    18421 gttggcgaaa atgagccatt gactcgtgaa aaattgtcac cagttattgc agttttgaaa
    18481 tctgaaagcc gtgaagatgg tattactaag gctcgtcaaa tggttgaatt taacggtctt
    18541 ggacactcag cagctatcca cacagctgac gaagaattga ctaaagaatt tggtaaagct
    18601 gttaaagcta ttcgtgttat ctgtaactca ccttctactt ttggtggtat cggggacgtt
    18661 tacaatgcct tcttgccatc attgacactt ggatgtggtt cttacggacg caactcagtt
    18721 ggggataacg ttagtgccat taacctcttg aatatcaaaa aagtcggaag acggagaaat
    18781 aacatgcaat ggatgaaact tccttcaaaa acatactttg aacgtgattc aattcaatac
    18841 cttcaaaaat gtcgtgacgt tgaacgtgtc atgatcgtta ctgaccatgc catggtagag
    18901 cttggtttcc ttgatcgtat catcgaacaa ctggaccttc gtcgcaataa ggttgtttac
    18961 caaatctttg cggatgtaga accggatcca gatatcacaa ctgtaaaccg tggtactgag
    19021 attatgcgtg ccttcaaacc agataccatc atcgcactcg gtggtgggtc tccaatggat
    19081 gctgccaaag taatgtggct cttctacgag caaccagaag tggacttccg tgaccttgtc
    19141 caaaaattca tggatatccg taaacgtgcc ttcaagttcc cattgcttgg taagaagact
    19201 aaattcatcg cgattccaac tacatctggt acaggatctg aagtaacacc atttgccgtt
    19261 atctctgata aagcaaacaa ccgtaaatac ccaatcgctg actactcatt gacaccaact
    19321 gtggcaatcg tagatcctgc tttggtattg acagttccag gatttgttgc tgctgatact
    19381 ggtatggacg tattgactca cgcgacagaa gcatacgtat cacaaatggc tagtgactac
    19441 actgatggtt tagcacttca agccattaaa ttggtctttg aaaatctcga aagctcagtt
    19501 aagaatgcag acttccactc acgtgagaaa atgcataacg cttcaacaat cgctggtatg
    19561 gcctttgcca atgccttcct aggtatttct cactcaatgg cccataagat tggtgcgcaa
    19621 ttccacacaa tccacggtcg tacaaatgct atcttgcttc catacgttat ccgttacaac
    19681 ggtacacgtc cagctaagac agcaacatgg cctaagtaca actactaccg tgcagatgaa
    19741 aaataccaag atatcgcacg catgcttgga cttccagctt ctactccaga agaaggggtt
    19801 gaatcttacg caaaagctgt ctacgaactc ggtgaacgta ttgggatcca aatgaatttt
    19861 agagaccaag gaattgacga aaaagaatgg aaagaacatt ctcgtgaatt agccttcctg
    19921 gcttatgaag accaatgttc accagctaac ccacgtcttc caatggtaga ccatatgcaa
    19981 gaaatcatcg aagatgcata ctatggctac aaagaaagac caggacgccg taaataattg
    20041 tttatcagtc tagaagcaag acaaaaactc aatttgaggg aaagatccag taatttttct
    20101 atgataaaag gcatcctatc aaggtttttg aacacctgat aggatgcctt tttatgatat
    20161 tgaggccttt ttgccctttt tgaaaaacta gaatagaaac aaaatatata atagattgaa
    20221 actggaatag tacacttctg cttctaaaac attgttagaa ttcgatttga ctgtcctgat
    20281 cgatttgtcc tattcctatt tcattttact atataaaaaa tatagtatag tagactgaat
    20341 ctaaaatagt acgaaacaat tgctaaaaca tttatagaaa ttaattttac tttcctgata
    20401 gagttgttca catcttattt caattcacta tagtttaatt taagagtagt atttactaag
    20461 gcccaattaa aatcaaagag caaactagaa aacgagtgcc attcagctca aaacactgat
    20521 ttgagattgc agataagact agcccctcat taacaggttt acgataaaac gatgacaagg
    20581 tgtgttgctt tttgatttct aaagagtata atgatagatc tctataaaat aagtgcgaag
    20641 gaaatgagct tttatagtcc tttcgtttta aaatactatc tcagatgttc ttatatcgac
    20701 aagaagtttt tgagtcattc cctcatcata catattaaat aaatagtggc tcattcaatt
    20761 ttttactaga ataataagct agtatagtaa actgaaataa gatataaaca aataaattgg
    20821 agcttaacat ctatttccag caatttttta gaaactgcag tggactattc taaattcaac
    20881 acattataaa aactagagta aaagaaaagg attggatctt gtgtaatgca ggatctaatc
    20941 ctttcaatca ttttgtccaa cttttggagg ttcctacaat gtagccgtca ttaataaaga
    21001 cagatgggaa cgacagtgtt cctatttatt ttgatagaga tcgatgaatt ctttagatag
    21061 caactgaata atctctgttg aagccatttg gtcttctgca tgcataaata gcaaggagaa
    21121 tcctattttt tctccagtag cttctttttg tatgagatta gagtgaatct tgtgcgcttc
    21181 tactaaggag tcttccgctt cttcaacttt aattttcgct tcttttaaat ttcctgcctt
    21241 agctagttgg atggcttcaa taaaggatga tttggctgct ccactattgg caatgagctg
    21301 aaaacagata tattccattt cttctgtcat cttatttctc ctatccatgc aagtgcttgt
    21361 tccagaactt ttgctccatt catcattccg taatcccgca tatcaatggt atctacaggg
    21421 atatttcctg caatttcttt cacagcaagt aactcataac gaatttgtgg cccaattaga
    21481 atgacatctg cttcatggat attctttttc gcttctgtca ttgattttgc ttggatagaa
    21541 atttcaatcc cacgttcagt cgcactttgt tgcatttttt taacaagcat acttgtcgac
    21601 attcccgcat tacatactaa taaaatttgt ttcataatct taaccttcca tttcttgctc
    21661 aacaactttg tcattaactt tgataaatgg aatgtataga agaactccaa gtgcaaagat
    21721 gatgaattga actagaactg ctctcacgtc ccctgctgtt gctaaccatg catttaagaa
    21781 tactggtgta gtccaaggaa cttgtataaa tgcaggactc atgaatcctg taactgttgc
    21841 taagtagctg attaaaatac caaggactgg aactgtgata aatggaatag ctaatgaaat
    21901 gttataaacg attgggtaac cgaataatac tggttcattg atattgaaga taccaggtcc
    21961 aaaagataat ttagccacgt ttttagaaac agcattgcga ctcactaaga atgttgctat
    22021 taataaacat aatgtagatc cactaccacc cattaaagcg aatgtttgta tttgtgataa
    22081 gttgatgatg tgtggaatgg cttgtccatt atttgctgca gtgatgtttt cagtaatgtt
    22141 aattaatagt aatggttcta ggatggcact gtaaataact gcttggtgaa taccaaatag
    22201 ccataacata tttcctaaag agtaaataat aatgaccccg attaagcttg taccaatatg
    22261 acgaattggt tcttgaataa agattgtaat gattgagatt aagttcattc cagttatatt
    22321 gaataataat gctgaaacaa tcccaaataa ggagatgaca gtcatgactg gaagtaatac
    22381 gctaaatgat ctactaacag ctggtggaat attttcacca aggttcattt gtaaagcttt
    22441 aacgtttgat aattcaatga ataattctgt tgcaataatc gctacgataa ccccggcgaa
    22501 cattgcgcct gtacctgtgt tgttgaatga aagaacacct gaaatgttta cagcatcttt
    22561 tgctccgtca ggaactacag aaactgtatt tggcatcatc acaattaaag aaactaatga
    22621 tagcattgat gctgctgacg ggttttcgaa atctctgttt ttagctaaga aataaccaac
    22681 cattacagca ataatcatac ctgaaatact taaagtaccg tttgcaattg ttattcccca
    22741 atattggaat tttgttaatg tatccccttg gaaaatccac ttaaataccg tgttgttcaa
    22801 aagaacgatt aaacctgcca aaatatataa tggcattact gttacgaatg catctcttag
    22861 ggtttttaaa tgaatttggt tccctagttt accagcaaag gtggcaaatt gatctataaa
    22921 ttttgagttt ttcatctgaa tatctcctct ctttactcct caatttctac ttcaaaaccg
    22981 ttattgtcac ttactttgcg ataccatctt cctgagctct tgatggttct cttttgcgtt
    23041 tctaaatcaa cggagataaa tccgtaacga ttcttatatg cattattcca agaccagcaa
    23101 tcaaatgcgg tccaagcgtg gtatccaaaa cagagacttc cctcttcaat ggctttatgt
    23161 agccatctta aatgttcttc ataaaattca atacgataca cgtcatcgat aactccattt
    23221 tcatcgataa accgtgcttc gttttcaaca cccattccgt tctcactgat aaaccatggg
    23281 atattaccat attcttcctt cacaatcata gcaatatcat aaatggcttt cggaaaaatt
    23341 tcccaaccac gatatggatt catgcgacgc tccggccatt catactcttt gaagtattgg
    23401 tctggcatcc agggcgtctg atattcctca ggatttgctt gtgcttgaac acgttttgga
    23461 tggtagtagt ttactccaag aaaatcaacc gtatttgatt tcatcagttg aagctctttt
    23521 tcggtatgac tccataacac gccatctctc tctagctgtt ttaccaatct ttctgggaaa
    23581 gttcctttaa cagctggatt caagaagact ttgttaaaga agtcttctgt aaatcgactt
    23641 gcttctaagt cttctggaga attacttctt ggataagcag gtgtcaagtt taaaataatc
    23701 ccaatctttc catcaagtcc taatgagcga tatagttgaa tcacttttgc actagcaagg
    23761 tttagattat agatgacttg tacggcctct tttccctttc cttttagatt tggataatgg
    23821 aaagcatata agtatcctgc ttctggaatg accattggct cattgaaagt tgtccagtaa
    23881 tgaaccttat ctccaaagca tgtgaaagca gtcttggcaa acttcacgaa taactccact
    23941 acatgtttgc tttcccaacc accgtatttt tgaagaagtt ccactggtaa atcaaaatga
    24001 tgtaaattca tcacaagatc catctggttc tttttagctt cttcaatgat ggcattgtag
    24061 aaagcaatac cttttggatc aggctcacct gtctctaaat tcttgatgag tcgactccat
    24121 tggatggaag tgcggaaaga attaactcca atttccttca tcaagtggaa atcttcggtg
    24181 taagtatgaa aaaagttact ggctacaaga ggtccgacat tatcgaaaaa atcttctgga
    24241 tgcgttttga accagtagtc catcacattt tcatgtactt ttccatattg accttctgtc
    24301 tgaggtccgc tagaagcagc tccccaccaa aacagattag gaaatactaa cttttttttc
    24361 atgctcaacc tcctttctat tatgctatac ataaagtata gcataatttt aaaatttgtc
    24421 tagacatttt taaaaattgt tgatacatat attgtgtttg cctcatttct tgaactttgt
    24481 tatactacta ttagaatatt atagagagaa ccagattaaa tgagtacaaa atatttattt
    24541 atttacaatg agattcgtga aaagattctc tgtaataaat ataccatgaa cgaacaattg
    24601 cctgatgaaa tgacattagc taaacagttt gcctgtagtc gaatgacgat caaaaaagct
    24661 ttagacttgt tagtttctga gggcttaatt tttagaaaac gtgggcaggg aacctttgtt
    24721 ctctctcgtg gcagctcaaa aagaaaatta atcgttccag aaagagatat ccggggactg
    24781 acaaaaatat ctgaagatgc tcattctaca attgactcga ggattattca cttcaaatta
    24841 gaatttgcaa atgaattttt agcagaaaaa ctacaggtcg ctttgcagag tccagtttat
    24901 aatatttacc gcctgcgtat tattgacggt aaaccttatg ttctggaaca aacttatatg
    24961 agtaccgatg ttattccagg tattactgaa gatattttac aaaaatcgat ttacaattac
    25021 attgaaggaa agttaggatt gcatattgcc agtgctacaa aaatcttgcg agcttcttct
    25081 agttcagaaa atgagcaaca ttacttgcag ctccttccaa cagaaccggt atttgaagta
    25141 gaacaagtgg cttatttgga taacggaact ccgtttgagt actcgattag tcgtcatcgc
    25201 tatgatttat ttgaatttaa ttcttttgca ttacgacatt cctcctagga gaaaatgtga
    25261 aaatgaagcc aatcttttac aggctctagt ttaagaaaaa tttaaaacag ggcaagaagg
    25321 tcccatctat gcttaaatgg tttctctttt ctaaataaga tggctttaaa agagtgatcg
    25381 ttttatccat catgttgaaa aatatcttcg tatagcttat agagtaggta ctgaaattgt
    25441 tcacctgatc tacttcttat agttatttag ttttaaatag tgtttcaaac attcttacac
    25501 tgacgagaag tttttgagtc ttttcttgta acacatatag tatactgagg ttagaatagt
    25561 agactgtgac ttctaacaaa ttgctagaaa tgaatttcaa tctcccaatt tatttgctta
    25621 tatattattt taatatatta aataaattct ggatcataat catttaaaaa aattttattt
    25681 ttttattttt cattacgaat aatatagatg aaggggaaag agtatgaaaa cagaactgtt
    25741 tcttttgcta ttagttcaaa aggagaaaaa atgaaagtag aaaatatttc gtatagggtg
    25801 gatcatcgta tattgtttga taatatttct tttgatactt cgagttcaga cgtgacatta
    25861 attactggta aaaatggtac aggaaagtca actttactat agtggattga aactagaata
    25921 gtacacatct acttctaaaa tattgttaga aatcgatttg actatcctga tctatttgtc
    25981 ctgttcttat ttcatttcac tatatctcaa attgagtatg acgaagtgcg ctcccatgtc
    26041 ctgggaacgc actttcttca tatttttcat attcttgaat ccatcgataa agactattgg
    26101 gatgaatttt taaagttgaa ctaatcattt ttacaggatg aggtttacag cagagagttt
    26161 gaaggcttta tcaaaggttt ttcttggcat aatgactttt cctcgtttcc acttaatttt
    26221 gtgtctactt tattatacca agtccaccct taagttagat aataaatcta acttaaggaa
    26281 gctagaagga tgagaatcca ggtggtcaag agtcccaaac ttaagctgat tgggacaccc
    26341 agaataattt gctttttgaa ggcaaggcca cgttcctcta tattgggaag tgagagttga
    26401 atgagagaac cagctgatga aaagggtgag atattagtag atagagcgcc aataacggtg
    26461 gctgttgtga gtaagtgaat atcaatctgg ggattttgag cactgatgat agcaatgatg
    26521 ggaaagaggg ctggagctac aacggatagg gtggaactaa agagtgacat caccccggct
    26581 atcacacaaa agaacagagg taaccagaaa tgaggaatgg atgttgtcat gaggtgccct
    26641 atcagtgtga ctaaacctga cttgaccgct agagacatta gtaagctcat gccgcagagc
    26701 atgataattg tagcccaggg aactttagcc aaaatggctt cttgcttccc taatttgagc
    26761 cttaaggcga ggcagaccat gagtattgag acaaagccaa tatcaaatgt ttttcgataa
    26821 gtagctatcc aggcgatgtt tgggaaaatg agatgcaaca agggaaaaag ccaaaccaaa
    26881 accatgctgc tgatcatgag caaggtggtt tgtctttgaa ccttgctgag gagtggtggt
    26941 tggtcaatag tcaaggatga gtttgttctt cccttactat agtgactgta acaggataat
    27001 aaaagcaaga caatgagtgg gtagataatg ctgacgataa agatatgatt gccaagtgaa
    27061 aaagcttgct cttcccatcc catttgctta aacaggcctt gaaagacaat gcctgagcta
    27121 ctggttatca aattagcccc tcctgaagct ccccaattga cggcttgagc tccaatcaaa
    27181 gggtgtttgt ccgctttttg acagagagta atcgctagag gacagcaaac ggccatagta
    27241 gtgaaaaatc cagcacctaa agcagacaaa agggttgcca tcaggtataa aatcatgtag
    27301 agggcgttag ggtaggtgcg tgtgcggtag agaatgtgtt gagccaaaac atcaagagta
    27361 ccgttagtta ttgcaaagtt ataaaagaga gagacgctaa aaatggtaaa aaagagtgag
    27421 gttggccaaa aatgaagaag ttctttgggg cttaatccca tgagagtggt tgcgatgagg
    27481 taagaaaaag caatagccag caggccaata ttgattttgg tgcggtaacc aattccaatg
    27541 gctagagcaa tggcgctaat cattattaaa tgaatcattg aattgtcctt tcagttagaa
    27601 tatggaaata ggttggcaat tttggcgctc aaaagaccac ctgtttccta ttggtacttg
    27661 actattatac acaaaaaaaa tacaattgtc ttgacaattg tattgacact tgttagaatt
    27721 aaaaatgagg tattcaggct tgtgatttcc tatggaagtt aatagtgatt gcctctaatg
    27781 cttacaagtg atattaaaaa tagaggacct agtgatgtca atcatttcaa ctgatttaac
    27841 cccttttcaa atagatgata cattgaaagc agccttgcga gaagatgttc attccgaaga
    27901 ttacagtacc aatgccattt ttgatcatca tggccaagcc aaggtgtcgc tttttgccaa
    27961 ggaagctggt gttttagcgg ggctaaccgt ttttcaaagg gtttttaccc tatttgatgc
    28021 cgaggtgacc ttccagaatc ctcatcaatt taaggatggg gatcgtttga ctagtggcga
    28081 tttggtttta gaaatcatag gctcggtgag aagtctctta acatgtgaac gcgttgcctt
    28141 gaatttttta caacatttat cagggattgc ttcgatgaca gctgcttatg tagaagcctt
    28201 aggcgatgat tgcattaagg tatttgatac tcgaaaaact actcctaatt tacgtctttt
    28261 tgagaaatat gcagtgagag ttggcggtgg ctataatcat cgctttaatt tatcagatgc
    28321 tatcctgcta aaagacaatc acattgcggc agtaggtagt gttcaaaagg caattgctca
    28381 agcgcgtgcc tatgcccctt ttgtgaaaat ggtcgaggtg gaagtggaaa gccttgctgc
    28441 tgccgaagaa gctgcggcgg cgggtgctga tattatcatg ttggataata tgtcattgga
    28501 acagattgaa caggccatta ccctaattgc aggacgttct cggattgaat gttctggaaa
    28561 tattgatatg accactatta gccgttttcg tggtttagcg attgattacg tctccagtgg
    28621 tagtttaacc catagtgcta agagtcttga tttttccatg aaggggttaa cctaccttga
    28681 tgtctaagtt gtaaaataaa ctaacttttt aaaggatgtc tttcctctag aacgagtttt
    28741 atgtcagata gtttaaacgc ctctt
//
LOCUS       DAVBEO010000026        28647 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 009
            SAMEA1678075-rid20185393.denovo.026, whole genome shotgun sequence.
ACCESSION   DAVBEO010000026 DAVBEO010000000
VERSION     DAVBEO010000026.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678075
            Sequence Read Archive: ERR226392
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 28647)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 28647)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980207.1
            Genome Coverage       :: 150x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:50:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 72 of 147
            Pseudo Genes (incomplete)         :: 72 of 147
            Pseudo Genes (internal stop)      :: 42 of 147
            Pseudo Genes (multiple problems)  :: 32 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..28647
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678075-rid20185393.denovo.026"
                     /strain="KS 009"
                     /db_xref="taxon:1313"
     gene            complement(512..2239)
                     /gene="ezrA"
                     /locus_tag="VQ543_001151"
     CDS             complement(512..2239)
                     /gene="ezrA"
                     /locus_tag="VQ543_001151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000064817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septation ring formation regulator EzrA"
                     /protein_id="HET2611879.1"
                     /translation="MSNGQLIYLMVAIAVILVLAYVVAIFLRKRNEGRLEALEERKEE
                     LYNLPVNDEVEAVKNMHLIGQSQVAFREWNQKWVDLSLNSFADIENNLFEAEGYNHSF
                     RFLKASHQIDQIESQITLIEEDIAAIRNALADLEKQESKNSGRVLHALDLFEELQHRV
                     AENSEQYGQALDEIEKQLENIQSEFSQFVTLNSSGDPVEAAVILDNTENHILALSHIV
                     DRVPALVTTLSTELPDQLQDLEAGYRKLIDANYHFVETDIEARFHLLYEAFKKNQENI
                     RQLELDNAEYENGQAQEEINALYDIFTREIAAQKVVENLLATLPTYLQHMKENNTLLG
                     EDIARLNKTYLLPETAASHVRRIQTELESFEAAIVEVTSNQEEPTQAYSVLEENLEDL
                     QTQLKDIEDEQISVSERLTQIEKDDINARQKANVYVNRLHTIKRYMEKRNLPGIPQTF
                     LKLFFTASNNTEDLMVELEQKMINIESVTRVLEIATNDMEALETETYNIVQYATLTEQ
                     LLQYSNRYRSFDERIQEAFNEALDIFEKEFDYHASFDKISQALEVAEPGVTNRFVTSY
                     EKTRETIRF"
     gene            complement(2321..4267)
                     /gene="gyrB"
                     /locus_tag="VQ543_001152"
     CDS             complement(2321..4267)
                     /gene="gyrB"
                     /locus_tag="VQ543_001152"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002283665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase (ATP-hydrolyzing) subunit B"
                     /protein_id="HET2611880.1"
                     /translation="MTEEIKNLQAQDYDASQIQVLEGLEAVRMRPGMYIGSTSKEGLH
                     HLVWEIVDNSIDEALAGFASHIQVFIEPDDSITVVDDGRGIPVDIQEKTGRPAVETVF
                     TVLHAGGKFGGGGYKVSGGLHGVGSSVVNALSTQLDVHVHKNGKIHYQEYRRGHVVAD
                     LEVVGDTDRTGTTVHFIPDPKIFTETTTFDFDKLNKRIQELAFLNRGLQISITDKRQG
                     LEQTKHYHYEGGIASYVEYINENKDVIFDTPIYTDGEMDDITVEVAMQYTTGYHENVM
                     SFANNIHTHEGGTHEQGFRTALTRVINDYARKNKLLKDNEDNLTGEDVREGLTAVISV
                     KHPNPQFEGQTKTKLGNSEVVKITNRLFSEAFSDFLMENPQIAKRIVEKGILAAKARV
                     AAKRAREVTRKKSGLEISNLPGKLADCSSNNPAETELFIVEGDSAGGSAKSGRNREFQ
                     AILPIRGKILNVEKASMDKILANEEIRSLFTAMGTGFGAEFDVSKARYQKLVLMTDAD
                     VDGAHIRTLLLTLIYRYMKPILEAGYVYIAQPPIYGVKVGSEIKEYIQPGADQEIKLQ
                     EALARYSEGRTKPTIQRYKGLGEMDDHQLWETTMDPEHRLMARVSVDDAAEADKIFDM
                     LMGDRVEPRREFIEENAVYSTLDV"
     gene            complement(4282..4845)
                     /locus_tag="VQ543_001153"
     CDS             complement(4282..4845)
                     /locus_tag="VQ543_001153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HET2611881.1"
                     /translation="MKYHDYIWDLGGTLLDNYETSTAAFVETLALYGITQDHDSVYQA
                     LKVSTPFAIETFAPNLENFLEKYKENEARELEHPILFEGVSDLLEDILNQGGRHFLVS
                     HRNDQVLEILEKTSIAAYFTEVVTSSSGFKRKPNPESMLYLREKYQISSGLVIGDRPI
                     DIEAGQAAGLDTHLFTSIVNLRQVLDI"
     gene            complement(4930..5484)
                     /locus_tag="VQ543_001154"
     CDS             complement(4930..5484)
                     /locus_tag="VQ543_001154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DJ-1/PfpI family protein"
                     /protein_id="HET2611882.1"
                     /translation="MVKVAVMLAQGFEEIEALTVVDVLRRANITCDMVGFEEQVTGSH
                     AIQVRADHVFDGDLSDYDMIVLPGGMPGSAHLRDNQTLIQELQSFEQEGKKLAAICAA
                     PIALNQAEILKNKRYTCYDGVQEQILDGHYVKETVVVDGQLTTSRGPSTALAFAYELV
                     EQLGGDAESLRTGMLYRDVFGKNQ"
     gene            complement(5495..6718)
                     /locus_tag="VQ543_001155"
     CDS             complement(5495..6718)
                     /locus_tag="VQ543_001155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000830656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HET2611883.1"
                     /translation="MKRSLDSRVDYSLLLPVFFLLVIGVVAIYIAVSHDYPNNILPIL
                     GQQVAWIALGLVIGFVVMLFNTEFLWKVTPFLYILGLGLMILPIVFYNPSLVASTGAK
                     NWVSINGITLFQPSEFMKISYILMLARVIVQFTKKHKEWRRTVSLDFLLIFWMILFTI
                     PVLVLLALQSDLGTALVFVAIFSGIVLLSGVSWKIIIPVFVTAVTGVAGFLAIFISKD
                     GRAFLHQIGMPTYQINRILAWLNPFEFAQTTTYQQAQGQIAIGSGGLFGQGFNASNLL
                     IPVRESDMIFTVIAEDFGFIGSVLVIALYLMLIYRMLKITLKSNNQFYTYISTGLIMM
                     LLFHIFENIGAVTGLLPLTGIPLPFISQGGSAIISNLIGVGLLLSMSYQTNLAEEKSG
                     KVPFKRKKVVLKQIK"
     gene            complement(6755..9205)
                     /locus_tag="VQ543_001156"
     CDS             complement(6755..9205)
                     /locus_tag="VQ543_001156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional DnaQ family
                     exonuclease/ATP-dependent helicase"
                     /protein_id="HET2611884.1"
                     /translation="MKTIGNRYVVVDLEATSTGSKAKIIQVGIVVIEDGEIVDHYTTD
                     VNPHEPLDAHIKELTGLTDQRLAQAPDFSQVARKIFDLVEDGIFVAHNVQFDANLLAE
                     NLFFEGYELRNPRVDTVELAQVFFPELEKYSLPILCRELGIPLKHAHTALSDAQATAE
                     LLLFLREKMTQLPKGLLERLLEMADALLYESYLVIEETYRNQSILSSPDLVQVQGLYF
                     KKTAASLEPRKLSQDFSKNISLLNLEVREEQESFAKEVGLLLKDEPVSLIQAPTGIGK
                     TYGYLLPALSQSKERQIVLSVPTKILQNQIMEEEGKRLKEVFHTDIHSLKGPQNYLKL
                     DAFYHSLQENDENRLFRRFKMQVLVWLTETETGDLDEIGQLYRYQHFLADLRHDGNLS
                     SQSLFVTEDFWKRSQERAETCKLLVTNHAYLVTRLEDNPEFVSDRLLIIDEVQKILLA
                     LENLLQETYDIQSIIDLIDKALVGEENRVQQRILESIRFECLYLIEQFQSGKSRKNIL
                     DSLDNLHQYFSELEVEGFDELVRYFTAEGDYWLEVTETSQKKIQISSTKSGRTLLSSL
                     LPESCQAMGVSATLEISQRVSLADLLGYPEAKFVKIESRGKQEQEVVMVKDFPLVTET
                     SLEVYAREVAALLVEIQAFQQPILVLFTAKDMLLAVSDLLTVSHLAQYKNGDVHQLKK
                     RFEKGEQQILLGAASFWEGVDFSSHPFVIQVVPRLPFQNPQEPLTKKINQELNQEGKN
                     AFYDYQLPMAIIRLKQALGRSMRREYQRSLTLILDRRIIGKRYGKQIVASLAEEATVK
                     TISRSEVDEAIDRFFNEL"
     gene            complement(9404..10333)
                     /locus_tag="VQ543_001157"
     CDS             complement(9404..10333)
                     /locus_tag="VQ543_001157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006154193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HET2611885.1"
                     /translation="MEKIVITATAESIEQVEQLLEAGVDRIYVGEKDFGLRLPTTFSY
                     DQLREIAKLVHDAGKELLVAVNALMHQDMMDRIKPFLDFLEEIKTDYITIGDAGVFYV
                     VNRDGYSFKTIYDASTMVTSSRQINFWGQKAGASEAVLAREIPSAELFKMPEILEIPA
                     EVLVYGASVIHHSKRPLLQNYYNFTHIDDEKTHKRDLFLAEPSDPESHYSIFEDNHGT
                     HIFANNDLDLMIKLTELVEHGFTRWKLEGLYTPGQNFVEIAKLFIQARSLIQEGNFSH
                     DQAFLLDEEVRKLHPKNRFLDTGFYDYDPDMVK"
     gene            10473..10760
                     /locus_tag="VQ543_001158"
     CDS             10473..10760
                     /locus_tag="VQ543_001158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001145225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3270 domain-containing protein"
                     /protein_id="HET2611886.1"
                     /translation="MPVRKLQSYEVDYQEELNQQLPHYQAYTPEAQSDANLKEILFFI
                     NIAVFCICIAIFSFIFLALKLSTALAFAAAIGFSLLVLKVQRSIIKRKRRR"
     gene            complement(10794..12128)
                     /gene="ciaH"
                     /locus_tag="VQ543_001159"
     CDS             complement(10794..12128)
                     /gene="ciaH"
                     /locus_tag="VQ543_001159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000491790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     CiaH"
                     /protein_id="HET2611887.1"
                     /translation="MFSKLKKTWYADDFSYFIRNFGVFTLIFSTMTLIILQVMHSSLY
                     TSVDDKLHGLSENPQAVIQLAINRATEEIKDLENARADASKVEIKPNVSSNTEVILFD
                     KDFTQLLSGNRFLGLDKIKLEKKELGHIYQIQVFNSYGQEEIYRVILMETNISSVSTN
                     IKYAAVLINTSQLEQASQKHEQLIVVVMASFWILSLLASLYLARVSVRPLLESMQKQQ
                     SFVENASHELRTPLAVLQNRLETLFRKPEATIMDVSESIASSLEEVRNMRFLTTSLLN
                     LARRDDGIKPELAEVPTSFFNTTFTNYEMIASENNRVFRFENRIHRTIVTDQLLLKQL
                     MTILFDNAVKYTEEDGEIDFLISATDRNLYLLVSDNGIGISTEDKKKIFDRFYRVDKA
                     RTRQKGGFGLGLSLAKQIVDALKGTVTVKDNKPKGTIFEVKIAIQTPSKKKK"
     gene            complement(12118..12792)
                     /gene="ciaR"
                     /locus_tag="VQ543_001160"
     CDS             complement(12118..12792)
                     /gene="ciaR"
                     /locus_tag="VQ543_001160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator CiaR"
                     /protein_id="HET2611888.1"
                     /translation="MIKILLVEDDLGLSNSVFDFLDDFADVMQVFDGEEGLYEAESGV
                     YDLILLDLMLPEKNGFQVLKELREKGITTPVLIMTAKESLDDKGHGFELGADDYLTKP
                     FYLEELKMRIQALLKRSGKFNENTLTYGNIVVNLSTNTVKVEDTPVELLGKEFDLLVY
                     FLQNQNVILPKTQIFDRLWGFDSDTTISVVEVYVSKVRKKLKGTTFAENLQTLRSVGY
                     LLKDVQ"
     gene            complement(12901..15447)
                     /locus_tag="VQ543_001161"
     CDS             complement(12901..15447)
                     /locus_tag="VQ543_001161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001149089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M1 family metallopeptidase"
                     /protein_id="HET2611889.1"
                     /translation="MQAVEHFIKQFVPEHYDLFLDLSRETKTFSGKVTITGQAQSDRI
                     SLHQKDLEITSVEVAGQARPFTVDHDNEALHIELAEAGQVELVLAFSGKITDNMTGIY
                     PSYYTVDGVKKEVLSTQFESHFAREAFPCVDEPEAKATFDLSLRFDQAEGELALSNMP
                     EIDVENRKETGIWKFETTPRMSSYLLAFVAGDLQGVTAKTKNGTLVGVYSTKAHPLSN
                     LDFSLDIAVRSIEFYEDYYGVKYPIPQSLHIALPDFSAGAMENWGLVTYREVYLVVDE
                     NSTFASRQQVALVVAHELAHQWFGNLVTMKWWDDLWLNESFANMMEYVCVDTIEPSWN
                     IFEDFQTGGVPLALERDATDGVQSVHVEVKHPDEINTLFDGAIVYAKGSRLMHMLRRW
                     LGDADFAKGLHAYFEKHQYSNTIGSDLWDALGQASGRDVAAFMDSWLEQPGYPVLTVK
                     VENDVLKISQKQFFIGENEDKNRLWVVPLNSNWKGLPDTLETESIEIPGYAALLAENE
                     GALRLNTENTAHYITDYQGDLLEAVLAELETLDNTSKLQIVQERRLLAEAGHIAYADL
                     LPVLDKLAKEESYLVVSAVSQVISALERFIDEGTDAETAFKGLVAKLARHNYDRLGFE
                     AKDGESDEDELVRQLAVSMMIRSNDAEASQVASQIFATHKENLAGLPAAIRSQVLINE
                     MKHHETKDLLALYLDTYTHATDAVFKRQLAAALAYSTDADNIQNLITSWKDKFVVKPQ
                     DLSAWYYQFLAHQATQKTAWSWARENWAWIKAALGGDMSFDSFVILPAHVFKTQQRLA
                     EYKEFFEPQLSDLALSRNIGMGIKEIAARVDLISREKAAVEAVVLQYGNA"
     gene            complement(15571..16011)
                     /locus_tag="VQ543_001162"
     CDS             complement(15571..16011)
                     /locus_tag="VQ543_001162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ASCH domain-containing protein"
                     /protein_id="HET2611890.1"
                     /translation="MIPQEMWNKYKQINPLIGDEIDAWAFGVEPDLLADLVFKGEKTA
                     TASAYDLYVLEDEPLPQVGTFDVILDSQNQSVCIVEITKVSVELFNQVSAQHAFKEGE
                     GDKSLAYWRQVHEDFFTDCLGEVGLTFTPESKVVLEEFRKVYPL"
     gene            complement(15986..16855)
                     /locus_tag="VQ543_001163"
     CDS             complement(15986..16855)
                     /locus_tag="VQ543_001163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PEP-utilizing enzyme, TIM barrel domain protein"
                     /protein_id="HET2611891.1"
                     /translation="MRNQLALSGEKILEKIYPQLFHHVGMIRGEYLLRELNQNIILAS
                     CQQFVKDYLETICSLYSDEEVWYRFTELTNTEANCLVGTKEFFDEGHPLFGYRGTRRL
                     LACLDEFQAEAHVVTEVYQTNPNLSVIFPFVNDADQLKQAITVLRQYGFTGKVGTMIE
                     LPSAYFDLSSILETGISKIVVGMNDLTSFVFATMRNSQWHDLESPIMLDMLRDMQDKA
                     RKNKINFAVAGYLNTSFIQKMNQLGIKCIIHYSSIPEIFDLEIDHPDHLKHIKEESKK
                     LQRSTHDTARNVE"
     gene            complement(16897..17625)
                     /locus_tag="VQ543_001164"
     CDS             complement(16897..17625)
                     /locus_tag="VQ543_001164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET2611892.1"
                     /translation="MELFKTWKKNMVLYGLKSQIGTVYRNNDRTTSFYDVGNFLYLAG
                     ELDSRFWEDFVRKYGLDYKIIISENTNWQDFLHRKVGLNSFTRYSFKDKANFQVEFLN
                     NLVTHLEEGYNIVPIDNHIYNCFSTEEWSQDLQGDFESYQDFVLKGGFGFVILKNNEL
                     IAGISSGLVYRKAVEVEVATRPNEQGNGFAKKLGAAMILESLNRDMFPLWDAHNEASK
                     KVAEFLGYELSEPYEAFELEEILI"
     gene            complement(17633..18112)
                     /locus_tag="VQ543_001165"
     CDS             complement(17633..18112)
                     /locus_tag="VQ543_001165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000403355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HET2611893.1"
                     /translation="MEIKKHFGVYAVCLENGKLLCIEKTRGPYQHRYDLPGGSQQLGE
                     GLTETLTREVMEETGFTVRSYSNPRIYDVFVREELTNFMVDHVMALYDVEMNESAPQV
                     TTSEAVSDGANDSLGYIWMDIQEITEENASPLVLKVKSELLGFPELDKTSYMNWKVK"
     gene            complement(18123..18821)
                     /locus_tag="VQ543_001166"
     CDS             complement(18123..18821)
                     /locus_tag="VQ543_001166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-ACP reductase"
                     /protein_id="HET2611894.1"
                     /translation="MTKRVLITGVSSGIGLAQARLFLEKGYQVYGVDQGEKPLLEGDF
                     HFLQRDLTLDLEPIFDWCPQVDVLCNTAGVLDDYKPLLEQTAQDIQEIFEINYIIPVE
                     LTRYYLTQMLENKKGIIINMCSIASSLAGGGGHAYTSSKHALAGFTKQLALDYAEAGI
                     QVFGIAPGAVKTAMTAADFEPGGLADWVASETPIKRWIEPEEIAELSLFLASGKASAM
                     QGQILTIDGGWSLK"
     gene            complement(18814..19080)
                     /locus_tag="VQ543_001167"
     CDS             complement(18814..19080)
                     /locus_tag="VQ543_001167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2829 domain-containing protein"
                     /protein_id="HET2611895.1"
                     /translation="MKNVELKEKNMTFEEILPGLKAKRKYVRTGWGGAENYVQLFDTI
                     EQNGLALEMTPYFLINVSGEGEGFSMWSPTVCDVLATDWVEVHD"
     gene            complement(19146..20072)
                     /locus_tag="VQ543_001168"
     CDS             complement(19146..20072)
                     /locus_tag="VQ543_001168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001269463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase family oxidoreductase"
                     /protein_id="HET2611896.1"
                     /translation="MRYITLGQDDKELSEIVLGMMRIKDKSVKEVEELVETALSVGIN
                     AFDLADIYGRGRCEELLGLVLKNRPDLREKMWIQSKCGIRIEEFTYFDFSKDYIIKSV
                     DGILQRLKIDHLDSLLLHRPDALMESDQVAEAFNLLYKQGKVRDFGVSNQNPMMMELL
                     KKDVKQPLAVNQLQLSAAFTPGFESAFHVNMEDSQAAMRDGSIFEYCQLHDVVIQAWS
                     VLQFGYFKGNFVGNEKFQALNQVLDRLAIKYGVTSSTIAISWILRYPAKMQAVVGTTN
                     PKHLREVSRAANFSLTRKEWYEIYLAAGNNLP"
     gene            complement(20147..20962)
                     /locus_tag="VQ543_001169"
     CDS             complement(20147..20962)
                     /locus_tag="VQ543_001169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2611897.1"
                     /translation="MKKMKYYEETSALLHEFSEENQKYFEELWESFNLAGFLYDEDYL
                     REQIYLMMLDFSEAERDGMSAEDYLGKNPKKIMKEILKGAPRSSIKESLLTPILVLAV
                     LRYYQLLSDFSKGPLLTVNLLTFLGQLLIFLIGFGLVATILRRSLVQDSPKMKIGTYI
                     VVGTIVLLVVLGYVGMASFIQEGAFYIPAPWDSLSVFTISLVIGIWNWKEAVFRPFVS
                     MIIAHLVVGSLLRYYEWMGISNVFLTKVIPLAVLFIGIFVLFRGFKKIKWSEV"
     gene            complement(20966..21286)
                     /locus_tag="VQ543_001170"
     CDS             complement(20966..21286)
                     /locus_tag="VQ543_001170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000665424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HET2611898.1"
                     /translation="MKETQLLKGVLEGCVLDMIGQKERYGYELVQTLREAGFDTIVPG
                     TIYPLLQKLEKNQWIRGDMRPSPDGPDRKYFSLTKEGEERVSVFWQQWDDLSQKVEGI
                     KNGG"
     gene            complement(21583..21663)
                     /locus_tag="VQ543_001171"
                     /pseudo
     CDS             complement(21583..21663)
                     /locus_tag="VQ543_001171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(21707..23704)
                     /gene="metG"
                     /locus_tag="VQ543_001172"
     CDS             complement(21707..23704)
                     /gene="metG"
                     /locus_tag="VQ543_001172"
                     /EC_number="6.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine--tRNA ligase"
                     /protein_id="HET2611899.1"
                     /translation="MSEKNFYITTPIYYPSGKLHIGSAYTTIACDVLARYKRLMGYDV
                     FYLTGLDEHGQKIQQKAEEAGITPQAYVDGMAVGVKELWQLLDISYDKFIRTTDDYHE
                     KVVAQVFERLLAQDDIYLGEYSGWYSVSDEEFFTESQLAEVFRDEAGNVTGGIAPSGH
                     EVEWVSEESYFLRLSKYQDRLVEFFKAHPEFITPDGRLNEMLRNFIEPGLEDLAVSRT
                     TFTWGVPVPSNPKHVVYVWIDALLNYATALGYAQDEHGNFDKFWNGTVFHMVGKDILR
                     FHSIYWPILLMMLDVKLPDRLIAHGWFVMKDGKMSKSKGNVVYPEMLVERYGLDPLRY
                     YLMRNLPVGSDGTFTPEDYVGRINYELANDLGNLLNRTVSMINKYFDGQIPAYVEGVT
                     EFDHVLAEVAEQSIADFHTHMEAVDYPRALEAVWTLISRTNKYIDETAPWVLAKDEAL
                     RDQLASVMSHLAASIRVVAHLIEPFMMETSRAVLTQLGLEEVSSLENLSLADFPADVT
                     VVAKGTPIFPRLNMEEEIAYIKEQMEGNKPAVEKEWNPDEVELKLNKDEIKFEDFDKV
                     EIRVAEVKEVSKVEGSDKLLQFRLDAGDGEDRQILSGIAKYYPNEQELVGKKVQIVAN
                     LKPRKMMKKYVSQGMILSAEYDGKLTLLTVDPAVPNGSVIG"
     gene            complement(23828..25087)
                     /locus_tag="VQ543_001173"
     CDS             complement(23828..25087)
                     /locus_tag="VQ543_001173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET2611900.1"
                     /translation="MQNLKFAFSSIMAHKMRSLLTMIGIIIGVSSVVVIMALGDSLSR
                     QVNKDMTKSQKNISVFFSPKKSKDGSFTQKQSAFTVSGKEEEVPVEPPKPQESWVQEA
                     AKLKGVDSYYVTNSTNAILTYQDKKVENANLTGGNRTYMDAVKNEIIAGRSLREQDFK
                     EFASVILLDEELSISLFESPQEAINKVVEVNGFSYRVIGVYTSPEAKKSKIYGFGGLP
                     ITTNISLAANFNIDEIASIVFRVNDTSLTPTLGPELARKMTELAGLQQGEYQVADESV
                     VFAEIQQSFSFMTTIISSIAGISLFVGGTGVMNIMLVSVTERTREIGLRKALGATRAN
                     ILIQFLIESMILTLLGGLIGLTIASGLTALAGLLLQGLIEGIEVGVSIPVALFSLAVS
                     ASVGMIFGVLPANKASKLDPIEALRYE"
     gene            complement(25089..25790)
                     /locus_tag="VQ543_001174"
     CDS             complement(25089..25790)
                     /locus_tag="VQ543_001174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2611901.1"
                     /translation="MKQLISLKNIFRSYRNGDQELQVLKNINLEVNEGEFVAIMGPSG
                     SGKSTLMNTIGMLDTPTSGEYYLEGQEVAGLGEKQLAKVRNQQIGFVFQQFFLLSKLN
                     ALQNVELPLIYAGVSSSKRRKLAEEYLDKVELTERSHHLPSELSGGQKQRVAIARALV
                     NNPSIILADEPTGALDTKTGNQIMQLLVDLNKEGKTIIMVTHEPEIAAYAKRQIVIRD
                     GVISSDSAQLGKEEN"
     gene            complement(25774..26973)
                     /locus_tag="VQ543_001175"
     CDS             complement(25774..26973)
                     /locus_tag="VQ543_001175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter periplasmic adaptor
                     subunit"
                     /protein_id="HET2611902.1"
                     /translation="MKKKNGKAKKWQLYAAIGAASVVVLGAGGILLFRQPSQTAVKDE
                     PTHLVVAKEGSVASSVLLSGTVTAKNEQYVYFDASKGDLDEILVSVGDKVSEGQALVK
                     YSSSEAQAAYDSASRAVAKADRHINELNQARNEAASAQAPQLPAPVGGEDATVQSPTP
                     VAGNSVASIDAQLGDARDARADAAAQLSKAQSQLDATTVLSTLEGTVVEVNSNVSKSP
                     TGASQVMVHIVSNENLQVKGELSEYNLANLSVGQEVSFTSKVYPDKKWTGKLSYISDY
                     PKNNGEAASPAAGNNTGSKYPYTIDVTGEVGDLKQGFSVNIEVKSKTKAILIPVSSLV
                     MDDSKNYVWIVDEQQKAKKVEVSLGNADAENQEITSGLTNGAKVISNPTSSLEEGKEV
                     KADEATN"
     gene            27259..28605
                     /gene="gor"
                     /locus_tag="VQ543_001176"
     CDS             27259..28605
                     /gene="gor"
                     /locus_tag="VQ543_001176"
                     /EC_number="1.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-disulfide reductase"
                     /protein_id="HET2611903.1"
                     /translation="MREYDIIAIGGGSGGIATMNRAGEHGAKAAVIEEKKLGGTCVNV
                     GCVPKKIMWYGAQIAETFHQFGEDYGFKTTDLNFDFATLRRNREAYIDRARSSYDGSF
                     KRNGVDLIEGHAEFVDSHTVSVNGELIRAKHIVIATGAHPSIPNIPGAELGGSSDDVF
                     AWEELPESIAILGAGYIAVELAGVLHTFGVKTDLFVRRDRPLRGFDSYIVEGLVKEME
                     RTNLPLHTHKVPVKLEKTTDGITIHFEDGTSHTASQVIWATGRRPNVKGLQLEKAGVT
                     LNERGFIQVDEYQNTVVEGIYALGDVTGEKELTPVAIKAGRTLSERLFNGKTTAKMDY
                     STIPTVVFSHPAIGTVGLTEEQAIKEYGQDQIKVYKSSFASMYSACTRNRQESRFKLI
                     TAGSEEKVVGLHGIGYGVDEMIQGFAVAIKMGATKADFDATVAIHPTASEEFVTMR"
BASE COUNT         8571 a         6300 c         5114 g         8662 t
ORIGIN      
        1 ttttagtcta gtataaatag cgagaaatat ctatcctatc ttctagaatg tcttccaaac
       61 gagaaaactc tcgtaaacaa agaggtttta gaggcctatt taccgtggac taaagttgta
      121 caagaaaagt gcaaataaga aatctccaga ttaggaacta tccgtgagtt ctctagtctg
      181 gagatttttc aatagacttc gttattggac ggttaccaag ttacttcaaa gtacagattt
      241 gaagctgcag ataagactga cgaaatcact ttaatactaa atgaaaatca aaaagcaaac
      301 taagaagcta gcctcaggct gtacttgagt acggtaaggc gacgctgacg tgatttgaag
      361 agattttcga agagtataaa acactgtttt gaagtggtgg ataaatcggc tgggtaaaaa
      421 ctcaatctca ggagaaaatg aagtaaatct ccccacaact atagaaaaag atttgattct
      481 gctcctcaca caataaaatc tttttctttt attaaaaacg aatcgtttca cgtgttttct
      541 catatgaggt aacaaagcga ttggttacac caggctctgc cacttccaat gcttgagaaa
      601 tcttgtcaaa tgaagcgtga taatcaaatt ctttttcaaa aatatctaaa gcttcgttaa
      661 atgcttcttg aatgcgttca tcaaatgagc gatagcggtt agaatattgc aagagttgct
      721 ctgtcaaagt tgcatattgt acaatattat aagtttccgt ttctaaagct tccatatcat
      781 tcgttgcaat ttcaagaact cgggtaacag attcaatgtt aatcattttt tgttctaact
      841 caaccattaa atcctcggta ttattgcttg ccgtaaagaa taacttcaag aaagtttgtg
      901 gaatacctgg cagattgcgt ttttccatgt atcgcttgat agtatggaga cgattgacat
      961 aaacattggc cttttgacgt gcattaatat catctttctc aatttgtgtc aggcgctcac
     1021 taactgaaat ttgctcatct tcaatatctt ttagttgagt ttgtaaatcc tcaagatttt
     1081 cttcaagaac tgaataagct tgggttggtt cttcttgatt tgaagttacc tcaacaatag
     1141 ctgcctcaaa actctctaat tctgtctgaa tacgacgaac atggcttgca gctgtctcag
     1201 gaagtaaata ggtcttgttc aaacgtgcaa tatcttctcc caataaagta ttattctctt
     1261 tcatatgttg aaggtaagtt ggaagagttg caagtagatt ttccactact ttctgagcag
     1321 caatttctcg agtaaaaata tcatacaagg cattgatttc ctcttgtgcc tgtccattct
     1381 catattcggc attatccaat tccaactgac gaatattctc ttggtttttc ttgaatgctt
     1441 cataaagcaa gtggaaacgc gcttcaatat ccgtttcaac aaaatgataa ttagcatcaa
     1501 ttagtttacg ataaccggct tccaaatcct gtaattgatc tggcaattct gtagaaagcg
     1561 tcgtaaccaa ggctggaaca cgatccacaa tatgacttaa ggccaaaatg tgattttctg
     1621 tattatccaa aatcactgcg gcttccacag ggtcacccga tgaattcaag gttacaaatt
     1681 gtgaaaattc agattggata ttttctaatt gtttttcaat ttcatccaag gcttgaccat
     1741 actgttctga attttcagca actctatgct gaagttcctc aaataaatcc aaagcatgaa
     1801 gaacacgacc actattttta gattcttgct tctctaagtc tgccaaagca ttgcgaattg
     1861 ccgcaatatc ttcttcaatc aaagtaattt gactctcaat ttggtcaatt tgatgactgg
     1921 ccttgagaaa acgaaatgaa tggttataac cttctgcttc aaagagatta ttttcaatat
     1981 cggcaaaaga gttgagagat aaatcgaccc atttttgatt ccattcacgg aaagccactt
     2041 gactttgtcc aatcaagtgc atatttttta cagcttctac ttcatcattt actggaagat
     2101 tgtatagttc ttcttttctt tcttctagcg cctctaatct cccctcgttt cgcttacgta
     2161 gaaagattgc cactacataa gccagaacta aaatgactgc aattgcaacc attaaataaa
     2221 ttagttgtcc attagacata tcaaactcct tttttacttg aaacaatcgt aacgattata
     2281 tcatattttt tagaccaagg gaactacttc tccctatttt ttagacatca agtgtactat
     2341 agacagcatt ttcttcgata aactcacgac gaggctctac tcgatccccc atcaacatat
     2401 caaagatttt atctgcttct gcagcatcat ctacagaaac tctagccatc aagcgatgtt
     2461 cgggatccat ggttgtttcc cacagctgat gatcgtccat ttcacctagc cccttataac
     2521 gctgaatagt cggtttggta cgaccttcac tataacgggc taaagcttct tggagtttga
     2581 tttcttgatc tgcacccggc tggatatatt ctttaatctc gcttccaacc ttgacaccat
     2641 agattggtgg ttgggcaata taaacataac cagcttctag gattggtttc atataacgat
     2701 aaatcaaggt taaaagaagg gtacgaatat gggctccatc gacatcggca tcggtcatca
     2761 aaacgagttt ttggtaacgg gctttcgaaa catcaaattc tgcgccaaat cctgttccca
     2821 tggctgtgaa aagactacga atttcttcgt tagctagaat cttatccata cttgcttttt
     2881 caacgttcaa aatcttaccg cgaattggaa ggatagcctg aaactcacgg ttacgaccag
     2941 atttggctga tccaccagct gagtctcctt cgacgatgaa gagttctgtt tcagcagggt
     3001 tattagaaga acagtctgct agtttccctg gaaggttgga aatttccaaa ccagattttt
     3061 tacgtgtgac ttcacgcgca cgcttggcag ccacacgagc cttggcagct aaaatccctt
     3121 tttccacgat acgtttggca atctgtggat tttccatgag gaaatcggag aaggcttcac
     3181 tgaagaggcg attggtaatc ttgaccactt cgctatttcc caatttggtc ttggtttgtc
     3241 cttcaaactg tggatttggg tgtttaactg agataactgc agttaatcct tcgcgaacat
     3301 cttcccctgt taaattatct tcattgtctt tcagtaactt attcttacga gcataatcat
     3361 tgataacacg agtcagtgcc gtacggaaac cttgttcatg cgttccacct tcatgggtat
     3421 gaatattatt ggcgaaactc atgacatttt catggtaacc tgttgtgtac tgcatggcta
     3481 cctcaactgt gatatcatcc atctcaccgt ctgtatagat tggtgtatca aagattacat
     3541 ccttgttctc gttgatatat tcaacgtaac tagcaatccc accttcataa tgataatgct
     3601 tggtttgttc caaaccttgg cgcttatcag tgatagaaat ttgaagaccg cgatttagaa
     3661 aggccaactc ttgaatccgt ttatttaatt tatcaaaatc aaaggttgtt gtttcagtaa
     3721 agatttttgg gtccggtatg aagtgaaccg ttgttccagt tctatctgta tccccaacca
     3781 cctcaaggtc tgcaacaaca tgaccacgac ggtattcttg gtaatgaatc ttaccgtttt
     3841 tatggacatg aacgtctaat tgagtggaaa gggcattaac tactgacgac cccaccccgt
     3901 gaagaccacc tgaaaccttg tatccaccac cgccgaactt tcctccagca tgaaggactg
     3961 taaagacggt ctcaacagca ggacggcctg ttttttcctg aatatcgact gggataccac
     4021 gcccatcatc cacaacagta atcgaatcat ctggctcaat aaaaacttga atatggctgg
     4081 caaatcctgc caaggcctcg tcaattgagt tatcaacaat ttcccagact agatggtgaa
     4141 gaccttcttt tgaggttgat ccaatgtaca tccctggacg catacgaaca gcctctaagc
     4201 cctctaaaac ttgaatttga ctggcatcat aatcctgtgc ctgcagattt ttgatttctt
     4261 ctgtcatctt attccttttt cttatatgtc taatacttgt cttaaattca cgatactggt
     4321 aaacaagtgg gtatcaagtc ctgcagcttg acctgcttcg atatcaatcg gccgatcacc
     4381 aatgacaaga ccagagctaa tctgatactt ttctcttaaa taaagcatgg attcgggatt
     4441 tggctttctc ttaaagcctg agctagaagt caccacttct gtaaaataag ctgctataga
     4501 ggttttttct aaaatttcca aaacctgatc atttcgatga gagaccaaaa aatgacggcc
     4561 accttgattt aaaatgtctt ccaataggtc agaaactcct tcaaataaaa tcgggtgttc
     4621 aagctctctg gcttcatttt ccttgtactt ttctaaaaaa ttctctaaat tgggagcgaa
     4681 tgtctcaatc gcaaaaggag tagaaacctt taaagcttga tagacactgt catggtcttg
     4741 tgtgatacca tacagtgcca atgtttcaac aaatgcagct gttgaagttt cataattatc
     4801 cagtaaagtt ccacctaaat cccagatgta atcgtgatat ttcataccct tcattatagc
     4861 atttttttat gaaaaaagcg atgatttccc tgagttttcc acataaaaaa cgagagaata
     4921 actcccgttt tactgatttt taccaaagac atctcgatag agcattcctg ttcgtaaact
     4981 ctctgcgtcc cctcctagtt gctccaccaa ctcgtaggca aaggcaaggg ctgttgaagg
     5041 accccgactg gttgtcaact gaccatctac cactactgtt tccttgacgt agtgaccatc
     5101 aaggatttgc tcttgaacgc cgtcataaca agtgtatcgc ttatttttca atatctctgc
     5161 ttgattgagg gcaattggtg ccgcacaaat ggctgctagt ttcttccctt cttgctcgaa
     5221 gctttgcaat tcttgaatca aggtctgatt atcacgtaaa tgtgcagaac caggcatacc
     5281 tccaggaaga acaatcatat catagtctga taaatctcca tcaaagacat gatctgctct
     5341 tacttggatt gcatgcgaac ccgttacttg ctcttcaaaa ccaaccatat cacatgtgat
     5401 attggctcga cgcaagacat ctacaactgt caaggcttca atttcttcaa agccctgagc
     5461 taacataact gctactttta ccatgatttt ctccttattt aatttgtttt aatacaacct
     5521 ttttccgttt gaatgggact tttccgctct tttcttcagc tagattagtc tggtaactca
     5581 tcgataaaag caaaccaaca ccaatcagat tactgataat agctgatccc ccttgcgaaa
     5641 tgaaaggcaa gggaatcccc gtcaaaggaa gtagtccagt cacagcaccg atattctcaa
     5701 agatgtggaa gagcaacatc ataatcaaac ctgtggaaat ataagtgtag aactggttat
     5761 ttgatttaag agtaatcttc aacatacggt aaatcaacat gagatagagg gcaataacca
     5821 ggacagagcc aataaagcca aaatcttctg caataaccgt aaaaatcata tctgactctc
     5881 gaactgggat aagcagattc gaagcattaa atccctgacc aaataagcca ccactcccaa
     5941 tggcaatctg cccttgagcc tgctggtaag tcgttgtttg ggcaaactca aagggattga
     6001 gccaagccaa aatccgattg atttggtagg tcggcattcc aatctggtga agaaaagctc
     6061 gtccgtcctt gctaataaag atagctaaga aaccagcaac tcctgttaca gcagtcacaa
     6121 atactgggat aataattttc caagaaaccc ctgataataa aacgattcct gagaaaatgg
     6181 ctacaaaaac caaagccgtc cccaagtcac tttgaagtgc taaaagaact aggactggaa
     6241 tggtaaagag aatcatccag aaaattaaca aaaagtccag cgaaaccgtg cgtctccatt
     6301 ccttatgttt ctttgtaaat tggacaatga cacgagccaa catgaggata taggatatct
     6361 tcataaattc tgacggttga aatagggtaa ttccatttat tgatacccag tttttggcac
     6421 ccgttgatgc aactaagctt ggattataaa atacaatcgg caagatcata agtcccaagc
     6481 ctaaaatata tagaaagggg gtcaccttcc aaagaaattc tgtattaaag agcatgacca
     6541 caaaaccaat cacaagcccc aaggcaatcc aggcgacctg ctgccctaaa atgggcagaa
     6601 tattattggg ataatcatga ctaacggcta tatagatagc caccacaccg atgaccagta
     6661 gaaaaaatac tggcaagagc aaactataat cgactctaga gtcgagagaa cgtttcatat
     6721 atactaacct tatactttca tacaatacta tttatcaaag ttcattaaaa aatctatcaa
     6781 tagcctcgtc aacttcggat cgagagatgg ttttaacagt cgcttcttct gctagagatg
     6841 ctactatttg tttgccgtat cgttttccga tgattctcct atccaaaata agagttaagg
     6901 aacgttggta ttcacgtctc atacttcttc ccaaagcctg ttttaaacga ataatggcca
     6961 ttggcaattg ataatcataa aaggcatttt tcccttcttg attcagttct tgattaatct
     7021 ttttcgtcaa gggttcttga ggattttgga aaggaagcct cggtacaact tgaatcacaa
     7081 aaggatggct tgaaaaatca actccctccc agaaacttgc tgcaccaagc aagatttgtt
     7141 gttcaccttt ttcaaagcgt ttctttagct gatgaacatc cccattttta tactgggcca
     7201 agtggctaac tgtaagtaaa tccgatactg ctagaagcat gtctttagcg gtaaagagaa
     7261 ccaaaatcgg ttgctggaaa gcttgaattt ccactagtaa agcagctacc tctctggcat
     7321 agacttctaa ggaggtttct gttaccagag ggaaatcttt gaccataacc acttcttgtt
     7381 cctgttttcc ccgagattca atcttgacaa atttggcttc aggatagcct aaaaggtctg
     7441 ccaaagaaac cctctgacta atctcaagag tagccgatac tcccatggct tggcaactct
     7501 caggaagtaa agaggacaga agagtacggc ctgattttgt agaagaaatc tgaattttct
     7561 tttgactcgt ttcagttact tcaagccagt aatcaccttc agctgtaaaa tagcgaacca
     7621 gctcatcaaa gccttctact tctaattctg aaaaatactg atggagattg tccagagaat
     7681 ctaagatatt tttcctagat ttaccagact gaaattgttc tatcaagtag agacactcaa
     7741 agcgaatact ttctagtatc cgttgttgaa ccctgttttc ttctcctact aaagccttat
     7801 caattaaatc gataatagat tgtatatcgt aggtctcttg aagcagattt tctagagcta
     7861 acaaaatctt ttggacttca tcaataatca gtaaacggtc actgacaaat tcaggattat
     7921 cttcaagtct ggtcacgaga taggcatgat tagtcactaa aagcttgcaa gtctctgccc
     7981 tttcttgact acgtttccaa aaatcttccg tcacaaataa gctctgggat gataaattcc
     8041 catcatgacg aaggtctgct agaaaatgtt ggtaacgata gagttgcccg atttcatcca
     8101 aatctcctgt ctctgtctca gtaagccaga ccaagacttg cattttaaag cgtctaaata
     8161 agcgattttc atcattttcc tgcaaggaat gataaaaggc atccaacttc agataatttt
     8221 gtggtccctt taagctatga atatctgtat ggaacacttc cttgaggcgt ttaccttctt
     8281 cttccatgat ttgattttga agaatctttg tcggaacact aagaacaatt tgtcgctctt
     8341 tggattgaga taaagcgggt aagagatagc cataggtttt cccaatccct gtcggcgctt
     8401 gaatcagaga gacaggttca tctttcaata gcaagccaac ctctttagca aaactttctt
     8461 gttcctccct cacttcaagg ttcaacagag aaatattttt agaaaagtct tgagatagtt
     8521 ttcgtggctc cagagaagct gccgttttct taaaatacag accttgaact tggaccaagt
     8581 ctggagaact caggatagat tggttgcgat aagtttcctc aataaccagg taggactcat
     8641 ataggagagc gtcagccatt tccagcaagc gttccaagag acctttagga agctgagtca
     8701 tcttttcccg taaaaaaaga agtaattctg ctgtagcttg ggcatctgaa agggctgtgt
     8761 gtgcgtgttt aagaggaatt cctaattctc gacacaaaat cggcaagcta tatttttcca
     8821 gttcagggaa aaagacctgg gccaattcga ccgtatcaac acgagggttt cttagctcat
     8881 agccttcaaa aaataaattt tccgccaaga gattagcatc aaactgaaca ttatgggcta
     8941 caaaaatccc atcctccacc aagtcaaata tttttctggc aacttgcgaa aaatcaggtg
     9001 cttgcgccag acgttggtct gtcaatcctg tcagttcttt gatatgagca tccaagggtt
     9061 catgtggatt gacatccgtc gtatagtgat cgacgatttc tccgtcctca atcacgacaa
     9121 ttcccacttg gataatttta gccttactac ctgtgctagt tgcctctaaa tccaccacaa
     9181 catagcgatt accaatcgtt ttcattataa aaaattatac caaaaaaagg gccatttggc
     9241 acctgcaaac ataggataat tttcaaactc aagaacacta cttttcttaa aaatcccatc
     9301 gaatagagca ttctagcctg ctgatttttt aaaatagtga agaaatacga aaaattgaga
     9361 gaagaaatgt tttcatcttc cttctctcaa cgaatcatgt attttattta accatgtcag
     9421 gatcgtagtc ataaaatcct gtatcaagga aacggttttt agggtgaagt ttacgaactt
     9481 cttcatccag caagaaggct tggtcatggc taaagttgcc ctcttgaatc aagctacgcg
     9541 cttggataaa gagttttgca atctcaacaa agttctgacc aggagtgtag agcccttcta
     9601 gtttccagcg agtaaagcca tgctccacca attctgttaa tttgatcatc aaatcaaggt
     9661 cattgttggc aaagatatgg gtcccatgat tatcttcaaa aatggaatag tggctctctg
     9721 gatcacttgg ctcagccaag aagaggtcac gtttatgcgt cttttcatca tcgatatgtg
     9781 taaagttata gtagttttgc aagagtggac gtttagaatg atggatgacg ctagcaccgt
     9841 aaaccaaaac ttcagcagga atttccaaaa tctctggcat tttgaaaagt tcagctgatg
     9901 gaatttcacg cgccaaaaca gcctcagatg cgccagcctt ttgtccccag aagttaatct
     9961 gacgactgct agttaccatg gttgaagcat cgtagatggt cttaaatgaa taaccatcgc
    10021 ggttaactac gtaaaagacg cctgcatccc caatcgtaat atagtctgtc ttgatttctt
    10081 ccaagaagtc taagaaaggc ttgatacggt ccatcatatc ttggtgcatg agagcattga
    10141 ccgcaacgag caattcctta ccagcatcat gaaccaactt agcgatttca cgtaattggt
    10201 cataactaaa ggtcgttggc agacgaaggc caaaatcttt ctcaccgaca tagatacggt
    10261 ctacgccagc ttcgagtagt tgttcaactt gttcaatact ttcagcagtt gctgtaatga
    10321 caatcttttc cataagaaaa attataccac atttctccaa aatcatccat gctttgaaaa
    10381 tgaaaaggga ctttattctt tttgtaacct ttctgtaata attctctgcc gaaaaaatga
    10441 taaaataggt atgtactgtt aaggagagaa ttatgcccgt aagaaaatta caatcctatg
    10501 aggtagacta tcaagaagaa ttaaaccagc agcttcctca ttaccaagct tatacacctg
    10561 aagcgcaatc tgatgccaat ctcaaggaaa tcctattttt tattaatatc gctgtttttt
    10621 gtatctgtat tgctatcttt agttttatct ttttagcatt aaaattatca actgctcttg
    10681 cctttgccgc agcaatcgga ttcagcttac ttgttttaaa agttcaacgg tctattatca
    10741 aacgaaaacg tagaagataa atccaaaata tcgccccagt tggagcgata tttttatttt
    10801 ttctttttag atggtgtctg aatggcaatc ttcacttcaa agattgttcc cttgggttta
    10861 ttatctttga cagtaacagt tccttttaga gcatctacaa tttgcttggc tagggataat
    10921 cctaaaccaa aaccaccttt ttgccgagtt ctagccttgt ctactcgata aaaacggtca
    10981 aaaattttct ttttatcttc tgtcgaaata ccgattccat tatcagaaac aagtaaataa
    11041 agattgcgat cggtcgccga gataagaaaa tcaatttcac catcctcctc agtatacttg
    11101 acggcattat cgaaaagaat ggtcatcagt tgtttcagaa gaagctgatc tgtgacaatt
    11161 gttcgatgga tacgattttc aaaacggaag acacgattat tttccgaagc aatcatctcg
    11221 tagtttgtga aagttgtatt aaaaaagcta gttggaactt ctgcaagctc cggcttaatc
    11281 ccatcatctc tccgagctaa gttcagcaag cttgtcgtta aaaaacgcat atttcggact
    11341 tcttccaaac tcgatgcaat gctttcgctc acatccataa tggtagcttc tggcttacga
    11401 aaaagggtct ctaagcgatt ttgcaaaact gcgagtggag ttcgtaactc atgactggca
    11461 ttttccacaa aagactgttg cttctgcata ctctcaagca ggggcctaac actgacccta
    11521 gctagataga gactggcaag taaagacaaa atccagaaac tagccatcac gaccacaatc
    11581 aattgctcat gcttttgact agcctgttcc aactgactgg tattaatcaa gacagcagca
    11641 tacttgatat tggttgaaac cgaactaata ttggtctcca tcaaaatcac acgatagatt
    11701 tcttcctgcc catagctatt aaaaacctga atctggtaga tatgtcctag ttctttcttt
    11761 tctaacttaa tcttatccaa gcccaaaaat cgatttccag aaagaagttg agtaaagtct
    11821 ttatcaaaga gaatgacttc cgtattggaa ctgacattag gttttatttc tactttacta
    11881 gcgtccgccc tagcattttc taaatcttta atctcttctg ttgccctatt tatagccagc
    11941 tgaataactg cttgaggatt ttcactcagt ccatgaagct tatcgtccac cgaagtataa
    12001 agactcgaat gcatgacttg taaaataatc agagtcattg tagaaaaaat cagggtgaag
    12061 acaccgaagt tgcggataaa ataactaaag tcatccgcat accatgtttt tttaagttta
    12121 ctgaacatct tttaaaagat acccaacact acgcaaagtt tgcaaattct ctgcaaaagt
    12181 ggttcccttt aatttcttac ggacttttga aacatagact tcgacaaccg aaatcgttgt
    12241 atcactatca aatccccata gacggtcaaa aatctgcgtc ttaggcaaaa tcacattttg
    12301 attttgaagg aaataaacta gtaaatcgaa ctctttcccc agcaattcga caggagtatc
    12361 ttcaacttta acggtattgg ttgataaatt aaccacgata ttcccataag tcaaggtgtt
    12421 ttcattaaac ttccctgaac gtttgagaag ggcctgaatc cgcattttaa gttcttctag
    12481 gtagaaaggt ttggtcagat aatcatccgc tcccagttca aatccatgtc ccttgtcatc
    12541 caaactttcc ttggcagtca taatcagaac tggtgtcgta attccctttt cacgcaattc
    12601 ttttaagact tggaaaccat ttttttctgg caacatcaaa tccagcaaaa tcaagtcata
    12661 gacaccactc tcagcttcgt agagaccttc ttctccatca aatacctgca taacatccgc
    12721 aaaatcgtct aaaaagtcaa atactgaatt tgacagacct aggtcatcct caaccaataa
    12781 gatttttatc atgagaaact cctccttatt aaaactatta taccaaattt gccttaaaaa
    12841 aaactcaact ctctgcattt tacatgagat agctgagttt tctttttatt ttaggcttat
    12901 ttatgcattt ccgtattgaa gaacaactgc ttcgactgca gctttttcac ggctaatcaa
    12961 gtcaacacgc gctgcaattt ccttgattcc cataccgatg ttacggctaa gagcaaggtc
    13021 agaaagttgc ggctcaaaga actccttgta ttccgccaag cgttgctgag tcttaaatac
    13081 atgagcagga aggataacaa agctatcaaa gctcatatct cctccaaggg ctgccttaat
    13141 ccaagcccag ttttcacgcg cccaagacca agctgttttc tgagttgctt gatgagctag
    13201 gaattggtaa taccaagcag acaagtcctg tggtttgacc acaaatttgt ccttccaaga
    13261 agtaatcaag ttttggatat tatccgcatc tgtactgtat gcaagagctg ctgccaactg
    13321 gcgtttaaag acagcatctg ttgcgtgagt ataagtatca agataaagtg ctaacaagtc
    13381 tttagtctca tgatgtttca tctcattaat cagaacttgt gaacgaatag ctgctgggag
    13441 tcctgcaaga ttctccttgt gtgttgcgaa gatttggcta gcgacttgac tagcttctgc
    13501 atcatttgag cgaatcatca tcgaaacagc cagctgacga accaattcat cctcatctga
    13561 ttctccgtct ttagcttcaa aaccaagacg gtcatagtta tgacgagcca atttagcaac
    13621 cagtcctttg aaggctgttt cagcatccgt tccttcatca ataaagcgct caagggctga
    13681 aatcacttga gaaacagctg aaaccaccag ataagactct tccttagcaa gtttatcaag
    13741 aactggaagc aagtctgcat aagcaatgtg ccctgcctca gccaacaaac gacgttcttg
    13801 aacaatttgc agtttgcttg tgttatcaag tgtctctagc tcagcaagaa cagcttctaa
    13861 caagtctcct tgatagtcgg taatatagtg ggcagtattt tcagtgttga gacgaagagc
    13921 tccttcattt tcagcaagaa gagctgcgta gccagggatt tcgatacttt cagtttcgag
    13981 tgtatcaggc aagcctttcc agttgctatt gaggggcacc acccagagac ggttcttgtc
    14041 ttcgttctca ccgatgaaga attgtttttg tgaaatcttc aagacatcat tttcaacttt
    14101 aacagtaaga actgggtaac caggctgttc caaccaagaa tccatgaagg ctgcgacatc
    14161 acgtcctgac gcttgaccaa gggcatccca aaggtcacta ccaatggtgt tgctgtattg
    14221 gtgtttttca aagtaggcgt gcaaaccttt agcaaaatca gcatctccta gccaacggcg
    14281 aagcatgtgc atgagacggc ttcctttggc atagacgata gcgccgtcaa agagtgtatt
    14341 gatttcatct ggatgtttaa cttcgacgtg gacagactga acgccatcag tagcgtcacg
    14401 ttcaagagca agaggtactc cacctgtttg gaaatcttca aagatattcc agcttggttc
    14461 gatggtatcc acacagacgt attccatcat attagcgaaa ctttcattga gccaaaggtc
    14521 atcccaccat ttcatagtca cgaggttccc aaaccattgg tgagccaatt catgggccac
    14581 aacaagggca acttgttgac ggctagcaaa tgtagagttc tcatcgacaa ccaagtaaac
    14641 ttcacggtag gtcacaagac cccagttttc catagcacca gctgagaagt caggaagggc
    14701 gatgtggaga gattgaggaa ttgggtactt aactccatag taatcttcgt aaaactcgat
    14761 agagcgaaca gcgatatcca gtgagaaatc aagatttgaa agtggatgtg ctttggttga
    14821 gtagacacct accagggtac catttttagt tttagcggtc accccttgca aatcaccagc
    14881 aacaaaggcc aacaagtaag aagacatgcg aggtgttgtc tcaaacttcc agatacctgt
    14941 ttccttacgg ttttcaacat cgatttctgg catgtttgac aaggccaatt caccttctgc
    15001 ttggtcaaag cgaagagaga ggtcaaaagt tgctttggct tcaggctcat ccacacatgg
    15061 gaaagcttcg cgcgcaaaat ggctctcgaa ctgagtagac aagacctcct tcttgactcc
    15121 atcaactgta taataagaag ggtaaatccc tgtcatgttg tctgtaattt taccagaaaa
    15181 ggcaagaacc aattcaactt gaccagcctc agccaattcg atatgaaggg cttcattgtc
    15241 atggtcaact gtaaatggac gagcttgacc tgcaacttct acagaggtga tttccaagtc
    15301 tttttggtgg agggagatgc ggtcactctg tgcttgacca gtgatggtca ctttcccaga
    15361 aaaagtcttg gtctcacgac tcaaatctaa aaataaatca taatgttcag gaacaaattg
    15421 cttaataaaa tgttcaactg cttgcatagt tttctcctat tctaagttta agagctactg
    15481 ctcttcttca aacaaactta ttatatcata ttttgcttga gaaaaaagga ttggacagcg
    15541 atttccaaaa ctttcttcct tctaaatagt ctacagtggg tagaccttgc gaaattcttc
    15601 taaaacaacc ttgctttcag gtgtaaaagt cagccctact tcacccaaac agtctgtgaa
    15661 aaagtcctca tgaacctggc gccaataggc aagtgatttg tctccctcac cttccttaaa
    15721 ggcatgttgc gcagaaactt gattgaagag ttcaacagaa acctttgtaa tttcgacaat
    15781 gcagacagac tgattttgac tatctaaaat gacatcgaag gtccctactt ggggaagtgg
    15841 ttcgtcttct agtacataga ggtcataggc tgatgctgtt gctgtctttt ctcctttaaa
    15901 caccaaatcc gctaaaaggt ctggttcaac tccaaaagcc caagcatcga tttcatctcc
    15961 gatcaaagga ttgatttgct tgtatttatt ccacatttct tgcggtatca tgggtactcc
    16021 tttgtaattt tttactttct tcttttatgt gtttaagatg atctggatgg tcaatctcta
    16081 aatcaaaaat ctctggaata gaactgtagt ggataatgca cttgataccc aactgattca
    16141 ttttttgtat gaaagaagta ttcagatagc ctgctacagc aaaattaatc ttgttctttc
    16201 ttgctttatc ctgcatatct cttagcatat ctaacattat tggactttcc agatcatgcc
    16261 attgactgtt tctcatagtc gcaaaaacaa aggaagtcaa atcattcatt ccaactacaa
    16321 tctttgaaat gcccgtttcc agtatactag ataagtcaaa atacgctgac ggtaattcaa
    16381 tcatcgttcc gactttccca gtaaagccat actgacgcaa tactgtaata gcttgtttta
    16441 attggtcggc atcattgaca aaaggaaaga taacagatag attggggttg gtttgataaa
    16501 cttctgtaac gacatgtgct tcagcctgaa attcatccaa acacgccagt aaacgcctgg
    16561 ttcctctata gccaaacaag ggatgccctt cgtcaaaaaa ctctttagtc cccactaaac
    16621 aattggcttc tgtattcgtt aattcagtaa aacgatacca aacttcttca tctgagtaca
    16681 gggagcagat agtctctaga taatctttta caaattgctg acaacttgct aatatgatgt
    16741 tttgattaag ctctctcaac aaatattccc cacgaatcat gccgacgtgg tgaaatagtt
    16801 gaggataaat tttttcaaga attttttcgc cactaagggc aagttgattt ctcatagcca
    16861 ttcacctcgt cttaaaagat acaatatcat atataattat atcaaaattt cctctagttc
    16921 aaaagcttca taaggttcag ataactcata tcctaaaaat tctgctactt ttttggaagc
    16981 ctcattatga gcatcccaaa gtggaaacat atctctattt aaactctcta gaatcattgc
    17041 agcaccaagc tttttagcaa atccatttcc ttgttcgttt ggtctagttg caacttccac
    17101 ttcaactgct ttacggtaaa ctaaccctga ggaaatccca gcaatcagtt cattattttt
    17161 aagaatcaca aagccaaatc caccttttaa aacaaaatcc tgataggact caaaatcccc
    17221 ctgtaaatcc tgtgaccatt cttccgtaga aaagcagtta taaatatgat tatcaatagg
    17281 cacaatattg taaccttcct ctaaatgagt aactagatta tttaaaaatt caacttgaaa
    17341 atttgcctta tctttaaaag aatagcgagt aaaagaattt agccccactt ttcgatgcag
    17401 aaaatcttgc caattagtat tttctgaaat aataatctta taatctaaac catattttct
    17461 aacaaaatct tcccaaaatc tggaatccaa ctcccctgct aggtatagaa aattcccaac
    17521 atcataaaag cttgttgtcc tatcattgtt tcggtagaca gttccaattt gagatttaag
    17581 accatagaga accatatttt tcttccatgt tttaaatagt tccattatcc ctctacttca
    17641 ccttccaatt catgtaagaa gtcttgtcca gttctggaaa tcctaataat tcagacttaa
    17701 ccttcaagac taatggcgat gcattttctt ctgtaatctc ttgaatatcc atccaaatat
    17761 atccaagtga atcattcgca ccatcagaca cagcttccga agtcgtaact tgaggtgcac
    17821 tctcattcat ttcaacatca tacaaggcca tgacatggtc aaccataaaa tttgttaact
    17881 cttctctgac gaaaacatcg tagattcgag gattagagta gcttctaaca gtaaatcccg
    17941 tctcttccat aacttctcta gtcagcgttt ccgtcagtcc ttcaccaagt tgctgactgc
    18001 ctccaggtag atcataccga tgttgataag ggcctctcgt tttttcaatg cagagtaact
    18061 tcccattttc taagcaaaca gcgtagactc caaagtgttt tttgatttcc atccaactcc
    18121 tcctacttca aagaccagcc accatctatt gtcaagattt gtccttgcat ggcgctcgct
    18181 tttccacttg ctaaaaaaag actaagctct gctatttcct ctggctcaat ccagcgcttg
    18241 attggagttt cactagccac ccagtcagcc aaaccacctg gttcaaaatc cgcagcggtc
    18301 atagctgtct tgactgctcc tggagcgata ccaaagacct gaatcccagc ttcagcatag
    18361 tctagagcca actgcttggt gaagccagcc aaggcatgct tggatgaagt ataggcgtga
    18421 ccacctccac ctgctaggct agaagcaatg gaacacatat tgatgatgat tcccttttta
    18481 ttttccagca tttgtgtcaa ataataccga gtcaactcta ctggaataat gtagttgatt
    18541 tcaaaaatct cttgaatgtc ctgcgccgtt tgttccaaca gtggtttgta atcatccaaa
    18601 actccagcag tattacacaa aacatccacc tgagggcacc agtcaaaaat aggttccaag
    18661 tccaaggtca aatctctctg taaaaagtga aaatcaccct ctaagagtgg cttttcacct
    18721 tggtcaactc cataaacttg atagcccttc tctaaaaaga ggcgagcttg agccaatccg
    18781 atccctgaac tcactcctgt aatgagtaca cgtttagtca tgcacttcta cccaatccgt
    18841 tgccaaaaca tcacaaactg tcgggctcca catggaaaaa ccttctcctt cgccagaaac
    18901 gttgattagg aaataaggtg tcatttcaag tgcaagccca ttttgctcga tggtatcaaa
    18961 gagttggaca tagttttccg cacctcccca accagttcgt acatattttc tcttagcctt
    19021 taacccaggc aggatctctt caaatgtcat gtttttctcc tttaattcta cattcttcat
    19081 ttaattatag caaaaaaccg ctttatacgg ctttttgaat gtgagttatt caaacctgct
    19141 actacttacg gcaaattatt ccctgcagca agataaattt cataccattc ttttcttgtt
    19201 aagctaaagt ttgccgctcg gctaacttct ctcaagtgct taggatttgt tgtacctacg
    19261 actgcctgca tttttgctgg ataacgcaat atccaagaaa tggcaatagt tgaagaggtt
    19321 actccatatt taatagctaa acgatcaagt acttgattta aagcttgaaa tttctcattt
    19381 ccaacaaaat tccctttaaa atacccgaat tgtaagacag accatgcttg aatgaccaca
    19441 tcgtgtaatt ggcaatattc aaaaatgctg ccatctcgca tagctgcttg actatcttcc
    19501 atattaacat gaaaagctga ttcaaatcct ggagtaaaag ccgcactcaa ttgtagctga
    19561 ttaacagcta acggctgctt gacatctttt ttaagcaact ccatcatcat aggattttga
    19621 ttagaaactc caaaatctcg aactttacct tgtttataaa ggagattaaa ggcttctgct
    19681 acttggtcag attccatcaa agcatctggt cgatgaagga gcaagctatc tagatgatca
    19741 atcttcaatc tttgcaaaat accgtctact gattttataa tatagtcctt agaaaaatca
    19801 aaataggtaa attcttcaat gcgaatgcca catttggact gaatccacat cttttctctt
    19861 aaatctggac gattttttag gacaagacct aacagttctt cacaacgacc acgaccataa
    19921 atatcagcca agtcgaaggc attgattcca acagaaagtg ctgtttctac aagctcttca
    19981 acttctttta cagacttatc ttttattctc atcattccga gaacaatttc tgataattct
    20041 ttgtcatctt gaccaagagt tatgtatctc atcaaatttt tctcctttaa tttctaacat
    20101 tcttcccttc attataacaa aaaaccgctt tgcaacggct ttttgactat acttcactcc
    20161 attttatctt cttaaaccca cggaacaaga caaagattcc aataaagagg acagctaaag
    20221 gaataacttt tgtaaggaaa acatttgaaa ttcccatcca ctcataataa cggagcagag
    20281 aacccaccac aagatgggca ataatcatac tgacaaatgg acgaaagacc gcttctttcc
    20341 aattccaaat accgataact agcgaaatcg taaagacaga caaactatcc cagggagccg
    20401 gaatataaaa ggctccttct tgtatgaagc ttgccattcc tacatatcct aaaacaacta
    20461 gaagaactat agtcccaaca acaatgtaag tgccaatttt cattttagga gaatcttgga
    20521 ctaaacttct tcgtaaaatt gtggccacaa gtccaaatcc aatcagaaaa ataagaagtt
    20581 gccctaaaaa tgtgagcaaa ttgactgtta agagaggacc tttagaaaaa tcacttagta
    20641 gttgataata acgtaataca gccaggacaa gaattggcgt caaaagggac tctttgatag
    20701 aactgcgagg tgctcccttg agaatctctt tcattatttt tttaggattc ttacctagat
    20761 aatcctctgc actcatgcca tctcgttctg cttctgagaa atctagcatc atcaaataga
    20821 tctgctctct gagatagtct tcatcataga gaaatccagc aagattaaaa ctttcccaca
    20881 actcctcaaa atacttttga ttctcctcag aaaactcatg tagcaaagcg cttgtttctt
    20941 cgtaatactt cattttcttc atggtttaac ccccattctt aatcccttct actttttgac
    21001 tcaaatcgtc ccattgctgc caaaagactg agacacgctc ttctccttct ttcgttaatg
    21061 aaaaatactt ccgatctgga ccatctggcg acgggcgcat gtcgcctctt atccattgat
    21121 ttttttctaa cttttgcaac aaaggataaa tagttcctgg aacgatagta tcaaatccag
    21181 cctctcgcaa agtctgaacc aactcataac cataccgctc tttttgacca atcatatcca
    21241 agacacaacc ttcaagaaca ccttttaata gctgagtttc tttcatcact tctcccttct
    21301 aatctatttt gtaataccta ctagtaactt cacctatagt atattacttc tacactagtt
    21361 tgtaaagcat aatagttaat actcttcgaa aatctcttca aaccacgtca gcgtcgccct
    21421 accgtatgta tggttactga cttcgtcagt ttcatctaca acctcaaaac agtgttttga
    21481 gctgacttcg tcagtttcat ctacaacctc aaaacagtgt tttgagctga cttcgtcagt
    21541 ttcatctaca acctcaaaaa catgttttga gctgacttcg tcagttctat ctacaacctc
    21601 aaaacagtgt tttgagcaac ctgcggctag cttcctagtt tgctctttga ttttcattga
    21661 gtataaataa aaaaacagaa ctagtctgaa ctagtcctgt ctacttttac ccaatcacac
    21721 ttccatttgg tacagctgga tcaactgtga gaagggttaa tttgccatca tattcagctg
    21781 atagaatcat accctggctg acatattttt tcatcatttt acgtggtttg aggttagcaa
    21841 cgatttgaac tttcttgccg accaattctt gttcatttgg atagtatttt gcaattcctg
    21901 aaagaatctg acgatcttct ccatcaccag catccaagcg gaattgaagc aacttatctg
    21961 aaccttctac tttagacact tctttgactt ctgcgacacg gatttcaacc ttgtcaaagt
    22021 cttcaaactt gatttcatcc ttgtttagtt tgagctcaac ttcgtccgga ttccattctt
    22081 tttcgactgc tggtttattg ccttccattt gttccttgat ataggcgatt tcttcttcca
    22141 tatttagacg tggaaagata ggtgttcctt tggcaactac agtcacatct gctgggaagt
    22201 cagccaaact caagttttca agactagaaa cttcttccaa accaagttga gtcaaaactg
    22261 cacgactagt ttccatcata aatggttcaa tcaagtgagc aactacacga atgctggctg
    22321 ccaagtggct catgacactt gccaattggt cacgaagagc ttcatccttg gccaagaccc
    22381 atggtgcggt ctcatcgatg tatttattgg tacgagagat cagagtccag actgcttcaa
    22441 gcgcacgtgg atagtcaact gcttccatgt gtgtatggaa gtctgcgatt gattgttctg
    22501 caacctcagc aagaacatga tcaaattcag tcacaccttc tacataggca gggatttgtc
    22561 catcaaagta cttattaatc atggaaaccg tacggttaag gaggttccca aggtcattag
    22621 ccaattcata gttgatacgg ccgacatagt cttcaggagt aaaggttccg tctgaaccaa
    22681 ctggaaggtt acgcatgagg tagtaacgaa gtggatctag tccataacgc tctaccaaca
    22741 tttcagggta aacgacattc ccttttgact tagacatttt tccgtctttc atgacaaacc
    22801 aaccatgggc aatcaaacga tcaggtaatt taacatccaa catcataaga aggattggcc
    22861 agtagataga gtggaagcga aggatatctt ttcctaccat atggaagact gttccattcc
    22921 agaacttgtc aaagttacca tgttcgtctt gagcgtagcc aagagctgtc gcatagttaa
    22981 gaagggcatc aatccaaacg tagacaacgt gttttggatt tgatgggaca ggcactcccc
    23041 atgtaaaggt tgtacgagat accgccaaat cttccaagcc tggctcgatg aagttgcgta
    23101 gcatttcatt aaggcgacca tctggcgtga taaattcagg atgagctttg aaaaattcga
    23161 ccaaacggtc ttggtatttg ctaaggcgaa ggaagtatga ttcttcagaa acccattcaa
    23221 cctcatgacc tgatggagca ataccaccag tcacatttcc agcttcatca cggaaaactt
    23281 ctgccagctg gctttctgta aagaattctt cgtctgatac tgaataccaa ccagagtatt
    23341 cacccaagta gatatcatct tgagcaagta agcgttcaaa gacctgtgcg acaacttttt
    23401 catggtagtc atcggttgta cggataaatt tatcgtatga gatatctagt aattgccaga
    23461 gttctttaac tccaaccgcc attccatcaa cataggcttg aggtgtaata ccagcttctt
    23521 ccgctttctg ctggattttc tgaccatgtt catcaagacc tgtcagataa aatacatcgt
    23581 agcccatcag gcgtttgtaa cgtgctagga catcacatgc gatagttgtg taggcagaac
    23641 cgatatgaag tttcccagat ggatagtaaa tcggcgttgt aatataaaaa tttttttcag
    23701 acataatttt tcctttccag gcaaatgaaa cctgtttttc taacacttca ttatatcaca
    23761 tttttaatga atttcgatag ggaaatccat acaaaaacaa gatagacgag tgtccatctt
    23821 gttgatctca ttcataacga agggcttcaa ttggatcaag tttcgatgcc ttgttggctg
    23881 gcaagactcc aaaaatcata ccaacactag ccgaaactgc aagactaaat agggcaactg
    23941 ggattgatac tccaacttct ataccttcta ttaaaccttg cagtaacaaa cctgctaagg
    24001 cagttaaacc acttgcaatt gtcaagccaa ttaagccacc taacaaggtc aaaatcatgg
    24061 attcaatcaa aaactgaatt aaaatattgg cacgtgttgc acccaaagct ttacgaagac
    24121 caatctcacg agtgcgctct gtcaccgaaa ccagcatgat gttcatgaca ccagttcctc
    24181 caacaaagag agaaatccct gcgatggaac taataatcgt cgtcataaaa ctaaacgatt
    24241 gttgaatttc tgcaaataca acggactcat ctgccacctg gtattctccc tgttgtaagc
    24301 ctgcaagctc tgtcattttt cgtgccagtt ctggacccag agttggggtt aaactggtat
    24361 cattcactcg aaagacaata ctagctattt catctatatt aaaattcgca gcaagggaga
    24421 tattggtagt aataggcaag ccaccaaacc catatatttt tgacttttta gcctccggac
    24481 tagtataaac cccaatgacc cggtaactaa atccattgac ttctacaacc ttgttaatag
    24541 cctcttgagg agattcaaat aaactaatgg acaattcctc atctagcaaa ataacacttg
    24601 caaactcttt gaaatcttgc tctctcagac tacgacctgc aataatttca ttcttaacag
    24661 cgtccatgta agttctgttt ccacctgtca aattagcatt ctcaaccttt ttatcttgat
    24721 aggtcaagat ggcattcgtt gaattggtta catagtaact atccactccc ttcagtttag
    24781 ctgcctcttg aacccaggat tcttgcggtt ttggcggttc aacaggaact tcctcttcct
    24841 ttccagaaac cgtaaaagct gattgtttct gagtaaaaga cccatcttta ctttttttag
    24901 gagagaaaaa gacgctaata tttttctgag atttagtcat atctttattg acttgacgag
    24961 atagggaatc acccaaagcc ataatcacaa caactgatga aacaccgata ataatcccaa
    25021 tcatagtaag caaagaacgc atcttgtgag ccatgataga tgaaaaggca aatttcagat
    25081 tctgcatctt agttttcctc ctttcctaac tgagcactgt cagacgaaat gaccccatcc
    25141 cgaatgacaa tctgacgttt ggcataggca gcaatctcag gctcatgcgt taccatgata
    25201 atggtttttc cttctttatt caaatcaacc aataattgca taatttggtt acctgttttg
    25261 gtatccaagg ctcctgtcgg ttcatccgct aggataatag aaggattgtt taccaaggca
    25321 cgcgcaatgg ctacacgttg cttttgacca ccagataatt ctgaaggtaa atggtgacta
    25381 cgttctgtca attcaacctt gtctaaatat tcctcagcca acttgcgacg ttttgaagac
    25441 gaaactcctg cgtaaatcaa gggcaattct acattttgca gagcattgag cttcgataga
    25501 agaaagaact gctgaaagac aaaaccgatt tgttggttac ggaccttagc tagttgtttt
    25561 tcaccaagcc cagccacttc ttgaccttca agataatatt ctccactggt tggtgtatcc
    25621 aacatgccaa tcgtattcat cagagtggac ttaccagacc cagatggtcc catgatggct
    25681 acaaattcac cctcattcac ttctagattg atatttttga gaacctgcag ttcttggtca
    25741 ccattacggt aacttctgaa gatatttttt agactaatta gttgcttcat cagccttcac
    25801 ctcttttcct tcttccaagg aagatgttgg attactgatg accttagcac cgttcgttaa
    25861 accagaagtg atttcttgat tttctgcgtc agcatttccc aatgaaacct caactttttt
    25921 agccttttgt tgttcatcca caatccagac ataattttta ctatcatcca ttactagact
    25981 gctaacagga ataagaatag ccttagtttt gcttttaacc tcaatgttga cagaaaaacc
    26041 ttgtttcaaa tcaccaacct cgcctgtcac atcaatagta taagggtatt tagaacctgt
    26101 attattcccg gctgctggac tagctgcttc accattgttt ttaggatagt cagaaatata
    26161 gcttaatttc ccagtccatt ttttatcagg atacacttta gaagtaaagc ttacttcttg
    26221 acctacagaa aggttggcta gattgtactc agacaattct cccttgactt gtaaattttc
    26281 attgctgaca atatgaacca taacttgact cgcccctgtt ggagatttag aaacattgct
    26341 attgacttcg actacagttc cctctagggt actgagaaca gttgttgcat ccaattgact
    26401 ttgagccttg cttaattgcg ctgcagcatc tgcacgcgca tcacgggcat cacccaattg
    26461 agcatcaata gaagcaacag aatttccagc cactggagtt gggctttgca ccgttgcatc
    26521 ttctcctcct actggcgctg gtaactgtgg agcctgagct gaagcggctt catttcgtgc
    26581 ttgattgagt tcattgatat gacgatctgc cttagctact gctcgactag ctgaatcata
    26641 ggccgcctgc gcttctgaac tactgtactt gactaaagcc tgcccttcgc tgaccttatc
    26701 gcccacagaa acaaggattt catctaaatc acccttacta gcatcaaaat aaacatattg
    26761 ttcatttttt gctgttactg tccctgacaa taaaacagag gatgccacgc ttccttcctt
    26821 ggcaacaaca agatgagtag gctcatcttt tacagcagtc tgagaaggtt gtctaaaaag
    26881 taaaatcccc ccggcaccca atacaactac actcgcagca ccgattgctg catacagttg
    26941 ccacttttta gctttaccat tctttttctt cataatgaaa ctccttttct tttttacaat
    27001 actttgctat tataccaaat ttccctccag caaacaatgc agttcagatg gaaataatgg
    27061 cagttcagga ttaaacaatc gttcggaatt ttgcttttct attgtactag atatataata
    27121 cactatcttg acttatttgg caagcttttt tgcaattttt tgtgcgtagc agatttttgc
    27181 aatcaaatca aaaaaagaat aaaatataac tatcaaaaaa gacactctac tatttaaaag
    27241 attacaaagg agttttcaat gagagaatat gatatcattg ctatcggtgg aggtagcgga
    27301 ggaatcgcta ccatgaaccg tgctggtgaa catggagcca aagcagccgt tattgaggaa
    27361 aagaaattag gtggaacctg tgtcaacgtc ggttgtgttc ctaaaaaaat catgtggtac
    27421 ggggcgcaaa tcgctgagac tttccatcaa tttggagaag actacggctt taagactact
    27481 gatcttaact ttgactttgc aaccctacgt cgcaatcgtg aagcctacat tgatcgcgct
    27541 cgttcttctt atgatggtag ttttaaacgc aacggtgtag acttgattga aggtcatgct
    27601 gaatttgtag attctcatac tgtaagcgta aatggtgaac tgattcgtgc taaacatatc
    27661 gtgattgcta caggtgccca tccaagtatt cctaatattc ctggtgctga gctaggtggc
    27721 tcttctgatg atgtatttgc ctgggaagaa cttccagagt caattgccat tctaggcgct
    27781 ggttatatcg ccgttgaatt agctggcgta ctccacactt ttggtgtcaa gacagatctc
    27841 tttgttcgcc gcgatcgtcc tttacgtggt tttgattcct acatcgttga aggtttggtc
    27901 aaggaaatgg aaagaacaaa cttaccactt cacactcaca aagtccctgt caagttagaa
    27961 aaaactactg acggcattac cattcatttc gaagatggta ctagtcacac agctagccaa
    28021 gttatctggg ctacaggtcg ccgtccaaac gttaagggct tgcaacttga aaaagctgga
    28081 gtgactctga acgaacgtgg ctttatccaa gtggatgaat accaaaatac tgttgttgag
    28141 ggaatctatg ctctaggtga tgtaacgggc gagaaagaac tgactccagt tgcaatcaag
    28201 gccggacgta ccctatctga acgtctcttt aacggaaaaa ctactgcaaa aatggattac
    28261 tcaactattc caactgttgt cttttcacac cctgctatcg gaactgttgg tttgacagaa
    28321 gagcaagcta ttaaagaata cggtcaagac caaatcaagg tttataaatc aagctttgca
    28381 tctatgtact ctgcttgcac tcgcaaccgt caagaatccc gtttcaaact cataacagct
    28441 ggttcagaag aaaaagttgt cggacttcat ggaattggct acggcgttga tgaaatgatt
    28501 cagggatttg ccgttgctat caaaatggga gcaaccaagg ctgactttga tgcaactgtg
    28561 gcaattcacc caactgcatc tgaagaattt gtaaccatgc gttaatcgaa acaaaagaag
    28621 ctgatataaa tatgtctgct tcttttt
//
LOCUS       DAVBEO010000027        27272 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 009
            SAMEA1678075-rid20185393.denovo.027, whole genome shotgun sequence.
ACCESSION   DAVBEO010000027 DAVBEO010000000
VERSION     DAVBEO010000027.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678075
            Sequence Read Archive: ERR226392
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 27272)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27272)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980207.1
            Genome Coverage       :: 150x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:50:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 72 of 147
            Pseudo Genes (incomplete)         :: 72 of 147
            Pseudo Genes (internal stop)      :: 42 of 147
            Pseudo Genes (multiple problems)  :: 32 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27272
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678075-rid20185393.denovo.027"
                     /strain="KS 009"
                     /db_xref="taxon:1313"
     gene            225..1907
                     /locus_tag="VQ543_001177"
     CDS             225..1907
                     /locus_tag="VQ543_001177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000656554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2611904.1"
                     /translation="MKEAIIEWKDFSFRYETQQEPTLQGIDLTIYKGEKVLIVGPSGS
                     GKSTLGQCLNGIIPNIYKGQTYGEFLIKGQTAFDMSIYDKSHLVSTVLQDTDGQFIGL
                     SVAEDLAFALENDVTALDEMKGRVYKWAEKLDLLPLLDQRPQDLSGGQKQRVSLAGVL
                     IDESPILLFDEPLANLDPKSGQDIIELIDQIHKEEGTTTLIIEHRLEDVLHRPVDRIV
                     LINDGRILFNGSPDQLLATDLLTQNGIREPLYLTTLRQLGVDLVKEEQLANLDNMSIS
                     KGQVQLQNELVKETPELQSLFKLEDVSFSYDDRPILKSLHLDIKKGEKIAIVGKNGAG
                     KSTLAKAISSFIQTEGRYLWEKQDIKGDSVAERAERVGYVLQNPNQMISTNMIFDEVA
                     LGLRLRGVDEKEIETRVYETLKICGLYEFRNWPISALSFGQKKRVTIASILVLGAEII
                     LLDEPTAGQDQKNYTEIMEFLEELHRKGHTIVMITHDMQLMLDYSDRVLVMVDGELIA
                     DTVPASLLSDPELLVKANLKETSIFNLAKKLDVDPLDLTAFYKERREGCKLN"
     gene            1892..2722
                     /locus_tag="VQ543_001178"
     CDS             1892..2722
                     /locus_tag="VQ543_001178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HET2611905.1"
                     /translation="MQAKLIGYQHRDTVIHRLSGAGKLLFFILVSLAAMISYDTRMLL
                     LIAIFSVFLLYLSEIRFKDVSFVAVFATVFAVLNVLMVYLFSPEYGVGLYGERSVIWQ
                     GIGVYTLTSQELFYLLNLAIKYLCTIPLAIIFLMTTHPSQFASSLNQIGVPYKIAYSV
                     SLTLRYIPDLQEEFFTIKMSQEARGMELSKKASLMQRIKGNLLIITPLIFSSLERIDT
                     IATAMELRRFGKEKKRTWYSYQALKKGDYITLLLATLFLVASLLLSLQNQGRFYNPWK
                     "
     gene            2915..3418
                     /locus_tag="VQ543_001179"
     CDS             2915..3418
                     /locus_tag="VQ543_001179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000181367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (cytidine(34)-2'-O)-methyltransferase"
                     /protein_id="HET2611906.1"
                     /translation="MTNHIVLFEPQIPQNTGNIARTCAATNSPLHIIKPMGFPIDDRK
                     MKRAGLDYWDKLEIYFYESLEDFISQMKGKLYLISKFAEKVYSEVDLSTDEDHYFLFG
                     REDKGLPEDFMREHPEKALRIPMNDEHVRSLNVSNTVCMIVYEALRQQNFAGLELVHT
                     YEVDKLK"
     regulatory      3472..3706
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            3871..4434
                     /locus_tag="VQ543_001180"
     CDS             3871..4434
                     /locus_tag="VQ543_001180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HET2611907.1"
                     /translation="MTNTRRLSTIAILSAISFVLMYFDFPLLPAASFLKIEFSILPVL
                     VGLVVMDLPAALGVLLLRSLLKLLLNSQGVNTYIGLPMNIVALGVFVIVFALIWKKER
                     TTLRFLLGSLAGTIGLTVAMLVLNYVYAVPLYAKFANFDIGKILGLSNYLMTMVLPFN
                     LIEGVIFSVSFWLLYILLKPTLKHYER"
     gene            4448..5074
                     /locus_tag="VQ543_001181"
     CDS             4448..5074
                     /locus_tag="VQ543_001181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001853067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HET2611908.1"
                     /translation="MKGSFALLLFVILGYMVKFYPEMLVNFDQSIQTAIRGDLPDYLT
                     ILFRSLTRLIDIPVIITWVVIIAFVFYRKRWKIESFFMLGNLTLAGLLIVTFKNIYQR
                     PRPAILHLVEEKGFSFPSGHSLAVTLMVGTLIVILSQRIKDQVWRKIVQIVLGLYLVS
                     VLVSRVYLGVHYPSDVLASLCVGLGALFIEFPFYDKLRFQWRFKGKQK"
     gene            5186..6058
                     /locus_tag="VQ543_001182"
     CDS             5186..6058
                     /locus_tag="VQ543_001182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000525616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET2611909.1"
                     /translation="MGMLLATRLKNKRKELKLSQKELAEGICEQGQISRMEQGKYSPG
                     SELLFQLSKRLKVSMDYFFEDTEVSSLENIDKFKELSKKFLDEREYESLHYIYELEKS
                     KRARLSAKDQIYLDWIDTLVQFCYLNHQTGAVAKLEKILLSLKKSDFYYLQLGNTLAN
                     FYFDMGQEDTYQELYQLLKENLQSLSVHHLEQLELMIKFRYNYCRYLWLNERTSEAIE
                     EITETIAICKRYNSSYRLADLYCLLGSISEGFAERDRILGFYQVSYQLYKHEENQRMM
                     LEIEKEMKLLESED"
     gene            6188..6325
                     /locus_tag="VQ543_001183"
     CDS             6188..6325
                     /locus_tag="VQ543_001183"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2611910.1"
                     /translation="MKRSQVVKRCILIALLLLFLLNVLSGSLSVTTRGVDPRPAYGVS
                     L"
     gene            6749..7663
                     /locus_tag="VQ543_001184"
     CDS             6749..7663
                     /locus_tag="VQ543_001184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000781144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ThiF family adenylyltransferase"
                     /protein_id="HET2611911.1"
                     /translation="MKLYQINDGIQIFESSNLEKIVIRNYRNGKKITIDHQPLLKKLL
                     LFLEVPKREEEILLYLPELSNKTLRSVLTNFMSLNIIHCQDTLIIHKKINILIIGLGT
                     TGGYLADGLCRSNINSKLFLLDKDRVDETNVGRQIYLRDDIGQYKVDVFKQKFSDKEI
                     KVFKIFINSKKDLEKICKREGIDLVIQCGDSPSPRELGKIVNTVCDTLQIPYIVNTGY
                     MSNVVPLPEFYYPNNRYNFNYKHQFSDEKLLFSQVLSKADYMVAIQSSFVMLMQIKNF
                     IFNEEPIYYGYRGYYNSVTLAWEVEKID"
     gene            7656..8669
                     /locus_tag="VQ543_001185"
     CDS             7656..8669
                     /locus_tag="VQ543_001185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000170500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2611912.1"
                     /translation="MTKYLELDYSHSYILEGFRKNDAFIENHKECLDMLSDKIWRDNK
                     YMNTEKNISSPTRTILSRYTCNILSSLFIDISKNSIEKLIVTCENSDLNWIYNYYKSV
                     YNGVFCELRQLIQQYCKVKDKYEKWLFIKAIINQGIRQNEKEVVEFFLKQLKDNNQGI
                     FDYINSFSFYLLKFYSKDKSRIFLEEQLDIDDFLGSDKEDYARSLVFKNYASLLPDTS
                     ELKRNIMEKCLSQTPQDTDLWKEWFETYASQKEIRQKATEIFKHGYSDISLLKLVKIE
                     PDDTESLIRMIILCTSDLNSNIARYLISFLSDGRLKEFLELFVENFDFLNIIEGKTSE
                     INF"
     gene            8653..10245
                     /locus_tag="VQ543_001186"
     CDS             8653..10245
                     /locus_tag="VQ543_001186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001236730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2611913.1"
                     /translation="MRLIFRIIRKDIILYSILTFLLSIAMVSEAFLMQFIVDSIKFGE
                     KKYVLISIFIVIFLILQTLLYYYQQFLTAVLSKKSAYEYRKLIFKNIQQTSLRLVTGE
                     KNDSILASLTTQIDQIEYNYFYSVYWGGYLLCQLVVAIVMSLYLNPLMSVLTICLSLP
                     NLFVALLFKNSLEQKQEELINETNSSIAVTQDLIEGITDWKIANREPNIFRVFESKTL
                     KLLEKQVKVEKFQYIVVSLNQLFSNVLYFGSWIVGGFLIIRGQLSLGSLIAFSQLLAR
                     ISYPVYASSDLLSKYISGKKIVEILSKEFIFSDESRNYPDEFNVISFEHYFTNIDEKD
                     MPFDKEFYKNKKYLLKGKSGSGKTTILKSILREYDDYSGIVKINGVDVRDIKESVLFD
                     NIAYVSQKPHLFSASLRDNLTLFSEDFTDNEIVEVLKFVELSKWANKDCLDMMLSNDD
                     IKLSGGEVKRVSLARALLMNKNILLLDEFSAGIDYETLLKIEKKLIDLDKMIIYVTHV
                     DIDRSGKQFDDVIDLDCLFISS"
     gene            10437..11340
                     /locus_tag="VQ543_001187"
                     /pseudo
     CDS             10437..11340
                     /locus_tag="VQ543_001187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001091364.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
     gene            11358..11495
                     /locus_tag="VQ543_001188"
                     /pseudo
     CDS             11358..11495
                     /locus_tag="VQ543_001188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001853067.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
     gene            11523..11864
                     /locus_tag="VQ543_001189"
     CDS             11523..11864
                     /locus_tag="VQ543_001189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000867291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2611914.1"
                     /translation="MKVNIADLHPTQLYLSEKKLQDIQMLYQSAETIQVDPISILAFG
                     DCLLITDGHHRAYQALLAGRDTISAEWDRDGGDELYHLYAQACEERKIYSVFDLKNHI
                     LPLWIGMVSFF"
     gene            11837..12148
                     /locus_tag="VQ543_001190"
                     /pseudo
     CDS             11837..12148
                     /locus_tag="VQ543_001190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000333655.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
     gene            12276..12863
                     /locus_tag="VQ543_001191"
     CDS             12276..12863
                     /locus_tag="VQ543_001191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit delta"
                     /protein_id="HET2611915.1"
                     /translation="MELEVFAGQEKSELSMIEVARAILELRGRDHEMHFSDLVNEIQN
                     YLGTSNSDIREALPLFYTELNFDGSFISLGDNKWGLRSWYGVDEIDEEIIALEENDDD
                     EVAPKAKKKRVNAFMDGDSDAIDYNADDPEDEDAYEADPALSYDDENPDDEKNEVEAY
                     DAEINEIAPDDLGEDVDLNEDDDEFSDDDAETSEE"
     gene            13253..14860
                     /locus_tag="VQ543_001192"
     CDS             13253..14860
                     /locus_tag="VQ543_001192"
                     /EC_number="6.3.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CTP synthase"
                     /protein_id="HET2611916.1"
                     /translation="MSTKYIFVTGGVVSSIGKGIVAASLGRLLKNRGLKVTIQKFDPY
                     INIDPGTMSPYQHGEVFVTDDGAETDLDLGHYERFIDINLNKYSNVTTGKIYSEVLRK
                     ERRGEYLGATVQVIPHITDALKEKIKRAALTTDSDVIITEVGGTVGDIESLPFLEALR
                     QMKADVGADNVMYIHTTLLPYLKAAGEMKTKPTQHSVKELRGLGIQPNMLVIRTEEPA
                     GQGIKNKLAQFCDVAPEAVIESLDVEHLYQIPLNLQAQGMDQIVCDHLKLDAPAADMT
                     EWSAMVDKVMNLKKQVKISLVGKYVELQDAYISVVEALKHSGYVNDVEVKINWVNAND
                     VTAENVAELLSDADGIIVPGGFGQRGTEGKIQAIRYARENDVPMLGVCLGMQLTCIEF
                     ARHVLGLEGANSAELAPETKYPIIDIMRDQIDIEDMGGTLRLGLYPSKLKRGSKAAAA
                     YHNQEVVQRRHRHRYEFNNAFREQFEAAGFVFSGVSPDNRLVEIVEIPENKFFVACQY
                     HPELSSRPNRPEELYTAFVTAAVENSN"
     gene            complement(15419..17050)
                     /locus_tag="VQ543_001193"
     CDS             complement(15419..17050)
                     /locus_tag="VQ543_001193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004251733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na/Pi cotransporter family protein"
                     /protein_id="HET2611917.1"
                     /translation="MSINWQEILFHFLGGLGLFLYSIKTMGDGLQQAAGDRLRFYIDK
                     YTSNPFFGVLVGIGMTALIQSSSGVTVITVGLVSAGLLTLRQAIGIVMGANIGTTVTS
                     FLIGFKLGNYALPMLFIGAVCLFFTKNRTVNNIGRILFGVGGIFFALNLMSGAMAPLK
                     DLQVFKDYMIELSKNPVLGVFVGTGLTLLIQASSATIGILQNLYAGNLIDLQGALPVL
                     FGDNIGITITAIIASLGANIAAKRVAGAHVAFNVIGTVVCVIFLVPFTVLIHWFEATL
                     NLAPEMTIAFAHGTFNITNTIVQFPFIGALAYFVTKIIPGEDEVVKYEPLYLDEHFIK
                     QAPSIALGNAKKELLHLGNYAAKAFDLSYKYIIDLDEKVAEKGHKTEEAINTIDEQLT
                     RYLIALSSEALSQKESEVLTNILDSSRDLERIGDHTEALLNLTDYLQRKNVEFSDAAL
                     KELEEVYRQTSDFIKDALDSVENNDIEKARSLVERHEAINKIERVLRKTHIKRLNKGE
                     CSTQAGVNFIDIISHYTRVSDHAMNLAEKVFAEQI"
     gene            17343..22322
                     /locus_tag="VQ543_001194"
     CDS             17343..22322
                     /locus_tag="VQ543_001194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000795197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacterial Ig-like domain-containing protein"
                     /protein_id="HET2611918.1"
                     /translation="MKNPFFERRCRYSIRKLSVGACSLMIGAVLFAGPALAEETAVPE
                     NSGANTELVSGESEHSTNEADKQNEGEHARENKLEKAEGVAIASETASPASNEAATTE
                     TAEAASAAKPEEKASEVVAETPSAEAKPKSDKETEAKPEATNQGDESKPAAEANKTEK
                     EVQPDVPKNTEKTLKPKEIKFNSWEELLKWEPGAREDDAINRGSVVLASRRTGHLVNE
                     KASKEAKVQALSNTNSKAKDHASVGGEEFKAYAFDYWQYLDSMVFWEGLVPTPDVIDA
                     GHRNGVPVYGTLFFNWSNSIADQERFAEALKQDADGSFPIARKLVDMAKYYGYDGYFI
                     NQETTGDLVKPLGEKMRQFMLYSKEYAAKVNHPIKYSWYDAMTYNYGRYHQDGLGEYN
                     YQFMQPEGDKVPADNFFANFNWDKAKNDYTIATANWIGRNPYDVFAGLELQQGGSYKT
                     KVKWNDILDENGKLRLSLGLFAPDTITSLGKTGEDYHKNEDIFFTGYQGDPTGQKPGD
                     KDWYGIANLVADRTPAVGNTFTTSFNTGHGKKWFVDGKVSKDSEWNYRSVSGVLPTWR
                     WWQTSTGEKLRAEYDFTDAYNGGNSLKFSGDVAGKTDQDVRLYSTKLEVTEKTKLRVA
                     HKGGKGSKVYMAFSTTPDYKFDDADAWKELTLSDNWTNEEFDLSSLAGKTIYAVKLFF
                     EHEGAVKDYQFNLGQLTISDNHQEPQSPTSFSVVKQSLKNAQEAEAVVQFKGNKDADF
                     YEVYEKDGDSWKLLTGSSSTTIYLPKVSRSASAQGTTQELKVVAVGKNGVRSEAATTT
                     FDWGMTVKDTSLPKPLAENIVPGATVIDSTFPKTEGGEGIEGMLNGTITSLSDKWSSA
                     QLSGSVDIRLTKPRTVVRWVMDHAGAGGESVNDGLMNTKDFDLYYKDADGEWKLAKEV
                     RGNKAHVTDITLDKPITAQDWRLNVVTSDNGTPWKAIRIYNWKMYEKLDTESVNIPMA
                     KAAARSLGNNKVQVGFADVPAGATITVYDNPNSQTPLATLKSEVGGDLASAPLDLTNQ
                     SGLLYYRTQLPGKEISNVLAVSVPKDDRRIKSVSLETGPKKTSYAEGEDLDLRGGVLR
                     VQYEGGTEDELIRLTHAGVSVSGFDTHHKGEQNLTLQYLGQPVNANLSVTVTGQDEAS
                     PKTILGIEVSQEPKKDYLVGDSLDLSEGRFAVAYSNDTMEEHSFTDEGVEISGYDAQK
                     TGRQTLTLRYQGHEVNFDVLVSPKAALNDEYLKQKLAEVEAAKNKVVYNFASPEVKEA
                     FLKAIEAAEQVLKDHETSTQDQVNDRLNKLTEAHKALNGQEKFKEEKTELDRLTGEVQ
                     ELLAAKPNHPSGSALAPLLEKNKALVEKVDLSPEELATAKQSLKDLVALLKEDKPAVF
                     SDSKTGVEVHFSNKEKTVIKGLKVERVQASAEEKKYFAGEDAHVFEIEGLDEKGQDVD
                     LSYASIVKIPIEKDKKVKKVFFLPEGKEAVELAFEQTDSHVIFTAPHFTHYAFVYESA
                     EKPQPAKPAPQNKVLPKPTYQPASDQQKAPKLEVQEEKVAFHRQEHENAEMLVGEQRV
                     IIQGRDGLLRHVFEVDENGQRRLRSTEVIQEAIPEIVEIGTKVKTVPAVVATQEKPAQ
                     NTAVKSEEASKQLPNTGTADANEALIAVLASLGLASLALTLRRKREDKD"
     gene            22412..23608
                     /locus_tag="VQ543_001195"
     CDS             22412..23608
                     /locus_tag="VQ543_001195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate kinase"
                     /protein_id="HET2611919.1"
                     /translation="MAKLTVKDVDLKGKKVLVRVDFNVPLKDGVITNDNRITAALPTI
                     KYIIEQGGRAILFSHLGRVKEEADKAGKSLAPVAADLAAKLGQDVVFPGVTRGAELEA
                     AINALEDGQVLLVENTRYEDVDGKKESKNDPELGKYWASLGDGIFVNDAFGTAHRAHA
                     SNVGISANVEKAVAGFLLENEIAYIQEAVETPERPFVAILGGSKVSDKIGVIENLLEK
                     ADKVLIGGGMTYTFYKAQGIEIGNSLVEEDKLDVAKALLEKANGKLILPVDSKEANAF
                     AGYTEVRDTEGEAVSEGFLGLDIGPKSIAKFDEALTGAKTVVWNGPMGVFENPDFQAG
                     TIGVMDAIVKQPGVKSIIGGGDSAAAAINLGRADKFSWISTGGGASMELLEGKVLPGL
                     AALTEK"
     gene            23744..24271
                     /locus_tag="VQ543_001196"
     CDS             23744..24271
                     /locus_tag="VQ543_001196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000119911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HET2611920.1"
                     /translation="MSYFKKYKFDKSQFKLGMRTFKTGIAVFLVLLIFGFFGWKGLQI
                     GALTAVFSLRESFDESVHFGTSRILGNSIGGLYALVFFLLNTFFHEAFWVTLVVVPIC
                     TMLTIMTNVAMNNKAGVIGGVAAMLIITLSIPSGETILYVFVRVLETFMGVFVAIIVN
                     YDIDRIRLFLEKKEK"
     gene            24348..24704
                     /gene="glnR"
                     /locus_tag="VQ543_001197"
     CDS             24348..24704
                     /gene="glnR"
                     /locus_tag="VQ543_001197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000659547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor GlnR"
                     /protein_id="HET2611921.1"
                     /translation="MKEKEFRRNMAVFPIGSVMKLTDLSARQIRYYEDQELIKPDRNE
                     GNRRMYSLNDMDRLLEIKDYISEGYNIAAIKKKYAEREAKSKKAVSQTEVRRALHNEL
                     LQQGRFASVQSPFGRG"
     gene            24741..26087
                     /gene="glnA"
                     /locus_tag="VQ543_001198"
     CDS             24741..26087
                     /gene="glnA"
                     /locus_tag="VQ543_001198"
                     /EC_number="6.3.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glutamate--ammonia ligase"
                     /protein_id="HET2611922.1"
                     /translation="MPITAADIRREVKEKNVTFIRLMFSDILGTMKNVEIPATDEQLD
                     KVLSNKVMFDGSSIEGFVRINESDMYLYPDLDTWTVFPWGDENGSVAGLICDVYTTEG
                     EPFAGDPRGNLKRALRHMEEVGFKSFNLGPEPEFFLFKLDENGDPTLEVNDKGGYFDL
                     APTDLADNTRREIVNVLTKMGFEVEASHHEVAVGQHEIDFKYDEVLRACDKIQIFKLV
                     VKTIARKHGLYATFMAKPKFGIAGSGMHCNMSLFDAEGNNAFFDPNDPKGMQLSETAY
                     HFLGGLIKHAYNYTAIMNPTVNSYKRLVPGYEAPVYIAWAGRNRSPLVRVPASRGMGT
                     RLELRSVDPMANPYIAMAVLLEVGLYGIENKIEAPAPIEENIYIMTAEERKEAGITDL
                     PSTLHNALKALTEDEVVKAALGDHIYTSFLEAKRIEWASYATFVSQWEIDNYLDLY"
     gene            complement(26183..26302)
                     /locus_tag="VQ543_001199"
     CDS             complement(26183..26302)
                     /locus_tag="VQ543_001199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine synthetase"
                     /protein_id="HET2611923.1"
                     /translation="MPDIVFEIEFFHSDSLIFFYTSDDKSNSQKSQEDFSKNK"
     gene            26790..27272
                     /locus_tag="VQ543_001200"
                     /pseudo
     CDS             26790..27272
                     /locus_tag="VQ543_001200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000187281.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
BASE COUNT         8592 a         4568 c         5792 g         8320 t
ORIGIN      
        1 catacctacg gcaaggcgaa actgacgtgg tttgaagaga ttttcgaaga gtataaaatg
       61 atggggaagg ctgggcaact agtctttttc gatgtttata gattagttag gcaagtaagc
      121 taggatagga atctttttgg tgctaagatt ttaagagaag agactgcaag aagggcttga
      181 tttatgataa aatagaagtc taagaagcga atgaagagag taagatgaaa gaagctataa
      241 ttgagtggaa ggatttctct ttccggtatg aaacacaaca agaaccgacc ttgcaaggga
      301 tagacttgac catttacaag ggagagaaag tcttaattgt tggaccatct ggatcaggta
      361 aatctacctt gggtcagtgt ttgaatggga ttattcccaa tatttacaag ggtcagacat
      421 atggagaatt tttgataaag ggtcaaacag cctttgatat gagcatctat gataagtctc
      481 atctggttag cacagttttg caggatacag atgggcagtt tattggcttg tctgtggcag
      541 aagatttggc gtttgctctg gaaaatgatg tgacagccct agatgagatg aaaggtcgtg
      601 tttataaatg ggctgaaaag ctggaccttc ttcctttact ggatcagcgt cctcaggatt
      661 tgtcaggtgg acaaaagcag cgagtcagtc tggctggtgt cttgattgat gaaagtccga
      721 ttctcttgtt tgatgagcca ctcgccaatc tagatcccaa gtcaggtcag gatattatcg
      781 aattgattga ccagattcat aaggaagagg ggacgacgac tcttattatc gagcaccgtt
      841 tggaggatgt tctgcatcgc cctgtggatc ggattgtctt gataaacgat ggtcgtatcc
      901 tttttaatgg gagccctgac cagttgcttg cgactgattt attgactcaa aatggaattc
      961 gagaacccct ttatctaacc actctccgtc aattaggtgt ggacttagtc aaggaagaac
     1021 agttagcgaa tctggataac atgtctatct caaaaggtca ggttcagctg cagaatgaac
     1081 tggtaaaaga aactccagaa ttgcagtcac tctttaaatt agaggacgtg tctttctctt
     1141 atgatgatag accgatttta aaatccctac atttagatat taaaaagggt gaaaagattg
     1201 ctattgtcgg aaaaaatgga gcagggaaat caactctagc caaggctata agtagcttta
     1261 ttcagacgga aggacgctat ctttgggaaa aacaggatat aaaaggcgat tctgttgcag
     1321 agcgggcgga acgagtaggc tatgtgctac aaaatcctaa tcaaatgatt tcaaccaata
     1381 tgatttttga tgaggtggct ctagggctcc gtttgcgagg tgtggatgag aaggaaattg
     1441 aaacgagagt ctatgaaacc ttgaaaatct gtggacttta tgaattccgt aattggccta
     1501 tttctgccct gtcatttggt cagaaaaaac gtgtcaccat tgcttcaatt ttggtcttag
     1561 gagctgaaat tattctccta gatgaaccga ctgcaggtca agatcagaag aactatactg
     1621 agattatgga atttctcgaa gagttacatc gaaaagggca taccattgtc atgattaccc
     1681 atgatatgca attgatgctg gattattcag accgagtcct tgtcatggtg gatggagaat
     1741 tgattgccga tactgttcca gccagtctgt tgagcgatcc tgagctgtta gtaaaagcca
     1801 atctaaaaga aacctccatc tttaacttgg ctaagaaact agatgtggat ccactggatt
     1861 taacggcatt ttacaaagaa aggagagagg gatgcaagct aaattaatcg gttaccagca
     1921 tagagatact gtgattcatc gcttgtcagg agctgggaaa cttctctttt tcattctggt
     1981 atcattggcg gccatgatta gctatgatac cagaatgctc ttgctgattg ccatcttttc
     2041 agtctttctc ctctatttat cagaaattcg ctttaaagat gtttcctttg tagccgtttt
     2101 tgcgacggta tttgccgttt taaacgtttt gatggtctat ctcttttctc ccgagtatgg
     2161 ggttggactt tatggagaga gaagtgtgat ttggcaggga atcggtgtct acactctaac
     2221 cagccaggag ctcttttatc tgctaaattt ggccattaag tatctttgca ccattcctct
     2281 ggctattatc tttttgatga caacccatcc tagtcagttt gcttccagtt taaatcaaat
     2341 tggtgtgccc tataagattg cttattctgt cagcctgacc ttgcgctata ttccagattt
     2401 gcaggaagaa ttctttacta tcaagatgtc tcaggaggcg cgtgggatgg aattatccaa
     2461 gaaagcttct cttatgcaac gaatcaaagg caatctgctc attattacgc ccttgatttt
     2521 tagctcgcta gaacgcattg ataccattgc gactgccatg gagcttcgcc gctttgggaa
     2581 agaaaaaaaa cgcacatggt atagttatca ggccttgaaa aaaggagact atattacctt
     2641 gctcttggca accttgtttt tagtagctag tttactactt agcttgcaga atcagggacg
     2701 attttacaac ccttggaaat agcttgaaaa aattgaaaaa atcaagtcgt ttctattgac
     2761 aatgattctg aaagtgttat actaagaaag tagtttcgct gatttacttc aaacctgttg
     2821 tgaggtaagt taacgatgcc ttaaccacgc tgtttgctga gcttgactcc gggcagtgtg
     2881 gctatttttt tgcaatggtg aaaggaagca agtcatgaca aatcacattg tattatttga
     2941 acctcaaatt ccacaaaata cgggcaatat cgcgcgtact tgcgctgcga ccaattctcc
     3001 cctccacatc atcaagccta tgggctttcc tattgatgac cgcaagatga agcgggctgg
     3061 attggattac tgggataagc tagagattta tttttacgag agtttggaag atttcatatc
     3121 tcagatgaag ggaaaactct atctgatttc gaaattcgcg gaaaaagtct attctgaggt
     3181 ggatttatcg actgacgagg accattattt tctctttgga cgtgaagaca agggcttacc
     3241 tgaagatttt atgcgagaac atcctgagaa ggctctccgt attcccatga atgatgaaca
     3301 tgtccgcagt ctcaatgtgt ctaataccgt ctgcatgatt gtctatgagg ctcttcgcca
     3361 gcagaacttt gcaggtcttg aactcgtcca tacctatgaa gtggataaat tgaaataaaa
     3421 aatgaaaatg aacaaaatgc ttgcgcttgc aagcgttttt tgttatgata aaagagtctt
     3481 cagggcaggg tgtgattccc gaccggcggt gactttaact aggaaatgat cttttccttt
     3541 tatactttgt tgacaagctt tgcctaacca gaagttatgc ctacagcttg tcgcctagtc
     3601 taaaagaaaa atctctattt ccttctcttt aaagaagtcc gcgagcgcaa gctgatgtgg
     3661 tgagattcca caaccgacag tatagtctgg atgggagaag acgaaagaat agctttgtct
     3721 gttttgatag atttatagcc ggattgtaac cacttgcttt gtttttcttt aatagagtag
     3781 gagggaactt ttgggatata aaaagtgaga atagatagag gaatcctttc caacttcttc
     3841 tgattttata gaaaattgga ggaacctgtt atgacaaaca cacgtcgact ttcgaccatt
     3901 gcaattttat cagccatctc atttgtgctg atgtactttg actttccgct tttaccagcg
     3961 gcatctttcc tcaagatcga atttagtatc ttgccagtcc ttgtgggtct ggtggtcatg
     4021 gatttgcctg ctgctctagg agtgctcttg cttcgctcac tcttgaaatt gcttcttaac
     4081 agccaaggag tgaatactta cattggtttg ccgatgaata tcgtagcttt gggagttttt
     4141 gtcatcgtat ttgctttgat ttggaaaaag gaacggacaa cccttcgttt cctactaggc
     4201 tctctagctg ggactattgg tttaaccgtg gctatgttag ttctcaacta tgtttatgct
     4261 gttcctttgt acgctaagtt tgctaacttt gatattggaa aaattttggg actttccaac
     4321 tacctaatga ccatggtatt accttttaac ttgattgaag gtgtaatctt ttccgtttca
     4381 ttctggttgt tgtacattct cttgaaacca accttaaaac attatgaaag ataaacaaac
     4441 atttttaatg aagggcagtt ttgccctttt acttttcgtt attcttggct atatggtcaa
     4501 attttaccct gaaatgttgg tcaattttga ccaatcgatt cagactgcca ttcgaggaga
     4561 cttaccagat tatttgacta ttctttttcg atccctcaca cgtctgattg atattccagt
     4621 gattatcact tgggttgtca ttatagcttt tgtcttttat cgtaagcgat ggaagataga
     4681 aagtttcttc atgctgggaa atctgacttt ggcaggtctt ttaatcgtga cctttaaaaa
     4741 tatctaccag cgcccacgac cagctatctt acatctggtg gaggagaagg gattttcctt
     4801 cccaagtggg cattctctgg ctgtaacgct gatggtaggg actttgattg ttattcttag
     4861 tcagcggatt aaagatcagg tctggagaaa aatcgtacaa atcgtccttg gcctctacct
     4921 agtcagtgtg ctggtatcaa gagtctatct gggagttcat tacccatcag atgttcttgc
     4981 cagtctctgt gtgggcttgg gagccctgtt tatcgagttt cccttttatg ataagctccg
     5041 cttccaatgg cgatttaaag gcaaacagaa atgatggaaa agataaaaaa ttgtacaaat
     5101 acaaatagaa ccatatgaaa tatatacttg aaacatgttt tggagtttga tatattttaa
     5161 taaataaagc aaggaggaag aaagtgtggg tatgttatta gcgacacgct taaaaaataa
     5221 aagaaaggaa ttaaaattat ctcaaaaaga attagctgag gggatttgtg agcaagggca
     5281 gattagccgt atggagcaag gtaaatactc acctgggtca gaattactct ttcaactatc
     5341 taagcgattg aaggtgagca tggattattt ctttgaagat actgaggttt ctagtttaga
     5401 aaatattgat aagtttaaag aattatctaa gaaatttttg gatgagaggg aatatgaatc
     5461 tctccattac atctatgaac tggaaaaatc taaacgtgct cgtctatctg ctaaagacca
     5521 gatttatttg gattggattg atacattagt tcaattctgt tatttaaatc atcaaacagg
     5581 ggcagttgcg aaactggaaa aaatactgtt atctctgaaa aaatctgatt tttactatct
     5641 acaactggga aataccttgg ctaattttta ttttgatatg gggcaggaag acacatatca
     5701 ggaactctat caacttttaa aagagaacct ccagtcacta tctgttcatc atttggaaca
     5761 gttagaattg atgattaaat tccgatataa ctattgtaga tatttgtggt tgaatgaacg
     5821 aacatctgaa gctatagaag aaattacaga aacgatagct atttgtaaaa gatataatag
     5881 tagttatcga ttagcagatt tgtattgttt attgggaagt ataagcgagg gctttgctga
     5941 aagggatagg atactaggtt tttatcaagt atcttaccag ctttacaagc acgaagagaa
     6001 ccagagaatg atgctagaaa ttgagaagga aatgaaatta ttggaaagtg aagattaagc
     6061 aaaaagattt gtattcttag ataactttaa tacatattat aaaaaaaata aaaaaatatc
     6121 ataaaaatta ttgacaaacc aaaattgatg tgttagaata tcaccaatag ttaaggaggt
     6181 ttagaagatg aaaagatctc aagttgtcaa acgatgtata ttaattgctt tattgcttct
     6241 atttctactt aatgtgttaa gtggttcttt atctgtaaca actagaggag ttgatccaag
     6301 accagcatat ggagtttcgc tttaaagttg tgcatagttc ttcttttata gacggagagt
     6361 ttttctcaat agtaagtgat tcaaattttg atggatgatt ttccattaaa ttaagtgatt
     6421 gcgaaaactt tttgaaatac attctctttg gatattgaaa gtttgttttg gattttttta
     6481 tgaagcttat cttagctgtt agattggggt tttatgggat ttgtcctcac cgggaaaaaa
     6541 tcttaaatct ttgaagaaag aggtttttat cttatggtta gagatacatc agaagaaatt
     6601 gaagttattg acttgtcttc tatgaccgtt tcctactcat ctgttatgct aggaaactct
     6661 tggatgacgt ggaattgatt tattaagata gattatttgg tttttaccaa aaatctgtct
     6721 ttttaatttt taaaggacta atggtgatat gaaactatat caaataaatg atgggataca
     6781 aatttttgaa agtagtaatc ttgaaaaaat agtaattaga aattatagga atggtaagaa
     6841 aataactatc gatcaccaac cattattaaa aaaattacta ctattccttg aagttcctaa
     6901 acgtgaagaa gaaattctat tatatcttcc agaattatca aataaaacat tacgaagtgt
     6961 tttgacgaat tttatgagtt taaatataat tcattgtcaa gatacattaa taattcacaa
     7021 aaaaataaac atattgataa taggtttagg gactacgggt ggatatctgg cagatgggtt
     7081 atgtcgtagt aatattaatt cgaagctatt tcttttagat aaggatcgtg tagatgagac
     7141 taatgtaggt agacagattt atttaagaga tgatattggt caatataaag ttgatgtatt
     7201 taaacaaaag tttagtgata aagaaataaa ggtattcaaa atttttatta atagtaagaa
     7261 agatttggaa aagatttgca aaagggaggg tatcgatttg gttatacaat gtggtgactc
     7321 cccttcacct cgagaattag gaaaaattgt gaatacagta tgtgatactc tccagatacc
     7381 ttatatagtt aacactggct acatgagtaa tgtagttcct ttgccagaat tttattatcc
     7441 aaataataga tacaatttta attataagca tcaattttca gatgaaaagt tactgttctc
     7501 acaagttttg tctaaagctg attatatggt ggcaattcaa tcatcatttg taatgttaat
     7561 gcaaataaaa aattttatat ttaatgaaga acctatttat tatggttata ggggatacta
     7621 taattctgta acattagcat gggaggtgga aaaaattgac taaatattta gaattggatt
     7681 attctcattc atatattttg gaaggtttta gaaaaaatga tgcgtttatt gaaaatcaca
     7741 aagaatgcct tgatatgtta tcagataaga tttggcgaga taataaatat atgaatacag
     7801 aaaaaaacat atcatcaccg acacgaacaa tcttatcacg ctatacttgt aatattttat
     7861 cgtctttgtt tattgatatt agcaaaaata gcatagaaaa attgatagtg acatgtgaaa
     7921 atagcgatct taattggatt tataattatt ataaatcggt ttacaatgga gtattttgtg
     7981 aattgcgaca acttatacaa cagtactgta aggtgaagga taagtatgaa aagtggcttt
     8041 ttataaaagc tattataaat caaggtattc gtcaaaatga gaaagaagtt gttgaattct
     8101 ttttaaaaca attgaaggat aataatcaag gtatttttga ttacatcaat agttttagtt
     8161 tttatctatt aaagttttat tcaaaagaca aatctcgcat ttttttagaa gagcagctag
     8221 atatagatga ttttttggga tcagataaag aagattatgc taggtcttta gtttttaaga
     8281 attatgcttc tctattgcct gatacttctg aattaaaaag aaatattatg gaaaaatgtt
     8341 taagtcaaac acctcaagat acagatttat ggaaagaatg gtttgaaact tatgccagtc
     8401 agaaagagat tagacaaaaa gcaacggaaa tatttaagca tggttattca gatatttcgt
     8461 tactaaaatt agttaaaatt gagcctgatg acactgagag tttaatcaga atgattatct
     8521 tatgtaccag tgacctaaat agtaatattg caaggtattt gatttcattt ttgagcgatg
     8581 ggcgattaaa agaatttttg gagttatttg ttgaaaattt tgactttttg aatattattg
     8641 agggaaaaac tagtgagatt aatttttaga ataattagaa aagatattat attatattct
     8701 atattaacat ttttgctatc aatagcgatg gtaagcgaag catttttgat gcaatttatt
     8761 gttgattcaa ttaaatttgg tgaaaagaag tatgttttga tttctatttt tattgtaatt
     8821 tttttgattc ttcagacttt attgtattac tatcaacaat ttcttacagc tgtattaagt
     8881 aaaaaatctg catatgagta ccgtaaatta atttttaaaa atattcagca gacttctctt
     8941 aggcttgtta caggtgaaaa aaatgatagt attctagctt ctttgacaac gcaaatcgat
     9001 caaatagaat ataattattt ttattctgtt tattggggtg gatatttgct ttgccaatta
     9061 gtggtagcta tagttatgtc gctttatcta aatccattga tgtctgtatt aaccatttgc
     9121 ttaagtctcc ctaatttatt tgtagcactt ctttttaaaa actccttgga acaaaagcaa
     9181 gaagagctaa ttaatgagac aaattcctca atagcagtta ctcaagattt aattgaggga
     9241 attactgatt ggaaaattgc aaatagagaa cctaatatat ttagagtgtt tgaaagcaaa
     9301 acattgaagc ttttagagaa gcaagtgaag gtagaaaaat ttcaatacat tgttgttagt
     9361 ttaaatcaat tgttttcaaa tgttttatat tttggtagtt ggatagtagg tggattcttg
     9421 attatacggg ggcaactttc attagggagt ttgatagcgt tctctcaatt attagcaaga
     9481 atttcttacc ctgtttacgc ttcttcggat ttattgtcaa aatatattag cggtaaaaaa
     9541 attgtagaaa ttctttctaa agaatttata ttttcagacg aaagcagaaa ttatccagat
     9601 gagtttaatg ttatttcatt tgaacattat tttacaaaca ttgacgaaaa ggatatgcct
     9661 tttgataaag aattttacaa aaataaaaaa tatttgttga aagggaaaag tggtagtggg
     9721 aaaacaacaa ttttaaaatc gattttacga gagtatgatg attatagtgg aattgtaaaa
     9781 attaatgggg tagatgttag ggatataaaa gagagtgttc tttttgacaa tatagcttat
     9841 gtttcccaaa aacctcactt gttcagcgca agtcttagag acaacctgac attattttct
     9901 gaagacttca ctgataatga gatagttgag gttttaaaat ttgttgaatt atctaaatgg
     9961 gctaataaag attgcttgga tatgatgctt tcaaatgatg atataaaatt atcaggaggg
    10021 gaggtcaaaa gggtttcttt agctcgagcc ttattgatga ataagaatat tctgttattg
    10081 gatgagttct ctgctgggat tgattatgaa acattgttaa aaatagagaa gaaactcatt
    10141 gatttggata agatgattat ttacgtgacg catgtggata tagatagatc cggcaaacag
    10201 tttgatgatg tcattgattt ggattgtctt tttatatcct cgtgacatga gagttgagtc
    10261 agttgaatta ttttgtcact ctgtttagtt cttgttggta gtgtcaggta atctttgtta
    10321 atttttcagg aagtctattg aaatatcctc ttggttatat attacgagga gtaattaatg
    10381 gatattctcg agaattcaat acaacaattt gattctaaag ttaagtatgt ttctttattt
    10441 gcggaatcaa tcttttatca gataccatga gctattttgc aggtgctatg atttctcctt
    10501 tgtatgtgag gattatcgga gatgatatga cagatgctat gggggttaga caggcaactg
    10561 ctggtgtagt taatattctc agcaacctta tagggggagt tttgattggg ggtcatcagt
    10621 cttcagatgt ttgtaggttt gaatgctttg acctttcttt ttgcactgtt gggtgtggtg
    10681 tttattcgta cttctttgag agatattgag gaacagatgg aggttagtaa aagattagcc
    10741 gcaaaatctt ttggagagca tttcctccat tcaatgaaga tattgtcaag ttttccagcc
    10801 atcatcaaat taatattcat tgcagctatg aaccaagtga ttttaagcat tattatccct
    10861 ttaacgactt tgatgttaat ccatcatcca tttatcttct ttgacactgg gaaatccatt
    10921 gcagcattgt cagtggttat tttttcagga acgattgtgg gaagtttttt gagtggaggt
    10981 atcctaaaaa atattcccat aaaaatgatt gtctactttg aagaaattat gcatctctgt
    11041 attctctttt cttggttgac caatcatttc ctccttttat tggtagttgt cttcttatgc
    11101 gcagttgcag taggaatgat ggggcctcgg attttcaacc ttgtattctc gatggttcca
    11161 gaagaagtca tgggaaccat ccagtcagtg cttggagtat tcaatgttgt tgtaccagga
    11221 attcttagca tgctcatcgt tgccttagcg agtgctacaa acctaaaaat cacagtgctt
    11281 ccacttttta tttttgtatt gactgcctta gcaattgtga aagcaatgaa aatagagtaa
    11341 tagtagtatg aactactgtc tctttttggg tgggagttca ttacccatca gacgtccttg
    11401 ccagtctctg tgtgggcttg ggagttttgt ttatcgagtt tcccttctat gacaagctcc
    11461 gcttccaatg gcgatttaaa ggcaaacaga agtgagtatc gaattccctt gaggagaaag
    11521 aaatgaaagt caatatagca gatcttcatc cgactcaact atatttatca gaaaagaagt
    11581 tgcaagatat tcagatgctt taccagtcgg cagaaacaat ccaagtcgat ccaatcagta
    11641 ttcttgcctt tggagattgt ttgctgatta cagatgggca tcacagggct tatcaggctt
    11701 tattggcagg tcgggatacg atttctgctg agtgggatag agatggtggt gatgaactat
    11761 atcatctcta tgcgcaagct tgcgaggaaa gaaagattta ctctgttttt gatttaaaaa
    11821 atcatatctt acctctttgg atcggcatgg tgagcttttt ttgattgaag tcaaggagaa
    11881 gggagaatgg tttccaattg gggatattac actatctcag gataatctcc ccattgtgat
    11941 tgggaattcc gcttaccaac atcgaggact tggaaaaaag attctaagtg ctttgattga
    12001 attggctcga gtaaaaggat ggaaagaatt gagagtcaag gaaatctaca cctacaatca
    12061 tgcttctagg aggtgtttca agtcgcttgg atttgtggaa aatggagcaa cagaaaaagg
    12121 aaggagtttt atattggaat tagtctaatc ctgccacttt ctccccctta acctttgact
    12181 attccgcaaa attatcgtaa aataaagagt aaatgataaa atgaggtcag agtctgttcg
    12241 ctctgacgat agtagtataa atgaggagaa acgctttgga attagaagta tttgctgggc
    12301 aagaaaaaag tgaactatct atgattgagg tagcgcgtgc tatattagaa cttcgtggtc
    12361 gcgatcatga gatgcatttt agcgatcttg taaacgaaat tcaaaactac cttggaacat
    12421 caaacagcga tatccgcgaa gctttgcctc tgttctacac agagttgaac tttgacggta
    12481 gcttcatctc acttggggac aacaaatggg gtcttcgttc atggtatggt gtggacgaaa
    12541 tcgacgaaga aatcatcgct cttgaagaaa atgacgacga tgaagtagca ccaaaagcta
    12601 agaaaaaacg tgtcaatgcc tttatggatg gtgattcaga tgccattgac tacaatgcag
    12661 atgatccaga agacgaagat gcatacgaag cagatccagc tctttcatac gatgatgaaa
    12721 atccagatga tgaaaaaaat gaagtggaag cttatgatgc agaaatcaac gaaatcgctc
    12781 cagatgactt gggagaagat gtggatctca acgaagacga cgacgagttt tcagatgacg
    12841 acgctgaaac cagcgaggaa taagagttag ctattgacaa ttatcctatt tttaggtatc
    12901 atattgtttg ggcacctctt ttagaggtcg gggctcccta gttcttaggg agctattttt
    12961 gttttttcaa gaagttatct tcttgtattt tatactcaat gaaaatcaaa gagcaagcta
    13021 ggaaactggc cgtaggctgc tcaaaacact gttttgaggt tgtagataag actgacaaag
    13081 tcaggaacac atatctacgg caaggcgacg ttgacgcggt ttgaagagat tttcgaagag
    13141 tattagttgt gaatctggtg cagtcgtccc agattattct tattagtagg gtcttgtttt
    13201 ctatatcccc tcgtagttaa caagaccttg agcattttag aaagaggaat ctatgtctac
    13261 gaaatatatt tttgtaactg gtggtgtggt atcgtctatt gggaaaggga ttgtggcagc
    13321 gagtctaggc cgtctcttga aaaatcgtgg tctcaaagta accattcaaa agtttgaccc
    13381 ttatatcaat attgatccgg gaaccatgag tccttaccag cacggggaag tttttgtgac
    13441 agatgacgga gctgagacag atttggactt gggtcactat gaacgtttca tcgatatcaa
    13501 tctcaacaaa tattccaacg tgacaactgg gaaaatttac agtgaagttc ttcgtaaaga
    13561 acgccgtgga gaataccttg gggcaactgt tcaagtcatt cctcatatca cagatgcttt
    13621 gaaagaaaaa atcaagcgtg ccgctctaac gaccgactct gatgtcatta tcacagaggt
    13681 tggtggaaca gtaggagata tcgagtcctt gccattccta gaggctcttc gtcagatgaa
    13741 ggcagatgtg ggtgcggata atgtcatgta tatccataca accttgcttc cttacctcaa
    13801 ggctgctggt gaaatgaaaa ccaaaccaac ccaacactct gtcaaagaat tgcgtggctt
    13861 gggaatccaa ccaaatatgt tggttattcg tacagaagag ccagctggtc aaggaattaa
    13921 aaataaactg gcccagttct gtgatgtggc accagaagcc gttatcgaat cgttggatgt
    13981 tgaacacctt taccaaattc cactgaactt gcaggcacaa gggatggacc aaattgtttg
    14041 tgatcatttg aaattagacg caccagcagc ggatatgaca gaatggtcag ccatggtgga
    14101 caaggtcatg aacctcaaga aacaagttaa gatttccctt gttggtaagt atgtggagtt
    14161 gcaagatgcc tatatctcag tggtcgaagc cttgaaacac tctggctatg tcaatgatgt
    14221 agaagttaaa atcaattggg tcaatgccaa tgatgtgaca gcagagaatg tagcagaact
    14281 cttgtctgat gcggacggga tcatcgtacc aggtggtttt ggtcaacgtg gtacagaagg
    14341 gaaaatccaa gccatccgct atgcgcgtga aaatgatgtt ccaatgttgg gagtctgctt
    14401 gggaatgcag ttgacatgta tcgagtttgc tcgtcacgtt ttaggtcttg aaggtgccaa
    14461 ttctgcagag cttgcaccag aaacaaaata ccctatcatt gatatcatgc gtgatcagat
    14521 tgatattgag gatatgggtg gaacccttcg tttgggactt tatccgtcta agttgaaacg
    14581 tggctctaag gctgctgctg cttatcacaa tcaagaagtg gtgcaacgcc gtcaccgtca
    14641 ccgttatgag tttaataatg ccttccgtga gcagtttgag gcagcaggtt ttgtcttttc
    14701 aggagtttct ccagacaatc gtttggtaga aatcgtggaa attcctgaaa ataaattctt
    14761 tgtagcttgt cagtatcacc ctgaactgtc aagccgtcca aaccgaccag aagaactcta
    14821 cactgccttt gttactgcag cggttgagaa cagcaattag caaaatcaga acctttgaga
    14881 aaaatctcag aggttttttg catacgatga tattgcaata tatctgaggt agggggcctc
    14941 tgtatgtacc tgctaccgtt gaaatcaata gcgactccct cttgccctgt gctagtgaat
    15001 ggatttatca gtatattgaa atgaaataaa atttgaacaa attaattcgg aaagccaaat
    15061 caatttctag caaagtttta ggaactggat tgtatagtga attgaaataa gatgtgaaca
    15121 tctctatcag aaaagtcaaa ttaatttata gaaatatttt agcagtcaag atgtactgtt
    15181 atagattcaa tacattatac ttttttaatt taatccacta tagtaaaatg aaataagaac
    15241 aggacaaatc gatcaggaca gtcaaatcga tttctaacaa tgttttagaa atagaggtgt
    15301 actattctag tttcaatata ctatatatct gcagaatact ctttcagttt cattcagcct
    15361 agtcttgctt aggaaaaagt aaaaagccat ccaattatga tggatagctt cttggttctt
    15421 agatttgttc tgcaaaaacc ttttcagcaa ggttcatagc gtggtctgat acacgagtgt
    15481 agtgtgagat gatgtcgata aagttgaccc cagcttgtgt tgaacattcg cctttgttga
    15541 ggcgtttgat gtgggttttt ctgagaacac gttctatctt attgattgct tcatgacgtt
    15601 ctacaagact gcgtgctttt tcaatatcat tgttttccac actatccaga gcatctttga
    15661 taaagtcact agtttggcgg taaacttcct ctaattcttt caaggcggca tcagaaaatt
    15721 caacattttt ccgttgaaga tagtcagtca gattgagtag agcctccgtg tggtctccaa
    15781 tccgttccaa atcacgggag gaatcaagga tattggtaag cacttcactt tctttttggc
    15841 tgagagcttc gcttgaaagg gcaatgagat aacgtgttaa ttgctcatcg atggtgttaa
    15901 ttgcttcttc ggttttatgc cctttttcag caactttttc atccaagtca atgatgtact
    15961 tataggaaag gtcaaaggct ttagcagcgt agtttcctaa gtgcaagagc tctttcttag
    16021 catttcctag agcgatagat ggggcctgtt tgatgaaatg ttcatcaaga tataagggtt
    16081 cgtatttgac aacctcgtcc tctccaggaa taatcttggt tacaaagtaa gccagagctc
    16141 cgataaatgg aaattggaca atggtgttgg taatattaaa ggttccgtga gcaaaggcga
    16201 tggtcatttc cggtgctaga tttagcgtag cttcaaacca atgaatcagg acagtaaaag
    16261 gaactagaaa aataacgcag acgactgttc cgataacgtt gaaggcaaca tgagctcctg
    16321 ctacccgttt agctgcaata ttagccccta aagaggcaat gatggctgta atggttatcc
    16381 cgatattgtc accaaataga actggcaaag ctccctgtag gtcaattaga ttgccggcgt
    16441 agaggttttg taaaatccca atggtagccg aagaagcttg aattagcaag gtcaagccgg
    16501 taccgacaaa gacacccaaa acaggattct tacttagctc aatcatatag tccttaaaga
    16561 cctgtaaatc cttgagtgga gccattgcgc cgctcatgag attgagggca aaaaagatac
    16621 caccgacacc aaagaggatg cgtccgatat tattgactgt ccgatttttt gtaaaaaaga
    16681 gacagacggc accgataaag agcataggta gggcatagtt acctaattta aaaccgatga
    16741 gaaaggatgt gacagttgtc ccaatattag cacccatgac aatcccgata gcctgacgta
    16801 aggttaagag accggcactg accaggccga ctgtgataac tgttacacca gaactagact
    16861 gaattagagc agtcatccca ataccaacca gaactccaaa gaaaggatta ctagtatatt
    16921 tgtcaatgta aaaacgaagg cgatctccag cagcttgttg caaaccgtct cccatggtct
    16981 tgatgctata taagaatagc cccagaccac ctaaaaagtg aaataaaatt tcctgccaat
    17041 taatggacat ttctttttcc tccgaaaaat aatcgcggaa tatcttctat tctattttaa
    17101 aggataaaag taaatctaac aagtgttaat gtcaagtttg taaaagaaaa ttataattga
    17161 taagtgtatt atttttaaga gtttttaacc ttattttaga tttgtgcaaa cagttattgt
    17221 tttttgtcta aaaatgtttt aggataaaaa tgtgattatc atggttctag agtttgataa
    17281 aaaactacag aatataaagc gctttcttga aaacaacaaa atcaatcttt taggaggaga
    17341 aaatgaagaa tccatttttt gaaagacgtt gtcgttacag tattcgtaag ttatcagtag
    17401 gagcctgctc gctgatgatt ggtgctgttt tatttgctgg tccagccttg gctgaagaaa
    17461 ctgcagttcc tgaaaatagc ggagctaata cagagcttgt ttcaggagag agtgagcatt
    17521 cgaccaatga agctgataag cagaatgaag gggaacatgc tagagaaaac aagctagaaa
    17581 aggcagaagg agtagcgata gcatctgaaa ctgcttcgcc agcaagcaat gaagctgcaa
    17641 ctactgaaac tgcagaagca gctagcgcag ctaaaccaga ggaaaaagca agtgaggtgg
    17701 ttgcagaaac accatctgca gaagcaaaac ctaagtctga caaggaaaca gaagcaaagc
    17761 ccgaagcaac taaccaaggg gatgagtcta aaccagcagc agaagctaat aagactgaaa
    17821 aagaagtcca gccagatgtc cctaaaaata cagaaaaaac attaaaacca aaggaaatca
    17881 aatttaattc atgggaagaa ttgttaaaat gggaaccagg tgctcgtgaa gatgatgcta
    17941 ttaaccgcgg atctgttgtc ctcgcttcac gtcggacagg tcatttagtc aatgaaaaag
    18001 ctagcaagga agcaaaagtt caagccttat caaacaccaa ttctaaagca aaagaccatg
    18061 cttctgttgg tggagaagag ttcaaggcct atgcttttga ctattggcaa tatctagatt
    18121 caatggtctt ctgggaaggt ctcgtaccaa ctcctgacgt tattgatgca ggtcaccgta
    18181 acggggttcc tgtatacggt acactcttct tcaactggtc taatagtatt gcagatcaag
    18241 aaagatttgc tgaagctttg aagcaagacg cagatggtag cttcccaatt gcccgtaaat
    18301 tggtagacat ggccaagtat tatggctatg atggctattt catcaaccaa gaaacaactg
    18361 gagatttggt taaacctctt ggagaaaaga tgcgccagtt tatgctctat agcaaggaat
    18421 atgctgctaa ggtaaaccat ccaatcaagt attcttggta cgatgccatg acctataact
    18481 atggacgtta ccatcaagat ggtttgggag aatacaacta ccaattcatg caaccagaag
    18541 gagataaggt tccggcagat aacttctttg ctaactttaa ctgggataag gctaaaaatg
    18601 attacactat tgcaactgcc aactggattg gtcgtaatcc ttatgatgta tttgcaggtt
    18661 tggaattgca acagggtggt tcctacaaga caaaggttaa gtggaatgac attttagacg
    18721 aaaatgggaa attgcgcctt tctcttggtt tatttgcccc agataccatt acaagtttag
    18781 gaaaaactgg tgaagattat cataaaaatg aagatatctt ctttacaggt tatcaaggag
    18841 accctactgg ccaaaaacca ggtgacaaag attggtatgg tattgctaac ctagttgcgg
    18901 accgtacgcc agcggtaggt aatactttta ctacttcttt taatacaggt catggtaaaa
    18961 aatggttcgt agatggtaag gtttctaagg attctgagtg gaattatcgt tcagtatcag
    19021 gtgttcttcc aacatggcgc tggtggcaga cttcaacagg ggaaaaactt cgtgcagaat
    19081 atgattttac agatgcctat aatggcggaa attcccttaa attctctggt gatgtagccg
    19141 gtaagacaga tcaggatgtg agactttatt ctactaagtt agaagtaact gagaagacca
    19201 aacttcgtgt tgcccacaag ggaggaaaag gttctaaagt ttatatggca ttctctacaa
    19261 ctccagacta caaattcgat gatgcagatg catggaaaga gctaaccctt tctgacaact
    19321 ggacaaatga agaatttgat ctcagctcac tagcaggtaa aaccatctat gcagtcaaac
    19381 tatttttcga gcatgaaggt gctgtaaaag attatcagtt caacctcgga caattaacta
    19441 tctcggacaa tcaccaagag ccacaatcgc cgacaagctt ttctgtagtg aaacaatctc
    19501 ttaaaaatgc ccaagaagcg gaagcagttg tgcaatttaa aggcaacaag gatgcagatt
    19561 tctatgaagt ttatgaaaaa gatggagaca gctggaaatt actaactggc tcatcttcta
    19621 caactattta tctaccaaaa gttagccgct cagcaagtgc tcagggtaca actcaagaac
    19681 tgaaggttgt agcagtcggt aaaaatggag ttcgttcaga agctgcaacc acaacctttg
    19741 attggggtat gactgtaaaa gataccagcc taccaaaacc actagctgaa aatatcgttc
    19801 caggtgcaac agttattgat agtactttcc ctaagactga aggtggagaa ggtattgaag
    19861 gtatgttgaa cggtaccatt actagcttgt cagataaatg gtcttcagct cagttgagtg
    19921 gtagtgtgga tattcgtttg accaagccac gtaccgttgt tagatgggtc atggatcatg
    19981 caggagctgg tggtgagtct gttaacgatg gcttgatgaa cactaaagac tttgaccttt
    20041 attataaaga tgcagatggt gagtggaagc tagctaagga agtccgtggt aacaaagcac
    20101 acgtgacaga tatcactctt gataaaccaa tcactgctca agactggcgc ttgaatgttg
    20161 tcacttctga caatggaact ccatggaagg ctattcgtat ctataactgg aaaatgtatg
    20221 aaaagcttga tactgagagt gtcaatattc cgatggccaa ggctgcagcc cgttctctag
    20281 gcaataacaa ggtacaagtt ggctttgcag atgtaccggc tggagcaact attaccgttt
    20341 atgataatcc aaattctcaa actccgctcg caaccttgaa gagcgaagtt ggaggagacc
    20401 tagcaagtgc accattggat ttgacaaatc aatctggtct tctttattat cgtacccagt
    20461 tgccaggcaa ggaaattagt aatgtcctag cagtttccgt tccaaaagat gacagaagaa
    20521 tcaagtcagt cagcctagaa acaggaccta agaaaacaag ctacgccgaa ggggaggatt
    20581 tggaccttag aggtggtgtt cttcgagttc agtatgaagg aggaactgag gacgaactca
    20641 ttcgcctaac tcacgcaggt gtatcagtat caggttttga tacgcatcat aagggagaac
    20701 agaatcttac tctccaatat ttgggacaac cagtaaatgc taatttgtca gtgactgtca
    20761 ctggccaaga tgaagcaagt ccgaaaacta ttttgggaat tgaagtaagt caggaaccga
    20821 aaaaagatta cctagttggt gatagcttag acttgtctga aggacgcttt gcagtggctt
    20881 atagcaatga caccatggaa gaacattcct ttactgatga gggagttgaa atttctggtt
    20941 acgatgctca aaagactggt cgtcaaacct tgacgcttcg ttaccaaggt catgaagtca
    21001 actttgatgt tttggtatct ccaaaagcag cattgaacga tgagtacctc aaacaaaaat
    21061 tagcagaggt tgaagctgct aagaacaagg tggtctataa ctttgcttca ccagaagtaa
    21121 aagaagcttt cttgaaagca attgaagcgg ccgaacaagt gttgaaagac catgaaacta
    21181 gcacccaaga tcaagtcaat gaccgactta ataaattgac agaagctcat aaagctctga
    21241 atggtcaaga gaaatttaag gaagaaaaga cagagcttga tcgtttaaca ggtgaggttc
    21301 aagaactctt ggctgccaaa ccaaaccatc cttcaggttc tgccctagct ccgcttcttg
    21361 agaaaaacaa ggccttggtt gaaaaagtag atttgagtcc agaagagctt gcaacagcga
    21421 aacagagtct aaaagatctg gttgctttat tgaaagaaga caagccagca gtcttttctg
    21481 atagtaaaac aggtgttgaa gtacacttct caaataaaga gaagactgtc atcaagggtt
    21541 tgaaagtaga gcgtgttcaa gcaagtgctg aagagaagaa atactttgct ggagaagatg
    21601 ctcatgtctt tgaaatagaa ggtttggatg aaaaaggtca agatgttgat ctctcttacg
    21661 cttctattgt gaaaatccca attgaaaaag ataagaaagt taagaaagta tttttcttac
    21721 ctgaaggcaa agaggcagta gaattggctt ttgaacaaac ggatagtcat gttatcttta
    21781 cagcaccaca ctttactcat tatgcctttg tttatgaatc tgctgaaaaa ccacaacctg
    21841 ctaaaccagc accacaaaac aaagtccttc caaaacctac ttatcaaccg gcttctgatc
    21901 aacaaaaggc tcctaaattg gaagttcaag aggaaaaggt tgcctttcat cgtcaagagc
    21961 atgaaaatgc tgagatgcta gttggggaac aacgagtcat catacaggga cgagatggac
    22021 tgttaagaca tgtctttgaa gttgatgaaa acggtcagcg tcgtcttcgt tcaacagaag
    22081 tcatccaaga agcgattcca gaaattgttg aaattggaac aaaagtaaaa acagtaccag
    22141 cagtagtagc tacacaggaa aaaccagctc aaaatacagc agttaaatca gaagaagcaa
    22201 gcaaacaatt gccaaataca ggaacagctg atgctaatga agccctaata gcagtcttag
    22261 ccagccttgg tcttgctagt ttagccttga ccttgagacg gaaaagagaa gataaagatt
    22321 aaatatcgaa aaatcttgtg aaatctttcc ttatatttcc aaagtgtgat ataatagttt
    22381 cgaataaaat aaataaagga gtttttgtaa catggcaaaa cttactgtta aagacgttga
    22441 cttgaaaggt aaaaaagtcc tcgttcgtgt tgacttcaac gtaccattga aagatggcgt
    22501 aatcactaac gataaccgta tcacagcagc tcttccaact attaagtaca tcatcgaaca
    22561 aggtggacgt gcaattcttt tctctcacct tggacgtgtg aaagaagaag ctgataaagc
    22621 tggcaaatca cttgctcctg tagcagctga cttggcagca aaacttggtc aagatgttgt
    22681 tttcccaggt gtcactcgtg gtgctgaatt ggaagcggca atcaacgctc ttgaagatgg
    22741 acaagttctc ttggttgaaa acactcgtta cgaagatgtt gacggcaaga aagaatctaa
    22801 aaacgatcct gaacttggta aatactgggc atcacttgga gatggtatct tcgtaaacga
    22861 tgcattcggt acagctcacc gtgcacacgc atctaacgtt ggtatctcag caaacgttga
    22921 aaaagcagtt gctggtttcc ttcttgaaaa cgaaattgcc tacatccaag aagcagttga
    22981 aactccagaa cgtccattcg tggctatcct tggtggttca aaagtttcag acaagatcgg
    23041 tgttatcgaa aacttgcttg aaaaagctga taaagtcctt atcggtggtg ggatgactta
    23101 cacattctac aaagcacaag gtatcgaaat cggtaactca cttgtagaag aagacaaatt
    23161 ggatgttgcg aaagctcttc ttgaaaaagc aaatggtaaa ttgatcttgc cagttgactc
    23221 aaaagaagct aacgcatttg ctggttacac tgaagtgcgt gacactgaag gtgaagcagt
    23281 ttctgaaggc ttccttggtc ttgacatcgg tccaaaatct atcgccaaat ttgacgaagc
    23341 tttgactggt gccaaaacag ttgtatggaa cggacctatg ggtgtatttg aaaacccaga
    23401 tttccaagct ggtacaatcg gtgtgatgga cgctatcgtg aaacaaccag gagttaaatc
    23461 aatcatcggt ggtggtgact cagctgccgc agcgattaac cttggccgtg cagacaagtt
    23521 ctcatggatt agtacgggtg gtggagcatc aatggaactt cttgaaggta aggttcttcc
    23581 aggacttgca gccttgacag aaaaataaga ttttataaac aaatcaaaga agagagggat
    23641 gaaagttcct cttttctttt gcttaaaata aaaacgcttc ctctcaacta ttactcataa
    23701 aaatcaccga tttatgataa aatggaaata gaaagttgag attatgagtt attttaaaaa
    23761 atataaattc gataaatccc agttcaaact tggtatgcga acctttaaaa caggtattgc
    23821 tgtttttcta gttctcttga tttttggctt ttttggctgg aaaggtcttc aaattggtgc
    23881 tttgacagcc gtttttagcc tgagggagag ttttgatgag agtgttcatt ttgggacttc
    23941 gcgtattcta ggaaatagta tcggtggact ctatgccttg gtcttcttct tattaaatac
    24001 ttttttccac gaagcctttt gggtgacctt ggtagttgtt ccaatctgca ccatgttaac
    24061 cattatgaca aatgtagcca tgaataacaa agcaggggtt attggtggtg tagcagctat
    24121 gttaatcatt accctatcaa ttccaagtgg tgagacaatt ttgtacgtgt ttgtgcgtgt
    24181 attagaaacg tttatgggag tttttgtcgc aattatcgta aattacgata ttgatcgtat
    24241 tcgtctcttt ttagagaaaa aagaaaaata atgttacatt ttataacatt atcaattgac
    24301 gtttgtcttt ttttagacta taatagacag aaagaaggaa attgtaaatg aaggaaaaag
    24361 aatttcgccg aaatatggct gtttttccta tcggcagtgt tatgaagttg accgatttat
    24421 cggcgcgtca gattcgttat tatgaagatc aagagttgat caagcccgat cgaaacgaag
    24481 gaaatcgtcg catgtattcc ttgaatgaca tggatcgtct gcttgaaatc aaagattata
    24541 tctctgaagg ttataatatc gctgccatta agaaaaaata tgctgaacgt gaagcgaaat
    24601 ccaagaaagc ggttagtcag actgaagtac gtcgtgcact tcacaatgaa ctcctccaac
    24661 aggggcgttt tgcttcagta cagtcacctt ttggtcgcgg ttaggcaacc gcaagtagtc
    24721 atagattaag gagaaaactt atgccaatca cagctgcaga tattcgtcgt gaagtcaagg
    24781 aaaaaaatgt tacctttatt cgtcttatgt tctcagatat tttgggaacc atgaaaaacg
    24841 tcgaaattcc tgctacagat gaacagttag ataaggtctt gtcgaacaag gttatgtttg
    24901 atggatcttc tattgaaggt tttgtacgta tcaatgagtc ggatatgtac ttgtacccgg
    24961 acttggatac atggacagtc ttcccttggg gagatgaaaa tggaagtgtt gcaggtctga
    25021 tctgtgatgt ctatacaaca gaaggtgaac catttgcggg tgaccctcgt ggtaatttga
    25081 aacgagctct tcgtcacatg gaagaagttg gattcaaatc cttcaacctt ggtccagagc
    25141 cagaattctt cctatttaag ttggatgaaa atggggaccc aacacttgaa gtgaatgaca
    25201 agggtggcta ctttgatttg gcacctactg accttgcgga caacacacgt cgtgagattg
    25261 tgaatgtctt gaccaaaatg ggatttgaag tagaagcgag tcaccacgag gttgcggttg
    25321 gacagcatga gattgacttt aagtacgatg aagttctccg tgcttgtgat aagattcaaa
    25381 tctttaagct tgttgttaaa accattgctc gcaaacacgg actttacgca acatttatgg
    25441 cgaagccaaa atttggtatt gctggatcag gtatgcactg taatatgtcc ttgtttgatg
    25501 cagaaggaaa taacgccttc tttgatccaa atgatccaaa aggaatgcag ttgtcagaaa
    25561 cagcttacca tttcctaggc ggtttgatca agcatgctta caactatact gccatcatga
    25621 acccaacagt taactcatac aaacgtttgg ttccaggtta tgaagcgcct gtttacattg
    25681 cttgggctgg tcgtaaccgt tcgccacttg tgcgcgtacc tgcttcacgt ggtatgggaa
    25741 ctcgtcttga gttgcgttca gtggatccaa tggcgaaccc ttacattgct atggctgttc
    25801 ttttggaagt tggtttgtat ggtattgaaa ataaaatcga agcaccagct cctatcgaag
    25861 aaaatatcta catcatgaca gcagaagagc gcaaggaagc tggtattaca gaccttccat
    25921 caactcttca caacgctttg aaagctttga cagaagatga agtggttaaa gctgctctcg
    25981 gagatcacat ctacactagc ttccttgaag ccaaacgaat cgaatgggca agttatgcaa
    26041 ccttcgtttc acaatgggaa attgataatt atttagacct ttactaatac taatatagaa
    26101 gaaagattgc ctgtgggtaa acagtcacac agcagtctaa gccatcaaat acctataacc
    26161 cttaaaatag cgatttcggt cgctatttat ttttcgaaaa atcctcttga ctcttttgcg
    26221 aattagattt atcatcagac gtgtagaaga aaatcaagga gtcactatgg aaaaattcaa
    26281 tttcaaaaac aatatcgggc aagaaaacaa gttacttcaa atcgaaatct acaagtttac
    26341 taacttttgc aagcttcaaa attacacatc tgtaaatatt ttttcgaaag atatatttga
    26401 agccatagta aattgagact agaatagtac actacatctg ctaaaaattt ctagaaatta
    26461 atttaacttt cctaatcgat ttgtttacat cttatttcaa tctactatat tatctcaata
    26521 aatgatgatg gcgactgttt tgtttgtgct tgtcgatttt tgaatcctga tcgagcggaa
    26581 gaatatttct gccgaggttg tcaaggggaa aatcctgaag atattgaatt ttatgatgaa
    26641 caattacagg cagaaaaggt ggaggctttg aatattcgat tggaagtaaa aaattgaatt
    26701 atctacaatc tcatcaacaa taaacctatt tcaaccccat tatctatagg cgtattttta
    26761 cgccttttta tatacttgaa gcacataaga aacattatgg gaagtttgct gatggaagta
    26821 ctcaagaaat tgatgttcct tatgatattc ctgatacttg ggagtgggtg aggataaaat
    26881 caatttattg gaattttggg caaaataagc cagagaaatc ctttaggtat atagatacgt
    26941 ctagtattga tagaaaaaag aacataatca actacaaaaa tctacaatat ctttcacctg
    27001 aacaagcgcc ttcccgtgcc agaaaattag tttcgcagaa tagtgtctta ttttcaacag
    27061 ttagaccata tctaaaaaat attgctgtag ttagagaact taaagagtat ttgatagcta
    27121 gtacagcatt tattgttttg gatactttac ttaacgaaac atatttgaaa tattatttat
    27181 tatcagataa ttttatcaat cgtgttaata ataaatctac tggaacaagt tatcctgcaa
    27241 tcaatgatta taattttaat ctattattaa tt
//
LOCUS       DAVBEO010000028        25876 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 009
            SAMEA1678075-rid20185393.denovo.028, whole genome shotgun sequence.
ACCESSION   DAVBEO010000028 DAVBEO010000000
VERSION     DAVBEO010000028.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678075
            Sequence Read Archive: ERR226392
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 25876)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25876)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980207.1
            Genome Coverage       :: 150x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:50:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 72 of 147
            Pseudo Genes (incomplete)         :: 72 of 147
            Pseudo Genes (internal stop)      :: 42 of 147
            Pseudo Genes (multiple problems)  :: 32 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25876
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678075-rid20185393.denovo.028"
                     /strain="KS 009"
                     /db_xref="taxon:1313"
     gene            complement(146..397)
                     /locus_tag="VQ543_001201"
     CDS             complement(146..397)
                     /locus_tag="VQ543_001201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000604885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2611924.1"
                     /translation="MPKTKTLAELADVILWSFDFANDHAHAFFMDNVEWSHADSYFLS
                     FVSDDVEERYIENVYLDSLSVKQKFKFIFDFGDEWRFEC"
     gene            complement(687..2567)
                     /locus_tag="VQ543_001202"
     CDS             complement(687..2567)
                     /locus_tag="VQ543_001202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-N-acetylhexosaminidase"
                     /protein_id="HET2611925.1"
                     /translation="MVRFTGLSPKQTQAIEVLKGHISLPDVEVAVTQSDQASISIQGE
                     EGHYQLTYRKPHQLYRALSLLVTVLAEADKVEIEEQAAYEDLAYMVDCSRNAVLNVAS
                     AKQMIEVLALMGYSTFELYMEDTYQIEGQPYFGYFRGAYSAEELQEIEAYAQQFDMTF
                     VPCIQTLAHLSAFVKWGVKEVQELRDVEDILLIGEEKVYDLIDGMFATLSKLKTRKVN
                     IGMDEAHLVGLGRYLILNGVVDRSLLMCQHLERVLDIADKYGFHCQMWSDMFFKLMSA
                     DGQYDRDVEIPEETRVYLDRLKDRVTLVYWDYYQDSEEKYNRNFRNHHKISHDLAFAG
                     GAWKWIGFTPHNHFSRLVAIEANKACRANQIKEVIVTGWGDNGGETAQFSILPSLQIW
                     AELSYRNDLDGLSAHFKTNTGLTVEDFMQIDLANLLPDLPGNLSGINPNRYVFYQDIL
                     CPILDQHMTPEQDKPHFAQAAETLANIKEKAGNYAYLFETQAQLNAILSSKVDVGRRI
                     RQAYQADDKESLQQIARQELPELRSQIEDFHALFSHQWLKENKVFGLDTVDIRMGGLL
                     QRIKRAESRIEVYLAGQLDRIDELEVEILPFTDFYADKDFAATTANQWHTIATASTIY
                     TT"
     gene            complement(2561..3430)
                     /locus_tag="VQ543_001203"
     CDS             complement(2561..3430)
                     /locus_tag="VQ543_001203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HET2611926.1"
                     /translation="MTIATIDIGGTGIKFASLTPDGKILDKTSISTPENLEDLLAWLD
                     QRLSEQDYSGIAMSVPGAVNQETGVIDGFSAVPYIHGFSWYEALSSYQLPVHLENDAN
                     CVGLSELLAHPDLENAACVVIGTGIGGAMIINGRLHRGRHGLGGEFGYMTTLAPAEKL
                     NNWSQLASTGNMVRYVIEKSGHTDWDGRKIYQEAAAGNILCQEAIERMNRNLAQGLLN
                     IQYLIDPDVISLGGSISQNPDFIQDVKKAVDNFVDTYEEYTVAPVIQACTYHADANLY
                     GALVNWLQEEKQW"
     gene            complement(3514..6159)
                     /locus_tag="VQ543_001204"
     CDS             complement(3514..6159)
                     /locus_tag="VQ543_001204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000432759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HET2611927.1"
                     /translation="MENVVVHIISHSHWDREWYLPFESHRMQLVELFDNLFDLFENDP
                     EFKSFHLDGQTIVLDDYLQIRPENRDKVQRYIDEGKLKIGPFYILQDDYLISSEANVR
                     NTLIGQQEAAKWGKSTQIGYFPDTFGNMGQAPQILQKSGIHVAAFGRGVKPIGFDNQV
                     LEDERFTSQFSEMYWQGVDGSRVLGILFANWYSNGNEIPVDKDEALTFWKQKLSDVRA
                     YASTNQWLMMNGCDHQPVQKNLSEAIRVANELFPDVIFVHSSFDEYVQAVEGALPEHL
                     STVTGELTSQETDGWYTLANTSSSRIYLKQAFQENSNLLEQVVEPLTIITGGHNHKDQ
                     LTYAWKTLLQNAPHDSICGCSVDEVHREMETRFAKVNQVGNFVKSNLLNEWKGKIATD
                     KAQSDYLFTVINTGLHDKVDTVSTVIDVATCDFKELHPTEGYKKMAALILPSYRVEDL
                     DGRPVEATIEDLGANFEYDLPKDKFRQARIARQVRVTIPVHLAPLSWTTFQLLEGKQE
                     HREGIYQNGVIDTPFVTVSVDDNITVYDKTTHEAYEDFIRFEDRGDIGNEYIYFQPKG
                     TEPIFAELKGHEVLENTDRYAKILLKHELTVPVSADEKLEEEQQGIIEFMKREAGRSE
                     ELTNIPLETELIVFVDNPQIRFKTRFTNTAKDHRIRLLVKTHNTRPSNDSESIYEVVT
                     RPNKPAASWENPENPQHQQAFVSLYDDEKGVTVSNKGLNEYEILGDNTIAVTILRASG
                     ELGDWGYFPTPEAQCLREFEVEFALECHQAQERFSAFRRAKALQTPFTSLQLARQEGS
                     VVATGSLLSHSVLSIPQVCPTAFKVAENEEGYVFRYYNMSQENVHISEHQQTILDLLE
                     RPYPVHSGPLDPQEIRTEFIKKEEI"
     gene            complement(6250..7530)
                     /locus_tag="VQ543_001205"
     CDS             complement(6250..7530)
                     /locus_tag="VQ543_001205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 125 protein"
                     /protein_id="HET2611928.1"
                     /translation="MIYSKEIVREWLDEVAERAKDHPEWVDVFERCYTDTLDNTVEIL
                     EDGSTFVLTGDIPAMWLRDSTAQLRPYLHVAKRDALLRQTIAGLVKRQMTLVLKDPYA
                     NSFNIEENWKGHHETDHTDLNGWIWERKYEVDSLCYPLQLAYLLWKETGETSQFDETF
                     VAATKEILHLWTVEQDHKNSPYRFVRDTDRKEDTLVNDGFGPDFAVTGMTWSAFRPSD
                     DCCQYSYLIPSNMFAVVVLGYVQEIFAALNLADSQSVIADAKRLQDEIQEGIENYAYT
                     TNSKGEKIYAFEVDGLGNASIMDDPNVPSLLAAPYLGYCSIDDEVYQATRRTILSSEN
                     PYFYQGEYASGLGSSHTFYRYIWPIALSIQGLTTRDKAEKKFLLDQLVACDGGTGVMH
                     ESFHVDDPTLYSREWFSWANMMFCELVLDYLDIR"
     gene            7701..9785
                     /locus_tag="VQ543_001206"
     CDS             7701..9785
                     /locus_tag="VQ543_001206"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000803403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GH92 family glycosyl hydrolase"
                     /protein_id="HET2611929.1"
                     /translation="MKPLLETIDTRFGTASKHAFSRGNTLPYTGVPFGMNYFVPQTSD
                     QDGSWFFDPHLPIFQGIRLTHQPSPWIGDYSWLLLTPVTSQLGGDSLFHRQSSYDIDK
                     ACFQPHYLKLFSLRYQIETQLTPTCYGASIRLNQKQGKALSLYLHAADELTVEQVDKR
                     TLALRQEGKTETNKNSLTMFTALQMNTDILAISQEAGDWRIDLASSQTEMQLATSFIS
                     PSQALINLPQEDFDSCKTSAQADWENLLHRFDIIETGEADRTFFDHCLYRLFLFPQTF
                     YEVDESGKAIHMDLATGTVKPGVLFSNNGFWDTFRTTFPLFALIIPEHYQRFLEGFLN
                     SYRDTGFLPKWLAPDERGMMPGTLLDGIIADSACKDMAPDLEGELFQAMLETASKADP
                     LGINGRHGLAQYQELGYLSTDHHESVSHTLDYAYSDFCIASCAKKLENIEIAETYKAA
                     SQNYRQLFDAETGYMRARDNQGNFHPDFSPYSWGRDYAECSAIQATLGVLHDIPGLIQ
                     LMGGKETFSNYLLKACQDAPLFETTGYGYEIHEMSEMATAPFGQIAISNQPSFHIPYL
                     FRYSDYPDYTALLIKTLRQKAFHPSWEAYPGDEDNGSLSAWYIWSALGFYPTCPGKPS
                     YDLGIPLFDHLRVYLAKENKWLDIHTEQNHSHFNFVKECRLDKTLVSTIQHQDLLKAE
                     QLTFTLSWLPNH"
     gene            complement(9825..11504)
                     /locus_tag="VQ543_001207"
     CDS             complement(9825..11504)
                     /locus_tag="VQ543_001207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000721501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-L-fucosidase"
                     /protein_id="HET2611930.1"
                     /translation="MKKIKPHGPLPSQTQLAYLGDELAAFIHFGPNTFYDQEWGTGQE
                     DPERFNPSQLDAREWVRVLKETGFKKLILVVKHHDGFVLYPTAHTDYSVKVSPWRRGK
                     GDLLLEVSQAATEFDMDMGVYLSPWDAHSPLYHVDREADYNAYYLAQLKEILSNPNYG
                     NAGKFAEVWMDGARGEGAQKVNYEFEKWFETIRDLQGDCLIFSTEGTSIRWIGNERGY
                     AGDPLWQKVNLDKLGTEAELNYLQHGDPSGTIFSIGEADVSIRPGWFYHEDQDPKSLE
                     ELVEIYFHSVGRGTPLLLNIPPNQAGLFDAKDIERLYEFATYRNELYKEDLALGAEVS
                     GPALSADFDCRHLTDGLETSSWASDADLPIQLELDLGSPKTFDVIELREDLKLGQRIA
                     AFHVQVEVDGVWQEFGRGFTVGHKRLLRGPLVEAQKVRVMITEAQSIPVLTKISLYKT
                     PGLSKKEVVQELAFAEKSLAVAKGETLHFRIERSESSSSLEAKISIQPGTGVHGVAYQ
                     DEIYVLAFQAGETEKRLTLPTLYFAGDKTLDFYLNLTVDGQLVDQLQVQVS"
     gene            12259..13488
                     /gene="arcA"
                     /locus_tag="VQ543_001208"
     CDS             12259..13488
                     /gene="arcA"
                     /locus_tag="VQ543_001208"
                     /EC_number="3.5.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000094613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine deiminase"
                     /protein_id="HET2611931.1"
                     /translation="MSSHPIQVFSEIGKLKKVMLHRPGKELENLLPDYLERLLFDDIP
                     FLEDAQKEHDAFAQALRDEGIEVLYLEQLAAESLTSPEIRDQFIEEYLDEANIRDRQT
                     KVAIRELLHGIKDNQELVEKTMAGIQKVELPEIPDEAKDLTDLVESDYPFAIDPMPNL
                     YFTRDPFATIGNAVSLNHMFADTRNRETLYGKYIFKYHPIYGGKVDLVYNREEDTRIE
                     GGDELILSKDVLAVGISQRTDAASIEKLLVNIFKKNVGFKKVLAFEFANNRKFMHLDT
                     VFTMVDYDKFTIHPEIEGNLHVYSVTYENEKLKIVEEKGDLAELLAQNLGVEKVHLIR
                     CGGGNIVAAAREQWNDGSNTLTIAPGVVVVYDRNTVTNKILEEYGLRLIKIRGSELVR
                     GRGGPRCMSMPFEREEV"
     gene            13546..14562
                     /gene="argF"
                     /locus_tag="VQ543_001209"
     CDS             13546..14562
                     /gene="argF"
                     /locus_tag="VQ543_001209"
                     /EC_number="2.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003073325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine carbamoyltransferase"
                     /protein_id="HET2611932.1"
                     /translation="MTNSVFQGRSFLAEKDFTRAELEYLIGLSAHLKDLKKRNIQHHY
                     LAGKNIALLFEKTSTRTRAAFTTAAIDLGAHPEYLGANDIQLGKKESTEDTAKVLGRM
                     FDGIEFRGFSQRMVEELAEFSGVPVWNGLTDEWHPTQMLADYLTVQENFGRLEGLTLV
                     YCGDGRNNVANSLLVTGAILGVNVHIFSPKELFPEKEIVELAEGFAKESGAHVLITED
                     ADEAVKDADVLYTDVWVSMGEEDKFAERVALLKPYQVNMDLVKKAGNENLIFLHCLPA
                     FHDTHTVYGKDVAEKFGVEEMEVTDEVFRSKYARHFDQAENRMHTIKAVMAATLGNLY
                     IPKV"
     gene            14727..15674
                     /gene="arcC"
                     /locus_tag="VQ543_001210"
     CDS             14727..15674
                     /gene="arcC"
                     /locus_tag="VQ543_001210"
                     /EC_number="2.7.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003025409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamate kinase"
                     /protein_id="HET2611933.1"
                     /translation="MANRKIVVALGGNAILSSDPSAKAQQEALVETAKHLVKLIKNGD
                     DLIITHGNGPQVGNLLLQHLASDSEKNPAFPLDSLVAMTEGSIGFWLKNALQNALLDE
                     GIEKNVASVVTQVIVDKNDPAFVNLSKPIGPFYSEEEAKAEAEKSGATFKEDAGRGWR
                     KVVASPKPVDIKEIETIRTLLNNGQVVVAAGGGGIPVVKENNGHLTGVEAVIDKDFAS
                     QRLAELVDADLFIVLTGVDYVFVNYNKPNQEKLEHVNVAQLEEYIKQDQFAPGSMLPK
                     VEAAIAFVNGRPEGKAVITSLENLGALIESESGTIIEKG"
     gene            15883..17394
                     /locus_tag="VQ543_001211"
     CDS             15883..17394
                     /locus_tag="VQ543_001211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004191872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcC family protein"
                     /protein_id="HET2611934.1"
                     /translation="MSEKAKKGFKMPSSYTVLLIIIAIMAVLTWFIPAGAFIEGIYEA
                     QPQNPQGIWDVLMAPIRAMLGTHPEEGSLIKETSAAIDVAFFILMVGGFLGIVNKTGA
                     LDVGIASIVKKYKGREKMLILVLMPLFALGGTTYGMGEETMAFYPLLVPVMMAVGFDS
                     LTGVAIILLGSQIGCLASTLNPFATGIASATAGVGTGDGIVLRLIFWVTLTALSTWFV
                     YRYADKIQKDPTKSLVYSTRKEDLKHFNVEESSSVESTLSSKQKSVLFLFVLTFILMV
                     LSFIPWTDLGVTIFDDFNTWLTGLPVIGNIVGSSTSALGTWYFPEGAMLFAFMGILIG
                     VIYGLKEDKIISSFMNGAADLLSVALIVAIARGIQVIMNDGMITDTILNWGKEGLSGL
                     SSQVFIVVTYIFYLPMSFLIPSSSGLASATMGIMAPLGEFVNVRPSLIITAYQSASGV
                     LNLIAPTSGIVMGALALGRINIGTWWKFMGKLVVAIIVVTIALLLLGTFLPFL"
     gene            17416..18747
                     /locus_tag="VQ543_001212"
     CDS             17416..18747
                     /locus_tag="VQ543_001212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000686986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase"
                     /protein_id="HET2611935.1"
                     /translation="MKIDITNQVKDEFLISLKTLISYPSVLNEGENGTPFGQAIQDVL
                     EKTLEICRDIGFTTYLDPKGYYGYAEIGQGAELLAILCHLDVVPSGDEADWQTPPFEA
                     TIKDGWVFGRGVQDDKGPSLAALYAVKSLLDQGIQFKKRVRFIFGTDEETLWRCMARY
                     NTIEEQASMGFAPDSSFPLTYAEKGLLQVKLHGPGSDQLELEVGGAFNVVPDKANYQG
                     PLYEQVCNGLKEAGYDYQSTEQTVTVLGVPKHAKDASQGINAVIRLATILAPLQEHPA
                     LSFLATQAGQDGTGRQIFGDIADEPSGHLSFNVAGLMINHERSEIRIDIRTPVLADKE
                     ELVELLTRCAQNYQLRYEEFDYLAPLYVAEDSKLVSTLMQIYQEKTGDNSPAISSGGA
                     TFARTMPNCVAFGALFPGAKQTEHQANECAVLEDLYRAMDIYAEAVYRLAT"
     gene            complement(19153..19443)
                     /locus_tag="VQ543_001213"
     CDS             complement(19153..19443)
                     /locus_tag="VQ543_001213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000501069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2611936.1"
                     /translation="MGALGYYEGFVPYVSNQYKNQAEEEGKPLSDKYIFEKILGKTYA
                     AFKKDQINERVEKLGKLKPITINYNGKSEVIDSKEKLQELMNKAVKDEVAQI"
     gene            complement(19431..19682)
                     /locus_tag="VQ543_001214"
     CDS             complement(19431..19682)
                     /locus_tag="VQ543_001214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000657761.1"
                     /note="The YSIRK form of extended signal peptide directs
                     nascent proteins to the cross-wall site, while signal
                     peptides lacking YSIRK direct proteins instead to the cell
                     pole. A large fraction of YSIRK proteins are surface
                     proteins anchored by sortase-mediated processing of a
                     C-terminal LPXTG motif; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-type signal peptide-containing protein"
                     /protein_id="HET2611937.1"
                     /translation="MKEFQFERKQRFSLRKYAIGACSVLLGTSLFFAGMGDQPVQDTE
                     TSSALISSHYLDEQDLSEKLKSELQWFELENKLLNLWEH"
     gene            complement(20081..20965)
                     /locus_tag="VQ543_001215"
     CDS             complement(20081..20965)
                     /locus_tag="VQ543_001215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001838996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HET2611938.1"
                     /translation="MIFLIVCVLLLVIVTLSTVYVVRQQSVAIIERFGKYQKVANSGI
                     HIRLPFGIDSIAARIQLRLLQSDIVVETKTKDNVFVMMNVATQYRVNEQSVTDAYYKL
                     IRPESQIKSYIEDALRSSVPKLTLDELFEKKDEIALEVQHQVAEEMTTYGYIIVKTLI
                     TKVEPDAEVKQSMNEINAAQRKRVAAQELAEADKIKIVTAAEAEAEKDRLHGVGIAQQ
                     RKAIVDGLAESITELKEANVGMTEEQIMSILLTNQYLDTLNTFASKGNQTIFLPNTPN
                     GVDDIRTQILSALRAEKK"
     gene            complement(21110..22261)
                     /locus_tag="VQ543_001216"
     CDS             complement(21110..22261)
                     /locus_tag="VQ543_001216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase"
                     /protein_id="HET2611939.1"
                     /translation="MAIFYVPAVNLIGKGVVNEVGPYIKELGYKKALLVTDKYIEGSD
                     ILPKTLKPLDTEGIEYVIFSDVEPNPTCKNVTDGVAALQEHRCDFIISLGGGSPQDAA
                     SCISIMATNGGKPQDYEGLHKSAKKGLPVVAINTTAGTSAEITINYVITDEERKVKMV
                     MVDKNSLALISVNDPELMLSKPQALTAATGMDALTHAVEALVTPGAYDVTKKLSIGAI
                     ELIKEYLPRAVENGHDIEAREGMVNAIFLGGMSFNNAGLGYVHSMAHQLGAVYNLPHG
                     VCCAMLLPVIEHENAKRVPEAFRNVAKALGLHVEGKSDQECADYAIVEIEKLSETVGI
                     PKKLTELGIEEKDFDFEYLSKNALIDACAPGNPFMPTLEETIAFYKELF"
     gene            complement(22407..24173)
                     /locus_tag="VQ543_001217"
     CDS             complement(22407..24173)
                     /locus_tag="VQ543_001217"
                     /EC_number="5.3.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-fucose isomerase"
                     /protein_id="HET2611940.1"
                     /translation="MIQHPRIGIRPTIDGRRQGVRESLEVQTMNMAKSVADLISSTLK
                     YPDGEPVECVISPSTIGRVPEAAASHELFKKSNVCATITVTPCWCYGSETMDMSPDIP
                     HAIWGFNGTERPGAVYLAAVLASHAQKGIPAFGIYGRDVQEANDTDIPEDVKEKLLRY
                     ARAALATGLMRDTAYLSMGSVSMGIGGSIVNPDFFQEYLGMRNESVDMTEFTRRMDRG
                     IYDPEEFERAMVWVKEHIKEGVDRNREDLILSKEEKEKQWEFVIKMFMIGRDLMVGNP
                     RLAELGFEEEAVGHHALVAGFQGQRQWTDHFPNGDFMETFLNTQFDWNGIRKPFVFAT
                     ENDSLNGVSMLFNYLLTNTPQIFADVRTYWSPEAVKRVTGHTLEGCAAAGFLHLINSG
                     SCTLDGTGQATRDGKPVMKPFWELEESEVQAMLENTDFPPANREYFRGGGFSTRFLTK
                     GDMPVTMVRLNLLKGVGPVLQIAEGYTLELPEDVHHTLDNRTDSGWPTTWFAPRLTGK
                     GAFKSVYDVMNNWGANHGAITYGHIGADLITLASMLRIPVNMHNVPEEDIFRPKNWSL
                     FGTEDLESADYRACQLLGPLHK"
     gene            complement(24230..>25876)
                     /locus_tag="VQ543_001218"
     CDS             complement(24230..>25876)
                     /locus_tag="VQ543_001218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001031112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="discoidin domain-containing protein"
                     /protein_id="HET2611941.1"
                     /translation="NYRTDKTAMWALSGNFDASKSWKKEELELANWISKNYSINPVDN
                     DFRTTTLTLKGHTGHKPQINISGDKNHYTYTENWDENTHVYTITVNHNGMVEMSINTE
                     GTGPVPFPTPDKFNDGNLNIAYAKPTTQSSVDYNGDPNRAVDGNRNGNFNSGSVTHTR
                     ADNPSWWEVDLKKMDKVGLVKIYNRTDAETQRLSNFDVILYDNNRNEVAKKHVNNLSG
                     ESVSLDFKEKGARYIKVKLLTSGVPLSLAEVEVFRESDGKQSEEDIDKITEDKVVSTN
                     KVATQSSTNYEGVAALAVDGNKDGDYGHHSVTHTKADSNAWWQVDLGEEFTVSKVDIY
                     NRTDAEPQRLSNFDVIFLSSSGEEVFRRHFDKVVDGLLSLKVPSVGAKLVKIELKSAA
                     IPLSLAEVEAYGSKRTPKKLSNIALTKETRQSSTDYNGFSRLAVDGNKNGDYGHHSVT
                     HTKGDSPSWWEIDLAQTEELEKLIIYNRTDAEIQRLSNFDIIIYDSNNHEVFKQHIDS
                     LESNNLSIDLKGLKGKKVRISLRNAGIPLSLAEVEVYTYK"
BASE COUNT         7331 a         5790 c         5047 g         7708 t
ORIGIN      
        1 tgaaatacta agcctacaca gactgatttc aattttacca ttcttcatag tcaaaaccat
       61 cataatctgg atattgttct ggcaacgttc caaccgaacg tacgagataa gcttcttcgt
      121 cctctgtctc gatttctctc agcacttagc attcaaaacg ccattcatca ccgaagtcga
      181 aaataaactt aaatttttgt ttgacactta ggctatccag atagacattt tctatgtaac
      241 gttcttcaac atcgtcacta acaaagctaa gaaagtaaga atctgcatga ctccactcaa
      301 cattatccat gaaaaatgca tgagcatgat catttgcaaa atcgaaactc cataaaatca
      361 catctgctag ttccgctaac gtttttgttt ttggaatcta tatatgtcgg tagcaacctt
      421 ttttaatttg acggaaatga tccaagcttc tacagatgct ggcttttcag cttctatttc
      481 ttgttttact aattttaact gtagcatttg aaaccagata attcttctgt ttcacgcgaa
      541 acaccctgcg ccaagcaagg tgttcttgtt tttatactca atgaaaatca aagagcaaac
      601 taggaagcta gctgcaggct gctcaaaaca ctgttttgag gttgtagatg gaagctgacg
      661 tggtttgaag agattttcga agagtattaa gtcgtataaa tcgtcgaagc tgtcgcaatg
      721 gtatgccact ggttagctgt agttgctgcg aaatccttgt ctgcgtagaa gtcagtaaat
      781 ggtaggattt caacttccag ctcgtcgatg cggtcaagct ggccagccag ataaacctcg
      841 atacggcttt ctgctcgttt gatgcgttgc aagagtccgc ccatacggat gtcaactgta
      901 tccaaaccaa agaccttgtt ttctttcagc cattggtgac taaagagggc atggaagtct
      961 tcaatttggc ttctaagttc tggtaattct tgtctggcga tttgttgtaa actttcttta
     1021 tcatccgctt ggtaggcctg acgaatgcgt cgtcccacat ctactttgct acttaaaata
     1081 gcattcaact gggcctgagt ttcaaagaga taagcatagt ttccagcttt ttctttaatg
     1141 ttagcaagcg tctcagcagc ctgagcgaag tgcggtttgt cctgttcagg tgtcatgtgt
     1201 tgatcaagaa tcggacaaag aatatcctga taaaaaacat agcggttggg attgataccg
     1261 ctgagattgc ctggtaggtc tggtaagagg ttggcaaggt caatctgcat aaaatcctca
     1321 accgttagac cagtattggt cttgaagtgc gcagacaaac catctaggtc attgcgatag
     1381 ctgagttctg cccagatttg caagcttggt aggatagaga actgggcagt ttcaccacca
     1441 ttgtctcccc aacccgttac gatgacttct ttaatctgat tggcacggca ggctttatta
     1501 gcctcgatag ccactagacg gctaaaatgg ttgtgaggtg taaagccaat ccacttccaa
     1561 gctccccctg caaatgcaag gtcatggcta atcttgtgat gattgcggaa attacggttg
     1621 tatttttcct cgctatcctg ataataatcc cagtaaacca gagtcacacg gtctttgaga
     1681 cggtctaggt agacacgagt ttcctctgga atttccacat cacggtcgta ctggccatcc
     1741 gctgacatga gtttgaagaa catatcactc cacatctggc agtggaaacc atatttgtca
     1801 gcaatatcca gcacgcgctc caagtgttgg cacatgagga gactacgatc cacaacaccg
     1861 ttcaaaatca ggtagcgtcc caaaccaacc aagtgggctt cgtccatccc gatattgacc
     1921 ttgcgagtct tcagtttaga caacgtggca aacatgccat caatcaggtc ataaaccttt
     1981 tcttcgccaa tgagaagaat gtcctctaca tcacggagct cctgcacttc cttgacaccc
     2041 catttgacaa aggccgacaa gtgggccaag gtctggatgc atggtacaaa ggtcatgtca
     2101 aactgttgag cataggcttc gatttcctgc aactcctctg ctgaataagc tccacggaaa
     2161 tagccaaagt aaggctgccc ttcaatctgg taagtgtctt ccatgtaaag ttcaaaggtt
     2221 gagtagccca tgagagccaa gacctcaatc atctgcttgg cagaagccac attcagcacc
     2281 gcatttcgag aacagtcaac catgtaagcc aaatcttcgt aagctgcttg ttcctcaatc
     2341 tctactttat cagcttctgc tagaactgtt accaacaagg ataaggcacg ataaagttgg
     2401 tgaggtttgc ggtaggtcaa ttgatagtga ccttcctcac cctggataga gatagaggct
     2461 tggtcagact gagtgacagc cacttccaca tctggtagag aaatatgacc ttttaaaacc
     2521 tcaatagctt gcgtttgttt gggactaagt cctgtaaatc ttaccattgc ttttcctcct
     2581 gtagccagtt gacaagagca ccgtagagat tggcatctgc gtgataggtg caggcctgga
     2641 taactggtgc gaccgtgtat tcttcgtagg tatcgacaaa gttatcaaca gccttcttga
     2701 catcttggat aaaatctgga ttttgactga tagagccacc cagactgatg acatctggat
     2761 cgatcagata ctggatattg agcaagcctt gcgccagatt gcggttcatg cgctcaatgg
     2821 cttcttgaca aaggatatta ccagctgcgg cctcttggta aatcttgcga ccgtcccaat
     2881 cagtatgacc agatttttca atcacgtatc gtaccatatt cccagttgat gctagttgcg
     2941 accagttatt aagtttttca gcaggggcaa gggttgtcat gtagccaaat tctccaccca
     3001 agccgtggcg acctcgatga agtctaccat tgataatcat ggctccgcca atccctgtcc
     3061 caatcacgac acaggctgca ttttcaagat ctggatgagc tagtagttca ctgagtccaa
     3121 cgcagttggc atcattttct aaatggacag gtagctgata agagctaagc gcctcatacc
     3181 aagaaaagcc atggatgtag ggcaccgcac tgaagccatc aatcacacct gtctcttgat
     3241 tgactgcacc tggaacgctc atagcaatcc cactgtaatc ctgttctgac aagcgttgat
     3301 ctagccacgc tagtaaatcc tccaagtttt caggcgttga aatacttgtc ttatccagta
     3361 ttttcccatc aggagtcaga ctggcaaact taatcccagt ccctccgata tcaatcgttg
     3421 caatggtcat tgtttttacc ataaaaaggg gcgaatcagc agttagttct tactttttcg
     3481 cccctccttt cttttgatgt ttactttttg aaattaaatt tcttcttttt tgatgaattc
     3541 tgtacgaatc tcttgtggat ccaatggtcc tgaatgaact ggatatggtc gctcaagtaa
     3601 gtcaagaatg gtttgttgat gttctgatat gtgcacattt tcttgactca tattatagta
     3661 acggaagaca tagccttctt cattttccgc cactttaaag gctgttggac aaacttgcgg
     3721 tatgctgaga acagaatggc tcaagaggct accagtcgca accacgcttc cttcctgtct
     3781 agcaagctga aggctggtaa acggtgtctg caaggctttg gcacgacgga aagctgaaaa
     3841 gcgttcttgg gcttggtggc attcaagtgc aaactcgact tcaaactcac gcaagcattg
     3901 tgcttctggc gttgggaagt agccccagtc acctagctca cctgatgcac gcaaaatggt
     3961 cacggcaatg gtgttatccc caaggatttc gtattcattc aatcccttat tggatacagt
     4021 cacccctttt tcatcgtcat acagactgac aaaagcttgt tggtgttgag gattttcagg
     4081 attttcccat gaagcagctg gtttgtttgg tcgtgtcacc acctcataga tactttcaga
     4141 atcattgctt ggacgcgtgt tatgagtctt gaccaagaga cggatacggt gatccttggc
     4201 agtgttagta aagcgagtct tgaagcggat ttgtggattg tcaacaaaga caatcaactc
     4261 agtttccaga ggaatgtttg tcaattcttc tgaccgtcca gcctcacgct tcataaactc
     4321 gatgatacct tgttgctctt cttctagctt ttcatccgca ctgacaggca cggtcaattc
     4381 atgtttgagc aagattttag catagcgatc tgtgttttcc aagacctcgt ggcccttaag
     4441 ctctgcaaag attggctctg ttccttttgg ttggaaatag atatactcgt ttccgatgtc
     4501 cccacggtct tcgaagcgga taaagtcttc ataggcttcg tgagttgtct tgtcatatac
     4561 tgtgatattg tcatccacac tcaccgttac gaatggtgta tcaatcactc cgttttggta
     4621 aataccctca cggtgttctt gttttccttc cagcaattgg aaggttgtcc aagaaagcgg
     4681 cgctaggtga actggaatgg tcacgcgcac ttgtcgagca atacgagctt ggcggaactt
     4741 gtcttttggt aaatcgtact caaaattagc tccgaggtct tcgattgtag cctctacagg
     4801 acgaccatcc aagtcctcca cacggtaact tggtaagata agagcagcca tctttttgta
     4861 gccttctgtt gggtgcaatt ccttgaaatc acaagtcgcc acatcaatca ctgtgctgac
     4921 agtatcgacc ttatcatgca agcctgtgtt aatgacagta aagagatagt cactttgagc
     4981 cttatccgta gcaattttac ccttccactc gttgagcaag ttacttttaa caaagtttcc
     5041 tacttggttg accttggcaa aacgcgtttc catctcgcgg tgaacttcgt ccacgctaca
     5101 gccacagata ctatcatgtg gcgcattctg caaaagtgtt ttccaagcat aggtcaactg
     5161 gtccttgtgg ttgtgtccac cagtgataat agtcaagggt tctaccactt gctctaggag
     5221 gttgctattt tcttggaagg cttgttttag gtaaatgcgg gatgaagaag tgttggcaag
     5281 tgtgtaccag ccatctgttt cctgactggt caactcgcct gtaacagttg ataagtgttc
     5341 aggaagcgca ccttctacag cttgaacata ttcatcaaaa gaactatgaa caaagattac
     5401 atccgggaag agttcatttg ccacacgaat ggcttcgctc agatttttct gtacaggctg
     5461 gtggtcacag ccgttcatca tcaaccattg gttggtcgaa gcgtaggcac gcacatctga
     5521 caatttttgt ttccagaagg tcaaggcctc atctttgtca actgggattt cattcccatt
     5581 actgtaccag ttggcaaaga gaatacctaa aacacgacta ccatccacac cctgccagta
     5641 catttctgaa aactgggatg taaaccgctc atcttcaagg acttggttgt caaatccaat
     5701 cggcttcaca ccacgaccaa aggctgccac gtgaatacct gatttttgaa ggatttgagg
     5761 agcttgtccc atatttccaa aggtatctgg aaagtagcca atctgggttg atttacccca
     5821 tttggcagct tcttgttgac caatcaaggt attgcggaca ttggcttcac tggagatcaa
     5881 gtagtcatcc tgcaagatgt aaaagggacc aattttaagt ttgccctcgt caatgtagcg
     5941 ttggaccttg tcgcgatttt cagggcgaat ttgtaagtag tcatcaagga caatagtttg
     6001 tccatccaag tggaaactct tgaactcagg gtcattttca aagagatcaa agagattgtc
     6061 aaacaattcc accaactgca tacgatggct ttcaaaaggc aagtaccact cacgatccca
     6121 gtgactatgt gagataatat gtacaacaac attttccatg aagtaaaacc tcattctaaa
     6181 tttaaatttt aacgttttaa atgtaaactt gtgattctga taagaatcgg ttgagctaaa
     6241 gcgagcccct tagcggatat ccaagtaatc caagaccaac tcacagaaca tcatgttagc
     6301 ccaggagaac cattcacgag agtagagggt cggatcatct acgtggaagc tttcgtgcat
     6361 gacacctgta ccaccatcgc aggcaaccag ctgatccagc aagaattttt tctctgcctt
     6421 atctcttgtt gtcaatcctt ggatagaaag ggcgattggc cagatatagc gatagaaggt
     6481 atgagaactt ccgagaccgc tagcgtattc tccttggtag aagtatggat tttcagagct
     6541 cagaatggta cggcgagtgg cttgatacac ttcatcatcg atcgaacagt agcccagata
     6601 gggcgcagct agtagacttg gtacatttgg atcatccatg atgctggcat ttcctaggcc
     6661 atctacttca aaagcgtaaa tcttttcgcc cttgctgttg gtggtgtaag cgtagttttc
     6721 gattccttct tggatttcat cctgaagacg cttggcatca gcaataacac tctggctatc
     6781 agctaggttt aatgctgcga agatttcttg cacataaccc aagactacta cagcaaacat
     6841 atttgacgga atcaagtaac tatactggca acagtcatca ctcggacgaa aagctgacca
     6901 agtcatacct gtcactgcaa agtcaggtcc aaagccatca tttaccaagg tgtcttcctt
     6961 acggtccgta tctcggacaa aacgataagg agagttcttg tggtcttgtt caactgtcca
     7021 tagatggaga atttccttag tcgctgcgac aaaagtttca tcaaactgac tagtctcgcc
     7081 agtctctttc cagaggagat aagccaactg caaaggatag caaagcgaat ccacctcata
     7141 cttgcgctcc cagatccagc cgttaaggtc tgtgtggtca gtctcgtggt gccctttcca
     7201 gttctcctca atgttgaagg agttagcata gggatccttg agtaccaagg tcatctgacg
     7261 tttgaccaaa cctgcaatgg tctgacgcag gagggcatct cttttagcta catgaaggta
     7321 gggtctgagt tgggctgtcg aatctcgaag ccacatggca ggaatatccc cagtcaagac
     7381 aaaagttgaa ccatcttcta agatttcaac cgtattgtcc aaggtatcgg tgtagcaacg
     7441 ctcaaagaca tcaacccact ctggatggtc cttggcccgc tctgctactt catctagcca
     7501 ttctctaaca atttctttcg aataaatcat cgtgcaattc cctctttcaa acaagtttca
     7561 tgttcagtat atagcttttg agacagaaaa tacatacaca aatgatagtc atttttctac
     7621 aaaatagtta tctttaaaac tccttttcta aaggccctct ttttctgata taatgtagaa
     7681 aaacagctaa aggaaagact atgaaaccac tacttgaaac catcgatacc cgctttggta
     7741 ctgctagcaa gcatgccttc tctcggggaa ataccctgcc atacacaggc gtgccttttg
     7801 ggatgaatta ctttgtgccc cagaccagtg accaggatgg atcttggttt tttgatccgc
     7861 atctgcctat ctttcagggg attcgattaa ctcaccagcc cagtccttgg attggggact
     7921 actcttggct ccttctgaca cctgtcacca gtcaactggg gggagacagc ctctttcacc
     7981 gccagtcttc ttatgatata gataaagctt gcttccagcc tcactatttg aagctctttt
     8041 ctctgcgtta tcagattgaa acccagctca caccgacttg ctatggtgct tctattcgtt
     8101 tgaatcaaaa gcaaggcaaa gccctctccc tctatcttca cgcagcagat gaactgacag
     8161 tagagcaagt agataagcgg actcttgccc tgcgacaaga aggtaaaact gaaactaaca
     8221 aaaattcgct aacgatgttc actgccctgc aaatgaacac ggatattctt gctatcagcc
     8281 aagaagctgg ggactggcga attgacttag caagtagtca aaccgagatg caactagcca
     8341 cttctttcat ctctccttct caagctctaa tcaatctacc tcaagaagat tttgatagct
     8401 gtaaaacaag tgcccaagcg gattgggaaa atctcctcca tcgttttgac attatagaga
     8461 caggagaggc tgaccgaacc ttctttgacc actgcctcta cagactcttc ctcttcccac
     8521 agacttttta tgaggttgat gagtcaggga aagccatcca catggatctg gctactggta
     8581 ctgtcaagcc tggtgtcctc tttagcaaca atggtttctg ggataccttc cgcaccacct
     8641 tccccctctt tgcccttatc ataccggagc actatcaacg ctttttagaa ggtttcctca
     8701 atagctaccg cgatactggt ttccttccaa aatggctggc tccagatgaa cggggtatga
     8761 tgccaggtac actgctagat ggcattatcg cagatagcgc ctgtaaggac atggcccccg
     8821 acctagaagg agaactcttc caagccatgc tcgaaacagc cagcaaagcc gaccctctcg
     8881 gcatcaatgg ccgccacgga ctagcccaat accaagaact aggttacctc tctaccgacc
     8941 accacgaaag tgttagccat actctagact atgcctatag tgacttttgt atcgccagct
     9001 gtgccaaaaa actagagaac atagaaatcg ctgaaaccta caaggctgct tcacaaaatt
     9061 accgccagct atttgacgct gagacaggtt acatgcgagc acgagacaat caaggaaact
     9121 ttcaccctga cttctctcct tatagttggg ggcgagacta cgctgaatgc tctgccattc
     9181 aagctacttt aggcgttctc cacgacatcc ctggcttaat ccaactgatg ggtggaaaag
     9241 aaacctttag caactatctt ttgaaagcct gtcaagatgc tcccctcttt gaaacaacag
     9301 gctatggtta cgaaattcac gaaatgagcg agatggctac tgctcctttt ggacaaatag
     9361 ccatttccaa ccagcctagt ttccacattc cttatctctt ccgctacagc gattaccctg
     9421 actacactgc ccttcttatc aagacgctcc gtcagaaagc ttttcaccca agttgggaag
     9481 cctatcctgg agatgaagac aatggtagtc tctctgcttg gtacatctgg tcagctctcg
     9541 gattttatcc aacctgtcca ggaaaaccaa gctatgatct cggaatccct ctctttgacc
     9601 atctacgagt ctacctagct aaagaaaata aatggctaga tattcatact gagcaaaacc
     9661 acagccattt taactttgtc aaagaatgcc gactggacaa aacactcgta tcaactattc
     9721 aacaccaaga cctcctaaaa gctgaacaac taactttcac cctcagctgg ctaccaaatc
     9781 actaataacc aaaagaacct ttgcatcgcg caaaggttct tcttttatga aacttggact
     9841 tgaagttgat ccacaagctg accatccacc gttaggttca gatagaaatc caaggtttta
     9901 tctcctgcga aatacaaggt tggtagcgtc agcctttttt cagtctcacc agcttgaaac
     9961 gcaaggacat aaatctcgtc ctgataggcg acaccatgga cacctgtccc cggttgaatc
    10021 gaaatcttag cctctaaaga ggagctactt tcactacgtt caatcctaaa atgaagagtc
    10081 tctccctttg ccacagctag gcttttttct gcaaatgcta gttcctgaac aacttctttt
    10141 tttgataacc caggagtttt ataaagggaa atcttggtca atacagggat agattgtgcc
    10201 tcggtaatca tcacgcgcac cttttgtgcc tctactagcg gacctcgcaa gaggcgctta
    10261 tgaccaactg tgaagcccct gccaaactcc tgccagacac catccacctc tacttgcaca
    10321 tgaaaagcag cgattcgttg ccctagcttc aaatcttctc ttaactcaat tacatcaaaa
    10381 gttttaggag aacctaaatc gagttctaac tggatgggca agtctgcatc gcttgcccaa
    10441 gagctggtct caaggccgtc tgtcaaatgg cgacaatcaa agtctgcgga aagagctgga
    10501 ccagatacct cagctcccag agccaaatct tctttataga gctcattgcg ataggtcgca
    10561 aattcataaa gtcgttcaat atcctttgca tcaaagagcc cagcttgatt cggcggaata
    10621 ttaagcaaga gtggagttcc tcgccctact gagtgaaagt agatttcgac caactcctcg
    10681 agagacttag gatcctgatc ctcatggtag aaccagcctg gacggatgga aacatctgcc
    10741 tctccgattg aaaaaatcgt gcccgaggga tccccgtgct gaagatagtt cagctctgct
    10801 tctgttccta gtttatcaag attcaccttt tgccacagtg gatcacctgc ataccctcgt
    10861 tcattgccaa tccagcggat actggtgcct tctgttgaaa aaatcaagca atcgccctgc
    10921 aggtcacgaa tggtttcaaa ccatttttca aattcataat taaccttttg cgcgccctct
    10981 cctctggcac catccatcca aacctcagcg aacttaccag cattcccata gttaggattt
    11041 gataagattt ccttcaactg agccagataa taggcattgt agtccgcttc tcggtccaca
    11101 tgatagaggg gactatgggc atcccacggt gacaggtaga cccccatatc catatcaaac
    11161 tctgtggcag cttgggatac ttcaaggagc aagtcgccct ttcctctcct ccaaggactg
    11221 accttaaccg aataatctgt gtgagctgtc ggataaagga caaagccatc gtggtgcttg
    11281 accaccaaaa tcaacttttt gaagcccgtt tccttgagca cacgaaccca ctcacgcgca
    11341 tccaactgac tcgggttaaa gcgctcagga tcctcctgtc cagtccccca ttcttggtca
    11401 taaaaggtat taggaccgaa gtggataaaa gctgctagtt catctcccag ataagctagc
    11461 tgagtctgac ttggtaacgg tccatgcggt ttgattttct tcatcgttat atatctcctt
    11521 cttttgcaac ttctcttgtt cacaaggtta tccacaggtt gtggataata aaccatgatc
    11581 taacagccag ctctttccaa ctccaactgg taggctcagg atttttctcc tcaatgttcc
    11641 ctcttcaaac agctctgtca tatggttctg ctaacacctc tcagaatgct actctccata
    11701 attattctca ggcttctttc aggtcattgt gtgaagacca ttcactctcc agacttttcc
    11761 acagattgtg aataagtgat tattctaagc tatcacctcg tcgactataa caaaaaataa
    11821 aaagagggtc aataagataa ttatctcttc ctaaatactc agaaaagatt ctataatttg
    11881 tacaattgaa caagaaatgc ttctccaaaa tctatcttca aaagaatgtt gcatcttttt
    11941 atcctttcac acaaacattt ctctttatac agatccaagt gataaccaga tgataattgg
    12001 acactttttg gtcatttgta tattttttga aaaatttttt aaaaaaattt tatatccttt
    12061 ttatagaagt ttatgcattt gtatctatgt attctatcct atgttatgta taataacata
    12121 aaattgtgct aaacatcata atttatatta ttttccgaga aattatagcc attgacatta
    12181 cctaggaatt gcgttataac atacatgtaa gcggtaccca aaatggtgcc aagtcaaaat
    12241 ttttaaggag gaaaatacat gtcttctcat ccaattcagg tcttctcaga aattgggaaa
    12301 ctgaaaaaag ttatgttgca ccgtccaggc aaggagttag aaaacttgtt gccggactat
    12361 cttgaaaggc ttctttttga tgatattcct ttcttggaag atgctcaaaa agaacatgat
    12421 gcatttgccc aagctcttcg cgatgaagga attgaggttc tctacctaga acaactcgct
    12481 gctgaatcat tgacctctcc agaaatccgc gatcaattta tcgaggaata cttagacgaa
    12541 gccaacatcc gtgatcgtca aaccaaggtt gctattcgtg aattacttca cggcatcaag
    12601 gacaaccaag aattggttga aaaaacaatg gctgggattc aaaaagttga attgccagaa
    12661 attcctgacg aagctaaaga tctaactgac ttagttgaat cagattatcc atttgcaatt
    12721 gacccgatgc caaacctcta tttcactcgc gacccatttg caacaattgg aaacgccgta
    12781 tcgcttaacc acatgtttgc agatactcgt aaccgtgaaa cactctacgg taagtatatc
    12841 ttcaaatacc acccaatcta tggcggaaaa gtggatttgg tctacaaccg tgaagaagat
    12901 acgcgtatcg aaggtggaga cgagctaatt ctttctaaag acgtccttgc agtaggtatc
    12961 tctcaacgta cagacgcagc ttctatcgaa aaacttttgg tcaacatctt caagaaaaat
    13021 gttggcttca agaaagtttt ggcctttgaa tttgctaaca accgtaaatt catgcacttg
    13081 gatactgtct tcactatggt agactatgac aagttcacta ttcacccaga aatcgaaggc
    13141 aaccttcacg tttactcagt tacttacgaa aacgaaaaac ttaaaattgt tgaagagaaa
    13201 ggtgacttag ctgaacttct tgctcaaaac cttggtgtag aaaaagttca tttgattcgt
    13261 tgcggtggtg gcaatatcgt agcagctgcg cgtgaacaat ggaacgacgg ttctaacact
    13321 ttgaccatcg cacctggtgt ggtagttgtt tatgaccgca ataccgtgac caataagatt
    13381 ttggaagaat acgggcttcg cttgattaag attcgcggaa gtgaattggt tcggggccgt
    13441 ggtggacctc gttgtatgtc tatgccattt gaacgtgaag aagtgtaatc gctgttcggt
    13501 attcgtcaat agaaaatgta aaaaatagaa agaggaaata ataaaatgac aaattcagta
    13561 ttccaaggac gcagcttctt agcagaaaaa gactttaccc gtgcagagtt agaatacctt
    13621 attggtcttt cagctcactt gaaagatttg aaaaaacgca atattcaaca ccactacctt
    13681 gctggcaaga atatcgctct cctatttgaa aaaacatcta ctcgtactcg tgcagccttt
    13741 acaactgcgg ctatcgacct tggtgctcac ccagaatacc tcggagcaaa tgatattcag
    13801 ttgggtaaaa aagaatctac tgaagatact gctaaagtat tgggacgtat gtttgacggg
    13861 attgaattcc gcggattcag ccaacgtatg gttgaagaat tggcagaatt ctcaggcgtt
    13921 ccagtatgga acggtctaac tgacgaatgg cacccaactc aaatgctcgc tgactacttg
    13981 actgttcaag aaaacttcgg tcgcttggaa ggcttgacat tggtatactg tggtgatgga
    14041 cgtaacaacg ttgccaacag cttgctcgta acaggtgcta tccttggtgt caatgttcac
    14101 atcttctcac caaaagaact cttcccagaa aaagaaatcg ttgaattggc agaaggattt
    14161 gctaaagaaa gtggcgcaca tgttctcatc actgaagatg ctgatgaagc agttaaagat
    14221 gcagacgttc tttacacaga cgtttgggta tcaatgggtg aagaagacaa attcgcagaa
    14281 cgtgtagctc ttcttaaacc ttaccaagtc aatatggact tagttaaaaa agcaggcaat
    14341 gaaaacttga tcttcctaca ctgcttgcca gcattccacg atactcacac tgtttatggt
    14401 aaagacgttg ctgaaaaatt tggtgtagaa gaaatggaag taacagacga agtcttccgc
    14461 agcaagtacg ctcgccactt cgatcaagca gaaaaccgta tgcacactat caaagctgtt
    14521 atggctgcta cacttggtaa cctttatatt cctaaagtat aattttagat aataaaccgt
    14581 ctaccaacag ctatgagggc tgcgactaat agctttagtc cggtcctctt ttatgtaatg
    14641 gtaatctatt atttcttata aaatatgtga aaaatcatta aattgaaatc taaacgcatt
    14701 ctattgagtg tgataaagga gaatttatgg caaatcgtaa aattgtagta gctttgggag
    14761 gaaatgcgat tctttcttct gacccatcag caaaggctca acaagaagct ttagttgaaa
    14821 cagctaagca tcttgtaaaa ttgattaaaa atggagatga tttgattatc actcacggta
    14881 atggacctca agttgggaat ctcttgctcc aacatttggc atcagactct gaaaagaacc
    14941 ctgccttccc actcgactca cttgtcgcta tgacagaagg tagcatcggt ttctggttga
    15001 aaaatgcttt gcaaaatgct ctcttggatg aaggcatcga aaaaaatgtt gcctctgttg
    15061 taacgcaagt tatcgtagat aaaaatgatc cagcttttgt taacttgagt aaaccaatcg
    15121 gtcctttcta ttcagaagaa gaagcaaaag cagaagccga aaagagcgga gcgactttca
    15181 aggaagatgc tggccgtggc tggcgtaagg tcgttgcctc accaaaacct gttgacatca
    15241 aagaaattga aaccatccgt actcttttaa ataatggtca agtcgtcgta gctgcaggtg
    15301 gtggcggtat tcccgtcgtc aaagaaaaca atggacattt gactggtgtc gaagcggtta
    15361 ttgataaaga cttcgcttcc caacgtttgg cagaattggt tgatgcagac ctcttcatcg
    15421 ttttgacagg tgtagattat gtatttgtta actacaacaa gccaaaccag gaaaaattgg
    15481 aacatgtgaa tgttgcccag ctggaagaat atatcaaaca agatcagttt gcaccaggta
    15541 gcatgcttcc aaaagtagaa gcagctatcg cttttgtcaa tggtcgtcca gaaggaaaag
    15601 cagttattac ttcccttgaa aatctaggcg ccttgattga atctgaaagc ggaacaatta
    15661 ttgaaaaagg ataagttgtt ttactaataa gatgtattct atttctagta tctttatatc
    15721 aaattagaaa ttattcttga aaacatgtac aatatttcaa aagatactag ttttagactt
    15781 taatatggta aaacaaatat aaatagaaag cgttttcttg aatgtttatt taagaaagta
    15841 gttggttttt tacactttgt tagacatcag gaggaaaaac aaatgagtga aaaagctaaa
    15901 aaagggttta agatgccttc atcttacacc gtattattga taatcattgc tattatggcc
    15961 gtgctaactt ggtttatccc tgcgggggcc tttatagaag gtatttacga ggctcagcct
    16021 caaaatccac aagggatttg ggatgtcctc atggcaccga ttcgggctat gctaggtact
    16081 catccagagg aaggttcgct cattaaagaa acgagcgcag cgattgatgt agccttcttc
    16141 atccttatgg ttggtggttt ccttggcatt gtcaacaaaa ctggtgctct tgacgtaggg
    16201 attgcctcta tcgtgaagaa gtataagggc cgcgaaaaaa tgttaatttt ggtattgatg
    16261 cctttgtttg ccctcggtgg tacaacttat ggtatgggtg aagaaacaat ggccttctat
    16321 ccactccttg tgccagttat gatggccgtt ggttttgata gcctgactgg tgttgcaatt
    16381 attttgctcg gttctcaaat cggctgtttg gcatctactc tgaatccatt tgcgacaggt
    16441 attgcttcag cgactgcggg agttggtaca ggggacggta tcgtacttcg tctgatcttc
    16501 tgggttacct tgactgctct tagtacttgg tttgtttacc gttatgcgga taagattcaa
    16561 aaagatccga ctaagtcact ggtttatagt actcgcaaag aagatttgaa acactttaac
    16621 gtagaagaat cttcatctgt agaatctaca cttagcagca aacaaaaatc agttctcttc
    16681 ttatttgtgt tgacattcat cttgatggta ttgagcttca ttccatggac agaccttggc
    16741 gttaccattt ttgatgactt taatacttgg ttgactggtc ttccagttat tggtaatatt
    16801 gtcggttcat ctacttctgc actaggtact tggtacttcc cagaaggcgc aatgctcttt
    16861 gcctttatgg gtatcctgat tggtgttatt tatggtctta aagaagataa gattatctct
    16921 tccttcatga atggtgctgc tgacttgctc agtgttgcct tgatcgtagc gattgctcgt
    16981 ggtattcaag ttatcatgaa cgacggtatg attaccgata caatcctcaa ctggggtaaa
    17041 gaaggcttga gcggtctatc ttcacaagtc tttatcgttg taacttatat cttctatcta
    17101 cctatgtcat tcttgatccc atcttcatct ggtcttgcca gcgcaactat gggtatcatg
    17161 gctccacttg gagaatttgt aaatgtccgt cctagcttga ttatcactgc ttaccaatct
    17221 gcttcaggtg tcttgaactt gattgcacca acatctggta ttgtgatggg agctcttgca
    17281 cttggacgta tcaacattgg tacttggtgg aaattcatgg gcaaactcgt agtcgctatt
    17341 attgtagtga ccatcgccct tcttctcctt ggaaccttcc ttccattcct ataaaatagt
    17401 gagtgaggtg attccatgaa aatagatata acaaatcaag ttaaagatga atttcttata
    17461 tcattaaaaa ccttgatttc ctatccttca gtactcaatg aaggagaaaa tggaacacct
    17521 tttggacaag caatccaaga tgtcctagaa aaaactttag agatttgtcg agacataggt
    17581 ttcactacct atcttgaccc taaaggttat tacggatatg cagaaatcgg tcagggagca
    17641 gagcttctgg ccattctctg tcatttggat gttgttccat caggtgatga agcagattgg
    17701 cagacaccgc catttgaagc aactatcaaa gacggctggg tattcggacg tggtgtccaa
    17761 gatgataaag gcccttcgct cgcagctctc tatgcagtaa aaagcttgct ggaccaaggt
    17821 attcagttca aaaagcgcgt acgctttatc tttggtaccg atgaggaaac cctctggcgc
    17881 tgcatggcac gctacaatac catcgaagaa caggccagta tgggctttgc acctgactca
    17941 tcttttcctc tgacctatgc tgaaaaaggg cttctacagg tcaaacttca tggccctgga
    18001 tcggatcaac tagagcttga agtaggaggc gcctttaacg ttgtaccaga caaggccaac
    18061 taccaaggtc ccctctatga acaggtttgt aacggtctca aagaagctgg ttatgattac
    18121 caatccactg aacaaaccgt aacggttctc ggagtgccaa agcatgctaa ggatgctagt
    18181 caaggtatca atgctgtcat ccgactagct accattcttg ctcctctcca agaacaccct
    18241 gctctcagtt ttcttgcaac acaagcaggt caagacggca caggaagaca aatctttggt
    18301 gatatagcag atgaaccttc tggtcaccta tcctttaatg tcgcaggtct catgatcaat
    18361 catgaacgtt ctgaaatccg tattgacatt cggactcctg tcttagctga caaggaagaa
    18421 ctagtagagt tgcttacaag atgtgcacaa aactaccaac tccgctacga agagtttgac
    18481 tatctagcgc ctctatacgt cgcagaagac agtaaactcg ttagcacact gatgcaaatc
    18541 taccaagaaa agactggcga taacagtcct gctatttcat ccggtggtgc cacttttgct
    18601 cgcaccatgc caaattgtgt agccttcggc gccttattcc caggagcgaa gcagacagaa
    18661 catcaggcaa atgaatgtgc cgttctagaa gatttgtacc gtgctatgga tatttatgcc
    18721 gaagccgtct atcgacttgc aacttaatca ggcaactgtt tctaccaaaa aaaatcgacc
    18781 gattaatgaa ctgcacccca aaagttagac agaataaatc taacttttgg ggtgttttat
    18841 tatgaaattg agttatgaag ataaagttca gatctatgaa ctaagaaagc aaggacaaag
    18901 cttcaaacag ctttcaaaaa gatttggtgt ggatgtttct ggtctaaagt catctgaatc
    18961 tttgagatga gctttataaa tcgctttttt cagtttttgc actggtgttt cgataaactc
    19021 aaacttttta gccgtggtat tgcctgattt tatagtatat tgaaactaga atagtacacc
    19081 tctacttcta aaacattttt agaaatcgat ttgactgtcc tgaacgattt gtcctgttct
    19141 tatttcattt tactatattt gagccacttc gtctttaacg gctttattca taagctcttg
    19201 taatttttct ttactatcaa ttacttctga ttttccgttg taatttattg taataggttt
    19261 taacttacct aatttctcga cacgctcatt aatttgatct tttttgaagg ctgcatatgt
    19321 ttttcctaag attttttcga aaatatattt atcagatagc ggtttgcctt cttcttcagc
    19381 ttggtttttg tattgatttg aaacataagg aacaaatcct tcatagtaac ctaatgctcc
    19441 cataagttca aaagcttgtt ttctaattca aaccattgca actcagattt cagcttttca
    19501 gataaatcct gctcatccaa ataatgactt gaaattagtg ctgaactcgt ttctgtatcc
    19561 tgtacaggct gatcacccat accagcaaaa aataaactcg ttcctagcaa gaccgaacaa
    19621 gctcctattg catatttcct caaagaaaaa cgctgctttc tctcaaattg aaattctttc
    19681 atcccatctc ccatcattca ttattactgt atattttgta tatcagaaat agtttgtatt
    19741 cacaaatctt tctagttatt cccttatcat tcctaattaa gggaggtaac atacaataat
    19801 ttttagttaa atgtatatct atgttttttg tttttcttaa taaacgcaat acaaaaagag
    19861 cctgttgcca agctctttgt actcaatgaa aatcaaatag caaactagga aactagccac
    19921 aggttgctca aaacaccgtt ttgaggtagt agataagact gacgaagtca gctcaaaaca
    19981 ctgttttgag gttgcagata gaactgacaa agtcagtaac atctatacgg caaggcgacg
    20041 ctgacgtggt ttgaagagat tttcgaagag tattagtcta ttatttcttc tcagcgcgaa
    20101 gggctgacaa gatttgtgtt cggatatcat ccacaccatt tggcgtattt ggtaaaaaga
    20161 tggtttgatt tcctttagag gcaaaggtat tcaaggtatc caaatactgg ttggtcaaga
    20221 ggatagacat gatttgttct tctgtcatgc caacattggc ttccttgagt tcggtgatag
    20281 actctgccaa tccatccaca atcgccttac gttgttgggc aatccccaca ccatgaaggc
    20341 ggtctttttc tgcttctgct tcagctgcag tgacaatttt aatcttgtca gcttccgcca
    20401 attcttgtgc tgcgacccgc ttacgttgcg ccgcattgat ttcattcatg gattgcttaa
    20461 cttctgcatc cggttcgact ttggtaatca aggttttcac gataatgtag ccgtaagtgg
    20521 tcatttcttc tgctacttgg tgttgaactt caagggcaat ctcatctttt ttctcaaaca
    20581 attcatccaa ggttaatttt ggaacagaag agcgaagagc atcttcgata taagatttaa
    20641 tctgagattc tggacgtatg agtttatagt aagcatctgt cacgctctgc tcgttgacac
    20701 ggtactgagt cgctacattc atcataacga acacattgtc cttggtctta gtctcaacca
    20761 caatatcact ttgcaacaag cgcaactgaa tccgtgctgc aatcgagtca atcccaaaag
    20821 gcaagcgaat atgaataccg ctattagcaa ccttttggta tttcccaaag cgttcaataa
    20881 tcgccaccga ctgctgacga accacataaa ctgtactcag tgtgactatc accaatagga
    20941 gcacacaaac aatcagaaaa atcatgaaaa atattgccat aatggaacct ccacaagtat
    21001 ttttctagta ttatagcaca tttaaagaag gctgtgccgt ttttactgcg atttttcctg
    21061 aaatgtcaat aattagaggt gaattgtcct attgtcgtcc aatctcttgc taaaataact
    21121 ctttataaaa ggcaatcgtt tcttctaagg ttggcataaa tggatttcct ggtgcgcagg
    21181 catcaatcaa ggcattctta gaaaggtatt caaagtcgaa atctttttct tcaataccaa
    21241 gttcagtcag tttcttagga atacctactg tctcagaaag cttctcaatc tcaacaatcg
    21301 cataatcggc acattcttga tctgatttac cttctacatg aagtcccaag gctttggcaa
    21361 cattgcggaa agcttctggt acacgtttag cattttcatg ttctataact ggtagcaaca
    21421 tggcacagca aacaccatgt ggcaaattat atactgcacc gagttggtga gccattgagt
    21481 gaacataacc aagaccagca ttattaaagc tcataccacc aaggaagatg gcattgacca
    21541 taccttcacg cgcttcaata tcatgtccat tttctacagc acgaggaaga tattccttga
    21601 taagctcaat agcaccaata gacagtttct tggttacatc ataagcacca ggtgttacca
    21661 aagcttcaac agcgtgagtc agagcatcca taccagtagc agcagtcaag gcttgaggtt
    21721 tggaaagcat gagttcaggg tcattgacag aaatcaaggc aaggctattc ttgtcaacca
    21781 ttaccatctt aaccttgcgt tcttcatcag taatcacata gttaatagtg atttctgctg
    21841 atgtacctgc cgttgtattg atagccacaa ccggcaagcc ttttttagca gacttatgaa
    21901 gcccttcata atcctgtggt tttccaccat ttgtagccat gatagaaata caactagctg
    21961 catcctgtgg agaacccccg ccaagactga tgataaaatc acatctatgt tcttgcaaag
    22021 cagctacccc atctgtgaca tttttacaag tagggtttgg ctctacatcg ctaaagatga
    22081 catattcgat tccttctgta tccagtggtt ttaaagtctt aggtaaaata tcactgcctt
    22141 cgatgtactt atctgtcacc aaaagtgcct ttttatagcc aagttccttg atataaggac
    22201 ccacttcatt tacaacacct tttccaataa ggttgactgc cggaacataa aatatagcca
    22261 tataattttc ctcctgcgcc tccgcgctat ctatttaaca tcattatatt actttttgta
    22321 ttcgttttca attatttgtg aattgtttaa caaatctttt taaaaggata ggagggacgt
    22381 aagttcacct cctatataaa caagttttat ttatgtagtg gtcccaacaa ctgacatgca
    22441 cgatagtctg ctgattctag atcttctgtt ccaaataagg accaattttt aggtctaaag
    22501 atatcttcct caggtacatt atgcatattg acaggaattc tcaacataga agccaaggta
    22561 atcaagtctg ctccaatgtg tccatatgtt atggctccgt gattagctcc ccaattattc
    22621 atgacgtcat agacagactt gaaagcacct tttcctgtca aacgtggagc aaaccaagta
    22681 gttggccatc ctgaatctgt acgattatct aaagtatggt gaacatcttc aggaagttca
    22741 agtgtgtaac cttctgcaat ttgtagcact ggaccaaccc cttttagaag attgagacgt
    22801 accattgtta ctggcatatc ccccttcgtc aagaaacgag ttgagaatcc tcctccacgg
    22861 aagtactcgc ggtttgctgg tgggaagtct gtattttcaa gcatagcctg tacttcactt
    22921 tcttccaact cccagaatgg tttcataaca ggtttgccat ctcgagtagc ttgacctgta
    22981 ccatccaatg tacaagaacc agagttgatt agatgtaaga agccagctgc agcacaaccc
    23041 tctaaagtat gtcccgttac acgtttaaca gcctctggac tccaataagt gcgcacatca
    23101 gcaaagattt gtggagtatt tgttaataga taattaaaga gcatagacac accatttagt
    23161 gaatcattct ctgtcgcaaa tacaaatggt tttcgaatac cattccagtc aaactgagta
    23221 ttgaggaaag tttccataaa atctccattt ggaaaatggt ctgtccactg acgttgacct
    23281 tggaaaccag ctactaaagc atggtgacca accgcttctt cctcaaaacc aagttcagca
    23341 agccttgggt taccaaccat taagtcacgt ccaatcatga acatcttaat aacaaattcc
    23401 cattgttttt ctttctcttc tttagaaaga atcaaatcct cacgatttcg gtcaacccct
    23461 tctttgatat gttcttttac ccaaaccata gcacgttcga actcttctgg gtcataaata
    23521 ccacggtcca tacggcgcgt gaactccgtc atatctaccg attcatttcg cattcctaag
    23581 tattcttgga agaaatctgg atttacaata gaaccgccaa tccccatcga aacactaccc
    23641 attgataggt aagcagtgtc tctcatcaag ccagttgcaa gagctgcacg cgcataacgt
    23701 aaaagttttt ctttgacatc ttctggaata tctgtatcat tagcttcctg aacatctcta
    23761 ccataaatcc caaaggctgg aatccctttt tgagcatgtg aagctagtac agctgcaaga
    23821 tagacagctc ctgggcgttc tgtcccatta aatccccaaa tagcatgagg aatatctgga
    23881 gacatatcca tagtttcact accataacac cagcatggtg taactgtaat tgttgcgcaa
    23941 acatttgatt ttttaaacaa ctcatgggaa gctgcagcct ctggaacacg accaatggta
    24001 gatggagaaa tcacacattc cacaggttcc ccatctggat atttcaatgt gcttgaaatc
    24061 aaatctgcca cacttttagc catgttcatt gtttgtactt caagtgattc gcgtacacct
    24121 tgacgacgac catcaatagt cggacgaatc ccaatacgtg gatgttgaat catactattt
    24181 tcctcttatt tttctgtttc tttcatacta ccgatgataa tttttaaaat tacttataag
    24241 tataaacctc tacctctgcc aaacttaaag gaattcctgc gtttctcaaa gaaattctaa
    24301 ccttttttcc cttcagccct tttaagtcta tggatagatt attgctttct aaactgtcaa
    24361 tatgttgttt aaaaacttca tgattatttg aatcatatat aataatatca aaatttgata
    24421 atctctgaat ttcagcatct gttctattat aaataattaa cttttctaat tcttcggttt
    24481 gtgctaaatc tatctcccac catgaaggag aatctccttt ggtatgagtc actgaatgat
    24541 gaccataatc tccgttttta tttccatcaa ctgctagacg agaaaaacca ttgtaatccg
    24601 ttgaactctg tcgagtttct ttggttaatg caatattaga aagtttcttc ggagttctct
    24661 ttgaaccata ggcttcaact tccgctaaac ttaacggaat agctgctgat tttaattcta
    24721 ttttgactag cttagcccct acagaaggta cttttaaaga taacaaacca tcaactactt
    24781 tatcaaaatg tcttctaaaa acttcttctc ctgatgaaga tagaaaaata acatcaaaat
    24841 tagataaacg ctgaggttcg gcatctgttc tattataaat atcaacttta gaaaccgtaa
    24901 actcttctcc cagatcgacc tgccaccaag cgttagaatc tgccttagta tgagtcaccg
    24961 aatgatgtcc gtaatctcca tctttattac catcaactgc taaagcagct acaccctcat
    25021 aattggttga actttgagta gctaccttat ttgtagagac tactttatct tctgttattt
    25081 tatctatatc ctcttcagat tgcttaccat ctgattctct aaaaacctct acttctgcta
    25141 aactcaaagg cactccactc gttagtaatt taactttaat ataccttgct cctttttctt
    25201 tgaaatctag actaacagat tcacccgaca aattattaac atgtttctta gcaacttcgt
    25261 ttctattatt gtcatataga atcacatcaa aattagatag acgttgagtc tcagcatctg
    25321 tgcgattata aattttaaca agcccaactt tatccatttt tttcaaatcg acttcccacc
    25381 aagagggatt atctgcccta gtgtgtgtta ccgaaccaga gttaaaatta ccatttctgt
    25441 taccatccac agctctatta gggtctccat tgtaatctac agaactttgt gttgttggtt
    25501 ttgcatatgc tatattcaaa ttaccatcat taaatttatc tggtgttggg aaagggactg
    25561 ggcctgtccc ttcagtattt atagacatct ctaccattcc attatgatta accgtaatgg
    25621 tataaacatg ggtattctca tcccaatttt ctgtataagt ataatgattt ttatcgccac
    25681 ttatatttat ctgaggttta tgaccagtat gcccttttaa tgtaagtgtt gttgtcctaa
    25741 agtcattatc tacaggattg atggaataat ttttgcttat ccagttcgct aactctaatt
    25801 cttctttctt ccaacttttt gatgcatcaa aatttcctga taatgcccac atagctgtct
    25861 tatctgtcct gtaatt
//
LOCUS       DAVBEO010000029        25712 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 009
            SAMEA1678075-rid20185393.denovo.029, whole genome shotgun sequence.
ACCESSION   DAVBEO010000029 DAVBEO010000000
VERSION     DAVBEO010000029.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678075
            Sequence Read Archive: ERR226392
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 25712)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25712)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980207.1
            Genome Coverage       :: 150x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:50:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 72 of 147
            Pseudo Genes (incomplete)         :: 72 of 147
            Pseudo Genes (internal stop)      :: 42 of 147
            Pseudo Genes (multiple problems)  :: 32 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25712
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678075-rid20185393.denovo.029"
                     /strain="KS 009"
                     /db_xref="taxon:1313"
     gene            <1..91
                     /locus_tag="VQ543_001219"
     CDS             <1..91
                     /locus_tag="VQ543_001219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS630 family transposase"
                     /protein_id="HET2611942.1"
                     /translation="WAHIKKHLKKVLPSCNTFYEALLSCSCFN"
     gene            48..437
                     /locus_tag="VQ543_001220"
     CDS             48..437
                     /locus_tag="VQ543_001220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001235657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HET2611943.1"
                     /translation="MPFTRLFCLVLVSIDYINCLSETADKNWHKSDRIFVTNTGKTVH
                     SSILSKSLQRANERLKKPIPKHLSPHIFIHITISILSENKIPLKTITDRVGHPDSEVT
                     NSIYTHVTKNMKDEAINVLDKVMKKIF"
     gene            complement(929..1339)
                     /locus_tag="VQ543_001221"
     CDS             complement(929..1339)
                     /locus_tag="VQ543_001221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001124848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2611944.1"
                     /translation="MPKKKIERISVIHREKILWLKWYFMRDKEKPKYSVLECKMFDAA
                     KNKDMLAYKKYATIKQITDIRVQTSEDDILTAIKEVYVYNHMNVIGACQRILFVSQSP
                     AYNKLNKWFETYSDLYFSIIPLPNMGAYHELVDS"
     gene            complement(1357..1734)
                     /locus_tag="VQ543_001222"
     CDS             complement(1357..1734)
                     /locus_tag="VQ543_001222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001233892.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2611945.1"
                     /translation="MRKYLKEIKELQELKELLSSRNTPEVIIVEGNDDLGEFFQVDGE
                     LFSDIELLENLKKWREWEVQVIVDDWCNRGLNEYETGILYFPKHEDKMDYIRFNKGLE
                     PLYHALDEPYTTISKSEWLKLLD"
     gene            complement(1676..2104)
                     /locus_tag="VQ543_001223"
     CDS             complement(1676..2104)
                     /locus_tag="VQ543_001223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000918209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein"
                     /protein_id="HET2611946.1"
                     /translation="MAGNENDGLTSKQIKFIDAMLTEPTIDKACQKAGVSRATGHKYL
                     KVAAVKKTLRLKQDEMMDKTTQMLYLASSNAVSVLNDIMMDAKINPFIRTQAAKTILE
                     QSYKTHEIFGVVRQIEELRLEIEEVSKGDQRVTRTQGIIK"
     gene            complement(2148..2753)
                     /locus_tag="VQ543_001224"
     CDS             complement(2148..2753)
                     /locus_tag="VQ543_001224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2611947.1"
                     /translation="MTFTTIKDDIKAFGKKKHGYMTGYIAKQEELHKQLQNGMIGEKY
                     AKDQLEAYKLEGDTYSRDTYNKIHAEIEKQHDLELEALKEKELSVTADDVAELTLLAS
                     MKMTKDELLGYFEKYKNKPLAIKKLWSIAEQYPEIAINLELFNAEQALESLILFFKRQ
                     LSYCHYSLLINGDKIQAVTTEMVVNSDAPELDRRLDEYLNK"
     gene            complement(2843..3016)
                     /locus_tag="VQ543_001225"
     CDS             complement(2843..3016)
                     /locus_tag="VQ543_001225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2611948.1"
                     /translation="MTENKDNKLLEMMEKGFVLYSKNGIIKYIEIPDHGSIKLKAQDG
                     QLVYKEVTTGEQC"
     gene            complement(3615..4511)
                     /locus_tag="VQ543_001226"
     CDS             complement(3615..4511)
                     /locus_tag="VQ543_001226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000838906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HET2611949.1"
                     /translation="MKSLQSSLGNIETFKLDELCPKHEIQLTQIKGERHVVVGWNENG
                     EVIKEVRCIPPYCEQCQEEQKKQDEEDAIADNLNAKLYLQTYNVLMSNKSYVADEFKT
                     KTFDDFNAVTSEEKRFLEFAKGQVQKYLDGMRGNTLITGGTGIGKTLLSVAIAKGINE
                     GYKTKGEPKSVLFVSLTEMIKQIKEGWNYGKGATLTEFEATELMKSVDYLIIDDLGAK
                     NAVIKPKSDWEQDLLFDVLNNRENTIFNTNLDSDELKIVYNERNYSRILKGLEGNTFK
                     AFTIKDKRYSINQLKNKVKQLK"
     gene            complement(4523..5332)
                     /locus_tag="VQ543_001227"
     CDS             complement(4523..5332)
                     /locus_tag="VQ543_001227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HET2611950.1"
                     /translation="MAKTKVYFWLKIDKKFFDNIFIKRLKTVPGGYTMTVIYIRLMLE
                     SLESDCILYYEGYFNNLKEELALKLDVSEDDIDMTMAYFTKCGLIQIDEDKNAELPQA
                     KAMVMSETNWASYKREQRKKGKLEEVQPSLTFSNSCPTEIEKELEIEVDKEQSPTPST
                     INQDFVNLYKSFEAETGKALSPLQIQELQYMLEDFSPELIHEALKEAVSQGKANFAYI
                     KAILNRWKQDNLLTVELVRNSRAAREAKKQQTNQLEPTSYEDWIPTQEKPF"
     gene            complement(5407..5622)
                     /locus_tag="VQ543_001228"
     CDS             complement(5407..5622)
                     /locus_tag="VQ543_001228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001003747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2611951.1"
                     /translation="MNELDISNTQAVFVTVILIGLLLYLNHRDRKKSAQLERENQQTI
                     ETPSEDLNPDYGRYIQLAGVDVWGRIE"
     gene            complement(5624..5824)
                     /locus_tag="VQ543_001229"
     CDS             complement(5624..5824)
                     /locus_tag="VQ543_001229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000171238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2611952.1"
                     /translation="MTLDLDNMTQAEFDEAMAEIQLQSPNIFQLISDFVNKKVTSVEI
                     DDLLNMKRAEQVAYIKNYKARA"
     gene            complement(5821..6012)
                     /locus_tag="VQ543_001230"
                     /pseudo
     CDS             complement(5821..6012)
                     /locus_tag="VQ543_001230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841301.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(6001..6291)
                     /locus_tag="VQ543_001231"
                     /pseudo
     CDS             complement(6001..6291)
                     /locus_tag="VQ543_001231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424675.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Rha family transcriptional regulator"
     gene            complement(6461..6613)
                     /locus_tag="VQ543_001232"
     CDS             complement(6461..6613)
                     /locus_tag="VQ543_001232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000706985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2611953.1"
                     /translation="MKIVTFKPTKQIDGGFYLPGIDILFVSDKADAKSTEDVILFISR
                     NGLNKS"
     gene            complement(6624..6890)
                     /locus_tag="VQ543_001233"
     CDS             complement(6624..6890)
                     /locus_tag="VQ543_001233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015604664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2611954.1"
                     /translation="MEILSKEIQLQGLQLLKQTLETLVELEKQRSSKLDLISRKELMD
                     LLGISATTLDNWEDLALKRYQTPMDGAKKVFYRLSDVYLFLAIK"
     gene            complement(7101..7283)
                     /locus_tag="VQ543_001234"
     CDS             complement(7101..7283)
                     /locus_tag="VQ543_001234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012027461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HET2611955.1"
                     /translation="MLITLSLAEKVRIKRARLQLTKKAVSEQLGIKSQTLTKVENGNY
                     DASKRIYESVMTWLVE"
     gene            7345..7848
                     /locus_tag="VQ543_001235"
     CDS             7345..7848
                     /locus_tag="VQ543_001235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET2611956.1"
                     /translation="MYKMNRIKQLRKENNLTQRELANETKIPYRTIQRWENGETDIKS
                     DAAQVLADYFGVSIPHLLGYSDLIADTDSDIKAMAYSHLLTFVDEKQIKEFEKEFIRA
                     NDNSDTFGDLGSGEKALEKYYQALCYLVPPFRDILARYSFLSLDEKKSVYNIIVGLSN
                     NLSKENK"
     gene            7922..9085
                     /locus_tag="VQ543_001236"
     CDS             7922..9085
                     /locus_tag="VQ543_001236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015604661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HET2611957.1"
                     /translation="MNIIEKIKKNGQRVYYASVYLGVDQLTGKKARTTVTATTKKGVK
                     VKARDAINTFAANGYTVKDKPTITTYNELVKVWWDSYKNTVKPNTRQSMDGLVRVHLL
                     PVFGDYKLSKLTTPILQQQVNKWADKANKGEKGAFANYSLLHNMNKRILKYGVAIQVI
                     QYNPANDVIVPRKQQKEKAAVKYLDNKELKQFLDYLDTLNQSNYENLFDVVLYKTLLA
                     TGCRISEALALEWSDIDLESGVISINKTLNRYQEINSPKSSAGYRDIPIDKATLLLLK
                     QYKNRQQIQSWKLGRSETVVFSVFTEKYAYACNLRKRLNKHFDAAGVTNVSFHGFRHT
                     HTTMMLYAQASPKDVQYRLGHSNLMITENTYWHTNQENAKKAVSNYETAISNL"
     gene            complement(9239..10543)
                     /gene="eno"
                     /locus_tag="VQ543_001237"
     CDS             complement(9239..10543)
                     /gene="eno"
                     /locus_tag="VQ543_001237"
                     /EC_number="4.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopyruvate hydratase"
                     /protein_id="HET2611958.1"
                     /translation="MSIITDVYAREVLDSRGNPTLEVEVYTESGAFGRGMVPSGASTG
                     EHEAVELRDGDKSRYGGLGTQKAVDNVNNIIAEAIIGYDVRDQQAIDRAMIALDGTPN
                     KGKLGANAILGVSIAVARAAADYLEIPLYSYLGGFNTKVLPTPMMNIINGGSHSDAPI
                     AFQEFMILPVGAPTFKEALRYGAEIFHALKKILKSRGLETAVGDEGGFAPRFEGTEDG
                     VETILAAIEAAGYVPGKDVFIGFDCASSEFYDKERKVYDYTKFEGEGAAVRTSAEQID
                     YLEELVNKYPIITIEDGMDENDWDGWKALTERLGKKVQLVGDDFFVTNTDYLARGIQE
                     GAANSILIKVNQIGTLTETFEAIEMAKEAGYTAVVSHRSGETEDSTIADIAVATNAGQ
                     IKTGSLSRTDRIAKYNQLLRIEDQLGEVAEYRGLKSFYNLKK"
     gene            10707..11153
                     /locus_tag="VQ543_001238"
     CDS             10707..11153
                     /locus_tag="VQ543_001238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000131081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YueI family protein"
                     /protein_id="HET2611959.1"
                     /translation="MTDLSKQLLEKAHGGLKINPDEQRRYLGTFEERVLGYVDIDTAN
                     SPQLEKGFLFILENLQEKAEPLFVKISPTIEFDKQVFYLKEAKETDSQATIVSEEHIT
                     SPFGLVIHSNAPVQVEEKDLRLAFPKLWEVKKEEPAKTSLWKKWFS"
     gene            complement(11150..12265)
                     /locus_tag="VQ543_001239"
     CDS             complement(11150..12265)
                     /locus_tag="VQ543_001239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000706318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HET2611960.1"
                     /translation="MKIVIAPDSFKESLTAQQVAEAIKRGFQQSIADVECLLCPVGDG
                     GEGTVDAIRHSLDLKEKWIQVTDPFGQKEAMRYFQKGELALFEVADLVGLGKIPLEKR
                     NPLQIQTCGIGELILHLISKGIKDIYIDVGGTASNDGGLGIAAGLGYQFYDRDGNVLP
                     ASGQSLLNLASVSTENCYKIPEGVQIHILADVVSPLCGHQGATYTFGNQKGRHPTMFA
                     VVDQAIQDFYEKFSPATLEIKGAGAGGGLAGGLCAFAQASIVSGIDTCLDLINFDKKV
                     SDADLVVVGEGRLDSQSFAGKAPIGVAKRTPVGVPVIAICGSLAEDLPPLPFENIQAV
                     FSILEKSEPLEDSLKNASLYLERTAANIGHLLNMCKI"
     gene            complement(12274..12603)
                     /locus_tag="VQ543_001240"
     CDS             complement(12274..12603)
                     /locus_tag="VQ543_001240"
                     /inference="COORDINATES: protein motif:HMM:NF019887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD hydrolase family protein"
                     /protein_id="HET2611961.1"
                     /translation="MERLAKSLGIAYFTANQLEVKEGLLTGKLVGQIISPQVKKETLE
                     KWRKKLKLSKERTVAIGDGGNNLLMLKSAELGIAFCSKEMLKKEIPHHVDKRDFLEVL
                     PLIDCLE"
     gene            complement(12557..12919)
                     /locus_tag="VQ543_001241"
     CDS             complement(12557..12919)
                     /locus_tag="VQ543_001241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IB family phosphatase"
                     /protein_id="HET2611962.1"
                     /translation="MSQVKGLCVLDVDGTLILEEVIDLLGREAGHEAEISQITSRAMR
                     GELVFESSLRKRVSLLEGLPILVFDNVFNSIHLSLNVPEFISILQKNGILVGLVSGGF
                     TPIVGEISKIPWYCLFHC"
     gene            complement(12978..14411)
                     /gene="glgA"
                     /locus_tag="VQ543_001242"
     CDS             complement(12978..14411)
                     /gene="glgA"
                     /locus_tag="VQ543_001242"
                     /EC_number="2.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen synthase GlgA"
                     /protein_id="HET2611963.1"
                     /translation="MKILFVAAEGAPFSKTGGLGDVIGALPKSLVKAGHEVAVILPYY
                     DMVEAKFGNQIEDVLHFEVSVGWRRQYCGIKKTVLNGVTFYFIDNQYYFFRGHVYGDF
                     DDGERFAFFQLAAIEAMERIDFIPDLLHVHDYHTAMIPFLLKEKYRWIQAYEDIETVL
                     TIHNLEFQGQFSEGMLGDLFGVGFERYADGTLRWNNCLNWMKAGILYANRVSTVSPSY
                     AHEIMTSQFGCNLDQILKMESGKVSGIVNGIDADLYNPQTDALLDYHFNQEDLSGKAK
                     NKAKLQERVGLPVRADVPLVGIVSRLTRQKGFDVVVESLHHILQEDVQIVLLGTGDPA
                     FEGAFSWFAQIYPDKLSTNITFDVKLAQEIYAACDLFLMPSRFEPCGLSQMMAMRYGT
                     LPLVHEVGGLRDTVRAFNPIEGSGTGFSFDNLSPYWLNWTFQTALDLYRNHPDIWRNL
                     QKQAMESDFSWDTACKSYLDLYHSLVN"
     gene            complement(14408..15547)
                     /gene="glgD"
                     /locus_tag="VQ543_001243"
     CDS             complement(14408..15547)
                     /gene="glgD"
                     /locus_tag="VQ543_001243"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase subunit
                     GlgD"
                     /protein_id="HET2611964.1"
                     /translation="MKIDKYSAILGNTVGFHNMSTLTDHRPVASLPFGGKYRLIDFPL
                     SSLANAGVRSVFGIFQQDNISSVFDHIRSGREWGLSTFLSHYYLGIYNTRVESSTVGK
                     EYYQQLLTYLKRSGSNQTVALNCDVLINIDLNQVFHLHSTTKEPITVVYKKLAKKDIS
                     EVNAILDVDETDHVLSHKLFDSKSTAETFNMSTDIFVVDTPWLIEHLEEEAKKEHPEK
                     LRYVLRDLAVKEGAFAYEYTGYLANIHSVKSYYQANIDMLESQKFYSLFSPNQKIYTK
                     VKNEEPTYYANTSKVRTSQFASGSIIEGQVANSVLSRNIHVHKDSLVKDSLLFPRVVI
                     GEGAQVEYAILDKGVEVEPGVVIRGTAEHPVVVKKGAKVTEDIHS"
     gene            complement(15537..16679)
                     /locus_tag="VQ543_001244"
     CDS             complement(15537..16679)
                     /locus_tag="VQ543_001244"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000787267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase"
                     /protein_id="HET2611965.1"
                     /translation="MKNEMLALILAGGQGTRLGKLTQSIAKPAVQFGGRYRIIDFALS
                     NCANSGIHNVGVVTQYQPLALNNHIGNGSSWGLDGINSGVSILQPYSASEGNRWFEGT
                     SHAIYQNIDYIDSVNPEYVLILSGDHIYKMDYDDMLQSHKDNNASLTVAVLDVPLKEA
                     SRFGIMNTDANNRIVEFEEKPAQPKSTKASMGIYIFDWQRLRNMLVAAEKSKVGMSDF
                     GKNVIPNYLESGESVYAYEFSGYWKDVGTIESLWEANMEYISPENALDSRNRQWKIYS
                     RNLISPPNFLGANAHVEDSLVVDGCFVDGTVKHSILSTGAQVREGAEVLDSVIMSGAI
                     IGQGAKIKRAIIGEGAIISDGVEIDGTDEVQVVGYNEVVGVATDED"
     gene            complement(16669..18597)
                     /gene="glgB"
                     /locus_tag="VQ543_001245"
     CDS             complement(16669..18597)
                     /gene="glgB"
                     /locus_tag="VQ543_001245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1,4-alpha-glucan branching protein GlgB"
                     /protein_id="HET2611966.1"
                     /translation="MDNREALKTFMTGENFYLQHYLGAHREELNGEYGYTFRVWAPNA
                     QAVHLVGDFTNWIENQIPMVRNDFGVWEVFTNMAQEGHIYKYHVTRQNGHQLMKIDPF
                     AVRYEARPGTGAIVTELPDKKWRDGLWLARRKRWGFAERPVNIYEVHAGSWKRNPDGS
                     PYSFAQLKDELIPYLVEMNYTHIEFMPLMSHPLGLSWGYQLMGYFALEHAYGRPEEFQ
                     DFVEECHTHNIGVIVDWVPGHFTINDDALAYYDGTPTFEYQDHNKAHNHGWGALNFDL
                     GKNEVQSFLISCIKHWIDIYHLDGIRVDAVSNMLYLDYDDAPWTPNKDGGNLNYEGYY
                     FLQRLNEVIKLEYPDVMMIAEESSSATKITGMKEIGGLGFDYKWNMGWMNDILRFYEE
                     DPIYRKYDFNLVTFSFMYVFKENYLLPFSHDEVVHGKKSMMHKMWGDRYNQFAGLRNL
                     YTYQICHPGKKLLFMGSEYGQFLEWKSEEQLEWSNLEDPMNAKMKYFTSQLNQFYKDH
                     RCLWEIDTSYDGIEVIDADNRDQSVLSFIRKGKKGEMLVCIFNMVPVERKDFTIGLPV
                     AGIYEEVWNTELEEWGGVWKEHNQTVQTQEGLWKDYEQTLTFTLPAMGASVWKIKRRL
                     KSTKTVTNKNQKGVENEK"
     gene            complement(19079..20503)
                     /locus_tag="VQ543_001246"
     CDS             complement(19079..20503)
                     /locus_tag="VQ543_001246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent glyceraldehyde-3-phosphate
                     dehydrogenase"
                     /protein_id="HET2611967.1"
                     /translation="MTRYQNLVNGKWKSSEQEITIYSPINQEELGTVPAMTQTEADEA
                     MQAARAALPAWRALSAIERAAYLHKTAAILERDKEKIGTILAKEVAKGIKAAIGEVVR
                     TADLIRYAAEEGLRITGQAMEGGGFEAASKNKLAVVRREPVGIVLAIAPFNYPVNLSA
                     SKIAPALIAGNVVMLKPPTQGSISGLLLAKAFEEAGIPAGVFNTITGRGSEIGDYIIE
                     HKEVNFINFTGSTPIGERIGRLAGMRPIMLELGGKDAALVLEDADLEHAAKQIVAGAF
                     SYSGQRCTAIKRVIVLESVADKLATLLQEEVSKLTVGDPFDNADITPVIDNASADFIW
                     GLIEDAQEKEAQALTPIKREGNLLWPVLFDQVTKDMKVAWEEPFGPVLPIIRVASVEE
                     AIAFANESEFGLQSSVFTNDFKKAFEIAEKLEVGTVHINNKTQRGPDNFPFLGVKGSG
                     AGVQGIKYSIEAMTNVKSIVFDVK"
     gene            complement(21047..23326)
                     /gene="pulA"
                     /locus_tag="VQ543_001247"
     CDS             complement(21047..23326)
                     /gene="pulA"
                     /locus_tag="VQ543_001247"
                     /EC_number="3.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000283081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pullulanase"
                     /protein_id="HET2611968.1"
                     /translation="MYNYPMRIHYHRKNGEYDTCSFVKSQDQRIDLLTYKEDYFGALF
                     SFEHPSSHVIESLNFVVHTGQTSKEYSIRFNHYPLLTEVWILEGDDRIYYSENPAIAS
                     PFYKNQNPFAFDKAINSASFDHHWGYQGELGCRVEDNQAHFSLWSPTATEVQVVVYES
                     AANDAPVWKTFEMKRGNSYSYNHKDNTIGVWSLDVEEDLVGKTYQYQVQFPHHQTLTR
                     DPYTIATSPDGKRSAILSHVEKQVENFEVKHGSEATWRLENPCKAVICEMHIRDLTKS
                     PTSGVDEHLRGTFLGAAQAGTVNQYGQSTAFDYIKKLGYNYVQLQPIADRHKEYDEDG
                     NVTYNWGYDPQNYNAPETSFSTNPDDPAQVIRDLKVMVQAYHDAGIGVIMDVVYNHTF
                     SVVDAPFQTTVPDYYYRMNPDGTFQNGTGVGNETASEHEMFRKYMIDSLLYWVQEYNI
                     DGFRFDLMGIHDVKTMQMIRQSLDEIDSNIILYGEGWDMGTGLAPYDKAKKDNAYQMP
                     NIGFFNDNQRDAVKGGEVYGAIKSGFVSGAATEPILAKAILGSRELGSYTHPNQVLNY
                     VEAHDNYNLHDLLATLHPDQSSEQIMRKVETATAMNLLMQGMAFMEIGQEFGRTKLVA
                     TGENGELTHDDRERAMNSYNAPDSVNQVNWNLINERQDSIEFIRQVIRLKTKTGAFSY
                     SSYDEIYHHVFVHSAIEHSGCLIYEVHGKEHLLVVVNAKSEPYQFENAGNLAMLVTNS
                     RSKEDNVLNDISLAVLSVL"
     gene            complement(23438..25396)
                     /gene="ligA"
                     /locus_tag="VQ543_001248"
     CDS             complement(23438..25396)
                     /gene="ligA"
                     /locus_tag="VQ543_001248"
                     /EC_number="6.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent DNA ligase LigA"
                     /protein_id="HET2611969.1"
                     /translation="MNKRMNELVALLNRYATEYYTSDNPSVSDSEYDRLYRELVELET
                     AYPEQVLADSPTHRVGGKVLDGFEKYSHQYPLYSLQDAFSREELDAFDARVRKEVAHP
                     TYICELKIDGLSISLTYEKGILVAGVTRGDGSIGENITENLKRVKDIPLTLPEELDIT
                     VRGECYMPRASFDQVNQVRQENGEPEFANPRNAAAGTLRQLDTAVVAKRNLATFLYQE
                     ASPSTRDSQEKGLKYLEQLGFVVNPKRILAENIDEIWNFIQEVGQERENLPYDIDGVV
                     IKVNDLASQEELGFTVKAPKWAVAYKFPAEEKEAQLLSVDWTVGRTGVVTPTANLTPV
                     QLAGTTVSRATLHNVDYIAEKDIRKDDTVIVYKAGDIIPAVLRVVESKRVSEEKLDIP
                     TNCPSCNSDLLHFEDEVALRCINPRCPAQIMEGLIHFASRDAMNITGLGPSIVEKLFA
                     ANLVKDVADIYRLQEEDFLLLEGVKEKSAAKLYQAIQASKENSAEKLLFGLGIRHVGS
                     KASQLLLQYFHSIENLSQADSEEVASIESLGGVIAKSLQTYFATEGSEILLRELKETG
                     VNLDYKGQTVVADAALSGLTVVLTGKLERLKRSEAKSKLESLGAKVTGSVSKKTDLVV
                     VGADAGSKLQKAQELGIQVRDEAWLESL"
     gene            complement(25489..>25712)
                     /locus_tag="VQ543_001249"
     CDS             complement(25489..>25712)
                     /locus_tag="VQ543_001249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001083019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HET2611970.1"
                     /translation="FFTQVQTKVESEFLGRVLSTIFTLAILFMPIAKGFMTVLPSVHL
                     SSFLIIGSGVIILSCISFIYVRTHFEKLI"
BASE COUNT         7629 a         5453 c         4415 g         8215 t
ORIGIN      
        1 atgggctcat atcaaaaagc acctcaaaaa ggtattacca agttgcaata ccttttacga
       61 ggctcttttg tcttgttctt gtttcaattg actatataaa ttgtctaagc gaaacagccg
      121 ataagaattg gcacaaaagc gaccgtattt ttgttaccaa tacaggaaaa acagttcata
      181 gttctatctt gagcaagtct ctccagcgag caaacgaacg ccttaaaaaa ccaattccca
      241 aacatctgtc ccctcacatc ttcatacaca tcactattag catcttatca gaaaataaaa
      301 ttcctttaaa aacaatcacg gacagggttg gtcatcccga ctctgaagtc actaattcca
      361 tctacaccca cgtcacaaag aacatgaaag atgaagcaat caatgtactg gataaagtta
      421 tgaaaaagat tttttaaaaa gttttgtccc ttttttgccc tctaaataca aaaatagccc
      481 ttcggataaa atccgagggg ctagaaacgt tgttaaatca acggccgaac ttttgaattt
      541 catggttcgg gataaaatag ttcactgaac tattttattt tttaaggtta tcataatatc
      601 aaatagttca attaaatacg ctaaattact aatatacttt ttaccttttt cattctaaaa
      661 tgtaaagtac aaacaattac aatatactag agggggagta aaaaaggtaa taaaattgac
      721 gagttcagca ggcaagggaa atagcacttt tcatggtgtt atttttttaa ttcagcaatg
      781 gagtagccgc ttaattgata gaaacaaaaa gcacctagtt tcctagatgc tagcacaata
      841 gcccggattc gaaccggaat ctcctcaatt aaggtgcaat ccctatatac tactcattgt
      901 gctttggttc attatatcat acaatcaact agctatctac caactcatga tacgctccca
      961 tattcggtaa tggaataata ctaaaataca aatctgagta agtttcaaac catttattca
     1021 gcttgttata ggctggcgac tgactaacaa ataatatccg ttgacaagct ccgataacat
     1081 tcatgtgatt atacacatag acctctttaa tggccgttaa aatatcgtct tcacttgtct
     1141 gtaccctaat atctgttatc tgcttaatcg tagcgtattt tttataagct agcatatctt
     1201 tatttttagc agcatcaaac attttacact caagaacact atacttaggt ttttctttat
     1261 ctctcatgaa ataccacttg agccataaaa ttttttctct gtgaattact gaaatacgtt
     1321 cgattttttt ctttggcatg attacctcct aaattattaa tctaatagct ttaaccactc
     1381 actttttgag attgttgtat aaggttcatc tagcgcgtga tataaaggtt ctaaaccttt
     1441 gttaaatcgg atatagtcca ttttatcctc atgctttgga aaatataaga ttcctgtttc
     1501 atattcattt agaccacggt tacaccaatc atcaacgata acctgcactt cccattcacg
     1561 ccacttttta aggttttcta aaagttcaat atcactaaat aactcaccat caacttggaa
     1621 aaattctccc agatcatcgt taccctcgac gatgataact tcaggcgtat ttctactact
     1681 taataattcc ttgagttctt gtaactcttt gatctccttt agatacttcc tcaatttcta
     1741 acctcaattc ttcaatttgt cttactactc caaaaatttc atgagtttta tatgattgtt
     1801 caagtatagt ttttgctgct tgagttctta taaaagggtt aattttggca tccatcataa
     1861 tatcattgag tacagaaaca gcattggatg aggctagata tagcatctgt gtagttttat
     1921 ccatcatctc atcttgtttt agtctcaatg tctttttaac agctgcaact tttagatact
     1981 tatgccctgt tgcccttgac acccctgctt tttggcacgc tttatctatc gttggctcag
     2041 taagcatggc atctatgaat tttatttgtt tagatgtaag gccatcattt tcatttcctg
     2101 ccatctatta cctcctcgtt atcaaaataa aggggttgct agcccctcta tttgtttaaa
     2161 tactcatcca aacgacggtc aagctcaggg gcatctgaat ttactaccat ttcagttgtt
     2221 acagcttgga ttttatcgcc gttgataagc aaactgtaat gacaatatga aagttgccgc
     2281 ttaaagaata agattagact ttctagcgcc tgctctgcat tgaataattc caagttgata
     2341 gcaatttctg gatattgttc agcaattgac caaagttttt taatagcaag aggtttgttc
     2401 ttgtattttt caaaataacc tagcaattca tcctttgtca tcttcatact agctaacaag
     2461 gtcagctctg ccacgtcatc agctgttacg ctgagttctt tttcttttaa tgcctctagc
     2521 tctagatcat gctgtttttc aatttctgca tgaattttat tataggtgtc cctagaataa
     2581 gtgtccccct ctaacttata agcctctagc tggtctttag cgtatttttc gcctatcata
     2641 ccattttgta actgtttatg taattcctct tgtttagcaa tgtagccagt catgtaccca
     2701 tgctttttct tgccaaaagc cttaatatca tccttgattg ttgtaaatgt catgttatcc
     2761 tccttacgaa aaaataaaag aggtatgaca aaagagcgtt aaactcaatt atcatacctc
     2821 tggtttttcc agtcagtatt tattaacatt gttctccagt ggtcacttcc ttataaacta
     2881 actgcccatc ttgagctttt agcttaatgc taccatgatc tggaatttca atgtacttta
     2941 ttataccatt ttttgagtat aaaacaaagc ctttctccat catttctaat aatttattat
     3001 ccttgttttc agtcatgaat ttctccttta tttcaagtgt cccaacgggt acggttgtaa
     3061 gctgagacat tttagggcta tctttgagcg acaaaaatgt cgaaaagtct tcagttcctg
     3121 tataaccgtt attagttttg tttgctactc atttttgagt cacaaatctg ttaagcaaaa
     3181 atgagtaata gctcgtaaga taagtaaatc taatacttgt attcctaaag cgttgatata
     3241 actgatattt tcaactatcc aacgctcttt actacccttt ttagtgtgct ttagctcatt
     3301 tttgagcttt tttgagcttt tttgagttcc attttgggaa tgcaaagcag gcgcgcaccg
     3361 tgcatgcttt tttcttgctc atagcctcac cctcagaagt ttgccgaccg agagcgtggg
     3421 gctttttatt tttgtataat taaaaacagc tgcacaattt ttgtacagct acgaccgagg
     3481 caggggcgac ctgccgtact ttacactaga taatatcatc taggtagtcc aactgtattt
     3541 tatcatatta aaggctacat tacaatttct caccctgtga agagtgtcta tttttgttta
     3601 ggtttgtaag tcgattactt caactgcttt accttatttt ttaactgatt aattgagtat
     3661 cgcttatctt tgattgtgaa agccttaaaa gtgttaccct caagaccttt tagaatacgg
     3721 ctataattcc gctcgttgta tactatcttg agttcatcgc tatcaagatt tgtattaaat
     3781 atagtatttt ctcgattatt cagtacatca aaaagtaaat cctgctccca atcgctctta
     3841 ggtttaataa cagcattttt tgcacctaaa tcatcaataa ttaagtaatc aacagacttc
     3901 atgagttcag tagcttcaaa ctctgtaagt gttgcacctt taccataatt ccacccctct
     3961 ttaatttgtt tgatcatttc ggttaggctt acaaaaagca cactcttagg ttctcctttt
     4021 gtcttatacc cctcatttat acctttggca atagcaactg ataaaagtgt ttttccaatc
     4081 cctgtacctc ctgtgataag cgtatttccc ctcatgccat caagatattt ttgtacctga
     4141 ccttttgcaa attctaaaaa tcgcttttct tctgatgtta cagcattaaa atcatcaaaa
     4201 gttttagttt taaactcatc tgctacatag ctcttattgc tcatcaacac attataagtt
     4261 tgcagatata gtttagcatt caaattatca gcaatcgcat cttcttcatc ttgctttttc
     4321 tgttcttctt ggcattgttc acaatagggt gggatacagc gaacttcttt tattacctct
     4381 ccgttctcat tccaccccac tactacatgt ctttctcctt tgatttgtgt tagctgtatt
     4441 tcatgcttag gacacaattc gtctagttta aatgtctcaa tatttcctaa actagattgt
     4501 aatgatttca ttttctgacc tcctaaaatg gtttttcttg tgttggtatc caatcttcat
     4561 agctggtagg ctctagttga ttggtttgct gttttttagc ctcacgcgct gccctgctat
     4621 ttctaacaag ttccaccgtc aataaattgt cctgtttcca acggttaagg attgccttga
     4681 tgtatgcaaa gtttgcttta ccctgactga cagcctcttt taacgcctca tggataagct
     4741 ctgggctaaa atcttctagc atatactgca attcttgaat ctgtaacggt gacaatgctt
     4801 tacctgtctc agcttcaaaa gatttataga gatttacaaa atcttgattg atggtagagg
     4861 gagtgggtga ttgttcttta tctacttcta tctctaattc tttctctatc tctgttggac
     4921 atgagttgga aaatgtcaaa gatggttgga cttcttccaa ttttcctttt tttcgttgtt
     4981 cacgtttata actcgcccag tttgtttcac tcataaccat agcttttgcc tgtggtagtt
     5041 ctgcgttttt atcttcgtca atctgtatta aaccgcattt tgtaaagtat gccatggtca
     5101 tatctatatc atcttctgat acatctaatt ttagggctaa ctcttccttg agattgttaa
     5161 agtagccctc atagtataaa atacagtcac tttccaagct ctctaacatg agcctaatat
     5221 aaataactgt catagtgtac ccaccaggta ccgtctttag tctcttgata aaaatattat
     5281 caaaaaattt cttatcaatt tttagccaaa aatagacttt tgtttttgcc atcgtcctct
     5341 cccttgctca tttataattc tctaccttga ttagtcttaa tactcgcttg tcattcattg
     5401 ttagactcat tcaattcttc cccatacgtc tacccctgca agctggatat atcgcccata
     5461 atcagggttt aaatcctcgc taggtgtttc tatcgtctgt tggttttctc gctccagttg
     5521 ggcgcttttt ttgcggtctc ggtggtttaa ataaagcagt aagccaatca aaatcacggt
     5581 aacaaaaacc gcctgtgtat tgcttatatc tagttcattc atgttatgcc ctcgctttgt
     5641 aattcttgat gtatgccact tgttcagctc gcttcatatt caacaagtcg tctatttcca
     5701 cactggttac ttttttattt acaaaatcag aaatcagttg aaaaatgttt ggactttgta
     5761 gctggatttc agccattgcc tcatcaaatt ctgcttgtgt catgttgtct aaatctagtg
     5821 tcattgcatt gcctcctcaa acttctctat aagacaactt ttatttgctt tctgagttcc
     5881 atttttagag ttaaaaagaa tatattttaa ggttacagta gcctctaaat actccttttc
     5941 agcatgctct atatacgcct gttgctctgc ttcgttctca aaaaagtgct tagcttagcg
     6001 tttaaagaat gctttgacta ggtttagttt gaattgccgt actgcttcgg tattctttag
     6061 ataagtgatc agcaaagtag cctgttgctc gttcagaata taggattttt taggttgtcc
     6121 tctagtgtct aatttatgga ttttaaatcc aagtattccc aactcttcaa agtcaacctt
     6181 attttctctt attaagcgtg tgatagtgtg gtgttgtacg tcagcacatt cagcgatgat
     6241 ctcgcttgtg gtatacggct ctttcttgcc gtccatgtag actagttcca ttatggttct
     6301 acctcctgta taaatttagc tagcttactt tttaattgtc tcctctagcc ctttttagcc
     6361 tctacaacgg ttttggctaa cgtgttagag gcttttataa cggcctgtat agctgtctct
     6421 atttcctccg tggaatagta gctttgtttt ctaatatcat ttaagacttg tttaacccat
     6481 ttcttgaaat aaataaaatt acatcttctg tactcttggc atctgcttta tctgagacaa
     6541 atagaatgtc aatgcctggt agataaaacc caccgtctat ttgtttagtt ggtttgaaag
     6601 taactatttt catttcataa ctcctatttt attgctaaaa ataaatacac atctgacaga
     6661 cgatagaata ctttcttagc tccatccatc ggggtctgat atcgtttaag agcaagatcc
     6721 tcccagttat caagggttgt agcacttata cctagcagat ccattaattc tttacgagaa
     6781 attaaatcta acttactaga tcgttgtttt tctagctcaa ctaaagtttc aagagtctgt
     6841 ttaagaagct gtaaaccctg taactgtatt tctttagaca gaatttccat ttatatcctc
     6901 cattttcctt tttataaatt aagttgtctt tttcctctaa ttttgataaa ataagaagag
     6961 attatttagc aaagggggtt gtccctttgc taaataccta acaaaaccac gcgccttgcc
     7021 tttgcttgag ttttgttatt tttccttagc cgtgtacgtt ggtttggtcg cctgtacatg
     7081 gctttttact tgcgttaaat ttattctact agccaagtca tcacgctctc atagatacgc
     7141 ttagaggcat catagtttcc attctcaact tttgttagtg tttgagattt aatacccaac
     7201 tgctccgata ctgctttttt ggttagctgt aatcttgcac gcttgatacg tactttttca
     7261 gcaagtgata gtgtaatcaa cattggtttc acctcccttt tttctccatt tttggcattt
     7321 tgtgttataa tctctttaga aaggatgtat aagatgaata gaattaagca attacgaaaa
     7381 gaaaataatc ttactcaaag agaacttgct aatgagacta aaatccctta tagaaccata
     7441 caacgttggg agaatgggga aactgatata aaatccgatg ctgctcaggt acttgctgac
     7501 tattttggag tatcaattcc tcacttacta ggttatagcg atttgatagc agatacagat
     7561 agtgatatta aagcaatggc atactcacat ctactaactt ttgtagatga aaaacaaatc
     7621 aaagaatttg aaaaagagtt cattcgtgca aacgataata gtgatacttt tggtgattta
     7681 ggaagtggtg aaaaggcgtt agaaaaatac tatcaagcat tatgctattt agttcctcct
     7741 tttagggata tattggctag gtatagcttt ttgtcactag atgaaaaaaa atcagtctat
     7801 aatattattg ttggtttaag taacaactta tcaaaagaaa ataaataact ttaaacatca
     7861 tgtataaata cctaacaaaa ccacgcgcct tgcctgctga tggaaagaaa ggtacaaata
     7921 catgaatatc atagagaaaa ttaaaaagaa tggccaaaga gtttattatg ctagtgttta
     7981 tctaggcgtt gaccaactaa cgggcaaaaa agcccgtaca actgttacag caaccactaa
     8041 aaagggcgtt aaagtaaaag cgcgtgatgc gatcaatact tttgctgcta atggctatac
     8101 agttaaagat aagccgacaa ttacaacata caatgagctt gtaaaagttt ggtgggatag
     8161 ttacaagaat acagttaagc caaatactcg ccaatccatg gatggattgg ttagagtgca
     8221 tttattgcct gtatttggcg attacaagct atctaaactt actacgccta ttcttcaaca
     8281 gcaagtaaac aaatgggctg acaaggcaaa taaaggcgaa aaaggggcat ttgctaacta
     8341 ctccttgctc cataacatga ataagcgtat tttgaaatat ggcgtagcta tccaggtaat
     8401 acaatacaac ccagctaatg atgtcatcgt tccacgcaaa cagcagaaag aaaaggctgc
     8461 tgtcaaatac ttagacaaca aagaattaaa acagtttctt gattatttag acactctgaa
     8521 tcaatcaaat tatgagaact tatttgatgt tgtcctgtat aagactttat tggccactgg
     8581 ttgccgtatt agtgaggctc tagctcttga atggtctgat attgacctag aaagcggtgt
     8641 tatcagcatc aataagacac taaaccgcta tcaggaaata aattcaccta aatcaagcgc
     8701 tggttatcgt gatataccaa tagacaaagc cacattactt ttactgaaac aatacaaaaa
     8761 ccgtcaacaa attcagtctt ggaaattagg ccgatctgaa acagttgtat tctctgtatt
     8821 tacggagaaa tatgcttatg cttgtaactt acgcaaacgc ctaaataagc attttgatgc
     8881 tgctggagta actaacgtat catttcatgg tttccgccat acacatacta ctatgatgct
     8941 ctatgctcag gctagcccga aagatgttca gtatagatta ggccactcta atttaatgat
     9001 cactgaaaat acttactggc atactaacca agagaatgca aaaaaagccg tctcaaatta
     9061 tgaaacagct atcagcaatt tataaaaaat aagggtgacc catttccggg ctaccctctt
     9121 actataccaa aaattagtag gggtagtaaa aagggtatta aattataaaa agcactaagg
     9181 gaaagcgccc caaagtgctt atttcaaagg ctttatagcc tataatcaca taaggagatt
     9241 attttttaag gttgtagaat gatttcaatc cacgatattc agctacttca ccaagttggt
     9301 cttcgatacg aagcaattgg ttgtatttag cgatgcggtc tgtacgtgaa agtgaaccag
     9361 tcttgatttg tcctgcgtta gttgcaactg caatatcagc gattgttgaa tcttcagttt
     9421 cacctgaacg gtgtgataca acagcagtgt aaccagcttc tttagccatt tcgatagctt
     9481 caaaagtttc agtaagagta ccgatttggt taactttgat aaggattgag ttagcagcac
     9541 cttcttggat accacgtgca aggtagtcag tgtttgttac gaagaagtcg tcaccaacaa
     9601 gttgtacttt cttaccaaga cgttcagtaa gagctttcca accatcccag tcgttttcat
     9661 ccataccatc ttcaatagtg atgattgggt atttgttaac caattcttca aggtagtcga
     9721 tttgttctgc agatgtacga acagcagcac cttcaccttc aaatttagtg tagtcgtaaa
     9781 ctttacgttc tttatcgtag aattctgatg aagcacagtc aaatccgata aatacgtctt
     9841 tacctggtac atatccagca gcttcaatcg cagcaaggat agtttcaaca ccatcttcag
     9901 ttccttcgaa acgaggagcg aatccacctt cgtcacctac ggcagtttcc aaaccacgtg
     9961 atttaaggat tttcttaaga gcgtggaaga tttcagcacc gtaacgaagg gcttctttaa
    10021 atgttggcgc accaactggc aagatcatga actcttggaa agcgattgga gcgtcagagt
    10081 gagaaccacc gttgatgatg ttcatcattg gagttggaag aactttagtg ttgaatccac
    10141 caaggtagct gtaaagtggg atttcaaggt agtcagcagc agcacgagct acagcgatag
    10201 acacaccgag gattgcattc gcacccaatt tacctttgtt aggagtaccg tcaagtgcga
    10261 tcatagcacg gtcaatagct tgttgatcac gtacatcgta gccaatgata gcttcagcaa
    10321 tgatgttgtt tacgttgtca acagcttttt gtgtaccaag accaccgtaa cgagatttgt
    10381 caccgtcgcg aagttcaact gcttcgtgtt caccagtaga agctcctgat ggaaccatac
    10441 cacgtccgaa agcacctgat tcagtgtaaa cttctacttc aagtgttggg ttaccgcgtg
    10501 agtctaggac ttcgcgagcg taaacatcag taataattga cattttttac tctccttatg
    10561 agttaaattt tttacacctc tataatacct taaaacccct cctttttcaa gaaaaaacgt
    10621 tatctttgtg caacttttcc ttaactttat aaagtaatcg ctttcttttg tctgttttat
    10681 tctaactttt atgatatact gttttcatga cagatttatc aaaacaatta cttgaaaaag
    10741 ctcatggtgg gttaaaaata aatccggatg agcaaagacg ctatcttggt acttttgagg
    10801 aaagagttct tggatatgta gatattgaca cagcaaatag ccctcagtta gaaaaaggct
    10861 ttttatttat tttagaaaac cttcaggaaa aagcagagcc actatttgtg aagatttcac
    10921 caactatcga atttgataag caagttttct acttaaaaga agcaaaagaa actgatagtc
    10981 aagccaccat agtatctgaa gagcatatta cttctccttt tggcctggtt attcatagca
    11041 atgcaccagt tcaagtagaa gaaaaagacc ttcgacttgc ttttccaaaa ctttgggaag
    11101 ttaaaaagga agaaccagcc aaaacatcct tatggaagaa atggtttagc taaatcttgc
    11161 acatatttaa taagtgccca atattggcag ccgtgcgctc cagatagaga ctggcatttt
    11221 tcaaactatc ttctaaaggt tcacttttct ccaaaataga aaagacagct tggatatttt
    11281 caaatggtag gggaggtaaa tcttcagcaa gactaccgca aatagcaata acaggaactc
    11341 caacaggggt tctttttgca acacctatag gcgctttccc agcaaagctt tgactatcaa
    11401 gtcttccttc tccaacaaca accaagtcag catctgaaac tttcttatca aagttgatta
    11461 agtccaagca ggtatcaatt ccagacacga tacttgcctg agcaaaagca cacaaaccac
    11521 cagcaaggcc tccacctgct cctgctcctt taatttctaa tgttgcaggt gagaattttt
    11581 cataaaaatc ttggatcgcc tgatctacga ctgcaaacat agtcggatgt cgaccttttt
    11641 gattgccaaa agtataagtc gcaccttgat gaccacataa gggacttacg acatctgcta
    11701 aaatatgaat ttgaacacct tcaggaattt tatagcaatt ttctgttgaa acagaagcta
    11761 agtttaataa ggattgaccg gaagcaggca agacatttcc atccctatca taaaattgat
    11821 aacctaaacc agcagcaatc cccagtcctc catcattact ggccgtgcca ccaacatcga
    11881 tataaatatc tttaatccct ttagaaatga gatggagaat caactctcca ataccacaag
    11941 tttggatttg aagtggattt cgtttctcta gcggaatttt tccaagacca accaagtcag
    12001 ctacttcaaa tagtgccagt tccccttttt gaaaatagcg catggcttct ttttgtccaa
    12061 aagggtctgt cacttggatc catttttctt ttaggtcaag agaatgtcgg atagcatcta
    12121 cagtaccttc tcccccatca ccaacagggc agaggagaca ttctacatct gctatcgatt
    12181 gttggaagcc tctttttatt gcttcagcta cctgttgagc tgtcaagctt tccttaaacg
    12241 aatccggtgc aattacaatc ttcatatttt ccctcattct aaacagtcaa tcaaaggaag
    12301 aacttctaaa aaatccctct tgtcaacatg atgtggtatt tcttttttga gcatttcttt
    12361 ggaacaaaag gcgattccta actccgccga cttcaacatt aatagattat tgcccccatc
    12421 accgattgcc accgttcttt ctttagaaag ttttagtttc tttctccatt tttccagagt
    12481 ttcttttttg acctggggac ttataatttg tccaactaat tttcctgtta aaagaccttc
    12541 tttgacttca agctggttag cagtgaaata ggcaatacca agggattttg ctaatctctc
    12601 caactattgg tgtaaatcca ccagacacca gaccaactag gataccattc ttttggagaa
    12661 tagagatgaa ctctgggaca tttagcgata gatgaattga gttgaagacg ttatcaaaga
    12721 ccaaaatagg aagaccttcc aacaaggaca ctctttttct taaactgctt tcaaagacca
    12781 actctcctcg cattgctcga cttgtaatct gcgaaatttc tgcctcatga cctgcctctc
    12841 tccctaaaag atcaatcact tcttctagga ttaaggttcc atctacatcc aaaacacaca
    12901 agccttttac ttgagacatc agttctcctc tctaaacagc ctaaaaatcg tatgaagtca
    12961 tcatacgatt ttatctatta attaactaaa ctatggtaca agtcaaggta tgacttgcag
    13021 gctgtatccc atgagaagtc actctccata gcttgttttt gtaggtttct ccaaatgtct
    13081 ggatggtttc tatacaagtc caatgctgtt tggaaagtcc aatttaacca ataaggagat
    13141 agattgtcaa agctaaagcc agtaccgctt ccttcgattg gattgaaagc gcgaactgta
    13201 tctcgcaagc ctccaacttc atggaccaat ggcaaggttc cataacgcat agccatcatt
    13261 tgagacaagc cacacggttc aaaacgactt ggcatgagga agaggtcaca agcagcgtag
    13321 atttcctgag caagtttgac atcaaaagtg atatttgttg atagcttgtc tgggtaaatc
    13381 tgagcaaacc atgagaaagc tccttcaaag gctggatcgc cagttcccaa aagaacaatc
    13441 tgaacatctt cttgcaagat atggtgaaga ctttcgacca ccacatcaaa acctttttga
    13501 cgtgtcaaac gagaaacaat tcccaccagt ggaacgtctg ctctaacagg caagccaact
    13561 ctttcttgca attttgcctt atttttggct ttcccagaca aatcttcctg attgaaatga
    13621 tagtctaaaa gagcatccgt ctgaggatta taaagatcag catcaatccc attcacgata
    13681 ccagatactt taccagactc cattttaaga atctgatcca aattacatcc aaactgacta
    13741 gtcataattt catgagcata gctaggtgaa acggttgaaa cacggttcgc atagagaata
    13801 cctgccttca tccagttcag acagttgttc catcgaaggg tgccatcagc gtaacgttca
    13861 aagccaactc caaacaaatc acccaacatt ccttctgaaa attgtccttg gaattctaaa
    13921 ttatgaatgg ttaaaactgt ttcaatgtcc tcataggctt gaatccaacg gtatttttcc
    13981 ttcaacaaga aaggaatcat agctgtatgg tagtcatgaa catggagaag atcaggaata
    14041 aagtcaatcc tttccatagc ctcaatggca gccagttgga aaaaggcaaa gcgttctccg
    14101 tcatcaaaat caccgtaaac atgaccacgg aagaaataat attgattgtc aataaagtag
    14161 aaggttacac catttaatac tgttttctta attccacaat actgtctgcg ccaaccaacg
    14221 ctcacctcaa aatgaagcac atcttcaatc tgatttccaa atttagcctc taccatatca
    14281 tagtagggta aaatcactgc aacttcgtgc ccagctttta ccagtgattt tggaagagcg
    14341 ccaatgacgt ctcccaaacc acctgttttt gaaaagggtg caccctctgc tgctacaaat
    14401 aaaattttca tgaatgaata tcctctgtta ctttagcacc tttcttaacc acaactggat
    14461 gttctgcagt tcctcgaatc acaacaccag gctcaacttc aacccctttg tccaagatag
    14521 catattcgac ctgagcccct tctccaataa caacacgagg gaagagcagg ctatctttaa
    14581 ccaagctatc cttatggaca tggatattac gtgatagaac agaattagct acttgacctt
    14641 caataatact accagaggca aactgagaag ttcttacctt agatgtatta gcatagtaag
    14701 ttggctcttc gtttttgacc tttgtataaa tcttttggtt tggtgagaaa agagaataga
    14761 atttttgtga ttcaagcata tcgatattcg cttgataata agatttaaca gagtgaatat
    14821 tggctagata gcccgtgtac tcgtaggcga aagctccctc ttttacagcc aaatcccgta
    14881 aaacatagcg caatttctct ggatgttctt ttttagcttc ttcttccaag tgttcaatca
    14941 accaaggtgt atcaacgaca aagatatctg tagacatatt gaacgtttca gctgttgact
    15001 tgctatcaaa gagtttatga gaaagaacat ggtctgtttc atctacatcc aagattgcat
    15061 ttacttctga aatatctttc ttagctagtt ttttataaac tacagtgata ggctcttttg
    15121 ttgtactatg taggtggaaa acttggttca aatcaatgtt aataagaaca tcgcagttga
    15181 gggcaaccgt ttggtttgag ccagaacgtt tcaaataagt aagaagctgt tggtagtatt
    15241 cttttccaac tgtactactt tctacacggg tattgtaaat tcctagatag taatggctaa
    15301 gaaaggttga taagccccac tcgcgtcctg aacgaatatg gtcaaatact gagctgatat
    15361 tatcctgctg gaaaatacca aagacactac gaacacctgc attagcaagg cttgaaagtg
    15421 ggaagtcaat caaacgatat ttcccaccaa atggcaaact tgctactgga cggtggtccg
    15481 tcaatgtcga catattgtga aaaccaactg tatttcctaa aatggcagaa tatttatcaa
    15541 tcttcatctg ttgctacccc cactacttca ttatatccta caacttgtac ttcatctgtt
    15601 ccatcaattt cgacaccgtc agaaataatc gcaccttcac caataatggc acgtttaatc
    15661 ttagctcctt gaccaatgat agctccactc atgataactg aatcaaggac ttccgctcct
    15721 tcgcgaactt gcgcgcctgt tgaaaggata gaatgtttaa cagttccatc aacgaaacat
    15781 ccgtctacaa ctaatgagtc ttccacatga gcatttgccc cgaggaagtt tggtggtgaa
    15841 atcaagtttc ttgagtaaat cttccattga cggttacgac tatccaaggc attttctgga
    15901 gaaatatact ccatgttcgc ttcccaaagt gactcaatag taccaacatc tttccaataa
    15961 ccactaaatt cgtaagcata aacactttca cctgactcaa ggtaatttgg aatgacattt
    16021 ttaccaaagt ctgacatgcc aaccttgctc ttttcagcag cgactaacat attacgaagg
    16081 cgttgccaat caaaaatgta gattcccata gaagcttttg tagatttagg ttgagctggt
    16141 ttttcttcaa attcaacaat acgattgtta gcatctgtgt tcatgatacc aaaacggctt
    16201 gcttctttaa gagggacgtc taaaactgct actgtcaagc tggcattatt atccttatga
    16261 gactggagca tatcatcata gtccattttg tagatgtgat ccccagacaa aatcaagaca
    16321 tactcaggat tgacactgtc gatatagtcg atattttggt aaatagcgtg actagtcccc
    16381 tcaaaccaac gatttccttc acttgcagaa taaggttgaa gaatagagac acctgaatta
    16441 ataccgtcta gtccccagct tgaaccattc ccaatatggt tgttgagagc aagtggttga
    16501 tactgtgtaa cgaccccaac attatgaatc cctgagttgg cacagtttga tagggcaaag
    16561 tcaatgatac ggtagcgccc accaaattgc acagctggtt ttgcgatgct ttgagtgagt
    16621 ttaccgagac gagttccttg cccaccagca agaatcaaag ctaacatttc atttttcatt
    16681 ttctactcct ttttggtttt tatttgtgac ggttttagta gatttcaagc gacgtttgat
    16741 tttccataca cttgctccca tagccggtag ggtaaaggtt aaggtctgct cataatcttt
    16801 ccatagtcct tcttgcgttt gaacagtttg attatgttct ttccaaacgc ctccccactc
    16861 ttccaactca gtattccata cttcttcgta aattcctgca acgggtagtc cgattgtaaa
    16921 atctttccgc tcaacaggta ccatgttaaa gatacagact aacatttctc cctttttacc
    16981 cttacgaata aaggaaagaa cactctggtc tcgattatcc gcatcaatga cttcaatacc
    17041 atcatagctg gtatcgattt cccacagaca gcgatgatct ttgtaaaact ggtttagctg
    17101 agaagtgaaa tacttcatct tagcattcat tgggtcttct aggttagacc attccaactg
    17161 ttcttcagat ttccattcta ggaattgacc gtattcgcta cccatgaaga gcaatttctt
    17221 accagggtga caaatttggt acgtatagag attgcgcaag cctgcgaatt gattgtaacg
    17281 atctccccac atcttatgca tcatactctt cttgccatga accacttcat cgtgcgagaa
    17341 tggcaagaga taattctcct tgaaaacata cataaagctg aaagtcacca ggttaaagtc
    17401 atatttacga taaatcggat cttcttcgta gaaacggagg atatcattca tccagcccat
    17461 gttccatttg tagtcaaatc ctagaccacc aatctctttc attcccgtaa tcttggttgc
    17521 agacgaactt tcttctgcaa tcatcatcac atctggatat tctaacttaa taacttcatt
    17581 caagcgttga aggaaataat aaccttcata gttgagattt ccgccatctt tattaggtgt
    17641 ccatggagca tcatcatagt ccaaatagag catgttgcta acagcatcca cacgaatacc
    17701 atccaaatga tagatatcaa tccaatgctt aatgcaagaa attaagaagg actggacttc
    17761 attttttcca aggtcaaaat taagggcacc ccaaccatgg ttatgagcct tattatggtc
    17821 ttggtattca aaagtcggtg tcccatcata ataggctaag gcatcatcat tgatggtaaa
    17881 gtgacctggt acccagtcca caataacccc aatattatgg gtatgacact cctcgacaaa
    17941 atcttgaaac tcctctggtc taccataggc atgctctaaa gcgaagtaac ccataagctg
    18001 gtacccccaa ctcaaaccta gtgggtggga catcaagggc ataaactcaa tatgagtata
    18061 gttcatctca actaggtaag gaatgagttc atctttcaat tgggcaaaac tataaggact
    18121 gccatcagga tttctcttcc aagagccagc atgaacctcg taaatattga caggacgttc
    18181 agcaaagccc caacgttttc ttcgtgccag ccaaagtcca tccctccatt tcttatcagg
    18241 aagctctgtt acgattgccc ctgttcctgg acgagcctca tacctgacag caaaagggtc
    18301 aatcttcatc agttgatgac cattttgacg tgtgacatga tatttgtaaa tatgcccttc
    18361 ttgagccata ttggtaaaga cttcccagac cccaaagtca tttcttacca ttggaatctg
    18421 attttcaatc caattggtaa aatcaccaac caagtgaaca gcctgagcat taggtgccca
    18481 aacacggaag gtatagccat actctccatt tagttcttcc ctatgtgctc ctagataatg
    18541 ttggagataa aaattttcac ccgtcataaa ggtttttaat gcttctctat tatccatata
    18601 ctccctttct cctgtaagcg ttttctatgt ttttattata ctaccttttt agagaagatt
    18661 caagtaaatt actatacttc tttaattatt ttgaaaatct acaacaagtt cacttactcg
    18721 ttcaattgta aatcaatatt ttttcaaaaa attgcgaaaa cacctttctt tttctactat
    18781 agtgaaatga aataaaacat gcgcaaatcg attaaggaat ttaatctaat ttctaacaat
    18841 gtcttagaaa tcaaagtgta ctattttaac ttcaatgtac tatatatagt aaaatgaaat
    18901 aataacagga caaatcgatc aggacagtca aatcgatttc taacaatgtt ttagaagtaa
    18961 atctgtacta ttctagtttc aatatactat aataccaaaa agttcgtatt ttttctataa
    19021 ttattattat tttatagcaa aaaataaaac caggaaaaca atttcctgat tttacacgtt
    19081 atttcacatc aaaaacaatg gatttgacat ttgtcatcgc ttcaatgcta tatttaattc
    19141 cttgcactcc agctccagaa cctttgacac caaggaatgg gaaattatct ggaccacgct
    19201 gggttttatt attaatgtgg actgtaccta cttcaagttt ttcagcaatt tcaaaggctt
    19261 ttttgaaatc atttgtaaag actgatgatt gaaggccgaa ttcagattcg ttggcaaagg
    19321 caatagcttc ctctacacta gccacacgaa tgattggtaa aacaggacca aatggctctt
    19381 cccatgccac tttcatatct tttgtaactt ggtcaaaaag cactggccag aggagattgc
    19441 cctcacgttt gattggtgta agagcctgag cctctttttc ttgtgcatcc tcaatcaagc
    19501 cccaaatgaa gtcggctgaa gcattgtcaa taacaggtgt aatatcagca ttgtcaaatg
    19561 gatcaccaac tgttaattta gaaacttctt cctgaagcaa agtagctaat ttatctgcta
    19621 cactttcgag aacaatgaca cgtttaatgg ccgtgcaacg ttgtcctgag tagctaaagg
    19681 ctcccgcaac aatttgcttg gcagcatgtt ccaaatctgc atcttctagt acaagagctg
    19741 catctttccc accaagttcc aacatgatag gacgcatacc agctaaacga ccaatacgtt
    19801 ctccaatagg agttgaacct gtaaagttga tgaagttgac ttctttgtgc tcaatgatat
    19861 aatccccaat ttctgaacca cgacctgtaa tggtgttgaa aacacctgcc ggaatccctg
    19921 cttcttcaaa tgctttagcc aacaagagtc cagaaatgga accttgtgtt ggtggcttca
    19981 acatgaccac attccctgca atcaaggcag gtgcaatttt agaagcagat aaattaactg
    20041 gataattaaa gggagcaatc gctagcacga taccaactgg ttcacgacgg acaacagcca
    20101 gtttgttttt acttgctgcc tcaaaaccac caccttccat tgcttgtcca gtgatacgga
    20161 gaccttcctc agcagcataa cgaatcaagt ctgctgtacg cactacttct ccaattgctg
    20221 ctttaatccc ttttgctact tctttggcaa ggatagtacc aattttttcc ttatcgcgtt
    20281 ctaaaatagc tgctgtttta tgcaaataag ccgcacgttc aattgctgat aaagctcgcc
    20341 atgctggcag ggctgcacgc gcagcttgca tagcctcatc agcttcagtc tgagtcatgg
    20401 ctggaactgt acccaattct tcttgattga ttggtgaata aatcgtaatt tcttgttcag
    20461 atgatttcca ttttccattt actaaattct gatatcttgt caaattcttg tcctcctgaa
    20521 aatgattaag atatatttta ccaaattttc agaaaataac aacccttttt gcaaaatttt
    20581 tgagattatt ttcacaagct tgatttttca aagtatactc aataaaaata aaaaaatcca
    20641 ctacgtcaag gcgaggctaa tgtggtttga agaaattttc gaagagcgtg aatgagtatc
    20701 atctatagta aaataaaaaa actgaacaat ttggttgggg acagccaaac caatttctca
    20761 caatgtttca gaaacaaggg tgtgctattc caatttcagc ctactataac tgtcatagat
    20821 tgctgaaaca aagtctaggt aaaagtcttc ataataaaaa gacctcctat caaatgttca
    20881 aaaactttga taggaggtct tgtttcgtga aaatatttat caaattttct atacaagtga
    20941 gctgttagcc aggttctttc tattctttca atttcaatga atggattttt taccaatact
    21001 cataactggg aatttttctg tctaaaaata gcgagataga tggtatttat aaaacactca
    21061 agacagctag actaatatca tttaaaacat tatcttcttt tgagcgactg ttggttacca
    21121 acatagctaa atttcctgca ttttcaaatt gatagggttc tgatttagca ttcacaacta
    21181 ccaagaggtg ttctttgccg tgaacttcat agataaggca gccgctatgt tcaatcgcag
    21241 aatgcacaaa gacatgatgg taaatttcat catagctaga gtaagaaaag gcaccagttt
    21301 ttgtcttcaa tcggatgact tgacggataa actcaatact gtcttgacgc tcattaatca
    21361 agttccagtt cacttggttc acactgtcag gagcattata gctattcatc gcacgctctc
    21421 tatcatcatg ggtcaactca ccattttcac cagtcgcaac cagtttggta cgaccaaatt
    21481 cttgaccgat ttccataaag gccatcccct gcatgagcag attcatggct gtggcagttt
    21541 cgaccttgcg catgatttgc tctgaacttt ggtctggatg aagggttgcc aataaatcgt
    21601 gaagattgta attgtcatgg gcttctacat agttaagcac ctgatttgga tgtgtatagc
    21661 ttcctaattc acgacttcct aggattgctt tagctagaat tggctctgtc gcagcaccac
    21721 tgacaaaacc tgacttgata gcaccataaa cttctccccc tttgacagca tcgcgctgat
    21781 tgtcattaaa gaaaccaata tttggcatct ggtaggcatt gtccttcttg gccttatcat
    21841 aaggggcaag acctgttccc atatcccatc cttctccata gaggataatg ttggagtcaa
    21901 tttcatccaa gctttgacga atcatctgca tggtcttgac atcatgaatc cccatcaagt
    21961 caaaacggaa gccgtcaata ttatattcct gcacccagta tagaagagaa tcaatcatat
    22021 acttgcgaaa catttcgtgt tcactggctg tttcatttcc aacacccgtt ccattctgga
    22081 aggtaccatc tggattcata cgataatagt aatcagggac tgttgtttgg aatggtgcat
    22141 caacaactga gaaggtatgg ttatagacta catccataat gactccaata cccgcatcgt
    22201 gataagcttg aaccatcacc ttcaaatcac gaatgacctg agctggatca tctggattag
    22261 ttgaaaaact agtttctggc gcgttatagt tttgtggatc ataaccccag ttgtaggtta
    22321 catttccatc ctcatcgtat tctttatgac ggtctgcaat tggttgcaat tgaacataat
    22381 tgtagcccag cttcttgatg taatcaaaag cagttgactg gccgtattgg ttaactgttc
    22441 cagcctgagc agcacccaag aaagttcctc gaagatgttc atctacaccc gatgtaggtg
    22501 atttagtcaa atcacgaata tgcatttcac agataactgc cttacatgga ttttccaagc
    22561 gccaagtagc ctccgaaccg tgcttaacct cgaagttttc aacttgcttt tctacatggc
    22621 tcagaatagc tgaacgtttg ccatcagggc tggtcgcgat tgtataagga tcacgtgtca
    22681 gtgtttggtg atgagggaat tggacttgat actgataagt cttacctacc aaatcttctt
    22741 caacatccaa actccagaca ccgattgtat tgtccttatg attataagag tagctattgc
    22801 ctcttttcat ctcaaaagtc ttccaaacgg gtgcatcatt agcagctgat tcataaacga
    22861 caacttgcac ttctgtcgct gtaggtgacc agagggaaaa atgagcctga ttgtcctcta
    22921 cacggcaacc caattctcct tggtaacccc aatgatgatc aaaactagca ctgttaatgg
    22981 ccttatcaaa ggcaaaagga ttttgatttt tatagaaagg actggcaata gcaggatttt
    23041 cagagtaata aatcctatca tcgccttcca aaatccagac ctctgttaat aggggatagt
    23101 gattaaaacg gatagaatat tctttactag tttgacctgt atgaaccaca aaattcaagc
    23161 tttctataac atgtgaactt gggtgttcaa agctaaataa agctccaaaa taatcttctt
    23221 tgtaggttag caaatcaatt cgttgatcct gactttttac aaaggagcaa gtgtcatatt
    23281 ctccattctt acgatggtaa tgaatgcgca tagggtagtt atacattttt tatttttcct
    23341 ttttactttg tttctatttc actaataaat ttttgtcaat ctcgtctcaa ttaacagaca
    23401 tagtcatatt ctctaaactc tgtttttaaa cgatccatta caaactttct agccatgcct
    23461 catctctgac ctggatacca agttcttgtg ctttttgcag tttacttcca gcgtctgcac
    23521 ctaccacgac gaggtcggtc tttttagaaa cactacctgt cactttggca cccagacttt
    23581 cgagtttact tttagcttct gagcgcttga gtcgttccaa ttttcctgtc aataccacgg
    23641 tcaaacctga caaggccgca tccgctacta ccgtctgtcc tttatagtcc agattgaccc
    23701 cagtttcttt caattctctg agcagaattt cagagccttc tgtcgcaaaa taagtctgaa
    23761 gacttttggc aatcacgcca cctagacttt caatactagc cacttcctct gaatctgcct
    23821 gagacagatt ttcaattgaa tggaaatatt gaagtaaaag ctgactagcc ttgcttccga
    23881 catgacgaat tcccaaacca aataagagct tctcggcaga attttccttt gatgcttgga
    23941 tagcctgata cagtttagca gcggactttt ccttaacccc ctctaaaagg aggaaatcct
    24001 cttcttgcaa acgataaata tccgccacat ccttgactaa attagcagca aaaagcttct
    24061 caacaataga tggaccaagg cctgtaatat tcatagcatc acgagaagca aagtgaatca
    24121 agccttccat gatttgagca gggcaacgcg gattgataca acgtagggcc acttcatctt
    24181 caaagtgcaa caagtcagag ttacaacttg gacagtttgt agggatatct agtttttctt
    24241 cagaaacccg tttggactct accacacgta aaacggcagg gatgatgtca ccagccttat
    24301 atacaatgac cgtatcgtct tttcggatat ctttttcagc aatataatct acattgtgca
    24361 gggtcgcacg gctaacagtc gtaccggcaa gttgtactgg tgttagatta gcagttggag
    24421 ttacaacacc ggtacggcca actgtccagt caactgataa gagttgagct tctttttctt
    24481 cagcagggaa cttgtaggct actgcccact ttggagcctt aacggtaaaa ccaagttctt
    24541 cttgacttgc taggtcgttg accttgatta ccactccatc aatatcgtaa ggcagatttt
    24601 cccgttcctg tcctacttct tggataaaat tccagatttc atctatgttt tcagccaaga
    24661 ttcgcttagg attgaccaca aaacctagtt gttctaggta cttcaaaccc ttttcttggc
    24721 tatcacgagt tgaagggctg gcttcttgat agagaaacgt tgcaagatta cgcttggcaa
    24781 ctactgctgt atccaactga cgcagagttc ctgctgccgc attacgagga ttagcaaatt
    24841 caggctctcc attttcttgg cgcacttggt taacttggtc aaaggaagcg cgtggcatgt
    24901 aacattcccc acgaactgtg atatctagtt cttctggcaa agtcaaaggg atgtccttaa
    24961 cacgcttgag gttttctgtg atattttcac caattgaacc atctccacgt gttaccccag
    25021 caaccaaaat ccccttttca taagtcagcg agatagataa gccatcgatt ttcagctcac
    25081 aaatataggt cggatgagcc acttccttac gaacacgcgc atcaaaagca tctagctcct
    25141 cacgtgaaaa agcatcctgc aaactataaa gaggatactg atgactgtat ttttcaaaac
    25201 catctaaaac cttgccacca acacgatgag tcggactgtc tgctagcact tgctctggat
    25261 aagcagtttc taactcgacc aactcacggt aaaggcggtc atactcactg tctgaaaccg
    25321 agggattatc gctggtatag tactcagtcg catagcgatt gagcaaagcg actaactcat
    25381 tcattctttt attcataaga ccattttacc ataaaacaag ccctcctcac aaacgagaag
    25441 ggcggaaaaa acacttagtt tgaaattatt tttgaaactc aagcaacctt atatcaattt
    25501 ttcaaaatga gttcgaacat aaataaacga tatacaagac aagatgataa caccacttcc
    25561 aattatcagg aaagaagaga gatgtacact tggcaagact gtcataaatc cttttgcaat
    25621 aggcataaat agaatagcta aggtaaaaat tgtactcagt actcttccaa gaaattcgct
    25681 ctcaaccttg gtttgtactt gagtaaaaaa gt
//
LOCUS       DAVBEO010000030        24905 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 009
            SAMEA1678075-rid20185393.denovo.030, whole genome shotgun sequence.
ACCESSION   DAVBEO010000030 DAVBEO010000000
VERSION     DAVBEO010000030.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678075
            Sequence Read Archive: ERR226392
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 24905)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24905)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980207.1
            Genome Coverage       :: 150x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:50:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 72 of 147
            Pseudo Genes (incomplete)         :: 72 of 147
            Pseudo Genes (internal stop)      :: 42 of 147
            Pseudo Genes (multiple problems)  :: 32 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24905
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678075-rid20185393.denovo.030"
                     /strain="KS 009"
                     /db_xref="taxon:1313"
     gene            129..1304
                     /gene="mutY"
                     /locus_tag="VQ543_001250"
     CDS             129..1304
                     /gene="mutY"
                     /locus_tag="VQ543_001250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="A/G-specific adenine glycosylase"
                     /protein_id="HET2611971.1"
                     /translation="MLDLKEYGIVMWPEEKVISFREKLLAWYDENKRDLPWRRSKNPY
                     HIWVSEIMLQQTRVDTVIPYYERFLDWFPTVESLATAPEESLLKAWEGLGYYSRVRNM
                     QAAAQQIMTDFGGQFPNTYEGISSLKGIGPYTAGAISSIAFNLPEPAVDGNVMRVLAR
                     LFEVNHDIGIPSNRKIFQAMMEILINPDRPGDFNQALMDLGSDIESPVNPRPEESPVK
                     DFSAAYQNGTMDRYPIKSPKKKPVPIYLKALVVKNSQGQFLLEKNESEKLLAGFWHFP
                     LIEVDNFSQEEQFDLFHQVAEESVNFGPSPEESFQQDYDLDVDWLDVCFDTVQHVFSH
                     RKWHVQIVAGQVSDFHDFSDREVRWLSPEEFKNYPLAKPQQKIWQAYAQANLDSSQD"
     gene            1359..2063
                     /locus_tag="VQ543_001251"
     CDS             1359..2063
                     /locus_tag="VQ543_001251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000722069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET2611972.1"
                     /translation="MKKILIVDDEKPISDIIKFNMTKEGYEVVTAFNGREALEQFEAE
                     QPDIIILDLMLPEIDGLEVAKTIRKTSSVPILMLSAKDSEFDKVIGLELGADDYVTKP
                     FSNRELQARVKALLRRSQPMPVDGQEADSKPQPIQIGDLEIVPDAYVAKKYGEELDLT
                     HREFELLYHLASHTGQVITREHLLETVWGYDYFGDVRTVDVTVRRLREKIEDTPSRPE
                     YILTRRGVGYYMRNNA"
     gene            2056..3405
                     /gene="vicK"
                     /locus_tag="VQ543_001252"
     CDS             2056..3405
                     /gene="vicK"
                     /locus_tag="VQ543_001252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall metabolism sensor histidine kinase
                     VicK"
                     /protein_id="HET2611973.1"
                     /translation="MLDLLKQTIFTRDFIFILILLGFILVVTLLLLENRRDNIQLKQI
                     NQKVKDLIAGDYSKVLDMQGGSEITNITNNLNDLSEVIRLTQENLEQESKRLNSILFY
                     MTDGVLATNRRGQIIMINDTAKKQLGLVKEDVLNRSILELLKIEENYELRDLITQSPE
                     LLLDSQDINGEYLNLRVRFALIRRESGFISGLVAVLHDTTEQEKEERERRLFVSNVSH
                     ELRTPLTSVKSYLEALDEGALCETVAPDFIKVSLDETNRMMRMVTDLLHLSRIDNATS
                     HLDVELINFTAFITFILNRFDKMKGQEKEKKYELVRDYPINSIWMEIDTDKMTQVVDN
                     ILNNAIKYSPDGGKITVRMKTTEDQMILSISDHGLGIPKQDLPRIFDRFYRVDRARSR
                     AQGGTGLGLSIAKEIIKQHKGFIWAKSEYGKGSTFTIVLPYDKDAVKEEVWEDEVED"
     gene            3407..4216
                     /locus_tag="VQ543_001253"
     CDS             3407..4216
                     /locus_tag="VQ543_001253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HET2611974.1"
                     /translation="MSEIGFKYSILASGSSGNSFYLETSKKKLLVDAGLSGKKITSLL
                     AEINRKPEDLDAILITHEHSDHIHGVGVLARKYGMDLYANEKTWQAMENSKYLGKVDS
                     SQKHIFEMGKTKTFGDIDIESFGVSHDAVAPQFYRFMKDDKSFVLLTDTGYVSDRMAG
                     IVENADGYLIEANHDVEILRSGSYAWRLKQRILSDLGHLSNEDGAEAMIRTLGNRTKK
                     IYLGHLSKENNIKELAHMTMVNQLAQADLGVGVDFKVYDTSPDTATPLTEI"
     gene            4307..4549
                     /locus_tag="VQ543_001254"
     CDS             4307..4549
                     /locus_tag="VQ543_001254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001853822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="HET2611975.1"
                     /translation="MTTITLKVSEADKTFMKAMAKFEGVSLSELIRTKTLEALEDEYD
                     ARVADLAYQEYLEDLEKGVEPITWEEMMHDLGLKDE"
     gene            4551..4805
                     /locus_tag="VQ543_001255"
     CDS             4551..4805
                     /locus_tag="VQ543_001255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HET2611976.1"
                     /translation="MYKLVPTRRFIKQLKKLDRYTQKLITNYLQTNVLEDPRRHGKAL
                     VGNRVGQWRYRIGNYRVIVQIVDDELVVATLEVGHRRDIY"
     gene            4852..5625
                     /locus_tag="VQ543_001256"
     CDS             4852..5625
                     /locus_tag="VQ543_001256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000731134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ion transporter"
                     /protein_id="HET2611977.1"
                     /translation="MKKKWFFADYYDTTIILLALISVILVLLGFAEMIDLDNPPYSII
                     DLVIWGVFVIDYSWRFFTTKRKWRFILENIFDLLAILPLNAIFTVFRLGRIFRLAKLT
                     KLLKLTRLLRIIGLTGKLERKISRFLRTNGLIYILYVNIFIVLVGSSILSVVEEKSFS
                     DSLWWALVTVTTVGYGDIVPASIFGKWLAVLLMLVGIGTIGMLTSALTNFFVKDNPDE
                     QIKLDKLKDELSSQRILLEKQSKKIEELHKMIQDLIEKT"
     gene            complement(5885..6871)
                     /locus_tag="VQ543_001257"
     CDS             complement(5885..6871)
                     /locus_tag="VQ543_001257"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019768616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HET2611978.1"
                     /translation="MTSTKQHKKVILVGDGAVGSSYAFALVNQGIAQELGIIEIPQLH
                     EKAVGDALDLSHALAFTSPKKIYAAQYSDCADADLVVITAGAPQKPGETRLDLVGKNL
                     AINKSIVTQVVESGFKGIFLVAANPVDVLTYSTWKFSGFPKERVIGSGTSLDSARFRQ
                     ALAEKLDVDARSVHAYIMGEHGDSEFAVWSHANIAGVNLEEFLKDTQNVQEAELIELF
                     EGVRDAAYTIINKKGATYYGIAVALARITKAILDDENAVLPLSVFQEGLYGVENVFIG
                     QPAVVGAHGIVRPVNIPLNDAETQKMQASAKELQAIIDEAWKNPEFQEASKN"
     gene            7065..9533
                     /gene="gyrA"
                     /locus_tag="VQ543_001258"
     CDS             7065..9533
                     /gene="gyrA"
                     /locus_tag="VQ543_001258"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003244540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase subunit A"
                     /protein_id="HET2611979.1"
                     /translation="MQDKNLVNVNLTKEMKASFIDYAMSVIVARALPDVRDGLKPVHR
                     RILYGMNELGVTPDKPHKKSARITGDVMGKYHPHGDSSIYEAMVRMAQWWSYRYMLVD
                     GHGNFGSMDGDSAAAQRYTEARMSKIALEMLRDINKNTVDFVDNYDANEREPLVLPAR
                     FPNLLVNGATGIAVGMATNIPPHNLGETIDAVKLVMDNPEVTTKDLMEVLPGPDFPTG
                     ALVMGKSGIHKAYETGKGSIALRSRTEIETTKTGRERIVVTEFPYMVNKTKVHEHIVR
                     LVQEKRIEGITAVRDESNREGVRFVIEVKRDASANVILNNLFKMTQMQTNFGFNMLAI
                     QNGIPKILSLRQILDAYIEHQKEVVVRRTRFDKEKAEARAHILEGLLIALDHIDEVIR
                     IIRASETDAEAQAELMSKFKLSERQSQAILDMRLRRLTGLERDKIQSEYDDLLALIAD
                     LADILAKPERVSQIIKDELDEVKRKFSDKRRTELMIGQVLSLEDEDLIEESDVLITLS
                     NRGYIKRLDQDEFTAQKRGGRGVQGTGVKDDDFVRELVSTSTHDHLLFFTNKGRVYRL
                     KGYEIPEYGRTAKGLPVVNLLKLDEDESIQTVINVESDRSDDAYLFFTTRHGIVKRTS
                     VKEFANIRQNGLKALNLKDEDELINVLLAEGDMDIIIGTKFGYAVRFNQSAVRGMSRI
                     ATGVKGVNLREGDTVVGASLITDQDEVLIITEKGYGKRTVATEYPTKGRGGKGMQTAK
                     ITEKNGLLAGLMTVQGDEDLMIITDTGVMIRTNLANISQTGRATMGVKVMRLDQDAQI
                     VTFTTVAVAEKEEVGTENETEGEE"
     gene            9533..10276
                     /gene="srtA"
                     /locus_tag="VQ543_001259"
     CDS             9533..10276
                     /gene="srtA"
                     /locus_tag="VQ543_001259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sortase SrtA"
                     /protein_id="HET2611980.1"
                     /translation="MSQKNNKKKNKRKNLLTNILAGFLILLSLALIFNTQIRNIFIVW
                     NTNKYQVSQVSKEKLEENQDTEGNFDFDSVKAISSEAVLTSQWDAQKLPVIGGIAIPE
                     LEMNLPIFKGLDNVNLFYGAGTMKREQVMGEGNYSLASHHIFGVDNANKMLFSPLDNA
                     KNGMKIYLTDKNKVYTYEIREVKRVTPDRVDEVDDRDGVNEITLVTCEDLAATERIIV
                     KGDLKETKDYSQTSDEILTAFNQPYKQFY"
     gene            10520..11317
                     /locus_tag="VQ543_001260"
     CDS             10520..11317
                     /locus_tag="VQ543_001260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000254803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HET2611981.1"
                     /translation="MVSSEFISKIEFACNKKESLYSQSKFKYAIRSMFAGAFLTFSTA
                     AGAVGADLINKIAPGSGRFLFPFVFAWGLAYIVFLNAELVTSNMMFLTAGSFLKKISW
                     RKTAEILLYCTLFNLIGALIAGWGFAHSAAYANLTHDSFISGVVEMKLGRSNELVLLE
                     AILANIFVNIAILSFILVKDGGAKLWLVLSAIYMFVFLTNEHIAANFASFAIVKFSVA
                     ADSIANFGVGNMLRHWGVTFIGNFIGGGLLMGLPYAFLNKNEDTYVD"
     gene            11465..11587
                     /locus_tag="VQ543_001261"
     CDS             11465..11587
                     /locus_tag="VQ543_001261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent transferase"
                     /protein_id="HET2611982.1"
                     /translation="MTCDFKFETLQLHAGQVVAPATKSRAVPIYQTTSFIFDDT"
     gene            11609..12649
                     /locus_tag="VQ543_001262"
     CDS             11609..12649
                     /locus_tag="VQ543_001262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001231001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-acetylhomoserine
                     aminocarboxypropyltransferase/cysteine synthase"
                     /protein_id="HET2611983.1"
                     /translation="MRKPGNIYTRITNPTTAALEGGVEALATASGMTAVTYTILALAH
                     AGDHVVAASTIYGGTFNLLKEPLPRYGITTTFVDVDNLEEVEAAIKDNTKLVLIETLG
                     NSLINIPDLEKLAEIAHKHQIPLVSDNTFAIPYLINVFSHGVDIAIHSATKFIGGHGT
                     TIGGIIVDSGRFDWTASGKFPQFVDEGPSCHNLSYTCDVGAAAFIIAVRVQLLRDTGA
                     ALSPFNAFLLLQRLETSSLRVERHVQNAETIVDFLVNHPKVEKVNYPKLADSPYHALA
                     EKYLPKDVGSIFTFHVKGGEEEARKVIDNLEIFSDLANAADAKSLVVHPATTTHGQLS
                     EKDLEAAGVTPN"
     gene            12820..14094
                     /locus_tag="VQ543_001263"
     CDS             12820..14094
                     /locus_tag="VQ543_001263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001002592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2130 domain-containing protein"
                     /protein_id="HET2611984.1"
                     /translation="MNEIKCPNCGEVFTVNESQYAELLSQVRTAEFDKELHDRMKQEL
                     ALAEQKAMNEQQTKLAQKDQEIAQLQSQIQNFDTEKELAKKEVEQTSHEALLAKDKEV
                     QLLENQLATLRLEHENQLQKTLSDLEKERDQVKNQLLLQEKENELSLASVKQNYEAQL
                     KAASEQVEFYKDFKAQQSTKAIGESLEQYAESEFNKVRSFAFPNAYFEKDNKVSSRGS
                     KGDFIFRECDENGVEIISIMFEMKNEADGTEKKHKNADFYKELDKDRREKNCEYAVLV
                     TMLEADNDYFNTGIVDVSHEYEKMYVVRPQFFIQLIGLLRNAALNSLKYKQELALVRE
                     QNIDITHFEEDLDAFKLAFAKNYNSASTNFGKAIDEIDKAIKRMEEVKKFLTTSENQL
                     RLANNKLEDVSVKKLTRKNPTMKAKFEALKGE"
     gene            14104..14982
                     /gene="truB"
                     /locus_tag="VQ543_001264"
     CDS             14104..14982
                     /gene="truB"
                     /locus_tag="VQ543_001264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007516878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(55) synthase TruB"
                     /protein_id="HET2611985.1"
                     /translation="MNGIINLKKEAGMTSHDAVFKLRKILGTKKIGHGGTLDPDVVGV
                     LPIAVGKATRMVEFMQDEGKIYEGEIILGYSTTTEDASGEVVAETPVLSPLDEKLVDE
                     AIASLTGPITQIPPMYSAVKVNGRKLYEYARAGQEVERPERQVTIYQFERTSPISYDG
                     QLARFTFRVKCSKGTYIRTLSVDLGEKLGYAAHMSHLTRTSAAGLQLEDALTLEEIAE
                     KVEAGQLDFLHPLEIGTGDLVKVFLTPEEATEVRFGRFIELDQTDKELAAFEDDKLLA
                     ILEKRGNLYKPRKVFS"
     gene            15250..15525
                     /locus_tag="VQ543_001265"
     CDS             15250..15525
                     /locus_tag="VQ543_001265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HET2611986.1"
                     /translation="MEQLLQQKEINENSELSHLFRLAIQNLDRNEKYQSVMANLSQGL
                     SLYLMTHHYQAPKSVIDFGLWIAKAPSQERGRLAFLQMLAQTLQGFR"
     gene            15633..16271
                     /gene="udk"
                     /locus_tag="VQ543_001266"
     CDS             15633..16271
                     /gene="udk"
                     /locus_tag="VQ543_001266"
                     /EC_number="2.7.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uridine kinase"
                     /protein_id="HET2611987.1"
                     /translation="MQNRPIIIGVTGGSGGGKTSVSRAILSHFPDEKISMIEHDSYYK
                     DQSHLTFEERVKTNYDHPFAFDTDLMIEQIKELLAGRPVDIPTYDYTEHTRSSKTYRQ
                     EPQDVFIVEGILVLEDKRLRDLMDIKIFVDTDDDVRIIRRIKRDMEERGRSLDSVINQ
                     YLGVVKPMYHQFIESTKRYADIVIPEGVSNTVAIDLLTTKIAKILEEARNSK"
     gene            16399..17739
                     /locus_tag="VQ543_001267"
     CDS             16399..17739
                     /locus_tag="VQ543_001267"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000417449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="HET2611988.1"
                     /translation="MEKYLSVTTLTKYLKMKFDKDPYLERVYLTGQVSNFRKRPTHQY
                     FSLKDDHAVIQATIWSGIYQKLGFDLEEGMKINVIGRVQVYEPSGSYSIIIEKAEPDG
                     VGALAIQFEQLKKKLTEEGLFQERFKQALPQFSKRIGVVTSRSGAVIRDIITTVSRRF
                     PGVDILLYPTKVQGEGAAEEIARNIARANQRDDLDLLIIGRGGGSIEDLWAFNEEIVV
                     RAIFESRLPVISSVGHETDVTLADFVADRRAATPTAAAELATPVTKLDVLAHLQNQEK
                     RMATAVRNVLSKKQEALKKCSQSVIFRQPERLYDGYLQRLDQLQLRLKQSLRTRISDN
                     KQLVQARTHQLVQLSPVTKIQRYQDRLGQLDKLLGSQMALVYDAKVAEAKRLSEALLM
                     LDTSRIVARGYAIVKKEESVVDSVESLKKKDQVTLLMRDGQVELEVKDVKTKEI"
     gene            17717..17929
                     /locus_tag="VQ543_001268"
     CDS             17717..17929
                     /locus_tag="VQ543_001268"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="HET2611989.1"
                     /translation="MSKQKKFEENLAELETIVQSLENGEIALEDAITAFQKGMVLSKE
                     LQATLDKAEKTLVKVMQEDGTESDFE"
     gene            17926..18801
                     /locus_tag="VQ543_001269"
     CDS             17926..18801
                     /locus_tag="VQ543_001269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HET2611990.1"
                     /translation="MKKQEKLALVESALEDFYGDQQFASSLRESVLYSIHAGGKRIRP
                     FLLLEVLESLQVTIKPAHAQVATALEMIHTGSLIHDDLPAMDDDDYRRGRLTNHKKFG
                     EAMAILAGDALFLDPYALIAQADLPSQIKVDLIANLSLASGSLGMVAGQVLDMEGEHQ
                     HLSLEELQTIHANKTGKLLAYPFQAAAIIAELSPEMQVKLKTVGELIGLAFQVRDDVL
                     DVTASFEEIGKTPQKDLQAEKSTYPALLGLEESIAFCNQTLDQANEKLEEIAQQLPFE
                     TESIVSVVESLRING"
     gene            18794..19609
                     /locus_tag="VQ543_001270"
     CDS             18794..19609
                     /locus_tag="VQ543_001270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001041085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlyA family RNA methyltransferase"
                     /protein_id="HET2611991.1"
                     /translation="MAKERVDVLAYKQGLFETREQAKRGVMAGLVVAVLNGERFDKPG
                     EKIPDDTELKLKGEKLKYVSRGGLKLEKALQVFDLSVDGATTIDIGASTGGFTDVMLQ
                     NSAKLVFAVDVGTNQLAWKLRQDPRVVSMEQFNFRYAEKTDFEQEPSFASIDVSFISL
                     SLILPALHSVLADQGQVVALVKPQFEAGREQIGKNGIIRDAKIHQNVLESVTAMAVEA
                     GFSVLGLDFSPIQGGHGNIEFLAYLKKEKSASNQILAEIKEAVERAHSQFKNE"
     gene            19602..20033
                     /locus_tag="VQ543_001271"
     CDS             19602..20033
                     /locus_tag="VQ543_001271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001034407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HET2611992.1"
                     /translation="MNKKERLEKIRRLVTDYQIGTQEEIVEHLKEAGITATQATVSRD
                     IKELGIVKIPLRDNTYVYELPKSIVKSLQLAEDNIESAELMDKMINLQVIPGNTAFVK
                     AQLIETFADKIFSCLTDDSSILVIARSGSLAEEIFEQVKNW"
     gene            20040..21707
                     /gene="recN"
                     /locus_tag="VQ543_001272"
     CDS             20040..21707
                     /gene="recN"
                     /locus_tag="VQ543_001272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecN"
                     /protein_id="HET2611993.1"
                     /translation="MLLEISIKNFAIIEAISLNFEKGMTVLTGETGAGKSIIIDAMNM
                     MLGARATTDVIRHGAPKAEIEGLFSVENSRLLQEIFDEQGLELGDEIIIRREILQNGR
                     SISRVNGQMVNLSVLRTIGQHLVDIHGQHDHEELMRPQLHIQMLDEFGDAAFWDLKET
                     YQTSFDAYRKMRKQVLEVKKNQQEHKARIEMLEFQMAEIEAANLQAGEDLDLNQERDK
                     LLNHKNIADTLTNAYSMLDNEDFSSLANVRSAMNDMESVEEYDPEYREISSSLSETYY
                     VLEDISKRLEAIIEDLDFDGNRLMQVENRLDLLHTITRKYGGTVDDVLLYFAKITEEY
                     NLLTGNNLSSEDMEAELKKLEVNLVNLAGQLASARHNLAQQLEAEIKQELQDLYMEKA
                     QFQVRFSKGKFSREGNKMVEFYISTNPGEDFKPLVKVASGGELSRLMLAIKSAFSRKE
                     GKTSIVFDEVDTGVSGRVAQAIAQKIHKIGQHGQVLAISHLPQVIAIADYQFFIEKIS
                     NDHSTVSTVRLLTVEERVEEVAKMLAGDDVTEAALTQARELLRNREK"
     gene            21709..22437
                     /locus_tag="VQ543_001273"
     CDS             21709..22437
                     /locus_tag="VQ543_001273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000133310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine protein phosphatase"
                     /protein_id="HET2611994.1"
                     /translation="MTDYYVIGDVHGKAGMLEDLLKTWDGQPQLLFLGDLIDRGEDSH
                     RVLEMVKDLVDNQGAICLSGNHEYMFLTWLDDPEESYDHYSRNGGDTTINSILGRPLD
                     APVDGVEDAKRVAAEAADLVEFIRQMPFVVETDKYIFVHAGIDLTLDDWHETTDYKKV
                     WLRKPFHGAENHTGKTIVFGHTPVYGLLQQERGTSELWTTEDGKIGMDGGAVYGGVLH
                     GIVFTDQGMTEHHFIENDGFVAED"
     gene            22516..24339
                     /gene="lepA"
                     /locus_tag="VQ543_001274"
     CDS             22516..24339
                     /gene="lepA"
                     /locus_tag="VQ543_001274"
                     /EC_number="3.6.5.n1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001047203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor 4"
                     /protein_id="HET2611995.1"
                     /translation="MNLEELKKRQEKIRNFSIIAHIDHGKSTLADRILEKTETVSSRE
                     MQAQLLDSMELERERGITIKLNAIELNYTAKDGETYIFHLIDTPGHVDFTYEVSRSLA
                     ACEGAILVVDAAQGIEAQTLANVYLALDNDLEIMPIINKIDLPAADPERVRTEIEDVI
                     GLDASEAVLASAKAGIGIEEILEQIVEKVPAPTGDVTAPLKALIFDSVYDAYRGVILQ
                     VRVMDGVVKPGDKIQLMSNSKTFDVAEVGIFTPKAVGRDFLATGDVGYIAASIKTVQD
                     TRVGDTVTLATNPAAEPLHGYKQMNPMVFAGLYPIESNKYNDLREALEKLQLNDASLQ
                     FEPETSQALGFGFRCGFLGLLHMDVIQERLEREFNIDLIMTAPSVIYKVNLTDGESMD
                     VSNPSEFPDPTKIATIEEPYVKAQIMVPQEFVGAVMELAQRKRGDFVTMDYIDDNRVN
                     VIYQIPLAEIVFDFFDKLKSSTRGYASFDYELSEYRPSKLVKMDILLNGDKVDALSFI
                     VHKDFAYERGKLIVDKLKKIIPRQQFEVPIQAAIGHKIVARTDIKALRKNVLAKCYGG
                     DVSRKRKLLEKQKAGKKRMKSIGSVEVPQEAFLSVLSMDEE"
     gene            complement(24541..24621)
                     /locus_tag="VQ543_001275"
                     /pseudo
     CDS             complement(24541..24621)
                     /locus_tag="VQ543_001275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
BASE COUNT         7544 a         4400 c         5746 g         7215 t
ORIGIN      
        1 gctagcttcc tagtttgctc tttgattttc attgagtata agtagataga aaagttatat
       61 actatctatt gaaaatatta taaatcagat acaaagacag gtgaaacctt ctgtgttata
      121 ctagagatat gttagatttg aaagaatacg gtatcgtcat gtggccggag gagaaagtca
      181 tttctttccg tgagaaactt ctcgcttggt atgatgaaaa caaaagagat ttgccttgga
      241 ggagaagtaa aaatccttat cacatctggg tatctgaaat catgcttcag cagaccaggg
      301 tggatacagt tatcccttac tacgaaagat tcctggactg gtttccaact gtcgaaagtc
      361 tggcaactgc gcctgaggag agtttactga aagcttggga gggcttgggc tattattctc
      421 gagttcgcaa tatgcaggct gcagcccagc agattatgac tgactttggt ggccaatttc
      481 caaataccta tgaaggaatt tccagcttga aagggattgg accttacaca gcaggagcca
      541 tttccagtat tgcttttaac ttgcctgagc cagctgtaga tggtaatgtc atgcgggtct
      601 tggcgcgtct gtttgaagtc aaccacgata ttgggattcc aagtaatcga aaaatttttc
      661 aggcaatgat ggagatcttg attaatccgg atcgtccggg tgattttaat caagccttga
      721 tggacttagg gtctgatatt gagtctcctg taaatcccag acctgaagaa agcccagtca
      781 aggactttag tgcggcatat cagaatggaa ccatggaccg ttatccaatt aaatctccta
      841 agaaaaagcc ggttcctatt tatcttaaag cattagttgt gaaaaattct caaggacaat
      901 ttttacttga aaaaaatgaa agcgaaaagc tcttggcagg tttttggcat ttccccctta
      961 tagaagttga taacttttcg caagaagagc agtttgacct ctttcatcag gttgcggaag
     1021 aaagtgtgaa ctttggcccc agtccagaag agagtttcca gcaggactat gacctagatg
     1081 ttgattggct tgatgtttgt tttgatacag tccagcatgt ttttagtcat cgaaaatggc
     1141 atgtacagat tgtagcaggt caggtgagtg acttccatga tttttcagat agggaagttc
     1201 gttggctttc accagaagaa ttcaagaatt acccacttgc caaaccccaa caaaaaatct
     1261 ggcaggctta tgcacaagcc aacttagaca gtagccaaga ctagctattg tgtcttctga
     1321 ctattttttg gtataatagt agagaaaaag gtgaacatat gaaaaaaata ctaattgtag
     1381 atgatgagaa accaatctcg gatattatca agtttaatat gaccaaggaa ggttacgaag
     1441 ttgtaactgc ttttaatggt cgtgaagcgc tagagcaatt tgaagcagag caaccagata
     1501 ttattattct ggatttgatg cttccagaaa ttgatggttt agaagttgct aagaccattc
     1561 gtaagacaag cagtgtgccc attcttatgc tttcagccaa agatagtgaa tttgataagg
     1621 ttatcggttt ggaacttggg gcagatgact atgtaacgaa acccttctcc aatcgtgagt
     1681 tgcaggcgcg tgttaaagct cttctgcgtc gttctcaacc tatgccagta gatggtcagg
     1741 aagcagatag taaacctcaa cctatccaaa ttggggattt agaaattgtt ccagacgcct
     1801 acgtggctaa aaaatatggc gaagaactag acttaaccca tcgtgaattt gagcttttgt
     1861 atcatttagc atcgcataca ggtcaagtca tcacgcgcga acacttgctt gagactgtct
     1921 ggggttatga ctattttggt gatgtccgta cagttgatgt gactgtacga cgtctgcgtg
     1981 agaagattga agatacgccc agccgaccag agtatatctt gacgcgccgt ggtgtagggt
     2041 attacatgag aaataatgct tgatttactg aaacaaacca tttttaccag agattttatc
     2101 tttatcctga ttttgttagg tttcatcctt gttgtgaccc tcttattact ggaaaataga
     2161 cgtgataata ttcagttgaa gcaaatcaat caaaaggtta aagatttgat tgcaggagat
     2221 tattccaagg ttcttgatat gcaaggtggg tctgaaatca ccaatattac caataatttg
     2281 aatgacttgt cggaggttat tcgtctcact caggaaaatc tagaacaaga gagtaagagg
     2341 ctaaatagta ttctgtttta tatgacagat ggggttcttg cgaccaaccg tcggggtcag
     2401 attatcatga ttaacgatac agccaagaag caactggggt tggttaagga agatgttctg
     2461 aatagaagca ttttggaatt gctcaagata gaagaaaact atgaattgcg tgatttgatt
     2521 acccaaagtc cagaattgtt gctagattcc caagatatca atggcgaata tttgaacctt
     2581 cgagttcgct ttgccttgat acgtcgagag tctggcttta tttcaggttt ggtggctgtt
     2641 ttgcatgata cgacggagca ggagaaggaa gaacgcgaac gaagactctt tgtttccaat
     2701 gttagccatg agttacggac tcctctgact agcgtaaaat cctatcttga agccttggat
     2761 gagggggctt tgtgtgaaac tgtagcacca gactttatca aggtttctct tgatgagacc
     2821 aaccgtatga tgcgcatggt gacggatctc ctccatcttt cacgtattga taatgctacc
     2881 agtcacctag atgtggaact gattaacttc actgctttta ttacctttat cctcaatcgt
     2941 tttgacaaga tgaaaggaca ggaaaaggag aaaaaatatg agttggtgag agattatccc
     3001 atcaattcta tctggatgga aattgataca gataagatga cgcaggttgt cgacaatatt
     3061 ttaaataatg ctattaagta ttcgccagat gggggtaaaa tcactgtcag aatgaagaca
     3121 actgaagacc agatgatttt atccatttct gaccacggtt tggggattcc taagcaggat
     3181 ttaccacgta tctttgaccg tttctatcgt gtggatcgtg ctagaagtcg tgcacaaggt
     3241 ggtacaggtc taggactgtc tatcgctaaa gaaattatca aacaacataa gggctttatt
     3301 tgggccaaga gtgaatacgg caagggttca acctttacca ttgtgctccc ttatgataag
     3361 gatgcagtga aagaagaagt atgggaggat gaagtagaag actagaatga gtgaaatagg
     3421 ctttaaatac agtattttag cgtcgggttc cagtggaaat tctttttatc tggaaacctc
     3481 aaaaaagaag cttttagtag atgcaggctt gtctggcaag aaaattacca gtctgctagc
     3541 tgaaattaac cgtaagccag aagacctgga tgccatcttg attacccatg agcattcaga
     3601 tcatatccat ggagtaggcg ttttggctcg caagtatggt atggatcttt atgccaatga
     3661 aaagacctgg caagctatgg aaaatagtaa atatcttggc aaggtggatt cttcgcaaaa
     3721 gcatattttt gaaatgggta aaaccaaaac ctttggagat atcgacatcg agagttttgg
     3781 tgtaagccat gatgcagtcg caccgcagtt ctatcgcttt atgaaggatg ataagagttt
     3841 tgtcctcttg acagatacag gttatgtcag tgaccgtatg gcgggcattg tcgaaaatgc
     3901 ggatggttat cttatcgagg ccaaccatga tgtagagatt ttgcgatcag gttcttacgc
     3961 ttggcgcctc aaacaacgaa tcctatctga ccttggtcac ctttctaacg aggacggtgc
     4021 tgaagctatg attcggacgc taggaaatcg tactaagaag atttaccttg ggcatttatc
     4081 taaggaaaac aatatcaagg aactggctca tatgaccatg gtcaatcagc tggctcaagc
     4141 tgatctggga gtcggagtag actttaaggt ttatgatacc tcaccagata ccgcaacacc
     4201 attgacagag atatagaaag aacgctgaga aggtgttctt tttatattga ctggacacct
     4261 aaaaagtaat acaatggtgt taccattaaa aaagggagca caaaagatga ctactattac
     4321 attaaaagtt tctgaagctg ataaaacatt tatgaaagca atggctaagt ttgaaggagt
     4381 ttccctttcg gaacttattc gcaccaaaac tcttgaagcc ctagaagatg aatacgatgc
     4441 tcgtgtggca gatttagcct atcaagagta tttagaagac ttggaaaaag gagttgaacc
     4501 cattacttgg gaagaaatga tgcatgattt aggcttgaag gatgaataat ttgtataaat
     4561 tagttccaac aagacgtttt atcaagcaat tgaaaaaatt ggaccgttat acgcagaagc
     4621 taattacaaa ctatttacaa accaatgttt tggaagatcc aagacgacac ggaaaggctt
     4681 tggttggtaa tcgcgttggt caatggcgct atagaattgg taattatcga gttatcgtac
     4741 aaattgtaga tgatgaatta gttgttgcta ctctagaagt tggtcatcgg agagatattt
     4801 attaaattaa agctgagtaa taacagtata gaaagtaagg agagtaaaaa tttgaagaaa
     4861 aaatggtttt ttgcagatta ttatgacaca acaattattt tacttgcttt aatctctgtt
     4921 attctggtat tacttggatt tgctgagatg attgatttgg acaatccgcc ttatagtatt
     4981 attgatttag taatctgggg tgtttttgta attgattata gttggcgctt ttttacgact
     5041 aaaagaaaat ggcgctttat tcttgaaaat atttttgatt tattggctat tctcccttta
     5101 aatgctattt ttacagtgtt tcgattaggg cgtatctttc gtttagctaa actaacaaaa
     5161 ttactgaaac tgactcgttt acttagaata attggactta caggtaaatt agaaagaaaa
     5221 attagtagat tcttacggac aaatggcctg atttatatct tgtatgttaa tatctttatt
     5281 gttctagtag ggagttcgat tttatccgtt gttgaagaaa aatccttctc agatagtctt
     5341 tggtgggctc ttgtgacagt aactactgtt ggatatgggg atattgttcc tgcttccatt
     5401 tttgggaaat ggctagcagt tttactgatg cttgtcggta ttggaacaat agggatgtta
     5461 acaagtgctt tgacgaactt ttttgtaaag gataatccag atgaacagat aaaacttgat
     5521 aaactcaaag atgaattatc gagccaaaga atattactag agaaacaatc taaaaagata
     5581 gaagaactac ataaaatgat acaagatttg attgaaaaaa cataataaaa ataaagatga
     5641 gacaaagttt gagctgagga gaaatcaagt aagttttgac acaatagaac gcatattatc
     5701 aggtataaaa acttgatact atgcgtttta tagagaaata aaataaaatc tgaacaaatc
     5761 aattaggaat ttaaagcatt ttataacaac gttttagagt gatggggtgc tatttcaact
     5821 tcaacctact ataatacaga aaaaaacaac tccctgatga ttcaaggagt tgtctatagt
     5881 taaattagtt tttagaagct tcttggaatt ctggattttt ccatgcttcg tcaataatag
     5941 cttgcaattc tttagcagat gcttgcattt tttgagtttc tgcatcgttc aatggaatgt
     6001 ttactggacg aacgatacca tgtgcaccaa caacagctgg ttgaccgata aagacattct
     6061 caactccgta tagaccttct tggaatactg aaagtggaag tactgcgttt tcatcgtcaa
     6121 ggattgcttt agtgatacga gcaagggcta ctgcgatacc gtagtatgtt gcaccttttt
     6181 tgttgatgat tgtgtaggct gcatcacgaa caccttcgaa caattcaatc aattcagctt
     6241 cttgaacatt ttgagtgtct ttaaggaatt cttcaaggtt tacaccagcg atgttagcgt
     6301 gtgaccaaac agcgaactca gagtcaccgt gttcacccat gatgtaggcg tgcactgaac
     6361 gagcatccac atccaatttt tcagcaagtg cttgacggaa acgagctgag tcaagtgaag
     6421 tacctgaacc gataacgcgt tctttaggga aaccagagaa tttccaagtt gagtaagtca
     6481 aaacgtcaac tgggttagca gcaacaagga agataccttt gaaaccagat tcaacaactt
     6541 gagttacgat tgatttgttg atagcaaggt ttttacctac aaggtcaaga cgagtttcac
     6601 ctggtttttg aggtgcacct gcagtaatca caacaaggtc agcgtctgca cagtcagagt
     6661 attgagctgc atagattttt ttaggtgaag tgaaggcaag ggcgtgacta aggtcaagcg
     6721 catcaccaac agctttttca tgcaattgtg gaatttcgat aattccaagc tcttgtgcaa
     6781 ttccttggtt aacaagtgca aaagcgtaag atgaacctac agcaccatca ccgacaagga
     6841 taactttttt gtgttgttta gttgaagtca ttgttttaaa catctcctta attttattag
     6901 gggattttcc ctagacaact tcattctatc acttttaaaa aactttgtca cgaatatgcc
     6961 ttatagttct cgatgtaaac gttttagtgg tttagaggct gaaatagatg ggaatttatg
     7021 gtataatgtt gttacttact aattgtgaaa tgaggcattt attaatgcag gataaaaatt
     7081 tagtgaatgt caatctgaca aaggagatga aggcaagttt tatcgactac gccatgagtg
     7141 ttatcgtagc gcgagctctt cctgatgttc gagatggctt aaaacctgtt caccgtcgca
     7201 ttctctacgg aatgaatgaa ttgggtgtga ccccagacaa accccataaa aaatctgctc
     7261 gtattacagg ggatgtcatg ggtaaatatc acccacacgg ggattcctct atttatgaag
     7321 ccatggtccg tatggctcaa tggtggagct accgttacat gcttgtagat ggtcatggga
     7381 attttggttc catggatgga gatagtgctg ccgctcaacg ttataccgag gcacgtatga
     7441 gcaagattgc tctggaaatg cttcgtgata tcaacaaaaa tacagttgat ttcgttgata
     7501 actatgatgc caatgaacgg gaacccttgg tcttgccagc gcgttttcca aaccttttgg
     7561 ttaatggagc aactggtatc gcggttggga tggcaaccaa tattccacct cataatctgg
     7621 gtgaaaccat tgatgcagtg aagttggtca tggataatcc tgaagtgact accaaggact
     7681 tgatggaagt cttgcctgga ccagattttc caactggtgc tcttgtcatg gggaaatcag
     7741 gtatccataa ggcttatgaa acaggtaaag gttcgattgc cctacgttct cgtacagaga
     7801 ttgaaacgac taagactggt cgtgagcgca tcgttgtaac agaatttcct tacatggtca
     7861 ataaaaccaa ggtgcatgag catattgttc gcttggttca ggaaaaacgc attgagggta
     7921 tcacagcagt acgtgatgag tcaaaccgtg aaggtgttcg atttgttatt gaagtcaagc
     7981 gcgacgcctc agccaatgtt attctcaata acctcttcaa aatgacccaa atgcaaacca
     8041 attttggttt caatatgctc gctatccaaa atggtatacc gaaaattttg tctcttcgtc
     8101 agattttgga tgcttatatc gagcaccaaa aagaagtggt tgttcgtcgt acacgttttg
     8161 ataaggaaaa agcggaagcg cgcgctcata tcttagaagg tctcttgatt gcgctagacc
     8221 atatcgacga agtgattcgt atcatccgtg ctagtgaaac ggatgcggaa gctcaagctg
     8281 agttgatgag caagtttaag ctttctgaac gtcaaagtca agctatcctt gatatgcgtc
     8341 ttcgtcgttt gacaggtttg gaacgcgata agattcaatc tgagtatgat gacctcttgg
     8401 ctctgattgc ggatttagca gatattcttg ctaagcctga acgtgtttct caaattatca
     8461 aagacgaatt ggatgaagtt aaacgtaaat tttctgataa gcgccgtaca gagttgatga
     8521 ttggacaggt cttgagtctc gaggatgagg acttgattga agaatcggat gtcttgatta
     8581 ccctttctaa cagaggctac attaagcgtt tggatcagga cgagttcact gctcaaaaac
     8641 gtgggggtcg tggtgtccaa ggaacgggag tgaaagatga tgactttgtt cgtgagttag
     8701 tgtcaactag cacccatgat catctgctct tcttcacaaa caagggacgt gtctatcgtc
     8761 ttaaaggtta tgaaattcct gagtatggtc ggactgccaa agggctacca gtagtcaatc
     8821 tcttgaaatt ggatgaagac gaaagtattc agacggttat caatgttgag tctgatcgca
     8881 gtgatgatgc ttatctcttc tttacaaccc gtcacggtat tgtgaagaga accagtgtta
     8941 aggagtttgc caatattcgt caaaatggtc tcaaagcgct gaatttaaag gatgaagatg
     9001 agttaatcaa tgtcttgttg gcagaaggag atatggatat tatcattggt accaagtttg
     9061 gttatgcagt tcgctttaat caatcagccg ttcgtggtat gagtcgtatc gccactggtg
     9121 tgaaaggtgt taaccttcgt gaaggagaca cagttgttgg tgccagcttg attactgatc
     9181 aagatgaggt tcttattatc acagaaaaag gatatggtaa gcgtacagtc gctactgaat
     9241 acccaacaaa aggtcgtggt ggtaagggaa tgcagacagc taaaattacc gaaaaaaatg
     9301 gcttgctggc cggtcttatg actgttcaag gggatgagga tttgatgatt atcactgata
     9361 caggtgtcat gattcgaacc aatcttgcca atatttcaca aacaggacgt gcaactatgg
     9421 gagttaaagt aatgcgcctg gatcaagatg ctcagatagt gactttcaca acggttgcgg
     9481 tggcagaaaa agaagaagtt gggacagaaa acgaaacaga aggtgaagaa taatgtctca
     9541 aaaaaataat aaaaagaaaa acaagcgaaa aaatctgctg acaaatatcc tagcaggatt
     9601 tctgatatta ctgtcactgg ctttgatttt taatactcaa attcgaaata ttttcatagt
     9661 ctggaatacc aataagtatc aagttagcca ggtatcaaaa gaaaaattag aagaaaatca
     9721 ggatacagaa ggcaattttg actttgattc tgtcaaagct atctcttcgg aagctgttct
     9781 aacttctcaa tgggatgctc aaaaattacc agttattggg ggaattgcaa ttcctgaatt
     9841 ggaaatgaat ttgccgattt ttaaaggact tgataatgtt aatctcttct acggagctgg
     9901 tacaatgaaa cgcgagcaag taatgggaga aggaaattat agtctagcta gtcaccatat
     9961 ctttggtgtt gataatgcta ataaaatgtt attttctcct ttagataatg ctaaaaatgg
    10021 catgaagatt tatctaaccg ataaaaataa agtttatact tatgaaatac gtgaagtcaa
    10081 acgtgtgaca ccggatcgtg ttgatgaagt tgatgataga gatggggtca atgaaatcac
    10141 attagtaacc tgtgaagacc ttgctgctac agaacgtatt attgtcaaag gtgatttgaa
    10201 agaaacaaaa gattattcac aaacatctga tgaaattcta acagctttca atcaaccata
    10261 taaacaattt tattaataca aatcagtgaa atcatggatt tcactgattt tttaagattt
    10321 tcataaaaat atagtaaaat gaaataagaa taggacgaat cgttcaggac agtcaaatcg
    10381 atttctaaca atgttttaga agtagaggtg tactattcta gtttcaatct actataaact
    10441 tttatgaaat acagaaaacg cttcctaaaa cctaaagttt gtgatataat tatcaagaaa
    10501 aaagatttag gagtttatta tggtttcttc agaatttatc tcaaagattg aatttgcttg
    10561 caataagaaa gaaagtcttt atagtcaaag caaatttaag tatgcgattc gttcgatgtt
    10621 cgcaggtgca tttttaacct tcagtactgc tgcaggtgca gttggggctg acttgattaa
    10681 taaaattgca ccaggtagtg gacgcttcct ctttccattc gtttttgctt ggggcttggc
    10741 ctacattgtt tttttgaatg ccgagttggt cacttcaaac atgatgttct tgactgctgg
    10801 tagtttctta aaaaaaatct cttggagaaa aacagctgag attttactat actgtacctt
    10861 gttcaacctt atcggagcct tgatagcagg gtggggcttt gctcattcgg cagcctatgc
    10921 gaatctgaca cacgatagtt tcatctcagg tgttgttgag atgaagttag gccgctcaaa
    10981 tgaattggtc ttgcttgagg cgattttggc aaatattttc gtaaatattg cgattctgtc
    11041 atttattttg gtcaaagatg gtggtgccaa actttggctt gtgttgtcag ctatttacat
    11101 gtttgtattc ttaacaaacg agcacattgc ggcgaacttt gcttctttcg cgattgtgaa
    11161 attcagtgtt gctgcggatt caattgccaa cttcggtgtt ggaaatatgc ttcgccactg
    11221 gggtgtgact ttcatcggaa actttatcgg aggaggcctc ttgatgggtc ttccatatgc
    11281 cttcctcaat aaaaacgaag atacttatgt agattaagaa aatgagcacg attgagtcgt
    11341 gcttttttca ttttcaaaat aaggtaatag ctatttctta tatcaaaata tagaaaactg
    11401 atatttgtaa actataactc aaggtgctac aatatcctta ataaaatgat atggaggtca
    11461 ccttatgact tgtgatttta aatttgaaac tctacaacta catgctggtc aagttgtggc
    11521 tccagctact aagtctcgtg cagtgccgat ttatcaaaca acatctttta tttttgatga
    11581 cacgtaggaa ggtgctgatc tgtttgcctt gaggaaacca gggaacattt atactcgtat
    11641 caccaatcct acaacagctg cccttgaagg tggtgttgaa gcgctagcaa cagcatcagg
    11701 tatgactgca gtgacttata cgattttggc gcttgcccat gctggtgacc atgtagtggc
    11761 tgcttcgact atttacggtg gaaccttcaa tcttttgaaa gaaccccttc ctcgttatgg
    11821 tatcacaaca acctttgtcg atgttgataa tttggaggaa gtagaagcag ctatcaaaga
    11881 caataccaag cttgtcttga ttgaaacctt gggtaactcc ttgattaata ttccagacct
    11941 ggaaaaactg gcagagattg ctcataaaca tcaaatccca cttgtgtcag acaatacttt
    12001 tgcaatacct tatttgatta acgtcttctc tcatggcgtt gacattgcca ttcactctgc
    12061 gactaagttt atcggtgggc atggtacaac tattggagga ataattgtcg atagtggtcg
    12121 ttttgactgg acggcttcag ggaaattccc tcaatttgtt gacgagggtc caagctgcca
    12181 caatttgagt tatacttgtg atgtgggtgc agcagccttt attatagctg ttcgagttca
    12241 attgcttcgt gatacaggtg cagccttgtc accattcaat gctttcctct tgctacaaag
    12301 acttgaaacc tcttcacttc gtgtggaacg ccatgtacaa aatgctgaga caattgttga
    12361 ttttcttgtc aaccatccta aggtagaaaa ggtaaattat ccaaaacttg cagatagtcc
    12421 ttatcatgcc ttggctgaga aatacttgcc aaaagatgtc ggttcaatct ttaccttcca
    12481 tgtcaaaggt ggcgaggaag aagcacgcaa ggtcattgat aatttagaaa tcttttctga
    12541 ccttgcaaac gcggcagatg ctaaatcgct tgttgtccat ccagcaacaa ccactcacgg
    12601 tcaattgtca gaaaaagacc tagaagcagc aggtgtcaca ccaaactaaa ttcgtttgtc
    12661 aatcggtctt gaaaatgtag aagatttgat tgaagacttg cgcttggcct tggaaaaaat
    12721 ttaaagtaaa agaagataaa cagtgggctt cgactcactg tttttgattt tccctcaggc
    12781 atgatataat ggttaaagaa gtctagaaag aggaacgata tgaacgaaat caaatgtccc
    12841 aactgtgggg aagtctttac agtaaatgag agtcagtatg ccgaactctt gtcccaagtg
    12901 agaacggcag agtttgataa ggaactacac gataggatga agcaggaact ggccttggct
    12961 gagcaaaagg ccatgaatga gcaacagact aaactggctc agaaggatca agaaattgcg
    13021 caattacaga gtcagatcca aaactttgat acagaaaaag aattggccaa gaaagaggtt
    13081 gaacagacaa gccatgaggc tctcttggct aaggacaagg aagtacagct cttagaaaat
    13141 cagttggcta ccttgcgttt ggagcatgaa aatcaactgc aaaagaccct ttctgaccta
    13201 gaaaaagaac gggatcaggt taaaaaccaa ctacttttgc aggaaaagga aaatgaatta
    13261 tctttggctt ctgttaagca aaactacgaa gcccagctca aggcagctag tgaacaagtc
    13321 gagttttata aggattttaa ggctcaacaa tctacaaaag cgattgggga aagcctagaa
    13381 cagtatgcag agagtgagtt taacaaggtt cgtagtttcg cctttccaaa tgcttacttt
    13441 gagaaggata acaaggtctc ttcgcgtggg tctaaagggg actttatctt ccgtgagtgt
    13501 gatgaaaatg gagttgaaat catttctatc atgtttgaga tgaaaaacga agcagacgga
    13561 acagagaaga agcacaagaa tgcagatttt tacaaggaat tggacaagga ccgtcgggag
    13621 aagaactgtg agtatgccgt tttggtgacc atgcttgagg ccgataatga ctactttaac
    13681 acagggattg ttgacgtcag ccacgagtat gaaaaaatgt atgttgttcg tcctcaattc
    13741 tttatccagt tgattggtct cttacgtaat gcggcgctaa attccctaaa atacaagcag
    13801 gagttggcct tggttcgcga gcaaaatatt gacattacgc attttgagga agacttggat
    13861 gcctttaagc tagcttttgc taagaactat aattcagctt cgactaactt tggaaaagct
    13921 attgatgaaa tcgacaaggc catcaaacgc atggaagagg ttaagaaatt cctgactaca
    13981 tctgaaaacc aactccgtct agctaacaac aaattggaag atgtctctgt taaaaaattg
    14041 acccggaaaa atccaacaat gaaagcgaag ttcgaagcac tgaaggggga gtagaaagca
    14101 aaaatgaacg gtattatcaa cttaaaaaaa gaagcaggaa tgacctcgca tgatgcggtt
    14161 tttaaactgc gtaagatttt gggaaccaag aaaattggtc atggtggaac cttggatccg
    14221 gatgtggtgg gtgttttgcc gattgcggtt ggcaaggcga cacgcatggt cgagtttatg
    14281 caggacgagg gtaagatcta tgagggggaa atcattctgg gctattccac gacgactgag
    14341 gatgctagtg gggaagtggt cgcagaaacc cctgttttgt ctcccttgga tgaaaagctt
    14401 gttgatgaag cgattgctag cttgactggg cctattactc agattccccc tatgtattcg
    14461 gcagttaagg ttaatggtcg caagctctat gagtatgcgc gtgctggtca ggaagtggag
    14521 cgtccagaac gtcaggtgac catttatcaa tttgagcgaa caagtccgat ttcttatgat
    14581 ggccaacttg cccgattcac ttttcgtgta aaatgcagta aagggactta catccgtact
    14641 ttgtcagttg atttgggtga aaagcttggt tatgcggctc atatgtccca tttgactcgt
    14701 actagtgctg ctggcttaca attagaagac gctcttacct tggaggaaat tgctgaaaaa
    14761 gtagaggctg ggcaattaga ttttctccat cctttagaga ttgggacagg tgaccttgtc
    14821 aaagttttcc taactccaga agaggctaca gaagttcgct ttggtcgttt tattgagcta
    14881 gaccaaacgg acaaagaact ggctgccttt gaagatgata aattgttagc cattctagaa
    14941 aaacggggca atctctataa gccaaggaag gtttttagct agatcgttta ggaataaaaa
    15001 tcgggtgata gataacaatt gcttgataaa cccccatact aatagtagaa tggttttggg
    15061 aattataata ttccaattgt tgcgagttgt agatactcaa ataatctata tagaaattta
    15121 gaggtgtgaa atgaagcaac ttaaaattct ttcagataaa tatttagagt ccatgacagg
    15181 ttctggtggg aacttaggtc taggatttgg tgtgataatt ccatgatgtg aaatgagttt
    15241 cgagaaaggg tggagcaact tcttcaacaa aaagaaataa atgaaaatag tgagttgagt
    15301 cacctgtttc gtcttgctat acaaaattta gacagaaatg aaaaatacca atcggtcatg
    15361 gccaatttga gtcaagggtt gtcactttac ctcatgacgc atcattacca ggcacctaag
    15421 tctgtcattg attttggttt atggattgcc aaagctccta gccaggaaag agggagactg
    15481 gctttcttgc agatgcttgc tcaaacccta cagggctttc gttaaaactg tcgaacatca
    15541 gagggaagac tctggtgttt tttgctgatg agactataaa ttttgtaaaa aatgtgatag
    15601 aatagacgac ggataaaata acggaggata gcatgcaaaa tagaccaatc attattggag
    15661 tgacaggtgg ttctggtggt ggtaaaacca gtgtttcaag agccatttta tcgcattttc
    15721 ctgatgaaaa gatttccatg attgagcatg attcatacta caaggatcag tctcatttga
    15781 cctttgaaga gcgtgtcaaa accaactatg accatccttt tgcctttgat acagacttga
    15841 tgatcgagca gattaaggaa ttgttggcag ggcgtccggt ggacatcccg acctacgact
    15901 atacagagca tacacggagt agcaagacct atcgtcagga gcctcaagat gtctttatcg
    15961 ttgagggcat tttggtcttg gaggacaagc gtctgcgcga tttgatggat atcaagattt
    16021 ttgtggatac ggatgacgat gtgcgtatta ttcgtcgtat caagcgtgat atggaggaac
    16081 gtggccgtag ccttgatagc gttattaacc agtacttagg tgtggtcaaa ccaatgtacc
    16141 accagtttat cgagtcaact aagcgttatg ctgatatcgt cattcctgaa ggggttagca
    16201 ataccgtggc tatcgacctg ttgacgacca agattgcaaa gattttggaa gaagctcgaa
    16261 acagcaaata atcacatgtg gaggccttgc ctcctttttc tatttttccc tcataatggt
    16321 acataaatgg agatttttag gcatattttt ggtataataa tacccataaa agagcaagta
    16381 aatgaatagt aggtggagat ggaaaagtat ttatcggtaa caactttgac caaatatctg
    16441 aaaatgaaat tcgataaaga cccatacttg gaacgggtct atttaactgg tcaagtttcc
    16501 aactttcgta aacgacctac tcaccaatat ttctccctaa aggatgacca tgcagttatt
    16561 caagcgacca tctggtctgg gatttatcag aaattagggt ttgacctgga agaaggaatg
    16621 aagatcaatg tgattgggcg tgtacaggtc tatgaaccaa gtggtagcta ctccatcatc
    16681 attgaaaaag ctgagcctga tggggttggg gcgcttgcga ttcagtttga acaacttaag
    16741 aaaaaattga cagaagaagg cctgtttcaa gaacgcttca agcaagctct accccaattt
    16801 tctaagagaa ttggggtagt aaccagccgt agtggagccg ttattcgaga tattatcacg
    16861 accgtcagca ggcgattccc aggtgttgac atccttcttt atcctaccaa ggttcaaggt
    16921 gaaggggctg cggaggaaat tgctagaaat attgcgcgtg ctaatcaacg ggacgatttg
    16981 gatttgctca ttattggtcg tggaggtggt tctattgagg atctctgggc ctttaacgaa
    17041 gaaattgtgg tacgagctat ttttgaatct cgtttgccag ttatctctag tgtggggcat
    17101 gagacggatg tgaccttggc agattttgtg gcagatcgac gcgctgcaac gccaacagcg
    17161 gcggctgaac tggcaacacc tgtgaccaag ttggatgtat tagctcattt gcaaaatcag
    17221 gaaaaacgga tggcaacggc agtccgaaat gttctatcta agaaacaaga ggctttgaaa
    17281 aaatgcagtc agtctgttat ctttagacaa cctgagcgct tgtatgacgg ttatttgcaa
    17341 cgcttggacc aactgcaact gcgtttgaaa caaagtttgc gaactcggat ttctgataac
    17401 aaacaattag ttcaagcaag aactcatcaa ttagtacaat tatcacctgt taccaaaatc
    17461 caacgctatc aagaccgttt aggacagttg gacaagctct taggtagcca aatggcgtta
    17521 gtttatgacg ccaaggttgc tgaggccaag cgactttcgg aagctttgct catgttggat
    17581 actagccgaa tcgtggcgcg tggttatgct attgtcaaaa aagaagagtc cgttgtagat
    17641 tcggttgaga gtttgaagaa aaaagaccaa gtaacgcttt tgatgcgaga tggtcaagta
    17701 gaattagagg ttaaagatgt caaaacaaaa gaaatttgag gaaaatctag cagaactgga
    17761 aaccattgtc caaagtttgg aaaatggtga aattgctctg gaagatgcga ttactgcctt
    17821 tcaaaagggc atggtcttgt caaaagagct ccaagctacg ctggacaagg ctgaaaagac
    17881 cttggtcaag gtcatgcaag aagacggaac agaaagtgat tttgaatgaa aaagcaagaa
    17941 aaattagctc ttgtcgagtc ggctttggaa gatttttatg gagaccagca gtttgcctct
    18001 agtttacggg agtctgttct ctattctatt catgctggtg gcaagcgtat tcggcctttt
    18061 ctcttgttag aagttctgga atccttgcag gttaccatca aacctgctca cgcgcaggta
    18121 gctactgcct tggagatgat tcatacaggg agcttgattc acgatgacct tcctgctatg
    18181 gatgatgacg attatcgaag agggcggtta accaatcaca agaaattcgg tgaagctatg
    18241 gccattttgg ctggagatgc cttattctta gacccatatg ccttgattgc gcaggcagat
    18301 ttgccaagtc agatcaaggt ggacttgatt gccaacttat cccttgcttc aggtagtctg
    18361 ggtatggtgg cagggcaagt tttggatatg gagggcgaac accagcactt gtctctggaa
    18421 gaacttcaga ctattcatgc caataagact gggaagttac tagcctatcc cttccaagcg
    18481 gcagctatta tagctgaatt gtcacctgaa atgcaggtga agctgaaaac tgtgggtgaa
    18541 ttgattggac ttgcttttca agtcagagat gatgtactgg atgtgacagc tagttttgag
    18601 gaaatcggca agacacctca aaaggatctg caggcagaaa aatcaaccta tcctgccttg
    18661 ttgggcttgg aagagtccat tgccttttgt aaccaaaccc tggatcaagc taatgaaaaa
    18721 ttagaagaaa ttgcccagca gcttcccttt gaaacagaat cgattgtaag tgtagtagaa
    18781 agtttgagaa tcaatggcta aggaaagagt ggatgtacta gcttataaac aggggttgtt
    18841 tgaaacgaga gagcaggcca agcgaggtgt gatggctggt ctagtcgtag cagtccttaa
    18901 tggagaacgg tttgacaagc caggagagaa aattccagat gacaccgaat taaaactcaa
    18961 gggggagaaa ctcaagtatg tcagccgtgg tggtttgaaa ctggaaaagg ccttgcaggt
    19021 ctttgatttg tcggtggatg gcgcgactac gattgatatc ggggcctcta ctggaggttt
    19081 taccgatgtc atgctacaga atagtgccaa gttggtcttt gcagtcgatg ttggtaccaa
    19141 tcagttggct tggaaattac gccaagaccc acgagttgtc agcatggagc agttcaattt
    19201 tcgctatgct gaaaagactg atttcgagca ggagccgagc tttgccagta ttgatgtgag
    19261 tttcatttcc cttagtctga ttttgccagc cttgcacagt gtcttggctg atcaaggtca
    19321 ggtggtagca cttgtcaaac ctcagtttga ggcaggacgt gagcagattg ggaaaaatgg
    19381 aattattcga gatgctaaga ttcatcagaa tgtccttgaa tctgtaacag ctatggcagt
    19441 agaggcaggt ttttcagtcc ttggcttgga cttttctccc atccaaggtg gacatggaaa
    19501 tattgaattt ttagcgtatt tgaaaaaaga aaagtcagca agcaatcaga ttcttgctga
    19561 gattaaagaa gcagtagaga gggcgcatag tcaatttaaa aatgaataaa aaagaaagac
    19621 ttgaaaaaat tagaagattg gtgacagatt atcaaatcgg cacgcaagaa gaaattgtag
    19681 aacatttgaa agaagcaggt atcactgcca ctcaggcgac ggtatcccga gatatcaaag
    19741 agttaggtat tgtcaaaatt cctttgagag acaacaccta tgtctacgaa ttgccaaaat
    19801 caatcgtaaa aagtctgcaa ctggctgaag acaatatcga atcggctgaa ttgatggata
    19861 agatgatcaa tctccaagtt attccaggaa atacggcttt tgtaaaagct cagttaatcg
    19921 agacttttgc agacaagatt tttagctgtt tgactgatga tagctcgatt ttagtcattg
    19981 ccagaagtgg aagtctagca gaggaaatct ttgaacaagt aaaaaattgg taggtctata
    20041 tgttacttga aatttcgata aaaaactttg ccattattga ggctatttcc ctcaattttg
    20101 aaaaggggat gactgtcctg actggtgaaa cgggtgcagg gaagtcgatt atcattgatg
    20161 ccatgaatat gatgttggga gctcgtgcga cgacagatgt tattcgtcat ggtgcaccaa
    20221 aggcagagat tgaggggctt ttctcagttg agaatagtcg tcttttacag gaaatttttg
    20281 atgagcaagg tttagaatta ggtgatgaaa ttatcatccg tcgggaaatc ttgcaaaatg
    20341 gtcgtagtat cagccgtgta aatggtcaga tggttaatct gtctgttttg cgaactattg
    20401 ggcaacatct tgtagatatt catggtcagc atgaccatga ggagttaatg cgtccccaac
    20461 tgcatatcca gatgttggat gaatttggtg atgccgcttt ttgggacttg aaagaaacct
    20521 atcaaacgag ttttgatgcc tatcggaaaa tgcgcaagca ggttctggaa gtcaagaaaa
    20581 accaacagga acacaaggca cgtatcgaaa tgttggaatt tcaaatggca gagattgagg
    20641 cagcaaactt gcaggctgga gaagacttgg atctcaatca agagcgagat aaactcctca
    20701 accacaaaaa tattgcggat acactgacca atgcctacag tatgttggac aatgaagatt
    20761 tttcaagtct ggccaatgtt cgttcagcca tgaatgacat ggaaagtgtc gaagagtatg
    20821 accctgaata ccgtgaaatt tcaagctctc tgtctgagac ctactatgtt ttagaagaca
    20881 ttagcaaacg tttggaagct atcattgagg accttgattt tgatggcaat cgcctcatgc
    20941 aggttgagaa tcgtttggac ctccttcata ctattactcg taagtatggt gggactgttg
    21001 atgatgtttt gctttatttt gccaagatta cggaagaata caatctcttg acaggcaata
    21061 atctttcgtc tgaggacatg gaagcagagc ttaagaagtt ggaagtcaat cttgtcaatt
    21121 tggcaggtca acttgcttct gctcgtcata atttggctca gcaactcgaa gctgagatta
    21181 aacaagaact gcaagatctt tatatggaaa aagcccagtt tcaggttcgt tttagtaagg
    21241 gaaaattcag tcgtgaggga aataaaatgg ttgagtttta tatttcaacc aaccctggag
    21301 aagactttaa acccttggtt aaggttgctt ctggagggga attatctcgt ctcatgttag
    21361 ccattaagtc tgccttttca cgtaaagaag gcaagactag cattgtcttt gatgaggtgg
    21421 atacgggagt ttcaggtcgt gttgctcaag ctattgctca gaaaattcat aaaattggtc
    21481 agcatggtca ggttttggct atctcccatt tgccacaagt aattgcgatt gcagattatc
    21541 aattctttat tgagaagatt agtaatgacc attcaacggt ttcgactgtt cgtctcttga
    21601 cggtcgaaga gcgagtggag gaagttgcca agatgttggc aggtgatgat gtgacagaag
    21661 cagccctgac gcaagcaaga gaattgttga gaaacaggga gaaataagat gacagattat
    21721 tatgtaattg gagatgttca cggaaaagct gggatgctgg aagaccttct caaaacctgg
    21781 gatggtcagc cccagttgct ctttctaggt gatttgattg acagaggtga ggatagtcac
    21841 cgtgttcttg aaatggtcaa ggacttggtg gacaatcaag gggctatctg tttgtccgga
    21901 aaccacgagt atatgttttt gacttggcta gatgacccag aagaaagtta tgaccattat
    21961 agtcgcaatg gtggagatac aaccattaac tctatcctag gtcgtccctt ggatgcacca
    22021 gttgatggag tagaagatgc caagcgggtt gccgctgaag cggcagactt ggtcgaattc
    22081 attcgtcaaa tgccatttgt agtagagaca gacaagtata tctttgttca cgcaggtatt
    22141 gatttgacct tggacgactg gcatgaaaca acagattata aaaaagtatg gcttagaaaa
    22201 ccattccacg gagctgaaaa tcatactgga aaaaccattg tcttcggtca tacaccggtc
    22261 tatggtttat tacagcaaga acgcggtaca tctgagcttt ggactacaga agatggcaag
    22321 attggaatgg atggaggagc tgtttatggt ggtgtccttc acgggattgt ctttacagac
    22381 caaggaatga cagaacacca ctttatcgaa aatgacggct ttgtcgctga agattagtac
    22441 tcctagcagg gtatggtctt gtcaaaatat caaaaacaat ttataataaa tagataccct
    22501 gaaaggaaga gaatcatgaa cttagaagaa ttgaaaaaac gacaggagaa gatccgtaac
    22561 ttctctatta tcgcccatat tgaccacgga aaatcaactc tagcagaccg cattttggaa
    22621 aaaacagaga cggtttcaag tcgtgaaatg caggcccagc ttttggatag catggagcta
    22681 gagcgggaac gtggaattac tattaagttg aatgccatcg agttgaatta cactgcaaaa
    22741 gatggggaaa cttatatttt ccacttgatt gacacaccag ggcacgttga ctttacctat
    22801 gaagtttcac gttcgctagc tgcctgtgag ggtgctattt tggtggtcga tgcggctcaa
    22861 ggaattgagg ctcaaactct tgccaacgtt tatctggctt tggataatga tttggaaatc
    22921 atgcctatca ttaataaaat tgacctgccg gctgcagatc cggagcgcgt gcgtacagag
    22981 attgaagatg tgattggttt ggatgccagt gaagcagttt tggcttctgc caaggctggt
    23041 attgggattg aagaaatcct cgagcaaatt gtagaaaaag taccagcacc aacgggtgat
    23101 gtgacggcgc cacttaaggc cttgattttc gactctgttt acgatgctta ccgtggggtt
    23161 atcctccaag tgcgtgtcat ggacggagtg gtcaaacctg gtgataagat tcagctcatg
    23221 agcaatagta agacctttga tgtggccgaa gtcggtattt ttacaccaaa agcggttggt
    23281 cgtgatttcc ttgcgactgg tgatgttggt tacattgcgg cgtctatcaa gacggttcag
    23341 gatactcgtg tgggtgatac cgttaccttg gcaaccaatc ctgcggcaga accattacat
    23401 ggttataagc agatgaatcc tatggtcttt gcgggtctct acccaatcga atcaaacaag
    23461 tacaatgacc tgcgtgaagc gcttgaaaaa ttgcaactga atgatgctag tcttcagttt
    23521 gaaccagaaa catctcaggc acttggattt ggtttccgtt gtggatttct tggacttctc
    23581 catatggatg ttatccagga acgtttagag cgtgagttca atattgacct catcatgaca
    23641 gctccgtctg ttatttacaa agttaatttg accgacggtg agtctatgga tgtgtctaac
    23701 ccatctgagt ttccagaccc aactaagatt gcgaccattg aagagcctta tgtcaaggcg
    23761 caaatcatgg taccacagga gttcgtcgga gcagtaatgg agctagctca gcgtaagcgt
    23821 ggggactttg tgactatgga ctatattgat gataaccgtg tcaatgttat ctatcaaatt
    23881 cctcttgctg aaattgtctt tgacttcttt gataaactta agtcttcgac acgtggttat
    23941 gcaagctttg actacgaatt gtcagaatat cgcccatcta agctggtgaa aatggatatt
    24001 cttctcaatg gagataaggt ggatgccctc agctttatcg ttcacaagga ctttgcctac
    24061 gaacgtggga aactcatcgt tgataaactc aagaaaatca tccctcgcca acaatttgaa
    24121 gttccaatcc aagcggctat tggacacaag attgtcgctc gtactgatat caaggccctt
    24181 cgtaagaacg tacttgctaa atgttatggt ggtgacgttt ctcgtaagcg taaactcctt
    24241 gaaaaacaaa aagctggtaa gaaacgcatg aaatccatcg gatcagttga agttccgcaa
    24301 gaagccttcc tcagcgtctt gagtatggat gaagaataag ttatcagaaa tgcctttcct
    24361 tgttcacagg aaatttataa gaatcaatag taaagcaggc ttagatggtc tgctttttta
    24421 gtttttatac tcttcgaaaa tctcttcaaa ccacgtcagc gtcgccttac cgtatgtatg
    24481 gttactgact tcgtcagttt catctacaac ctcaaaacca tgttttgagc tgacttcgtc
    24541 agtttcatct acaacctcaa aactgtgttt tgaacaacct gcggctagct tcctagtttg
    24601 ctctttgatt ttcattgagt attagaacag aaaaaatgct tggagtattt gtttgtgtgt
    24661 ttacttttat ataacaaact ataaacacaa caaaaatata aaaaaagaga caaaaaagaa
    24721 cagaaagtaa ttaacaacga tttcatatag tgttatactt atagcataaa gttaatggaa
    24781 agaagggaaa accttatggt attagattat ttctttgaca aaaaccttgt gttttgctta
    24841 gaagcggata atcaagaata actctttgat caggtagcaa gcttgttgga ggaacgagaa
    24901 attgt
//
LOCUS       DAVBEO010000031        24327 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 009
            SAMEA1678075-rid20185393.denovo.031, whole genome shotgun sequence.
ACCESSION   DAVBEO010000031 DAVBEO010000000
VERSION     DAVBEO010000031.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678075
            Sequence Read Archive: ERR226392
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 24327)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24327)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980207.1
            Genome Coverage       :: 150x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:50:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 72 of 147
            Pseudo Genes (incomplete)         :: 72 of 147
            Pseudo Genes (internal stop)      :: 42 of 147
            Pseudo Genes (multiple problems)  :: 32 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24327
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678075-rid20185393.denovo.031"
                     /strain="KS 009"
                     /db_xref="taxon:1313"
     gene            complement(<1..618)
                     /locus_tag="VQ543_001276"
     CDS             complement(<1..618)
                     /locus_tag="VQ543_001276"
                     /EC_number="2.7.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001050429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylate kinase"
                     /protein_id="HET2611996.1"
                     /translation="MNLLIMGLPGAGKGTQAAKIVEQFHVAHISTGDMFRAAMANQTE
                     MGVLAKSYIDKGELVPDEVTNGIVKERLSQDDIKETGFLLDGYPRTIEQAHALDKTLA
                     ELGIELEGIINIEVNPDSLLERLSGRIIHRVTGETFHKVFNPPVDYKEEDYYQREDDK
                     PETVKRRLDVNIAQGEPIIAHYRAKGLVHDIEGNQDINDVFSDIEK"
     gene            complement(769..2079)
                     /gene="secY"
                     /locus_tag="VQ543_001277"
     CDS             complement(769..2079)
                     /gene="secY"
                     /locus_tag="VQ543_001277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecY"
                     /protein_id="HET2611997.1"
                     /translation="MFFKLLREALKVKQVRSKILFTIFIVLVFRIGTSITVPGVNANS
                     LNALSGLSFLNMLSLVSGNALKNFSIFALGVSPYITASIVVQLLQMDILPKFVEWGKQ
                     GEVGRRKLNQATRYIALVLAFVQSIGITAGFNTLAGAQLIKTALTPQVFLTIGIILTA
                     GSMIVTWLGEQITDKGYGNGVSMIIFAGIVSSIPEMIQGIYVDYFVNVPSSRITSSII
                     FVIILIITVLLIIYFTTYVQQAEYKIPIQYTKVAQGAPSSSYLPLKVNPAGVIPVIFA
                     SSITAAPAAILQFLSATGHDWAWVRVAQEMLATTSPTGIAMYALLIILFTFFYTFVQI
                     NPEKAAESLQKSGAYIHGVRPGKGTEEYMSKLLRRLATVGSLFLGVISILPIAAKDVF
                     GLSDVVAFGGTSLLIIISTGIEGIKQLEGYLLKRKYVGFMDRTE"
     gene            complement(2092..2532)
                     /gene="rplO"
                     /locus_tag="VQ543_001278"
     CDS             complement(2092..2532)
                     /gene="rplO"
                     /locus_tag="VQ543_001278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004225266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L15"
                     /protein_id="HET2611998.1"
                     /translation="MKLHELKPAEGSRKVRNRVGRGTSSGNGKTSGRGQKGQKARSGG
                     GVRLGFEGGQTPLFRRLPKRGFTNINAKEYAIVNLDQLNVFEDGAEVTPVVLIEAGIV
                     KAEKSGIKILGNGELTKKLTVKAAKFSKSAEEAITAKGGSVEVI"
     gene            complement(2677..2901)
                     /gene="rpmD"
                     /locus_tag="VQ543_001279"
     CDS             complement(2677..2901)
                     /gene="rpmD"
                     /locus_tag="VQ543_001279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012386624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L30"
                     /protein_id="HET2611999.1"
                     /translation="MVFQFLIWHKKGDKMAQIKITLTKSPIGRIPSQRKTVVALGLGK
                     LNSSVIKEDNAAIRGMITAVSHLVTVEEVN"
     gene            complement(2873..3367)
                     /gene="rpsE"
                     /locus_tag="VQ543_001280"
     CDS             complement(2873..3367)
                     /gene="rpsE"
                     /locus_tag="VQ543_001280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S5"
                     /protein_id="HET2612000.1"
                     /translation="MAFKDNAVELEERVVAVNRVTKVVKGGRRLRFAALVVVGDHNGR
                     VGFGTGKAQEVPEAIRKAVDDAKKNLIEVPMVGTTIPHEVLSEFGGAKVLLKPAVEGS
                     GVAAGGAVRAVVELAGVADITSKSLGSNTPINIVRATVEGLKQLKRAEEIAALRGISV
                     SDLA"
     gene            complement(3385..3741)
                     /gene="rplR"
                     /locus_tag="VQ543_001281"
     CDS             complement(3385..3741)
                     /gene="rplR"
                     /locus_tag="VQ543_001281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L18"
                     /protein_id="HET2612001.1"
                     /translation="MISKPDKNKLRQKRHRRVRGKLSGTADRPRLNVFRSNTGIYAQV
                     IDDVAGVTLASASTLDKEVSKGTKTEQAVAVGKLVAERANAKGISEVVFDRGGYLYHG
                     RVKALADAARENGLKF"
     gene            complement(3825..4361)
                     /gene="rplF"
                     /locus_tag="VQ543_001282"
     CDS             complement(3825..4361)
                     /gene="rplF"
                     /locus_tag="VQ543_001282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L6"
                     /protein_id="HET2612002.1"
                     /translation="MSRIGNKVIVLPAGVELANNDNVVTVKGPKGELTREFSKDIEIR
                     VEGTEITLHRPNDSKEMKTIHGTTRALLNNMVVGVSEGFKKELEMRGVGYRAQLQGSK
                     LVLAVGKSHPDEVEAPEGITFELPNPTTIVVSGISKEVVGQTAAYVRSLRSPEPYKGK
                     GIRYVGEFVRRKEGKTGK"
     gene            complement(4553..4951)
                     /gene="rpsH"
                     /locus_tag="VQ543_001283"
     CDS             complement(4553..4951)
                     /gene="rpsH"
                     /locus_tag="VQ543_001283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009754342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S8"
                     /protein_id="HET2612003.1"
                     /translation="MVMTDPIADFLTRIRNANQAKHEVLEVPASNIKKGIAEILKREG
                     FVKNVEIIEDDKQGVIRVFLKYGPNGEKVITNLKRVSKPGLRVYKKREDLPKVLNGLG
                     IAILSTSEGLLTDKEARQKNVGGEVIAYVW"
     gene            complement(5236..5505)
                     /gene="rpsN"
                     /locus_tag="VQ543_001284"
     CDS             complement(5236..5505)
                     /gene="rpsN"
                     /locus_tag="VQ543_001284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HET2612004.1"
                     /translation="MAKKSMVAREAKRQKIVDRYAEKRAALKAAGDYEGLSKLPRNAS
                     PTRLHNRCRVTGRPHSVYRKFGLSRIAFRELAHKGQIPGVTKASW"
     gene            complement(5523..6065)
                     /gene="rplE"
                     /locus_tag="VQ543_001285"
     CDS             complement(5523..6065)
                     /gene="rplE"
                     /locus_tag="VQ543_001285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L5"
                     /protein_id="HET2612005.1"
                     /translation="MANRLKEKYLNEVVPALTEQFNYSSVMAVPKVDKIVLNMGVGEA
                     VSNAKSLEKAAEELALISGQKPLITKAKKSIAGFRLREGVAIGAKVTLRGERMYEFLD
                     KLVSVSLPRVRDFHGVPTKSFDGRGNYTLGVKEQLIFPEINFDDVDKTRGLDIVIVTT
                     ANTDEESRALLTGLGMPFAK"
     gene            complement(6089..6394)
                     /gene="rplX"
                     /locus_tag="VQ543_001286"
     CDS             complement(6089..6394)
                     /gene="rplX"
                     /locus_tag="VQ543_001286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011921687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L24"
                     /protein_id="HET2612006.1"
                     /translation="MFVKKGDKVRVIAGKDKGTEAVVLTALPKVNKVIVEGVNIVKKH
                     QRPTNELPQGGIIEKEAAIHVSNVQVLDKNGVAGRVGYKFVDGKKVRYNKKSGEVLD"
     gene            complement(6472..6840)
                     /gene="rplN"
                     /locus_tag="VQ543_001287"
     CDS             complement(6472..6840)
                     /gene="rplN"
                     /locus_tag="VQ543_001287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012727667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L14"
                     /protein_id="HET2612007.1"
                     /translation="MIQTETRLKVADNSGAREILTIKVLGGSGRKFANIGDVIVASVK
                     QATPGGAVKKGDVVKAVIVRTKSGARRADGSYIKFDENAAVIIREDKTPRGTRIFGPV
                     ARELREGGFMKIVSLAPEVL"
     gene            complement(6866..7126)
                     /gene="rpsQ"
                     /locus_tag="VQ543_001288"
     CDS             complement(6866..7126)
                     /gene="rpsQ"
                     /locus_tag="VQ543_001288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S17"
                     /protein_id="HET2612008.1"
                     /translation="MERNNRKVLVGRVVSDKMDKTITVVVETKRNHPVYGKRINYSKK
                     YKAHDENNVAKEGDIVRIMETRPLSATKRFRLVEVVEEAVII"
     gene            complement(7151..7357)
                     /locus_tag="VQ543_001289"
     CDS             complement(7151..7357)
                     /locus_tag="VQ543_001289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006739716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L29"
                     /protein_id="HET2612009.1"
                     /translation="MKLNEVKEFVKELRGLSQEELAKRENELKKELFELRFQAATGQL
                     EQTARLKEVKKQIARIKTVQSEAK"
     gene            complement(7367..7780)
                     /gene="rplP"
                     /locus_tag="VQ543_001290"
     CDS             complement(7367..7780)
                     /gene="rplP"
                     /locus_tag="VQ543_001290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003029477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L16"
                     /protein_id="HET2612010.1"
                     /translation="MLVPKRVKHRREFRGKMRGEAKGGKEVAFGEYGLQATTSHWITN
                     RQIEAARIAMTRYMKRGGKVWIKIFPHKSYTAKAIGVRMGSGKGAPEGWVAPVKRGKV
                     MFEIAGVSEEIAREALRLASHKLPVKCKFVKREAE"
     gene            complement(7784..8437)
                     /gene="rpsC"
                     /locus_tag="VQ543_001291"
     CDS             complement(7784..8437)
                     /gene="rpsC"
                     /locus_tag="VQ543_001291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000529931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S3"
                     /protein_id="HET2612011.1"
                     /translation="MGQKVHPIGMRVGIIRDWDAKWYAEKEYADYLHEDLAIRKFVQK
                     ELADAAVSTIEIERAVNKVNVSLHTAKPGMVIGKGGANVDALRAKLNKLTGKQVHINI
                     IEIKQPDLDAHLVGEGIARQLEQRVAFRRAQKQAIQRAMRAGAKGIKTQVSGRLNGAD
                     IARAEGYSEGTVPLHTLRADIDYAWEEADTTYGKLGVKVWIYRGEVLPARKNTKGGK"
     gene            complement(8450..8794)
                     /gene="rplV"
                     /locus_tag="VQ543_001292"
     CDS             complement(8450..8794)
                     /gene="rplV"
                     /locus_tag="VQ543_001292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L22"
                     /protein_id="HET2612012.1"
                     /translation="MAEITSAKAMARTVRVSPRKSRLVLDNIRGKSVADAIAILTFTP
                     NKAAEIILKVLNSAVANAENNFGLDKANLVVSEAFANEGPTMKRFRPRAKGSASPINK
                     RTAHITVAVAEK"
     gene            complement(8806..9087)
                     /gene="rpsS"
                     /locus_tag="VQ543_001293"
     CDS             complement(8806..9087)
                     /gene="rpsS"
                     /locus_tag="VQ543_001293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000533767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S19"
                     /protein_id="HET2612013.1"
                     /translation="MGRSLKKGPFVDEHLMKKVEAQANDEKKKVIKTWSRRSTIFPSF
                     IGYTIAVYDGRKHVPVYIQEDMVGHKLGEFAPTRTYKGHAADDKKTRRK"
     gene            complement(9191..10024)
                     /gene="rplB"
                     /locus_tag="VQ543_001294"
     CDS             complement(9191..10024)
                     /gene="rplB"
                     /locus_tag="VQ543_001294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019790357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L2"
                     /protein_id="HET2612014.1"
                     /translation="MGIRVYKPTTNGRRNMTSLDFAEITTSTPEKSLLVALKSKAGRN
                     NNGRITVRHQGGGHKRFYRLVDFKRNKDNVEAVVKTIEYDPNRSANIALVHYTDGVKA
                     YIIAPKGLEVGQRIVSGPEADIKVGNALPLANIPVGTLIHNIELKPGRGGELVRAAGA
                     SAQVLGSEGKYVLVRLQSGEVRMILGTCRATVGVVGNEQHGLVNLGKAGRSRWKGIRP
                     TVRGSVMNPNDHPHGGGEGKAPVGRKAPSTPWGKPALGLKTRNKKAKSDKLIVRRRNE
                     K"
     gene            complement(10042..10338)
                     /locus_tag="VQ543_001295"
     CDS             complement(10042..10338)
                     /locus_tag="VQ543_001295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007518994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L23"
                     /protein_id="HET2612015.1"
                     /translation="MNLYDVIKKPVITESSMAQLEAGKYVFEVDTRAHKLLIKQAVEA
                     AFEGVKVANVNTINVKPKAKRVGRYTGFTNKTKKAIITLTADSKAIELFAAEAE"
     gene            complement(10338..10961)
                     /gene="rplD"
                     /locus_tag="VQ543_001296"
     CDS             complement(10338..10961)
                     /gene="rplD"
                     /locus_tag="VQ543_001296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L4"
                     /protein_id="HET2612016.1"
                     /translation="MANVTLFDQTGKEAGQVVLSDAVFGIEPNESVVFDVIISQRASL
                     RQGTHAVKNRSAVSGGGRKPWRQKGTGRARQGSIRSPQWRGGGVVFGPTPRSYGYKLP
                     QKVRRLALKSVYSEKVAENKFVAVDALSFTAPKTAEFAKVLAALSIDSKVLVILEEGN
                     EFAALSARNLPNVKVATATTASVLDIANSDKLLVTQAAISKIEEVLA"
     gene            complement(10986..11612)
                     /gene="rplC"
                     /locus_tag="VQ543_001297"
     CDS             complement(10986..11612)
                     /gene="rplC"
                     /locus_tag="VQ543_001297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3"
                     /protein_id="HET2612017.1"
                     /translation="MTKGILGKKVGMTQIFTEAGELIPVTVIEATPNVVLQVKTVETD
                     GYNAIQVGFDDKREVLSNKPAKGHVAKANTAPKRFIREFKNVEGLEVGAEITVETFAA
                     GDVVDVTGTSKGKGFQGVIKRHGQSRGPMAHGSRYHRRPGSMGPVAPNRVFKGKNLAG
                     RMGGDRVTIQNLEVVQVVPEKNVILIKGNVPGAKKSLITIKSAVKAGK"
     gene            complement(11828..12136)
                     /gene="rpsJ"
                     /locus_tag="VQ543_001298"
     CDS             complement(11828..12136)
                     /gene="rpsJ"
                     /locus_tag="VQ543_001298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S10"
                     /protein_id="HET2612018.1"
                     /translation="MANKKIRIRLKAYEHRTLDTAAAKIVESATRTGAQVAGPIPLPT
                     ERSLYTIIRATHKYKDSREQFEMRTHKRLIDIVNPTQKTVDALMKLDLPSGVNVEIKL
                     "
     gene            complement(12402..13019)
                     /locus_tag="VQ543_001299"
     CDS             complement(12402..13019)
                     /locus_tag="VQ543_001299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribulokinase"
                     /protein_id="HET2612019.1"
                     /translation="MKKKDLVDQLVSEIETGKVRTLGIYGHGASGKSTFAQELYQALD
                     STTVNLLETDPYITSGRYLVVPKDAPNQKVTASLPVAHELESLQRDILALQAGMDVLT
                     IEEPWKASEVLSGAKPILIVEGMSVGFLPKELFEKTICFYTDEETELKRRLARDTTVR
                     NRDASFILASHQMRREQYLRYYKETESKADILVDQSEDKFDVKRT"
     gene            complement(13016..13606)
                     /gene="nrdG"
                     /locus_tag="VQ543_001300"
     CDS             complement(13016..13606)
                     /gene="nrdG"
                     /locus_tag="VQ543_001300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001064213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase
                     activating protein"
                     /protein_id="HET2612020.1"
                     /translation="MNNPKPQEWKSEELSQGRIIDYKAFNFVDGEGVRNSLYVAGCMF
                     HCEGCYNVATWSFNAGIPYTAELEEQIMADLAQPYVQGLTLLGGEPFLNTGILLPLVK
                     RIRKELPDKDIWSWTGYTWEEMMLETPDKLELLSLIDILVDGRYDRTKRNLMLQFRGS
                     SNQRIIDVQKSLKSGQVVIWDKLNDGKEIYEQVKRE"
     gene            complement(13599..14105)
                     /locus_tag="VQ543_001301"
     CDS             complement(13599..14105)
                     /locus_tag="VQ543_001301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000423399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET2612021.1"
                     /translation="MELRRPRLADKKAVLDMMTEFEKSQSAHDGGFWDVEDFSYEEWL
                     EGNRNKEMGIWLPENRVPSIQFVLFGESGCALGFLNLRLRLNEGLLNYAGHIGYSIRP
                     SERGKGYAKETLRQGLQVAKEKNIKKALVTCSVNNPASRAVILANGGIFEDARNGVER
                     YWIEVANE"
     gene            complement(14149..14289)
                     /locus_tag="VQ543_001302"
     CDS             complement(14149..14289)
                     /locus_tag="VQ543_001302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000521630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2612022.1"
                     /translation="MGKYQLDDKGRAQVTRYHEKHSKGGAGKKERLLSFREQFLNKNK
                     KK"
     gene            complement(14301..16508)
                     /gene="nrdD"
                     /locus_tag="VQ543_001303"
     CDS             complement(14301..16508)
                     /gene="nrdD"
                     /locus_tag="VQ543_001303"
                     /EC_number="1.17.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004239081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase"
                     /protein_id="HET2612023.1"
                     /translation="MIALEEKITILPTLFVEKRDGRRVVFDVDKIDKALHKAADKVMD
                     VTPLVEKRLNDLTERIITEIHSRFPQGIKIYEIQNIVEHELLEAKEYALAEEYITYRT
                     QRDFERSKATDINFSIHKLLNKDQTVVNENANKDSDVFNTQRDLTAGIVGKSIGLQML
                     PKHVANAHQKGDIHYHDLDYSPYTPMTNCCLIDFKGMLENGFKIGNAEVESPKSIQTA
                     TAQISQIIANVASSQYGGCSADRIDEILAPYAEKNYQKHLKDAEEWVLPEKREDYAWK
                     KTQKDIYDAMQSLEYEINTLFTSNGQTPFTSLGFGLGTSRFEREIQKAILNIRIKGLG
                     SEHRTAIFPKLIFTLKRGLNLEEGTPNYDIKQLALECATKRMYPDVLSYDKIVDLTGS
                     FKVPMGCRSFLQGWKDENGVEVNSGRMNLGVVTVNLPRIALESEGDMNKFWEIFNERM
                     NIAEDALVYRVERTKEATPANAPILYQYGAFGHRLGKEESVDQLFKNCRATVSLGYIG
                     LYEVATVFFGNSWESNPDAKEFTLDIIHDMKRRVEEWSDQYGYHFSIYSTPSESLTDR
                     FCRLDIDKFGSIPDITDKEYYTNSFHYDVRKNPTPFEKLDFEKVYPEAGASGGFIHYC
                     EYPVLQQNPKALEAVWDYAYDRVGYLGTNTPIDRCYKCDFEGDFEPTERGFACPNCGN
                     SDPKTVDVVKRTCGYLGNPQARPMVNGRHKEIAARVKHMNGSTIKIAGHQVTN"
     gene            complement(16628..18166)
                     /locus_tag="VQ543_001304"
     CDS             complement(16628..18166)
                     /locus_tag="VQ543_001304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="damage-inducible protein CinA"
                     /protein_id="HET2612024.1"
                     /translation="MSVYGRVEEVHKENREPLEYQIEQESHHRESSRLPLVKILLWST
                     LVTGITLGVPLLLDLMSAQEVQDFYAGWALHQTGKIYSDYYGSQGLLYYLLTYVSQGG
                     FFFAIFEWLALVAGGFFLFRSADTLTEQGDQAGHLVTIFYMLVTGLAFGGGYATLLAL
                     PFLFAAFSLVAAYLSNPSHDKGFVRIGLALAGGFFFAPLSSLLFIAVVSLGLLVFNLG
                     HRRFAHGFYQFLAVALGFSLVFYPTAYYSAATGSFGDAISGIRYPIDSIRFDFTSKIL
                     ENMFFYGLLSLGLGFVVCIFLGLFQSKPFKLYVISVPASLVVILGLILLFFSQEPLHA
                     SYLMVVFPVFLLLLVTNIKSQQRGRSARRSRRETPVSLWSRFFKGNLYLLVFGFVYLL
                     SVPFLMKFVLYPVPYQERNRLADLVKEETNTEDAIYAWDDTATLYRKSERLSPSAILS
                     PLHYTATEENRNKLLNDLKEKQPKVIVVNDKVVVWSEVETLLKENYQQVKTDYSEFKV
                     YKIK"
     gene            complement(18203..18346)
                     /locus_tag="VQ543_001305"
     CDS             complement(18203..18346)
                     /locus_tag="VQ543_001305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000956126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2612025.1"
                     /translation="MLTKEEVNDMIEFKQTHLHRFREIETFVKLCKKSLKQPSQADNP
                     RTF"
     gene            complement(18424..19956)
                     /gene="cls"
                     /locus_tag="VQ543_001306"
     CDS             complement(18424..19956)
                     /gene="cls"
                     /locus_tag="VQ543_001306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000877342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HET2612026.1"
                     /translation="MKYRKFQLLMSKYGFSLSIMLLELCLVFGLFLYLGRMAPILWIT
                     VLILLSIITIISIVNRNTTPENKVTWLLVAFVPVFGPLLYLMFGERRLSKKEIKQLKK
                     LGSMHFQEANSQLLKEKLKESDKAAYGVIKSLLSMDTNADIYDQTASTFFPNGEAMWK
                     KMVEDLKKAEKFIFLEYYIIEEGLMWNRILDILEQKVAQGVEVKMLYDDIGCMATLTG
                     DYAHRLRQLGIEAHKFNKVIPRLTVAYNNRDHRKILIVDGQIAYTGGVNLADEYINHV
                     ERFGYWKDSGIRLDGLAVKALTRLFLTTWYINRGEISDFDQYHLENHSIPSDGLTIPY
                     GSGPKPIFRAQVGKKVYQSLINQATESVYITTPYLIIDYDLTETIKNAAMRGVDVRII
                     TPYIPDKKFIQLVTRGAYPDLLSAGVRIYEYSPGFIHSKQMLVDEDFAVVGTINLDYR
                     SLVHHYENAVLLYKTPSIREIARDFRNIFADSQEVYPHSIKTSWYQKLVKEIAQLFAP
                     IL"
     gene            complement(20102..20659)
                     /locus_tag="VQ543_001307"
     CDS             complement(20102..20659)
                     /locus_tag="VQ543_001307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001816192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipocalin/fatty acid-binding family protein"
                     /protein_id="HET2612027.1"
                     /translation="MTPLFELVILGELLVRENFSKLVAERKFIMKLKRFTLSLASLAS
                     FSLLVACSQRAQQVQQPVAQQQVQQPAQQPAQQNTNTANAGGNQNQAAPVQNQPVAQP
                     TDIDGTYTGQDDGDRITLVVTGTTGTWTELESDGDQKVKQVTFDSANQRMIIGDDVKI
                     YTVNGNQIVVDDMDRDPSDQIVLTK"
     gene            complement(20656..21906)
                     /locus_tag="VQ543_001308"
     CDS             complement(20656..21906)
                     /locus_tag="VQ543_001308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000464354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HET2612028.1"
                     /translation="MFEVEEWLHSRIGLNFRSGLGRIQQAVDLLGNPEQSYPIIHVTG
                     TNGKGSTIAFMRELFMGHGKKVATFTSPHIVSINDRICINGQPIADADFIRLADQVKE
                     MEKTLLQTPDQLSFFEMLTLVAFLYFREQEVDLVLLEVGIGGLLDTTNVVTGELAVIT
                     SIGLDHQETLGDSLEAIAEQKAGIFKAGKKAVIAKLPPEARLVCQKKAESLAVNLYQA
                     GQDFLMLNGDFSSSLLNFSQLNIGLEGVYQQENAALALQTFLLFMGEGKEAVDEQAVR
                     KALEQTHWAGRLERIRPQIYLDGAHNLPALTRLVEFIKEKEQEGYRPQILFGALKRKD
                     YQGMLGYLTEKLPQVELKVTGFDYQGALDERDVTGYDIVSSCREFISSFEERADAQDL
                     LFVTGSLYFISEVRGYLLDREQIN"
     gene            complement(22114..22419)
                     /locus_tag="VQ543_001309"
     CDS             complement(22114..22419)
                     /locus_tag="VQ543_001309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1292 domain-containing protein"
                     /protein_id="HET2612029.1"
                     /translation="MSHDHNHDHEERELITLVDEQGNETLFEILLTIDGKEEFGKNYV
                     LLVPVNAEEDEDGQVEIQAYSFIENEDGTEGELQPIPEDSEDEWNMIEEVFNSFMEE"
     gene            complement(22435..22854)
                     /gene="ruvX"
                     /locus_tag="VQ543_001310"
     CDS             complement(22435..22854)
                     /gene="ruvX"
                     /locus_tag="VQ543_001310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002939356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RuvX"
                     /protein_id="HET2612030.1"
                     /translation="MRIMGLDVGSKTVGVAISDPLGFTAQGLEIIQINEEQGQFGFDR
                     VKELVDTYKVERFVVGLPKNMNNTSGPRVEASQAYGAKLEEFFGLPLDYQDERLTTVA
                     AERMLIEQADISRNKRKKVIDKLAAQLILQNYLDRKF"
     gene            complement(22858..23124)
                     /locus_tag="VQ543_001311"
     CDS             complement(22858..23124)
                     /locus_tag="VQ543_001311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IreB family regulatory phosphoprotein"
                     /protein_id="HET2612031.1"
                     /translation="MGFTEETVRFKLDDSNKKEISETLTDVYASLNDKGYNPINQIVG
                     YVLSGDPAYVPRYNNARNQIRKYERDEIVEELVRYYLKGQGVDL"
     gene            complement(23211..23780)
                     /locus_tag="VQ543_001312"
     CDS             complement(23211..23780)
                     /locus_tag="VQ543_001312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HET2612032.1"
                     /translation="MKKIVLVSLAFLFVLVGCGQKKETGPATKTEKDTLQSALPVIEN
                     AEKNTVVTKTLVLPKSDDGSQQTQTITYKDKTFLSLTIQQKRPVSDELKTYIDQHGVE
                     ETQKALLEAEEKDKSIIEARKLAGFKLETKLLSATELQTTTSFDFQVLDVKKASQLEH
                     LKNIGLENLLKNEPSKYISDRLANGATEQ"
     gene            complement(23846..24244)
                     /gene="spx"
                     /locus_tag="VQ543_001313"
     CDS             complement(23846..24244)
                     /gene="spx"
                     /locus_tag="VQ543_001313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017768833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator Spx"
                     /protein_id="HET2612033.1"
                     /translation="MIKIYTVSSCTSCKKAKTWLNAHQLSYKEQNLGKEGITREELLD
                     ILTKTDNGIASIVSSKNRYAKALGVDIEDLSVNEVLNLIMETPRILKSPILVDEKRLQ
                     VGYKEDDIRAFLPRSVRNVENAEARLRAAL"
BASE COUNT         6740 a         5398 c         4560 g         7629 t
ORIGIN      
        1 tttttcaata tctgagaaga catcattgat atcttgatta ccttcgatgt catgaaccaa
       61 acctttggca cggtagtgag caatgattgg ttctccttga gcaatattaa catccaaacg
      121 acgttttact gtctcaggct tatcatcttc acgttggtag taatcttctt ctttatagtc
      181 aactggtggg ttaaagacct tgtggaaagt ttctccagtt acgcggtgga tgatacggcc
      241 actcaaacgt tccaagaggc tgtcagggtt cacttcaata ttgataatac cttctagttc
      301 aatgccaagt tcagccaatg ttttgtccaa ggcatgagct tgttcaattg tacgtgggta
      361 accatccaat aagaatcctg tttctttaat atcatcttgt gaaaggcgtt cttttacgat
      421 tccatttgta acttcgtcag gaaccaattc acccttgtca atatatgact tagcaagaac
      481 acccatttca gtttgatttg ccattgcagc gcggaacata tcacctgttg agatatgtgc
      541 aacatggaat tgttctacga tttttgctgc ttgagttccc ttacctgcac caggtaagcc
      601 cataatcaaa agattcatga tttgatctcc ttattttatt tttaaataga agcaaaaagt
      661 cttttcaccc ctatttaaaa acaaaataga agaggggaga tccaactctt acaaatgtca
      721 gagtttaaac ctccactccc tcagtattta ctgattcagt aaatactttt attctgttct
      781 gtccatgaaa ccaacatact tacgtttcaa taggtaacct tccaattgct tgattccttc
      841 gatacctgta gagataatga tcaagagact tgttccacca aaggcaacaa catcagaaag
      901 accaaataca tctttagctg caatcggtaa aatggaaatc acaccaagga agagggaacc
      961 aacagttgca agacgacgaa gaagtttaga catatattct tctgtacctt taccaggacg
     1021 aactccatgg atataggcac cactcttttg taggctctct gctgcttttt caggattaat
     1081 ctgtacaaac gtatagaaga atgtaaagag aataatcaac aaagcataca tggcaatacc
     1141 agttggagaa gtagttgcca acatctcttg tgctaccctt acccaagccc aatcatgacc
     1201 tgtggcactc aaaaactgaa gaatagccgc aggcgctgca gtaatcgaac tggcaaagat
     1261 aacagggata actccagcag ggtttacctt taacggaagg taagagctag atggagcacc
     1321 ttgtgcaacc ttagtatatt ggattggaat tttgtattct gcttgttgaa cataagttgt
     1381 aaagtaaata atcaacaata cagtaataat caaaatgatt acgaaaatga tagatgaagt
     1441 gatacggcta cttgggacgt tcacaaagta gtccacatag atgccctgaa tcatctctgg
     1501 aattgaggaa acaatcccgg caaagataat catggaaaca ccgtttccgt atcccttatc
     1561 tgtaatttgc tcacccaacc aagtgacaat catactacca gctgttaaga tgataccaat
     1621 cgtcagaaaa acttgtggag ttaaagcagt tttaatcaat tgagctccag ccaaggtatt
     1681 aaaaccagct gtaatcccga tagattgcac aaaagcgaga actagagcaa tataacgagt
     1741 agcttgattc aattttcttc gacctacttc cccttgttta ccccactcta caaacttggg
     1801 taaaatatcc atttgcaaga gttggacaac aatagaagcg gtgatatagg gactaactcc
     1861 tagggcaaaa atcgaaaagt tttttagggc attccccgac accaagctca acatgtttaa
     1921 gaaggataat ccacttaaag cattcaagct attggcattc acaccaggaa ctgtaatgct
     1981 agttccgata cgaaagacca aaacgataaa aattgtaaat aaaatttttg atcgaacctg
     2041 cttgacttta agagcttctc ttaataattt aaaaaacata ggtcacctct cttagatgac
     2101 ttctactgaa ccacctttag cagtgatagc ttcttcagct gatttagaga atttagctgc
     2161 tttcacagtc aatttcttag tcaactcacc gttaccaaga attttaatac ctgacttttc
     2221 agctttaaca attcctgctt cgataagaac aactggagtt acttcagcac catcttcaaa
     2281 gacgttcaat tggtcaaggt tcacaattgc gtattcttta gcgttgatgt tagtgaatcc
     2341 acgttttgga agacgacgga acaatggagt ttgtccacct tcaaaaccaa ggcgaactcc
     2401 gccaccgcta cgagcttttt gacctttttg accacgacca gatgttttac cgttacctga
     2461 tgaagtacca cgaccaacgc ggttacgtac tttacgagaa ccttctgcag gtttcaattc
     2521 atgaagtttc atttttattt tctcctcttt tgtaaaatgc tagcgccgat aagggagaaa
     2581 aggttgtctc ccccatcaac tcgcctatac gatgtcatca tagatgacta tatctagttt
     2641 taggggatgg tacagtgcac atcccctaaa acttcattag tttacttctt caactgttac
     2701 taagtgagat actgctgtaa tcataccacg gatagcagcg ttatcttctt taataacaga
     2761 gctgttcaat ttgccaagtc caagtgctac aacagtttta cgttgtgatg gaatgcgtcc
     2821 gattggagac ttagtcaaag taattttaat ttgagccatt ttatcccctt tcttatgcca
     2881 aatcagaaac tgaaatacca cgaagggcag caatttcttc agcgcgtttc aattgtttca
     2941 aaccttcaac agttgcacga acaatgttga ttggagtgtt agaaccaagt gatttagatg
     3001 taatatctgc cacacctgcc aattccacaa cggcacgaac tgcaccacca gcggcaactc
     3061 cagaaccttc tacagcaggt ttcaacaata ctttagctcc accgaattct gaaagaactt
     3121 cgtgtgggat tgttgttcca accataggaa cttcgatcaa gtttttctta gcatcatcta
     3181 ctgctttacg gattgcttct ggaacttctt gagctttacc agtaccaaat cctacgcgac
     3241 cattgtggtc accaacaaca acaagagctg cgaaacgaag acgacgtcca cctttaacaa
     3301 cttttgtaac acggttgaca gcaactacgc gttcttctaa ttcaactgca ttgtctttaa
     3361 atgccatttt ctagtgtcct cctattagaa tttcaatccg ttttcacgag ctgcatcagc
     3421 caaagctttc acacgtccgt gatatagata tccaccgcgg tcgaacacca cttctgaaat
     3481 acctttagcg tttgcacgtt ctgcaacgag tttaccgaca gcaacggctt gttcagtttt
     3541 agttcctttt gaaacttctt tatcaagagt tgaagcactt gcgagcgtta cacccgctac
     3601 gtcatcaatc acttgagcgt agatgcctgt attagaacgg aatacgttca aacgtgggcg
     3661 atcagcagtt ccagagagtt ttccgcgaac gcgacggtgg cgtttttggc ggagtttgtt
     3721 tttatctggt tttgaaatca cagttttcac ctctttagtt ttaaatcgtg tgctatgcac
     3781 aaagttggaa aataggttgg tggttgatga tcaaccactc aacattattt acctgtttta
     3841 ccttctttac ggcgaacgaa ttcaccaacg taacggatac ctttaccttt atatggttct
     3901 ggtgaacgaa ggctacgtac gtaagcagct gtttgaccaa ctacttcttt tgaaattccg
     3961 ctaacaacga ttgttgttgg gtttggaagt tcaaaagtaa ttccttctgg agcttcaact
     4021 tcgtctggat gagatttacc aacagccaaa acaagtttag atccttgaag ctgtgcacgg
     4081 taaccaaccc cacgcatttc aagttctttc ttgaatcctt ctgatacacc aacaaccatg
     4141 ttgttcaaaa gggcacgagt agttccgtgg atagttttca tttcttttga atcgtttgga
     4201 cggtgaagag ttatttcagt accttccaca cggatttcaa tatcttttga gaactcacga
     4261 gtaagttctc ctttaggtcc ttttacagtt acaacgttgt cattgttagc gagttcaaca
     4321 ccagcaggca acacgataac tttattacca atacgtgaca tgtttatttt ctcctgttaa
     4381 attgtcaggc cagaacggcc agttttcacg gggttcagat acttatttag ttcaagagct
     4441 gaactgaaca cgctctaaga actgtgcaaa atagataagt tggcttgttt gtaaacaaac
     4501 ttctccaact tcctaatttt gctttgttct ttacgagctt tgtatcttga ttttaccaaa
     4561 cgtaagcgat aacctcacca ccaacattct tttggcgtgc ttctttatca gtaagcaaac
     4621 cttcagaagt tgaaaggatg gcaattccaa gtccgttaag aacttttgga aggtcttcac
     4681 gttttttgta gacacgaagt cctggtttag aaacacgttt caagttagtg ataactttct
     4741 caccatttgg tccgtattta agaaatacac ggatgacgcc ttgtttgtca tcttcaatga
     4801 tttcaacgtt ttttacaaaa ccttcgcgtt taaggatttc agcaatccct tttttgatgt
     4861 ttgatgcagg tacttcaagt acttcgtgtt tagcttggtt agcattacga atacgagtta
     4921 ggaagtctgc gattgggtca gtcataacca ttttgttttt ctcctcttac tagtagtttg
     4981 caagttgcac ttgctagtta atacatgata caaagagcgt aacagcacga gcaaaaatag
     5041 acaatttaat gcagaagcaa tgctccaaag caaattggtc ttttttgcca aagctgtagc
     5101 tcgtgttcaa attggcaagc ccaattgaac ccgggctaaa ctctgtgtga aaaagataaa
     5161 ctttcctaga aactttagtt tcttcgtcaa gtttcctatt tttacttgga gttttgacgc
     5221 tcttgatatc ttaaattacc aagatgcttt tgttacacca ggaatttgac ctttatgcgc
     5281 aagttcgcga aaagcgatac gactcagacc aaatttgcgg taaactgaat gtgggcgccc
     5341 cgtaactcta caacgattat gtaaacgagt cggtgaggcg ttgcgaggta atttagataa
     5401 accttcgtag tcccctgccg cctttaatgc agcacgtttt tcagcataac ggtcaacaat
     5461 tttttggcgt ttagcctctc tagctaccat tgatttttta gccattagat ttacctccta
     5521 tattattttg caaaaggcat tccaaggcct gtaagcaatg cacgtgactc ttcgtcagtg
     5581 ttagcagttg ttacgataac gatgtcaaga ccacgagttt tgtcaacgtc atcgaagttg
     5641 atttctggga agattaattg ttctttcaca ccaagtgtgt agttcccgcg tccatcaaat
     5701 gattttgttg gaacaccgtg gaagtcacgt acacgtggaa gtgaaactga taccaattta
     5761 tccaagaatt cgtacatacg ttcaccacga agggtaactt ttgcaccgat cgcaacacct
     5821 tcacgaagac ggaagccggc gattgatttt ttagctttag tgataagtgg tttttgacct
     5881 gagataagtg ccaattcttc agcagctttt tcaaggcttt tagcgtttga tacagcttca
     5941 ccaacaccca tgttcaaaac aatcttatct actttaggca cagccatcac tgatgagtag
     6001 ttgaattgtt ctgtcaaagc aggaactact tcattaagat atttttcttt taaacgattt
     6061 gccattatac ttctcctttc cttcgtgatt aatcaagcac ttcgcctgat tttttgttgt
     6121 agcgaacttt tttaccgtct acaaatttgt aaccaacacg accagctaca ccatttttgt
     6181 ccaaaacttg aacgtttgat acgtggatag ctgcttcttt ctcgatgata ccaccttgag
     6241 gaagctcgtt agttggacgt tggtgtttct taacaatgtt aacaccttca acgataactt
     6301 tgtttacttt tggaagggca gtaaggacaa cagcttctgt tcccttatct ttaccagcga
     6361 ttacgcgaac tttgtcgcct ttttttacaa acattaggtt tctccttgat ttttcttacg
     6421 cccataaggg caccctagct tgaagctagg ggactagttt gttcctaaaa attaaagtac
     6481 ttctggagca agtgacacga tcttcatgaa gccaccttca cgcaattcac gtgcaactgg
     6541 gccaaagata cgtgttccgc gaggagtttt gtcttcacgg atgataactg ctgcgttttc
     6601 gtcaaatttg atgtatgaac catcagcacg acgagcacct gatttagtac gaacgataac
     6661 tgctttaaca acgtcacctt ttttaaccgc accaccagga gtagcttgtt ttacagatgc
     6721 cacgataaca tcaccgatgt ttgcaaattt acgtcctgaa ccaccaagaa ctttgatagt
     6781 caagatttcg cgagcaccgc tgttgtctgc gactttcaaa cgagtttctg tttgaatcat
     6841 ttcagttttc tcctttcagg tttgattaga tgatgaccgc ttcttcaaca acttctacaa
     6901 gacggaaacg ttttgtagct gaaagcgggc gagtttccat gatacgtacg atatcgcctt
     6961 ctttggcaac attgttttca tcatgagctt tgtatttttt agagtagtta atacgtttac
     7021 catagactgg gtggttacgt tttgtttcaa ctacaactgt gattgtcttg tccattttgt
     7081 cagatacaac acgtccaaca agaactttac gattattgcg ttccattgaa atttctcctt
     7141 ccctagtcta ttatttcgct tcagattgaa ctgttttgat acgagcgatt tgttttttaa
     7201 cttctttcaa gcgagctgtt tgttccaatt gaccagtagc agcttggaaa cgaagttcaa
     7261 acaattcttt tttcaattcg ttttcgcgct tcgcgagttc ttcttgagaa agaccacgaa
     7321 gttctttaac aaattctttt acttcattaa gtttcatgcc ttctccttat tctgcttcac
     7381 gttttacgaa tttacattta actggcaatt tgtggctagc aagtcgaagc gcttcacgtg
     7441 caatctcttc agatacacca gcgatttcga acatcacttt accacgttta actggtgcta
     7501 cccaaccttc aggtgcccct ttaccagatc ccatacgcac accgatagct ttagcagtgt
     7561 atgatttgtg tgggaagatt ttaatccaaa ctttaccacc acgtttcatg taacgagtca
     7621 tggcgatacg agcagcttcg atttggcggt tagtgatcca gtggctagtt gtagcttgaa
     7681 gaccgtattc accgaatgct acttcttttc caccttttgc ttcaccgcgc atttttccac
     7741 ggaactcacg acggtgttta acacgtttag gtactaacat tggttattta cctcctttag
     7801 tgtttttacg agctggaaga acttcaccac ggtagatcca tactttaaca ccaagtttac
     7861 cgtatgtagt atctgcttct tcccaagcgt aatcgatatc tgcacgaagt gtgtgaagcg
     7921 gaacagttcc ttcagagtat ccttcagcac gggcgatatc tgcaccgttc aaacgacctg
     7981 atacttgagt tttgattcct ttagctccag cacgcattgc acgttggatt gcttgttttt
     8041 gtgcacgacg gaaagcaaca cgttgctcca attgacgagc aattccttca cctacaaggt
     8101 gagcatccaa atcaggttgt ttgatttcga tgatgttgat gtgtacttgt tttccagtca
     8161 atttgttaag ttttgcacgg agtgcatcaa cgttagcacc acctttaccg ataaccatac
     8221 ctggtttagc agtgtgaagt gaaacgttaa ctttgtttac tgcgcgttcg atttcaatag
     8281 ttgaaactgc tgcgtcagca agttcttttt gaacgaattt acggattgca agatcttcat
     8341 gaaggtaatc cgcgtattct ttttcagcat accatttggc atcccaatca cggatgatgc
     8401 cgacacgcat accaattgga tgtacttttt gacccacgat tttacctcct tatttttctg
     8461 caacagctac agtgatgtga gctgtacgtt tgttgattgg tgaagctgaa cctttcgcac
     8521 gtggacggaa acgtttcata gttggtcctt cgtttgcgaa tgcttcagat actaccaaat
     8581 tagctttatc caaaccaaag ttgttttcag cgttagctac agctgagttc aaaactttca
     8641 agatgatttc agcagctttg tttggagtga atgtcaagat tgcgattgca tcggctacgc
     8701 ttttaccacg gatgttatca agaacaagac gtgatttacg aggtgaaaca cgtactgtac
     8761 gagccattgc tttagctgaa gtaatttctg ccatttatgt tctccttatt ttctacgtgt
     8821 tttcttgtcg tctgcagcgt gacctttgta agtacgagtt ggtgcaaatt caccaagttt
     8881 gtggcctacc atgtcttctt ggatgtaaac aggtacgtgt ttacgtccgt cataaactgc
     8941 aatagtgtaa ccaatgaaac ttgggaagat cgttgaacga cgtgaccaag ttttaataac
     9001 ttttttcttt tcgtcgttag cttgagcttc aacttttttc atcaaatgct catcgacgaa
     9061 aggtcctttt ttaagactgc gtcccatttt tatattttct cctttaaatg ttgtaccaca
     9121 gcggcttgca ctcctatgga gcgctaccga gctggcggat ttactagttg cttaagcgac
     9181 tagtttaata ttatttctcg ttgcgacgac gaacgataag tttgtcagat ttcgctttct
     9241 tgttacgagt tttaagacca agagcaggtt tgccccatgg agtagatggt gctttacgac
     9301 caactggtgc tttaccttca ccaccaccgt gtgggtgatc gttagggttc attacagaac
     9361 cacgaactgt tgggcggata cctttccaac ggctacgtcc tgctttacca aggtttacaa
     9421 gtccatgttg ttcgtttccg acaacaccaa ctgtagcacg gcaagttcca agaatcatac
     9481 gaacttcacc tgattgaaga cgaacaagaa catatttacc ttcagaaccc aatacttgag
     9541 cagatgcacc agcagcacgt accaattcac caccacgacc tggtttcaac tcgatgttgt
     9601 gaatcaaagt accaactggg atgttagcaa gtggaagagc gtttccgact ttgatatctg
     9661 cttctggacc tgaaacgata cgttgaccta cttcaagacc ttttggagcg atgatgtatg
     9721 ctttcacacc gtcagtgtag tgtacaagag cgatgtttgc agaacggttt ggatcgtact
     9781 cgattgtttt aacaactgct tcaacgttgt ctttattacg tttgaagtca accaaacggt
     9841 aaaaacgttt gtgtccacca ccttggtgac gaactgtgat acgaccgttg ttgttacgac
     9901 cagccttgct cttcaatgca acaagcaatg atttttcagg agtgcttgtt gtgatttcag
     9961 cgaaatccaa agaagtcata ttacggcgac cgtttgttgt tggtttataa acacgaattc
    10021 ccacgatatt tcctccttag attattcagc ttcagcagca aacaactcga ttgctttaga
    10081 atcagctgta agtgtgatga tagctttttt agttttgtta gtaaaaccag tgtaacgtcc
    10141 aacacgttta gcttttggtt ttacgttgat tgtgttaaca ttggcaactt taacaccttc
    10201 gaaagcagct tcaacagctt gcttgatcaa aagtttgtgt gcacgagtgt caacttcaaa
    10261 tacatatttt cctgcttcaa gttgagccat tgagctttca gtgatgacag gttttttgat
    10321 aacatcatac aaattcatta tgcaagaacc tcctcgattt tagagatagc tgcttgtgtg
    10381 acaagaagtt tgtcgctatt tgcgatgtca agaacacttg cagttgtagc agttgcaact
    10441 ttcacgtttg gaaggttacg agctgaaaga gctgcgaatt catttccttc ttcaaggata
    10501 acaagaactt tagaatcgat gctcaatgct gcaagaactt ttgcaaattc agcagttttt
    10561 ggagctgtaa atgaaagagc gtctacagct acgaatttgt tttcagcaac tttttcagag
    10621 taaactgatt taagagctag gcgacgaact ttttgtggaa gtttgtagcc gtatgaacgt
    10681 ggagttggtc cgaagacaac accaccacca cgccattgtg gtgagcggat agaaccttga
    10741 cgagcacgtc cagttccttt ttgacgccat ggtttgcgtc caccacctga tactgcagag
    10801 cggtttttaa cagcgtgtgt tccttgacga aggcttgcgc gttggctgat gattacatca
    10861 aacacaactg attcatttgg ttcgatacca aatactgcat cgctaagaac aacttggcca
    10921 gcttctttac cagtttggtc aaataatgtt acgtttgcca ttgtgactga tttccccttt
    10981 ctttattatt taccagcttt aactgctgat ttgatagtga taagagattt cttagcacct
    11041 ggtacgttac ctttgataag gataacgttc ttttctggaa caacttgtac aacttcaagg
    11101 ttttgaattg ttacgcggtc gccacccata cgccctgcaa ggtttttacc tttgaatacg
    11161 cggttaggtg caacaggtcc catagaacct ggacgacggt ggtaacgaga accgtgagcc
    11221 attggtccac gtgattgtcc gtggcgtttg ataacacctt ggaaaccttt acctttagaa
    11281 gtaccagtta cgtcaacaac gtctccagct gcgaatgttt caactgtaat ttcagcacca
    11341 acttccaagc cttcaacgtt tttgaattca cgaatgaagc gcttaggagc cgtgttagct
    11401 ttcgctacat gtcctttagc aggtttgttg ctcaatactt cgcgtttgtc atcgaaacca
    11461 acttggatag cgttgtatcc gtctgtttca acagttttaa cttgaagaac aacgtttgga
    11521 gttgcttcaa taactgttac agggatcaat tcgccagctt cagtgaagat ttgagtcatt
    11581 cccacttttt tccctaagat tccttttgtc atgagaaaat agttcctttt ctatattttt
    11641 attcaaaaag tttttaacga gcgtttttta tgctcaagtc taagatacaa agggcgtcaa
    11701 actcaacgtg aaaataggaa actgacacag tgtctagcag acgcgaggaa gtttatcttt
    11761 ttcacaccga gtttagcccg tgttcaatta gattgaaaca ccagcctctg ctcttttata
    11821 ttttagatta aagtttgatt tctacgttta caccacttgg aagatccaat ttcatcaagg
    11881 catcaactgt tttttgagtt gggttaacga tatcgatcaa acgtttgtgt gtacgcattt
    11941 caaattgttc gcgagagtct ttgtatttgt gagtcgcacg aatgattgtg tagaggctac
    12001 gttcagttgg aagtgggatt ggacccgcaa cttgtgcacc tgtacgagta gctgattcta
    12061 cgatttttgc agccgctgtg tcaagcgtac ggtgttcgta agctttcaaa cggatacgga
    12121 tttttttgtt tgccatcttt ttctcctttt cgtctattta agataatagg ctagctccac
    12181 aagaaaaccg acgcggtgtt gcgtggcaat gcaaccgagc gtgtcgcaac ctcttgcatc
    12241 aaaactaagg ctgtaattta cagcaccata atagaataac acaaatcccc tgcgattgca
    12301 agggatttgt taggtttttt cgttttttgg ggatgaaact gttttcctac tttttctttc
    12361 taaaattagg gattttcttc tatatttctt ctatacataa gttaagtcct cttgacatca
    12421 aatttatctt ctgattggtc cactaagata tccgccttag actcagtttc tttatagtat
    12481 cgcagatact gctcccgtct catctgatgg ctagccaata taaaggatgc atcgcgattt
    12541 ctcacagtcg tatctctagc aaggcgtcgc tttaattcgg tctcctcatc cgtgtagaaa
    12601 cagatggttt tttcaaagag ttccttgggt agaaagccaa cagacatccc ttcgacaatc
    12661 aaaattggtt tggctccaga caagacctca ctagccttcc aaggttcttc aattgtcaag
    12721 acatccatac ccgcctgcaa ggcaaggata tctctctgca aactctccag ttcatgcgcc
    12781 actggcagac tggctgtcac cttttgattc ggcgcgtcct tgggtactac caaatagcgt
    12841 ccggaggtga tatagggatc tgtttctagc aaatttactg tagtagaatc taaagcttgg
    12901 tacaattcct gtgcaaaggt tgatttacct gaagctccat gaccgtatat tcccagtgtc
    12961 ctgactttcc ccgtctcgat ctctgagact agttggtcta ctaagtcttt tttcttcatt
    13021 ctctcttcac ctgttcatag atttcttttc cgtcattgag cttgtcccaa atcactactt
    13081 gcccactttt gagcgatttt tgcacatcga taattcgttg gttagacgaa cctcgaaact
    13141 ggagcataag atttctctta gttcgatcat atcttccatc gacaagaatg tcaatcagtg
    13201 acaagagttc cagtttatct ggagtttcca acatcatttc ttcccaagtg tagcccgtcc
    13261 aggaccagat gtccttgtct ggcaattcct tccgaatccg cttaacaagt ggcaagagaa
    13321 tcccagtatt aagaaaaggc tcccctccta gtaaggttaa cccctgaaca taaggctggg
    13381 caagatctgc cataatctgt tcttccaact cagctgtata gggaatgcct gcattgaagg
    13441 accaggtcgc tacattataa cacccctcgc agtgaaacat acagcctgct acatagagag
    13501 agttacgcac gccttcgcca tcaacaaagt taaaggcctt gtagtcaatg atacgacctt
    13561 gactaagttc ctcgcttttc cattcttgtg gttttggatt attcattcgc tacctctatc
    13621 caataacgct cgactccatt gcgagcatcc tcaaatattc caccatttgc tagaatgact
    13681 gctctgctag caggattatt cacgctacag gtcaccagag ctttcttgat gttcttttcc
    13741 ttagcaactt gcaagccctg acggagagtc tcttttgcat aacccttgcc tctttcagat
    13801 ggacggatgg agtagccaat gtggccagca taattcagta acccctcatt cagtctcaat
    13861 cgcagattca aaaatcctag agcacaacct gattcaccaa acaatacgaa ctgtatcgat
    13921 ggaacgcgat tttcaggtag ccatattccc atttctttat tacggttacc ttctagccac
    13981 tcctcgtaag aaaaatcctc aacatcccaa aatcctccat catgggctga ttggctcttt
    14041 tcaaactctg tcatcatatc taaaacagct ttcttatccg ctaatcttgg tctgcgtaat
    14101 tccatcctta cctcccacta tgagaaaagc gagagctggc tctcactttt attttttctt
    14161 gttcttgttt aaaaattgtt ctctgaagct aagcaagcgt tctttcttac cagctccacc
    14221 tttagagtgt ttctcgtgat aacgggtcac ttgtgcgcgc cccttatcgt ctagttgata
    14281 ttttcccatt tcatttcttt ctaatttgtt acttgatgcc cagctatttt aatcgttgaa
    14341 ccattcatat gtttgacacg cgcagcgatt tccttgtgac gcccgttgac catcggtctt
    14401 gcttgaggat tacctaggta gccacaagtt cgcttcacca catctactgt tttagggtcg
    14461 ctattgccac agtttggaca agcaaaccct ctctcagttg gttcaaaatc cccttcaaag
    14521 tcacacttgt agcaacggtc aatcggagta ttggtgccta gatagcctac acggtcataa
    14581 gcataatccc agacagcttc caaggccttt ggattttgct gaaggactgg atactcacaa
    14641 taatggatga aaccacctga cgcacctgct tctggataga ctttctcaaa gtccaatttt
    14701 tcaaacggtg ttggattttt acgaacatcg tagtggaaag agttggtgta gtattccttg
    14761 tctgtgatat caggaataga gccaaacttg tctatatcta gtcggcagaa acggtctgtc
    14821 agactttcgg atggtgttga gtagatagag aaatggtagc catattggtc tgaccactct
    14881 tctacacggc gtttcatatc gtgaatgatg tctagcgtga attccttagc atctggatta
    14941 ctttcccagc tgttaccaaa gaaaactgtc gctacttcat acaagccgat atagcccagc
    15001 gaaacggtcg cacgacaatt cttaaagagc tggtcaacac tttcttcttt acctagacga
    15061 tggccaaaag caccgtactg ataaaggata ggagcattcg ctggtgtcgc ctctttagtg
    15121 cgttcgacac ggtaaacaag agcatcttct gcgatattca ttcgctcgtt gaagatttcc
    15181 cagaacttat tcatatcacc ttcagactca agagcaatac gaggcagatt aaccgtcaca
    15241 acacccagat tcatgcgacc tgaattgact tctacaccat tttcatcctt ccatccttgg
    15301 aggaaagaac ggcaacccat aggcaccttg aaggatcctg tcaagtcaac aatcttatcg
    15361 taagataaaa catctggata catccgtttg gttgcacact caagagccaa ctgcttgatg
    15421 tcgtagttgg gagttccttc ctctaaatta aggcctcttt tcagagtgaa aataagttta
    15481 ggaaagatag ccgtacggtg ttctgaacca agacccttga tgcgaatgtt taaaatagct
    15541 ttttgaattt ctcgttcaaa acgactggtt cccagaccaa aacctagcga agtaaaaggt
    15601 gtttgtccat ttgaagtgaa gagagtattg atttcatact caagagattg catggcatcg
    15661 tagatgtcct tttgcgtttt cttccaagcg taatcttccc gtttttcagg caatacccac
    15721 tcttctgcat ctttgagatg tttttgatag ttcttctctg cataaggcgc caaaatttca
    15781 tcgatacggt cagctgaaca gccaccgtac tggctagaag caacgttggc aatgatttga
    15841 gaaatctgtg ctgtcgcagt ctggatagac ttgggactct ctacctctgc atttccaatc
    15901 ttaaaaccat tttccaacat acccttaaaa tcaatcaaac agcagttggt cataggggta
    15961 tagggactgt agtccaaatc gtgatagtgg atatccccct tttggtgggc attggctacg
    16021 tgcttaggaa gcatttgcag tccgattgat ttcccaacaa tccctgctgt caaatcacgc
    16081 tgagtgttaa agacatcact gtctttatta gcattttcat tgacaactgt ctggtctttg
    16141 ttgagaagtt tatgaatact aaagttgata tccgtcgctt ttgagcgctc aaaatccctc
    16201 tgtgtccgat aagtaatata ctcctcagcc agcgcatatt ctttggcttc aaggagttca
    16261 tgttctacga tattttgaat ttcgtaaatc ttaattccct gtggaaagcg actatgaatt
    16321 tctgtaataa ttctctcagt cagatcattg aggcgttttt caaccagggg tgtcacatcc
    16381 ataaccttgt cagctgcctt gtggagagcc ttgtcaatct tgtccacatc aaatacaaca
    16441 cgtctcccat ctcgtttctc gacgaagaga gttggcaaaa ttgtaatttt ttcttctagt
    16501 gcaatcatat gcatgctctt ttctaaaatg ttctttctaa aaagtattat accactctaa
    16561 aaagaaaaat caatatcttg tgttaaaaat cctaaaattt ttaaaaatac acaagatatt
    16621 gatttggtta tttaatttta tagactttaa actctgagta atcagtcttt acttgttggt
    16681 aattttcttt taaaagtgtt tccacttcag accagactac caccttgtca tttaccacaa
    16741 tcaccttagg ttgtttttct ttcaagtcat taagtaactt attacgattt tcctcagttg
    16801 ctgtatagtg caacggggac aaaatcgccg atggcgacaa gcgctcactc ttacgataaa
    16861 gagtcgcagt atcatcccat gcatagatag catcttccgt atttgtctcc tcttttacca
    16921 aatcagcaag acgattacgt tcttgataag gtactggata aaggacaaac ttcatcaaaa
    16981 aaggaacaga caaaagatag acaaacccaa aaactagcag atatagattt cctttgaaga
    17041 aacgactcca taggctaact ggcgtttctc ttcggcttct tctagcacta cgccccctct
    17101 gttgactctt gatattggtt accaataaaa gtaggaaaac agggaagacg accatcaaat
    17161 aagaagcgtg cagaggctct tgtgaaaaga aaagtaaaat caaacctaaa attaccacaa
    17221 gacttgcagg aaccgaaatg acgtatagtt taaagggttt ggattgaaag agacctaaaa
    17281 agatacaaac cacaaatccc aaaccaaggg acaacaagcc ataaaaaaac atattctcta
    17341 aaattttaga agtaaaatca aagcgaatac tgtcaatagg ataacgaata ccactaatcg
    17401 catccccaaa acttcctgtt gcagcactat agtaggcagt tggataaaag acaagtgaaa
    17461 aacctaaagc cactgcaaga aactgataaa acccatgcgc aaagcgtcta tgcccaaggt
    17521 taaagaccaa caagcctaaa ctcactacag caataaacag gagtgatgat aagggagcaa
    17581 agaaaaatcc gcctgccaaa gctaacccaa tccgtacaaa tcccttatca tggcttggat
    17641 tgcttaggta agccgcaact aaactaaagg ctgcgaataa gaaaggaagc gctaaaagag
    17701 tcgcatagcc tccaccaaaa gcaagacctg taactagcat gtaaaaaata gtcaccagat
    17761 gtccagcttg gtctccttgc tctgtcaagg tgtccgctga tctaaaaagg aaaaatcctc
    17821 ctgctaccaa ggctaaccac tcaaagatgg caaagaaaaa tccgccctga ctcacgtaag
    17881 tcagcaaata ataaagcaaa ccttgacttc cataatagtc gctgtaaatc ttccctgtct
    17941 gatgaagcgc ccaacctgca taaaaatcct gcacttcttg tgcactcatt aagtcgagta
    18001 atagcggtac tcctagagtt atccccgtta caagcgtact ccatagtaaa attttcacca
    18061 aaggaagacg acttgattca cgatgatgcg attcttgctc gatttggtat tctagaggtt
    18121 cacgattctc cttatgaact tcttctactc taccatacac actcatatcg tttctcctgt
    18181 tcaatttatc tgtcttagta tatcaaaaag tcctaggatt gtcagcttgc gatggctgtt
    18241 tgagtgattt tttgcatagt ttcacaaagg tttcaatttc ccgaaagcgg tgtaaatgtg
    18301 tctgtttgaa ctcaatcata tcattcactt cttccttagt tagcatgaat tcccctcctc
    18361 tttctttcta ttcgtaaaag acaagaaaaa taggtcgggt ttgtatccta agttctagat
    18421 ttcttataag ataggggcga atagctgggc gatttctttt acaagctttt gataccagct
    18481 cgttttgata gaatgaggat agacttcctg agaatctgca aatatatttc gaaaatctcg
    18541 ggcgatttcc cttatagaag gagttttata gagtaagact gcattttcat aatggtgtac
    18601 caagctccgg tagtcgagat tgattgtccc caccaccgca aaatcttcgt ctaccaacat
    18661 ctgcttacta tgaataaaac ctggactata ctcataaatc cgaacaccag cagaaagaag
    18721 gtcgggataa gctcctctcg tgactaactg aatgaacttc ttatctggta tgtaaggggt
    18781 gataattcga acatcgaccc ctctcatagc tgcatttttg attgtctctg ttaaatcata
    18841 atctataatc aaataaggtg tcgtaatata gaccgattcc gttgcttgat tgattaaact
    18901 ctgataaact tttttcccta cctgcgctcg aaaaattggc ttgggtccac ttccgtatgg
    18961 aatggttaaa ccgtcactcg ggatagaatg attttctaaa tgatattgat caaaatcact
    19021 aatttctcct cgattaatgt accaagtggt caaaaataag cgtgtcaggg cttttactgc
    19081 tagtccgtct aagcgaattc cactatcctt ccaataacca aatctctcga cgtggttaat
    19141 gtactcatct gccagattga ccccaccagt ataggctatc tgaccatcaa caatcaatat
    19201 ttttctatga tctctgttat tataagccac tgtcaaacga ggaataactt tattgaattt
    19261 atgggcctcg atgcccagct gacgaagtcg atgtgcataa tctcctgtta aagtagccat
    19321 acagccgata tcatcataga gcatcttaac ctctacaccc tgagctacct tttgctctag
    19381 tatatctagt atgcgattcc acatcaaacc ttcttctata atgtaatatt ccaagaaaat
    19441 aaatttctca gcctttttaa gatcttctac catctttttc cacatagctt ctccgttagg
    19501 aaaaaatgta gaggcagttt gatcatagat gtcagcattg gtatccatac tcaataagga
    19561 cttgatgact ccataagctg ccttgtcact ttcttttaat ttctctttta gtagctggct
    19621 atttgcttct tggaaatgca tagagcctag cttcttcagt tgtttgattt cttttttgga
    19681 caatcgcctt tcaccaaaca tcagatagag taagggacca aatactggca caaaggctac
    19741 taacaaccag gttaccttat tctcaggagt cgtattacgg ttgactatcg aaatgattgt
    19801 gatgatactc agtagaatga ggacagtaat ccataaaatg ggagccatgc gtcctaaata
    19861 aagaaagaga ccaaaaacaa gacaaagttc aagtagcata atcgaaagac taaagccata
    19921 cttggacatc aataattgaa atttcctata tttcatatcc cctccttgat agtttgaatg
    19981 ctaaaaacaa gtaattgata ctagtataac gcaggtattc ggtagaaggc aagtatttat
    20041 gattattttc taggtaaaag taaaaaggct gaaaaatcca gccctttcta cttgcatagt
    20101 cttatttagt taaaacgatt tggtccgatg ggtctctatc catatcatct acgacgattt
    20161 gattaccgtt tacagtgtaa attttgacat catcgccaat aatcatgcgt tgatttgctg
    20221 aatcaaatgt aacctgtttg actttctgat ccccgtcaga ttcgagctca gtccatgtac
    20281 cagtcgttcc agttaccact aaagtgatac ggtctccgtc atcctgacca gtataagtcc
    20341 catcaatatc ggtcggttga gcaacaggtt ggttttgtac tggagccgct tgattttggt
    20401 tacctcctgc atttgcagta ttggtattct gttgagcagg ttgttgagca ggctgttgga
    20461 cctgctgctg agcaacaggc tgttgaacct gttgagctct ttgtgaacaa gctactaaga
    20521 gactaaaact tgctagagaa gcaagagaaa gtgtgaatct ttttaatttc atgatgaatt
    20581 tcctttctgc taccaattta gagaaatttt ctctaaccag caattcccct agtataacaa
    20641 gttcaaacaa gggggtcaat ttatctgctc acggtccagc aggtagcccc gtacttctga
    20701 gataaaatag agagaccctg taacgaacag caagtcttga gcgtctgccc tttcttcgaa
    20761 actgctgata aattctcggc aagaagaaac tatatcgtaa cctgtcacat ccctttcgtc
    20821 caaagccccc tgatagtcaa agccggtcac cttgagttcc acctgaggca atttttcagt
    20881 caggtaacct aacatccctt gataatcctt ccgtttcaag gctccaaaaa ggatttgagg
    20941 tcgatagcct tcctgctctt tttctttgat aaactcaacc aagcgagtca aggcagggag
    21001 gttatgagca ccatccaagt aaatctgtgg gcgaatacgc tccaagcgac cagcccaatg
    21061 ggtctgttcc aaggcctttc ttacagcctg ttcatcaaca gcttcctttc cttctcccat
    21121 aaaaagaaga aaagtttgca acgccaaggc tgcattctcc tgctgataga ctccttctaa
    21181 gcctatgttc agctgtgaaa aatttagtaa agagcttgaa aaatcaccat tcagcattaa
    21241 aaaatcttga cctgcctgat aaaggttaac agctaaagat tcggcttttt tctgacagac
    21301 aagcctagct tctggaggca atttcgcaat cactgccttc ttaccagcct tgaaaatacc
    21361 agctttctgc tctgcaattg cttctagact atcacccaag gtttcttgat ggtcaagccc
    21421 aatggaggtg atgacagcaa gctctccagt taccacattg gtcgtgtcaa gtaagccacc
    21481 aattcccact tctaataaaa ccaaatccac ctcttgctcc ctaaaataaa gaaaagcaac
    21541 caaggtcagc atttcaaaaa aggacaactg gtcaggagtt tgcagaagcg ttttctccat
    21601 ctccttgacc tgatcagcca aacggataaa gtctgcgtct gctataggtt gcccattaat
    21661 gcagattcgg tcattgatag agacgatatg aggggaggta aaggtcgcaa cttttttgcc
    21721 atgccccata aataattccc tcataaaagc aatggtagat cctttcccat tagtccctgt
    21781 tacgtggata atagggtaag actgctcagg atttcctaac aaatccaccg cttgctgtat
    21841 tcggcccaaa cctgatcgaa aattcaaacc aatccgacta tgaagccatt cttctacttc
    21901 aaacatacac atctccttga caaaagtcca atcaattatc gcattaaagt atggttacta
    21961 ataaaaacaa ggccaggatt ttcgtcccga cctcttacct ggttagctaa taactagcca
    22021 ctatgaatgt gaatatgggc taaaaacatc cactagatgt tccaactctt ccccatttct
    22081 gggagttggg ctgatacagt ctcccagact gtatcactcc tccataaagc tgttgaagac
    22141 ttcttcaatc atgttccatt cgtcttctga gtcttctggg attggttgca attcgccttc
    22201 tgttccatct tcattttcaa tgaatgagta agcttggatt tcaacttgtc cgtcttcgtc
    22261 ttcttctgcg ttaactggta ctagaagaac atagttttta ccaaattctt cttttccatc
    22321 aattgtcaaa aggatttcaa acaaggtttc atttccttgc tcatctacta gtgtgattag
    22381 ttcacgttct tcgtggtcgt ggttatgatc gtgtgacata gcctctcctt tatattaaaa
    22441 ttttctatct aaataatttt gtaaaatcag ctgagctgct aacttatcaa tgactttctt
    22501 gcgcttattg cgactgatat ctgcttgttc aatcaacatg cgctcagcag ccactgttgt
    22561 caagcgttca tcctgatagt ctaatggtaa accaaaaaac tcttctagct ttgctccgta
    22621 ggcttgacta gcttctacgc gcggtccact tgtattgttc atgtttttag gcaagcccac
    22681 tacaaatcgt tccaccttgt aagtatcaac caattcctta acgcggtcaa aaccaaattg
    22741 gccttgttct tcatttatct ggatgatttc aagcccttga gctgtaaaac caagcggatc
    22801 gctaatcgcc acccctaccg tttttgaacc gacgtccaat cccataattc tcataggtta
    22861 tagatcgact ccttgtcctt tgaggtagta gcgaaccaat tcctcaacga tttcatcacg
    22921 ctcatactta cggatttgat ttcgtgcatt attataacga ggaacgtagg cagggtctcc
    22981 actcaatacg taacctacga tttggttaat tgggttgtaa cccttatcgt tcaacgaagc
    23041 ataaacatct gtcaaagttt cgctaatttc ttttttattg gaatcgtcca atttaaaacg
    23101 tactgtttct tcagtaaatc ccattctaac accctctttc cttagaatag taccattata
    23161 gcataattcc ttaccttcta caattcaggc agtctattta tttggatttt ctattgttct
    23221 gtcgcgccat ttgccaatct atctgaaata tatttgcttg gttcattttt caaaagattt
    23281 tccaaaccaa tattcttcag atgttccaac tgggaagcct tcttgacatc cagaacttga
    23341 aaatcaaaac tagtcgttgt ttgaagttcc gttgcgctca atagttttgt ttcaagtttg
    23401 aaacctgcca atttacgagc ttcaatgata gacttatcct tctcctccgc ttcaagaaga
    23461 gctttttgag tttcctccac tccatgttgg tcaatataag tcttcaactc atcagagact
    23521 ggacgttttt gttggatagt tagactcaaa aaagtcttgt ccttgtatgt aatggtttgt
    23581 gtctgctggc taccatcatc tgacttgggc aagaccaaag tcttagttac aactgtattc
    23641 ttctcagcat tttcaataac tggcaatgcc gactgaagcg tatctttttc tgtttttgta
    23701 gctggtccag tttctttttt ctgtccgcaa ccaaccagga caaaaaggaa agctagacta
    23761 acaagaacta tttttttcat ttctttcttc tttctttttg aaattaaaat agaataagac
    23821 tgggaagtgc tcccagcctt gatgtttata gagctgcacg caaacgtgct tctgcatttt
    23881 ctacattacg gacagagcgt ggtaggaagg cacgaatatc gtcttccttg tagccaactt
    23941 gcaggcgttt ttcatctaca aggattgggc tctttaaaat tctcggtgtt tccataatca
    24001 gattgagaac ttcattgaca ctcaaatctt caatatccac tccaagggct ttggcatagc
    24061 gatttttaga cgaaacgatg ctggctattc cgttatctgt tttggttaga atatccagta
    24121 attcttctct cgtaattcct tctttaccaa ggttttgttc tttataactt aactggtggg
    24181 cattgagcca ggtttttgct tttttacagc tagtacaact tgagactgta taaattttaa
    24241 tcatgtacct acccctttcg ctacatgtta ctatcagttt agtctattat accataaaaa
    24301 acatccgact tgcgacctat ttttaat
//
LOCUS       DAVBEO010000032        24252 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 009
            SAMEA1678075-rid20185393.denovo.032, whole genome shotgun sequence.
ACCESSION   DAVBEO010000032 DAVBEO010000000
VERSION     DAVBEO010000032.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678075
            Sequence Read Archive: ERR226392
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 24252)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24252)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980207.1
            Genome Coverage       :: 150x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:50:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 72 of 147
            Pseudo Genes (incomplete)         :: 72 of 147
            Pseudo Genes (internal stop)      :: 42 of 147
            Pseudo Genes (multiple problems)  :: 32 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24252
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678075-rid20185393.denovo.032"
                     /strain="KS 009"
                     /db_xref="taxon:1313"
     gene            <1..335
                     /locus_tag="VQ543_001314"
     CDS             <1..335
                     /locus_tag="VQ543_001314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET2612034.1"
                     /translation="GLTNGELIAPMTYEEMMTSDFFEAWFQKFLLPTLTTPSAIIMDN
                     ARFHRMGKLELLCEEFGHKLLPLPPYSPEYNPIEKTWAHIKKHLKKVLPSCCNTFYEA
                     LLSCSCFN"
     gene            complement(542..2800)
                     /locus_tag="VQ543_001315"
     CDS             complement(542..2800)
                     /locus_tag="VQ543_001315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HET2612035.1"
                     /translation="MLCQNCKINDSTIHLYTNLNGKQKQIDLCQNCYKIIKTDPNNSL
                     FKGMTDLNNRDFDPFGDFFNDLNNFRPSSNTPPIPPTQSGGGYGGNGGYGSQNRGSAQ
                     TPPPSQEKGLLEEFGINVTEIARRGDIDPVIGRDDEIIRVIEILNRRTKNNPVLIGEP
                     GVGKTAVVEGLAQKIVDGDVPHKLQGKQVIRLDVVSLVQGTGIRGQFEERMQKLMEEI
                     RKREDIILFIDEIHEIVGAGSASDGNMDAGNILKPALARGELQLVGATTLNEYRIIEK
                     DAALERRMQPVKVDEPTVDETITILKGIQKKYEDYHHVQYTDAAIEAAATLSNRYIQD
                     RFLPDKAIDLLDEAGSKMNLTLNFVDPKVIDQRLIEAENLKSQATREEDFEKAAYFRD
                     QIAKYKEMQKKKITDQDTPIISEKTIEHIIEQKTNIPVGDLKEKEQSQLIHLAEDLKS
                     HVIGQDDAVDKIAKAIRRNRVGLGTPNRPIGSFLFVGPTGVGKTELSKQLAIELFGSA
                     DSMIRFDMSEYMEKHSVAKLVGAPPGYVGYDEAGQLTEKVRHNPYSLILLDEVEKAHP
                     DVMHMFLQVLDDGRLTDGQGRTVSFKDAIIIMTSNAGTGKTEASVGFGAAREGRTNSV
                     LGELGNFFSPEFMNRFDGIIEFKALSKDNLLQIVELMLADVNKRLSSNNIRLDVTDKV
                     KEKLVDLGYDPKMGARPLRRTIQDYIEDTITDYYLENPSEKDLKAVMTSKGNIQIKSA
                     KKAEVKSSEKEK"
     gene            complement(3029..3259)
                     /locus_tag="VQ543_001316"
     CDS             complement(3029..3259)
                     /locus_tag="VQ543_001316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005592360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YkuJ family protein"
                     /protein_id="HET2612036.1"
                     /translation="MESHLVRIINRLEAMANDGGNLKRNFEREGVVVAEVAYSHDEEN
                     GPIFTLRDVEDRETYTFDSIDLIAMEIYELLY"
     gene            3449..4132
                     /locus_tag="VQ543_001317"
     CDS             3449..4132
                     /locus_tag="VQ543_001317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001011621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HET2612037.1"
                     /translation="MNFSFLPKYLPYFNYGAVVTILISICVIFLGTILGVVLAFGQRS
                     KFKPLVWLANLYVWIFRGTPMMVQIMIAFALMHINAPTIQIGILGVDFSRLIPGILII
                     SMNSGAYVSEIVRAGINAVPKGQLEAAYSLGIRPKNAMRYVILPQAVKNILPALGNEF
                     ITIIKDSSLLSAIGVMELWNGATTVSTTTYLPLTPLLFAAFYYLIMTSILTVALKAFE
                     KHMGQGDKK"
     gene            4132..4866
                     /locus_tag="VQ543_001318"
     CDS             4132..4866
                     /locus_tag="VQ543_001318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000140960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HET2612038.1"
                     /translation="MTETLIKIENLHKSFGKNEVLKGINLEIKRGEVVVIIGPSGSGK
                     STLLRSMNLLEEATKGKVIFEGVDITDKKNDLFAMREKMGMVFQQFNLFPNMTVMENI
                     TLSPIKTKGESREVAEKRAQELLEKVGLPDKADAYPQSLSGGQQQRIAIARGLAMEPD
                     VLLFDEPTSALDPEMVGEVLAVMQDIAKSGMTMVIVTHEMGFAREVADRVIFMADGVV
                     VEDGTPEQIFEQTQEQRTKDFLSKVL"
     gene            5020..5877
                     /locus_tag="VQ543_001319"
     CDS             5020..5877
                     /locus_tag="VQ543_001319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000192112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional methylenetetrahydrofolate
                     dehydrogenase/methenyltetrahydrofolate cyclohydrolase"
                     /protein_id="HET2612039.1"
                     /translation="MTQIIDGKALAAKLQGQLAEKTAKLKEETALVPGLVVILVGDNP
                     ASQVYVRNKERSALAAGYRSEVVRVPETITQEELLDLIAKYNQDPAWHGILVQLPLPK
                     HIDEEAVLLAIDPEKDVDGFHPLNMGRLWSGHPVMIPSTPAGIMEMFHEYGIDLEGKN
                     AVVIGRSNIVGKPMAQLLLAKNATVTLTHSRTHNLAKVAAKADILVVAIGRAKFVTAD
                     FVKPGAVVIDVGMNRDENGKLCGDVDYEAVAPLASHITPVPGGVGPMTITMLMEQTYQ
                     AALRTLDRK"
     gene            6019..6891
                     /locus_tag="VQ543_001320"
     CDS             6019..6891
                     /locus_tag="VQ543_001320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000864675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-hydrate dehydratase"
                     /protein_id="HET2612040.1"
                     /translation="MKVINQTLLEKVIIERSRSSHKGDYGRLLLLGGTYPYGGAIIMA
                     ALAAVKSGAGLMTVGTDRENIPALHSHLPEPMAFSLQDQQLLKEQLEKAEVILLGPGL
                     GDNAFGEDLVKQVFAGLKQNQILIVDGGALTILARTSLSFPSSQLILTPHQKEWEKLS
                     GITIEKQKEDATASVLTSFPQGTILVEKGPATRIWEVGQSDYYQLQVGGPYQATGGMG
                     DTLAGMIAGFVGQFRQASLYERVAVATHLHSAIAQELSQENYVVLPTEISRYLPKIMK
                     IICQQERVSKDKLV"
     gene            7173..7856
                     /gene="rpiA"
                     /locus_tag="VQ543_001321"
     CDS             7173..7856
                     /gene="rpiA"
                     /locus_tag="VQ543_001321"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000429260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-5-phosphate isomerase RpiA"
                     /protein_id="HET2612041.1"
                     /translation="MENLKKMAGIKAAEFVSDGMVVGLGTGSTAYYFVEEIGRRIKEE
                     GLQITAVTTSSVTTKQAEGLNIPLKSIDQVDFVDVTVDGADEVDSQFNGIKGGGGALL
                     MEKVVATPSKEYIWVVDESKLVEKLGAFKLPVEVVQYGAEQVFRHFERAGYKPSFREK
                     DGQRFVTDMQNFIIDLALDVIENPIAFGQELDHVVGVVEHGLFNQMVDKVIVAGRDGV
                     QISTSKKGK"
     gene            7870..9081
                     /locus_tag="VQ543_001322"
     CDS             7870..9081
                     /locus_tag="VQ543_001322"
                     /EC_number="5.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopentomutase"
                     /protein_id="HET2612042.1"
                     /translation="MSKFNRIHLVVLDSVGIGAAPDANNFVNAGVPDGASDTLGHISK
                     TVGLNVPNMAKIGLGNIPRETPLKTVAAESNPTGYATKLEEVSLGKDTMTGHWEIMGL
                     NITEPFDTFWNGFPEEILTKIEEFSGRKVIREANKPYSGTAVIDDFGPRQMETGELII
                     YTSADPVLQIAAHEDIIPLDELYRICEYARSITLERPALLGRIIARPYVGEPGNFTRT
                     ANRRDLAVSPFSPTVLDKLNEAGIDTYAVGKINDIFNGAGINHDMGHNKSNSHGIDTL
                     LKTMGLAEFEKGFSFTNLVDFDALYGHRRNAHGYRDCLHEFDERLPEIIAAMRENDLL
                     LITADHGNDPTYAGTDHTREYIPLLAYSPAFKGNGLIPVGHFADISATVADNFGVETA
                     MIGESFLDKLV"
     gene            9083..9625
                     /locus_tag="VQ543_001323"
     CDS             9083..9625
                     /locus_tag="VQ543_001323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1697 domain-containing protein"
                     /protein_id="HET2612043.1"
                     /translation="MTRYALLVRGINVGGKNKVVMAELRQELTNLGLEKVESYINSGN
                     IFFTSIDSKAQLVEKLETFFAVHYPFIQSFSLLSLEDFEAELENLPAWWSRDLARKDF
                     LFYTEGLDVDQVIATVESLELKDEVLYFGKLGIFWGKFSEESYSKTAYHKYLLKVPFY
                     RHITIRNAKTFDKIGQMLKK"
     gene            9641..10450
                     /locus_tag="VQ543_001324"
     CDS             9641..10450
                     /locus_tag="VQ543_001324"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HET2612044.1"
                     /translation="MTFLNKIHETATFLKEKGIAAPEFGLILGSGLGELAEEIENPVV
                     VDYAEIPNWGRSTVVGHAGKLVYGELAGRKVLALQGRFHFYEGNPLEVVTFPVRVMKV
                     LGCEGVIVTNAAGGIGFGPGTLMAISDHINMTGQNPLMGENLDDFGPRFPDMSRAYTP
                     EYRATAHEVAKKLNIKLDEGVYIGVTGPTYETPAEIRSYKTLGADAVGMSTVPEVIVA
                     AHSGLKVLGISCITNFAAGFQEELNHEEVVEVTERVKGDFKGLLKAILAEL"
     gene            10926..11906
                     /locus_tag="VQ543_001325"
                     /pseudo
     CDS             10926..11906
                     /locus_tag="VQ543_001325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855254.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="discoidin domain-containing protein"
     gene            11931..12443
                     /locus_tag="VQ543_001326"
     CDS             11931..12443
                     /locus_tag="VQ543_001326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001275913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin"
                     /protein_id="HET2612045.1"
                     /translation="MSAQITINHKKARYVRIELEGYNALSLAEVEVFRFIATNAETAT
                     QVSKPVQPISQTPVKDKTLTIQHSGAYIARYSITWEEVPVDKDGNQVVRSHSWEGNGR
                     NQTAGFVLNLPIKENMRNLRVKIEKKTGLLWNRWQTIYENRPISAQPHRKITHWGTTL
                     NSKVSDDDVL"
     gene            13090..13800
                     /gene="deoD"
                     /locus_tag="VQ543_001327"
     CDS             13090..13800
                     /gene="deoD"
                     /locus_tag="VQ543_001327"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HET2612046.1"
                     /translation="MSIHIAAQQGEIADKILLPGDPLRAKFIAENFLDDAVCFNEVRN
                     MFGYTGTYKGHCVSVMGTGMGMPSISIYARELIVDYGVKKLIRVGTAGSLNEEVHVRE
                     LVLAQAAATNSNIVRNDWPQYDFPQIASFDLLDKAYHIAKKLGMTTHVGNVLSSDVFY
                     SNYFEKNIELGKWGVKAVEMEAAALYYLAAQYHVDALAIMTISDSLVNPDEDTTAEER
                     QNTFTDMMKVGLETLIAE"
     gene            complement(13823..14347)
                     /locus_tag="VQ543_001328"
     CDS             complement(13823..14347)
                     /locus_tag="VQ543_001328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000684222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topology modulation protein"
                     /protein_id="HET2612047.1"
                     /translation="MKIAIIGYSGSGKSTIAEKLSNYYSIPKLHMDTLQFQPGWQDSD
                     CEWMLTEIKNFLTKHKAWVIDGNYSWCYYQERMQEADQIIFLNFSPLTCLFRAFKRYL
                     KYRGKVRESMAADCPERFEWEFIRWILWDGRSKTQKENYQKLCQEYSHKVTILRNQRE
                     LDQFLDKKRKSYNS"
     gene            complement(14400..14636)
                     /locus_tag="VQ543_001329"
     CDS             complement(14400..14636)
                     /locus_tag="VQ543_001329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001274003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S20"
                     /protein_id="HET2612048.1"
                     /translation="MANIKSAIKRAELNVKQNEKNSAQKSAMRTAIKAFEANPSEELF
                     RAASSAIDKAETKGLIHKNKASRDKARLSAKLAK"
     gene            complement(14704..15624)
                     /locus_tag="VQ543_001330"
     CDS             complement(14704..15624)
                     /locus_tag="VQ543_001330"
                     /EC_number="2.7.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pantothenate kinase"
                     /protein_id="HET2612049.1"
                     /translation="MTNEFLHFEKISRQTWQSLHRKTTPPLTEEELESIKSFNDQISL
                     QDVTDIYLPLAHLIQIYKRTKEDLAFSKGIFLQRESKSQPFIIGVSGSVAVGKSTTSR
                     LLQILLSRTFTDATVELVTTDGFLYPNQTLIEQGILNRKGFPESYDMEALLNFLDRIK
                     NGQDVDIPVYSHEVYDIVPEKKQSVKAADFVIVEGINVFQNPQNDRLYITDFFDFSIY
                     VDAGVDDIESWYLDRFLKMLSLAQNDPDSYYYRFTQMPIGEVESFAHQVWISINLTNL
                     QNYIEPTRNRAEVILHKSKNHEIDEIYLKK"
     gene            15814..16218
                     /locus_tag="VQ543_001331"
     CDS             15814..16218
                     /locus_tag="VQ543_001331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2612050.1"
                     /translation="MKILKRYILELCFILSFALPFIKGTNADNGRCFVETYYGFTFLM
                     EHAIVTAVFIYSFLIAFLLKKRWAKWIAAGSYCFLVLWIATEGYFFRMSLEDLIRLWT
                     SLEILTQTYQLGFYLNILLGILLIIKYFKVKQ"
     gene            16434..17015
                     /locus_tag="VQ543_001332"
     CDS             16434..17015
                     /locus_tag="VQ543_001332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000289981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HET2612051.1"
                     /translation="MYYAENPDAAHDIHELRVDLLGQKMTFLTDAGVFSKKMVDFGSQ
                     LLLKCLDVNQGETVLDVGCGYGPLGLSLVKVYGVQATMVDINTRALDLARRNAEKNNA
                     KATIFQSNIYEQVEGHFDHVISNPPIRAGKQVVHEIIEKSKDFLETGGDLTIVIQKKQ
                     GAPSAKSKMEDVFGNCEILKKDKGYYILRSVKE"
     gene            17012..18289
                     /locus_tag="VQ543_001333"
     CDS             17012..18289
                     /locus_tag="VQ543_001333"
                     /EC_number="2.4.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001202959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine-nucleoside phosphorylase"
                     /protein_id="HET2612052.1"
                     /translation="MRAVDLIQKKRDGQELTSSEIEWLVEGYVSGTVPDYQMSAFAMA
                     VYFKGMTTREISDLTMNMVKTGQEFDLSAIDGVKVDKHSTGGVGDKVTLILAPLVASF
                     GVPVAKMSGRGLGHTGGTIDKLESIRGYQVERSQEDFIRQVQDIGVSVIGQSDQLVKA
                     DKLLYALRDVTATVDTIPLIASSVMSKKIAAGADAILLDVTVGEGAFMKTVDEARELA
                     QTMVDLGKVVGRKTVAVITDMSQPLGRAIGNRLEILEALEILQGQGRQDITHFICELA
                     QIMLGLANVNKTVEEVHQHLENGQALAKFEEMVQAQGGDLEDLYRPVNVAHVVEIPAQ
                     ETGVISALPAMDFGLYAMRLGAGRAVKSDALDYETGIVFEKKIGDSVQKGEIVAKVYT
                     NEKIPPQLVTDFQKCVKISDEVKKIREIVEIIS"
     gene            18307..18969
                     /gene="deoC"
                     /locus_tag="VQ543_001334"
     CDS             18307..18969
                     /gene="deoC"
                     /locus_tag="VQ543_001334"
                     /EC_number="4.1.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000773666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribose-phosphate aldolase"
                     /protein_id="HET2612053.1"
                     /translation="MKLNKYIDHTLLKQDAKKKQIDSLLSEAREYDFASVCVNPTWVE
                     HAKKGLEGTDVKVCTVVGFPLGATTSAVKAFETKEAIQNGADEIDMVINVGALKSGNL
                     ALVESDIRAVVEASGDKLVKVIIEACLLTDQEKIVVCQLAQKAGADFVKTSTGFSTGG
                     ATIADVTLMRETVGSDMGVKAAGGARSYADALAFVEAGATRIGTSAGVAILKGELADG
                     DY"
     gene            18956..19345
                     /locus_tag="VQ543_001335"
     CDS             18956..19345
                     /locus_tag="VQ543_001335"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HET2612054.1"
                     /translation="MATTELIELAIETSKHAYVPYSHFPIGAVLVAKDGSVYTGVNIE
                     NASYPLTNCGERTAIFKAISEGQREFSELIVYGQTEKPISPCGACRQVMAEFFEQDLK
                     VTLVAKDKSTVEMTVGELLPYSFTDLN"
     gene            19435..20487
                     /locus_tag="VQ543_001336"
     CDS             19435..20487
                     /locus_tag="VQ543_001336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family protein"
                     /protein_id="HET2612055.1"
                     /translation="MNKKQWLGLGLVAVAAVGLAACGNRSSRNAASSSDVKTKAAIVT
                     DTGGVDDKSFNQSAWEGLQAWGKEHNLSKDNGFTYFQSTSEADYANNLQQAAGSYNLI
                     FGVGFALNNAVKDAAKEHTDLNYVLIDDVIKDQKNVASVTFADNESGYLAGVAAAKTT
                     KTKQVGFVGGIESEVISRFEAGFKAGVASVDPSIKVQVDYAGSFGDAAKGKTIAAAQY
                     AAGADIVYQVAGGTGAGVFAEAKSLNESRPENEKVWVIGVDRDQEAEGKYTSKDGKES
                     NFVLVSTLKQVGTTVKDISNKAEKGEFPGGQVIVYSLKDKGVDLAVTNLSEEGKKAVE
                     DAKAKILDGSVKVPEK"
     gene            20631..22166
                     /locus_tag="VQ543_001337"
     CDS             20631..22166
                     /locus_tag="VQ543_001337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000929819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2612056.1"
                     /translation="MAHENVIEMRDITKVFGGFVANDKINLHLRKGEIHALLGENGAG
                     KSTLMNMLAGLLEPTSGEIAVNGQVVNLDSPSKAASLGIGMVHQHFMLVEAFTVAENI
                     ILGSELTKNGVLDIAGASKEIKALSERYGLAVDPSAKVADISVGAQQRVEILKTLYRG
                     ADILIFDEPTAVLTPSEIDELMAIMKNLVKEGKSIILITHKLDEIRAVSDRVTVIRRG
                     KSIETVEIAGATNADLAEMMVGRSVSFKTEKQASKPKEVVLSIKDLVVNENRGVPAVK
                     NLSLDVRAGEIVGIAGIDGNGQSELIQAITGLRKVESGSIELKGDSIVGLHPRQITEL
                     SVGHVPEDRHRDGLILEMMISENIALQTYYKEPHSKNGILNYSNITSYAKKLMEEFDV
                     RAASELVPAAALSGGNQQKAIIAREIDRDPDLLIVSQPTRGLDVGAIEYIHKRLIEER
                     DNGKAVLVVSFELDEILNVSDRIAVIHDGKIQGIVSPETTNKQELGVLMAGGNLGKEK
                     SDV"
     gene            22159..23217
                     /locus_tag="VQ543_001338"
     CDS             22159..23217
                     /locus_tag="VQ543_001338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET2612057.1"
                     /translation="MSKKLQQISVPLISVFLGILLGAIVMWIFGYDAIWGYEELFYTA
                     FGSLRGIGEIFRAMGPLVLIGLGFAVASRAGFFNVGLPGQALAGWILSGWFALSHPDM
                     PRPLMILATIVIALIAGGIVGAIPGILRAYLGTSEVIVTIMMNYIVLYVGNAFIHAFP
                     KDFMQSTDSTIRVGANATYQTPWLAELTGNSRMNIGIFFAIIAVAVIWFMLKKTTLGF
                     EIRAVGLNPHASEYAGISAKRTIILSMIISGALAGLGGAVEGLGTFQNVYVQGSSLAI
                     GFNGMAVSLLAANSPIGILFAAFLFGVLQVGAPGMNAAQVPSELVSIVTASIIFFVSV
                     HYLIERFVKPKKQVKGGK"
     gene            23220..24176
                     /locus_tag="VQ543_001339"
     CDS             23220..24176
                     /locus_tag="VQ543_001339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET2612058.1"
                     /translation="MSIITLLPLLVSSMLIYSAPLIFTSIGGVFSERGGVVNVGLEGI
                     MVMGAFSGVVFNLEFAEQFGAATPWLSLLVAGLVGSVFSIIHAAATVHFRADHVVSGT
                     VLNLMAPALAVFLVKVLYNKGQTDNLSQTFGRFDFPVLANIPVIGDIFFKSTSLLGYL
                     AIAFSFLAWFILFKTQFGLRLRSVGEHPQAADTLGINVYKMRYLGIIISGFLGGIGGA
                     IYAQSISVNFSVTTIVGPGFIALAAMIFGKWNPIGAMLSSLFFGLSQSLAVIGSQLPF
                     LQGVPAVYLQIAPYVLTILVLAAFFGKAVAPKADGINYIKSK"
BASE COUNT         7049 a         4388 c         5513 g         7302 t
ORIGIN      
        1 caggtctaac aaatggtgag ttaatcgctc caatgactta cgaagagatg atgacgagcg
       61 acttttttga agcatggttt cagaagtttc tcttaccaac attaaccaca ccatcggcta
      121 ttattatgga taatgcaaga ttccatagaa tggggaagct agaactttta tgcgaagagt
      181 ttgggcataa acttttacct cttcctccct actcacctga gtacaatcct attgagaaaa
      241 catgggctca tatcaaaaag cacctcaaaa aggtattacc aagttgttgc aatacctttt
      301 acgaggctct tttgtcctgc tcttgtttca attgactata gcagattgaa ataagatgag
      361 aacaaatcga ttgggaaagt aaaattaatt tctataaatg ttttagcaat tgtttcgtac
      421 tatttcagat tcagtctact atatatcata atggacaaag ggcaagctgt caagaaatta
      481 cagttatttt agtaaaaaaa gaagcagaaa aatttaattt tctactcctt ttctatagga
      541 tttatttttc tttttcagaa cttttaactt cagctttttt ggcagattta atctgaatgt
      601 ttcccttgct agtcataact gctttgagat ctttttcgct tggattttca aggtagtagt
      661 cagtgattgt gtcctcaata tagtcttgaa tagtccgacg aagtgggcgt gctcccattt
      721 ttggatcata acctaggtca accaactttt ccttgacctt gtcagttaca tccaaacgaa
      781 tgttgttgct agagaggcgc ttgttaacat ctgctagcat gagctcgaca atctgaagga
      841 ggttatcctt gctgagagcc ttaaattcga taatgccatc aaaacggttc ataaactctg
      901 ggctaaagaa gttaccgagt tcaccgagga cagaattggt acgtccttct ctagcagcac
      961 caaatccaac gctagcttcg gtctttcctg tacctgcatt tgaggtcatg ataatgatgg
     1021 catccttgaa gctaacggtg cgtccttgcc cgtctgtcaa acgaccatcg tccaagactt
     1081 gaagaaacat gtgcataaca tctgggtgag ctttttccac ttcatcgaga aggatgagag
     1141 aatatggatt gtggcgaact ttttcagtta attgaccagc ctcatcatag ccaacataac
     1201 ctggaggagc gccgaccaac ttagccacac tatgtttttc catgtattca ctcatatcaa
     1261 agcgaatcat actatcagca gaaccaaaaa gttcgatagc cagttgtttg gaaagttctg
     1321 tcttaccgac accagttggc ccaacgaaga ggaagcttcc gattgggcgg ttaggggtac
     1381 caagtccgac acgattacgg cgaatagcct tggcaatctt atcgactgca tcatcttggc
     1441 caataacatg agacttgaga tcttcggcta gatggatgag ttgagattgt tctttctctt
     1501 tcaaatcacc aacagggata ttggttttct gctcgataat gtgctcaata gttttctcgc
     1561 tgatgatagg agtatcctgg tctgtgatct ttttcttttg catttcctta tacttggcaa
     1621 tctggtcgcg gaagtaggcc gccttctcaa aatcttcttc tcgtgtagct tgagacttga
     1681 gattttcagc ctcaatcaag cgctgatcaa ttactttagg atccacaaaa ttcaaggtca
     1741 agttcatctt agaaccagct tcatctagga ggtcaatggc cttgtcaggc aagaagcgat
     1801 cttggatgta gcgattggaa agagttgcag ctgcttcaat cgcagcatct gtatattgaa
     1861 cgtggtggta atcttcgtat ttcttttgaa tccctttgag aatagtgatt gtttcgtcca
     1921 ccgttggttc atcgacttta acaggctgca tacgacgctc gagggcagca tccttttcaa
     1981 tgatacggta ttcattgagg gtagtagcac cgactagttg cagttctcca cgagcaaggg
     2041 ctggcttgag gatatttcct gcgtccatat taccatcact cgcagaacca gcaccaacaa
     2101 tttcatggat ttcatcgata aagaggatga tgtcttcacg tttgcgaatt tcttccatga
     2161 gtttttgcat gcgttcttca aattgtcctc gaatccccgt tccttgaact aagctaacca
     2221 catccagacg gatgacttgt ttaccttgga gtttatgtgg cacatcgcca tcgacaattt
     2281 tctgagctag accttcgaca acggccgttt ttccgacacc aggttcaccg ataaggacag
     2341 gattattctt ggttctacga ttgagaatct cgatgacacg gataatctca tcgtcgcgcc
     2401 caataacggg gtcaatgtct ccacgacggg caatttcagt tacattaata ccaaattctt
     2461 ccagcaggcc tttttcttgg ctaggtggcg gagtttgagc agatccacga ttttgggaac
     2521 cataaccgcc gtttccaccg taacctccac ctgattgggt tgggggaata ggaggagtat
     2581 tgctagaagg tctgaaattg tttagatcat tgaagaaatc accaaaggga tcgaagtcac
     2641 gattgttcag atccgtcata cctttgaaga ggctattgtt aggatctgtt ttgataatct
     2701 tatagcagtt ttgacagagg tcaatttgtt tttgttttcc attgagattg gtgtaaagat
     2761 gaattgttga gtcgttaatt ttacagtttt gacaaagcat acatctacct catttctttc
     2821 tttagcctga cttgtttaaa ggtcaaaaat agtcaaattc tatactctca ttataacagg
     2881 attggggtgt aaagcaagta aaaagattga agctttgaga agttgttaca atgaaaattt
     2941 ttgtgaattt ggactataaa aaaatcctat ttgtgagaca aaaaggattt tacttagaca
     3001 tgcagggaca atcccagctt gttttagatt agtagagaag ttcgtaaatt tccattgcga
     3061 ttaagtcaat gctatcaaac gtatacgttt cgcgatcttc tacgtcacga agggtaaaga
     3121 ttgggccgtt ttcttcgtcg tggctgtacg caacttctgc aacaacaact ccttcgcgtt
     3181 caaaattacg ttttaaattt ccgccatcgt ttgccattgc ttcaaggcgg ttgatgattc
     3241 taaccaaatg tgattccatt ttgattctcc ttcatttctt atcgttacta ttttaccata
     3301 aaggaggcca acttgactag aaaaaactaa gatttctcgc taattctgct agtttaaaga
     3361 tttttaaata aattggataa aaaatttaaa ttttaattca aaacatgtta taatcataca
     3421 gtattctatt ttagaaagca gtgtgactat gaatttttct tttttaccta agtatttacc
     3481 ttattttaac tatggggctg ttgtgacgat tcttatttct atctgtgtta tctttttggg
     3541 aactattttg ggtgttgtct tggcttttgg gcaacgttca aagtttaaac cgcttgtttg
     3601 gttggccaac ttgtacgttt ggattttccg tgggacaccg atgatggttc aaattatgat
     3661 tgcctttgct cttatgcata tcaatgctcc gactattcag attggaattt taggtgttga
     3721 tttttcgcgt ctgattccag ggattttgat tatctctatg aatagtggtg cttatgtttc
     3781 ggagattgtt cgtgccggaa tcaatgcggt tccaaaaggt cagctagagg cggcttattc
     3841 gctagggatt cgtcctaaaa atgcgatgcg ttatgtgatt ttgccacaag cagtcaaaaa
     3901 tatcttgcca gcattgggga acgaatttat caccattatc aaggacagct ccctcttatc
     3961 agctattggg gtcatggagt tgtggaatgg ggctacaaca gtttctacaa caacctatct
     4021 acctttaaca ccacttttat ttgcagcatt ttactacttg attatgacct ctattctgac
     4081 agtagccttg aaagcttttg aaaaacatat gggacaagga gataagaaat aatgacagaa
     4141 accttgataa aaattgaaaa tttacataaa tcttttggaa agaatgaagt attgaagggc
     4201 atcaacctcg agattaaaag aggagaagtt gtcgttatca tcggtccttc agggagtggg
     4261 aaatctacct tgcttcgctc tatgaatttg ttggaggaag caaccaaggg gaaggttatc
     4321 tttgagggag tcgatattac ggacaagaag aatgacctgt ttgccatgcg tgagaagatg
     4381 ggcatggttt tccaacaatt taacctcttt cctaatatga ctgtgatgga aaatattacc
     4441 ttgtcaccta tcaagactaa aggtgaaagc agggaagttg ctgagaagag agcccaagag
     4501 cttttggaaa aagttggttt gccagataag gcagacgctt atccacagag tctgtcgggt
     4561 gggcaacaac aacggattgc catcgcgcgt gggttggcta tggaaccaga tgttttgctc
     4621 tttgacgaac caacttcagc cttggatcct gaaatggtag gtgaggtatt ggctgttatg
     4681 caagacattg ccaagtcagg gatgactatg gttatcgtaa cacatgagat gggatttgcc
     4741 cgtgaggtgg cagatcgtgt tatctttatg gcagacggtg tggttgttga agatgggaca
     4801 cctgagcaga tttttgaaca aacccaagaa caacggacta aagatttctt gagtaaggtt
     4861 ttataatcta ttttaaaatt tcaagacaag attagtgaaa agttcaacca gagctttttc
     4921 ttatagtttg aaactatagg ataacctagg aaagaagtgt tagagggcac tagcagtttt
     4981 tggtataatg gaagatattt gaaagaaaag agaagtgata tgacacagat tattgatggg
     5041 aaagctttag cggccaaatt gcaggggcag ttggctgaaa agactgcaaa attaaaggag
     5101 gaaacagctc tagtgcctgg tttggtagtg attttggttg gggataatcc agccagccaa
     5161 gtctacgttc gcaacaagga gaggtcagct cttgcggctg gttaccgtag cgaagtagtg
     5221 cgagttccag agaccattac tcaagaggaa ttgttagacc tgattgctaa atataatcag
     5281 gatccagctt ggcatgggat tttggtccag ttgccattac caaaacatat cgatgaagag
     5341 gcggttttat tagccattga cccagaaaag gatgtggatg gtttccatcc cctaaacatg
     5401 ggacgtcttt ggtctggaca tccagtcatg attccctcga cacctgcagg aattatggaa
     5461 atgtttcatg aatatgggat tgacttggaa ggtaaaaatg cggtcgtaat cggtcgttca
     5521 aatatcgttg gaaaacctat ggctcagctt cttttggcta aaaatgcgac agtaaccttg
     5581 acccactcac gaactcataa tcttgccaag gtggctgcta aagcagatat tcttgtagtc
     5641 gcaatcggcc gcgccaagtt tgtgactgct gactttgtca aaccaggtgc ggttgtcatt
     5701 gacgttggga tgaatcgaga tgaaaatggg aagctctgtg gagatgttga ttatgaggca
     5761 gttgcaccac ttgctagcca tatcacgcca gtccctggag gtgtcggtcc tatgaccatt
     5821 accatgctga tggagcaaac ttatcaagca gcacttcgga cattggatag aaaataagag
     5881 aagcattcga ttaatagagt gtattttcta tagctatatc taaaatggca gaaatgaata
     5941 ttaaatttta gatataagat tacaaaagga ggtctgcgtc tcctttttat tgtataataa
     6001 aagtgagagg aaaaaaggat gaaagtgatt aatcaaacct tattagaaaa agttattatt
     6061 gaacgttctc gttcaagtca taaaggagat tatggtcgtc tgctgctgct tggtggtact
     6121 tatccttatg gaggtgccat catcatggct gctttagcag ctgtaaaaag cggtgcagga
     6181 ttgatgaccg ttggaacgga cagggaaaat atcccggctc tgcacagcca tttacctgag
     6241 cctatggcct tttctcttca agaccagcaa ttgttaaaag agcaattgga gaaggcagaa
     6301 gttatcttgc tggggcctgg tttaggagac aatgcttttg gagaagattt agttaaacag
     6361 gtctttgctg gcttaaaaca gaatcagatt ttgattgtag acggaggtgc cttgaccatt
     6421 cttgctagga caagtttgtc atttccctca agccagctta tcctaactcc tcaccaaaaa
     6481 gaatgggaaa aattatctgg aattacgatt gaaaagcaaa aggaagatgc aacggctagt
     6541 gttctgactt ccttccctca aggaacaatt ttggtggaga aaggcccagc tactcgtatt
     6601 tgggaagttg gccaatctga ttattaccag ttacaggttg gtggtcctta tcaggcgact
     6661 gggggaatgg gagatactct ggctgggatg atcgcaggat ttgtaggcca attccgacag
     6721 gccagtctct acgagcgtgt ggcagtagcg acccatcttc attcagccat agcccaagaa
     6781 ctatctcaag aaaattatgt ggtcttaccg acggaaatca gcaggtatct tcccaaaata
     6841 atgaaaatta tttgtcaaca agagagggta agcaaagata aacttgttta aaatagacag
     6901 ataaatctac ttccttctct taatttatga ttcttgaaat gcgcctgctt taaggctaaa
     6961 ctagacgtat caaagttaag agtttgtttt tgtaactgga aagagatgaa caaatcaaat
     7021 acataaaaga taaactcatt tttattcgtt ttgtaaaaat aaaatgcata tttttaaaga
     7081 aagattgatg aaaaatgtag atttgatgtt tttacttgaa taaaaagcgg tttcatagta
     7141 aaataagaac tgagaatgat ggaggtaaat cggtggaaaa tctgaagaaa atggcaggta
     7201 tcaaggctgc tgagttcgtg agcgatggaa tggtcgttgg acttggaaca ggctcgactg
     7261 cctattattt tgtcgaagaa atcggtcgtc gtatcaagga agaaggattg cagattacag
     7321 ctgtaacaac ttctagtgtg accactaaac aggcagaagg ccttaatatc ccgctcaagt
     7381 ctattgacca agtagacttt gtcgatgtga cggttgatgg cgcggatgaa gtggatagtc
     7441 agtttaatgg aatcaaaggc ggtggtggtg cccttctcat ggaaaaggtg gtcgcaacac
     7501 catcaaaaga atacatttgg gtggtggatg aaagcaagct ggtcgaaaaa ctaggtgctt
     7561 ttaaattgcc agtagaagtg gttcagtatg gtgcagagca ggtctttcgt cattttgaac
     7621 gagctggcta caaaccaagt ttccgtgaaa aagacggtca acgttttgtg acggatatgc
     7681 agaattttat cattgacctc gccttggatg tcattgaaaa tccaattgct tttggacaag
     7741 aattggacca tgtcgttggt gttgtggagc atggtttatt caaccaaatg gtggataagg
     7801 taatcgttgc tggacgagat ggagttcaga tttcaacttc aaaaaaagga aaatagaagg
     7861 gggcataaga tgtctaaatt taatcgtatt catttggtgg tactggattc tgtaggaatc
     7921 ggtgcagcac cagatgctaa taactttgtc aatgcagggg ttccagatgg agcttctgac
     7981 acactgggac acatttcaaa aacagttggt ttgaatgtcc caaacatggc taaaataggt
     8041 cttggaaata ttcctcgtga aactcctctt aagactgtag cagctgaaag caatccaact
     8101 ggatatgcaa caaaattaga ggaagtatct cttggtaagg atactatgac tggacactgg
     8161 gaaatcatgg gactcaacat tactgagcct ttcgatactt tctggaacgg attcccagaa
     8221 gaaatcctga caaaaatcga agaattctca ggacgcaagg ttattcgtga agccaacaaa
     8281 ccttattcag gaacggctgt tatcgatgat tttggaccac gtcagatgga aactggagag
     8341 ttgattatct atacttcagc tgaccctgtt ttgcagattg ctgcccacga agacattatt
     8401 cctttggatg aattgtaccg tatctgtgaa tacgctcgtt cgattaccct tgagcgtcct
     8461 gcccttcttg gtcgcatcat tgctcgccct tatgtaggtg aaccaggtaa cttcactcgt
     8521 acggcaaacc gtcgtgactt ggctgtatct ccattttccc caactgtttt ggataaattg
     8581 aatgaggctg gtatcgatac ttatgctgtg ggtaaaatca acgatatctt taacggtgct
     8641 ggtatcaacc atgacatggg tcacaacaag tcaaatagtc atggaattga tacactattg
     8701 aagactatgg gacttgctga gtttgaaaaa ggattctcat tcacaaacct agttgacttt
     8761 gatgcccttt acggccatcg tcgtaatgct cacggttacc gtgattgctt gcatgagttt
     8821 gatgaacgct tacctgaaat tatcgcagct atgagagaga atgaccttct cttgattact
     8881 gcggaccatg gaaatgaccc aacgtatgca ggaacggatc acactcggga atatattcca
     8941 ttgttggcct atagccctgc ctttaaagga aatggtctca ttccagtagg acattttgca
     9001 gatatttcag cgactgttgc cgataacttt ggtgtggaaa ctgctatgat tggggaaagt
     9061 ttcttagata aattggtata agatgacgcg ctatgctttg ctggtgagag gtatcaatgt
     9121 tggtggtaag aataaggtcg tcatggcgga gcttcgtcaa gaattgacaa acttgggact
     9181 ggaaaaggtt gagagctaca tcaatagtgg caatattttc tttacttcga tagattccaa
     9241 agcccaattg gttgaaaagc tagagacttt ctttgcagtc cattatccat ttattcagag
     9301 cttttcttta ctgagtctag aggactttga ggcggaactt gaaaatctac cagcttggtg
     9361 gagcagagac ttggcacgaa aagattttct cttttacact gagggtttgg atgtggacca
     9421 agtcatcgcg acagttgaaa gtttagagct gaaagatgaa gtgctttatt ttggaaaact
     9481 tgggattttc tgggggaaat tttctgaaga atcctattct aagactgcct atcataagta
     9541 cttgctgaag gtgcctttct accgccacat tactattcgt aatgctaaaa cctttgacaa
     9601 aattggtcaa atgctaaaaa aataataaag gagacacaca atgacatttt taaacaaaat
     9661 ccatgaaact gctactttcc tgaaagaaaa gggaattgca gcccctgagt tcggtctaat
     9721 ccttggatca ggacttggag aattggcaga agaaatcgaa aatccagttg tagtagacta
     9781 tgctgagatt ccaaactggg gccgttcaac agtagtcggt catgctggta aattggtata
     9841 tggtgaactg gcaggtcgca aggtcttggc tcttcaaggg cgtttccatt tctatgaagg
     9901 gaatcctctg gaagtggtga ctttcccagt tcgtgtgatg aaagttcttg gatgtgaagg
     9961 tgttattgta accaatgcag ctggcggtat cggatttggt cctggtacct tgatggctat
    10021 ctcagaccat atcaacatga cggggcaaaa tccattgatg ggtgaaaact tggatgactt
    10081 tggcccacgt ttcccagata tgtctagggc ctacacacca gaataccgtg ccactgccca
    10141 tgaagtggct aaaaaactta atatcaagct tgatgaaggt gtctatatcg gagttactgg
    10201 tccgacttat gaaacaccag cagaaattcg ttcctataag acactgggag cagatgcagt
    10261 tggtatgtct acggttcctg aagttatcgt ggcagcccac tctggcttga aagttctggg
    10321 aatttcatgt atcactaact ttgcggccgg tttccaagaa gaactcaatc acgaagaagt
    10381 tgtagaagtg actgaacgtg ttaaaggtga tttcaaaggc ttgcttaaag cgattcttgc
    10441 tgaattgtaa gaaaaaagat ttaaaagggg gagtgcctct gttttttcag gattgactgc
    10501 ctatccggat taaagaagaa acagaggaat actatgagct tcttcctgct cttataactg
    10561 aaagaagcgg aagaataggt atgtctgatc tgatagccag cattgtgaaa gacaagattc
    10621 taggatacta gcattagctt cctagccaag cagactagta tgataaggag agatgagaat
    10681 gaattgactt tctgaatttc tcagtcttat catatatagc acaatgagat ttcgcttgag
    10741 tctgcttgta aataaacgaa aagaaagata agaaataatg aaaattggtc aacgaattat
    10801 gcgctttggc ataaaaaatt aagtatcgga gttgtatctg ttgtagtcgg ctttgatttc
    10861 tagctccagc tggaatttca gccaatgaag taaagcaaga tgtaacatct gaagtggtaa
    10921 taggtgtgct agattctaag gaggaattga aagagtcaga aaatgatgct ccaaaactag
    10981 aaactcctct tagagaggag ccaagactag ctcctcaaac gcttccggaa gcaagtgaag
    11041 ttcttgaaaa caaaagggaa gagtcaaaag tagagataac ataaccagct caagcggatg
    11101 atatccgcaa ggttgttggg gaattagcca aggatataag tattactaag ttgtatatga
    11161 caggtcattc tcttggatgt tacctagctc agattgcagc ggttgaagct taccaaaaat
    11221 atcctgattt ttataaccat gtattgagga aagtgacaac tttcagtgct cctaaagtga
    11281 ttacttccag aactgtttgg aatgctaaga atggtttctg ggatgttggt ttggaaagtc
    11341 gtaaattagc tgttagtgga aaaattaagc attatgtggt tgataatgac aatgttgtga
    11401 ctcccttgat tcataataat cgtgatattg ttacatttac aggtaattca cgctttaaac
    11461 accgttctcg tggctatttt gaaagtccaa tgaatgatat tcctaacttt aatattggta
    11521 aacaagctac cttggataaa catggttatc gtgatccgaa attggataaa gtgcgattct
    11581 ttaagaaaca ggctctgcct cgatcttcta gtcaaccaag cgctgaacca atggaaaata
    11641 ttgccttagg aaaacaggtt actcaaagtt cgacagcttt cggaggagat gctagaagag
    11701 ctgtggatgg caaagtcgat ggtaactatg gtcacaattc tgtcactcat acaaacttcc
    11761 aatctaagcc ttggtggcaa gtagatttgg ctaaagaaga aaccattcgc caaatcaata
    11821 tttacaaccg aacagacact gcccaggata gattggcaaa ctttgatgtc attcttttag
    11881 acagttctgg taaagaaatt gagtgaaaac gtataatatc tcctaaagat gtgtcagcac
    11941 aaattacgat taaccataaa aaagcgcgct atgttcggat tgagctagaa ggctataatg
    12001 ccctcagtct tgcagaagtt gaagttttcc gctttatagc tacgaatgct gaaacggcga
    12061 cacaagtttc taagccagtt caaccaatca gtcagactcc tgtgaaagat aaaacattga
    12121 caattcaaca cagtggagct tacattgccc gctactccat aacttgggaa gaagttccag
    12181 tagataaaga tggaaaccaa gttgttcgta gtcattcttg ggaaggaaac ggtcgcaacc
    12241 agactgcggg ttttgtcctc aacctcccaa tcaaagaaaa tatgagaaat ctgcgagtta
    12301 agattgagaa aaagacgggc ctactatgga atagatggca aacaatctat gaaaacagac
    12361 caatttcagc tcaaccccac cgtaaaatta cccattgggg tacgacattg aattccaagg
    12421 tgagtgacga tgatgtcttg taatctgatg gtacaatgac agttagtttg tctagtttat
    12481 aagaaagtac tacctgagct tgaatagaac tcaggtagct ctctgtgaaa gaacaaaatt
    12541 aatactcaat gaaaatcaaa gagcaaacta ggaaactagc cgcaggttgc tcaaagcact
    12601 gctttgaggt tgtagataag actgacgaag tcagtcacat atataatcca aggcgacgtt
    12661 gacgtggttt gaagagattt tcgaagagta taaacagaaa ggtagagcgc gtgttctaat
    12721 ttgaacacga gtagaaaact tttctaaaaa caaaaacgaa aggatgggta aactgtattc
    12781 gctgaactga atacgggcga ctctcctcta aatcaaaatt aagaaaggaa ttgaccccac
    12841 cctaaaagta gtgggaaaaa gatagttggt ctagcgagca tcgctcactg cgcccaactc
    12901 ctattttccc ttcgcttttt gatgggtttg gtatctttct caatataaaa taaagaaagg
    12961 tagagcgtgt gttttgattt gaacacgagc ggaaaactcg gaaaatagat aatctgactg
    13021 aaaaatcagg atttctcgtc aggttcctaa ttttcagtcg ttttcttctc gctctttgta
    13081 tcataaatta tgtctatcca tattgctgct cagcagggtg aaattgctga taaaattctt
    13141 cttcctgggg atcctcttcg tgctaagttt attgcggaga atttccttga tgatgctgtt
    13201 tgttttaacg aagtgcgtaa catgtttggt tacactggta cttacaaggg tcactgtgta
    13261 tctgtcatgg gaactgggat gggaatgcca tctatttcga tttatgcgcg tgagttaatc
    13321 gtagactacg gtgtgaagaa attgattcgt gtgggaactg caggttcttt gaatgaagag
    13381 gttcatgttc gtgaattagt tttggcgcag gcggctgcaa ccaactcaaa catcgttcgt
    13441 aatgactggc cacagtacga ttttccacaa attgctagct ttgatttgct tgataaagcc
    13501 taccatatcg ccaaaaaact tggtatgact actcacgttg ggaacgtttt gtcatctgat
    13561 gtcttttact caaattactt tgaaaagaat atcgagcttg gtaaatgggg agtcaaggct
    13621 gtggaaatgg aagcagcagc tctttactat cttgctgccc aataccatgt tgatgcgcta
    13681 gctatcatga ccatctctga tagcttggtc aatccagacg aagacacaac tgcagaagaa
    13741 cgtcaaaata ccttcactga tatgatgaag gttggtttgg aaaccttgat tgcagaataa
    13801 ttatagccaa aaaggaagcc ctttatgaat tgtaggactt ccttttctta tccagaaatt
    13861 gatctagctc tctctgattt cgaagaatag tgactttatg tgaatattct tggcaaagtt
    13921 tttggtaatt ttctttttga gttttgctac gcccatccca aagaatccat ctgataaact
    13981 cccactcaaa gcgttcaggg caatctgccg ccatactttc tctgactttt ccacggtatt
    14041 taagataacg cttaaaggct ctaaagagac aggtcaatgg cgaaaaattg agaaagatga
    14101 tttggtcagc ttcttgcatt cgttcttggt agtagcacca agaataatta ccatcgatga
    14161 cccaagcttt atgcttggtg agaaagtttt ttatctcggt taacatccat tcgcagtcac
    14221 tgtcttgcca accaggttga aattggagtg tgtccatgtg cagttttgga atggagtagt
    14281 agttagataa cttttctgct atagttgact taccagaacc agaatatccg ataattgcga
    14341 ttttcatttt ctactttttc ctatttggag acaaaaaaac agcctctatg gactgtttct
    14401 tatttagcaa gtttagctga aagacgagct ttatcgcggc ttgctttgtt tttgtgaatc
    14461 aaacctttag tttctgcttt atcgatagct gagctagcag cacggaaaag ttcttcagat
    14521 gggtttgctt cgaaagcttt tatagcagta cgcatagctg atttttgagc tgagttcttt
    14581 tcgttttgtt taacgttcaa ttcagcgcgt ttgatagctg atttaatgtt tgccaatgtt
    14641 cttacctcca tatttactaa ctataccatt atatatgaaa acttacgttt tgacaaggga
    14701 aaattacttt tttaagtaaa tttcatcgat ttcatggttc ttgcttttat gaagaatcac
    14761 ttctgcacga tttctggttg gttcaatata attttgcaga tttgtgagat tgatactgat
    14821 ccagacctga tgggcaaagg actccacttc cccaatcggc atctgagtaa aacgataata
    14881 gtagctatca gggtcgtttt gggctaggct cagcattttc aagaaacggt ccagatacca
    14941 actttcaata tcatccactc cagcatctac atagatggaa aagtcaaaga agtcagtgat
    15001 atagagacga tcgttttgtg gattttgaaa gacattaatt ccctcaacaa ttacaaaatc
    15061 agcagctttg acactttgtt tcttttcggg tacgatgtcg taaacttcat gagaatagac
    15121 aggaatatct acatcttgtc catttttgat gcggtccaag aagttgagaa gagcttccat
    15181 atcatagctt tcaggaaatc ctttacgatt taaaatcccc tgctcaatca aggtttgatt
    15241 gggatagaga aaaccatcag ttgtaaccaa ctcaaccgta gcatctgtaa acgtacggga
    15301 cagtaggatt tgaagtaggc gactggttgt ggattttcca acggcaacac tcccagaaac
    15361 cccaataata aaaggttgag atttactttc acgttggagg aaaattcctt ttgaaaaggc
    15421 taaatcttcc ttagttcgct tgtaaatctg aatcagatga gccaagggga gatagatatc
    15481 tgtaacgtct tggagactga tttggtcatt aaaactcttg atagattcca attcttcttc
    15541 tgtcaaagga ggtgttgtct ttcgatgtaa agattgccaa gtctggcggc tgattttttc
    15601 aaaatgtaaa aattcgttgg tcatttgttt tcccctagat attttgtcta tcataccata
    15661 aaaagctaaa aaaataaagc ggtttcttga atgtggtaag tcaatggtat atagtataag
    15721 tgatcaattt attgatgaaa taggagatag attctactga tttataagct tataaagggg
    15781 gctttttagt tcacaactta taggaggtgt actatgaaaa tcttaaaacg ttacatattg
    15841 gaactctgtt ttattttaag ttttgcttta ccttttataa aaggaaccaa tgcagataat
    15901 ggtagatgct ttgtggaaac ctattacggt tttacttttt tgatggaaca tgctattgta
    15961 acagctgtct ttatctattc gtttttaatt gctttcttac taaaaaaacg atgggcgaaa
    16021 tggattgctg ctggtagtta ttgcttttta gtcctatgga ttgcgacaga gggttatttc
    16081 ttccgcatgt cactagaaga tttgatacga ctttggacaa gtttggaaat cctgacacaa
    16141 acgtatcagt tgggctttta tctaaacatt ttgttaggaa ttttgttgat aataaagtat
    16201 tttaaggtta agcaatagaa ataataatct gcctgattat agatgataaa ctttttgttt
    16261 ttatctggac tgtgatattt atagttctaa atggtttatt atttataagt gttgaaagag
    16321 attgaagaaa atggcttcgt gacttgcttt cttcggtctt tttcgtttta ttatcaattt
    16381 gtaaacgatt tacaatttga gtcaaattat ggtaaaatag tgtcatgagt aaaatgtatt
    16441 atgcagaaaa tcctgacgct gctcacgaca ttcatgagtt gagagtggac ttgttgggac
    16501 aaaaaatgac ttttttgaca gatgcgggtg tttttagcaa gaaaatggtt gactttggaa
    16561 gtcaactctt gctcaagtgt ctggatgtca accaaggaga gacagtccta gatgtaggct
    16621 gtggttatgg tccattaggt ttgtccttgg tcaaggttta cggagttcag gcgaccatgg
    16681 ttgatattaa cactcgtgcc ttggatttag ctcggagaaa tgctgaaaaa aataatgcaa
    16741 aagcgacgat tttccagtcc aacatctatg aacaagttga aggacatttt gatcatgtca
    16801 tttccaatcc tcctatccgt gcgggcaagc aagtcgttca tgaaatcatt gagaaaagta
    16861 aagatttctt ggaaactggt ggggatttga caatcgtcat ccagaaaaaa caaggggctc
    16921 caagtgctaa gtccaagatg gaggatgtgt ttggtaattg tgaaatcctt aaaaaagaca
    16981 aaggatacta tatccttaga agtgtgaaag aatgagagca gttgatttaa tacaaaaaaa
    17041 acgagacggt caagaactga cttcaagtga aattgaatgg ctggtagaag gctatgtgtc
    17101 aggaactgtt cctgattatc agatgtctgc ctttgctatg gctgtttatt ttaaaggaat
    17161 gacgactcgt gaaatttctg atttaacgat gaatatggtt aagactgggc aagagtttga
    17221 cctgtcagcc attgatggtg tgaaagttga caagcattct actggtggtg tcggcgataa
    17281 ggtaaccttg attttagctc ctcttgttgc tagcttcggt gtgcctgtag caaaaatgag
    17341 tggtcgtggt cttggccata caggcggaac aattgataaa ttggagtcca ttaggggcta
    17401 tcaagtagaa cgtagtcaag aggattttat tcgtcaggtt caggatattg gagtatctgt
    17461 cattgggcaa tcagaccagc tggtcaaagc agataagctt ctctatgccc ttcgtgatgt
    17521 gaccgcaact gtcgacacga ttcctttgat tgcgagttcg gtgatgagca agaaaattgc
    17581 ggcaggggcg gatgctattt tgctagacgt gactgtcggt gagggtgcct tcatgaagac
    17641 ggttgatgag gcgcgtgagt tggctcaaac tatggtagat cttggtaagg ttgttggacg
    17701 gaagacagta gcagtgatta cggatatgag ccagcctttg ggacgagcga ttggaaatcg
    17761 tctggaaata cttgaagcat tggagatttt gcaaggtcaa ggacgtcagg atattaccca
    17821 ctttatttgt gaattggctc aaattatgct tggtttggca aatgttaaca agactgttga
    17881 agaagttcac caacatcttg agaatggtca agcactggct aagtttgagg aaatggtgca
    17941 agcccaaggt ggagacttgg aagacctcta tcgtcctgta aatgtagctc atgtggtgga
    18001 aatccctgct caggaaacgg gtgtcatttc agctcttcca gctatggact ttggtcttta
    18061 tgccatgagg ctgggggctg gtcgtgcagt taagtctgat gccttggact atgaaacagg
    18121 aattgttttt gaaaagaaga ttggagactc cgttcaaaag ggtgaaattg ttgcaaaagt
    18181 atacacaaat gaaaaaattc cacctcaact agttacagat ttccaaaaat gtgttaaaat
    18241 aagtgatgaa gtgaaaaaaa tccgtgaaat tgtagaaatc atctcctaaa tggagggaaa
    18301 accgaaatga aattaaataa atatatagat catacgcttt taaaacaaga tgcaaagaaa
    18361 aaacaaattg atagtttgtt gtctgaggct agagagtatg actttgccag tgtttgcgtt
    18421 aatccgacct gggttgaaca tgctaaaaaa ggacttgaag gcacagatgt taaggtttgc
    18481 acggtagtag gtttcccttt gggagcaaca acttcagccg tgaaagcatt tgagacaaaa
    18541 gaagctatcc aaaatggtgc agatgagatt gatatggtga tcaatgttgg agctctcaaa
    18601 tcaggtaatt tagccttggt tgagtcagat attcgcgcag tagtggaagc aagtggtgat
    18661 aagttagtga aagtcattat tgaagcttgc cttctgacag accaagaaaa aattgttgtt
    18721 tgccaattgg cccaaaaagc tggggctgac tttgttaaaa catctactgg tttttcaact
    18781 ggtggtgcta cgatagcaga tgttacatta atgcgtgaaa cagttggatc tgatatggga
    18841 gtcaaggctg ctggtggagc tcgttcttat gcagatgctc ttgcctttgt cgaagcaggt
    18901 gcgacccgta tcggaacgtc agctggggta gctattttaa aaggagaatt ggcagatggc
    18961 gactactgag ttgattgaac tggcaattga aaccagcaaa catgcctatg tcccctattc
    19021 tcactttcct atcggagcag ttttagtagc caaagacgga agtgtttaca cgggagtgaa
    19081 tatcgaaaat gctagctatc ctttgaccaa ttgcggtgag agaacagcta tttttaaggc
    19141 tatatctgaa ggccaaagag aattttcaga attgattgtc tatggtcaaa ctgaaaaacc
    19201 gatctcgcca tgtggtgctt gtcgccaagt gatggctgaa ttttttgaac aagatctaaa
    19261 agtgacctta gtcgcaaaag ataaatcgac ggtcgagatg acggtcgggg aattacttcc
    19321 atactctttt acagacttaa actagtctga gtcgctctct gagtggcacg gtccttgtgg
    19381 ccaaccaatc catacttgca acatcgttgc acatcttatt taggaggttc agtaatgaac
    19441 aagaaacaat ggctaggtct tggcctagtt gcagtggcag cagttggact tgctgcatgt
    19501 ggtaaccgct cttctcgtaa cgcagcttca tcttctgatg tgaagacaaa agcagcaatc
    19561 gtcactgata ctggtggtgt tgatgacaaa tcattcaacc aatcagcttg ggaaggtttg
    19621 caggcttggg gtaaagaaca caatctttca aaagataacg gtttcactta cttccaatca
    19681 acaagtgaag ctgactacgc taacaacttg caacaagcgg ctggaagtta caacctaatc
    19741 ttcggtgttg gttttgccct taataatgca gttaaagatg cagcaaaaga acacactgac
    19801 ttgaactatg tcttgattga tgatgtgatt aaagaccaaa agaatgttgc gagcgtaact
    19861 ttcgctgata atgagtcagg ttaccttgca ggtgtggctg cagcaaaaac aactaagaca
    19921 aaacaagttg gttttgtagg tggtatcgaa tctgaagtta tctctcgttt tgaagcagga
    19981 ttcaaggctg gtgttgcgtc agtagaccca tctatcaaag tccaagttga ctacgctggt
    20041 tcatttggtg atgcggctaa aggtaaaaca attgcagccg cacaatacgc agccggtgca
    20101 gatattgttt accaagtagc tggtggtaca ggtgcaggtg tctttgcaga ggcaaaatct
    20161 ctcaacgaaa gccgtcctga aaatgaaaaa gtttgggtta tcggtgttga tcgtgaccaa
    20221 gaagcagaag gtaaatacac ttctaaagat ggcaaagaat caaactttgt tcttgtatct
    20281 actttgaaac aagttggtac aactgtaaaa gatatttcta acaaggcaga aaaaggagaa
    20341 ttccctggcg gtcaagtgat cgtttactca ttgaaggata aaggggttga cttggcagta
    20401 acaaaccttt cagaagaagg taaaaaagct gtcgaagatg caaaagctaa aatccttgat
    20461 ggaagcgtaa aagttcctga aaaataatgg atggaagtca tttcttagga agcggccaag
    20521 ggccgctttt ttaagagttg agacaaagtc attttgtctc agtaaagctt gctactagac
    20581 aaactagcaa gttttattga aataaaataa gactctgaaa ggaagagcac atggcacacg
    20641 aaaatgtcat tgagatgcgt gatattacca aggtgtttgg tggatttgtt gccaacgaca
    20701 aaatcaactt gcacctacga aaaggtgaaa ttcatgcact tttaggagaa aatggggctg
    20761 gtaagtccac gctaatgaac atgttagcag gccttcttga accaactagt ggtgaaatcg
    20821 cggtcaacgg tcaagttgtc aatctcgact ccccatctaa agcagctagc ttgggaatcg
    20881 ggatggttca ccagcacttt atgttggttg aagccttcac agtggctgaa aacatcattt
    20941 taggtagtga attgactaaa aatggtgtgc tagatatcgc tggagctagc aaagaaatca
    21001 aggctctttc tgaacgttat ggcttagctg ttgacccttc tgccaaggta gcagatatct
    21061 cagttggagc ccaacaacgt gtagaaattt taaaaacact ttatcggggg gctgatatcc
    21121 ttatctttga cgaaccaacg gctgttttga ctccatcaga aattgatgag ttgatggcta
    21181 ttatgaaaaa tcttgtcaaa gaaggaaaat caattatctt gattacccac aaattggatg
    21241 aaattcgcgc agtttctgac cgtgttacag ttatccgtcg tgggaaatca attgaaaccg
    21301 ttgaaattgc aggggctacc aatgctgatt tggcggaaat gatggtagga cgttctgttt
    21361 cctttaaaac agagaagcaa gcctctaaac caaaagaagt ggttttgtct atcaaagatt
    21421 tggtggtcaa tgaaaaccgt ggtgttccag ctgttaaaaa tctgtccttg gatgttcgtg
    21481 ctggagagat tgttggtatt gcggggattg atggaaatgg tcagtctgaa ctgattcaag
    21541 ccattacagg tcttcgtaag gttgaatctg gtagcattga gctaaaagga gattcaattg
    21601 taggcttgca cccacgtcag attacagaac taagtgttgg gcacgttcca gaagaccgtc
    21661 accgtgatgg cttgattttg gaaatgatga tatctgaaaa tattgccctt caaacctact
    21721 ataaagaacc acatagtaaa aatggaattt tgaattattc aaatattact tcttatgcta
    21781 aaaagctgat ggaagagttt gatgttcgcg ctgccagtga attagttcct gcagctgcac
    21841 tctcaggagg aaatcaacaa aaagcaatta ttgctcgtga aattgatcga gatcctgatc
    21901 tccttatcgt tagccagcca actcgtgggt tggatgtcgg tgccattgag tatatccaca
    21961 aacgcttgat tgaagagcgt gataatggca aggctgtcct tgttgtcagc tttgaattgg
    22021 atgagatttt aaacgtctca gaccgtattg ccgttatcca cgatggtaag attcaaggta
    22081 ttgtatcacc agaaacaacc aataaacaag aacttggtgt cttgatggct ggtggaaact
    22141 tgggaaagga gaagagtgat gtctaaaaaa ttacaacaaa tttcggttcc cttgatttct
    22201 gtatttctag gaattttact cggagccatt gtcatgtgga tcttcggtta tgatgctatt
    22261 tggggctacg aagaattgtt ctatacagcc tttggcagtc tgcgtgggat tggagaaatc
    22321 ttccgtgcta tgggtcctct ggtcttgatt ggtcttggtt ttgcggttgc cagtcgagct
    22381 ggtttcttta acgtcggact tcctggtcag gctttggcag gttggattct cagtggttgg
    22441 tttgcgctgt cgcatccaga tatgccccgt cccttgatga ttctagcaac catcgtgatt
    22501 gccttgattg ctggtgggat tgtcggagcg attccaggta ttcttagggc ctatctaggg
    22561 acgtcagagg ttattgtaac catcatgatg aactacattg tcttgtatgt agggaatgcc
    22621 tttatccatg ctttccctaa agacttcatg caaagtacag attcgaccat tcgtgttggg
    22681 gctaatgcaa cctatcagac accttggttg gctgagttga ctggtaactc acggatgaat
    22741 attggtattt tctttgccat cattgccgtt gcagttattt ggttcatgct caagaaaaca
    22801 actcttggtt ttgaaatccg tgcagttggt cttaatccac atgcttcaga atatgctggt
    22861 atttctgcca agcggactat tatcctatct atgattattt caggtgcctt ggcaggtctt
    22921 ggtggagctg ttgaaggttt gggaaccttc cagaacgtct atgttcaagg ttcgtcatta
    22981 gctatcggat ttaacggaat ggcggttagt ttgcttgcgg ccaactcacc aattggtata
    23041 ctctttgcag ccttcctatt tggcgttctc caagttgggg ctcctggtat gaatgcggcg
    23101 caggtaccat ctgagcttgt cagcattgta acagcgtcta ttatcttctt tgtcagtgtt
    23161 cattacctta tcgaacgctt tgtcaaaccg aaaaaacaag ttaaaggagg taagtaaaga
    23221 tgtctattat aaccttgctc cccctcttgg tgtcttctat gctgatttac tcagcacctc
    23281 tcatctttac aagtatcggt ggtgttttct ctgaacgtgg tggtgtggta aacgttggcc
    23341 ttgaaggaat tatggttatg ggtgcctttt ctggagttgt ctttaacctt gaatttgcag
    23401 aacaatttgg agcagcaact ccatggctat ccttgcttgt agcaggattg gttggtagtg
    23461 ttttctctat catccacgca gcagcgacgg ttcatttccg tgcagaccat gttgtcagcg
    23521 gtacggtatt gaacttgatg gcgcctgcct tggctgtttt cttagttaaa gttctttata
    23581 acaaaggaca aaccgacaac ctaagtcaaa cttttggacg ctttgatttc ccagtcttgg
    23641 caaatatccc agtgattggt gatatcttct tcaagtcaac tagtctactt ggttatctgg
    23701 cgattgcctt ctcattcctt gcttggttta ttctctttaa gactcaattt ggtcttcgtc
    23761 tccgctctgt cggtgaacat cctcaagcag cggatacctt gggaatcaac gtctacaaga
    23821 tgagatattt agggattatt atttcaggtt ttctaggtgg aattggcgga gcgatttatg
    23881 cgcaatcaat ctcagttaac ttctcagtga caactattgt tggacctgga tttatcgccc
    23941 ttgctgcgat gatctttggg aaatggaatc caatcggtgc tatgctttct agtctcttct
    24001 ttggactttc acaaagtttg gctgttatcg gttctcaatt gccgttccta caaggagtgc
    24061 cagcggttta tcttcaaatt gcaccttatg ttttgacaat tcttgtctta gcagccttct
    24121 ttggaaaagc agtcgcacca aaagcagatg gtatcaacta catcaaatca aaataagcat
    24181 acaaaaaaac gtcagtccaa tgactgaact gccccccaaa agttagacag aaaaaatcta
    24241 acttttgggg tg
//
LOCUS       DAVBEO010000033        23312 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 009
            SAMEA1678075-rid20185393.denovo.033, whole genome shotgun sequence.
ACCESSION   DAVBEO010000033 DAVBEO010000000
VERSION     DAVBEO010000033.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678075
            Sequence Read Archive: ERR226392
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 23312)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23312)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980207.1
            Genome Coverage       :: 150x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:50:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 72 of 147
            Pseudo Genes (incomplete)         :: 72 of 147
            Pseudo Genes (internal stop)      :: 42 of 147
            Pseudo Genes (multiple problems)  :: 32 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23312
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678075-rid20185393.denovo.033"
                     /strain="KS 009"
                     /db_xref="taxon:1313"
     gene            complement(196..654)
                     /locus_tag="VQ543_001340"
     CDS             complement(196..654)
                     /locus_tag="VQ543_001340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3021 domain-containing protein"
                     /protein_id="HET2612059.1"
                     /translation="MKKQVFHDAAAGVLIGLILSILFSLIYAPNTYAPLNPYSLIGQV
                     MDQHQVHGALVLLYCTLIWAAIGMLFNFGNRLFSRDWSMLRATLTHFFLMLAGFVPLA
                     TLAGWFPFHWIFYLQLIIEFAIVYLIIWAILYKREAKKVDHINQLLEHRK"
     gene            complement(651..1091)
                     /locus_tag="VQ543_001341"
     CDS             complement(651..1091)
                     /locus_tag="VQ543_001341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000861967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET2612060.1"
                     /translation="MKVELQISETYEEEKLIVQAPQPTDKVQKVIEFAENLDQREKIK
                     GKIDDQVYLVEIGKIQRFYIENRKVLAETASQTYSIDLRLYQVLKLLPTNFIQISQSE
                     IINIDSISHLKLTPNGLVEIFLKNESFTYSSRRYLKTIKEKLEL"
     gene            1675..2541
                     /locus_tag="VQ543_001342"
     CDS             1675..2541
                     /locus_tag="VQ543_001342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000537001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET2612061.1"
                     /translation="MGTLLATRLKNRRKELKMSQRELAEGICKQGQISRLESGEFTPG
                     ADFLHALAKKLKVSMDYFFDEQVVEKVEELSEFKKLAQTFITNRNYESLKYIYELENV
                     KAHRLSLADKIYMEWIKSLIDFYFYGQKEDAIVRLEGVLSQLSVSDLNYLQVSNTLFN
                     FYYDIGDLGRFNKIREKLEYQVNHLNLSTIEELELSIKFNYNVCRYLWLQKNIEEAIT
                     KITATIKQCKAYRTNYLLADLYLLMGNVSENFSSKSSVKEYFETAYFLYKLEENMSMT
                     LKVEHYIADITE"
     gene            2878..3435
                     /locus_tag="VQ543_001343"
     CDS             2878..3435
                     /locus_tag="VQ543_001343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenate--cysteine ligase family
                     flavoprotein"
                     /protein_id="HET2612062.1"
                     /translation="MDKKNLLVLVTGSVGASNVDTYLYYIKKFYNVKVILSENSKKFI
                     SKELISYFCDKVYDEIFVEEVVPHVFLPYESDLLLILPATANVIGKIANGIADDLVTA
                     TVLNFNKKIIFCPNMNSTMWDNHIVQRNVSILKELGHIFLFESKKTYEVGLRKAIDST
                     CSMLQPQSLVKELIKLENIVLEEGH"
     gene            3656..4762
                     /locus_tag="VQ543_001344"
     CDS             3656..4762
                     /locus_tag="VQ543_001344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000608718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal-dependent decarboxylase"
                     /protein_id="HET2612063.1"
                     /translation="MINKKIQQVVLESLQNFLNGNFISPCVVYDFGLLETVLDEFKNQ
                     IPVTFNYQLFYAVKANSNEKILEFLVDKIDGVDVASLSELDVAKKFFPPTQISVNGPA
                     FSYETLYNLIKKQYKVDINFLEHLQQFSPKESVGIRVTEPDELNNRMSRFGINICSDN
                     WTSNLQNPLITRLHFHFGEKDDKFIVKLDKILFKLQEINKLREVREINLGGGFMKLFM
                     ENRLKEFFLSLMEIYKKYDIDSTVTTIIEPGSAITSFSAYMITSPVNVSEVNEQQVIT
                     LDTSIYTNTLWFVPHIITTLNSSSKERYSTILYGNTCYEHDKYKMKVSLPRLTQNSSI
                     VFFPVGAYIKSNHSNLHRNDFMREVYLWTKNLTY"
     gene            4738..6129
                     /locus_tag="VQ543_001345"
     CDS             4738..6129
                     /locus_tag="VQ543_001345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2612064.1"
                     /translation="MDKKLDILDKVKEYLGNKTTQILDNQYKEFLKLNDIRRAFGISE
                     KVLNNSFNFTSKEFNDLINNENYLFEYACRIREEWRKKCFNHSYRFLCSPIITDDFLN
                     TKTLRSSQIEYKYERYLSKSSIGDRAVDGFVSFNTLTANGMSAIKLCLEILNSIFFKK
                     KIDLLYSTGYYETRFLLNNLAKSGISCYEVSNCELDKDKFYNVFMMEPNRADLTLQKT
                     DFKIVEYFVKYKNNSIKVVILDISYQGSNFKLVEFLEKFKFANVIIFVVRSLIKLDQM
                     GLELTNGGIIEVFIPNHLRKLKNFIEEEFNKFRNSHGANLSLYEYCLLDNSLTLKNDW
                     NYSDLVMKFTSNFYADIKDLFMENSDIEIIHEEGVPFVFLDLIGEGKKEYEMFFQWLN
                     FFYKQLGITLYARNSFGFRNLTVEYFGIIGTERYIFKICPGVYKGLSYYLMKFLLKSF
                     SNEYLKTTDEVNR"
     gene            6126..7304
                     /locus_tag="VQ543_001346"
     CDS             6126..7304
                     /locus_tag="VQ543_001346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000792992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HET2612065.1"
                     /translation="MKNLIKLLIIRLIVNLADSVFYIVALWHVSNNYSSSMFLGIFIA
                     VNYLPDLLLIFFGPVIDRVNPQKILIISILVQLAVAVIFLLLLNQISFWVIMSLVFIS
                     VMASSISYVIEDVLIPQVVEYDKIVFANSLFSISYKVLDSIFNSFASFLQVAVGFILL
                     VKIDIGIFLLALFILLLLKFRTSNANIENFSFKYYKREVLQGTKFILNNKLLFKTSIS
                     LTLINFFYSFQTVVVPIFSIRYFDGPIFYGIFLTIAGLGGILGNMLAPIVIKYLKSNQ
                     IVGVFLFLNGSSWLVAIVIKDYTLSLILFFVCFMSKGVFNIIFNSLYQQIPPHQLLGR
                     VNTTIDSIISFGMPIGSLVAGTLIDLNIELVLIAISIPYFLFSYIFYTDNGLKEFSIY
                     "
     gene            7729..7962
                     /locus_tag="VQ543_001347"
     CDS             7729..7962
                     /locus_tag="VQ543_001347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000623387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HET2612066.1"
                     /translation="MISIDLGGTNIKITVLSNDGEIETLWSITTDTSEKGSQIISDII
                     SSIKNKLTERNIPDSDLLGIGMGSCSSYFPCKS"
     gene            8245..10194
                     /gene="mutL"
                     /locus_tag="VQ543_001348"
     CDS             8245..10194
                     /gene="mutL"
                     /locus_tag="VQ543_001348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair endonuclease MutL"
                     /protein_id="HET2612067.1"
                     /translation="MSHIIELPEMLANQIAAGEVIERPASVVKELVENAIDAGSSQII
                     IEIEEAGLKKIQITDNGYGIAHDEVELALRRHATSKIKNQADLFRIRTLGFRGEALPS
                     IASVSVLTLLTAVDGASHGTKLVARGGEVEEVIPATSPVGTKVCVEDLFFNTPARLKY
                     MKSQQAELSHIIDIVNRLGLAHPEISFSLISDGKEMTRTAGTGQLRQAIAGIYGLVSA
                     KKMIEIENSDLDFEISGFVSLPELTRANRNYISLFINGRYIKNFLLNRAILDGFGSKL
                     MVGRFPLAVIHIHIDPYLADVNVHPTKQEVRISKEKELMTLVSEAIANSLKEQTLIPD
                     ALENLAKSTVRNREKVEQTILPLKENTLYYEKTEPSRPSQTEVADYQVELTDEGQDLT
                     LFAKETLDRLTKPAKLHFAERKPANYDQLDHPELDLASIDKAYDKLEREEASSFPELE
                     FFGQMHGTYLFAQGRDGLYIIDQHAAQERVKYEEYRESIGNVDQSQQQLLVPYIFEFP
                     ADDALRLKERMPLLEEVGVFLAEYGENQFILREHPIWMAEEEIESGIYEMCDMLLLTK
                     EVSIKKYRAELAIMMSCKRSIKANHRIDDHSARQLLYQLSQCDNPYNCPHGRPVLVHF
                     TKSDMEKMFRRIQENHTSLRELGKY"
     gene            complement(10519..10986)
                     /locus_tag="VQ543_001349"
     CDS             complement(10519..10986)
                     /locus_tag="VQ543_001349"
                     /EC_number="2.5.1.78"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001099498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6,7-dimethyl-8-ribityllumazine synthase"
                     /protein_id="HET2612068.1"
                     /translation="MNTYEGNLVANNIKIGIVVARFNEFITSKLLSGALDNLKRENVN
                     EKDIEVAWVPGAFEIPLIASKMAKSKKYDAIICLGAVIRGNTSHYDYVCSEVSKGIAQ
                     ISLNSEIPVMFGVLTTDTIEQAIERAGTKAGNKGSECAQGAIEMVNLIRTLDA"
     gene            complement(10987..12192)
                     /locus_tag="VQ543_001350"
     CDS             complement(10987..12192)
                     /locus_tag="VQ543_001350"
                     /EC_number="3.5.4.25"
                     /EC_number="4.1.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP
                     cyclohydrolase II"
                     /protein_id="HET2612069.1"
                     /translation="MEYRKIQEALEALQKGRLVLVIDDKDRENEGDLICSAQAATTEN
                     VNFMATYAKGLICMPMSESLANQLMLSPMVENNTDNHKTAFTVSIDYKETTTGISAEE
                     RGLTARMCVAEDITPSDFRRPGHMFPLIAKKGGVLERNGHTEATVDLLKLAGLKECGL
                     CCEIMNHDGKMMRTDDLIQFSKKHNIPLITIKELQEYRKVYDQLVERVSTVNMPTRYG
                     NFKAISYIDKLNGEHHLALIMGNIEDEANVLCRVHSECLTGDVLGSLRCDCGQQFDKA
                     MKMIVENGSGVLLYLRQEGRGIGLINKLKAYHLQDQGMDTLDANLALGFEGDLREYHI
                     GAQMLKDLGLQSLHLLTNNPDKVEQLEKYGITISSRISIEIEANPYDSFYLETKKNRM
                     GHILNMEEK"
     gene            complement(12212..12847)
                     /gene="ribE"
                     /locus_tag="VQ543_001351"
     CDS             complement(12212..12847)
                     /gene="ribE"
                     /locus_tag="VQ543_001351"
                     /EC_number="2.5.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000493842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="riboflavin synthase"
                     /protein_id="HET2612070.1"
                     /translation="MFTGIIEEIGKVERIQKDSRNCKLSIKASKILTDIHLGDSIAVN
                     GICLTVTHFNHQSFTVDVMNETWSRTALTLLKHGSEVNLERALSVNGRLGGHVVTGHI
                     DGTGKISSIKKDDNAVWYQINTQKEILDLIVEKGSITIDGISLTVAKVSKVNFSVSVI
                     PHTLEQTILKSKQVGSTVNLENDILGKYVQKLMDNSPKSEISKELLYQNGF"
     gene            complement(12832..13932)
                     /gene="ribD"
                     /locus_tag="VQ543_001352"
     CDS             complement(12832..13932)
                     /gene="ribD"
                     /locus_tag="VQ543_001352"
                     /EC_number="1.1.1.193"
                     /EC_number="3.5.4.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     diaminohydroxyphosphoribosylaminopyrimidine
                     deaminase/5-amino-6-(5-phosphoribosylamino)uracil
                     reductase RibD"
                     /protein_id="HET2612071.1"
                     /translation="MSDSKYMKLAIKLAQKGAGYVNPNPMVGAVIVKDNHIIGQGYHE
                     FFGGPHAERNALKNCRESPVGATLYVTLEPCCHFGKTPPCIDAIIDSGITRVVIGSLD
                     CNPIVSGKGVKILEENNLQVTVGILENECLNLIKSFRKYITQHVPYVFMKYAMSMDGK
                     IATKTNQSKWITEEEARKHVHQLRHHVSAIMVGVNTVIQDDPLLTCRLEEGKNPIRII
                     CDTHLRTPLTSKIVKTANDIKTYIATSSEDKNKMKLYQNHGCEILSIKKKGNHIDLSS
                     LMQHLGNMQIDSLVLEGGSLMNWSALEQQIVDELKIYIAPKIFGGSAKFPVGGEGISL
                     PNDAIRLKPYAFSQIGNDYLIESEVIYPCSQE"
     regulatory      complement(14067..14181)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            14338..14931
                     /gene="ruvA"
                     /locus_tag="VQ543_001353"
     CDS             14338..14931
                     /gene="ruvA"
                     /locus_tag="VQ543_001353"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000271492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration protein RuvA"
                     /protein_id="HET2612072.1"
                     /translation="MYAYLKGIITKITAKYIVLETNGIGYILHVANPYAYSGQVNQEA
                     QIYVHQVVREDAHLLYGFRSEDEKKLFLSLISVSGIGPVSALAIIAADDNAGLVQAIE
                     TKNITYLTKFPKIGKKTAQQMVLDLEGKVVVAGDGLPAKVAVQASAENQELEEAMEAM
                     LALGYKATELKKIKKFFEGTTDTAENYIKSALKMLVK"
     gene            14941..15504
                     /locus_tag="VQ543_001354"
     CDS             14941..15504
                     /locus_tag="VQ543_001354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase I"
                     /protein_id="HET2612073.1"
                     /translation="MTKRCSWVKMTNPLYIAYHDEEWGQPLHDDQALFELLCMETYQA
                     GLSWETVLNKRQAFREAFHSYQIHSVAEMTDTELEAMLENPAIIRNRAKIFATRANAQ
                     AFLQLQAEYGSFDAYLWSFVEGKTVVNDVPDYRQAPAKTPLSEKLAKDLKKRDFKFTG
                     PVAVLSFLQAAGLVDDHENDCEWKGLK"
     gene            15501..16178
                     /locus_tag="VQ543_001355"
     CDS             15501..16178
                     /locus_tag="VQ543_001355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000987430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET2612074.1"
                     /translation="MMSNKNKGILIFAILYTVLFVFDGVKLLASLMPSAIANYLVYVV
                     LALYGSFLFKDRLIQQWKEIRKTKRKFFFGVLTGWLFLILMTVVFEFVSEMLKQFVGL
                     VGQGLNQSNIQSTFQEQPLLIAVFACVIGPLVEELFFRQVLLHYLQERLPGLLSIILV
                     GLVFALTHMHSLALSEWIGAVGYLGGGLAFSIIYVKEKENIYYPLLVHMLSNSLSLII
                     LAISIVK"
     gene            complement(16319..17350)
                     /locus_tag="VQ543_001356"
     CDS             complement(16319..17350)
                     /locus_tag="VQ543_001356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000255096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LD-carboxypeptidase"
                     /protein_id="HET2612075.1"
                     /translation="MVSTIGIVSLSSGIIGEDFVKHEVDLGIQRLKDLGLNPIFLPHS
                     LKGLDFIKDHPEARAEDLIHAFSDDSIDMILCAIGGDDTYRLLPYLFENDQLQKVIKQ
                     KIFLGFSDTTMNHLMLHKLGIKTFYGQSFLADICELDKEMLAYSLHYFKELIETGRIS
                     EIRPSDVWYEERTDFSPTALGTPRVSHTNTGFDLLQGRALFEGKILGGCLESLYDIFD
                     NSRYADSTELCQKYKLFPDLSDWEGKILLLETSEEKPKPEDFKKMLLTLKDTGIFAVI
                     NGLLVGKPMDETFHDDYKEALLDIIDSNIPIVYNLNAGHATPRAIVPFGVHAHVDAQE
                     QVIRFDYNK"
     gene            complement(17605..18288)
                     /locus_tag="VQ543_001357"
     CDS             complement(17605..18288)
                     /locus_tag="VQ543_001357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1129 domain-containing protein"
                     /protein_id="HET2612076.1"
                     /translation="MSQIDLQKLTKKNQEFVHIATQQFIKDGKTDAEIQTIFEEVIPQ
                     ILEEQSKGTTARSLYGAPTHWAHSFTVKEQYEKEHPKENDDPKLMIMDSALFITSLFA
                     LVSALTTFFAADQAFGYGLITLLLVGLVGGFAFYLMYYFVYQYYGPDMDRSQRPPFWK
                     SVLVILASVFLWLLVFFATSFLPASLNPVLDPLPLAIIGAALLALRFYLKKRLNIRSA
                     SAGPTRYQE"
     gene            complement(18300..19244)
                     /locus_tag="VQ543_001358"
     CDS             complement(18300..19244)
                     /locus_tag="VQ543_001358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HET2612077.1"
                     /translation="MKQVFLSTTTEFKEIDTLEPGTWINLVNPTQNESLEIANTFDID
                     IADLRAPLDAEEMSRITIEDEYTLIIVDVPVTEERNNRTYYVTIPLGIIITEETIITT
                     CLEPLPVLDVFINRRLRNFYTFMRSRFIFQILYRNAELYLTALRSIDRKSEQIESQLH
                     QSTRNEELIELMELEKTIVYFKASLKTNERVIKKLTSSTSNIKKYLEDEDLLEDTLIE
                     TQQAIEMADIYGNVLHSMTETFASIISNNQNNIMKTLALVTIVMSIPTMVFSAYGMNF
                     KDNEIPLNGEPNAFWLIVFIAFAMSVSLTLYLIHKKWF"
     gene            19376..22207
                     /gene="uvrA"
                     /locus_tag="VQ543_001359"
     CDS             19376..22207
                     /gene="uvrA"
                     /locus_tag="VQ543_001359"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HET2612078.1"
                     /translation="MQDKIVIHGARAHNLKNIDVEIPRDKLVVVTGLSGSGKSSLAFD
                     TLYAEGQRRYVESLSAYARQFLGNMEKPDVDAIDGLSPAISIDQKTTSKNPRSTVGTT
                     TEINDYLRLLYARVGTPYCINGHGAIKASSVEQIVDKVLELPERQRLQILSPVIRKKK
                     GQHKSVIEKVQKDGYVRVRVDGEVYDVTEVPELSKSKQHNIDVVVDRIVIKEGIRSRL
                     FDSIEAALRIAEGYVIIDTMDNSELLFSEHYACPVCGFTVPELEPRLFSFNAPFGSCS
                     ECDGLGIKLEVDTDLVVPNASKTLHEGALAPWNPISSNYYPNMLEQAMTAFGVAMDKP
                     FEDLSEEDKNLILYGSDGKKFHFHYENEFGGVRDIDIPFEGVINNIKRRYHETNSDYT
                     RTQMRLYMNELTCGTCHGYRLNDQALSVRVGGEQGPHIGEISDLSIADHLDLVSQLTL
                     SENEAIIARPILKEIKDRLTFLNNVGLNYLTLSRSAGTLSGGESQRIRLATQIGSNLS
                     GVLYILDEPSIGLHQRDNDRLIASLKKMRDLGNTLIVVEHDEDTMREADYLIDVGPGA
                     GVFGGEIVAAGTPKQVARNSKSITGQYLSGKRVIPVPEERRVGNGRFIEVIGARENNL
                     QNVTARFPLGKFIAVTGVSGSGKSTLINSILKKAIAQKLNRNSDKPGKFKTITGIEHV
                     DRLIDIDQSPIGRTPRSNPATYTGVFDDIRDLFAQTNEAKIRGYKKGRFSFNVKGGRC
                     EACSGDGIIKIEMHFLPDVYVACEVCHGTRYNSETLEVHYKEKNISQVLDMTVNDAVE
                     FFQHIPKIQRKLQTIKDVGLGYVTLGQPATTLSGGEAQRMKLASELHKRSTGKSFYIL
                     DEPTTGLHTEDIARLLKVLARFVDDGNTVLVIEHNLDVIKTADHIIDLGPEGGVGGGT
                     IIVTGTPEEVAANEASYTGHYLKGKLHHE"
     gene            22200..23261
                     /locus_tag="VQ543_001360"
     CDS             22200..23261
                     /locus_tag="VQ543_001360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HET2612079.1"
                     /translation="MNKRVQAFLAKMQEKELDGVIINNLKNVYYLTGFWGSNGTVFIS
                     RDRQVLVTDSRYIIAAKQETSGFEIVADRDELAVIAGIVKDMGLTRIGFEDEISVSYY
                     HRMQAAFAGLNLLPQTQFVEGLRMIKDEAEIAAIRKACSISDQAFRDALDFIKPGKTE
                     IEIANFLDFRMRELGASGLSFDTILASGINSSKPHAHPMHKPVELGEAITMDFGCLYD
                     HYVSDMTRTIYLGHVSDEQAEIYNTVLKANQALIDQAKAGLGFRDFDKIPRDIIIEAG
                     YGDYFTHGIGHGIGLDIHEEPYFSQTSTETIKTGMALTDEPGIYIEGKYGVRIEDDIL
                     ITETGCELLTLAPKELIVI"
BASE COUNT         7035 a         4105 c         4754 g         7418 t
ORIGIN      
        1 agatctgaaa taactgttat gatatagagg attgaaacta gaatagtaca cctctgcttc
       61 taaaacattg ttagaaatcg atttgactgt cctgatcgat ttatcctgtt cttatttcat
      121 ttcactatag taaggtgcag caggataaag aaaaaccgag aagtttcttt ctcggatttg
      181 cttattatga ggttcctatt ttctatgctc caagagttga ttgatgtgat ctactttttt
      241 agcctctctt ttatagagaa tagcccagat gatgagatag acaatcgcaa actcgataat
      301 gagctggagg tagaaaatcc agtggaaagg gaaccaacca gcaagagttg ctagtgggac
      361 aaagccagcc agcataagga agaaatgagt cagagtggca cgaagcatgc tccagtcacg
      421 gctgaataag cgattgccaa agttgaagag cataccaatg gctgcccaga taagtgtgca
      481 gtagagcaag accaaggcac cgtgaacctg atgctgatcc atcacttggc cgatgagaga
      541 gtagggattt agtggtgcgt aggtatttgg tgcataaatg agtgaaaaga ggatagagag
      601 gatgaggccg ataagaacac cggcagctgc atcgtgaaat acttgttttt tcatagttct
      661 aatttctcct tgatggtttt tagataacgg cgtgaagagt aggtgaagct ttcgtttttc
      721 aagaaaattt ctaccagacc gtttggcgtg agcttgaggt gagagatgga atcgatattg
      781 atgatttctg attgggaaat ttggataaaa ttggttggca agagtttaag aacctgatag
      841 agtcgcaaat caatgctgta ggtctgactc gcggtttctg ctagaacctt ccgattctcg
      901 atatagaagc gctgaatctt gccaatctca actagataga cctgatcatc gattttccct
      961 ttgatttttt ctctttggtc cagattttct gcgaactcga tgactttctg aactttatct
     1021 gtcggctgag gtgcttggac aatcagcttt tcctcctcgt aagtctcact aatctgtaat
     1081 tctactttca taaatttctc tccttgtttt tcatacaaaa ttaatctcac ttcttgtaca
     1141 cctttattaa tactcttcaa aaatctcttc aaaccacgtc agcgtcgtct tgccgtagga
     1201 tagttgttga ctttgtcagt tttatctaca acctcaaaac agtgttttga gctgtctgcg
     1261 cctagctttc tagtttgctc tttgattttt attgagtata ccactatttt actccctctg
     1321 gcaaggtact ttgtctatgt ggagggattg ggctcctatg tggtggagct tttctgttct
     1381 ttctgaaata tggtataata gcactaatca atttctagga aaatagatac agaaaggggc
     1441 tgaaagaact aggggaacag ttgtaattag aaggtgatag gtatgaaaag tggcgttgaa
     1501 gctggataag tttataaaga gtttgaatga agaaatgaaa agtaaataag ttgatgatga
     1561 attgcaaaaa tagattttat atacaatttg tatctttcaa atcattgatt tgaattttag
     1621 atttaatcat gttacaatta aaaatgaaat caaatagaag aggaagatgc aaacgtgggc
     1681 acactattag caacaagatt aaaaaataga cgaaaagaat taaaaatgtc tcagcgagaa
     1741 ctagctgaag gtatctgtaa acaggggcaa atcagtcgat tagagagcgg agagtttact
     1801 cctggagcag atttcttgca tgcccttgct aagaagttaa aagtcagtat ggattatttt
     1861 tttgatgagc aggttgtaga gaaagttgag gagttatcag aatttaagaa attagcacag
     1921 acatttatta caaatcgcaa ttatgagtct ttgaaatata tatatgaatt ggagaatgta
     1981 aaagctcacc gcctatcttt agcagataaa atctacatgg aatggataaa atctctgata
     2041 gatttttatt tttacggaca gaaagaagat gcgattgtac gattagaggg ggtattatca
     2101 cagttaagtg tatctgattt gaactatctc caagtttcaa acaccctatt caatttttat
     2161 tatgatattg gagatttagg tcgtttcaat aaaattcgtg aaaaactaga gtatcaagta
     2221 aatcacctca atttgagtac aatcgaagag ttagaactat ctattaagtt taactacaac
     2281 gtttgtcgtt atctatggtt acagaaaaat attgaagaag ctattactaa aattacagct
     2341 actataaaac aatgtaaggc ttacagaacg aattatcttt tggctgattt gtacttattg
     2401 atgggaaatg taagtgaaaa tttttcttct aaaagttcgg tgaaagaata ttttgagacg
     2461 gcatattttc tatacaaact tgaggagaac atgtcaatga ctctgaaagt tgagcattac
     2521 attgcagata taacagaata atgaatacgg tgttcaagtg agcatcgttt ttcaaaccta
     2581 gttcagatac aaaaaagtat caaataaaaa aaaataaaaa aacattataa aaacaattga
     2641 caagctaatt ttgaagtgat aaaataaatg caagaaaaca aaaggagagg tatatgagaa
     2701 gtttgtttaa gaaaatagtt gctgtattag ttattggctt aattctgtta ggaattgcga
     2761 gaacacctca agttcataag atggctagag ggattgatcc tggtcctgcg aattttattt
     2821 agaaatcaat ttctactaat tgagtactaa ttgagtatta atgggtaaaa agattgtatg
     2881 gataagaaaa atttacttgt attggttact ggttcggtag gtgccagtaa tgtagataca
     2941 tacttatatt atataaaaaa attctataat gttaaagtga tactttctga aaattctaaa
     3001 aaatttataa gtaaggaatt aattagttat ttttgtgata aagtttatga tgaaatattt
     3061 gttgaagagg tagttccgca cgtttttctg ccatatgaat ctgacttact tcttatttta
     3121 ccagctacgg caaatgtgat tggcaaaatt gctaatggta ttgctgatga tttagttaca
     3181 gcaactgttt taaactttaa taaaaaaata attttttgtc ccaatatgaa ctctactatg
     3241 tgggacaatc acatagttca aagaaatgta tcaattctaa aggagttggg acatatattt
     3301 ttatttgagt ctaaaaaaac atatgaggta ggattgcgta aagcaataga ttcaacatgt
     3361 tcaatgttac aaccacagtc gttagtaaaa gaacttatca aattagaaaa tattgtcctt
     3421 gaagagggac attaaaaact actgagaata ttaaggaggg gaaaaaatgg aaaattcatc
     3481 aatcgatgta gatatgctgt tggaagaatt gacacaagaa gcaatggtcg ttgttgctgt
     3541 tgataaggac tgttaattta aacttatggc aatatatgaa aggttactgg atgttttaaa
     3601 ttatgcaggc agtagccttt tattatatac aaatggataa agtaaggata atacaatgat
     3661 taataaaaaa atacaacaag ttgttttgga atcattacag aattttttga atgggaactt
     3721 catttcgcct tgtgtagtct atgattttgg cttgctggaa actgtacttg atgaatttaa
     3781 aaatcaaatt cctgtaacat tcaattacca acttttttat gccgttaaag caaattcaaa
     3841 tgagaagata cttgaattct tagtagataa aattgatgga gttgatgtgg cgtcattatc
     3901 tgaattagat gtggctaaaa aatttttccc accaactcaa atttctgtta atggtcccgc
     3961 attttcttat gaaactttat ataatctgat taaaaaacaa tataaagttg atattaactt
     4021 tttggaacat cttcaacaat tttccccaaa agaatctgtt ggaataagag taacggagcc
     4081 agatgaactt aataatcgta tgagtcgatt tggaataaat atttgcagtg ataattggac
     4141 tagtaattta caaaatcctt taattacacg actgcatttt cattttggag aaaaagatga
     4201 taaatttatt gttaagttag ataaaatatt atttaagtta caagaaatta ataaacttag
     4261 agaggttaga gaaataaatc ttggaggcgg ttttatgaaa ttatttatgg aaaatcgttt
     4321 gaaagaattt tttctatcac ttatggaaat ctataaaaag tacgatattg atagtactgt
     4381 gactacaata atagaaccag gtagtgcaat tacttcattt tctgcctata tgattactag
     4441 cccagttaat gttagtgagg tgaatgagca gcaggttatc acgttagaca catcaatata
     4501 caccaataca ttatggtttg ttccgcatat tattacaacg ttaaattcaa gtagtaaaga
     4561 gcgttatagt actattctct atggtaatac ctgttatgaa catgacaagt ataaaatgaa
     4621 agtttcgctt ccaaggttaa ctcaaaatag cagtatagtg ttttttcctg taggagctta
     4681 tataaaaagc aatcattcaa atttacatcg taatgatttt atgcgggagg tatatttgtg
     4741 gacaaaaaac ttgacatatt agataaagtt aaggaatatt taggaaataa aactactcaa
     4801 attctggata atcaatataa agaatttttg aaacttaatg atataaggcg agcgtttggt
     4861 atttcagaaa aagtattaaa caattctttt aattttacga gtaaagaatt taatgattta
     4921 attaataacg aaaattattt attcgaatat gcatgtagaa ttagagagga atggagaaaa
     4981 aaatgcttta atcattctta tcgttttcta tgctcaccta taattacaga tgattttctt
     5041 aacacgaaga cattgagaag tagccaaatt gaatataaat atgagcgata tttatcgaaa
     5101 agttcgatag gcgatagagc ggttgatggc tttgtttcct tcaatacttt aacagctaat
     5161 ggtatgtctg ctattaaact atgtcttgag atattaaact ctattttctt caagaagaag
     5221 attgatttat tatattcaac cggatattat gaaacaagat ttttattaaa taatcttgct
     5281 aaatcaggta ttagttgcta tgaggtaagt aattgtgaat tggataaaga taaattttat
     5341 aatgtattca tgatggaacc caatcgagcc gatttaacat tacaaaaaac tgatttcaag
     5401 atagtagaat attttgttaa gtataaaaat aattcaataa aagtcgttat tttagatatt
     5461 tcatatcaag gttctaattt taaattagta gaatttttag agaaatttaa atttgcgaat
     5521 gtaattattt ttgtggtacg atctttgata aaattagatc aaatgggatt agaattgaca
     5581 aatgggggaa taatagaagt gtttattcct aatcatttga gaaagttgaa aaattttatt
     5641 gaagaggaat tcaataaatt tagaaattct cacggagcta atctaagcct ctatgaatac
     5701 tgtttgcttg ataattcttt aaccttaaaa aatgattgga actattctga tttagttatg
     5761 aaatttacga gtaattttta tgctgatata aaagacttgt tcatggaaaa ttctgatatt
     5821 gaaatcatcc atgaagaggg agtacctttt gtatttttag atttaatagg tgaaggtaaa
     5881 aaagaatatg aaatgttttt tcaatggtta aacttctttt acaaacagct tggaatcaca
     5941 ttgtatgcta gaaatagttt tgggtttcgg aatctaacag tagagtattt tggaattatt
     6001 gggacagaaa gatatatatt taagatttgt ccaggtgttt ataaagggtt aagttattat
     6061 ttgatgaaat ttttattaaa atctttttca aatgaatatt taaaaactac tgatgaggtt
     6121 aatagatgaa aaatttgata aagttgctaa taattagatt gattgttaac ttagcagaca
     6181 gtgtatttta tatagtagca ttgtggcacg ttagcaataa ttattcttcg agcatgttct
     6241 taggaatatt tattgcagta aattatctac cggatttgtt actaatcttt tttggaccag
     6301 ttattgacag agtaaatccg caaaaaattc ttataatatc aattttggtt caattagcag
     6361 tggctgtaat atttttatta ttattaaacc aaatatcatt ttgggtgata atgagtctag
     6421 tgtttatttc agtaatggct agctccataa gttacgtgat agaagatgtg ttgattcctc
     6481 aagtggtaga atatgataag attgtatttg caaattctct ttttagtatt tcgtataaag
     6541 tattagattc tatttttaat tcattcgcat catttttaca ggtggcagta ggatttattt
     6601 tattggttaa gatagatata ggcatatttt tacttgctct atttatattg ttgttgttaa
     6661 aatttagaac tagcaatgcg aatatagaaa acttctcttt caaatattac aagagagaag
     6721 tgttgcaagg tacaaagttt attttaaata ataaattatt atttaaaacc agtatttctt
     6781 taacgcttat aaactttttt tattcatttc agacagtagt tgtaccgatt ttttctattc
     6841 gatattttga tggtccgatt ttttatggta tttttttaac tattgctggt ttgggtggta
     6901 tattgggaaa tatgctagcg ccaatcgtaa taaaatattt aaaatcgaat caaattgttg
     6961 gtgtatttct ttttttgaac ggctcaagtt ggttagtagc aattgttata aaagactata
     7021 ctttatcact tattttattt ttcgtttgtt ttatgtctaa aggagtcttc aatattattt
     7081 ttaattcgtt gtaccaacaa atacctccac atcaacttct tggtagggta aatactacca
     7141 ttgattctat tatttctttt ggaatgccaa ttggtagttt agttgcagga acgcttattg
     7201 atttgaatat tgaattagtg ttaattgcta ttagcatacc ttattttttg ttttcttata
     7261 ttttttatac ggataatgga ttgaaagaat ttagtatata ttagaaatgt ttatgttcat
     7321 tcaaaagcat aatgactata actgaaaaag aaaagtgata tctttaaggt tgttcttctt
     7381 ggtggtgaga ttcgtgagac aacccaagct tttgtcggaa agattaccaa tgctttgatg
     7441 gataggatgt actttagcaa gatgttttta gtggtaacgg tatcgtggat ggacgtgtaa
     7501 taacctcttc tttcgaggag tattttacta aaaaactagc cttggagcgt tccccagaaa
     7561 cggacttact cattgactct tcaaagattt ggggagaaga ttttgcttca tctgttcctt
     7621 gaaaaaagtc acagcagtca tcacagacga tagtactgaa caaaactatg aagagttaga
     7681 aatttatacg caggtgattg tataaaggat ctggaaatag ataagaagtt gattagtatt
     7741 gacctaggtg gtacaaatat taagattact gttctttcaa atgacggtga gattgaaact
     7801 ttgtggagta ttacaacaga tacaagtgag aaaggttctc aaattatatc ggacatcatc
     7861 agttctatta aaaataaatt gaccgaacgg aatattcctg atagcgacct tcttggaatc
     7921 ggtatgggaa gttgctcatc atactttcct tgtaaatcat aggggctata aactctccgt
     7981 ctacttgtcc tgcaacaatt gaagtctgct caaaacgccg tccgctaatc ttttcataga
     8041 ctttctccct tttaggagcc tagctttcta gtttgttctt tgatttttat tgagtatacc
     8101 actattttac tccctctggc aagggacttt gtctatgtgg agggattggg ctcctatgtg
     8161 gtggagcttt tctgttcttt ctgaaatatg gtataatagc actaatcaat ttctaggaaa
     8221 atagatacgg aaaggggctg aaagatgtct catattattg aattgccaga gatgctggca
     8281 aaccaaatcg cagctggaga ggtcattgaa cgtcctgcca gcgtggtcaa agaattggta
     8341 gaaaatgcca ttgacgcggg ctctagtcag attatcattg agattgagga agctggtctc
     8401 aagaaaatcc aaatcacaga taacggttat ggaattgccc acgatgaggt ggagttggcc
     8461 ctgcgtcgcc atgcgaccag taagataaaa aatcaagcag atctctttcg gattcggacg
     8521 cttggttttc gtggtgaagc cttgccttct attgcgtctg ttagtgtctt gactctgtta
     8581 acggcggtgg atggtgctag tcatggaacc aagttagtcg cgcgtggggg tgaagttgag
     8641 gaagtcatcc cagcgactag tcctgtggga accaaggttt gtgtggagga tctctttttc
     8701 aacacgcctg cccgtctcaa gtatatgaag agccagcaag cggagttgtc tcatatcatt
     8761 gatattgtca accgtctggg cttggcccat cctgagattt cttttagctt gattagtgat
     8821 ggcaaggaaa tgacgcggac agcagggact ggtcaattgc gccaagcaat cgcagggatt
     8881 tacggtttgg tcagtgccaa gaagatgatt gaaattgaga actctgacct agatttcgaa
     8941 atttcaggtt ttgtgtcctt gcctgagttg actcgggcta accgcaatta tatcagcctc
     9001 ttcatcaatg gtcgttatat caagaacttc ctgctcaatc gtgctatttt ggatggtttc
     9061 ggaagcaagc ttatggttgg acgttttcca ctggctgtca ttcacatcca tatcgaccct
     9121 tatctagcgg atgtcaatgt gcatccaact aagcaagagg tgcggatttc caaggaaaaa
     9181 gaactgatga ccctggtttc agaagctatt gcaaatagtc tcaaggaaca aaccttgatt
     9241 ccagatgcct tggaaaatct tgccaaatcg actgtgcgca atcgtgagaa ggtggagcaa
     9301 actattctcc cactcaaaga aaatacgctc tactatgaga aaactgagcc gtcaagacct
     9361 agtcaaactg aagtagctga ttatcaggta gaattgactg atgaagggca ggatttgacc
     9421 ctgtttgcca aggaaacctt ggaccgattg accaagccag caaaactgca ttttgcagag
     9481 agaaagcctg ctaactacga ccagctagac catccagagt tagatcttgc tagcatcgat
     9541 aaggcttatg acaaactgga gcgagaagaa gcatccagct tcccagagtt ggagtttttc
     9601 ggacaaatgc acgggactta tctctttgcc caagggcgag atggacttta catcatagat
     9661 cagcacgctg ctcaggaacg ggtcaagtac gaggagtacc gtgaaagcat tggcaatgtt
     9721 gaccagagcc agcagcaact cctagtgccc tatatctttg aatttcctgc ggatgatgcc
     9781 ctgcgtctca aggaaagaat gcctctctta gaggaagtgg gcgtctttct agcagagtac
     9841 ggagaaaatc aatttattct acgtgaacat cctatttgga tggcagaaga agagattgaa
     9901 tcaggcatct atgagatgtg cgacatgctc cttttgacca aggaagtttc tatcaagaaa
     9961 taccgagcag agctggctat catgatgtct tgcaagcgat ctatcaaggc caatcatcgt
    10021 attgatgatc attcagctag acaactcctc tatcagcttt ctcaatgtga caatccctat
    10081 aactgtcctc acggacgtcc tgttttggtg cattttacca agtcggatat ggaaaagatg
    10141 ttccgacgta ttcaggaaaa tcacaccagt ctccgtgagt tggggaaata ttaaaagtat
    10201 aaaaaagtct gggaaaaatt ttcaaaatca gaaaaacgca taaaatcagg tgttcaaaaa
    10261 ccttgatttt atgcgtttta tcatggaaat agttacttca tgttttccta attcttttcg
    10321 aaactctttt taaaccacgt cagttttatc agtaatctca aaacagtgtt ttgagctaat
    10381 tttgccagtt ttatctgtaa catcgaagtt gtgtttgacc actctgcgac tggtttccta
    10441 gtttgctcta tgattttcac agagtattaa attgcgattt tgccaagttt ctttattcgt
    10501 ctaaaagtag agtctgttct atgcgtctaa tgtacgaatt aggttgacca tttcaatagc
    10561 tccttgtgca cactcagaac ccttatttcc tgctttggta ccagctcgtt ctatggcttg
    10621 ttcaattgta tctgtcgtta gcacaccaaa cataacagga atttcgctat ttaaactgat
    10681 ttgggcgatt cccttagata cctcgctaca tacataatca taatgacttg tattccctct
    10741 aatgacagct cccaagcaga taattgcatc atatttttta ctttttgcca tttttgatgc
    10801 aatcagtggt atttcaaaag ctcctggaac ccaggctacc tctatatctt tctcgtttac
    10861 attctctctt ttgagattat ctagtgctcc agataataat tttgaagtta taaattcatt
    10921 aaatctcgct acaacaatac ctattttaat attgtttgct actaaattac cttcataagt
    10981 gttcatttat ttttcctcca tatttaaaat gtgacccatt cgatttttct ttgtttctaa
    11041 ataaaaacta tcgtaaggat tggcttctat ttcgattgat attctactgg aaatggtaat
    11101 tccatatttt tctaactgtt caaccttgtc aggattattt gtcagtaaat gaagtgactg
    11161 aagtcccaga tctttaagca tttgtgctcc aatatgatat tctcttaaat caccttcaaa
    11221 gcctaatgca agattggcat caagcgtatc catgccttga tcttgtaaat gataggcttt
    11281 taatttattg ataagtccaa ttcctcgtcc ctcctgtcgc aagtaaagta agacacccga
    11341 accattctca acaatcattt tcatagcttt atcgaattgc tgtccacaat cgcaacgtaa
    11401 agagcctaaa acatctcctg ttaaacattc ggagtggacc cgacataata cattggcttc
    11461 atcctctata tttcccataa taagagcaag atgatgttcc ccatttagtt tatctatata
    11521 gctaattgct ttgaaattac cgtatctagt aggcatattg acagttgaaa ctcgttctac
    11581 cagctgatca tatacttttc tatattcttg taattctttg atggtaatta gtggaatgtt
    11641 gtgtttcttc gagaactgaa ttaaatcatc tgttctcatc attttgccat catgattcat
    11701 tatttcacaa cataggccac actcttttag tccagctaat tttaataaat caacagttgc
    11761 ttctgtgtgt ccatttcttt ctagaacacc accttttttt gcaattaaag gaaacatgtg
    11821 tcctggcctg cgaaaatcag agggtgttat atcttcagct acacacatac gtgcggtcag
    11881 tcctctctcc tcggcagaaa tacctgtggt cgtttcttta taatcaattg aaactgtaaa
    11941 agcagtctta tgattatctg tattgttttc aaccataggt gaaagcatta attgattagc
    12001 taaactttcg ctcataggca tacaaattaa tcctttggca taagtagcca taaaattaac
    12061 attttctgtt gtagctgctt gtgcagaaca aattaagtct ccttcatttt ctctatcctt
    12121 gtcgtctata acaagaacaa gtcgtccctt ctgcaatgct tctaatgctt cttgtatttt
    12181 tcgatattcc attgactgat tatcctttct gctaaaatcc attttgatat aatagttcct
    12241 tagatatttc tgattttgga gagttatcca tcagtttttg cacatattta cctaagatat
    12301 cattttcaag atttactgta ctcccgactt gtttactctt aagaatggtt tgttccaagg
    12361 tatgagggat aacagatact gaaaagttta ctttggagac tttagcgaca gtcagactaa
    12421 tgccgtcaat tgtaatagat cctttttcaa ctattaaatc taaaatttct ttttgtgtgt
    12481 tgatttgata ccatacagca ttatcatctt tttttattga cgagattttt cctgtaccat
    12541 caatgtgtcc tgtaacgacg tgacccccaa gtcgaccgtt gacagataag gctctttcta
    12601 gattcacctc acttccatgt tttaatagag taagagctgt tcgactccat gtttcattca
    12661 ttacatcaac tgtaaaggat tgatgattga aatgagtaac tgtaagacag ataccattta
    12721 ctgctatact atcgcctaaa tggatatccg ttaatatttt tgaggcttta attgatagtt
    12781 tacaattacg agagtctttc tgtattcttt caacttttcc gatttcttca attattcctg
    12841 tgaacatgga taaatcactt cactttctat gagatagtca tttcctattt gagaaaaagc
    12901 ataaggtttc aatctaatag cgtcatttgg caaagaaatg ccttcacctc cgacaggaaa
    12961 cttggcactg cctccaaaaa tttttggtgc aatatatatt ttcagctcat caacaatttg
    13021 ttgttccaaa gcactccaat tcattagact gcccccttct agaactaggc tatcaatctg
    13081 catgtttcct agatgttgca ttaaactcga taagtctata tgattgcctt ttttctttat
    13141 ggaaagtatt tcacagccat gattttgata tagcttcatt ttatttttgt cttcagagga
    13201 agtggcaatg taagttttaa tatcatttgc tgtttttacg attttagagg taagaggagt
    13261 tcgtaaatgt gtatcgcata tgatacggat aggatttttc ccttcctcca atctacatgt
    13321 cagcaaagga tcgtcttgaa taacagtatt gactcccacc ataattgcac taacatggtg
    13381 tcgtaactga tgcacatgct ttcttgcttc ttcttcagta atccatttgg attgatttgt
    13441 tttagtggct atttttccat ccattgacat tgcatatttc ataaaaacat agggtacatg
    13501 ctgggtaata tactttctaa aactttttat taagttaaga cactcatttt ctaaaattcc
    13561 aacagtaact tgaagattat tttcctcaag tatctttact ccttttccag atacaatagg
    13621 attacagtct aggcttccaa tgactactct tgtaatacca ctatcgatta tagcatctat
    13681 acagggaggt gttttcccga agtgacaaca gggttcaagt gttacataaa gcgtcgctcc
    13741 gacaggggat tctctacagt ttttaagagc atttctctca gcatgtgggc caccaaaaaa
    13801 ctcatgataa ccttgtccga tgatgtgatt atcttttaca ataactgcgc cgaccatagg
    13861 attgggattg acgtaaccag cccctttttg tgccagtttt attgctaatt tcatatattt
    13921 tgaatcgctc atctcactac ctccaaaaaa aatatacctt gaatagggga ctactcaagg
    13981 catacaaaag aaaacttatg cgattaacaa aaatactctg aaatgacaag taatcatttc
    14041 agagcacgca aaaagcacaa atatactttt atcttctttc atccagacta tactgtcggc
    14101 tttggaattt caccaaatca tgcctttcgg ctcgtgggct ataccaccgg tagggaatta
    14161 caccctgccc tgaagatagt tattcaatta cagatgatta tagtacttaa ttttgaatat
    14221 gtcaacagat aaataccgat tgtttttgat atactgtatt tgtgataatc gattctcgct
    14281 cctcggataa agaaaatatg atatactaga taaacgaaat aagagagaag gaatactatg
    14341 tacgcatatt taaaaggaat cattaccaaa attactgcca aatacattgt tcttgaaacc
    14401 aatggtattg gttatatcct gcatgtggcc aatccttatg cctattcagg tcaggttaat
    14461 caggaggctc agatttatgt gcatcaggtt gtgcgtgagg acgcccattt gctttatgga
    14521 tttcgctcag aggatgagaa aaagctcttt cttagtctga tttcggtctc tgggattggt
    14581 cctgtatcag ctcttgctat tatcgctgct gatgacaatg ctggcttggt tcaagccatt
    14641 gaaaccaaga acatcaccta cttgaccaag ttccctaaaa ttggcaagaa aacagcccag
    14701 cagatggtgc tggacttgga aggcaaggta gtagttgcag gagatggcct tcctgccaag
    14761 gtcgcagtgc aagcaagtgc tgaaaaccaa gaattggaag aagctatgga agccatgttg
    14821 gctctgggct acaaggcaac agagctcaag aaaatcaaga aattctttga aggaacgaca
    14881 gatacagctg agaactatat caagtcggcc cttaaaatgt tggtcaaata ggagcagaga
    14941 atgacaaaac gttgttcgtg ggtcaagatg accaacccac tctacatcgc ctatcatgat
    15001 gaggagtggg gccagcccct ccatgatgac caagcgttgt ttgagttatt gtgtatggaa
    15061 acctatcagg caggcctgtc ttgggaaacg gtactcaaca aacgccaagc tttccgagaa
    15121 gcctttcata gctatcaaat tcactcagtc gcagagatga ctgacactga attggaagcc
    15181 atgctggaga atccagctat cattcgaaat agagccaaga tttttgctac acgcgctaac
    15241 gcccaagctt ttctacagtt acaggcagag tacggctctt ttgatgccta tctttggtct
    15301 tttgttgagg ggaaaactgt cgttaacgat gttcctgatt atcgccaagc cccagctaaa
    15361 acacccttat ctgagaaatt agccaaagat ctcaaaaaac gagacttcaa gttcacaggc
    15421 ccagtcgccg tattgtcttt tctacaggct gcagggctag ttgatgacca cgagaatgat
    15481 tgtgagtgga aaggtcttaa atgatgtcta acaaaaataa gggaattctg atttttgcga
    15541 ttctctatac agtcctcttt gtgtttgatg gcgttaaatt gctggcttct ttaatgccat
    15601 ctgccattgc aaattatctt gtttatgtag ttttagctct atatggctcc ttcttattca
    15661 aggatagatt gatccaacaa tggaaggaga ttagaaagac taaaagaaaa ttcttctttg
    15721 gcgtcttaac aggatggctc tttctcattc tgatgactgt tgtctttgaa tttgtatcag
    15781 agatgttgaa gcagtttgtg gggctagtcg gacaaggtct aaatcagtct aatattcaaa
    15841 gcacttttca agagcaacca ctactgatag ctgtttttgc ttgtgtcatt ggacctctgg
    15901 tagaagaatt atttttccgt caggtcttat tgcattactt gcaggaacgg ttgccaggtt
    15961 tactaagcat tattctggta ggacttgttt ttgctctgac tcatatgcac agtttggctc
    16021 tatcagagtg gattggtgca gttggttact taggtggagg ccttgccttt tctattattt
    16081 atgtgaaaga aaaagagaat atctactatc cactacttgt tcacatgtta agcaacagcc
    16141 tctccttaat cattttagct atcagtatag taaaatgaaa taagaacagg acagtcaaat
    16201 cgatttctaa caatgtttta gaagtagatg tgtactattc tagtttcaat ttgctgtaat
    16261 atgtgatgaa aatgccagta atgataccga gaaaaaagct gagaaacttt tcccagcttt
    16321 atttgttata gtcaaagcga atgacttgtt cctgtgcatc tacatgagca tggaccccaa
    16381 agggtacaat tgctcttgga gttgcgtggc cggcattcag attatagaca atcgggatat
    16441 tgctgtcaat gatatccaat agtgcctctt tatagtcgtc atggaaagtt tcatccatag
    16501 gttttccgac caagagtcca ttgatgaccg cgaatatgcc agtgtccttt aaagttagca
    16561 acatcttttt gaagtcttct ggcttaggct tttcttcgct tgtttcgagc aagaggattt
    16621 tcccttccca gtctgacaag tcagggaaaa gtttgtattt ttggcagagc tccgtgctat
    16681 ctgcgtatcg agagttgtca aagatatcgt agagggattc gaggcaacca ccgaggattt
    16741 tcccctcgaa tagtgccctt ccttgcaaca agtcaaaacc tgtatttgta tgactgacac
    16801 gaggtgttcc cagggccgtg ggactaaaat cagttcgttc ctcataccaa acgtcactag
    16861 ggcggatttc tgaaattctt cccgtctcaa tcaattcttt aaagtagtga aggctatagg
    16921 ctagcatttc tttgtctaat tcacaaatgt ctgctaaaaa ggattgacca taaaaagtct
    16981 tgattcctaa tttatgcaac atgaggtggt tcatggttgt atccgagaag ccaagaaaaa
    17041 ttttttgctt gataaccttt tggagttggt cattttcaaa aagataaggt agcaagcgat
    17101 aggtatcgtc tccaccgatg gcacatagga tcatgtcgat gctatcatca gaaaaggcat
    17161 gaatcaaatc ctctgcacga gcttcaggat ggtccttgat aaagtctaat ccttttaacg
    17221 aatggggcaa aaagatggga ttgagtccca gatccttgag acgttggata cccaagtcca
    17281 cttcgtgttt gacaaaatcc tctccgataa tgccactaga taaactaaca ataccaatag
    17341 tagaaaccat atctcatcct cctagaaata gattgagcct attttatcac aaaatataag
    17401 agaaagctat gtgggatttc agaagaatac ttttaatact cttcgaaaat ctcttcaaac
    17461 cacgtcagtt ttatctgcaa cctcaaagct gtgctttgag caacctgcag ctagcttcct
    17521 agtttgctct ttgattttca ttgagtataa ctcaaaaaag taagtgaaaa agcaaccgca
    17581 cctgcagttg cttttatcgt tttcttattc ttgatagcgt gttggtcctg cacttgcact
    17641 acggatattc aagcgtttct tgagatagaa gcgaagggct aggagggctg ctccaataat
    17701 agctagtggc aatggatcca gtactgggtt aaggctagct ggtaggaagc ttgttgcaaa
    17761 gaagacaagc aaccaaagga acacagaagc taggataact agtacagatt tccagaaagg
    17821 tggacgttga ctgcgatcca tatctggtcc atagtattgg taaacaaagt agtacatcaa
    17881 gtagaaggca aatccaccaa ccagtccaac taatagaaga gtaatcaatc catagccgaa
    17941 agcttgatct gccgcaaaga aggttgtgag ggcgctgaca agggcaaaga ggctagtgat
    18001 gaaaagagct gagtccataa tcatcagttt tgggtcatca ttttcttttg gatgctcttt
    18061 ttcgtactgc tctttgacag tgaagctatg agcccaatga gttggtgcgc cgtataggga
    18121 acgggcagtt gtacctttag attgctcctc aaggatttgg ggaatgactt cctcaaaaat
    18181 agtctggatt tcagcgtctg ttttcccatc tttgatgaat tgttgggtag caatgtggac
    18241 aaactcttgg tttttcttag ttaatttttg tagatcaatt tgagacatag gaactccttt
    18301 tagaaccatt ttttatggat gagatagaga gtgagcgaga cactcatagc aaaggcgata
    18361 aagacgatta accagaaggc atttggctct ccgtttaggg gaatttcatt atccttaaag
    18421 ttcatcccgt aggcagaaaa gaccatggtt gggatggaca tgacgatggt cacaagggcc
    18481 aaggttttca tgatgttgtt ctggttgtta gaaatgatag aggcaaaggt ctctgtcata
    18541 gaatgcaaga cgtttccata aatatctgcc atctcgatgg cctgttgggt ttcaatcagg
    18601 gtgtcttcaa gcaggtcttc gtcctcaagg tatttcttga tattgctggt tgaactggtc
    18661 aatttcttaa tcacgcgctc atttgttttg agggaggcct tgaaatagac gatagttttt
    18721 tccaattcca tgagctcaat caattcttca ttacgagttg attgatgcag ttgactttcg
    18781 atttgttcac tcttgcggtc gattgaacga agggctgtta ggtaaagctc tgcattgcga
    18841 taaagaattt gaaagataaa acgtgaacgc atgaaggtat agaaattacg caatcgacgg
    18901 ttgataaaga catcaaggac aggtagtggt tccaaacacg tagtgataat ggtttcctca
    18961 gtgatgataa taccaagcgg gatggttacg tagtaggtgc ggttatttct ttcctccgtg
    19021 accggcacgt ctacgataat cagggtatac tcgtcttcaa tggtaatacg agacatttct
    19081 tccgcatcga gcggtgctcg aaggtcggca atatcaatat cgaaggtgtt ggcgatttcg
    19141 agtgattcat tttgagtcgg attgacgaga ttgatccaag tacccggttc aagcgtatcg
    19201 atctctttaa attcagttgt tgtagagaga aaaacttgtt tcatatccct tatcctttct
    19261 catttttcag attttttcac actgtactat tatactacaa aatcggcctt ttgggtaata
    19321 gaatctcact ttttttggta taatggtaag caataatgga ctagaaagaa caaagatgca
    19381 agataaaatt gtcattcatg gggcgcgtgc ccataattta aaaaatattg atgtggagat
    19441 tccgcgagac aagttggttg tcgtgactgg cttgtcaggt tcagggaagt ccagtttggc
    19501 ttttgatacc ctctatgcgg agggacaacg tcgctatgta gagagtttgt ccgcctacgc
    19561 tcgtcagttc ttgggaaata tggaaaaacc agatgtagat gccattgatg gtctcagccc
    19621 agctatttct atcgaccaga aaacgactag caaaaaccct cgctcgacgg tgggaacaac
    19681 gactgaaatc aatgactatc tgcgtctcct ctacgcgcgt gtggggacgc cttactgtat
    19741 caacgggcat ggggctatca aggcttcttc tgtggagcaa atcgttgata aggttttgga
    19801 gttacctgaa cgccagcgct tgcagatctt gtctcctgtc atccgcaaga aaaaaggcca
    19861 acataagagt gttatcgaga aggttcagaa agacgggtat gttcgtgtcc gtgtggatgg
    19921 ggaagtctat gatgtgaccg aagtgccaga gttgtctaag agcaagcaac acaatatcga
    19981 tgtcgtggtt gaccgtattg ttatcaagga gggcattcgt agtcgtctct ttgattccat
    20041 tgaggctgcc cttcgtattg cagaaggtta tgtcattatc gacaccatgg acaactctga
    20101 gttgttgttc tctgagcatt atgcctgtcc agtttgtggt tttactgtcc cagagttaga
    20161 gcctcgtctc ttttctttca atgctccttt tggctcttgt agtgagtgtg acggcttggg
    20221 catcaagctg gaggtggata ctgatttggt agtgccaaat gccagcaaaa ccttacatga
    20281 gggagcgctg gcaccttgga atcctatctc atccaactac tatccaaaca tgctagagca
    20341 ggccatgacg gcttttggag tggctatgga taagcctttt gaggacttgt cagaagaaga
    20401 caagaacttg attctctacg gctcagatgg taagaaattc catttccact atgagaatga
    20461 atttggtggc gtgcgcgata tcgacattcc gtttgaggga gttatcaata atatcaaacg
    20521 tcgttaccat gaaaccaata gcgattacac tcgcactcag atgcgcctct acatgaatga
    20581 gctgacttgc ggaacctgtc acggttatcg tctcaatgac caggccttgt ctgtccgtgt
    20641 gggtggtgag caagggccac atatcggaga aatttcagac ctgtctatcg cagatcactt
    20701 ggacttggtg agccagttaa ctttgtctga aaatgaagcc atcattgctc gtcccattct
    20761 caaggaaatc aaggatcgtt tgaccttcct taataatgtg ggtcttaact atctaaccct
    20821 gtcacgttca gcaggaaccc tttcaggtgg ggaaagtcag cgcattcgtt tggcaaccca
    20881 gattggttcc aacctatcag gcgtcctcta tatcctagac gagccgtcaa tcggtcttca
    20941 ccagagagac aatgaccgcc tgattgccag tctgaaaaag atgcgtgact tgggcaatac
    21001 tcttatcgtg gtggaacacg acgaagatac catgcgtgaa gctgattatc tgattgacgt
    21061 tggtcctggt gccggtgttt ttggtggtga gattgttgca gcaggtacac ctaagcaagt
    21121 ggctcgcaac agcaagtcta tcacaggtca gtacttgtca ggcaaacgtg tcatcccagt
    21181 accagaagag cgccgtgtcg gaaatggtcg ttttattgaa gtgataggag cgcgtgagaa
    21241 caacttgcaa aatgtcacgg ctcgctttcc actaggaaaa tttatcgcag tgacaggtgt
    21301 gtcgggttca gggaaatcga ctctaatcaa cagcattctc aaaaaagcca ttgcccagaa
    21361 gctcaaccgt aattcagaca aacctggtaa gtttaagact attacaggga ttgagcatgt
    21421 cgaccgtttg attgatattg accagagccc tatcggacgg acgccgaggt ctaacccagc
    21481 tacctataca ggagtttttg acgatatacg tgaccttttt gctcagacaa atgaagccaa
    21541 gattcgaggc tacaagaagg gacgcttcag tttcaacgtc aagggaggtc gctgtgaagc
    21601 ttgctcaggt gacgggatta tcaagattga gatgcacttc ttgccagatg tttatgtggc
    21661 ttgtgaagtt tgccacggaa cccgctataa cagtgaaacc ctagaagttc actacaagga
    21721 aaagaatatt tcgcaggtct tggatatgac ggtcaacgat gcggtagaat ttttccaaca
    21781 cattccgaaa attcaacgca aactccagac catcaaggat gtagggctag gctatgtgac
    21841 cttgggacag ccagctacca ccctttctgg gggagaagcc caacgtatga agttagctag
    21901 cgaactccac aaacgctcga caggaaaatc tttctacatt ctggatgaac cgacgacagg
    21961 gcttcataca gaggacattg ctcgcctgct caaggtttta gctcgctttg tagacgatgg
    22021 caatacagtc ctcgtcatcg agcacaatct ggatgttatc aagacggcag accatatcat
    22081 tgacttggga cctgagggcg gtgtcggtgg tggaaccatc atcgtaacag gaactccaga
    22141 agaagtagct gccaacgaag ccagctatac aggacactat ttgaaaggaa agttacatca
    22201 tgaataaacg cgtacaagca tttctagcta aaatgcaaga aaaagaacta gatggtgtca
    22261 tcatcaacaa tcttaaaaac gtctattatt tgactggttt ttggggctca aacggaacag
    22321 tctttatcag ccgtgaccgt caggtattag tgacagactc tcgctatatc atcgcagcta
    22381 agcaagaaac cagtggtttt gagattgtgg ctgatcgtga tgaattggct gtcattgcag
    22441 gaattgttaa ggacatgggc ttgactcgta tcggttttga agatgagatt tcagtgtctt
    22501 attaccaccg tatgcaggca gcttttgcag gtttgaactt gcttccacaa actcagtttg
    22561 tggaaggtct tcgtatgatt aaggatgagg cagagattgc agcgattcgc aaggcttgtt
    22621 ctatctcaga ccaagctttc cgcgatgcgc ttgactttat caaaccagga aaaactgaaa
    22681 ttgagattgc caacttcctt gatttccgca tgcgtgagtt gggagcatct ggcttatctt
    22741 ttgatacgat cctagctagc ggtatcaatt cttctaaacc ccatgcccat ccaatgcaca
    22801 aaccagtgga gttgggagaa gccattacca tggacttcgg ctgtctctat gaccactatg
    22861 tcagtgatat gacccggact atctatctag ggcatgttag cgatgagcag gcagagattt
    22921 acaatacggt tctaaaagct aaccaagcct tgattgacca agctaaggca ggcttaggtt
    22981 tccgtgactt tgacaaaatc cctcgtgata ttatcattga ggcaggttat ggtgactact
    23041 ttactcacgg cattggccac ggtattggtc tggatatcca tgaggaaccc tactttagtc
    23101 agacttctac agaaactatt aagacaggta tggccttgac cgatgaacca ggtatctata
    23161 tcgaaggcaa atatggcgtt cgtatcgagg atgatatcct gattacagag acaggttgtg
    23221 aattattgac cctagctcca aaagagttga tagtcattta gttgtttgtc aagaaaaaag
    23281 tacgaaaatg acgaaaaaag tcaaaaaaaa tt
//
LOCUS       DAVBEO010000034        22287 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 009
            SAMEA1678075-rid20185393.denovo.034, whole genome shotgun sequence.
ACCESSION   DAVBEO010000034 DAVBEO010000000
VERSION     DAVBEO010000034.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678075
            Sequence Read Archive: ERR226392
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 22287)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22287)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980207.1
            Genome Coverage       :: 150x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:50:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 72 of 147
            Pseudo Genes (incomplete)         :: 72 of 147
            Pseudo Genes (internal stop)      :: 42 of 147
            Pseudo Genes (multiple problems)  :: 32 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22287
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678075-rid20185393.denovo.034"
                     /strain="KS 009"
                     /db_xref="taxon:1313"
     gene            complement(160..2118)
                     /gene="ftsH"
                     /locus_tag="VQ543_001361"
     CDS             complement(160..2118)
                     /gene="ftsH"
                     /locus_tag="VQ543_001361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000744538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HET2612080.1"
                     /translation="MKKQNNGLIKNPFLWLLFIFFLVTGFQYFYSGNNSGGSQQINYT
                     ELVQEITDGNVKELTYQPNGSVIEVSGVYKNPKTSKEETGIQFFTPSVTKVEKFTSTI
                     LPADTTVSELQKLATDHKAEVTVKHESSSGIWINLLVSIVPFGILFFFLFSMMGNMGG
                     GNGRNPMSFGRSKAKAANKEDIKVRFSDVAGAEEEKQELVEVVEFLKDPKRFTKLGAR
                     IPAGVLLEGPPGTGKTLLAKAVAGEAGVPFFSISGSDFVEMFVGVGASRVRSLFEDAK
                     KAAPAIIFIDEIDAVGRQRGVGLGGGNDEREQTLNQLLIEMDGFEGNEGIIVIAATNR
                     SDVLDPALLRPGRFDRKVLVGRPDVKGREAILKVHAKNKPLAEDVDLKLVAQQTPGFV
                     GADLENVLNEAALVAARRNKSIIDASDIDEAEDRVIAGPSKKDKTVSQKERELVAYHE
                     AGHTIVGLVLSNARVVHKVTIVPRGRAGGYMIALPKEDQMLLSKEDMKEQLAGLMGGR
                     VAEEIIFNVQTTGASNDFEQATQMARAMVTEYGMSEKLGPVQYEGNHAMFGAQSPQKS
                     ISEQTAYEIDEEVRSLLNEARNKAAEIIQSNREIHKLIAEALLKYETLDSTQIKALYE
                     TGKMPEAVEEESHALSYDEVKSKMNDEK"
     gene            complement(2134..2676)
                     /gene="hpt"
                     /locus_tag="VQ543_001362"
     CDS             complement(2134..2676)
                     /gene="hpt"
                     /locus_tag="VQ543_001362"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HET2612081.1"
                     /translation="MLENDIKKVLVSHDEITEAAKKLGAQLTKDYAGKNPILVGILKG
                     SIPFMAELVKHIDTHIEMDFMMVSSYHGGTASSGVINIKQDVTQDIKGRHVLFVEDII
                     DTGQTLKNLRDMFKAREAASVKIATLLDKPEGRVVEIEADYTCFTIPNEFVVGYGLDY
                     KENYRNLPYIGVLKEEVYSN"
     gene            complement(2680..3957)
                     /gene="tilS"
                     /locus_tag="VQ543_001363"
     CDS             complement(2680..3957)
                     /gene="tilS"
                     /locus_tag="VQ543_001363"
                     /EC_number="6.3.4.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA lysidine(34) synthetase TilS"
                     /protein_id="HET2612082.1"
                     /translation="MREPDFLNHFLKKGYFKKHAKAVLALSGGLDSMFLFKVLSTYQK
                     ELEIELILAHVNHKQRIESDWEEKELRKLAAEAELPIYISNFSGEFSEARARNFRYDF
                     FQEVMKKTGATALVTAHHADDQVETILMRLIRGTRLRYLSGIKEKQVVGEIEIIRPFL
                     HFQKKDFPSIFHFEDTSNQENHYFRNRIRNSYLPELEKENPRFRDAILGIGNEILDYD
                     LAIAELSNNINVEDLQQLFSYSESTQRVLLQTYLNRFPDLNLTKAQFAEVQQILKSKS
                     QYRHPIKNGYELIKEYQQFQICKISPQADEEEDELVLHYQNQVAYQGYLFSFGLPLEG
                     ESIQQIPVSRETSIHIRHRKTGDVLIQNGHRKKLRRLFIDLKIPMEKRNSALIIEQFG
                     EIVSILGIATNNLSKKTKNDIMNTVLYIEKIDR"
     gene            complement(3954..5222)
                     /locus_tag="VQ543_001364"
     CDS             complement(3954..5222)
                     /locus_tag="VQ543_001364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class A beta-lactamase-related serine hydrolase"
                     /protein_id="HET2612083.1"
                     /translation="MRKFLIILLLPSFLTISKVVSTEKEVVYTSKEIYYLSQSDFGIY
                     FREKLSSPMVYGEVPVYANEDLVVESGKLTPKTSFQITEWRLNKQGIPVFKLSNHQFI
                     AADKRFLYDQSEVTPTIKKAWLESDFKLYNSPYDLKEVKSSLSAYSQVSIDKTMFVEG
                     REFLHIDQAGWVAKESTSEEDNRMSKVQEMLSEKYQKDSFSIYVKQLTTGKEAGINQD
                     EKMYAASVLKLSYLYYTQEKINEGLYQLDTTVKYVSAVNDFPGSYKPEGSGSLPKKED
                     NKEYSLKDLITKVSKESDNVAHNLLGYYISNQSDATFKSKMSAIMGDDWDPKEKLISS
                     KMAGKFMEAIYNQNGFVLESLTKTDFDSQRIAKGVSVKVAHKIGDADEFKHDTGVVYA
                     DSPFILSIFTKNSDYDTISKIAKDVYEVLK"
     gene            complement(5342..5710)
                     /locus_tag="VQ543_001365"
     CDS             complement(5342..5710)
                     /locus_tag="VQ543_001365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation initiator family protein"
                     /protein_id="HET2612084.1"
                     /translation="MSKNIVQLNNSFIQNEYQRRRYLMKERQKRNRFMGGVLILIMLL
                     FILPTFNLAQSYQQLLQRRQQLADLQTQYQTLSDEKDKETAFATKLKDEDYAAKYTRA
                     KYYYSKSREKVYTIPDLLQR"
     gene            complement(5703..5969)
                     /locus_tag="VQ543_001366"
     CDS             complement(5703..5969)
                     /locus_tag="VQ543_001366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001234972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding S4 domain-containing protein"
                     /protein_id="HET2612085.1"
                     /translation="MRLDKYLKVSRIIKRRTVAKEVADKGRIKVNGILAKSSTDLKVN
                     DQVEIRFGNKLLLVKVLEMKDSTKKEDAAGMYEIISETRVEENV"
     gene            complement(6027..9536)
                     /gene="mfd"
                     /locus_tag="VQ543_001367"
     CDS             complement(6027..9536)
                     /gene="mfd"
                     /locus_tag="VQ543_001367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000258090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription-repair coupling factor"
                     /protein_id="HET2612086.1"
                     /translation="MVTLLDLFSENDQIKKWHQNLTDKKRQLILGLSTSTKALAIASS
                     LEKEDRIVLLTSTYGEAEGLVSDLISILGEELVYPFLVDDAPMVEFLMSSQEKIISRV
                     EALRFLTDSSKKGILVCNIAASRLILPSPNAFKDSIVKISVGEEYAQHAFIHQLKENG
                     YQKVTQVQTQGEFSLRGDILDIFEISQLEPCRIEFFGDEIDGIRSFEVETQLSKENKT
                     ELTIFPASDMLLREKDYQRGQSALEKQISKTLSPILKSYLEEILSSFHQKQSHADSRK
                     FLSLCYDKTWTVFDYIEKDTPIFFDDYQKLMNQYEVFERELAQYFTEELQNSKAFSDM
                     QYFSDIEQIYKKQSPVTFFSNLQKGLGNLKFDKIYQFNQYPIQEFFNQFSFLKEEIER
                     YKKMDYTIILQSSNSMGSKTLEDMLEEYQIKLDSRDKTSICKESVNLIEGNLRHGFHF
                     VDEKILLITEHEIFQKKLKRRFRRQHVSNAERLKDYNELEKGDYVVHHIHGIGQYLGI
                     ETIEIKGIHRDYVSVQYQNGDQISIPVEQIHLLSKYISSDGKAPKLNKLNDGHFKKAK
                     QKVKNQVEDIADDLIKLYSERSQLKGFAFSADDDDQDAFDDAFPYVETDDQLRSIEEI
                     KRDMQASQPMDRLLVGDVGFGKTEVAMRAAFKAVNDHKQVVILVPTTVLAQQHYTNFK
                     ERFQNFAVNIDVLSRFRSKKEQTATLEKLKNGQVDILIGTHRVLSKDVVFADLGLMII
                     DEEQRFGVKHKETLKELKKQVDVLTLTATPIPRTLHMSMLGIRDLSVIETPPTNRYPV
                     QTYVLEKNDSVIRDAVLREMERGGQVYYLYNKVDTIVQKVSELQELIPEASIGYVHGR
                     MSEVQLENTLLDFIEGQYDILVTTTIIETGVDIPNANTLFIENADHMGLSTLYQLRGR
                     VGRSNRIAYAYLMYRPEKSISEVSEKRLEAIKGFTELGSGFKIAMRDLSIRGAGNLLG
                     KSQSGFIDSVGFELYSQLLEEAIAKRNGNANANTRTKGNAELILQIDAYLPDTYISDQ
                     RHKIEIYKKIRQIDNRVNYEELQEELIDRFGEYPDVVAYLLEIGLVKSYLDKVFVQRV
                     ERKDNKITIQFEKVTQRLFLAQDYFKALSVTNLKAGIAENKGLMELVFDVQNKKDYEI
                     LEGLLIFGESLLEIKEFKEENSI"
     gene            complement(9537..10106)
                     /locus_tag="VQ543_001368"
     CDS             complement(9537..10106)
                     /locus_tag="VQ543_001368"
                     /EC_number="3.1.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA hydrolase"
                     /protein_id="HET2612087.1"
                     /translation="MTKLLVGLGNPGDKYFETKHNVGFMLIDQLAKKQNVTFTHDKIF
                     QADLASFFLNGEKIYLVKPTTFMNESGKAVHALLTYYGLDIDDLLIIYDDLDMEVGKI
                     RLRAKGSAGGHNGIKSIIQHIGTQVFNRVKIGIGRPKNGMSVVHHVLSKFDRDDYIGI
                     LQSVDKVDDSVKYYLQEKNFEKTMQRYNG"
     gene            complement(10177..11292)
                     /gene="ychF"
                     /locus_tag="VQ543_001369"
     CDS             complement(10177..11292)
                     /gene="ychF"
                     /locus_tag="VQ543_001369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002269933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-regulated ATPase YchF"
                     /protein_id="HET2612088.1"
                     /translation="MALTAGIVGLPNVGKSTLFNAITKAGAEAANYPFATIDPNVGMV
                     EVPDERLQKLTEMITPKKTVPTTFEFTDIAGIVKGASKGEGLGNKFLANIREVDAIVH
                     VVRAFDDENVMREQGREDAFVDPLADIDTINLELILADLESVNKRYARVEKMARTQKD
                     KESVAEFNVLQKIKPVLEDGKSARTIEFTDEEQKVVKGLFLLTTKPVLYVANVDEDVV
                     SEPDSIDYVKQIREFAATENAEVVVISARAEEEISELDDEDKKEFLEAIGLTESGVDK
                     LTRAAYHLLGLGTYFTAGEKEVRAWTFKRGMKAPQAAGIIHSDFEKGFIRAVTMSYED
                     LVKYGSEKAVKEAGRLREEGKEYIVQDGDIIEFRFNV"
     gene            complement(11376..11570)
                     /locus_tag="VQ543_001370"
     CDS             complement(11376..11570)
                     /locus_tag="VQ543_001370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF951 family protein"
                     /protein_id="HET2612089.1"
                     /translation="MYQVGNFVEMKKSHACTIKSTGKKANRWEITRVGADIKIKCSNC
                     EHVVMMGRYDFERKMNKIID"
     gene            complement(11635..12771)
                     /gene="dnaN"
                     /locus_tag="VQ543_001371"
     CDS             complement(11635..12771)
                     /gene="dnaN"
                     /locus_tag="VQ543_001371"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000581170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit beta"
                     /protein_id="HET2612090.1"
                     /translation="MIHFSINKNLFLQALNTTKRAISSKNAIPILSTVKIDVTNEGIT
                     LIGSNGQISIENFISQKNEDAGLLITSLGSILLEASFFINVVSSLPDVTLDFKEIEQN
                     QIVLTSGKSEITLKGKDSEQYPRIQEISASTPLILETKLLKKIINETAFAASTQESRP
                     ILTGVHFVLSQHKELKTVATDSHRLSQKKLTLEKNSDDFDVVIPSRSLREFSAVFTDD
                     IETVEIFFANNQILFRSENISFYTRLLEGNYPDTDRLIPTDFNTTITFNVVNLRQSME
                     RARLLSSATQNGTVKLEIKDGVVSAHVHSPEVGKVNEEIDTDQVTGEDLTISFNPTYL
                     IDSLKALNSEKVTISFISAVRPFTLVPADTDEDFMQLITPVRTN"
     gene            complement(12921..14282)
                     /gene="dnaA"
                     /locus_tag="VQ543_001372"
     CDS             complement(12921..14282)
                     /gene="dnaA"
                     /locus_tag="VQ543_001372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosomal replication initiator protein DnaA"
                     /protein_id="HET2612091.1"
                     /translation="MKEKQFWNRILEFAQERLTRSMYDFYAIQAELIKVEENVATIFL
                     PRSEMEMVWEKQLKDIIVVAGFEIYDAEITPHYIFTKPQDTTSSQVEEATNLTLYNYS
                     PKLVSIPYSDTGLKEKYTFDNFIQGDGNVWAVSAALAVSEDLALTYNPLFIYGGPGLG
                     KTHLLNAIGNEILKNIPNARVKYIPAESFINDFLDHLRLGEMEKFKKTYRSLDLLLID
                     DIQSLSGKKVATQEEFFNTFNALHDKQKQIVLTSDRSPKHLEGLEERLVTRFSWGLTQ
                     TITPPDFETRIAILQSKTEHLGYNFQSDTLEYLAGQFDSNVRDLEGAINDITLIARVK
                     KIKDITIDIAAEAIRARKQDVSQMLVIPIDKIQTEVGNFYGVSIKEMKGSRRLQNIVL
                     ARQVAMYLSRELTDNSLPKIGKEFGGKDHTTVIHAHAKIKSLIDQDDNLRLEIESIKK
                     KIK"
     gene            complement(14495..15253)
                     /locus_tag="VQ543_001373"
     CDS             complement(14495..15253)
                     /locus_tag="VQ543_001373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000410347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family partition protein"
                     /protein_id="HET2612092.1"
                     /translation="MEKFEMISITDIQKNPYQPRKEFDREKLDELAQSIKENGVIQPI
                     IVRQSPVIGYEILAGERRYRASLLAGLRSIPAVVKQISDQEMMVQSIIENLQRENLNP
                     IEEARAYESLVEKGFTHAEIADKMGKSRPYISNSIRLLSLPEQILSEVENGKLSQAHA
                     RSLVGLNKEQQDYFFQRIIEEDISVRKLEALLTEKKQKKQQKTNHFIQNEEKQLRKLL
                     GLDVEIKLSKKDSGKIIISFSNQEEYSRIINSLK"
     gene            complement(15311..16492)
                     /locus_tag="VQ543_001374"
     CDS             complement(15311..16492)
                     /locus_tag="VQ543_001374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000681590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine protease"
                     /protein_id="HET2612093.1"
                     /translation="MKHLKTFYKKWFQLLVVIVISFFSGALGSFSITQLTQKSSVNNS
                     NNNSTITQTAYKNENSTTQAVNKVKDAVVSVITYSANRQNSVFGNDDTDTDSQRISSE
                     GSGVIYKKNDKEAYIVTNNHVINGASKVDIRLSDGTKVPGEIVGADTFSDIAVVKISS
                     EKVTTVAEFGDSSKLTVGETAIAIGSPLGSEYANTVTQGIVSSLNRNVSLKSEDGQAI
                     STKAIQTDTAINPGNSGGPLINIQGQVIGITSSKIATNGGTSVEGLGFAIPANDAINI
                     IEQLEKNGKVTRPALGIQMVNLSNVSTSDIRRLNIPSNVTSGVVVRSVQSNMPANGHL
                     EKYDVITKVDDKEIASSTDLQSALYNHSIGDTIKITYYRNGKEETTSIKLNKSSGDLE
                     S"
     gene            16675..17154
                     /gene="rlmH"
                     /locus_tag="VQ543_001375"
     CDS             16675..17154
                     /gene="rlmH"
                     /locus_tag="VQ543_001375"
                     /EC_number="2.1.1.177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000695929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (pseudouridine(1915)-N(3))-methyltransferase RlmH"
                     /protein_id="HET2612094.1"
                     /translation="MKIKVVTVGKLKEKYLKDGIAEYSKRISRFAKFEMIELSDEKTP
                     DKASESENQKILEIEGQRILSKIADRDFVIVLAIEGKTFFSEEFSKQLEETSIKGFST
                     LTFIIGGSLGLSSSVKNRANLSVSFGRLTLPHQLMRLVLVEQIYRAFTIQQGFPYHK"
     gene            17198..17271
                     /locus_tag="VQ543_001376"
     tRNA            17198..17271
                     /locus_tag="VQ543_001376"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:17232..17234,aa:Arg,seq:tct)
     gene            17436..17561
                     /gene="comC"
                     /locus_tag="VQ543_001377"
     CDS             17436..17561
                     /gene="comC"
                     /locus_tag="VQ543_001377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000799689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence-stimulating peptide ComC"
                     /protein_id="HET2612095.1"
                     /translation="MKNTVKLEQFVALKEKDLQKIKGGEMRLSKFFRDFILQRKK"
     gene            17582..18907
                     /locus_tag="VQ543_001378"
     CDS             17582..18907
                     /locus_tag="VQ543_001378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000362880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HET2612096.1"
                     /translation="MDLFGFGTVIVHFLIISHSYHFICKGQINRKELFVFGAYTLLTE
                     IVFDFPLYILYLDGLGIERFLFPLGLYSYFRWMKQYERDRGLFLSLLLSLLYESTHNF
                     LSVTFSSITGDNFVLQYHFPFFFVVTVLTYFVTLKIIYYFHLELAYFDEDYLYPFLKK
                     VFFALLLLHIVSFVSDMVSTIKHLNSFGSILSSIVFISLLLTFFAMNSHKVQMEKEIA
                     LKQKKFEQKHLQNYTDEIVGLYNEIRGFRHDYAGMLVSMQMAIDSGNLQEIDRIYNEV
                     LVKANHKLRSDKYTYFDLNNIEDSALRSLVAQSIVYARNNGVEFTLEVKDTITKLPIE
                     LLDLVRIMSVLLNNAVEGSADSYKKQMEVAVIKMETETVIVIQNSCKMTMTPSGDLFA
                     LGFSTKGRNRGVGLNNVKELLDKYNNIILETEMEGSTFRQIIRFKREFE"
     gene            18904..19656
                     /locus_tag="VQ543_001379"
     CDS             18904..19656
                     /locus_tag="VQ543_001379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000866085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET2612097.1"
                     /translation="MKVLILEDVIEHQVRLERILDEISKESNIPISYKTTGKVREFEE
                     YIENDEVNQLYFLDIDIHGIEKKGFEVAQLIRHYNPYAIIVFITSRSEFATLTYKYQV
                     SALDFVDKDINDEMFKKRIEQNIFYTKSMLLENEDVVDYFDYNYKGNDLKIPYHDILY
                     IETTGVSHKLRIIGKNFAKEFYGTMTDIQEKDKHTQRFYSPHKSFLVNIGNIREIDRK
                     NLEIVFYEDHRCPISRLKIRKLKDILEKKSQK"
     gene            19708..19779
                     /locus_tag="VQ543_001380"
     tRNA            19708..19779
                     /locus_tag="VQ543_001380"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:19741..19743,aa:Glu,seq:ttc)
     gene            19785..19858
                     /locus_tag="VQ543_001381"
     tRNA            19785..19858
                     /locus_tag="VQ543_001381"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:19819..19821,aa:Asn,seq:gtt)
     gene            complement(19899..20441)
                     /locus_tag="VQ543_001382"
     CDS             complement(19899..20441)
                     /locus_tag="VQ543_001382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator
                     C-terminal domain-containing protein"
                     /protein_id="HET2612098.1"
                     /translation="MQESNKRLKTKRTIENAMVQLLMEQPFDKISTVKLVEKAGISRS
                     SFYTHYKDKYDMIEHYQSKLFHTFEYIFQKHAHHKRDAILEVFEYLESEPLLAALLSE
                     NGTKEIQNFLRNKLHIMLSTDLQKRFMQLNLNTTELEYSSIYLTHALFGVCQTWIAHG
                     KKESSQEITDFLMKMLGDTN"
     gene            20620..21387
                     /locus_tag="VQ543_001383"
     CDS             20620..21387
                     /locus_tag="VQ543_001383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip domain-containing protein"
                     /protein_id="HET2612099.1"
                     /translation="MIGISLIPDLYNIIFLSSMWDPYGQLSDLPVAVVNNDKEASYNG
                     NTMAIGKDMVSNLKENKTLDFHFVDEEEGKKGLEDGDYYMVVTLPSDLSEKTTTLSNI
                     QSTAAYQSLTSEQQTEISDSVSQNSTDSIQSAQSIVALVQDLQGSLENLQNQSSNLST
                     LKNQSNQVSPITSTSLIGLSSGLTEIQGDVTSKLVPASQSIASGVNAYTTGVDKVSQG
                     ASQLSEKNATLTGSLDKLVSGSNTLTQKSSRLTAGVG"
     gene            21472..22152
                     /locus_tag="VQ543_001384"
     CDS             21472..22152
                     /locus_tag="VQ543_001384"
                     /inference="COORDINATES: protein motif:HMM:TIGR03057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip family protein"
                     /protein_id="HET2612100.1"
                     /translation="MADGSGKLAEGGTKLTSGLEDLQTGLASLGQGLGNASDQLKSVS
                     TESKNAEILSNPLNLSKTDNDQVPVNGIAIAPYMISVALFVAAISTNMIFAKLPSGRH
                     PESRWAWLKSRAEINGIIAVLAGILVYGGVQLIGLTANHEMRIFILIILTSLVFMSMV
                     TTLTTWNSRIGAFFLLILLLLQLASSAGTYPLALTNDFFRSINPWLPMSYSVSGLRQT
                     ISINKSFS"
BASE COUNT         6886 a         4110 c         3640 g         7651 t
ORIGIN      
        1 acagtccctt ggacttcttc atacaattct ttaatcataa ttttcccctt tctagataca
       61 gtctaacaga ttagaaaaca catttgttcc attttctcca ttctgttccc tttagctcct
      121 aaactgcaca aaaaagagag gctccagcct ctctcagggt tatttttcgt cattcatttt
      181 tgactttact tcatcatagg atagtgcatg agattcctct tctactgctt caggcatctt
      241 tcctgtttcg taaagagctt taatttgtgt actatccaat gtttcgtatt tcaataatgc
      301 ttctgcaatt aacttgtgaa tttcacgatt tgactgaata atttcagcag ctttatttcg
      361 tgcctcattt aataatgaac gaacctcttc atcaatttca taagctgttt gttctgaaat
      421 tgatttttga ggactctgtg caccaaacat agcatggttt ccttcatatt gtactgggcc
      481 aagtttttca ctcataccgt actctgtaac cattgcacgc gccatttgtg tcgcttgttc
      541 aaagtcgttt gaagctcctg tagtttggac attaaagata atttcttcag ctacacgtcc
      601 acccattaag ccagccaatt gctctttcat atcttcttta gatagaagca tttgatcctc
      661 tttaggaagt gcaatcatgt atccgcctgc acggccgcgt ggtacaattg taaccttatg
      721 gacaacgcga gcattcgaca agactagacc aacaatggta tgtcctgcct catggtaagc
      781 aaccaattct cgttcttttt gtgaaactgt cttatctttc ttagaaggtc cagcaataac
      841 tctatcttct gcttcatcaa tatctgaagc atcaattatc gatttattgc gacgagcagc
      901 aactaaagct gcttcattca agacattctc taaatcagca ccaacaaagc ctggagtttg
      961 ttgagccact aatttcaaat caacatcttc tgctaaaggc ttgttcttag cgtgaacttt
     1021 caagattgct tcacgacctt taacatcagg acgaccaacc aatacttttc tatcaaaacg
     1081 tcctggacgc aaaagggcag gatcaagtac atctgaacgg tttgtcgcag cgatgacgat
     1141 aatcccttca tttccctcaa aaccatccat ctcaatcaaa agttggttca aggtttgttc
     1201 acgttcgtca ttacctccgc cgagaccgac tccacgttga cgtccaacag catcaatttc
     1261 atcgataaag atgatagctg gtgctgcttt tttggcatcc tcaaaaagag agcgaacacg
     1321 actagctcca actccgacaa acatttctac aaagtcagaa cctgagatac taaagaatgg
     1381 aacacctgct tctccagcga ctgccttagc aagcaaagtt ttacctgtcc ccggaggtcc
     1441 ctccaaaaga acacctgctg gaatacgggc tccaagtttt gtgaatcgtt ttggatcttt
     1501 taagaactca acaacttcaa ctagttcttg tttttcttcc tcagctccag caacatctga
     1561 aaatcttact ttaatatctt ctttatttgc tgctttagcc ttactacgtc caaaactcat
     1621 tggattacgg ccattgcctc ctcccatatt tcccatcata gagaatagga agaagaatag
     1681 aattccaaat ggcacaatgg atacgagtag attaatccat ataccacttg aactttcatg
     1741 cttaacagtt acttctgctt tatggtcagt agcaagtttt tgcaattctg atacggtagt
     1801 atctgcagga agaatagtgc tggtaaattt ctctacctta gtaacagatg gcgtgaaaaa
     1861 ctgaatacct gtttcttctt tacttgtttt aggattttta tagacaccag aaacttcgat
     1921 aacactacca tttggttggt aagttaattc ttttacatta ccatcggtaa tttcttgtac
     1981 caactcagta tagttgattt gctgacttcc tcctgagtta ttcccagaat agaaatactg
     2041 gaatcctgtc acaaggaaaa agataaataa taaccataga aaaggatttt taattaaacc
     2101 attattttgt tttttcatta aagattattc tttctaattt gaatacactt cctctttcaa
     2161 tactccaata taaggaagat tacgataatt ttctttgtag tctaaaccat aacctactac
     2221 aaactcattt gggatagtaa agcaggtata gtctgcctca atttctacaa cacgtccttc
     2281 tggtttatcc aacaaggttg caattttaac agaagctgct tctcttgctt taaacatatc
     2341 tcgcaaattc ttcaaagttt gacctgtatc aatgatatct tctacaaata gaacatgtct
     2401 tcctttgata tcttgagtca catcttgttt aatattgata acaccactac ttgctgttcc
     2461 accatggtag ctagaaacca tcatgaagtc catttcaata tgtgtatcaa tatgtttgac
     2521 caattcagcc ataaaaggaa tagatccttt taaaatccca actaagattg gattttttcc
     2581 tgcatagtct ttagttaatt gagcacctag ttttttagct gcttctgtaa tttcatcgtg
     2641 tgaaacgagg acttttttaa tatcgttttc taacattttt tacctatcta ttttttctat
     2701 ataaagtaca gtgttcatta tatcattttt cgttttttta ctcaaattat tggtcgcaat
     2761 tcccaaaatt gagacaattt caccaaattg ctcaataata agagcagagt ttctcttttc
     2821 catagggatt ttcaaatcaa taaataaacg tctgagtttt tttctatgcc cattttgaat
     2881 caaaacatct cctgtttttc gatgacgaat gtgtatggat gtttcacgtg aaacaggtat
     2941 ttgttgaatt gattcacctt ctaatggaag tccaaaggaa aataaatatc cttgataagc
     3001 tacctgattt tgatagtgta acacaagttc atcttcctct tcatcagcct gcggactgat
     3061 tttacaaatc tgaaactgtt ggtactcttt tatcaattca tagccatttt taatcggatg
     3121 acgatactgg cttttagatt ttaaaatctg ctgaacttca gcaaactgag cttttgtaag
     3181 attcaaatct ggaaaacgat tcagataagt ttgaagtaaa actctttgtg tagactcaga
     3241 gtaagaaaat aactgctgta aatcttccac attaatattg ttagataatt cagctattgc
     3301 caaatcataa tctaaaattt cattgccaat gcctaagatt gcatccctaa atcgaggatt
     3361 ttctttttcc aattctggta agtaagagtt tcgaatacga tttcgaaaat aatgattctc
     3421 ctgatttgat gtatcttcaa agtgaaaaat tgatggaaag tcttttttct gaaaatgcaa
     3481 gaagggacga atgatttcta tctctccgac tacttgcttc tccttaattc ctgatagata
     3541 gcgcaagcga gttcctcgaa tcaagcgcat caaaatcgtt tccacctgat catcagcatg
     3601 gtgggcagtg actaaagctg tcgcacctgt ctttttcatg acctcttgaa aaaaatcata
     3661 acgaaaattt cgtgcacgcg cttctgaaaa ttctcctgaa aaattgctga tataaatagg
     3721 aagctctgct tcagcagcca acttccttaa ttccttttct tcccaatctg attcaattct
     3781 ctgcttatga ttcacatgag ctagaatcaa ttcaatctct aactcttttt gataagtaga
     3841 caatacctta aatagaaaca tggaatctaa tccaccagaa agagctagaa ccgccttagc
     3901 atgctttttg aaatatccct tcttgagaaa atgatttaaa aaatctggtt ccctcatttt
     3961 agaacctcat aaacatcctt ggctatctta gaaatcgtat cataatcaga attcttagtg
     4021 aaaatagaaa gaataaatgg agaatctgca tagacaacac ccgtatcatg cttaaattca
     4081 tccgcatctc caattttatg agctacttta acagaaacac ctttggcaat tcgctgacta
     4141 tcaaaatctg ttttagtcaa agactctaac acaaatccat tttgattata aatagcttcc
     4201 ataaacttcc cggccatctt agaagaaatc aatttttctt ttggatccca atcatctccc
     4261 ataatggcag acatcttgga tttgaatgtg gcatcagatt ggtttgaaat gtaatatccc
     4321 aatagattat gagctacatt atcagattct tttgatactt tcgtaattaa atcctttaaa
     4381 gaatattctt tattatcttc ttttttagga agactaccac ttccctctgg tttataagaa
     4441 cctggaaaat cattgactgc agatacgtat tttacagtcg tatctaactg ataaagaccc
     4501 tcatttattt tttcttgcgt ataatagaga taagagagtt tcaaaacgct ggctgcatac
     4561 atcttttcat cttgattgat accagcttct tttccagtag tcagttgctt aacataaata
     4621 gagaaagaat ctttctgata tttttcagat aacatttctt gaactttact catccgatta
     4681 tcttcttcag aagttgattc tttagctacc catccagcct gatcaatatg tagaaattct
     4741 cttccttcta caaacatggt cttgtcgatt gatacttgcg aataagctga taaggatgat
     4801 ttcacttctt ttaaatcata aggactattg tacagtttaa agtcagattc taaccatgct
     4861 ttttttattg ttggagttac ctctgattga tcatataaaa atcgtttgtc cgcagctata
     4921 aattgatgat ttgatagctt aaatactgga attccttgtt tatttaagcg ccactcggtt
     4981 atttgaaaac ttgttttggg agtcaatttc ccagattcca ctactaaatc ttcattcgca
     5041 taaacaggaa cctctccata aaccatggga gaacttaatt tttctctaaa ataaatacca
     5101 aagtcagatt gtgaaaggta ataaatttct ttcgaagtat agacgacttc tttttctgtg
     5161 ctaacgactt ttgaaatggt caaaaaactt ggtagcaaca aaataattaa gaatttacgc
     5221 attcttcctt tccttttctt cttgtaaacg caataattga tttttatcag ccaattcttc
     5281 cagcttttca tctgacaaac tcaaaaattg ctctattacg tctaataaat tttccatttt
     5341 atcacctttg aagcaagtca ggaatcgtat aaactttttc cctcgactta gaataatagt
     5401 acttcgctcg tgtatatttg gcagcataat cttcatcttt caacttggta gcaaatgctg
     5461 tctccttatc cttttcatca ctcaaagttt gatactgagt ttgcaagtct gctaattgct
     5521 gacgtctttg gagtaattgc tgataactct gcgctaaatt aaaagttggc aagataaata
     5581 atagcataat caaaatcaat acccctccca taaaacgatt ccgtttttgt cgttctttca
     5641 tcaggtagcg acgacgttgg tattcatttt gaataaaaga attattcaat tgtacaatat
     5701 ttttagacat tttcttctac ccgtgtttca ctgataattt catacattcc tgctgcatct
     5761 tctttttttg tactatcttt catctctagt acttttacaa gcagcaactt attgccaaag
     5821 cgaatttcaa cttggtcatt aactttcaag tccgttgaac ttttggccaa gattccatta
     5881 accttgattc tacctttatc tgctacttcc tttgcgactg tacgacgctt gataattcgc
     5941 gatactttta aatatttatc taatctcatc cttattacct caatttatta ttgtaccatt
     6001 tttatctatt ttatagaaga aaaatatcaa atggaatttt cttccttaaa ctcttttatc
     6061 tctaataaac tttctccaaa aatcagcaga ccttctaaaa tttcataatc tttcttattt
     6121 tggacatcaa atacaagctc cattaatccc ttattctcag cgatgcctgc ttttaagttc
     6181 gttacggata aagctttaaa ataatcttga gctaaaaaca atcgttgagt gactttttca
     6241 aattgaattg taattttatt atcttttctt tccacacgtt gaacaaagac cttgtccaag
     6301 tatgatttaa ccaaaccaat ctctaaaaga taggctacta catctgggta ttctccaaaa
     6361 cggtctatca actcctcttg taactcttca taattgacac ggttgtcaat ttgacgaatt
     6421 ttcttgtaaa tttcaatctt atgtcgttga tcagaaatat aagtatcagg aagataggca
     6481 tcaatttgca aaatcaactc agcattccct ttggttcttg tgttagcgtt agcattaccg
     6541 tttcgtttag caatagcttc ctctaataac tgcgaataca attcaaaacc aacagaatca
     6601 atgaaaccag actgggattt tcctaaaaga tttcctgctc cacgaatcga aagatctcgc
     6661 attgcaatct taaagccaga gcccaattct gtaaatcctt taatcgcttc taatctcttt
     6721 tcagagactt cactgattga tttttctgga cgatacatga gataagcata agcaatacga
     6781 ttactacgac cgactcttcc tcttaactga tataaggttg acaagcccat atggtccgca
     6841 ttttcaataa ataaagtatt agcatttgga atgtccaccc ctgtctcaat aatagtagtc
     6901 gtcaccaaga tatcgtattg tccctcaata aagtctaata gagtattttc caactggact
     6961 tcactcattc gaccatgaac atatccaatc gaagcctccg gaatcaactc ctgtaattct
     7021 gaaaccttct gaacaattgt gtcaactttg ttgtaaagat aataaacttg acctccacgc
     7081 tccatttcac gcaagacagc atcacgaatg acactatcat tcttttccaa aacataggtc
     7141 tgaacaggat agcgattagt cggcggagtt tcaataacag ataaatctct gattcccagc
     7201 atagacatat ggagggtacg agggattggc gtagcggtca aggttaggac atccacttgt
     7261 ttcttcagtt ctttcaaagt ttccttatgc ttgacaccaa atcgctgttc ctcatcaata
     7321 atcatcaagc ccaaatcagc aaacacaaca tcttttgaca aaacacgatg tgttccaatc
     7381 aaaatatcga cttgaccgtt tttcaatttt tcaagtgttg cagtctgctc ttttttactt
     7441 ctaaagcgac tcaacacatc aatattaact gcaaaatttt ggaatcgttc cttaaaattc
     7501 gtatagtgct gttgcgctaa aaccgtcgtc ggaactagaa tgacaacctg tttgtgatca
     7561 ttgactgctt taaaggctgc acgcatagca acttcagtct ttccaaaacc aacatcccca
     7621 actaaaagtc gatccattgg ctgagaagcc tgcatatccc tcttgatttc ctcaatacta
     7681 cgaagttgat catccgtttc aacataaggg aaagcatcat caaaggcatc ttgatcatca
     7741 tcatcagctg agaaagcaaa acccttcaac tgactacgtt cagagtagag tttgattaaa
     7801 tcatcagcta tatcctctac ctggttctta accttttgct tggccttttt aaaatgaccg
     7861 tcatttaatt tattgagttt tggagcttta ccatcacttg aaatatattt ggacagtaga
     7921 tgaatctgtt ccacggggat agaaatttga tcaccatttt ggtattggac actgacataa
     7981 tcgcgatgaa ttcccttgat ttcaatggtt tcaattccta gatattgacc aatcccatgg
     8041 atatgatgga caacatagtc ccctttttca agttcattgt aatcttttaa tctctctgca
     8101 tttgaaacat gttgtcttcg aaaacgacgc tttaatttct tttgaaaaat ctcatgttca
     8161 gttatcaata aaatcttttc atctacaaaa tgaaaaccat gtctgagatt accctctatt
     8221 aaatttacag attctttaca gatacttgtc ttatctctag aatccaattt aatctgatat
     8281 tcctctaaca tatcctccaa tgttttactt cccattgaat tgctagactg cagaataatg
     8341 gtgtaatcca tttttttata tcgttcaatt tcttctttta gaaaagaaaa ctgattgaaa
     8401 aattcctgta taggatattg attgaattga taaattttgt caaatttgag atttcctaaa
     8461 cccttttgaa gattagagaa aaaggtcact ggactttgtt ttttatagat ttgttcaata
     8521 tcagaaaaat actgcatatc agaaaatgct ttactattct gtaattcttc tgtaaagtac
     8581 tgcgctaatt ctctttcaaa gacttcatac tgattcatca atttttgata atcatcaaag
     8641 aatattggag tatctttttc aatataatca aagacagtcc atgtcttatc atagcacaaa
     8701 gataaaaact tccgagaatc tgcatgactt tgtttttggt gaaaacttga aagaatttct
     8761 tctaggtatg atttcaaaat aggtgataaa gtttttgaaa tttgtttttc taaagctgac
     8821 tgtcctcgtt gataatcctt ttctctcaaa agcatatcac tagctggaaa gatagtgagt
     8881 tctgtcttat tttctttcga taattgtgtt tctacttcaa atgacctgat accatcaatt
     8941 tcatcaccaa aaaactcaat tcgacaaggt tctaactggg atatttcaaa aatatctaaa
     9001 atatctcctc gaagactaaa ttcgccctga gtttgtactt gagtaacttt ttgatagcca
     9061 ttttccttta actgatggat aaacgcgtgt tgagcatatt cttcaccaac tgagattttt
     9121 acaatactat ctttgaatgc attgggagac ggtaaaatca atcgacttgc tgcgatatta
     9181 caaactaaaa tccctttctt agatgaatca gtcaaaaaac gcaaggcttc aacccgtgaa
     9241 ataatttttt cctgtgaaga catcaaaaac tccaccatag gagcatcatc taccaaaaat
     9301 ggatagacga gttcctcacc caagatagaa ataagatcac taacaagtcc ttctgcttct
     9361 ccataagttg acgtcaataa cacaatccta tcttcttttt ctaaactgct tgcaattgca
     9421 agagccttag tagatgttga taaaccaagt attagttgtc ttttcttatc tgttaaattt
     9481 tgatgccatt ttttaatctg atcattttct gagaataaat ctaataaggt caccatttat
     9541 ccgttatacc tctgcattgt tttctcaaaa tttttctctt gtaaatagta ttttacagaa
     9601 tcgtcaactt tgtcaacaga ctgtaaaata ccgatataat catccctgtc aaacttactc
     9661 aaaacatgat gaacaactga cataccattt ttaggtcttc caattccaat cttaacacgg
     9721 ttaaagacct gagttcctat atgttgaata atagacttga taccattatg accacctgct
     9781 gagccttttg ctcttaaacg aattttccca acttccatgt caagatcatc gtaaatgata
     9841 agtaaatcgt caatatccaa accatagtaa gttaataaag catgaactgc ttttccactt
     9901 tcattcataa aggtcgttgg tttaaccaga taaatttttt ctccatttag gaaaaaggat
     9961 gctaggtcag cttgaaatat cttatcgtgt gtaaaagtga cattctgttt cttcgctagt
    10021 tgatcaatca acataaaacc aacattgtgt tttgtttcaa aatatttatc ccctggattt
    10081 cccaaaccta caagtaattt ggtcatttat ttttcctttc aaaagccaaa agggttggaa
    10141 tttttttcca acctaattga caccatttat taatttttag acattaaagc ggaattctat
    10201 gatgtcgcca tcttgaacga tatattcttt tccttcttca cgcaagcgtc cagcttcttt
    10261 tacggccttt tcagatccgt atttcactag atcttcatat gacatggtta ctgcacgaat
    10321 aaagcctttt tcaaagtctg agtggataat accagctgct tgaggagcct tcataccacg
    10381 tttgaaagtc caagcgcgaa cttctttttc accagctgtg aagtaagttc ccaatccaag
    10441 caagtggtaa gctgcacgcg tcaacttatc tacacctgat tctgtcaaac caatggcttc
    10501 aagaaactct tttttatctt catcatccaa ttcagaaatt tcttcctcag cacgcgcaga
    10561 aataacgact acttcagcat tttctgtcgc tgcaaattca cgaatttgtt tgacatagtc
    10621 gatagagtca ggttctgaaa ccacatcctc gtccacatta gctacataaa gaactggttt
    10681 agtcgtcaaa aggaaaagac ctttgacaac cttttgttcc tcatctgtaa attcaatggt
    10741 acgagctgat ttcccgtctt ctaggactgg tttaatcttt tgaagaacat tgaattctgc
    10801 tactgattct ttatcttttt gcgtacgtgc catcttttct acacgcgcat atcgtttgtt
    10861 cactgattct aagtcagcaa gaattaattc cagattaatt gtatcaatat ctgcaagtgg
    10921 atctacaaag gcgtcttcac gtccttgctc gcgcatcaca ttttcatcat caaaagcacg
    10981 aactacgtga acaatcgcat ctacttcacg aatattggcc aagaatttat tccctagccc
    11041 ttctcctttt gaagctcctt ttacaatccc tgcaatatcc gtaaattcaa atgttgtggg
    11101 aactgtcttt ttaggagtta tcatttcagt tagtttttgt aggcgttcat ctggaacttc
    11161 caccattcca acatttggat caatcgtcgc aaatgggtag tttgctgcct ctgctcctgc
    11221 ttttgtaatt gcattaaata gtgttgattt accaacgttt ggcaaaccaa cgatacctgc
    11281 tgtcaaagcc atatttctca ttctccgttt tcatttcaat ccctaatatt ataacacaaa
    11341 aagggataaa gtgctaaccc tctaactaag ggttctcagt caataatttt attcattttt
    11401 cgctcaaaat catatcgccc catcatgaca acatgctcac aattactgca ttttattttg
    11461 atatctgctc ctacacgtgt aatttcccaa cgattagcct ttttaccagt cgacttgatt
    11521 gtacaagcgt gtgatttttt catctcaaca aaatttccaa cttgatacat actactctcc
    11581 ttttcttttt cgattatatc ataaaagagg cgagccaggc tcaacctctt tcacttaatt
    11641 tgtacgaact ggtgtaatga gctgcatgaa gtcttcgtca gtatctgctg gcacaagagt
    11701 aaatggacga acagctgaga taaagctaat ggtcaccttt tcgctattta aagctttaag
    11761 agaatcaatc aagtaagttg ggttgaaact aatggtcaaa tcttcaccag taacctgatc
    11821 agtatcgatt tcttcgttta ctttaccaac ttctggagag tgaacatggg cgctaacaac
    11881 cccatcctta atttcaagtt tcacagtacc attttgagtc gcacttgata aaagacgggc
    11941 acgctccatt gactggcgta agtttaccac attaaaagta atagtagtgt taaagtctgt
    12001 tggaatcaag cgatctgtat caggatagtt tccttctagg agacgagtat agaagctaat
    12061 attttcgctt ctaaagagga tttggttatt ggcaaagaaa atctctacag tttcgatatc
    12121 atctgtaaat accgctgaaa attcgcgtag agaacggcta ggaattacga catcaaaatc
    12181 atcactattt ttttcaagag tcaatttttt ctggcttagg cgatgagagt ctgttgcaac
    12241 tgtttttaac tctttgtgtt gactcaatac gaagtggaca cctgttaaaa tcggacgact
    12301 ctcttgtgta cttgcagcaa aggctgtttc attaataatt ttcttgagta attttgtttc
    12361 aagtattaaa ggagtgcttg ctgaaatttc ttggattcgt ggatattgtt cgctatcttt
    12421 tccttttagg gtaatttctg atttgccact ggttaaaaca atttgatttt gttcaatttc
    12481 tttaaaatca agagttacat caggtaaact agatactaca ttgataaaga aagaagcttc
    12541 aagaaggatc gaacctaaag aagtaattaa caaaccagca tcttcatttt tttgagaaat
    12601 aaaattttca attgaaattt gaccatttga accaattaaa gtaatacctt cattggtcac
    12661 gtcaattttt actgttgata aaataggaat ggcattttta gaactaatag ctctcttagt
    12721 agtatttaat gcttgtagaa ataaattttt attaattgaa aaatgaatca tggattctcc
    12781 tttatttatt tttagtatta gaaagataat agtaataata gagtctgtga aatctgtgga
    12841 taacagcctt taaacaagtc atatcaagtt ttttagcttg tttaaaaaat gtggataaaa
    12901 aactaaaagt tatccacaaa ttatttgatt ttctttttga ttgattcaat ttctaaacgt
    12961 aaattatcgt cttgatcaat caaagatttt attttggcat gggcatgaat gactgtggta
    13021 tgatcttttc ccccaaattc cttcccaatt tttggaagac tattatctgt tagttctcta
    13081 gataaataca tggctacttg acgggccaaa acaatatttt gaaggcgtct acttcccttc
    13141 atttctttga tactaacacc ataaaagtta ccaacttcag tttggatttt atcaattggg
    13201 atgacgagca tttggctaac atcttgtttg cgggctctaa tggcttctgc agcaatatca
    13261 atagtgatat ccttgatttt ttttactctg gcaattaaag tgatgtcgtt gatggctccc
    13321 tcaagatctc gaacatttga atcaaattgc ccagctaggt attctagagt atcactttgg
    13381 aaattgtagc ctaaatgttc cgttttactt tgtaaaatgg caatacgtgt ttcaaagtca
    13441 gggggtgtga tagtttgtgt caatccccaa ctaaaacgcg tgacaagcct ctcctcgagc
    13501 ccttctagat gttttggact acgatcactc gttaggacaa tctgtttttg cttgtcatga
    13561 agggcgttaa aggtattgaa aaattcttcc tgagttgcga ctttttttcc gctgagtgac
    13621 tggatatcat cgattaacaa aagatcaaga ctacgatagg tctttttaaa cttttccatt
    13681 tccccaagtc ttaggtgatc aagaaagtca ttaataaagc tttcggcagg gatatattta
    13741 acacgcgcat taggaatatt ttttagaatt tcatttccaa tagcgtttaa taagtgagtc
    13801 ttaccaaggc ctggtcctcc atagataaaa agagggttat aggtcagagc caaatcttca
    13861 gagacagcta aagcggctga cacagcccaa acatttccat ccccttgaat aaagttatca
    13921 aaggtatact tttcttttaa tcccgtatct gaataaggaa tagatactaa ctttggacta
    13981 tagttataaa gagttaaatt tgtagcttct tcaacttgtg agctagtcgt atcttgaggt
    14041 ttggtgaaaa tatagtgggg agttatttca gcgtcataaa tttcaaaacc agctactaca
    14101 ataatatctt ttagttgttt ttcccagacc atttccattt cagagcgagg tagaaatata
    14161 gtggcaacat tttcctctac cttgatgagt tcagcttgaa tagcatagaa atcatacatg
    14221 gatcgagtca gtctttcttg tgcaaattct aatatacgat tccaaaattg tttttctttc
    14281 aatcctttct cctcctttac tatttaaaag tttaatacta gagatatttt accatagata
    14341 gcaagaattt tccacaagct gtgaaaaata atccacaatg ttaccaaact ttatccacag
    14401 gttggggata aaagaagaaa ttattgattt attaagcttt ttattgaaaa acatagtgga
    14461 taaccttgtg agataaaaaa ataaaagaac agccttattt caggctgttg ataattctac
    14521 tatattcttc ttgatttgaa aaagaaataa tgatttttcc actgtctttt ttagatagtt
    14581 taatttctac atctaatccg agtagttttc ttaactgttt ttcttcattt tgtatgaaat
    14641 gattagtttt ttgctgtttc ttttgttttt tctctgtcag aagagcttct aatttcctta
    14701 cagaaatatc ttcttctata atccgttgaa agaaatagtc ttgttgttcc ttatttaacc
    14761 caactaggga acgcgcatgg gcttgtgata gtttgccatt ttctacttct gaaagaatct
    14821 gttctggcaa ggaaagtaaa cgaatggagt tgctgatata tggacgagac ttgcccatct
    14881 tatctgcaat ttcagcatgg gtgaatcctt tctctacgag agattcatag gcgcgtgctt
    14941 cttctattgg gtttaaattt tctctctgta aattttcaat aatggactgg accatcatct
    15001 cttggtctga aatctgttta acaacagctg ggatagaccg tagaccagct aaaagtgaag
    15061 cccgatagcg tctctctcct gcaaggattt cataaccaat aacaggagat tgacgaacaa
    15121 taatcggttg aatgacccca ttttctttga tagactgtgc tagttcatct agtttttctc
    15181 tatcaaattc ttttcggggt tgatagggat ttttttgtat atctgtgata gaaatcattt
    15241 caaatttttc catgattcta cactaacaca tcttttctct tatgtaaagc tttctttaca
    15301 tagatgtcaa ttaagattct aaatcacctg aactcttgtt aagtttgata gaggtagttt
    15361 cttctttccc gttacgatag taggttatct taatggtgtc tccgatagaa tggttgtaaa
    15421 gagcactttg taagtctgtt gatgaagcaa tctctttgtc atctactttt gtaattacat
    15481 cgtatttttc aaggtgacca ttggcaggca tattactttg taccgaacga acaactacac
    15541 cagatgtaac attacttgga atattgagtc ttctgatgtc gcttgtactc acattagata
    15601 aattaaccat ctggattccc aaagctggac gcgtcacttt tccgtttttt tctaactgtt
    15661 caataatatt gatagcatca tttgcaggaa ttgcgaaacc aagaccttct acagatgttc
    15721 ctccatttgt agcaatttta cttgaggtaa ttccgataac ctgcccttga atattgatca
    15781 gtgggccgcc agagttacct gggttaatag cagtatcagt ttggatggct tttgtagaaa
    15841 tagcttgtcc atcttccgat tttaaggata catttctatt gagactggat acgatacctt
    15901 gagtgacagt atttgcatat tcagaaccta acgggctacc gatggcaata gcagtttctc
    15961 ctacagttaa cttactagaa tcaccaaact cagctactgt tgtcactttt tctgaagaga
    16021 tttttacgac agcaatatca gagaaagtgt cagctccgac aatttctcca ggtactttag
    16081 tcccatctga caatcgaata tctactttgc tggcgccatt tataacgtga ttgttggtga
    16141 cgatgtaagc ttctttatca ttctttttat aaataactcc agatccttca ctagagattc
    16201 gctgagaatc tgtgtcagta tcatcattgc caaatacgct attttgtctg tttgccgaat
    16261 aagtaataac agaaacaaca gcatctttta ctttgttaac agcctgtgtt gttgaatttt
    16321 cgttcttata ggcagtttgt gtaatagtac tattgttgtt agagttgttt acactacttt
    16381 tttgagttag ttgagttatt gaaaaactac ccaaggctcc actaaaaaag ctaatgacga
    16441 taacgactaa taattgaaac cattttttgt aaaatgtttt tagatgtttc atatttgcct
    16501 ccatatgttt gaattactga aagtataaac tgactagctt aattataact taaacacaaa
    16561 agttttacac aaactgtgga taactctttt gaaactgtga ttttcttaat tgaaatctat
    16621 tttttatttt gtgaataaga tgtgaaaaaa tagagaatat gttagaatag agtcatgaaa
    16681 attaaagttg taacagttgg gaaactgaaa gaaaagtatt taaaagatgg tatcgcagag
    16741 tattcaaaac gaatttctag atttgctaag tttgaaatga ttgagttatc agatgaaaaa
    16801 acaccagata aggccagtga atcagaaaat caaaagattt tagaaataga aggtcagaga
    16861 attttatcaa aaattgctga ccgtgatttc gttattgtgt tagccattga agggaaaact
    16921 ttcttctcag aagaatttag taagcagtta gaagaaactt ctataaaagg attttctact
    16981 cttactttta ttattggggg aagtttagga ttgtcatcat ctgtaaaaaa tagagccaat
    17041 ctttctgtca gttttggtcg cctaacctta ccccatcagt taatgagact agttcttgtt
    17101 gaacaaatct atcgcgcttt tacgattcag cagggattcc cctaccataa atagaaaatt
    17161 gacttttaat tgaatttttg gtagaataat tgtattaggt ctcatagctc agctggatag
    17221 agcattcgcc ttctaagcga acggtcgcag gttcgaatcc tgctgggatc aatataatag
    17281 caaagctggg aattttcccg gcttttttct taaaaaagta cactttggga gaaaaaaatg
    17341 acagttgaga gaattttatc taaaacgaaa ttccattttg tataatggtt tttgtaagtt
    17401 agcttacaag aaaaaacatt ttaggagatt ttattatgaa aaacacagtt aaattggaac
    17461 agtttgtagc tttgaaggaa aaagacttac aaaagattaa aggtggggag atgaggttgt
    17521 caaaattctt ccgtgatttt attttacaaa gaaaaaagta atgaaataag gggaaagagt
    17581 aatggattta tttggatttg ggacggttat tgttcatttt ttaattatta gtcacagtta
    17641 ccattttatt tgtaaaggtc aaataaatag aaaagaatta ttcgtttttg gtgcttatac
    17701 attactaaca gaaatagtat ttgattttcc cttatatatt ctatatttag atgggttagg
    17761 gattgaaaga tttttatttc ctttgggatt atattcctat tttcgatgga tgaaacagta
    17821 tgagagggat agaggactat tcctaagttt actactatct cttttatatg agagcactca
    17881 taactttctg tccgtaactt tctcctctat aacaggagat aattttgttt tacaatatca
    17941 tttcccattc tttttcgttg tgacggtgtt aacctatttt gttacattaa aaatcattta
    18001 ctatttccat ttggaactag cctattttga cgaggactac ctttatcctt tcttgaaaaa
    18061 agtatttttt gctttactat tgctacatat tgtatctttc gtttcagata tggtaagtac
    18121 gattaaacat ttgaatagtt ttggaagtat tttgtcatct attgtcttta tctctctcct
    18181 tttgaccttc tttgcaatga attctcataa agttcaaatg gagaaagaga ttgctttgaa
    18241 gcagaagaaa tttgaacaga aacatttaca gaattacaca gatgaaattg ttggtctgta
    18301 taatgaaatc cgtggttttc gacatgatta tgctggaatg cttgtcagca tgcagatggc
    18361 aattgacagt ggtaatttac aggaaattga cagaatttac aatgaagttt tagtcaaagc
    18421 aaatcataaa ttgcgttcag ataagtacac ttactttgat ttgaacaaca tagaagactc
    18481 agctttacga agtttggttg ctcagtcaat tgtctatgct cgaaataatg gtgtagagtt
    18541 tacactggaa gtaaaagata cgattaccaa gcttccaatt gaactattgg atttggttcg
    18601 tatcatgagc gttttattga ataatgctgt cgaaggatcg gctgatagct ataaaaagca
    18661 gatggaagta gcagttatta agatggaaac tgaaacagtt attgtgattc agaattcatg
    18721 taaaatgacg atgactcctt caggagatct atttgcctta ggattctcca ctaagggaag
    18781 aaatcgcgga gtcggattaa ataatgtgaa agaactacta gataagtaca acaatattat
    18841 tttagaaaca gagatggaag gcagtacatt tagacaaatc attagattta agagggaatt
    18901 tgaatgaaag ttttaatttt agaagatgtt attgaacatc aagtgagact agagagaata
    18961 ttggatgaaa tttcgaaaga atcgaatatt ccaatatcat acaagacaac gggaaaagtc
    19021 cgtgaatttg aagaatacat tgaaaatgat gaagtaaatc agctttattt cctagatatc
    19081 gatattcatg gaattgagaa aaagggattt gaagtggctc agctcattcg tcattacaat
    19141 ccttacgcta ttatcgtctt tatcactagt cgatcagagt ttgcgactct aacctataaa
    19201 taccaggtat cagccctaga ttttgttgat aaggatatca atgatgagat gtttaagaag
    19261 agaattgagc aaaatatctt ctacacgaag agtatgttac ttgaaaatga agatgttgta
    19321 gattatttcg actacaatta caagggaaat gatttaaaaa ttccttacca tgatattttg
    19381 tatattgaaa caacaggggt ctctcataaa ttgcgcatta ttggtaagaa ttttgcaaaa
    19441 gagttttatg gtaccatgac agatattcag gaaaaggaca aacatactca gcgattttat
    19501 tctcctcaca agtcattttt ggtaaatata ggcaatatca gagaaattga tcgaaaaaac
    19561 ttagaaattg ttttctatga agaccatcgt tgtcctattt caagattaaa aattagaaaa
    19621 ttaaaagata ttttagagaa aaaatctcaa aagtgattga caattagcaa gaaattgata
    19681 taatggttat atctgctaca gatagaaggt ccgttggtca aggggttaag acaccgcctt
    19741 ttcacggcgg taacacgggt tcgaatcccg tacggactat tttatccgcc atagctcagt
    19801 tggtagtagc gcatgactgt taatcatgat gtcgtaggtt cgagtcctac tggcggagta
    19861 tagataaaag ggaacacagc tgtgttcctc tttttgtatc aatttgtatc accaagcatt
    19921 ttcataagga agtctgttat ttcttgagaa ctttcttttt ttccatgtgc aatccaagtt
    19981 tggcagacac caaaaagtgc atgagttaga tagatgctac tatattctaa ttcggtggta
    20041 tttagattca gttgcataaa tcgcttttgt aaatctgtac taagcatgat atgaagttta
    20101 tttcgtaaga aattttggat ttctttagtc ccattttcag aaagaagggc agccagaagt
    20161 ggttctgact ctagatattc aaaaacttct aaaatagcgt ctcttttgtg atgagcatgt
    20221 ttttgaaaaa tatattcaaa tgtatggaat agcttgcttt gatagtgctc aatcatatca
    20281 tacttatcct tatagtgagt atagaagctg gaacgactaa ttccggcttt ttctactaat
    20341 ttgacagtag aaattttatc aaatggctgt tccatcagta attgtaccat agcattttca
    20401 atagttcgct ttgtttttaa gcgtttgtta ctttcttgca tatttcctcc ttgtaaacaa
    20461 attagactat atgtttaaaa atagattttt tatcttgtaa tttagatttt ttaatgtata
    20521 atctattata tcaaaatttt agacaatatg tttaaaaaag gagaaactaa gtttaaagaa
    20581 tggaaagcaa tttaaaaaaa accaaccttt attattgtca tgatcgggat ttctcttatt
    20641 ccagatctgt acaatatcat atttttgtca tcaatgtggg atccatatgg gcaattgtct
    20701 gacttacctg tggcagttgt aaataatgat aaagaggctt cctataatgg taatactatg
    20761 gcaataggaa aagacatggt gtccaattta aaagaaaata aaaccttgga ttttcatttt
    20821 gtagatgaag aggaaggaaa gaagggattg gaagatggcg attactatat ggtagtgact
    20881 ttaccaagtg atttatctga aaaaacaact acattatcca atattcaatc gacagcagct
    20941 tatcaatcat tgacaagtga gcaacaaact gagataagtg attctgtatc tcaaaattca
    21001 actgatagta ttcaatcggc tcagtcaatt gtagctttag tacaagattt acagggaagt
    21061 ttagaaaact tacaaaatca atcttctaat ctttcgactt taaaaaatca atctaatcaa
    21121 gtatcaccta ttacttctac ttctttgata ggattgtcaa gtggattaac agagatacaa
    21181 ggagatgtta ctagcaaatt agttcctgcc agtcagtcga ttgcatcagg tgtaaacgca
    21241 tatactacag gtgttgataa agtttctcag ggcgcaagtc aactaagtga aaaaaatgcc
    21301 accttgacag gtagtttgga taaactagtt tcaggctcaa acaccttgac acaaaaatct
    21361 tctagattga cagcaggagt tggttaatta caatcaggat ctgggcaatt agcagacaaa
    21421 tccagtcagt tactttcagg tgcttctcca ttagagaata gagctaataa attggcagat
    21481 ggatctggga aactagcaga aggtggaaca aagttaactt ctggattgga agatttacag
    21541 acaggacttg cttctttagg acaaggacta ggtaatgcta gtgatcaact caaatcagta
    21601 tcaacagaat ctaaaaatgc agagattttg tcaaatccac tcaatctttc aaaaacagac
    21661 aatgatcaag ttcctgtaaa tggaatcgca atagctcctt atatgatatc agttgctctt
    21721 tttgttgcag caatatcaac aaatatgata tttgcgaaat tgccttcagg acgtcatcca
    21781 gagagccgtt gggcttggtt gaaatctcga gctgaaataa atggtattat agctgttttg
    21841 gcaggaattt tggtatatgg aggagttcag cttattggtt taactgctaa tcatgagatg
    21901 agaatattta ttctcatcat cctaacaagt ttagtattca tgtctatggt gaccacttta
    21961 acaacgtgga atagccgtat aggagctttt ttcttactta ttttgctttt actacagtta
    22021 gcatcaagtg caggtactta tccacttgct ttgacaaatg atttctttag atctattaat
    22081 ccctggttac caatgagcta ttcagtttcg ggattacgac aaacaatctc tatcaacaag
    22141 tcattttcct agctgtcata ctagctctat ttactggttt aggtatgcta gcctatcaac
    22201 ataagaaaat ggaagaagat taaaaaaatc gaccgattaa tgaactgcac cccaaaagtt
    22261 agacagaaaa aatctaactt ttgaggt
//
LOCUS       DAVBEO010000035        22104 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 009
            SAMEA1678075-rid20185393.denovo.035, whole genome shotgun sequence.
ACCESSION   DAVBEO010000035 DAVBEO010000000
VERSION     DAVBEO010000035.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678075
            Sequence Read Archive: ERR226392
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 22104)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22104)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980207.1
            Genome Coverage       :: 150x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:50:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 72 of 147
            Pseudo Genes (incomplete)         :: 72 of 147
            Pseudo Genes (internal stop)      :: 42 of 147
            Pseudo Genes (multiple problems)  :: 32 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22104
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678075-rid20185393.denovo.035"
                     /strain="KS 009"
                     /db_xref="taxon:1313"
     gene            complement(<1..389)
                     /locus_tag="VQ543_001385"
     CDS             complement(<1..389)
                     /locus_tag="VQ543_001385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000846948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="immunity protein"
                     /protein_id="HET2612101.1"
                     /translation="MKTFFAKKRNIFLARLFLGQLPLLVSTYLFLSRQFLNFSVVFQF
                     LLVVINLASILVTVYLTREMRIREFEDDDLVSPRTNQLMFIGLTGFMSIICLYRGITA
                     GESYQQIIAYIGAVLCLIIMLLLMWGL"
     gene            complement(386..550)
                     /locus_tag="VQ543_001386"
     CDS             complement(386..550)
                     /locus_tag="VQ543_001386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000727119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2612102.1"
                     /translation="MKKKILIIFVLYLIMSIFLYPLRESAWYQLFYTIAYVIAVMIYF
                     AINKKKGEKK"
     gene            complement(849..968)
                     /locus_tag="VQ543_001387"
     CDS             complement(849..968)
                     /locus_tag="VQ543_001387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin"
                     /protein_id="HET2612103.1"
                     /translation="MDFKSFIIGLVVGIFGPYMYNLIRKIFSKFPKKDTDSTP"
     gene            complement(971..1201)
                     /gene="blpU"
                     /locus_tag="VQ543_001388"
     CDS             complement(971..1201)
                     /gene="blpU"
                     /locus_tag="VQ543_001388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpU"
                     /protein_id="HET2612104.1"
                     /translation="MDTKMMSQFSVMDTEMLACVEGGGCNWGDFAKAGVGGAAARGLQ
                     LGIKTGTWQGAATGAAGGAILGGVAYAATCWW"
     gene            complement(1270..1539)
                     /gene="blpJ"
                     /locus_tag="VQ543_001389"
     CDS             complement(1270..1539)
                     /gene="blpJ"
                     /locus_tag="VQ543_001389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpJ"
                     /protein_id="HET2612105.1"
                     /translation="MNTKMLSQLEVMDTEMLAKVEGGYSSTDCQNALITGVTTGIITG
                     GTGAGLATLGVAGLAGAFVGAHIGAIGGGLTCLGGMVGDKLGLSW"
     gene            complement(2006..2203)
                     /gene="blpI"
                     /locus_tag="VQ543_001390"
     CDS             complement(2006..2203)
                     /gene="blpI"
                     /locus_tag="VQ543_001390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpI"
                     /protein_id="HET2612106.1"
                     /translation="MNTKMMEQFSVMDNEELEIVSGGRGNLGSAIGGCIGAVLLAAAT
                     GPITGGAATLICVGSGIMSSL"
     gene            2485..3072
                     /locus_tag="VQ543_001391"
     CDS             2485..3072
                     /locus_tag="VQ543_001391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase C39"
                     /protein_id="HET2612107.1"
                     /translation="MTSYKRTFVPQIDARDCGVAALASIAKFYGSDFSLAHLRELAKT
                     NKEGTTALGIVKAADEMGFETRPVQADKTLFDMSDVPYPFIVHVNKEGKLQHYYVVYQ
                     TKKDYLIIGDPDPSVKITKMSKERFFYEWTGVAIFLATKPSYQPHKDKKNGLLSKLPS
                     SDFQTKISHCLHCSLKLIGHYYQYRWFLLSPRNLG"
     gene            3065..4654
                     /locus_tag="VQ543_001392"
                     /pseudo
     CDS             3065..4654
                     /locus_tag="VQ543_001392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864064.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="peptide cleavage/export ABC transporter"
     gene            4665..6026
                     /locus_tag="VQ543_001393"
     CDS             4665..6026
                     /locus_tag="VQ543_001393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001069090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin secretion accessory protein"
                     /protein_id="HET2612108.1"
                     /translation="MNPNLFRSVEFYQRRYHNYATVLIIPLSLLFTFILIFSLVATKE
                     ITVTSQGEIAPTSVIASIQSTSDNPILANHLVANQVVEKGDLLIKYSETMDESQKTAL
                     ETQLQRLEKQKEGLGILKQSLEKATDLFSGEDEFGYHNTFMNFTKQSHDIELGITKTN
                     TEVSNQANLANSSSSAIEQEITKVQQQIGEYQELRDAIINNRARLPTGNPHQSILNRY
                     LIASQGQTQGTAEEPFLSQINQSIASLESSIASLKIQQAGIGSVATYDNSLATKIEVL
                     RTQFLQTASQQQLTVENQLTELKVQLDQATQRLENNTLTAPSKGIVHLNSEFEGKNRI
                     PTGTEIAQIFPVITDTREVLITYYVSSDYLLLLDKGQTVRLKLEKIGNHGTTIIGQLQ
                     SIDQTPTRTEQGNLFKLTALAKLSNEDSKLIQYGLQGRVTSVTTKKTYFDYFKDKILT
                     HSD"
     gene            6083..6238
                     /gene="blpC"
                     /locus_tag="VQ543_001394"
     CDS             6083..6238
                     /gene="blpC"
                     /locus_tag="VQ543_001394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quorum-sensing system pheromone BlpC"
                     /protein_id="HET2612109.1"
                     /translation="MDKKQNLTSFQELTTTELNQIIGGGWWEDFLYRFNIIEQKNTKG
                     FHQPIQL"
     gene            complement(6282..7622)
                     /locus_tag="VQ543_001395"
     CDS             complement(6282..7622)
                     /locus_tag="VQ543_001395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001099894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HET2612110.1"
                     /translation="MNVAWILLYTLVTHGLKIVIFFKVDGISLTFERIFKAFLFKILL
                     AVVFGMLGYMVGNTYLSYFMEPLYGIGLSFLLLRELPKKLLLFYGLFPMILVNLFYRG
                     VSYFVLPFLGQGQVYDDYSFIWLCIIIFNFFISLAFLKWLDYDFTSLRKGILDKDFQK
                     SLTQINWIMGAYYLVIQNLSYFEYEQGIQSTTVRHLILVFYLLFFMGIIKKLDTYLKD
                     KLHERLNQEQDLRYREMERYSRHIEELYKEVRSFRHDYTNLLTSLRLGIEEEDMEQIK
                     EIYDSVLKDSSEKLQDNKYDLGRLVNIRDKALKSLLAGKFLKARDKNIVFNVEVPEEI
                     QVEGMSLLDFLTVVSILCDNAIEASVEACQPHVSIAFLKNGAQETFIIENSIKEEGID
                     ISEIFSFGASSKGEERGVGLYTVMKIVESHPNTSLNTTCQDHVFRQVLTVIHIE"
     gene            complement(7636..8373)
                     /locus_tag="VQ543_001396"
     CDS             complement(7636..8373)
                     /locus_tag="VQ543_001396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001219153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET2612111.1"
                     /translation="MRIFVLEDDFSQQTRIETTIEKLLKEHHITPSSFEVFGKPDQLL
                     AEVHEKGAHQLFFLDIEIRNEEMKGLEVARKIRDRDPYALIVFVTTHSEFMPLSFRYQ
                     VSALDYIDKALSAEEFESRIETALLYANGQDSKSLAEDCFYFKSKFAQFQYPFKEVYY
                     LETSTRPHRVILYTKTDRLEFTASLEEVLKQEPRLLQCHRSFLINPANVVHLDKKEKL
                     LFFPNGGSCLIARYKVREVSEAINNLH"
     gene            complement(8378..8716)
                     /locus_tag="VQ543_001397"
     CDS             complement(8378..8716)
                     /locus_tag="VQ543_001397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000682119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET2612112.1"
                     /translation="MKHMIIQTQKTVYKVNVDDIYYIQTHPTKAHTVQIVTEEASFNM
                     LQNLSNLENQYGETLMRCHRNCLVNLDKLKSIDFQERILFLGEEGQYAVKYARRRYRE
                     IRQKWLKEGE"
     gene            8993..9322
                     /locus_tag="VQ543_001398"
     CDS             8993..9322
                     /locus_tag="VQ543_001398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase BlpT"
                     /protein_id="HET2612113.1"
                     /translation="MTDTDPIKRAHTLITDLNKAYQACKQASADDVRFQEQLNSILGF
                     LAKAETVDNRFLIELEKFYQTSSLLMGLSALDPDAPTRAAWRAYDRFHFDQVKTKLIL
                     NENQRAN"
     gene            complement(9490..10539)
                     /locus_tag="VQ543_001399"
     CDS             complement(9490..10539)
                     /locus_tag="VQ543_001399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET2612114.1"
                     /translation="MKDLFLKRKQAFRKECLCYLRYVLNDHFVLFLLVLLGFLAYQYS
                     QLLQHFPENHWPILLFVGITSVLLLLWGGIATYMEAPDKLFLLVGEEAIKLHLKRQTG
                     ISLVFWLFVQTLFLLLFAPLFLAMGYGLPVFLLYVLLLGVGKYFHFRQKASKFFTETG
                     LDWDYVISQESKRKQVLLRFFALFTQVKGISNSVKRRAYLDFILKAVQKVPGKIWQNL
                     YLRSYLRNGDLFALSLRLLLLSVLAQVFIEQAWIATAVVVLFNYLLLFQLLALYHAFD
                     YQYLTQLFPLDKGQKEKGLQEVVRGLTSFVLLVELVVGLITFQEKLALLALLGAGLVL
                     LVLYLPYQVKRQMQD"
     gene            complement(10536..11267)
                     /locus_tag="VQ543_001400"
     CDS             complement(10536..11267)
                     /locus_tag="VQ543_001400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000889926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2612115.1"
                     /translation="MLEIKNLTGGYVHVPVLKDVSFTVESGQLVGLIGLNGAGKSTTI
                     NEIIGLLAPYSGSININGLTLQGDATSYRKQIGYIPETPSLYEELTLREHIETVAMAY
                     GIEQKVAFERVEPLLKMFRLEQKLDWFPVHFSKGMKQKVMIICAFVVDPSLFIVDEPF
                     LGLDPLAISDLIQLLEVEKQKGKSILMSTHVLDSAEKMCDAFVILHKGEVRAKGNLLQ
                     LREAFDMPEASLNDIYLALTKEEDL"
     gene            11335..11745
                     /locus_tag="VQ543_001401"
     CDS             11335..11745
                     /locus_tag="VQ543_001401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HET2612116.1"
                     /translation="MSDCIFCKIIAGEIPASKVYEDEQVLAFLDISQVTLGHTLVVPK
                     EHYRNLLEMNATSASQLFAQVPKVAQKVMKVTKAAGMNIISNCEEVAGQTVFHTHVHL
                     VPRYSADDDLKIDFIAHEPDFDKLAQVAETIKNA"
     gene            11755..12042
                     /locus_tag="VQ543_001402"
     CDS             11755..12042
                     /locus_tag="VQ543_001402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2612117.1"
                     /translation="MKLSNLLLFAGAAAGSYLVTKNRQTITDEVLNTTDRVQAIKDDV
                     DIIQNSLQIIDQQKELIKEYQEDLTYKFKVLEKDIQTRLAVIKEMQGTEDK"
     gene            12204..12443
                     /locus_tag="VQ543_001403"
     CDS             12204..12443
                     /locus_tag="VQ543_001403"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2612118.1"
                     /translation="MHHNLGNSYSIKIKKQTRKLGTDCSKHRFKVVDRTDEVSSKHCF
                     EVVDRTDEVSNHTHDKPTLTWFEEIFEEYHSPFHN"
     gene            complement(12793..13929)
                     /gene="dnaJ"
                     /locus_tag="VQ543_001404"
     CDS             complement(12793..13929)
                     /gene="dnaJ"
                     /locus_tag="VQ543_001404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001066288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaJ"
                     /protein_id="HET2612119.1"
                     /translation="MNNTEFYDRLGVSKNASADEIKKAYRKLSKKYHPDINKEPGAED
                     KYKEVQEAYETLSDDQKRAAYDQYGAAGANGGFGGAGGFGGFNGAGGFGGFEDIFSSF
                     FGGGGSSRNPNAPRQGDDLQYRVNLTFEEAIFGTEKEVKYHREAGCRTCNGSGAKPGT
                     SPVTCGRCHGAGVINVDTQTPLGMMRRQVTCDVCHGRGKEIKYPCTTCHGTGHEKQAH
                     SVHVKIPAGVETGQQIRLAGQGEAGFNGGPYGDLYVVVSVEASDKFEREGTTIFYNLN
                     LNFVQAALGDTVDIPTVHGDVELVIPEGTQTGKKFRLRSKGAPSLRGGAVGDQYVTVN
                     VVTPTGLNDRQKVALKEFAAAGDLKVNPKKKGFFDHIKDAFDGE"
     gene            complement(14134..14487)
                     /locus_tag="VQ543_001405"
     CDS             complement(14134..14487)
                     /locus_tag="VQ543_001405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000115730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2612120.1"
                     /translation="MSVNKNNLSDIADYHEKIKFFEELFNLDYNPTEMLVTVERNGNV
                     IYKEFTEVAVGKSKYDHTSVFKDVMIYFSDHICQELHLYKTQDPHYNKFEFDLAKRSL
                     KITTRDNTTIFISNE"
     gene            complement(14500..16323)
                     /gene="dnaK"
                     /locus_tag="VQ543_001406"
     CDS             complement(14500..16323)
                     /gene="dnaK"
                     /locus_tag="VQ543_001406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002946936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaK"
                     /protein_id="HET2612121.1"
                     /translation="MSKIIGIDLGTTNSAVAVLEGTESKIIANPEGNRTTPSVVSFKN
                     GEIIVGDAAKRQAVTNPDTVISIKSKMGTSEKVSANGKEYTPQEISAMILQYLKGYAE
                     DYLGEKVTKAVITVPAYFNDAQRQATKDAGKIAGLEVERIVNEPTAAALAYGLDKTDK
                     EEKILVFDLGGGTFDVSILELGDGVFDVLSTAGDNKLGGDDFDQKIIDHLVAEFKKEN
                     GIDLSTDKMAMQRLKDAAEKAKKDLSGVTSTQISLPFITAGEAGPLHLEMTLTRAKFD
                     DLTRDLVERTKVPVRQALSDAGLSLSEIDEVILVGGSTRIPAVVEAVKAETGKEPNKS
                     VNPDEVVAMGAAIQGGVITGDVKDVVLLDVTPLSLGIETMGGVFTKLIDRNTTIPTSK
                     SQVFSTAADNQPAVDIHVLQGERPMAADNKTLGRFQLTDIPAAPRGIPQIEVTFDIDK
                     NGIVSVKAKDLGTQKEQTIVIQSNSGLTDEEIDRMMKDAEANAEADKKRKEEVDLRNE
                     VDQAIFATEKTIKETEGKGFDAERDAAQAALDDLKKAQEDNNLDDMKAKLEALNEKAQ
                     GLAVKLYEQAAAAQQAQEGAEGAQATGNAGDDVVDGEFTEK"
     gene            complement(16803..17327)
                     /gene="grpE"
                     /locus_tag="VQ543_001407"
     CDS             complement(16803..17327)
                     /gene="grpE"
                     /locus_tag="VQ543_001407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000046028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide exchange factor GrpE"
                     /protein_id="HET2612122.1"
                     /translation="MAQDIKNEEVEEVQEEEVVETAEETTPEKSELDLANERADEFEN
                     KYLRAHAEMQNIQRRANEERQNLQRYRSQDLAKAILPSLDNLERALAVEGLTDDVKKG
                     LGMVQESLIHALKEEGIEEIAADGEFDHNYHMAIQTLPADDEHPVDTIAQVFQKGYKL
                     HDRILRPAMVVVYN"
     gene            complement(17354..18388)
                     /gene="hrcA"
                     /locus_tag="VQ543_001408"
     CDS             complement(17354..18388)
                     /gene="hrcA"
                     /locus_tag="VQ543_001408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heat-inducible transcriptional repressor HrcA"
                     /protein_id="HET2612123.1"
                     /translation="MVTERQQDILNLIIDIFTKTHEPVGSKALQESINSSSATIRNDM
                     AELEKQGLLEKAHTSSGRMPSVAGFQYYVKHSLDFHRLAENEVYEIVKAFDQEFFKLE
                     DILQEAANLLTGLSGCTVVALDVEPSRQRLTAFDIVVLGQHTALAVFTLDESRTVTSQ
                     FLIPRNFLQEDLLKLKSIIQERFLGHTVLDIHYKIRTEIPQIIQRYFTTTDNVIDLFE
                     HIFKEMFNENIVMAGKVNLLNFANLEAYQFFDQPQKVALEIREGLREDQMQNVRVADG
                     QESCLADLAVISSKFLIPYRGVGILAIIGPVNLDYQQLINQVNVVNRVLTMKLTDFYR
                     YLSSNHYEVH"
     gene            complement(18552..19061)
                     /locus_tag="VQ543_001409"
     CDS             complement(18552..19061)
                     /locus_tag="VQ543_001409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001088691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2812 domain-containing protein"
                     /protein_id="HET2612124.1"
                     /translation="MNSRVEFRIFTIVDLDKEEEYLHEMHLKGWRYRTSRFGLFYFDQ
                     CQPDDVIYRIYDSRFLKKYKHELQDFRDRGWELIGAGSCSILRKSSSDLLPEDQVYMS
                     KGLKWEVMRSRLRSCTTTFLGGLVVCTSLFREDLSMSFFLIFVLYAFLISYLIHGYFR
                     LKRKYRVDE"
     gene            19669..21606
                     /locus_tag="VQ543_001410"
                     /pseudo
     CDS             19669..21606
                     /locus_tag="VQ543_001410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399214.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
     gene            21604..22104
                     /locus_tag="VQ543_001411"
                     /pseudo
     CDS             21604..22104
                     /locus_tag="VQ543_001411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001819352.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
BASE COUNT         6993 a         4580 c         3952 g         6579 t
ORIGIN      
        1 ttcaagcccc acatgagcag aagcatgatg attaagcaga gaacagcgcc aatataagcg
       61 attatttgtt ggtaggattc tcctgctgtg atacctctat acaaacaaat aatagacata
      121 aaacctgtca agccgatgaa cataagttga ttggttctag gactaaccaa atcatcatct
      181 tcaaactctc ttatcctcat ttccctagtg agataaacag taaccaaaat agaagccaag
      241 ttaataacta ctaaaagaaa ttggaaaact acggaaaaat ttaaaaactg acgagataga
      301 aatagataag tagaaacaag caagggcaac tgacctaaga acaatctcgc aaggaagatg
      361 ttccgttttt tagcaaaaaa agttttcatt tcttttctcc tttcttttta ttgatagcaa
      421 aatagatcat aactgcaatc acataggcta tggtataaaa tagctgatac caagcactct
      481 ccctaagcgg atatagaaag atggacatga ttagatacag aacgaaaata atcagtattt
      541 ttttcttcat aagatttcct cctaaatgtg cgatttatct tagttgagca agaacattta
      601 cactgctagt atagcactta ttttgacctt ggatcactca aatcataaat ggtcatcgaa
      661 acatcttgaa ttgttaaaaa atttaaaaag taagcattaa aaacatactt tcctctttat
      721 attgtattga taccaacttg tttgtagact tttcatcctg ctatcacata tcattttgac
      781 aggcgaaaca aaattaaaga aactcccctg taaattaagc tagcaaatac aggggagaaa
      841 tttatttttt agggggtact atctgtatcc tttttgggaa attttgaaaa tatttttcta
      901 attaaattat acatataagg accaaatata ccaactacta aaccaataat aaaactttta
      961 aaatccataa ttaccaccaa catgttgctg cataggctac acctccaagt atagctccac
     1021 ccgcagcacc agttgctgca ccttgccatg ttcctgtttt aatgcctagt tgaagacctc
     1081 ttgctgctgc tcctccaaca cctgctttgg caaaatctcc ccaattgcat ccgccacctt
     1141 caacgcaagc aagcatttca gtatccataa cagaaaattg tgacatcatt tttgtatcca
     1201 tgacaaatac tcctttttta aaaaactaaa ataaatcaga atagaatcct cataatttta
     1261 ctataagtct taccaactta gtcccaattt atcaccaacc atacctccta agcatgttaa
     1321 tccaccccca attgcaccaa tgtgtgctcc aacaaatgca ccagcaagtc cagctactcc
     1381 taaagtggcc aaacctgctc cagttccacc agttataatt cccgtagtga ctcctgtaat
     1441 cagtgcattt tgacaatcag tggagctata ccccccttca actttcgcaa gcatttcagt
     1501 atccataacc tctaactgtg acaacatttt tgtattcatg atgaatacct cctttttatt
     1561 ttcaatttgt taccaaagtc ttaaattcaa taaacaaata gattttttat agtatctttt
     1621 tgattttctt aaaaaagtat atacgtctac tatcttctta aaggtagcag tacctatttt
     1681 ttagtctaag atttcaataa tcttgagtat ctaaaatatc ttaatttcgt tattctcctt
     1741 gcaataaaaa gttttactat actatttatt aacttgcaga aagcaaaaaa tattagtaaa
     1801 taatagttta tagttaagtt ttttattcct accaatccat caactaagta aagcatcaac
     1861 gattacataa acgattgata atataattaa aattttgcta actatcttat tctcatcatt
     1921 cttagataac tttgatattt tgtaagtaag taaataagac agtaaattaa tagcgataat
     1981 aatactatat ttaagaatca taatcttaca aagaggacat aattcctgaa cctacacaaa
     2041 taagtgttgc tgctccccca gttatcggac cagtcgcagc agctaatagt actgctccaa
     2101 tacaaccacc gattgcagat cctaaattgc ctcttcctcc actaactatt tcgagttctt
     2161 cattatccat aacagaaaat tgttccatca tttttgtatt catgacaaat actccttttt
     2221 tcttttttta tttttgtctt gttgtaactt tgataagttt agtatatcat cgttttttaa
     2281 aatttttcat ccagatcttg aattgtcatc gaaacgtctt gaattagctt ttttatttca
     2341 agccacctct aaatgtttaa aaaaaataat ttctaatcac ttttttacca ttcaggaagt
     2401 tttaatgact attcaagatt tcataaaata tgaacttagt tttatgacat aatagaccta
     2461 tccactatat gaaaagaatt gccaatgact tcttataaac gtacatttgt tcctcaaata
     2521 gatgcgagag actgtggtgt cgctgcctta gcctcgattg ctaaattcta tggttcagat
     2581 ttttctctag ctcacttgag agaacttgca aagaccaata aagaagggac gactgctctt
     2641 ggcattgtaa aagccgctga tgaaatgggc tttgaaacaa gacctgttca agcagataaa
     2701 acgctctttg acatgagtga tgtcccctat ccatttatcg ttcacgttaa caaagaagga
     2761 aaactccaac attactatgt tgtctatcaa acaaagaaag actatctgat tattggtgat
     2821 cctgaccctt ctgtaaaaat cactaaaatg tcaaaagaac gctttttcta tgaatggact
     2881 ggagtagcta tttttctagc taccaaaccc agctatcaac cccataaaga taaaaagaat
     2941 ggtctactaa gcaagcttcc ttcctctgat tttcaaacaa aaatctctca ttgcttacat
     3001 tgttctctca agcttattgg tcactattat caatataggt ggttcttact atctccaagg
     3061 aatcttggat gaatacattc caaatcagat gaaatcaact ttaggaatca tctcagttgg
     3121 tctggttatc acctaggtta tcacctatat cctccaacaa gtcatgagct tctccagaga
     3181 ttatctccta accgttctga gccagagatt aagcattgat gtgattttat cctatattcg
     3241 ccatattttt gaacttccca tgtctttctt tgcgacacgt cgtacaggag aaatcatttc
     3301 acggttcaca gatgctaact ctattataga tgccttggct tctaccattc tttctctttt
     3361 tctggatgtt tctattctga ttcttgtagg gggagtcttg ctggcacaaa accctaatct
     3421 cttcctcctt tctcttcttt ccattcctat atacatgttc atcatctttt cttttatgaa
     3481 accttttgaa aaaatgaacc atgatgtcat gcaaagtaat tctatggtta gctctgccat
     3541 tatcgaagat atcaacggga ttgaaactat aaagtcgctc acgagtgaag aaaatcgcta
     3601 tcaaaatata gacagcgaat ttgtagatta tttggaaaaa tcctttaagc tcagtaaata
     3661 ttctatttta caaacgagtt taaagcaggg aacaaaatta gttctgaata tccttatcct
     3721 atggtttggc gctcaattag tcatgtcgag taaaatttct atcggtcagc tgattacctt
     3781 taacacactt ttttcttact ttacaactcc tatggaaaat attatcaacc tccaaaccaa
     3841 actcccatct gcgaaggtcg ctaataaccg tttgaacgaa gtctatctag tcgaatctga
     3901 atttcaagtt caagaaaacc ctgtccattc acattttttg atgggcgata ttgaatttga
     3961 tgacctttct tataagtatg gttttggacg agatacctta acagatatta atctcacgat
     4021 taaacaagga gataaggtta gcctagttgg agttagtggt tctggtaaaa caactttagc
     4081 caaaatgatt gtcaatttct ttgaacccta caaagggcat atttccatca atcatcagga
     4141 tattaaaaac attgataaaa aagtcttgcg ccgtcatatt aattacctac cccaacaagc
     4201 ctatatcttt aatggctcta tcttggaaaa tttaaccttg ggcggtaatc atatgattag
     4261 ccaagaagat attctaagag cttgtgaatt agctgaaatc cgtcaagaca ttgaaagaat
     4321 gcctatgggc tatcaaactc agctctctga tggagctggt ctatcaggag gacagaagca
     4381 acgaatagcc ctcgctcgtg ctcttttaac taaatctcct gttttaatac tagacgaagc
     4441 tactagcggt cttgatgtct tgactgagaa aaaagttata gataatctta tgtccctaac
     4501 tgataaaacc attctctttg tagcccatcg tctcagtata gccgaacgaa ctaaccgtgt
     4561 cattgttctt gaccagggga aaatcattga agttggtagt caccaagagt taatgcaggc
     4621 gcaaggcttc taccatcatc tgttcaataa ataaggagaa tgtcatgaat cctaatcttt
     4681 ttagaagcgt cgagttttat cagagacgtt accataacta tgcgacagtg ttaattatac
     4741 ctctttcatt actgtttact ttcatcttga ttttctccct tgttgccaca aaagaaatta
     4801 ctgttacttc ccaaggagaa atcgccccta caagtgtcat tgcatccatt cagtcaacca
     4861 gtgataatcc tatccttgct aatcatttag tggcaaatca agtagttgaa aaaggtgact
     4921 tactcatcaa atactctgaa acaatggatg agagtcagaa aactgcctta gaaactcaat
     4981 tacaaagact tgagaagcaa aaagaaggac ttggaatttt gaaacaaagt ttagaaaaag
     5041 cgactgatct tttttctggc gaggatgagt ttggctacca taataccttt atgaatttta
     5101 ctaaacaatc ccatgatatt gaactgggta tcacaaagac taacaccgaa gtttcaaatc
     5161 aagctaatct tgccaatagc agttcatcag ccatcgaaca agaaattaca aaagttcaac
     5221 aacaaattgg agaatatcaa gagttgagag atgctatcat aaataacaga gcacgcttac
     5281 caactggcaa tccgcaccag tcaattttaa atcgttatct tatagcctct caaggacaaa
     5341 cacaaggaac ggcagaggag ccatttttat ctcaaattaa tcaaagtatt gcaagtcttg
     5401 aatcatctat cgcaagcctc aaaattcagc aagctggtat cggaagtgta gcaacttatg
     5461 ataatagttt agcaaccaaa attgaagtac tccgcactca gtttttacaa acagcctcac
     5521 agcaacaact aaccgtggag aatcaattaa cagaattaaa agtacaacta gatcaagcga
     5581 cacagcgctt agaaaataat accttaaccg ctccaagtaa aggtatcgtt catctgaaca
     5641 gcgaatttga aggtaaaaat agaattccaa ctggtacaga aattgctcaa atattccctg
     5701 tcatcacaga tacaagagaa gtactaatca cttactacgt atcatctgac tatctcctct
     5761 tactagataa aggacaaact gtaagattaa aactggagaa gattggaaat cacggcacca
     5821 ccatcatcgg ccaacttcag agtattgatc aaactcctac cagaacagag caaggcaatc
     5881 tctttaaatt aaccgctctt gcaaaactat ctaacgagga tagtaaactc atccaatatg
     5941 gcttacaagg tcgcgtcact agtgtaacta caaagaaaac atattttgat tatttcaaag
     6001 ataaaatttt aacacattct gattaatttt cagataacac tctataacta tttattatct
     6061 tatcaaaaag gagaatcata acatggataa gaaacaaaac ctaacttcat ttcaagaact
     6121 aacaactacc gaactcaacc aaattatagg tggaggatgg tgggaagatt tcttatatag
     6181 atttaatata attgaacaaa aaaatacaaa aggatttcat cagccaatac aactataaaa
     6241 aaacaagacc aagagaacgc actctcggtc ttattttttc ttcattctat atgtattaca
     6301 gtaagtacct gacgaaaaac gtgatcttgg caggtggtat tgagactggt attgggatga
     6361 ctttccacaa ttttcataac ggtatagaga ccaactcctc tctcctcccc tttagaactt
     6421 gctccaaagg agaagatttc agaaatatcg attccctctt ctttgatgga attttcaatg
     6481 ataaaggtct cctgtgctcc attttttaaa aaggcaattg aaacatgagg ttgacaggct
     6541 tctacactag cttcaatagc gttgtcacaa aggatagaca caacggttag aaaatcaagt
     6601 agactcatcc cctctacctg aatctcctct ggaacttcga cattaaagac aatgttctta
     6661 tctctagctt ttagaaattt ccctgctagg agacttttga gggctttatc acgaatattc
     6721 accaatcgac caaggtcata tttattgtcc tgcaattttt cactagaatc ctttaagacc
     6781 gagtcgtaga tctcttttat ctgctccata tcctcctctt caatgcccag acgtaagcta
     6841 gtcaagaggt tggtgtagtc atggcgaaaa ctccgtactt ccttataaag ctcctctata
     6901 tgccgactat accgctccat ctctctgtag cgcaagtcct gctcttggtt cagtctctca
     6961 tggagtttgt ccttcaaata ggtatccaat ttcttgataa tccccataaa aaagagcagg
     7021 taaaagacta ggatgagatg gcgaacagtc gttgattgaa tcccctgttc atattcaaag
     7081 taagacagat tttgtatcac caaatagtaa gcccccatta tccagttaat ctgagtcagg
     7141 gacttttgaa aatctttatc gagaatcccc tttctcaagc tagtgaaatc atagtccaac
     7201 catttcaaaa aagctagaga aatgaagaaa ttgaaaatta ttatacataa ccaaataaat
     7261 gagtagtcat catatacttg cccttgtccc aaaaatggaa gcacaaaata ggaaacacct
     7321 ctataaaaga gattcactaa tatcattgga aagagaccat aaaagagaag gagtttttta
     7381 ggaagttctc ttaacaataa gaaagataag cctatgccgt acaagggttc cataaaataa
     7441 gatagataag tatttcctac catatagcca agcattccaa aaacaacggc caacagtatc
     7501 ttaaaaagaa aggccttaaa aatcctctca aaagtgagac taattccatc taccttaaag
     7561 aatatgacaa tttttaatcc gtgagtaaca agtgtataca acaatatcca agcaacattc
     7621 ataaactctc ctagctcagt gtaagttatt aatagcctca gacacttccc tgaccttata
     7681 acgcgcgatt agacaacttc caccattggg aaagaaaagc agtttttctt tcttatctaa
     7741 atgcaccaca ttggcaggat tgatgagaaa agagcgatgg cactgcaaga gacgaggctc
     7801 ctgcttgaga acctcctcta gactcgctgt aaattccagc ctgtctgtct tggtatagag
     7861 aataacacga tggggtcttg tggacgtttc gagatagtaa acctctttaa aaggatactg
     7921 gaattgagca aattttgatt taaagtaaaa gcaatcttcc gctagacttt tactgtcttg
     7981 accattggca tagaggaggg ctgtctcgat acgagattca aactcctctg ccgaaagggc
     8041 cttatcaata tagtccagag cagacacttg gtagcgaaag gacaggggca taaactccga
     8101 gtgagtcgtc acaaagacaa tcagggcata cggatcccga tcccgaatct ttctagccac
     8161 ttccagaccc ttcatctcct catttcgaat ctcaatatcc aaaaagaata gctgatgggc
     8221 ccccttctca tgcacctctg ccagcagttg gtctggcttg ccaaatacct caaaagagct
     8281 gggagtgata tgatgttcct tcaagagttt ctcaatcgtc gtttcaatcc tagtctgttg
     8341 ggaaaaatca tcctctaaaa caaatattct catcttctta ctctccctct ttcaaccatt
     8401 tttgacgaat ttctctatag cgacgtctgg catacttgac agcgtattga ccttcttctc
     8461 cgagaaaaag gattctttct tgaaaatcaa tcgattttaa tttatcaaga ttaaccaaac
     8521 aatttcgatg acatctcatc aaggtttccc catattggtt ctcaagatta cttaaatttt
     8581 gaagcatatt aaaactagct tcttctgtaa caatctgtac ggtatgggct ttagttggat
     8641 gtgtttggat atagtagata tcgtcgacgt ttactttata gactgttttc tgcgtctgaa
     8701 taatcatatg tttcattgga ttctcctcct aagaaaagaa taacagaaaa gttctagccc
     8761 aagcccaccc aatcctaaac agtctttgaa agctcctaaa aggattattt ttctacaaca
     8821 tcatgatgag cttacaacta ttttatcata aaattcactc agcgcaattc aagacatttc
     8881 aatgacaatt aaagatttga ataaaaaaaa agaattaaaa atgataaact aacagtatca
     8941 aaacacagtt gccagaagta agactggcac ccagattaaa ggaggcattc ccatgacaga
     9001 tacagacccc atcaaaagag ctcatacttt gattactgac ttaaacaaag cctaccaagc
     9061 atgcaaacag gcaagcgctg acgacgtccg ctttcaggag caattaaact ctattcttgg
     9121 ttttttagcc aaggctgaaa cagtggataa tcgattcttg attgaactag aaaaatttta
     9181 ccagacttcc agtcttctca tgggactcag cgctcttgat ccagatgctc caactcgcgc
     9241 cgcttggcgg gcctatgacc gcttccactt tgaccaagtc aagaccaagt taatactcaa
     9301 tgaaaatcaa agagcaaact aggaagctag ccgcaagctg tacttgagta cggtaaggcg
     9361 acgctgacgt ggtttgaaga gattttcgaa gagtataagt ctctacggac caaccattat
     9421 cctgtagtaa caaaaaagaa gctgagacag actgaactca acttcttttt tagtgtcgta
     9481 tcagcaatgt tagtcctgca tctgacgttt tacctgataa ggcaaataca agactagtaa
     9541 aaccaaacca gctcctagta aggctagaag ggccagtttt tcttggaagg taatcaaccc
     9601 aacaactaat tccacaagta aaacaaaact ggtcaatcct cgaactacct cctgtaagcc
     9661 tttttccttt tgccccttgt ccagcggaaa gagttgggtc aaatactggt agtcaaaggc
     9721 atgatagagg gccagcaact ggaagagcaa gaggtagtta aagagaacta ccactgctgt
     9781 cgcaatccaa gcttgctcga taaaaacctg cgccagtacg gaaagtaata gaagacgaag
     9841 actgagagca aagaggtcgc catttcgcag ataagaacgc agatagagat tttgccaaat
     9901 cttcccaggc accttctgaa cagcctttaa gataaagtcc agataggcac gacgcttaac
     9961 gctgtttgaa attcccttga cctgcgtaaa gagggcaaag aaacgaagca agacttgctt
    10021 acgcttgctt tcttgagaaa taacatagtc ccagtccagt ccagtttcag taaaaaattt
    10081 gctggccttt tgacgaaagt ggaaatattt tcctaccccc aataaaagca catatagcag
    10141 aaaaactggc aagccataac ccattgctaa aaataaaggc gcaaataaca gcaagaaaag
    10201 ggtctgtaca aagagccaaa agactaggga aatgccagtt tgacgcttga gatggagctt
    10261 gattgcctct tctccaacta agagaaagag cttgtctgga gcctccatat aggtggcaat
    10321 tcctccccaa agtaagagta aaacagacgt aattcctaca aacaaaagga taggccaatg
    10381 attttcagga aaatgttgta agagttgact gtactggtag gctagaaagc ccaacaggac
    10441 aagcaggaac aagacaaagt ggtcattgag cacatagcgc agataacaaa gacactcctt
    10501 acgaaaggcc tgctttctct ttaaaaacaa gtctttcata gatcctcctc tttggtcaga
    10561 gccaagtaaa tatcattcaa actagcctca ggcatatcaa aggcttcacg tagttgcagg
    10621 agattgcctt tggcacgcac ctctcccttg tgaagaatga caaaggcatc acacatcttt
    10681 tccgccgaat ccagcacgtg ggtactcatg agaatagact tgcccttttg cttctccact
    10741 tccaaaagct gaatcaaatc agaaatagcc agcggatcaa gaccaaggaa aggctcatcc
    10801 acgatgaaaa gacttggatc caccacaaaa gcacagataa tcatgacctt ctgcttcatc
    10861 ccttttgaaa aatgaacagg gaaccagtct aatttctgtt ccaaacggaa catttttaac
    10921 aagggctcta ctcgttcgaa agccactttt tgctcaatac cgtaagccat agcaaccgtt
    10981 tcgatatgct ctctgagggt caattcctca tacagactag gcgtctcagg aatgtagcca
    11041 atctgcttgc ggtagctagt cgcatctcct tgcagagtca ggccattgat attgatggag
    11101 ccactataag gtgccaacag accgataatc tcattgatcg tcgttgattt cccagcacca
    11161 ttgagaccaa tcaaaccgac caactgccca ctttcaacag taaaggacac atctttcaaa
    11221 acaggaacat gaacatagcc acctgtcagg tttttaattt ctaacatatt ttctccaaat
    11281 ctggtataat gtagctatat tatatcaaaa ttcagtacag tagaggtaga ttttatgtca
    11341 gattgcattt tttgtaaaat catcgcaggg gaaattcctg cttcaaaagt atatgaagat
    11401 gagcaggtcc ttgcctttct tgatatctct caagtaacac taggacacac cttggtcgtg
    11461 ccaaaagaac actatcgcaa tcttttggag atgaatgcta cgagcgccag ccaactcttt
    11521 gcccaagtac caaaagtagc tcaaaaagtc atgaaagtca ctaaggctgc tggtatgaat
    11581 atcatttcca actgtgaaga agtcgctggt caaacagttt ttcatactca cgttcacctt
    11641 gtgcctcgct acagtgctga cgatgacctc aagattgatt ttatcgccca cgaaccagac
    11701 tttgacaaac ttgctcaagt cgctgaaacc atcaaaaacg cttaaggagt tgctatgaaa
    11761 ttatccaacc tactgctatt tgcaggagct gcagccggaa gttatctggt tacaaaaaat
    11821 cgccaaacca tcacagatga agtcttgaat accactgacc gcgttcaagc tatcaaagac
    11881 gatgtggata ttatccaaaa tagcctgcaa atcatcgacc agcaaaaaga acttatcaag
    11941 gaataccaag aagacttgac ttacaagttt aaggtcttgg aaaaggatat ccagactaga
    12001 ctagctgtga taaaagaaat gcagggaact gaagataagt aaaaagagcc ccccggctct
    12061 tttttaaaac gtaaacaagt tatagtgaat tgaatttaga atagcacatc atagtttcta
    12121 aagcattgtt agagattact ttaaaatcct cttatcaatt tgttcatatt ctatttcaat
    12181 ctactatata tatcccatca actatgcatc ataatttagg taactcatac tcaataaaaa
    12241 tcaaaaagca aactagaaag ctaggcacag actgctcaaa acaccgtttt aaggttgtgg
    12301 atagaactga cgaagtcagc tcaaaacact gttttgaggt tgtggataga actgacgaag
    12361 tcagtaacca tacccatgac aagccgacgc tgacgtggtt tgaagaaatt tttgaagagt
    12421 atcattcacc atttcacaac taaatcgaag actttctgcc gtaatgaaaa cacctgaaac
    12481 agcttggttt cagctgtccg gaaactttaa gacttaggtt caaagtttag gtatggaact
    12541 tcgaaggagg tcgctaccgt ccgtcattac ttaggaaagt cttaaaaaat ctataaagta
    12601 aaaagagccc gacagctctt tttgtttata ctcaatgaaa atcaaaaagc aaactaggaa
    12661 actagccacg ggctgctcaa aacactgttt tgaggttgta gatacgactc acatatatac
    12721 ggcaagccga cgctgacgtg gtttgaagag attttcgacg ctgacgtggt ttgaagagat
    12781 tttcaaagag tattattctc catcaaaggc atctttaata tggtcaaaga agcctttttt
    12841 ctttggattt actttcaagt caccagcagc cgcgaattct ttcaaggcta ctttttggcg
    12901 gtcgttcaag cctgtcggtg ttacgacatt aacagtaacg tattggtcac caactgcacc
    12961 gccacgaagg ctcggtgccc ccttactacg taggcggaat ttcttaccag tctgagttcc
    13021 ctctggaata accaattcaa catcaccgtg aacagttgga atatctactg tatcaccaag
    13081 agccgcttgg acaaagttga ggttgagatt gtagaagata gtcgttcctt cacgttcaaa
    13141 cttgtcgcta gcttctacag aaactactac atacaagtcc ccataaggtc caccgttaaa
    13201 gcctgcttcg ccttgaccag cgaggcgaat ttgttgacct gtttccacac cagcagggat
    13261 tttcacatgt acgctatgag cttgtttctc atgacctgtt ccatgacagg ttgtacatgg
    13321 atatttgatt tcttttcctc gaccgtgaca gacatcacag gttacttggc gacgcatcat
    13381 accaagagga gtctgcgtat cgacgttaat gacaccagcg ccatgacagc gtccacaagt
    13441 gactggactt gtccctggct tagcaccaga gccattacat gtacgacagc cagcttcacg
    13501 atgatactta acttccttct cagttccgaa gatagcttct tcaaaggtca aattgacacg
    13561 atactggaga tcatctcctt ggcgaggagc gtttggattg cgcgaagaac cgcctccgcc
    13621 gaagaaactt gaaaaaatat cctcaaaacc accgaagcca cctgccccat tgaaaccacc
    13681 gaaaccacca gctccaccaa aaccaccatt ggcgcctgca gcaccatact ggtcataggc
    13741 agcacgtttt tggtcgtcac tcaaagtctc ataggcttct tgaacttcct tgtacttgtc
    13801 ctcagcacca ggctccttgt tgatatctgg gtgatatttt ttggaaagct tacgataagc
    13861 ctttttgatc tcgtctgccg aagcgttttt tgacaccccc agacgatcat aaaattcagt
    13921 attgttcata caagatacca agaccgtaaa attcgactga aaaataggaa atctgacgct
    13981 ggagcgacgc tcctagacag atttctcttt tttccgagaa tttaggtcgg gttcaattcc
    14041 tttcttttat attgatgaga taatactcca gccactcggc cctatccctt tttaccgaaa
    14101 aacagaggct gagttgcaac ctctgtggtt agattattca tttgaaataa aaatggttgt
    14161 attatctcta gtagtaatct tcaaagacct tttagctaaa tcaaactcaa atttattata
    14221 gtgtgggtct tgtgttttat ataggtgtaa ctcctgacat atatgatccg aaaagtaaat
    14281 cataacatct ttaaacacag aagtgtggtc atatttactc ttaccaacag ctacttctgt
    14341 aaattcttta taaatgacat ttccatttct ttccacagtc accagcattt ctgttggatt
    14401 ataatccaaa ttaaataatt cttcaaaaaa ctttatcttt tcatgataat ctgcaatgtc
    14461 agaaagatta tttttattaa cactcataac actagcccct tatttttcag taaactctcc
    14521 gtctacgacg tcatcgcctg cgtttcctgt tgcttgtgcg ccttctgctc cttcttgagc
    14581 ttgttgcgct gctgcagctt gttcgtagag tttaacagca agtccttgag ctttttcgtt
    14641 caatgcttca agttttgctt tcatgtcgtc caagttgttg tcttcttgag ctttcttaag
    14701 gtcatcaagg gcagcttggg cagcgtcacg ttctgcgtcg aagcctttac cttcagtttc
    14761 cttgattgtc ttttcagtcg caaagattgc ttggtctact tcattacgaa ggtctacttc
    14821 ttctttacgt ttcttatcgg cttcagcgtt tgcttctgca tctttcatca tgcggtcgat
    14881 ttcttcgtca gtcaaacctg agttcgattg gatgacaata gtttgttctt tttgagttcc
    14941 aaggtctttg gccttaacag acacgatacc gttcttgtcg atgtcaaatg ttacttcgat
    15001 ttgaggaatt ccacgaggtg cagctgggat atcagtcaat tggaagcgtc caagagtctt
    15061 gttatctgct gccattgggc gttcaccttg aagaacgtgg atatcaacgg ctggttggtt
    15121 gtctgctgct gttgagaaga cttgtgattt agatgttggg attgtagtgt tgcgatcgat
    15181 aagttttgta aatactccac ccattgtttc gataccaagt gacaatggcg ttacatcaag
    15241 aaggacaacg tccttgacat caccagtaat cacaccacct tggatagccg cacccatagc
    15301 aactacttca tcagggttta ctgatttgtt tggttcttta ccagtttcag ctttaacagc
    15361 ttcaacaacg gcagggatac gagttgaacc accaacaagg ataacttcgt cgatttctga
    15421 caagctcaaa cctgcatctg aaagggcttg acgaactgga acttttgtac gttcaacaag
    15481 gtcacgagtc aaatcgtcaa atttcgcacg agtcaaagtc atttccaagt gaagaggtcc
    15541 agcctcacct gcagtgataa atggcaagct gatttgtgtt gaagttacac cagaaaggtc
    15601 tttcttcgct ttttcagccg catctttcaa acgttgcatt gccatcttgt cagtagacaa
    15661 gtcgataccg ttttctttct tgaattctgc taccaagtgg tcaatgattt tttggtcaaa
    15721 gtcgtcacca ccaagtttgt tgtcccctgc agttgacaat acgtcgaaga caccgtcacc
    15781 caattcaagg atagagacgt cgaatgtacc accaccaagg tcaaatacca agattttttc
    15841 ttctttgtca gtcttgtcca aaccataagc aagagctgct gcagttggtt cgttaacaat
    15901 acgttctact tcaagaccag caattttacc agcgtctttt gttgcttgac gttgagcgtc
    15961 gttgaagtaa gccggaactg tgataacagc tttggttact ttctcaccaa ggtagtcttc
    16021 agcgtagcct ttcaagtatt gaaggatcat agctgagatt tcttgtggag tgtattcttt
    16081 tccatttgca gaaacttttt cagaagttcc catcttagat ttgatagaga taactgtatc
    16141 tgggtttgta actgcttgac gttttgcagc atcaccaacg atgatttctc cgtttttgaa
    16201 tgagactaca gatggagttg tgcggtttcc ttctgggttt gcgatgattt tgctttcagt
    16261 tccttcaaga actgcaactg ctgagtttgt tgtacctaag tcaataccga taattttaga
    16321 catgtgtttt tctccttgtt agttaatttt ctatttttct ttttgatact cttcttaagt
    16381 ggcgacgccg tcagagcttg acttcgtcaa tctctttgac taaactttga gcctaaggtc
    16441 tcaaaatttg cgcaaatagc accacggcga agagtatcgt ctttggttcg cttcgctcac
    16501 tattacaaag ccaaacatat tttatctttc ttcatagttt attgtcgttt cggacaagtt
    16561 ttctattatg taaattgcga cacgaggagt cgaaatcgat tttatttcga cgacgagtta
    16621 gtaaggaagc taggcaaacg tcatagcgat tgccgttttc tgacgagttg ctttagctac
    16681 cgtcagaatt gccgaatcga acacgcccta agctctgagt aaaaaagata gattttcttg
    16741 tgttcatcga acacttcgtc aatctcctat ttttactgcg agctttttac gagctttgta
    16801 tcttagttat acaccactac cattgctggg cgtaggatgc ggtcatggag tttgtagcct
    16861 ttttgaaaga cttgggcgat ggtatctact gggtgttcat cgtctgctgg gagagtttgg
    16921 atggccatat ggtagttatg gtcaaattcg ccatctgctg cgatttcttc aattccttct
    16981 tctttcaaag cgtgaatcaa gctttcttgc accatcccca agcccttctt cacatcatct
    17041 gtcaaacctt caactgcaag tgcacgctca aggttgtcaa gagatggtaa gattgctttt
    17101 gccaagtcct ggctacgata acgttgcaag ttttgacgtt cttcattggc acggcgttgg
    17161 atattttgca tttctgcatg agcgcgaaga tatttgtttt cgaactcatc tgcacgttca
    17221 tttgccaagt ccaactcaga cttttcagga gttgtttctt cagctgtttc cacaacttcc
    17281 tcttcttgaa cttcttctac ttcttcattt tttatatctt gggccatgtt cgcctccttt
    17341 aatgatttca atcttaatgt acttcgtaat gattactgct gaggtagcgg taaaaatctg
    17401 tcaacttcat ggtcaaaaca cggttgacca cattgacttg attgattagc tgttggtaat
    17461 ccagattaac tggaccgata atggctagaa ttccaactcc ccgataagga atgaggaact
    17521 tactactaat caccgctagg tcagctaaac aggactcttg accgtctgca acacgaacat
    17581 tttgcatctg atcctcacgc aacccctcac gaatctccaa ggccaccttt tgcggttggt
    17641 caaagaactg ataggcttct agattggcaa aattcaagag attgaccttg cccgccatca
    17701 caatgttttc gttgaacatt tccttaaaga tgtgttcaaa gagatcgatg acattatccg
    17761 ttgttgtaaa gtaacgctgg ataatctgcg gaatctccgt ccgaatcttg tagtgaatat
    17821 ctaaaacggt gtgaccgagg aaacgttcct gaatgatgct cttcagtttc agcaaatcct
    17881 cctgcaagaa gttccttgga atcagaaact gactagtaac cgttcgcgac tcgtctaggg
    17941 taaataccgc caaggctgta tgttgcccca aaacaacgat atcaaaggct gtcaaacgtt
    18001 gcctgctcgg ctcaacatcc agtgccacta ccgtacagcc actcaggcct gttagcaagt
    18061 tagcagcctc ttgcagaata tcctccaatt tgaagaattc ctgatcaaag gctttgacaa
    18121 tctcatatac ctcattttca gccagccggt gaaaatccag tgagtgtttc acatagtact
    18181 gaaaaccagc aacacttggc atccgaccgc ttgaagtatg agccttctca agcaaccctt
    18241 gtttttctag ttccgccatg tcattacgaa tggttgcact gctagagtta atagactctt
    18301 gcaaggcttt tgatccgaca ggttcgtgcg ttttggtaaa gatgtcaata atcagattta
    18361 aaatatcctg ctgacgctct gtaaccatct catcactcct ctctgtctga tcaattagca
    18421 ctcaatgcat ccaagtgcta acttatgatt ctattataca cccttaaaag agaatgtcaa
    18481 gacaaaaact caaaaaatta gcactctttt atcaagagtg ctaaaaatca atctgaagac
    18541 ctagaacctt gctattcatc tactcggtat ttccttttta gtctgaaata accatgaatt
    18601 agataagaaa tcagaaaagc atataaaaca aaaataagaa agaaagacat agaaagatcc
    18661 tctctaaaca aactcgtaca aacaacaaga ccacctaaga aagtagttgt acaggaacga
    18721 agtctagatc gcataacttc ccatttgagc cccttactca tatagacttg atcctctgga
    18781 agtaaatcag aagacgattt acgaagaatc gaacaagaac ctgctcctat caattcccaa
    18841 cctctatctc taaaatcttg cagttcatgc ttatattttt taagaaatct agaatcatag
    18901 atacggtaga tgacatcgtc tggttgacat tggtcaaaat agaacaaacc aaaacgactc
    18961 gttctatacc tccaaccttt caaatgcatc tcatgtaaat attcttcttc cttgtccaaa
    19021 tcaacaatgg tgaaaatccg aaattctact ctgctattca ttgtcttacc ccaaaattag
    19081 aaaacatgcc tggcgttatt tattagataa ttctttccac ttttgactca atctccaaaa
    19141 aatataagaa atctgaatcg caaaaactat caataaaacc caatctatta tgaaaatcaa
    19201 aaacactttc caactgaaag aactacctcc agtgacaaac tttgagcaaa acggtagtag
    19261 agctaaaaag agaagtaaaa taggaagcat ccgcattgtt aaaatccgtt tggcataaaa
    19321 aaatctttat ttaaactaaa atattatagc aaaatttacg ccagtttttg aacggctgat
    19381 gtagatattt tatactttca aaatgtttaa atgtgattat ttatttttga aaaatagctc
    19441 accagcccga ctgaaagtgc ttatagaatg ataataagtc gcctgccgaa aacagcggaa
    19501 aatagcggtg ttatgcggag ataatctgac gcgatgcgaa agtatattgc atacttattt
    19561 tcaacaattt agcagagtat ttttataagt gtgatataat agaagtataa tttgttctga
    19621 tagtttattt tatggagaag tagattttta gaatgcggag ggttcaatat ggttgagttt
    19681 ataaagtcta agaaagaaat gagtgaggag gatattaaag caaatttcat cactcctgct
    19741 attgtatcca aaggatggaa aaatggtgag catatcgctt acgaagaata cttcactgat
    19801 ggtcgaattg aggttagagg agataaggct cgtcgtaaag aaggaaaaaa atcagactat
    19861 tcactgtatt accaatttgg aactcgaatt gcaattgttg aggcaaagga taataaacac
    19921 agcgttcgag caggattaca acaagctatt gaatatggag agattttaga tgttccattt
    19981 gtttattctt cgaatggtga tggctttatt gaacacgacc gtatcacgag agaagaacgt
    20041 gagctggagt tagacgaatt ccctactcgt gaagaattat tttctcgtat gacgaaggaa
    20101 aaaggattga cgtacgaaat tacagaagct atctcaactc catactatac agacgccttc
    20161 tcaatgaaaa cgccacgcta ttatcagcaa atagctatca accgtactat tgaaacagtt
    20221 gccagaggac aaaaacgagt aatgtttgtg atggcaacag gaacagggaa aacgttcatg
    20281 gcttttcaaa ttattcatcg ccttcgaaaa gctggtttgg ctaaacgagt tttattctta
    20341 gcagatagaa acatcttagt agaccaaacg atggctgaag actttaagcc attcgaaaag
    20401 gtaatgacga aaattacacc aaaacttttg actgctcctg aaaaattaaa ttctttcgaa
    20461 atttatctag ggctttatca gcaactaact ggtgaagatg gaactgaaac acattatcaa
    20521 aaatttgaca aagacttctt tgatttaatc gtaattgatg aagcgcaccg tggttcagct
    20581 aaggaaaaca gtaactggcg taaggtaatt gattatttca gttctgcgac acagattggg
    20641 atgaccgcta ctcctaaaga aaccaagaat gcttccaata cggaatactt tggtaagcca
    20701 atctatactt atagtttaaa acagggaatc gaggatggtt ttttggctcc atatcgtgtt
    20761 atgagggtta atttagatgt ggatgtggat ggttatcgtc cagaaactgg aaaagttgat
    20821 gctaacggac aattaataga agataggtac tacggcagga aagattttga taaaaccatt
    20881 gtcattgatg atagaacgca aagagttgcc aagtttgttt ctgattatat gaagcaaaac
    20941 aatgcacgat ttgataaaac aattgttttt tgtgttgata ttgaccatgc cgagcgaatg
    21001 cgtgctgcac ttgtaaaaga gaatctagac ttagtccaag aagactatcg ttatgtcatg
    21061 caagtaactg gtgacaacgc tgaaggaaaa gctcaactgg ataactttat ggatgtcaat
    21121 tctaattttc ccgctattgt aacaacgtct aaattattaa cgacaggagt taatgctaaa
    21181 acatgtcgtt tgattgtttt agactctaat atccaatcca tgactgaatt taaacaaatt
    21241 attggtcgtg gcacacgtct ttatcctcaa aaggggaaag aattttttac gattattgat
    21301 tttcgaaatg ttaccaattt gtttgctgac cctgattttg atggtgagcc agtgaaggtg
    21361 ctggaaacag gtgcgaaaac agtcagtggt tctacgcctg gtttcgtagg tgaggaaggt
    21421 gacccagtag aaaaatatat cgttacagac aagcaggtta ccattcttaa ttctactgtt
    21481 caagtattgg atgaaaacgg gaaactgatt accgaaagcc tgaccgacta cactcgaaag
    21541 aatatcttag gtagctacgc cactttgaac gattttatca cagtttggca tacggcagat
    21601 aagaaacatt atgggaagtt tgctgatgga agcactcaag aaattgatgt tccttatgat
    21661 attcctgata cttgggagtg ggtgaggttt tctacattgg ttgaaattgt cagaggtggc
    21721 tctccacgac caatcaaaga ttatcttact tctgaagtag atggaataaa ttggataaaa
    21781 ataggtgata ctgaaaaggg tgaaaagtat ataaataatg ttaaagaaaa aatcaaaaaa
    21841 tcagggctta acaaaactag atttgtaaaa aaaggtacat ttttgttaac taattctatg
    21901 agttttggta gaccttatat tttgaatgtt gatggtgcaa tacacgatgg atggttggct
    21961 atttcgaact atgaaaactc attaaataaa gattacctat tctatattct ttcatcaaat
    22021 gtagtttatt ctcaatttct atctctaatt agtggagctg ttgtgaaaaa cttgaatagt
    22081 gataaagttg cttctattct tatc
//
LOCUS       DAVBEO010000036        22017 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 009
            SAMEA1678075-rid20185393.denovo.036, whole genome shotgun sequence.
ACCESSION   DAVBEO010000036 DAVBEO010000000
VERSION     DAVBEO010000036.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678075
            Sequence Read Archive: ERR226392
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 22017)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22017)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980207.1
            Genome Coverage       :: 150x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:50:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 72 of 147
            Pseudo Genes (incomplete)         :: 72 of 147
            Pseudo Genes (internal stop)      :: 42 of 147
            Pseudo Genes (multiple problems)  :: 32 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22017
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678075-rid20185393.denovo.036"
                     /strain="KS 009"
                     /db_xref="taxon:1313"
     gene            51..233
                     /locus_tag="VQ543_001412"
     CDS             51..233
                     /locus_tag="VQ543_001412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000842022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase"
                     /protein_id="HET2612125.1"
                     /translation="MKSQKIKVSFTQSKIVTPILLVNKTIVWYGAMPLLGKVDEMTIL
                     RLESASIVSELVAGLR"
     gene            533..1372
                     /locus_tag="VQ543_001413"
     CDS             533..1372
                     /locus_tag="VQ543_001413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HET2612126.1"
                     /translation="MIIKRILNHNAVIAQSKKDIDILLFGRGIAFGRKTGDKVNPIDI
                     EKSFFLKNRDNMTRFTEMFINVPLELVYITEKIINLGKITLGNNFDEIIYINLTDHIS
                     SSIERYKEGIIISNPLRWEISKYYKEEFELGKRALQIIKKELGIELPIDEAAFIALHF
                     VNANLENNFQESYKITEIIMGIEKIIQDFYCTEFNQDSIDYYRFITHIKLFAHRLVEN
                     TTYCDDDDEDLLALMKNKYPREYECGEQVAMFIQTEYNYLLTSSELVYLMAHIRRLTK
                     NLD"
     gene            1390..3228
                     /locus_tag="VQ543_001414"
     CDS             1390..3228
                     /locus_tag="VQ543_001414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HET2612127.1"
                     /translation="MSYKDTVQKILDVIGGEKNVNRVTHCVTRLRLELKDENLVNDDD
                     VKKIPDVIGIMKKNGQYQIILGNDVANYYKEFVKLGNFESDSVVQGHKGNILERIIEY
                     IAGSMTPIIPAMLGGGMLKVLVIILPMLGILQSDSQTIAFLTFFGDAPYYFLPLLLAY
                     SASQKLKVTSTLAMSVAGVLLHPNFVQMVQSGNPLSLFGAPVTPASYGSSVVPILIMV
                     WLMKYIEKIIAKLTPAITKSFLQPTLVLLVSSCIALVVVGPIGVIVGEGLSNLVGQMY
                     GVAGWLTLAILGAIMPFIVMTGMHWAFAPIFLAASIATPDVLILPAMLGSNLAQGAAS
                     MAVALKSKNNNTKQIAFAAGFSALLAGITEPALYGVTLKYKKPLYAAMIGGGLAGLFA
                     GLTSVKAYLFAVPSLIALPQFIYSDVPSNIVNALIVAVISVVITFVLAYIFGIDEEES
                     SSNLEVKAGVSNKKMIFSPISGEIIPLSDVQDKTFSDKLIGDGVAIIPSEGKVYAPFD
                     GKITNIFPTKHAIGLKSDEGVELLIHIGLDTVELKGQGFISHVEEGDRVFKNQLIFEM
                     NLNLIKTKGYETVTPVIVTNTNDFLDVLVLPNNQTIEHSKELLVIL"
     gene            3241..4656
                     /locus_tag="VQ543_001415"
     CDS             3241..4656
                     /locus_tag="VQ543_001415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HET2612128.1"
                     /translation="MTIFPDDFLWGGAVAANQVEGAYNEDGKGLSVQDVLPKGGLGEA
                     TENPTEDNLKLIGIDFYHKYKEDISLFSEMGFNVFRTSIAWSRIFPKGDEEEPNEAGL
                     KYYDELFDELHAHGIEPLVTLSHYETPLYLARKYHGWIDRRMIHFYEKFARTVLERYK
                     DKVKYWLTFNEVNSVLELPFTSGGIDIPKENLSKQELYQAIHHELVASSLVTKIAREI
                     NSEFKVGCMVLAMPAYPMTPNPKDVWATHEYENLNYLFSDVHVRGYYPNYAKRYFKEN
                     DINIEFAAEDAELLKNYTVDFLSFSYYMSVTQSAIPTQYNSGEGNIIGGLVNPYLESS
                     EWGWQIDPIGLRIILNRYYDRYQIPLFIVENGLGAKDQLIKDELNNLTVQDDYRIQYM
                     KEHLLQVAEALQDGVEIMGYTSWGCIDCVSMSTAQLSKRYGLIYVDRNDDGNGTFNRY
                     KKMSFTWYKGVIESNGESLFK"
     gene            5248..6294
                     /gene="pheS"
                     /locus_tag="VQ543_001416"
     CDS             5248..6294
                     /gene="pheS"
                     /locus_tag="VQ543_001416"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013903845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit alpha"
                     /protein_id="HET2612129.1"
                     /translation="MSTIEEQLKALREETLASLKQITAGNEKEMQDLRVSVLGKKGSL
                     TEILKGMKDVSAEMRPIIGKHVNEARDVLTAAFEETAKLLEEKKVAAQLASESIDVTL
                     PGRPVATGHRHVLTQTSEEIEDIFIGMGYQVVDGFEVEQDYYNFERMNLPKDHPARDM
                     QDTFYITEEILLRTHTSPVQARAMDAHDFSKGPLKMISPGRVFRRDTDDATHSHQFHQ
                     IEGLVVGKNISMADLQGTLQLIVQKMFGEERQIRLRPSYFPFTEPSVEVDVSCFKCGG
                     EGCNVCKKTGWIEIMGAGMVHPRVLEMSGIDATVYSGFAFGLGQERVAMLRYGINDIR
                     GFYQGDVRFSEQFK"
     gene            6294..6803
                     /locus_tag="VQ543_001417"
     CDS             6294..6803
                     /locus_tag="VQ543_001417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET2612130.1"
                     /translation="MIRKVEMADVEVLAKIAKQAFRETFAYDNTEEQLQEYFEEAYSL
                     KTLSTELGNPDSETYFIMHEEEIAGFLKVNWGSAQTERELEDAFEIQRLYVLQKFQGF
                     GLGKQLFEFALELATKNSFSWAWLGVWEHNTKAQAFYNRYGFEKFSQHHFMVGQKVDT
                     DWLLRKKLR"
     gene            6880..9285
                     /locus_tag="VQ543_001418"
     CDS             6880..9285
                     /locus_tag="VQ543_001418"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit beta"
                     /protein_id="HET2612131.1"
                     /translation="MLVSYKWLKELVGIDVPSQELAEKMSTTGIEVEGVESPAAGLSK
                     IVVGEILSCEDVPETHLHVCQVNVGEEEERQIVCGAPNVRAGIKVMVALPGARIADNY
                     KIKKGKIRGLESLGMICSLGELGISDSVVPKKFADGIQILPENAVPGEEVFSYLDLDD
                     EIIELSITPNRADALSMRGVAHEVAAIYDKAVNFKEFTLTETNEAATDALSVGIETDK
                     APYYAARILDNVTIAPSPQWLQNLLMNEGIRPINNVVDVTNYILLYFGQPMHAFDLDT
                     FEGTDIRVREARAGEKLVTLDGEERDLDVNDLVITVADKPVALAGVMGGQATEISEKS
                     SHVVLEAAVFNGKSIRKTSGRLNLRSESSSRFEKGINVATVNEALDAAASLIAELAGA
                     TVRKGIVSAGELDTSDVEVSSTLADVNRVLGTELSYADVEDVFRRLGFGLSGNADSFT
                     VSVPRRRWDITIEADLFEEIARIYGYDRLPTSLPKDDGTAGELTVTQKLRRQVRTIAE
                     GAGLTEIITYVLTTPEKAVEFTAQPSNLTELMWPMTVDRSVLRQNMISGILDTVAYNV
                     ARKNKNLALYEIGKVFEQTGNPKEELPNEINSFAFALTGLVAEKDFQTAAVPVDFFYA
                     KGILEALFTRLGLEVTYTATAEIASLHPGRTAVISLGDQVLGFLGQVHPVTAKAYDIP
                     ETYVAELNLSVIEAALQPAAPFVEITKFPAVSRDVALLLKAAVTHQEVIDAIQAAGVK
                     RLTDIKLFDVFSGEKLGLGMKSMAYSLTFQNPEDSLTDEEVARYMEKIQASLEKKVNA
                     EVR"
     gene            complement(9458..10459)
                     /locus_tag="VQ543_001419"
     CDS             complement(9458..10459)
                     /locus_tag="VQ543_001419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000597989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HET2612132.1"
                     /translation="MIKTFLSALSVILFVIPIITYSFFPSSNLNIWLSTRPILAQIYA
                     FPLATATMAAILSFVFFSLSFYKKNKQIRFYSGILLLLSLILLLFGTDKTLSSASNKT
                     KTLKLVTWNVANQIEAQHIERIFSHFDADMAIFPELATNIRGEQENQRIKLLFHQVGL
                     SMANYDIFTSPPTNSGIAPVTVIVKKSYGFYTEAKTFHTTRFGTIVLHSRKQNIPDII
                     ALHTAPPLPGLMEIWKQDLNIIHNQLASKYPKAIIADDFNATMRHGALAKISSHRDAL
                     NVLPPFERGTWNSQSPKLFNATIDHILLPKNHYYVKDLDIVSFQNSDHRCIFTEITF"
     gene            10615..11103
                     /locus_tag="VQ543_001420"
                     /pseudo
     CDS             10615..11103
                     /locus_tag="VQ543_001420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155321.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            11187..11453
                     /locus_tag="VQ543_001421"
     CDS             11187..11453
                     /locus_tag="VQ543_001421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET2612133.1"
                     /translation="MEGCPSELFSKEEILESDMRVAIMSELIEARYEQGISQKKLEEV
                     SGVSQPVIARMETGESSLQLDTVLKVLTSLGKTLAVVPLEQGKS"
     gene            11714..13963
                     /gene="metE"
                     /locus_tag="VQ543_001422"
     CDS             11714..13963
                     /gene="metE"
                     /locus_tag="VQ543_001422"
                     /EC_number="2.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-methyltetrahydropteroyltriglutamate--
                     homocysteine S-methyltransferase"
                     /protein_id="HET2612134.1"
                     /translation="MSTTIIGFPRLGEFRELKFTTEKYFRKEISEEELLAAAKDLRAK
                     HWNIVKEKGITEIPSNDFSHYDNFLDAAFLFNVVPASVQNLDLSDLERYFALGRGYQG
                     EKGDVRALPMKKWFNTNYHYIVPKFEKDTQVKLAGHKIFDEFQEAKELGLNTRPVLVG
                     PFTFLQLSDFEEGVKADDFVDSLVAAYQEVFAKLAELGATRIQLDEAALVKDLTAEEK
                     ALFLNLYNKLLADKKGLEVLLQTYFGDVRDVYADLVNLPVDAIGLDFVEGKKTLELVK
                     GGFPADKTLYVGIVNGKNIWRNNYEKSLAVLEQIPAENIVLTSSCSLLHVPFTTANEE
                     FEPALLNHFAFAVEKLDEIRDLDAIRNGQGSEALAANKELFATERVGENAELRARIAG
                     LTDADYTRLPAFAEREAIQEEAFKLPALPTTTIGSFPQTKEVRAKRLAYRKGELSQKE
                     YDAFLAETIDEWIKWQEDIDFDVLVHGEFERNDMVEYFGQNLSGYLFSKNGWVQSYGM
                     RGVKPPIIWGDVTRLNPITVKWSSYAQSRTNKPVKGMLTGPVTILNWSFPREDISIKD
                     STLQIALAIKDEVLDLEAAGVKIIQIDEAALREKLPLRRSDWYEDYLDWAIPAFRLVH
                     STVASDTQIHTHMCYSEFTDIIPAIDNMDADVISFEASRSNLEILDELKAKNFQTEVG
                     PGVYDIHSPRVPNEGEIDNTIEAILAKVPSKKVWINPDCGLKTRGIPETKESLIRLVE
                     AAKAAREKL"
     gene            14027..14893
                     /gene="metF"
                     /locus_tag="VQ543_001423"
     CDS             14027..14893
                     /gene="metF"
                     /locus_tag="VQ543_001423"
                     /EC_number="1.5.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000089969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate reductase [NAD(P)H]"
                     /protein_id="HET2612135.1"
                     /translation="MSRQTPSLSFEVFPPNPAVGNGNIISALQDMQELAPHFISVTAS
                     NNKFNIKETTVRLADFIQNDLAIPTIAHLPAIYLTKDKVAETIADLDKVGVQKILALR
                     GDIIPDVEPQKDFRYATDLIEFIKEQAPHFDIIGACYPEGHPDSPNQISDIQNLKKKV
                     DAGCSSLVTQLFFDNERFYDFQDKCILAGIDVPIHAGIMPILNRNQALRLLKTCENIH
                     LPRKFKAILDKYEHDPESLRAAGLAYAVDQIVDLVTQDVAGVHLYTMNNADTAKYIHQ
                     ATHALFNHQSLG"
     gene            15578..17791
                     /gene="pnp"
                     /locus_tag="VQ543_001424"
     CDS             15578..17791
                     /gene="pnp"
                     /locus_tag="VQ543_001424"
                     /EC_number="2.7.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001854499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyribonucleotide nucleotidyltransferase"
                     /protein_id="HET2612136.1"
                     /translation="MAKQVFQTTFAGRELIVETGQVAKQANGSVVVRYGESTVLTAAV
                     MSKKMATGDFFPLQVNYEEKMYAAGKFPGGFMKREGRPSTDATLTARLIDRPIRPMFA
                     EGFRNEVQVINTVLSYDENASAPMAAMFGSSLALSISDIPFDGPIAGVQVGYVDDQII
                     INPSQEQAEQSLLELTVAGTKHAINMVESGAKELSEEIMLEALLKGHEAVKELIAFQE
                     EIVAAVGKEKAEVELLHVDAELQAEIIAAYNSDLQKAVQVEEKLAREAATQAVKDQVT
                     AVYEEKYADHEEFDRIMRDVAEILEQMEHAEVRRLITEDKVRPDGRKVDEIRPLDAVV
                     DFLPRVHGSGLFTRGQTQALSVLTLAPMGETQIIDGLDPEYKKRFMHHYNFPQYSVGE
                     TGRYGAPGRREIGHGALGERALAQVLPSLEEFPYAIRLVAEVLESNGSSSQASICAGT
                     LALMAGGVPIKAPVAGIAMGLISDGNNYTVLTDIQGLEDHFGDMDFKVAGTRDGITAL
                     QMDIKIQGITAEILTEALAQAKKARFEILDVIEATIPEVRLELAPTAPKIDTIKIDVD
                     KIKIVIGKGGETIDKIIAETGVKIDIDEEGNVSIYSSDQDAINRAKEIIAGLVREAKV
                     DEVYRAKVVRIEKFGAFVNLFDKTDALVHISEMAWTRTNRVEDLVEIGDEVDVKVIKI
                     DEKGRIDASMKALLPRPPKPEHDEKGEKSERPHRPRHHKDHKPKKEFTETPKDSE"
     gene            17807..18424
                     /gene="cysE"
                     /locus_tag="VQ543_001425"
     CDS             17807..18424
                     /gene="cysE"
                     /locus_tag="VQ543_001425"
                     /EC_number="2.3.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000539958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine O-acetyltransferase"
                     /protein_id="HET2612137.1"
                     /translation="MGWWRETIDIVKENDPAARTTLEVLLTYPGVKALAAHRLSHFIW
                     KHGFKLLARMHSQFWRFWTQIEIHPGAQIDSGVFIDHGSGLVIGETAIVEKGVLLYHG
                     VTLGGTGKDCGKRHPTVRKGALISAHAQVIGPVEIGENAKVGAAAVVVADVPSDVTVV
                     GIPAKIVRLHGKKDEPVIHEVEEKREYYVNKLEQAKDASHRSSGL"
     gene            18436..19320
                     /locus_tag="VQ543_001426"
     CDS             18436..19320
                     /locus_tag="VQ543_001426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET2612138.1"
                     /translation="MIQVRNKLSQEELSEAKKVINCCQNYDGTYRDPYLSNMLNFDPN
                     MPAFFLYYEKGELVGLLTVYADDQDVEVTILVHPGHRRQGIARALFTSFERETASFPI
                     RSVTFQTERIFLENHPDFASNWGLIEDEETETWLGKDRRPYPLANVSHIEVLLADSSY
                     QDQISQLKFQAFSEEHESREVVDRYVAEALKDPESRLYILLKDGQVIGTCTVDLSTNT
                     NYFYGLAISEPERGKGYGSYLAKSLVNQLIEQNDKEFQIAVEDSNVGAKRLYEKIGFV
                     KQTQVVYLNEKGARDSEV"
     gene            19402..20745
                     /locus_tag="VQ543_001427"
     CDS             19402..20745
                     /locus_tag="VQ543_001427"
                     /EC_number="6.1.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002916477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine--tRNA ligase"
                     /protein_id="HET2612139.1"
                     /translation="MIKIYDTMSRDLREFVPIEDGKIKMYVCGPTVYNYIHVGNARST
                     VAFDTIRRYFEYRGYEVAYISNFTDVDDKIINRAREEGITPQEVADKYIAAFREDVTA
                     LGVKPATRHPRVVEFMADIIRFVEGLIEKGFAYESQGDVYFRVEKSHNYAKLANKTLE
                     DLELGASGRTDEETARKENPVDFALWKSSKPGEISWDSPWGPGRPGWHIECSVMSTEI
                     LGDTIDIHGGGADLEFPHHTNEIAQSEAKTGKAFANYWMHNGFVNIDNVKMSKSLGNF
                     ITVHDALKTLDGQVLRFFFATQHYRKPINFTEKAVRDAETNLKYLKNTYEQPFTGNVD
                     AQELQNFKDKFVAAMDEDFNAANGITVVFEMAKWINSGNYDASVKQALADMLEIFGIV
                     FVEEVLDAEIEDLIQKRQEARANRDFATADQIRDQLVTQGIKLLDTKDGVRWTRD"
     gene            20738..21124
                     /locus_tag="VQ543_001428"
     CDS             20738..21124
                     /locus_tag="VQ543_001428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mini-ribonuclease 3"
                     /protein_id="HET2612140.1"
                     /translation="MIDVNLINGIALAFEGDAVYSMYIRRHLILKGMTKPNKLHQEAT
                     KYVSAKAQARLISLMLEEQILTEKEEEIYKRGRNTNSHTKAKNADVVTYRMSTGFEAV
                     MGYLHMTENLERLESLVSWCIQKVEG"
     gene            21128..22012
                     /locus_tag="VQ543_001429"
     CDS             21128..22012
                     /locus_tag="VQ543_001429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PucR family transcriptional regulator"
                     /protein_id="HET2612141.1"
                     /translation="MRAKELQDWFPEARISDQPVEKEGYLTLPLASQQWILLEEAGLS
                     EREKQLVALLTQQEQARSLNPWYSYLVEGKGQAPQVFKKIQLVYCHLSYFQQENLASW
                     LDMMRTLFPNCQTVLQVGAQDYVFVLQQDKYTSVRDILSDMIEAVEYDFGLRLSIMLG
                     QVWSQTGHQALSDLIKAERDLFKTWWRQGHQGVHTFSQLYLWSMGERLVDLKPIKECL
                     HQMILDQDQIQEIILSLWENSAVLTKTAQQLYLHRNSLQYKIDKWEELTGLQLKELTD
                     LTLCYQLILGSLSTIVGL"
BASE COUNT         6764 a         3965 c         4861 g         6427 t
ORIGIN      
        1 accccaaaag ttagattttt tctgtctaac ttttggggtg tagttcacag ttgaagagcc
       61 agaaaattaa agtgtctttt actcaatcaa aaatagtaac gcctattctt ttggtgaata
      121 agactattgt ttggtatggt gcaatgccat tattagggaa ggtagatgag atgaccatat
      181 tacgtttgga atcagctagt atagtttctg aactagtggc aggtttacga tagagaaaat
      241 ttttaaaaat ttctatgtat gattttcatt tctttagtga gactgttgcc attatcacat
      301 tcgaatcaca caaaataaaa aaatttctac aagtacttga caaatagatt gaaatatcat
      361 aaaatgaaaa tggttacaga gttattaatt atttaagctt catgtcacca ttaaaaattg
      421 aaataaaagg atgttatcac taatacaagt gagcaggaac ctatttaatc acatcggaag
      481 aagtttcttg atgtttttaa gtaggttcct tttattttaa aagggaaatt ttatgatcat
      541 aaaacgaata ctaaaccaca atgccgtaat tgcgcaaagt aaaaaagata tcgatattct
      601 tctttttgga aggggcatag cttttggaag aaaaactgga gataaagtaa atccaattga
      661 tattgagaaa agtttttttc tcaaaaatag agataatatg acccgtttta cagagatgtt
      721 tattaacgtt cctttggagt tggtgtacat caccgaaaaa ataattaacc taggtaaaat
      781 aacattgggt aataattttg atgaaattat ctatattaat ttaacggatc atatttcttc
      841 gagcatagaa cgttataaag aagggattat tatttcgaat cccctacgct gggaaatatc
      901 gaaatattat aaagaagaat ttgaacttgg gaaaagggct ttacaaataa taaaaaaaga
      961 gttaggtatt gaacttccaa ttgacgaagc tgcattcata gcgctacatt ttgttaatgc
     1021 taatttagaa aataattttc aagagtcgta taaaatcact gaaataatta tgggaattga
     1081 gaaaatcatt caagatttct attgtactga gtttaaccaa gattctattg attattatag
     1141 attcataact catataaaat tatttgctca tcgcttggtt gaaaatacaa cttattgtga
     1201 cgatgatgat gaagacttgt tagcattaat gaaaaataaa tatcctagag aatatgaatg
     1261 tggtgaacag gtggcaatgt ttatacaaac tgagtacaat tatttgctga cttctagtga
     1321 attagtttat ttgatggctc atattcgtcg cttaacaaaa aatttagatt aatagaatag
     1381 gagaatacca tgagttataa agatacggta caaaaaatcc tcgatgtaat tggaggtgaa
     1441 aaaaatgtca atagagttac ccattgtgta acacgtttaa gattagaatt aaaagatgaa
     1501 aatttagtca atgatgatga tgtgaagaag ataccagatg taataggtat tatgaaaaag
     1561 aatggacaat atcaaattat acttggtaat gatgtagcta attattataa agaattcgtt
     1621 aaacttggca attttgaatc cgattcagtt gttcaagggc acaaagggaa tattttagaa
     1681 agaatcattg agtatatcgc tggttccatg actccaatca ttccagcaat gttaggggga
     1741 ggtatgttga aagtcttggt aatcatttta ccaatgcttg gtatattgca atcagattct
     1801 cagactattg cttttttgac attttttggg gatgctccat attatttctt accgctgtta
     1861 ttagcttatt ctgcatcaca aaaattaaaa gtaacatcta cattagctat gtctgtagca
     1921 ggtgtacttc tccatccaaa ttttgttcaa atggtgcaat cagggaatcc tcttagttta
     1981 tttggtgcac ctgtgacacc agctagttat ggttcatcag tcgttccaat tcttattatg
     2041 gtttggttga tgaaatatat tgaaaaaata attgctaaat taacaccagc tattactaag
     2101 agttttttgc aacctacgct agtattatta gtatcaagct gtattgcctt agttgtagtc
     2161 ggacctattg gagtaattgt tggtgaagga ttatcaaatc tagttgggca aatgtatggt
     2221 gtagctggat ggcttacatt agctattctt ggtgctatta tgccatttat tgttatgact
     2281 ggaatgcatt gggcttttgc acctattttt ttggcggcat ctattgctac tccagacgta
     2341 ttaattcttc cagcaatgtt agggtcaaac ttagctcaag gggctgcttc gatggctgtt
     2401 gcattaaaga gtaaaaataa taatacaaaa caaattgctt ttgcagcagg tttctcagcc
     2461 ttacttgcag ggattaccga acctgcatta tatggtgtga ctttaaaata taaaaaaccg
     2521 ctttatgcag ctatgattgg tggtggatta gcgggattat ttgcaggtct tactagtgtt
     2581 aaagcatatc tatttgctgt cccatctttg atagcgttgc ctcaatttat ttattctgat
     2641 gtgccatcaa atattgtaaa tgctttaatt gtggcggtca tttcggttgt tattaccttt
     2701 gtattagctt atatatttgg aatcgatgaa gaagagagtt ctagcaattt agaagttaaa
     2761 gctggagttt caaataaaaa aatgatattt tctcctatat caggagaaat cattccgtta
     2821 agcgatgtcc aggataaaac attttcagat aaattaattg gagacggagt agcgattatc
     2881 ccaagtgaag gtaaggttta tgcaccattt gatgggaaaa ttacaaatat ttttccgact
     2941 aagcacgcaa ttggattgaa gagtgatgag ggtgttgagt tactaattca tattggatta
     3001 gatactgttg agctaaaagg tcaaggtttt attagtcatg tagaagaagg agacagagtt
     3061 ttcaaaaatc agttgatttt tgaaatgaac ttgaatttaa tcaagactaa aggctacgaa
     3121 acagttacac cagtaattgt aacgaatacc aatgattttc tagatgtatt agtattacct
     3181 aataatcaga caatcgagca ttctaaggaa ttactggtaa tattataatg gaggaaagtt
     3241 atgaccattt ttccagatga ttttctttgg ggtggagcgg ttgcagctaa tcaagtagag
     3301 ggagcatata atgaagatgg taagggctta tcagttcagg atgtgttacc caaaggtgga
     3361 ttaggagaag caacagaaaa tcctacagaa gataacttaa aattgatagg tattgatttt
     3421 tatcataaat ataaggaaga tatatccttg ttttctgaaa tgggctttaa tgtttttcgt
     3481 acttctattg catggagtag aatttttcca aaaggagatg aggaagaacc taacgaagct
     3541 ggtttgaaat attatgatga attatttgat gaactacatg ctcacgggat agaaccactt
     3601 gtaactcttt cacactatga gactccatta tatttagcaa gaaaatatca tggatggatt
     3661 gataggagaa tgattcattt ttatgaaaaa tttgctcgaa cagttttaga aaggtataaa
     3721 gataaagtta aatattggct tacatttaac gaagtaaact ctgttttgga attaccgttt
     3781 actagtggag gaatagatat acctaaggag aatctttcga aacaagaatt atatcaagct
     3841 atacatcatg aattagtcgc ctcgagtttg gttacaaaaa ttgctcgtga gattaattca
     3901 gagtttaagg tggggtgtat ggtattagct atgccagctt atccaatgac tccaaatcca
     3961 aaagatgtat gggcgactca tgagtatgag aatctaaatt atctattttc agatgtgcat
     4021 gttagaggtt attatccgaa ttatgcaaaa agatatttta aggaaaatga cattaacata
     4081 gagtttgcag ctgaagatgc agagttatta aaaaattata ctgtagattt tttatccttt
     4141 agctattaca tgagtgtgac tcaatctgct attccaacac agtataattc aggagaaggg
     4201 aatattattg gtggtttagt aaatccttat ttagagtctt cagagtgggg atggcaaatt
     4261 gatccaattg gactacgtat aattttaaat agatattatg accgttatca aatcccatta
     4321 tttatagtag aaaatggatt aggtgctaaa gatcaactaa taaaagatga acttaataac
     4381 ttaaccgtcc aagatgatta tagaattcag tatatgaaag aacatttatt gcaagttgct
     4441 gaagctctac aggatggtgt tgaaattatg ggctatacgt cttggggatg tattgactgt
     4501 gtttctatgt ccactgcaca actttctaaa aggtacggtc tcatttatgt tgatcgaaat
     4561 gatgatggaa atggcacatt caatcgatat aagaaaatgt cctttacttg gtataaagga
     4621 gtgattgaat caaatggaga atccttattc aaatagtttg tttattgatg attagatatt
     4681 atcacggtta aggcaacatc tcattaaata taaaataaag aggtttggaa gacatcaaat
     4741 tctaaacctc tttattttat agggggatta attaatttaa ttttgttaca gagagccgat
     4801 tataaatagt taacttagga tagattggtt atatatagta gactgaatct aaaatagtac
     4861 gaaacaattg ctaaaacatt tatagaaatt aattttactt tcccaatcga tttgttttca
     4921 tcttatttca atccgctata aagttagata agaataagct aacaagcaga agtaagatag
     4981 gtcttgcaag aatggtaaaa atctgataaa ctaagtagta attgaatagg aatctgaaag
     5041 actagtagcc caagggaagt atatcaggga ggagagccgt gactgcaagc tctctatatg
     5101 aaagctgggt gaattcactt gcgcatggat ttagaaatga aggtctgact tgtcagatga
     5161 aaacggatgg taccgcgtgt caacgctccg agtggagttt ttggcatgtg gttttctttt
     5221 tatctacgag agactgatgg aggaaatatg tcaactattg aagaacaatt aaaagcgctt
     5281 cgcgaagaaa cgctggctag cttgaagcag attactgctg gaaatgaaaa agagatgcaa
     5341 gatttgcgtg tctctgtcct tggtaaaaag ggttcgctca ctgaaatcct caaagggatg
     5401 aaagatgttt ctgctgagat gcgtccaatc atcgggaaac acgtcaatga agctcgtgat
     5461 gtcttgactg ctgcttttga agaaacagct aagctcttgg aagaaaagaa agtcgcggct
     5521 caactggcta gcgagagtat cgatgtgacg cttccaggtc gtccagttgc gactggtcac
     5581 cgtcacgttt tgacacaaac cagtgaagaa atcgaagata tcttcatcgg tatgggttat
     5641 caagtcgtgg atggttttga agtggagcaa gactactata actttgaacg tatgaacctt
     5701 ccaaaagacc acccagctcg tgatatgcag gatactttct atatcactga agaaatcttg
     5761 ctccgtaccc acacgtctcc agttcaggcg cgtgctatgg atgcccatga tttttctaaa
     5821 ggtcctttga agatgatctc gccagggcgt gtcttccgtc gcgatacgga cgatgcgacc
     5881 cacagtcacc aattccacca aatcgaaggc ttggtagttg ggaaaaatat ctctatggct
     5941 gatcttcaag gaacgcttca gttgattgtc caaaaaatgt ttggtgaaga gcgtcaaatt
     6001 cgtttgcgtc catcttactt cccattcaca gagccatctg ttgaggtgga tgtttcttgc
     6061 ttcaagtgtg gtggagaagg ctgtaatgta tgtaagaaaa caggttggat cgaaattatg
     6121 ggggccggta tggttcaccc acgtgtcctt gaaatgagtg gtatcgatgc gactgtatac
     6181 tctggctttg cctttggtct tggacaagag cgtgtagcta tgctccgtta tggaatcaac
     6241 gatatccgtg gattctacca aggagatgtc cgcttctcag aacagtttaa ataatgatta
     6301 gaaaagtaga aatggcagat gttgaggtgt tggctaaaat tgccaaacaa gcctttcgtg
     6361 aaacctttgc gtatgataat acggaagagc agttacagga atactttgaa gaggcttata
     6421 gtctgaaaac tttgtcaact gagttgggaa atcctgactc tgaaacctat ttcattatgc
     6481 atgaggagga gatagctggt tttctcaaag tcaactgggg aagtgctcaa actgagagag
     6541 aattagagga cgcttttgaa attcaacgcc tctatgtgct acaaaaattc caaggatttg
     6601 gactaggtaa gcaactgttt gaattcgcac ttgaacttgc tacaaaaaat agtttttctt
     6661 gggcttggct aggtgtttgg gagcataata caaaagctca agcgttttat aaccgatatg
     6721 gttttgaaaa atttagccaa catcatttta tggttggtca aaaagtagat acggattggt
     6781 tactgagaaa gaaattaagg taagaagaga attcttctat tgaaatgata ggaaaggaaa
     6841 agaaccagtg tggcaatggt cattctggag aactaaatta tgcttgtatc ttataaatgg
     6901 ttaaaagaat tggtgggcat tgatgtgcca tcacaggagt tggctgaaaa aatgtcaacc
     6961 acagggatcg aggtcgaagg tgtcgaatca ccagctgccg gtctttcaaa aattgtcgtc
     7021 ggtgagatct tgtcttgcga agatgtgcca gaaactcacc ttcatgtttg tcaggttaac
     7081 gttggcgaag aagaagagcg tcagatcgtt tgtggtgccc caaatgtgcg tgcaggcatc
     7141 aaggttatgg tggctcttcc gggagctcgt atcgctgaca attacaaaat caaaaaagga
     7201 aaaatccgtg gcttagagtc acttggaatg atctgttcac ttggtgaatt gggtatttct
     7261 gactcagttg tacctaagaa attcgcagat ggtattcaaa ttttgccaga aaatgccgtt
     7321 ccaggtgagg aagtcttttc atatctagac ttggatgatg aaatcatcga actttctatc
     7381 acaccaaacc gtgcagatgc cctttctatg cgtggagtgg ctcacgaagt ggcagccata
     7441 tatgacaagg cagtcaactt taaagaattt actttgacag aaacaaatga agctgcgaca
     7501 gatgcccttt ctgtgggcat tgagacagac aaggcgcctt actatgcagc tcgtatcttg
     7561 gacaatgtga ctatcgcacc aagtccacaa tggttgcaaa accttctcat gaacgaaggc
     7621 atccgtccca tcaataacgt tgtagacgtg acaaactaca tcctgctcta ctttggtcaa
     7681 cctatgcatg cttttgactt ggacacattt gaagggactg acatccgtgt gcgtgaagcg
     7741 cgtgctggtg aaaaattggt gaccttggac ggtgaagaac gtgacttgga cgtgaatgac
     7801 ctagtcatca ctgttgcaga caagccagta gcccttgcag gtgtcatggg tggtcaagca
     7861 acagaaatct ctgaaaaatc tagtcatgtt gtccttgaag ctgctgtttt caatggcaaa
     7921 tctatccgta agacaagtgg tcgcctgaac cttcgttctg agtcatcttc tcgctttgaa
     7981 aaaggaatta atgtggcaac agttaatgaa gcccttgatg cggcagctag cctgattgcg
     8041 gaacttgcag gtgcgacggt gcgtaagggt atcgtttcag cgggtgagct tgatacttca
     8101 gatgtagaag tttcttcaac tcttgctgat gttaaccgtg tcctcggaac tgagctgtct
     8161 tatgctgatg tcgaagacgt cttccgtcgt cttggctttg gtctttctgg aaatgcagac
     8221 agctttacag tcagcgtacc acgtcgtcgt tgggatatca caatcgaagc tgatctcttt
     8281 gaagaaatcg ctcgtatcta tggatatgac cgcttgccaa ccagccttcc aaaagacgat
     8341 ggtacagctg gtgaattgac tgtgacacaa aaactccgcc gtcaagttcg taccattgct
     8401 gaaggagcag gtttgacaga aatcatcacc tatgttctaa caactcctga aaaagcagtt
     8461 gagtttacgg ctcaaccaag taaccttacg gaactcatgt ggccaatgac tgtggatcgt
     8521 tcagtcctcc gtcaaaatat gatttcaggt atccttgata ccgttgccta caacgtggct
     8581 cgtaagaata aaaacttggc cctttacgag attggaaaag tctttgaaca aacaggtaat
     8641 ccaaaagaag aacttccaaa tgaaatcaac agttttgcct ttgccttgac aggcttggtt
     8701 gctgaaaaag atttccaaac agcagcagtt ccagttgatt tcttctatgc taaaggaatc
     8761 ctagaagcgc tctttactcg cttgggacta gaagtgacct atacagcaac agctgagatt
     8821 gccagccttc acccaggacg tacagcagtc atttcactcg gtgaccaagt tcttggtttt
     8881 cttggccaag tgcatccagt cactgctaag gcttacgata ttccagaaac gtatgtggct
     8941 gagctcaacc tttcagtcat cgaagctgcc cttcaacctg ctgctccatt tgtggaaatc
     9001 acgaaattcc cagcagtcag ccgtgacgtt gcccttctcc tcaaggcagc agtaactcac
     9061 caagaagtta tagatgctat ccaagctgcc ggcgtgaaac gtttgacaga tatcaaactc
     9121 tttgacgttt tctcaggtga gaaattggga cttggtatga agtcaatggc ttatagcttg
     9181 accttccaaa atccagaaga cagcttaacg gacgaagaag tcgcacgcta catggaaaaa
     9241 atccaagcat cgcttgaaaa aaaagtgaac gcagaagtgc gttaaacgat agtaggatac
     9301 aaattccccc tctagtttat gaacactaga ggggtgattt tatataatac tcaatgaaaa
     9361 tcaaaaagca aactaggaag ctagccgtaa gctgtacttg agtactgtaa ggcgaggctg
     9421 acgtggtttg aagagattgt cgaagagtat aaaataatta aaatgtgatt tctgtaaaaa
     9481 tacatctatg atcagagttt tgaaaactta caatgtctaa atctttaaca tagtagtggt
     9541 ttttaggcaa taaaatatga tctattgttg cattaaaaag ttttggactt tggctattcc
     9601 aagttcctct ttcaaaaggt ggtagtacat ttaatgcgtc cctatgagag cttatttttg
     9661 caagtgctcc atgacgcata gttgcattaa aatcatctgc aataatagcc tttggatatt
     9721 ttgaagccaa ttgattatga atgatgttta agtcttgctt ccagatttcc attaaacctg
     9781 gcagaggagg agcagtatgc aaggcaatga tatctggtat attttgtttt ctcgaatgta
     9841 atacaattgt cccgaaccgt gttgtatgaa aagttttagc ttctgtatag aaaccataac
     9901 ttttcttgac aatcacagtc acaggagcta ttccactatt ggtaggtgga gaagtgaaaa
     9961 tatcatagtt ggccatagaa agtccaactt gatgaaacaa tagtttgatt ctctggtttt
    10021 cttgctcacc tctgatattg gtagctagtt cagggaatat agccatatcg gcgtcaaaat
    10081 ggctaaaaat tcgctcaata tgttgtgctt ctatttgatt agcgacgttc caagttacta
    10141 attttaaggt tttagtctta tttgatgcag aagaaagggt tttatctgtt ccgaataata
    10201 gtaatatgag cgatagtaag agcaaaatgc cagagtaaaa ccgtatttgt ttatttttct
    10261 tgtaaaaaga tagggaaaaa aatacgaaac ttaaaatagc agccatagtt gcagtagcta
    10321 aggggaaggc ataaatctgt gccaagatag gtctggtaga tagccaaata ttaagattag
    10381 aagatggaaa aaaagaataa gttatgatag ggataacaaa gagaatgacc gaaagggcag
    10441 agagaaatgt tttaatcatt gtgtgagtac ctcaatttgc aatggttgct cggagctaat
    10501 gtgactttgt gactttactt gattgatatt ctttttcttg tcttcctcat agattaagta
    10561 caacccaagt aaaaaaagtc caatttaaga ttgaaatgat taaaaggcac agaaatgcaa
    10621 gacaattata ctacaaaagg caaacatttg acaatcgata gccgtcgctt aatcgaaaga
    10681 tggaaaaaag aagggaaatc aaatagagaa attgcctctc tgcttggaaa agttcctcaa
    10741 actatccaca ctgaaatcaa gcgtgggaca gtccgacaat gtcttggaaa agggcgcttc
    10801 aaagaggttt attctgccga ctatgctcaa cagtcttatg aaaacaatcg caagcgctcg
    10861 gtcaagaaat caagcttgac caaggaacta aaggaaaaga ttctccacta tcataaccaa
    10921 aaattttcgc ttgaaatgat ggtgatggct aaaggggtta acgtgggaat ttcaaccatt
    10981 tactattgga ttcatcgtgg aaaattgggg ttaagcaagc aggatctgct ttaccctaga
    11041 aaaggaaaag cgcttaagaa acaggctagc accaacttta aacctgctgg tcaatctatc
    11101 gaatcataat tcgctcattc ttttaaaaat acatagacgt aaaagaaaga gggttaagtg
    11161 atgaagaata gtgctattgg gagtaattgg aaggatgtcc atctgagctc tttagcaagg
    11221 aggaaatcct tgaaagtgat atgcgagtgg ctatcatgag cgagttgatt gaggctaggt
    11281 atgaacaagg aatcagtcag aaaaagctgg aagaagtcag tggagtgagt caacctgtca
    11341 tagctaggat ggaaacagga gagagcagtc ttcagttgga tacggtctta aaagttctaa
    11401 ccagtctagg aaagacacta gcagtcgttc cacttgaaca ggggaaaagt tgactagaat
    11461 cagttatagt cttttctaat aacaggtcat agtcacttat aagaattact aataacatgt
    11521 tttagtattc taattggaat atagctgtaa agtaagaatt acaaaggatt tgagacgttt
    11581 gcttcaagtc tttttctttt gtccgaaaca gatatatagt ttcaaactat atcaaaccct
    11641 aattttttac aattatacag acgctttctt ttctgttaag atagtttcaa caacaaattt
    11701 tggaggacac atcatgtcaa ctacaatcat cggtttccct cgtttgggcg aattccgtga
    11761 attaaaattt acaactgaaa aatactttag aaaagaaatc tcagaagaag aacttttagc
    11821 agcagcaaaa gacttgcgtg ctaaacactg gaacattgtc aaagaaaaag gcatcactga
    11881 aattccatca aatgactttt ctcactatga taacttccta gatgcggctt tccttttcaa
    11941 cgtggtgcct gcatccgttc aaaacttgga cttgtctgac cttgagcgct acttcgcttt
    12001 gggacgtggt taccagggag aaaaagggga cgttcgcgcc cttccaatga agaaatggtt
    12061 caacactaac taccactaca tcgttcctaa atttgaaaaa gacactcaag taaaattggc
    12121 tggtcacaag attttcgatg agttccaaga agccaaagaa cttggattga acactcgtcc
    12181 tgttcttgta ggtcccttca ctttccttca attgtcagac tttgaagaag gcgtgaaagc
    12241 agacgacttc gtagatagct tagtggctgc ttaccaagaa gtttttgcta aattggctga
    12301 acttggtgcg actcgcatcc aattggatga agcggctctt gtaaaagact tgacagctga
    12361 agaaaaagct ctcttcttga acctttacaa caaactcttg gctgacaaaa aaggtcttga
    12421 agtcttgctt caaacttatt tcggtgatgt tcgtgacgta tacgctgacc ttgtaaactt
    12481 accagtagat gctatcggtc ttgactttgt tgaaggtaag aaaactcttg aactcgttaa
    12541 aggtggcttc ccagctgaca agactctcta tgtaggtatt gtcaatggta aaaacatctg
    12601 gcgcaacaac tacgaaaaga gcttggctgt tcttgagcaa attccagctg aaaacatcgt
    12661 tttgacaagc tcttgctcac ttcttcatgt gccatttaca actgctaatg aagaatttga
    12721 accagcactc ttgaaccact ttgcctttgc agttgaaaaa ttggatgaaa tccgtgactt
    12781 ggatgctatc cgcaatggtc aaggttcaga agctcttgca gccaacaaag aactctttgc
    12841 gactgagcgt gttggtgaaa atgctgaact tcgtgcgcgt atcgctggct tgacagacgc
    12901 agactacact cgtttgccag cctttgcaga acgtgaagct atccaagaag aagctttcaa
    12961 acttccagct cttccaacaa caacgattgg ttcattccct caaacaaaag aagttcgtgc
    13021 caaacgtttg gcttaccgta aaggtgaatt gtctcaaaaa gagtacgatg ctttccttgc
    13081 tgaaacgatt gacgaatgga tcaagtggca agaagatatt gactttgatg tccttgttca
    13141 cggtgaattt gagcgtaatg acatggttga gtacttcggt caaaacttgt caggatacct
    13201 cttctctaaa aatggatggg tacaatcata cggtatgcgt ggggtaaaac caccaatcat
    13261 ctggggtgat gtcactcgtc ttaaccctat cactgttaaa tggtctagct atgcacaaag
    13321 tcgtacaaac aaacctgtta aaggtatgtt gactggacct gttaccatcc ttaactggtc
    13381 attcccacgt gaagacatct ctatcaagga ttctactctt caaatcgccc ttgctatcaa
    13441 ggatgaagtg cttgaccttg aagctgctgg tgtgaaaatc atccaaattg atgaggctgc
    13501 tcttcgtgaa aaattgccac tccgtcgtag tgactggtac gaagattacc ttgactgggc
    13561 aattcctgcc ttccgcttgg tacactcaac agtagcgtca gacacacaaa tccacactca
    13621 catgtgttac tcagaattta cagatatcat cccagctatc gataacatgg atgcagacgt
    13681 tatttccttt gaagccagcc gttcaaacct tgaaatcttg gacgaactca aagcgaaaaa
    13741 cttccaaaca gaagtgggac ctggggttta cgatatccac tcacctcgtg taccaaatga
    13801 aggcgaaatc gacaacacaa tcgaagccat ccttgctaaa gtgccaagca agaaagtttg
    13861 gatcaaccct gactgtggtt tgaaaacacg tggtatccca gaaacaaaag aaagcttgat
    13921 ccgccttgtt gaagcagcta aagctgcgcg tgagaaattg taagattgga tttctctcca
    13981 tacagtggtt gttcaaaaag aaatcaacta gaaaaggtta ttacatatgt cacgccaaac
    14041 accgtcactc tcatttgaag tgttccctcc aaacccagcc gtgggtaatg gtaacattat
    14101 ttcagccttg caggatatgc aggagttggc tccccatttt atcagtgtaa ctgccagcaa
    14161 taataaattt aatatcaagg aaacgacggt tcgtttggct gactttatcc aaaatgactt
    14221 ggcgattccg accattgccc acttgccagc tatttatcta actaaggaca aggttgctga
    14281 aactattgct gacttggaca aagttggggt tcagaaaatc ttggctcttc gtggggatat
    14341 tattccagac gtagaaccac aaaaggattt ccgctatgca accgacttga ttgagtttat
    14401 caaggaacaa gcccctcact ttgatattat tggagcttgc tatccagaag ggcatccaga
    14461 ttcgccaaat cagatttcag atattcaaaa tcttaagaag aaagtggatg caggctgttc
    14521 gagcctcgta actcagctct tctttgacaa tgagcgcttc tatgattttc aggacaagtg
    14581 tatcttggct gggattgatg ttcctattca tgcaggaatt atgccaattc tgaatcgaaa
    14641 tcaggctctc cgactcttga agacttgtga gaatatccat cttccacgca aatttaaagc
    14701 catcttagac aagtatgagc atgaccctga gtcgctcaga gcagcaggac ttgcctatgc
    14761 agtggaccaa atcgtggact tggtaactca ggatgttgcc ggtgtgcatc tctatacgat
    14821 gaataatgct gatacagcaa aatacatcca tcaagcaacc catgccttgt ttaatcacca
    14881 gtctctagga taataaaagc aaaccattct tctcaggtga ggggaatggt tcctttttaa
    14941 tggtaaagac ctcacttttt aagaaaaata tgataaaata gattctgtac gtacttgata
    15001 caaagatgaa ggtattaaat aatacaatgc atttaaactg taagatttaa cgacacgagt
    15061 gagtcaaatc gatgttattt gacgaaagag ttagtaaagc atttagctaa tcgcccgata
    15121 gcgattagcg tgaaaggttt agatacttta atattaaacc tttctaatga tgtatcttga
    15181 aaactgaaca cgcctacaac tctgtggaaa aagataaatc tgcctaggag cagtcgctcc
    15241 gtcgttcgat ttcctatctt cctttgagtt gcttgacggc ttggtatctt gatgacttga
    15301 attttggtct catttcttag gaaaaaagat aagcttccta gcactcgtcg agtgcgacgt
    15361 caccttccta tttttctaca gaaatgttcg gcaagccgaa ccgtccaaaa tatcttgtgt
    15421 aattgaacac ggccgaaaag ctgtgtaaaa aagataaact gtcttgtctt catcgaagac
    15481 ttcgtcagtt tcctattttt actttgcttt tgacgtcctt ggtatcttga tctttgtagg
    15541 caaggcgtat aatttcatca atccaaaggg gattaaaatg gcaaaacaag tgtttcaaac
    15601 gacttttgcg ggtcgtgagt taattgtaga gactggtcag gttgctaagc aagcaaatgg
    15661 ctctgttgtc gtacgttacg gtgagtcaac tgtcttgact gctgccgtta tgtctaagaa
    15721 aatggcaact ggggattttt tcccactcca agtcaactac gaagaaaaaa tgtatgcggc
    15781 tgggaagttt cctggtggct ttatgaaacg tgaaggacgt ccttcaacag atgcgacctt
    15841 gacagcgcgt ttgattgacc gtccgattcg tcctatgttt gcggaaggtt tccgtaatga
    15901 agtccaagtc atcaatacag tgctttctta tgatgaaaat gcatctgcac caatggctgc
    15961 tatgtttggt tcatctttgg cactgtctat ttcagatatt ccatttgacg gaccaattgc
    16021 tggggtacaa gtgggatatg tagatgacca aatcatcatc aacccaagtc aagaacaagc
    16081 agagcaatct cttcttgaat tgacagtagc tggaactaag cacgctatca acatggtaga
    16141 gtctggtgcc aaagaattgt cagaagaaat catgttggaa gcgcttctta aagggcacga
    16201 agctgtcaaa gaattgattg ccttccaaga agaaatcgtt gctgctgtcg gtaaagaaaa
    16261 agcagaagtg gaattgcttc acgtggatgc tgaattgcaa gctgaaatca ttgcagccta
    16321 caacagtgac ctccaaaagg cagttcaagt agaagagaaa ttggcccgtg aagctgcaac
    16381 tcaagcagtg aaagaccaag tgactgccgt ttacgaagaa aaatatgcgg accacgaaga
    16441 atttgaccgt attatgcgtg atgtggctga aatcttggaa caaatggaac acgcagaagt
    16501 gcgacgttta attacagaag acaaggtgcg tcctgatggt cgtaaggtcg atgaaatccg
    16561 tcctttggat gcggttgttg acttccttcc tcgtgtacat ggttcaggtc tctttactcg
    16621 tgggcaaact caagctcttt cagtcttgac cttggctccg atgggagaaa ctcaaatcat
    16681 tgatggtttg gatccagagt acaagaaacg ctttatgcac cactataact tccctcaata
    16741 ttctgtaggg gaaacaggtc gttacggtgc gccaggtcgt cgtgaaatcg gtcacggtgc
    16801 ccttggtgag cgtgctcttg ctcaagtctt gccaagcttg gaagaattcc catacgctat
    16861 ccgtctagta gcagaagttt tggaatcaaa cggttcttca tctcaagctt ctatctgtgc
    16921 gggaactctt gcccttatgg ctggtggtgt gccaatcaag gcgccagtag ctggtattgc
    16981 tatgggactt atctcagatg gaaataacta cacagtattg acagatatcc aaggtttgga
    17041 agatcacttt ggagatatgg acttcaaggt tgcaggtact cgtgatggga ttacagccct
    17101 tcaaatggat atcaagattc aagggattac tgcagaaatc ttgacggagg ctcttgctca
    17161 agccaagaaa gcgcgttttg aaatccttga tgtcattgaa gcaaccattc cagaagttcg
    17221 tctagaattg gctccaactg ctccgaaaat tgatacgatc aagattgatg tggacaagat
    17281 taagattgtc atcggtaagg gtggagaaac catcgacaag attatcgctg aaacaggtgt
    17341 taagattgat atagacgaag aaggaaatgt gtctatctac tctagtgacc aagatgctat
    17401 taaccgtgcc aaagaaatta ttgctggttt ggttcgtgaa gccaaagtgg atgaagttta
    17461 ccgtgctaaa gtcgttcgta tcgagaaatt tggtgccttt gttaacctct ttgataagac
    17521 agatgccctt gttcatatct ctgagatggc ttggactcgt accaatcgtg tagaggattt
    17581 ggtagaaatc ggggatgaag ttgatgttaa ggttatcaag attgatgaaa aaggccgtat
    17641 cgatgcctct atgaaggctc ttctacctcg tccgccaaaa cctgagcatg atgaaaaagg
    17701 tgaaaagtct gagcgtcctc accgcccacg tcatcacaag gatcacaaac ctaagaaaga
    17761 atttacagaa acaccaaaag attcagaata agaaaaggag aaatgtatgg ggtggtggcg
    17821 cgaaaccatt gatatcgtaa aagaaaatga tccagcggcc cgcaccactt tggaggtttt
    17881 gctgacttat ccaggtgtca aggccttggc ggcccaccgt ctctcgcatt ttatctggaa
    17941 gcacggcttc aaactcttag ctcgtatgca cagtcagttt tggcgctttt ggactcagat
    18001 tgagattcat ccaggagccc agattgattc aggtgtcttt attgaccatg gttctggtct
    18061 ggtgattgga gagacagcga ttgttgaaaa aggcgttctt ctctatcacg gagtgactct
    18121 tgggggaaca gggaaagact gtggcaaacg ccatccgact gtacgaaagg gagccctcat
    18181 atcagcccat gcccaagtta tcggacctgt ggaaattggt gaaaatgcca aggtcggtgc
    18241 tgcagcagtt gtcgtagcag atgtacctag tgatgtgacg gttgtcggta ttccggccaa
    18301 gattgtccgt cttcatggta agaaagatga gcctgtcatt cacgaagtcg aagaaaaacg
    18361 agagtattat gtcaataaac tcgagcaggc taaagatgcc agtcacagat cgtctggttt
    18421 gtagaggata cctatatgat tcaagtaaga aacaagttaa gccaagagga gctatctgag
    18481 gcgaaaaaag taattaactg ttgccaaaac tatgacggta cctatcgcga tccctatctc
    18541 tctaacatgc ttaattttga cccaaacatg cccgcctttt tcctttatta tgaaaaaggc
    18601 gaacttgttg gtttattaac tgtctatgca gatgaccaag atgtagaagt gacgatactg
    18661 gttcatccag gtcatcgccg tcaggggatt gcgcgtgcat tgtttactag ttttgagaga
    18721 gaaacagctt ctttccccat tcgatcagtc acttttcaga cagaacgtat ttttttagag
    18781 aatcatcctg actttgccag taactgggga ctaatcgagg atgaagagac agaaacttgg
    18841 ttaggtaagg atagaagacc ttatccgtta gcaaatgttt cccatattga agttttgtta
    18901 gcagatagtt cgtatcagga tcaaattagt caattaaaat ttcaggcatt ttcagaggaa
    18961 catgaatcga gagaagttgt ggatagatat gtcgctgaag ctctgaagga tccagaaagc
    19021 cgactatata ttttgttaaa agacggtcag gttattggga cttgcacggt agatttatcg
    19081 actaatacga attacttcta cggtttagca atatcggaac ctgaacgtgg gaaaggctat
    19141 ggaagctact tagcaaaatc cctcgtcaac caactaattg agcaaaatga caaggaattt
    19201 cagattgcag tggaagatag caatgtaggt gccaaacgtt tgtatgaaaa aattggcttt
    19261 gtcaaacaga ctcaggtggt ttatctgaat gagaaaggag caagggattc cgaagtgtag
    19321 agatattcgg actgaaattt acttgaactt ttagtgatga aactaattgt tcttggattt
    19381 cagctttctt gattatgatt tatgattaaa atctatgaca ccatgtctcg tgatttgcga
    19441 gaatttgtcc cgattgagga cggcaagatc aagatgtatg tttgtgggcc aacggtgtac
    19501 aactatattc atgtagggaa tgctcgttca acggtagctt ttgataccat tcgtcgctat
    19561 tttgagtatc gtgggtacga ggttgcctat atttccaatt ttacggatgt ggatgataag
    19621 attatcaacc gtgccaggga agaaggcatc acgcctcagg aggttgcgga taagtacatc
    19681 gctgcctttc gtgaggatgt gacggccttg ggcgtgaaac ctgcgactcg ccatccgcgt
    19741 gtagtggagt ttatggcaga catcatccgt tttgtggaag gcttgatcga gaaaggcttt
    19801 gcctatgaga gtcaagggga tgtctatttc cgtgtagaaa aatcccacaa ctatgctaaa
    19861 ttggctaata aaaccttgga agatttggag ctaggtgctt caggtcgtac cgatgaagaa
    19921 acggctcgta aggaaaatcc tgtagacttt gctctatgga aatcttccaa accaggtgag
    19981 atttcttggg atagtccttg gggacctgga cgtccgggtt ggcatattga gtgttcagtc
    20041 atgtcgacag agattttagg tgataccatt gatattcacg gtggtggagc tgacctagag
    20101 tttccacacc acaccaatga aattgcccaa tctgaagcta aaacaggcaa ggcttttgct
    20161 aactactgga tgcacaatgg ctttgtcaat atcgacaatg tcaaaatgtc taagtccttg
    20221 ggtaacttca ttacggtaca cgatgccctt aaaactcttg atgggcaagt acttcgtttc
    20281 ttctttgcga cccagcacta ccgtaagcct atcaacttca cggaaaaggc agttcgcgat
    20341 gccgagacca atctcaagta tctgaagaat acttacgaac aaccatttac aggaaacgtg
    20401 gatgcccaag agttacaaaa ctttaaagat aagtttgtag cagctatgga tgaagatttt
    20461 aatgctgcca acggtatcac agttgtcttt gaaatggcca aatggatcaa ctcagggaac
    20521 tatgatgcaa gtgtcaagca agctcttgca gatatgttag aaatttttgg aattgtcttt
    20581 gttgaggaag ttttggatgc agagattgaa gacttgattc aaaaacgcca agaggcgcgt
    20641 gccaatcgtg actttgcgac agcagaccaa atccgtgacc aattggttac tcaaggaatt
    20701 aagctccttg ataccaagga tggagtgagg tggacacgtg attgatgtca atctcattaa
    20761 cgggattgcg ctagcctttg agggagatgc ggtgtattct atgtatattc gccgccacct
    20821 catcctcaaa ggtatgacca agcccaataa actccaccaa gaggcgacca agtacgtgtc
    20881 agccaaggct caagctcgcc tgatttctct catgttggag gagcagatcc taacggaaaa
    20941 agaagaagaa atctacaaac gtggccgcaa taccaatagt cacacaaagg ctaaaaatgc
    21001 agatgtcgtg acttatcgta tgtccacggg atttgaagca gttatgggct atctccatat
    21061 gactgagaat ctggaacgtc ttgagagttt ggtttcatgg tgcatccaaa aagtggaggg
    21121 ctagaacatg agggcaaaag aactacaaga ctggtttcct gaggctcgga tttcagacca
    21181 accagtagag aaagagggct atctcacgct tcctttagct tctcagcagt ggattttgct
    21241 ggaggaagct gggctcagcg agcgtgaaaa gcagttggtt gcccttttga cccagcagga
    21301 gcaggctcgt tcgctaaacc cttggtattc ctatctggtt gaaggcaagg gacaggcacc
    21361 gcaagttttt aaaaagattc agttggttta ttgccatctt tcttattttc agcaggaaaa
    21421 tctggcttct tggctagata tgatgcggac tctttttccg aattgtcaga cagtgttaca
    21481 ggtcggagct caggattatg ttttcgtgct tcaacaagac aaatacactt ctgtaagaga
    21541 tattttaagt gatatgattg aagcagttga gtatgacttt ggacttcgtc tttctatcat
    21601 gttgggtcag gtttggtctc agacaggaca tcaagcccta tcagacttaa tcaaagctga
    21661 gcgggatttg ttcaagacat ggtggcgtca gggtcaccaa ggtgttcata ctttttctca
    21721 gctctatctt tggagtatgg gagaaagact cgtggacttg aagccaatta aagaatgtct
    21781 acaccagatg attttggatc aagatcagat tcaggaaatc attctctctc tttgggaaaa
    21841 tagtgctgtt ctcactaaaa cagcccagca actctatctg caccgcaatt ctctccaata
    21901 caagattgat aaatgggaag agttgacagg gcttcagttg aaagagttga ccgacctgac
    21961 cttgtgttat caattgattt taggttcttt gtcaactata gttggtttgt aaagaag
//
LOCUS       DAVBEO010000037        21414 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 009
            SAMEA1678075-rid20185393.denovo.037, whole genome shotgun sequence.
ACCESSION   DAVBEO010000037 DAVBEO010000000
VERSION     DAVBEO010000037.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678075
            Sequence Read Archive: ERR226392
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 21414)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21414)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980207.1
            Genome Coverage       :: 150x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:50:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 72 of 147
            Pseudo Genes (incomplete)         :: 72 of 147
            Pseudo Genes (internal stop)      :: 42 of 147
            Pseudo Genes (multiple problems)  :: 32 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21414
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678075-rid20185393.denovo.037"
                     /strain="KS 009"
                     /db_xref="taxon:1313"
     gene            66..287
                     /locus_tag="VQ543_001430"
     CDS             66..287
                     /locus_tag="VQ543_001430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000285460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET2612142.1"
                     /translation="MYRRLRDLREDHDLTQKQIAKILSFTNSAYAKIERGEHTLTADV
                     LVTLSNFYDVSTDYLLELTDFPDKIRFRK"
     gene            804..1043
                     /locus_tag="VQ543_001431"
                     /pseudo
     CDS             804..1043
                     /locus_tag="VQ543_001431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558195.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            1187..2416
                     /locus_tag="VQ543_001432"
     CDS             1187..2416
                     /locus_tag="VQ543_001432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HET2612143.1"
                     /translation="MKISKRHLLNYSILIPYLLLSILGLIVVYSTTSAILIEEGKSAL
                     QLVRNQGIFWIVSLILIALIYKLRLDFLRNERLIILVILIEMLLLFLARFIGISVNGA
                     YGWISVAGVTIQPAEYLKIIIIWYLAHRFSKQQEEIATYDFQVLTQNQWLPRAFNDWR
                     FVLLVLIGSLGIFPDLGNATILVLVSLIMYTVSGIAYRWFSTILALVSAASVFVLTTI
                     SLIGVETFSKIPVFGYVAKRFSAFFNPFADRADAGHQLANSYFAMVNGGWFGLGLGNS
                     IEKRGYLPEAHTDFVFSIVIEEFGFVGASLILALLFFMILRIILVGIRAENPFNAMVA
                     LGVGGMMLVQVFVNIGGISGLIPSTGVTFPFLSQGGNSLLVLSVAVAFVLNIDASEKR
                     AKLYRELENQPMNLLLK"
     gene            2436..5132
                     /gene="ppc"
                     /locus_tag="VQ543_001433"
     CDS             2436..5132
                     /gene="ppc"
                     /locus_tag="VQ543_001433"
                     /EC_number="4.1.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate carboxylase"
                     /protein_id="HET2612144.1"
                     /translation="MSLQKLENSSNKSVVQEEVLILTELLEDITKNMLAPETFEKIIQ
                     LKELSTQEDYQGLNRLVTSLSNDEMVYISRYFSILPLLINISEDVDLAYEINHQNNID
                     QDYLGKLSTTIKLVAEKENAVEILEHLNVVPVLTAHPTQVQRKSMLDLTNHIHSLLRK
                     YRDVKLGLINKDKWYNDLRRYIEIIMQTDMIREKKLKVTNEITNAMEYYNSSFLKAVP
                     HLTTEYKRLAQAHGLNLKQAKPITMGMWIGGDRDGNPFVTAKTLKQSALTQCEVIMNY
                     YDKKIYQLYREFSLSTSIVNVSKQVREMARQSKDNSIYREKELYRRALFDIQSKIQAT
                     KTYLIEDEEVGTRYETANDFYKDLIAIRDSLLENKGESLISGDFVELLQAVEIFGFYL
                     ASIDMRQDSSVYEACVAELLKSAGIHSRYSELSEEEKCDLLLKELEEDPRILSATHAE
                     KSELLAKELAIFKTARVLKDKLGDDVIRQTIISHATNLSDMLELAILLKEVGLVDTER
                     ARVQIVPLFETIEDLDHSEETMRKYLSLSLAKKWIDSRNNYQEIMLGYSDSNKDGGYL
                     SSCWTLYKAQQQLTAIGDEFGVKVTFFHGRGGTVGRGGGPTYEAITSQPLKSIKDRIR
                     LTEQGEVIGNKYGNKDAAYYNLEMLVSAAINRMITQKKSDTNTPNRYEAIMDQVVDRS
                     YDIYRDLVFGNEHFYDYFFESSPIKAISSFNIGSRPAARKTITEIGGLRAIPWVFSWS
                     QSRVMFPGWYGVGSSFKEFINKNPENIAILRDMYQNWPFFQSLLSNVDMVLSKSNMNI
                     AFEYAKLCEDEQVKAIYEIILNEWQVTKNVILAIEGHDELLADNPYLKASLDYRMPYF
                     NILNYIQLELIKRQRRGELSSDQERLIHITINGIATGLRNSG"
     misc_binding    5215..5432
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            5545..6549
                     /locus_tag="VQ543_001434"
     CDS             5545..6549
                     /locus_tag="VQ543_001434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HET2612145.1"
                     /translation="MKNKRLIGIIAALAVLVAGSLIYSSMNKSEAQNNKDEKKITKIG
                     VLQFVSHPSLDLIYKGIQDGLAEEGYKDDQVKIDFMNSEGDQSKVATMSKQLVANGND
                     LVVGIATPAAQGLASATKDLPVIMAAITDPIGANLVKDLKKPGGNVTGVSDHNPAQQQ
                     IELIKALTPNVKTIGALYSSSEDNSKTQVEEFKAYAEKAGLTVETFAVPSTNEIASTV
                     TVMTIKVDAIWVPIDNTIASGFPTVVSSNQSSKKPIYPSATAMVEVGGLASVVIDQHD
                     LGVATGKMIVQVLKGAKPADTPVNVFSTGKSVINKKIAQELGITIPESVLKEAGQVIE
                     "
     gene            6618..7484
                     /locus_tag="VQ543_001435"
     CDS             6618..7484
                     /locus_tag="VQ543_001435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET2612146.1"
                     /translation="MIVSIISQGFVWAILGLGIFMTFRILNFPDMTTEGSFPLGGAVA
                     VTLITKGVNPFLATLVAVGAGCLAGMAAGLLYTKGKIPTLLSGILVMTSCHSIMLLIM
                     GRANLGLLGTKQIQDVLPFDSDLNQLLTGLIFVSIVIALMLFFLDTKLGQAYIATGDN
                     PDMARSFGIHTGRMELMGLVLSNGVIALAGALIAQQEGYADVSRGIGVIVVGLASLII
                     GEVIFKSLSLAERLVTIVVGSIAYQFLVWAVIALGFNTSYLRLYSALILAVCLMIPTF
                     KQTILKGAKLSK"
     gene            7481..8239
                     /locus_tag="VQ543_001436"
     CDS             7481..8239
                     /locus_tag="VQ543_001436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000125420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2612147.1"
                     /translation="MTAIVELKNATKIVKNGFDEEKIILNDVSLEIFERDFITILGGN
                     GAGKSTLFNTIAGTLSLTSGTIRILGEDLTKFSPEKRAKYLSRVFQDPKMGTAPRMTV
                     AENLLIAKFRGEKRGLLPRRLTSYKDEFQATIEKVGNGLEKHLNTPIEFLSGGQRQAL
                     SLLMATLKRPELLLLDEHTAALDPKTSVALMELTDEFVKKDQLTALMITHHMEDALKY
                     GNRLIVMKEGRIIQDLNQEEKAKMKISDYYQLFE"
     gene            8329..10089
                     /gene="dnaG"
                     /locus_tag="VQ543_001437"
     CDS             8329..10089
                     /gene="dnaG"
                     /locus_tag="VQ543_001437"
                     /EC_number="2.7.7.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000227865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HET2612148.1"
                     /translation="MVDKQVIEEIKNNANIVEVIGDVISLQKAGRNYLGLCPFHGEKT
                     PSFNVVEDKQFYHCFGCGRSGDVFKFIEEYQGVTFMEAVQILGQRVGIEVEKPLYSEQ
                     KPASPHQALYDMHEDAAKFYHAILMTTTMGEEARNYLYQRGLTDEVLKHFWIGLAPPE
                     RNYLYQRLSDQYREEDLLDSGLFYLSDANQFVDTFHNRIMFPLTNDQGKVIAFSGRIW
                     QKTDSQTSKYKNSRSTAIFNKSYELYHMDRAKKSSGKTSEIYLMEGFMDVIAAYRAGI
                     ENAVASMGTALSREHVEHLKRLTKKLVLVYDGDKAGQAAILKALDEIGDMPVQIVSMP
                     DNLDPDEYLQKNGPEDLAYLLTKTRISPIEFYIHQYKPENSENLQAQIEFIEKIAPLI
                     VQEKSIAAQNSYIHILADSLASFDYTQIEQIVNESRQVQRQNRMERISRPTPITMPVT
                     KQLSAIMRAEAHLLYRMMESPLVLNDYRLREDFAFATPEFQVLYDLLGQYGNLPPEVL
                     AEQTEEVERAWYQVLAQDLPAEISPQELSEVEMTRNKALLNQDNMRIKKKVQEASHVG
                     DTDTALEELERLISQKRRME"
     gene            10092..11201
                     /gene="rpoD"
                     /locus_tag="VQ543_001438"
     CDS             10092..11201
                     /gene="rpoD"
                     /locus_tag="VQ543_001438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoD"
                     /protein_id="HET2612149.1"
                     /translation="MATKQKEVTTFDVQVAEFIRNHKQKGTATDDEINASLVIPFTLD
                     ADGIEDLLQRIQDAGISITDNEGNPSARVLSNEEEPELSDEDLIGSTSAKVNDPVRMY
                     LKEIGVVPLLTNEEEKELALAVEAGDIEAKQRLAEANLRLVVSIAKRYVGRGMQFLDL
                     IQEGNMGLMKAVDKFDYSKGFKFSTYATWWIRQAITRAIADQARTIRIPVHMVETINK
                     LVREQRNLLQELGQDPTPEQIAERMDMTPDKVREILKIAQEPVSLETPIGEEDDSHLG
                     DFIEDEVIENPVDYTTRIVLREQLDEILDTLTDREENVLRLRFGLDDGKMRTLEDVGK
                     VFNVTRERIRQIEAKALRKLRQPSRSKPLRDFIED"
     gene            11215..11544
                     /locus_tag="VQ543_001439"
     CDS             11215..11544
                     /locus_tag="VQ543_001439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HET2612150.1"
                     /translation="MAYTEEQIENIKTRILTALEEVIDPELGIDIVNLGLIYEIRFDG
                     DTGQTEIDMTLTTMGCPLADLLTDQIYDAMIEVPEVTDTEVKLVWYPAWTVEKMSRYA
                     RIALGIK"
     gene            11659..12702
                     /gene="cpoA"
                     /locus_tag="VQ543_001440"
     CDS             11659..12702
                     /gene="cpoA"
                     /locus_tag="VQ543_001440"
                     /EC_number="2.4.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosylglucosyldiacylglycerol synthase"
                     /protein_id="HET2612151.1"
                     /translation="MEKKKLRINMLSSSEKVAGQGVSGAYRELVRLLHRAAKDQLIVT
                     ENLPIEADVTHFHTIDFPYYLSTFQKKRSGRKIGYVHFLPATLEGSLKIPFFLKGIVK
                     RYVFSFYNRMEHLVVVNPMFIEDLVAAGIPREKVTYIPNFVNKEKWHPLPQEEVVRLR
                     TDLGLSDNQFIVVGAGQVQKRKGIDDFIRLAEELPQITFIWAGGFSFGGMTDGYEHYK
                     KIMENPPKNLIFPGIVSPERMRELYALADLFLLPSYNELFPMTILEAASCEAPIMLRD
                     LDLYKVILEGNYRATAGREEMKEAILEYQANPAVLKDLKEKAKNISREYSEEHLLQIW
                     LDFYEKQAALGRK"
     gene            12718..14043
                     /locus_tag="VQ543_001441"
     CDS             12718..14043
                     /locus_tag="VQ543_001441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HET2612152.1"
                     /translation="MRIGLFTDTYFPQVSGVATSIRTLKTELEKQGHAVFIFTTTDKD
                     VNRYEDWQIIRIPSVPFFAFKDRRFAYRGFSKALEIAKQYQLDIIHTQTEFSLGLLGI
                     WIARELKIPVIHTYHTQYEDYVHYIAKGILIRPSMVKYLVRGFLHDVDGVICPSEIVR
                     DLLSDYKVKVEKRVIPTGIELAKFERPEIKQENLKELRSKLGIQDGEKTLLSLSRISY
                     EKNIQAVLAAFADVLKEEDKVKLVVAGDGPYLNDLKEQAQNLEIQDSVIFTGMIAPSE
                     TALYYKAADFFISASTSETQGLTYLESLASGTPVIAHGNPYLNNLISDKMFGALYYGE
                     HDLAGAILEALIATPDMNEHTLSEKLYEISAENFGKRVHEFYLDAIISNNFQKDLAKD
                     DTVSQRIFRTVLYLPQQVVAVPVKGSRRMLKASKTQLISMRDYWKDHEE"
     gene            14074..14250
                     /locus_tag="VQ543_001442"
     CDS             14074..14250
                     /locus_tag="VQ543_001442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HET2612153.1"
                     /translation="MRSGRDKKIAGVCAGVAHYLDMDPTIVQVIWGVLTCCYGAGIVA
                     YIILWIIAPVATDY"
     gene            14309..14443
                     /locus_tag="VQ543_001443"
     CDS             14309..14443
                     /locus_tag="VQ543_001443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4044 domain-containing protein"
                     /protein_id="HET2612154.1"
                     /translation="MAFGDNGNRKKTMFEKITLFIVIIMLVASLLGIFATAIGALSNL
                     "
     gene            14507..15817
                     /gene="obgE"
                     /locus_tag="VQ543_001444"
     CDS             14507..15817
                     /gene="obgE"
                     /locus_tag="VQ543_001444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000061643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase ObgE"
                     /protein_id="HET2612155.1"
                     /translation="MSMFLDTAKIKVKAGNGGDGMVAFRREKYVPNGGPWGGDGGRGG
                     NVVFVVDEGLRTLMDFRYNRHFKADSGEKGMTKGMHGRGAEDLRVRVPQGTTVRDAET
                     GKVLTDLIEHGQEFIVAHGGRGGRGNIRFATPKNPAPEISENGEPGQERELQLELKIL
                     ADVGLVGFPSVGKSTLLSVITSAKPKIGAYHFTTIVPNLGMVRTQSGESFAVADLPGL
                     IEGASQGVGLGTQFLRHIERTRVILHIIDMSASEGRDPYEDYLAINKELESYNLRLME
                     RPQIIVANKMDMPESQENLEEFKKKLSENYDEFEELPAIFPISGLTKQGLATLLDATA
                     ELLDKTPEFLLYDESDMEEEAYYGFDEEEKAFEISRDDDATWVLSGEKLMKLFNMTNF
                     DRDESVMKFARQLRGMGVDEALRARGAKDGDLVRIGKFEFEFVD"
     gene            15827..15985
                     /locus_tag="VQ543_001445"
     CDS             15827..15985
                     /locus_tag="VQ543_001445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2612156.1"
                     /translation="MGDKPISFRDADGNFVSAADVWNEKKLEELFNRLNPNRALRLAR
                     TKKENPSQ"
     gene            17035..18294
                     /locus_tag="VQ543_001446"
     CDS             17035..18294
                     /locus_tag="VQ543_001446"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HET2612157.1"
                     /translation="MRKIVINGGLPLQGEITISGAKNSVVALIPAIILADDVVTLDCV
                     PDISDVASLVEIMELMGATVKRYDDVLEIDPRGVQNIPMPYGKINSLRASYYFYGSLL
                     GRFGEATVGLPGGCDLGPRPIDLHLKAFEAMGATASYEGDNMKLSAKDTGLHGASIYM
                     DTVSVGATINTMIAAVKANGRTIIENAAREPEIIDVATLLNNMGAHIRGAGTNIIIID
                     GVERLHGTRHQVIPDRIEAGTYISLAAAVGKGIRINNVLYEHLEGFIAKLEEMGVRMT
                     VSEDSIFVEEQSNLKAINIKTAPYPGFATDLQQPLTPLLLRANGRGTIVDTIYEKRVN
                     HVFELAKMDADISTTNGHILYTGGRDLRGASVKATDLRAGAALVIAGLMAEGKTEITN
                     IEFILRGYSDIIEKLRNLGADIRLVED"
     gene            18310..18861
                     /locus_tag="VQ543_001447"
     CDS             18310..18861
                     /locus_tag="VQ543_001447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET2612158.1"
                     /translation="MNIWTKLAMFSFFETDRLYLRPFFFSDSQDFREIASNPENLQFI
                     FPTQASLEESQYALANYFMKSPLGVWAICDQKNQQMIGSIKFEKLDEIKKEAELGYFL
                     RKDAWSQGFMTEVVRKICQLSFEEFGLKQLFIITHLENEASQRVALKSGFSLFRQFKG
                     SDRYTRKMRDYLEFRYVKGEFNE"
     gene            18854..20131
                     /locus_tag="VQ543_001448"
     CDS             18854..20131
                     /locus_tag="VQ543_001448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HET2612159.1"
                     /translation="MSKHQEILSYLEELPVGKRVSVRSISNHLGVSDGTAYRAIKEAE
                     NRGIVETRPRSGTIRVKSQKVAIDRLTFAEIAEVTSSEVLAGQEGLEREFSKFSIGAM
                     TEQNILSYLHDGGLLIVGDRTRIQLLALENENAVLVTGGFQVHDDVLKLANQKGIPVL
                     RSKHDTFTVATMINKALSNVQIKTDILTVEKLYRPSHEYGFLRETDTVKDYLDLVRKN
                     RSSRFPVINQHQVVVGVVTMRDAGDKSPSTTIDKVMSRSLFLVGLSTNIANVSQRMIA
                     EDFEMVPVVRSNQTLLGVVTRRDVMEKMSRSQVSALPTFSEQIGQKLSYHHDEVVITV
                     EPFMLEKNGVLANGVLAEILTHMTQDLVVNSGRNLIIEQMLIYFLQAVQIDDILRIQA
                     RIIHHTRRSAIIDYDIYHGHQIVSKANVTVKIN"
     gene            20147..21007
                     /locus_tag="VQ543_001449"
     CDS             20147..21007
                     /locus_tag="VQ543_001449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013903404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl aminopeptidase"
                     /protein_id="HET2612160.1"
                     /translation="MITLKSAREIEAMDKAGDFLASIHIGLRDLIKPGVDMWEVEEYV
                     RRRCKEENFLPLQIGVDGAMMDYPYATCCSLNDEVAHAFPRHYILKDGDLLKVDMVLG
                     GPIAKSDLNVSKLNFNNVEQMKKYTQSYSGGLADSCWAYAVGTPSEEVKNLMDVTKEA
                     MYKGIEQAVVGNRIGDIGAAIQEYAESRGYGVVRDLVGHGVGPTMHEEPMVPNYGIAG
                     RGLRLREGMVLTIEPMINTGDWEIDTDMKTGWAHKTIDGGLSCQYEHQFVITKDGPVI
                     LTSQGEEGTY"
     gene            21230..21340
                     /locus_tag="VQ543_001450"
                     /pseudo
     CDS             21230..21340
                     /locus_tag="VQ543_001450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818216.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase"
BASE COUNT         6551 a         3678 c         4805 g         6380 t
ORIGIN      
        1 ccagttagga cactttgaat gatttcttag ttttatatat tatacttttc tcaggagaaa
       61 gctagatgta cagacgtttg agagatttga gggaagatca cgatttgacc caaaaacaaa
      121 tagctaaaat actttcgttt acaaactcag cttatgctaa aattgaacgg ggtgagcata
      181 cgttaacagc agatgtattg gtaactctct caaactttta cgatgtcagt acagactacc
      241 tattggaatt gacagatttt cctgataaaa ttcgctttag aaaataatct cctcaatttc
      301 atagagtgtg aaaatgagga gattttttat ttgttctttg aaaattaaat agtccaaaat
      361 ggtactttcc tcatttgtgg agcaaatttg aatggctcgc catgataaga gcgattttaa
      421 agccatcaat aaaatagagc gatactttat atgccatgat acaaatgata tacaatgata
      481 cttctgaccg ttcaggctgc catcgtaaaa gagcagcaag tgaaattctt atgatgactt
      541 catcagtcat gccacgttga atgtgtgagt ttgttagaga aacgcaatta atcctcaaaa
      601 ggttccccga accttttgag ttccacagac gcatcacgtg gagtgtgtaa gcttgttgct
      661 aaaagcgtaa aaaccttgga acgaaaggaa taatagactt cctgcgaaac aaaaatacaa
      721 tacaataaaa ctatggatga tgaagcaagt aaacaattaa gcgatagccg tttcaagagc
      781 cttgtaggtg ttcagcgcac gagatgttag ctgtgttaaa aacagcttat caacgcaacg
      841 taaacgcgca aaaggtggac gaaaaaccaa attaagccta gacgatctcc tcatggtaac
      901 tattcaatac atgcgagaat agcgcactta tgaacaaatt gcggctgatt ttggcattca
      961 cgaaagcaac ataattagtc ggaggtcaat ggattgaagc aactcttatt caaaatggtt
     1021 ttacgatttc aaattctgcc ttaattctgt aaaaacagta aaattcgaag gattgtaagg
     1081 taagagtttt tttctttctg aaaaaatggt ataatagcaa tcaaaactag aaaataaaac
     1141 ggaatttgga acagatttgt ctgtatccta gtagagtggt gatactatga agattagtaa
     1201 gaggcactta ttaaattatt ccatcttgat tccctacttg cttttatcta ttttgggctt
     1261 gattgtggtc tattcgacca ccagtgctat tttaattgaa gaaggcaaga gcgccttgca
     1321 gttggttcga aaccaaggaa tcttttggat tgttagtttg atactgattg ccttaattta
     1381 taaattgaga ctagattttt tgagaaatga gcgactaatc attttagtta tattaataga
     1441 aatgctttta ttgttcttgg ctcgttttat tggtatttca gtaaacgggg catacggttg
     1501 gatttcggtt gcaggagtaa ctattcagcc agctgagtac ttaaaaatca ttattatttg
     1561 gtatttagct caccgattct ccaaacagca agaagaaata gctacttatg attttcaagt
     1621 tttgactcaa aatcaatggc ttccccgtgc ttttaatgat tggcgattcg ttctcctagt
     1681 tctgattgga agtttgggaa ttttccctga tttaggaaat gcgactattt tagtcttggt
     1741 ttccttgatt atgtatacag ttagtggaat cgcttatcgc tggttttcaa ccattctggc
     1801 gctcgtatct gccgcttctg tctttgtctt gaccactatc agcctaatcg gtgttgagac
     1861 cttttcaaaa attccagtat ttggctatgt agccaaacgc tttagtgcct tttttaatcc
     1921 ttttgccgat cgtgctgatg caggtcacca gttagctaat tcttattttg ccatggtcaa
     1981 tggtggttgg tttggtctag gtcttggaaa ctcgattgaa aaacgaggtt atttgccaga
     2041 agctcataca gactttgtct tttctatcgt gattgaagaa tttggctttg ttggtgccag
     2101 tcttatttta gctctcttgt ttttcatgat tttgcggatt atcttggtcg gtattcgagc
     2161 ggagaatcct ttcaatgcca tggttgcact cggtgtcgga gggatgatgt tggttcaggt
     2221 atttgtcaat atcggaggga tttcgggctt gattccatct acaggagtaa ccttcccctt
     2281 cttatcccag ggtggaaata gtcttctagt cttatcagtg gcagtagcct ttgtcttaaa
     2341 tattgatgcc agtgaaaaac gcgctaagtt gtaccgagaa ttggaaaatc aaccaatgaa
     2401 ccttctgttg aagtaggata aagaaaggat agtttatgtc tcttcaaaaa ttagaaaatt
     2461 ctagtaataa aagtgttgtg caagaagaag tcttgattct aacagaatta ctggaagata
     2521 ttactaaaaa tatgcttgcc ccagagacct ttgaaaaaat aatacagttg aaagaattat
     2581 caacgcagga agattatcaa ggtctaaacc gtctagtgac tagcttatca aatgatgaaa
     2641 tggtctatat ttcacgctat ttctctatct tgcctctttt gattaatatt tcagaggatg
     2701 tggatttagc ttatgaaatc aatcatcaaa ataatattga tcaggactat ttaggtaaat
     2761 tatctacaac gattaaattg gtagcagaaa aggaaaatgc cgttgagatc ctagaacact
     2821 tgaatgttgt tccggttttg acagcccatc caacacaagt gcaacgcaaa agtatgttgg
     2881 atttaacaaa tcatattcat agtcttttgc gtaaataccg tgatgttaag ttggggttga
     2941 tcaataaaga taaatggtac aatgatttgc gtcgttacat cgaaattatc atgcagacag
     3001 acatgattcg tgagaaaaaa ttaaaagtga ctaacgaaat cacgaatgct atggaatatt
     3061 ataacagctc ctttttgaaa gctgtacctc atttgacgac ggagtataag cgcttagcgc
     3121 aagcgcatgg tctgaattta aaacaggcta aaccaatcac catgggtatg tggataggtg
     3181 gtgaccgtga tggaaatcca tttgttacag caaagacctt gaagcagtct gcactcactc
     3241 aatgtgaagt catcatgaac tactatgata aaaagattta ccaactttat cgtgaatttt
     3301 ctctttcaac tagcattgtc aacgtcagca agcaagtcag agaaatggct cgtcaatcca
     3361 aggataactc gatttaccgc gaaaaagagc tttaccgtcg tgccttgttt gatattcaat
     3421 caaaaattca ggcaactaaa acctatctga ttgaggatga agaagttggg actcgttatg
     3481 aaaccgccaa tgatttctac aaggatttga ttgccattcg agattctcta ctagagaata
     3541 agggcgagtc cttgatttca ggtgattttg tggaattatt gcaggcagta gagatatttg
     3601 gtttttacct agcatcaatt gatatgcgac aagactctag cgtctatgaa gcctgtgtgg
     3661 cagaactctt gaaatcagca ggaattcatt ctcgttatag cgagttgagc gaagaagaaa
     3721 agtgtgacct tcttttgaaa gaattagaag aagatccccg aattctttct gcgactcacg
     3781 cagaaaaatc agaattatta gcaaaagaac tagctatttt taagacggct cgtgttttga
     3841 aagataagtt gggagatgat gtcatccgtc agaccatcat ttcacatgca accaaccttt
     3901 ctgatatgct agaattagct attctgttaa aagaagtagg actggtggat acggaaaggg
     3961 cgcgtgttca gattgttccc ctttttgaaa caattgaaga cttggatcat tcagaggaaa
     4021 caatgagaaa atatctttct cttagccttg ccaaaaaatg gattgactca cgaaataact
     4081 accaagaaat catgcttggc tactctgaca gtaataaaga tggcggttac ttgtcatcat
     4141 gttggaccct ctacaaggct caacaacaat tgactgctat tggagatgaa tttggcgtta
     4201 aggttacctt cttccatggt cgtggtggta ctgtcggtcg tggtggtggg ccaacctatg
     4261 aagccattac atctcaaccg ctcaagtcta tcaaggatcg tatccgtttg acggagcagg
     4321 gtgaagtaat tgggaataaa tacggtaaca aagacgccgc ttactataac cttgaaatgc
     4381 tagtatcggc agctattaac cgtatgatta ctcagaagaa gagcgatacc aataccccaa
     4441 atcgttatga agccattatg gatcaagtag tggaccgtag ttacgatatc taccgtgatt
     4501 tggtctttgg taatgagcat ttctatgatt atttcttcga gtcaagtcca atcaaggcta
     4561 tttcaagttt taatattggt tctcgtccag ccgctcgtaa gactattact gaaatcggtg
     4621 gtttgcgtgc catcccttgg gtattctcat ggtcacagag tcgtgttatg ttccctggat
     4681 ggtacggggt tggttcaagc ttcaaggaat ttatcaataa aaatccagag aatattgcta
     4741 tcttacgaga tatgtaccaa aattggcctt tcttccaatc gcttctttca aatgttgata
     4801 tggttttgtc aaaatcaaat atgaatattg cttttgaata tgctaaactt tgtgaagacg
     4861 agcaagttaa ggccatctat gagattattt taaatgaatg gcaagttact aagaacgtta
     4921 tcttggctat tgaaggacat gacgaactct tagctgacaa tccatatcta aaagctagtc
     4981 tggattaccg tatgccttac tttaatattc tcaactatat tcagttagag ttgattaaac
     5041 gccaacgtcg tggagaattg tccagtgatc aagaacgatt gattcatatc accatcaacg
     5101 gaattgcgac aggattgcgt aattcaggtt gataattttc aagagtgaat gctaaaagtg
     5161 aatatcaaaa aaattctaat agactattga caagtagttt aaaaatgata taatttaacc
     5221 attcagaaaa gtaatcatac aaacttttta gagagtctgt ggtagctgaa aacagataag
     5281 tggcgatgat gaaaattggg ctgaatgcta tttagaattt gaaattataa aaattcggta
     5341 agcacacctt acagtgcatc tcgttattgc gagactgagc gatagggaaa ttccctataa
     5401 ttgaggtggt accgcgcatc gacgtcctca cacaagtttt ttgtgtgagg atttttttga
     5461 tggaggttag tatggaaaga aaacgatggc gtcgcttgtt tagataagtg aaatatgtta
     5521 aaggaaataa aaaggagaaa cagaatgaaa aataaacgtt taattggaat tattgctgca
     5581 ttagcagtct tagtagcagg aagcttgatt tattcttcaa tgaataaatc agaagctcag
     5641 aataataagg atgagaagaa aataaccaag attggtgtgc ttcaatttgt gagccatcca
     5701 tcccttgatt tgatttataa agggatccaa gatggacttg cagaagaagg atataaagat
     5761 gatcaagtta aaattgattt tatgaactca gaaggtgatc aaagtaaggt tgcgacaatg
     5821 agtaaacaat tggttgcaaa tgggaatgac cttgtggttg gtattgcaac accagcagcc
     5881 caagggttgg ctagtgcaac aaaagaccta ccagttatca tggccgctat tacagaccca
     5941 attggtgcta acttggttaa agatttgaaa aaaccaggtg gtaacgttac aggggtatct
     6001 gaccacaatc cagctcaaca acaaattgaa ctcatcaagg ctctgacacc gaatgtgaaa
     6061 acaatcggag ctctttactc aagtagcgaa gacaattcaa aaacacaggt tgaagaattt
     6121 aaggcttatg ctgaaaaagc aggtctgaca gtggaaacat ttgcagttcc ttcaacaaat
     6181 gaaattgcct caactgtcac tgttatgact atcaaggtag atgctatttg ggttccaatt
     6241 gataacacca ttgcatcagg atttccaacg gttgtctcta gcaatcaaag ttctaagaaa
     6301 ccaatttatc ccagtgcgac agctatggta gaagtaggtg gtttggcatc agttgtaatt
     6361 gaccaacatg accttggtgt ggcaacaggt aaaatgattg tgcaagtctt gaaaggtgca
     6421 aaaccagccg ataccccagt caatgtcttt tcaactggta agtcagtcat caataaaaaa
     6481 atagcacaag aactaggtat tactattcct gagtctgttc tcaaagaagc aggacaagtc
     6541 atcgaataaa taaggtaggg aggaggagac tcttcccatt ttttaaaaag atgaatatag
     6601 aaaggattaa ataaaatatg attgtttcca ttatttctca aggatttgtc tgggctattc
     6661 taggtctggg aatctttatg acatttagga ttttaaactt tccagatatg acgacagaag
     6721 gttccttccc tcttggggga gctgttgctg tcactttgat aaccaaaggc gtgaacccat
     6781 ttttagcgac acttgttgct gtaggagcag gttgtttggc tggaatggca gcaggccttc
     6841 tttatacaaa agggaagatc ccaaccttgc tctcagggat tttggtgatg acttcttgtc
     6901 actcaatcat gctcttgatt atgggacgtg cgaatttagg cctgcttgga accaagcaaa
     6961 ttcaggatgt tttgcctttt gattcggatt tgaatcaact cttgacaggt ctcatctttg
     7021 tgagcattgt tattgctctc atgctctttt tcttggacac taaactcgga caagcctata
     7081 ttgctacagg ggataatcct gatatggcta gaagtttcgg gattcatact ggacgcatgg
     7141 agctcatggg cttggtctta tcaaatggtg tgattgccct tgcaggtgcc ctcattgctc
     7201 agcaagaagg ctatgccgat gtgtctcgag ggatcggggt tatcgttgtg gggcttgcaa
     7261 gtttgattat tggagaagtt attttcaaga gtttgagctt ggcagagcgt ttggttacta
     7321 tcgttgtagg ttctatcgct tatcaatttt tagtgtgggc agttatcgca cttggcttta
     7381 atacaagtta ccttcgttta tacagtgcct tgattttagc agtctgcctc atgattccaa
     7441 catttaagca aacaatcttg aaaggagcca agttaagcaa atgacagcaa ttgtagaatt
     7501 aaaaaatgca accaaaattg ttaaaaatgg ctttgatgaa gaaaagatta ttttaaatga
     7561 tgtttcctta gaaatttttg aacgggactt tatcacgatt ttgggcggaa atggtgctgg
     7621 aaaatcaacc ctctttaaca ctatagcagg gaccttatca ctaactagtg gaactatccg
     7681 tattttaggt gaagatctca ctaagttttc acccgagaag cgtgccaagt acctgtctcg
     7741 tgtcttccaa gatccaaaga tggggacagc tccccgtatg acggtcgctg aaaatctttt
     7801 aatcgccaag tttcgtggtg agaagcgtgg attgttacca cgacgcttga ctagctataa
     7861 ggatgaattt caggcaacca ttgaaaaagt aggaaatggt cttgagaaac acttgaatac
     7921 accgattgag ttcttatcag gtggacaaag acaggctttg agtctcttga tggcaacctt
     7981 gaagcgacct gaattactcc tgttagatga gcatactgct gccctggatc caaagactag
     8041 tgttgctttg atggaattga cagatgaatt tgttaagaaa gatcagctaa cagcccttat
     8101 gattactcat catatggaag atgctctcaa atacggcaat cgcttgattg tcatgaaaga
     8161 aggacggatt atccaagatt taaaccaaga agaaaaagca aaaatgaaaa tctctgatta
     8221 ttatcaactc tttgaataaa gtagggaaaa tgagtgaaat ggtttacttt ttttctgaaa
     8281 taaagtatac tatataaagt aaactatgat aacatggagg tattgtgtat ggttgacaaa
     8341 caagtcattg aagaaatcaa aaacaatgcc aacattgtgg aagtcatagg agatgtgatt
     8401 tctttacaaa aggcaggacg gaactatcta gggctctgtc cttttcatgg tgaaaaaaca
     8461 ccttctttca acgttgtaga ggacaagcag ttttaccact gttttggttg tggtcgctca
     8521 ggtgatgtct ttaaattcat cgaggagtac caaggggtta cctttatgga ggctgtccaa
     8581 atcttaggtc agcgtgtcgg gattgaggtt gaaaaaccgc tttatagtga acagaagcca
     8641 gcctcgcctc accaagctct ttatgatatg cacgaagatg cggctaaatt ttaccatgct
     8701 attctcatga caacgactat gggcgaagag gccagaaatt acctttatca gcggggtttg
     8761 acagatgaag tgcttaaaca tttttggatt ggtttagcac ctccagaacg aaactatctc
     8821 tatcaacgtt tgtctgatca gtatcgtgaa gaggatttac tggattcagg cctgttttat
     8881 ctctcggatg ccaatcaatt tgtagacacc tttcacaatc gcattatgtt tcccctgaca
     8941 aatgaccaag gaaaggtcat tgccttctca ggtcgtatct ggcaaaaaac ggattcacaa
     9001 acttctaagt ataaaaacag ccgatcgact gcaattttta acaaaagtta cgaattatat
     9061 catatggata gggcaaaaaa atcttctgga aaaactagtg agatttacct gatggaagga
     9121 ttcatggatg ttattgcagc ctatcgggct ggaatcgaaa atgctgtggc gtcgatggga
     9181 acggccttga gtcgagagca tgttgagcat ctgaaaaggt taaccaagaa attggttctt
     9241 gtttacgatg gagataaggc tgggcaagcc gcgatattga aagcattgga tgaaattggt
     9301 gatatgcctg tgcaaatcgt tagcatgcct gataacttgg atcctgatga gtatctacaa
     9361 aaaaatggtc cagaagactt ggcctatcta ttaacaaaaa ctcgtattag tccgattgag
     9421 ttctacattc atcagtacaa acctgaaaac agtgaaaatc tgcaggctca gattgagttt
     9481 attgaaaaaa tagctccctt gattgttcaa gaaaagtcca tcgctgctca aaacagctat
     9541 attcatattt tagctgacag tctggcgtcc tttgattata cccagattga gcagattgtt
     9601 aatgagagtc gtcaggtgca aaggcagaat cgcatggaaa gaatttccag accgacgcca
     9661 atcaccatgc ctgtcaccaa gcagttatcg gctattatga gggcagaagc ccatctactc
     9721 tatcggatga tggaatcccc tcttgttttg aacgattacc gtttgcgaga agactttgca
     9781 tttgctacac ctgaatttca ggtcttatat gacttgcttg gccagtatgg aaatcttcct
     9841 ccagaagttt tagcagagca gacagaggaa gttgaaagag cttggtacca agttttagct
     9901 caggatttgc ctgctgagat atcgccgcag gaacttagtg aagtagagat gactcgaaac
     9961 aaggctctct tgaatcagga caatatgaga atcaaaaaga aggtgcagga agctagccat
    10021 gtaggagata cagatacagc cctagaagaa ttggaacgtt taatttccca aaagagaaga
    10081 atggagtaat aatggcaaca aaacaaaaag aagtaacaac atttgacgta caggtagcag
    10141 aatttatccg taatcataag caaaaaggga cagcaacaga tgatgaaatc aatgcaagtc
    10201 tggttattcc ttttaccttg gacgctgatg ggattgaaga tctcttgcaa cggattcagg
    10261 atgcagggat ttctatcaca gataacgaag gaaatccaag tgcgcgtgtt cttagcaatg
    10321 aagaagaacc agaactcagc gatgaggact tgattggatc aacttctgct aaggtcaatg
    10381 accctgtccg tatgtacttg aaagaaatag gggtcgttcc tctcttgacc aatgaagagg
    10441 agaaagagtt ggcactggct gttgaagctg gcgatatcga agccaaacaa cgtcttgcgg
    10501 aagccaatct tcgtttggtt gtttccattg ccaaacgcta tgtcggtcgt ggcatgcagt
    10561 tccttgactt gattcaagaa ggaaatatgg gcttgatgaa ggcggttgac aagtttgact
    10621 attctaaagg gttcaagttt tcaacttatg caacttggtg gattcgtcag gctatcactc
    10681 gtgctattgc ggaccaagct cgtaccatcc gtatcccagt tcacatggtt gaaactatca
    10741 ataaattggt tcgtgaacag cggaatctcc ttcaagaatt ggggcaagat ccgacaccag
    10801 aacagattgc tgaacgaatg gatatgacac ctgataaggt tcgtgaaatc ttgaagattg
    10861 cccaagaacc agtatctctt gaaactccta tcggtgaaga ggacgatagc caccttggag
    10921 actttatcga agatgaagtg attgaaaatc cagtggatta tacgactcgt atcgtcttgc
    10981 gtgagcaatt ggatgaaatc ttagatactc ttacagaccg tgaagaaaat gttctgcgtc
    11041 tacgttttgg actagatgat ggaaaaatgc gcacacttga agatgtgggg aaagtcttta
    11101 acgtaactcg tgagcgtatc cgtcagattg aagcaaaggc tttgagaaaa ctacgccaac
    11161 caagtcgcag caaaccgctt cgtgatttta ttgaagacta agagtgagga aaatatggct
    11221 tatacagaag agcaaattga aaacatcaaa acacggattt taacagcctt ggaagaagtc
    11281 atcgaccctg agttgggaat cgatattgtc aatcttggtt tgatctatga gattcgtttt
    11341 gacggtgaca cagggcaaac agagattgac atgactttga caactatggg ttgtccctta
    11401 gcagaccttt tgacagacca gatttatgat gctatgatag aggttccaga agtaacggat
    11461 actgaggtta aattagtctg gtatccagcc tggacagttg aaaaaatgag tcgctatgcc
    11521 cgcattgccc taggcattaa gtaaacatat aaaagcatgt gagagactag aggaaaagcg
    11581 aggaaatttc ccctcttttc ctctagtctc tcctttcttt tgctgatttt attcaaagaa
    11641 aatgatataa tagtagttat ggagaaaaag aaattacgca tcaatatgtt gagttcaagt
    11701 gagaaagtag caggacaggg agtttcaggt gcttaccgtg aattagttcg tcttcttcac
    11761 cgtgctgcca aggaccaatt gattgttaca gaaaatcttc caatcgaggc agatgtgact
    11821 cactttcata cgattgattt tccctattat ttatcaacct tccaaaagaa acgctcaggg
    11881 agaaagattg gctatgtgca tttcttgcca gctacacttg aaggaagttt gaaaattcca
    11941 tttttcttaa agggaattgt gaaacgctat gtattttctt tttacaaccg gatggagcac
    12001 ttggttgtgg tcaatcctat gtttattgag gatttggtag cagctggtat tccacgtgaa
    12061 aaagtgacct atattcctaa ctttgtcaac aaggaaaaat ggcatcctct accacaagaa
    12121 gaggtagtca gactgcgcac agatcttggt cttagtgaca atcagtttat cgtagtaggt
    12181 gctgggcaag ttcagaaacg taaagggatt gatgacttta tccgtctggc tgaggaattg
    12241 cctcagatta cctttatctg ggctggtggc ttctcttttg gtggtatgac agatggttat
    12301 gaacactata agaaaattat ggaaaatccc cctaaaaatt tgatttttcc aggcattgta
    12361 tcgccagagc ggatgcgcga attgtatgct ctagcggatc ttttcttgtt gcctagttac
    12421 aatgagctct ttcctatgac tattttagaa gctgcgagtt gtgaggctcc tattatgttg
    12481 cgtgatttag atctctataa ggtgattttg gagggaaatt atcgggcgac agcgggtaga
    12541 gaagagatga aagaggctat tttggaatat caagcaaatc ctgctgtctt aaaagatctc
    12601 aaagaaaagg ctaagaatat ttccagagag tattctgaag agcatctgtt acaaatctgg
    12661 ttggactttt atgagaaaca agccgcttta gggagaaagt aaaaagtgag gtaatctatg
    12721 cgaattggtt tatttacaga tacctatttt cctcaggttt ctggtgttgc gaccagtatt
    12781 cgaaccttga aaacagaact tgaaaagcag ggacatgctg tttttatctt tacgacgaca
    12841 gataaggatg tcaatcgcta cgaagattgg caaattatcc gcattccaag tgttcctttc
    12901 tttgctttta aggatcgtcg ctttgcctac cgaggtttta gcaaggcact tgaaattgct
    12961 aaacagtatc agctagatat tatccatact cagacagaat tttctcttgg cctgttgggg
    13021 atttggattg cgcgtgaatt gaaaattcca gtcatccata cctatcacac ccagtatgaa
    13081 gactatgtcc attatattgc taaggggata ttgatccggc cgagtatggt caagtatctg
    13141 gttagaggtt tcctgcatga tgtggatggg gttatttgcc ctagtgagat tgtccgtgac
    13201 ttgctatctg attataaggt caaggttgaa aaacgggtca ttcctactgg gattgaatta
    13261 gccaagtttg agcgtccgga aatcaagcag gaaaatttga aagaactgcg tagtaaacta
    13321 gggattcaag atggtgaaaa gacgttgctt agtctttcga gaatctccta tgaaaaaaat
    13381 attcaagcag ttttagcagc ctttgctgat gttctgaaag aggaagacaa ggttaaactg
    13441 gtagtagctg gggatggccc ttatctgaat gacctcaaag agcaagccca gaacctagag
    13501 attcaagact cagtcatctt tacagggatg attgctccta gtgagacggc tctttactat
    13561 aaagcggcgg atttcttcat ttcggcatcg acaagcgaaa cgcaaggttt gacctacttg
    13621 gaaagcttag ccagtggaac acctgtcatt gctcacggaa atccttattt gaacaacctc
    13681 atcagtgata aaatgtttgg agccttgtac tatggagaac atgatttggc tggtgctatt
    13741 ttggaagccc tgattgcaac accagacatg aatgagcata ccttatcaga gaaattgtat
    13801 gagatttcag ctgagaactt tgggaaacga gtgcatgagt tttatctgga tgccattatt
    13861 tcaaataact tccagaaaga tttggctaaa gatgatacgg tcagtcagcg tatctttagg
    13921 acagttttgt atcttccgca acaggtggtt gctgtacctg taaaaggatc tagacgcatg
    13981 ttgaaggctt caaaaacaca gttgatcagt atgagagact attggaaaga ccatgaagaa
    14041 tagaaagagg aacagctatg aaaaaaacaa ttaatgagaa gcggtcgtga taaaaagatt
    14101 gcgggtgttt gtgctggggt ggcccattat ctggatatgg atccgactat cgttcaagtc
    14161 atttggggtg ttcttacttg ctgttacgga gctggaattg tagcttacat tattttatgg
    14221 attatcgcac cagtagcaac tgactattga aaactagctc aattcatgct aagataatag
    14281 aaaatagaat gtaacgaagg agagaaaaat ggcatttgga gataatggaa atcgtaaaaa
    14341 aactatgttt gagaaaataa ccttgtttat cgtgattatc atgctagtag caagtttatt
    14401 gggaattttt gcaactgcaa ttggtgccct cagtaatcta taaaatagat tcaagaaaat
    14461 ttagtgactg ggatttccca gccctttttt aaagtgagaa gaaataatga gtatgttttt
    14521 agatacagct aagattaagg tcaaggctgg taatggtggc gatggtatgg ttgcctttcg
    14581 tcgtgaaaaa tatgtcccta atggaggccc ttggggtggt gatggtggtc gtggaggcaa
    14641 tgtggtcttc gttgtagacg aaggactacg taccttgatg gatttccgct acaatcgtca
    14701 tttcaaggct gattctggtg aaaaagggat gaccaaaggg atgcatggtc gtggtgctga
    14761 ggaccttaga gttcgagtac cacaaggtac gactgttcgt gatgcggaga ctggcaaggt
    14821 tttaacagat ttgattgaac atgggcaaga atttatcgtt gcccacggtg gtcgtggtgg
    14881 acgtggaaat attcgtttcg cgacaccaaa aaatcctgca ccggaaatct ctgaaaatgg
    14941 agaaccaggt caggaacgtg agttacaatt ggaactaaaa atcttggcag atgtcggttt
    15001 agtaggattc ccatctgtag ggaagtcaac acttttaagt gttattacct cagctaagcc
    15061 taaaattggt gcctaccact ttaccactat tgtaccaaat ttaggtatgg ttcgcaccca
    15121 atcaggtgaa tcctttgcag tagccgactt gccaggtttg attgaagggg ctagtcaagg
    15181 tgttggtttg ggaactcagt ttctccgtca catcgagcgt acacgtgtta tccttcacat
    15241 cattgatatg tcagctagcg aaggccgtga tccatatgag gattacctag ctatcaataa
    15301 agagctggag tcttacaatc ttcgcctcat ggagcgtcca cagattattg tagctaataa
    15361 gatggacatg cctgagagtc aggaaaatct tgaagaattt aagaaaaaat tgtctgaaaa
    15421 ttatgatgaa tttgaagagt taccagctat cttcccaatt tctggattga ccaagcaagg
    15481 tctggcaaca cttttagatg ctacagctga attgttagac aagacaccag aatttttgct
    15541 ctacgacgag tccgatatgg aagaagaagc ttactatgga tttgacgaag aagaaaaagc
    15601 ctttgaaatt agtcgtgatg acgatgcgac atgggtactt tctggtgaaa aactcatgaa
    15661 actctttaat atgaccaact ttgatcgtga tgaatctgtc atgaaatttg cccgtcagct
    15721 tcgtggtatg ggggttgatg aagcccttcg tgcgcgtgga gctaaagatg gggatttggt
    15781 ccgcattggt aaatttgagt ttgaatttgt agactaggag actggtatgg gagataaacc
    15841 gatatctttc cgagatgcgg atggtaattt tgtttccgcc gcagacgttt ggaatgaaaa
    15901 gaaattggaa gaactattta atcgtctcaa tccaaatcgt gccttgagat tggcacgaac
    15961 taaaaaggaa aatccatctc agtaaagaag ctaaaaaatc ccgtgcctca tcagacacgg
    16021 gattttgtgg tacgacaggc atgtatagca aactgaatct ggaatagcac agcatatctt
    16081 ctaaaatatt gttataaatt gatttgaatt tcaaaattaa attgtttgat tcttatctca
    16141 atttgttata gtatatctga tgtcaaagtt ctcggcgagt caaatagcga ttcccaagcc
    16201 tgactatcgt gaggtagcgg attaaaatgg tctggggata gaccgtttta agtctgacgc
    16261 tggaaataag aattgtcaga agaagggata gcgaaatcgt ggctctacga acaggaacgt
    16321 gataataagg cgtatatagc ggataagagg gcctcaaact ctaaagtcca aaaaggtagt
    16381 cgtaacctat atgcgtaaat cacgagagta attgaattcg tactaagatt ttctattttc
    16441 actgtaacct tttaacgtcc ttatatcttg tatacacgag gaaagatgta cgacttatcc
    16501 cgtgaggtct atcactataa agagaaaacg acagatagaa gtgatcctga gtcacggtta
    16561 tctttaaaat agattgtctg ataggacggt atgtataaaa cgcttctgtg aactgagaga
    16621 agggggagaa gttcttgcta aaatttagtt gaacagccgt attccgatac ttagataaga
    16681 gatctagtct tagctcctac tcagttttag gggataaaaa aggggaaata gcgattcgag
    16741 aaagattata ctcttcgaaa atctcttcaa atcacgtcaa tatcgccttg ccgtatgtgt
    16801 aggatactga ctacgtcagt tccatctaca acctcaaaac agtgttttga gcaacctgcg
    16861 gctagtttcc tagtttgatc tttgattttc attgagtatt agtaattcag ttactaactc
    16921 gtcaactctg atttatccaa taaaattgaa aaggatggaa aaaaggataa atttatgata
    16981 tactttattt tgaagacctt attagaaatc ttgaaagagt attgaaaact tagaatgaga
    17041 aaaattgtta tcaatggtgg attaccactg caaggtgaaa tcactattag tggtgctaaa
    17101 aatagtgtcg ttgccttaat tccagctatt atcttggctg atgatgtggt gactttggat
    17161 tgcgttccag atatttcgga tgtagccagt cttgtcgaaa tcatggaatt gatgggagct
    17221 actgttaagc gttatgacga tgtattggag attgacccaa gaggtgttca aaatattcca
    17281 atgccttatg gtaaaattaa cagtcttcgt gcatcttact atttttatgg gagcctctta
    17341 ggccgttttg gtgaagcgac agttggtcta ccgggaggat gtgatcttgg tcctcgtccg
    17401 attgacttac accttaaggc gtttgaagct atgggtgcca ctgctagcta cgagggagat
    17461 aacatgaagt tatctgctaa agatacagga cttcatggtg caagtattta catggatacg
    17521 gttagtgtgg gagcaacgat taatacgatg attgctgcgg ttaaagcaaa tggtcgtact
    17581 attattgaaa atgcagcccg tgaacctgag attattgatg tagctactct cttgaataat
    17641 atgggtgccc atatccgtgg ggcaggaact aatatcatca ttattgatgg tgttgaaaga
    17701 ttacatggga cacgtcatca ggtgattcca gaccgtattg aagctggaac atatatatct
    17761 ttagctgctg cagttggtaa aggaattcgt ataaataatg ttctttacga acacctggaa
    17821 gggtttattg ctaagttgga agaaatggga gtgagaatga ctgtatctga ggacagcatt
    17881 tttgtcgagg aacagtctaa tttgaaagca atcaatatta agacagctcc ttacccaggc
    17941 tttgcaactg atttgcaaca accgcttacc cctcttttac taagagcgaa tggtcgtggt
    18001 acaattgtcg atacgattta cgaaaaacgt gtaaatcatg tttttgaact agcaaagatg
    18061 gatgcggata tttcgacaac aaatggtcat attttgtaca cgggtggacg tgatttacgt
    18121 ggggccagtg ttaaagcgac cgacttaaga gctggggctg cactagtcat tgctgggctt
    18181 atggctgaag gtaaaactga aattaccaat atcgagttta tcttacgtgg ttattctgat
    18241 attatcgaaa aattacgtaa tttaggagcg gatattagac ttgttgagga ttaaaccgta
    18301 gaggtgttta tgaatatttg gaccaaatta gcaatgtttt ctttttttga aacggatcgc
    18361 ttgtatttgc gtcctttctt ttttagtgat agtcaggact tccgcgagat agcttcaaat
    18421 ccagaaaatc ttcaatttat tttcccaacg caggcaagtc tggaagaaag tcaatatgca
    18481 ctggccaatt actttatgaa gtcccctttg ggagtgtggg caatttgtga ccagaaaaat
    18541 caacaaatga ttggttctat taaatttgag aagttagatg aaatcaaaaa agaagctgag
    18601 cttggctatt ttttgagaaa agatgcttgg tcgcaaggat ttatgacaga ggttgttaga
    18661 aaaatttgtc agctttcttt tgaggaattt ggcttaaaac aattatttat cattacccac
    18721 cttgaaaatg aagctagcca aagagttgct cttaagtctg gatttagttt gttccgtcag
    18781 tttaagggaa gtgatcgtta cacaagaaaa atgcgggatt atcttgaatt tcggtatgta
    18841 aaaggagagt tcaatgagta agcatcagga aattctaagc tatttggagg aattaccagt
    18901 aggtaaaagg gtcagtgttc gtagcatttc gaatcatcta ggagttagtg atggaacagc
    18961 ctatcgagct attaaagaag ctgaaaaccg tggaattgtg gagacccgtc ctagaagtgg
    19021 aacaattcgt gttaaatccc agaaagttgc tatagataga ttaacgtttg ctgaaattgc
    19081 agaagtgact tcttctgagg ttctggctgg gcaagaaggt ttagagagag aatttagtaa
    19141 gttttcaatt ggtgccatga ctgaacaaaa tatcttgtct taccttcatg atggggggct
    19201 cttgattgtc ggagaccgaa cccgtattca gttgctagcc ttggaaaatg aaaatgcagt
    19261 tctggttaca gggggatttc aggttcatga tgatgtgctt aaactggcca atcaaaaagg
    19321 gattcctgtt ctaagaagta agcatgatac ctttaccgtc gctaccatga tcaataaagc
    19381 cttgtcaaat gtccaaatca agactgatat tctgacagtt gagaaacttt atcgccctag
    19441 tcatgagtat ggttttctga gagagacaga tacagttaaa gattatttgg acttggttcg
    19501 taagaatcgt agcagccgtt tccctgttat caatcaacat caggtcgttg ttggcgttgt
    19561 aaccatgaga gacgctggtg ataaatcacc aagcacgaca attgataagg ttatgtctcg
    19621 tagtctattt ttggttggat tatcgacaaa tattgccaat gtgagtcaac ggatgatcgc
    19681 agaagacttt gaaatggtac cagttgttcg aagcaatcaa actttgcttg gcgttgtgac
    19741 gcgacgagat gtcatggaga agatgagccg ttcccaagtt tcggctctac caactttttc
    19801 tgagcagatt ggacaaaagc tctcttatca ccatgatgaa gtagtcatta cagtggaacc
    19861 ctttatgcta gaaaaaaatg gagttttggc taatggtgta ttggcagaaa ttctgaccca
    19921 catgacccaa gatttagttg ttaatagtgg tcgcaatctc attatcgagc agatgctgat
    19981 ctactttttg caggccgttc agatagatga tatattgcgc attcaggcac ggattattca
    20041 tcatacgaga cggtcagcta taattgatta cgatatttat catggtcacc agattgtttc
    20101 aaaagcaaat gtgactgtta aaattaatta gaaactagga gaaaagatga taacattaaa
    20161 atcagctcgt gaaatcgaag ctatggacaa ggctggtgat tttctagcaa gtattcatat
    20221 aggcttacgt gatttgatta agccaggcgt agatatgtgg gaagttgaag aatatgtccg
    20281 ccgtcgttgt aaagaagaaa atttccttcc acttcagatt ggggttgacg gtgccatgat
    20341 ggactatcct tatgctacct gttgctctct taacgatgaa gtggctcacg ctttccctcg
    20401 tcattatatc ttgaaagatg gtgatttgct caaagttgat atggttttgg gaggtcccat
    20461 tgctaaatct gacctaaatg tctcaaaatt aaacttcaac aatgttgaac aaatgaaaaa
    20521 atacactcag agttattctg gtggtttagc agactcatgt tgggcttatg ctgttggtac
    20581 accgtccgaa gaagtcaaaa acttgatgga tgtaaccaaa gaagctatgt acaagggtat
    20641 tgagcaagct gttgttggaa atcgtatcgg tgatatcggt gcggctattc aagaatacgc
    20701 tgaaagtcgt ggttacggtg tagtgcgtga tttggttggt catggtgttg gcccaactat
    20761 gcacgaagaa ccaatggttc ctaactatgg tattgcaggt cgtggactcc gtcttcgtga
    20821 aggaatggtc ttaaccattg aaccaatgat caatacaggc gattgggaaa ttgatacaga
    20881 tatgaaaact ggttgggcgc ataagaccat tgacggtgga ttgtcatgtc agtatgaaca
    20941 ccaatttgtc attacgaaag atggacctgt tatcttgact agccaaggtg aagaaggaac
    21001 ttattaataa aaagtgaaaa gactactgga agtttattat gaaaaaatcc agtagatctt
    21061 ttcataataa aacgcattgt atcaagtgtt aggggctgat atcatgcgtt tttctgcttt
    21121 taagattttt tccaactctg tttgtaagcg catcataaca aagggtctag gattcagggc
    21181 tctcctccta tatactatta gtaaagtaaa actaagggag gatattttag tgtcgcagtc
    21241 tattgttcct gtagagattc cacaatattg tcgttttgat tctaaaaaga gaaatggaat
    21301 tctgtttaat gttcgtattg ccaatcttaa atttaccttt tttagattag acttcctgcg
    21361 aaacaaaaca tggtatagta gttctatgaa tgatgaagca agtaaacaac taac
//
LOCUS       DAVBEO010000038        21102 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 009
            SAMEA1678075-rid20185393.denovo.038, whole genome shotgun sequence.
ACCESSION   DAVBEO010000038 DAVBEO010000000
VERSION     DAVBEO010000038.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678075
            Sequence Read Archive: ERR226392
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 21102)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21102)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980207.1
            Genome Coverage       :: 150x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:50:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 72 of 147
            Pseudo Genes (incomplete)         :: 72 of 147
            Pseudo Genes (internal stop)      :: 42 of 147
            Pseudo Genes (multiple problems)  :: 32 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21102
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678075-rid20185393.denovo.038"
                     /strain="KS 009"
                     /db_xref="taxon:1313"
     gene            <1..266
                     /locus_tag="VQ543_001451"
     CDS             <1..266
                     /locus_tag="VQ543_001451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HET2612161.1"
                     /translation="SIDERLRTRLRVIIWKQWKKKSRRLWGLLKLGVPKWIADKVSGW
                     GDHYQLVAQKSVLKRAISKPVLEKRGLVSCLDYYLERHALKVS"
     gene            720..1413
                     /locus_tag="VQ543_001452"
                     /pseudo
     CDS             720..1413
                     /locus_tag="VQ543_001452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809626.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
     gene            1469..1741
                     /locus_tag="VQ543_001453"
     CDS             1469..1741
                     /locus_tag="VQ543_001453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase"
                     /protein_id="HET2612162.1"
                     /translation="MFLLFSALVGMLSQLKEVPESVFLQETVEENHLVNVYSVLEVIS
                     TLAFSVFVLLMSYITESFGISISFWLSAICLMIEAILIYIRRDYFK"
     gene            2055..2186
                     /locus_tag="VQ543_001454"
     CDS             2055..2186
                     /locus_tag="VQ543_001454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000813667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="teichoic acid D-Ala incorporation-associated
                     protein DltX"
                     /protein_id="HET2612163.1"
                     /translation="MKQRKELYLFLGRTALYFLIFLGLLYFFSYLGQGQGSFIYNEF"
     gene            2207..3757
                     /gene="dltA"
                     /locus_tag="VQ543_001455"
     CDS             2207..3757
                     /gene="dltA"
                     /locus_tag="VQ543_001455"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012972622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltA"
                     /protein_id="HET2612164.1"
                     /translation="MSNKPIADMIETIEHFAQTQPSYPVYNVLGQEHTYGDLKADSDS
                     LAAVIDQLGLPEKSPVVVFGGQEYEMLATFVALTKSGHAYIPIDSHSALERVSAILEV
                     AEPSLIIAISAFPLEQVSTPMINLAQVQEAFVQGNNYEITHPVKGDDNYYIIFTSGTT
                     GKPKGVQISHDNLLSFTNWMIMDKEFATPSRPQMLAQPPYSFDLSVMYWAPTLALGGT
                     LFTLPSVITQDFKQLFAAIFSLPIAIWTSTPSFADMAMLSEYFNSEKMPGVTHFYFDG
                     EELTVKTAQKLRKRFPNARIINAYGPTEATVALSAVAVTDEMLATLKRLPIGYTKADS
                     PTFIIDEEGNKLPNGEQGEIIVSGPAVSKGYMNNPEKTAEAFFEFEGLPAYHTGDVGT
                     MTDEGLLLYGGRMDFQIKFNGYRIELEDVSQNLNKSRFIESAVAVPRYNKDHKVQNLL
                     AYVILKDGVREQFERDIDITKAIKEDLTDIMMSYMMPSKFLYRDSLPLTPNGKIDIKG
                     LINEVNKR"
     gene            3754..4998
                     /gene="dltB"
                     /locus_tag="VQ543_001456"
     CDS             3754..4998
                     /gene="dltB"
                     /locus_tag="VQ543_001456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000969717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltB"
                     /protein_id="HET2612165.1"
                     /translation="MMEFFQQLPHLEPYGNPQYFVYVIAATLPIFIGLFFKKRFAWYE
                     VLVSLFFIVTMLVGGKTNQLAALGIYLCWEILLLLFYKHYRKSKDGKWVFYLVSFLSL
                     LPIIFVKVQPAINGTQSLLGFLGISYLTFRSVGIIIELRDGVIKDFTLWEFLRFLLFM
                     PTFSSGPIDRFKRFNENYQAIPERDELMDMLDESVRYIMWGFLYKFILAHVLGETLLP
                     PLKNLALQSGGFFNLYALAVMYTFGLELFFDFAGYSMFALAISNLMGIRSPINFNKPF
                     LSRDLKEFWNRWHMSLSFWFRDFVFMRMVMVLTRKKVFKNRNVTSSMAYIVNMLIMGF
                     WHGVTWYYIAYGLFHGLGLVINDAWVRKKKTLNKERKKAGKAALPENRWIQLLGMVVT
                     FHVVMLSFLIFSGFLNNLWFKK"
     gene            5012..5251
                     /gene="dltC"
                     /locus_tag="VQ543_001457"
     CDS             5012..5251
                     /gene="dltC"
                     /locus_tag="VQ543_001457"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005591431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltC"
                     /protein_id="HET2612166.1"
                     /translation="MDIKSEVIEIIDELFMEDVSDMMDEDLFDAGVLDSMGTVELIVE
                     IENRFDIRVPVTEFGRDDWNTANKIIAGIVELQNA"
     gene            5244..6512
                     /gene="dltD"
                     /locus_tag="VQ543_001458"
     CDS             5244..6512
                     /gene="dltD"
                     /locus_tag="VQ543_001458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000919885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltD"
                     /protein_id="HET2612167.1"
                     /translation="MLKRLWMIFGPVLIAGLLVFLLIFFYPTEMHHNLGAEKRSAVAT
                     TIDSFKERSQKVRALSDPNVRFVPFFGSSEWLRFDGAHPAVLAEKYNRSYRPYLLGQG
                     GAASLNQYFGMQQMLPQLENKQVVYVISPQWFSKNGYDPAAFQQYFNGDQLTSFLKHQ
                     SGDQASQYAATRLLQQFPNVAMKDLVQKLASKEELSTADNEMIELLARFNERQASFFG
                     QFSVRGYVNYDKHVAKYLKILPDQFSYQAIEDVVKADAEKNTSNNEMGMENYFYNEQI
                     KKDLKKLKDSQKSFTYLKSPEYNDLQLVLTQFSKSKVNPIFIIPPVNKKWMDYAGLRE
                     DMYQQTVQKIRYQLESQGFTNIADFSKDGGEPFFMKDTIHLGWLGWLAFDKAVDPFLS
                     NPTPAPTYHLNERFFSKDWATYDGDVKEFQ"
     gene            6667..7107
                     /gene="adcR"
                     /locus_tag="VQ543_001459"
     CDS             6667..7107
                     /gene="adcR"
                     /locus_tag="VQ543_001459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001249319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-dependent transcriptional regulator AdcR"
                     /protein_id="HET2612168.1"
                     /translation="MRQLAKDINAFLNEVILQAENQHEILIGHCTSEVALTNTQEHIL
                     MLLSEESLTNSELARRLNVSQAAVTKAIKSLVKEGMLETSKDSKDARVIFYQLTDLAR
                     PIAEEHHHHHEHTLLTYEQVATQFTPNEQKVIQRFLTALVGEIK"
     gene            7107..7811
                     /locus_tag="VQ543_001460"
     CDS             7107..7811
                     /locus_tag="VQ543_001460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001269494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HET2612169.1"
                     /translation="MRYITVEDLSFYYDKEPVLEHINYCVDSGEFVTLTGENGAAKTT
                     LIKASLGILQPRIGKVAISKTNTQGKKLRIAYLPQQIASFNAGFPSTVYEFVKSGRYP
                     RKGWFRRLNTHDEEHIKASLDSVGMWEHRDKRLGSLSGGQKQRAVIARMFASDPDVFI
                     LDEPTTGMDAGSKNEFYELMHHSAHHHGKAVLMITHDPEEVKDYADRNIHLVRNQDSP
                     WRCFNVHENGQEVGHA"
     gene            7804..8610
                     /locus_tag="VQ543_001461"
     CDS             7804..8610
                     /locus_tag="VQ543_001461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HET2612170.1"
                     /translation="MLSLLSYDFIQRAFLAVIAMSLFSPVLGTFLILRRQSLMSDTLS
                     HVSLSGVAFGLVLGISPTVSTIAIVLIAAVFLEYLRTVYKSFMEIGTAILMSTGLAVS
                     LIVMSKGRSSSSMSLDQYLFGSIVTISEEQVISLFVIAAVVLILTFLFLRPMYILTFD
                     EDTAFVDGLPVRTMSILFNMVTGVAIALMIPAAGALLVSTIMVLPASIALRLGKNFKS
                     VMLLASAIGFLGMVAGLYISYYAETPASASITIIFVTVFILISLVRRFIK"
     gene            8620..10125
                     /gene="adcA"
                     /locus_tag="VQ543_001462"
     CDS             8620..10125
                     /gene="adcA"
                     /locus_tag="VQ543_001462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000724057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding
                     lipoprotein AdcA"
                     /protein_id="HET2612171.1"
                     /translation="MKKISLLLASLCALFLVACSNQKQADGKLNIVTTFYPVYEFTKQ
                     VAGDTANVELLIGAGTEPHEYEPSAKAVAKIQDADTFVYENENMETWVPKLLDTLDKK
                     KVKTIKATGDMLLLPGGEEEEGDHDHGEEGHHHEFDPHVWLSPVRAIKLVEHIRDSLS
                     ADYPDKKVTFEKNAAAYIEKLQALDKAYAEGLSQAKQKSFVTQHAAFNYLALDYGLKQ
                     VAISGLSPDAEPSAARLAELTEYVKKNKIAYIYFEENASQALANTLSKEAGVKTDVLN
                     PLESLTEEDTKAGENYISVMEKNLKALKQTTDQEGPAIEPEKAEDTKTVQNGYFEDAA
                     VKDRTLSDYAGNWQSVYPFLEDGTFDQVFDYKAKLTGKMTQAEYKAYYTKGYQTDVTK
                     INITDNTMEFVQGGQSKKYTYKYVGKKILTYKKGNRGVRFLFEATDADAGQFKYVQFS
                     DHNVAPVKAEHFHIFFGGTSQEALFEEMDNWPTYYPDNLSGQEIAQEMLAH"
     gene            complement(11245..12018)
                     /locus_tag="VQ543_001463"
     CDS             complement(11245..12018)
                     /locus_tag="VQ543_001463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HET2612172.1"
                     /translation="MIKDERVLELIEIIKKKKRIAVKELAEITFSSTSTLRRDLIFLE
                     NQGLIKRKHGYVTLSSMNTIELSHQIREGESTRQKRLIASLAKDFIRSGMCIYLDSST
                     TVYELCPYLSELDNLIIFTNGLHTAQTLSETVKDSSKIFITSGEVKHQSCSVVNYDKE
                     NSLLDHFNIDLAFCSARGIDDQYVYEASLSQAISKKNIIDKAHETILLIDSSKFYKTG
                     FFKINPLSKYTTFISDTLPDQKLLDAVELFDGEWVSDIQ"
     gene            12194..13597
                     /locus_tag="VQ543_001464"
     CDS             12194..13597
                     /locus_tag="VQ543_001464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000388528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnulokinase"
                     /protein_id="HET2612173.1"
                     /translation="MEAVLAIDLGATSGRAIVGYLSENKLVMEEINRFSNLPIRVKGH
                     LSWDIDFLLAKILESIRLANTSYKILSIGIDTWGVDFGLIDNEGKLLSQPVHYRDERT
                     KGVLKEISEMTELEKLYSETGNQIMEINTLFQLFKARQESPDSFYKTNKILLMPDLFN
                     YLLTGKFATEKSIASTTQLFDPRSQNWNQNILKLFELDSSLLPEIVSEGNVLGRIKKE
                     YGLGDIPVVNVCSHDTASAIVSVPKTEGSLFISSGTWSLVGVELTSPILTTESFSYGF
                     TNEVGKDGVITFLKNCTGLWIIEELRRSFERRGKAYSFDDIRTMVEKEKENLPLIDTE
                     STEFATESDMHKTLTEYLAYHHETREWTDGQLFKIVYESLAETYRKAIELLEELTHKV
                     YKRIYVIGGGARASYFNQMIADRTGKEVLTGLTEATAVGNIVVQLIAMGQLKGMEEAH
                     HVIEEFLQLESYYSQKN"
     gene            13712..14350
                     /locus_tag="VQ543_001465"
     CDS             13712..14350
                     /locus_tag="VQ543_001465"
                     /EC_number="4.1.2.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001286141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-fuculose-phosphate aldolase"
                     /protein_id="HET2612174.1"
                     /translation="MSDVKQELIKYGKKLVETDLTKGTGGNLSVFDREKQLMAITPSG
                     IDFFEIKESDIVVMDINGNVVEGERLPSSEWYMHLIQYQTRDDIDAIIHAHTTYATVL
                     ACLREPLPASHYMIAVAGKDVRVAEYATYGTKELAVNAAKAMEGRRAVLLANHGILAG
                     AQNLLNAFNIVEEVEYCAKIYCLAKNFGEPVVLPDEEMELMAEKFKTYGQRK"
     gene            14362..14802
                     /locus_tag="VQ543_001466"
     CDS             14362..14802
                     /locus_tag="VQ543_001466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000912112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RbsD/FucU family protein"
                     /protein_id="HET2612175.1"
                     /translation="MLKHIPKNISPDLLKTLMEMGHGDEIVLADANYPSASCANKLIR
                     CDGVNIPELLDSILYLMPLDSYVDSSIQFMNVVSGDDIPKIWGTYRQMIEGHGTDLKT
                     ITYLRREDFYERSKKAYAIVATGETSLYANIILKKGVVVERENV"
     gene            14795..15226
                     /locus_tag="VQ543_001467"
     CDS             14795..15226
                     /locus_tag="VQ543_001467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000483177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HET2612176.1"
                     /translation="MFNRGILVASHGDFASGALMTAEMFVGETTNDRVRTLGLMPGEN
                     IVEFEHYFKNQVDELLDSNQEVIVLTDLIGGSPNNVALSRFLNLDSVDIVTGFNIPLL
                     VELISNYDSKINLEEIVHNAQNSLFNVKQQLNVEEEENLCL"
     gene            15217..15687
                     /locus_tag="VQ543_001468"
     CDS             15217..15687
                     /locus_tag="VQ543_001468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000020992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HET2612177.1"
                     /translation="MSIEFVRIDDRLVHGQVVTTWLKKYDIEQVIIVNDRISEDKTRQ
                     SILKISAPVGLKIVFFSVKRFVEVLNSVPIKKRTMLIYTNPKDVYDSIEGNLKLEYLN
                     VGQMSKTEENEKVTGGVALGEEDKYYFKKIVDKGTRVEIQMVPNDKVTMLEKFL"
     gene            15712..16485
                     /locus_tag="VQ543_001469"
     CDS             15712..16485
                     /locus_tag="VQ543_001469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000899624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HET2612178.1"
                     /translation="MLFTQALLVTLVGIIATIDYNGPLFMIHRPLVTSAMVGLVLGDF
                     TQGVLIGSALELTWLGVTGIGGYTPPDTISGAIIGTAFGILSGQGETAGIAIAVPIAV
                     ATQQLDVLAKTLDVYFVKKADNDAKNGDYSKIGFYHYSSLVLITLFKIVPIFLAIMLG
                     GEYVADLFAKVPPIVMQGLNSAGALLPSIGFGMLLNMMLKKNMWVFLLIGFICSVYGG
                     MSTIGISLVGIAVAYFYDMIGSKPQETTSSSDVEEDLDL"
     gene            16482..17282
                     /locus_tag="VQ543_001470"
     CDS             16482..17282
                     /locus_tag="VQ543_001470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HET2612179.1"
                     /translation="MMNNKVTKVELKKVFKRSFMYGSSWNYERMQNLGFLYTILPVLK
                     KLYPDKDSASPAMKRHLEFFNTHQTAAPFILGVTSAMEEQEGNEGAASITGIKVGLMG
                     PLAGLGDSLFWLTLVPICFSIGASYSKDGGALGIFIALILFNIINIPVKYFGLKYGYT
                     KGSSLIQENNTKGTLNRVTSMATALGLVLVGGLIPSMVGINFGLEFKQGELVISVQEM
                     ITKLIPGFIPMALTLLMCKLIRKGKNPVVLIFSVMAIGVILVVLGILK"
     gene            17341..19635
                     /locus_tag="VQ543_001471"
     CDS             17341..19635
                     /locus_tag="VQ543_001471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 95 protein"
                     /protein_id="HET2612180.1"
                     /translation="MKLWYKKAASNWNEALPIGNGHLGGMIYGSATKECIQLNDETIW
                     YRGKSDRNNPDSLLHLKKIREYLLDGEIQKAEELIKLTMFATPRDQSHYELLGELYIE
                     HIDIQSCALSLYERELDLDTAISNVVFEPNSCNLQIKREYFTSFNKNILCCRIVSSVQ
                     NTLNLNINLGRNKRFNDEVSKLDSSTILMSASAGGRKGVQFKVVCHSKVTDGEVSVLG
                     ETIVIRNATEVFLYLKSMTDYWGNIDISSLQGEFSSIDYFTEKDEHVKKYQEQFNRVD
                     FKLDYSKDCLSIPTNLLLENTKKYSNYLTNLLFHYGRYLLISSSQPNGLPVNLQGIWC
                     DELNPIWGSKYTININTQMNYWMVGPCDLPEVEYPLFDMLERMREPGRLTAKKMYGAR
                     GFTAHHNTDGFGDTAPQSHAMGAAIWVLTIPWLCTHIWEHYLYFQDERILTEHFEMIK
                     EAFLFFEDYLFEVDGYLMTGPSVSPENKYRLKNGIEGNACLSSTIDNQILRYFCDSCI
                     GIAKQLGDNSDFISRVKELKKKLPKTKIGSNGQIQEWLEDYEEVEPGHRHISPLFGLY
                     PYNEIDIHKTPELAEAAKITINRRLSNANFLSSQEREQAINNWLVSGLHASTQTGWSA
                     AWLIHFFARLYQGEPAYNQINGLLNNATLGNLFLDHPPFQIDGNLGLVSGICELLVQS
                     HHNWLSLIPALPSAWSEGEVKGFRVRGGYKVSFAWKNGDITFLKLEGGNKDQKVRVRI
                     YGKNTDVQNIELVFNSEKIIELNF"
     gene            19645..>21102
                     /locus_tag="VQ543_001472"
     CDS             19645..>21102
                     /locus_tag="VQ543_001472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001031112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2612181.1"
                     /translation="MNKEKIKRKLITILFVCIGMLCFGLLAGVKADNRVQMRTTINNE
                     SPLLLSPLYGNDNGNGLWWGNTLKGAWEAIPEDVKPYAAIELHPAKVCKPTSCIPRDT
                     KELREWYVKMLEEAQSLNIPVFLVIMSAGERNTVPPEWLDEQFQKYSVLKGVLNIENY
                     WIYNNQLAPHSAKYLEVCAKYGAHFIWHDHEKWFWETIMNDPTFFEASQKYHKNLVLA
                     TKNTPIRDDAGTDSIVSGFWLSGLCDNWGSSTDTWKWWEKHYTNTFETGRARDMRSYA
                     SEPESMIAMEMMNVYTGGGTVYNFECAAYTFMTNDVPTPAFTKGIIPFFRHAIQNPAP
                     SKEEVVNRTKAVFWNGEGRISSLNGFYQGLYSNDETMPLYNNGRYHILPVIHEKIDKE
                     KISSIFPNAKILTKNSEELSSKVNYLNSLYPKLYEGDGYAQRVGNSWYIYNSNANINK
                     NQQVMLPMYTNNTKSLSLDLTPHTYAVVKENPNNLH"
BASE COUNT         6542 a         3448 c         4467 g         6645 t
ORIGIN      
        1 ccagcataga tgagcgcttg cgtactcgcc tacgagtgat tatctggaag caatggaaga
       61 agaaatcgag acgattatgg ggattgctta agttaggagt tcctaaatgg atagcagata
      121 aggtatctgg ctggggcgac cattatcaat tagtagctca gaagtcggta cttaaacgtg
      181 ctatatcaaa accagtcctg gaaaaacgtg gactggtttc gtgtttggat tattaccttg
      241 aacgacatgc gttaaaagtt agttgaaccg ccgtatgccg aacggcacgt acggtggtgt
      301 gagaggggct agagattatc ctctactcga ttaactcccc tgaaatttgt tttaattatg
      361 caaatttcac gtatttttga tgctgagacg acgatcctgg gaacttttca gatatttttt
      421 tgactatcta aaatctatca ttagaaaagc ttagagcgcc aaaggatttg agcgtttttc
      481 tgatttttaa gactttttcc cagtctcttt ttcgattgaa gatgtaatta ttctactaac
      541 taacttctta gtactagcca acaacgataa tcataattcc tcctaaaatt aggaataata
      601 aaggcaatag tttttgtttt ttcatgtaaa aaacctcact tttgttttct gctattttat
      661 gctaaaatat taaaaatcaa atttaattcc aaagtttgta actaaagggg gagcgctaca
      721 tgtctaattc atttgtcaag ttgttagtct ctcaattatt tgcaaattta gcagatattt
      781 tctttagagt aacaatcatt gctaacatat acattatttc aaaatcagta attgccacat
      841 cactagttcc tatcttaata ggaatatcct cttttgttgc gagtctttta gttccgttgg
      901 ttactaaaag gttagcgcta aatagggttt tatctttatc tcaatttgga aagactatat
      961 tattggcgat actggtagga atgtttaccg taatgcaatc cgtagcgcct ttggtgacct
     1021 atctatttgt tgttgcaatt tccatactag atggttttgc agcacccgtt tcctatgcta
     1081 ttgtgccacg ctatgcgacc gatttgggta aggctaattc agccttatca atgactggtg
     1141 aagctgttca attgataggt tggggattag gtggactctt gtttgcaaca attggtctgt
     1201 tacctaccac gtttatcatt ttagtcttgt atatcatttc tagctttctg atgttatttc
     1261 ttcctaacgc tgaagtggag gtgttagagt cagaaactaa tcttgaaatt ttgctcaaag
     1321 gttggaagtt agttgctaga aatcctagat taagactttt tgtatcagca aatttattgg
     1381 aaattttttc aaatacgatt tgggtttctt ccattttgta gctatggcaa tagtgacact
     1441 gactattcta tattttccaa acgcacagat gtttttatta ttttcagctt tagttggtat
     1501 gttatcgcaa ctaaaagaag ttcctgaaag tgtatttctt caggaaacag tagaggaaaa
     1561 tcatttagtt aatgtctatt ccgttcttga agtgatttct acattagcat tttcagtatt
     1621 tgttttgcta atgagctata ttactgagag ttttggtatt agcatcagtt tttggctatc
     1681 agccatttgt ctgatgatag aagctatttt aatttatatc agacgagatt attttaaatg
     1741 agagagtggt taaaaagtct ttaaaaatca gaaaagcgca tagtatcagg tgttgaaaaa
     1801 acttgatatt gtgtgtttta ttatgggaag atttacttca ttgtctcctg aaatggagtt
     1861 ttgaagcagg atcactctat ttgaaaatat acatagaaaa actgtataat ccttaaaata
     1921 agctgaaatc tattggaaac atacggtaaa caattgaaaa ggtactatat aaagtggtac
     1981 aatggtagaa aaataagcta gtaagaatca ctcttatttt agcgaaaaat tacagaaatg
     2041 aatggttttt cttgatgaaa cagagaaaag aattgtacct ctttcttggt cggacagcct
     2101 tgtattttct tatctttcta gggctgcttt acttctttag ctatcttggt cagggtcaag
     2161 gaagctttat ctataatgaa ttttaacttg aaggagaatc cctattgtgt caaataaacc
     2221 aatagcagat atgattgaaa ccattgagca ttttgctcag acacagccta gctatcctgt
     2281 ctataatgtt ttggggcagg aacacactta tggcgattta aaggctgatt cggatagttt
     2341 ggctgcagtc attgaccaac taggcttgcc tgagaagtct cctgtggttg tttttggtgg
     2401 ccaagaatat gaaatgttgg caacctttgt agcgctgact aagtcaggtc atgcctacat
     2461 tccaattgat agccattcgg ccttggagcg agtttcagct attttagaag tagcagagcc
     2521 aagcttgatt attgccattt cagcctttcc cttggagcag gtttctacac caatgataaa
     2581 tctagctcag gttcaagaag cctttgttca agggaataac tatgaaatca cgcatccagt
     2641 caagggagat gataattact acattatctt tacttctggt acgactggta agcctaaggg
     2701 agtgcagatt tcacatgata atctcctcag ctttacaaac tggatgatta tggataagga
     2761 atttgcgaca ccgagtcgtc cgcaaatgct ggcacagcca ccttattctt ttgacttgtc
     2821 tgtcatgtat tgggcaccga ccttggcact tggtggtacg cttttcactc ttccttcagt
     2881 catcactcag gactttaagc aactctttgc ggctatcttt tcattgccaa tcgctatctg
     2941 gacatcaaca ccatcctttg cagatatggc catgttgtct gaatacttca acagtgagaa
     3001 aatgcctgga gtcacgcatt tctactttga tggtgaagaa ttgacggtca aaacagctca
     3061 aaaactgcgc aagcgtttcc caaatgcccg tatcatcaat gcttacggcc caacagaagc
     3121 gacagtagct ctgtcagcag ttgccgtgac agacgagatg ttagcgactc tcaaacgcct
     3181 accaatcggc tataccaagg ctgattctcc aacctttatc attgacgagg aaggaaataa
     3241 actgccaaat ggcgaacagg gagaaatcat tgtttctggg ccagctgttt caaaaggtta
     3301 tatgaacaat cctgaaaaaa cagcagaagc cttctttgag tttgaaggtc tgccagccta
     3361 tcacacaggc gatgtgggaa ccatgacaga tgagggcttg cttctctacg gcggacgcat
     3421 ggacttccag attaagttta acggttaccg cattgagtta gaagatgtct ctcaaaacct
     3481 caacaagtct cgctttatcg aatctgctgt cgcagtaccg cgctataaca aggaccacaa
     3541 ggtacaaaat ctattggctt atgtcatctt aaaagacggt gttcgtgagc agtttgagcg
     3601 agatatcgat attaccaagg ccatcaagga agacctgaca gacatcatga tgtcctatat
     3661 gatgccatct aaattccttt accgagacag tttgccactg actccaaatg gaaagattga
     3721 catcaaagga ttgattaacg aggtgaataa gagatgatgg agttttttca acagcttcct
     3781 catttagagc catatggcaa tcctcagtat tttgtttatg tgattgctgc aaccttgccc
     3841 atctttatag gtctcttttt caagaaacgc tttgcctggt atgaagtgtt ggtaagtctc
     3901 ttctttattg tcaccatgtt ggtgggtgga aagaccaatc aactagctgc cttgggtatt
     3961 tacctttgct gggaaatatt gctcctgctt ttctacaagc attatcgaaa aagcaaggat
     4021 ggcaagtggg tcttctactt agttagtttt ctgtccctac ttccgattat ctttgtcaag
     4081 gtgcaaccag ctatcaatgg aacgcagtct ttgcttgggt tcttgggaat ttcttatctt
     4141 acctttcgtt cggttgggat tatcatcgag ctgagagatg gagtgattaa ggattttacc
     4201 ctctgggaat tcctccgttt ccttctcttc atgccaactt tctcgagtgg tccaatcgat
     4261 cgctttaagc gatttaatga aaattatcag gctattcctg agcgagatga gttgatggat
     4321 atgctggatg aatctgtccg ctatatcatg tggggctttt tgtataagtt tatcctagct
     4381 catgttttag gagagacctt actacctcct ctgaagaatt tagccttgca gtcaggtggc
     4441 ttctttaatc tctatgcctt ggcagttatg tatacttttg gtctggagct cttctttgac
     4501 tttgcaggtt attctatgtt tgctttggcc atctcaaact tgatgggaat ccgtagccct
     4561 atcaacttta acaagccctt tttatcaagg gatttaaagg agttttggaa tcgctggcat
     4621 atgagtctgt ccttctggtt ccgtgacttt gtctttatgc gaatggtgat ggtgttaacc
     4681 agaaagaaag tctttaaaaa tcgtaatgta acctcaagca tggcctacat tgtaaatatg
     4741 ctgattatgg gattttggca tggtgtgacc tggtactata tcgcctatgg actctttcat
     4801 ggactaggct tggtcatcaa tgatgcctgg gttcgcaaga aaaaaacact caataaggaa
     4861 cggaaaaaag cagggaaggc tgccctacct gagaatcgct ggattcagtt gcttggcatg
     4921 gttgtcactt tccatgttgt catgttgtca ttcttaatct tttctggatt cttgaataat
     4981 ctatggttta aaaaataaaa ggaaataaaa tatggatatc aaatcagaag ttatcgaaat
     5041 tattgatgag ttgtttatgg aagatgtttc tgacatgatg gatgaagatc tttttgatgc
     5101 aggtgtcttg gatagtatgg gaacggttga gttgattgtg gagattgaga accgttttga
     5161 cattcgtgtc cctgtaacag agtttggtcg tgacgactgg aatacagcta ataaaatcat
     5221 agctggtatt gtggagctac aaaatgctta aacgcttatg gatgatcttc ggaccggtct
     5281 tgatcgctgg tttgttggtt tttctgctca ttttctttta tcctactgag atgcatcata
     5341 atctaggagc tgaaaagcgt tcagcagtgg ctactactat cgatagtttt aaggagcgaa
     5401 gtcaaaaagt cagagcacta tctgatccaa atgtgcgttt tgttcccttc tttggctcta
     5461 gtgaatggct tcgttttgac ggtgctcatc ctgcggtatt agctgagaaa tacaatcgtt
     5521 cctaccgtcc ttatctttta ggacaggggg gagctgcatc gcttaaccaa tattttggaa
     5581 tgcaacagat gttaccacag ctggagaata aacaagttgt gtatgttatc tcacctcagt
     5641 ggttcagtaa aaatggctat gatccagcag ccttccagca gtattttaat ggagaccagt
     5701 tgactagttt tctgaaacat caatctgggg atcaggctag tcaatatgca gcgactcgct
     5761 tactgcaaca gttcccaaac gtagctatga aggacctggt tcagaagttg gcaagtaaag
     5821 aagaattgtc gacagcagac aatgaaatga ttgaattatt ggctcgtttt aatgaacgcc
     5881 aagcttcctt ttttggtcag ttttcggtta gaggctatgt taactacgat aagcatgtag
     5941 ctaagtattt aaaaatcttg ccagaccagt tttcttatca ggcaatagaa gatgttgtca
     6001 aagcagatgc tgaaaaaaat acttccaata atgagatggg aatggaaaat tatttctata
     6061 atgagcagat caagaaggat ttgaagaaat taaaggattc tcagaaaagc tttacctatc
     6121 tcaagtcgcc agagtataat gacttgcagt tggttttaac acagttttct aaatctaagg
     6181 taaacccgat ttttatcatt ccacctgtta ataaaaaatg gatggactat gctggtctac
     6241 gagaggatat gtaccaacaa acggtgcaga agattcgcta ccagttagaa agtcaaggtt
     6301 ttaccaatat agcagatttt tctaaggacg gcggggagcc tttctttatg aaggacacca
     6361 ttcaccttgg ttggttgggt tggttggctt ttgacaaggc agttgatcct ttcctatcca
     6421 atcccacacc agctccgact taccatctga atgagcgctt tttcagcaaa gattgggcga
     6481 cttatgatgg agatgtcaaa gaatttcaat agataatata atatagaaga gttcaagaat
     6541 gaaactagtt ttcacgtttt ttcttgactc tttttttgct tgtgatataa ttaactggta
     6601 aacaaaatgt caaagaatag tatttttctc ttaaaaaaga gaagtctaaa aggaaaggag
     6661 tcagatatga gacagctagc aaaggatatc aatgcttttt tgaatgaggt gattttgcag
     6721 gcggaaaatc agcatgaaat cctaataggt cattgcacta gcgaggtggc cctgaccaat
     6781 actcaggagc atatccttat gctcttgtca gaggaatctt taacaaattc agaattggcc
     6841 cgtcgtctca atgtcagtca ggcggcagtt accaaggcca ttaagtcttt ggtcaaggaa
     6901 gggatgttgg aaacatctaa agattctaaa gatgcgcgtg tgatttttta tcagttgact
     6961 gacttggctc gtccaatcgc tgaggagcac caccatcacc atgagcatac acttttaacc
     7021 tatgaacaag tggcgactca gtttactcca aatgaacaaa aagtgattca gcggtttttg
     7081 actgctttag taggagaaat caaataatga gatatattac ggtagaggat ttgtccttct
     7141 attatgataa ggaacctgtt cttgaacata tcaattattg tgttgatagt ggggaatttg
     7201 ttaccttgac tggggaaaat ggagcggcta agacgacgct catcaaggcc agtcttggaa
     7261 ttctgcaacc acgcattgga aaggtggcta tttcaaagac aaatacgcaa ggtaagaaat
     7321 tgagaatagc ctatcttcct caacaaattg ccagttttaa tgctggtttt ccaagtacgg
     7381 tctatgaatt tgtcaagtcg ggtcgctatc cgagaaaagg ctggttccgt cgtttgaata
     7441 ctcatgatga ggagcatatc aaggctagtc tggactcagt tggcatgtgg gaacatcgag
     7501 acaaacgctt ggggtctcta tctgggggac aaaagcagcg agcggtaatt gcgcgtatgt
     7561 ttgcttctga ccctgatgtg tttatcctag acgagccgac aacggggatg gatgcaggaa
     7621 gtaaaaatga attttacgaa ctcatgcacc acagcgccca tcatcatggc aaggctgttt
     7681 tgatgattac ccatgaccct gaagaagtta aggattatgc ggatcgcaat attcatctag
     7741 tccgtaacca agactcgcca tggcgttgtt tcaacgttca tgagaatggg caggaggtgg
     7801 gccatgctta gtttattatc ttacgacttt atacaacgcg cctttttggc ggttattgct
     7861 atgagtcttt tctcaccggt attgggaacc ttcctcatct tgcgtcgtca gagtttgatg
     7921 agtgataccc ttagccacgt ctcactttca ggtgtagcct ttggtctggt tttggggatt
     7981 tctccaactg tttctactat tgccattgtc ttgattgcgg cggtctttct ggagtatctc
     8041 cgtacggttt acaagagctt tatggaaatc gggacagcta tcctcatgtc aacaggtttg
     8101 gctgtttctc tgattgtcat gagcaagggt agaagctcga gttcaatgag tttggaccaa
     8161 tatctctttg gttcgatcgt gactatcagt gaagaacagg tcatttccct ctttgtcatt
     8221 gcggcggttg ttttgatttt gacctttctc tttcttcgtc ctatgtatat cttaactttt
     8281 gacgaagata cggcctttgt ggatggcttg ccagttcgta ccatgtccat tctttttaac
     8341 atggtgacag gggtggctat tgcccttatg attcctgcag caggagctct tctggtatcg
     8401 accattatgg tcttgccagc tagtattgcc ctgcgtctgg ggaaaaactt taaatcggtt
     8461 atgctgcttg ccagtgcgat tggctttttg ggaatggtag caggacttta catttcctac
     8521 tatgcagaaa cacctgcaag tgcaagtatt accattattt ttgtaactgt ctttatacta
     8581 atcagtttag taagacgttt tatcaaatag gagacgaacg tgaaaaaaat tagcttatta
     8641 ctagccagtc tatgtgcctt gtttttagtg gcttgttcca atcaaaaaca ggcagatggt
     8701 aaactcaata tcgtgacaac cttttaccct gtctatgaat ttaccaagca agtcgcagga
     8761 gatacggcta atgtagaact cctaatcggt gctgggacag aacctcatga atacgaacca
     8821 tctgccaagg cagttgccaa aatccaagat gcagatacct tcgtttatga aaatgaaaac
     8881 atggaaacat gggtacctaa attgctagat accttggata agaaaaaagt gaaaaccatc
     8941 aaggcgacag gcgatatgtt gctcttgcca ggtggcgagg aagaagaggg agaccatgac
     9001 catggagaag aaggtcatca ccatgagttt gacccccatg tttggttatc accagttcgt
     9061 gccattaaac tagtagagca catccgcgac agcttgtcag cagattatcc tgataaaaaa
     9121 gtgacctttg agaagaatgc agctgcctat atcgaaaaat tgcaagcctt ggataaggct
     9181 tacgcagaag gcttgtctca agcaaaacaa aagagctttg tgactcaaca cgcagccttt
     9241 aactatcttg ccttggacta tggactcaaa caagtcgcaa tctcaggact ttctccagat
     9301 gcagagccat cagctgctcg cttggcagaa ttgacagagt atgtcaagaa aaataaaatc
     9361 gcctatatct attttgaaga aaatgcctca caagcccttg ctaacacact ttcaaaagaa
     9421 gcaggtgtca aaactgatgt cctcaatcct ttagaaagtc tgacagaaga ggacaccaag
     9481 gctggagaaa actacatttc cgtgatggag aaaaacctca aggctttgaa acaaacaaca
     9541 gaccaagaag gcccagcaat cgaacctgaa aaggcagagg ataccaagac agtccaaaat
     9601 ggttacttcg aggatgcagc tgtcaaggac cgcaccttga gtgactatgc aggtaactgg
     9661 caatcagttt atcctttcct tgaagacggc acgtttgacc aagtctttga ctacaaggct
     9721 aagttgactg gtaagatgac ccaggctgag tacaaggctt actatacaaa aggctatcag
     9781 acagatgtga ctaagattaa cattactgat aatactatgg aatttgttca aggtggacaa
     9841 agcaagaaat acacttacaa gtatgtcggt aagaaaattt tgacttacaa gaaaggcaat
     9901 cgtggcgtgc gtttcctctt tgaagccaca gatgctgacg ctggacaatt caagtatgtt
     9961 cagtttagtg atcacaatgt tgccccagtt aaggcagaac atttccatat cttctttgga
    10021 ggcacaagcc aagaagccct ctttgaagaa atggacaact ggccaaccta ctacccagat
    10081 aacctatctg gccaagaaat cgcccaagaa atgttggcgc attgatgaga aatcgactag
    10141 ttcataagag ctagtcggtt ttttgatact agatggctaa cttcattata gacctttcag
    10201 aactttaaac aataaataaa actcttgaaa tatctgggct tatatgctag aatgtagtta
    10261 gtgtataagg ttcattagaa caccaaagcc cctaactagt gccatagtta agggcttttt
    10321 tgacgtatct tagcgattta acgggtgttt ataggctagt cagtcggtct acttcttacc
    10381 atctagccat ttgcagacga aatacaagat aattccagct ataacatctg ctataatagt
    10441 aagagcaagc tctggtataa ggctcattag tttcacctcc tctcacgaac ccataggaac
    10501 gtaatcggta accgatgaca aaaatagtat accacactaa atttagatca tcaacctcac
    10561 ttaatgcttg aactattgta gattatatgc taaaatgtag ttaattgata aggttcatta
    10621 gaacaccaaa gcccctaact atggccgtag ttaagggctt ttttgacgta tcttagcgat
    10681 ttaacgggtg tttataggct agtcactcgg tctactcctt actatctagc catctgcaga
    10741 cgaaatacaa gataattcca gctataacat ccgctataat agtaagagcg agctctatga
    10801 taaggctcat tagtttcacc tcctctcacg aacccatagg aacgtaatcg gtaaccgatg
    10861 acaaaaatag tataccacaa tatatttaga tcatcaaggt cacttaattc ttgaaatata
    10921 gggtctaggc gacaaagtct ttaaaatcag aaaaacgcat aatatcaggt gtgcaaaaac
    10981 ttgatactat gcgttttatt gtgggaaggt ttactccatt ttctcctgaa attgagtttt
    11041 tgtccagcct ctgtttttag aattgctaag aaaataatgt catgtggtga atatttgtaa
    11101 atcagtcagc agacagaacg aatactcttc gaaaatctct tcacatcatg tcagcttcgt
    11161 cttgccgtgt ccatggggga cttgacttga tcagttttca aatctgtact ttgagcaagc
    11221 tgagactagc ttcctatttg attttcattg aatatcagaa acccattctc catcaaataa
    11281 ttcgactgcg tctaataatt tttggtctgg caaggtgtca gaaataaagg ttgtgtattt
    11341 ggagagggga ttaattttaa aaaatccagt cttgtaaaat ttagaactat caatcagtaa
    11401 gatggtttca tgggctttgt caataatatt cttttttgaa atagcttggc tgagagaagc
    11461 ttcataaaca tattggtcat caatacctct tgctgaacaa aatgctaaat cgatattaaa
    11521 atgatctaat aaagaatttt ccttatcata gttgaccacg gaacaggatt gatgtttgac
    11581 ctcgccagat gtgataaaga ttttggagct atctttaaca gtttcagata gggtttgtgc
    11641 agtatgtaaa ccatttgtaa aaataatcaa attatcaagt tcagaaagat agggacaaag
    11701 ttcgtagaca gtagtactag aatctagata gatacacata ccagaccgaa taaagtcttt
    11761 agcgagacta gcgattagtc ttttttgcct agtactttct ccttcccgta tttgatgaga
    11821 aagttcaatt gtgttcatag aggacagggt cacgtatccg tgctttcttt tgataagacc
    11881 ttgattttct aagaaaatta aatcacgacg taaggtactt gtgctggaga aagtgatttc
    11941 tgccagctct tttacggcaa ttcttttttt ctttttaata atttcaatca attcaagtac
    12001 acgttcatct tttatcataa gctcctccta atttatcatt tcaactatat tatagcacaa
    12061 attggaggaa tttgaattat ttttatgaat attgggttaa catttgaaca ttattcaagt
    12121 aagcgttcac atattgaaaa aataaaacgt ggggattata ataaagttaa tcaaggacga
    12181 agagagaaga aaaatggaag cggttttagc aatagattta ggtgcgactt ctggaagagc
    12241 aatcgttggt tacctttctg aaaataaact agtaatggaa gaaataaatc gcttttctaa
    12301 tctacctatt agagtaaaag ggcatttatc ttgggatatt gactttctac tagctaaaat
    12361 tcttgaaagt atccgcttgg ctaatactag ttacaagatt ttatctatcg gtattgacac
    12421 atggggagtt gattttggac tgattgataa tgaaggtaag ctgttatcac aacctgttca
    12481 ttatcgtgat gaaagaacaa agggagtgtt aaaggaaata tctgaaatga ctgaattaga
    12541 aaaactgtat tcagagacag gaaatcagat tatggagata aataccttgt ttcaactctt
    12601 taaggcacgt caagaatctc ctgactcttt ctataagacc aataagattc ttttaatgcc
    12661 agatttgttt aattatctct tgacaggtaa gtttgctaca gaaaaaagca ttgcttcaac
    12721 aactcaatta tttgatccta ggagtcaaaa ttggaatcag aatatcttaa aactatttga
    12781 attggattca tctttacttc ctgaaattgt ttcagaggga aatgttcttg gaaggataaa
    12841 aaaggagtat ggtttaggcg atattcctgt tgtgaatgtt tgtagtcatg atacagcaag
    12901 tgcgattgtc tcagtaccta agacagaagg tagtttattt atttcatcag gtacttggtc
    12961 tttggttgga gtggaactta cttcaccgat tcttactacc gaatccttca gttatggatt
    13021 tacaaatgaa gtcggtaaag atggagtgat tacatttctg aagaattgta cagggttgtg
    13081 gatcatagag gaactaagac gttcatttga acgaagaggg aaagcctatt cttttgatga
    13141 tattaggaca atggtggaga aagaaaaaga aaatcttcct ctgattgata ctgaatcaac
    13201 tgaatttgca acagaatctg atatgcacaa gactttgaca gaatatctag cttatcatca
    13261 tgaaactaga gagtggacag atggacaact atttaagatt gtttatgaaa gcctagctga
    13321 aacgtatagg aaagcgatag agttattaga agaactaact cataaggttt ataagaggat
    13381 atatgtgatt ggaggaggtg ctagagccag ttattttaac caaatgattg ctgatagaac
    13441 tggtaaagag gttcttacag gtttgactga ggctacagct gtggggaata ttgttgtgca
    13501 gctcatagct atgggacaat taaaagggat ggaagaggct caccatgtta ttgaggagtt
    13561 tctacaatta gagagttatt actcccaaaa gaattaaaaa gattgagagt ttgtaaattt
    13621 gcctccctcc cccttcttag cttttgtgca ggaagggggg ataattggtg aattgaaaaa
    13681 tatttagtgt tttgatatga ggaggacaag gatgtcagat gtaaaacaag aattaattaa
    13741 atatggtaag aagctagtag aaacagattt gacgaaagga acaggtggga atctcagcgt
    13801 tttcgatcgt gaaaaacaat tgatggcaat taccccgtcg ggtattgatt tctttgaaat
    13861 caaagaatcc gatattgtag tgatggatat taatggaaat gttgtagagg gagaacgctt
    13921 gccatctagc gaatggtata tgcatttgat tcaatatcaa actcgtgatg atatcgatgc
    13981 aattatccat gctcatacaa cttatgcaac agtattagct tgtctcagag aaccacttcc
    14041 agcgagtcat tatatgattg cagtggcagg gaaagatgtt cgggtagctg agtatgcaac
    14101 atatggcacg aaagaattgg ctgtgaatgc agctaaagca atggaaggtc gtagagcagt
    14161 tttactagcg aatcatggaa ttttagcagg tgcacaaaat ttattgaatg catttaatat
    14221 tgttgaagaa gttgaatatt gtgcaaaaat ttattgttta gctaagaatt ttggagagcc
    14281 agtagttctt cctgatgagg agatggaatt gatggcagaa aaatttaaaa catacggtca
    14341 gagaaaatag ggaggatatt aatgttaaaa catataccga aaaatatttc tccagattta
    14401 ttgaagactt taatggaaat gggacatgga gatgaaatag tattagctga cgcgaattat
    14461 ccttctgcct catgtgcaaa taagctaatt cgttgtgatg gcgtaaatat tccagaatta
    14521 ttagattcca ttctgtattt aatgccatta gatagttacg tcgatagttc aattcagttt
    14581 atgaacgttg tttcgggtga tgatattcct aagatatggg gtacctatag acagatgatt
    14641 gaaggtcatg gtacagatct taaaacgatt acttatctta gaagagaaga cttttatgaa
    14701 cgtagtaaga aagcttatgc tattgttgct acaggagaaa cttcacttta tgctaatatt
    14761 atccttaaga aaggagtagt tgttgaaaga gaaaatgttt aatagaggaa ttttagttgc
    14821 cagtcatggt gattttgcta gcggagctct catgaccgca gaaatgtttg ttggtgagac
    14881 aacaaatgat agagttagga cattaggttt gatgcctgga gagaatattg tagagtttga
    14941 gcattatttt aaaaatcaag tggatgaact gttagactca aatcaagagg ttatcgtttt
    15001 gactgacttg attggaggaa gtcctaataa tgtggctttg tcacggtttt taaatttgga
    15061 ttcagttgat attgtaacag ggtttaatat tcctctccta gtggaattaa tatcaaatta
    15121 tgattcaaaa atcaatttag aagaaattgt tcacaatgct caaaatagtt tgtttaatgt
    15181 taaacaacaa cttaacgtag aggaggaaga aaatttatgt ctatagagtt tgttcgtatt
    15241 gatgaccgtc tggtacatgg tcaagttgtc actacgtggc taaaaaagta tgatattgag
    15301 caagttatca ttgttaatga tcgcatctca gaagataaaa cacgacaatc tattttaaag
    15361 atttctgcac cagtaggttt aaaaattgtt ttctttagtg taaaacggtt tgtggaagtt
    15421 ttaaactctg tgccaataaa aaagagaaca atgctgatat atacaaatcc aaaagatgtg
    15481 tatgattcta ttgaaggaaa tttaaaattg gagtacctca atgtaggaca gatgagtaaa
    15541 acggaggaaa atgaaaaggt aacgggaggt gtagctctag gtgaagaaga caaatattat
    15601 tttaagaaaa tagttgataa gggaacgaga gttgaaattc aaatggttcc taatgataaa
    15661 gttacaatgt tggaaaaatt tttataaaaa taatttaagg aggtacagta tatgctattc
    15721 acacaagcat tactggtgac attagttggg attattgcca ctattgacta taatggaccg
    15781 ttatttatga ttcaccgtcc gttagttaca agtgcaatgg ttggcttagt cttaggagat
    15841 ttcacccaag gtgttcttat tggttcagct cttgaattaa cttggctcgg tgtaacaggt
    15901 attggaggtt acactccacc agatactatt tcaggtgcga ttattggtac tgcatttggt
    15961 attttatctg gtcaaggaga aactgctggt atcgctatag cagttccaat tgcagttgct
    16021 acccaacagt tggatgttct tgcaaaaact ttagatgttt attttgtgaa aaaagctgat
    16081 aatgatgcta aaaacggaga ttattcaaag atcggttttt atcattattc aagtttggtt
    16141 ttaatcacgt tatttaaaat tgtaccaatt ttcctagcta ttatgcttgg aggggaatat
    16201 gtggcagact tgtttgctaa ggttccacca atcgttatgc agggacttaa ctctgcaggt
    16261 gctttactac cttcaattgg ttttggtatg cttttaaata tgatgctcaa gaaaaatatg
    16321 tgggtattct tgttgattgg attcatttgt tctgtgtatg gaggaatgtc aaccattggg
    16381 atctcactag ttggtattgc ggtagcatac ttctacgata tgattggaag taaaccacaa
    16441 gaaacaactt caagtagtga tgttgaggag gatcttgatc tatgatgaat aataaagtaa
    16501 ctaaagttga acttaaaaaa gttttcaaac gaagttttat gtatggttct tcatggaact
    16561 atgagagaat gcagaaccta ggttttctat atacaattct tccagtattg aaaaaactat
    16621 acccagacaa agattcagct tctcctgcaa tgaaacgtca ccttgagttt ttcaatactc
    16681 atcaaacagc ggcaccattt attcttggag ttacttccgc tatggaagaa caagaaggaa
    16741 atgaaggtgc agcttcaatt actggtatta aagttggctt gatggggcca ctggctggtc
    16801 taggagatag tttgttctgg ctgacactag ttcctatctg ttttagtatt ggtgcgtctt
    16861 attctaaaga cggcggtgct ttaggtatct ttatcgcctt aatattgttt aatattatta
    16921 atattcctgt taaatatttc ggtttgaaat atgggtatac taagggttct agtcttatcc
    16981 aagaaaataa tacaaaagga acattgaatc gcgttacgag tatggcgaca gcattagggc
    17041 tagtactagt gggtggtttg attccatcaa tggttggtat taattttgga ttagaattta
    17101 agcaggggga acttgttatt tctgttcaag aaatgattac aaaattaatt ccaggattta
    17161 tccctatggc tttgacttta ttaatgtgta aattaattag aaaaggaaag aatccggttg
    17221 tactaatctt tagtgttatg gctattggag ttatcctagt tgttttagga attttgaagt
    17281 agtagaaagt gtggaggtgg tatttgggat atcacctcca ttttggaaga gaggtaaaga
    17341 gtgaaattat ggtataagaa agctgcctca aattggaatg aagccttgcc gattgggaac
    17401 ggtcatttag gtggtatgat ttatggttca gctacaaaag aatgtattca actaaacgat
    17461 gagactattt ggtatagagg aaagtcagat agaaataatc cagactcact attgcatctt
    17521 aaaaaaattc gggaatatct tttagatgga gaaattcaga aagccgaaga attgataaag
    17581 ttaacaatgt ttgctacccc aagagatcaa agccactatg aattacttgg ggaactttac
    17641 attgagcata tagatattca gtcttgtgct ctttcattgt atgaaagaga gctagattta
    17701 gatacagcta tttctaatgt tgtgtttgag cctaatagtt gtaatttaca aataaaaaga
    17761 gaatatttta cgagttttaa taagaatatt ttatgttgcc gtatagtgtc atcagttcaa
    17821 aacacattaa atttaaacat taatttgggt agaaataaac ggtttaatga cgaagtatct
    17881 aaactggatt caagtacaat tttaatgtcg gcctctgctg gaggtagaaa aggtgttcag
    17941 tttaaagtag tatgtcattc taaagttacg gatggtgaag taagtgtatt gggagagaca
    18001 atagttattc ggaatgctac agaggtattt ctttatctca aatcaatgac ggattattgg
    18061 ggaaatatag atatttcttc tcttcaggga gaatttagta gtattgatta ctttacagaa
    18121 aaagatgaac atgtaaaaaa atatcaggag caatttaata gagttgattt taaactagac
    18181 tatagtaaag attgtcttag cattccaacg aatctacttc ttgaaaacac taaaaagtat
    18241 agtaactact tgactaactt gttatttcat tatggaagat atctgttaat atcgtctagt
    18301 caaccgaatg gtttacctgt caatcttcaa ggaatatggt gtgatgaatt aaatccaatt
    18361 tggggttcta aatatacgat taatattaat actcaaatga attattggat ggtaggtcca
    18421 tgtgatttac cagaagtaga atatccatta tttgatatgc tcgaaagaat gagagaaccg
    18481 ggaagactaa ccgctaagaa aatgtatgga gctagaggtt ttacagcaca tcataatacg
    18541 gatggttttg gcgatacggc tccccaatct catgccatgg gggctgcaat ttgggtatta
    18601 actattccat ggttatgtac tcatatttgg gaacactatt tatatttcca agatgagcgt
    18661 attcttacgg aacattttga aatgataaaa gaagcatttc ttttctttga agattattta
    18721 tttgaggtgg atggctactt gatgacaggt ccaagtgtct caccggaaaa taaatatcgc
    18781 ttaaaaaatg gtattgaagg aaatgcttgt ctatcatcta caattgataa tcaaattcta
    18841 agatattttt gtgattcatg cattggcatt gcaaaacaat taggagacaa ttcggatttt
    18901 attagtcgtg tgaaggagtt aaaaaagaaa ctacctaaaa caaaaatagg tagtaatggg
    18961 caaatccaag aatggttaga agattatgaa gaagtagagc ctgggcatag acacatttca
    19021 cctctatttg ggctttatcc ttataatgag attgatattc ataaaactcc ggaattagca
    19081 gaagcagcta aaatcactat caataggaga ttatcaaacg ctaacttttt atcttcacag
    19141 gagagggagc aagcgattaa taattggtta gtaagtggtt tgcatgctag tacacaaaca
    19201 ggttggagtg ctgcatggct gattcatttt tttgcgagac tatatcaagg tgaacctgct
    19261 tataaccaga ttaatggttt gttaaataat gcgactcttg gcaatttatt tcttgaccat
    19321 ccaccatttc aaattgatgg taatttaggt ttggtgagtg gaatttgtga attattagta
    19381 cagagccatc ataattggtt atcactaatt ccagctttac cttctgcttg gtcagaagga
    19441 gaagtgaaag gtttcagagt aagaggagga tataaggtat cgtttgcttg gaaaaatggg
    19501 gatataacat tcctaaaatt ggaaggagga aacaaagatc aaaaagtaag agtaagaata
    19561 tatggcaaaa atactgatgt acaaaatatt gaattggtat ttaattcaga aaaaattatt
    19621 gagttaaatt tttaggtata agtcatgaat aaagaaaaaa taaaaagaaa attaatcaca
    19681 atactgtttg tatgtattgg gatgttatgt tttggattgt tagcaggagt taaggctgat
    19741 aatcgtgttc aaatgagaac gacgattaat aatgaatcgc cattgttgct ttctccgttg
    19801 tatggcaatg ataatggtaa cggattatgg tgggggaaca cattgaaggg agcatgggaa
    19861 gctattcctg aagatgtaaa accatatgca gcgattgaac ttcatcctgc aaaagtctgt
    19921 aaaccaacaa gttgtattcc acgagatacg aaagaattga gagaatggta tgtcaagatg
    19981 ttggaggaag ctcaaagtct aaacattcca gttttcttgg ttattatgtc ggctggagag
    20041 cgtaatacag ttcctccaga gtggttagat gaacaattcc aaaagtatag tgtgttaaaa
    20101 ggtgttttaa atattgagaa ttattggatt tacaataacc agttagctcc gcatagtgct
    20161 aaatatttgg aagtttgtgc caaatatgga gcgcatttta tctggcatga tcatgaaaaa
    20221 tggttctggg aaactattat gaatgatccg acattctttg aagcgagtca aaaatatcat
    20281 aaaaatttgg tgttggcaac taaaaatacg ccaataagag atgatgcggg tacagattct
    20341 atcgttagtg gattttggtt gagtggctta tgtgataact ggggctcatc aacagataca
    20401 tggaaatggt gggaaaaaca ttatacaaac acatttgaaa ctggaagagc tagggatatg
    20461 agatcctatg catcggaacc agaatcaatg attgctatgg aaatgatgaa tgtatatact
    20521 gggggaggca cagtttataa ttttgaatgt gccgcgtata catttatgac aaatgatgta
    20581 ccaactccag catttactaa aggtattatt cctttcttta gacatgctat acaaaatcca
    20641 gctccaagta aggaagaagt tgtaaataga acaaaagctg tattttggaa tggagaaggt
    20701 aggattagtt cattaaacgg attttatcaa ggactttatt cgaatgatga aacaatgcct
    20761 ttatataata atgggagata tcatattctt cctgtaatac atgagaaaat tgataaggaa
    20821 aagatttcat ctatattccc taatgcaaaa attttgacta aaaatagtga ggaattgtct
    20881 agtaaagtca actatttaaa ctcgctttat ccaaaacttt atgaaggaga tgggtatgct
    20941 cagcgtgtag gtaattcctg gtatatttat aatagtaatg ctaatatcaa taaaaatcag
    21001 caagtaatgt tgcctatgta tactaataat acaaagtcgt tatcgttaga tttgacgcca
    21061 catacttacg ctgttgttaa agaaaatcca aataatttac at
//
LOCUS       DAVBEO010000039        20838 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 009
            SAMEA1678075-rid20185393.denovo.039, whole genome shotgun sequence.
ACCESSION   DAVBEO010000039 DAVBEO010000000
VERSION     DAVBEO010000039.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678075
            Sequence Read Archive: ERR226392
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 20838)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20838)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980207.1
            Genome Coverage       :: 150x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:50:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 72 of 147
            Pseudo Genes (incomplete)         :: 72 of 147
            Pseudo Genes (internal stop)      :: 42 of 147
            Pseudo Genes (multiple problems)  :: 32 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20838
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678075-rid20185393.denovo.039"
                     /strain="KS 009"
                     /db_xref="taxon:1313"
     gene            182..658
                     /locus_tag="VQ543_001473"
     CDS             182..658
                     /locus_tag="VQ543_001473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET2612182.1"
                     /translation="MKLSLYSEVEHYHFLSSYSLNDITYTDTPKNIIEKSKKDKYRYP
                     IVILNKDHKVIGFFCLHLNTGPKEYGYYQNDYALIRGFSIHDNFRNQGYGSNALNEIF
                     EFIDSTLKLEINHIILAVNEKNILAQKAYRNSGFSVVKKDLEGKRGKLIIMEKSRN"
     gene            complement(1332..1724)
                     /locus_tag="VQ543_001474"
     CDS             complement(1332..1724)
                     /locus_tag="VQ543_001474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComGF"
                     /protein_id="HET2612183.1"
                     /translation="MWKKKKVKAGVLLYAVTIAAIFSLLLQFYLTRQIAHYQDYALNK
                     EKLVAFAMAKRTKDKAEQESGEQVFNLGQVSYQNKKTSLVTTVRTDKSQYEFLFPSVK
                     IKEEKTDKKEEVATDSSEKAEKKIRREA"
     gene            complement(1702..2163)
                     /locus_tag="VQ543_001475"
     CDS             complement(1702..2163)
                     /locus_tag="VQ543_001475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000250539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComGF"
                     /protein_id="HET2612184.1"
                     /translation="MVQNSCWQSKSHKVKAFTLLESLLALIVISGGLLLFQAMSQLLI
                     SEVRYQQQSEQKEWLLFVGQLEAELDRSQFEKVEGNRLYMKQDDKDIAIGKSKSDDFR
                     KTDASGRGYQPMVYGLKSAQITEDNQLVHFRFQFQKGLEREFIYRVEKEES"
     gene            complement(2126..2386)
                     /locus_tag="VQ543_001476"
     CDS             complement(2126..2386)
                     /locus_tag="VQ543_001476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000601743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2612185.1"
                     /translation="MILLEAVVALAIFASIATLLLGQIQKNRQEEAKILQKEEVLRVA
                     KMALQTGQNQVSINGVEIQVFSSEKGLEVYHGSEQLLAIKEP"
     gene            complement(2391..2819)
                     /locus_tag="VQ543_001477"
     CDS             complement(2391..2819)
                     /locus_tag="VQ543_001477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012386909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system protein"
                     /protein_id="HET2612186.1"
                     /translation="MEGQIVKSMIKAFTMLESLLVLGLVSILALGLSGSVQSTFAAVE
                     EQIFFMEFEELYRETQKRSVASQQKTSLNLDGQMISNGSQKLTVPKGIQAPSGQSITF
                     DRAGGNSSLAKVEFQTSKGAIRYQLYLGNGKIKRIKETKN"
     gene            complement(2788..3114)
                     /locus_tag="VQ543_001478"
     CDS             complement(2788..3114)
                     /locus_tag="VQ543_001478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin-type N-terminal cleavage/methylation
                     domain-containing protein"
                     /protein_id="HET2612187.1"
                     /translation="MKKMMTFLKKAKVKAFTLVEMLVVLLIISVLFLLFVPNLTKQKE
                     AVNDKGKAAVVKVVESQAELYSLDKNEDATLSKLQGDGRITEEQVKAYNEYYTKNGGA
                     NRKVND"
     gene            complement(3116..4132)
                     /locus_tag="VQ543_001479"
     CDS             complement(3116..4132)
                     /locus_tag="VQ543_001479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000355375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system F family protein"
                     /protein_id="HET2612188.1"
                     /translation="MDISQVFRLRRKKLATAKQKNIITLFNNLFSSGFHLVETISFLD
                     RSSLLDKQCVTQMRTGLSQGKSFSEMMESLGCSSTIVTQLSLAEVHGNLHLSLGKIEE
                     YLDNLAKVKKKLIEVATYPLILLDFLLLIMLGLRNYLLPQLDSSNIATRIIGNLPQIF
                     LGMVGLVSVLALLALTFYKRSSKMSVFSILARLPFIGIFVQTYLTAYYAREWGNMISQ
                     GMELTQIFQMMQEQGSQLFKEIGQDLAQTLKNGREFSQTIGTYPFFRKELSLIIEYGE
                     VKSKLGSELEIYAEKTWEAFFTRVNRTMNLVQPLVFIFVALIIVLLYAAMLMPMYQNM
                     EVNF"
     gene            complement(4080..5021)
                     /locus_tag="VQ543_001480"
     CDS             complement(4080..5021)
                     /locus_tag="VQ543_001480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000249584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II/IV secretion system protein"
                     /protein_id="HET2612189.1"
                     /translation="MVQEIAQEIIRSARKKGTQDIYFVPKLDAYELHMRVGDERCKIG
                     SYDFEKFAAVISHFKFVAGMNVGEKRRSQLGSCDYAYDQKMASLRLSTVGDYRGHESL
                     VIRLLHDEEQDLHFWFQDIEELGKQYRQRGLYLFAGPVGSGKTTLMHELSKSLFKGQQ
                     VMSIEDPVEIKQDDMLQLQLNEAIGLTYENLIKLSLRHRPDLLIIGEIRDSETARAVV
                     RASLTGATVFSTIHAKSIRGVYERLLELGVSEEELAVVLQGVCYQRLIGGGGIVDFAN
                     RDYQEHQAAKWNEQIDQLLKDGHITSLQAETEKISYS"
     gene            complement(5097..5462)
                     /locus_tag="VQ543_001481"
     CDS             complement(5097..5462)
                     /locus_tag="VQ543_001481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1033 family protein"
                     /protein_id="HET2612190.1"
                     /translation="MYRVIEMYGDFEPWWFLEGWEEDIVASRKFDQYYDALKYYKTCW
                     FRLEQESPLYKSRSDLMTIFWDPEDQRWCDECDEYLQQYHSLALLQDEQVIPDEKLRS
                     GYEKQTSQERNRSCRMKLK"
     gene            complement(5613..6671)
                     /locus_tag="VQ543_001482"
     CDS             complement(5613..6671)
                     /locus_tag="VQ543_001482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-dependent alcohol dehydrogenase family
                     protein"
                     /protein_id="HET2612191.1"
                     /translation="MKAYTYVKPGLASFVDVDKPVIRKPTDAIVRIVKTTICGTDLHI
                     IKGDVPTCQSGTILGHEGIGIVEEVGEGVSNFKKGDKVLISCVCACGKCYYCKKGIYA
                     HCEDEGGWIFGHLIDGMQAEYLRVPHADNTLYHTPEDLSDEALVMLSDILPTGYEIGV
                     LKGKVEPGCSVAIIGSGPVGLAALLTAQFYSPAKLIMVDLDDNRLETALSFGATHKVN
                     SSDPKKAIKEIYDLTDGRGVDVAIEAVGIPETFDFCQKIIGVDGTVANCGVHGKPVEF
                     DLDKLWIRNINVTTGLVSTNTTPQLLKALESHKIEPEKLVTHYFKLSEIEKAYEVFSK
                     AADHHAIKVIIENDISEA"
     gene            complement(6834..7985)
                     /gene="nagA"
                     /locus_tag="VQ543_001483"
     CDS             complement(6834..7985)
                     /gene="nagA"
                     /locus_tag="VQ543_001483"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HET2612192.1"
                     /translation="MPNYIKADQFFYPHGVRRGGYLELVDGKFGKHVEQIPEGAEVID
                     YTGYSIAPGLVDTHIHGYAGVDVMDNNIEGTLHTMSEGLLSTGVTSFLPTTLTATYEQ
                     LLAVTENLGNHYKEATGAKIRGIYYEGPYFTETFKGAQNPTYMRDPGVEEFHSWQKAA
                     NGLLNKIALAPERDGVEDFVRTVTGEGVTVALGHSNATFDEAKKAVDAGASVWVHAYN
                     GMRGLTHRELGMVGAMYQLPHTYAELICDGHHVDPKACEILIKQKGTENIALITDCMT
                     AGGLEDGDYMLGEFPVVVANGTARLKSTGNLAGSILKLKDGLKNVVEWGIANPHEAVM
                     MASFNPAKSVHIDDVCGQIREGYDADFIVLDKDLELVATYLDGVKRYQA"
     gene            complement(8138..9955)
                     /locus_tag="VQ543_001484"
     CDS             complement(8138..9955)
                     /locus_tag="VQ543_001484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001220923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HET2612193.1"
                     /translation="MRIKWFSLIRIIGLLLVLLYHFFQTIFPGGFFGVDVFFTFSGFL
                     ITALLIEEFSKNNEIDLIGFFRRRFYRIVPPVVLMVLVTMPFTFLVRQDYVAGIGGQI
                     AGVLGFMTNFYELLTGGSYESQFIPHLFVHNWSLAVEVHYYILWGLAVWFLSKQAKSN
                     GQLKGMIFLLSATAFLISFFSMFIGSFLVTSYSSVYFSSLTHVYPFFLGSMLATIVGV
                     RQTTSLVKQLDKIWDLRKTLVVFGGGFGFLVLLTFFVKFTYLFAYLIGFLLASLAALA
                     MILAARVLHEKTHHIQEPKIISFLADTSYAVYLFHWPFYIIFSQLTSNLLAVLLTLIC
                     SYGFASLSFYVLEPWIAGKNTPILQTLRPLPYIHAILAAGTGILTFIVCMVTLLAPQV
                     GAFETDLTVNGLKQAATNIGQTKVMAERADANSLGIADGTMLIGDSVALRANTALQTA
                     LPGAQINAQVSVTTKTANEIMLNNSQNKFLPKTVVIATGVNNPENYKDDWDSIVKNLP
                     KGHHMILVTPYEGDKTKETYAIVEKAAAYMRELAEKTPYITIADWNQVAKEHPEIWAG
                     TDQVHFGSESSTIEAGAKLYADTIATALQTAQDKPVKSK"
     gene            complement(10056..11198)
                     /gene="tgt"
                     /locus_tag="VQ543_001485"
     CDS             complement(10056..11198)
                     /gene="tgt"
                     /locus_tag="VQ543_001485"
                     /EC_number="2.4.2.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004298827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA guanosine(34) transglycosylase Tgt"
                     /protein_id="HET2612194.1"
                     /translation="MSDSPIKYRLIKKEKHTGARLGEIITPHGTFPTPMFMPVGTQAT
                     VKTQSPEELKEMGSGIILSNTYHLWLRPGDELIARAGGLHKFMNWDQPILTDSGGFQV
                     YSLADSRNITEEGVTFKNHLNGSKMLLSPEKAISIQNNLGSDIMMSFDECPQFYQPYD
                     YVKKSIERTSRWAECGLKAHRRPHDQGLFGIVQGAGFEDLRRQSAHDLVSMDFSGYSI
                     GGLAVGETHEEMNAVLDFTTQLLPENKPRYLMGVGAPDSLIDGVIRGVDMFDCVLPTR
                     IARNGTCMTSQGRLVVKNAQFAEDFTPLDPECDCYTCNNYTRAYLRHLLKADETFGIR
                     LTSYHNLYFLLNLMKQVRQAIMDDNLLEFRKYFVEKYGYNKSGRNF"
     gene            11328..12185
                     /locus_tag="VQ543_001486"
     CDS             11328..12185
                     /locus_tag="VQ543_001486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HET2612195.1"
                     /translation="MNYPKIDLKTIRQESKHFQADTPRLFLLYILPSMLVILSGFLNP
                     LSRIHGTVLEQPFFSILGQILQTYLFPLLVSFIGTILLTSSVYATLTLMKDSKTEPSV
                     KNSLALFDEERFSQTFLTLLLKRFYLFLWSIPNLLGIYLLFYSSFLAKKFVTLHPEFP
                     NLDLSSVETERFLMVFGLYFLASLILIIVGNILYIPQYYAYSQVEFLLCYSLDLGQVP
                     PRRILKTSRSFMKGYKFQHFVLDLQLLPWYFLNWITFGIASFSLLPYIQCTKIMFYRA
                     VLARKRPKA"
     gene            complement(12213..12857)
                     /gene="pcp"
                     /locus_tag="VQ543_001487"
     CDS             complement(12213..12857)
                     /gene="pcp"
                     /locus_tag="VQ543_001487"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HET2612196.1"
                     /translation="MKVLVTGFEPFGGEKGNPTLEAIKGLPAEIHGAEVRWLEVPTVF
                     HKSAQVLEEEMNRYQPDFVLCIGQAGGRTSVTPERVAINQDDARISDNEDNQPIDRPI
                     RPDGASAYFSSLPIKAMVQAIKKEGLPASVSNTAGTFVCSHLMYQALYLVEKKFPYVK
                     AGFMHIPYMMEQVVNRPTTPTMSLVDIRRGIEAAIGAMIEHGDQELKLVGGETH"
     gene            complement(12964..13332)
                     /locus_tag="VQ543_001488"
     CDS             complement(12964..13332)
                     /locus_tag="VQ543_001488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1304 domain-containing protein"
                     /protein_id="HET2612197.1"
                     /translation="MSIITIILTTIVALEHFYIFYLESIATRSDATSRVFNMEKEELA
                     HPSVSSLFKNQGIYKALLGVFLWYGIYFSQNLEIVTIFVLFVIGAATYGSLTADKKII
                     LKQGGSAILALISILLFKYT"
     gene            complement(13343..13768)
                     /locus_tag="VQ543_001489"
     CDS             complement(13343..13768)
                     /locus_tag="VQ543_001489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000890080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HET2612198.1"
                     /translation="MIEIQDLLYQLRLSEQASTQLFEKRLGISLTRYQILLFLLEHSP
                     CNQMAVQERLKIDQAALTRHFKILETEGLVERHRNPENQREVLVEAAKYAKEQLVVNP
                     PLQHIKVKEEMESILTEFERTELSRLLNKLVLGIENIEI"
     gene            complement(14193..15335)
                     /locus_tag="VQ543_001490"
     CDS             complement(14193..15335)
                     /locus_tag="VQ543_001490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HET2612199.1"
                     /translation="MKKRMLLASTVALSFAPVLATQAEEVLWTARSVEQIQNDLTKTD
                     NKTSYTVQYGDTLSTIAEALGVDVTVLANLNKITNMDLIFPETVLTTTVNEAEEVTEV
                     EIQTPQADSSEEVTTATADLTTNQVTVDDQTVQVADLSQPIAEAPKEVASSSEVTKTV
                     IASEEVAPSTGTSVPEEQTAETSSAVAEEAPQGTTPAEKQETQASPQAASAVEATTTS
                     SEAKEVASSNGATAAVSTYQPEETKIISTTYEAPAAPDYAGLAVAKSENAGLQPQTAA
                     FKEEIANLFGITSFSGYRPGDSGDHGKGLAIDFMVPERSELGDKIAEYAIQNMASRGI
                     SYIIWKQRFYAPFDSKYGPANTWNPMPDRGSVTENHYDHVHVSMNG"
     gene            complement(15501..16121)
                     /locus_tag="VQ543_001491"
     CDS             complement(15501..16121)
                     /locus_tag="VQ543_001491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001172828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HET2612200.1"
                     /translation="MQKTAFIWDLDGTLLDSYEAILSGIEETFAQFSIPYDKEKVREF
                     IFKYSVQNLLVRVAEDRNLDVEVLNQVRAQSLAEKNAQVVLMPGAREVLAWADESGIQ
                     QFIYTHKGNNTFTILKDLGVESYFTEILTSQSGFVRKPSPEAATYLLDKYQLNSDNTY
                     YIGDRTLDVEFAQNSGIQSINFLESTYEGNHRIQALADISRIFETK"
     gene            complement(16125..17405)
                     /locus_tag="VQ543_001492"
     CDS             complement(16125..17405)
                     /locus_tag="VQ543_001492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000473957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HET2612201.1"
                     /translation="MFKKNKDILNIALPAMGENFLQMLMGMVDSYLVAHLGLIAISGV
                     SVAGNIITIYQAIFIALGAAISSVISKSIGQKDQSKLAYHVTEALKITLLLSFLLGFL
                     SIFAGKEMIGLLGTERDVAESGGLYLSLVGGSIVLLGLMTSLGALIRATHNPRLPLYV
                     SFLSNALNILFSSLAIFVLDMGIAGVAWGTILSRLVGLVILWSQLKLPYGKLTFGLDK
                     ELLTLALPAAGERLMMRAGDVVIIALVVSFGTEAVAGNAIGEVLTQFNYMPAFGVATA
                     TVMLLARAVGEDDWKRVASLSKQTFWLSLFLMLPLSFSIYVLGVPLTHLYTTDSLAVE
                     ASVLVTLFSLLGTPMTTGTVIYTAVWQGLGNARLPFYATSIGMWCIRIGTGYLMGIVL
                     GWGLPGIWAGSLLDNGFRWLFLRYRYQRYMSLKG"
     gene            complement(17466..18950)
                     /locus_tag="VQ543_001493"
     CDS             complement(17466..18950)
                     /locus_tag="VQ543_001493"
                     /EC_number="4.2.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006595200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine synthase"
                     /protein_id="HET2612202.1"
                     /translation="MTLVYQSTRDANNTVTASQAILQGLATDGGLFTPVTYPKVDLDF
                     DKLKDASYQEVAKLVLSAFLDDFTAEELDYCINNAYDSKFDTPAIAPLVKLDGQYNLE
                     LFHGSTIAFKDMALSILPYFMTTAAKKHGLENKIVILTATSGDTGKAAMAGFADVPGT
                     EIIVFYPKGGVSKVQELQMTTQNGDNTHVIAIDGNFDDAQTNVKHMFNDVALREKLTT
                     NKLQFSSANSMNIGRLVPQIVYYVYAYAQLVKTGEIVAGEKVNFTVPTGNFGNILAAF
                     YAKQIGLPVGKLICASNDNNVLTDFFKTRVYDKKREFKVTTSPSMDILVSSNLERLIF
                     HLLGNNAEKTAELMNALNTQGQYKLTDFDAEILDLFAAEYATEEETAAEIKRVYESDS
                     YIEDPHTAVASAVYRKYQAVTGDVTKTVIASTASPYKFPVVAVEAVTGKAGLTDFEAL
                     AQLHEISGVAVPPAVDGLEIAPIRHKTTVAAADMQAAVEAYLGL"
     gene            complement(19026..20303)
                     /locus_tag="VQ543_001494"
     CDS             complement(19026..20303)
                     /locus_tag="VQ543_001494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001277926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamylcysteine synthetase"
                     /protein_id="HET2612203.1"
                     /translation="MSCSIDLLKHRYLKNIKENPELFVGIELEYPVASLEGDATDVEV
                     IKDLFHYLVSTLDLTVAKVDDFGNLIQLVDPISQDAILFEVSYTTIEFAFGKAETIQE
                     VENRFNNYMNVIQRKLAESNHAIVGCGIHPNWDKNENCPVAYPRYQMLMDYLNLSRNI
                     IKSDLHHFPEYGTFICGSQVQLDISKTNYLRVINAFTQIEAAKAYLFSNSEFSGADWD
                     TKISRDIFWEESMHGIYPENVGVNARLLNDEADFFDYLNHSAIFTAERDGQTYYFYPI
                     QAGDYLATSEIQAFALNGDEVIIYPQEKDFETHRSYQYQDLTTRGTVEFRSVCTQPLD
                     RTFASAAFHLGLLVNLDKLEAYLETAPFFKVFGYDYKSLRRQFSKKNLTDEEETTIIE
                     FSKDLLLLAEEGLVVRNKEEMTYLQPLREELSL"
     gene            complement(20410..20493)
                     /locus_tag="VQ543_001495"
     tRNA            complement(20410..20493)
                     /locus_tag="VQ543_001495"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20457..20459),aa:Leu,seq:caa)
     gene            complement(20503..20574)
                     /locus_tag="VQ543_001496"
     tRNA            complement(20503..20574)
                     /locus_tag="VQ543_001496"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20540..20542),aa:Gln,seq:ttg)
     gene            complement(20588..20660)
                     /locus_tag="VQ543_001497"
     tRNA            complement(20588..20660)
                     /locus_tag="VQ543_001497"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20625..20627),aa:His,seq:gtg)
     gene            complement(20675..20745)
                     /locus_tag="VQ543_001498"
     tRNA            complement(20675..20745)
                     /locus_tag="VQ543_001498"
                     /product="tRNA-Trp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20711..20713),aa:Trp,seq:cca)
     gene            complement(20750..20830)
                     /locus_tag="VQ543_001499"
     tRNA            complement(20750..20830)
                     /locus_tag="VQ543_001499"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20794..20796),aa:Tyr,seq:gta)
BASE COUNT         6237 a         4734 c         3669 g         6198 t
ORIGIN      
        1 tggtattatc aatcatgaac taggattcta gttttgcagg aagtctaata atgaaaataa
       61 aggactaaag caataactct aaatacatct gatttttata ggatatttca taaaaaaaat
      121 ctacatacct agagtcctat ttagttatgt atcttacata aagagaaagg aattaattat
      181 catgaaatta tctttgtata gtgaagttga acattaccat tttttaagtt cttattcttt
      241 aaatgatatt acatatactg ataccccaaa aaatattatt gaaaagtcta aaaaagataa
      301 gtatagatac ccaatagtaa tacttaataa agaccataaa gtaattggat ttttttgcct
      361 acacctaaac actggtccta aagagtatgg ctattatcaa aatgattatg cgcttattag
      421 aggattttct attcatgata atttcagaaa tcaaggatat ggttctaatg ctctgaatga
      481 aatatttgaa ttcatagact caactttaaa attagaaatt aaccatatta tattggctgt
      541 aaatgaaaaa aatatattgg ctcaaaaagc atatagaaat tccggttttt ctgttgtgaa
      601 aaaagattta gaaggaaaaa gggggaaatt aattattatg gagaaaagca gaaactagta
      661 atgatactag tttctgcttt tctctaagtc tgctataaat ttataacatg ttgaaataag
      721 atgtgaataa attgattgca gaattcaaac caatttctaa caatgtttta gaaaactcgg
      781 cggactattc cagattcaat ccactatatt ctatcttatt tgcatatttt gagagaaata
      841 atctatatac taaactttta tgtttataat tcattccttt cgtttcactc aaggcacaag
      901 acagaatgaa aaagtggtgt gctctttatt ttgttttata ataatagtga gaaaacctat
      961 cactactaca aatcacgggg aggtgaataa gtgagtggta tagccactac ctcgcatttt
     1021 tataggtgtc attctttcca tcaagcacaa gaactgtgac taggagcacg taaacttata
     1081 attgaataag cgactcgttt gtgaaaggaa agaatagtca agggataggc agactcaaat
     1141 ttggtgaagg gaaacccctc atgttaaaag ccaaacttca attttaaaaa ttttaaaatt
     1201 tgtttcgtat tcactactcc ttgcctttat attggattga ttaagagaac ctttcgcgtt
     1261 tctagaaact acagtggact attctggatt caacgcatta tagttgaatt gactaggaat
     1321 tctctttctt ttcaggcttc tcttctgatt tttttctccg ctttttcgct tgaatcagtc
     1381 gctacctctt cctttttatc cgttttctct tctttgattt tgactgaagg aaacagaaac
     1441 tcatattgac tcttatccgt acgaacagtc gtcaccaagc ttgttttctt gttttgatag
     1501 ctcacctgac ctagattaaa aacctgttcc ccactttctt gctcggcttt atccttggtt
     1561 cgtttagcca tggcaaaagc aaccaatttt tctttattta aagcatagtc ttgatagtgg
     1621 gcgatttgtc gggtcaaata aaattgcaac aaaagactaa agatggctgc tatggtgact
     1681 gcgtagagga gaacacctgc cttaactttc ttctttttcc acacgataga tgaactccct
     1741 ttctaagcct ttttgaaact ggaaacgaaa atgaaccagt tgattgtcct ctgtaatctg
     1801 agctgatttg aggccataaa ccataggctg atacccccgt ccactagcat cggttttacg
     1861 aaaatcgtct gactttgact taccgatggc gatgtccttg tcatcttgct tcatgtatag
     1921 gcgattgcct tctacttttt cgaactgcga acggtctaat tctgcctcaa gttggcccac
     1981 aaacaagagc cactcctttt gctcgctttg ttgctggtag cgaacttctg aaatgaggag
     2041 ctgactcata gcttgaaaaa ggagtaatcc cccactgatg acaatgaggg caagcaggga
     2101 ttctaacaag gtaaaagcct tgaccttatg gctctttgat tgccaacaac tgttctgaac
     2161 catggtagac ctccaatccc ttttcactag aaaatacctg aatctcaact ccgttgatgc
     2221 ttacctgatt ttgccccgtc tgcaaggcca tcttagctac cctcaagact tcttcctttt
     2281 gcaagatttt tgcttcctct tgcctatttt tttgaatttg tcccaaaagg agggtcgcaa
     2341 tgctggcaaa gatagctaga gcgactactg cttccagtaa aatcactgcc ctaatttttt
     2401 gtttccttaa tgcgtttaat ttttccattt cctagatata attgatagcg aatcgctcct
     2461 ttactggtct gaaattcaac cttagccagg gacgaattgc ccccagctcg gtcaaatgta
     2521 atactttggc ctgatggtgc ctgaattcct ttaggaactg tcaacttttg actgccattg
     2581 ctaatcatct gcccatccaa gttcagacta gtcttttgtt gactagctac actgcgtttt
     2641 tgggtttccc gatagagttc ttcaaactcc ataaagaaaa tctgttcctc taccgctgca
     2701 aaagtggact ggacagagcc ggacaagccc aaggcaagga tactcacaag tcccaaaacc
     2761 aagagacttt ccagcatggt aaaggcctta atcattgact ttacgatttg cccctccatt
     2821 tttagtatag tattcattat aagctttaac ctgttcttcc gtgatgcgcc catctccttg
     2881 taacttgctc agagtagcat cttcattttt atccaagcta taaagttctg cctggctttc
     2941 caccacctta acaacagctg cttttccttt gtcattgact gcttcttttt gcttggtcag
     3001 attaggtaca aagagcaaga aaagcacgct gataatcagc aagaccacca acatctccac
     3061 caatgtaaaa gctttaacct tagctttttt caagaatgtc atcatttttt tcattttaaa
     3121 aatttacctc catattttga tacatgggca tgagcattgc cgcataaagt aaaacgataa
     3181 tcagtgccac aaagataaaa accagtggct gcaccaaatt catggtgcgg ttgactcggg
     3241 taaaaaaggc ttcccaagtt ttttcagcat agatttccaa ctcactaccc agcttggact
     3301 taacttcccc atactctatg atgagactca attccttcct aaagaaagga taggttccta
     3361 tcgtctgaga aaattcacgg ccatttttca gggtttgagc cagatcttga ccgatttctt
     3421 taaagagctg ggaaccttgt tcctgcatca tttgaaaaat ctgcgtcagc tccattccct
     3481 gtgaaatcat attcccccat tcacgtgcat aataggctgt caagtaggtc tgcacaaaga
     3541 ttccaataaa gggaaggcgt gctaagatag aaaagacact catcttagaa cttcttttat
     3601 aaaaagttag tgctaaaagg gcaagcacgg aaacaagccc taccatgcct agaaaaattt
     3661 gtggcagatt accgataatt cgggtggcaa tattgctact atccagttgt gggagcaggt
     3721 aattccgtag ccccagcata attaagagaa gaaaatccag caaaatcaaa ggataggtcg
     3781 ctacttcaat taactttttc ttgaccttgg ccagattgtc tagatattct tctatctttc
     3841 ccaaactcag gtgaagattg ccatgaactt cagctagaga taactgagtg acaatggtac
     3901 ttgaacatcc caaactttcc atcatttctg agaatgattt cccctgagac aagcctgtac
     3961 gcatctgggt cacacactgc ttgtccaaca aggaactcct atctaaaaag gagatagtct
     4021 ccaccagatg aaaaccgcta gaaaagagat tgttaaatag ggtgatgata tttttttgct
     4081 tagctgtagc taattttttc cgtctcagcc tgaagacttg tgatatgtcc atctttaaga
     4141 agttggtcaa tttgctcatt ccacttggct gcttggtgtt cttgataatc tctgtttgca
     4201 aagtcaacga ttcctcctcc cccgattaat ctctggtagc agactccttg cagaacaact
     4261 gccaattctt cttcactcac acccaactcc agcagacgct cataaacacc tcggatactc
     4321 ttggcgtgaa tggttgaaaa gactgtcgca cctgtcaaac tagctctgac cactgcacgc
     4381 gccgtctcgc tgtcacgaat ttctccgata atcaagagat ctggtcgatg acgcaaggaa
     4441 agtttgatta gattttcata ggttaggccg attgcttcgt tcaactgcaa ctgaagcatg
     4501 tcgtcctgct tgatttcgac aggatcttcg atggacataa cttgctgtcc tttaaagagt
     4561 gacttggaca attcatgcat caaggtcgtc ttaccactcc caaccgggcc agcaaaaaga
     4621 tagagtcccc gttgcctgta ctgcttgcct aattcttcaa tatcctgaaa ccaaaaatgc
     4681 aagtcctgct cctcatcgtg caacaaacgg ataaccaaac tctcatgccc ccgataatcg
     4741 cctacagtag ataaacgtag agacgccatc ttctggtcat aggcataatc acaggaaccc
     4801 agttgactac gtcttttttc tcccacattc atacccgcca caaacttaaa gtgactgata
     4861 acggctgcaa acttttcaaa atcatagcta ccaattttac agcgctcgtc tcctaccctc
     4921 atatgaagct cataggcgtc taacttaggg acaaaataaa tatcctgcgt cccttttttc
     4981 cgagctgaac gaatgatttc ttgtgcaatt tcttgaacca tacttacctc ctcacctata
     5041 ctattcgcaa agcgttagaa aaataaaaaa agcaactcca aaaaagttac ttttctctat
     5101 tttaatttca tacggcaaga acgattcctt tcctgactgg tttgtttttc atagcctgag
     5161 cgtagttttt cgtctgggat aacctgctca tcctgcaaaa gagccaaaga atggtattgt
     5221 tgtaaatact catcacattc atcacaccag cgttggtctt ccgggtccca aaaaatggtc
     5281 atcaagtcgc ttctactttt ataaagaggg gattcttgtt ccaatctaaa ccagcaagtt
     5341 ttgtagtatt tgagagcatc ataatactgg tcaaattttc tacttgctac aatatcttct
     5401 tcccaacctt ctaagaacca ccacggttca aaatctccgt acatttctat aacacgatac
     5461 atattcattc attcctttgt accgtatatt ataaccaatt ccgccagaca aggaaagaaa
     5521 tatgctcatt tcttaatttt ttgataaaaa atccagccat ctgatggatg actgaatttc
     5581 tatttgctta tgtacaaaaa tatttttact acttaggctt ctgagatatc gttttcgata
     5641 atgaccttaa tggcatggtg gtctgctgcc ttactgaaga cttcgtaggc tttttcaatt
     5701 tcactgagtt tgaaatagtg agttaccaat ttttccggtt caatcttatg actttcaagt
     5761 gctttcaaca attgtggagt cgtatttgta gataccaaac cagttgttac attgatgttg
     5821 cgaatccaaa gtttatctaa atcgaattca actggtttac catgcacacc acagttggca
     5881 accgttccgt ctacaccgat aatcttttga cagaaatcaa atgtttcagg aatccctaca
     5941 gcttcgatag cgacatccac accacgacca tctgtcaaat cataaatttc tttaatggct
     6001 tttttagggt ctgaagaatt aaccttatga gtcgcaccga atgatagggc agtttccaag
     6061 cggttatcgt ctaggtctac cataatcaat ttagctggtg aatagaattg ggctgttaaa
     6121 agagcagcca atccaactgg acctgaacca ataatggcta cgctgcaacc aggttctact
     6181 ttccctttta agacaccaat ttcatatcca gtaggcagaa tgtctgacag cataaccaaa
     6241 gcttcatctg acaagtcttc tggagtatgg taaagagtat tatctgcatg agggacacgt
     6301 agatattcag cctgcatacc atcaatcaag tgaccgaaaa tccagccccc ttcgtcttca
     6361 cagtgggcat aaattccttt tttacagtag tagcatttac cacaggcaca gacgcaagaa
     6421 atcaagacct tgtcaccttt tttgaagttg gaaactcctt ccccaacttc ttcaacaatc
     6481 ccaatccctt cgtggccaag aatggtacca ctttggcaag taggaacatc ccctttgata
     6541 atatggaggt ctgttccaca aatagtggtt tttacaatac gcacaatagc gtctgttggc
     6601 ttgcgaataa ctggtttgtc tacatcaaca aaagaagcaa gtcctggttt aacataagta
     6661 taggctttca taaagcactc ctccgttttt ttatttgtaa tatttatagt tcaattgtaa
     6721 gcctttttct ttgtttcttc aagctttttt tgtgattttt ttaacttttt atttaccagt
     6781 aaagtaccct gtataaaaaa gcagaagcta gtctctaact tctgccttct ctcttatgct
     6841 tgataacgtt tcacaccatc taggtaggtt gctaccaatt ccaaatcttt atctaatacg
     6901 atgaagtcag cgtcgtagcc ttcacggatt tggccacaga cgtcatcgat gtgaacggat
     6961 ttagctgggt tgaagctggc catcatgact gcttcatgcg gattcgcaat tccccattcg
     7021 accacattct tcaaaccatc tttgagtttg aggatagaac ctgccaagtt acctgtcgat
     7081 ttgaggcgtg cagttccatt tgcaacgaca actgggaatt ctcccaacat ataatctccg
     7141 tcttccaatc ccccagctgt catacagtct gtgataagag cgatgttttc tgttcctttt
     7201 tgtttgataa gaatttcgca agcctttgga tctacgtggt gaccatcaca gatcaactct
     7261 gcataggtat gtggcaattg gtacatggct ccaaccatac ccaattcacg gtgagtcaac
     7321 ccacgcattc cattgtaggc atgcacccaa acactcgctc cagcatcgac tgcttttttg
     7381 gcttcatcaa aagtcgcgtt tgaatgtcca agagcaaccg tcacaccttc gcccgtaact
     7441 gtacgaacaa agtcttccac cccatcacgt tctggtgcaa gggcaatttt attaagcaag
     7501 ccatttgccg ctttttgcca agaatgaaac tcctcaacac ccgggtctct catataagtt
     7561 ggattttgtg cccccttaaa agtttctgtg aaatatggac cttcataata aatcccacga
     7621 atcttagcac ctgttgcttc tttataatgg tttccaagat tttcagtgac tgcaagcaat
     7681 tgctcataag tggctgttaa agttgtgggt aagaaactgg taacaccggt actaagaagt
     7741 ccttcactca tagtatgcaa tgtaccttca atgttgttgt ccatcacatc tacacctgca
     7801 tatccatgaa tatgagtatc cacaagtcct ggggcaatgc tataacctgt atagtcaatc
     7861 acctcagccc cttcaggaat ctgctctaca tgtttcccaa acttgccgtc cacaagttcc
     7921 aagtaaccac ctcgacgaac tccgtgtggg tagaaaaact gatccgcttt aatatagtta
     7981 ggcataatgt taacctcctt aaaagattga ttctacaatt tattatgtca attacattat
     8041 aaacctttct tttttatttg taaatggtat agacctattt tttggagata ttttaaaaga
     8101 gctggatttc tccaactctt ctctttttta atacaagtta ttttgattta accggcttgt
     8161 cttgagctgt ctgcaaagct gtggcaatcg tatctgcata caattttgct cctgcttcga
     8221 tagtgctact ctcactcccg aaatgaacct ggtctgttcc agcccaaatt tctggatgct
     8281 ctttcgcaac ttgattccaa tctgctatcg taatgtaagg tgtcttctct gccaattctc
     8341 tcatataggc agcagccttc tcaacgatgg cataggtctc ttttgtctta tctccctcat
     8401 aaggagtcac caaaatcata tggtgtccct taggaagatt tttcacgata ctgtcccagt
     8461 catccttgta attctcagga ttatttaccc cagtcgcaat gaccaccgtc ttaggtaaaa
     8521 atttattctg gctattattt agcatgattt catttgcggt cttggttgtt acgctgacct
     8581 gcgcgttaat ctgtgctcca ggaagagctg tctgtagtgc tgtatttgcc cttaaagcca
     8641 ctgagtcacc aattaacata gtgccatcag caattcccaa actgtttgca tctgcccgtt
     8701 ctgccatcac cttggtctgg ccaatatttg ttgcagcttg cttcaagcca ttgacagtca
     8761 agtctgtctc aaacgctccc acttgtggtg ccaacaaggt caccatgcag acaatgaagg
     8821 tcaagattcc tgtacctgct gcaagaattg cgtgaatata aggcagggga cgaagagttt
     8881 gtaaaatagg tgtgttcttg cctgcaatcc aaggttccaa tacataaaat gacagactgg
     8941 caaagccata agaacaaatc agagtcagta atacagcaag aagatttgat gtcaactgtg
     9001 agaaaatgat atagaaaggc caatggaaaa gataaaccgc atagctagta tccgctaaaa
     9061 agctgataat cttcggctcc tgtatatgat gtgtcttttc atgtaagaca cgcgccgcca
     9121 gaatcatggc aagagctgca agactggcaa gcaagaagcc gataagatag gcaaaaagat
     9181 aagtgaattt gacaaagaaa gtcaaaagaa ctaggaaacc aaagcctcct ccaaaaacta
     9241 ctaaagtctt tcgtaaatcc cagattttat ccaactgctt gacgagggaa gtcgtctgac
     9301 gaacgcctac aatagttgct aacatacttc ccaaaaagaa tggatagaca tgagttaaac
     9361 tggagaaata aacagaggaa taagaggtca ctagaaaact accaataaac atggagaaga
     9421 aactgatcaa gaaggcagta gcagataaga gaaagatcat ccccttcaac tgaccatttg
     9481 atttagcttg tttggataag aaccaaactg ccaatcccca aagaatatag tagtgaacct
     9541 caactgccaa actccaatta tgaacaaaca aatgaggaat gaactgagat tcataactcc
     9601 cacctgttaa gagttcatag aagttggtca taaagcctaa gacgcccgca atctggccac
     9661 caattccagc aacatagtct tggcgaacca agaaagtaaa aggcatggtc accaagacca
     9721 tcaaaaccac aggtggcaca atccgataaa agcgtcttct aaaaaatcct atcaaatcaa
     9781 tctcattgtt cttagaaaat tcttcaatga gtagagctgt aatcaggaaa cctgaaaatg
     9841 tgaaaaagac atctaccccg aaaaatcctc caggaaagat cgtctgaaag aagtgataca
     9901 agagtaccaa aagtaaacct ataatcctaa tcaaggaaaa ccatttaatg cgcatacgag
     9961 tttattcttc ctttcattgt acactttatt ctatcaaaaa aagaagaaaa atcctaagag
    10021 aaaacttagg atttttagct tatatcaatt ccattttaga aattacgtcc tgacttatta
    10081 tagccatatt tttccacaaa atacttacgg aattccaaga gattgtcatc catgatggct
    10141 tgtcgcactt gcttcatcag gttaagcaag aagtaaagat tgtggtagct agtcaagcgg
    10201 ataccaaagg tttcatcagc cttgagcagg tgacgaaggt aagcgcgtgt atagttatta
    10261 catgtgtagc aatcacactc aggatccagt ggcgtaaagt cctcagcaaa ctgggcattt
    10321 ttcacaacca aacgtccttg actggtcata caagtcccgt tacgagcaat tcgagtcggt
    10381 aagacacagt caaacatatc caccccacga atgaccccat cgatcaagct atctggcgct
    10441 cccacaccca tcagataacg aggtttattt tcaggcagca gttgagttgt aaagtccaag
    10501 accgcattca tctcttcatg ggtttctccc actgccaaac caccgataga gtagcctgag
    10561 aaatccatgc tgacaagatc gtgagctgat tggcggcgaa ggtcttcaaa tcctgcacct
    10621 tgcacaattc caaacaaacc ttggtcatgt ggacgacggt gagccttcaa accacactca
    10681 gcccaacggc tggtacgctc gatcgatttc ttaacgtagt cataaggttg ataaaactga
    10741 ggacattcat caaaggacat catgatgtct gaacccagat tattctgaat agagatggct
    10801 ttttctgggg ataggagcat cttagaacca tttagatgat ttttaaaggt tactccttct
    10861 tctgtgatat tacggctatc tgctaaagaa taaacctgaa aaccaccact atctgtcaag
    10921 ataggctggt cccaattcat gaacttgtgg agaccaccag cgcgtgcaat gagttcatct
    10981 ccagggcgaa gccagagatg ataggtgttt gataggataa ttcccgaacc catctccttc
    11041 aattcttcag gtgactgagt tttgacagtg gcttgtgtcc caactggcat aaacataggt
    11101 gtcggaaagg taccgtgggg agtgatgatt tctcctagac gagctcctgt gtgtttttct
    11161 ttcttaatca aacgatattt gattggtgaa tctgacattt tttacctccg aagctgggaa
    11221 agacagtccc agttcataca gtgtgcccaa ggacacactg tatgatttta tcaaaaaaag
    11281 taggaactgt cacgaactat gtataagaac tatggtataa taagagaatg aactatccaa
    11341 aaattgattt aaaaacaatt cgtcaggagt caaaacattt tcaggctgac accccccgtc
    11401 tctttctcct ctatatcctt cccagtatgc tggtcatctt atctggtttt cttaatccct
    11461 tatctcggat ccacgggact gttttagaac agccattttt cagcatactt ggccaaatac
    11521 ttcaaaccta cctctttcct ctactagtct cctttatcgg gactattctt ttgaccagtt
    11581 ccgtctatgc aacactgaca ctcatgaaag attctaaaac ggagccatct gtaaaaaaca
    11641 gcctagctct ctttgatgag gagcgctttt ctcaaacctt tttgacccta cttctcaaac
    11701 gtttctatct ctttttatgg agtatcccta atttacttgg gatttacctc ctcttttata
    11761 gtagcttttt agccaaaaaa ttcgtcaccc tacatcctga gtttccaaat ctagatctct
    11821 catcagttga aaccgagcgt ttcctcatgg tctttggact ctactttctt gcaagtctca
    11881 tcttgatcat tgtaggaaat atcctctata ttccacagta ttatgcctat tcacaggtgg
    11941 aatttcttct ctgttatagt ctagacctag gacaggtccc accaagacga atcctaaaaa
    12001 ctagccgttc ctttatgaag ggctacaagt tccagcactt tgtcctagat ttacagcttc
    12061 ttccttggta cttcctcaat tggattacct ttggcattgc tagtttttca ctcctacctt
    12121 atatccaatg cactaaaatt atgttttacc gagcagtatt ggctcgaaaa cgtccaaaag
    12181 cttgaaggtt tttcccctca agcttttttc tatcaatgag tttctccgcc taccaacttg
    12241 agttcctgat ctccatgttc tatcatagcg ccgattgctg cttctatccc tcgccgaata
    12301 tccactaaac tcatagttgg agtagtcggt ctgttcacca cctgttccat catataagga
    12361 atatgcataa aacctgcctt aacatatgga aatttctttt ctaccaaata gagagcctga
    12421 tacatcaaat ggctgcagac aaaagtccct gccgtattgg aaacagaggc cggtaagccc
    12481 tcttttttta tagcttgaac catcgcttta atcggcaaac tactaaagta ggccgaagca
    12541 ccatctgggc gaatgggacg gtcaatcggt tgattatctt cgttatcaga aatgcgtgca
    12601 tcgtcttgat taatggccac tcgttcaggt gtcacactag ttcttccacc agcttgccca
    12661 atacaaagga caaagtcagg ttgataacga ttcatctctt cttccaatac ttgagcagat
    12721 ttgtgaaaaa ctgtcggcac ctctagccaa cggacctcag caccatggat ttcagctggt
    12781 aaacctttaa tggcctccaa agttggattg cccttttccc ctccaaaggg ctcaaaacct
    12841 gtcactaata ctttcatttc taactcctca aaaccaattc aatgagactt ttttcttaaa
    12901 aacaagtata acatatttcc cttattctgg attaaaaagg attagcgaga ttaaaatcga
    12961 ccttcaagtg tatttaaaga gtaaaatact aatcaaggcc aaaatagctg atccaccttg
    13021 cttcaaaata atttttttat ccgctgttaa agagccgtaa gtcgcagcac caatcacaaa
    13081 taagacaaaa atagtcacaa tttctaaatt ctgtgagaaa taaatgccat accagagaaa
    13141 gactcctagc agagccttat aaatcccttg atttttgaac aatgaactta ctgacggatg
    13201 agccaattct tccttttcca tattaaatac acgactagtc gcatctgatc gcgtagcaat
    13261 actttccaaa taaaaaatgt aaaaatgctc caaagcaacg atcgttgtta aaataattgt
    13321 aataattgac atctatttct ccttaaattt ctatattttc aatacccaaa accaatttat
    13381 ttaataaacg gctgagttct gttctctcaa actctgttaa gatactttcc atctcttcct
    13441 taaccttgat atgttgcaga gggggattca ccactaactg ctccttggca tacttcgcag
    13501 cctctaccaa cacttcccgc tgattttcag gattacgatg acgctccacc aaaccttccg
    13561 tttccaaaat cttgaaatgc cgtgtcaaag cagcctgatc aattttcaaa cgctcctgaa
    13621 ccgccatttg gttacaagga gaatgctcca gcaaaaacag taaaatctga taccgtgtca
    13681 aactaatccc aagccttttt tcaaacaatt gcgtactcgc ttgctcagac aagcggagtt
    13741 gatacagtaa atcttgaatc tctatcattt cttcctccta tccattgact tatcaatagt
    13801 tgaccaatca attataatat aaagtatagt gaaatgaaat aagagcagga caaatcgatc
    13861 aggacagtca aatcgatttc taacaatgtt ttagaagcag ttgtgtacta ttctagtttc
    13921 aatctactat aaaatagatt gcaagaatgt tgcttagatt attacaagat gataactttc
    13981 cattttccat tcaaattgat actcaatgaa aatcaaaaag caaactagga agctagtcgc
    14041 aggttgctca aagcacagct ttgaggtttc agataaaact gacgtggttt gaagagattt
    14101 tcgaagagta tgacaaagaa aaaacgaacg agaatcgctt cccatcacga aagctagatc
    14161 tcattcgtca aaatgatgtt accaagtcgg gtttatccat tcattgaaac gtgaacgtga
    14221 tcatagtgat tttctgtcac actaccacgg tctggcattg ggttccaagt gttagctggc
    14281 ccatatttgc tatcgaatgg agcatagaaa cgttgtttcc agatgatgta actaatgcca
    14341 cggctggcca tgttttgaat agcatattcc gcaatcttat cccctaattc tgaacgttct
    14401 ggtaccataa agtcgatagc caaacctttt ccgtgatctc cactgtctcc tggacgataa
    14461 ccgctaaagg atgtaatgcc aaacaagtta gcaatttctt ctttaaaggc agctgtttgt
    14521 ggttgaagac ctgcattttc agattttgct actgcaagtc cagcataatc gggcgcagct
    14581 ggagcctcgt aagttgttga aattattttc gtctcttctg gttgataagt agaaactgct
    14641 gctgtagctc catttgatga tgctacttct tttgcttctg aacttgttgt agttgcttcc
    14701 actgctgatg cagcttgagg gcttgcttgt gtttcctgct tctcagctgg agtcgttccc
    14761 tgaggagctt cttctgcaac tgcactgctt gtttcggccg tttgctcctc tgggacagaa
    14821 gtgcccgtag atggtgccac ttcttcagaa gcaatcactg tctttgtaac ttctgaactt
    14881 gatgctactt cttttggagc ttctgcaatt ggttgagaaa ggtctgcaac ctgaacagtt
    14941 tgatcatcaa cggtcacttg attagtggtc aaatctgctg tcgcagttgt cacttcttca
    15001 ctagagtctg cttgaggtgt ttggatttca acttctgtta cttcttctgc ttcattgaca
    15061 gtcgttgtca aaacagtttc tgggaaaatc aagtccatat tagtgatttt gttcagattc
    15121 gcaagcactg tgacatctac acccaaggct tctgcaatgg tgctcaaagt atcaccatac
    15181 tgtacggtat aacttgtttt gttgtccgtt ttagtcaaat cgttttggat ttgctcaaca
    15241 ctacgtgcag tccaaagaac ttcttctgct tgagttgcca atactggggc aaatgacaag
    15301 gctactgttg acgctaataa cattcttttc ttcattcttt caaattcctt tcaaatgagt
    15361 acctgtctat cataacacaa aaaatgtaga aaaaaagccc tctcgggcct atttaacaga
    15421 actgtctatt ccttgtaaca aactagatta cttgaaatag tttgttaggt ctctgtcaca
    15481 aaactgacac aatcttttta tcacttagtc tcaaaaatac gggaaatatc tgctaacgct
    15541 tgaatcctgt gattcccttc ataagtagac tctaaaaagt tgatactttg aatcccacta
    15601 ttctgggcaa attccacatc cagagtccga tcccctatat aataagtatt atcagaattc
    15661 aactgatact tatctagcag ataggtagcc gcttctggac ttggcttccg cacaaagcca
    15721 ctctgactgg tcaaaatctc tgtaaaatag gattccaccc ccaagtcctt gagaatggta
    15781 aaagtgttgt tccccttatg agtatatata aactgctgaa ttcctgattc gtctgcccaa
    15841 gctagcacct cacgcgcacc tggcatcaaa actacctgag cattcttctc agccagactc
    15901 tgggcacgca cctgatttag cacctcaaca tccagatttc tatcttctgc cacccgcaca
    15961 agcaaatttt gcaccgaata cttgaagata aactctctca ccttctcctt atcataagga
    16021 atagaaaact gagcaaaagt ctcctcaatc cctgataaaa tcgcttcgta agagtccaat
    16081 aaagtcccgt ctaaatccca aataaaagct gttttttgca tttcctatcc tttcaagctc
    16141 atatagcgct ggtaacgata gcgtagaaat aaccagcgaa aaccattatc caagagagac
    16201 cctgcccaaa taccaggcaa gccccaacca agcacaatac ccatcagata tcctgtccca
    16261 atgcggatac accacatgcc tatacttgtc gcataaaaag ggaggcgtgc atttcctaat
    16321 ccctgccaga ctgccgtata gatgactgtt cctgtcgtca taggggtacc aagtagtgaa
    16381 aacagtgtca ctagaacact agcctccacc gctagagaat cagtcgtata gagatgagtt
    16441 aatggtacac ccaagacata tatactaaag gacaggggca acatgaggaa cagagaaagc
    16501 caaaaggttt gtttactcaa actagcaact cttttccaat catcctctcc aactgctcgg
    16561 gccaacagca tgaccgttgc cgtagcgaca ccaaaggcag gcatatagtt aaactgggtc
    16621 aagacttctc cgattgcatt cccagcaact gcctccgtcc caaaagaaac gaccaaggca
    16681 atgatcacta catctccagc cctcatcata agtcgctctc cagctgctgg taaagccaag
    16741 gtcaacagtt ccttatctaa accaaaagtt agcttcccat aaggcagttt taattgtgac
    16801 cacaaaatca caagaccaac caaacgagac agaattgtcc cccaagcaac accagctatc
    16861 cccatatcca gaacaaaaat agctagactt gaaaaaagaa tattcaaggc attggataaa
    16921 aaactaacat agagaggcag acgtggatta tgcgttgcac gaatcaaggc tcccaaacta
    16981 gtcattaaac ctaagagaac aatcgatccg cctaccaaag atagatacag tccaccactc
    17041 tcagctacat ccctctccgt ccccaaaagt cctatcatct ctttcccagc gaagatggac
    17101 aaaaatccta aaaggaaact taatagtaag gtaatcttca acgcctcagt cacatgatag
    17161 gccaacttcg actggtcttt ctgccctatg ctttttgaaa taacactgga aatagcagct
    17221 cccagagcga tgaaaatcgc ctgataaatg gtgataatat taccagctac tgaaacccct
    17281 gaaatagcta tcaatcctaa atgagcaacc aaataactgt ccaccattcc cattagcatc
    17341 tgcaaaaagt tttcacccat agctggcaat gcaatattaa gaatgtcttt atttttctta
    17401 aacaatctct cctcctgatg aaaagaaact cagttggttt cccaaccgag tttgctccct
    17461 ctgtcttaaa gtcctaaata agcctcaacc gctgcttgca tgtcagcagc tgccactgtt
    17521 gtcttgtgac gaattggagc tatttcaagc ccatcaactg ctggtggcac tgcaacgcct
    17581 gagatttcat gtaattgagc caaggcttca aagtctgtca aacctgcttt tccagttaca
    17641 gcttctactg caactactgg gaacttgtat ggactagctg ttgaagcaat cactgtctta
    17701 gttacatctc cagtaaccgc ttggtatttt ctataaactg ctgaggcaac cgccgtatgt
    17761 ggatcctcaa tataagaatc tgactcataa acacgcttga tttctgccgc tgtttcttcc
    17821 tcagtcgcat attcagctgc aaagaggtcc aaaatctctg catcaaagtc tgtcaactta
    17881 tattgtcctt gcgtgttcaa ggcattcata agttcagctg tcttttcagc attatttccc
    17941 aaaagatgga aaatcaagcg ctccaagttt gaagatacca agatatccat agatgggctg
    18001 gttgttacct taaactcacg ttttttgtca tagacacgtg ttttaaagaa gtctgtcaag
    18061 acattattgt catttgaagc acagattagc ttgccaactg gtaggccgat ttgtttggca
    18121 taaaaggcag ccaagatatt tccaaagttt cctgttggta ctgtgaagtt aaccttttca
    18181 ccagctacaa tttcaccagt cttaaccaat tgagcgtaag cataaacata ataaacaatt
    18241 tgtggcacca gacgaccaat gttcatagag ttagctgatg aaaattgcaa cttgttggta
    18301 gtcaattttt cacgaagagc cacgtcgtta aacatgtgct tcacatttgt ttgcgcatcg
    18361 tcaaaattac catcaatagc aataacatga gtattgtcac cattctgagt ggtcatttgc
    18421 aactcttgta ccttgctgac accacccttt ggataaaaga cgataatctc agtaccaggc
    18481 acatccgcaa accccgccat agcagctttc cccgtgtcac cagatgtcgc tgtcaagata
    18541 acaatcttgt tctccaaacc atgtttctta gcagcagtcg tcataaagta tggcaaaata
    18601 gacaaggcca tatccttaaa ggcaatcgtt gaaccatgga aaagttccaa attgtattgc
    18661 ccatctaatt tcactaatgg tgcaatagct ggagtatcaa atttgctatc gtaggcattg
    18721 ttgatacagt agtccaactc ctcagctgta aagtcatcta aaaatgctga caaaactagc
    18781 ttagcaactt cctggtaaga agcatctttc aatttgtcaa agtccaaatc tacctttgga
    18841 taagtaaccg gtgtaaacaa accgccgtcc gtcgccaaac cttgcaaaat tgcttggctg
    18901 gcagttactg tattgttggc atcacgcgtt gattgataaa ctaatgtcat tactctctat
    18961 cctttatcta tagtctcgtc cattatatca tgatttttca gaaaattctc cctttataag
    19021 agaaattata ggctcaattc ttctctcaaa ggctgtaaat aggtcatttc ttccttattt
    19081 ctcaccacta gtccctcctc agctagtagg agtaagtctt tggaaaattc aataatcgta
    19141 gtttcttcct catctgtaag atttttctta gaaaattgtc tccttaaaga cttgtaatca
    19201 taaccaaata ctttaaagaa aggtgctgtt tctaagtaag cttctaactt gtctaaatta
    19261 accaataatc ccaagtgaaa agctgcagaa gcaaaagtcc tatcaagtgg ctgtgtacac
    19321 acactacgaa actcaactgt tcctcgagtc gttaaatctt ggtactggta actacgatga
    19381 gtttcaaaat ccttctcttg ggggtaaata ataacctcat ccccattcag agcaaatgct
    19441 tggatttcgg acgtagccaa atagtcccca gcctgaatag gataaaaata ataggtctgc
    19501 ccatcacgtt ccgcagtaaa aatcgcagaa tgatttagat agtcaaaaaa atcagcttca
    19561 tcattaagga gtctagcatt gaccccaaca ttctctggat agataccatg catagattct
    19621 tcccagaaaa tatcccttga aattttcgta tcccaatccg cacccgaaaa ttcagagttt
    19681 gaaaataaat aagccttagc cgcttcaatt tgagtaaaag cattaatcac ccgtaagtag
    19741 ttggtttttg aaatatccag ctgaacctgg ctcccacaga taaaagtacc atattcaggg
    19801 aaatgatgta aatctgattt aataatattt ctactcaaat tcaaataatc catcaacatc
    19861 tgatagcgtg gataagccac tggacaattc tcatttttat cccagttggg atggatacca
    19921 cagccaacaa tagcatgatt tgattcagct aactttctct gaattacatt catataatta
    19981 ttgaaacgat tttcgacctc ttgaatcgtt tcagccttac caaatgcaaa ctcaatcgtt
    20041 gtataggaaa cttcaaataa aatagcatcc tgacttatcg gatctactaa ctggatcaga
    20101 ttgccaaaat catctacctt tgctacggtg agatccaaag tagaaactaa ataatgaaat
    20161 agatccttta taacttcaac atctgtagca tccccttcta aacttgcaac aggatactcc
    20221 aactcaattc cgacaaacaa ttcaggattt tctttaatat ttttcaaata ccgatgtttt
    20281 aataaatcga tagaacaaga catactaccc tacactttct taatctaaat aaaatttgaa
    20341 taactataat tataccaaaa ataatataaa aaaggaacga agaataacaa cgttcctaac
    20401 actatactat accggcggcc ggggtcgaac cggcacgtcc ttgcggacac tggattttga
    20461 gtccagcgcg tctgccaatt ccgccacgcc ggcaaatagt aactggggta gctggattcg
    20521 aaccaacgca tgagggagtc aaagtccctt gccttaccgc ttggctatac cccaataata
    20581 taaaataggc gagtgatggg gatcgaaccc acgcatgcca gagccacaat ctggtgtgtt
    20641 aaccacttca ccacacccgc cataattcta ttaacacggg cagtaggaat tgaacccaca
    20701 ctgaaggttt tggagacctt agttctacct ttaaactatg cccgtaaaat ggaaggggag
    20761 ggattcgaac ccccgaaccc gaaggagcgg atttacagtc cgccgcgttt agcctcttcg
    20821 ctacccttcc aaaatata
//
LOCUS       DAVBEO010000040        20770 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 009
            SAMEA1678075-rid20185393.denovo.040, whole genome shotgun sequence.
ACCESSION   DAVBEO010000040 DAVBEO010000000
VERSION     DAVBEO010000040.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678075
            Sequence Read Archive: ERR226392
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 20770)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20770)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980207.1
            Genome Coverage       :: 150x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:50:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 72 of 147
            Pseudo Genes (incomplete)         :: 72 of 147
            Pseudo Genes (internal stop)      :: 42 of 147
            Pseudo Genes (multiple problems)  :: 32 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20770
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678075-rid20185393.denovo.040"
                     /strain="KS 009"
                     /db_xref="taxon:1313"
     gene            complement(<1..285)
                     /locus_tag="VQ543_001500"
     CDS             complement(<1..285)
                     /locus_tag="VQ543_001500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019770457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET2612204.1"
                     /translation="MLYVGIDIAKNKHDVTALNVPGKTVLKPLTFSNNKAGFELLDLS
                     LRQLNQDCLIALENTGHYAFNLLNFLHEQGYKVYTYTPLLIKEFAKSLSLR"
     gene            540..1385
                     /locus_tag="VQ543_001501"
     CDS             540..1385
                     /locus_tag="VQ543_001501"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000273482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HET2612205.1"
                     /translation="MYLIEILKSIFFGIVEGITEWLPISSTGHLILAEEFIQYQNQNE
                     AFMSMFNVVIQLGAILAVMVIYFNKLNPFKPTKDKQEVRKTWRLWLKVLIATLPLLGV
                     FKFDDWFDTHFHNMVSVALMLIIYGVAFIYLEKRNKARAIEPSVTELDKLPYTTAFYI
                     GLFQVLALLPGTSRSGATIVGGLLNGTSRSVVTEFTFYLGIPVMFGASALKIFKFVKA
                     GELLSFGQLFLLLVAMGVAFAVSMVAIRFLTSYVKKHDFTLFGKYRIVLGSVLLLYSF
                     VRLFV"
     gene            complement(1532..2593)
                     /gene="dinB"
                     /locus_tag="VQ543_001502"
     CDS             complement(1532..2593)
                     /gene="dinB"
                     /locus_tag="VQ543_001502"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000904550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase IV"
                     /protein_id="HET2612206.1"
                     /translation="MLIFPLLNDLSRKIIHIDMDAFFAAVEIRDNPKLRGKPVIIGSD
                     PRQTGGRGVVSTCSYEARAFGVHSAMSSKEAYERCPQAVFISGNYEKYKSVGLQIRAI
                     FKRYTDLIEPMSIDEAYLDVTENKLGIKSAVKIARLIQKDIWQELHLTASAGVSYNKF
                     LAKMASDYQKPHGLTVILPEQAEDFLKQMDISKFHGVGKKTVERLHQMGVFTGADLLE
                     VPEVTLIDRFGRLGYDLYRKARGIHNSPVKSNRIRKSIGKEKTYGKILLAEEDIKKEL
                     TLLSEKVALNLHQQEKAGKIVILKIRYEDFSTLTKRKSLAQKTQDASQISQIALQLYE
                     ELSKKERGVRLLGITMTGF"
     gene            2941..5265
                     /gene="pflB"
                     /locus_tag="VQ543_001503"
     CDS             2941..5265
                     /gene="pflB"
                     /locus_tag="VQ543_001503"
                     /EC_number="2.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase"
                     /protein_id="HET2612207.1"
                     /translation="MVVKTVVEAQDIFDKAWEGFKGVDWKEKASVSRFVQANYTPYDG
                     DESFLAGPTERSLHIKKIVEETKAHYEETRFPMDTRPTSIADIPAGFIDKENEVIFGI
                     QNDELFKLNFMPKGGIRMAETTLKENGYEPDPAVHEIFTKYVTTVNDGIFRAYTSNIR
                     RARHAHTVTGLPDAYSRGRIIGVYARLALYGADYLMQEKVNDWNAIKEIDEETIRLRE
                     EVNLQYQALQQVVRLGDLYGVDVRKPAMNVKEAIQWVNIAFMAVCRVINGAATSLGRV
                     PIVLDIFAERDLARGTFTESEIQEFVDDFVMKLRTVKFARTKAYDQLYSGDPTFITTS
                     MAGMGNDGRHRVTKMDYRFLNTLDNIGNSPEPNLTVLWTDKLPYNFRRYCMHMSHKHS
                     SIQYEGVTTMAKDGYGEMSCISCCVSPLDPENEEQRHNIQYFGARVNVLKALLTGLNG
                     GYDDVHKDYKVFDIEPIRDEVLEFESVKANFEKSLDWLTDTYVDALNIIHYMTDRYNY
                     EAVQMAFLPTKQRANMGFGICGFANTVDTLSAIKYATVKPIRDEDGYIYDYETIGDYP
                     RWGEDDPRSNELAEWLIEAYTTRLRSHKLYKDAEATVSLLTITSNVAYSKQTGNSPVH
                     KGVYLNEDGSVNLSKLEFFSPGANPSNKAKGGWLQNLNSLSSLDFSYAADGISLTTQV
                     SPRALGKTRDEQVDNLVTILDGYFENGGQHVNLNVMDLNDVYEKIMSGEDVIVRISGY
                     CVNTKYLTPEQKTELTQRVFHEVLSMDDALDALS"
     gene            complement(5632..5850)
                     /locus_tag="VQ543_001504"
     CDS             complement(5632..5850)
                     /locus_tag="VQ543_001504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2612208.1"
                     /translation="MMSIREQDLQDIGAIIKYKNFHSPFDTFKYLKDMGFDTIDLSVL
                     LEGFSYAYGMDWLEKFFKENQDKLREFY"
     gene            complement(5946..6184)
                     /locus_tag="VQ543_001505"
                     /pseudo
     CDS             complement(5946..6184)
                     /locus_tag="VQ543_001505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397100.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(6177..6461)
                     /locus_tag="VQ543_001506"
     CDS             complement(6177..6461)
                     /locus_tag="VQ543_001506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002923859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2612209.1"
                     /translation="MDWYDYMIQASKQSQFNASHWFRYLRKVIFEDYSYLTNQDVEKL
                     LDSKELTRFQKISLKYAFQEHTPTHKYVISLNKPAKLTNVQKLMEKYKHG"
     gene            complement(7073..7243)
                     /locus_tag="VQ543_001507"
     CDS             complement(7073..7243)
                     /locus_tag="VQ543_001507"
                     /inference="COORDINATES: protein motif:HMM:NF024172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET2612210.1"
                     /translation="MTKQVPKFTKDTAQLYTCKWLLYNKVTKMYDHTVVNHSVREYIT
                     DSISTNTIEETG"
     gene            complement(7893..9116)
                     /locus_tag="VQ543_001508"
     CDS             complement(7893..9116)
                     /locus_tag="VQ543_001508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000628995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family transcriptional regulator"
                     /protein_id="HET2612211.1"
                     /translation="MITKQSAFLQNRATILEFLYRNPATSRTDIVNETGLTPATTTNI
                     IKELSEQSLIYETGDEFSEFSGSGRRRKTISITDNIPYVVGGIEINVLGIFLSLCDLQ
                     GKTLFETEILNEDYPISEINSTITNMIKTAIEYVPLETKLLGFGLSIPGHYNKDSGSI
                     ITNNPIWESFNLLNVIKRFNFPFIVKNNIDCMAIGQYLFNPHNTPDNFIFLHAGLGIY
                     TSFFTKEKIGASKNPYIGEIGHTIVELNGQYCECGKKGCLQTYISDAWLIKHAQLLFK
                     NSQLTVLKSLVKTEKDIHLDTLLTAYNLGDSALRQQIDKGVNLLATSIANLLLINPAD
                     KIYINSQLLNYQPFTHEVRDKIQDQLHFVPFTRNIEIEILPYNKHRGSIGACALAIVA
                     FFIEHSNVLQDIISP"
     gene            9284..10606
                     /locus_tag="VQ543_001509"
     CDS             9284..10606
                     /locus_tag="VQ543_001509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001059752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HET2612212.1"
                     /translation="MNNILAFLETKVAPFGEKVGNQRHLKAIREGFMMAMPLILVGSL
                     FLILISWPQEDFTNWLNSVGLLSILTTMNQSTVAIISLVACFGIAYRLSEGYGTDGPS
                     AGIIALSSFVLMAPRFSSMVYDKNGEQVKQLFGGAIPFSSLNASSLFMAITIGLVTAE
                     IYRMFIQRGITIKMPSGVPDVVSKSFSALLPGFTTFVLWALVLKGLEAAGVAGGLNGL
                     LGAIVGTPLKLIAGTLPGMILCVIVNSFFWFCGVNGGQVLNAFVDPVWLQFTTENQEA
                     VAAGQTLQHIITLPFKDLFVFIGGGGATIGLAICLFLFSKSRANKTLGKLAIIPSIFN
                     INTAILFTFPTVLNPIMLIPFIATPTINALITYVSMAVGLVPYTTGVILPWTMPPIIG
                     GFLATGASWRGALLQVVLILVSVAIYYPFFKIADKRNLEKEKATVGGK"
     gene            10608..12494
                     /locus_tag="VQ543_001510"
     CDS             10608..12494
                     /locus_tag="VQ543_001510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000236922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4838 domain-containing protein"
                     /protein_id="HET2612213.1"
                     /translation="MVIRVFDQQKNTYSSFALEELSYYINRVFKTDIELVEEKEADIF
                     VGLVNKEDRKDHVLISLDKGKGRIESNTIVGLLIGIYRMFHEFGVVYTRPGRGHDFVP
                     ELRFEDFLDKELSIDETASYYHRGVCIEGADSFENILDFIDWLPKIGMNSFFIQFENP
                     YSFLKRWYEHEFNPYLNKEKFSNELVQELSDRLDKELQKRGLIHHRVGHGWTGEVLGY
                     SSKFGWESGLSISEEKKPYVAEINGKRELFNTAPILTSLDFSNPDVADKMVEIIKDYA
                     KKRPDVNYLHVWLSDARNNICECENCRQELVSDQYIRILNQLDRALTSEGLDTKICFL
                     LYHELLWAPQKEKLDNPERFTMMFAPITRTFEMSYADVDFDNSIPTPKPYLRNKIILP
                     NSLEENLSYLFEWQKTFKGDSFVYDYPLGRAHYGDLGYMKISQTIYRDVSYLSNLHLN
                     GYISCQELRAGFPHNFPNYVMGEMLWKKTRSYEELIEEYFSALYGSNWQSVVEYLEKL
                     SSYSSCDYFNAIGSRQNDVLANHYYIAYNLADNFLPIIEENISKLLNSQKDEWKQLSY
                     HREYVVKMAKALYLQATGKTRQAQDEWRNVLNYIRGHELLFQSNLDVYRVIEVAKNYA
                     GFHL"
     gene            12662..13006
                     /locus_tag="VQ543_001511"
     CDS             12662..13006
                     /locus_tag="VQ543_001511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000836781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HET2612214.1"
                     /translation="MKSKEEINMLGFTIVAYAGDARSDLMDALAFARDGYFEQARELV
                     ESANDSIVSAHREQTNLLAEEASGDNFEVSFIMIHGQDTLMTTMLLYDQVKFFIDEYE
                     RIRKIEEHIGLQ"
     gene            13016..14428
                     /gene="lacG"
                     /locus_tag="VQ543_001512"
     CDS             13016..14428
                     /gene="lacG"
                     /locus_tag="VQ543_001512"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000429433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HET2612215.1"
                     /translation="MENLQVKALPKEFLLGAATAAYQVEGATRVDGKGTNMWDVYLQE
                     NSPFLPDPASDFYYRYEEDITLAAEHGLQALRLSISWVRIFPDIDGEPNILAVRYYHR
                     VFQSCLKHNVIPFVSLHHFDSPQKMLETGDWLNRENIDRFIRYARFCFQEFTEVKHWF
                     TINELMSLAAGQYIGGQFPPNHHFQLSEAIQANHNMLLAHALAVLEFHQLGIEGEIGC
                     IHALKPGYPIDGQKENILAAKRYDVYNNKFLLDGTFLGYYSEDTLFHLNQILEANNSS
                     FIIEDGDLEIMKRAAALNTMFGMNYYRSEFIREYKGENRQEFNSTGIKGQSSFKLNAL
                     GEFVKKPGIPTTDWDWNIYPQGLFDMLLRIKEEYPQHPVIYLTENGTALKEVKPEGEN
                     DIIDDSKRIRYIEQHLHKVLEARDRGVNIQGYFIWSLQDQFSWANGYNKRYGLFFVDY
                     ETQKRYIKKSALWVKGLKRN"
     gene            14498..16177
                     /locus_tag="VQ543_001513"
     CDS             14498..16177
                     /locus_tag="VQ543_001513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HET2612216.1"
                     /translation="MDKLVAAIEKQQGKFEKISTNNYMIAIKDGFIATMPLIMFSSFL
                     MIIIMIPKNFGVELPSPAIAWMRKVYMLTMGVLGIIVSGTVAKSLAGNVNRKMPPGKV
                     INDTSAMLAAICGYLVLTVTLVVDEKTGSTSLSTNYLGSQGLITSFVSAFITVNVYRF
                     CIKRDITIHLPKEVPGAISQAFRDIFPFSFVLLISGLLDIVSRFSLDVPFAQVFQQLL
                     TPIFKGAESYPAMMLIWFMCALLWFVGIHGPSIVLPAVTALQLSNMEENAQLLANGQF
                     PYHSLTPNFGNYIAAIGGTGATFVVPFILIFFMRSKQLKSVGKATITPVLFAVNEPLL
                     FGMPVILNPYLFVPFLMTPPVNVFLGKVFIDFFGMNGFYIQLPWAFPGPLGLLIGTNF
                     QLISFVFLSLMLVVDILIYLPFCRAYDRQLLVKEDIASSNDIILEEDTSEIMPGEIDV
                     IKSKELKVLVLCAGSGTSAQLANAINEGAQLAEVRVIANSGAYGAHYDIMGVYDLIIL
                     APQVRSYYREMKVDAERLDIQIVATRGMEYIHLTKSPSKALQFVLEHYQAV"
     gene            complement(16303..17742)
                     /locus_tag="VQ543_001514"
     CDS             complement(16303..17742)
                     /locus_tag="VQ543_001514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HET2612217.1"
                     /translation="MNKSMIRYLLSKLLLIEAVLLLVPVAIAVYYRESSQVFTALFST
                     IGILVLLGGSGSLQKPKNQRIYAKEGVLIVALCWILWSFFGGLPFVFSGQIPSLIDAF
                     FEISSGFTTTGASILNDVSVLSRSLLFWRSFTHLIGGMGVLVFALAIMDNAKNSHLEV
                     MKAEVPGPVFGKVVSKLKNTAQILYLLYLALFSLFVIIYYLAGMPLYDSFVIAMGTAG
                     TGGFTVYNDGIAHYGSSLITYLVSIGVLVFGVNFNLYYYLMLRRIKAFFGDEELRAYL
                     VIVLVSTGLISLNTLYLYPGFSKSFEMTFFQVSNIITTTGFGYGDITNWPLFSQFILL
                     FLMAIGGSAGSTAGGLKIIRGLILSKIAKNQILSILSPHRVLTLHVNKTVIDKDTQHK
                     ILKYFVIYAMILLALIFIVSLDSNDFLVVTSAVFSCFNNIGPILGTTSSFSIFSPISK
                     ILLSFAMIAGRLEIYPILLLFMKRTWSKR"
     gene            complement(17746..19095)
                     /gene="trkA"
                     /locus_tag="VQ543_001515"
     CDS             complement(17746..19095)
                     /gene="trkA"
                     /locus_tag="VQ543_001515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Trk system potassium transporter TrkA"
                     /protein_id="HET2612218.1"
                     /translation="MKIILVGGGKVGFALCRSLVAEKHDVLLIEQDEAVLNHIVSRFD
                     IIGILGNGADFAILEQASVQDCDIFIALTEHDEVNMIAAVLAKKMGAKETIVRVRNPE
                     YSNSYFKEKNILGFSLIVNPELLAARAIANIIDFPNALSVERFAGGRVSLMEFVVKST
                     SGLCQMPISDFRKKFGNVIVCAIERDHQIIIPSGDMTVQDKDRIFVTGNRVDMILFHN
                     YFKSRAVKSLLIVGAGRIAYYLLGILKDSRIDTKVIEINPEIASFFSEKFPNLYIVQG
                     DGTAKDILLEESAQHYDAVATLTGVDEENLITSMFLDRVGVQKNITKVNRTSLLEIIN
                     APDFSSIITPKSIAVDTIMHFIRGRVNAQYSDLQAMHHLANGQIETLQFHIKEANKMT
                     AKPLSQLKLKKGVLIAAIIRKGKTIFPTGEDMLEVGDKLLVTTLLPNITKIYDLIAR"
     gene            19283..20131
                     /locus_tag="VQ543_001516"
     CDS             19283..20131
                     /locus_tag="VQ543_001516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-adenosyl-l-methionine hydroxide
                     adenosyltransferase family protein"
                     /protein_id="HET2612219.1"
                     /translation="MNNNLLVLQSDFGLVDGAVSAMIGVALEESPTLKIHHLTHDITP
                     YNIFEGSYRLFQTVDYWPEGTTFVSVVDPGVGSKRKSVVAKTAKNQYIVTPDNGTLSF
                     IKKHVGIVAIREISEVANRRQNTEHSYTFHGRDVYAYTGAKLASGHITFEEVGPELSV
                     EQIVELPVVATIIEDHLVKGAIDILDVRFGSLWTSITREEFYKLEPEFGDRFEVTIYH
                     ADMLVYQNQVVYGKSFADVRIGQPILYINSLYRLGLAINQGSFAKAYNVGVGSSWTIE
                     IKKIEG"
     gene            20146..20694
                     /locus_tag="VQ543_001517"
     CDS             20146..20694
                     /locus_tag="VQ543_001517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000403170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF-type riboflavin transporter
                     substrate-binding protein"
                     /protein_id="HET2612220.1"
                     /translation="MEIKFTIKQVVAVGIGAALFVVIGMINIPTPVPNTSIQLQYAVQ
                     ALLSIIFGPIIGLLVGLIGHAIKDSLVGYGLWWTWIIASGLFGLVVGLFRKYVRVING
                     VFDWKDILIFNLIQLLANALVWGVLAPLGDVVIYQEAAEKVFAQGIVAGIANGVSVAI
                     AGTLLLLAYAGTQTRAGSLKKD"
BASE COUNT         6294 a         3524 c         4258 g         6694 t
ORIGIN      
        1 gcgaagtgat aatgatttgg caaattcctt gatgagcaaa ggagtgtagg tgtaaacttt
       61 atatccttgt tcatgcagga agttcagtag attaaaggca taatgtccgg tattttcaag
      121 agcgatgaga cagtcttggt tgagctgtcg aagagacaga tctaagagtt caaaaccagc
      181 tttattattt gaaaaagtga gtggtttaag aacagttttt cctggaacat tcaaggctgt
      241 aacatcgtgt ttatttttag cgatatcaat gcccacataa agcatgggag tacctccaga
      301 tatagtattt caagtctact tggttatcca cgaatttttt gccttgttac cttagacgag
      361 atcaaacgtc tatgcgttat caaactcatt accaattgaa acaaaagctg tggttagagc
      421 ctttcggaaa tcgtcaagcg attggaggaa atgaactaat ccacagtggc ttattccaag
      481 tataccactt gggctttggc agtagctaac tgcgctaatt ataatatagg gagtaatcta
      541 tgtatcttat tgaaatttta aaatctatct tcttcgggat tgttgaagga attacggaat
      601 ggttgccgat ttccagtaca ggtcacttga ttttagcaga ggaattcatc caataccaaa
      661 atcaaaatga agcctttatg tccatgttta atgtcgtgat tcagcttggt gctattttag
      721 cagttatggt gatttatttt aacaagctca atccttttaa accgactaag gacaaacagg
      781 aagttcgtaa gacttggaga ctatggttga aggtcttgat tgctacttta cctttacttg
      841 gtgtctttaa atttgatgat tggtttgata cccacttcca taacatggtt tcagttgctc
      901 tcatgttgat tatctacggg gttgccttca tctatttgga aaagcgcaat aaagcgcgtg
      961 ctatcgagcc aagtgtaaca gagttggaca agcttcctta tacgaccgct ttctatatcg
     1021 gactcttcca agttcttgct cttttaccag ggactagccg ttcaggtgca acgattgtcg
     1081 gtggtttgtt aaatggaacc agtcgttcag ttgtgacaga atttaccttc tatcttggga
     1141 ttcctgttat gtttggagct agtgccttaa agattttcaa atttgtgaaa gccggagaac
     1201 tcttgagctt tgggcaattg tttttgctct tggtcgcgat gggagtagct tttgcggtca
     1261 gcatggtggc tattcgcttc ttgaccagct atgtgaaaaa acacgacttc accctttttg
     1321 gtaaataccg tatcgtgctt ggtagtgttt tgctacttta cagttttgtc cgtttatttg
     1381 tataagaaaa accttgaagg ggcaactctt caaggtttta tactcttcga aaatctcttc
     1441 aaaccgcgtc agctttatct gcaacctcaa aacagtgttt tgagcagcct gcggctagcc
     1501 tcctagtttg ctctttgatt ttcattgagc tttaaaatcc agtcatggta atccccaata
     1561 ggcggacacc tctttctttc ttgcttaatt cttcatagag ttgcagggct atttggctta
     1621 tctgactagc atcttgtgtt ttttgagcaa gactttttcg tttggtaaga gttgaaaagt
     1681 cctcgtagcg gattttcaaa atgacaattt ttccagcttt ttcttgttga tgtagattga
     1741 gagcgacttt ttctgataga agagtcagct cttttttgat atcttcctca gcaaggagaa
     1801 tcttcccgta ggttttctcc ttgccgattg atttacggat gcgattggat ttgactggag
     1861 agttgtgaat gccacgagcc tttcgataca gatcatagcc tagtctacca aaacggtcta
     1921 ttagggttac ctcaggaact tcaagtaaat cagcaccagt aaaaacgccc atttgatgaa
     1981 gacgttctac tgtctttttt cctactccat gaaatttgga aatatccatt tgtttgagaa
     2041 aatcctcagc ctgttcaggt agaatcactg tcaaaccatg tggtttttga taatcactcg
     2101 ccattttagc taagaatttg ttgtaagaaa cgcctgcgga agcagttaga tggagttctt
     2161 gccagatatc tttttgaatg aggcgagcaa ttttgaccgc tgacttgata ccgagtttat
     2221 tttctgtcac atccaaatag gcttcgtcaa tgctcatggg ttcaatcaaa tctgtatagc
     2281 gcttaaaaat agctcgaatc tggagtccca cagacttgta tttctcataa ttccctgaga
     2341 taaagacagc ctggggacaa cgttcataag cttccttgga actcatggca gaatggacac
     2401 caaaagctct tgcctcataa ctacaggtag aaacgactcc ccgtccacct gtttgccgag
     2461 ggtcgcttcc aataatgaca ggttttcctc tgagtttagg attatccctg atttccactg
     2521 cagcaaaaaa ggcatccatg tcaatatgga tgatttttct tgacaaatca tttaacaaag
     2581 gaaaaatcaa catgcctagc acctttttat actcttcgaa aatctcttca aaccacgtca
     2641 gctctatctg caacctcaaa acagtgtttt gagcaatctg cggctagctt cctagtttgc
     2701 ttttcgattt ccattgagtg ttactgctta ttttctttta ttataccctt ttttctgaaa
     2761 aaaagaaaaa aggactttat tttttcaaaa atataataca gtttgaaata aaatatagac
     2821 tgttttagaa aagaaagtgt aaaaataggg aattttcact tgttgaaatc ggttactata
     2881 tggtatactt gtcttatgaa tgtaacagat gactgttact agaaaaaaga ggacattaat
     2941 atggttgtta agacagttgt tgaagcacaa gatatttttg acaaagcttg ggaaggcttc
     3001 aaaggcgtag attggaaaga aaaagcaagt gtatcacgat ttgtacaagc taactacaca
     3061 ccttatgatg gagacgaaag cttccttgca ggaccaacag agcgttcact tcacatcaag
     3121 aaaattgtag aagaaactaa agcacactac gaagaaactc gtttcccaat ggacactcgt
     3181 ccaacatcta tcgctgatat ccctgctgga tttatcgaca aagaaaatga agttatcttc
     3241 ggtatccaaa acgatgaact cttcaaattg aacttcatgc caaaaggtgg tatccgtatg
     3301 gctgaaacta ctttgaaaga aaatggatac gaaccagacc cagctgttca cgaaatcttc
     3361 actaaatatg taacaacagt taacgacggt attttccgtg cctacacttc aaatattcgt
     3421 cgcgctcgtc acgcacacac tgtaactggt cttccagatg catactcacg cggacgtatc
     3481 atcggtgttt acgcacgtct tgctctttac ggtgcagact acttgatgca agaaaaagta
     3541 aatgactgga atgcaatcaa agaaatcgat gaagaaacaa tccgtcttcg tgaagaagta
     3601 aaccttcaat accaagcatt gcaacaagtt gttcgcctgg gtgaccttta cggggttgat
     3661 gttcgcaaac cagcgatgaa cgtgaaagaa gcaatccaat gggttaacat tgctttcatg
     3721 gctgtctgcc gtgtgattaa cggtgctgct acatctctag gtcgtgtacc aatcgtattg
     3781 gacatctttg cagaacgtga ccttgctcgt ggtacattta ctgaatcaga aatccaagaa
     3841 ttcgttgatg atttcgttat gaaacttcgt acagttaaat ttgctcgtac aaaagcttat
     3901 gaccaattgt actcaggtga cccaaccttt atcacaactt ctatggctgg tatgggtaac
     3961 gacggtcgtc accgtgttac taagatggac taccgtttct tgaacactct tgacaacatc
     4021 ggtaactcac cagaaccaaa cttgacagtt ctttggactg acaaattgcc atacaacttc
     4081 cgtcgctact gtatgcacat gagccacaaa cactcttcta tccaatacga aggtgtaaca
     4141 acaatggcta aagacggata tggtgaaatg agctgtatct catgctgtgt gtctccactt
     4201 gatccagaaa atgaagaaca acgccacaac atccagtact tcggtgctcg tgtaaacgtt
     4261 cttaaagccc ttcttactgg tttgaatggt ggttacgacg atgttcacaa agactacaaa
     4321 gtatttgata tcgaaccaat ccgtgacgaa gttcttgaat ttgaatcagt taaagcgaac
     4381 tttgaaaaat ctcttgactg gttgactgac acttacgtag atgccttgaa catcatccac
     4441 tacatgactg ataggtacaa ctacgaagct gttcaaatgg ccttcttgcc aactaaacaa
     4501 cgtgccaaca tgggattcgg tatctgtgga tttgctaaca ctgttgatac attgtcagct
     4561 atcaaatacg ctacagttaa accaatccgt gacgaagatg gctacatcta cgattacgaa
     4621 acaatcggtg actacccacg ctggggtgaa gatgacccac gttcaaacga attggcagaa
     4681 tggttgatcg aagcttacac aactcgtcta cgtagccaca aactatacaa agacgcagaa
     4741 gctacagtat cacttttgac aatcacatct aacgttgctt actctaaaca aactggtaac
     4801 tcaccagttc acaaaggtgt atacctcaac gaagatggtt ctgtgaactt gtctaaactt
     4861 gaattcttct caccaggtgc taacccatct aacaaagcta aaggtggttg gttgcaaaac
     4921 ttgaactcac tttctagcct tgactttagt tatgcagctg acggtatctc attgactaca
     4981 caagtatcac ctcgcgctct tggtaagact cgtgatgaac aagttgataa cttggtaaca
     5041 atccttgatg gttacttcga aaacggtgga caacacgtta acttgaacgt tatggacttg
     5101 aacgatgttt acgaaaaaat catgtcaggc gaagacgtta tcgtacgtat ctctggatac
     5161 tgtgtaaaca ctaaatacct cactccagaa caaaaaactg aattgacaca acgtgtcttc
     5221 cacgaagttc tttcaatgga tgacgccttg gatgcattga gctaatcaag ttcttgaata
     5281 ataaaaagga accctcggtc aaacgactga gggttttgtg cttgggatag tatgagcaat
     5341 tccttcggcg caatatgcaa tgtttttggg aaggaatagt ggaccgaatc tgaaatataa
     5401 tagattgaaa ctagaatagt acacctttac ttctaaaaca ttcttagaaa tcgatttgac
     5461 tgtcctgatc gatttgtcct attcttattt cattttacta tagtccgctg aaacggctca
     5521 aacagtgcta gaaattgact ggaattctct aagtgatttg ttccgatttt atttcatttc
     5581 atcataaaaa taagatgact ggctaattga caatcatctt gtttgatact gttaataaaa
     5641 ttcgcgaagt ttatcttgat tttctttaaa aaatttttct aaccaatcca taccataagc
     5701 ataactaaaa ccttctaata gaacagagag gtcaatagta tcaaatccca tgtcttttaa
     5761 atatttaaag gtatcgaatg gtgaatgaaa gtttttgtat ttaataattg caccaatatc
     5821 ttgcaaatcc tgctctctga tactcatcat cttcattcct aacacatact caatagggac
     5881 tactaaaacg gtcagattct caaatgagta caaggattcg cataaactta agggaggttg
     5941 tttgttcata tttgctttgc aacatgattg ttgagccata actcttcgtg gatgttaaga
     6001 ttaaactgtt ttcctacacg agcaataatt tcattgattt tctgattttg gtcataaaaa
     6061 gcatcaacat cttgtgtggc acgtaaacca tgatattcta agacataacc ataattgtta
     6121 aagtcagatt ttcctgaatt aatttcttat ttagggcttg gaagaccggt ttcattttat
     6181 ccatgtttgt atttctccat caatttttga acattggtta acttagcagg tttatttaat
     6241 gaaatcacat atttatgagt tggagtatgc tcttgaaagg catacttcaa gctaattttt
     6301 tgaaaacggg ttagttcttt ggagtctagc aacttttcta catcttggtt tgttaaataa
     6361 gaatagtctt caaaaataac ttttcgcaaa tagcgaaacc aatggcttgc gttgaattgt
     6421 gattgtttgg atgcctgtat catataatcg taccaatcca ttgtcttcct cctataaaat
     6481 ttagtttata ttattgtagt ttatattcaa aaatgtagtt tttcttaatt agctcgtatc
     6541 tataggatga tactgaaaat cttcttgttg ctttaaatca caatcgaaaa attctgtttt
     6601 tcatcttaga aaagaatgtt tagaaatgta aaatgaacct tttttcttat ccgaaaacct
     6661 tactaaagta tataatttag gcagtcaatt ctgtatgata atgtttgtac tatcgtcgag
     6721 tttttgcttg attgcctaac gagataaatt ttagaagagt tttcggtgtg atttgacaag
     6781 tttctgactg gaaggatagt tacactagta ttgtttatta aaatgagcag atagagaaaa
     6841 tttggaatct atttgcttat tatcaatcgt ttttttagct tatttgtctt agattggtat
     6901 agaactgagc tatggattaa tcttcttcta tcttatcctg ttcctaaata tgttggtaga
     6961 aaaatgaagc agttgttacg agtgtctgta ttgggaaaaa ttttgtctat agaattcttt
     7021 aaatgatatg aaggctagga atgccaaaac actgacatat ttcgtttaaa gtctatccag
     7081 tctcttcaat tgtatttgta gaaatgctat cagtaatata ttcgcgaaca ctatgattta
     7141 caacagtgtg gtcgtacatc tttgtaactt tattatacaa caaccattta caggtgtaaa
     7201 gttgagcagt gtctttagta aatttaggga cttgttttgt catagttttg atacctgtat
     7261 tcgttgtttc atgagcattt gacgtttctt ttcatgtagg catttcaaca attagaatga
     7321 tatttttccg aggatgaact tatatattgt gactttttag agttatgatg cctcttgatt
     7381 tgactaccgc tatcaatttc atccactttt acagtttcat ggttttatga accgaaacat
     7441 ctaggtacag gttttagcat caattgattg tttttgagcc atatgaagtt gaaacgtgga
     7501 gatgcttttc ttgtgataac gccctattca aagaggaata accgtttttg gagagagttc
     7561 agtactatgt ggcgctaaat actatatgta aaacatatat taaacaagat ttaactaagg
     7621 agaattgtaa aaacaaaaat gagaatttca tataaagttt attctaggag tatgtatctt
     7681 gaataaaaat cgttatttaa gttcagggtt atgatgaatg tttttataat aataaaatgc
     7741 agctagaaga aaagttattt taatataaat cactcaacat agagagaagg cggtttccta
     7801 tatggaagtc gtcttgtttt catattgtct aaatacgaga tatctactac aggttatagt
     7861 tgatttaaac aggtctatag atttctaata tattaaggtg aaataatatc ttgtaataca
     7921 ttgctatgtt ctatgaaaaa agcgacgata gctaatgcac aagctcctat acttccacga
     7981 tgtttgttgt aaggtaaaat ttcaatttct atattacgag taaagggaac gaagtggagc
     8041 tggtcttgga ttttatccct gacttcatga gtgaaaggtt gataattaag caattgactg
     8101 ttgatataga ttttatcagc aggattgatg aggaggagat ttgcaataga agtggctaat
     8161 aaattgactc ctttatcaat ttgttgacgt aaagcggagt cgcctaaatt ataagccgtt
     8221 aaaagggtgt ctaaatgaat gtctttttca gtctttacaa ggctttttag tacagttagt
     8281 tgggaatttt taaataataa ttgggcgtgt ttgattaacc aagcatccga aatatatgtt
     8341 tgtaaacaac ctttttttcc gcattcacaa tattgcccat tcaattcgac aatggtgtgt
     8401 ccaatttctc cgatataagg atttttagag gctcctattt tttcttttgt gaaaaaggaa
     8461 gtgtaaatac ctaatccagc gtgtaggaaa ataaagttat cgggggtatt gtgtggatta
     8521 aaaaggtatt gtcctatagc catacaatcg atattatttt ttacaataaa aggaaaattg
     8581 aatcttttaa ttacatttaa taaattaaaa gattcccata tggggttgtt tgtaatgata
     8641 cttccggagt ctttgttata atgtccaggt attgataagc caaatccaag taattttgtt
     8701 tccaaaggga cgtactctat agctgttttt atcatattgg taatggtgga attgatttct
     8761 gaaataggat aatcttcatt caaaatttct gtctcgaaaa gagttttccc ttgtaagtca
     8821 catagactga gaaagatacc taggacgttt atttcaatac ctccaacaac atacggaata
     8881 ttatctgtga tagaaatagt ttttctacgt cttccagatc cggaaaactc gctaaattca
     8941 tcaccagttt cgtatatgag ggactgttcg cttagctctt ttatgatgtt agtcgttgtt
     9001 gctggagtaa gtcctgtttc attaacaata tctgtacggg atgttgctgg atttcgatat
     9061 agaaactcca gtatagtggc tctattttgt aaaaaggctg attgttttgt aatcatttgt
     9121 ttcctccttt ggtttatttt atattaaaca taagaaaaaa tcaattaaaa ttattatttt
     9181 atacaaagaa aaaaatattg taaaaacaac aaaaaatata ttgacaacgc tttctgttag
     9241 tggtatattt aatttataaa aaataaaaaa aggagttccg gtgatgaaca atattttagc
     9301 gtttttagaa acaaaagtcg ctccgtttgg tgaaaaagtt ggcaaccaac ggcatttgaa
     9361 agctattcgt gaaggattta tgatggcaat gcctttgatt ttagtcggat ctttatttct
     9421 tattctaatc agttggcctc aagaggattt tacaaattgg ctgaatagtg ttggattgct
     9481 aagtatcttg acaactatga atcagtcaac agtagcgatt atctccttgg tcgcttgttt
     9541 cggtattgcc tacaggttgt cggaaggata tggtacagat ggtccgtcgg cagggatcat
     9601 agccttatcc agttttgtat tgatggcacc tcgtttttcg agtatggttt atgataaaaa
     9661 tggggagcag gtcaagcagt tatttggcgg cgcaatacca ttttctagcc tgaatgcatc
     9721 ttctttgttt atggcgatta ctattggatt ggttacagca gagatttatc gtatgtttat
     9781 ccagcgcgga attacgataa aaatgccaag tggtgtccca gatgtggtaa gtaaatcatt
     9841 ttcagctctt ttacctggct ttactacttt tgttttgtgg gctctggtct taaaaggtct
     9901 tgaagcggca ggagttgcag gaggtctcaa cggactccta ggtgcaattg ttggaacacc
     9961 gcttaagtta attgcaggaa cgcttccagg tatgattcta tgtgttattg taaactcatt
    10021 cttttggttc tgtggagtta atgggggaca agttttaaat gcttttgtag atccagtttg
    10081 gttacaattt actacagaaa accaagaagc tgtggctgca ggacaaacac tccaacacat
    10141 tattacatta ccgtttaaag atttatttgt atttattggt ggcggtggag cgactattgg
    10201 tcttgcgatt tgtctcttcc tatttagtaa gagtcgtgcg aataaaacat taggtaagct
    10261 agctattata ccgtctattt ttaatatcaa tacagctatt ctatttacgt ttccaacagt
    10321 tttaaatccg attatgctga ttccgtttat tgctactcct acaatcaatg ccttaattac
    10381 ctatgtatca atggctgtag gattagtacc ctacacaaca ggtgtaatcc ttccgtggac
    10441 aatgccaccg atcataggag gcttccttgc gacaggagct agttggcgag gagctctatt
    10501 acaagttgtt ttgattttgg tttctgtagc aatttattat ccattcttca aaattgcaga
    10561 taaacgcaat cttgaaaaag aaaaagctac tgttggaggg aaataagatg gttatcagag
    10621 tatttgatca gcagaaaaat acttattcta gctttgcctt agaggaatta agttactata
    10681 taaatcgggt ctttaagact gacatagaac ttgtcgagga gaaggaagcg gatatttttg
    10741 taggattagt caataaagag gatagaaaag accatgttct tatctcatta gacaagggta
    10801 aggggagaat tgagtctaat acaattgtag gtttgcttat tggaatttac cgaatgtttc
    10861 atgaatttgg ggttgtgtat actagaccag ggcgcggaca tgactttgtt ccagagttac
    10921 gatttgaaga ttttttagat aaagagctat ctatagatga aacagccagt tactatcata
    10981 ggggagtatg tatagaggga gcagattcat ttgaaaatat actagatttc attgattggc
    11041 tacctaagat tgggatgaac agttttttca ttcagtttga aaatccctat tcttttttga
    11101 aacgttggta tgaacatgag tttaatccat acctaaataa agaaaaattc tcaaatgaat
    11161 tagtacaaga attgagtgat aggttggata aagaattgca aaaaagaggt cttattcatc
    11221 atcgtgttgg tcatggatgg acaggtgagg ttttaggtta ctcttcaaaa tttggctggg
    11281 aatcaggtct tagtatttca gaggagaaga aaccctatgt cgctgaaata aacgggaaac
    11341 gagaattatt taatacggct ccgattttaa ccagtctgga tttttcaaat ccagatgtgg
    11401 cggataagat ggtagaaatt atcaaggatt atgccaagaa aagacctgat gttaactact
    11461 tacatgtatg gttgtcggat gctcgtaata atatttgtga atgcgaaaac tgtagacaag
    11521 aattggtttc ggatcagtat attcgtattc tcaatcaatt ggatagggct ttaacgagtg
    11581 agggattaga tacaaagatt tgttttctgc tttaccatga gttgttatgg gcgcctcaga
    11641 aagaaaaatt agataatcct gaacgcttta ccatgatgtt tgcaccgatt acaagaacat
    11701 ttgaaatgag ttatgcagat gtagattttg acaattccat acctacgcct aaaccttatc
    11761 tgcgtaataa aattatactt ccgaattctc ttgaggaaaa tttatcttat ctttttgagt
    11821 ggcaaaaaac atttaaagga gatagtttcg tatatgacta tcctttaggg cgtgctcatt
    11881 atggcgattt aggctatatg aaaattagtc aaaccattta cagagatgta tcttatcttt
    11941 ctaacctaca tttgaacggt tacatttcgt gtcaagaatt acgtgccgga ttccctcata
    12001 attttcctaa ttatgttatg ggggaaatgc tctggaagaa gacaagaagt tatgaagaat
    12061 tgattgaaga atacttttct gctttgtatg ggtcaaattg gcagtctgtt gttgaatatt
    12121 tagaaaaatt atccagttat tcctcatgtg attattttaa tgcaattggc agtcgtcaaa
    12181 atgatgtttt agcgaatcat tattatatag cttacaatct agctgataat tttttgccaa
    12241 ttattgagga aaatatttct aagttattaa atagtcaaaa ggatgaatgg aaacagctca
    12301 gttatcatcg tgaatatgtt gttaagatgg cgaaggcttt atatcttcaa gcaaccggaa
    12361 aaacaaggca agctcaagat gaatggagaa atgtgttgaa ttatatccgt gggcacgaat
    12421 tgctatttca atctaatttg gatgtttatc gtgtaattga agtagcaaaa aattacgctg
    12481 gtttccactt ataaatcata agtatagaaa atgaaccaag gtattcagag aagattgatc
    12541 ctaaatatta tgaaatttaa ggatttttaa gatatttagg gtcgactttc tatttatatc
    12601 gtagcgaagt cattttaata atgatgtgta aaagatggat caagattgag gaggaagaaa
    12661 gatgaaatca aaagaagaaa taaatatgct tggttttaca attgtcgctt acgcaggaga
    12721 tgcaaggtca gatttgatgg atgctttggc gtttgcgaga gatggatatt ttgaacaggc
    12781 aagagaattg gttgagtctg caaacgactc aatagtgtct gcccatcgag aacagactaa
    12841 tttattagcg gaggaggcat ctggagataa ttttgaagtg agttttatca tgattcatgg
    12901 tcaagatacc ttgatgacaa cgatgctatt gtatgatcag gtcaagtttt ttattgatga
    12961 atatgaacga attcgaaaga ttgaagaaca tattggtttg caatgaggat tagtcatgga
    13021 aaatttacag gttaaagcct taccgaagga gtttttatta ggagctgcta ccgctgctta
    13081 tcaagtagag ggtgcaacta gggtagatgg caaaggaaca aatatgtggg atgtttattt
    13141 gcaagaaaac agtccgttct taccagatcc agctagtgat ttttattatc gttacgaaga
    13201 ggatataact ttggcggcag aacatggttt gcaggctttg cgtttatcta tttcttgggt
    13261 tcgtatattt cctgatatag atggggagcc taatatatta gctgttcgtt attaccatag
    13321 agtctttcag tcttgcttaa aacataatgt gattccgttt gtttctttac atcattttga
    13381 ttcgcctcag aaaatgttag aaacagggga ttggttgaat agagagaata ttgatcgttt
    13441 catacgatat gctcgctttt gtttccaaga atttacagaa gtcaagcatt ggtttacaat
    13501 caatgaactg atgtctcttg ctgcaggtca atatatagga ggtcagtttc ctccaaatca
    13561 tcattttcaa ttatctgaag caattcaagc gaatcataat atgttgttgg cgcatgctct
    13621 tgcagtcctc gaatttcatc aattaggaat tgagggagag ataggttgta ttcatgcttt
    13681 aaagccaggc tatcctattg atgggcaaaa agaaaatatt ttggcagcta aacggtatga
    13741 tgtttataat aataaatttc tattagatgg aacttttttg ggctactaca gtgaggacac
    13801 gctttttcac ttgaatcaaa tattggaagc taataattct agctttatta ttgaagatgg
    13861 tgatttagaa attatgaaga gagctgcagc tcttaatacg atgtttggga tgaattatta
    13921 tcgttcagaa tttattcgtg aatacaaagg tgaaaataga caagaattta attcaacagg
    13981 aataaaagga cagtcttctt ttaaattaaa tgctctaggt gaatttgtaa aaaaacctgg
    14041 tattccgaca acagattggg attggaatat ttatcctcaa gggttatttg atatgttgct
    14101 tcgtatcaaa gaagaatatc ctcaacatcc ggtcatttat ttaactgaaa atggtacagc
    14161 ccttaaagaa gttaagccag agggcgagaa tgatattatt gatgacagta agagaatccg
    14221 ttatattgag caacatttac acaaagtttt agaggctcga gatagaggag tcaatattca
    14281 aggctatttt atatggtctt tgcaagatca attttcttgg gcgaatggct acaataagcg
    14341 atatggtctt ttctttgttg attatgaaac acagaagaga tatattaaga aaagtgctct
    14401 ttgggtaaaa gggctaaaac ggaattaagg ttagcgattt gactgatgtt taatatattt
    14461 taactatgag cttaaatttt ttacaggagg agtttttatg gataagttag tcgctgccat
    14521 tgaaaagcaa caagggaaat ttgaaaaaat ttctactaat aattatatga tagctattaa
    14581 agatggattt attgctacta tgcctttaat tatgttttca agctttttga tgattattat
    14641 tatgattcct aaaaatttcg gagtagagtt accgagtcca gctattgcct ggatgaggaa
    14701 agtgtatatg ctaaccatgg gagttttggg tattattgtt tcagggacag ttgcaaagtc
    14761 attggctgga aatgttaata gaaaaatgcc tcctggaaag gtaataaatg atacttctgc
    14821 aatgttggcg gccatatgtg gctatcttgt attaactgta acgcttgtag ttgatgagaa
    14881 aacgggatct acaagtttgt cgacaaacta tttaggatct caaggattga taacttcgtt
    14941 tgtcagtgcc tttattactg taaatgttta ccgattctgt attaagcgag acattactat
    15001 tcatttacct aaggaagttc ctggggctat atcacaagct tttagagata tttttccttt
    15061 ttcttttgtt ttacttatta gtggtttgtt agatattgta tctcggttta gtttagatgt
    15121 tccttttgcc caagtatttc aacaactatt gactcctatt tttaaggggg cagaatcata
    15181 tcctgctatg atgttgattt ggtttatgtg tgctttgctt tggtttgttg gaattcatgg
    15241 accatctatt gtcttacctg ctgttacagc tttacaactg agcaatatgg aagagaatgc
    15301 tcaacttctt gcaaatgggc agttccctta tcattcttta acacctaatt tcgggaatta
    15361 tatcgctgct attggaggaa cgggggctac ctttgttgta ccatttattt tgattttctt
    15421 tatgcggtct aaacaattaa aatcggtagg taaagctaca attactcctg ttttatttgc
    15481 ggtaaatgaa cctcttctat ttggtatgcc tgttattttg aatccctatc tttttgtccc
    15541 ttttttgatg actccaccag tgaatgtatt tctaggaaag gtatttattg atttctttgg
    15601 aatgaatgga ttttatatcc agttaccttg ggcctttcct ggtcccttgg gattgttaat
    15661 tggaacgaat tttcaactta tctcctttgt atttttatct ttgatgttag ttgtcgacat
    15721 attgatttat ttgccattct gtagagcgta tgatagacag ttactggtga aagaagatat
    15781 tgcaagctca aatgatatta ttttagagga ggatacaagt gaaataatgc ctggtgagat
    15841 agatgtaata aaaagtaagg agttgaaagt actggttctt tgtgcagggt ctggaacaag
    15901 tgcgcaatta gccaatgcaa ttaacgaggg cgctcaatta gcagaagtta gagtgattgc
    15961 gaattcagga gcgtacggag ctcattatga tattatgggt gtttatgatt taattattct
    16021 ggccccacaa gttcggagtt attatagaga gatgaaggtg gatgcagaaa gattagatat
    16081 tcagatagtt gctaccagag gaatggaata tattcattta acaaagagtc caagtaaagc
    16141 cttacaattt gtattggagc attaccaagc tgtgtagtaa gtttttccat cttttatttg
    16201 agtaaagatt ttgcttacag ataggcttgg atttaaaaac gttccccctt ttttaatata
    16261 agaatccctc tttcacaatt gtaaaaagag ggattttgta ttttatctct tagaccaagt
    16321 tctcttcata aagagaagga ggattgggta aatctccaag cgccctgcaa tcattgcaaa
    16381 ggataggaga atttttgaga tgggactaaa gattgagaaa ctagaagtgg ttcctagaat
    16441 aggcccgata ttattgaaac agctaaagac agcgctggtc acgaccagaa aatcattgct
    16501 atctaggctg acaataaaga taagcgctag caaaatcata gcatagatga caaagtactt
    16561 gagaatctta tgctgggtat ctttgtcaat caccgtttta ttaacatgga gggtcaaaac
    16621 acggtggggc gataggattg acaaaatttg gtttttggca atttttgaaa ggatgaggcc
    16681 tcgaataatc ttgagtccac ctgcagttga tccagcagag ccaccgattg ccatgaggaa
    16741 aaggaggata aactgggaga agaggggcca gttggtaata tctccatatc caaaaccagt
    16801 tgttgtaatg atgttggaaa cctggaagaa ggtcatttca aagctctttg aaaaccctgg
    16861 gtagaggtag agggtgttga ggctaatcaa gcctgtagaa accagtacaa tgaccaagta
    16921 agccctaagc tcttcatctc caaagaaggc cttgatgcga cggagcatga ggtagtagta
    16981 gaggttgaaa tttactccaa aaaccagaac tccgatactg accagatagg taatcagtga
    17041 gctgccatag tgggcaattc cgtcgttata gacggtaaag cctccagttc ccgctgtccc
    17101 catagcaatg acaaaactat cgtagagagg cataccagct agataataga tgatgacaaa
    17161 gagggagaag agagctagat aaaggagata gagaatctgg gcagtgtttt ttagtttgga
    17221 tacaaccttg ccaaaaacag gacctggaac ctcagccttc atcacctcta ggtggctatt
    17281 tttggcattg tccataatag caagtgcaaa aacaagcact cccatccctc caatcaagtg
    17341 ggtaaaactt cgccagaaga ggagggaacg actgagaact gaaacgtcgt tcaaaatact
    17401 tgctccagta gtcgtaaagc cggaactaat ctcaaaaaag gcatcaataa ggctggggat
    17461 ttgcccagaa aagacaaagg ggagaccacc aaagaaagac caaaggatcc aacagagggc
    17521 aacgatcaag actccctcct tggcataaat ccgttgattt tttggcttct gtaaactccc
    17581 tgaaccgcct aacaatacga gaatccctat ggtcgaaaag agggctgtaa agacttggct
    17641 cgattcacgg taatagacag cgatagccac aggaaccaag aggagaacag cttcaatcaa
    17701 aagtaacttt gaaaggaggt aacgaatcat acttttattc atttcttacc tcgcaatcaa
    17761 gtcataaatc ttggtgatgt ttggcaacaa ggttgttact aggagcttgt ctccaacttc
    17821 caacatatcc tccccagttg ggaaaatagt cttgcccttt cgaataatgg ctgcaataag
    17881 aacccctttt ttcaatttca gttgagaaag aggtttggca gtcattttat tggcttcctt
    17941 gatatggaat tgcagggttt cgatttggcc attggctaga tggtgcatgg cttgaaggtc
    18001 tgaatactgg gcattaactc gaccacgaat aaagtgcata atcgtatcta cagcgatgct
    18061 tttaggtgtg atgatacttg aaaaatcagg cgcattgata atctcgagga gactggtacg
    18121 attgacctta gtaatatttt tctgtacacc taccctgtca aggaacatag atgtaatcag
    18181 attttcctca tcgactcctg ttagagtcgc aacggcatca tagtgttgag cactttcttc
    18241 cagcaggata tcttttgcgg ttccatctcc ttgaacgatg tagagatttg ggaatttctc
    18301 gctaaagaag ctggcgattt caggattgat ttcaatgact tttgtatcga tacgactatc
    18361 tttgagaata ccaagtagat aataggcaat tctacctgcc ccaacgatga gaaggctctt
    18421 cacggcgcgt gatttaaaat aattatggaa gagtatcata tcgacacggt taccagtgac
    18481 aaagattcta tctttatcct gtacagtcat gtcaccgctt ggaatgataa tttgatgatc
    18541 cctctctatc gcacagacaa tgacattacc aaatttttta cgaaaatcag aaatgggcat
    18601 ttggcaaaga ccgctggtgg acttgacgac aaattccatg aggctaacgc gtccaccagc
    18661 aaagcgttcg acagacaggg cgttggggaa gtcaatgata ttcgcgatag cacgggcagc
    18721 caagagctca ggattaacga taagagaaaa accgagaata ttcttttcct tgaaataaga
    18781 gttagaatat tcagggttcc gcacccgaac gatagtttct ttagctccca ttttcttggc
    18841 tagaactgct gcaatcatgt tgacttcatc gtgctcagtc agggcgataa agatatcaca
    18901 atcttggacg ctggcttgct caagaatggc aaaatcggcc ccgttaccaa ggataccaat
    18961 gatatcaaag cgactgacaa tatgattgag aacagcttcg tcttgctcaa tcagcaaaac
    19021 atcatgcttt tctgcaacca aggagcgaca gagggcaaaa ccaacttttc cccctccgac
    19081 aaggataatt ttcataataa aacctacttt ttcatgatgt aactatcata ccctttttca
    19141 agaaaaaatg cacctactag ctaataacaa gagcttttag tgaaaattcg ctataagata
    19201 aaactatacc ctaaccaatt gaaatagcta ttagcgactt tctctgaaat atggtatgat
    19261 aaaggatata caaggagata aaatgaataa taatttactg gtattacaat cagactttgg
    19321 tctggttgat ggtgcggtat cggctatgat tggagtggct ttagaagagt ctccaacctt
    19381 aaaaatccat cacttgacgc acgatatcac gccttataat atttttgagg ggagctatcg
    19441 tctctttcag acggtggatt actggcctga gggaacgacg tttgtatcgg ttgtcgatcc
    19501 aggtgtcggt tcgaaacgta agagtgtagt tgccaagact gcaaaaaatc aatacattgt
    19561 cacgccagat aatgggacgc tttcctttat caagaaacac gttggcattg tagccattcg
    19621 tgagatttct gaggtggcca ataggcgtca aaacacagag cattcttata ccttccacgg
    19681 tcgtgatgtc tatgcctata ctggtgctaa actggccagt ggtcacatta cttttgagga
    19741 agtagggcca gagctcagtg tggaacagat tgtagagctt ccagtcgtag cgaccatcat
    19801 agaagatcat ctggtgaagg gagccattga tattctggat gtgcgtttcg gttcgctttg
    19861 gacctctatc acacgggaag aattttacaa gttggaacca gaatttggtg atcgttttga
    19921 agtgaccatc tatcatgctg atatgctggt ctatcaaaat caggttgtct atggcaaatc
    19981 atttgcagat gtgagaattg ggcaacccat cctttacatc aactctctct atcgtttagg
    20041 tttggctatc aaccaaggtt cctttgccaa ggcctataat gtaggtgtcg gttcatcttg
    20101 gaccattgaa ataaagaaaa tagaaggata aaataggaga atagtatgga aatcaaattt
    20161 acaattaaac aagttgttgc tgtcggaatt ggcgctgccc tctttgtcgt catcgggatg
    20221 atcaacattc caacccctgt tccaaataca agcatccagc ttcagtatgc ggtacaagcg
    20281 ctactttcta ttatttttgg accgattatc ggtttgcttg ttgggttgat tggtcatgca
    20341 atcaaggact ctcttgttgg ttatggtcta tggtggactt ggattatcgc tagcggactc
    20401 tttggtttag ttgtgggact ttttagaaag tacgttcgcg tgatcaatgg tgtttttgac
    20461 tggaaagata ttcttatttt taacctcatt caactacttg caaatgccct tgtttggggt
    20521 gtcttggcac cacttggaga tgttgtgatt tatcaagaag cggcagaaaa agtatttgca
    20581 caaggaattg ttgcgggaat tgccaatggt gtatctgtag ctattgcagg aactcttctc
    20641 ttacttgcct atgcaggaac ccaaactcgt gcaggaagtt tgaaaaagga ctaatactca
    20701 atgaaaatca aagagcaaac taggaagtta gccgcaggtt gctcaaaaca gtgttttgaa
    20761 attgtggata
//
LOCUS       DAVBEO010000041        20158 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 009
            SAMEA1678075-rid20185393.denovo.041, whole genome shotgun sequence.
ACCESSION   DAVBEO010000041 DAVBEO010000000
VERSION     DAVBEO010000041.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678075
            Sequence Read Archive: ERR226392
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 20158)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20158)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980207.1
            Genome Coverage       :: 150x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:50:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 72 of 147
            Pseudo Genes (incomplete)         :: 72 of 147
            Pseudo Genes (internal stop)      :: 42 of 147
            Pseudo Genes (multiple problems)  :: 32 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20158
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678075-rid20185393.denovo.041"
                     /strain="KS 009"
                     /db_xref="taxon:1313"
     gene            63..527
                     /locus_tag="VQ543_001518"
     CDS             63..527
                     /locus_tag="VQ543_001518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001146193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldose epimerase"
                     /protein_id="HET2612221.1"
                     /translation="MGGHPGFNCLLLDDEVYEDYYLEFEKEEICSVPRPFPETGMLDF
                     QDRSPWLEGQKEIDLSYDLFSTDAVTLDELQSRTIALRSLKHDKGLKVHFAEFPNLII
                     WSTLNKGPFITFEPWSGLSTFLEEGDHLEDKKNVCLLEANQVEELGFEIEVL"
     gene            685..1110
                     /gene="lacA"
                     /locus_tag="VQ543_001519"
     CDS             685..1110
                     /gene="lacA"
                     /locus_tag="VQ543_001519"
                     /EC_number="5.3.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacA"
                     /protein_id="HET2612222.1"
                     /translation="MSIVIGADAAGLRLKEVVKDFLEKENFHLVDVTAEGQDFVDVTL
                     AVAAEVNKEEQNLGIVIDAYGAGPFMVATKIKGMVAAEVSDERSAYMTRGHNNSRMIT
                     MGAQLVGDELAKNIAKGFVNGKYDGGRHQIRVDMLNKMG"
     gene            1141..1656
                     /gene="lacB"
                     /locus_tag="VQ543_001520"
     CDS             1141..1656
                     /gene="lacB"
                     /locus_tag="VQ543_001520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacB"
                     /protein_id="HET2612223.1"
                     /translation="MRIAIGCDHIVTDEKMAVSEFLKSKGYEVIDFGTYDHTRTHYPI
                     FGKKVGEAVTSGQADLGVCICGTGVGINNAVNKVPGVRSALVRDMTTALYAKEQLNAN
                     VIGFGGKITGELLMCDIIEAFIHAEYKPSEENKKLIAKIEHLESHNAQQTDANFFTEF
                     LEKWDRGEYHD"
     gene            1667..2596
                     /locus_tag="VQ543_001521"
     CDS             1667..2596
                     /locus_tag="VQ543_001521"
                     /EC_number="2.7.1.144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000604270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-6-phosphate kinase"
                     /protein_id="HET2612224.1"
                     /translation="MILTVTMNPSIDISYPLDELKIDTVNRVVDVTKTAGGKGLNVTR
                     VLSEFGDSVLATGLVGGKLGEFLVEHIDDQVKKDFFSIQGETRNCIAILHGDNQTEVL
                     EKGPEVLEQEGQDFLEHFKKLLESVEVVAISGSLPAGLPVDYYASLVELANQAGKLVV
                     LDCSGAALQAVLESPHKPTVIKPNNEELSQLLGREVSEDLEELKEVLQESLFTGIEWI
                     IVSLGANGTFAKHGDTFYKVDIPRIQVVNPVGSGDSTVAGISSGLLHKESDAGLLIKA
                     NVLGMLNAQEKMTGHVNMANYQALYDQLIVKEV"
     gene            2598..3578
                     /gene="lacD"
                     /locus_tag="VQ543_001522"
     CDS             2598..3578
                     /gene="lacD"
                     /locus_tag="VQ543_001522"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001229146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HET2612225.1"
                     /translation="MALTEQKRVRLEKLSDENGIISALAFDQRGALKRLMAQHQTEEP
                     TVAQMEELKILVADELTKYASSMLLDPEYGLPATKALDEKAGLLLAYEKTGYDTTSTK
                     RLPDCLDVWSAKRIKEEGADAVKFLLYYDVDSSDELNQEKQAYIERIGSECVAEDIPF
                     FLEILAYDEKIADAGSVEYAKVKPHKVIGAMKVFSDPRFNIDVLKVEVPVNIKYVEGF
                     AEGEVVYTREEAAAFFKAQDEATNLPYIYLSAGVSAKLFQDTLVFAHESGANFNGVLC
                     GRATWAGSVEAYIKDGEAAAREWLRTTGFENIDELNKVLQTTATSWKERV"
     gene            3812..4648
                     /locus_tag="VQ543_001523"
     CDS             3812..4648
                     /locus_tag="VQ543_001523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000285719.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HET2612226.1"
                     /translation="MYRILNPMNHNVSLVRNDKGEEVIVIGKGIAFGKKKGDLIAENH
                     VEKIFRMKTEESRENFMALLKDVPLDFITVTYEIIDKLSKKYHYPIQEYLYVTLTDHI
                     YCSYQALIQGRYKDSNLPDISAKYPVAFQIANEAFEIYRQKLADHFPEDEIIRIAYHF
                     INAEGENEVELVESIDKRKEILRNVEEVLTDYAIQRTKKNNHFYDRFMIHLNYFLDYL
                     DRSRDDNQSLLDMEDHIKQSYPKAFEIGSKIYDVITQHTGLDLYKSERVYLVLHIQRL
                     LS"
     gene            4684..5001
                     /locus_tag="VQ543_001524"
     CDS             4684..5001
                     /locus_tag="VQ543_001524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HET2612227.1"
                     /translation="MNREEVTLLGFEIVAYAGDARSKLLEALKAAEAGDFEKADALVE
                     EAGSCIAEAHHAQTSLLTKEASGEDLAYSVTMMHGQDHLMTTILLKDLMHHLIELYKR
                     GVK"
     gene            5003..6697
                     /locus_tag="VQ543_001525"
     CDS             5003..6697
                     /locus_tag="VQ543_001525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001037357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HET2612228.1"
                     /translation="MDKLIIFIEKGKPFFEKLSRNIYLRAIKDGFISSMPAVLFSSIF
                     ILIAAVPNIFGFKWSDEQLAFILKPYNYSMGILALLVAGTTAKSLTDSVNTRSMEKTN
                     QINYMSTFLAAVVGLLILAADPIEGGFANGLLGTRGLLTAFLAAFITVNIYKVCIKNN
                     VTIRLPEEVPPNIAQVFKDVIPFALSVLSIYGLDLIVRNIFGTNVAESVGKILAPLFS
                     ATDGYIGLAIVFGAYAFFWFVGIHGPSVVEPLIVAISYANIEANVQLVQAGMHADKIL
                     NPVTQTFVVTMGGTGATLVVPFMFMWLCKSKRNRIVGRASVVPTFFGVNEPILFGAPI
                     VLNPIFFIPFVTAPIINVWIMKFFVDVLQMNSFSIILPWTTPAPIGIVMGTALAPLSF
                     VLAITLIIIDTLIYYPFVKVYDHQILEEERSGKSNDELKEKVAANFNTAKADAILEKA
                     GVDAAQNTITEETNVLVLCAGGGTSGLLANALNKAAAEYNVPVKAAAGGYGAHREMLP
                     EFDLVILAPQVASNFEDMKAETDKLGIKLAKTEGAQYIKLTRDGKGALAFVQAQFD"
     gene            6906..8312
                     /gene="lacG"
                     /locus_tag="VQ543_001526"
     CDS             6906..8312
                     /gene="lacG"
                     /locus_tag="VQ543_001526"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HET2612229.1"
                     /translation="MTKTLPKDFIFGGATAAYQAEGATHTDGKGPVAWDKYLEDNYWY
                     TAEPASDFYNRYPVDLKLAEEYGVNGIRISIAWSRIFPTGYGQVNAKGVEFYHNLFAE
                     CHKRHVEPFVTLHHFDTPEALHSNGDFLNRENIEHFVDYAAFCFEEFPEVNYWTTFNE
                     IGPIGDGQYLVGKFPPGIQYDLAKVFQSHHNMMVSHARAVKLYKDKGYKGEIGVVHAL
                     PTKYPLDPKNPSDVRAAELEDIIHNKFILDATYLGRYSAETMEGVNHILSVNGGSLDL
                     REEDFTALEAAKDLNDFLGINYYMSDWMEAFDGETEIIHNGKGEKGSSKYQIKGVGRR
                     VAPDYVPRTDWDWIIYPQGLYDQIMRVKKDYPNYKKIYITENGLGYKDEFVDNTVYDD
                     GRIDYVKQHLEVLSDAIADGANVKGYFIWSLMDVFSWSNGYEKRYGLFYVDFETQERY
                     PKKSAHWYKKVAETQIID"
     gene            8355..8537
                     /locus_tag="VQ543_001527"
     CDS             8355..8537
                     /locus_tag="VQ543_001527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000471575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3884 family protein"
                     /protein_id="HET2612230.1"
                     /translation="MFKDFIQSIYEKVYIINFEKCSQIPCLTSEELKSLFLNFINPEE
                     WDTISFDSDFMPFQQS"
     gene            complement(8815..9576)
                     /locus_tag="VQ543_001528"
     CDS             complement(8815..9576)
                     /locus_tag="VQ543_001528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000917571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HET2612231.1"
                     /translation="MLKQEKLAKILEIVNSKGTITVKQIMDEIAVSDMTARRYLQELA
                     DKDLLIRVHGGAEKLRTNSLLTNERSNIEKQALQTAEKQEIAHFAGSLVEERETIFIG
                     PGTTLEFFARELPIDNIRVVTNSLPVFLILSERKLTDLILIGGNYRDITGAFVGTLTL
                     QNLSNLQFSKAFVSCNGIQNGALATFSEEEGEAQRIALNNSNKKYLLADHSKFNKFDF
                     YTFYNVSNLDTIVSDSKLSDSILFKLSKHIKVIKP"
     gene            complement(9758..10720)
                     /gene="nrdF"
                     /locus_tag="VQ543_001529"
     CDS             complement(9758..10720)
                     /gene="nrdF"
                     /locus_tag="VQ543_001529"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004253599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HET2612232.1"
                     /translation="METYYKAINWNAIEDVIDKSTWEKLTEQFWLDTRIPLSNDLDDW
                     RKLSNKEKDLVGKVFGGLTLLDTMQSETGVQALRADIRTPHEEAVFNNIQFMESVHAK
                     SYSSIFSTLNTKAEIEEIFEWTNTNPYLQKKAEIVNEIYLNGSPLEKKVASVFLETFL
                     FYSGFFTPLYYLGNNKLANVAEIIKLIIRDESVHGTYIGYKFQLGFNELPEEEQEKLK
                     EWMYDLLYTLYENEEGYTESLYDGVGWTEEVKTFLRYNANKALMNMGQDPLFPDSAED
                     VNPIVMNGISTGTSNHDFFSQVGNGYLLGEVEAMQDDDYNYGLD"
     gene            complement(10908..13067)
                     /gene="nrdE"
                     /locus_tag="VQ543_001530"
     CDS             complement(10908..13067)
                     /gene="nrdE"
                     /locus_tag="VQ543_001530"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000523276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HET2612233.1"
                     /translation="MGLKHLEDVTYFRLNNEINRPVNGQIMLHKDKEALDAFFKENVV
                     PNTMVFDSIKDKINYLIEHNYIETAFIKKYRPEFLEELAQFIKDQNFQFKSFMAAYKF
                     YNQYALKTNDGEYYLENMEDRVFFNALYFADGNEAVAIDIANEIIHQRYQPATPSFLN
                     AGRARRGELVSCFLIQVTDDMNSIGRSINSALQLSRIGGGVGITLSNLREAGAPIKGY
                     EGAASGVVPVMKLFEDSFSYSNQLGQRQGAGVVYLNVFHPDIIAFLSTKKENADEKVR
                     VKTLSLGVVVPDKFYELARKNEEMYLFSPYSVEKEYGVPFNYIDITEKYDELVANPNI
                     RKTKIKARDLETEISKLQQESGYPYVVNIDTANRANPVDGKIIMSNLCSEILQVQEPS
                     LINDAQEFLQMGTDVSCNLGSTNVVNMMTSPDFGRSIRAMVRALTFVTDSSHIVAVPT
                     IDHGNSQAHTFGLGAMGLHSYLAQQLIEYGSPESVEFTSIYFMLMNYWTLVESNNIAR
                     ERGITFHNFEKSDYANGSYFDKYVTGEFVPTSDRVKELFKNVFIPGVADWAELRDKVQ
                     EDGLYHQNRLAVAPNGSISYINDVSASIHPITQRIEERQEKKIGKIYYPAAGLSTETI
                     PYYTSAYDMDMRKVIDVYAAATEHVDQGLSLTLFMRSDIPKGLYEWKRENKQTTRDLS
                     ILRNYAFNKGIKSIYYVRTFTDDGGEVGANQCESCVI"
     gene            complement(13148..13366)
                     /gene="nrdH"
                     /locus_tag="VQ543_001531"
     CDS             complement(13148..13366)
                     /gene="nrdH"
                     /locus_tag="VQ543_001531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000259243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaredoxin-like protein NrdH"
                     /protein_id="HET2612234.1"
                     /translation="MVTVYSKNNCVQCKMTKRFLDSNNVSYREINLDEQPEYVDQVKE
                     LGFSAAPVIQTPTEVFSGFQPGKLKQLA"
     gene            13717..13980
                     /locus_tag="VQ543_001532"
     CDS             13717..13980
                     /locus_tag="VQ543_001532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019775469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphocarrier protein HPr"
                     /protein_id="HET2612235.1"
                     /translation="MASKDFHVVAETGIHARPATLLVQTASKFASDITLEYKGKSVNL
                     KSIMGVMSLGVGQGADVTISAEGADADDAIAAISETMEKEGLA"
     gene            13986..15719
                     /gene="ptsP"
                     /locus_tag="VQ543_001533"
     CDS             13986..15719
                     /gene="ptsP"
                     /locus_tag="VQ543_001533"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate--protein phosphotransferase"
                     /protein_id="HET2612236.1"
                     /translation="MTEMLKGIAASDGVAVAKAYLLVQPDLSFETITVEDTNAEEARL
                     DAALQASQDELSVIREKAVGTLGEEAAQVFDAHLMVLADPEMISQIKETIRAKKVNAE
                     AGLKEVTDMFITIFEGMEDNPYMQERAADIRDVTKRVLANLLGKKLPNPASINEEVIV
                     IAHDLTPSDTAQLDKNFVKAFVTNIGGRTSHSAIMARTLEIAAVLGTNNITEIVKDGD
                     ILAVNGITGEVIINPTDEQAAEFKAAGEAYAKQKAEWALLKDAQTVTADGKHFELAAN
                     IGTPKDVEGVNNNGAEAVGLYRTEFLYMDSQDFPTEDEQYEAYKAVLEGMNGKPVVVR
                     TMDIGGDKELPYFDMPHEMNPFLGFRALRISISETGDAMFRTQIRALLRASVHGQLRI
                     MFPMVALLKEFRAAKAVFDEEKANLLAEGVAVADNIQVGIMIEIPAAAMLADQFAKEV
                     DFFSIGTNDLIQYTMAADRMNEQVSYLYQPYNPSILRLINNVIKAAHAEGKWAGMCGE
                     MAGDQQAVPLLVGMGLDEFSMSATSVLRTRSLMKKLDTAKMEEYANRALTECSTMEEV
                     LELQKEYVNFD"
     gene            15974..18424
                     /gene="phtA"
                     /locus_tag="VQ543_001534"
     CDS             15974..18424
                     /gene="phtA"
                     /locus_tag="VQ543_001534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtA"
                     /protein_id="HET2612237.1"
                     /translation="MKINKKYLVGSAAALILSVCSYELGLYQARTVKENNRVSYIDGK
                     QATQKTENLTPDEVSKREGINAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDAIFSEE
                     LLMKDPNYKLKDEDIVNEVKGGYVIKVDGKYYVYLKDAAHADNVRTKEEINRQKQEHS
                     QHREGGTPRNDGAVALARSQGRYTTDDGYIFNASDIIEDTGDAYIVPHGDHYHYIPKN
                     ELSASELAAAEAFLSGRGNLSNSRTYRRQNSDNTSRTNWVPSVSNPGTTNTNTSNNSN
                     TNSQASQSNDIDSLLKQLYKLPLSQRHVESDGLVFDPAQITSRTARGVAVPHGDHYHF
                     IPYSQMSELEERIARIIPLRYRSNHWVPDSRPEQPSPQPTPEPSPGPQPAPNLKIDSN
                     SSLVSQLVRKVGEGYVFEEKGISRYVFAKDLPSETVKNLESKLSKQESVSHTLTAKKE
                     NVAPRDQEFYDKAYNLLTEAHKALFENKGRNSDFQALDKLLERLNDESTNKEKLVDDL
                     LAFLAPITHPERLGKPNSQIEYTEDEVRIAQLADKYTTSDGYIFDEHDIISDEGDAYV
                     TPHMGHSHWIGKDSLSDKEKVAAQAYTKEKGILPPSPDADVKANPTGDSAAAIYNRVK
                     GEKRIPLVRLPYMVEHTVEVKNGNLIIPHKDHYHNIKFAWFDDHTYKAPNGYTLEDLF
                     ATIKYYVEHPDERPHSNDGWGNASEHVLGKKDHSEDPNKNFKADEEPVEETPAEPEVP
                     QVETEKVEAQLKEAEVLLAKVTDSSLKANATETLAGLRNNLTLQIMDNNSIMAEAEKL
                     LALLKGSNPSSVSKEKIN"
     gene            18582..>20158
                     /locus_tag="VQ543_001535"
     CDS             18582..>20158
                     /locus_tag="VQ543_001535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HET2612238.1"
                     /translation="MKINKKYLAGSVATLVLSVCAYELGLHQAQTVKENNRVSYIDGK
                     QATQKTENLTPDEVSKREGINAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDAIISEE
                     LLMKDPNYQLKDEDIISEIKGGYVIKVDGKYYVYLKDAAHADNVRTKEEINRQKQEHS
                     QHREGGTSTNDGAVAFARSQGRYTTDDGYIFNASDIIEDTGDAYIVPHGDHYHYIPKN
                     ELSASELAAAEAFLSGRGNLSNSRTYRRQNSDNTSRTNWLPSVSNPGTTNTNTSNNSN
                     TNSQASQSNDIDSLLKQLYKLPLSQRHVESDGLVFDPAQITSRTARGVAVPHGNHYHF
                     IPYEQMSELEKRIARIIPLRYRSNHWVPDSRPEQPSPQSTPEPSPSLQPAPNPQPAPS
                     NPIDEKLVKEAVRKVGDGYVFEENGVSRYIPAKDLSAETAAGIDSKLAKQESLSHKLG
                     AKKTDLPSSDREFYNKTYDLLARIHQDLLDNKGRQVDFEALDNLLERLKDVSSDKVKL
                     VDDILAFLAPIRHPERLG"
BASE COUNT         6438 a         3612 c         4158 g         5950 t
ORIGIN      
        1 aactagaatt ctagttttgc aggaagtcta ataaagaaac tagcaaggtc aggccttact
       61 ttattggtgg acatccagga tttaattgtc ttctacttga tgatgaagtc tatgaagatt
      121 attatctaga gtttgagaaa gaagagattt gctctgttcc acgtcctttc ccagaaacag
      181 gtatgttgga tttccaagat agaagtccat ggctagaggg acaaaaagaa atagatctta
      241 gttatgatct tttcagcaca gatgcagtga ctttggatga attgcaatct cgaacaattg
      301 cccttcgttc tcttaaacat gataagggat tgaaagtgca ttttgcagaa tttccaaacc
      361 tcatcatctg gtcaactttg aacaagggac ctttcattac ctttgaacca tggtctggct
      421 tgtcaacatt ccttgaagaa ggagatcatt tagaagataa gaagaatgtt tgtctcttag
      481 aagccaatca ggttgaagaa ttagggtttg agatagaagt tttataaaaa aagtaaaaaa
      541 taaataacaa aaacaaacac aaactgttga cttcttcaaa caatagtagt atattatgtt
      601 tgtgaggact aattgactgt tttttaaaga cagccaatac actgctggaa tccagcatag
      661 aaaaaataaa aaggagtata caatatgtct attgttatcg gtgcagatgc tgcaggtttg
      721 agattgaaag aagttgtgaa agacttctta gaaaaagaaa acttccacct tgtggatgtt
      781 acagctgaag gtcaagactt tgttgatgtg actctcgctg ttgctgcaga agtaaacaaa
      841 gaagaacaaa accttggtat cgtgattgat gcttatggag ctggtccatt tatggttgca
      901 actaagatca aaggaatggt tgctgcagaa gtatctgacg aacgttcagc ttatatgact
      961 cgtggccaca acaactcacg tatgatcact atgggggcac aacttgttgg tgatgaattg
     1021 gctaaaaaca tcgctaaagg atttgttaat ggtaaatacg acggtggacg tcatcaaatc
     1081 cgggttgaca tgttgaacaa aatgggctaa ttagattaca gtaagaaagg taagttaaaa
     1141 atgagaattg caattggatg cgaccacatc gtaacagatg aaaaaatggc ggtttcagaa
     1201 tttttgaaat caaaaggata tgaagtcatt gactttggta catatgacca tacacggact
     1261 cactacccaa tctttggtaa aaaagtaggg gaagctgtaa ctagcggcca agctgatctt
     1321 ggggtatgta tctgtggtac tggtgttggt atcaacaacg ctgtaaataa agttccaggt
     1381 gttcgttctg ccttggttcg tgatatgaca acagcccttt atgctaaaga acaattgaac
     1441 gctaacgtta tcggctttgg tggtaagatt actggtgaat tgcttatgtg tgatatcatc
     1501 gaagctttca ttcatgctga atacaaacca tctgaagaaa acaagaaatt gattgcgaaa
     1561 attgaacacc ttgaaagtca caatgctcaa caaacagacg caaacttctt tacagaattc
     1621 cttgaaaaat gggatcgcgg agaataccac gactaagagg tgacctatga ttttaacagt
     1681 cacaatgaac ccatccattg atatttccta tcccttggat gagttgaaga ttgatactgt
     1741 caatcgtgtg gtggatgtaa ccaaaacggc tggtggtaag ggacttaatg ttacccgagt
     1801 actttcagaa tttggtgatt ctgttcttgc tactggttta gtgggtggca aacttggtga
     1861 gtttttggtt gaacatatcg atgatcaagt aaagaaagat ttcttttcta ttcagggaga
     1921 aactcgtaac tgtatcgcta ttctccacgg tgacaaccaa acagaagttc ttgaaaaagg
     1981 tcctgaagta ttggaacagg aaggtcaaga ctttttggaa catttcaaaa aactcttgga
     2041 gtcagttgaa gtagtagcca tctcaggtag tctgccagct ggccttccag ttgattacta
     2101 tgcgagcttg gtagagcttg ctaatcaagc tggcaagcta gtagtcttgg actgctctgg
     2161 tgcagcactt caggcggttc ttgaatcacc ccataaaccg acagtaatca aacccaataa
     2221 tgaggaattg tctcagcttc taggaagaga agtttctgag gatttggagg aattaaaaga
     2281 agtccttcaa gaatctttgt ttacagggat tgaatggatt atcgtttcac ttggtgccaa
     2341 cggtactttt gccaaacatg gtgacacttt ctacaaggta gatattccta gaattcaggt
     2401 ggtaaatcct gttggatctg gagactctac tgtggcagga atttcttcag gacttcttca
     2461 caaagaatcg gatgcaggat tactcatcaa ggcaaatgtc cttggtatgc tcaatgctca
     2521 agaaaaaatg actggtcatg tcaacatggc caactatcaa gctctatatg atcaattaat
     2581 agtaaaagag gtataaaatg gctttaacag aacaaaaacg tgtacgctta gaaaaacttt
     2641 ctgatgaaaa tggtatcatc tcagctcttg catttgacca acgtggtgct ttgaaacgcc
     2701 tcatggctca acaccaaaca gaagaaccaa ctgtggccca aatggaagaa cttaaaatct
     2761 tggtagcaga tgaattgact aaatacgctt catctatgct tcttgaccct gagtatggac
     2821 ttccagcaac taaggctctt gatgaaaaag ctggtcttct ccttgcttat gaaaaaacag
     2881 gttatgacac aacaagcaca aaacgcttgc cagactgctt ggatgtttgg tctgcaaaac
     2941 gtattaaaga agaaggtgca gatgcagtta aattcttgct ttactatgat gtagatagct
     3001 cagacgaact caatcaagaa aaacaagcct acatcgaacg catcggttct gagtgtgtgg
     3061 ctgaagatat cccattcttc cttgaaatcc ttgcttacga tgaaaaaatt gcggacgcag
     3121 gttctgtaga atacgctaaa gtaaaaccac acaaagttat cggtgctatg aaagtctttt
     3181 cagacccacg ttttaacatt gatgtcttga aagttgaagt tcctgttaac attaaatatg
     3241 ttgaaggctt cgctgagggt gaagtggttt acacacgtga agaagcagca gccttcttca
     3301 aagcgcaaga tgaagcaacg aacttgccat acatctactt gagtgctggt gtatcagcta
     3361 aactcttcca agatactctt gtatttgctc atgaatcagg tgcaaacttt aacggagttc
     3421 tttgtggtcg tgctacatgg gcagggtcag ttgaagctta catcaaagat ggtgaagcag
     3481 cagctcgcga atggcttcgc acaactggat ttgaaaacat tgatgagctc aataaagttc
     3541 ttcaaacaac agcgacttca tggaaagaac gtgtgtaaga aagtcctcct agtttaggaa
     3601 catgaatcta aaaaaattta aaaaaagttg tatgtaaagg tttacaaaat aacttacttg
     3661 tgctatactt aaatcacaag ttaatacaag gtgagtgtta ctaagtaata ttaggcatga
     3721 tcacaggtga attagaaatc agctgatttt ctagttcatt tgtggtcatt ttttgtactc
     3781 atataccttt aagatataaa aggaggttga catgtatcga attctaaatc caatgaatca
     3841 caatgtctcg cttgtcagaa atgataaggg agaagaggtg attgtaattg gtaaggggat
     3901 tgcattcgga aagaagaagg gggatttgat tgctgaaaat catgttgaga aaatctttcg
     3961 gatgaagacc gaagagtcca gagaaaactt tatggctctt ctcaaagatg ttccgcttga
     4021 ttttatcaca gtgacctatg aaatcattga taagctatca aagaaatatc attatccgat
     4081 tcaagagtat ctctatgtaa ccttgacaga tcatatttac tgttcttatc aagctctaat
     4141 tcaaggaagg tacaaggata gtaatctgcc agatatttct gctaagtatc ctgtcgcttt
     4201 tcaaatcgca aatgaagctt ttgaaattta ccgtcagaag ctagcagatc attttcctga
     4261 ggacgaaatt attcggattg cttatcattt cattaatgct gaaggtgaaa atgaagtgga
     4321 acttgtggag tcgattgata agaggaaaga aattctcagg aatgttgaag aagttttaac
     4381 ggactatgca attcaacgaa ctaaaaagaa taaccatttc tatgatcgct ttatgatcca
     4441 tttgaattat ttcttggatt atttagacag atctagagat gataaccaat cacttctgga
     4501 tatggaagat catattaaac aatcctatcc aaaagccttc gagattggtt ccaagatcta
     4561 tgatgtgatt acgcaacata cgggtcttga tttgtataaa agtgaacgag tttatctagt
     4621 tctacatatc caacgtttat tgtcataaaa atttatttaa aactatataa ggagaattct
     4681 atcatgaata gagaagaagt aacattgtta ggttttgaaa tcgtagccta tgctggcgat
     4741 gctcgttcaa aactattgga agccttgaag gctgctgaag ctggtgattt tgaaaaagcg
     4801 gacgctctgg tagaggaagc tggtagctgt attgcagagg ctcaccacgc gcaaacaagt
     4861 ctattgacta aggaagcttc tggtgaggac ttagcgtata gtgtgaccat gatgcatggt
     4921 caagatcact tgatgacaac tatcttgtta aaagacctaa tgcaccattt aattgaactt
     4981 tacaagagag gagttaaata aaatggataa gttaataatt tttattgaga aaggaaagcc
     5041 tttctttgag aaattatcga gaaatatata cttaagagcg ataaaagatg gttttatttc
     5101 cagtatgcca gcagtattat tctcaagtat ttttatacta atagctgctg tgcccaatat
     5161 ttttgggttt aaatggtctg atgaacagtt agcttttatt ttgaaacctt acaactactc
     5221 aatggggatt ttagctctct tagtagctgg gacaactgca aaatcgttaa cagattcagt
     5281 taatacacgt agtatggaga aaaccaacca aatcaactac atgtcaactt ttttagcagc
     5341 tgttgttgga ttgttaatac tggcagctga tccaattgaa ggtggatttg ctaatggtct
     5401 tttaggtact agaggattac ttactgcatt tttggcagct tttattacag taaatatcta
     5461 taaagtatgt attaaaaata atgtaaccat tagacttcct gaagaggttc caccaaatat
     5521 tgcacaagtt tttaaagatg ttattccgtt tgccttatct gttctttcaa tatatggatt
     5581 ggatttaatt gttagaaata tttttggtac aaatgtagca gaatctgttg gtaaaatatt
     5641 agcccctcta ttttcagcta ctgatggtta tatcggttta gctattgtat ttggtgctta
     5701 tgctttcttt tggtttgttg gaattcatgg gccatctgtt gtagaacctt taattgtagc
     5761 tatcagttat gcaaatatag aagctaatgt tcagcttgtg caagctggta tgcacgcaga
     5821 taaaatttta aatccagtta ctcaaacttt tgttgtaaca atgggtggta ctggtgcaac
     5881 actagtagtt ccatttatgt ttatgtggtt atgtaaatca aaaagaaata gaattgtcgg
     5941 acgtgcgtct gtagttccta ctttctttgg cgtaaatgaa ccaatcctat ttggtgctcc
     6001 aattgtttta aatcctatct tctttattcc gtttgttact gctcctatta tcaatgtttg
     6061 gattatgaaa ttttttgtag atgttctaca aatgaatagt ttcagtatta ttttaccttg
     6121 gacaacacct gctccaattg gtattgttat gggaacggcg ctggctccat tgtcattcgt
     6181 cttggctata actttaatca ttatcgacac tttaatctat tatccatttg ttaaagttta
     6241 tgaccatcaa attttagaag aagaacgttc aggtaagtct aatgatgaat tgaaagaaaa
     6301 agttgctgca aacttcaaca ctgcaaaagc ggatgctatt cttgaaaaag cgggtgtcga
     6361 tgcagcacaa aataccatca ctgaagaaac aaatgtcctc gttctctgtg caggtggagg
     6421 aacaagtggt ctccttgcaa atgctttgaa taaggcagca gcagaataca atgtccctgt
     6481 gaaagcagca gcaggcggct atggtgctca ccgtgaaatg ttaccagagt ttgatcttgt
     6541 tatccttgcc cctcaagttg cttcaaactt tgaagatatg aaagcagaaa cagataagct
     6601 cggtattaaa ctagcgaaaa cagaaggcgc tcaatacatc aaattaactc gtgatggaaa
     6661 aggtgctctt gcattcgtac aagcgcaatt cgattaaggc tagagactct gaaatagtct
     6721 cctatcgtta cggaaatcgc tatggcgaat ttcctattat taattcgtcg gtaaaaagat
     6781 atcgttttta cctcctcatg tcacaattcg gtgacttggt acaagaagtg agatggagaa
     6841 ggatggctca ctgactcctc tcctctcact tttactttat ttaaatcaag aaataggtga
     6901 aaaaaatgac aaaaacactt ccaaaagact ttatttttgg tggcgcaaca gctgcctatc
     6961 aagcagaagg tgctacacat actgatggta aaggaccagt agcgtgggat aaatatcttg
     7021 aagataacta ctggtacact gcagaaccag ccagtgattt ttacaatcga tatccagttg
     7081 acctcaagct agcagaagag tatggtgtca atggtattcg aatttctatt gcttggtcac
     7141 gtattttccc gactggttac ggccaagtaa atgctaaagg tgttgagttt tatcataatt
     7201 tatttgcaga gtgtcacaaa cgtcatgttg agccctttgt aactcttcat cactttgaca
     7261 cgccagaagc tctccactca aatggagact tcttaaaccg tgaaaatatc gaacattttg
     7321 tagactacgc tgccttctgt tttgaagaat ttccagaagt aaactattgg acaaccttta
     7381 atgaaattgg gccaattggt gatggtcaat acttggttgg gaaattccct ccaggtattc
     7441 agtacgacct tgccaaagtc ttccaatcgc accacaatat gatggtgtct catgcgcgtg
     7501 cagttaagct atataaagat aaaggctata aaggcgaaat tggtgttgtt cacgctctgc
     7561 caactaagta tcctttagat cctaaaaatc cgtcagatgt tcgtgcagct gagttggaag
     7621 atattattca caataaattt atcttggatg caacttatct aggtcgctat tcagctgaaa
     7681 cgatggaagg tgtcaaccat atcttatcag tcaatggtgg tagcttggat cttcgtgaag
     7741 aagattttac agcattagaa gcagcaaaag acttgaatga tttccttgga atcaactact
     7801 atatgagtga ctggatggaa gcctttgatg gagaaactga aattatccat aatggtaagg
     7861 gtgagaaagg aagttctaaa taccaaatca aaggtgttgg tcgtcgtgta gctcctgatt
     7921 atgtaccacg tacggattgg gattggatta tctaccctca aggtttatat gaccaaatta
     7981 tgcgtgtgaa gaaagattat cctaactaca agaagattta catcactgaa aatggtctcg
     8041 gctataaaga tgagttcgtc gataacactg tttatgatga tggacgtatt gattatgtga
     8101 aacaacactt ggaggtcttg tctgatgcga ttgcagatgg agcgaatgta aaaggttact
     8161 tcatttggtc attgatggac gtcttttcat ggtcaaatgg ttatgaaaaa cgttacggtc
     8221 tcttctatgt agactttgaa actcaagaac gttatccgaa gaaatcagct cactggtaca
     8281 agaaagtagc ggaaactcag attatagact agtagaatta gtcattagat atagaatttt
     8341 agtgagtcaa aaagatgttc aaagatttta tccaatctat ttatgaaaaa gtttatatta
     8401 taaatttcga aaaatgctct caaataccgt gtttgacgag tgaagaattg aaaagtctat
     8461 ttttaaattt tatcaatcct gaagaatggg atactatctc ctttgattca gattttatgc
     8521 catttcaaca atcgtaacca atttctcaaa aaagttaaat cttatattta gtactctgca
     8581 aaactcttat ctaatcacgt tgcttatact caatgaaaat caaagagcaa ctttaaacta
     8641 ggaagcgagt cgcagatttc tcaatgcata gctttgagga attgggcaaa aagtctttga
     8701 tatagaaaaa gcatagtatc aggtgtttca acacctgata ctatgctttt tattgtggga
     8761 agatttactt tttttcttct gaaattgagt tgttacccag gctctttcag tttattaagg
     8821 cttgatgact ttaatgtgtt tagatagctt aaaaaggatt gaatcactta gtttagaatc
     8881 tgaaacaata gtatcaagat ttgatacatt ataaaaagta taaaaatcaa acttattgaa
     8941 cttactatga tctgcgagta aatatttttt attagaatta tttaaagcga tgcgttgagc
     9001 ctctccctct tcctcgctaa aagtagctag agctccgttt tgaataccat tacagctaac
     9061 gaaagcttta gaaaattgga gattagagag attttgtagg gtcaatgtgc caacaaaagc
     9121 acctgtaata tcgcgataat ttccacctat caaaatcaaa tctgttaatt ttcgttcgct
     9181 taaaatcaga aaaacaggta gactgttggt tacgacgcgg atattgtcaa taggcaactc
     9241 acgcgcaaaa aactctaatg ttgttcctgg tccaatgaaa atagtttctc tttcttctac
     9301 tagactgcct gcaaaatggg ctatttcttg tttttctgcc gtttggaggg cttgtttttc
     9361 aatatttgat cgctcattag tcaaaaggga gttggttcga agtttttcag ctccaccatg
     9421 cacacgaatc agcaaatctt tatcagctaa ttcctgtaaa tagcgccttg cagtcatatc
     9481 tgaaacggct atttcgtcca taatctgttt aactgttatg gttcctttac tatttactat
     9541 ctctaaaatt ttggctaatt tttcttgttt gagcatatta tcacctcgtt tcctactact
     9601 atcttaccat aaacaaactc atcattcaaa tacaaaaaca acaaaatgaa acaaaaacaa
     9661 aaatatcgaa gtttgttttc aaaactttcg atatttttgt tgggttataa ctttgatgtt
     9721 tctagtttac tttttgatga ttgagagtga tggagaatta gtctaaaccg tagttatagt
     9781 catcgtcttg catggcttca acttcgccaa gaaggtaacc atttccgact tgagagaaga
     9841 agtcatggtt ggaagttcct gttgaaatac cgttcataac gattgggttg acatcttcag
     9901 ctgaatctgg gaaaagtgga tcttgtccca tgttcatgag agctttattg gcattgtagc
     9961 gaaggaaggt tttaacctct tcagtccaac caacaccgtc ataaagactc tctgtgtagc
    10021 cttcttcatt ttcataaaga gtatagagta ggtcgtacat ccattctttg agtttttctt
    10081 gctcttcttc aggcaattca ttgaaaccaa gttggaattt gtaaccaatg taggttccgt
    10141 gaacagactc gtcacgaata atcaatttaa tgatttctgc aacgttggct agtttgttgt
    10201 taccgagata gtagagggga gtgaagaaac cagagtagaa gaggaaggtt tcgaggaaga
    10261 cgctggcaac tttcttttca agtgggctgc cgtttaggta gatttcgttg acaatctcag
    10321 ccttcttttg taggtaagga ttggtattgg tccattcgaa aatttcttca atctcagcct
    10381 tagtattcaa ggtagaaaag attgatgagt aagatttagc gtggacagat tccataaatt
    10441 ggatgttatt gaaaacagct tcctcatgtg gtgtacggat gtctgcgcga agggcttgaa
    10501 ccccagtttc agattgcata gtgtcaagaa gggttaaacc accaaaaact tttccgacca
    10561 agtctttctc tttgttagat agctttctcc agtcatccaa gtcgtttgat aagggaatac
    10621 gtgtatcgag ccaaaattgc tccgtcagtt tttcccaagt tgatttgtcg atgacatctt
    10681 cgatggcatt ccagttaatg gctttgtagt aagtttccat ttaaaatctc tttctgtgtt
    10741 tagtattgcg aactcacaat tatttctact ttaccataat tctataggag tatcgcacaa
    10801 aaagtcggaa gcccgacttt taaaatgtta cataaattat gttatgacat agtagatttg
    10861 attttatcag tgctgcttag ggaaaaataa tgtttctatg ctagaaacta aatcacacag
    10921 ctttcacatt ggttggcgcc gacttctcca ccgtcatctg taaaggtacg gacgtagtag
    10981 atagacttga ttcccttgtt aaaggcatag ttacgaagga tggacaagtc acgtgtcgtt
    11041 tgtttatttt ccctcttcca ttcgtaaagg ccttttggaa tgtcactacg catgaagagg
    11101 gtgagtgaaa gtccttgatc cacgtgttca gtcgcagcag cgtaaacatc gatgacttta
    11161 cgcatatcca tatcgtaggc agaagtgtag taaggaatgg tttctgtaga caagccagca
    11221 gcagggtagt agattttacc aattttcttc tcttggcgtt cttcgatacg ttgcgtaatc
    11281 gggtggatag aagcagaaac gtcgttgata tagctgatag aaccatttgg cgctacagca
    11341 aggcgatttt ggtggtaaag accatcttct tgaaccttgt cgcgaagttc agcccaatca
    11401 gcaacaccag ggataaagac atttttgaag agttctttaa cacggtctga tgttggaaca
    11461 aattcaccag ttacatactt gtcaaagtaa cttccgttag catagtctga tttttcaaag
    11521 ttgtggaagg taataccacg ttcacgcgca atattgtttg actctaccaa ggtccagtag
    11581 ttcataagca taaagtagat gcttgtaaat tcaacagact caggtgaacc atattcaatg
    11641 agttgttggg caaggtagct gtgcagtccc atggcaccga gaccaaaggt gtgggcttgg
    11701 ctatttccat ggtcaatcgt tggtacagct acgatatgtg aactatctgt aacgaaagta
    11761 agggcacgaa ccatagcacg gatagaacga ccaaaatcag gtgaagtcat catgttaacc
    11821 acgttggttg aacccaggtt acatgaaaca tctgttccca tttgaaggaa ttcttgagca
    11881 tcgttgatca agcttggttc ttgaacttga agaatctcag aacacaagtt actcatgata
    11941 atctttccat caacaggatt tgcacggtta gccgtatcga tgttgactac ataaggatag
    12001 ccagactctt gttgcaattt agagatttca gtttccaaat cccgcgcctt gatttttgtc
    12061 ttgcgaatat ttggatttgc gaccaattca tcgtattttt cagtaatgtc gatgtaattg
    12121 aatggcacac cgtattcttt ttctacagag taagggctga agaggtacat ttcttcattt
    12181 ttacgagcca attcgtagaa tttatcaggt actacaacac caagtgatag agtcttgaca
    12241 cgtacttttt catcagcgtt ttctttctta gttgaaagga aagcgatgat atctgggtga
    12301 aagacgttga ggtagacaac accggcacct tgacgttgcc ccaattggtt ggagtaagag
    12361 aagctgtctt caaaaagctt cataacagga acgacacctg aagcagctcc ttcatagcct
    12421 ttgataggtg caccagcttc acgaaggttg ctgagggtaa ttcccacacc accaccaata
    12481 cgtgaaagtt gaagagctga gttgatagaa cgtccgatag agttcatatc atccgtcact
    12541 tggattagga aacaagatac caactctcca cggcgagcac gtccagcatt caagaaggaa
    12601 ggagtagcag gttggtagcg ttggtggatg atttcattgg caatatcgat tgcaacagct
    12661 tcattcccat cagcgaaata aagggcgttg aagaagacac ggtcttccat attttcaaga
    12721 tagtattcac cgtcattagt ctttaaggca tattgattgt aaaatttata agctgccatg
    12781 aatgacttga attggaagtt ttggtctttg ataaattgag ctaattcttc caagaactct
    12841 ggacggtatt tcttgataaa ggctgtttcg atgtagttgt gttcaatgag gtaattgatt
    12901 ttgtctttga ttgaatcaaa aaccatagtg tttggaacta cattttcttt aaagaaagca
    12961 tccaaggctt ccttgtcttt atgaagcatg atttgtccat taacaggacg gttaatttcg
    13021 ttattaagac ggaagtaagt cacgtcttca agatgtttta atcccataaa atttccctta
    13081 tctaattaca aaagaaaggc ttctaagtta gccctaaaag cagtttcttc tggatgatgt
    13141 actaagatta tgctaattgt ttcagttttc ctggttggaa acctgaaaag acttcagttg
    13201 gtgtttggat aacaggagct gcgctaaaac cgagctcttt aacttgatcg acgtactcag
    13261 gttgctcatc aagattgatt tcacgataag agacattatt actgtccaag aaacgcttgg
    13321 tcattttaca ttggacacaa ttgtttttag aataaacggt taccattgtg taactcctct
    13381 tcaaaattta atactatctt agtatatcag aaaataaaat tttgtcaatg atttgaacta
    13441 aatatagtgg tgttcttttg ttgtttttat atataaacac aatatatagt gtttgtattg
    13501 tgaaatagca atgattatcc tataaattgt ttttaaagaa actatatcct gtgttttgtt
    13561 atctaggata gaagattttc agcaagttat ctgaaaggaa attgaaggaa aatccagaaa
    13621 atgcttgaaa aaaatcctag aagatggtat aatactaaat tgtaagggtt atcacatata
    13681 actcaaaaaa agaaagaaca aaaggagagt caaactatgg cttctaaaga tttccacgta
    13741 gtggcagaaa caggtattca cgcacgtcca gcaacattgt tggtacaaac tgctagcaaa
    13801 tttgcttcag atatcactct tgagtacaaa ggtaaatcag ttaaccttaa atcaattatg
    13861 ggtgttatga gtcttggtgt tggccaaggt gctgacgtaa ctatctcagc tgaaggtgca
    13921 gatgcagatg acgctatcgc tgcaatctca gaaacaatgg aaaaagaagg attggcataa
    13981 gggaaatgac agaaatgctt aaaggaatcg cagcatctga cggtgttgca gttgcaaaag
    14041 catatctact cgttcagccg gatttgtcat ttgagactat tacagtcgaa gatacaaacg
    14101 cagaagaagc tcgccttgat gccgctctac aggcatcaca agacgagctt tctgttattc
    14161 gcgagaaagc agtaggtacg ctcggtgaag aagcagctca agtttttgat gctcacttaa
    14221 tggttcttgc tgacccagaa atgatcagcc aaatcaagga aactatccgt gcgaagaaag
    14281 tgaatgcaga agcaggtctg aaagaagtta cagatatgtt tatcactatc tttgaaggca
    14341 tggaagacaa cccatacatg caagaacgcg cagcggatat ccgcgacgtg acaaaacgtg
    14401 tattggcaaa ccttcttggt aaaaaattgc caaacccagc ttctattaat gaagaagtga
    14461 ttgtgattgc gcatgacttg acaccatctg atacagctca attggacaaa aactttgtaa
    14521 aagcttttgt aaccaacatt ggtggacgta caagccactc agctatcatg gcacgtacac
    14581 ttgaaattgc tgctgtatta ggtacaaata acatcactga aatcgttaaa gacggtgaca
    14641 tccttgctgt taacgggatc actggagaag tgattatcaa cccaacagat gaacaagcgg
    14701 cagaatttaa agcagctggt gaagcctatg cgaaacaaaa agctgaatgg gcacttttga
    14761 aagatgctca aacagtgact gctgacggta aacacttcga gttggctgcc aatattggta
    14821 ctccaaaaga cgttgaaggt gttaacaaca acggtgcaga agctgttgga ctttaccgta
    14881 cagagttctt gtacatggat tctcaagact tcccaactga agatgagcag tatgaagcat
    14941 acaaggctgt tcttgaagga atgaacggta aacctgttgt cgttcgtaca atggatatcg
    15001 gtggagataa ggaacttcct tacttcgata tgcctcacga aatgaaccca ttccttggat
    15061 tccgtgctct tcgtatctct atctctgaga ctggagatgc tatgttccgc acacaaatcc
    15121 gtgctcttct tcgtgcgtct gttcacggtc aattgcgtat catgttccca atggttgcgc
    15181 tcttgaaaga attccgtgca gcgaaagcag tctttgatga agaaaaagca aaccttcttg
    15241 ctgaaggtgt tgcagttgcg gataacatcc aagttggtat catgatcgag attcctgcag
    15301 cggctatgct tgcagaccaa tttgctaaag aagttgactt cttctcaatt ggtacaaacg
    15361 acttgatcca atatacaatg gcagcagacc gtatgaacga acaagtttca tacctttacc
    15421 aaccatacaa cccatcaatc ctacgcttga ttaacaatgt gatcaaagca gctcacgctg
    15481 aaggtaaatg ggctggtatg tgtggtgaga tggctggtga ccaacaagct gttccacttc
    15541 ttgtcggaat gggcttggat gagttctcta tgtcagcaac atctgtactt cgtacacgca
    15601 gcttgatgaa gaaactcgac acagctaaga tggaagagta cgcaaaccgt gcccttacag
    15661 aatgctcaac aatggaagaa gttcttgaac ttcaaaaaga atacgttaat tttgattaat
    15721 cgaaaagtcc ctgcaactca gttacaggga ctttttttga tattttaaaa agaattttca
    15781 agaaaatctt tcttataaaa agtccaacct tgaaaaagta gtggtcagaa caaaaaatac
    15841 ttaaatggtt cataaaattc ttgacaagtt ggagatttag gagtaaacta ttaaccagtt
    15901 aagtaataga gaggagtttc tgcaatttag aaatgaattg caactagaaa tatcaaatag
    15961 aaagagagtt tcgatgaaaa ttaataagaa ataccttgtt ggttctgcgg cagctttgat
    16021 tttaagtgtt tgttcttacg agttgggact gtatcaagct agaacggtta aggaaaataa
    16081 tcgtgtttcc tatatagatg gaaaacaagc gacgcaaaaa acggagaatt tgactcctga
    16141 tgaggttagc aagcgtgaag gaatcaatgc tgagcaaatc gtcatcaaga taacagacca
    16201 aggctatgtc acttcacatg gcgaccacta tcattattac aatggtaagg ttccttatga
    16261 tgcgattttc agtgaagaat tactcatgaa agatccaaac tataagctaa aagatgagga
    16321 tattgttaat gaggtcaagg gtggatatgt tatcaaggta gatggaaaat actatgttta
    16381 ccttaaggat gctgcccacg cggataacgt ccgtacaaaa gaggaaatca atcgacaaaa
    16441 acaagaacat agtcaacatc gtgaaggtgg gactccaaga aacgatggtg ctgttgcctt
    16501 ggcacgttcg caaggacgct atactacaga tgatggttat atctttaatg cttctgatat
    16561 catagaggat actggtgatg cttatatcgt tcctcatgga gatcattacc attacattcc
    16621 taagaatgag ttatcagcta gcgagttggc tgctgcagaa gccttcctat ctggtcgggg
    16681 aaatctgtca aattcaagaa cctatcgccg acaaaatagc gataacactt caagaacaaa
    16741 ctgggtacct tctgtaagca atccaggaac tacaaatact aacacaagca acaacagcaa
    16801 cactaacagt caagcaagtc aaagtaatga cattgatagt ctcttgaaac agctctacaa
    16861 actgcctttg agtcaacgac atgtagaatc tgatggcctt gttttcgacc cagcgcaaat
    16921 cacaagtcga acagctagag gtgttgcagt gccacacgga gatcattacc acttcatccc
    16981 ttactctcaa atgtctgaat tggaagaacg aatcgctcgt attattcccc ttcgttatcg
    17041 ttcaaaccat tgggtaccag attcaaggcc agaacaacca agtccacaac cgactccgga
    17101 acctagtcca ggcccgcaac ctgcaccaaa tcttaaaata gactcaaatt cttctttggt
    17161 tagtcagctg gtacgaaaag ttggggaagg atatgtattc gaagaaaagg gcatctctcg
    17221 ttatgtcttt gcgaaagatt taccatctga aactgttaaa aatcttgaaa gtaagttatc
    17281 aaaacaagag agtgtttcac acactttaac tgctaaaaaa gaaaatgttg ctcctcgtga
    17341 ccaagaattt tatgataaag catataatct gttaactgag gctcataaag ccttgtttga
    17401 aaataagggt cgtaattctg atttccaagc cttagacaaa ttattagaac gcttgaatga
    17461 tgaatcgact aataaagaaa aattggtaga tgatttattg gcattcctag caccaattac
    17521 ccatccagag cgacttggca agccaaattc tcaaattgag tatactgaag acgaagttcg
    17581 tattgctcaa ttagctgata agtatacaac gtcagatggt tacatttttg atgaacatga
    17641 tataatcagt gatgaaggag atgcatatgt aacgcctcat atgggccata gtcactggat
    17701 tggaaaagat agcctttctg ataaggaaaa agttgcagct caagcctata ctaaagaaaa
    17761 aggtatccta cctccatctc cagacgcaga tgttaaagca aatccaactg gagatagtgc
    17821 agcagctatt tacaatcgtg tgaaagggga aaaacgaatt ccactcgttc gacttccata
    17881 tatggttgag catacagttg aggttaaaaa cggtaatttg attattcctc ataaggatca
    17941 ttaccataat attaaatttg cttggtttga tgatcacaca tacaaagctc caaatggcta
    18001 taccttggaa gatttgtttg cgacgattaa gtactacgta gaacaccctg acgaacgtcc
    18061 acattctaat gatggatggg gcaatgccag tgagcatgtg ttaggcaaga aagaccacag
    18121 tgaagatcca aataagaact tcaaagcgga tgaagagcca gtagaggaaa cacctgctga
    18181 gccagaagtc cctcaagtag agactgaaaa agtagaagcc caactcaaag aagcagaagt
    18241 tttgcttgcg aaagtaacgg attctagtct gaaagccaat gcaacagaaa ctctagctgg
    18301 tttacgaaat aatttgactc ttcaaattat ggataacaat agtatcatgg cagaagcaga
    18361 aaaattactt gcgttgttaa aaggaagtaa tccttcatct gtaagtaagg aaaaaataaa
    18421 ctaatgaaaa atgaaagtct cgataaagag gctttcattt ttattatgta tatatgtaaa
    18481 attcttgaca agcaatatta aaaagagtaa actattaact agttaattaa ccggtttatt
    18541 actttatagt gaatcaaata tacttaagaa aagaggaaag aatgaaaatc aataaaaaat
    18601 atctagctgg gtcagtagct acacttgttt taagtgtctg tgcttatgaa ctaggtttgc
    18661 atcaagctca aactgtaaaa gaaaataatc gtgtttccta tatagatgga aaacaagcga
    18721 cgcaaaaaac ggagaatttg actcctgatg aggttagcaa gcgtgaagga atcaatgccg
    18781 aacaaatcgt catcaagata acagaccaag gctatgtcac ttcacatggg gaccactatc
    18841 attattacaa tggtaaggtt ccttatgacg ctatcatcag tgaagaattg ctgatgaagg
    18901 atccaaacta ccagctaaag gacgaggata ttatcagtga aatcaagggt ggttatgtga
    18961 ttaaggtaga tggaaaatac tatgtttacc ttaaggatgc agctcatgcg gataatgtcc
    19021 gtacaaaaga agaaatcaat cggcaaaaac aagaacatag tcagcatcgt gaaggaggga
    19081 cttcaacaaa cgatggtgcg gtagcctttg cacgttcaca aggacgctat actacagatg
    19141 atggttatat ctttaatgct tctgatatca ttgaggacac gggtgatgct tatatcgttc
    19201 ctcacggcga ccattaccat tacattccta agaatgagtt atcagctagc gagttagctg
    19261 ctgcagaagc cttcctatct ggtcggggaa atctgtcaaa ttcaagaacc tatcgccgac
    19321 aaaatagcga taacacttca agaacaaact ggctaccttc tgtaagcaat ccaggaacta
    19381 caaatactaa cacaagcaac aacagcaaca ctaacagtca agcaagtcaa agtaatgaca
    19441 ttgatagtct cttgaaacag ctctacaaac tgcctttgag tcaacgccat gtagaatctg
    19501 atggccttgt tttcgaccca gcgcaaatca caagtcgaac cgccagaggt gtagctgtcc
    19561 ctcatggtaa ccattaccac tttatccctt atgaacaaat gtctgaattg gaaaaacgaa
    19621 ttgctcgtat tattcccctt cgttatcgtt caaaccattg ggtaccagat tcaagaccag
    19681 aacaaccaag tccacaatcg actccggaac ctagtccaag tctgcaacct gcaccaaatc
    19741 ctcaaccagc tccaagcaat ccaattgatg agaaattggt caaagaagct gttcgaaaag
    19801 taggcgatgg ttatgtcttt gaggagaatg gagtttctcg ttatatccca gccaaggatc
    19861 tttcagcaga aacagcagca ggcattgata gcaaactggc caagcaggaa agtttatcgc
    19921 ataagctagg agctaagaaa actgacctcc catctagtga tagagaattt tacaataaga
    19981 cttatgactt actagcaaga attcaccaag atttacttga taataaaggt cgacaagttg
    20041 attttgaggc tttggataac ctgttggaac gactcaagga tgtctcaagt gataaagtca
    20101 agttagtgga tgatattctt gccttcttag ctccgattcg tcatccagaa cgtttagg
//
LOCUS       DAVBEO010000042        20106 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 009
            SAMEA1678075-rid20185393.denovo.042, whole genome shotgun sequence.
ACCESSION   DAVBEO010000042 DAVBEO010000000
VERSION     DAVBEO010000042.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678075
            Sequence Read Archive: ERR226392
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 20106)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20106)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980207.1
            Genome Coverage       :: 150x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:50:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 72 of 147
            Pseudo Genes (incomplete)         :: 72 of 147
            Pseudo Genes (internal stop)      :: 42 of 147
            Pseudo Genes (multiple problems)  :: 32 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20106
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678075-rid20185393.denovo.042"
                     /strain="KS 009"
                     /db_xref="taxon:1313"
     gene            complement(20..667)
                     /locus_tag="VQ543_001536"
     CDS             complement(20..667)
                     /locus_tag="VQ543_001536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000345255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HET2612239.1"
                     /translation="MDFEYFYNREAERFNFLKVPEILVDREEFRGLSAEAIILYSILL
                     KQTGMSFKNNWIDKEGRVFIYFTVEEIMKRRNISKPTAIKTLDELDVKKGIGLIERVR
                     LGLGKPNIIYVKDFMSIFQVKENDLQKSKNLTSEVKDFNLRSKENELQEVKNLDSNYI
                     ENNKSKYSKREYSFGENGLGTFQNVFLAAEDISDLQIIMNSQLENYIRLPAKLES"
     gene            complement(776..1294)
                     /locus_tag="VQ543_001537"
     CDS             complement(776..1294)
                     /locus_tag="VQ543_001537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013852041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClbS/DfsB family four-helix bundle protein"
                     /protein_id="HET2612240.1"
                     /translation="MRTYENKEELKAEIEKTFEKYILEFDNIPENLKDKRADEVDRTP
                     AENLAYQVGWTNLVLKWEEDERKGLQVKTPSDKFKWNQLGELYQWFTDTYAHLSLQEL
                     KAKLNENINSISAMIDSLSEEELFEPHMRKWADEATKTATWEVYKFIHVNTVAPFGTF
                     RTKIRKWKKIVL"
     gene            complement(1521..2390)
                     /gene="rsmI"
                     /locus_tag="VQ543_001538"
     CDS             complement(1521..2390)
                     /gene="rsmI"
                     /locus_tag="VQ543_001538"
                     /EC_number="2.1.1.198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001166894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (cytidine(1402)-2'-O)-methyltransferase"
                     /protein_id="HET2612241.1"
                     /translation="MQIQKSFKGQSPYGKLYLVATPIGNLDDMTFRAIQTLKEVDWIA
                     AEDTRNTGLLLKHFDISTKQISFHEHNAKEKIPDLIGFLKAGQSIAQVSDAGLPSISD
                     PGHDLVKAAIEEEIAVVTVPGTSAGISALIASGLAPQPHIFYGFLPRKSGQQKQFFGS
                     KKDYPETQIFYESPHRVADTLENMLEVYGDRSVVLVRELTKIYEEYQRGTISELLESI
                     AETPLKGECLLIVEGASQDVEEKDEEDLFLEIQARIQQGMKKNQAIKEVAKIYQWNKS
                     QLYAAYHDWEEKQ"
     gene            complement(2393..2710)
                     /gene="yabA"
                     /locus_tag="VQ543_001539"
     CDS             complement(2393..2710)
                     /gene="yabA"
                     /locus_tag="VQ543_001539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication initiation control protein YabA"
                     /protein_id="HET2612242.1"
                     /translation="MDKKELFDALDDFSQQLLVTLADVEAIKKNLKSLVEENTALRLE
                     NSKLRERLGEVEADAPVKAKHVRESVRRIYRDGFHVCNDFYGQRREQDEECMFCDELL
                     YRE"
     gene            complement(2750..3640)
                     /locus_tag="VQ543_001540"
     CDS             complement(2750..3640)
                     /locus_tag="VQ543_001540"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000806705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta'"
                     /protein_id="HET2612243.1"
                     /translation="MKQDQLKAWQPAQFDRFVRILEQDQLNHAYLFSGFFGSLEMAQF
                     LAKSLFCTDKVGVLPCEKCRSCKLIEQEEFPDVTLIKPVNQVIKTERIRELVGQFSQA
                     GIESQQQVFIIEQADKMHPNAANSLLKVIEEPQSEVYIFFLTSDEEKMLPTIRSRTQI
                     FHFKKQEEKLILLLEQMGLVKKKATLLAKFSQSRAEAEKLANQASFWTLVDESERLLT
                     WLVAKKKESYLQVAKLANLADDKEKQDQVLRILEVLCGQDLLQVRVRVILQDLLEARK
                     MWQANVSFQNAMEYLVLKEI"
     gene            complement(3637..4275)
                     /locus_tag="VQ543_001541"
     CDS             complement(3637..4275)
                     /locus_tag="VQ543_001541"
                     /EC_number="2.7.4.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTMP kinase"
                     /protein_id="HET2612244.1"
                     /translation="MSKGFLVSLEGPEGAGKTSVLEALLPILEEKGVKVLTTREPGGV
                     LIGEKIREVILDPSHTQMDAKTELLLYIASRRQHLVEKVLPALEAGKLVIMDRFIDSS
                     VAYQGFGRGLDIEAIDWLNQFATDGLKPDLTLYFDIEVEEGLARIAANSDREVNRLDL
                     EGLDLHKKVRQGYLSLLDKEGNRIVKIDASLPLEQVVETTKAVLFDGMGLAK"
     gene            complement(4495..5292)
                     /gene="proC"
                     /locus_tag="VQ543_001542"
     CDS             complement(4495..5292)
                     /gene="proC"
                     /locus_tag="VQ543_001542"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HET2612245.1"
                     /translation="MKIGFIGLGNMGASLTKSVLQARPSDEILLANRSQVKVDAFIAN
                     FGGQTSNNEEIFEEADVIFLGVKPAQFSELLSQYQTILEKRESLLLISMAAGLTLEKL
                     ASLIPSQHRIIRMMPNTPASIGQGVISYALSPNCRAEDSEIFCQLLAKAGLLVELGES
                     LINAATGLAGCGPAFVYLFIEALADAGVQTGLPRETALKMAAQTVVGAGQLVLESQQH
                     PGVLKDQVCSPGGSTIAGVASLEAHAFRGTVMEAVHQAYKRTQELGK"
     gene            complement(5296..6558)
                     /locus_tag="VQ543_001543"
     CDS             complement(5296..6558)
                     /locus_tag="VQ543_001543"
                     /EC_number="1.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate-5-semialdehyde dehydrogenase"
                     /protein_id="HET2612246.1"
                     /translation="MVSRQEQFEQVQAVKKSINTASEEVKNQALLAMADHLVAATEEI
                     LAANALDMAAAKGKISDVMLDRLYLDADRIEAMARGIREVVALPDPIGEVLETSQLEN
                     GLVITKKRVAMGVIGIIYESRPNVTSDAAALTLKSGNAVVLRSGKDAYQTTHAIVTAL
                     KKGLETTTIHPNVIQLVEDTSRESSYAMMKAKGYLDLLIPRGGAGLINAVVENAIVPV
                     IETGTGIVHVYVDKDADEDKALSIINNAKTSRPSVCNAMEVLLVHENKAVSFLPRLEQ
                     VLVADRKEAGLEPIQFRLDSKASQFVSGQAAQAQDFDTEFLDYILAVKVVSSLEEAVA
                     HIESHSTHHSDAIVTENAEAAAYFTDQVDSAAVYVNASTRFTDGGQFGLGCEMGISTQ
                     KLHARGPMGLKELTSYKYVVTGDGQIRE"
     gene            complement(6568..7698)
                     /locus_tag="VQ543_001544"
     CDS             complement(6568..7698)
                     /locus_tag="VQ543_001544"
                     /EC_number="2.7.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004240022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate 5-kinase"
                     /protein_id="HET2612247.1"
                     /translation="MNNRSETMKYKRIVFKVGTSSLTNEDGSLSRSKVKDITQQLAML
                     HEAGHELILVSSGAIAAGFGALGFKKRPTKIADKQASAAVGQGLLLEEYTTNLLLRQI
                     VSAQILLTQDDFVDKRRYKNAHQALSVLLNRGAIPIINENDSVVIDELKVGDNDTLSA
                     QVAAMVQADLLVFLTDVDGLYTGNPNSDPRAKRLERIETINREIIDMAGGAGSSNGTG
                     GMLTKIKAATIATESGVPVYICSSLKSDSMVEAAEETEDGSYFVAQEKGLRTQKQWLA
                     FYAQSQGSIWVDKGAAEALSQHGKSLLLSGIVEAEGVFSYGDIVTVFDKESGKSLGKG
                     RVQFGASALEDMLRFQKAKGVLIYRDDWISITPEIQLLFTEF"
     gene            complement(7781..9661)
                     /gene="cbpE"
                     /locus_tag="VQ543_001545"
                     /gene_synonym="pce"
     CDS             complement(7781..9661)
                     /gene="cbpE"
                     /locus_tag="VQ543_001545"
                     /gene_synonym="pce"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine esterase CbpE"
                     /protein_id="HET2612248.1"
                     /translation="MKKKLTSLALVGAFLGLSWYGNVQAQESSGNKIHFINVQEGGSD
                     AIILESNGHFAMVDTGEDYDFPDGSDSRYPWREGIETSYKHVLTDRVFRRLKELGVQK
                     LDFILVTHTHSDHIGNVDELLSTYPVDRVYLKKYSDSRITNSERLWDNLYGYDKVLQT
                     AAEKGVSVIQNITQGDAHFQFGDMDIQLYNYENETDSSGELKKIWDDNSNSLISVVKV
                     NGKKIYLGGDLDNVHGAEDKYGPLIGKVDLMKFNHHHDTNKSNTKDFIKNLSPSLIVQ
                     TSDSLPWKNGVDSEYVNWLKERGIERINAASKDYDATVFDIRKDGFVNISTSYKPIPS
                     FQAGWHKSAYGNWWYQAPDSTGEYAVGWNEIEGEWYYFNQTGILLQNQWKKWNNHWFY
                     LTDSGASAKNWKKIDGIWYYFNKENQMEIGWVQDKEQWYYLDVDGSMKTGWLQYKGQW
                     YYFAPSGEMKTGWVKDKEAWYYMDSTGIMKTGEIEVAGHHYYLEESGAMKQGWLKKAN
                     DWYFYKTGGSRAIGWIKDKDKWYFLKENGQLLVNGKTPEGYTVDSSGAWLVDVPIEKS
                     ATIKTTSHSEIKESKEVVKKDLENKETSQHESVTNSSTSQDLTSSTSQSSETSVNKSE
                     SE"
     gene            complement(9664..10551)
                     /locus_tag="VQ543_001546"
     CDS             complement(9664..10551)
                     /locus_tag="VQ543_001546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HET2612249.1"
                     /translation="MEIKIETGGLRLDKALSDLSELSRSLANEQIKSGQVLVNGQVKK
                     AKYTVQEGDVVTYHVPEPEVLEYVAEDLPLEIVYQDEDVAVVNKPQGMVVHPSAGHTS
                     GTLVNALMYHIKDLSGINGVLRPGIVHRIDKDTSGLLMIAKNDDAHLVLAQELKDKKS
                     LRKYWAIVHGNLPNDRGVIEAPIGRSEKDRKKQAVTAKGKPAVTRFHVLERFGDYSLV
                     ELQLETGRTHQIRVHMAYIGHPVAGDEVYGPRKTLKGHGQFLHAKTLGFTHPRTGKTL
                     EFKADIPEIFKETLERLRK"
     gene            complement(10541..11002)
                     /locus_tag="VQ543_001547"
     CDS             complement(10541..11002)
                     /locus_tag="VQ543_001547"
                     /EC_number="3.4.23.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HET2612250.1"
                     /translation="MKKRAIVAVIVLLLIGLDQLVKSYIVQQIPLGEVRSWIPNFVSL
                     TYLQNRGAAFSILQDQQLLFAVITLVVVIGAIWYLHKHMEDSFWMFLGLTLIIAGGLG
                     NFIDRVSQGFVVDMFHLDFINFAIFNVADSYLTVGVIILLIAMLKEEINGN"
     gene            complement(10999..11907)
                     /locus_tag="VQ543_001548"
     CDS             complement(10999..11907)
                     /locus_tag="VQ543_001548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001025716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HET2612251.1"
                     /translation="MNIQQLRYVVAIANSGTFREAAEKMYVSQPSLSISVRDLEKELG
                     FKIFRRTSSGTFLTRRGMEFYEKAQELVKGFDIFQNQYANPEEEKDEFSVASQHYDFL
                     PPTITAFSERYPDYKNFRIFESTTVQILDEVAQGHSEIGIIYLNNQNKKGIMQRVEKL
                     GLEVIELIPFHTHIYLCEGHPLAQKEELVMEDLADLPTVRFTQEKDEYLYYSENFVDT
                     SASSQMFNVTDRATLNGILERTDAYATGSGFLDSDSVNGITVIRLKDNLDNRMVYVKR
                     EEVELSQAGTLFVEVMQEYFDQKRKS"
     gene            11900..12097
                     /locus_tag="VQ543_001549"
     CDS             11900..12097
                     /locus_tag="VQ543_001549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET2612252.1"
                     /translation="MFIFYPQLLYLFIIPYFRSFPKRKKEHPILLNYLHYLPFSRQSY
                     FQNQFKKISGYTPLQYRKEKR"
     gene            complement(12149..12820)
                     /locus_tag="VQ543_001550"
     CDS             complement(12149..12820)
                     /locus_tag="VQ543_001550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET2612253.1"
                     /translation="MKKRAIQILLALSLIFYKSTWFWRVFNHLAKPYLPASREFFQIL
                     LLMESGVLFLAVIYLLVFAGKKIFHFKWQLRYFIYLLLGYIISYMSDFLFSYFISLSS
                     NQISLNETVEMMGRQEFPYFLLIVCFIAPIAEELIYRGVLMTTFFKNSPWYGDVLLSA
                     IIFGYIHINFALTPLAFFIYASGGLILALLYRMTKNLYYPILVHILINITAFWDVWLL
                     LFSGS"
     gene            complement(12874..13095)
                     /locus_tag="VQ543_001551"
     CDS             complement(12874..13095)
                     /locus_tag="VQ543_001551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000602450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SP_0924 family bacteriocin-like peptide"
                     /protein_id="HET2612254.1"
                     /translation="MILMTKNINLTNEELELIQGGADSYGKNPNGRYDWEIEPVLTLP
                     VHGFCPRGTYDLGYIGGGNHLCKGSAARF"
     gene            13367..14176
                     /locus_tag="VQ543_001552"
     CDS             13367..14176
                     /locus_tag="VQ543_001552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000593565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HET2612255.1"
                     /translation="MIKLLALDMDGTLLNEAKEIPQAHITAIHKAIEKGVKLVLCTGR
                     PLFGVLPYYKKLGLDLQNEYVIVNNGCSTHQTSDWGLVDWQELSPADIEYLYDLAEKS
                     DVQLTLFDESHYFVLGGKPNQVIENDAKLVFSDLTEISLEEATSGKFRMFQGMFLGTK
                     EQTDDFEQRFAEELCQRFSGVRSQPVIYEAMPLGTTKATALSRLAEILKIDSSEIMAM
                     GDANNDIEMLQFAGLGIAMGNASDYVKSLADAVTSSNEEDGVARAIEKYIL"
     gene            complement(14357..15232)
                     /gene="aguB"
                     /locus_tag="VQ543_001553"
     CDS             complement(14357..15232)
                     /gene="aguB"
                     /locus_tag="VQ543_001553"
                     /EC_number="3.5.1.53"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001246759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-carbamoylputrescine amidase"
                     /protein_id="HET2612256.1"
                     /translation="MRNVRVATIQMQCAKDVATNIQTAERLVRQAAEQGAQIILLPEL
                     FEHPYFCQERQYDYYQYAQSVAENTAIQHFKLLAKELQVVLPISFYEKDGNVLYNSIA
                     VIDADGEVLGVYRKTHIPDDHYYQEKFYFTPGNTGFKVWNTRYAKIGIGICWDQWFPE
                     TARCLALNGAELLFYPTAIGSEPILDTDSCGHWQRTMQGHAAANIVPVIAANRYGLEE
                     VTPSEENGGQSSSLDFYGSSFMTDETGAILERAERQEEAVLLATYNLDKGASERLNWG
                     LFRDRRPEMYRQITD"
     gene            complement(15242..16327)
                     /gene="aguA"
                     /locus_tag="VQ543_001554"
     CDS             complement(15242..16327)
                     /gene="aguA"
                     /locus_tag="VQ543_001554"
                     /EC_number="3.5.3.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="agmatine deiminase"
                     /protein_id="HET2612257.1"
                     /translation="MMDSPKKLGYHMPAEYEPHHGTLMIWPTRPGSWPFQGKAAKRAF
                     TQIIETIAEGERVYLLVEQAYLSEAQSYLGDKVVYLDIPTNDAWARDTGPTILVNDKG
                     KKLAVDWAFNAWGGTYDGLYQDYEEDDQVASRFAEALERPVYDAKPFVLEGGAIHSDG
                     QGTILVTESCLLSPGRNPNLTKEEIENTLLESLGAEKVIWLPYGIYQDETNEHVDNVV
                     AFVGPAEVVLAWTDDENDPQYAMSKADLELLEQETDAKGCHFTIHKLPIPAVRQVVTE
                     EDLPGYIYEEGEEERYAGERLAASYVNFYIANKAVLVPQFEDVNDQVALDILSKCFPD
                     RKVVGIPARDILLGGGNIHCITQQIPE"
     gene            complement(16324..17451)
                     /gene="nspC"
                     /locus_tag="VQ543_001555"
     CDS             complement(16324..17451)
                     /gene="nspC"
                     /locus_tag="VQ543_001555"
                     /EC_number="4.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxynorspermidine decarboxylase"
                     /protein_id="HET2612258.1"
                     /translation="MKLEQVPTPAYVIDLAKLEANCRILQYVQEEAGCKVLLAQKAYS
                     LYKTYPLISQYLSGTTASGLYEAKLAREEFPGEVHVFAPAFKDEDMEELLGITDHIVF
                     NSERQLRKHGARCREAGVSVGLRLNPQCSTQGDHALYDPCAPGSRFGVTIDKIPSDLL
                     DLVDGLHFHTLCEQGADDLQTTLKAVEEQFGPYLHEVKWLNMGGGHHITREGYDVDLL
                     ISEIKRIRKTYNLEIYIEPGEAIALNAGYLATEVLDIVENGMEILVLDASATCHMPDV
                     LEMPYRPPLRNGFESQEKAHTYRLSSNTCLTGDVIGDYSFENPVQIGDRLYFQDMAIY
                     SFVKNNTFNGIGLPSLYLMDEQGDCSLLKAFGYQDFKGRLS"
     gene            complement(17451..18710)
                     /locus_tag="VQ543_001556"
     CDS             complement(17451..18710)
                     /locus_tag="VQ543_001556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000088792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="saccharopine dehydrogenase family protein"
                     /protein_id="HET2612259.1"
                     /translation="MSRLLVIGCGGVAQVAISKICQDSETFTEIMIASRTKSKCDDLK
                     AKLEGKTSTKIETAALDADKVEEVIALIESYKPEAVLNVALPYQDLTIMDACLATGVH
                     YIDTANYEAEDTEDPEWRAIYEKRCKELGFTAYFDYSWQWAYQEKFKEAGLTALLGSG
                     FDPGVTSVFSAYALKHYFDEIHYIDILDCNGGDHGYPFATNFNPEINLREVSAPGSYW
                     EDGKWVEVEAMSIKREYDFPQVGQKDMYLLHHEEIESLAKNIPGVKRIRFFMTFGQSY
                     LTHMKCLENVGLLRTDTINFNGQEIVPIQFLKALLPDPASLGPRTVGKTNIGCIFTGV
                     KDGVEKTIYIYNVCDHQECYAEVGSQAISYTTGVPAMIGTKLVMNGTWKQAGVYNLEE
                     LDPDPFMEALNEYGLPWVVVENPQMLD"
     gene            complement(18707..19567)
                     /gene="speE"
                     /locus_tag="VQ543_001557"
     CDS             complement(18707..19567)
                     /gene="speE"
                     /locus_tag="VQ543_001557"
                     /EC_number="2.5.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyamine aminopropyltransferase"
                     /protein_id="HET2612260.1"
                     /translation="MDLWFSEVHTPDVKLSLRTAKQLYAGKSEWQDIEVLDTPAFGKI
                     LILNGHVLFSDADDFVYNEMTVHVPMAVHPNPKKVLVIGGGDGGVAQVLTLYPELEQI
                     DIVEPDEMLVEVCREYFPDFAAGLDDPRVTIYYQNGLRFLRNCEYDYDIIINDATDPF
                     GHTEGLFTKEFYGNSYRALKEDGIMIYQHGSPFFDEDESACRSMHRKVNQAFPISRVY
                     QAHIPTSPAGYWLFGFASKKYHPVKDFDKEGWKKRQLFTEYYTANLHVGAFMLPKYVE
                     DILEEEEGKK"
     gene            19823..20106
                     /locus_tag="VQ543_001558"
                     /pseudo
     CDS             19823..20106
                     /locus_tag="VQ543_001558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019770457.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         5835 a         4619 c         3573 g         6079 t
ORIGIN      
        1 tggtattatc aatcatgaac taggattcta gttttgcagg aagtctaatg taattctcaa
       61 gctgtgagtt cattatgatt tgtaaatccg atatatcttc agcagctaaa aacacatttt
      121 gaaatgttcc aagtccgttt tcaccaaaac tatattctct cttactatac ttactcttat
      181 tattctctat atagttagag tcaaggttct taacctcttg aagttcattt tctttacttc
      241 tgaggttaaa atcttttact tctgaagtta agttttttga cttctgtaag tcattttctt
      301 ttacctgaaa tatactcata aagtctttaa cataaatgat gttcggctta ccaagtccaa
      361 gccttactct ttcgatcagt cctattcctt tttttacatc aagctcatct aatgttttta
      421 tggcagttgg ctttgagata tttcttcttt tcataatttc ttcgacagta aaatagataa
      481 atactctgcc ttccttgtct atccagttat tcttaaatga cattcctgtc tgtttaagaa
      541 gtatggaata aaggataatt gcttctgctg ataagccccg aaattcttct ctatcaacta
      601 atatctccgg tacttttaag aagttaaatc tttccgcttc tctgttataa aaatattcaa
      661 agtccatgca agatcacctc ccttcttaaa aatttgcaaa gaaaaagacg atagtttttc
      721 ttctatcgcc tttggtaacc atttttatga aattttttaa agttaaaaat ataatttata
      781 atactatctt cttccatttt ctgattttag ttctgaaagt tccaaaaggt gcaaccgtat
      841 ttacatgaat aaacttatac acttcccaag tcgctgtttt agtcgcttca tcagcccact
      901 ttctcatatg cggttcaaat aattcttcct cactcaacga atcaatcatt gcagagatag
      961 aattaatatt ttcatttaat tttgctttca actcttgcag agataaatga gcgtaggtat
     1021 ctgtgaacca ctgatataat tcaccaagtt gattccattt aaatttatcc gatggtgttt
     1081 ttacttgaag cccctttctt tcatcttctt cccatttaag aaccaagttg gtccaaccaa
     1141 cctgataagc aaggttttct gctggagttc tgtcaacttc atcagctctc ttatctttta
     1201 aattttctgg aatattatca aattctaaaa tatatttctc aaatgttttc tctatctcag
     1261 cttttagttc ttctttattt tcgtatgttc gcaaaaaatc accttctttc tgatttatca
     1321 atcctttgat ttaaaatgac cttatttttc tatttatacc ttctaagaac gctataactg
     1381 ctgctccaaa catcggtatt ccgtatgggc ttaataaaaa acttaatacc aaagcttcta
     1441 taccaagtga tacatcttta tattatcatc actaattaag ttaaacagaa acagacagaa
     1501 ttattacatc ctgtctccct ttattgtttt tcttcccaat cgtggtaggc agcgtagagt
     1561 tgactcttat tccactggta aatcttagct acttccttaa tagcttgatt tttcttcatg
     1621 ccttgctgga tacgggcttg gatttctaag aacaagtcct cctcgtcttt ttcctccaca
     1681 tcctgactgg caccttcaac aataagaagg cattcgccct tgagtggcgt ttcagcgatg
     1741 ctttccagta attcagaaat tgtacctcgt tggtattctt catagatttt ggtcaattcc
     1801 ctgaccaaaa caaccgagcg gtcaccgtag acttctaaca tattttccaa cgtgtctgct
     1861 acacgatgag gtgattcata aaaaatctgt gtttcaggat aatctttttt agagccaaaa
     1921 aattgcttct gttgacctga ttttctcggt aaaaaaccgt aaaagatatg tggctgtggc
     1981 gctaaaccac tggcaatcaa ggcagaaatt cctgcagagg tacctggaac agtcacaact
     2041 gcaatttctt cctcaatagc tgccttaact aaatcatgac cagggtctga aatgctaggc
     2101 aaaccggcat cagagacctg agcaatactt tgccctgctt tcaagaaacc aatcaaatca
     2161 ggaatttttt ccttggcatt gtgctcatga aaactgatct gcttggtgga aatgtcaaaa
     2221 tgcttgagca aaagccctgt attgcgcgta tcctcagcag caatccagtc cacttctttc
     2281 aaggtctgga tagcacgaaa agtcatatca tctagattgc caatcggcgt tgccactaga
     2341 tacagcttgc catagggaga ctgcccctta aaactttttt gaatttgcat gcttactccc
     2401 tgtataacaa ctcatcacag aacatacatt cttcgtcctg ctctcgacgt tgtccataaa
     2461 aatcattaca tacgtgaaat ccatcacggt aaatacgacg gacactttcg cgaacatgct
     2521 tggccttgac gggagcgtct gcttccacct cacccaagcg ttctcgcaac ttactatttt
     2581 ccaagcgaag agctgtattt tcttctacca agctcttgag atttttcttg atggcttcca
     2641 catcggctaa agttaccaat aattgttggg aaaaatcatc cagcgcgtca aataattctt
     2701 ttttgtccat aaaacagccc tttcctttct ttatcattca tttttgagtt tatatttctt
     2761 tcaagaccag atattccatg gcattttgaa agctgacatt agcttgccac atttttctag
     2821 cttctagtaa atcttgtaga atcactctta ctcttacctg caagaggtcc tgcccacaga
     2881 gaacttcaag aatccgtaaa acctgatcct gtttttcctt atcatctgcc aagttggcta
     2941 atttggcaac ctgtagataa ctttcttttt tcttagctac taaccaagtc agcaggcgtt
     3001 cactttcatc gaccaaggtc caaaaacttg cctgattagc caacttttct gcttcagctc
     3061 gcgattgact aaacttagct aaaagagtcg cttttttctt aacaagtccc atttgttcta
     3121 agagtaagat aagtttttct tcttgctttt taaagtggaa gatctgagtc cgacttcgga
     3181 ttgtcggtaa catcttttcc tcatcgctag tcaagaagaa aatataaact tcactctggg
     3241 gttcttcgat gaccttgagc agagaattgg ctgcgttggg atgcatttta tccgcttgct
     3301 cgatgataaa gacctgttgc tggctttcaa tccctgcttg agaaaactgt cccaccaatt
     3361 cccgaatacg ttctgtcttg atgacctgat tgactggctt aatcaaggtg acatctggaa
     3421 actcttcctg ttcaatcagc ttgcaacttc ggcatttctc acatggtaag acgccaactt
     3481 tatccgtaca aaagaggctc ttagctaaaa attgcgccat ttccaagctt ccaaagaaac
     3541 ctgaaaagag ataggcgtga ttgagctggt cttgttctaa gatacggaca aaacggtcaa
     3601 actgagctgg ttgccaagcc tttagttgat cttgtttcat ttggccaagc ccattccgtc
     3661 aaacaagaca gccttggtag tttccacaac ttgctccaaa gggagactag catcaatctt
     3721 gacaatgcga tttccctctt tatccagaag agaaaggtag ccttgacgaa cttttttatg
     3781 caagtccaac ccttccaaat ccaaacgatt aacctcgcgg tcactattag cagcaatacg
     3841 agccagccct tcttccacct cgatgtcaaa atagagtgtc aaatcgggtt tgaggccatc
     3901 tgtcgcaaac tgattgagcc agtcaatggc ttcaatatct aagccacgac caaatccctg
     3961 ataggcaaca gaactatcga taaaacgatc catgatgacc aacttgccag cttcaagggc
     4021 tggaagaact ttttccacca aatgctgtct gcgactggca atatagagaa gtagctctgt
     4081 tttagcatcc atctgagtat gacttggatc caaaatcact tcccgaatct tctccccaat
     4141 caagactccg ccaggttcac gggtcgtcag cacctttact cctttttcct ctaaaattgg
     4201 tagcagagcc tctaaaacac tggtcttgcc tgctccctct ggtccctcaa gagagactaa
     4261 aaatcctttt gacatgtcta actcatttct tttttactac ttctattcta tcaaaaaaat
     4321 aggggtttgt gacaatcttt ttgtcttctc atttcatact caatgaaaat caaagagcaa
     4381 actaggaagc tagccgcagg ctgtacttga gtacggcaag gtgaagctga cgcagtttga
     4441 atttgatttt cgaagagtat cagccaccat aaaagaggca gataaaacta cctcttattt
     4501 acctagttct tgtgttcgtt tataggcttg atgaactgcc tccatgactg tgcctcgaaa
     4561 agcatgcgct tctaggcttg ctacgccagc aatagtcgaa ccgcctggac tacaaacttg
     4621 atctttcaaa actccaggat gttgctggct ttctaggacc aattgcccag ctcctaccac
     4681 agtttgggct gccattttca aggctgtttc tcgtggtaat cccgtctgaa cacctgcatc
     4741 tgccaaggcc tcaataaaga gatagacaaa ggctggtcca caacctgcaa gacctgtcgc
     4801 tgcattgatt aagctttctc ctaattcaac caagagacca gccttggcta aaagctgaca
     4861 aaagatctca ctgtcctcag ccctgcaatt aggagacaag gcataactaa tcactccttg
     4921 cccgatagaa gcaggggtat taggcatcat acgaataatt cggtgttggc ttgggataag
     4981 acttgctagt ttttctaagg tcaatccagc tgccatcgaa atcaaaagaa gactttctct
     5041 tttttcaagg atggtctggt attgagaaag cagttcagaa aactgagcag gcttaacacc
     5101 tagaaaaatc acatctgctt cttcgaatat ttcttcattg ttagaagtct gaccaccgaa
     5161 gttagcgatg aaagcatcca ccttgacttg actacgattg gcaaggagaa tctcatctga
     5221 cggtctagcc tgcaagacag acttggttaa actagcaccc atattcccca aaccgataaa
     5281 tccaatcttc atctcttact cccttatctg tccatcacca gtgaccacat acttgtagct
     5341 agtcaattcc ttcaagccca taggaccacg cgcgtgcaat ttctgagtag aaatccccat
     5401 ttcacaacca agaccaaatt gtcctccatc tgtgaaacga gttgaggcat taacatacac
     5461 cgctgcagag tccacttgat ctgtaaagta tgctgcagct tcagcatttt ccgtcacaat
     5521 ggcatccgaa tgatgggtac tgtgggattc aatatgcgca accgcttctt ctaaactgct
     5581 cacaacctta acagctagaa tatagtctaa aaactcggta tcaaagtctt gtgcttgagc
     5641 agcttgacct gaaacaaact ggcttgcttt gctatctagg cggaattgaa ttggttccaa
     5701 cccagcttct tttcgatctg caaccaacac ttgctccaag cgaggaagga agcttactgc
     5761 tttgttttca tgaaccagca gaacctccat ggcattacaa acagaaggac gactggtttt
     5821 agcattgttg atgatagaca gcgccttgtc ttcgtctgca tccttatcca catagacatg
     5881 gacaatccca gttcctgtct cgataacagg tacaatcgca ttctcaacca ctgcattgat
     5941 caagccagct cctccacgag gaatgagaag gtctagatag cccttggcct tcatcatagc
     6001 ataactactt tcacggctag tatcctccac cagttgaatc acatttggat gaatagtagt
     6061 cgtctccaag cccttcttca aggctgtgac aatggcatgg gttgtttgat aggcatcctt
     6121 accactacga agaacaaccg catttccact cttaagagtc aaagcagccg catcagacgt
     6181 cacatttgga cggctttcat agataatacc gatgacaccc atagctacac gtttttttgt
     6241 gataaccaaa ccattttcaa gctgacttgt ttctaaaact tcaccgattg gatctggtaa
     6301 ggcaaccact tcacgaattc ctcttgccat cgcttctata cgatctgcat ccaaataaag
     6361 acgatccaac atcacatctg agattttccc cttagccgct gccatatcga gggcattagc
     6421 cgctaaaatt tcctcagtag cagccactaa gtgatcagcc atggctagca aggcttggtt
     6481 tttcacttct tcactagctg tgttaatcga ttttttaaca gcctgtacct gttcaaattg
     6541 ttcttgtcta ctcaccatag tttacctcta aaattctgta aaaagtagtt ggatttcagg
     6601 agtaatggaa atccagtcgt cacggtaaat caagacaccc ttggcttttt gaaaacgcaa
     6661 catatcctcc aaagcagatg ctccaaattg cacgcgtcct tttccaagtg attttccact
     6721 ttccttatca aatactgtca cgatatcacc gtaagaaaag actccttctg cttcaacgat
     6781 accagataag agaagactct ttccatgttg agagagagct tccgcagccc ctttatcaac
     6841 ccaaatagaa ccttgactct gagcatagaa ggcaagccat tgtttctggg tacgaagccc
     6901 cttctcttga gcaacaaagt aagaaccatc ctcggtctcc tctgccgcct caaccatgga
     6961 atctgatttc aaggatgagc agatataaac aggaactcct gattccgtcg cgatagttgc
     7021 agccttgatt ttggttaaca tacccccagt tccgtttgac gaaccagctc caccagccat
     7081 atcaataatc tcacgattga tggtctcgat tctctccaag cgtttggctc ttggatctga
     7141 attaggattt ccagtataga gaccgtccac atctgtcaag aaaactaaaa ggtctgcttg
     7201 gaccatcgcc gctacttgag cacttagagt gtcattgtcc ccaaccttga gctcatcaat
     7261 aacgacacta tcattctcat tgatgatagg aattgcccca cggttgagca aaaccgacaa
     7321 agcctgatgg gcatttttat aacgacgctt atccacaaag tcatcttggg tcagcaagat
     7381 ttgtgcagaa acgatttgac gcaagagaag attggtcgta tattcttcca acaaaagtcc
     7441 ctgccctacc gctgctgaag cctgtttatc agcaatttta gtcggacgct ttttaaatcc
     7501 taaggctcca aaaccagccg caatggcacc tgaagacacc aaaatcaact catgaccagc
     7561 ctcgtgcagc atagccaact gctgggtaat atcctttacc ttactacgtg ataaacttcc
     7621 atcctcattt gtcagagaag aagtgcccac cttaaagaca atccgtttgt atttcatagt
     7681 ctcactccga ttattcatat ttatccatta taacatgaat aacaggaaat agaaaagagt
     7741 tgataggaaa aagaaggccc taaaaccttc ttttctacta ctattctgat tccgatttgt
     7801 ttacactcgt ttcagagctt tgtgaagttg aggatgtcaa atcttgacta gttgaagaat
     7861 ttgtaacact ttcatgttga ctcgtttctt tattttcaag atcctttttc actacttctt
     7921 tggattcttt tatttctgaa tgacttgtag ttttaattgt agcagatttc tcgatcggaa
     7981 catccactaa ccaggcacca cttgaatcca cagtatagcc ttctggtgtc ttaccattca
     8041 caagtaattg accattttct ttcaagaagt accatttatc cttgtcttta atccaaccta
     8101 tagctcgtga accacctgtc ttgtagaaat accaatcatt tgccttttta agccagcctt
     8161 gcttcatagc tcctgattct tctagatagt aatgatgtcc agcaacttct atctcacctg
     8221 tcttcatgat accagtagaa tccatatagt accaggcttc tttatctttt acccagcccg
     8281 ttttcatttc ccctgatgga gcaaagtaat accattgccc cttatattga agccaacctg
     8341 tcttcataga gccatcaaca tccaaataat accactgctc tttatcttga acccaaccaa
     8401 tttccatctg attttctttg ttaaaataat accagattcc atcaattttc ttccaatttt
     8461 tagcagaagc accagagtct gtcaaataga accaatgatt gttccatttt ttccattgat
     8521 tctgtaacaa gatacccgtt tggttaaagt aataccattc accttcgatt tcattccaac
     8581 cgacagcata ctctcctgta gaatcaggcg cttgatacca ccagttccca tatgcactct
     8641 tatgccaacc agcttgaaaa cttggaatcg gcttgtagga tgttgaaata ttgacaaaac
     8701 cgtcttttcg aatatcaaaa actgttgcat catagtcttt gctggctgcg ttgattctct
     8761 caattcctcg ttctttgagc caattaacat actcactatc aacaccattt ttccaaggta
     8821 gactatccga agtttgaaca atcaaactcg gactcaaatt tttaatgaaa tccttggtat
     8881 ttgatttgtt ggtatcatgg tgatgattaa acttcatcaa atcaactttt ccaatgagag
     8941 gaccatactt gtcttctgct ccatgaacat tatctaaatc gcccccaagg taaattttct
     9001 tgccattgac tttcaccacg ctaatcaagg aattggaatt gtcatcccaa attttcttta
     9061 attcacccga tgaatcagtt tcattttcat aattatagag ctgaatatcc atgtccccaa
     9121 actgaaaatg agcatcccct tgtgtgatat tttgaataac tgaaacacct ttttctgcag
     9181 cagtctgtaa aaccttatca tagccataca gattatccca tagacgttca gaattagtaa
     9241 tacgactatc actatatttc ttaagataga ctcggtcaac tggataggta gacagtaatt
     9301 catcaacatt tccaatatga tcactgtggg tatgggtcac caaaataaaa tcaagttttt
     9361 ggacacccaa ttccttcaaa cgacgaaaga cacggtctgt tagaacatgc ttataagacg
     9421 tttcaattcc ttctctccat ggataacgag aatcacttcc atctgggaaa tcataatctt
     9481 ctcctgtatc caccatggca aaatgtccat tgctttcaag aataatcgca tcactgccac
     9541 cttcttgaac attgataaag tggattttat ttcctgaact ttcttgagcc tgaacattcc
     9601 cataccatga caaacctaaa aaagcgccta caagtgctaa actagttaat ttctttttca
     9661 ttcttacttt ctcaatctct ccaaggtttc cttaaaaatc tctgggatat ctgctttaaa
     9721 ttccaaggtc ttacctgttc tcggatgagt aaaacctaaa gtcttggcat gaagaaattg
     9781 tccatgtcct ttcaaagtct tgcgaggacc atagacctca tcaccagcga ctggatggcc
     9841 gatataagcc atgtggacac ggatttgatg agtgcgccct gtctccagtt gcaactctac
     9901 taagctataa tcgccaaagc gttccaagac gtgaaaacgc gtcactgcag gcttcccttt
     9961 agcagttaca gcctgtttct tacggtcttt ttcactccgg ccaatcggcg cttcaattac
    10021 accacgatca ttaggcagat ttccatgaac aatcgcccaa tatttgcgga gagacttttt
    10081 atctttgagt tcttgggcaa gtactagatg cgcatcatcg tttttagcaa tcatgagaag
    10141 acctgacgta tccttatcaa tacggtgaac aatccctgga cgcagaaccc cattgatacc
    10201 cgacaagtcc ttaatatgat acatgagggc atttactagg gttccactgg tatgaccagc
    10261 actcgggtgc acaaccattc cctgaggttt gttaacgaca gccacatcct catcttggta
    10321 gactatttct agcggaagat cctcagccac atactctaat acctctggtt ctggcacatg
    10381 gtaagtgacg acatcaccct cttggactgt gtatttagct ttcttgactt gaccattgac
    10441 caagacctgg cctgatttaa tttgttcatt cgcgagacta cgtgataatt ctgacaaatc
    10501 tgacaaagcc ttatccaaac gcagaccacc agtttcaatt ttaatttcca tttatttcct
    10561 cttttagcat tgcaatcaat aaaataatca ctccaaccgt cagatagcta tctgccacat
    10621 tgaaaattgc aaagttgata aagtcaaggt ggaacatatc cacaacaaag ccctgactga
    10681 ccctgtcaat aaagtttcca agaccacccg cgattattag agtcaaaccc aagaacatcc
    10741 agaatgagtc ctccatgtgt ttatgtaaat accaaatggc acctatcacg acaaccagag
    10801 taatgacagc gaataacagc tgctgatctt gtaagataga aaaggctgca cctcgatttt
    10861 gcaggtaggt caagctaacg aaattgggaa tccaggagcg cacttcaccc agtggaatct
    10921 gctggacgat ataggatttg accaactgat ccagcccaat taaaagcagt acaatgactg
    10981 ccactattgc tctttttttc atgatttcct cttttgatca aaatattctt gcatgacttc
    11041 tacgaagaga gtcccagctt gactaagctc cacttcttca cgtttaacat agaccatgcg
    11101 gttatctagg ttatccttga gacgaataac tgtaatgcca ttaacactgt cactatctaa
    11161 aaatccagaa cctgtcgcat aggcgtccgt ccgctccaaa ataccattca aggtggcacg
    11221 gtctgtcaca ttaaacatct gtgagctagc gctggtatcg acaaagttct ctgaataata
    11281 aaggtactcg tctttctctt gagtgaaacg aaccgttggt aaatccgcta aatcctccat
    11341 gactaattcc tctttctggg ctaaaggatg accctcacag agataaatat gggtatggaa
    11401 aggaatcaat tcgatgacct ccagacctaa cttttcaacc cgttgcataa tccccttttt
    11461 attttgattg ttgaggtaga taatcccaat ctcactatgc ccttgcgcca cttcatctaa
    11521 tatttgaaca gtagttgatt caaaaatacg gaagttctta tagtcaggat agcgctctga
    11581 aaaggccgta atagttggtg gtaagaagtc atagtgctgg ctagcaacgg aaaattcatc
    11641 tttttcttct tcaggattgg catactgatt ttgaaaaata tcaaatcctt taaccaattc
    11701 ttgcgctttt tcataaaatt ccatcccacg acgggtcaag aaagtccctg agctggtccg
    11761 acggaaaatc ttaaagccca actctttttc caaatcacga acagaaatag acagactcgg
    11821 ctgactaaca tacatctttt cagcagcttc acgaaaagta ccactattgg caatagccac
    11881 aacatagcgt aattgttgaa tgttcatctt ctacccccaa cttctttatc ttttcattat
    11941 accatatttt agaagttttc caaaaaggaa aaaagaacat cctattcttc ttaactatct
    12001 tcactatctg cctttctcac gccaatctta ttttcaaaat caattcaaaa aaataagtgg
    12061 ctacacacca cttcagtatc ggaaagaaaa acgttgacta tttgtgaaaa aagaaaatgc
    12121 cggaaaattc cgacattttt ttagtaagct aacttcctga aaataggagt aaccaaacat
    12181 cccagaaggc agtgatattg atgagaatat gaactagtat tggatagtag agatttttag
    12241 tcatgcgata caatagagct aaaatcagac ctccactagc ataaatgaaa aaagcaagag
    12301 gagttaaagc aaaattgata tgaatataac cgaaaataat agcagaaagc aaaacatctc
    12361 cgtaccaagg tgagtttttg aaaaaggttg tcataagcac acctcgataa atcaattcct
    12421 cagcaatagg ggcgatgaag caaacgatga gcaagaaata agggaactcc tgtctcccca
    12481 tcatttctac cgtttcattc aaagaaatct gatttgaaga cagggatatg aaatacgaaa
    12541 agaggaagtc agacatatat gaaatgatgt agcccagtaa aaggtagatg aagtacctca
    12601 gctgccactt gaaatgaaaa attttctttc ctgcaaaaac cagtagatag atgaccgcta
    12661 agaaaagaac tccgctctcc atcaaaagca gaatctgaaa aaattcacga cttgctggta
    12721 gatagggctt tgcgaggtga ttgaaaactc tccaaaacca agttgatttg taaaaaatta
    12781 aggacaatgc tagtaaaatt tgaatagccc gttttttcat attaaattct ctgctttctc
    12841 cacttatttc ttcatattac taataaattt tacttaaaat ctcgcagcac ttcctttgca
    12901 aagatgattg cctcctccaa tatatcctaa atcataggtg cctctgggac aaaatccatg
    12961 aaccggcaga gttaatactg gttctatttc ccaatcgtac ctaccattag gatttttacc
    13021 atatgaatct gctccacctt gtatcagctc taattcttca tttgttagat ttatattttt
    13081 tgtcattaaa atcatgatat atttcctcca ttattcttca gattagttga gtaatctgat
    13141 actcatacct acttacaaaa aaactattat attaagttgg ttttttaatt tgtctagttg
    13201 caacattgac aaacatagta tagcatatct ttgcgaaata tcctcttcaa atcatgaatt
    13261 gtcatcaaaa catcttaaac tataaaatca attagtctca agctttctat caatttcttc
    13321 tccaaaatat gctataataa tagcaaaaga taaagaagga agacctatga ttaaactact
    13381 agccttggat atggacggca ccctcctcaa tgaagccaag gaaatcccac aagctcacat
    13441 tactgctatt cacaaagcca ttgaaaaagg tgtcaaactg gttctctgta cgggtcgccc
    13501 ccttttcggt gtcctcccct actacaaaaa actgggactc gacctccaga atgagtatgt
    13561 gattgttaac aacggttgtt caactcacca gactagcgac tggggcttgg ttgactggca
    13621 agaacttagt ccagctgaca tcgaatacct ctatgacctt gctgaaaaga gtgatgttca
    13681 gttgacactt tttgacgagt cacattattt tgttctcggt ggaaagccca atcaagttat
    13741 tgaaaatgat gctaaactag tattttcaga cctgactgaa atttctcttg aggaagcgac
    13801 tagtggaaag ttccggatgt tccaaggtat gtttttagga acaaaagaac aaacagacga
    13861 ttttgagcag cgttttgctg aagagctttg ccaacgattc agtggagttc gttcgcagcc
    13921 tgtcatttat gaagcaatgc cacttggaac gacaaaggct actgctcttt cacgactagc
    13981 tgagattttg aagattgatt cctcagagat tatggccatg ggcgatgcta ataacgatat
    14041 cgaaatgctc cagtttgcag ggcttgggat tgcaatggga aatgccagcg attatgtcaa
    14101 atctcttgcg gatgccgtta cctcaagcaa cgaagaagac ggcgttgcgc gtgctattga
    14161 gaaatatatt ctataaaaaa gaaaagcaaa tagacagaag ttactgctat ttgctttttt
    14221 gctaatattt taaaatacgg actaatcaat agagaagaat agcgaatcat aaaaatcgat
    14281 ttactagatg ccatagtatc ttatagttgc taataagaag ttagtctagc agaatgaatc
    14341 tctcatttct cccacactaa tctgtaattt gtctatacat ttctggtctt ctatctcgaa
    14401 acaagcccca gtttaggcgt tcacttgctc ccttgtctag gttataagta gctaacagaa
    14461 cagcttcttc ttgtctttca gctcgttcta gaatagctcc tgtttcatcc gtcataaagg
    14521 aggaaccgta gaagtcaaga ctggaactct gtccgccatt ttcctcacta ggagtaacct
    14581 cctctaaacc ataacgattg gctgcgatga ctggaacaat attcgctgct gcgtgccctt
    14641 gcatagtacg ttgccagtga ccacaactat ctgtatccaa aattggctct gaaccgatag
    14701 ctgtaggata aaagagcaat tcagcaccat tcaatgcaag acagcgcgct gtttcaggga
    14761 accattgatc ccaacagata ccgataccaa tcttagcata gcgagtattc cagaccttga
    14821 aaccagtgtt accaggcgtg aaatagaatt tttcttgata ataatggtca tctggtatat
    14881 gggtctttcg ataaacgccc agcacttccc catctgcatc aatgacggca atagagttat
    14941 acaagacatt accatctttt tcatagaaac tgattggtaa aacaacttgt agttccttag
    15001 caagcaactt aaaatgctga atggcagtat tttccgctac agattgggca tactggtagt
    15061 agtcatactg acgttcctga cagaaatagg gatgttcaaa caactcgggc aagagaataa
    15121 tttgggctcc ttgctcagca gcctgacgta ctaaacgctc tgcggtttgg atatttgttg
    15181 ccacatcctt agcgcattgc atctgaatgg ttgcaactct tacatttctc atctttttct
    15241 cctattctgg aatttgttgg gtgatacagt ggatattgcc accacctaag agaatatctc
    15301 tggctggtat tccgacaact ttacggtctg ggaaacactt gctgaggata tctaaggcca
    15361 cttggtcgtt tacatcctca aactgtggaa ccaagacagc cttgttggcg atataaaagt
    15421 ttacgtagga agctgctagt cgttcacctg cgtatcgctc ttcttctcct tcttcataga
    15481 tgtagcctgg caaatcttct tctgtcacaa cttgtcgaac tgcagggata ggcaatttat
    15541 gaatggtgaa gtgacaacct tttgcatctg tttcctgttc taagagttcg agatctgctt
    15601 ttgacatggc atactgggga tcattttcgt catctgtcca agccaaaaca acctcagcag
    15661 gaccaacaaa ggcaacaaca ttatcgacgt gttcattggt ttcatcctga taaataccat
    15721 aaggaagcca aataactttt tcagcaccaa gactttctaa taatgtgttt tcaatctcct
    15781 ctttagtcaa gttaggattg cgaccaggac taagcaagca actttcagtt acgagaatag
    15841 ttccttgacc atcgctatgg attgcgcctc cttccagtac aaaaggttta gcatcataga
    15901 caggcctttc caaggcctca gcaaaacgac tggctacttg gtcatcctct tcataatctt
    15961 gataaagacc atcataggtg cctccccaag cattaaaggc ccaatccacg gctaatttct
    16021 tacctttatc attgacgaga atggttgggc cagtatcacg cgcccaggca tcattggtgg
    16081 gaatgtctaa ataaacaacc ttgtctccaa gataggattg ggcttcagat agataggcct
    16141 gctccaccaa aagatagact ctttcccctt ctgctatggt ctcgatgatc tgagtaaatg
    16201 ctcttttagc agcctttcct tgaaaaggcc atgatcctgg tcgagtcggc catatcatga
    16261 gggtaccatg atggggttcg tactctgctg gcatgtgata gcctaatttt tttggactgt
    16321 ccatcatgat aatctccctt taaagtcttg atagccaaaa gctttgagta agctacagtc
    16381 tccctgttcg tccatgagat agagacttgg caatccaata ccattaaagg tattattttt
    16441 gacaaaagaa taaatggcca tgtcttgaaa ataaagtctg tctccgattt ggactggatt
    16501 ttcaaaacta taatcaccaa tcacatcgcc agtcagacag gtattagaag aaagtctgta
    16561 ggtatgggct ttttcctgtg actcaaagcc atttctcaaa ggtggacgat agggcatctc
    16621 aagtacatca ggcatatggc aggtcgcaga ggcgtctaaa accaagattt ccataccgtt
    16681 ttctacaata tctaatacct cagttgctaa ataacccgca ttaagcgcaa tggcttcacc
    16741 aggctcgata tagatttcaa gattgtaagt ttttcggata cgcttgattt ctgaaatcag
    16801 caaatccaca tcgtaacctt ctcttgtaat atgatgacca ccacccatat tgagccattt
    16861 tacctcatgt aagtagggac caaactgttc ttctactgct ttcaaagttg tttgtaaatc
    16921 atctgctccc tgctcgcaaa gggtatgaaa atgaagtccg tcaaccaaat ctagcaaatc
    16981 gctcggaatc ttgtctatag taactccaaa gcgagaacca ggtgcacaag ggtcatagag
    17041 cgcgtgatct ccttgagttg aacactgagg gttgaggcgc aaaccaacac tgacaccagc
    17101 ctctcgacaa cgagccccat gcttacgcaa ctgtctctct gagttaaaga cgatatggtc
    17161 tgttatccca agcaattcct ccatgtcctc atccttgaaa gctggtgcaa aaacatggac
    17221 ttcaccagga aattcttccc ttgccaattt ggcctcatag agtccactag ctgtcgtacc
    17281 tgatagatac tggctaatca agggataagt tttgtagagg gaatatgcct tctgggcaag
    17341 caagaccttg caaccggcct cttcttgtac atattgtaga atgcggcaat tagcttctaa
    17401 cttggccaag tcaataacat aggctggtgt tggtacttgt tctaacttca ttagtccaac
    17461 atttgtggat tttcaaccac aacccatggc aaaccatact cattcaaagc ttccatgaat
    17521 ggatctggat ctaactcctc aaggttatac actccagctt gtttccaagt tccgttcatg
    17581 actaattttg tcccaatcat ggctggaacg cctgtcgtgt atgaaattgc ttgtgacccg
    17641 acttctgcat agcactcttg atggtcgcaa acattgtaga tgtagatagt cttttcaacg
    17701 ccatctttga cacctgtaaa gatacatcca atattggttt tacctacagt acgtggacca
    17761 aggctagcag gatctggaag caaggctttc aaaaattgaa ttggaacaat ttcttggccg
    17821 ttaaagttaa tggtatccgt acgaaggagt ccaacatttt caagacattt catgtgcgtc
    17881 aagtaagatt gaccaaaagt cataaagaaa cgaatgcgtt tgacacctgg aatgttcttg
    17941 gccaatgatt cgatttcttc atggtgaagg agatacatat ctttttgtcc aacttgaggg
    18001 aaatcatact cacgcttgat agacatagct tcgacttcga cccatttccc atcttcccag
    18061 taagaacctg gcgcagaaac ctcacggaga ttaatttctg gattaaagtt ggttgcaaat
    18121 ggataaccgt ggtcaccgcc attacagtct aaaatgtcga tataatggat ttcatcaaaa
    18181 tagtgtttga gggcataagc tgaaaagaca ctagttacac ctgggtcaaa accagaacca
    18241 agaagagcag tcaagcctgc ttctttgaat ttctcttgat aagcccactg ccatgagtag
    18301 tcaaagtagg ctgtaaaacc aagttcctta caacgttttt cgtagatagc acgccactca
    18361 gggtcttctg tgtcttctgc ttcgtagttg gctgtatcga tatagtgaac acctgttgcc
    18421 aaacaagcat ccataatggt taaatcttga taaggcagag ctacattcaa aacagcttct
    18481 ggtttgtagc tttcaatcag agcaatcact tcttcaacct tgtcagcatc aagagcagct
    18541 gtctcaatct ttgtacttgt tttgccttcc agtttagctt tcaagtcatc gcattttgac
    18601 ttggtacggc tagcaatcat aatctctgta aatgtttcgc tatcttgaca aatctttgaa
    18661 atagcaactt gggcaacgcc cccacaacca ataactagta aacgactcat ttttttcctt
    18721 cctcttcttc taaaatgtcc tcaacatact tgggcaacat aaaggctccc acgtgtaagt
    18781 ttgcagtgta gtattctgtg aaaagctggc gttttttcca gccttccttg tcaaaatctt
    18841 tgacagggtg gtattttttc gatgcaaatc caaacaacca atagccagct gggctagttg
    18901 gaatatgggc ctgataaacc cgactgattg gaaaggcttg attgaccttg cggtgcatgc
    18961 ttcggcaggc cgactcatcc tcgtcaaaga acggactccc atgctggtaa atcatgatgc
    19021 cgtcttcctt cagagctcga taactattgc cgtagaattc cttggtaaag agtccttccg
    19081 tatggccaaa tggatctgtc gcatcgttga tgataatatc atagtcatat tcgcagtttc
    19141 gcaaaaagcg tagcccattt tggtagtaaa tggtaacacg aggatcatct aggcctgcag
    19201 caaagtctgg gaaatactca cgacagacct cgaccaacat ctcatccggt tccacgatat
    19261 cgatttgttc cagttcagga tagagtgtta atacttgggc aacaccgccg tcaccacccc
    19321 caataaccaa tactttcttt ggatttgggt ggacagccat gggaacgtga acggtcattt
    19381 cattgtagac gaaatcatcc gcatctgaga acaagacatg gccatttaaa atcagtattt
    19441 tcccaaaagc tggcgtatcc aagacttcga tatcctgcca ttcacttttt ccagcgtaaa
    19501 gttgcttggc tgttctcaga gacaatttga catctggagt atgaacttca gaaaaccata
    19561 aatccatcta tttctcctta tattatattt agcgcagtta gctactgcca aagcccaagt
    19621 ggtatacttg gaataagcca ctgtggatta gttcatttcc tccaatcgct tgacgatttc
    19681 cgaaagggtc taaccacagc tttttgtttc aattggtaat gagtttgata acgcatagac
    19741 gttttatctc gtctaaggta acaaggcaaa aagttcgtgg ataaccaagt agacttgaaa
    19801 tactatatct ggaggtactc ccatgcttta tgtgggcatt gatgtcgcta aaaataaaca
    19861 cgatgttaca gccttgaatg ttcgaggaaa actgttctta aaccactcac tttttcaaat
    19921 aataaagctg gttttgaact cttagatctg tctcttcgac aactcaacca agactgtctc
    19981 atcgctcttg aaaataccgg acattatgcc tttaatctac tgaacttcct gcatgaacaa
    20041 ggatataaag tttacaccta cactcctttg ctcatcaagg aatttgccaa atcattatca
    20101 cttcgc
//
LOCUS       DAVBEO010000043        19766 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 009
            SAMEA1678075-rid20185393.denovo.043, whole genome shotgun sequence.
ACCESSION   DAVBEO010000043 DAVBEO010000000
VERSION     DAVBEO010000043.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678075
            Sequence Read Archive: ERR226392
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 19766)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19766)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980207.1
            Genome Coverage       :: 150x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:50:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 72 of 147
            Pseudo Genes (incomplete)         :: 72 of 147
            Pseudo Genes (internal stop)      :: 42 of 147
            Pseudo Genes (multiple problems)  :: 32 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19766
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678075-rid20185393.denovo.043"
                     /strain="KS 009"
                     /db_xref="taxon:1313"
     gene            complement(481..1206)
                     /locus_tag="VQ543_001559"
     CDS             complement(481..1206)
                     /locus_tag="VQ543_001559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000771194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2612261.1"
                     /translation="MKLLKNELIKSKIFLFIIVDICIQILVILAIKTYILDISAPYSE
                     LDYNKYWYVLHALIYMPMIFPIQILYQNLREALIEDNNNGWNIMVINTNNLVKIIYIK
                     VTINIVRCFICYFVYTIFSLIQLGGMGTDMLLTNIIFPNIIFPNIMSFLLFLPIAIFM
                     QICCIRFDSILAKALPNILLILIVLITFQSDWNIFIPATYYYTEIQSTTNLGIKLLVC
                     IWIMGFEFSLLPKLIKLKEQNLV"
     gene            complement(1219..1956)
                     /locus_tag="VQ543_001560"
     CDS             complement(1219..1956)
                     /locus_tag="VQ543_001560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET2612262.1"
                     /translation="MIKLEFLKQKKSILWFVLIFPIILNALLYIDLTFRYRGYLLVHQ
                     NELALSNWQLIFKEQTIFYFSELFYLVLSLIIYEVFAVEFKNDAWLTVISLPFRNKYT
                     INSKLLITVVYTFTFWLSDYISLYVIGKAIDNSLEIGLIFFLKTFTIQLISSLMIMLL
                     YFLTLVLIRKISGIIPIGIIMMILTISIYYNDYNFKIYLPFTYLSHAFRVTESQFYMI
                     LLSNIIIIVLFYILIRKLNERSFEMKL"
     gene            complement(1949..2677)
                     /locus_tag="VQ543_001561"
     CDS             complement(1949..2677)
                     /locus_tag="VQ543_001561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HET2612263.1"
                     /translation="MAIVEIINLTKSFKDIEVIHNTSFYLNKGKVYGFVGPNGAGKTT
                     IIKMILGILKPDSGKITIFNQTVEQNSKNILSRIGLVLGPSFYGHLDAYKNLKLIANM
                     KGLSLDTERLNEYLSMVGLKDVKKKKVKNFSMGMKQRLSIAASLLGSPEILIWDEPIN
                     GLDPQGVIEIRSLIRFLQEKKGITFLISSHILSELDKVISDIIIINYGKVEFFGSCHY
                     LLQKYNCRNLEEAYLACLAGGEYD"
     gene            complement(2711..2881)
                     /locus_tag="VQ543_001562"
     CDS             complement(2711..2881)
                     /locus_tag="VQ543_001562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2612264.1"
                     /translation="MKKVNEYVISTAASLGVMIGIVFAIFLDFPVEYGISLGLLNGIV
                     LGSLIVYKNNKN"
     gene            complement(2924..5017)
                     /locus_tag="VQ543_001563"
                     /pseudo
     CDS             complement(2924..5017)
                     /locus_tag="VQ543_001563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397758.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase domain-containing ABC transporter"
     gene            complement(5010..5558)
                     /locus_tag="VQ543_001564"
                     /pseudo
     CDS             complement(5010..5558)
                     /locus_tag="VQ543_001564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000059560.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(5639..5701)
                     /locus_tag="VQ543_001565"
     CDS             complement(5639..5701)
                     /locus_tag="VQ543_001565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_128650800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SHP2/SHP3 family peptide pheromone"
                     /protein_id="HET2612265.1"
                     /translation="MKKISKFLPILVLVMDIIII"
     gene            complement(5870..6858)
                     /locus_tag="VQ543_001566"
                     /pseudo
     CDS             complement(5870..6858)
                     /locus_tag="VQ543_001566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003050775.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus and C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
     gene            complement(6807..7934)
                     /locus_tag="VQ543_001567"
                     /pseudo
     CDS             complement(6807..7934)
                     /locus_tag="VQ543_001567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000423473.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="alpha amylase N-terminal ig-like
                     domain-containing protein"
     gene            complement(8097..8981)
                     /locus_tag="VQ543_001568"
     CDS             complement(8097..8981)
                     /locus_tag="VQ543_001568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000710121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
                     /protein_id="HET2612266.1"
                     /translation="MKKAMVIINPTSGGEKALDYKEKLENKAKEYFEYVETKITEKAL
                     DATHFAEEASREQYDAVVVFGGDGTVNEVISGIDERDYIPKLGIIPGGTGNLITKLLE
                     INQDIDGAIDELDFDLTNKIDIGKANDNYFGYIFSIGSLPEAIHNVEIEDKTKFGILT
                     YAVNTMKSVMTDQVFNIKVETENGNYVGEASHVLVLLTNYFADKKIFEENKDGYANIL
                     ILKDASIFSKLSVIPDLLKGDVVANDNIEYIKARNIKISSDSELESDVDGDKSDNLPV
                     EIKVLAQRVEVFSKPKED"
     gene            complement(9093..9947)
                     /locus_tag="VQ543_001569"
     CDS             complement(9093..9947)
                     /locus_tag="VQ543_001569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000900021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ADP-ribosylglycohydrolase family protein"
                     /protein_id="HET2612267.1"
                     /translation="MLGAIIGDIVGSVYEWNNIKTKDFPLFRKDCFFTDDTVMTCAVA
                     EAIMNGGQKDDFIDAMKKYGRMYPNADYGARFNAWLNSDNREPYNSFGNGSAMRISPC
                     AWIMDCGFYAKTGIWPSSRGLTSLSAEVTHNHPEGVKGAMATADAIFLCRFYFGGYCR
                     EYEQSINDNLTECKRRIKDYIEKEYDYNLSQTLDEIRPNYRFNETCQETVPQAIIAFL
                     ESRDFEDAIRNAISLGGDSDTLAAITCNIAEAAYGIPDWIKDKAYSYLDEPLKDVVRR
                     WENRIKAY"
     gene            complement(10005..10763)
                     /locus_tag="VQ543_001570"
     CDS             complement(10005..10763)
                     /locus_tag="VQ543_001570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000262024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="HET2612268.1"
                     /translation="MVVYIRQSKLPSEVSINKYNAQVGAYLQGEEVILYQSFSEIKEL
                     TSEDIVVDYIMETRALLKMMGLNVPVYDYPIELKEFYGRKIYAGILGEIVNIPDNWGK
                     FIKPKAGSKVFTGRVVNGTHDLIGIGLPFDYPIWISEVVEFIAEWRCFVLDGRVLDVR
                     PYTGDYHAQFDASVIDEAISCWKDAPIAYGLDIGVTRDGRTLVVEVNDGYALGNYALS
                     PLKSINFHRARWKEMVKPYFEKNEIFKIQQDVVF"
     gene            complement(10825..11013)
                     /locus_tag="VQ543_001571"
     CDS             complement(10825..11013)
                     /locus_tag="VQ543_001571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopG family transcriptional regulator"
                     /protein_id="HET2612269.1"
                     /translation="MATDKNRIMISLDDKNLEKLENLVEDARDRRGMRLTKSQVIELL
                     LNTVDYFDDIMGAIYSKK"
     gene            complement(11335..11901)
                     /locus_tag="VQ543_001572"
     CDS             complement(11335..11901)
                     /locus_tag="VQ543_001572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2612270.1"
                     /translation="MVILELYQNDYSKDLVAFDSIEDGKAFVAQIPGYTLETEDGFEV
                     EYFNPKNIPDYMEIIFNGNIVPLSKFMFDPEENVNIIWKEISNLSLKNDRVIEGYSKI
                     DAYVVNNHEVKTYVETRETNYRKAKDFLESRGYEIDRSFFGSEDGEAILYRKKGIEVW
                     HFLCHLDPMFVEIEDVEGYVKEEVGEIQ"
     gene            complement(12169..13848)
                     /locus_tag="VQ543_001573"
     CDS             complement(12169..13848)
                     /locus_tag="VQ543_001573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000031864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HET2612271.1"
                     /translation="MSKEKIKVYLYTRVSTSIQIEGYSLEAQKSRMKAFAIYNDYEIV
                     GEYEDAGKSGKSIEGRIQFNRMMEDIKSGKDGVSFVLVFKLSRFARNAADVLSTLQIM
                     QDYGVNLICVEDGIDSSKDAGKLMISVLSAVAEIERENIRIQTMEGRIQKAREGKWNG
                     GFAPYGYKLEDGKLFINEEEAVAIRTIFDQYVNTTIGANGISKYLENHGIRKIPRQNG
                     KNPLFDAGLIRKILKNPVYNGKIAFGRRTLEKVHGTRNEYKQVEQDEYLISEGIHEAI
                     VSDEVWQAAQVKLKSQAKKYEHVNKGKDTRTHLLSGIVKCPICGVGMFGNKCIKKKKD
                     GTKYKDFYYYGCNHRQMIRGHKCTFSKQIREELLDDAVAEVIVKIVSNPKFASMMQEK
                     INMKVDTSEIEKEIDNYQKELRKSHSTKFKLIEEIDNLDVEDKHYKRRKQDLDDRLYR
                     MYDKVDELESSLIDAKAKKQTIEAEKLTGDNIYKVLIYFDKLYKVMNDVERRQLISAL
                     ISEIQVYEEKQSNGQWLKSITFKLPIIEENLNIGLDNDEQVECVSLLEKRS"
     gene            complement(13940..14101)
                     /locus_tag="VQ543_001574"
     CDS             complement(13940..14101)
                     /locus_tag="VQ543_001574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005761276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2612272.1"
                     /translation="MDNDWNGLADLIANLIAKYAGALDLDNLPDPTPAKNQEMKNSFD
                     MAKTQIETD"
     gene            complement(14785..15099)
                     /locus_tag="VQ543_001575"
     CDS             complement(14785..15099)
                     /locus_tag="VQ543_001575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001835032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2612273.1"
                     /translation="MGITWKDIEIDKEREGEIDKKSTPIFYGEFKNVRLSKEEYKNLK
                     EKLNSHTDIMINKLSRYMESSGKTYQNHYVTILKWYEEDKDKLRQKGLNKKMNYDVGE
                     SL"
     gene            complement(15065..15454)
                     /locus_tag="VQ543_001576"
     CDS             complement(15065..15454)
                     /locus_tag="VQ543_001576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000690676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HET2612274.1"
                     /translation="MPKRYLLDGKTPRISATNIDNGILGYYEDIDDKNYRVFENFISV
                     SFLGAVFYHKYKASLDMKIHCLKLKNKELNKEVAFYLTSIIRQALKNTEYKDQISSTV
                     LPDIKIKLPIDSRGTPDWNYMERYRDR"
     gene            complement(15842..16636)
                     /locus_tag="VQ543_001577"
     CDS             complement(15842..16636)
                     /locus_tag="VQ543_001577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000677523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2612275.1"
                     /translation="MKGLWSNNLTCGYDEKIILENINIKIPEEKISVIIGSNGCGKST
                     LIKTLSRLIKPLEGEVLLDNKSINSYKEKDLAKHIAILPQSPIIPESITVADLVSRGR
                     FPYRKPFKSLGKDDLEIINRSMVKANVEDLANNLVEELSGGQRQRVWIALALAQDTSI
                     LLLDEPTTYLDISYQIELLDLLTDLNQKYKTTICMILHDINLTARYADYLFAIKEGKL
                     VAEGKPEDILNDKLVKDIFNLEAKIIRDPISNSPLMIPIGKHHVSS"
     gene            complement(16636..17643)
                     /locus_tag="VQ543_001578"
     CDS             complement(16636..17643)
                     /locus_tag="VQ543_001578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HET2612276.1"
                     /translation="MQNLIIGIQKRKNRITLFSSLFLLIIISLSFFILLIGDESYSFS
                     TLIKVLNSETVPGASFSIMEIRLPKLLAGIIAGWSFGLAGFIFQTMLRNPLASPDIIG
                     VTSSSSIAAVFCILVLKTNSLTTGIISITCGLTSSLILFLLAKKDGFSAARLIILGIG
                     FQAVTRAGTSFLLLKVARYELQEVMRWLSGSLSFTKLDDIPLVLIVSIIATILVLFFN
                     KRLEIIELGEEIAIGLGANPELSRLVLIFCAVSLTAFSTSITGPIACISFLAGPIALN
                     IGKKRSPILAGLVGILLVLLSDIFSQNILPARYPVGVVTGLLGSPYLIYLLIKMNRRN
                     I"
     gene            complement(17643..18650)
                     /locus_tag="VQ543_001579"
     CDS             complement(17643..18650)
                     /locus_tag="VQ543_001579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001244688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HET2612277.1"
                     /translation="MRNKKQINLGIIFVICLGLLITIFLSLKLGTKEINIRDFLATFG
                     MGNTNDDFIKSIIYKRIPRTIFAILAGSSLAISGVLMQSVTRNPIADPGILGINTGAS
                     LSVVIGLSFLGISSSISHISFAIIGGLVSAIFVYAIAVSGKAGLTPIKLALSGTCVSM
                     ALSSFVSFLILPNNNVLDKFRFWQIGSLGAATLSSISTLLPFIILGHLIAIFISSDLN
                     ALAMGDEMAVGLGVNVNRIRSLAIIASVLLCSSITAIGGPIGFVGLIVPHFCGLFISK
                     DIRTMTISSSFIGAELLLICDIIGRMLGKPGEIEVGIITAIIGGPVLIYVTMKNRGVN
                     N"
     gene            complement(18640..19665)
                     /locus_tag="VQ543_001580"
     CDS             complement(18640..19665)
                     /locus_tag="VQ543_001580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000790748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-siderophore ABC transporter
                     substrate-binding protein"
                     /protein_id="HET2612278.1"
                     /translation="MKNKFFLIAILAMCIVFSACSSNSVKNEENTSKEHAPDKIVLDH
                     AFGQTILDKKPERVATIAWGNHDVALALGIVPVGFSKANYGVSADKGVLPWTEEKIKE
                     LNGKANLFDDLDGLNFEAISNSKPDVILAGYSGITKEDYDTLSKIAPVAAYKSKPWQT
                     LWRDMIKIDSKALGMEKEGDELIKNTEARISKELEKHPEIKGKIKGKKVLFTMINAAD
                     TSKFWIYTSKDPRANYLTDLGLVFPESLKEFESEDSFAKEISAEEANKINDADVIITY
                     GDDKTLEALQKDPLLGKINAIKNGAVAVIPDNTPLAASCTPTPLSINYTIEEYLNLLG
                     NACKNAK"
BASE COUNT         6376 a         3631 c         2619 g         7140 t
ORIGIN      
        1 tggacatttt gaactaaaat taatttatta aacatatctc ataagcatat ctattatagg
       61 tgagacaata ttaagaaaga cggttaaaaa acaacctgac tccactggaa ttcaggaatc
      121 aggtcgctta agattttata ttattttact gtctacttga cagggagctg ttcaccaatg
      181 ggaatctata gctttttttg tgactgagaa ctattttatc tcagacttct tcaacacacc
      241 ttattattgg gcacttacgg aaggttaatg aattatttaa aataaaagta aagagaagca
      301 aacagacact ctatagctgt tagacgcttt ttagagtaat aacaatttga taaagtgaat
      361 acaacttgct taattaagcg taagaaacca gaatcataaa atcaattact ttgaagtcat
      421 gactcacgtt gtattgtttc attgttaatc gtattcaatt atttaatttt cgagcaacat
      481 ttaaactaga ttttgttctt tcaattttat tagttttgga agaagggaaa attcaaatcc
      541 cataatccag atacaaacta ataatttaat acctaagttt gtagttgact gaatttctgt
      601 ataataataa gttgcaggta taaatatatt ccaatcactc tgaaacgtga ttaaaacaat
      661 aagtatcagc aaaatattag gtaaggcctt tgctaaaatg gaatcaaatc ttatacagca
      721 aatttgcata aagatagcta taggtaaaaa taacagaaat gacattatat tgggaaatat
      781 tatattggga aatattatat tggttaataa catatcagtt cccataccac ctaattgaat
      841 taaagaaaaa attgtataaa caaaataaca aataaaacat ctcacgatat ttatcgttac
      901 ttttatatag atgattttca cgagattatt agtgttaatc accatgatat tccaaccatt
      961 attattatct tcaatcaatg cctctcttag attttgatac aaaatttgta taggaaaaat
     1021 cattggcata tatattaaag cgtgtaaaac ataccaatac ttattataat caagctctga
     1081 gtatggtgcc gaaatatcta aaatatatgt ttttatagct agaatgacta gaatctgaat
     1141 acagatgtca acaataataa ataaaaatat tttactctta atcaattcat ttttaagtaa
     1201 cttcattttt attacctatt aaagtttcat ctcaaaactt ctttcgttca atttacgaat
     1261 taatatataa aaaagtacga tgattattat attagatagt aaaatcatat aaaattgact
     1321 ttcagtcact ctaaaagcat gagaaagata agtaaatggt aagtaaatct taaaattata
     1381 atcgttgtag tatatgctaa ttgttaaaat catcattata ataccaattg gtattattcc
     1441 agaaattttc cttataagta ctaaagttag aaaatataat aacattatca tcaacgagga
     1501 aattaattga atggtaaatg tttttaaaaa gaaaatcaaa ccaatctcta aactgttatc
     1561 aatagccttc ccaataacgt ataagctaat ataatcagac aaccaaaaag taaatgtgta
     1621 aaccactgta atgagtaatt tagaatttat tgtgtacttg tttctaaatg gcaatgaaat
     1681 tacggttaac catgcatcat ttttaaattc tactgcaaac acttcgtaaa ttattaaaga
     1741 tagaactaaa taaaatagtt cagaaaaata aaatattgtt tgttctttaa aaattaactg
     1801 ccaattagat aaagcaagtt cattttgatg caccaataaa taacctcgat acctaaaagt
     1861 taagtctata tataacaaag cattcagaat tattggaaaa ataagaacaa accataagat
     1921 gctttttttc tgctttagaa actctaattt aatcatattc acctccagct aaacaagcta
     1981 agtaggcttc ttccagattt cgacaattat acttttgtaa aaggtagtgg caagaaccaa
     2041 aaaattcaac tttcccataa tttataatta taatatcaga tatcacttta tccagttcac
     2101 taagaatatg acttgatatt aaaaatgtaa tacctttttt ctcctgtaga aaacggatta
     2161 aacttctaat ttcaattaca ccctgtggat caagtccatt gattggttca tcccaaatta
     2221 atatttctgg actacctaac aatgatgcag ctatacttag acgttgtttc atgcccattg
     2281 aaaaattttt cacttttttc tttttaacat cttttaatcc taccattgat agatattcat
     2341 taagtctttc agtatctaaa ctaagccctt tcatatttgc tattaacttc aaatttttat
     2401 aagcatcaag atgaccataa aatgaaggtc ccaaaactaa tcctatccta gataatatat
     2461 ttttggaatt ctgttctacg gtttgattaa aaatagttat tttcccagaa tctggtttta
     2521 aaatccctag aatcattttg ataattgtag tttttccagc cccatttggt ccaacaaaac
     2581 catatacttt tcccttattt aaataaaatg aagtgttatg aataacttca atatctttaa
     2641 agctttttgt tagatttata atttcaacta tagccatctc tactccttag tttacagcaa
     2701 aaaattatgc ttaattctta ttgtttttgt aaacaatcag cgaacccaat actattccat
     2761 tcaacaaacc taaagaaata ccatattcaa ctggaaaatc taaaaaaatt gcaaatacta
     2821 ttccaatcat cacccctagt gaggctgctg ttgaaattac atattcattt actttcttca
     2881 ttttctttac acctcatttc ctttttgtat ataagctgta gtactatcca ccaagatcca
     2941 ttaagtactt atgatttcct gactcaacaa tcttaccacc tttcattaca aaaataatat
     3001 ccgcatcctt aatcgttgac aatctatgag ctataattat ttgagtacaa tcctgacttt
     3061 gtatatactt tgttattctt tcctcattaa tagtgtctaa tgcactagtt gcttcatcta
     3121 aaattacaat actaggatta tttattaatg cacgtgccag tgctatccgt tgcctttgcc
     3181 cacctgaaat atttgacccc atctctgaga tgatagtatt aaatttcatc ggcatagcca
     3241 tgatttcatc atagatttga actgctttac aaacttcctc tatcttttgt gaagtaactt
     3301 cgttctttaa agttatatta tcaagaatac ttcggttcaa taaaaatgaa tcctgtggaa
     3361 ctactcctaa attttgactt aatatttttt tatctatttg attaatattt acaccatcaa
     3421 ataaaatttt tcctgtatca atcttatata atcctgatag tatttttgat aacgtacttt
     3481 ttcctgaccc cgattgaccg actagtgcaa ttctctgtcc tggctcaata gtcaaattta
     3541 aattttctat tacaggagct gagtctttgg aataagagaa agataggtcc ttaatatcta
     3601 ttctaccttc taaagaacac tttttaagac cattttcaac attctcttca ttttcaagcc
     3661 agatatcatt tactctattt aagtatcctg ctgccaaaat atactacgta taagcattaa
     3721 atattgagat ttctgaacta aataaaattg atgccatcgt ttgaaatgcg acaacctcac
     3781 ccaataaaat ttttccattt aaaacattat caagtccaaa aatcaatata attataggag
     3841 cgaacaattg aaatacatta gtagctgaat tgtataaaat atgcacaata cttcgttttt
     3901 tatactttgt caatacgttt tttaaatact tagaccagtt ttcatatatt tcatcttcta
     3961 atcccgatat ttttattgaa gaaatagtat ttaatgcttc tgtttctact gagtaaatca
     4021 atgattgttc ttgtaattct ctattaaccg tatcatacat tatttttcta gtactaaaca
     4081 gaaacaaaaa attgattaaa ctcaatataa gagctataat tgataatgtt tttgaactaa
     4141 gaaacatata tattacaaca cttagaatag tcccgatatc tactactccc ccaacaactt
     4201 ggttagtaaa tagctcccta aaaccactaa gactagaaat tctgtataaa atatctcctt
     4261 ttgccctgag ttcaaaaaaa ctatatggta gtttaagcaa atgcttaaat gtaaaacttt
     4321 caatatctct actaaaaaat atattagaaa atagaattcc catactccta gccaagatag
     4381 aaataaggta caaacaaagt agagaaaata aaattaaaaa cgaggtttga aaagaaaatg
     4441 tattccctaa tgcagaatta ataaactttg aagtcattac tggtacggaa agtattatta
     4501 agtaacttat tattgaaaat agtaacgtca aaatcaatcg accttttacc tttgaaaaac
     4561 tagagaatac tcttatccat ggagaaggaa actgcgactt caaagattga taattttcgt
     4621 taggaaatga tagcagtact atattactaa aatgttttga aaactcctta aactcataat
     4681 ttatatatcc tttagaagga tccattatat agaccttatt cttttttact ttgtaaataa
     4741 ctacataatg ttgattatcc cagaatgcta ttaatggtaa cggaagttca ctaattttat
     4801 ttacatcttt aacttgatat gagccagtat caaaatttcg tttattcaat aactgtttca
     4861 agtcacctat actataacca tctctccctt tttctatatc acgtcttaaa tctagtaatg
     4921 tctctttgct tttatagaaa tgtagtatgg acaagcagca acataaacca cattctattt
     4981 gagacatttg ctcaatatta ggtacttttc tagtcatcat gtcctcttaa ctccagtaat
     5041 aaaacattaa gtaatctatc atcttgtttt cgagatattt catagacaac tccagatact
     5101 cctagcataa aagaaaatgt attcatagta ttcaaatccg tacttaattc tggtttgata
     5161 acctgagaaa cgacattatc aaaataaaaa tctatagatt cttttattaa taggttttct
     5221 tcatctttca atattgcatc aagacaactg atagtaccta cagaaccgtg acataaattc
     5281 aattctctta ttttttctac attagttaat acattttcaa ttattgataa atcattattc
     5341 ccaatattag ttttatcgaa aatttctttt ctagctaata aaatgcccgg agctccataa
     5401 caccaaaaat taggaaagga atcattatga tttcttcata tgtctttcca attttttaat
     5461 atattattga aacatttatc ttctttatat agtaattcct ctatacattt taatatatct
     5521 gtactaggat taatttcata ataatatgat aattacattg ctactccaga ataatcgtgt
     5581 gctaaacctg ttactgttat attatctaat tgtgaaatac aataattaat acactttttt
     5641 aaatgatgat aatatccatc accaaaacca aaatcggtaa aaattttgaa attttcttca
     5701 tacttggact tcctttccgt ttttatttat tgtacaataa ataaaaacgg atttaatttt
     5761 tgttgggaaa atgggaaatt atgaaatcaa aacttggcat cacacttaga aaagttcgta
     5821 aaggaaaaca aattagtcta tgctctgtag cagatgaaca tctttcaaaa tcacaaatat
     5881 ctcgttttga acgtggggag tcagagatat cttgtattcg actaatcaat attttagaca
     5941 aattacatat tactttgtag gggagttttt ggctatcgtt gctcaattgt ctgattaagg
     6001 tcctaccctt gatgaaacaa ttattatcca tgttttcttt attatagaca aagtaagaag
     6061 acgtttctcg aatgtagact ttatattttt tatgattttc ttcttccata atatccaatt
     6121 gatagttggg aatgaaaata agaccgctct gtttgacacc gaaagacacc ttgatataga
     6181 cgcccttatc aactagcttc tctatttggt tctctgcaag ttccacttca aattcacgaa
     6241 cggtatctca tttttcctta aatgtcttaa aggcttcctc aatctcttca gtggatactt
     6301 tatccttatc tcgttcttct tggaaagcat ggtactgttc ctgtaaattc tctaatcctt
     6361 ctgaagcaac gacttcctta tttttaaaat aatcttgaaa aaatttgaca tcatataatt
     6421 tcttatcact tattttttga tgacccaaac ttatcttttg attattttct tccaggataa
     6481 aagttacatt ttttgtttta agtcaatggt tagattcaat tcttttgctt ttgttattaa
     6541 atcttctaaa gaattgacac ggtttaacaa aaattctaaa cgactttcaa tctcttgctt
     6601 agcaaaatgc gttctaaaaa attcttcatc atatagatct cgtttgctga gttggcgccc
     6661 tcgaattggt tttatcatcg ttctatctgt catcaaaaaa cggctatgct tttgactaaa
     6721 atcaatctga acatgcaact gctttgcttt ctctaaaaaa tcatcaaacg atttagattg
     6781 ctgaagcaaa aaataaagac gttgtttcaa ttcaaattta tgactagatt ccttatattt
     6841 tttataatct cgaaaagatc aggattttta gctaaaactg ccttacgaaa atccttccag
     6901 aactgatggt caatctcatt agccacatcc aaacgccaag catcgatatt aaactcttca
     6961 atccaataag tcgcaacctt taaaagataa ttcttgacct ctggattggc tgtatttagc
     7021 ttaggcatat agtcctcgaa accaaaaaca tgatagggta agtctctctt attaactagc
     7081 ttttcagttg tcaatgggaa ttgttgaata tggaaccaat ccttataagc agactgttca
     7141 ccatttttga cgacattttt tcattgaaga gattgcgaac caatatgatt aaataccgca
     7201 tccagcatga ctttcatgcc acgatgatgc gcttgatcca ccagttcccg aaaggtctcc
     7261 ttgtctccaa aataacggtc aatttcaaag taatctgtcg tattgtactt gtgattactt
     7321 gtagattcaa agatgggaca aagatatagt ccagtaatac ccaagtcttg caagtaattc
     7381 atatgatcaa taatcccctg taaatcacca ccaaagaaat catcgctctt aggtgtgaca
     7441 gatgaatccc agtctaaagt cccttctggg tttaatagag cattgccatt ggcaaatctt
     7501 tcaggaaata tctgatacca taccgtattt gaaacccagt caggaacctt gcaggcatca
     7561 atctcatgaa gataaggcaa cttaaatcca ttcccaattg catgaagatt ttctagagaa
     7621 ttttccacac accctttatc gccatacaaa atattttgac cttctgtatc tctgagctca
     7681 aagagatact ggatacgtgc aaagtcaact gacacttcaa cctgccaatg gtcaaataag
     7741 gtaccagaag ttatcttgac catttctttt gtatcctgat aaaactcttc cataaagata
     7801 aaagggtccc catagtgcaa gttgatgctt tcaatgtccc ctttcttagt tcgaattcga
     7861 atatggagtt tcttatcctt ataaagatag gcatactccg actcaggcct atggtaaata
     7921 gcactcaatt ccatcaattt gtctcctaaa gtattcattc aaattttacg caaacgtttt
     7981 caaactcaat aaatccagta tactattttt gtaaactatt tgcaaggaat gtccgttgtt
     8041 aaaggaacta tcttttaaag tatacaaaaa gccttaaaaa aggctttctc tatatactaa
     8101 tcctctttcg gttttgaaaa tacttctact cgctgagcta ggactttgat ttctacaggt
     8161 aggttatctg atttatctcc gtcaacatct gactccaatt cactatctga agagatttta
     8221 atattacgcg ctttgatata ctcgatatta tcatttgcga caacatcccc ttttaataaa
     8281 tcaggaatga cggataattt ggagaatata gaggcatctt tcagaatcaa aatgttggca
     8341 tagccgtcct tgttttcttc aaagattttc ttatcagcga agtaatttgt caaaaggacc
     8401 aaaacatggc tagcttcacc aacataattt ccattttctg tctcaacctt aatgttaaag
     8461 acctgatctg tcatgacaga cttcatggta tttacagcat aggttaaaat accgaatttt
     8521 gttttgtcct ctatttcaac attgtgaatc gcctcaggca gagaaccgat actaaagata
     8581 taaccaaaat agttgtcatt tgctttaccg atatcaatct tattggttaa atcaaaatcc
     8641 agttcgtcaa ttgcgccatc gatgtcttga ttgatttcca aaagttttgt aatgaggtta
     8701 cccgtaccgc ctgggataat ccctaactta ggaatgtagt ctctctcatc aatacctgaa
     8761 atgacttcat tgacagttcc atctccacca aacacaacca ctgcatcata ctgctcacga
     8821 gaagcttctt cagcaaaatg tgttgcatcc agcgcttttt cggtaatttt ggtttcaaca
     8881 tattcaaagt attcttttgc tttattctcc agcttttctt tgtaatccaa agccttctcg
     8941 ccaccagaag tagggttgat aattaccatt gcttttttca ttgattttat ccttaatttt
     9001 aaacagaaat gtttacattt cgtcgtatgc aagtaaatgt aatcctatta tacaatgaaa
     9061 atacagaaaa gagaaatctg acgtactgga gattaatacg cttttattct attttcccat
     9121 cgcctaacta catcctttaa gggttcatcc aagtaagaat aggccttatc cttgatccaa
     9181 tcaggaatac cgtaagctgc ctctgctatg ttacaagtga ttgctgcgag agtatcactg
     9241 tcgccaccaa gtgagatggc atttcttatc gcatcttcga agtctctact ttcaagaaag
     9301 gcgataatgg cttgagggac agtttcctga catgtttcgt taaaacgata gttaggacgg
     9361 atttcatcta aagtttgaga tagattgtaa tcgtattctt tttctatata atccttaatt
     9421 cgtcttttac actctgtaag attgtcgtta attgattgct cgtactctct acaataacca
     9481 ccaaagtaaa aacgacatag aaagatagca tcagctgtag ccatagcgcc tttgacacct
     9541 tctggatgat tatgagttac ctctgcagaa agactcgtaa gtcctctaga tgatggccat
     9601 ataccagttt tcgcataaaa accacagtcc atgatccaag cacatggaga aatacgcata
     9661 gctgatccat tcccaaagct attataaggc tcacggttat cgctgtttag ccatgcatta
     9721 aaccgagcac cgtaatcagc attcggatac attctgccat atttcttcat cgcgtcaatg
     9781 aaatcgtctt tttgtccacc attcataatt gcttctgcaa cagcacaggt cataaccgtg
     9841 tcatctgtaa aaaagcagtc cttccgaaat aaaggaaagt cctttgtttt gatattgttc
     9901 cattcgtaaa cagaaccgac aatatctcca ataattgctc caagcatcag attcctcctt
     9961 gttcattttg atgcttttta tattggttat ataccatatt tattttagaa aacaacatcc
    10021 tgttggattt taaaaatttc atttttttca aaatagggtt ttaccatttc tttccaccta
    10081 gctctatgaa aattgattga ttttaaagga gatagggcat aatttcccaa tgcataacca
    10141 tcatttactt caacaacaag tgttctgcca tcgcgagtaa caccgatatc tagtccataa
    10201 gctattggcg catctttcca acatgatatc gcttcatcaa ttacacttgc atcaaattgt
    10261 gcatgataat cacctgtata gggtcgaaca tctaatacgc gaccatctaa cacaaaacaa
    10321 cgccattcag ctatgaattc tacaacctca ctaatccata taggatagtc gaaaggtaga
    10381 ccaataccta ttaaatcatg ggttccatta acaactcttc cagtaaagac ttttgaacca
    10441 gctttaggct taataaattt tccccaatta tcaggtatat tcacaatctc tcctaaaata
    10501 ccagcataaa tctttcgacc ataaaactct ttaagctcaa taggatagtc ataaaccgga
    10561 acgtttaagc ccatcatttt tagtaatgct ctagtctcca ttatataatc tacaactata
    10621 tcttcacttg ttaactcttt tatttcagaa aaagattgat ataaaataac ttcttctcct
    10681 tgtaagtagg cacctacttg agcattgtat ttattaattg aaacctcact tggtaattta
    10741 ctttgtctaa tataaacaac catttcatca ctcctatatc actagtgtta cactgatttg
    10801 taaaaaataa tagcaatttt gctcttattt ttttgagtaa atagctccca taatatcatc
    10861 gaaataatca acggtattta ggagtaattc aataacctgg gactttgtta gtcgcattcc
    10921 ccttctatct ctagcatctt ctactaaatt ttcaagtttc tctagatttt tatcatccaa
    10981 gctaatcatt attctatttt tatcggttgc cattttcatc acctcaagtt aattctatca
    11041 caggtgtaac acttgtgtca actggctttt ataatacatt agtttaaaag tggagaggat
    11101 ttttaacaca gtaactttaa atctttggta ttaaaaaatt ttcacaatat ttatagaaat
    11161 aaaatctgtc tcaaatcagt tatcaaatct agtataaatt atgagcggct actctaatac
    11221 tttccctcta aacaagaaaa agacttacac tcaaggattt tcttcccccc cttcgttata
    11281 acgttttgac tcttttacta gcaaaggtat atactcacaa ggaactttgg ttgactattg
    11341 aatctctcca acttcttctt taacatatcc ttctacatct tcaatctcta caaacattgg
    11401 gtctaagtga cacaagaaat gccaaacttc gatccctttt tttctgtaaa gaatcgcttc
    11461 accgtcttca cttccgaaaa agcttctgtc gatttcatat ccgcggcttt ctaagaagtc
    11521 ttttgcttta cgatagttcg tttctcttgt ttcgacatag gttttaactt catggttgtt
    11581 aacgacatat gcatcaattt ttgaatatcc ttcgatcact ctatcatttt tgagggataa
    11641 atttgaaatc tctttccaaa taatgtttac attttcctca ggatcgaaca taaatttaga
    11701 taaaggaaca atatttccgt taaaaataat ttccatataa tccggtatgt ttttaggatt
    11761 aaaatactcc acttcaaaac catcttctgt ttccagagtg tatcccggga tttgagctac
    11821 aaaggctttc ccatcttcta tggaatcaaa tgctactaaa tctttagaat aatcattttg
    11881 gtacaattcc aatataacca tcgataatct ctccattttc attatcaggc taatgtaaat
    11941 aagcacgtca cctgaccaat tcaggctctc tgtatcatct catcatattt cctacttact
    12001 ttacgagtcc tatacccaga acacacctta tcgaccttcg gtctcacctc gttgcattgg
    12061 ctgaacatct acttttactt cgctgatgct tcaactcgta caagcagtga taccgcctca
    12121 gcgtgatgcg tcagtgggac tcaaaaggtt cggggaacct tttgaggatt aactacgttt
    12181 ctctaataaa cttacacatt caacttgttc atcattgtcc aaacctatgt tgagattttc
    12241 ttctataatt ggtagcttaa aagtaatgga ttttagccat tgtccgttag attgtttttc
    12301 ttcataaact tgaatttcag aaatcaaagc tgaaattaac tgcctacgct ctacatcatt
    12361 catgacttta tagagcttat caaaatagat cagaacctta tatatgttat ctcctgtaag
    12421 cttttcagct tcaatagtct gtttctttgc tttcgcatca attagtgatg attctaattc
    12481 atctactttg tcatacatac gatatagtct atcatctaaa tcctgtttcc ttctcttata
    12541 atgcttatct tcaacatcta aattatctat ttcctcaatt agcttaaact ttgtagaatg
    12601 actctttctc aattcctttt ggtaattatc tatttctttt tctatttcag aggtatccac
    12661 cttcatgttg attttttctt gcatcataga agcaaatttc ggattactta ctatcttgac
    12721 aatcacctct gcaacagcat catctaacaa ttcttctcta atttgcttac tgaatgtaca
    12781 cttatgacct cttatcatct gcctatggtt acaaccatag taataaaaat ctttatactt
    12841 tgtgccatct ttctttttct tgatacactt gttcccaaac attcccactc cacatatcgg
    12901 gcattttaca attccagaaa gcaagtgtgt gcgtgtatct tttcctttat tcacatgctc
    12961 atatttcttt gcttgagatt ttagcttaac ctgagcagct tgccaaactt catcggaaac
    13021 tatagcttca tgtatccctt cagatattag atattcatct tgttcaacct gcttatattc
    13081 atttcttgta ccatgaactt tttctaaagt tcttcttcca aatgctattt tcccattata
    13141 tacaggattc tttaatatct ttcttataag acctgcatca aacaaaggat tcttaccatt
    13201 ctgtcttggg atttttctaa ttccatgatt ctctaagtat ttagatatcc cattggctcc
    13261 tatcgtagta tttacatact ggtcgaaaat cgttcttatt gcaactgcct cttcctcatt
    13321 tataaacagc ttgccgtctt caagtttata tccatacgga gcaaagccac cattccattt
    13381 tccttccctt gctttttgaa tgcgaccttc cattgtttga atacggatgt tttctctttc
    13441 tatttcagcc acagctgata aaacagaaat cattagtttc ccagcatctt tagatgaatc
    13501 aatgccatct tcaacgcaga taagattaac tccataatcc tgcattatct gaagtgtaga
    13561 aagaacatca gcggcatttc ttgcaaatct tgataactta aacacaagaa caaaagatac
    13621 tccatctttt ccagatttta tatcttccat cattcgattg aactgtattc taccttcaat
    13681 agacttgcca gacttcccgg catcttcata ctctccaaca atttcataat cgttgtaaat
    13741 agcaaaagct ttcattcgtg atttttgtgc ctctaacgaa tacccctcta tctgtattga
    13801 cgtagatact cgtgtataga ggtatacttt tattttttct tttgacatag tattaatctc
    13861 aatataattt ttctatatca tatataattt ttttaattta agtttggact atcatttcaa
    13921 gtatattata acacttttat tagtccgtct caatttgtgt ttttgccatg tcaaaactat
    13981 ttttcatctc ttgatttttt gctggcgttg gatcgggtag attatctaaa tctaaagcac
    14041 cagcatattt tgcaatcaga tttgctatta aatcagccaa tccattccag tcattgtcca
    14101 atatatacct cctctaaagt tttatatcta ataattattt gtttaattaa gttttttgac
    14161 attgacaagt gctttggatt agcaacatag gaatctcacc tccgcctcta ttccggatga
    14221 gccggcttca accttagaag tatcattatc ctcattttct tcatagcgga tagggtatcc
    14281 ctccctatat tcaaactctt acttatcgct cactttcttt ttacttagca gaactttttt
    14341 tgccgaatta ttcagccgaa agatcttgac ggataggtta ttacgctcca aaaataatta
    14401 acgtcttgtc ttggtctatt caattgttaa ggttcaaaat ttatcgagag ttattaatct
    14461 ttttaaaatt tgaccatcag aaaatattta tcttaatgta acaaaattct ataaattacc
    14521 ctcttatact taacagtgaa aagaagtctt tcttggtaac caattttgaa atagaatttg
    14581 cttatataaa aaggtcaaat tcccactgca taagtagcag tgaaaattag accctcttgg
    14641 taactgtcat ctaaaagtct tctagcattt ctttaatttt ctaatcgcct ttaaagtgtc
    14701 atatttatat ttttttatct ctggcatact ttgatacctt tttagactta aagtctttaa
    14761 tagtgccttt ccacctcttt ttatctataa agattctcct acatcataat tcattttttt
    14821 atttaaacct ttctgtctta gtttgtcttt atcttcttca taccatttta agattgtcac
    14881 atagtggttt tgataggtct taccactgct ttccatgtat ctggatagtt tatttatcat
    14941 tatatctgtg tgtgagttta atttttcttt tagattttta tattcttctt tgcttaacct
    15001 tacatttttg aattctccat aaaaaatggg ggtggacttt ttatctatct ctccctctct
    15061 ctctttatct atctctatat ctttccatgt aattccaatc tggagtacct ctactgtcta
    15121 tcggtaattt aattttgata tctggcaata ctgtgctaga tatttgatct ttatattcag
    15181 tattttttaa agcttgccta ataattgaag ttaaatagaa tgctacttct ttattcaatt
    15241 ctttattttt taattttaaa caatgaattt tcatatctag gcttgcttta tatttatgat
    15301 aaaagactgc tcctaaaaat gaaacagata taaaattttc aaaaactcta taatttttat
    15361 catctatatc ttcgtagtaa cctaagatac cattgtcaat atttgtagca ctaattctag
    15421 gagtttttcc atcgagtaaa tatctttttg gaatagatga gcctgttggt acttgactcg
    15481 atttcccctt tttttcggta ataaatattt ctttttattt tgttgtctga tatttttcct
    15541 acctgtcctt tgtaggatga gtattttcta gattttcttg aataactttt tacttgaagt
    15601 tttagctttt gaactagtcg ttgtactttc tttttgttta ttatcagtcc tgatcttttt
    15661 aatattgctg ttattctcta tatcctattt ttcattcatg atattctttt actaatttta
    15721 tcttaaattc tgtgctgtat ttgccattaa aaaactgacc tcctttagtt agttttttgg
    15781 cctaactttt gagggtcagt tcaaaatttg cgacttttaa atgaattcca atattcaatt
    15841 attaagagct aacatggtgc ttgccaatag gaatcattag aggcgaattg gaaatagggt
    15901 cacgtataat ttttgcttca agattaaaga tatctttaac tagtttatca tttagtatat
    15961 cttcaggctt tccctctgca acaagtttac cttctttaat tgcaaatagg taatcagcgt
    16021 atcttgctgt tagatttata tcgtgcaaaa tcatgcaaat ggttgtctta tatttttggt
    16081 ttagatcagt caagaggtct aatagttcta tttgatatga gatatccaag taagtagttg
    16141 gctcatctaa aagtaggata cttgtatctt gggctagggc tagagctatc catactcttt
    16201 gcctttgacc cccagaaagt tcttcaacta ggttatttgc tagatcttca acattggcct
    16261 taaccattga tctgtttatt atttcaaggt catcttttcc aagactctta aaaggctttc
    16321 tgtaggggaa acgaccacgg cttacaagat cagctactgt tattgattca gggattattg
    16381 gagattgagg taatatagct atgtgttttg ctaaatcttt ttctttataa gaattaattg
    16441 atttattatc aagcaatact tctccctcta atggctttat aagtcgagac aaggttttaa
    16501 tgagtgttga tttcccacaa ccatttgacc caataataac tgatattttt tcttcaggta
    16561 tttttatatt tatattttcc aagattattt tttcatcata accgcaggta agattatttg
    16621 accacagacc tttcattata tattcctcct gttcattttt attagtaagt atattaagta
    16681 tggtgaacct aacaagccag ttacaacacc tactggatat ctagctggta aaatattttg
    16741 agagaatatg tctgataaca aaactagtaa aattccaacc aatccagcta atattgggct
    16801 tcttttcttg ccaatattta aggctatggg accagctaaa aaagatatac aagctattgg
    16861 tcctgtaatt gaagtagaaa aagcagttaa agatacagcg caaaaaatta aaacaagcct
    16921 tgaaagctcg ggatttgctc caagtccgat tgctatttct tcaccaagtt caataatttc
    16981 tagtctttta ttaaaaaata aaactaatat agtagcaata atacttacta ttagaacaag
    17041 aggtatgtca tctaactttg taaaagataa agagccactg agccatctca taacttcttg
    17101 taattcatat cttgctactt tcaacaataa aaatgaggtg cctgctcttg tgacagcttg
    17161 aaaaccaata cctaatatta tcagtcttgc tgctgaaaaa ccatcttttt tagctagtaa
    17221 aaataatatt aaagatgatg ttagtccaca agttattgaa ataattccag tagttaaact
    17281 atttgttttt aataccaata tgcaaaagac cgctgcaata gatgaagaac ttgtgacacc
    17341 gattatatca ggacttgcaa gaggatttct taacatagtt tgaaagataa atcctgccaa
    17401 tccaaaagac cagccagcta taattcctgc taataatttt ggtaatctaa tttccataat
    17461 cgaaaaacta gctccaggaa cagtttcact atttaagact ttaatcaaag ttgaaaaaga
    17521 ataactttca tctccgataa gtaaaatgaa aaatgataga ctgattatta ttaataaaaa
    17581 tagtgaggaa aatagtgtta ttctattttt tcttttttga atacctataa ttaaattttg
    17641 cattagttat taacccctct atttttcata gttacataaa taagtactgg acccccgatt
    17701 attgcagtaa ttatccctac ttcaatttca cctggtttac ctaacatacg gccgattata
    17761 tcacatataa gcaagagctc tgcacctata aaagatgaag aaatggtcat tgtgcgtata
    17821 tctttgctta taaataagcc acaaaagtga ggaactataa gacctacgaa gccaataggt
    17881 ccaccaattg cagtaatact tgaacataaa agcacacttg caattattgc aagtgatctt
    17941 atcctattaa cattaactcc aagaccaaca gccatttcat cacccatagc taaagcgttt
    18001 aaatctgatg aaataaatat agctatcaag tgacctaaaa ttataaaagg tagtagtgta
    18061 gatatagaag ataatgtagc tgctccaagg ctacctattt gccaaaatct aaatttgtct
    18121 aagacgttat tattcggtaa aattaaaaaa cttacaaaac tgcttaaagc catactaaca
    18181 caagttcctg ataaggctag ttttataggg gtaaggcctg cttttccgct tacagcaatc
    18241 gcgtatacaa aaattgcact tactaagcca ccaatgattg caaaacttat atggcttatg
    18301 cttgatgaaa ttcctaaaaa agaaagacca attactacac taagacttgc tcctgtgttt
    18361 ataccgagta tacctggatc agctattggg tttctagtaa ctgattgcat caatacaccg
    18421 cttatggcaa gactagaacc tgctaaaatt gcaaaaatag ttctaggtat tcttttatat
    18481 ataattgatt taataaaatc atcatttgta ttgcccattc caaaagttgc taaaaaatct
    18541 ctgatattaa tttcttttgt tccaagcttt aatgacaaaa atattgtaat aagaagacct
    18601 aggcagatta caaaaattat gcctaggttt atttgttttt tatttcgcat ttttgcatgc
    18661 atttcctaaa agatttaggt attcttcaat agtatagttt attgaaagtg gtgttggagt
    18721 gcatgaggct gctaacggtg tattatctgg aattacagca acggcaccat ttttaattgc
    18781 atttatttta cctaaaagag gatctttttg taaagcttca agagttttat catcaccata
    18841 agttatgatt acatcagcat catttatctt atttgcttct tctgcagaaa tttcctttgc
    18901 aaaactatct tcactctcaa attcttttaa tgattcaggg aaaactagac ctaaatctgt
    18961 taaataattt gctcttggat ctttgctagt ataaatccag aattttgatg tatctgcagc
    19021 attaatcata gtaaataata ctttttttcc tttgattttt cctttgattt ctggatgttt
    19081 ttctaattct ttggatatac gagcttcagt atttttgatt aactcatcac cttctttttc
    19141 catacctaag gcttttgaat caattttaat catatctctc cataaagttt gccaaggttt
    19201 agatttgtat gctgctacag gagcaatttt tgatagagtg tcataatctt ctttagttat
    19261 accagaataa cctgctaaga taacatctgg tttagaattt gatattgctt caaagttaag
    19321 tccatccaaa tcgtcaaata ggttagcttt accatttagt tctttgattt tttcttctgt
    19381 ccatggtaaa actcctttat cagcacttac accgtaattt gcttttgaaa atccaacagg
    19441 aactattcct aaagctaatg ctacatcatg atttccccaa gcaatagttg caactctttc
    19501 aggtttttta tctaatatag tttgaccgaa agcatgatct aaaactattt tatcaggcgc
    19561 atgctcttta gaagtatttt cttcattttt aacagaatta gaagaacaag cgctaaaaac
    19621 tatacacata gctaaaatag ctattagaaa aaatttgttt ttcataaaaa ctccttaaac
    19681 atatttcaag tctattgtat cgataataat tatcattgtc aatagataca gttacaaatt
    19741 taataatata attttttcaa aaaagg
//
LOCUS       DAVBEO010000044        18992 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 009
            SAMEA1678075-rid20185393.denovo.044, whole genome shotgun sequence.
ACCESSION   DAVBEO010000044 DAVBEO010000000
VERSION     DAVBEO010000044.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678075
            Sequence Read Archive: ERR226392
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18992)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18992)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980207.1
            Genome Coverage       :: 150x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:50:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 72 of 147
            Pseudo Genes (incomplete)         :: 72 of 147
            Pseudo Genes (internal stop)      :: 42 of 147
            Pseudo Genes (multiple problems)  :: 32 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18992
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678075-rid20185393.denovo.044"
                     /strain="KS 009"
                     /db_xref="taxon:1313"
     gene            complement(21..1376)
                     /gene="rlmD"
                     /locus_tag="VQ543_001581"
     CDS             complement(21..1376)
                     /gene="rlmD"
                     /locus_tag="VQ543_001581"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HET2612279.1"
                     /translation="MNLKVKQKIPLKIKRMGINGEGIGFYQKTLVFVPGALKGEDIYC
                     QITSIRRNFVEAKLLKVNKKSKFRIVPSCTIYNECGGCQIMHLHYDKQLEFKTDLLHQ
                     ALKKFAPAGYENYEIRPTIGMQEPKYYRAKLQFQTRKFKNQVKAGLYAQNSHYLVELK
                     DCLVQDKETQVIANRLAELLTYHQIPITDERKVLGVRTIMVRRARKTGQVQIIIVTNR
                     QLNLTQLVKELVKDFPEVVTVAVNTNTAKTSEIYGEKTEIIWGQESIQEGVLNYEFSL
                     SPRAFYQLNPEQTEVLYSEAVKALDVDKEDHLIDAYCGVGTIGFAFAKKVKTLRGMDI
                     IPEAIEDAKRNAKRMGFDNTHYEAGTAEEIIPRWYKEGYRADALIVDPPRTGLDDKLL
                     DTILTYVPEKMVYISCNVSTLARDLVRLVEVYDLHYIQSVDMFPHTARTEAVVKLIKK
                     V"
     gene            1414..2190
                     /gene="recX"
                     /locus_tag="VQ543_001582"
     CDS             1414..2190
                     /gene="recX"
                     /locus_tag="VQ543_001582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000705102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination regulator RecX"
                     /protein_id="HET2612280.1"
                     /translation="MKITKLEKKKRLYLMELDNGDKCYITEDTIVRFMLSRDKVISEE
                     ELKEIQDFAQFSYGKNLALYHLSFKARTEKEVREYLKKYDIDKNIVSQVIANLKEDKW
                     INDGQYAYAIINANQLSGDKGPYVLTQKLAQKGISKSTIEEILNDFDFSEVAQRVANK
                     LLKKYEGKLPARALQDKIIQNLTNKGFSYFDAKIAFDELDSQVDEETTQELIFKELDK
                     QYTKYARKYEGYKLKQRLTQVLARKGYDFSDIASALREYL"
     gene            2279..2812
                     /locus_tag="VQ543_001583"
     CDS             2279..2812
                     /locus_tag="VQ543_001583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000775318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF402 domain-containing protein"
                     /protein_id="HET2612281.1"
                     /translation="MKLPKEGDFITIQSYKHDGSLHRTWRDTMVLKTTENAIIGVNDH
                     TLVTESDGRRWVTREPAIVYFHKKYWFNIIAMIRDNGTSYYCNMASPYYLDEEALKYI
                     DYDLDVKIFTDGEKRLLDVEEYERHKRKMNYSDDLDYILKEHVKILVDWINNGRGPFS
                     EAYVNIWYKRYVELKNR"
     gene            complement(3252..4008)
                     /locus_tag="VQ543_001584"
                     /pseudo
     CDS             complement(3252..4008)
                     /locus_tag="VQ543_001584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000567550.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="epoxyqueuosine reductase QueH"
     gene            complement(4146..5768)
                     /gene="groL"
                     /locus_tag="VQ543_001585"
     CDS             complement(4146..5768)
                     /gene="groL"
                     /locus_tag="VQ543_001585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018166362.1"
                     /note="60 kDa chaperone family; promotes refolding of
                     misfolded polypeptides especially under stressful
                     conditions; forms two stacked rings of heptamers to form a
                     barrel-shaped 14mer; ends can be capped by GroES;
                     misfolded proteins enter the barrel where they are
                     refolded when GroES binds; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chaperonin GroEL"
                     /protein_id="HET2612282.1"
                     /translation="MSKEIKFSSDARSAMVRGVDILADTVKVTLGPKGRNVVLEKSFG
                     SPLITNDGVTIAKEIELEDHFENMGAKLVSEVASKTNDIAGDGTTTATVLTQAIVREG
                     IKNVTAGANPIGIRRGIETAVAAAVEALKNNAIPVANKEAIAQVAAVSSRSEKVGEYI
                     SEAMEKVGKDGVITIEESRGMETELEVVEGMQFDRGYLSQYMVTDSEKMVADLENPYI
                     LITDKKISNIQEILPLLESILQSNRPLLIIADDVDGEALPTLVLNKIRGTFNVVAVKA
                     PGFGDRRKAMLEDIAILTGGTVITEDLGLELKDATIEALGQAARVTVDKDSTVIVEGA
                     GNPEAISHRVAVIKSQIETTTSEFDREKLQERLAKLSGGVAVIKVGAATETELKEMKL
                     RIEDALNATRAAVEEGIVAGGGTALANVIPAVATLELTGDEATGRNIVLRALEEPVRQ
                     IAHNAGFEGSIVIDRLKNAELGIGFNAATGEWVNMIDQGIIDPVKVSRSALQNAASVA
                     SLILTTEAVVANKPEPVAPAPAMDPSMMGGMM"
     gene            complement(5784..6068)
                     /gene="groES"
                     /locus_tag="VQ543_001586"
     CDS             complement(5784..6068)
                     /gene="groES"
                     /locus_tag="VQ543_001586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone GroES"
                     /protein_id="HET2612283.1"
                     /translation="MLKPLGDRVVLKIEEKEQTVGGFVLAGSAQEKTKTAQVVATGQG
                     VRTLNGDLVAPSVKTGDRVLVEAHAGLDVKDGDEKYIIVGEANILAIIEE"
     gene            complement(6338..6733)
                     /locus_tag="VQ543_001587"
     CDS             complement(6338..6733)
                     /locus_tag="VQ543_001587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000282444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HET2612284.1"
                     /translation="MYNKVIMIGRLTSTPELHKTNNDKSVARATIAVNRRYKDQNGER
                     EADFVNMVLWGRLAETLASYATKGSLISVDGELRTRRFEKNGQMNYVTEVLVTGFQLL
                     ESRAQRAMRENNAGQDLADLVLEEEELPF"
     gene            complement(6811..7572)
                     /locus_tag="VQ543_001588"
     CDS             complement(6811..7572)
                     /locus_tag="VQ543_001588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HET2612285.1"
                     /translation="MAKNVVITGATSGIGEAIARAYLEQGEDVVLTGRRIDRLEILKS
                     EFAVSFPNQTVWTFPLDVTDMVMVKTVCSDILETIGRIDILVNNAGLALDLAPYQDYE
                     ELDMLTMLDTNVKGLMAVTRCFLPAMIKVNQGHIINMGSTAGIYAYAGAAVYSATKAA
                     VKTFSDGLRIDTIATDIKVTTIQPGIVETDFSTVRFHGDKERAASVYQGIEALQAQDI
                     ADTVVYVTSQPRRVQITDMTIMANQQATGFMIHKK"
     gene            complement(7605..8231)
                     /locus_tag="VQ543_001589"
     CDS             complement(7605..8231)
                     /locus_tag="VQ543_001589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4479 and tRNA-binding domain-containing
                     protein"
                     /protein_id="HET2612286.1"
                     /translation="MIFTYNKEHVSDVLMVIVKNSGDAKLNVERKGKVARVFLKENGE
                     TVAWNIFEVSSLFEIAERGQVFLSDEQVARLNQELQAEGFTEEIVNDKEPKFVVGEIV
                     EMVAHPDSDHLNICQVAVASDKIVQIVAGAPNARVGLKTIVALPGAMMPKGNFIFPGE
                     LRGEKSFGMMCSPRELHLPNAPQKRGVLELSEDQVVGTPFDPAKHWTA"
     gene            complement(8247..8564)
                     /locus_tag="VQ543_001590"
     CDS             complement(8247..8564)
                     /locus_tag="VQ543_001590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000615765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HET2612287.1"
                     /translation="MIQPASLEELASLVEKAGKKVFLFVADWCGDCRYIYPALPEIEE
                     TNPEFTFIRMDRDQYMDLAKLWDVYGIPSLVVLEKDKEIGRFVNRDRKSKEQINDFLA
                     GLK"
     gene            complement(8561..8860)
                     /locus_tag="VQ543_001591"
     CDS             complement(8561..8860)
                     /locus_tag="VQ543_001591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001013971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4651 domain-containing protein"
                     /protein_id="HET2612288.1"
                     /translation="MNGMKAKKMWMAGLALLGIGSLALATKKVADDRKLMKTQEELTE
                     IVRDHFSDMGEIATLYVQVYESSLESLVGGVIFEDGRHYTFVYENEDLVYEEEVL"
     gene            complement(9145..9336)
                     /locus_tag="VQ543_001592"
     CDS             complement(9145..9336)
                     /locus_tag="VQ543_001592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000291825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein"
                     /protein_id="HET2612289.1"
                     /translation="MYYSVDDVVSNAFKKRMILDSFFAFNCSGTMKVSTWVYDKGEWY
                     YVSSSGSMIANDWVKDNGK"
     gene            complement(9497..10171)
                     /locus_tag="VQ543_001593"
     CDS             complement(9497..10171)
                     /locus_tag="VQ543_001593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2612290.1"
                     /translation="MKKKAFGIVLLVLAAWILLQGNFGIPSLDGKIWPLLGIVFFAYK
                     SIESILRRHLTSAVFTGLLALIIANYAYDLLPVTNHSLIWASILVVLGVGYLTHSSKF
                     WNEKKWWYNGKKTVVTDKEVAFGSGTFYKQDQDLVDDQVEVAFGDAKIYYDNAEMLGD
                     FATLNIEVAFGNATVYVPQHWRVDLKVETSFGAAKADAPVAPTSKTLTIRGDVAFGKL
                     EIVYVK"
     gene            complement(10177..10623)
                     /locus_tag="VQ543_001594"
     CDS             complement(10177..10623)
                     /locus_tag="VQ543_001594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000776610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET2612291.1"
                     /translation="MKLRIEIDGNLEETEIVIKTPTLTDEIADLQRLLQESKAPRLTF
                     YKGTGEYYLDLSEILFFETEGSKIYAHNQKEAYEVRLKLYELESILPRYFNRVSKSTI
                     ANIRQIYSVDKSFSGTGTISFYQTHKEVHVSRHYQSLLKENLRNMR"
     gene            complement(10725..11240)
                     /locus_tag="VQ543_001595"
     CDS             complement(10725..11240)
                     /locus_tag="VQ543_001595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000800937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HET2612292.1"
                     /translation="MKNYQEWYRNISSRLTSRPILLFLLRSFNRLMTVAMPLVYLILL
                     VTTYLQLGLGQQVGVCVLIPASGFVALSLFRKKINHPRPYETWDICPLLDKDSSGRSM
                     PSRHVFSATIISMACLHASLPIGLVCLIFSALLGLVRVLGGVHYPKDVLVGYACGLVW
                     GFLFFLFLHVS"
     gene            complement(11237..11599)
                     /locus_tag="VQ543_001596"
     CDS             complement(11237..11599)
                     /locus_tag="VQ543_001596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2200 family protein"
                     /protein_id="HET2612293.1"
                     /translation="MSQKLYNMKFAAVYLALIAKVERKGGKAESVHQVTSWLTGYEVS
                     DVLACLDRDVTYGDFFRQAPYYVPERIAITGKICSVRIEEIDDPLMQEIRRLDKLVDW
                     LAKGKTSQQVLEKYEKHK"
     gene            complement(11665..13524)
                     /locus_tag="VQ543_001597"
                     /pseudo
     CDS             complement(11665..13524)
                     /locus_tag="VQ543_001597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001850459.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein/permease"
     gene            complement(13541..14011)
                     /locus_tag="VQ543_001598"
     CDS             complement(13541..14011)
                     /locus_tag="VQ543_001598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000360543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HET2612294.1"
                     /translation="MDKPMLVFKRFGHQIHLMVQKEAKRCGIEFMGGPQGQVVHFLDN
                     REKNQDLVLIKDIEQELNITKSVASNLVKRIVQNGLVELEASPVDKRAKFVRLTDKAR
                     SQMQQVKAFFERIDKQLMEDIDEDELLIFEKVLGQLQANIKGIGGENKEISQKN"
     gene            complement(14135..14851)
                     /locus_tag="VQ543_001599"
     CDS             complement(14135..14851)
                     /locus_tag="VQ543_001599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015604432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HET2612295.1"
                     /translation="MGRKWANIVAKKTAKDGANSKVYAKFGVEIYVAAKKGDPDPESN
                     SALKFVIDRAKQAQVPKHIIDKAIDKAKGNTDETFTEGRYEGFGPNGSMLIVDTLTSN
                     VNRTAANVRAAFGKNGGNMGASGSVSYLFDNKGVIVFGGEDADAVFEQLLEADVDVDD
                     VEAQEGTITVYTAPTDLHKAIVALRESGIEEFQVTELEMIPQSEVELSGEDLETFEKL
                     YSVLEDDEDVQKIYTNVDGF"
     gene            complement(15732..17141)
                     /gene="ply"
                     /locus_tag="VQ543_001600"
     CDS             complement(15732..17141)
                     /gene="ply"
                     /locus_tag="VQ543_001600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cholesterol-dependent cytolysin pneumolysin"
                     /protein_id="HET2612296.1"
                     /translation="MANKAVNDFILAMNYDKKKLLTHQGESIENRFIKEGNQLPDEFV
                     VIERKKRSLSTNTSDISVTATNDSRLYPGALLVVDETLLENNPTLLAVDRAPMTYSID
                     LPGLASSDSFLQVEDPSNSSVRGAVNDLLAKWHQDYGQVNNVPARMQHEKITAHSMEQ
                     LKVKFGSDFEKIGNSLDIDFNSVHSGEKQIQIVNFKQIYYTVSVDAVKNPGDVFQDTV
                     TVEDLRQRGISAERPLVYISSVAYGRQVYLKLETTSKSDEVEAAFESLIKGVAPQTEW
                     KQILDNTEVKAVILGGDPSSGARVVTGKVDMVEDLIQEGSRFTADHPGLPISYTTSFL
                     RDNVVATFQNSTDYVETKVTAYRNGDLLLDHSGAYVAQYYITWDELSYDHQGKEVLTP
                     KAWDRNGQDLTAHFTTSIPLKGNVRNLSVKIRECTGLAWEWWRTVYEKTDLPLVRKRT
                     ISIWGTTLYPQVEDKVEND"
     gene            complement(17152..17484)
                     /locus_tag="VQ543_001601"
     CDS             complement(17152..17484)
                     /locus_tag="VQ543_001601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2612297.1"
                     /translation="MYICIDNSMTKNKELVKNQTFKPALLTRRLVKNFMIEEPDLARN
                     PFTRPTLIDLDKVFMLDNTVIPTSYLARRRRNVSEELYEEILDYLVQPRLISLNKSEF
                     MQLNPGTY"
     gene            complement(17555..18163)
                     /locus_tag="VQ543_001602"
     CDS             complement(17555..18163)
                     /locus_tag="VQ543_001602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000083609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2612298.1"
                     /translation="MSQSSYLSPLLWLKKEADKEKMSATQCQIFFFYYQMFELLFARE
                     SDMKDLCLGTKGFYFSQLEKNLLSGVSRFLKNLEGKVTLKANQEVSARKALFLALTTS
                     QSDWQELAPVFDFYQTIGRLENPSLLSSQDRQHLMWIYQSALEKDYIVKVIGDKHFVL
                     KRQDATKLTARQTQTLEILSQSEDLVNPVYVTLGEKGVLLLD"
     gene            complement(18176..18634)
                     /locus_tag="VQ543_001603"
     CDS             complement(18176..18634)
                     /locus_tag="VQ543_001603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000186958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4231 domain-containing protein"
                     /protein_id="HET2612299.1"
                     /translation="MTPEEMYLTERLDVQIAHFLKKSVQHRRRYKVLKITEIVAGFLI
                     AVFCAIPMPGDRYRLISVALSSLGLLCEGIINLYNAKENWISYQKTAQLLEKEKFLYQ
                     CQTEKYAGKTKAFALFVKTCEGLISEEINQWESIQSKEVAASADAPVKKE"
     gene            18759..18992
                     /locus_tag="VQ543_001604"
                     /pseudo
     CDS             18759..18992
                     /locus_tag="VQ543_001604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
BASE COUNT         5595 a         4213 c         3459 g         5725 t
ORIGIN      
        1 atgttttgtc aacacctttt ttaaactttt tttattaatt ttacaacagc ttcagttcga
       61 gctgtatgtg ggaacatatc gaccgactgg atataatgaa gatcatagac ttctactaag
      121 cgtaccaaat cacgagccaa ggtcgaaaca ttacaagaaa tataaaccat tttttctggt
      181 acataagtaa gaatagtatc taataactta tcatccagac ctgtacgtgg tgggtcaaca
      241 atcaaagcat ctgctcggta gccttccttg taccaacgag gaataatctc ttctgccgtt
      301 ccagcttcat aatgagtatt gtcaaatccc attcttttag catttcgctt ggcatcttca
      361 atagcttctg gaataatatc catacctctg agtgttttta ctttctttgc aaaggcaaat
      421 ccaatcgttc caactccaca ataagcgtca atcaaatggt cttctttatc aacatccagc
      481 gcttttactg cttcgctata gaggacttct gtttgctcag gatttagttg ataaaaagct
      541 cgaggggata gtgaaaattc ataattgagt acaccttctt gaatactctc ttgcccccag
      601 ataatctctg tcttttcacc atatatctca ctggttttag ctgtatttgt attaacagct
      661 actgtcacaa cttctgggaa atctttaacc aactctttta ccaattgagt taaattaagc
      721 tggcggtttg taacaataat aatctgaacc tgtccggtct ttctcgcgcg tcggaccata
      781 atagtacgga cacctagaac ttttctctca tccgtgattg gaatctggtg ataagtaagt
      841 aattctgcta agcgattagc aatcacttgg gtttccttat cttgtaccag gcagtctttc
      901 aactctacta aatagtgaga gttttgtgca tataagcccg ccttgacctg atttttaaat
      961 tttcgagtct gaaattgtaa cttagctctg taatattttg gttcctgcat tccaatagtt
     1021 ggacgaattt cataattttc atatcctgca ggagcaaatt ttttcagcgc ttgatgaagt
     1081 aagtccgtct tgaactccag ctgcttatca taatgcaggt gcatgatttg gcagcctccg
     1141 cattcattat aaatagtaca agatggcaca attcgaaatt tagacttctt gttgaccttc
     1201 agtaattttg cttcaacaaa gttgcgtcta atagaagtaa tctgacaata gatatcttcg
     1261 cctttgagag ctcctggtac aaagactaat gttttttggt aaaagccgat tccctcaccg
     1321 ttaattccca tgcgcttgat ttttaatggt attttttgtt tcactttcag attcataccc
     1381 ctatcttatc acattttgag ttataataga gctatgaaaa tcacaaaact tgaaaagaaa
     1441 aaaagactct atctgatgga gcttgataat ggcgacaaat gctatatcac cgaagataca
     1501 attgttcgtt ttatgttatc gagagataag gtgataagcg aagaggaatt gaaagagatt
     1561 caagactttg ctcaattttc ttatggtaag aatctggccc tctaccactt atcctttaaa
     1621 gcacgcactg aaaaagaagt cagagaatat ctgaaaaaat acgatattga taaaaacatc
     1681 gtttctcaag ttattgctaa tcttaaagaa gataagtgga ttaatgatgg tcagtacgct
     1741 tatgctatca tcaatgccaa tcaactttca ggagacaagg gaccttatgt actgactcag
     1801 aaattagcac aaaaaggaat ttcaaaatct actatagaag aaatcttgaa tgattttgat
     1861 ttttcggaag ttgctcaacg tgtagccaat aaactattga aaaaatatga gggaaaactt
     1921 ccagctcgtg ccctgcaaga taagattatc cagaacttga ctaacaaggg cttctcttat
     1981 tttgatgcta aaattgcctt tgacgaattg gatagtcaag ttgatgaaga aacgactcag
     2041 gaactcatct tcaaggaact tgataagcaa tatactaagt atgcccgaaa gtatgaagga
     2101 tacaaactga agcagcgttt aactcaagtt ttagcacgaa agggctacga tttttcggat
     2161 atagcaagcg ctcttagaga atatctttaa tatttccaag tgaaattcac agattttagg
     2221 taattttatg gtacaatagt aaatgataaa cttataaatt gtagaaagtt ggttagttat
     2281 gaagcttcca aaagaaggcg actttattac aattcaaagt tataagcatg atgggagtct
     2341 ccaccgaact tggcgggaca ccatggtact aaaaacaaca gaaaacgcca ttattggtgt
     2401 caacgatcat acacttgtta ccgaaagtga tggtcgtcgt tgggtcactc gagaaccggc
     2461 tattgtttac tttcacaaga aatattggtt taatatcatt gccatgattc gtgataatgg
     2521 aacttcttac tattgcaata tggctagccc ctactatctg gatgaagaag cactgaagta
     2581 tattgattac gatttggatg ttaaaatttt tacagatggg gaaaaacgtc tcttggacgt
     2641 tgaagagtac gagcgtcaca aacgcaaaat gaattattct gatgacttgg actatatttt
     2701 aaaagaacat gtcaaaattc ttgttgattg gattaacaat ggacgtggtc ctttctcaga
     2761 agcctatgta aacatttggt acaagcgcta tgtagaacta aagaatcggt aaagttgtca
     2821 aaggtcagga acaaaatcct gaccttgttt ttttggtagt ataaaataaa ttgtgtaaac
     2881 acaaaaagga ataaatccat tatagcagag ttacaacaca tttctataaa gaaatttatt
     2941 cctacgactc agtttggcat gcttaacttc ctaactcaaa aacaaagcat cgattaattt
     3001 atccgttctt cttttgaaac agatttgaac tgataattgc tcgttttaat ttaagaagct
     3061 cttttgagca aaacttcatt tttttaagag tccaacaatt tctgtctatc gcttttctac
     3121 tagcaaaaaa cctcccttga ggcaagtttt catttatata tctaatttcg taacagtata
     3181 gtaaaatgaa ataaggacag tcaaatcgat ttctaacaat gttttagaag tagaggtgta
     3241 ctattctagt ttcaatctac tataaatttg atatgagaat agtctttctc aacatcctta
     3301 tccaacaagc atgctgtggc gtccttctta acttgaacca ggtcaatatt ctgggcttgg
     3361 gctgccatag acgcagccac aataacattg acgatagata tcatactcct cacacatctc
     3421 tactgaacgt ttgtagcctt gatttttctt gaaatcgttg ggaagatagt gggtcgtgta
     3481 aattttttgc acatcgattc cgatgctatt gatggtttga gaattcttat gaggactgat
     3541 ggtcaaggct gaaccaaagt agtcaaagcc caagtccata gccacttgcg ctgttttatc
     3601 cagtcggtag tcaaaacaaa ccttgcaacg gtcgccacct tcgggctcct cctctagtcc
     3661 cctaactagt tttcggtatt aattgggttc gtagggagct tctaggtact gaaccgtatt
     3721 tcctgtccga tcattaaaat cactaacaaa tttcttgatg acatagaccc gcttatggta
     3781 ttctactttg ggatggatat tagaattggc aaaatagatg gtcacatctg catacttggt
     3841 caaatattct agtgtatagg tactacaagg ggcacagcaa acatgcacga gaatggttgg
     3901 ccgctgctca tttttctccc atgcttgtac cattttctgc atgacacggt cataattaat
     3961 cttctgattg gggggcatct tgcacagaat ttcttctaca tcgatcatgt tcttctcctt
     4021 tttctagtct tattttatca tataagttag aagagctcaa atcaatttag aagtgaatat
     4081 tataaaaaga agggttagtc attccctcct tttgtgtttt ttataagttg ttttctatag
     4141 aaagcttaca tcatcccgcc catcatactt ggatccattg ctggagctgg ggctactggt
     4201 tctggtttat tggctacgac tgcttctgtt gtcaaaatca agctggctac agatgctgca
     4261 ttttgtaggg ctgaacgact cactttaact ggatcaatga taccttgatc aatcatgtta
     4321 acccactcgc cagttgctgc gttgaatcct ataccaagct cagcattttt caaacgatcg
     4381 ataacgatag atccttcaaa tcctgcattg tgagcaattt gacgaacggg ttcttccaaa
     4441 gcacggagaa caatattacg tcctgttgct tcatctcctg tcaattccaa ggtagcaaca
     4501 gctggaatca cattggcaag agctgttcca ccacctgcaa caataccttc ttcaacagct
     4561 gcacgagtag cgttgagggc atcttcaatg cggagtttca tttctttcaa ctcagtttca
     4621 gttgcggctc cgaccttaat aaccgctaca ccacctgaca atttggccaa gcgttcttgc
     4681 aatttttcac ggtcaaattc agaagttgta gtttcgattt gagacttgat aaccgcaaca
     4741 cggtgagaaa tcgcttcagg atttcctgca ccttctacaa taaccgtgct atctttgtcc
     4801 acggtcactc tcgctgcttg accaagagct tcaattgtcg catctttcaa ctcaagacca
     4861 aggtcttctg tgataactgt tccgcctgtt aagatggcga tatcttcaag catggctttg
     4921 cgacggtcac caaaaccagg tgccttgact gctactacgt tgaaggttcc acgaatcttg
     4981 ttcaaaacaa gagttggaag agcctcgcca tccacatcat ccgcaataat caagagtgga
     5041 cgattgcttt ggagaatgct ttccaaaagt ggcaagattt cttggatatt ggaaattttc
     5101 ttgtctgtaa tcaaaatgta cggattttca aggtcagcca ccattttttc gctatcagtc
     5161 accatgtact gtgaaaggta accacggtca aactgcattc cttctacgac ttcaagctct
     5221 gtttccatac cacgtgactc ttcgatggtg atgacaccgt ctttgccaac tttttccatt
     5281 gcttcagaga tgtactcacc aactttttca gaacgagaag atacggctgc aacttgagcg
     5341 atagcttctt tattggcaac agggatggcg ttgtttttca aagcttcaac tgctgcggca
     5401 actgctgttt caatcccacg acgaataccg attggatttg cacctgctgt gacgtttttg
     5461 attccttcac ggacgattgc ttgggtcaaa acagttgcag ttgtagttcc atcacctgcg
     5521 atatcattgg tttttgaagc cacttctgat accaatttgg cacccatatt ttcaaaatgg
     5581 tcttctaatt caatttcttt ggcaatagtc acaccgtcat tggtaatcaa tggtgagcca
     5641 aatgattttt caagaacgac attgcgacct tttggtccca aggttacttt aacagtgtct
     5701 gcaaggatat cgacaccacg gaccatagct gaacgggcat ctgatgaaaa tttaatttct
     5761 tttgacatac ttactttctc cttctattct tcaatgattg ccaagatgtt agcttcgcct
     5821 acgatgatgt acttttcatc gccatctttg acatcaagac ctgcgtgggc ttcaactaag
     5881 acacggtctc cagttttaac acttggagca accaagtcac cgttcaaggt acgaacacct
     5941 tgtccagtag ccacaacttg ggctgttttg gttttttctt gggctgaacc tgcgagaaca
     6001 aagcccccaa cggtttgttc tttttcttct atttttaaga ccacacggtc ccctaatggt
     6061 ttcaacatct gatttcctcc ataatgagat agatattatt agcgctcttt atacctgagt
     6121 gctaattcat agttctattg tatcacttag tcagaaataa tcaagaaaaa agtctgactt
     6181 tctcaagata aaaagcctga gaccaactca gactttttaa tgtttatact caatgaaaat
     6241 caaagagcaa actaggaagc tagccgcaag ctgctcaaag cattgctttg atgttgtgga
     6301 taaagctaac gtggtttgaa gagattttcg aagagtatta aaatggcaat tcttcctctt
     6361 ccaagactaa atctgccaaa tcttggcctg cattattttc acgcatggca cgttgagcac
     6421 gactttccaa gagttggaat cctgttacaa gtacttcggt cacgtagttc atttggccat
     6481 ttttctcaaa gcgacgggta cgcaattctc catcaacgga aatgagacta cctttggttg
     6541 cgtagcttgc caaagtttct gctagtctgc cccataggac catattgaca aaatcagctt
     6601 cacgttcacc gttttggtct ttgtaacgac ggttcacagc gatagttgct cgcgctaccg
     6661 acttgtcatt gttggttttg tgcaattctg gtgtagacgt taaacgccca atcatgataa
     6721 ctttattata catattttct tcctcctact tatctattcg taggaaatca aaaaaagtta
     6781 cagaaatttg taacttttcg aggaaatttc ttatttttta tgaatcatga aacctgtcgc
     6841 ctgttgattg gccataatgg tcatatctgt aatctgaaca cggcgaggct gactggtcac
     6901 atagactact gtgtctgcaa tatcctgagc ttgcaaggct tctattcctt ggtaaacgga
     6961 cgcagctcgc tctttatcac catgaaaacg aacagttgag aaatctgttt cgacaatccc
     7021 aggctgaatg gttgtcacct tgatatccgt tgcgatggta tcaattcgca gtccatccga
     7081 aaaggtctta accgcagcct tggtagctga gtaaacagcg gcaccagcat aggcgtagat
     7141 tcctgcggtt gaccccatat tgataatatg accttgattg acttttatca ttgctggcaa
     7201 gaaacagcga gtaaccgcca tcagaccttt aacattggta tccaacatgg tcaacatatc
     7261 caactcctca tagtcttgat agggagccaa gtcaagagcc agtccggcgt tgttgaccaa
     7321 gatatcaatc ctccctatcg tttctagaat atcagagcaa acagtcttca ccatgaccat
     7381 atccgtcaca tctagtggaa aagtccagac ggtttgattt ggaaagctta ctgcaaactc
     7441 cgacttgagg atttctaatc tgtctatccg tcgtcctgtt agaacgacat cctcaccctg
     7501 ctccagataa gcacgcgcaa tcgcttcacc gattcctgag gttgctcccg taatcactac
     7561 attttttgcc atcttatttc cttctatcag atgctgacaa gttcctaggc agtccagtgt
     7621 ttcgctgggt cgaacggtgt tccgacaact tggtcttctg ataattcaag caccccacgt
     7681 ttttgcggag catttggcaa atgcaattca cgaggactac acatcatccc aaaactcttt
     7741 tcaccacgaa gttcgcctgg gaaaatgaaa ttcccttttg gcatcatggc accaggaaga
     7801 gccacaatgg ttttcaaccc aacacgcgca ttaggtgctc ctgcaacgat ttgcactatc
     7861 ttgtcacttg cgactgcaac ttggcagatg ttgaggtggt cactgtctgg atgagctacc
     7921 atctcgacaa tttcaccaac aacaaactta ggttccttat cattaacaat ttcttctgta
     7981 aaaccttccg cctgtaattc ttggttcaaa cgagcgactt gctcatctga taaaaagact
     8041 tgaccgcgct ctgcaatttc aaacaagctc gaaacctcaa aaatgttcca agccactgtt
     8101 tccccatttt ctttgaggaa aacacgggct accttgcctt tgcgttccac attcagtttg
     8161 gcatctccgc tatttttcac gatgaccata aggacatcac tgacatgttc tttgttatac
     8221 gtaaaaatca ttgtttcctt tttctcctat ttcaatcctg ctaaaaaatc gttaatttgc
     8281 tccttacttt tacggtcgcg attgacaaaa cgaccgattt ccttgtcctt ttctagaaca
     8341 acaaggctag gaattccgta aacatcccag agtttggcca aatccatata ctgatctcgg
     8401 tccattcgaa taaaggtgaa ctctggattg gtctcttcaa tctctggtaa ggcaggataa
     8461 atataacgac aatcgccaca ccagtctgcc acaaaaagga agaccttctt gcccgctttt
     8521 tccactaaag atgctaattc ttctaaactt gctggctgta tcataagact tcctcctcat
     8581 agactaggtc ttcattttca tagacaaagg tataatgacg gccatcctca aaaatgacgc
     8641 caccaaccaa gctctccaga ctgctttcgt aaacttgaac ataaagggtc gcaatttccc
     8701 ccatgtcgga aaaatggtct cgcacaatct ctgtcaactc ttcctgagtc ttcatgagct
     8761 tacggtcatc tgcaactttt ttcgtagcaa gagcaaggct tccgatacct agcagagcca
     8821 agcctgccat ccacattttt ttagctttca taccattcat tttaacacaa aaaaggcttc
     8881 aggacaaatg aggaagcagc agaaaagcaa gtaaaaagcc tcttccttta aggaaaaaga
     8941 cttcttatac taagagcaaa ctaggaagct agccgcaggc tgctcaaaac acggttttga
     9001 ggttgtagat aaggcgacgt tgacgtggtt tgaagagatt ttcaaagagt attattctta
     9061 ttgccaggca cctaagttgc caacgtagta actatcaggt gtgtaggtat tgcgaagcat
     9121 cttacctgat gaagccagat aatactactt gccattgtct ttgacccaat cattcgcaat
     9181 catggaacca gaagaactta cataatacca ttctcccttg tcataaaccc aagtactgac
     9241 tttcatggtt cctgagcaat taaaggcaaa aaaactgtcc aatatcattc gttttttaaa
     9301 agcatttgac actacatcat ctacgctgta gtacatagat acatcaaacg taaaagccaa
     9361 aatatcgaaa aatatacaac ttttaaaggc agcatttcat tttttaaagt ctaacaacca
     9421 tagaactgaa atcagagcaa ggcatcaatt tcctactctt agtacgtcta ttttgatggt
     9481 tgaagtgaag atttttttat ttaacgtaga caatttccaa cttcccaaaa gccacatctc
     9541 cacggatagt caaggttttg ctggttgggg ctacaggagc gtcagcctta gctgcaccaa
     9601 aggaggtttc tactttcaaa tctacacgcc agtgttgtgg aacatagacg gttgcattcc
     9661 cgaaggccac ttcaatattt aaagttgcaa aatcacctag catctctgca ttatcatagt
     9721 agattttagc atccccaaaa gcgacttcca cttggtcatc tacgagatct tgatcttgct
     9781 tatagaaggt cccgctacca aaagcgactt ccttatccgt gacgactgtt tttttcccat
     9841 tgtaccacca ttttttttca ttccagaact tacttgaatg cgtcagataa ccaacaccaa
     9901 gtaccaccaa gatgctagcc caaataagag aatgattggt aactggtaac aagtcataag
     9961 cgtaatttgc aatgatgagc gccagtaaac ctgtaaaaac tgccgaagtg agatgacgtc
    10021 taaggatgga ctcaatggac ttataagcaa aaaaaacaat acctagtaaa ggccatattt
    10081 taccatccaa agaaggaatt ccaaaattcc cttgcagcaa gatccaagct gctaaaacca
    10141 acaaaacaat accaaatgct ttctttttca tgttttttac ctcatgtttc ttagattttc
    10201 ttttaggagg gattggtaat gccgtgagac atgaacctcc ttgtgcgtct gataaaagga
    10261 aatggtgccc gttcctgaaa aggacttgtc cactgagtaa atctgacgga tgtttgcgat
    10321 cgttgacttg gaaactcgat taaaatagcg aggcaagata gactccaact catagagctt
    10381 gaggcgaacc tcataagctt ccttctggtt atgagcgtag atcttgctcc cttctgtttc
    10441 aaagaagaga atttctgaca ggtctagata atattcacct gtccccttgt aaaaagtcaa
    10501 cctcggagcc tttgactctt gcaagagccg ttgcaagtct gcaatttcat ctgtcaaagt
    10561 gggggtcttg atgacaattt cagtctcctc taaattgccg tcaatctcaa ttcgtaactt
    10621 catcacatct cctttctgac tctactatat caaagctaag ttaggaatac aagggcaaaa
    10681 aagcaagtgg tcaatttgaa gcagtaagtg gttgtaggac tagcttaact tacatgtaag
    10741 aataggaaga aaaggaatcc ccacaccaaa ccacaagcat agccaaccaa gacatccttg
    10801 ggataatgaa caccccctaa aaccctcacc aaccccagca aagctgaaaa gatcaagcat
    10861 actaagccaa taggtagact agcatgcaga caggccatgg agatgatagt tgccgaaaag
    10921 acatggcgac tgggcatcga ccgtcccgaa ctatccttat caagaagggg acagatatcc
    10981 caagtttcat aaggtctcgg gtgattgatt ttcttacgaa acagggacaa ggccacaaaa
    11041 cctgatgcag gaataagcac acaaacccca acttgctgac caagtcctag ttgcaggtaa
    11101 gtggtgacta gcaagatcag atagaccagg ggcatggcga ctgtcatcaa acgattgaaa
    11161 ctgcgtaata ggaataaaag aattggacga ctagttagtc tggagctgat atttcgatac
    11221 cattcttgat aatttttcat ttatgcttct catacttttc tagaacttgt tgagatgttt
    11281 tccccttggc aagccaatcc actagcttgt ccaagcgacg tatttcctgc atcagaggat
    11341 catcaatttc ctcaatacgg acactgcaaa tcttccctgt aattgcaatt cgttcaggga
    11401 cataatatgg tgcttgtcta aaaaaatctc cgtaagtaac atccctatcc agacaagcaa
    11461 gaacatcact cacttcatac cctgtcaacc aactggtcac ttggtgaact gactctgcct
    11521 ttccaccctt tcgctcaact tttgcaatca aggctaagta gacagcagca aatttcatat
    11581 tgtataattt ctgactcata cttctctctt tctatgtgta ctagtataaa taagaaaaag
    11641 aaggccgtca agccttcttt tgatttattc ttctgcttca tcttctgtaa attgactatt
    11701 gtacaagtca gcgtagaagc caccttgcgc catcagttcc tcatagttgc cttgctcgat
    11761 gatatttcca tctttcatga ccaagatcaa gtctgcattt cggatggttg acaagcggtg
    11821 ggcaatgaca aaggatgtgc gtccttccat caaacggtcc atggcttttt ggatcaattc
    11881 ctctgtccgt gtgtcaacag aagaagtcgc ctcatccaaa atcaaaagcg gtgcatcctt
    11941 aagaagggca cgagcaatag tcaatagttg tttttgtcct acagacaagg tcacggtgtc
    12001 atccaagatg gtatcatagc catctggcaa ggtcataata aagtggtgaa ttcccacagc
    12061 cttactagct tccatcattc gttcatcact aatccctatt tgattataga tgagattgtc
    12121 tcgaatagtt ccttcaaaga gccaggtatc ctgcaagacc attgaaaagg catcatgcac
    12181 ttctgaacgc gtcatagcct tggtatccac accatcaatg tgaatacttc ccttatcaat
    12241 ctcatagaat ttcatcaaaa gattgacaat ggttgtctta ccagtcccag tcggcccaac
    12301 aatggcaacc ttttgaccag catgaactgt cgcagagaag tcatagtctt gaacattgac
    12361 accgtccacc agaatttctc ctgctgacac gtcgtagaaa cgtggaatca gattgaccag
    12421 agttgattta ccagaacctg ttgacccaat aaaggccact gtttgaccag tttctgcttt
    12481 aaagctaaca tgttcaataa ctgcctccga atttgccgca tagcggaagg tcacatcctt
    12541 aaactcgacc tgacctttga agttttcatc agtcagctgc acttgaacag ggttttggat
    12601 agaagaatgc aaatctaaaa cttgattaat ccgcttagca gagaccatag tttggggaag
    12661 aacgatgaag agtgctccca tgagaaggaa gtccatgaca acctacatgg cataagacat
    12721 gaaaacaatc atgtcactaa agagaggcag acgcgctatc ggagcagcgt cgttaatcac
    12781 ataggcccca atccagtaaa tcgccacact caaaccactt gaaatcccca tcatgatagg
    12841 attcaaaata gccataagac ggttgacaaa caaatttaaa cgggtcaatt catcatttac
    12901 tgctgcaaat ttttcatttt gataatcctc tgcattgtag gtacgaacga cacgaatacc
    12961 tgttaaactc tcacgagtga tactgttcag tttatctgtc agcccctgaa tcaaggactg
    13021 ttttggaaag gctagcgtca tcaaaacggt cgtcatcagg acgttgacaa tcactgccac
    13081 aagtacggcc cagagccagt attctgaatg acctaaaatc ttcccaatag cccagatagc
    13141 cataattgga ccacacgtta ccacttgcaa gtccatagta atcaacattt gaacttgagt
    13201 aatgtcattg gtagtacgca tcaagaggct aggaattgaa aatttcttaa tctctgtctg
    13261 cgagtaatcc aaaactcggt taaaaatatc acttctcagc ctactagtat aagaagccgc
    13321 cactcgggat gcaaaaaatc caactgcaac tacggacaag aaggcaagaa agggcattcc
    13381 catcatcatg cttgccggct gccacaactc atctaaatta gttccttgac tacctagcaa
    13441 atccgtaatt ttcgagatat aggtcggcac ttccaactct agatagaccg aaaagcaagt
    13501 aaagagaatg gctagtaaaa tcatccccca ttcttttcta ctaattcttt tgactaattt
    13561 ctttattctc tcctcctatt cccttgatat ttgcctgtag ttgaccgaga actttctcaa
    13621 aaatcagtaa ttcatcttca tcaatgtctt ccatcaactg cttgtctatg cgttcaaaaa
    13681 aagccttaac ctgttgcatc tgagaacgtg ctttgtccgt cagacgaaca aacttagccc
    13741 gcttatcaac aggactcgcc tccaattcca ccaaaccatt ttgcactata cgcttaacca
    13801 gattactagc aacagacttg gtaatattga gttcctgctc gatatcttta atcaagacca
    13861 agtcttggtt tttctcgcga ttatccaaaa aatgcacaac ctgaccttgc ggcccaccca
    13921 taaattcaat gccgcaacgt ttggcttcct tttgcaccat caggtgaatt tgatgaccaa
    13981 aacgcttaaa gactaacatc ggtttatcca taatctcccc cttctaaata aaaatagttc
    14041 tctggagaat aattaaattt ctatgagaac tattttcttg attaaaaaaa tcccaagtga
    14101 ttttctcact taggatcatg ttctataggt taaattaaaa cccatctacg ttcgtataaa
    14161 tcttttggac gtcttcgtcg tcttcaagaa cgctgtaaag tttttcaaag gtttcaaggt
    14221 cttcgcctga caattccact tctgactgag gaatcatttc caattcagtc acttggaatt
    14281 cttcaatacc agactcacgg agggcaacga tagccttgtg aaggtcagtt ggcgctgtgt
    14341 aaactgtgat tgtaccttct tgtgcttcta cgtcatccac atccacatcc gcttcgagca
    14401 attgctcaaa gactgcgtcc gcatcttcac ctccaaatac aataacacct ttgttgtcaa
    14461 agaggtaaga aacagaacct gaagcgccca tgtttccgcc gtttttacca aaggctgcac
    14521 ggacattggc tgctgtacgg ttgacgttag aagtcaaagt atccacaatt agcatagagc
    14581 catttggccc aaaaccttcg taacgtcctt ctgtaaaggt ttcgtctgtg tttcctttgg
    14641 ctttatcaat cgctttatcg ataatgtgtt ttggcacttg ggcttgttta gcacggtcga
    14701 taacgaattt caaagctgag tttgattctg gatctggatc acctttttta gctgctacat
    14761 agatttctac accaaatttt gcatatactt tagagttggc tccatcttta gccgttttct
    14821 tggctacgat attggcccat ttacgtccca ttaggaatct ccttttttca cattttaatc
    14881 tttcttatta taacacaagt ttttttgatt ttcactagag gaaatggatt ttattagcaa
    14941 atcaagctag gatagcactt tacctgctaa gatggtcttg cctttctatc tttatcaaca
    15001 gacactcatc cacattcaaa aaacaaacta gaccattatc tgcaaataga aagtttcagc
    15061 caagtttgac aaagtcagct caaattactg tttgaagttt gtagatataa gcgacaaaaa
    15121 caatcatact gcaccttttg ttgacagtct actccagaca tatcatagtt caagtaaata
    15181 ctttgaaatc caacagttct tataggcgct attgtattct aagaaatcaa tagaagagtt
    15241 tctaagcaaa cctctaatac tcaataaaaa tcaaagagca aactagaaag ctagccgcag
    15301 gttgctcaaa acactgtttt gaggttgcgg atagggctga catggtttga agagattttc
    15361 gaagagtata atttacgtgt tcctaagatg gagaagttag actagtacac tggcacttct
    15421 aaaccattgc tagcaattga tttgttcata tttaatttca ttttttccat aaatgggtat
    15481 tagatataaa cagcaaaata tttccgatac gtgtcattct tgaatttcca atcatctaaa
    15541 acaagtaaag gataatcaat cccctgtata tcaaggaatt ggctaccctt tttacttttt
    15601 tacacatcct gtttgataga ctcattttaa catcacgagc atactccaat ggaaatcgct
    15661 aggcaagaga taaactttca gatattcgca gagagctcat cgcctctttt tgtcgcaaac
    15721 attcttctct cctaatcatt ttctacctta tcctctacct gaggatagag agttgttccc
    15781 caaatagaaa tcgtccgctt acgcactagt ggcaaatcgg ttttttcata aaccgtacgc
    15841 caccattccc aggcaagccc ggtacactct ctaattttga cagagagatt gcgaacattc
    15901 ccttttaaag gaatactagt ggtaaagtga gccgtcaaat cctgcccatt tctgtcccaa
    15961 gccttaggag tcaagacttc cttgccttga tgatcatagg ataattcatc ccaagtaata
    16021 taatattggg caacataggc accactatga tccagcagta aatctccgtt tctgtaagct
    16081 gtaaccttag tctcaacata gtctgtactg ttttgaaagg tcgcaactac attgtcacgt
    16141 aaaaaagaag ttgtatagga aatcggcaag cctggatgat cggctgtaaa gcgactgcct
    16201 tcttgaatca agtcctctac catatccacc ttgcctgtta caactcgggc acccgaactt
    16261 gggtcgcccc ctaaaataac cgccttcact tctgtattgt ccaaaatctg cttccactct
    16321 gtctgaggag ctactccttt tatcaaagat tcaaaagcag cctctacttc atcactctta
    16381 ctcgtggttt ccaacttgag atagacttgg cgcccataag caacactcga aatatagacc
    16441 aaaggacgct ctgcagaaat tcctctctgc cttaaatcct ctaccgttac agtatcttga
    16501 aacacatctc ctggattttt aacagcatct acgctgactg tataataaat ctgcttaaaa
    16561 ttaacaatct gaatctgctt ttcgcctgaa tggacagagt taaaatcaat atcaagagaa
    16621 ttccctatct tttcaaagtc agaaccaaac ttgaccttga gttgttccat gctgtgagcc
    16681 gtgatttttt catgctgcat tctagctggg acattattga cctgaccata atcttgatgc
    16741 cacttagcca acaaatcgtt taccgctccg cgaacacttg aattgctggg gtcttccact
    16801 tggagaaagc tatcgctact tgccaaacca ggcaaatcaa tactataagt catcggagca
    16861 cgatcgaccg caagaagagt gggattattc tctaacaagg tctcatccac tacgagaagt
    16921 gctccaggat agaggcgact gtcgttggta gctgttacag aaatatcact tgtatttgtc
    16981 gacaagctcc gcttctttct ttcgataaca acaaactcat cgggtagctg attaccctct
    17041 ttgatgaaac gattttcaat actttctccc tgatgggtca agagtttctt tttatcgtaa
    17101 ttcatagcta gtataaagtc atttactgct ttatttgcca tcttctacct cctaataagt
    17161 tcctggattg agttgcataa actcagactt gttcagcgaa atcagccgtg gttggactaa
    17221 gtaatccaaa atttcctcgt acaattcttc tgagacattg cgtcgccgtc tggctaaata
    17281 agaagtcgga atgaccgtat tatccaacat aaatacctta tctaagtcaa tcaaggttgg
    17341 tcttgtaaaa ggattacgag ctagatccgg ctcttctatc ataaagttct tgaccaaacg
    17401 tctggtcaag agagctggtt tgaaggtctg atttttaacc aactctttgt ttttagtcat
    17461 gctgttgtca atacagatat acatatgatt cttcacagcc aaatcgctac taatagtcgg
    17521 aaaaggcaaa taaagagcta caacatctcc tctcttaatc aagcaagagc accccctttt
    17581 ctcctaatgt aacatagaca ggattgacca agtcttctga ttgactcaga atttccaaag
    17641 tttgagtttg gcgcgctgtc aatttagtag catcttgtct cttcaataca aaatgcttgt
    17701 cgccaataac cttgacaata taatccttct ccaaagctga ctggtaaatc cacatcagat
    17761 gttgtctgtc ctgagaactc aagagagaag gattttcaag cctcccgata gtctgataaa
    17821 aatcaaaaac aggagctaac tcctgccaat ctgattggct agttgtcaag gctagaaaaa
    17881 gggctttgcg agctgatact tcttggttag ccttgagagt tactttcccc tccaagtttt
    17941 ttagaaatcg ggaaactcca gaaagcaaat ttttctctaa ctgcgagaaa taaaaacctt
    18001 tcgttcccag acataagtct ttcatgtcgc tttctctagc aaataagagc tcaaacattt
    18061 gatagtaaaa gaaaaatatc tggcactggg tcgcgctcat cttttcctta tcggcttctt
    18121 tttttaacca gagcaagggc gacaggtagc tggattgaga catttcctct acctcctact
    18181 cttttttaac tggagcatct gcactagctg ccacttcttt tgactggata ctttcccact
    18241 ggttaatctc ctctgagata agaccttcgc atgtcttgac aaatagggca aaagccttgg
    18301 tctttcctgc atatttctcc gtttggcatt gatagaggaa tttttctttc tccaggagtt
    18361 gcgcagtttt ttggtaagaa atccaatttt cctttgcatt atacaaattg ataatcccct
    18421 cacacagcaa gccgagactg gataaggcaa ccgaaatcaa acggtagcga tcacctggca
    18481 taggaatagc acaaaagaca gctatgagga aacctgccac gatttctgtt atttttaata
    18541 ccttatagcg cctacgatgt tgaacgcttt tctttaaaaa atgagctatc tgtacgtcta
    18601 atcgctctgt caggtacatt tcttctggcg tcatattcgt aactcctttc atttactttg
    18661 ataaccatag tataacatat ttgaatatca aagtatagta aaaactggac tataacttat
    18721 tagactccct gcgaaacaaa atatggtata gtagttctat gaattatgaa gcaagtaaac
    18781 aattaactga tacacgattt aagcgtcttg ttggtgttca gcgtaccact tttgaagaga
    18841 tgttagctgt attaaaaaca gcttatcaaa aaagtcggac aagctggtaa aatcttggct
    18901 gacagtggtt atcaagggct catgaagata tatcctcaag cacaaactcc acgtaaagcc
    18961 agcaaactca agccgctaac agctgaagat aa
//
LOCUS       DAVBEO010000045        18504 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 009
            SAMEA1678075-rid20185393.denovo.045, whole genome shotgun sequence.
ACCESSION   DAVBEO010000045 DAVBEO010000000
VERSION     DAVBEO010000045.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678075
            Sequence Read Archive: ERR226392
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18504)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18504)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980207.1
            Genome Coverage       :: 150x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:50:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 72 of 147
            Pseudo Genes (incomplete)         :: 72 of 147
            Pseudo Genes (internal stop)      :: 42 of 147
            Pseudo Genes (multiple problems)  :: 32 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18504
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678075-rid20185393.denovo.045"
                     /strain="KS 009"
                     /db_xref="taxon:1313"
     gene            16..86
                     /locus_tag="VQ543_001605"
     tRNA            16..86
                     /locus_tag="VQ543_001605"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:48..50,aa:Gly,seq:tcc)
     gene            122..195
                     /locus_tag="VQ543_001606"
     tRNA            122..195
                     /locus_tag="VQ543_001606"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:156..158,aa:Ile,seq:gat)
     gene            202..289
                     /locus_tag="VQ543_001607"
     tRNA            202..289
                     /locus_tag="VQ543_001607"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:236..238,aa:Ser,seq:gct)
     gene            complement(423..860)
                     /locus_tag="VQ543_001608"
     CDS             complement(423..860)
                     /locus_tag="VQ543_001608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HET2612300.1"
                     /translation="MEQLHFITKLLDIKDPNIKILDIINMDTHKEIIAKLDYEAPSCP
                     DCGSLMKKKEPEKFFGLIEDNLKQVHPIFQTVFKTFLKDKEKIVNALQLHYSNAKLEA
                     TNNLIKLIKCNAFGFRNFENFKKRIFIALNIKKERTKFVLSRA"
     gene            complement(1111..2046)
                     /locus_tag="VQ543_001609"
     CDS             complement(1111..2046)
                     /locus_tag="VQ543_001609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000844514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional biotin--[acetyl-CoA-carboxylase]
                     synthetase/biotin operon repressor"
                     /protein_id="HET2612301.1"
                     /translation="MKSYQAVYQILSKETDYISGEKIAEKLSLSRTAIWKAIKRLEQE
                     GIEIDSIKNRGYKLMNGDLILPEILEENLPIKVSFKPETKSTQLDAKEAIDLGHEANT
                     LYLASYQTAGRGRFQRSFYSPQGGIYMTLHLKPNLPYDKLPSYTLLVAGAVYKAIKNL
                     TLIDVDIKWVNDIYLNNHKIGGILTEAMTSVETGLVTDIIIGVGINFTIKDFPQELKE
                     KAASLFKATAPITRNELIIEIWRAFFETPAEELLYLYKKQSFILGKEVTFTLEQKDYK
                     GLAKDISENGKLLVQCDNGKEIWLNSGEISLNSWK"
     gene            complement(2043..2903)
                     /locus_tag="VQ543_001610"
     CDS             complement(2043..2903)
                     /locus_tag="VQ543_001610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000959966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HET2612302.1"
                     /translation="MLVFSEYQTGTIDLALSFYGYEECTPNYSFGPAIRDTYVLHYIT
                     KGQGKFYYKGKIVDLKEGDFFLLKPEELTFYQADSKEPWAYYWLGITGGKSPDYFALS
                     QISDQSYLIQSETCHTQTTAKLISDIVRFAQITKSSELAQLHIMGQLHELMFHLGTIA
                     PNQKKKNISSTHQLYLECKRLIDSHYPQSLTIQDLAKELSVHRSYLSSVFKEFNTLSP
                     KEYLLYVRMHRARQLLENTQESIKVIAYSVGFSDPLHFSKAYKQYFNQTPSHTRKEYS
                     QYQLVRKATL"
     gene            3011..5173
                     /locus_tag="VQ543_001611"
     CDS             3011..5173
                     /locus_tag="VQ543_001611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000538915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HET2612303.1"
                     /translation="MGVRIENNLFYVESKNLSLIIENRNGYLLLKHLGKTIKNYKGSN
                     SVYERDHAFSGNPTATNRTFSLDTQRQIFGQHGLGDFRKPTIQVQHSVTEVTDFRFVE
                     AKILKGQNGPQGLPSPHSMDDTETLVLMLEDSKAQLSLTLYYTTFNNDATITSYSKLD
                     NNSNQEVVIHKDFSFMADFPAADYEIATLQGAYAREKTVRRQQVEQGIFSISSNRGAS
                     GHAQTPALLLCEQGVTEDAGNVFAIQLMYSGNFEAFVQKNQLNEVRVAIGINPENFSW
                     KLAPEEYFETPVALVTHSDQGLTGISHESQNFVLKHIILSEFSKKERPILINNWEATY
                     FDFQREKLLELADEAKKVGIELFVLDDGWFGNRFDDNRALGDWVVNEEKLGGSLESLI
                     SAIHERGLQFGLWLEPEMISVDSDLYRQHPDWAIQVPDYEHTYSRNQLVLNLANPQVV
                     EYLKSVLDQLLSYHEIDYIKWDMNRNITKLGNGLTYLETQMQSHQYMLGLYELVSYLT
                     EKHSHILFESCSGGGGRNDLGMIRYFPQVWASDNTDAIARLPIQYGSSYFYPTISMGA
                     HVSAVPNHQMGRMTPLETRGHVAMMGNLGYELDLTNLSDEEKATIANQVNLYKELRPV
                     VQLGQQYRLINPDTASNEAAVQFNYGNQTIVTYVRVLSVVETMETTLKLKDLDEEGLY
                     KLQENGEVYSGAELMYAGLTVILSQGDFLSRQYIFRKL"
     gene            5265..6524
                     /locus_tag="VQ543_001612"
     CDS             5265..6524
                     /locus_tag="VQ543_001612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HET2612304.1"
                     /translation="MEWYKKIGLLATTGLALFGLGACSNYGKSADDTVTIEYFNQKKE
                     MTKTLEEITRDFEKENPKIKVKVVNVPNAGEVLKTRVLAGDVPDVVNIYPQSIELQEW
                     AKAGVFEDLSNKDYLKRVKNGYAEKYAVNEKVYNVPFTANAYGIYYNKDKFEELGLKV
                     PETWDEFEQLVKDIVAKGQTPFGIAGADAWTLNGYNQLAFATATGGGKEANQYLRYSQ
                     PNAIKLSDPIMKDDIKVMDILRINGSKQKNWEGAGYTDVIGAFARGDVLMTPNGSWAI
                     TAINEQKPNFKIGTFMIPGKEKGQSLTVGAGDLAWSISATTKHPKEANAFVEYMTRSE
                     VMQKYYDVDGSPTAIEGVKQAGEDSPLAGMTEYAFTDRHLVWLQQYWTSEADFHTLTM
                     NYVLTGDKQGMVNDLNAFFNPMKADVD"
     gene            6538..7404
                     /locus_tag="VQ543_001613"
     CDS             6538..7404
                     /locus_tag="VQ543_001613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000757171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HET2612305.1"
                     /translation="MKKVLQKYWAWAFVVIPLLLQAIFFYVPMFQGAFYSFTNWTGLT
                     YNYKFVGLNNFKLLFMDPKFMNAIGFTAIITIAMVVGEIALGIFIARVLNSKIKGQTF
                     FRAWFFFPAVLSGLTVALIFKQVFNYGLPAIGNALHIEFLQTSLLGTKWGAIFAAVFV
                     LLWQGVAMPIIIFLAGLQSIPTEITEAARIDGATSKQVFWNIELPYLLPSVSIVFILA
                     LKGGLTAFDQVFAMTGGGPNNATTSLGLLVYNYAFKNNQFGYANAIAVNLFFLIVVIS
                     IIQLRVSKKFEI"
     gene            7418..8251
                     /locus_tag="VQ543_001614"
     CDS             7418..8251
                     /locus_tag="VQ543_001614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HET2612306.1"
                     /translation="MKQDERKALIGKYILLILGSVLILVPLLATLFSSFKSTKDIVDN
                     FFGFPTNFTWDNFSRLLADGIGGYYWNSVVITVLSLLAVMIFIPMAAYSIARNMSKRK
                     AFTIMYTLLILGIFVPFQVIMIPITVMMSKLGLANTFGLILLYLTYAIPQTLFLYVGY
                     IKISIPESLDEAAEIDGANQFTTYFRIIFPMMKPMHATTMIINALWFWNDFMLPLLVL
                     NRDSKMWTLPLFQYNYAGQYFNDYGPSFASYVVGIISITIVYLFFQRHIIAGISNGAV
                     K"
     gene            8252..8332
                     /locus_tag="VQ543_001615"
                     /pseudo
     CDS             8252..8332
                     /locus_tag="VQ543_001615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            8470..9912
                     /gene="gtfA"
                     /locus_tag="VQ543_001616"
     CDS             8470..9912
                     /gene="gtfA"
                     /locus_tag="VQ543_001616"
                     /EC_number="2.4.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001122330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose phosphorylase"
                     /protein_id="HET2612307.1"
                     /translation="MPIQNKTMLITYSDSLGNNLKDLYDNLEEHFGDAIGGVHLLPFF
                     PSTGDRGFAPVDYDEVDSAFGDWEDVKRLGEKYYLMFDFMINHISRQSKYYKDYQEKH
                     EASEFKDLFLNWDKFWPENRPTQSDVDLIYKRKDRAPKQEIVFEDGSVEHLWNTFGEE
                     QIDLDVTKEVTMEFIRKTIQHLASNGCDLIRLDAFAYAVKKLDTNDFFVEPDIWDLLD
                     KVRDIAAEYGTEILPEIHEHYSIQFKIADHDYYVYDFTLPMVTLYTLYSSRTERLAKW
                     LKMSPMKQFTTLDTHDGIGVVDVKDILTDEEIDYASNELYKVGANVKRKYSSAEYNNL
                     DIYQINSTYYSALGDDDVKYFLARLIQAFAPGIPQVYYVGLLAGKNDLKLLEETKEGR
                     NINRHYYSNEEIAREVQRPVVKALLNLFSFRNRSEAFDLEGTTEIETPTAHSIVIKRQ
                     NKDKSVTAVAEIDLQNQTYRVIENGVEVSF"
     gene            10050..11243
                     /locus_tag="VQ543_001617"
     CDS             10050..11243
                     /locus_tag="VQ543_001617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008293041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen ligase family protein"
                     /protein_id="HET2612308.1"
                     /translation="MKSIGFIEKLKGLSSKELILLGIILSIFLPFYLFVVVLCLYIIS
                     LIFTGDMKSILQKMGEHPMLLLFLSYSTVISILAQNWMGLVASVGMFLFTIFFLHYQS
                     ILSHKFFRLILQFVLFGSVLSAAFASLEHFQIVKKFNYAFLSPNMQVWHQNRAEVTFF
                     NPNYYGIICCFCIMIAFYLFTTTKLNWLKVFCVIAGFVNLFGLNFTQNRTAFPAIIAG
                     AIIYLFTTIKNWKAFWLSIGVFAIGLSFLFSSDLGVRMGTLDSSMEERISIWDAGMAL
                     FKQNPFWGEGPLTYMHSYPRIHAPYHEHAHSLYIDTILSYGIVGTILLVLSSVAPVRL
                     MMDMSQESGKRPIIGLYLSFLTVVAVHGIFDLALFWIQSGFIFLLVMCSIPLEHRMLV
                     SDMTD"
     gene            11930..13909
                     /locus_tag="VQ543_001618"
     CDS             11930..13909
                     /locus_tag="VQ543_001618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000742236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HET2612309.1"
                     /translation="MKKNRVFATAGLVLLAAGVLAACSSSKSSDSSAPKAYGYVYTAD
                     PETLDYLISSKNSTTVVTSNGIDGLFTNDNYGNLAPAVAEDWEVSKDGLTYTYKIRKG
                     VKWFTSDGEEYAEVTAKDFVNGLKHAADKKSEAMYLAENSVKGLADYLSGTSTDFSTV
                     GVKAVDDYTLQYTLNQPEPFWNSKLTYSIFWPLNEEFETSKGSDFAKPTDPTSLLYNG
                     PFLLKGLTAKSSVEFVKNEQYWDKENVHLDTINLAYYDGSDQESLERNFTSGAYSYAR
                     LYPTSSNYSKVAEEYKDNIYYTQSGSGIAGLGVNIDRQSYNYTSKTTDSEKVATKKAL
                     LNKDFRQALNFALDRSAYSAQINGKDGAALAVRNLFVKPDFVSAGEKTFGDLVAAQLP
                     AYGDEWKGVNLADGQDGLFNADKAKAEFAKAKKALEADGVQFPIHLDVPVDQASKNYI
                     SRIQSFKQSVETVLGVENVVVDIQQMTSDEFLNITYYAANASSEDWDVSGGVSWGPDY
                     QDPSTYLDILKTTSSETTKTYLGFDNPNSPSVVQVGLKEYDKLVDEAAKETSDLNVRY
                     EKYAAAQAWLTDSSLFIPAMASSGAAPVLSRIVPFTGASAQTGSKGSDVYFKYLKLQD
                     KVVTKEEYEKAREKWLKEKAESNEKAQKELASHVK"
     gene            13976..15472
                     /locus_tag="VQ543_001619"
     CDS             13976..15472
                     /locus_tag="VQ543_001619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET2612310.1"
                     /translation="MKKYIFMRVLRSLVSIFLVTTLTYTIIYTLVPRKLIFKQDPNYN
                     KIATTADKRDNYENTVFERMGYIEYYDTKELQEKASSMDSSVTVEANATNKAIYEKYI
                     NQLGHGWTLGEFTESGQFYATREIPIFERVFHFYANLIDIDHTNKIQDPENPDLKRYL
                     RFENDPAIGWSLVGSGTKHKYLLYFNSQFPFVHQNFVNLNLGDSYPTYANTPVLQVIT
                     QGQGQTKTAQVQFPTGKKTSSVNIYSRTYKSPSQADSREVASYGKDDPYTATESNYQY
                     PSMIVSSAITGLIGLVLAYALAVPLGSAMARFKNTWIDSLSTGALTFLLALPTIALVY
                     IVRLIGSSIALPDSFPILGAGDWRSYVLPAVILGLLGAPGTAIWIRRYMIDLQSQDFV
                     RFARAKGLSEKEISNKHIFKNAMVPLVSGIPGAIIGVIGGATLTETVFAFPGMGKMLI
                     DSVKASNNSMVVGLVFIFTCISIFSRLLGDIWMTIIDPRIKLTEKGGK"
     gene            15472..16398
                     /locus_tag="VQ543_001620"
     CDS             15472..16398
                     /locus_tag="VQ543_001620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET2612311.1"
                     /translation="MSTIDKEKFQFVKRDDFASETIDAPAYSYWKSVFKQFMKKKSTV
                     VMLGILVAIILISFIYPMFSKFDFNDVSKVNDFSIRYIKPNAEHWFGTDSNGKSLFDG
                     VWFGARNSILISVIATVINLVIGVFVGGIWGISKSVDRVMMEVYNVISNIPPLLIVIV
                     LTYSIGAGFWNLIFAMSVTTWIGIAFMIRVQILRYRDLEYNLASRTLGTPTLKIVAKN
                     IMPQLVSVIVTTMTQMLPSFISYEAFLSFFGLGLPITVPSLGRLISDYSQNVTTNAYL
                     FWIPLTTLVLVSLSLFVVGQNLADASDPRTHR"
     gene            16407..17474
                     /locus_tag="VQ543_001621"
     CDS             16407..17474
                     /locus_tag="VQ543_001621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2612312.1"
                     /translation="MTKEKNVILTARDIVVEFDVRDKVLTAIRGVSLELVEGEVLALV
                     GESGSGKSVLTKTFTGMLEENGRIAQGSIDYRGQDLTALSSHKDWEQIRGAKIATIFQ
                     DPMTSLDPIKTIGSQITEVIVKHQGKTAKEAKELAIDYMNKVGIPDADRRFNEYPFQY
                     SGGMRQRIVIAIALACRPDVLICDEPTTALDVTIQAQIIDLLKSLQNEYHFTTIFITH
                     DLGVVASIADKVAVMYAGEIVEYGTVEEVFYDPRHPYTWSLLSSLPQLADDKGDLYSI
                     PGTPPSLYTDLKGDAFALRSDYAMQIDFEQKAPQFSVSETHWAKTWLLHEDAPKVEKP
                     AVIANLHDKIREKMGFAHLAD"
     gene            17485..18411
                     /locus_tag="VQ543_001622"
     CDS             17485..18411
                     /locus_tag="VQ543_001622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001291287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2612313.1"
                     /translation="MSEKLVEIKDLEISFGEGSKKFVAVKNANFFINKGETFSLVGES
                     GSGKTTIGRAIIGLNDTSNGDIIFDGQKINGKKSREQAAELIRRIQMIFQDPAASLNE
                     RATVDYIISEGLYNHRLFKDEEERKEKVQNIIREVGLLAEHLTRYPHEFSGGQRQRIG
                     IARALVMQPDFVIADEPISALDVSVRAQVLNLLKKFQKELGLTYLFIAHDLSVVRFIS
                     DRIAVIYKGVIVEVAETEELFNNPIHPYTQALLSAVPIPDPILERKKVLKVYDPSQHD
                     YETDKPSMVEIRPGHYVWANQAELARYQKGLN"
BASE COUNT         5423 a         3292 c         3873 g         5916 t
ORIGIN      
        1 attgatagta tttatgcggg tgtagtttag tggtaaaact acagccttcc aagctgttgt
       61 cgcgagttcg attctcgtca cccgctttga actttgttca aattaccaag ttttttaact
      121 tgggcgcgta gctcaggtgg ttagagcgca cgcctgataa gcgtgaggtc ggtggttcga
      181 gtccactcgt gcccattaat tggagaatta ctcaagaggc tgaagaggac ggtttgctaa
      241 atcgttaggt cgggtaactg gcgcaagggt tcgaatccct tattctccgt tttaatgaga
      301 gtttgtaact ctctttttta tttttagaga caataaagct tcagatccgt aaaacttaat
      361 tgaattacta atctgaagtt atttttatgg ctctttgtca actgtagtgg gttgaagaaa
      421 agctaagctc gagaaaggac aaatttcgtc ctttcttttt tgatgttcaa agcgataaaa
      481 atccgttttt taaagttttc aaagtttcga aaaccaaagg cattgcactt gataagtttg
      541 atgagattat tggtcgcttc cagtttggcg ttagaatagt gtagttgaag ggcgttgaca
      601 atcttttctt tatctttgag gaaggtttta aagacagtct gaaaaatagg atgaacctgc
      661 ttaagattgt cctcaataag tccgaaaaat ttctctggtt cctttttctt cattagactt
      721 ccacaatcag ggcaagatgg agcctcataa tccagcttag cgataatttc tttgtgggta
      781 tccatattga tgatatctag aatcttgatg tttgggtctt taatgtctag taattttgtg
      841 ataaaatgta attgttccat atgattcttt ctaatgagtt gttttgtcgc ttttcattat
      901 aggtcatatg ggactttttt tctacacaaa ataggctcca taatatccat agggaattta
      961 cccactacaa atattataga gcccgtttta atgagagttt gtaactctct tttttgtttt
     1021 tagagacaat aaaacttcag atccgtaaaa cttaattgaa ttactaatct gaagttattt
     1081 ttatatcgtt tatattataa ttgtgttatt ttacttccaa ctattgagag aaatttcgcc
     1141 actatttagc cagatttctt ttccgttatc acattgaact aaaagttttc cattttctga
     1201 gatgtcttta gcaagtccct tgtagtcttt ttgctctagt gtgaaagtga cttcttttcc
     1261 tagaatgaat gactgttttt tgtataggta taatagctct tctgctggtg tttcgaagaa
     1321 agcacgccag atttctatga tcaattcatt ccttgttata ggagctgtag ctttaaataa
     1381 gctggcagct ttttctttta attcctgagg gaagtcttta atagtgaaat tgatacctac
     1441 tccaataatg atatctgtga ctaagccagt ttctacagag gtcattgctt cagtaaggat
     1501 tcctccaatt ttatgattgt ttagatagat atcattgacc cattttatgt cgacatctat
     1561 taaagttagg ttcttaatgg ctttgtagac agctccagct acaagtagtg tgtaggatgg
     1621 taatttgtca taggggagat ttggtttaag atggagtgtc atataaatac caccttgtgg
     1681 tgagtagaag gaacgttgaa aacggcctcg gcctgctgtt tgataggaag ctagatagag
     1741 ggtatttgct tcatggccta aatcaattgc ttcttttgca tctagttgtg ttgattttgt
     1801 ttcgggttta aagctgactt taattggaag attttcttct agaatctctg gaagaataag
     1861 gtcaccattc atcagtttat atcctctatt tttgatacta tcaatttcaa tgccttcttg
     1921 ttctagtcgc ttgatggctt tccaaattgc tgttcggctt agggatagtt tttctgcgat
     1981 tttttctccg ctgatatagt cggtttcttt agataggatt tggtagacag cttggtagga
     2041 tttcataatg ttgcctttct cactagttgg tattgagagt attcttttct tgtatgactt
     2101 ggagtctgat taaagtattg tttataagct ttcgaaaaat ggagtggatc tgaaaaacct
     2161 accgagtatg caattacctt gatggactct tgggtatttt cgagaagttg tctagctcgg
     2221 tgcattcgaa cgtagagtag gtattctttg ggtgataagg tattaaattc tttgaatacg
     2281 cttgataagt agcttctgtg aacggatagt tcttttgcta aatcttgaat tgtaagtgat
     2341 tgaggatagt ggctatcaat taatcgtttg cattcaagat agagttggtg ggttgatgaa
     2401 atattctttt ttttctgatt gggagcaata gttcccagat gaaacatcag ttcatgaagt
     2461 tgtcccatga tatggagttg agctaattca cttgattttg taatctgagc gaagcggaca
     2521 atgtctgaga tgagttttgc agtagtctgg gtatgacaag tttcagattg gatgagatag
     2581 gattgatcag aaatttgaga aagagcaaaa taatcagggg atttccctcc agtgattcct
     2641 aaccagtagt aggcccaagg ttctttacta tctgcttgat aaaaggttag ttcctctggt
     2701 tttaatagaa agaaatctcc ttcttttaaa tcaacaattt tacccttgta ataaaatttt
     2761 ccttgtcctt tagtaatgta atgtagaacg tatgtatcac gaatggctgg accaaaagag
     2821 taattaggtg tgcattcctc atatccataa aagcttaggg caaggtcgat tgttccagtc
     2881 tggtattctg aaaaaactaa catgtgctac ctcctaccta acattttacc atattcttga
     2941 gacatttttc tattttggaa agcgatttca ggtgataaaa tataatcaat aaagtgatga
     3001 ggtgaagtaa atgggagtta ggatagagaa taatctattt tatgttgaga gtaaaaatct
     3061 aagtttgatt attgaaaatc gaaatggcta cttacttttg aaacatttag gaaagactat
     3121 taagaactat aaaggttcca atagtgttta tgaacgagac catgcctttt caggaaatcc
     3181 aacggctact aatcgaacct ttagtttaga tactcagcga cagatttttg gacaacatgg
     3241 cttaggagat tttaggaaac caactataca ggttcagcat agtgtaactg aagtaacaga
     3301 ctttcgattt gtagaagcaa agattttaaa aggtcagaat ggtccacagg gcttaccttc
     3361 tccacatagc atggacgata cagagactct tgtcttaatg ttagaagatt ctaaggctca
     3421 acttagtctg actttgtatt atactacttt taataatgat gcgactatta ctagctacag
     3481 taaattagat aataatagta atcaggaagt tgtcatccat aaagattttt cttttatggc
     3541 tgattttcca gctgcagatt acgaaatagc aactctgcag ggtgcttatg ctcgtgaaaa
     3601 gactgttaga cgtcaacagg tagaacaagg aatcttttcg attagttcaa accgaggtgc
     3661 ttctggtcat gctcaaacac cagctcttct actatgcgaa caaggagtca cagaggatgc
     3721 tgggaatgtg tttgctattc aactaatgta tagtggcaac tttgaagctt ttgttcaaaa
     3781 aaatcaattg aatgaagttc gggtggctat tggcattaat ccagaaaact tttcttggaa
     3841 gttagcccct gaggaatact ttgaaacacc ggtagcttta gtgactcatt cagatcaggg
     3901 attaactggt attagtcatg aaagtcagaa ttttgtactg aagcacatta ttctaagtga
     3961 attttctaaa aaagaacgtc caattctaat caataactgg gaagctactt actttgactt
     4021 tcagagagaa aaactgttag agttagcaga tgaagctaag aaagttggca ttgaactttt
     4081 tgtattagat gatggttggt ttggcaatcg ttttgatgat aatcgtgctt taggtgattg
     4141 ggttgttaat gaggaaaaac tgggtggaag tctagaaagt ctgatttcag ctatccatga
     4201 aagaggtttg cagtttggac tttggttaga acccgaaatg atttctgtag atagtgattt
     4261 gtatcgtcaa caccctgact gggctattca ggttcctgac tatgagcata cttattctcg
     4321 gaatcaatta gtacttaatc ttgccaatcc tcaggtagta gaatacttga aaagtgtctt
     4381 agatcaactc ctatcttatc atgagattga ttacattaaa tgggatatga accgcaatat
     4441 cactaagcta gggaatggat taacttatct agagacacag atgcaatctc atcagtacat
     4501 gctggggctt tatgaactcg tttcttatct gacagagaag cacagccata ttctctttga
     4561 gtcctgctct ggtggtggtg gacgaaatga tcttggtatg atacgctatt tcccacaagt
     4621 ctgggctagt gataatactg atgccattgc acgtttacca attcaatacg gttcatccta
     4681 tttctatcca accatttcta tgggggctca tgtgtcagca gtaccgaatc atcagatggg
     4741 acgaatgaca ccattagaaa cacgtggcca tgtagcaatg atgggaaatt tgggctatga
     4801 gcttgatttg acaaatttat cagatgaaga gaaagctacg attgctaatc aggtgaactt
     4861 gtataaagaa ttacgaccag tagttcagtt aggacagcag tatagactaa ttaatcctga
     4921 tactgcatcc aatgaagcag ctgtacaatt taattacgga aatcaaacga ttgtaaccta
     4981 cgttcgcgtt ttatctgttg tagagaccat ggaaacaact ttaaaattaa aagatttgga
     5041 tgaagaggga ctatataaat tacaggaaaa tggcgaagtt tactcaggtg cagaactaat
     5101 gtatgcgggc ttaactgtta tcttatccca aggagatttt ttgagtagac agtatatttt
     5161 tagaaaacta tgatatgtac tgaccccaaa agttagattt attctatcta acttttgaag
     5221 tgcagtttga taagggtgta taaatttata aaggaggctt tctaatggaa tggtataaaa
     5281 aaatcggact tcttgcaact acaggtttag ctttgtttgg gctcggtgct tgctccaact
     5341 atggtaaatc tgcggatgac acagtgacca tcgagtattt caaccagaaa aaagaaatga
     5401 ccaaaacctt ggaagaaatc actcgtgatt ttgagaagga aaaccctaag ataaaggtca
     5461 aagtcgtcaa tgtaccaaat gctggtgaag tattgaagac acgcgttctc gcaggagatg
     5521 tgcctgatgt ggtcaatatt tacccacagt ccatcgaact gcaagaatgg gcaaaagcag
     5581 gtgtctttga agatttgagt aacaaagact acctgaaacg cgtgaaaaat ggctacgctg
     5641 aaaaatatgc tgtaaacgaa aaagtttaca acgttccttt tacagctaat gcttatggaa
     5701 tttactacaa caaagataaa ttcgaagaac tgggcttgaa ggttcctgaa acctgggatg
     5761 aatttgaaca gttagtcaaa gatatcgttg ctaaaggaca aacaccattt ggaattgcag
     5821 gtgcagatgc ttggacactc aatggttaca atcaattagc ctttgcgaca gcaacaggtg
     5881 gaggaaaaga agcaaatcaa taccttcgtt attctcaacc aaatgctatt aaattgtcgg
     5941 atccgattat gaaagatgat atcaaggtca tggacatcct tcgcattaat ggctctaagc
     6001 aaaagaactg ggaaggtgct ggctataccg atgttatcgg agccttcgca cgtggggatg
     6061 tcctcatgac accaaatggg tcttgggcga tcacagcgat taatgaacaa aaaccgaact
     6121 ttaagattgg aaccttcatg attccaggaa aagaaaaagg acaaagctta accgttggtg
     6181 cgggagactt ggcatggtct atctcagcca ccaccaaaca tccaaaagaa gccaatgcct
     6241 ttgtggaata tatgacccgt tcagaagtca tgcaaaaata ctacgatgtg gacggatctc
     6301 caacagcgat cgaaggggtc aaacaagcag gagaagattc accgcttgct ggtatgaccg
     6361 aatatgcctt tacggatcgt cacttggtct ggttgcaaca atactggacc agtgaagcag
     6421 acttccatac cttgaccatg aactatgtct tgaccggtga taaacaaggc atggtcaatg
     6481 atttgaatgc cttctttaac ccgatgaaag cggatgtgga ttaggagtag agagactatg
     6541 aaaaaagtat tacaaaaata ttgggcatgg gcttttgtgg tcatccccct cttgttacaa
     6601 gcaattttct tctatgtgcc gatgtttcaa ggagcctttt acagttttac caactggaca
     6661 ggattgactt acaactacaa atttgtcggc ttaaacaact ttaagctcct cttcatggat
     6721 ccaaaattca tgaatgcgat tggctttacc gcaatcatta cgattgccat ggtggttggt
     6781 gagattgcac tcgggatctt cattgcgcgt gtcttgaact ctaaaatcaa aggccaaacc
     6841 ttcttccgtg cttggttctt cttcccagct gttttatctg gtttgacagt ggctttgatc
     6901 ttcaagcaag tcttcaacta cggtcttcca gcgattggga atgcccttca tattgaattt
     6961 ctccaaacca gtcttttagg gactaagtgg ggagcaatct ttgcggctgt ctttgtcctt
     7021 ctttggcaag gggtggctat gcccatcatc atcttcctag ctggtttgca atctattcca
     7081 actgagatta cagaggcagc aaggattgat ggtgcgacta gcaagcaagt tttctggaac
     7141 attgaattgc cttacttgct accaagtgtc tctatagtct ttatcctagc cctaaaaggt
     7201 gggctgactg cctttgacca agtctttgcc atgaccggtg gtggtccaaa caatgccaca
     7261 acctcacttg ggctcttggt ttataactat gcctttaaaa acaaccaatt cggttatgcc
     7321 aatgccattg ccgtaaactt gttcttctta attgtagtga tttcgatcat ccaattgaga
     7381 gtatctaaga aatttgaaat ttaagaggag aagcatgatg aaacaagatg aaagaaaagc
     7441 cctgattggc aaatacattc tattgattct aggatcggtt ctgattttag tgccgctcct
     7501 tgctaccctc tttagttcct tcaaatccac taaggatatt gtagataatt tctttggctt
     7561 tccaaccaac ttcacatggg acaactttag ccgtctctta gctgatggga ttggaggcta
     7621 ttattggaac tctgtcgtca tcactgtctt gtctttactt gcagtaatga tctttatccc
     7681 tatggcagcc tactccatcg ctcgcaatat gagtaaaaga aaagccttta ccatcatgta
     7741 taccctctta atcctcggaa tcttcgtacc tttccaagtc atcatgattc cgattacggt
     7801 tatgatgagt aaactcggtt tggctaatac ctttggtttg atcttgctct acttgaccta
     7861 tgcgattcca cagaccctct ttctctatgt tggctatatc aaaatctcga ttccagaaag
     7921 tctggatgaa gcagcagaga tcgatggggc taatcaattt acaacctatt tccgcatcat
     7981 cttcccaatg atgaaaccga tgcatgcgac aaccatgatc atcaatgccc tttggttctg
     8041 gaatgacttc atgttgccac tccttgtctt gaaccgggat tccaaaatgt ggactctgcc
     8101 tttgttccaa tacaactacg caggccaata tttcaacgac tacggaccaa gctttgcctc
     8161 ttacgtggtc ggcattatca gtatcaccat tgtctatctc ttcttccaac gccatatcat
     8221 cgcaggaata agcaacgggg cagtgaagta atactcaatg aaaatcaaag agcaaactag
     8281 gaagctagcc gcaggttgct caaaacactg ttttgaggtt gtggatgaaa ctgacgaagt
     8341 cagtaaccat atctacggta aggcgacact gacgtggttt gaagagattt tcgaagagta
     8401 taacatgaat ttgatttacg aagccagatc atatgagact tggcttcaat tagaaaaagg
     8461 agagtaatga tgccaattca aaataaaacc atgttgatta cctattctga tagccttgga
     8521 aataatctta aagacttata tgataatttg gaagagcatt ttggagatgc tattggagga
     8581 gttcaccttt taccattttt cccatcaaca ggtgatcgtg gatttgcgcc agttgactac
     8641 gacgaagtgg actcagcttt tggtgattgg gaggatgtta agcgtttagg tgagaaatat
     8701 tatcttatgt ttgattttat gattaatcat atttctcgtc aatccaagta ttataaggac
     8761 tatcaagaaa aacatgaagc cagtgaattt aaagatctct ttttaaactg ggataagttt
     8821 tggccagaaa accgtccgac acagtctgat gtagatttaa tttacaagcg taaggatcgt
     8881 gcaccaaagc aagagattgt gtttgaagat ggttcagtgg aacatttgtg gaataccttt
     8941 ggtgaggagc agattgatct tgatgtgacc aaagaagtaa ctatggaatt tatccgtaag
     9001 accattcagc acttggcaag taatgggtgt gatttgattc gtctagatgc ctttgcttat
     9061 gcagtgaaga aattggatac taatgatttc tttgtggaac cagatatttg ggatttattg
     9121 gacaaagttc gagatatcgc tgctgagtat gggacagaga ttttacctga gattcatgaa
     9181 cactattcga ttcagtttaa aatagcagac catgattact atgtttatga ttttactctt
     9241 ccaatggtga cactttatac tctttacagt tccagaacag agcgtttggc taagtggttg
     9301 aagatgagcc cgatgaagca atttacgacg ctagataccc atgatgggat tggagtagta
     9361 gatgtcaagg atatcctgac cgatgaggag attgactatg cttcaaatga actctataag
     9421 gttggagcca atgtcaaacg taagtactct agtgccgagt ataacaactt agatatctac
     9481 caaatcaatt caacctacta ttcagcgctt ggagatgatg atgtcaagta ttttctcgct
     9541 cgtctaattc aagcttttgc cccaggtatt cctcaggttt actatgtggg tctattagca
     9601 ggcaagaatg acttgaaatt attagaagaa actaaagaag gtcgaaatat taatcgtcat
     9661 tactatagca acgaggaaat agcaagagaa gtgcaacgac ctgttgtgaa ggcccttctc
     9721 aatctatttt ctttccgtaa ccgttcagaa gcctttgatc tagaagggac tactgagata
     9781 gagacaccaa cagctcacag cattgtaatc aaacgtcaaa ataaagataa gtccgtaaca
     9841 gcagtagcag aaattgattt gcaaaatcag acttatcggg taattgagaa tggagttgaa
     9901 gtatcatttt gaagccttga tatggtggat aaaatagggt ttttattttg gaaaacgttt
     9961 cctttgtttt caaattgcta aaaaagtggt acaatatagg atagcttact attatctgaa
    10021 tcagctgatt tggagagaaa ggattcattt tgaaatcaat aggctttatt gaaaagctga
    10081 aggggttgtc tagtaaagag ctgattttat tgggaattat cctaagtatc tttttaccct
    10141 tttatctttt tgtagttgta ctctgtttat atattatcag tttgattttt acaggagaca
    10201 tgaaaagtat tcttcagaaa atgggggagc atccgatgct gcttcttttt cttagctata
    10261 gtactgttat atccattctt gcacaaaatt ggatgggtct tgtggcttca gtaggaatgt
    10321 ttctatttac tattttcttt ttgcactatc agtcgatttt atcccataaa ttctttcgat
    10381 tgattttgca gttcgtcttg tttggtagtg tcttgtcagc tgcttttgcc agtttagaac
    10441 atttccaaat tgtgaagaaa tttaactatg cttttctttc acccaatatg caggtgtggc
    10501 atcagaaccg ggcagaagtg accttcttta atcctaatta ttatggaatt atttgttgtt
    10561 tctgtattat gattgctttc tatctgttta caacgaccaa gttgaattgg ttgaaagtat
    10621 tctgtgtgat tgcaggcttt gttaatctct ttggtttgaa ctttactcaa aatcgaactg
    10681 cctttcctgc tattatcgct ggagcaatta tctatctctt tacgactatt aaaaactgga
    10741 aggccttttg gcttagtatt ggggtcttcg cgattggttt gagtttcctc ttttctagtg
    10801 atttgggagt tcgaatgggt actttagact cttctatgga agaacgcatt tctatctggg
    10861 atgctgggat ggccttgttt aagcaaaatc ctttttgggg tgaagggcca ttgacctata
    10921 tgcactctta tcctcggata catgctcctt atcatgaaca tgcccacagt ctttatattg
    10981 atacgattct gagttacgga attgtgggta ccattttatt agttttgtct tctgttgctc
    11041 ctgttcgctt gatgatggat atgagtcagg agtcggggaa acgtccgatt atcggccttt
    11101 atctatcttt ccttacagtg gttgctgtgc acggaatttt tgacttggct ctcttctgga
    11161 ttcagtcagg ctttattttc ttgctagtta tgtgcagtat tccattggag catcgaatgt
    11221 tggtatcgga catgacggat taagttttat aagtttgaaa tcttctacct tgggtaggag
    11281 atttttttat acgatgggca tgtcgtgcat ctgaggtgta agtcctctgt agggatccac
    11341 taccggtgaa tacaatagcg ctccccaagc ctgactatcg tgaggtagcg gattaaaatg
    11401 gtctggggat agatcgtttt aagtctgacg caggaaataa gaattgtcag agaaagcaat
    11461 agtgaaatcg taggctatga atagaaacgt gatagcgagg agcatatagt ggataaggta
    11521 gcgagaaatt ttaaagtata aaagatagtc ttaatctata tatgtaaatc acaaaagtaa
    11581 ttgaattcgg aataaggttg gtgtgaaaag acatagtaaa ctgaatcttg aatactagaa
    11641 tgatacttct acaatattgt tataatttaa tttgaattcc aaaatcacat tgttccgtcc
    11701 gtatttcatt ttactgtatg tcttcctaaa ctccaaagtt tctgcgtcaa atttcctatt
    11761 ttcactgtag tctttgacac ttcgaacgac aatttgaatc atatattcaa aaaaaaatga
    11821 aaaatttgtg ccaacaagcc taaatattct gaaaatttgt ttgattttta atggataatg
    11881 tgatataatg gttgtcaatc tataattcac ataaacagag gagtagaaaa tgaaaaaaaa
    11941 tcgtgtattt gctacagcag gtcttgtttt attagcagca ggtgtacttg cagcatgcag
    12001 ttcttcaaaa tcatctgatt catcagcccc taaagcttat ggctatgttt atacagcaga
    12061 cccagaaacc ttggactacc tgatttcaag taaaaatagt acaacagtag tgacttcaaa
    12121 tgggattgat ggtttattca ctaacgataa ttacggtaat cttgctcctg cagttgcaga
    12181 ggattgggaa gtctctaagg atggtttgac ctacacttat aagattcgta aaggggttaa
    12241 atggtttacc tctgatggag aagaatatgc agaggtgacg gctaaagatt tcgtgaacgg
    12301 tttaaaacac gcagcagata aaaaatcaga agctatgtat ttagctgaaa attcggttaa
    12361 aggcttggca gattatctat caggaacttc aacagatttt tcaacagttg gtgtcaaggc
    12421 ggttgatgat tatacgttac aatacacttt gaaccagcct gaaccgttct ggaactctaa
    12481 gttgacctat tctattttct ggcctctgaa tgaagaattc gaaacatcaa aaggaagcga
    12541 ttttgctaaa ccaacagatc cgacatcctt gctttataat ggtccattct tgttgaaagg
    12601 gttgactgca aaatcttctg tagagtttgt aaaaaatgag caatattggg ataaagaaaa
    12661 tgtccaccta gatactatca atctagctta ctatgatgga tcagatcagg agtcgctaga
    12721 gcgtaacttc actagtggag cttatagtta tgcccgtctt taccctacca gctccaacta
    12781 ttctaaggtt gcagaagaat acaaggacaa tatctattac acacaatcag gctctgggat
    12841 tgctggtctg ggtgtgaata ttgatcgcca aagttacaac tatacttcta aaactacaga
    12901 ttcagagaaa gtagctacta agaaggcatt gcttaacaaa gatttccgtc aagccttgaa
    12961 ttttgctctt gatcgctcag cttactcagc tcaaatcaat ggtaaagatg gagcagcttt
    13021 agcagttcgt aatttatttg taaaaccaga ctttgtttca gctggtgaga agacctttgg
    13081 tgatttagtc gctgctcaac ttcctgctta tggtgatgag tggaaaggtg tgaatttagc
    13141 tgatgggcag gatggtttat tcaatgctga caaggccaag gcagagtttg cgaaagctaa
    13201 gaaagcttta gaagcagacg gcgttcagtt tcctattcat ctggacgttc cagtagacca
    13261 agcatcaaaa aactacatat ctcgtattca gtcctttaaa caatctgtag aaacagttct
    13321 tggtgttgaa aatgtcgttg ttgatattca acaaatgaca agtgatgaat tccttaatat
    13381 tacttactat gctgccaatg cttcatctga ggattgggat gtatcgggag gagtttcatg
    13441 ggggccagac tatcaagacc catctactta cctggatatt ttaaaaacaa ctagcagtga
    13501 aactacaaaa acatatttag gatttgataa tccaaatagc ccttcagtag ttcaagttgg
    13561 tttgaaagaa tacgataaat tagttgatga agctgccaaa gagacaagcg acttgaatgt
    13621 ccgttatgaa aaatatgcag cggctcaagc atggttgaca gatagttcac tctttattcc
    13681 tgctatggct tcttctggtg cagcaccagt gctttcacga attgttccat ttactggagc
    13741 ttctgcgcaa acaggctcta aggggtcaga tgtttacttc aaatatttga aattacaaga
    13801 taaagtggtg actaaggaag agtatgaaaa agctcgtgaa aaatggttga aagaaaaagc
    13861 tgaatcaaat gagaaagctc aaaaagaatt ggcaagtcat gtgaagtaaa taatttctaa
    13921 tagaactttc tctccatgag gagaaggttc ttttgggatt tttaaaggaa ataatatgaa
    13981 aaaatatatt tttatgcgtg ttttgcggtc attggtttcg attttcttag taacgacttt
    14041 gacctacacg attatctata ccttggttcc tcgaaaattg attttcaagc aggatcctaa
    14101 ctataataaa attgcaacaa cggctgataa acgtgataac tatgaaaata ctgtgtttga
    14161 gcgtatgggc tacattgagt attacgatac taaagagttg caagaaaagg caagtagcat
    14221 ggattcttct gtaacagtag aagcaaatgc gaccaataaa gctatttatg aaaagtacat
    14281 caatcaatta ggtcatggtt ggactttggg agaatttact gaaagtggtc aattctatgc
    14341 tactcgtgaa attccaattt ttgaacgtgt ttttcacttc tatgctaact tgattgacat
    14401 tgaccataca aataaaatcc aagaccctga aaatccagac ttgaaacgct accttcgttt
    14461 tgaaaatgat ccagctatcg gatggtcatt ggtcggttca ggaactaaac ataaatatct
    14521 cttgtacttt aacagtcagt tcccatttgt tcatcaaaac tttgtgaact tgaatttagg
    14581 tgactcttac ccaacctatg ctaatacacc agttcttcag gttattactc aaggtcaagg
    14641 acaaaccaaa actgcccaag ttcagttccc aacaggtaag aaaacgtctt ctgtaaatat
    14701 ttactcaaga acctacaagt cacctagtca ggctgactct cgtgaagtag ctagctatgg
    14761 gaaagatgat ccttatacag cgactgaaag taattaccaa tatccatcta tgattgtcag
    14821 ctctgctatt actggtttga ttggtttggt tcttgcctat gctcttgccg tgccacttgg
    14881 ttcagccatg gctcgtttca agaacacttg gattgatagc ctctcaacag gggctttgac
    14941 cttcttgctt gctcttccaa cgattgcctt ggtttacatc gttcgattga ttggatcatc
    15001 tattgccctt ccagattcat tccctatctt gggagctgga gattggcgtt cttacgtttt
    15061 accagcagtc atccttggtt tgttgggtgc tcctggtaca gccatttgga ttcgtcgtta
    15121 catgattgac ttgcaatctc aagactttgt tcgtttcgct cgtgcaaaag gtttgtctga
    15181 aaaagaaatt tcaaacaaac acatctttaa aaatgccatg gttccgctgg tttcaggaat
    15241 tcctggtgcc atcattgggg ttatcggtgg tgcaaccctt actgaaacag tcttcgcctt
    15301 cccaggtatg ggtaaaatgt tgattgactc tgtaaaagca tctaataact ctatggtcgt
    15361 tggtcttgtc ttcatcttta catgtatttc tatcttctca cgtcttttgg gagatatttg
    15421 gatgactatt attgacccac gtattaaatt gactgagaaa ggaggcaaat aatgtctaca
    15481 atcgataaag aaaaatttca gtttgtaaaa cgtgacgatt ttgcctctga aactattgat
    15541 gcgccagcat attcttactg gaaatcagtg tttaaacaat ttatgaagaa aaaatcaact
    15601 gtagtcatgt tgggaatctt ggtagccatc attttgataa gtttcatcta cccaatgttt
    15661 tctaagtttg atttcaatga tgtcagcaag gtaaacgact ttagtattcg ttatatcaag
    15721 ccaaatgcgg agcattggtt cggtactgac agtaacggta aatcgctctt tgacggtgtc
    15781 tggttcggag ctcgtaactc catcctcatt tctgtgattg cgacagtgat taacttggtt
    15841 atcggtgttt ttgtcggtgg tatttggggt atttcaaaat cagttgaccg tgtcatgatg
    15901 gaagtttaca acgtcatctc aaacatccca cctcttttga ttgttattgt cttgacttac
    15961 tcaatcggag ctggattctg gaatctgatt tttgccatga gcgtaacaac atggattggt
    16021 atcgccttca tgatccgtgt gcaaatcttg cgctatcgtg acttggaata caacttggca
    16081 tcacgtactt tgggaacacc aaccttgaag attgttgcca aaaatatcat gcctcaattg
    16141 gtatctgtta ttgtgacaac catgactcaa atgcttccaa gctttatctc atacgaagcc
    16201 ttcttgtctt tcttcggtct tggattaccg attacagtgc caagtttggg tcgtttgatt
    16261 tcggattatt cacaaaacgt aacaaccaat gcttacttgt tctggattcc attgacaacc
    16321 cttgtcttgg tatccttgtc ccttttcgta gttggtcaaa acttagcgga tgctagtgat
    16381 ccacgtacac atagatagga gtagaaatga caaaagaaaa aaatgtaatt ttgactgctc
    16441 gcgatattgt cgtggaattt gacgttcgtg acaaagtatt gacagccatt cgcggcgttt
    16501 cccttgaact cgttgaagga gaagtattag ccttggtagg tgagtcagga tcaggtaaat
    16561 ctgttttgac aaagaccttc acaggtatgc tcgaagaaaa tggtcgcatt gcccaaggta
    16621 gtattgacta ccgtggtcag gatttgacag ctttatcttc tcacaaggat tgggaacaaa
    16681 ttcgtggtgc taagattgcg actatcttcc aggacccaat gactagtttg gaccccatta
    16741 aaacaattgg tagtcagatt acagaagtta ttgtaaaaca ccaaggaaaa acagctaaag
    16801 aagcgaaaga attggccatt gactacatga ataaggttgg cattccagac gcagatagac
    16861 gttttaatga atacccattc caatattctg gaggaatgcg tcaacgtatc gttattgcta
    16921 ttgcccttgc ctgccgacct gatgtcttga tctgtgatga gccaacaact gccttggatg
    16981 taactattca agctcagatt attgatttgc taaaatcttt acaaaacgag tatcatttca
    17041 caacaatctt tattacccac gaccttggtg tggtggcaag tattgcggat aaggtagcgg
    17101 ttatgtatgc aggagaaatc gttgagtatg gaacggttga ggaagtcttc tatgaccctc
    17161 gccatccata tacatggagt ctcttgtcta gcttgcctca gcttgctgat gataaagggg
    17221 atctttactc aatcccagga acacctccgt cactttatac tgacctgaaa ggggatgctt
    17281 ttgccttgcg ttctgactac gcaatgcaga ttgacttcga acaaaaagct cctcaattct
    17341 cagtatcaga gacacattgg gctaaaactt ggcttcttca tgaggatgct ccaaaagtag
    17401 aaaaaccagc tgtgattgca aatctccatg ataagattcg tgaaaaaatg ggatttgccc
    17461 atctggctga ctaggaggaa ggaaatgtct gaaaaattag tagaaatcaa agatttagaa
    17521 atttccttcg gtgaaggaag taagaagttt gtcgcggtta aaaatgctaa cttctttatc
    17581 aacaagggag aaactttctc gcttgtaggt gagtccggta gtgggaaaac aactattggt
    17641 cgtgctatca tcggtctaaa tgatacaagt aatggagata tcatttttga tggtcaaaag
    17701 attaatggta agaaatcgcg tgaacaagct gcggaattga ttcgtcgaat ccagatgatt
    17761 ttccaagacc ctgctgcaag tttgaatgaa cgtgcgactg ttgattatat tatttctgaa
    17821 ggtctttaca atcaccgttt atttaaggat gaagaagaac gtaaagagaa agttcaaaat
    17881 attatccgtg aagtaggtct tcttgctgag cacttgactc gttaccctca tgaattctca
    17941 ggcggtcaac gtcaacgtat cggtattgcc cgtgccttgg tcatgcaacc agactttgtt
    18001 attgcagatg agccaatttc agccttggac gtttctgtac gtgcccaagt cttgaacttg
    18061 ctcaaaaaat tccaaaaaga gctcggcctg acctatctct tcatcgccca tgacttgtcg
    18121 gttgttcgct ttatttcaga tcgtatcgca gttatttaca agggtgttat tgtagaggtt
    18181 gcagaaacag aagaattgtt taacaatcca attcacccat atactcaagc cttgctttca
    18241 gcggtaccaa tcccagatcc aatcttggaa cgtaagaagg tcttgaaggt ttacgaccca
    18301 agtcaacacg actatgagac tgataagcca tctatggtag aaatccgtcc aggtcactat
    18361 gtttgggcga accaagccga attggcacgt tatcaaaaag gactaaacta ataatggttt
    18421 tataatttcc atgtcaattt ttatgggaat tataaaactt ttttgttgga ctgatttgaa
    18481 aaactttgaa agcttcctga aaga
//
LOCUS       DAVBEO010000046        17718 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 009
            SAMEA1678075-rid20185393.denovo.046, whole genome shotgun sequence.
ACCESSION   DAVBEO010000046 DAVBEO010000000
VERSION     DAVBEO010000046.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678075
            Sequence Read Archive: ERR226392
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 17718)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17718)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980207.1
            Genome Coverage       :: 150x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:50:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 72 of 147
            Pseudo Genes (incomplete)         :: 72 of 147
            Pseudo Genes (internal stop)      :: 42 of 147
            Pseudo Genes (multiple problems)  :: 32 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17718
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678075-rid20185393.denovo.046"
                     /strain="KS 009"
                     /db_xref="taxon:1313"
     gene            complement(122..1972)
                     /locus_tag="VQ543_001623"
     CDS             complement(122..1972)
                     /locus_tag="VQ543_001623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HET2612314.1"
                     /translation="MNKKLTDYVIDLVEILNKQQKQVFWGIFDIFSMVVSIIVSYILF
                     YGLINPAPVDYIIYTSLAFLFYQLMVDFWGLSASISRYSKITDFMKIFFGVTASSVLS
                     YSICYAFLPLFSIRFIILFILLSTFLILLPRITWQLIYSRRKKGSGDGEHRRTFLIGA
                     GDGGALFMDSYQHPTSELELVGILDKDSKKKGQKLGGIPVLGSYDNLPELAKRHQIER
                     VIVAIPSLDPSEYERILQMCNKLGVKCYKMPKVETVVQGLHQAGTGFQKIDITDLLGR
                     QEIRLDESRLGAELTGKTILVTGAGGSIGSEICRQVSRFNPERIVLLGHGENSIYLVY
                     HELIRKFQGIDYVPVIADIQDYDRLLQVFEQYKPAIVYHAAAHKHVPMMERNPKEAFK
                     NNIRGTYNVARAVDEAKVPKMVMISTDKAVNPPNVMGATKRVAELIVTGFNQRSQSTY
                     CAVRFGNVLGSRGSVIPVFERQIAEGGPVTVTDFRMTRYFMTIPEASRLVIHAGAYAK
                     DGEVFILDMGKPVKIYDLAKKMVLLSGHTESEIPIVEVGIRPGEKLYEELLVSTELVD
                     NQVMDKIFVGKVNVMPLESINQKIGEFRTLSGDELKQAIIAFANQTTHIE"
     gene            complement(2040..3179)
                     /locus_tag="VQ543_001624"
     CDS             complement(2040..3179)
                     /locus_tag="VQ543_001624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000096190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HET2612315.1"
                     /translation="MSSKVSGFQDKNGKVLKIMIEWWKGKFRRVVVTQNVESLLVSIV
                     ISAYNEEKYLPGLIEDLKNQTYPKENIEILFINAMSTDGTTAIIQQFIKEDAEFNSIR
                     LYNNPKKNQASGFNLGVKHSVGGLILKIDAHSKVTESFVMNNVAVIQQGEFVCGGPRP
                     TIVKGKGKWAETLHLVEENMFGSSIANYRNSSEDRYVSSIFHGMYKREVFQKVGLVNE
                     QLGRTEDNDIHYRIREHGYKIRYSPSILSYQYIRPTFKKMLHQKYSNGLWIGLTSHVQ
                     FKCLSLFHYVPCLFVLSLVFSLALLPITFVFITLLLGAYFLLLSLLSLLTLLTLLKHK
                     NGFLIVMPFLLFSIHFAYGLGTIVGLIRGFKWKKEYKGTVIYLEK"
     gene            3237..4403
                     /locus_tag="VQ543_001625"
     CDS             3237..4403
                     /locus_tag="VQ543_001625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CynX/NimT family MFS transporter"
                     /protein_id="HET2612316.1"
                     /translation="MKKQSLFFVPGIILIGVSLRTPFTVLPIILGNISQGLEVEVSSL
                     GVLTSLPLLMFTLFSPFSTRLAQKIGLEHLFTYSLFFLTIGSLIRLINLPLLYLGTLM
                     VGASVAVINVLLPSLIQANQPKKIGFLTTLYVTSMGIATALASYLAVPITQASSWKGL
                     ILLLTLLCLATFLVWLPNHRYNHRLAPQTKQKSQIKVMRNKQVWAIIIFSGFQSLIFY
                     TAMTWLPTMSIHAGLSSHEAGLLTSILSLISIPFSMTIPSLTTSLSTRNRQLMLTLVS
                     LAGVVGISMLFFPINNFIYWLAIHLLIGTATSALFPYLMVNFSLKTSAPEKTAQLSGL
                     SQTGGYILAAFGPTLFGYSFDLFHSWVPAVAALLLIDILMTVALFTVDRADKIL"
     gene            4542..4868
                     /locus_tag="VQ543_001626"
     CDS             4542..4868
                     /locus_tag="VQ543_001626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000273865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HET2612317.1"
                     /translation="MYFPTSSALIEFLILAVLEQGDSYGYEISQTIKLIANIKESTLY
                     PILKKLEGNSFLTTYSREFQGRMRKYYSLTNGGIEQLLTLKDEWTLYTDTINGIIEGS
                     IRHDKN"
     gene            4855..5448
                     /locus_tag="VQ543_001627"
     CDS             4855..5448
                     /locus_tag="VQ543_001627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000198695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1700 domain-containing protein"
                     /protein_id="HET2612318.1"
                     /translation="MTRTEYLTQLELYLKKLPEADRIEAMDYFRELFDDAGVEGEEEL
                     IASLGTPKEVAHEVLSNLLDKKINEAPAQKNNRQILHIALLALLAAPIGIPLGIAILV
                     TLFAILVAALTVILAFFAVSILGIIGGFLFLVESFTVLAQAKSAFILIFGSGLLAIGA
                     SSLVLLGISYVARFFGLLIVRLVQFVLKKGKRGNQHA"
     gene            5441..6352
                     /locus_tag="VQ543_001628"
     CDS             5441..6352
                     /locus_tag="VQ543_001628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001233690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4097 domain-containing protein"
                     /protein_id="HET2612319.1"
                     /translation="MRKWTKGFLIFGVVTTVIGFILLFVGIQSDGIKSLLSMSKEPVY
                     DSRTEKLTFGKEVENLEITLHQHTLTITDSFDDQIHISYHPSLSAHHDLITNQNDRTL
                     SLTDKKLSETPFLSSGIGGILHIASSYSSRFEEVILRLPKGRTLKGINISANRGQTTI
                     INASLENATLNTNSYILRIEGSRIKNSKLTTPNIVNIFDTVLTDSQLESTENHFHAEN
                     IQVHGKVELTAKDYLRIILDQKESQRINWDISSNYGSIFQFTREKPESRGTELSNPYK
                     TEKTDVKDQLIARSDDNIDLISTPSRR"
     gene            6415..7479
                     /locus_tag="VQ543_001629"
     CDS             6415..7479
                     /locus_tag="VQ543_001629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2612320.1"
                     /translation="MKQEWFESNDFVKTTSKNKPEEQAQEVADKAEETIADLDTPIGK
                     NTQVEEEVSQAEVELESQQEEKIETPEGGEARTEIEEKKASNSTEEEPDLSKETEKVT
                     IAEESQEALPQQKATTKEPLLISKSLESPYIPDQAPKSRDKWKEQVLDFWSWLVEAIK
                     SPTSKLETSITHSYTAFLLLILFSASSFFFSIYHIKHAYYGHIASINSRFPEQLAPLT
                     LFSIISILVATTLFFFSFLLGSFVVRRFIHQEKDWTLDKVLQQYSQLLAIPIFLTAIA
                     SFFAFFDSLRFTALLCVISIGIILLASLHIITRPSQASETDSFYQLFLSVLVNGVIIL
                     LFFVAEVALIGDYLRILAFL"
     gene            complement(7551..8411)
                     /locus_tag="VQ543_001630"
     CDS             complement(7551..8411)
                     /locus_tag="VQ543_001630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4299 domain-containing protein"
                     /protein_id="HET2612321.1"
                     /translation="MAKTFFIPNKQSILGEQEILNAKSILALLDGLESHIYDVVYLRQ
                     PLNRLEYIECAIVGQSQFLFKVSYADGQKAYRVDLPDLLTETDWQIIKSFLDALLAYT
                     GTDIEGLDGFDFEAYFQASIQAYLADPVARFTICQGIFNPIFFSRENLKSFLEADGLA
                     QFEARVRAVQETDAYFARVSFYQDGEGKVHGVYHLAQGVKTVLPREPFVPAAYIEQLV
                     DKEVQWEIDLVQITGDGSKPEDYEAIARLDYAKFLEVLPPSFYHQLDANQIEVQPILD
                     KDFKTLAQEK"
     gene            complement(8533..9519)
                     /locus_tag="VQ543_001631"
     CDS             complement(8533..9519)
                     /locus_tag="VQ543_001631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001030014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-related sulfurtransferase"
                     /protein_id="HET2612322.1"
                     /translation="MAKDIRVLLYYLYTPIENAEQFAADHLAFCKSIGLKGRILVADE
                     GINGTVSGDYETTQKYMDYVHSLPGMEELWFKIDEENEQAFKKMFVRYKKEIVHLGLE
                     DNDFDNDINPLETTGAYLSPKEFKEALLDKDTVVLDTRNDYEYDLGHFRGAIRPDIRN
                     FRELPQWVRDNKEKFMDKRVVVYCTGGVRCEKFSGWMVREGYKDVGQLHGGIATYGKD
                     PEVQGELWDGKMYVFDERIAVDVNHVNPTIVGKDWFDGTPCERYVNCGNPFCNRRILT
                     SEENEDKYLRGCSHECRVHPRNRYVSKNELTQAEVIERLAAIGESLDQAATV"
     gene            complement(9791..11266)
                     /locus_tag="VQ543_001632"
     CDS             complement(9791..11266)
                     /locus_tag="VQ543_001632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000800432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3502 domain-containing protein"
                     /protein_id="HET2612323.1"
                     /translation="MKNWKKYAFASASVVALAAGLAACGNLTGNSKKAADSGDKPVIK
                     MYQIGDKPDNLDELLANANKIIEEKVGAKLDIQYLGWGDYGKKMSVITSSGENYDIAF
                     ADNYIVNAQKGAYADLTELYKKEGKDLYKALDPAYIKGNTVNGKIYAVPVAANVASSQ
                     NFAFNGTLLAKYGIDISGVTSYETLEPVLKQIKEKAPDVVPFAIGKVFIPSDNFDYPV
                     ANGLPFVIDLEGDTTKVVNRYEVPRFKEHLKTLHKFYEAGYIPKDVATSDTSFDLQQD
                     TWFVREETVGPADYGNSLLSRVANKDIQIKPITNFIKKNQTTQVANFVISNNSKNKEK
                     SMEILNLLNTNPELLNGLVYGPEGKNWEKIEGKENRVRVLDGYKGNTHMGGWNTGNNW
                     ILYINENVTDQQIENSKKELAEAKESPALGFIFNTDNVKSEISAIANTMQQFDTAINT
                     GTVDPDKAIPELMEKLKSEGAYEKVLNEMQKQYDEFLKNKK"
     gene            complement(11370..12293)
                     /locus_tag="VQ543_001633"
     CDS             complement(11370..12293)
                     /locus_tag="VQ543_001633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001075101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HET2612324.1"
                     /translation="MAKKKIKKEKIDNVGIHSFSKKADIFFSIISGLIALSCILPFVF
                     VIIISVTDEKSLLQYGYSFFPSQFGLDGFEFLAQFKDKILQALFISVFVTVVGTLTNV
                     FITTTYAYAISRTTFKYRRFFTIFVLLSMLFNAGLVPGYIMVTRVLQLGDTVWALIVP
                     MLLSPFNIILMRSFFKKTIPEAILESARIDGASEARIFFQICLPLSLPGIATITLLTA
                     LGFWNDWFNALLYIKSDNLYPLQYLLMQIQQNMDYIAKAVGLTGQLGVALPKETGRMA
                     MVVVATLPIAILYPFFQRYFVKGLTIGGVKE"
     gene            complement(12307..13236)
                     /locus_tag="VQ543_001634"
     CDS             complement(12307..13236)
                     /locus_tag="VQ543_001634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HET2612325.1"
                     /translation="MKKFSKTLRDNWIFLLMVLPGALWLILFFYIPVFGNVVAFKDYH
                     MTSNGFIDSIINSKWVGLDNFRFLFSSRDAFIITRNTVLYNLGFIFLGLVVSVGIAII
                     LSELRSKRMVKIFQTSMLFPYFLSWVIISFFTDAFLNIDKGVFNHLLESLGLKEVNFY
                     ADLGIWPYLLLFLGIWKGFGYSSVMYYATIMGIDPTYYEAATVDGASKWQRIRNVTIP
                     QLTPLVTVLTILAVGNIFRADFGLFYQIPHNAGQLYNVTNVLDVYVFNGLTQTADIGM
                     AAAAGLYQSVVGLILVILSNLLARRVDPNSALF"
     gene            complement(13555..13905)
                     /locus_tag="VQ543_001635"
     CDS             complement(13555..13905)
                     /locus_tag="VQ543_001635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000148255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2612326.1"
                     /translation="MTGVSNPTTDSARLVLAEAKKAFADDSLTEQGLRDILQTVKDAI
                     ASLESIKESQSATKDGGQTAGKETADKDVLENSQEELQKAVLFLADEKGSEHTEAELI
                     DNLKEVIAKLKANA"
     gene            complement(14331..14486)
                     /locus_tag="VQ543_001636"
                     /pseudo
     CDS             complement(14331..14486)
                     /locus_tag="VQ543_001636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            complement(14672..15283)
                     /gene="rpsD"
                     /locus_tag="VQ543_001637"
     CDS             complement(14672..15283)
                     /gene="rpsD"
                     /locus_tag="VQ543_001637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S4"
                     /protein_id="HET2612327.1"
                     /translation="MSRYTGPSWKQARRLGLSLTGTGKELARRNYVPGQHGPNNRSKL
                     SEYGLQLAEKQKLRFTYGVGEKQFRNLFVQATKIKGGILGFNFMLLLERRLDNVVYRL
                     GLATTRRQARQFVNHGHILVDGKRVDIPSYRVTPGQVISVREKSLKVPAILEAVEATL
                     GRPAFVSFDAEKLEGSLTRLPERDEINPEINEALVVEFYNKML"
     gene            complement(15478..16530)
                     /locus_tag="VQ543_001638"
     CDS             complement(15478..16530)
                     /locus_tag="VQ543_001638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000769768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HET2612328.1"
                     /translation="MKLKSYILVGYIISTLLTILVVFWAVQKMLIAKGEIYFLLGMTI
                     VASLVGAGISLFLLLPVFTSLGKLKEHAKRVAAKDFPSNLEVQGPVEFQQLGQTFNEM
                     SHDLQVSFDSLEESEREKGLMIAQLSHDIKTPITSIQATVEGILDGIIKESEQAHYLA
                     TIGRQTERLNKLVEELNFLTLNTARNQVETTSKDSIFLDKLLIECMSEFQFLIEQERR
                     DVHLQVIPESARIEGDYAKLSRILVNLVDNAFKYSAPGTKLEVVTKLEKGQLSISVTD
                     EGQGIAPEDLENIFKRLYRVETSRNMKTGGHGLGLAIARELAHQLGGEITVSSQYGLG
                     STFTLVLNLSGSENKA"
     gene            complement(16527..17225)
                     /locus_tag="VQ543_001639"
     CDS             complement(16527..17225)
                     /locus_tag="VQ543_001639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000520636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET2612329.1"
                     /translation="MGKTILLVDDEVEITDIHQRYLIQAGYQVLVAHDGLEALELFKK
                     KPIDLIITDVMMPRMDGYDLISEVQYLSPEQPFLFITAKTSEQDKIYGLSLGADDFIA
                     KPFSPRELVLRVHNILRRLHRGGETELISLGNLKMNHSSHEVQIGEEMLDLTVKSFEL
                     LWILASNPERVFSKTDLYEKIWKEDYVDDTNTLNVHIHALRQELAKYSSDQTPTIKTV
                     WGLGYKIEKPRGQT"
     gene            complement(17392..>17718)
                     /locus_tag="VQ543_001640"
     CDS             complement(17392..>17718)
                     /locus_tag="VQ543_001640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HET2612330.1"
                     /translation="VKETSDTANGSLSPSNSGSGVTPMNHNHATGTTDSMPADTMTSS
                     TNTMAGENMAASANKMSDTMMSEDKAMLPNTGETQTSMASIGFLGLALAGLLGGLGLK
                     NKKEEN"
BASE COUNT         5256 a         3831 c         3281 g         5350 t
ORIGIN      
        1 aaccatatac ggcaaggcga cgttgacgtg atttgaagag attttcgaag agtataagtc
       61 tctacataat aaaacgcata ttaccaaggt tatttaactt gataatatgc gtttttcttt
      121 tttattcaat gtgggttgtt tgattagcaa aggcgataat agcttgcttc aactcatctc
      181 cactgagagt gcggaactct ccaatctttt gattgatgga ttctaaaggc atgacattaa
      241 ccttaccaac gaaaatctta tccataactt gattatcaac gagttcggtt gataccaaga
      301 gttcttcgta gagtttttca cctgggcgga ttccaacttc aacgattgga atttcacttt
      361 cagtgtggcc acttagaagc accatcttct tggccaagtc ataaatcttg actggtttgc
      421 ccatatcaag gataaagact tccccatctt tggcataagc accagcatgg ataaccagac
      481 ggctagcttc tggaatggtc ataaagtaac gggtcatgcg gaagtctgtc accgttacag
      541 gcccaccttc agcaatctga cgttcaaaga ctggaatgac actaccacgg ctaccaagaa
      601 cattcccaaa acgaactgca cagtaggttg attggctacg ttggttaaag ccagtgacaa
      661 tcaactccgc cacgcgcttg gttgctccca taacatttgg tggattgact gccttatctg
      721 tcgaaatcat aaccatctta ggcaccttgg cttcatcaac ggctctagca acattgtaag
      781 ttccacggat attgtttttg aaggcttctt ttggattgcg ctccatcata ggaacatgct
      841 tgtgggctgc cgcatgataa acaatagcag gtttgtactg ctcaaagact tgcaacaaac
      901 gatcatagtc ttgaatgtcc gcaatcacag gtacataatc aatcccttgg aacttacgaa
      961 tcaattcatg ataaacaagg tagattgagt tttccccatg accgagcaag acaatgcgtt
     1021 caggattgaa gcgactaact tgacgacaga tttcagaacc gattgaacct ccagctcctg
     1081 tgactaagat ggtcttacct gtcagttctg cacccagacg cgattcgtca agacggattt
     1141 cctgacgacc caaaaggtcc gtaatatcaa ttttttggaa gccagtacct gcttggtgaa
     1201 ggccctgaac aacagtttca accttaggca tcttgtaaca tttgacaccc agcttattac
     1261 acatctgcaa gatacgctca tattctgacg gatccagcga cggaatcgca acgatgacac
     1321 gctcgatttg atggcgtttg gctaattcag gcagattgtc ataagagccc aaaacaggaa
     1381 taccaccaag tttttgaccc tttttcttag aatccttatc caaaataccg accagttcta
     1441 attcactggt tggatgttgg taactatcca taaagagagc cccaccatca ccggcaccaa
     1501 tcaagaaggt ccgacggtgt tctccatcac cactaccttt tttgcgtctg gagtagatta
     1561 actgccaagt aatccgtggc aataaaatca agaaggtact caacaagata aagagaatga
     1621 taaaacggat ggagaagagt ggcaagaagg cataacagat actatatgac aagacactgc
     1681 tagcagtcac accaaaaaag attttcatga aatccgtaat cttgctgtaa cgactaatac
     1741 tcgcgctcaa gccccaaaaa tcaaccatca attgatagaa caggaaggcc aaactcgtat
     1801 agataatgta gtcaacaggt gctggattaa tcagcccata aaataaaata taagatacaa
     1861 tgatggaaac caccatactg aaaatatcaa atattcccca gaaaacctgc ttttgttgtt
     1921 tatttaaaat ttccaccaga tcaatcacat aatctgtgag ttttttattc atagaaattt
     1981 actcctcctt aaaatagttc tactatattg ttattatagc acattttaat ttatttggct
     2041 tatttttcca aataaattac tgttcccttg tactccttct tccatttaaa tcctctaatt
     2101 aaacctacaa tcgtcccaag gccataagca aagtgaatgg aaaataaaag aaagggcatc
     2161 acaattagaa atccattttt atgttttaat aaagtcagca aagtgagtaa tgacagtaat
     2221 gataaaagta gaaaataggc acctaatagt aaagttatga atacgaatgt gatcggtaac
     2281 aatgctagac taaacacaag actcaaaaca aataaacaag gaacataatg aaataatgat
     2341 aaacacttaa actgaacatg acttgtcaag ccaatccaca aaccatttga atacttttga
     2401 tgcagcattt tcttgaatgt tggtcgaata tactgataag atagaatact tgggctatag
     2461 cggattttat aaccatgttc tcgaattcta taatgaatat cattatcttc agttcggcca
     2521 agttgctcat ttactaaacc aaccttctgg aaaacctctc gtttatacat cccatgaaaa
     2581 atagaagaaa catatctatc ctcggaacta tttcgataat tggcaatgct actgccaaac
     2641 atattttcct caacaagatg caaggtctct gcccattttc cttttccttt gacaatcgtc
     2701 ggtctaggcc ctccacagac aaattcacct tgttgaataa cagccacatt gttcattaca
     2761 aaactctcag taacttttga atgagcatca atttttaaaa taaggccccc tacagaatgc
     2821 ttaactccca ggttaaaacc actagcttga tttttcttag gattgttata caatctaatt
     2881 gagttaaact ctgcatcttc ttttataaat tgctgaatga tagctgtggt cccatctgtg
     2941 gacatagcat ttataaatag aatttcaata ttctctttag gataggtttg attttttaag
     3001 tcttcaatta gaccaggcag atatttttct tcattgtatg cactgattac aatggatacg
     3061 agaagacttt caacattttg agtcactact actctcctga attttccctt ccaccattct
     3121 atcataattt tcaagacttt tccattttta tcttgaaagc cagaaacctt acttgacatt
     3181 atagtgaaaa agccttaaaa taagctgtta ttaaaatcag ctagaagaga tattatatga
     3241 aaaagcaatc actctttttt gttccaggta ttatcctgat tggtgtttcc ttgcgaactc
     3301 cttttactgt tttacccatt attttgggaa atatttcgca aggtctggag gtagaagtta
     3361 gttcgcttgg tgtcttgacc agcctgcctc tccttatgtt taccctcttt tcaccatttt
     3421 ctacccgact ggctcagaaa atcggcttgg agcatctctt cacctacagc ctcttcttct
     3481 tgaccatcgg ctcacttatt cgactaatca atctgcccct gctctatcta ggaaccttga
     3541 tggttggggc aagtgtcgca gtcatcaatg tcctgcttcc tagtcttatc caagccaatc
     3601 aaccaaagaa aattggtttt ctgaccacct tatatgtaac gtctatgggg attgcaacgg
     3661 ctctggcttc ctatctagct gtgcccatta cacaagccag ttcttggaaa ggacttatcc
     3721 tcctcctcac gttactctgt ctagcaactt ttttggtctg gctcccaaat caccgctata
     3781 atcatagact agctccacaa accaaacaaa aaagtcaaat aaaggtcatg cgtaataaac
     3841 aggtttgggc aattattatc ttttcaggtt ttcaatcctt gatcttttac accgccatga
     3901 cctggttacc taccatgtct atccatgcag gtctatccag tcacgaagct ggcttgctga
     3961 cttctatctt atctctgatt agcattcctt tttcaatgac catcccaagc ctgacaacca
     4021 gtttatctac tcgcaaccgt cagctcatgc tcactctggt ttcactagct ggtgtggtcg
     4081 gcatttccat gctctttttc ccaatcaata atttcattta ctggcttgcc atccatctcc
     4141 tcatcggaac cgcaaccagc gccctcttcc cttatctcat ggtcaacttt tcactcaaga
     4201 ccagcgcccc tgaaaagaca gcccaattgt ccggcctatc tcaaacagga ggctatatcc
     4261 tagcagcctt tgggccaacc ctctttggtt acagttttga cctattccac tcttgggtac
     4321 cagctgtagc tgccctcttg ctcatcgata tcctgatgac tgtggccctc tttacagtgg
     4381 acagagcgga taagatcctt taaacttcta gttttagcta gaagtttttt atatataaaa
     4441 attttacaca tttctcttga cagggctttc ttttagatgt acaatgtatg tgtagaaaaa
     4501 ttatatataa aaatcttaca cattagaaaa ggaggtttcc catgtacttt ccaacatcct
     4561 ctgccttgat tgaatttctc atcttggctg tactggagca gggtgattct tatggttatg
     4621 agattagcca aaccattaag ctgatcgcta atatcaaaga atccacactc tatcccattc
     4681 tcaaaaaatt ggaaggcaat agctttctga caacctattc tagagagttc caaggtcgca
     4741 tgcgcaaata ctactccttg acaaacggtg gtatagagca gctcttgacc ctaaaagatg
     4801 aatggacact ctatacagac accatcaatg gcatcataga agggagtatc cgccatgaca
     4861 agaactgaat acctgactca gctagaactc tatctcaaga aactacctga agctgaccgt
     4921 atcgaagcca tggactattt cagagagctc tttgacgatg ctggagtcga aggagaagaa
     4981 gaactcatcg ctagtttggg aactcccaaa gaagtggccc acgaagttct atccaatctt
     5041 ctcgataaaa aaatcaatga agcacccgct caaaaaaata accgacaaat tttacatatc
     5101 gccttgttag ccctccttgc agcacctatc ggcattcctc tgggaatcgc catcctcgtg
     5161 accctgttcg caatccttgt agccgctttg actgtcattc tggctttctt tgcagtttcc
     5221 atactgggta tcatcggcgg attcctattt ttagttgaaa gtttcactgt cctcgcccaa
     5281 gccaaatcag cctttatctt gatttttggt tctggtttac tggctatcgg tgcttcttcg
     5341 ctagttttac ttggcatttc ctatgtagct cgcttcttcg gtctactcat tgttcgtctg
     5401 gtacaatttg ttcttaaaaa aggaaagaga ggtaatcagc atgcgtaaat ggacaaaagg
     5461 atttctcatc tttggtgtgg tgactaccgt tatcggcttt atcctgcttt ttgtaggtat
     5521 ccaatctgac gggattaaga gcctactttc catgtccaaa gaacctgtct atgatagccg
     5581 tacggaaaag ctaacctttg gcaaggaagt cgaaaaccta gaaattactc tccaccaaca
     5641 cacgctcacc atcacagact ctttcgatga tcaaatccac atttcttacc atccatctct
     5701 ttctgctcac catgatctta tcaccaatca gaacgataga actctgagtc tcactgataa
     5761 gaaactgtct gaaactccgt ttctctcttc tggaattggt gggattcttc atatcgcaag
     5821 tagctactct agtcgttttg aagaagttat tctccgacta ccaaaaggga gaactctaaa
     5881 agggatcaac atctcagcca atcgcggaca aaccaccatc ataaatgcta gccttgaaaa
     5941 tgcgaccctc aatacaaaca gctatatcct ccgaattgaa ggaagtcgta tcaaaaacag
     6001 taaactcaca acgcccaata tcgttaatat ctttgataca gttcttacag atagtcagct
     6061 agagtcaaca gagaatcact tccacgctga aaatatccaa gtccatggta aggttgaact
     6121 gactgccaaa gattatctca gaatcatcct agaccagaaa gaaagccaac gaattaactg
     6181 ggacatctca agcaactatg gttctatctt ccaattcaca agagaaaagc ctgaatcaag
     6241 aggtacggaa ttaagcaacc cttacaaaac tgaaaaaacc gatgtcaagg atcaactcat
     6301 tgcgagatct gatgataata ttgatctaat atccacacca agcagacgtt gacaaaaacg
     6361 cttacatctg ctactatgga agcatattta tctaactaaa aaggaggttc taccatgaaa
     6421 caagaatggt ttgaaagtaa tgattttgta aaaacaacaa gcaagaacaa gcctgaagag
     6481 caagctcaag aggttgcaga caaggctgaa gaaacgatag ccgatctcga tacaccaatt
     6541 ggaaaaaata ctcaagtaga ggaggaagtc tctcaagctg aagtcgaact ggaaagccag
     6601 caagaagaga aaattgaaac tcctgaaggc ggtgaagcga gaacagaaat agaagaaaag
     6661 aaggcatcta attctactga agaagagcca gacctttcta aagaaacaga aaaagtcact
     6721 atagctgaag agagccaaga agctcttcct cagcaaaaag caaccacgaa agagccactt
     6781 cttatcagta aatctttaga aagtccttat atccccgacc aagctccaaa atctagggat
     6841 aaatggaaag agcaagtgct tgatttttgg tcttggctag tggaagcgat caaatctcct
     6901 acaagtaagt tggaaacaag tatcacacac agttacacag cctttctctt gctcattctg
     6961 ttttctgcat cttccttttt ctttagtatc tatcacatca aacatgctta ctatggacat
     7021 atagcaagca ttaacagtcg cttccctgag cagctagctc ctttaactct tttttctatc
     7081 atctctatcc tagtagcgac aacactcttc ttcttttcat tcctcttggg tagtttcgtt
     7141 gtgagacgat ttatccacca ggaaaaggac tggacgctag acaaggttct ccaacaatat
     7201 agtcaactct tggcaattcc aatcttcctc actgctattg ctagtttctt tgctttcttt
     7261 gatagcctac gatttacggc cctcttgtgt gtgattagca ttggaatcat tctgcttgcc
     7321 agtctccata tcattacaag accaagtcaa gcaagtgaaa ccgactcctt ctatcaatta
     7381 ttcttgtctg tccttgtgaa cggagttatt atcctcctct tctttgtagc tgaagtggca
     7441 ctgattggag attatcttcg tatcttggcc tttctttaaa attcaatcct gtcatccttg
     7501 gcaggatttt ttctatgtca aaaaagcaag tcgattgacc tgcttctgct ttacttttct
     7561 tgtgctaatg ttttaaaatc tttgtctaat atgggttgca cttctatttg attggcgtct
     7621 agttggtggt aaaaagatgg gggtaatacc tctaagaatt ttgcatagtc caagcgagca
     7681 atggcttcat agtcttctgg tttagagcca tctcctgtga tttgaaccaa gtcaatctcc
     7741 cactgcactt ccttatccac caattgctca atataggctg caggaacaaa cggttctctc
     7801 ggtaaaactg tcttgactcc ttgagctaga tggtaaacgc catgcacttt tccttctcca
     7861 tcctgataga aggaaactct cgcaaagtag gcatctgtct cttgaaccgc acgcacacgc
     7921 gcttcaaact gagccaaacc atctgcctct aaaaagcttt tcaagttctc acgactaaag
     7981 aaaataggat taaaaattcc ttggcaaatc gtaaaacgag ctacagggtc tgctagatag
     8041 gcttgaatac ttgcttggaa ataagcttca aaatcaaaac catctagccc ttcaatatca
     8101 gtccctgtat aagcaagcaa agcatctaaa aatgacttga taatctgcca gtctgtctct
     8161 gttagtaggt caggaagatc gacacggtaa gccttttgac catcagcata actgacctta
     8221 aaaagaaatt gtgattgccc cactatcgca cactcaatat actcgagacg attaagaggc
     8281 tgacggagat agactacatc atagatatgt gactccaaac cgtctagcaa tgccaagatc
     8341 gacttggcat tcaaaatctc ttgttctcct aaaatgctct gtttatttgg aataaaaaat
     8401 gttttcgcca taactggact cctttgaaat cgcttacata cagtatacct tatttttctg
     8461 aaagatacag aaacaaactt tagatttttg agtacaaagc atagaaaaac agcccctgag
     8521 gactgtttga tcttatacag tagctgcttg atccaagctt tcaccgatag cggctaggcg
     8581 ctcgatcact tcagcttgtg tcaattcatt ttttgaaaca tagcggttac gtgggtgaac
     8641 acggcactcg tgtgagcatc cacgaaggta cttgtcttca ttttcttctg atgtcaagat
     8701 acgacggtta cagaagggat ttccacagtt gacataacgt tcacatggtg ttccatcaaa
     8761 ccagtctttc cctacgatgg ttgggttgac atggttgaca tcaacggcga tacgctcgtc
     8821 aaatacgtac atttttccat cccaaagctc accttgaact tctgggtctt taccgtaagt
     8881 tgcgattcct ccgtgcaatt ggccgacatc tttgtagcct tcacggacca tccagcctga
     8941 gaatttctca cagcgaacgc cacctgtaca gtaaaccacg acacgcttgt ccatgaattt
     9001 ttccttgtta tcacggaccc attgtggtaa ctcacggaag ttgcgaatat ctgggcgaat
     9061 agctccacgg aaatgtccta ggtcgtactc ataatcgtta cgtgtgtcaa ggacaacggt
     9121 atctttatca agaagcgctt ctttgaactc ttttggagac aagtaagcac ctgttgtttc
     9181 aagtgggttg atgtcattgt caaagtcgtt gtcttccaaa ccaaggtgga caatttcttt
     9241 cttgtagcga acaaacatct tcttgaaggc ttgttcattt tcttcgtcaa tcttgaacca
     9301 gagttcttcc attcctggaa ggctgtgaac gtagtccatg tatttttgag ttgtttcata
     9361 gtcacctgaa actgttccgt taattccctc gtcagcgact aggatacggc ctttaagacc
     9421 gattgattta cagaaagcca agtggtctgc agcaaattgc tctgcatttt caattggagt
     9481 ataaaggtag taaagtaaga cacgaatatc ttttgccata agatttgttc tcttttctat
     9541 tcttaaattt tctaaatttt ttatttatcc atactagtat acctgcttga gaaaacgaat
     9601 gcaatttatt tgactggaaa ttgtagagga ttctcgaaat ttcctgaatg gttaaaataa
     9661 ggacaagaga aaacatggat atctatatcc ttgtgccaaa aaaaccactg ccctccccag
     9721 accaacctga ggaaagcagt gattcttatt ttaggagtta ggaatgaata cacgaaatca
     9781 atttagctga ttattttttg tttttcaaga attcatcgta ttgtttttgc atttcgttca
     9841 atactttttc gtaggcacct tcagatttca atttttccat caattctgga atcgctttat
     9901 ctgggtctac agtaccagtg ttgatagctg tatcaaattg ttgcattgtg ttagcaatag
     9961 ctgagatttc agatttcaca ttgtcagtat tgaagataaa tccaagcgct ggagattctt
    10021 tagcttctgc caattctttc ttagaatttt cgatttgttg gtctgtaacg ttttcgttga
    10081 tgtaaaggat ccagttgtta ccagtgttcc atccacccat gtgagtgttt cctttgtagc
    10141 catcaagaac gcgaacacgg ttttctttac cttcaatttt ttcccagttc ttgccttctg
    10201 gaccgtaaac aagaccgttc aaaagttctg ggttcgtatt caagaggttc aagatttcca
    10261 ttgatttttc tttgttctta gagttgtttg agatgacaaa gttagcaact tgtgttgttt
    10321 ggtttttctt gatgaagtta gtgattggtt tgatttggat atctttgttg gcaacacgtg
    10381 aaagcaagct gttaccgtag tcagctggtc ctactgtttc ttcacgaacg aaccaagtat
    10441 cttgttgaag gtcaaatgaa gtatcgcttg ttgcgacgtc ttttggaatg tagccagctt
    10501 catagaattt gtgaagagtc ttcaagtgtt ctttgaaacg aggcacttcg taacggttta
    10561 caactttagt agtatcgcct tcaaggtcaa taacgaatgg aagcccgttt gctactgggt
    10621 agtcaaaatt atcagatggg atgaaaactt taccaatagc aaatggtact acgtctggag
    10681 ctttttcttt gatttgtttc aagactggct caagagtttc gtaagaagta acacctgaaa
    10741 tatcgatacc atatttggca aggagagttc cgttgaaggc aaagttttga gatgatgcta
    10801 cgttggctgc aactggtaca gcataaatct taccatttac agtattaccc ttgatataag
    10861 ctggatcaag tgccttgtaa aggtctttac cttctttttt gtacaattct gtcaagtcag
    10921 cataagcacc tttttgagca tttacaatat agttatctgc aaaggcgata tcatagtttt
    10981 caccagatga tgtgataact gacattttct taccatagtc accccagcca aggtattgga
    11041 tatccaattt ggcaccaact ttttcttcga tgattttgtt ggcatttgct aacaattcat
    11101 ccaagttatc tggtttgtca ccgatttggt acattttgat aacaggtttg tcacctgaat
    11161 cagcagcttt tttgctgtta cctgtcaaat ttccacaagc agcaagacct gcagccagag
    11221 cgactacact agcagatgca aaagcatatt ttttccagtt tttcatgata aaaactcctt
    11281 tttttatttt taaacttata aacaatgtaa tgatcttaac ttcacacaag ggaagttggg
    11341 aactgagaaa tgttcttttt caataagcac tattctttca caccaccgat agtcaaacct
    11401 tttacaaagt agcgttggaa gaatggatac aaaatcgcga ttggaagggt tgctaccaca
    11461 accatggcca tacgacctgt ttctttcggt agagcaactc ccagttgacc agtcaagccg
    11521 accgctttgg caatgtagtc catattttgt tggatttgca tgagcaaata ttgcaatgga
    11581 tacaagttat cactcttgat gtaaagaagg gcgttgaacc agtcattcca gaaaccaaga
    11641 gctgtcaaaa gcgtgatggt tgcgatacct ggtagtgaca atggcaaaca gatttggaag
    11701 aaaatccgag cctcactggc accatcgata cgagccgatt cgagaatggc ttctggaatg
    11761 gtcttcttga aaaaagaacg catcaagatg atattgaatg gtgagagaag cattggaaca
    11821 atcaaggccc aaacagtgtc accaagctga agtacacggg tcaccatgat ataacctggt
    11881 accaaaccag cgttgaacaa catactgaga aggacgaaga tggtaaaaaa tctgcgatac
    11941 ttaaaggttg tccgtgaaat agcgtaggca taggttgttg tgataaagac atttgtcaat
    12001 gtcccaacta cggttacaaa gacagagatg aagagggctt gtaggatttt atccttaaac
    12061 tgtgccaaaa actcaaaacc gtctaagcca aattgggatg ggaagaagct atagccgtat
    12121 tggaggaggc ttttctcgtc tgtcactgaa ataatgataa cgaatacaaa aggtaggata
    12181 caagagaggg caatcaaacc cgaaatgata ctgaagaaga tatctgcttt cttactgaag
    12241 gagtgaatgc cgacattatc aattttttct tttttaattt tcttttttgc catattctcc
    12301 tcctttctag aacaaagctg agtttggatc gactcgtctt gcaagcaagt ttgataggat
    12361 aaccagaatc aaaccaacaa cggattggta aagaccggct gctgcagcca taccgatatc
    12421 tgctgtctga gtcaaaccat taaagacata tacgtccaaa acgttggtta cattgtaaag
    12481 ctgaccagca ttgtgtggga tttgatagaa gagaccgaag tctgcgcgga agatatttcc
    12541 gactgcaagg atggtcaata cagttacaag cggagtcaac tgaggaatgg ttacgttgcg
    12601 aatacgttgc cacttgctag ctccgtccac tgtcgctgct tcgtagtagg ttggatcaat
    12661 tcccatgatc gtcgcatagt acatgacact gctatatcca aagcctttcc aaatacctag
    12721 gaaaagtagg agatagggcc agatgcccag gtcagcgtag aaattgactt ctttgagacc
    12781 aagactttcc aatagatgat tgaacacccc tttatcaata tttaggaagg catctgtaaa
    12841 gaaactgatg ataacccaag acaagaagta agggaacaac atagaagttt gaaaaatctt
    12901 caccattctc ttagaacgga gctcgctgag gataatggca atccctacag atacaactaa
    12961 acctagaaag ataaagccaa gattgtagag gacagtattt cgtgtgataa taaaggcgtc
    13021 tcttgaacta aataagaatc tgaaattatc gagtccgacc catttactat ttatgatact
    13081 atctatgaaa ccattactgg tcatgtggta gtctttgaag gcaaccacgt tcccaaatac
    13141 tggaatgtaa aagaatagaa tcaaccagag tgcccctggc aaaaccatca agagaaagat
    13201 ccagttgtct ctcaatgttt ttgaaaactt tttcataatt tcctcccttt ttattttgat
    13261 atccatctaa aaattctttt ttagactttt gataacgatt acattattag tatactccta
    13321 tttgcaggtt aggttaaact cctaattata gaaaaaactc cacaaattat gtagcagatt
    13381 taaaacttta tcaccactat caaacaaatg tcctaaatca attgtttatt ttatctctat
    13441 tagcccagtg atggcgtcac tctgttataa gcatccaaca acggggtata ctgaaaaatc
    13501 tccagactag ggaactcagc gatagttcct aatctggaga tttttaatat gttattaggc
    13561 gtttgctttc aacttagcaa taacctcttt aagattatca atcaactctg cttcagtatg
    13621 ctcagagcct ttttcatctg ccaagaacaa aactgctttt tgaagttctt cttgagagtt
    13681 ttcaaggaca tccttatctg ctgtttcttt gcccgctgtt tgtcctccat ccttagttgc
    13741 tgactggctt tccttaatgg actctaggga agcaatggca tctttgactg tttgcaagat
    13801 atcacgtaaa ccttgctctg tcaaactatc atctgcaaaa gctttcttag cctctgccaa
    13861 aaccagacgt gctgaatctg tggtaggatt cgatacacct gtcaatgatc tcaaaagatt
    13921 ttctaaagtt tgagtctgct tactaatact agactaaaat caaaaagcat tatataacag
    13981 tgatatgaaa tcaactaaag aagaaatcca aactatcaaa acacttttaa aagactctcg
    14041 tacagctaaa tatcataaac gccttcaaat cgttctatag taaaatgaaa caagaacagg
    14101 acaaatcgat caggacagtc aaatcgattt ctaacaatgt tttagaagta gaggtgtact
    14161 attctagttt caatccatta tatttcgtct gatgggcaaa tcttataaag agattataga
    14221 acttttatag tagtttgaaa taagatgtga acaactctat caggaaagtc aaattaattt
    14281 atagaaatat tttagcagct aaggtgtact gttatagatt caatacacta tacttggtgg
    14341 tttagctctc ctgttttctc ttttagcttt aaccagccat aaatggtatt acgtgagatt
    14401 tggaaaacgt gtgatgcttc tgttatacta cctgttcgct cacaataaga gagaattttt
    14461 ttacgaaaat ctattgaata tgccataaaa ggattatacc acattgtgta ctatttttgg
    14521 ttcattttac tatatcactt tggactatat cggtctagtt atgtctaaac gattatagct
    14581 ggatactaag agaaatcaaa aaagcactaa gggagaacgt cccaaagtgc ttaatatcaa
    14641 ggcctcaaag cctgtcttat tcaataaaat attacaacat cttgttgtag aattcaacga
    14701 caagtgcttc gttgatttct gggttgattt cgtcgcgttc tggcaagcga gtcaatgaac
    14761 cttccaattt ttcagcgtcg aatgatacga atgctggacg tccaagagta gcttctactg
    14821 cttcaaggat tgctggaact ttcaatgatt tttcacgaac tgagatcact tgacctggag
    14881 ttacgcggta tgatgggata tcaacgcgtt tcccgtcaac aaggatgtga ccgtggttta
    14941 cgaattgacg agcttgacga cgagtagtcg cgagaccaag acggtaaaca acgttatcca
    15001 aacgacgttc caaaagaagc ataaagttga aacctaggat tccgcctttg atttttgtag
    15061 cttgtacgaa caagttacgg aattgttttt cacctacacc gtaagtgaaa cgaagttttt
    15121 gtttttcagc caattgcaaa ccgtattctg acaatttaga acggttgttt ggtccgtgtt
    15181 gtcctggtac gtagttacga cgtgccaatt ctttacctgt acctgtaagt gaaaggccaa
    15241 ggcgacgagc ttgtttccaa gatggtcctg tataacgtga catatgaatg tcctcctgat
    15301 ataaataata tttcggtgga aatagtcact tagaaagccc tgattcgtgc agatgccctt
    15361 cgcctaaaca gccaaggtta cttgtcataa gacacctgtt gacgagcttc atgctttcct
    15421 gctgatattt cacacaaaat ccattttacc atgaatagct ggatttgtaa aggggtttta
    15481 ggctttattt tcactaccag agagattgag aacgagggta aaggtacttc ctagaccgta
    15541 ctggctgctg actgtgattt ccccacccaa ttgatgggcc aattcacgcg caatcgcaag
    15601 tcctaatcca tgaccacctg tcttcatgtt acgcgaagtt tcgacacgat aaaggcgttt
    15661 gaaaatattt tccaaatcct ctggggcaat gccctgccct tcatcggtca cactgattga
    15721 aagctggccc ttctccagct tagtcaccac ttccagcttg gttcctggag cagaatattt
    15781 aaaagcgtta tcgaccagat tcaccaagat acgagaaagc ttagcataat ctccctcaat
    15841 ccgggcagac tctgggatta cctgcaagtg gacatctctt ctctcctgct caatcaaaaa
    15901 ctgaaattca ctcatgcact caattaagag cttgtccaga aaaatactgt ctttactggt
    15961 agtttccacc tgatttctag ctgtgtttag ggtcaaaaaa ttcaactcct caaccagttt
    16021 attgagcctc tccgtctggc gtccaatggt tgctagataa tgagcttgct ccgactcctt
    16081 gataatccca tccaaaatcc cttctaccgt cgcttggatc gaagtgatag gggtcttaat
    16141 atcatgcgac aactgggcaa tcatcaagcc cttttctcgt tcgctttctt ccaaggaatc
    16201 aaagcttacc tgcaaatcat gggacatctc attaaaagtt tgccctaatt gctgaaattc
    16261 tacaggacct tgaacctcca aatttgaagg aaaatccttg gccgctaccc gcttggcatg
    16321 ctccttgagt ttgcccaacg acgtaaagac tggcaatagg agaaagagac taatcccagc
    16381 accgacaagg ctggcaacga tggtcatccc aagcaaaaag taaatctcgc ctttcgcaat
    16441 cagcattttt tgaacagccc aaaaaacaac caaaatggtt aagagggttg aaataatata
    16501 tccaaccaaa atataacttt ttagtttcat gtttgtcctc tcggtttctc tatcttatat
    16561 cccaaccccc aaactgtctt aatagtgggc gtttggtcac tactatattt tgccagctcc
    16621 tgtcgaagag catggatatg cacattcaag gtattggtgt catccacgta gtcttctttc
    16681 cagatctttt catagaggtc tgtcttggag aaaactcgct ctggattgct agctaaaatc
    16741 cacagcaatt caaatgattt aacagttaaa tccagcattt cttctcctat ttgaacttca
    16801 tgactactat gattcatttt tagattgcca agggaaatca gctctgtttc gcccccacga
    16861 tgaaggcggc gcaaaatatt gtggacacgc aaaaccagct cacgtgggct aaaaggctta
    16921 gcaataaaat catctgctcc caagctcagg ccgtaaatct tgtcctgttc actggtctta
    16981 gcagtaataa ataggaaagg ctgctctggt gataagtatt gaacctcact gattaaatca
    17041 taaccatcca tccgaggcat cataacatct gtgataatca aatcaatcgg ttttttcttg
    17101 aacagctcta gcgcttccag tccatcatgg gctaccaaga cctgataacc tgcctgaatt
    17161 aagtatctct gatgaatatc tgtgatttct acctcgtcgt caacgagtaa aattgtcttt
    17221 cccatctgtc tctcctttga taaaaacagt gctatactgc tttaagtata acactatttt
    17281 tattgtttta cgatgatttt aatctgctat tgaaagaaag tcctgattgc tgattgagtt
    17341 gttaaactaa tcttagtcag cccactatcc atcatttatt tccttagctg attagttttc
    17401 ttcttttttg tttttcaaac ctagaccacc gagtaaacct gcaagcgcaa gcccaaggaa
    17461 accaatactt gccattgatg tttgagtctc accagtattt ggtagcatag ctttatcctc
    17521 tgacatcatc gtatcagaca tcttgttagc agaagcagcc atgttttcac ctgccatcgt
    17581 gttggtagaa cttgtcatgg tgtcagcagg catgctatct gtagtacctg tagcatgatt
    17641 gtgattcatc ggagtcacgc cagaaccaga gttagaaggt gataatgaac catttgctgt
    17701 gtctgatgtt tctttaac
//
LOCUS       DAVBEO010000047        17282 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 009
            SAMEA1678075-rid20185393.denovo.047, whole genome shotgun sequence.
ACCESSION   DAVBEO010000047 DAVBEO010000000
VERSION     DAVBEO010000047.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678075
            Sequence Read Archive: ERR226392
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 17282)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17282)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980207.1
            Genome Coverage       :: 150x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:50:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 72 of 147
            Pseudo Genes (incomplete)         :: 72 of 147
            Pseudo Genes (internal stop)      :: 42 of 147
            Pseudo Genes (multiple problems)  :: 32 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17282
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678075-rid20185393.denovo.047"
                     /strain="KS 009"
                     /db_xref="taxon:1313"
     gene            complement(<1..692)
                     /locus_tag="VQ543_001641"
     CDS             complement(<1..692)
                     /locus_tag="VQ543_001641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001021424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MucBP domain-containing protein"
                     /protein_id="HET2612331.1"
                     /translation="MNIILIAKPLRENTNTKANALNNGWARSGSEEFKKFSHFVGVDK
                     GIVRTNVLTGKKLSDKIRKEVGSGDSKLGKGGYFSTGDVLLGKDVVSYTVQVFSENNE
                     RVGVNTQSYRVQYNLPILADFSVIQDTVEPSRTVVEKIIPKLNIPEEEKGKITEEIKK
                     KKKTSELAELISENVKVRYVDEQGRLLSLKNDTGIGEKESDGTYITNKKQLIGTSYNV
                     TDKKLSSMTTTDG"
     gene            complement(803..1057)
                     /locus_tag="VQ543_001642"
     CDS             complement(803..1057)
                     /locus_tag="VQ543_001642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2612332.1"
                     /translation="MLNVDQDFMSISKSNKSGSDWKKTFTVRITNRLANDLNNVLKQV
                     DKDTPNTPTWLNSAASKAKDDDRVYKLLKTLIPGENYLSC"
     gene            complement(1415..1948)
                     /locus_tag="VQ543_001643"
     CDS             complement(1415..1948)
                     /locus_tag="VQ543_001643"
                     /inference="COORDINATES: protein motif:HMM:NF024751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
                     /protein_id="HET2612333.1"
                     /translation="MTIFKEQESEKVAEFLDILDNLKDLPIVYIDETGIDRYLYRPYA
                     GAPRGEKVYEKISGRRFERTSIVAGQVDGEFIAPMIYKKSMTSDFFVEWFKTQLLPAL
                     KTPHVIVMGNASFHPKNILDELCIQDKHFFLPLPPYSPDLNPIEQAWAILKKKVTDLL
                     REVPTIFECLECFFKTR"
     gene            complement(1935..2261)
                     /locus_tag="VQ543_001644"
     CDS             complement(1935..2261)
                     /locus_tag="VQ543_001644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET2612334.1"
                     /translation="MAYNTDFKQGALDSIKGGHRHVEAAKVFWCWRQNSLHVGKERRE
                     QRNLERKKRVVKKRKIPLEELKAFVEAHPDAFLREIAAHFDCAVPSVWAALKQIKVTL
                     KKDDDL"
     gene            2495..4213
                     /locus_tag="VQ543_001645"
     CDS             2495..4213
                     /locus_tag="VQ543_001645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HET2612335.1"
                     /translation="MSYQENYQKWVDFVELPDYLRQDLENMDEKTKEDAFYTNLEFGT
                     AGMRGLVGAGTNRINIYVVRQATEGLARLIESKGGNEKERGVAIAYDSRHFSPEFAFE
                     SAAVLAKHGIKSYVFESLRPTPELSFAVRHLNCFAGIMVTASHNPAPFNGYKVYGEDG
                     GQMPPHDADALTTYIRAIENPFAVEVADVETEKASGLIEVIGEAVDVEYLKEVKDVNI
                     NPALIEEFGKDMKIVYTPLHGTGEMLARRALAQAGFDSVQVVEAQATADPDFSTVTSP
                     NPESQAAFALAEELGRQVGADVLVATDPDADRVGVEVLQKDGSYLNLSGNQIGAIMAK
                     YILEAHKNAGTLPENAALCKSIVSTDLVTKIAESYGATMFNVLTGFKFIAEKIQEFEE
                     KHNHTYMMGFEESFGYLIKPFVRDKDAIQAVLVVAELAAYYRSRGLTLADGIEEIYKE
                     YGYYAEKTISVTLSGVDGAEQIKAIMAKFRNNAPKEWNATAITVVEDFKAQTATVADG
                     TVTNLTTPPSDVLKYTLADGSWIAVRPSGTEPKIKFYIAVVGETNEESQAKIANIEAE
                     INAFVK"
     gene            4324..4671
                     /locus_tag="VQ543_001646"
     CDS             4324..4671
                     /locus_tag="VQ543_001646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000434646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HET2612336.1"
                     /translation="MEQFLDNIKDLEVTTVVRAQEALDKKETATFFIGRKTCPYCRKF
                     AGTLSGVVAETKAHIYFINSEEPSQLNDLQAFRSRYGIPTVPGFVHITDGQINVRCDS
                     SMSAQEIKDFAGL"
     gene            complement(4949..5785)
                     /locus_tag="VQ543_001647"
     CDS             complement(4949..5785)
                     /locus_tag="VQ543_001647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HET2612337.1"
                     /translation="MKKWMLVLVSLMTALFLVACGKNSSETSGDNWSKYQSNKSITIG
                     FDSTFVPMGFAQKDGSYAGFDIDLATAVFEKYGITVNWQPIDWDLKEAELTKGTIDLI
                     WNGYSATDERREKVAFSNSYMKNEQVLVTKKSSGITTAKDMTGKTLGAQAGSSGYADF
                     EANPEILKNIVANKEANQYQTFNEALIDLKNDRIDGLLIDRVYANYYLEAEGVLNDYN
                     VFTVGLETEAFAVGARKEDTTLVKKINEAFSSLYKDGKFQEISQKWFGEDVATKEVKE
                     GQ"
     gene            complement(5798..6427)
                     /locus_tag="VQ543_001648"
     CDS             complement(5798..6427)
                     /locus_tag="VQ543_001648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000891751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HET2612338.1"
                     /translation="MLELRNINKVFGDKQILSNFSLSIPEKQILAIVGPSGGGKTTLL
                     RMLAGLETIDSGQIFYNGQPLELDELQKRNLLGFVFQDFQLFPHLSVLDNLTLSPVKT
                     MGMKQEEAEKKASGLLEQLGLGGHAEAYPFSLSGGQKQRVALARAMMIDPEIIGYDEP
                     TSALDPELRLEVEKLILQNRELGMTQIVVTHDLQFAENIADVLLKVEPK"
     gene            complement(6437..7078)
                     /locus_tag="VQ543_001649"
     CDS             complement(6437..7078)
                     /locus_tag="VQ543_001649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004253193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HET2612339.1"
                     /translation="MSYLFEILPSLLNGASTTVQVFALVLLFSIPLGVLIAFALQVHW
                     KPLHYLINIYIWVMRGTPLLLQLIFIYYVLPSIGIRLDRLPAAIIAFVLNYAAYFAEI
                     FRGGIDTIPRGQYEAAKVLKFSPFDRVRYIILPQVTKIVLPSVFNEVMSLVKDTSLVY
                     ALGISDLILASRTAANRDASLVPMFLAGAIYLILIGIVTIISKKVEKKYSYYR"
     gene            complement(7224..8453)
                     /locus_tag="VQ543_001650"
     CDS             complement(7224..8453)
                     /locus_tag="VQ543_001650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HET2612340.1"
                     /translation="MNNSQQMLQALEEQDLTKAEHYFAKALENDSSDLLYELATYLEG
                     IGFYPQAKEIYLKIVEDFPEVHLNLAAIASEDGQIEEAFTYLEEIQADSDWYVSSLAL
                     KADLYQLEGLTDVAREKLLEALTYSEDSLLILGLAELDSELENYQAAIQAYAQLDNRS
                     IYEQTGISTYQRIGFAYAQLGKFETATEFLEKALELEYDDLTAFELASLYFDQEEYQK
                     ATLYFKQLDTISPDFEGYEYGYSQALHKEHQVQEALRIAKQGLEKNPFETRLLLAASQ
                     FSYELHDASGAENYLLTAKEDAEDTEEILLRLATIYLEQERYEDILDLQSEESENLLT
                     KWMIARSYQEMDDLDTAYEHYQELIGDLKDNPEFLEHYIYLLRELGHFEEAKVHAHTY
                     LKLVPDDVQMQELFERL"
     gene            complement(8443..9609)
                     /locus_tag="VQ543_001651"
     CDS             complement(8443..9609)
                     /locus_tag="VQ543_001651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000435446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HET2612341.1"
                     /translation="MEQKEKHFSLSWFFKWFLDNKAITVFLVTLLLGLNLFILSKISF
                     LFSPVLDFLAVVMLPVILSGLLYYLLNPIVDWMEKHKVNRVIAITIVFVIIALFIIWG
                     LAVAIPNLQRQVLTFARNVPVYLEDIDRIVNGLVAQHLPDDFRPQLEQVLTNFSSQAT
                     VLASKVSSQAVNWVSAFISGASQVIVALIIVPFMLFYLLRDGKGLRNYLTQFIPRKLK
                     EPVGQVLSDVNQQLSNYVRGQVTVAIIVAVMFIIFFKIIGLRYAVTLGVTAGILNLVP
                     YLGSFLAMLPALVLGLIAGPVMLLKVVIVFIVEQTIEGRFVSPLILGSQLNIHPINVL
                     FVLLTSGSMFGIWGVLLGIPVYASAKVVISAIFEWYKVVSGLYELEGEEVKSEQ"
     gene            9753..10766
                     /locus_tag="VQ543_001652"
     CDS             9753..10766
                     /locus_tag="VQ543_001652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000665618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactonase family protein"
                     /protein_id="HET2612342.1"
                     /translation="MKETVYFGTYTRRTSQGIYKADFDTETGQLSNLELFAAEPSPTY
                     LAFDQHQHLYTVGSQDDKGGIAAYQTDGTVLNHVVEEGAPHCYVAVDEKRDLVYAANY
                     HKGQVLVYKRQEDGSLLLSDMDQHSGQGPHENQASPHVHYTDLTPDHYLVTCDLGTDQ
                     VITYDLDQEGKLSKLYTYHSKPGAGSRHIIFHNHYKIAYLICELNSTIEVLIYDGVGE
                     FERMQVISTLPEAYEGFNGTAAIHLSKDGKYLYASNRGHDSIAVYTILADGSLELLEI
                     VPTHGQTPRDFDLTPDQKFLIVVHQDSDNATVFKRNCDNGRLAELSNDFHVPEAVCIR
                     FAP"
     gene            complement(10811..11230)
                     /locus_tag="VQ543_001653"
     CDS             complement(10811..11230)
                     /locus_tag="VQ543_001653"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit epsilon"
                     /protein_id="HET2612343.1"
                     /translation="MAQLTVQIVTPDGLVYDHHASYVSVRTLDGEMGILPRHENMIAV
                     LAVDEVKVKRIDDKDQVNWIAVNGGVIEIANDMITIVADSAERARDIDISRAERAKLR
                     AERAIEEAQDKHLIDQERRAKIALQRAINRINVGNRL"
     gene            complement(11241..12647)
                     /gene="atpD"
                     /locus_tag="VQ543_001654"
     CDS             complement(11241..12647)
                     /gene="atpD"
                     /locus_tag="VQ543_001654"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit beta"
                     /protein_id="HET2612344.1"
                     /translation="MSSGKIAQVIGPVVDVLFAAGEKLPEINNALVVYKNDERKTKIV
                     LEVALELGDGMVRTIAMESTDGLTRGMEVLDTGRPISVPVGKETLGRVFNVLGDTIDL
                     EAPFTEDAERQPIHKKAPTFDELSTSSEILETGIKVIDLLAPYLKGGKVGLFGGAGVG
                     KTVLIQELIHNIAQEHGGISVFAGVGERTREGNDLYWEMKESGVIEKTAMVFGQMNEP
                     PGARMRVALTGLTIAEYFRDVEGQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQP
                     TLATEMGQLQERITSTKKGSVTSIQAIYVPADDYTDPAPATAFAHLDSTTNLERKLVQ
                     LGIYPAVDPLASSSRALAPEIVGEEHYAVAAEVKRVLQRYHELQDIIAILGMDELSDE
                     EKTLVARARRIQFFLSQNFNVAEQFTGQPGSYVPVAETVRGFKEILDGKYDHLPEDAF
                     RGVGSIEDVIAKAEKMGF"
     gene            complement(12733..13611)
                     /locus_tag="VQ543_001655"
     CDS             complement(12733..13611)
                     /locus_tag="VQ543_001655"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002895995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit gamma"
                     /protein_id="HET2612345.1"
                     /translation="MAVSLNDIKTKIASTKNTSQITNAMQMVSAAKLGRSEEAARNFQ
                     VYAQKVRKLLTDILHGNGAGASTNPMLISRSVKKTGYIVITSDRGLVGGYNSSILKAV
                     MELKEEYHPDGKGFEMICIGGMGADFFKARGIQPLYELRGLADQPSFDQVRKIISKTV
                     EMYQNELFDELYVCYNHHVNTLTSQMRVEQMLPIVDLDPNEADEEYSLTFELETSREE
                     ILEQLLPQFAESMIYGAIIDAKTAENAAGMTAMQTATDNAKKVINDLTIQYNRARQAA
                     ITQEITEIVAGASALE"
     gene            complement(13627..15132)
                     /locus_tag="VQ543_001656"
     CDS             complement(13627..15132)
                     /locus_tag="VQ543_001656"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit alpha"
                     /protein_id="HET2612346.1"
                     /translation="MAINAQEISALIKQQIENFKPNFDVTETGVVTYIGDGIARAHGL
                     ENVMSGELLNFENGSYGMAQNLESTDVGIIILGDFTDIREGDTIRRTGKIMEVPVGES
                     LIGRVVDPLGRPVDGLGEIHTDKTRPVEAPAPGVMQRKSVSEPLQTGLKAIDALVPIG
                     RGQRELIIGDRQTGKTTIAIDTILNQKDQDMICIYVAIGQKESTVRTQVETLRQYGAL
                     DYTIVVTASASQPSPLLFLAPYTGVAMAEEFMYQGKHVLIVYDDLSKQAVAYRELSLL
                     LRRPPGREAFPGDVFYLHSRLLERSAKVSDELGGGSITALPFIETQAGDISAYIATNV
                     ISITDGQIFLGDGLFNAGIRPAIDAGSSVSRVGGSAQIKAMKKVAGTLRIDLASYREL
                     EAFTKFGSDLDAATQAKLNRGRRTVEVLKQPVHKPLPVEKQVTILYALIHGFLDTVPV
                     DDIVRFEEEFHAFFDAQHPEILETIRDTKDLPEEAVLDAAITEFLNQSSFQ"
     gene            complement(15147..15683)
                     /locus_tag="VQ543_001657"
     CDS             complement(15147..15683)
                     /locus_tag="VQ543_001657"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit delta"
                     /protein_id="HET2612347.1"
                     /translation="MDKKTVKVIEKYSMPFVQLVLEKGEEDRIFSDLTQIKQVVEKTG
                     LPSFLKQVAVDESDKEKTIAFFQDSVSPLLQNFIQVLAYNHRANLFYDVLVDCLNRLE
                     KETNRFEVTITSAHPLTDEQKTRLLPLIEKKMSLKVRSVKEQIDESLIGGFVIFANHK
                     TIDVSIKQQLKVVKENLK"
     gene            complement(15683..16177)
                     /gene="atpF"
                     /locus_tag="VQ543_001658"
     CDS             complement(15683..16177)
                     /gene="atpF"
                     /locus_tag="VQ543_001658"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit B"
                     /protein_id="HET2612348.1"
                     /translation="MHVTVGELIGNFILITGSFILLLVLIKKFAWSNITGIFEERAEK
                     IASDIDRAEEARQKAEVLAQKREDELAGSRKEAKTIIENAKETAEQSKANILADAKLE
                     AGHLKEKANQEIAQNKVEALQSVKGEVADLTISLAGKIISQNLDSHAHKALIDQYIDQ
                     LGEA"
     gene            complement(16191..16907)
                     /gene="atpB"
                     /locus_tag="VQ543_001659"
     CDS             complement(16191..16907)
                     /gene="atpB"
                     /locus_tag="VQ543_001659"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit A"
                     /protein_id="HET2612349.1"
                     /translation="MEESINPIISIGPVIFNLTMLAMTLLIVGVIFVFIYWASRNMTL
                     KPKGKQNVLEYVYDFVIGFTEPNIGSRYMKDYSLFFLCLFLFMVIANNLGLMTKLQTI
                     DGTNWWSSPTANLQYDLTLSFLVILLTHIESVRRRGFKKSIKSFMSPVFVIPMNILEE
                     FTNFLSLALRIFGNIFAGEVMTSLLLLLSHQAIYWYPVAFGANLAWTAFSVFISCIQA
                     YVFTLLTSVYLGNKINIEEE"
     gene            complement(16942..17142)
                     /locus_tag="VQ543_001660"
     CDS             complement(16942..17142)
                     /locus_tag="VQ543_001660"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015545704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit C"
                     /protein_id="HET2612350.1"
                     /translation="MNLTFLGLCIACMGVSVGEGLLMNGLFKSVARQPDMLSEFRSLM
                     FLGVAFIEGTFFVTLVFSFIIK"
BASE COUNT         5222 a         3786 c         3096 g         5178 t
ORIGIN      
        1 ccgtcagtag tagtcatgct actgagtttt ttatctgtga cattgtagct ggtaccaatc
       61 agttgttttt tattggtaat gtaggttccg tcactttctt tttctccaat tccagtatca
      121 tttttcaatg atagcaaacg cccttgttca tcaacatagc gaactttcac attttctgag
      181 attagttctg ccaattctga ggtttttttc tttttcttga tttcttcggt tattttccct
      241 ttctcttctt cgggaatatt tagttttgga atgatttttt caacaacggt tcgtgatggt
      301 tccacagtat cttggatgac tgaaaagtca gctagaattg ggagattata ctgaacacgg
      361 taactttgag tgtttactcc tactctttca ttattctctg aaaatacttg tacggtataa
      421 gaaacaacat cttttcctaa tagaacatcc ccagtagaga aatagccgcc ttttcctagt
      481 ttgctatctc cagagcccac ttctttccta attttatcag atagtttttt accagtcagt
      541 acattcgttc gcacaatccc tttgtctacc cctacaaagt gggagaactt tttgaactct
      601 tcagaaccag atctagccca accattatta agggcatttg cttttgtatt tgtattctct
      661 ctcaaaggtt tggcgattag aattatattc atcggcactt agagttgctg ctatatctga
      721 ctcttgaata ccaacttcct tactaccatt tctagcggca gtatatgtgt atttatctgt
      781 ttctacttct agctgattat ccttaacatg ataggtaatt ttctcctggt ataagagtct
      841 tcagtagttt atatactctg tcatcatctt tagctttaga agcagctgag tttagccaag
      901 ttggggtatt aggagtatct ttatcaacct gtttcaagac attattcaag tcatttgcta
      961 gcctattggt tatcctcact gtgaaagttt tcttccagtc tgaaccactt ttattagact
     1021 tagatatgct catgaaatcc tggtcaacat tcaacacaat atcgccttgt tttttagcat
     1081 cttccgttgc ttctgcttca aattgatcat ggagtttttg ttgctctggt gtatagtttt
     1141 tttatttaca cgatttaatg tactattttt tattttagta ttaagaactc cattaatacg
     1201 atttttaaac tctgcttcaa aaaatccctt aatttgttgg tgcgcaagtt caacattcaa
     1261 acctttctta tacaagtctt cattctgata caagtcttca ttctgaacga tttcggctac
     1321 acggtgaatg gtttgatcgt ataccgtctt ctcttaacca gcagtatcct tagttttaat
     1381 gactactcga taggttcctt tagaaccgtt atagtcatct agttttaaaa aagcattcca
     1441 aacattcaaa aatagttgga acttccctta ataaatccgt cactttcttt ttcaagatag
     1501 cccaagcttg ctcaatagga ttcaaatccg gtgaataagg tggtagaggt aagaaaaagt
     1561 gtttatcttg gatgcagagt tcatccaaaa tgttcttggg atgaaaacta gcattgccca
     1621 tgacaataac atgaggtgtc ttcaaagcag gtaggagttg cgttttgaac cactccacaa
     1681 agaaatcgct tgtcatgctt ttcttgtaaa tcatgggagc tataaactct ccgtctactt
     1741 gtcctgcaac aattgaagtt cgctcaaaac gacgtccgct aatcttttca tagactttct
     1801 cccctctagg agcccctgca taaggacgat agaggtagcg gtcgattcct gtttcatcaa
     1861 tatatacgat tggtaaatct tttaggttat ccaaaatatc aagaaactca gcgactttct
     1921 ctgactcttg ttccttaaag atcgtcatct ttttttaaag tgaccttaat ctgctttaaa
     1981 gctgcccata ctgaaggaac agcacaatca aaatgtgccg caatttcccg taaaaaagca
     2041 tctggatgag cctctacaaa ggctttcaat tcttctaaag ggatcttacg ctttttgacg
     2101 actcgctttt tccgctctaa gttcctttgt tcacgtcttt cttttcccac gtgaagagag
     2161 ttctgacgcc aacaccaaaa aactttggcc gcctcgacat gtctgtgccc tcctttgatg
     2221 gaatctaatg ctccttgttt aaaatcagta ttatatgcca tagctttatt agaccatgct
     2281 tattttaaac taagcaacta tatcaatgtt ttgttatgag aagacttact ttttttactg
     2341 aaattgaatt tttcctagcc tcaacatcat ataaccccaa aattcaatct gacctggttt
     2401 gaagagatgt tcgaagcaga taaggtttta ctaaaactaa aaaaaatgat ataatcaaac
     2461 tgattaaatg ttttaaaaat aaaggagaat ttgaatgtct taccaagaaa attaccagaa
     2521 atgggttgat tttgtggagc ttcctgacta ccttcgtcaa gatttggaaa atatggacga
     2581 aaaaactaag gaagatgcct tctatacaaa tcttgaattt ggtactgcag gtatgcgtgg
     2641 cttggttggt gctggtacaa accgtatcaa catctacgtt gttcgccaag ctactgaagg
     2701 attggctcgt ttgattgagt caaaaggtgg aaacgagaaa gaacgcggtg tagcaattgc
     2761 ctacgatagc cgtcacttct cacctgagtt tgcctttgaa tctgcggcag ttcttgctaa
     2821 acacggcatc aaatcttacg tatttgaaag ccttcgtccg actccagaac tatcatttgc
     2881 agttcgtcat ctcaactgtt tcgcaggtat catggtcaca gccagccaca accctgctcc
     2941 atttaacggt tacaaggttt acggtgaaga cggtggacaa atgcctccac acgatgcgga
     3001 cgctttgact acttatatcc gtgcaatcga aaacccattt gcagttgaag ttgctgatgt
     3061 ggaaactgaa aaagcttctg gcttgattga agttatcggc gaagctgttg acgtagaata
     3121 ccttaaagag gttaaggacg taaacatcaa cccagccttg attgaagaat ttggtaaaga
     3181 catgaagatt gtctacacac cacttcatgg tactggtgaa atgttggctc gtcgtgctct
     3241 tgcccaagca ggatttgact ctgttcaagt tgttgaagcg caagcaactg ctgacccaga
     3301 cttctcaact gtaacatctc caaacccaga aagccaagca gcctttgccc ttgctgaaga
     3361 acttggtcgt caagttggtg cagatgttct tgtcgcaact gacccagacg ctgaccgtgt
     3421 tggtgttgaa gttcttcaaa aagatggtag ctacctcaac ctttcaggta accaaatcgg
     3481 tgctatcatg gctaaataca tcttggaagc tcacaaaaac gctggaactc ttcctgaaaa
     3541 tgccgctctc tgcaaatcta tcgtttcaac tgacttggta acgaagattg ctgaaagcta
     3601 cggcgcaact atgttcaacg tcttgacagg tttcaaattt atcgctgaaa aaatccaaga
     3661 attcgaagaa aaacacaacc acacttacat gatgggattt gaagaaagct tcggttactt
     3721 gattaaacca tttgtacgtg ataaagatgc catccaagcc gttcttgtcg ttgctgaact
     3781 tgctgcctac taccgttctc gtggtttgac acttgctgac ggtatcgaag aaatctataa
     3841 agaatatggc tactacgcag aaaaaacaat ctctgttact ctttcaggtg tcgatggtgc
     3901 tgaacaaatc aaagcgatta tggctaaatt ccgcaacaat gctccaaaag aatggaacgc
     3961 aacagctatc actgtcgtag aagacttcaa ggcacaaact gctactgttg ctgacggtac
     4021 tgttacaaac ttgacaactc ctccaagtga tgtgttgaaa tacacacttg ctgacggttc
     4081 atggattgcc gttcgccctt caggtacaga accaaaaatc aagttctaca ttgcagttgt
     4141 aggagaaacc aacgaagaat cacaagctaa gattgctaac atcgaagcag aaatcaatgc
     4201 atttgtaaaa taaagaccta taaaagatga gaccaaccaa cctcatcttt tttcgtatca
     4261 aatctaagca attttagaaa ctttatggca tactagactt atcaatgaaa gcgaggtaat
     4321 ctcatggaac aatttttaga taacatcaaa gaccttgaag tcactacagt tgtgcgtgcg
     4381 caagaagctc ttgataaaaa agaaactgca accttcttta tcggtcgcaa aacttgccct
     4441 tactgccgta aatttgcagg tacattgtca ggtgtcgtag ctgaaaccaa agctcacatt
     4501 tacttcatca atagtgaaga accaagccaa ctcaatgatt tgcaagcatt ccgctcacgc
     4561 tatggaatcc caactgtacc aggttttgtt catattacag atggacaaat caacgtccgt
     4621 tgcgactctt caatgtcagc acaagaaatc aaagatttcg caggattgta aaaaatcagc
     4681 taacaagtct taaaatcaca aaaacgcata atgtaaggtg caaaaacctt gatattatgc
     4741 gttttattgt tcctaaaaca gttacatcag catttcatta cagaacattt taattttgga
     4801 agtcaaatca atttttaaca atgttttaga aatcacagtg ggctattcca tattaaatta
     4861 tccagattca atcgctatta tcgttttcct agattacaaa aaaactgcgt tttgctaatc
     4921 aaaacgtagt ctcagccact attttatctt actgtccttc ttttacttct ttggttgcta
     4981 catcttctcc aaaccatttt tggctgattt cttggaactt gccgtccttg taaagactag
     5041 aaaaagcttc atttatcttc ttaaccaagg ttgtatcttc cttacgggct ccaaccgcaa
     5101 aagcttctgt ttctagtcca actgtaaaga cattataatc gtttaaaaca ccttctgctt
     5161 ctaaataata gtttgcatag acacggtcaa tcaatagacc atcaattcga tcgtttttca
     5221 aatcaatcaa ggcttcatta aaggtttggt attgattcgc ttccttatta gcgacaatat
     5281 tcttcaaaat ttctggattt gcttcaaagt ccgcataacc agatgaacca gcttgagctc
     5341 ctaatgtctt tccagtcata tcctttgcag tcgtgatacc agatgatttc ttcgtaacca
     5401 atacctgctc attcttcata tatgagttac tgaaagccac cttttcacgg cgttcgtctg
     5461 tagcggaata gccattccaa atcagatcaa tcgttccttt tgtcaattca gcttctttca
     5521 aatcccaatc aatcggttgc caatttaccg tgattccgta tttttcaaaa acagctgtag
     5581 ctaaatcaat atcaaatcct gcataagaac catctttctg agcaaatccc attggaacaa
     5641 aagtactatc aaatccaata gtaatagact tgttagactg gtactttgac caattatctc
     5701 cactagtttc gctagaattt ttcccacaag ctactaagaa caaagcagtc atcagactga
     5761 ctaatacaag catccatttt ttcatccatt tttcctccta tttaggttct actttcaata
     5821 atacatctgc gatattttca gcaaactgca aatcatgggt aaccacaatc tgggtcatcc
     5881 caagttccct attttgcaag attagcttct ccacttccaa acgtaattct ggatccaggg
     5941 cagaagttgg ttcatcgtag ccaatgattt ctgggtcaat catcatagca cgcgccaaag
     6001 ccacccgctg cttttgccca ccagatagtg agaaaggata ggcctctgcg tgtcctccta
     6061 gtcctaactg ttccaagagt ccactcgcct tcttctcagc ctcttcctgc ttcattccca
     6121 tggtcttcac aggcgataag gtcaaattgt ccagaactga taaatgaggg aacagttgaa
     6181 aatcttggaa tacaaatccc agtagattgc gcttctgcaa ttcatccagc tctaaaggtt
     6241 gtccattata aaagatttgc cctgaatcaa tggtttcaag acctgcaagc atacgtaaaa
     6301 gagttgtctt acctccacca gaaggtccaa cgatagccag gatttgcttt tcaggaatac
     6361 ttagactgaa attagacagg atttgtttgt ctccaaagac tttattgata tttcgtaatt
     6421 ctaacatggc agcctcctat ctataataac tatacttctt ctcaactttt ttggaaataa
     6481 ttgtcacaat cccaatcaaa atcaaataaa tggctcctgc caagaacata ggaactagac
     6541 tagcatcgcg gttagcagct gttcgactag ccaagataag gtctgaaatt ccgagagcat
     6601 agaccaaaga agtatccttg accaaactca taacttcatt aaagacacta ggaagaacga
     6661 tcttggtcac ttggggcaag ataatatagc gcactctgtc aaaagggcta aacttcaaga
     6721 ccttggcggc ctcatactgt cctcttggaa tagtgtcaat tcccccacgg aaaatttctg
     6781 caaagtaagc tgcatagttg agaacaaagg caataatagc tgcaggaagg cggtctaaac
     6841 gaatcccaat acttgggagc acataataga taaaaatcag ttgcaagagt aagggggttc
     6901 ctcgcataac ccagatgtaa atgttaatca gataatggag gggcttccaa tggacttgca
     6961 aggcaaaggc aatcaaaacg cccaagggaa tcgaaaatag caagaccagt gcaaagacct
     7021 gtacagtcgt gctcgcacca ttcagtaaac tcggtaatat ctcaaataaa taagacatac
     7081 tgcacctcct aaaagtaatt gttcctatta tagcatgaat aaacaagatt accaagtatt
     7141 tttgtaaaaa gattctacca tatacaaata aaaaccgtag ctatcaaaag agataaacta
     7201 cagttctata tgtttaaaca ttcttacaat ctctcaaaca gttcttgcat ttgcacatca
     7261 tctggaacca gttttaagta agtgtgagca tggacttttg cttcttcaaa atgtcccaat
     7321 tcacgcaaga gatagatata gtgttccaga aattctggat tgtccttcaa atctcctatc
     7381 aactcttgat aatgctcata agcagtatcc aaatcgtcca tttcttgata agaacgagca
     7441 atcatccact tggtcaaaag attttctgac tcctcactct gcaagtctag aatatcctca
     7501 taacgctcct gctccagata aatagtggct aaacgaagca agatttcttc tgtatcctca
     7561 gcgtcttctt ttgcagtaag gagataattt tctgcaccac tagcatcatg caattcataa
     7621 gaaaattgtg aagcagctag caagaggcga gtttcaaagg gatttttctc taatccttgc
     7681 ttagcgatac gcagggcttc ttgaacttga tgttccttat gtaaagcctg actgtaccca
     7741 tactcatagc cttcaaagtc aggagaaatg gtatcaagct gcttaaagta gagggtggct
     7801 ttttgatatt cttcttgatc aaaataaaga ctggccaact caaaagctgt taagtcatcg
     7861 tattctaact ccagggcttt ttctaaaaac tcagtagccg tttcaaattt ccctaactga
     7921 gcataggcaa agccaattcg ttgataggtg gaaatgcccg tttgctcata aatcgagcga
     7981 ttatctaact gggcataggc ttgaatagcc gcttggtaat tttccaactc actatccaac
     8041 tctgccaaac ccaatatcaa gagagaatcc tctgagtagg tcaaggcctc caataatttc
     8101 tcacgtgcca catctgtcaa accttccagc tggtaaaggt ctgccttcag agccaaagac
     8161 gagacatacc agtcactgtc agcttggatt tcctcaagat aggtaaaggc ttcttctatt
     8221 tgaccatcct cgctagcaat tgcagctaga ttaagatgaa cctctggaaa atcctctaca
     8281 attttcaggt aaatttcctt ggcctgagga tagaaaccaa tcccttcaag ataagttgcc
     8341 aactcataca gaagatcact tgaatcattt tctaaagctt tggcgaaata atgctcagcc
     8401 ttagttaaat cttgctcctc caaagcctgt aacatctgtt gactattgtt cactcttgac
     8461 ttcctcaccc tctaattcat atagaccact gactacctta taccattcga aaatggctga
     8521 aatgacaacc ttagcagagg cataaaccgg aataccaagt aaaactcccc agataccaaa
     8581 catagatcct gaagttaaca aaacaaagag aacattaata gggtggatgt ttaattgact
     8641 tcccaaaatc aatggagaga caaaacggcc ttcaatagtt tgttctacga taaagacaat
     8701 cactactttc aaaagcatga ctggaccagc aatcaaaccc aatactagag caggaagcat
     8761 ggctagaaag ctaccaagat aagggaccag atttaaaata ccagcagtaa cccccagcgt
     8821 aaccgcatag cgtagaccaa taatcttgaa gaagatgata aacattactg ctacaataat
     8881 agccactgtc acttgccctc gaacatagtt ggacaactgt tgattcacat ctgataaaac
     8941 ttgtccaaca ggttccttca attttcttgg aatgaattgg gtcaaatagt tacgcaagcc
     9001 tttcccatca cgcaagagat aaaagagcat gaaaggaacg ataatcaagg caacaatcac
     9061 ttgagaagct ccgctaataa aggcactcac ccagttgact gcctgagatg aaaccttact
     9121 tgccaaaact gtagcctggc tagaaaaatt ggtcaaaact tgctctaatt gaggtctgaa
     9181 atcatctggc aggtgctggg ctaccaatcc attaacaatc ctatctatat cttctaagta
     9241 aacaggaacg tttcttgcaa aggtcaaaac ctgacgttgc agatttggaa tggcgactgc
     9301 caagccccaa atgataaaga gagcgatgat aacaaagaca atagtgatag ctataacacg
     9361 attaacctta tgcttctcca tccaatcaac aataggattc aacaaataat ataacaaacc
     9421 agacaaaatg actggcaaca tcacaactgc taaaaagtct aaaacaggtg aaaatagaaa
     9481 actaatctta cttaaaataa aaagattcag tcccaataat aaggttacta aaaataccgt
     9541 aattgccttg ttatctaaaa accacttgaa aaaccaagat aggctaaaat gtttctcttt
     9601 ttgctccata aatacttcct ttctattgtt ctctcattat accatttttg aaacaaaata
     9661 actctttttt aaagtgctta catctaattg gatatcttta atttacttgt ttttgtgata
     9721 taatagtctt atctttacac agaggtatag taatgaaaga aactgtttat tttggaactt
     9781 atacacgtcg tacttctcaa gggatttaca aggcagactt tgatacagaa actggtcagc
     9841 tttcaaatct agaacttttt gcagctgagc caagtccaac ctaccttgcc tttgaccagc
     9901 accaacattt atacactgtt ggtagccaag acgataaggg gggaattgca gcctatcaaa
     9961 ctgacgggac tgtgttaaat catgttgttg aagaaggagc tccccactgt tatgttgctg
    10021 tcgatgaaaa gcgtgatttg gtttacgcag ccaactatca caagggacaa gtccttgttt
    10081 ataaacgcca ggaagatggt agtcttctac ttagtgatat ggatcaacac agtggccaag
    10141 gtccacatga aaatcaagct tccccccatg ttcactatac agatttaaca cctgaccact
    10201 atctagtgac ctgcgacttg ggaactgacc aagtcatcac ctatgacctc gatcaagaag
    10261 gaaaattatc taagctctat acctatcaca gcaagccagg agcaggctca cgccatatca
    10321 ttttccataa ccactataaa atcgcttatc tcatttgtga actcaatagt actatcgaag
    10381 ttttaatcta cgatggcgtt ggcgaatttg aacgtatgca ggtcatttca actttaccgg
    10441 aagcttacga aggctttaat ggaaccgctg ctattcatct ctctaaagac ggtaaatacc
    10501 tctacgcttc taaccgtggc catgattcta tcgcagtata taccatcctt gcggacggta
    10561 gcttagagtt attagaaatc gttccaacgc atggtcagac tccacgtgat tttgatttga
    10621 cacccgacca aaaatttctc attgttgtcc atcaagactc tgacaatgca actgtcttta
    10681 aacgtaattg tgacaatggt cgtctagcag aactctccaa cgacttccat gttcccgaag
    10741 cagtctgcat ccgttttgct ccttaaaaca ccataaaaaa tgaacttggt attttcaagt
    10801 tcattttttc ttatagtcta tttccgacat taatacggtt aatagcacgt tgcaaagcaa
    10861 tcttagcacg acgttcttgg tcaatcaaat gtttgtcttg tgcttcttca attgcacgtt
    10921 ctgcacgaag tttggcacgt tctgcacgac tgatatcgat atcacgagca cgttctgcag
    10981 agtcagcgac gattgtgatc atatcattgg caatttcaat aacaccaccg tttactgcaa
    11041 tccagttcac ttgatcttta tcatcgatac gttttacctt tacttcatca actgctaaaa
    11101 ccgcaatcat attttcatgt cgtggcaaga tccccatctc accatccaga gttcgaaccg
    11161 atacatagct ggcatggtga tcatagacga gaccatctgg tgtcacgatc tggacagtta
    11221 actgagccat agttcacctc ttaaaatccc attttttcag cttttgcaat cacatcttcg
    11281 atagaaccta caccacggaa ggcatcttct ggcaagtggt cgtatttacc atcaaggatt
    11341 tccttaaagc cacgtacagt ttcagcaact ggaacataag aacctggctg accagtaaat
    11401 tgttccgcaa cattgaagtt ttgtgacaag aagaactgga tacgacgggc gcgagcaacc
    11461 aaggtctttt cttcatcaga aagttcatcc ataccaagga tagcaatgat atcttgcaat
    11521 tcatggtaac gttgaaggac acgttttact tcagcagcaa ctgcatagtg ctcttctcca
    11581 acgatttcag gtgccaaggc acgtgagctt gaagcaagtg ggtcaacggc tgggtagata
    11641 cccaattgta ccaacttacg ttccaagttt gttgttgaat ccaagtgagc gaaggctgtt
    11701 gctggcgctg ggtcagtata gtcatccgct ggcacataga tagcctggat agaggttaca
    11761 gaacccttct tggttgatgt gatacgttct tgcaattgac ccatttccgt agcaagtgtt
    11821 ggttggtaac caacggctga tggcatacga cccaaaaggg cagatacttc tgaaccagcc
    11881 tgagtgaaac ggaagatatt atcgataaag agaagcacgt cttggccttc cacatcacgg
    11941 aagtattcag cgattgtcaa accagtaagg gcaacacgca tacgtgctcc tggtggctca
    12001 ttcatctgac caaagaccat ggctgttttc tcgataacgc ctgattcttt catttcccag
    12061 taaaggtcat tcccctcacg agtacgttcc ccaacaccag caaatactga aataccaccg
    12121 tgctcttggg caatgttgtg aatcaattct tggattaaga cagttttacc aactccggca
    12181 ccaccgaaaa gtccaacttt accaccttta aggtaagggg caagaaggtc aataaccttg
    12241 atccctgttt caaggatttc agaagaggta gacaactcat caaaagttgg agctttttta
    12301 tgaattggct gacgctctgc gtcttctgta aaaggagctt ccaagtcaat ggtatctccc
    12361 aaaacgttga agacacgtcc caaagtttct ttacctactg gtacagagat tggacgacct
    12421 gtgtccaata cttccattcc acgagtcaac ccatctgttg attccatggc gatagtacga
    12481 accataccat ctcctaactc caaggctact tcaaggacga tttttgtttt tctttcgtca
    12541 tttttgtaga cgacaagtgc attgttaatc tcaggaagtt tttcccctgc tgcaaacaaa
    12601 acgtctacaa cgggaccgat aacctgagca attttacctg aactcatctc cttctcctat
    12661 tctatataag atactgtcgg ttcctagctc aactaggtcc taagttcatt ttcatacgag
    12721 ctggactaga gcctattcta aggcactagc acctgctacg atttctgtaa tttcttgtgt
    12781 aatcgccgcc tgtctggcac ggttatactg aattgtcaaa tcattgatga ctttcttagc
    12841 attatctgtc gctgtttgca tggctgtcat acccgcagca ttctcagctg tcttggcatc
    12901 tataatggca ccgtaaatca tactttctgc aaactgaggc aacaactgct ccagaatttc
    12961 ttctcggctg gtttccaatt caaaagtcaa gctgtactct tcatccgctt catttggatc
    13021 caagtcaaca atcggaagca tttgttccac acgcatttga ctggttagcg tattgacatg
    13081 gtggttgtag caaacataaa gctcatcaaa gagttcattt tggtacattt caacagtttt
    13141 tgaaataatc ttacgaactt gatcaaagct aggttggtct gccaagccac gtaattcata
    13201 aagtggttga ataccgcgag ccttaaagaa atcagctccc atcccaccga tacagatcat
    13261 ttcaaaacct ttaccgtctg ggtggtattc ttctttcaac tccataacag ctttcaaaat
    13321 agaggaatta taacctccaa ccaaaccgcg gtctgaagtg ataacgatat agcctgtctt
    13381 cttcacagaa cggctaatca acatcggatt agttgaagca ccagctccat taccatgaag
    13441 gatatctgtc aaaagtttac gcactttctg agcgtaaact tggaagttgc gagcagcttc
    13501 ttcagagcga cctagcttag cagccgatac catttgcatg gcattagtga tttgactcgt
    13561 attttttgtt gaggcgattt ttgttttaat atcatttaga gatactgcca tctgacacct
    13621 ctattcttat tggaagctag attgattgag aaactctgta atcgcagcat ccaagactgc
    13681 ttcttctggc aagtcttttg tatcacgaat ggtttccaaa atctctggat gttgagcatc
    13741 aaagaaggca tggaactctt cctcgaaacg aacaatatca tctactggaa cagtatccaa
    13801 gaaaccatgt atcaaagcat aaagaatggt tacttgtttc tcaacaggta atggtttgtg
    13861 aacaggttgt ttcaagacct caacggtacg acgtccacgg ttcaacttag cctgtgttgc
    13921 tgcgtccaag tcagaaccaa acttagtaaa ggcttccaac tcacggtatg aagcaaggtc
    13981 gatacgaagt gtaccagcaa ccttcttcat ggctttgatt tgtgcagaac cacctacacg
    14041 agatacagat gaacccgcat cgatggctgg acgaatacct gcattgaaga ggccatcgcc
    14101 aaggaagatt tgtccatcag tgatagaaat cacgttggtt gcgatatagg ctgagatatc
    14161 tcctgcttgt gtctcgataa atggtagggc tgtaattgat ccaccaccaa gttcatcaga
    14221 aactttagct gagcgctcaa gcaaacggct gtggagatag aaaacatccc ctgggaaggc
    14281 ttcacgacct ggaggacgac gaagcaagag cgacagttca cgataagcta ccgcttgttt
    14341 tgatagatca tcgtatacaa tcaaaacatg cttaccttga tacataaatt cttccgccat
    14401 agcgacccca gtataaggag ctaggaagag caatggagat ggttgtgaag cagaggctgt
    14461 cacaacgatt gtgtagtcca aggcaccgta ctgacgaagt gtttctactt gcgtacgaac
    14521 tgttgattct ttttgtccaa tcgcgacgta gatacagatc atatcttgat ctttttggtt
    14581 caagattgta tcaatcgcaa tggttgtttt ccctgtctga cggtcaccga taatcaactc
    14641 acgttgacca cgaccaatcg gtacaagggc gtcaatagct ttcaaaccag tttgcaatgg
    14701 ttctgaaaca gacttacgtt gcataacacc aggagctggt gcttctactg gacgagtttt
    14761 atcagtgtgg atttctccaa gaccgtcaac tggacgacca agcggatcca caacacgacc
    14821 aatcagactt tcacctacag ggacttccat gattttccct gtacggcgga ttgtatcgcc
    14881 ttcacggata tctgtaaagt cacctaggat gataatacca acgtctgttg actccaagtt
    14941 ttgagccata ccataagagc cgttttcaaa attcaacaac tctccactca tgacattttc
    15001 aaggccgtga gcacgcgcga taccgtcccc gatataggtt acaacacctg tttcagtcac
    15061 atcaaaattg ggtttgaaat tttcaatttg ttgcttaatt aaagcgctga tttcttgtgc
    15121 gttaattgcc aaaagaacac cactttctat ttcaaatttt ctttaacaac tttaagttgt
    15181 tgtttaatac tcacatcaat tgtcttgtga ttggcaaaaa tgacaaaacc accaatgaga
    15241 ctttcatcga tttgttcttt tacactcctt actttcagag acattttttt ctcaatcaaa
    15301 gggagcaaac gagtcttctg ttcatcagtt agaggatgag cagacgtaat cgtcacttca
    15361 aatcgatttg tttctttttc aagtcggttc aagcaatcta caagcacatc ataaaaaaga
    15421 tttgctctgt gattgtaggc cagaacctgg ataaagtttt gtaataaagg cgacacagaa
    15481 tcttggaaaa aagcaattgt tttttcctta tccgactcgt ctactgccac ttgttttaaa
    15541 aaagaaggca gacctgtttt ttcaacaact tgcttgattt gagtcaagtc tgaaaagata
    15601 cggtcttctt ctcctttttc aagtaccaat tggacaaaag gcatgctgta tttttcaatt
    15661 acctttactg ttttcttgtc cattaagctt ctcctagctg atcgatatac tgatcaatga
    15721 gtgctttatg ggcatgactg tcaaggtttt gtgagatgat tttaccagct aagctgatgg
    15781 tcagatctgc gacctcaccc ttaacactct gtaaagcttc tactttattt tgagcaattt
    15841 cttgattggc tttttctttt aagtgtcctg cttctagttt agcatctgct aagatattag
    15901 ccttactttg ctcagctgtt tcctttgcat tttcaatgat tgtcttagct tctttacggc
    15961 taccagccaa ttcatcttcg cgtttttgag ccaatacttc tgctttttga cgggcttctt
    16021 cagctctgtc aatatctgaa gcaatttttt cagctctttc ttcgaaaatg cctgtaatat
    16081 tagaccatgc aaatttttta atcaagacta gcaaaagaat aaaagagcca gtgattaaaa
    16141 taaaattacc aattaattca cctactgtta cgtgcatcag ttactccttt ctattcctct
    16201 tcaatattaa tcttattccc taaatacaca gatgtcaaaa gagtaaaaac ataagcttgg
    16261 atgcaggaaa taaagacaga aaatgcagtc caagccaaat tagctccaaa ggctactgga
    16321 taccaataaa tagcttggtg ggaaagaaga agtaacaaac tcgtcatgac ctctcctgca
    16381 aagatattcc caaaaatccg caaagccaaa gataagaagt ttgtaaattc ttccaagata
    16441 ttcatcggta tgacaaaaac aggactcata aaagatttta tacttttttt aaatccacga
    16501 cgacgaacgc tttctatatg tgtcaacaaa atgacaagaa aagataaggt taagtcatac
    16561 tgtaaattag cggttggcga actccaccag ttagtcccat cgatcgtttg aagctttgtc
    16621 attaagccaa ggttattggc aatcaccatg aaaaggaata aacaaaggaa aaagagtgaa
    16681 taatctttca tgtagcgcga accaatgtta ggttctgtaa atccaataac aaagtcatag
    16741 acatactcaa gtacattttg ctttcctttg ggtttcaagg tcatattgcg gcttgcccaa
    16801 taaataaaga caaaaataac tcccacaatc aacaaagtca tggctaacat agtcagattg
    16861 aagataacag gaccaataga gatgattgga ttaatacttt cttccatcta aaatcctccc
    16921 ttttcttctc gttccatgta tttatttgat aataaatgag aagacaagag ttacaaagaa
    16981 agttccttca ataaaggcaa cacctaaaaa catcaaacta cgaaactcag aaagcatatc
    17041 tggttggcgt gctactgatt taaacagtcc attcatcaat aaaccttcac cgacagatac
    17101 gcccatacag gcaatacata agcctaaaaa tgttaaattc ataacaaatt ctcctttaaa
    17161 ataaaattta cttacttagt gtagtcctaa aatttaaatt tgtcaacttt taaccgctat
    17221 tggaagcgtt taataaaaat tatttccatt ttgctaaatt tcaagttcaa gttagccatc
    17281 ca
//
LOCUS       DAVBEO010000048        16132 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 009
            SAMEA1678075-rid20185393.denovo.048, whole genome shotgun sequence.
ACCESSION   DAVBEO010000048 DAVBEO010000000
VERSION     DAVBEO010000048.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678075
            Sequence Read Archive: ERR226392
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 16132)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16132)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980207.1
            Genome Coverage       :: 150x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:50:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 72 of 147
            Pseudo Genes (incomplete)         :: 72 of 147
            Pseudo Genes (internal stop)      :: 42 of 147
            Pseudo Genes (multiple problems)  :: 32 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16132
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678075-rid20185393.denovo.048"
                     /strain="KS 009"
                     /db_xref="taxon:1313"
     gene            145..6831
                     /locus_tag="VQ543_001661"
     CDS             145..6831
                     /locus_tag="VQ543_001661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Ig-like domain-containing protein"
                     /protein_id="HET2612351.1"
                     /translation="MGKGHWNRKRVYSIRKFAVGACSVMIGTCAVLLGGNIAGESVVY
                     ADETLITHTVEKPKEEKMIVEEKADKALETKNVVERTEQSEPSSTEAIASEKKEDEAV
                     TPKEEKVSAKPEEKAPRIESQTSNQEKPLKEDAKAVTNEEVNQMIEDRKVDFNQNWYF
                     KLNANSKEAIKPDVDVSTWKKLDLPYDWSIFNDFDHESPAQNEGGQLNGGEAWYRKTF
                     KLDEKDLKKNVRLTFDGVYMDSQVYVNGQLVGHYPNGYNQFSYDITKYLHKDGRENVI
                     AVHAVNKQPSSRWYSGSGIYRDVTLQVTDKVHVEKNGTTILTPKLEEQQHGKVETHVT
                     SKIVNTDDKDHELVAEYQIVERGGHAVTGLVRTASRTLKAHESTSLDAILEVERPKLW
                     TVLNDKPALYELITRVYRDGQLVDAKKDLFGYRYYHWTPNEGFSLNGERIKFHGVSLH
                     HDHGALGAEENYKAEYRRLKQMKEMGVNSIRTTHNPASEQTLQIAAELGLLVQEEAFD
                     TWYGGKKPYDYGRFFEKDATHPEARKGEKWSDFDLRTMVERGKNNPAIFMWSIGNEIG
                     EANGDAHSLATVKRLVKVIKDVDKTRYVTMGADKFRFGNGSGGHEKIADELDAVGFNY
                     SEDNYKALRAKHPKWLIYGSETSSATRTRGSYYRPERELKHSNGPERNYEQSDYGNDR
                     VGWGKTATASWTFDRDNAGYAGQFIWTGTDYIGEPTPWHNQNQTPVKSSYFGIVDTAG
                     IPKHDFYLYQSQWVSVKKKPMVHLLPHWNWENKELASKVADSEGKIPVRAYSNASSVE
                     LFLNGKSLGFKTFNKKQTSDGRTYQEGANANELYLEWKVAYQPGTLEAIARDESGKEI
                     ARDKITTAGKPAAVRLIKEDHAIAADGKDLTYIYYEIVDSQGNVVPTANNLVRFQLHG
                     QGQLVGVDNGEQASRERYKAQADGSWIRKAFNGKGVAIVKSTEQAGKFTLTAHSDLLK
                     SNQVTVFTGKKEGQEKTVLGTEVARVRTLIGKEPKMPKTVGFVYSDGSREKLPVTWSQ
                     VDVSQAGVVTVKGTANGREVEAHVEVLAIAKELPTVKRIAPNTDLNSVDKSVSYVLTD
                     GSVQEYEVDSWEITEVDKAKLSVAGSRIQMTGQLAGETIHATLVVEEGNAAAPVVPTV
                     TVGGEAVTGLTSRQPMQYRTLSYGAQLPEVTASAENADVTVLQASAANGMRASIFIQP
                     KDGGPLQTYAIQFLEEAPKIAHLSLQVEKADSLKEDQTVKLSVRAHYQDGTQAVLPAD
                     KVTFSTSGEGEVAIRKGMLELHKPGAVTLKAEYEGAKGQVELTIQANTEKKIAQSIRP
                     VNVVTDLHQKPTLPTTVTVEYDKGFPKAHKVTWQAIPKEKLDSYQTFEVLGKVEGIDL
                     EARAKVSVEGIVSVEEVSVTTPIAEAPQLPESVRTYDSNGHVSSAKVAWDAIRIEQYA
                     KEGVFTVNGRLEDTQLTTKLHVRVSAQTEQGANISDQWTGSELPLAFASDSNPSDPVS
                     NVNDKLISYNNQPANRWTNWNRTNPEASVGVLFGDSGILSKRSVDNLSVGFHEDHGVG
                     APKSYVIEYYVGKTVPTAPKNPSFVGNEDHVFNDSANWKPVTNLKAPAQLKAGEMNHF
                     SFDKVETYAVRIRMVKADNKRGTSITEVQIFAKQVAAAKQGQIRIQVDGKDLANFNPD
                     LTDYYLESVDGKVPAVTASVSNNGLATVVPSVREGEPVRVIAKAENGDILGEYRLHFT
                     KDKNLLSHKPVAAVKQARLLQVGQALELPTKVPVYFTGKDGYETKDLTVEWEEVPAEN
                     LTKAGQFTVRGHVLGSDLVAEVTVRVTDKLGEALSDNPNYDENSNQAFASATNDIDKN
                     SHDRVDYLNDGDHSENRRWTNWSPTPSSNPEVSAGVIFRENGKIVERTVAQAKLRFFA
                     DSGTDAPTKLVLERYVGPEFEVPTYYSNYQAYDADHPFNNPENWEAVPYRADKDIAAG
                     DEINVTFKAVKAKAMRWRMERKADKSGVAMIEMTFLAPSELPQESTQSKILVDGKELA
                     DFAENRQDYQITYKGQRPKVSVEENNQVASTVVDSGEDSLPVLVRLVSESGKQVKEYR
                     IQLTKEKPVSAVQEDLPKLEFVEKDLAYKTVEKKDSTLYLGETRVEQEGKTGKERIFT
                     AINPDGSKEEKLREVVEAPTDRIVLVGTKPVAQEAKKPQVSEKADTKPIDSSEASQTN
                     KAQLPNTGSAASQAAVAAGLALLGLSAGLVVTKGKKED"
     gene            complement(7079..7935)
                     /locus_tag="VQ543_001662"
                     /pseudo
     CDS             complement(7079..7935)
                     /locus_tag="VQ543_001662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270419.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(8146..8505)
                     /locus_tag="VQ543_001663"
     CDS             complement(8146..8505)
                     /locus_tag="VQ543_001663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004249826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3397 domain-containing protein"
                     /protein_id="HET2612352.1"
                     /translation="MGMILMKLASILLLILTLVVCIILTKLFRLKKLGRNFADLAFPV
                     LVFEYYLITAKTFTHNFLPRLGLALSILAIILVFFFLLKKRSFYYPKFIKFFWRAGFL
                     LTLIMYIEMIVELFLMK"
     gene            8597..9553
                     /locus_tag="VQ543_001664"
                     /pseudo
     CDS             8597..9553
                     /locus_tag="VQ543_001664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002881980.1"
                     /note="This family includes YhcC from E. coli K-12, an
                     uncharacterized radical SAM protein.; internal stop;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01212 family radical SAM protein"
     gene            9537..10094
                     /locus_tag="VQ543_001665"
     CDS             9537..10094
                     /locus_tag="VQ543_001665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HET2612353.1"
                     /translation="MKRPLEMAHDFLAEVVTKEDVVVDATMGNGHDTLFLAKLAKQVY
                     AFDIQKQALEKTQERLHQADLTNAQLILQGHETLDQFVIKAKAGIFNLGYLPSADKSV
                     ITRPQTTIEALEKLCGLLVKGGRIAIMIYYGHEGGDLERDAVLDFVIQLNQQEYTAAI
                     YRTLNQVNNPPFLVMIEKLERYRHG"
     gene            10087..10341
                     /locus_tag="VQ543_001666"
     CDS             10087..10341
                     /locus_tag="VQ543_001666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000361102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2612354.1"
                     /translation="MDKQYLHEKLDAMRQNFVESTHHERSVGVLDQAHMSKKMLKIKK
                     KLVALEMERCQRKIEHKDCSKIDQKIKEQKEIFESCCKKD"
     gene            10353..12407
                     /locus_tag="VQ543_001667"
     CDS             10353..12407
                     /locus_tag="VQ543_001667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000421632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HET2612355.1"
                     /translation="MELLIYLILFLLVLIVSSTTNKLLPFLPLPLVQILLGIVIGLFL
                     PNTDFHLNTELFLALVIGPLLFREAEEADVTAILKHWRIIVYLIFPVIFISTLSLGGL
                     AHLLWFSLPLAACLAVGAALGPTDLVAFASLSERFSFPKRVSNILKGEGLLNDASGLV
                     AFQVALTAWTTGAFSLGQASSSLIFSILGGFLIGFLTAMTNRFLHTFLLSVRATDIAS
                     ELLLELSLPLVTFFLAEEVHVSGIIAVVVAGILKASRFKKITLLEAQVDTVTETVWHT
                     VTFMLNGSVFVILGMELEMIAEPILTNPIYNPLLLLLSLIALTFVLFVIRFIMIYGYY
                     AYRTRRLKKKLNKYMKDMFLLTFSGVKGTVSIATILLIPSNLEQEYPLLLFLVAGVTL
                     VSFLTGLLVLPHLSDEEEESKDYLMHIAILNEVTLELEKELEDTRNKLPLYAAIDNYH
                     GRIENLILSQENQDDQEDWAALKLLILSIESDGLEQAYEEGNISNRAYRVYQRYLKNI
                     EQGINRKLASRLTYYFLVSLRILRFLLHEVFTLGKTFRSWKDKEQSRLRALDYDQIAE
                     LYLANTEMIIESLENLKGVYRRSLISFMQESRLRETAIISSGAFVERVINRVKPNNID
                     EMLRGYYLERKLIFEYEEKRLITTKYAKKLRQNVNNLENYSLKEAANTLPYDMVELVR
                     RN"
     gene            12586..13446
                     /locus_tag="VQ543_001668"
     CDS             12586..13446
                     /locus_tag="VQ543_001668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihY/virulence factor BrkB family protein"
                     /protein_id="HET2612356.1"
                     /translation="MKKWWKELIDKPLLKAFLHYYQASDSELTSVAVAYYWLISIFPL
                     LLVVVNILPYFQIPVGEFLCFMKDVLPPSLYEGVEKIAREVLTQPSTGLLSFSVLSAL
                     WSFSKSMNFLQKAFNKAYGVEKSRGLISHQMLSLLVSFGLQLLFAFALFLILFGQMIL
                     ALLAHYWTKDGIIYQALQGLAGPLIYALLFAILVMLYYFLPNLSNRKISYTLPGSAFV
                     LLVILGLLTLFSSYLNYYVHHLVDVRILGSVLLVVMMFWFILIAKIVILGAVINASMQ
                     SLKDPVFKKD"
     gene            13657..14367
                     /gene="ccdA2"
                     /locus_tag="VQ543_001669"
     CDS             13657..14367
                     /gene="ccdA2"
                     /locus_tag="VQ543_001669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000509848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     membrane protein CcdA2"
                     /protein_id="HET2612357.1"
                     /translation="MGHIFFFLSVFLAGILSFFSPCILPLLPVYTGVLLDDKDGAQAS
                     SGKFSISVTSLLRTLAFIAGISFIFILLGYGAGFLGDLLYASWFQYLTGAIIILLGLH
                     QMEILHFKGLYKEKRLQLQGQGQNGKGYSQAFLLGLTFSFAWTPCVGPVLGSVLALAA
                     SGGSGAWQGAGLMLVYTLGLALPFLLLALTSSYVLKHFRKLHPYLGILKKVGGFLIIV
                     MGLLVLFGNASILSQLFE"
     gene            14387..14953
                     /locus_tag="VQ543_001670"
     CDS             14387..14953
                     /locus_tag="VQ543_001670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redoxin family protein"
                     /protein_id="HET2612358.1"
                     /translation="MKKWQTCVLGAGSLLCLTACSGKSVTSEHQTKDEMKTEQTASKT
                     SAAKGKEVADFELMGVDGKTYRLSDYKGKKVYLKFWASWCSICLASLPDTDEIAKEAG
                     DDYVVLTVVSPGHKGEQSEADFKNWYKGLDYKNLPVLVDPSGKLLETYGVRSYPTQAF
                     IDKEGKLVKTHPGFMEKDAILQTLKELA"
     gene            14964..16076
                     /gene="msrB"
                     /locus_tag="VQ543_001671"
     CDS             14964..16076
                     /gene="msrB"
                     /locus_tag="VQ543_001671"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HET2612359.1"
                     /translation="MNDKLKIFLLLGVFFLAITGFYVLLIRNAGQTDASQIEKAAVSQ
                     GGKAVKKTEISKDADLHEIYLAGGCFWGVEEYFSRVPGVTDAVSGYANGRGETTKYEL
                     INQTGHAETVHVTYDAKQISLKEILLHYFRIINPTSKNKQGNDVGTQYRTGVYYTDDK
                     DLEVINQVFDEVAKKYDQPLAVEKENLKNFVVAEDYHQDYLKKNPNGYCHINVNQAAY
                     PVIDASKYPKPSDEELKKTLSPEEYAVTQENQTERAFSNRYWDKFESGIYVDIATGEP
                     LFSSKDKFESGCGWPSFTQPISPDVVTYKEDKSYNMTRMEVRSRVGDSHLGHVFTDGP
                     QDKGGLRYCINSLSIRFIPKDQMEEKGYAYLLDYVD"
BASE COUNT         4901 a         3052 c         3565 g         4614 t
ORIGIN      
        1 catatctacg gcaaggcgac actgacgaag tttgaattgg attttcgcag agtgtaaatt
       61 gttgaaacta ggttgtcata ccatgtatac cacttgggct ttggtagtag ctaactgcac
      121 taaatataat ataaggaggg ttttatgggg aaaggccatt ggaatcggaa aagagtttat
      181 agcattcgta agtttgctgt gggagcttgc tcagtaatga ttgggacttg tgcagttcta
      241 ttaggaggaa atatagctgg agaatctgta gtttatgcgg atgaaacact tattactcat
      301 actgttgaga aacctaaaga ggaaaaaatg atagtagaag aaaaggctga taaagctttg
      361 gaaactaaaa atgtagttga aaggacagaa caaagtgaac ctagttcaac tgaggctatt
      421 gcatctgaga agaaagaaga tgaagccgta actccaaaag aggaaaaagt gtctgctaaa
      481 ccggaagaaa aagctccaag gatagaatca caaacttcaa atcaagaaaa accgctcaag
      541 gaagatgcta aagctgtaac aaatgaagaa gtgaatcaaa tgattgaaga caggaaagtg
      601 gattttaatc aaaattggta ttttaaactc aatgcaaatt ctaaggaagc cattaaacct
      661 gatgtagacg tatctacgtg gaaaaaatta gatttaccgt atgactggag tatctttaac
      721 gatttcgatc atgaatctcc tgcacaaaat gaaggtggac agctcaacgg tggggaagct
      781 tggtatcgca agactttcaa actagatgaa aaagacctca agaaaaatgt tcgccttact
      841 tttgatggcg tctacatgga ttctcaagtt tatgtcaatg gtcagttagt ggggcattat
      901 ccaaatggtt ataaccagtt ctcatatgat atcaccaaat accttcacaa agatggtcgt
      961 gagaatgtga ttgctgtcca tgcagtcaac aaacagccaa gtagccgttg gtattcagga
     1021 agtggtatct atcgtgatgt gactttacaa gtgacagata aggtgcatgt tgagaaaaat
     1081 gggacaacta ttttaacacc aaaacttgaa gaacaacaac atggcaaggt tgaaactcat
     1141 gtgaccagca aaatcgtcaa tacggacgac aaagaccatg aacttgtagc cgaatatcaa
     1201 atcgttgaac gaggtggtca tgctgtaaca ggcttagttc gtacagcgag tcgtacctta
     1261 aaagcacatg aatcaacaag cctagatgcg attttagaag ttgaaagacc aaaactctgg
     1321 accgttttaa atgacaaacc tgccttgtac gaattgatta cgcgtgttta ccgtgacggt
     1381 caattggttg atgctaagaa ggatttgttt ggttaccgtt actatcactg gactccaaat
     1441 gaaggtttct ctttgaatgg tgaacgtatt aaattccatg gagtatcctt gcaccacgac
     1501 catggggcgc ttggagcaga agaaaactat aaagcagaat atcgccgtct caaacaaatg
     1561 aaggagatgg gagttaactc catccgtaca acccacaacc ctgctagtga gcaaaccttg
     1621 caaatcgcag cagaactagg tttactcgtt caggaagagg cctttgatac ttggtatggt
     1681 ggcaagaaac cttatgacta tggacgtttc tttgaaaaag atgccactca cccagaagct
     1741 cgaaaaggtg aaaaatggtc tgattttgac ctacgtacca tggtcgaaag aggcaaaaac
     1801 aaccctgcta tcttcatgtg gtcaattggt aatgaaatag gtgaagctaa tggtgatgcc
     1861 cactctttag caactgttaa acgtttggtc aaggttatca aggatgttga taagactcgc
     1921 tatgttacca tgggagcaga taaattccgt ttcggtaatg gtagcggagg gcatgagaaa
     1981 attgctgatg aactcgatgc tgttggattt aactattctg aagataatta caaagccctt
     2041 agagctaagc atccaaaatg gttgatttac ggttcagaaa catcttcagc tacccgtaca
     2101 cgtggaagtt actatcgccc tgaacgtgaa ttgaaacata gcaatggacc tgagcgtaat
     2161 tatgaacagt ctgactatgg aaatgatcgt gtgggttggg ggaaaacagc aaccgcttca
     2221 tggacttttg accgtgacaa cgctggctat gctggacagt ttatctggac aggtacggac
     2281 tatattggtg aacctacacc atggcacaac caaaatcaaa ctcctgttaa gagctcttac
     2341 tttggtatcg tagatacagc cggcattcca aaacatgact tctatctcta ccaaagccaa
     2401 tgggtttctg ttaagaagaa accgatggta caccttcttc ctcactggaa ctgggaaaac
     2461 aaagaattag catccaaagt agctgactca gaaggtaaga ttccagttcg tgcttattcg
     2521 aatgcttcta gtgtagaatt attcttgaat ggaaaatctc ttggttttaa gactttcaat
     2581 aaaaaacaaa ccagcgatgg gcggacttac caagaaggtg caaatgctaa tgaactttat
     2641 cttgaatgga aagttgccta tcaaccgggt accttggaag caattgctcg tgatgaatct
     2701 ggcaaggaaa ttgctcgaga taagattacg actgctggta agccagcggc agttcgtctt
     2761 attaaggaag accatgcgat tgcagcagat ggaaaagact tgacttacat ctactatgaa
     2821 attgttgaca gccaggggaa tgtggttcca actgctaata atctggttcg cttccaattg
     2881 catggccaag gtcaactggt cggtgtagat aacggagaac aagccagccg tgaacgctat
     2941 aaggcgcaag cagatggttc ttggattcgt aaagcattta atggtaaagg tgttgccatt
     3001 gtcaaatcaa ctgaacaagc agggaaattc accctgactg cccactctga tctcttgaaa
     3061 tcgaaccaag tcactgtctt tactggtaaa aaagaaggac aagagaagac tgttttgggg
     3121 acagaagtag caagagttcg tacattaatt ggtaaagaac caaaaatgcc gaaaacagta
     3181 ggttttgtat acagcgatgg tagtcgtgaa aaacttccag taacttggtc tcaagtcgat
     3241 gttagtcaag caggagttgt gactgttaaa ggtacagcaa atggacgtga ggtagaggct
     3301 catgtcgagg ttctagcaat tgcgaaagaa ttaccaacag ttaaacgtat tgctccaaat
     3361 actgacttga attctgtaga caaatctgtt tcttatgttt tgactgatgg aagtgtacaa
     3421 gagtacgaag tagatagctg ggagattacg gaagtagata aagccaaact ttcagtagct
     3481 ggatcacgta ttcaaatgac tggtcagtta gctggagaaa ctattcatgc aacccttgtg
     3541 gtagaagaag gaaatgctgc agcacctgta gtgccaactg ttactgttgg aggtgaggca
     3601 gtaacaggtc ttactagtcg acaaccaatg caatatcgta ctctatctta tggtgcccaa
     3661 ctgccagaag tcacagcaag tgctgaaaat gctgatgtga cagttcttca agcaagcgca
     3721 gcaaacggca tgcgtgcgag catctttatt cagcctaaag atggtggtcc tcttcaaacc
     3781 tatgcaattc aattcctaga agaagcacca aaaattgctc acttgagttt gcaagtggaa
     3841 aaagctgaca gtctcaaaga agaccaaact gtcaaattgt cggttcgagc tcactatcaa
     3901 gatggaacgc aagctgtatt accagctgac aaagtaacct tctctacaag tggtgaaggg
     3961 gaagtcgcaa ttcgtaaagg aatgcttgag ttgcataagc caggagcagt cactctcaaa
     4021 gcggaatatg agggagctaa aggccaagtt gaactcacta tccaagccaa tactgagaag
     4081 aagattgcgc aatctatccg tcctgtaaat gtagtcacag atttgcatca aaaacctact
     4141 cttccaacaa cagtaacggt tgagtatgac aaaggtttcc ctaaagctca caaagtcact
     4201 tggcaagcta ttccgaaaga aaaactagac tcctatcaaa catttgaagt actaggtaaa
     4261 gttgaaggaa ttgaccttga agcgcgtgca aaagtctctg tagaaggtat cgtttcagtt
     4321 gaagaagtca gtgtgacaac tccaatcgca gaagcaccac aattaccaga aagcgttcgg
     4381 acatatgatt caaatggtca cgtttcatca gctaaggttg catgggatgc gattcgtata
     4441 gagcaatacg ctaaggaagg tgtctttaca gttaatggtc gcttagaaga tactcaatta
     4501 acaactaaac ttcatgttcg cgtatctgct caaactgagc aaggtgcaaa catttctgac
     4561 caatggaccg gttcagaatt gccacttgcc tttgcttcag attcaaatcc aagcgaccca
     4621 gtttcaaatg ttaatgacaa gctcatttcc tacaataacc aaccagccaa tcgttggaca
     4681 aactggaatc gtactaatcc agaagcttca gtcggtgttc tgtttggaga ttcaggtatc
     4741 ttgagcaaac gctccgttga taatctaagt gtcggattcc acgaagacca tggagttggt
     4801 gcaccgaagt cttatgtgat tgagtattat gttggtaaga ctgtcccaac agctcctaaa
     4861 aaccctagtt ttgttggtaa tgaggaccat gtctttaatg attctgccaa ctggaaacca
     4921 gttactaatc taaaagcccc tgctcaactc aaggctggag aaatgaacca ctttagcttt
     4981 gataaagttg aaacctatgc tgttcgtatt cgcatggtta aagcagataa caagcgtgga
     5041 acgtctatca cagaggtaca aatctttgcg aaacaagttg cggcagccaa acaaggacaa
     5101 ataagaatcc aagttgacgg caaagactta gcaaacttca accctgattt gacagactac
     5161 taccttgagt ctgtagatgg aaaagttccg gcagtcacag caagtgttag caacaatggt
     5221 ctcgctaccg tcgttccaag cgttcgtgaa ggtgagccag ttcgtgtcat cgcgaaagct
     5281 gaaaatggcg acatcttagg agaataccgt ctgcacttca ctaaggataa gaacttactt
     5341 tctcataaac cagttgctgc ggttaaacaa gctcgcttgc tacaagtagg tcaagcactt
     5401 gaattgccga ctaaggttcc agtttacttc acaggtaaag acggctacga aacaaaagac
     5461 ctgacagttg aatgggaaga agttccagca gaaaatctga caaaagcagg tcaatttacc
     5521 gttcgaggcc atgtccttgg tagtgatctt gttgctgagg tcactgtacg agtgacagac
     5581 aaactaggcg aagctctttc agataaccct aactatgatg aaaacagtaa ccaggccttt
     5641 gcttcagcaa ccaatgatat tgacaaaaac tctcatgacc gcgttgacta tctcaatgac
     5701 ggagatcatt cagaaaatcg tcgttggaca aactggtctc caacaccatc ttctaatcca
     5761 gaagtatcag cgggtgtgat cttccgtgaa aatggtaaga ttgtagaacg gactgttgcc
     5821 caagccaaac ttcgtttctt tgcagatagt ggtacggatg caccaactaa actcgtttta
     5881 gaacgctatg tcggtccaga gtttgaagtg ccaacctact attcaaacta ccaagcctac
     5941 gacgcagacc atccattcaa caatccagaa aattgggaag ctgtgcctta tcgtgcggat
     6001 aaagacatcg cagctggtga tgaaatcaac gtaacattta aagctgtcaa agccaaagct
     6061 atgagatggc gtatggagcg taaagctgac aagagcggtg ttgcgatgat tgagatgacc
     6121 ttccttgcac cgagtgaatt gcctcaagaa agtacgcaat cgaagattct tgtagatgga
     6181 aaagaacttg ctgatttcgc tgaaaatcgt caagactatc aaattaccta taaaggtcaa
     6241 cggccaaaag tctcagttga agaaaacaat caagtagctt caactgtggt agatagtgga
     6301 gaagatagcc ttccagtact tgttcgcctc gtttcagaaa gtggaaaaca agtcaaggaa
     6361 taccgtatcc agttgactaa ggaaaaacca gtttctgctg tacaagaaga tcttccaaaa
     6421 ctcgaatttg ttgaaaaaga tttggcctac aagacagttg agaaaaaaga ttcaacactg
     6481 tatctaggtg aaactcgtgt agaacaagaa ggaaaaactg gtaaagaacg tatctttaca
     6541 gcgattaatc ctgatggaag taaggaagaa aaactccgtg aagtggtaga agctccgaca
     6601 gaccgcatag tcttggttgg aaccaaacca gtagctcaag aagctaaaaa accacaagtg
     6661 tcagaaaaag cagatacaaa accaattgat tcaagtgaag ctagtcaaac taataaagcc
     6721 cagttaccaa atacaggtag tgcggcaagc caagcagcag tagcagcagg tttagctctt
     6781 ctaggtttga gtgcaggatt agtagttact aaaggtaaaa aagaagacta gaaattttga
     6841 taccttcttt atcattaaag accaaagaaa aactcttgtc ctaaatagaa gataaagagt
     6901 ctggaacaaa atagttctca accacaaaaa agctagatat ttccaattgc ggaactctag
     6961 ctttttaatt ttgagtcgtt ctcttattgt atagtagatt gaaactagaa tagtacactt
     7021 ctacttctaa aacattgtta gaaatcaatt tgactgtcct tatcgatttg tcctgttctt
     7081 atttcatttc actatgtttt aggaggttat tggccataag taccaatccc atgtcaattc
     7141 tcacttgacg cttccctctc agattacatc tcttgtaacc caaacaagcc tttatctgcc
     7201 caaagacagg ttccacatca atcttgcgtt gagcgaaaat ctgtctacct tggggagata
     7261 aaagcgcctg acattcttta gctttcaagt tttgatagcg ttcgttcata tacagtccct
     7321 tttgagggac tgattcaggt tcatcagcgt agtaaacctt gatttcctgt tgaaagtctg
     7381 tctgtgtttt ctggtacttg atatggtgaa aacgatagca ccagccatca ggatgtgtgt
     7441 agctatcctc cttgtcatta tagtgccaat tcgctaagtt tttagctgac tgtttatacc
     7501 ctctcttttg ttccttatca aacatggcat atttaatcag aaggggagtg atttcttctt
     7561 gaaaatagac ctgtatctgt tcttgaagtt tggcggagaa tttctctgtc gttttcttcc
     7621 acacaaaact atacttgttg gcattggctt caatcttagt tccgtcaata aacaaacaat
     7681 ctaaggtcac taactcttcc atttttcaat ttttcgacca gagaaaatcc cttgtgaata
     7741 ggcaaataga agagtagata caagcatttt agggtgataa gacgggcgat caaaggcatg
     7801 atagaaggcg tggaagtgac aatcctccaa ggtattcacc actttttcaa tagtaaaaac
     7861 gagatgatct tgtggcaaga aggaactgat ttctagtggt aaagttgttt gatttgtgtt
     7921 atagtgaata tgcatgggat agcctttcta aatggtttat taagcaattc tattttacca
     7981 agactatcgc aaccatgcaa aaaagcaacg gcaaatccgt tgcctttttt ggagataaga
     8041 gactattgtc ccagactctt ttctttgtat aaaattgtat agtgttattg tctatactat
     8101 tttgtagaga aagcaaaaat ccctagaaaa tgcttaggga ttcgactatt tcattaagaa
     8161 caattcaaca atcatttcta tatacatgat aagggttaat aagaatcctg cacgccagaa
     8221 gaatttgata aatttaggat agtaaaagct gcgttttttc aaaaggaaga aaaagacgag
     8281 aataatggct aggatcgaga gggctagccc cagtctaggg aggaaattat gggtaaaggt
     8341 tttagctgta atcaagtaat actcaaatac caagactgga aaagccaaat ccgcaaagtt
     8401 tcgtcctagt ttttttaatc taaaaagttt ggttaggata atgcagacga ctaaggtcag
     8461 tatcaataat aaaatagatg ctaatttcat taaaatcata cccatattgt atcataaaaa
     8521 aaggctaatg gaaacgagaa acagaggaat ttataggaaa gtcaggcttt tgagattgtg
     8581 ggtgattttt gttataatga aagttataaa atcttataat accttgaatg attattatcg
     8641 aaaactcttt ggagaaaaga cttttaaagt ccctattgat gcgggatttg actgtcccaa
     8701 tcgtgatgga actgtggctc atggaggctg tactttttgt acggtttccg gttctggaga
     8761 tgccattgtg gcaccagatg cgcctatccg tgagcaattt tataaggaaa ttgactttat
     8821 tcatcgtaag tggccagatg ttcagaagta tctggtttat tttcaaaatt ttaccaacac
     8881 ccatgaaaag gtggaagtta ttcgagagcg ttatgaacag gctatcaatg agccaggtgt
     8941 ggtaggaatc aatattggaa cgcgcccaga ctgtttacca gacgaaacca tcgaatattt
     9001 ggctgagtta tcggagtgca tgcatgtgac ggttgaattg ggcttgcaaa ctacttatga
     9061 agcaacctct gacctgatta accgtgcgca ttcttatgaa ttgtaggtgg aaacggtcaa
     9121 gcgtttgaga aagtatccaa aaattgagat tgtttcccat ttgatcaatg gtttgcctgg
     9181 tgaaacccat gagatgatgg ttgaaaatgt ccgccgttgt gtcacggata acgatattca
     9241 agggattaaa ctgcatttgc tccatcttat gacaaatact cgtatgcaac gagattacca
     9301 tgaggggcgt ttacaattga tgagtcagga cgaatatgtc agggtcatct gtgaccaact
     9361 ggaaattatt cccaaacata tcgtcatcca tcgaattaca ggagatgcgc ctagggatat
     9421 gctgcttggg cctatgtgga gcctcaataa atgggaagct ctcaacagca ttgagatgga
     9481 gatgcgacgt cgtggaagtg ttcaaggatg caaggctgta aaacaggagt ttgaaaatga
     9541 aaagaccact tgagatggca catgattttt tggctgaggt cgtgacaaaa gaggatgtcg
     9601 tagtggatgc gactatggga aatggtcatg acacgctttt tttagccaag ctagccaagc
     9661 aagtctatgc ctttgatatt cagaagcaag ccttggaaaa gacccaagag cgtttgcatc
     9721 aggctgactt gacaaatgcc cagttaatct tgcaaggcca tgagacactg gaccagtttg
     9781 tgataaaagc taaggcaggg atttttaatc tgggctattt gccgtcagct gataagtctg
     9841 tcatcacccg accgcagaca acgattgagg cattagaaaa gctatgtggc ttacttgtca
     9901 aaggtggacg aattgctatt atgatttact atggtcatga aggaggcgat ctcgagagag
     9961 atgctgtctt ggattttgtg atccagttga accaacaaga gtacacagct gccatttacc
    10021 gaactttaaa ccaagtcaac aacccgccgt ttttagtgat gattgaaaaa ttagagagat
    10081 acagacatgg ataaacaata cctacacgaa aagctggatg ccatgcgcca gaattttgtt
    10141 gaatcaaccc accacgaacg atcggtgggc gtgctagacc aagcgcatat gagcaaaaaa
    10201 atgcttaaaa tcaagaaaaa attagttgct cttgaaatgg aacggtgcca gagaaaaatt
    10261 gagcacaaag actgttccaa gattgaccaa aaaatcaaag agcagaagga gatatttgaa
    10321 tcctgttgta aaaaagatta aggaggacgt gcgtggaatt actgatttac ctcatcctat
    10381 ttttactggt tttgattgtc tcaagtacaa ccaataagct cctgcccttt ttgcctctcc
    10441 ctttggtgca gattcttttg ggaattgtga ttggtctctt tttacccaat actgactttc
    10501 accttaatac ggagttgttt ttggcactgg ttatcggacc cttgcttttc cgagaggctg
    10561 aagaagcaga tgttacggct attttaaaac actggcgaat cattgtttat ctcatatttc
    10621 cagtgatttt tatctcgacc ttgagtttgg gtggcttggc ccatcttctt tggttcagcc
    10681 ttcccttggc agcttgcttg gctgttgggg cagcccttgg tcctacggac ttggtggcct
    10741 ttgcctctct ttcggagcgt tttagctttc ctaagcgcgt gtccaatatt cttaagggcg
    10801 aaggactctt gaatgatgct tctggtttgg tggcttttca ggtagctttg acagcttgga
    10861 caactggagc tttttctctg gggcaagcta gcagttcgct catcttttca atcctaggcg
    10921 gttttttaat tggattttta acggccatga ccaaccgctt cctccatacc ttcttgctaa
    10981 gtgtgcgcgc aacggatatt gccagtgaac ttttattaga attgagtttg cctctagtga
    11041 ccttctttct ggcagaagaa gttcatgttt caggtattat tgccgtcgta gttgctggaa
    11101 ttttaaaggc aagtcgcttc aagaaaatca cgctcctcga agcccaagtg gatacggtga
    11161 ccgagacggt ctggcataca gtgaccttta tgctcaacgg ttctgtcttt gtgattttag
    11221 ggatggagtt ggaaatgata gcagaaccta tcttgaccaa tccaatctat aatcctctac
    11281 ttttattgct atctctcatc gcccttacct ttgtcctctt tgtcattcgt tttattatga
    11341 tctatggcta ttatgcctat agaacccgac gcctcaagaa aaagctaaat aagtatatga
    11401 aggacatgtt tctcttgacc ttttcaggtg ttaagggaac ggtgtcgatt gctacgattc
    11461 tcttgatacc aagtaatcta gaacaggagt atcctctttt gcttttcctt gttgcaggtg
    11521 tgacgcttgt cagcttttta acaggtctct tggtcttgcc tcatctttct gatgaagagg
    11581 aagaaagcaa ggattatctc atgcatatcg ccattttgaa tgaagtaacg ctagagttgg
    11641 aaaaagagtt ggaagacacc agaaataaac ttcccctcta tgcggctatt gacaattatc
    11701 atggacgtat tgaaaatctc attttaagcc aagaaaacca ggatgatcaa gaagattggg
    11761 ctgctttgaa actcttgatt cttagtattg aaagtgatgg tttggaacag gcctatgaag
    11821 aggggaacat tagcaatcgt gcttaccgag tttaccaacg ttatctgaaa aatatagaac
    11881 aaggaatcaa tcgtaaactt gcctcaagac tgacctatta ttttcttgtt tccttgagga
    11941 ttttacgttt tctccttcat gaagttttta ctcttggaaa gaccttccgt agctggaagg
    12001 acaaggagca aagccgtctc cgtgctcttg attatgacca aattgcagag ctctatcttg
    12061 ccaatacaga gatgattatt gaaagtttgg aaaacctgaa gggagtctac agacgctctt
    12121 tgattagttt tatgcaggag tctcgtcttc gagaaacagc tattatcagc agtggtgcct
    12181 ttgtcgaacg ggttatcaat cgtgtcaaac ccaacaatat cgatgaaatg ctgagaggct
    12241 attatctgga gcgcaagttg attttcgaat acgaagaaaa acgattgatt acgactaagt
    12301 atgccaagaa attacgacaa aatgtaaata acttagagaa ctattccttg aaggaagctg
    12361 ccaataccct gccgtatgat atggtggaat tggtaagaag aaattagtta atactcttcg
    12421 aaaatctctt caaaccacgt cagcgtcgcc ttggattata tatgtgactg acttcgtcag
    12481 tttcatctac aacctcaaag cagggctttg agcaacctgc ggctagcttc ctagtttgct
    12541 ctttgatttt cattgagtat aagattataa atgaaggagt atgacatgaa aaagtggtgg
    12601 aaagagctga tagacaagcc tttattaaaa gcttttttgc attattatca agcatcagat
    12661 agtgagttga ccagtgtcgc agtagcctac tattggttga tttcgatttt ccccctgctt
    12721 ttggtggtgg tcaatatcct cccctatttt cagattcctg tgggagaatt tctgtgcttt
    12781 atgaaagacg ttctgccccc aagcctctat gaaggtgtgg aaaaaatagc cagagaagtt
    12841 ttgacgcaac cttcaacagg tttattgagt ttttctgttt tatcggcgtt atggagtttt
    12901 tcaaaatcta tgaatttctt gcaaaaagct tttaacaagg cttatggcgt cgaaaagagt
    12961 cgtggactta tttcccatca gatgctaagt ctcctagtca gttttggctt gcagctcctc
    13021 tttgcgtttg ccttgttttt gatcttattt ggtcagatga ttttggcttt acttgctcat
    13081 tattggacaa aagatggcat tatctatcag gctttacaag ggttggcagg tcctctgatt
    13141 tacgccctcc tctttgctat cttggtcatg ctttattatt ttcttcccaa tctatctaac
    13201 aggaaaatta gctataccct accaggcagt gcctttgttc tcttagtgat tttaggttta
    13261 ctaactctgt tctctagtta tctcaattac tatgtccatc atttggtgga tgtccgaatt
    13321 ttaggttccg ttcttcttgt tgttatgatg ttttggttta tcttgattgc taaaattgtt
    13381 atcctaggcg cggttatcaa tgccagtatg cagagtttga aagatccggt ctttaaaaaa
    13441 gactaactat ttatccatta caaaagcgca tagtatcaaa actttataga accttgatac
    13501 tatgcgcttt tgtgctttga cagttttttg tatagttttt gtccaagatt tctaaatcat
    13561 ctgattaaat tcctattttc ccctatcatt gtccctgttt tttcgaaaat ggaaggagta
    13621 taataaatct atcaataaaa tgataggagg aactttatgg gtcatatttt cttttttcta
    13681 agtgtctttt tggcagggat tctatccttc ttttctcctt gtatcttacc tttgttaccg
    13741 gtctatacag gagtgttact agatgataag gatggtgctc aggcttctag cggcaaattt
    13801 tcaatctcag ttactagttt attacgaact ctggccttta tagcaggaat ttcctttata
    13861 tttattttgt tgggctatgg agctggtttt ttaggcgatt tgctttatgc ttcttggttc
    13921 caatatctta ctggggcaat tattatcctt cttggtttgc accaaatgga gattctacac
    13981 tttaaggggc tttataagga aaagaggcta caactgcaag gacaggggca aaatggtaag
    14041 ggctatagtc aggcattttt attgggcttg acctttagtt ttgcttggac gccttgcgtg
    14101 gggccggttc tggggtctgt tttggccttg gcggcttcag gtggttcagg agcttggcag
    14161 ggagctggtc tcatgttggt gtatacgctg ggcttggcgc taccattctt gcttctagct
    14221 ctgacctcta gttatgtttt gaaacatttc cgaaaacttc atccctatct cggaatcctc
    14281 aaaaaagtgg gtggttttct cattattgtg atgggactct tggttctgtt tggaaatgct
    14341 tcaattttaa gtcaattatt tgaataaaat ggaaaggaat atcaatatga aaaaatggca
    14401 aacatgtgtt cttggagcag gttcgctcct ttgtttgacg gcttgttcag gcaagtccgt
    14461 gactagtgaa caccaaacga aagatgaaat gaagacggag cagacagcta gtaaaacaag
    14521 cgcagctaaa gggaaagagg tggctgattt tgaattgatg ggagtagatg gcaagaccta
    14581 ccgtttatct gattacaagg gcaagaaagt ctatctcaaa ttctgggctt cttggtgttc
    14641 catctgtctg gctagtcttc cagatacgga tgagattgct aaagaagctg gtgatgacta
    14701 tgtggtcttg acagtagtgt caccaggaca taagggagag caatctgaag cggactttaa
    14761 gaattggtat aagggattgg attataaaaa tctcccagtc ctagttgacc catcaggcaa
    14821 acttttggaa acttatggtg tccgttctta cccaacccaa gcctttatag acaaagaagg
    14881 caagctggtc aaaacacatc caggattcat ggaaaaagat gcaattttgc aaactttgaa
    14941 ggaattagcc taggaggtgt cttatgaatg ataagttaaa aatcttcttg ttgctaggag
    15001 tattttttct agccataacc ggtttctatg ttctattgat acgaaatgca gggcagacag
    15061 atgcctcgca aattgaaaag gcggcagtta gccaaggagg aaaagcagtg aaaaaaacag
    15121 aaattagtaa agacgcagac ttgcacgaaa tttatctagc tggaggttgt ttctggggag
    15181 tggaggaata tttctcacgc gttcccgggg tgacggatgc cgtttcaggc tatgcaaatg
    15241 gtagaggaga aacaaccaag tacgaattga ttaaccaaac aggtcatgca gaaaccgtcc
    15301 atgtcaccta tgatgccaag caaatttctc tcaaggaaat cctgcttcac tatttccgca
    15361 ttatcaatcc aaccagcaaa aataaacaag gaaatgatgt ggggacccag taccgtactg
    15421 gtgtttatta cacagatgac aaggatttgg aagtgattaa ccaagtcttt gatgaggtgg
    15481 ctaagaaata cgatcaacct ctagcagttg aaaaggaaaa cttgaagaat tttgtggtgg
    15541 ctgaggatta ccatcaagac tatctcaaga aaaatccaaa tggctactgc catatcaatg
    15601 ttaatcaggc ggcctatcct gtcattgatg ccagcaaata tccaaaacca agtgatgagg
    15661 aattgaaaaa gaccctgtca cctgaggagt atgcagttac ccaggaaaat caaacagaac
    15721 gagctttctc aaaccgttac tgggataaat ttgaatccgg tatctatgtg gatatagcaa
    15781 ctggggaacc tctcttttca tcaaaagaca aatttgagtc tggttgtggc tggcctagtt
    15841 ttacccaacc catcagtcca gatgttgtca cctacaagga agataagtcc tacaatatga
    15901 cgcgtatgga agtgcggagc cgagtaggag attctcacct tgggcatgtc tttacggatg
    15961 gtccacagga caagggcggc ttacgttact gtatcaatag cctctctatc cgctttattc
    16021 ccaaagacca aatggaagaa aaaggctacg cttatttact agattatgtt gattaatact
    16081 cttcgaaaat ctcttcaaac cacgtcagcg tcgccttacc gtatgtaggg tt
//
LOCUS       DAVBEO010000049        15135 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 009
            SAMEA1678075-rid20185393.denovo.049, whole genome shotgun sequence.
ACCESSION   DAVBEO010000049 DAVBEO010000000
VERSION     DAVBEO010000049.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678075
            Sequence Read Archive: ERR226392
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 15135)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15135)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980207.1
            Genome Coverage       :: 150x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:50:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 72 of 147
            Pseudo Genes (incomplete)         :: 72 of 147
            Pseudo Genes (internal stop)      :: 42 of 147
            Pseudo Genes (multiple problems)  :: 32 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15135
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678075-rid20185393.denovo.049"
                     /strain="KS 009"
                     /db_xref="taxon:1313"
     gene            complement(<1..210)
                     /locus_tag="VQ543_001672"
     CDS             complement(<1..210)
                     /locus_tag="VQ543_001672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000530076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET2612360.1"
                     /translation="MEQLHFITKLLDIKDTNIQIIDVVNRDSHKEIIAKLDYDAPSCP
                     ECGNQLKKYDFQKPSKIPYLETTGMP"
     gene            296..997
                     /locus_tag="VQ543_001673"
     CDS             296..997
                     /locus_tag="VQ543_001673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001827799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit R"
                     /protein_id="HET2612361.1"
                     /translation="MYSGFTHYKYYRAEIIRKVQEPEFWKEVNLSDLEKIRLAIRDLL
                     QFLDKTDRKPYYVNFEDRILSTVHETTAFLQVNDLRSYNEKVEHYLKTHLDEESISKL
                     YHNKKLTSDDMLALEKLLWEKLGSKADYQSHYENKAIPRLVREIIGLDRESANRIFSK
                     FLSDENLNARQISFVKLIVDYIVENGFLETKVLTQEPFKSYGSVQLLFQHQLPVLRNI
                     VQIIELINNRAGEAA"
     gene            complement(1397..2743)
                     /locus_tag="VQ543_001674"
                     /pseudo
     CDS             complement(1397..2743)
                     /locus_tag="VQ543_001674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808790.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS1380-like element ISSpn5 family transposase"
     gene            2805..2999
                     /locus_tag="VQ543_001675"
     CDS             2805..2999
                     /locus_tag="VQ543_001675"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2612362.1"
                     /translation="MSSKKHPLGEKRNHTGSKLRQGFWMVFRLGVNNWGFKEIENKKP
                     SKNSIAGENEIILNENQRAN"
     gene            2977..3177
                     /locus_tag="VQ543_001676"
     CDS             2977..3177
                     /locus_tag="VQ543_001676"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2612363.1"
                     /translation="MKIKEQTRKLAAGCSKHCFEVVDKTDEVSSKHGFEVVDETDEVS
                     NHTYGKATLTRIEEIFEEYKSS"
     gene            complement(3257..3702)
                     /locus_tag="VQ543_001677"
                     /pseudo
     CDS             complement(3257..3702)
                     /locus_tag="VQ543_001677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000547411.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            3710..3853
                     /locus_tag="VQ543_001678"
     CDS             3710..3853
                     /locus_tag="VQ543_001678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2612364.1"
                     /translation="MAERFWENLSIILADRNISWIELTRKMFAGEFHYPSELNRLYQK
                     IRH"
     gene            3946..4533
                     /locus_tag="VQ543_001679"
     CDS             3946..4533
                     /locus_tag="VQ543_001679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000821297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET2612365.1"
                     /translation="MKRIIPVYIFQQVNVLLVSLYLLKFLCSDELTILQILYGASLIS
                     FLWMYGQRKQVIKVNMKTRIQWLGIGFVSLLIISLCFSLIHAQESTNQANLIGLQHQI
                     PWFSFLLFLINASMVEEFLYREILWNLVRKLDIRVALTSVLFALAHHPGTIIAWCLYV
                     SLGMFLGLVRYKLDLWGSMGLHLVWNLLVYSLLLF"
     gene            4933..5742
                     /locus_tag="VQ543_001680"
     CDS             4933..5742
                     /locus_tag="VQ543_001680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000926538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HET2612366.1"
                     /translation="MLLQKELIPMIEANLPNMAYAEKDIAKFFLKQQPLNNYSCKALC
                     ECLNVSKATLTRFAKKCGFKGFRQFIFKYQEMIREKEKLALYTEATEKVLSDYEEMLR
                     KTYTVLDEVQLERIAEMIETAERVYLYGKVSSVLALQEMKMRFMRLGVIGEVLSDEDM
                     ILWNSLLLNENCLVIGASVSGQTDIVLEGLQKAADKGAKTVLMTTRKFDEEDCFFDEL
                     LLLASTNHLSYGNRISPQFPILLITDCLFSHYLESPERQYYYNQTIIHKEE"
     gene            5747..6448
                     /locus_tag="VQ543_001681"
     CDS             5747..6448
                     /locus_tag="VQ543_001681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HET2612367.1"
                     /translation="MSQIWTKEKFISQVHGGVIVSCQALPGEPLYNEEFSLMPFMAKA
                     ALEAGAVGIRANSVRDIKAIQKVVDLPIIGIIKRDYPPQEPYITATMKEVDELVECGT
                     TVIAFDATLRPRYDGLVINEFIKKIKEKYPNQLLMADVSNFDEGLYAFKSGVDFVGTT
                     LSGYTSTSVQSDEPDFELMKKLADFNIPVIAEGKIHYPEQLKKAYSLGVTSVVIGGAI
                     TRPKEIAQRFINVIK"
     gene            6473..7390
                     /locus_tag="VQ543_001682"
     CDS             6473..7390
                     /locus_tag="VQ543_001682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylneuraminate lyase"
                     /protein_id="HET2612368.1"
                     /translation="MKDLTKYKGVIPAFYACYDENGEISQERVKSLVQYFIDKGVKGI
                     YVNGSSGECIYQSVEDRKQIIEAVMEVAKGKLTVINHVACNNTKDSIELAKHSESVGV
                     DAIAAIPPIYFKLPEYSIAAYWNAMSEAAPNTDFIIYNIPQLAGVALTGSLYATMRQN
                     PRVIGVKNSSMPVQDIQMFVAAGGEDYIVFNGPDEQYLGGRLMGAEAGIGGTYGVMPD
                     LFLKLESLIQERDLDTAKKLQYAINEVIYKMISGKANMYAVAKEVLRLNEKLDLGSVR
                     QPLEALAEGDLEVAKQAAELIQQARKEFL"
     gene            7418..8959
                     /locus_tag="VQ543_001683"
     CDS             7418..8959
                     /locus_tag="VQ543_001683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000537364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:solute symporter"
                     /protein_id="HET2612369.1"
                     /translation="MGTTGFTIIDLIILIVYLLAVLVAGIYFSKKEMKGKEFFKGDGS
                     VPWYVTSVSIFATMLSPISFLGLAGNSYAGSWILWFAQLGMVVAIPLTIRFILPIFAR
                     IDIDTAYDYLDKRFNSKALRIISALLFIIYQLGRMSIIMYLPSAGLSVLTGIDINILI
                     ILMGAVAIVYSYTGGLKSVLWTDFIQGVILISGVVLALFVLMANIKGGFGAVAETLAN
                     GKFLAANEKLFDPNLLSNSIFLIVMGSGFTILSSYASSQDLVQRFTTTQNIKKLNKML
                     FTNGVLSLATATVFYLIGTGLYVFYQVQNAGSAASNIPQDQIFMYFIAYQLPVGITGL
                     ILAAIYAASQSTISTGLNSVATSWTLDIQDVISKNMSDDRRTKIAQFVSLAVGLFSIG
                     VSIVMAHSDIKSAYEWFNSFMGLVLGLLGGVFILGFVSKKANKQGAYAALIVSTIVMV
                     FIKYFLPPTAVSYWAYSLISISVSVVSGYIVSVLTGNKVSAPKYTTIHDIPEIKADSS
                     WEVRH"
     gene            8978..9436
                     /locus_tag="VQ543_001684"
     CDS             8978..9436
                     /locus_tag="VQ543_001684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000587138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HET2612370.1"
                     /translation="MIISEQSDFRRYASINKHFSKVCDFLENTNLTDLVDGKVDIDGE
                     NVFANCMIYLADGVPGDIFETHKKYLDIHIVVENTEKMAVTSPVRAQSRVPFSEEKDI
                     AFYDSKDYQIVELLPGNMLVTFEEDLHQPKIHCNDEPVKKLVIKVLNEEK"
     gene            9438..11660
                     /locus_tag="VQ543_001685"
     CDS             9438..11660
                     /locus_tag="VQ543_001685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000739354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exo-alpha-sialidase"
                     /protein_id="HET2612371.1"
                     /translation="MKKNIKQYVTLGTAVVLSAFVANSVAAQETETSEVSTPELVQPV
                     APTTPISEVQPKSGNSSEVTVQPRTVETTVKDPSSATEETPVLEKNNVTLTGGGENVT
                     NELKDKFTSGDFTVVIKYNQSSEKGLQALFGISNSKPGQQNSYVDVFLRDNGELGMEA
                     RDTSSNKNHLVSRPASVWGKYKQEAVTNTVAVVADSVKKTYSLYANGTKVVEKKVDNF
                     LNIKDIKGIDYYMLGGVKRAGKTAFGFNGTLENIKFFNSALDEETVKKMTTNAVTGHL
                     IYTANDTTGSNYFRIPVLYTFSNGRVFSSIDARYGGTHDFLNKINIATSYSDDNGKTW
                     TKPKLTLAFDDFAPVPLEWPRDVGGRDLQISGGATYIDSVIVEKNNKQVLMFADVMPA
                     GVSFREATRKDSGYKQIDGNYYLKLKKQGDTDYNYTIRENGTVYDDRTNRPTEFSVDK
                     NFGIKQNGNYLTVEQYSVSFKNNKKTEYRNGTHVHMNIFYKDALFKVVPTNYIAYISS
                     NDHGESWSAPTLLPPIMGLNRNAPYLGPGRGIIESSTGRILIPSYTGKESAFIYSDDN
                     GASWKVKVVPLPSSWSAEAQFVELSPGVIQAYMRTNNGKIAYLTSTDAGTTWSAPEYL
                     KFVSNPSYGTQLSIINYSQLIDGKKAVILSTPNSTNGRKHGQIWIGLINDDNTIDWRY
                     HHDVDYSNYGYSYSTLTELPNHEIGLMFEKFDSWSRNELHMKNVVPYITFKIEDLKKN
                     "
     gene            11700..12809
                     /locus_tag="VQ543_001686"
     CDS             11700..12809
                     /locus_tag="VQ543_001686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HET2612372.1"
                     /translation="MVNYGIVGAGYFGADLARSMNKIEDAKVVAVFDPNHGEEVAQEL
                     GSDVCASLDELVAREDIDCVIVASPSYLHREPVVKAAQHGKHVFCEKPIALSYEDCKA
                     MVDACKENNVIFMAGHIMNFFNGVHHAKELITQGKIGKVLYCHAARTGWEEQQPTVSW
                     KKLRSQSGGHLYHHIHELDCIQFIMGGLPEKATMVGGNVYHKGENFGDEDDMLIVNLE
                     YSDDRYAVLEYGNAFRWGEHYVLIQGTEGAIKLDLFNTGGTLRVKGEGESHFLVHETQ
                     EEDDDRTAIYTGRGMDGAIAYGKPGVRCPLWLQTCIDKEMEYLHDIIKGGEITEEYEK
                     LLNGVAALESIATADACTLSVKEDRKVSLSEITNA"
     gene            12966..13856
                     /locus_tag="VQ543_001687"
     CDS             12966..13856
                     /locus_tag="VQ543_001687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HET2612373.1"
                     /translation="MKIIGIDIGGTTIKADLYNEFGTSLNQFKEIETIIDYDLGTNQI
                     LNQVCDLIGEYILNHSIDGVGISTAGVVNANTGEIIYTGYTIPGYIGVNFTFEIEKRF
                     GLSTFVENDVNCAALGELWKGQAKDKKNVVMVTIGTGIGGSIIVNGQIVNGFNYTAGE
                     VGYIPVGNSDWQSKASTTALIHLYQKKSLKTNQTGRTFFTDLRAGDKVAKETFEIFVE
                     NLTKGLLTITYLLNPEILILGGGILAKKDILLPEIQSSLAKNAMDNRFLPKNLVAATL
                     GNEAGRIGAVKNFLDRISNK"
     gene            13881..14204
                     /locus_tag="VQ543_001688"
     CDS             13881..14204
                     /locus_tag="VQ543_001688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000185366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2612374.1"
                     /translation="MTNSVFSTMQDIENVATDIIKSYDNEIYTYKAVSQEELEKLEKS
                     YDEKSHEELVSIESNLEMKQQNLIDEVNKTIKENYEKIQYISSSRRGEFVEKIIGRVV
                     EKYGY"
     gene            14194..>15135
                     /locus_tag="VQ543_001689"
     CDS             14194..>15135
                     /locus_tag="VQ543_001689"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018351.1"
                     /note="Produces ATP from ADP in the presence of a proton
                     gradient across the membrane. Subunit I is part of the
                     membrane proton channel; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit I"
                     /protein_id="HET2612375.1"
                     /translation="MAISQMKRISLLFSKSSLDDVLKTIQELESVQFRDLKVQDNWSE
                     ALEKDEVVFPTIQISHTSNSNHGVIEGNDALIYLMNQQQYLEATVEKLQEYLPKENTF
                     KLLQQPPITTSYEELEKFGKANVAEGVLKKVNRQINRVHELERHIQSNNEEIERLIKW
                     EKLEIIPAHLEQFFFCKGKVGTIPRTVDNRLYNSFLENNIEVQEIFSNDREYGVVVFY
                     QSSCSIDFDEYLFEPFDYSRKELPKQRVVDLDQENMQLITEKENIIASLQDSKNNLID
                     LQWQIDYILSIYARQISKNNLLSTPHLVALEGWIEETR"
BASE COUNT         5051 a         2306 c         2996 g         4782 t
ORIGIN      
        1 aggcatacca gtcgtttcaa gataaggaat tttagaaggt ttttgaaagt catatttctt
       61 caattggttt ccgcactcag ggcaagatgg ggcgtcgtag tccagtttgg cgatgatttc
      121 cttgtgtgaa tccctattga cgacatctat aatttggata tttgtgtctt tgatatcgag
      181 tagttttgtg ataaaatgta attgttccat atgaatcttt ctaatgagtt gtttggtcgc
      241 ttttcattat agatcttatg ggactttttt tctacaataa aataggctcc ataatatcta
      301 tagtggattt acccactaca aatattatag agccgaaatt atcaggaaag tacaggagcc
      361 tgaattttgg aaagaagtta acttgtctga tttggaaaaa attcgtcttg ctattcgaga
      421 tttattacag tttttggata aaacagaccg taaaccctac tatgttaact ttgaagatcg
      481 tatactctcc actgttcacg agaccacagc atttttgcag gtcaacgatc ttcggtctta
      541 caatgaaaaa gttgagcatt atttgaaaac tcatctggat gaggagtcca tttctaagct
      601 ataccataat aaaaagttga catctgatga tatgcttgca cttgaaaaat tgctttggga
      661 aaaattaggt agtaaagcag actaccaaag tcattatgaa aataaggcaa ttccgagatt
      721 ggttcgtgag attattggct tagatagaga gtctgccaat cgtattttct ctaaattttt
      781 gtcggatgag aatcttaatg ccaggcagat ttcatttgta aaattgattg tagactacat
      841 tgtagaaaat ggttttttag agacgaaagt gttaacgcaa gagccgttta aatcttatgg
      901 ttctgttcaa ctactcttcc aacaccaact accagtactt cgtaatattg ttcaaatcat
      961 tgaacttatc aataatcgag ctggagaagc ggcttaaatt ctaaagtgat tgccatgctg
     1021 agactcattt aaaattaaaa agagtagaaa tttatgctat atatgagaag ttttattagg
     1081 aagaatgtca tcgttttcct agaatacagt atcagttgtt aagtggttga taaatttcaa
     1141 agtagatact tgtaccacga tgtttgttga tcgagttatt aacaaaagag ctactttgat
     1201 tttaacccaa atcattcata cctctctcaa ctagatgtaa cttacaaaac ccctgacctc
     1261 atgagccact ttcttcctcc tcatgaggtc agttttactt tctgctgttc cagtatcgtt
     1321 tttcctcgct agatttcctc aaaagggcag actcctccct tggtgcgtca cacgattttt
     1381 tcatctcgac tgttctttaa tgcatcatta acgacgcttt tcttccaggt ggttcataag
     1441 gaacaggaag attcaggttg acttttctaa tcctagaata aagtgctgaa aacaattcgg
     1501 aataggcata gagactagac aatttgagga gctgcttgcg tcctgttcga acacattttc
     1561 ctaccacgtg aagaaaaaga tggcggaagc gtttgattgt taaagtttgg aagtcacctc
     1621 cagctagatg tttgagaaaa agatagagat tgtaggcgat acagctcatc atcatacgaa
     1681 cttcgttttt gattaaggtt gaactatccg ttttatcgcc aaaaaatccc tccttcatct
     1741 ccttgatgaa attctcggct tgaccacgtc cacgataaag ctgaaactgg tcttggcttg
     1801 ttccactcgt catatttgta acgagagaaa taacatcgta gaacaagttt ccttcttttc
     1861 gttcagagaa ctggcagaca cgacgcttgt gcgaccaaga tcctgcttga tagagagttt
     1921 ctgagtaggc ggagtggggc aagatggtta agtcctcatc ctgtgggcaa gggagggaaa
     1981 ggtctccaag acggctcaga acagtatttt tcttgagttt tatgagttag tattgccctg
     2041 ttttttcaat taaatcgtat aatttggggg tcgcaaagcc actatccatt cgaaagagaa
     2101 gttgattaaa ccgttctaaa acaggtgtga taaagctgtc tgcctcttca gaacaataac
     2161 gattaccagg acgaagctgg gcattgaaac aataacctgt cttcccctcg aaagcataaa
     2221 gaggatgata gccatgagca cgatagtggg cgttataagc aacaccttct tgcttgccat
     2281 aagttgtgaa atgggtagaa tcgatatcta caatgagttg gtttagctgg tgaaactgta
     2341 aaaagaattc gaccaattca aggttgaggc atcgcaaact atggactgtt tcctcgtcag
     2401 ttctggaaag aaaacgggat aaggttggct gtgaagcaag ctgccctcct tccaacaatt
     2461 ttggaaagta ggcatcagct gacaattctt tacaagcata gtccgttcca tagcctgtta
     2521 acagttgaaa gaggaactgg acaaggatat ctgaatccga ataacgacag tagcggcgtt
     2581 ggtcattcgt tactaaatac ttagaaatcc gctcttttag tttcaactgg gaaaaaagtt
     2641 cctgaaaaaa gataagacca ccatactggg ttaaatgacc tccatcgaaa gatagttggt
     2701 aaaaagactt gttttggaag tgatgatttg gtaaactgtt catgtgagtt tcctttcttt
     2761 ttgtgttttt ttctacactt ataccataaa ggggaaattc ttttttgtct agtaaaaaac
     2821 acccattggg tgaaaaaaga aaccatacag gatctaagct aaggcaagga ttctggatgg
     2881 tttttagatt aggggtgaat aattggggtt ttaaagaaat agaaaacaaa aagccgagca
     2941 agaattcaat tgcaggagaa aatgaaataa tactcaatga aaatcaaaga gcaaactagg
     3001 aaactagctg caggctgctc aaaacactgt tttgaggttg tagataagac tgacgaagtc
     3061 agctcaaaac atggttttga ggttgtagat gaaactgacg aagtcagtaa ccatacctac
     3121 ggcaaggcga cgttgacgcg gattgaagag attttcgaag agtataaatc ttcctaggat
     3181 aaagcaaaga gcctgggaca aaatagttct cgaccacaaa aaagctagag atttccaatt
     3241 gtggaacttt agctttttaa ttttgagtcg ttctcttatt gtattttagg aggttattgg
     3301 ccataagtac caatcccatg tcaattctca cttgacgctt gcccctcaga ttacatctct
     3361 tgtaacccaa acaagccttt atctgcccaa agacaggtga cattctttag ctttcaagtt
     3421 ttgatagcct tcgttcatat acagtccctt ttgaggggct gattcaggtt cgtcggcgta
     3481 gtaaaccttg atttcttgtt taaagtctgt ctgtgttttc tgatgtttgg tatggtgaaa
     3541 acgataatac cagccatcag gatgtgtata gctatcctcc ttgtcattat agtaccaatt
     3601 cgctaagttt ctagctgact gtttatagcc tctcttctgt tccttatcaa acatggcata
     3661 tttaatcaga tggtttacct ccttttcatc taactaaagg agaagcaata tggctgaacg
     3721 attttgggag aacttgtcca ttattttggc tgacagaaat atcagctgga ttgagttaac
     3781 cagaaaaatg tttgcgggag agtttcacta tccaagtgaa ttgaatcgtt tgtatcaaaa
     3841 gattcgccac tagaagatgg aacaacgaat gcctcaaagt ccatgggtag aaaggattgt
     3901 gcaggtatta gatttagatt atgaagattt atttcggagg taattatgaa aagaataatt
     3961 ccagtttata tattccaaca agtaaatgtc ctattggtat ctctatactt attgaaattt
     4021 ctttgtagcg atgagttaac tatactacag attctctatg gagcgtcact catttctttt
     4081 ttatggatgt atggtcaacg aaaacaagtg atcaaggtta atatgaaaac taggatacaa
     4141 tggcttggta ttggattcgt tagcctactg attataagtc tatgttttag tctaatccat
     4201 gcgcaagaaa gcacgaatca agcaaactta attggacttc aacatcaaat tccttggttt
     4261 tcatttttat tgtttttaat caatgcgagt atggttgaag aatttctgta tagagaaatt
     4321 ttatggaact tggttagaaa attagatatt cgagttgctt tgacaagtgt tttatttgcc
     4381 ttagcacatc atccaggaac cattatagct tggtgtttgt atgtatcgct ggggatgttt
     4441 ttagggcttg tacgctacaa attggactta tggggcagta tggggctaca tttggtgtgg
     4501 aacctactag tttatagttt gctgcttttt taaaataagt gatctgattt atctcataaa
     4561 tcagtagttt ttataggatt atttttaatt cggaaacaaa aatgtattaa cagcataaaa
     4621 taaagaaact aggaacattt tttttatttt ttagaaataa aatgttgtat agaaattccg
     4681 aaagaaataa taaaatcaaa ataaaaatta ataaaatagg tatatttgaa catattgacg
     4741 tcgacaaatg ttcttgcaag acataaaata caaataaaaa gaataaaaaa tttttatatt
     4801 tttatatttg ttgttctgtt ataaaatgaa agaaattaga aactagtttc taaatcatga
     4861 aaaatattga aaaaaaaaaa aataagtgtt aaaataaaga atgtaaacgt ttacttcaat
     4921 aaaggagctc atatgttact gcaaaaagaa ctaattccaa tgatagaagc taacttacca
     4981 aatatggcat atgctgaaaa agacattgct aaattcttct taaaacagca acctctgaat
     5041 aattattcat gtaaggcatt gtgcgaatgc cttaatgtat ccaaagcaac attgactcga
     5101 tttgcgaaaa aatgtggttt taaaggtttt agacaattca ttttcaaata ccaagagatg
     5161 attcgtgaga aagaaaagtt agcattgtat acagaggcta cagaaaaagt tttatccgac
     5221 tatgaagaaa tgttgagaaa aacttacacg gttcttgatg aagttcaact tgagcgtatt
     5281 gctgagatga tagaaactgc tgagcgtgta tatctttatg gtaaagtaag ttctgttctt
     5341 gctttacaag aaatgaagat gagatttatg cgtctcggag tcattggtga agtattatca
     5401 gacgaggata tgattttgtg gaatagctta ttacttaatg aaaattgcct tgtcattgga
     5461 gcatccgttt caggtcaaac tgatattgta ctagaaggtc ttcaaaaagc tgcggataaa
     5521 ggcgctaaaa cagttttaat gactacaaga aaatttgacg aagaagattg tttctttgat
     5581 gaactattgt tattagcttc gaccaatcat ctctcgtatg gcaatcgcat atcacctcag
     5641 tttccaatac ttttaattac agactgctta ttctctcatt atctggaaag tccagagaga
     5701 caatattatt acaatcaaac tattatccat aaggaggaat aataaaatga gtcaaatttg
     5761 gactaaagaa aaatttataa gtcaagtcca tggtggagtc attgtttctt gtcaagcttt
     5821 acccggtgaa cccctttata atgaagaatt tagcttgatg ccttttatgg ctaaagcagc
     5881 tttagaggca ggagcagtgg gcattcgcgc aaattctgtg cgtgatatta aagcaattca
     5941 gaaagtagta gatttaccaa taattggaat tatcaaaaga gattatccac ctcaagaacc
     6001 atatattact gctacgatga aagaagtaga tgaacttgta gaatgcggaa caacagtcat
     6061 tgcatttgat gcaactttaa gaccaagata tgatggctta gttatcaatg aatttatcaa
     6121 aaaaataaaa gaaaaatatc ctaatcaatt gttgatggcg gatgtaagta attttgatga
     6181 aggtctctat gcatttaaat caggcgttga ttttgttggt acaacattat cagggtacac
     6241 aagtacaagt gtacaatcag atgagcctga ttttgaacta atgaaaaaat tggctgattt
     6301 taatattccg gtaattgccg aaggaaaaat tcattatcca gaacaattaa aaaaagctta
     6361 tagtttaggt gttaccagtg ttgtcattgg tggagcgatt acacgtccaa aagaaattgc
     6421 tcagcgattt attaatgtca tcaaataaaa aacaatataa aggagaaatc tgatgaaaga
     6481 tttaactaaa tacaaaggcg ttattcctgc attttatgct tgctatgatg aaaatggtga
     6541 aattagccaa gaacgtgtaa aatctctggt gcaatatttc attgacaaag gtgtaaaagg
     6601 tatctatgta aatggttctt caggtgaatg tatttaccaa agtgtagaag atcgtaaaca
     6661 aattattgaa gctgttatgg aagttgctaa aggtaaatta acagttatca accatgttgc
     6721 atgtaataac acgaaagata gtattgaatt ggcaaaacat tcagaaagtg ttggagtcga
     6781 tgctattgct gctatcccac ctatttactt caaattgcca gaatattcaa ttgcagcata
     6841 ttggaatgca atgagtgaag ctgcgccaaa tacagatttt atcatttata atattccaca
     6901 attggcaggg gttgcgttga ctggtagttt gtatgcaaca atgcgtcaaa atcctcgtgt
     6961 gattggagtt aaaaattctt ctatgcctgt acaagatatt caaatgtttg tagctgcagg
     7021 tggagaagat tacattgtat tcaatggtcc agatgaacaa tatcttggtg gtcgcttgat
     7081 gggagcagaa gctggtattg gtggtactta tggcgttatg ccagatttgt tcttgaaatt
     7141 ggaaagtttg attcaagaac gagatttaga tactgctaaa aaacttcaat atgctatcaa
     7201 tgaagttatc tataagatga tatcaggtaa ggcaaatatg tatgctgtag caaaagaggt
     7261 tttgcgtcta aatgaaaaac ttgatttagg ttctgttcgt caacccttag aagcattggc
     7321 agaaggtgac ttggaagttg caaaacaagc agcagaactt attcaacaag cacgaaaaga
     7381 atttttataa taaataaaat caatatggag atatgttatg ggcacaacag gatttacaat
     7441 aattgactta attatcttga ttgtttattt acttgcggtg ttggttgcag gtatctattt
     7501 ctctaaaaaa gagatgaaag gaaaagagtt cttcaaagga gatggttcgg ttccttggta
     7561 tgttacttcg gtatccattt ttgccacaat gctcagtccg atttccttct tgggactcgc
     7621 tggtaactct tatgcaggta gctggatttt atggtttgct caattaggga tggtagtagc
     7681 tattccactg acaattcgtt ttatcttacc tatctttgca cggatagaca tcgatacggc
     7741 atatgattac ttggataaac gttttaattc taaagcactt cgtattattt cagcactctt
     7801 gtttattatt tatcaattgg gacgtatgtc tatcattatg tacctcccat cagctggttt
     7861 atcagtattg acaggaattg acatcaatat tttgattatt ttgatgggtg cagttgcaat
     7921 tgtttattct tacactggtg gtctaaaatc cgtattatgg acagacttta ttcaaggtgt
     7981 gattctgatt agtggtgtcg ttttagcttt atttgtactg atggctaata ttaaaggtgg
     8041 ctttggtgca gtagcagaaa cattagcaaa cgggaaattc cttgctgcaa atgaaaaact
     8101 tttcgatcct aacttgcttt caaactccat ctttttaatt gtgatgggtt caggctttac
     8161 aatcttgtct tcctatgctt catctcaaga tttggttcaa cgttttacta caacacaaaa
     8221 tattaagaaa cttaataaga tgttgttcac aaacggtgtc ttgtcacttg caactgcaac
     8281 agtcttttac ttgattggta caggcttgta cgtattctat caagtacaaa atgcaggtag
     8341 tgcagctagc aatatccctc aagaccaaat ctttatgtac tttattgcat accagttacc
     8401 agtaggtatc acaggtttga ttttggcagc gatttatgca gcatctcaat caactatttc
     8461 aacaggtttg aactctgttg caacttcatg gacattggat attcaagatg tcatttctaa
     8521 aaatatgtca gacgatcgtc gtacgaaaat tgcacaattc gtatctctag cagtaggttt
     8581 attctcaatt ggtgtttcca ttgtcatggc tcactcagat attaaatctg catacgaatg
     8641 gttcaatagc ttcatgggac ttgtacttgg tctacttggt ggtgtattta ttcttggatt
     8701 tgtttctaaa aaagcaaata aacaaggtgc ttatgcagcg ctgattgtat caactatcgt
     8761 catggtattt attaaatact tccttcctcc aacagctgtg agctactggg catattcatt
     8821 gatttcaatc tctgtatcag tagtttcagg ttatattgta tctgttctta ctggaaataa
     8881 agtatctgca cctaaatata caacgattca tgatattcca gaaattaaag cggattcaag
     8941 ttgggaagtt cgtcactaat agaaaagaga aaataatatg attatttctg aacaatctga
     9001 ttttagacga tatgcttcta tcaataaaca tttttcaaaa gtctgtgatt ttttagaaaa
     9061 tacaaatttg acagatttag ttgatggaaa agttgatatt gacggggaaa atgtttttgc
     9121 aaattgtatg atctatctag ctgatggagt cccaggagat atttttgaaa ctcataagaa
     9181 atatttagat attcatattg ttgttgaaaa tactgaaaaa atggcagtaa cttccccagt
     9241 tcgtgcccag tcacgtgtac cttttagcga agaaaaggat attgcttttt acgatagcaa
     9301 agactatcaa attgttgaat tgcttccagg gaatatgttg gtgacttttg aagaagatct
     9361 tcaccaacca aagattcatt gcaatgatga gcctgttaaa aaacttgtta ttaaagtttt
     9421 aaacgaggaa aaataaaatg aaaaaaaata ttaaacaata cgtaacctta ggtactgcag
     9481 tggtattatc agcatttgtt gctaactcag ttgcagctca ggagactgaa acttctgaag
     9541 tatcaacacc agagttggtg caacctgttg caccaacgac tccgatttcg gaagtacaac
     9601 ctaaatcggg taactcttcg gaagttactg tacaacctag aacagtcgaa actactgtta
     9661 aggatccatc ttctgcaacg gaagaaactc ctgtcttaga aaaaaataat gttactttaa
     9721 cagggggcgg agaaaatgtt actaatgagt taaaggataa atttactagc ggtgacttta
     9781 ctgtagtgat taagtacaat cagtctagtg agaaaggctt acaagctctg tttggaatat
     9841 ctaattctaa acccggtcaa caaaatagtt atgtagatgt gttccttaga gacaatggtg
     9901 aattgggaat ggaagcgcgt gatacttctt ccaataaaaa tcacctagta tccagacctg
     9961 cttcagtttg gggtaagtac aaacaagaag ctgtgactaa cactgttgca gtagtagcag
    10021 attcagtcaa aaaaacatat tctttatatg caaatggtac aaaagtagta gaaaagaaag
    10081 tggataactt cttaaacatc aaggatatta aaggtattga ttactatatg cttgggggag
    10141 tgaaacgtgc aggaaaaacg gcgtttggtt ttaacggaac actagaaaat atcaaattct
    10201 ttaatagtgc attggatgaa gaaactgtta aaaagatgac aacaaacgct gttactggac
    10261 atttaattta tacggctaat gatacaacag gttctaacta tttccgtatt ccagttctgt
    10321 atacttttag caatggtcgg gtattttcaa gcattgacgc tcgttacggc ggaactcatg
    10381 attttttgaa taaaattaat attgctacaa gttatagtga tgataatggt aagacatgga
    10441 ctaaaccaaa attaacattg gcattcgatg attttgcgcc agtaccatta gaatggcctc
    10501 gtgatgttgg tggacgtgac ttacaaatca gcggtggtgc aacctatatt gactctgtta
    10561 ttgttgaaaa aaataacaaa caagtactca tgtttgcgga tgtgatgcct gctggagtaa
    10621 gttttagaga agctactaga aaagattcag gttataaaca aattgatggt aattattacc
    10681 ttaaattaaa gaaacaaggt gatactgatt acaattatac tattcgtgag aatggtactg
    10741 tatacgacga tcgtaccaac agaccaactg aattttcagt agataaaaat ttcggtatta
    10801 aacaaaatgg taattatttg acagtagagc aatattcggt ttcatttaaa aataataaaa
    10861 agactgaata tcgtaatggg actcacgtcc atatgaatat cttctacaaa gatgcattgt
    10921 tcaaagtagt gccaacgaac tatattgcat atatttctag caatgatcat ggcgaatctt
    10981 ggtctgcacc aactttatta cctcctataa tgggacttaa tcggaatgcg ccttatttgg
    11041 gtcctggacg tggaatcatt gaaagctcaa ctggacgtat tcttattccg tcttacactg
    11101 gtaaagagtc tgcattcatt tatagtgacg ataatggagc atcttggaaa gttaaagttg
    11161 tgccacttcc ttctagttgg tcagcagaag cacaatttgt agaattgagt ccaggagtaa
    11221 ttcaagcata catgcgtaca aataatggta aaattgcata tttaacaagt acagacgcag
    11281 gtactacttg gagtgcaccg gaatatttga aatttgtttc aaatccaagt tatggaacac
    11341 aattatcaat catcaattat agtcaactga ttgatggtaa aaaggctgtc attttaagta
    11401 ctccaaactc cacaaatggt cgtaaacacg gacaaatttg gattggtcta attaatgatg
    11461 ataatacaat tgattggcgt tatcatcacg acgttgatta tagtaactat ggatactcat
    11521 attcaacatt gacagagtta ccaaatcatg aaattggatt gatgtttgaa aaatttgatt
    11581 catggtctcg taatgaactt catatgaaaa atgttgtacc atatataaca tttaagattg
    11641 aagatctgaa aaagaattaa agctgaaatt tgaaaatata taaaaagagg ataaaaatta
    11701 tggtaaatta cggtattgtt ggagctggat attttggagc tgatttagct cgctcaatga
    11761 acaaaattga agatgcaaaa gtggttgcgg tatttgaccc aaatcatgga gaagaagttg
    11821 ctcaagagtt gggatcagat gtttgtgcaa gtttagatga acttgtagca cgtgaagata
    11881 ttgattgtgt gatcgtagct tcacctagct accttcaccg tgaaccagtt gtgaaagctg
    11941 ctcaacatgg caaacacgta ttttgtgaaa agccaattgc attgtcttat gaagattgta
    12001 aagccatggt tgacgcatgt aaagaaaata atgttatctt tatggctggt cacatcatga
    12061 acttctttaa cggtgtacac catgctaaag aattgattac tcaaggtaaa atcggtaaag
    12121 ttctttattg ccatgccgct cgtacaggtt gggaagaaca acaaccaact gtatcatgga
    12181 agaaacttcg ttctcaatct ggaggacatt tgtaccatca tattcatgaa ttagattgca
    12241 ttcagtttat catgggagga cttcctgaaa aagcgacaat ggtaggaggc aatgtatatc
    12301 ataaaggtga aaactttggt gatgaagatg atatgctcat tgtaaactta gaatactctg
    12361 atgatcgtta tgctgttttg gaatatggta atgctttccg ttggggtgaa cactacgtct
    12421 tgattcaagg aactgaagga gctatcaaac ttgatttgtt caatactgga ggtactcttc
    12481 gtgttaaagg tgaaggagaa tcacacttct tagttcatga aactcaagag gaagatgatg
    12541 accgtacagc tatctatacc ggtcgtggta tggatggagc aattgcgtac ggtaaaccag
    12601 gagtacgttg cccattatgg ttgcaaacat gtattgataa agaaatggaa tatctacatg
    12661 acatcattaa aggtggagaa attacagaag aatatgaaaa acttctcaat ggtgtagctg
    12721 ctttagaatc aatcgctacc gctgatgcat gtactttatc agttaaagaa gatcgaaaag
    12781 taagtctttc agaaatcaca aatgcttaac ttttgtaaaa cagaatagta aattcttatc
    12841 attatataat ttctaaagtt ctgtgataca actcattgaa taaagaaata gagatgggac
    12901 tgggataatg cccagtccca ttttttatca aaaagtaatg agatcaaaaa tgtgggagtg
    12961 atgaaatgaa gattataggg atcgatattg gcggaacaac aattaaagca gatttataca
    13021 atgagtttgg aacgagttta aatcagttca aagagataga aacaattatt gactatgatt
    13081 tgggaacgaa ccagatatta aatcaggtct gtgatttaat tggtgagtat attttaaatc
    13141 attcaattga tggtgttggg atttccactg ctggagttgt taatgctaat acaggagaga
    13201 tcatctatac aggctataca ataccagggt atatcggagt aaactttact ttcgaaatag
    13261 aaaaacgttt tgggttgtct acttttgttg aaaatgatgt taattgtgct gcattaggtg
    13321 aattgtggaa gggacaagcc aaagataaga aaaatgtagt aatggttact attggaacag
    13381 gtataggagg cagtattatt gtcaatggac aaattgttaa cggatttaac tatactgctg
    13441 gtgaagtagg ctatattcct gtaggtaatt cggattggca aagcaaagcc tcaacaaccg
    13501 cattgattca tttatatcaa aagaaaagct tgaaaactaa tcaaactggg cgtactttct
    13561 ttactgattt aagagctgga gataaagtcg ctaaagaaac ttttgaaatt tttgtagaaa
    13621 atctaacaaa aggtttatta acgattactt atctacttaa tccagaaatt ctcatattag
    13681 gaggtgggat cctggctaaa aaggatattt tgttacctga aattcaaagt tctttagcta
    13741 aaaatgcaat ggataatagg tttttgccta aaaatcttgt ggcagctaca ttaggaaatg
    13801 aagctggtcg tataggagct gtaaaaaatt tcttagatag aatttctaat aaatagtatg
    13861 aaagataagg aggtgtcaca atgactaact ctgtattttc gacaatgcaa gatattgaga
    13921 atgttgcaac cgatattata aaatcatatg ataatgagat ttatacttat aaagctgttt
    13981 cccaagaaga attggaaaaa ctagaaaaaa gttatgatga aaaaagtcac gaagaattag
    14041 tttcaataga aagcaattta gaaatgaaac aacagaacct tattgatgag gttaataaaa
    14101 caatcaagga aaattatgaa aagattcagt atatttcatc aagtaggaga ggagaatttg
    14161 tagaaaaaat tattggtagg gtggtagaaa aatatggcta ttagtcagat gaaaagaatt
    14221 tctctactat tttctaaaag tagtcttgat gatgttttaa aaactattca agaactagag
    14281 tcagtgcagt tccgtgattt aaaggttcag gataactggt cagaagctct agaaaaagat
    14341 gaggttgtat ttccaactat tcaaatttct catacttcta attccaatca tggggttatt
    14401 gaaggaaatg atgccttgat ttatttgatg aatcaacaac aatatttaga agcaactgta
    14461 gagaaattac aagaatacct accgaaagaa aacacgttta aattattaca gcaacctccg
    14521 ataacgacct cttatgaaga attagaaaaa tttggtaaag ctaatgttgc tgagggtgtt
    14581 cttaaaaaag tgaatcgtca aataaacaga gttcatgaat tagaaagaca cattcaaagt
    14641 aataatgagg aaatagagag attaataaaa tgggaaaaat tagaaattat tcctgcgcat
    14701 ttagaacaat tttttttctg taaaggaaaa gtcggaacaa ttccaaggac tgtagataat
    14761 cgcttataca atagtttttt agaaaacaat attgaagttc aagaaatatt ttctaatgat
    14821 agagagtacg gtgttgttgt tttctatcag tccagttgct ctattgattt tgatgaatac
    14881 ttatttgaac catttgatta ttctagaaag gaattaccga agcagcgagt agtagatttg
    14941 gatcaagaaa acatgcagtt aataactgaa aaagagaata ttatcgcatc gttgcaagat
    15001 tcaaagaata atttgataga tttacaatgg caaattgact atattttatc tatctatgct
    15061 cgtcaaatct ctaagaataa ccttttgagc actccgcatc tagttgcact agaaggatgg
    15121 atagaagaaa ctcgt
//
LOCUS       DAVBEO010000050        14254 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 009
            SAMEA1678075-rid20185393.denovo.050, whole genome shotgun sequence.
ACCESSION   DAVBEO010000050 DAVBEO010000000
VERSION     DAVBEO010000050.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678075
            Sequence Read Archive: ERR226392
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 14254)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14254)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980207.1
            Genome Coverage       :: 150x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:50:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 72 of 147
            Pseudo Genes (incomplete)         :: 72 of 147
            Pseudo Genes (internal stop)      :: 42 of 147
            Pseudo Genes (multiple problems)  :: 32 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14254
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678075-rid20185393.denovo.050"
                     /strain="KS 009"
                     /db_xref="taxon:1313"
     gene            3..350
                     /locus_tag="VQ543_001690"
     CDS             3..350
                     /locus_tag="VQ543_001690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001273322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2612376.1"
                     /translation="MLRLPYKKQKISHFTVSEDKDICRYIRQQLYYQNLFWMKEQAEA
                     YQKGENILTYGLKEWYPQIRPIVGKFFQIEQDLTSYYQHFYTYYQKNPQNDWQKLYPP
                     AFYQQYFLKNMVE"
     gene            369..2171
                     /gene="pepF"
                     /locus_tag="VQ543_001691"
     CDS             369..2171
                     /gene="pepF"
                     /locus_tag="VQ543_001691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HET2612377.1"
                     /translation="MVLQRNEINEKDTWDLSTIYPTDQAWEEVLKDLTEQLETVAQYE
                     GHLLDSADNLLEITEFSLEMERQMEKLYVYAHMKNDQDTREAKYQEYYAKAMTFYSQL
                     DQAFSFYEPEFMEISEKQYADFLEAQPKLQVYQHYFDKLLQGKDHVLSQREEELLAGA
                     GEIFGSASETFAILDNADIVFPYVLDDDGKEVQLSHGIYTRLMESKKREVRRGAYQAL
                     YATYEQFQHTYAKTLQTNVKVQNYRAKVRNYKSARHAALAANFVPESVYDNLVAAVRK
                     HLPLLHRYLELRSKILGISDLKMYDVYTPLSSVEYSFTYQEALKKAEDALAVLGEDYL
                     SRVKRAFSERWIDVYENQGKRSGAYSGGSYDTNAFMLLNWQDNLDNLFTLVHETGHSM
                     HSSYTRETQPYVYGDYSIFLAEIASTTNENILTEKLLEEVEDDATRFAILNNFLDGFR
                     GTVFRQTQFAEFEHAIHQADQNGEVLTSDFLNKLYADLNQEYYGLSKEDNPEIQYEWA
                     RIPHFYYNYYVYQYSTGFAAASALAEKIVHGSQEDRDRYIDYLKAGKSDYPLNVMRKA
                     GVDMEKEDYLNDAFAVFERRLNEFEALVEKLGLA"
     gene            2173..2886
                     /locus_tag="VQ543_001692"
     CDS             2173..2886
                     /locus_tag="VQ543_001692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-methyltransferase"
                     /protein_id="HET2612378.1"
                     /translation="MVESYSKNANHNMRRPVVKEEIVDLMRQRQKQVTGFLKELENFA
                     RKENIPIIPHETVAYFRFLMETMQPKNILEIGTAIGFSALLMAEHAPNAKITTIDRNP
                     EMIGFAKENFAQFDSRKQITLLEGDAVDVLSTLTESYDFVFMDSAKSKYIVFLPEILK
                     HLEVGGVVVLDDIFQGGDVAKDIMEVRRGQRTIYRGLQKLFDATLDNPELTATLVPLG
                     DGILMLRKNVADVQLSESE"
     gene            2953..3894
                     /gene="prsA"
                     /locus_tag="VQ543_001693"
     CDS             2953..3894
                     /gene="prsA"
                     /locus_tag="VQ543_001693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase PrsA"
                     /protein_id="HET2612379.1"
                     /translation="MKKKLLAGAITLLSVATLAACSKGSEGADLISMKGDVITEHQFY
                     EQVKNNPSAQQVLLNMTIQKVFEKQYGSELDDKEVDDTIAEEKKQYGENYQRVLSQAG
                     MTLETRKAQIRTSKLVELAVKKVAEAELTDEAYKKAFDEYTPDVTAQIIRLNNEDKAK
                     EVLEKAKAEGADFAQLAKDNSTDEKTKENGGEITFDSASTEVPEQVKKAAFALDVDGV
                     SDVITATGTQAYSSQYYIVKLTKKTEKSSNIDDYKEKLKTVILTQKQNDSTFVQSIIG
                     KELQAANIKVKDQAFQNIFTQYIGGGDSSSSSSTSNE"
     gene            complement(4011..4352)
                     /locus_tag="VQ543_001694"
                     /pseudo
     CDS             complement(4011..4352)
                     /locus_tag="VQ543_001694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            4765..4860
                     /locus_tag="VQ543_001695"
                     /pseudo
     CDS             4765..4860
                     /locus_tag="VQ543_001695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(5113..5733)
                     /locus_tag="VQ543_001696"
     CDS             complement(5113..5733)
                     /locus_tag="VQ543_001696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HET2612380.1"
                     /translation="MKLYFVRHGRTLWNQEGRFQGASGDSPLLPESIETLKRLGQYLK
                     EIPFDQIYSSDLPRAVKSAEIIQSQLYTPCSLEIVPNLREWQLGKLEGLKIATLEAIY
                     PQQIQAFRSNLAQFDTRMFGAESLYSTTQRTIQFIKSLKDSPAERILIVGHGANLTAS
                     LRTLLGYKEPLLRKDGGLANASLTIIETHDFETFTLNTWNDTSYQS"
     gene            complement(5733..6215)
                     /locus_tag="VQ543_001697"
     CDS             complement(5733..6215)
                     /locus_tag="VQ543_001697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA deacylase"
                     /protein_id="HET2612381.1"
                     /translation="MAKKVKIKKTLVEQILSKAAIPHQGIQINALEGELPQGYERDQI
                     FKTLALLGDKTGPIIGIVPITQHLSEKKLAKISGNKKVSMIPQKDLEKTTGYIHGANN
                     PVGIRQKHNYPIFIDKIALDLDRMIVSAGEVGHSIIVAPQDLASFVKADFVDILEDIK
                     "
     gene            complement(6215..7057)
                     /locus_tag="VQ543_001698"
     CDS             complement(6215..7057)
                     /locus_tag="VQ543_001698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF368 domain-containing protein"
                     /protein_id="HET2612382.1"
                     /translation="MLSWLARVIKGIVIALGFILPGISGGVLAAILGIYERMIGFLAH
                     PFKDLKENVLYFIPVAIGMLLGIGLFSYPIEYLLENYQVFVLWSFAGAIIGTVPSLLK
                     ESTRESDRDKIDLAWLWTTFIISGLGLYALNFVVGTLSASFLNFVLAGALLALGVLVP
                     GLSPSNLLLILGLYAPMLTGFKTFDLLGTFFPIGIGAGATLIVFSKLMDYALNNYHSR
                     VYHFIIGIVLSSTLLILIPNAGNAESIQYTGLSLVGYVIIAFFFALGIWLGIWMSQLE
                     DKYK"
     gene            complement(7152..7952)
                     /locus_tag="VQ543_001699"
     CDS             complement(7152..7952)
                     /locus_tag="VQ543_001699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 25 protein"
                     /protein_id="HET2612383.1"
                     /translation="MRKQIHPLILFSFFGIMMFILIINRPLNDSQSFKTKSNIAQIEA
                     QALKHLDKPIIDLSGWQRPEEINYDALSQNISGAIVRVHSGAQTTKENDASFINGIDK
                     AYKSHITELQKRNVPVAVYAYVAGKSVQEMEKAAEVFYNAASPYSPSYYWLDVEDKTM
                     SNMNEGVENFRAKLASLGAKNIGIYVGVYFMEEHSIDTGKFTSVWIPSYGSDSGFLES
                     SPKTDLDYDIHQYTSKGKIAGFDHDLDINVISPLKNKEETFRKLFLKP"
     gene            8096..9475
                     /gene="glmU"
                     /locus_tag="VQ543_001700"
     CDS             8096..9475
                     /gene="glmU"
                     /locus_tag="VQ543_001700"
                     /EC_number="2.3.1.157"
                     /EC_number="2.7.7.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000073762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional UDP-N-acetylglucosamine
                     diphosphorylase/glucosamine-1-phosphate
                     N-acetyltransferase GlmU"
                     /protein_id="HET2612384.1"
                     /translation="MSNFAIILAAGKGTRMKSDLPKVLHKVAGISMLEHVFRSVGAIQ
                     PEKTVTVVGHKAELVEEVLAGQTEFVTQSEQLGTGHAVMMTEPILEGLSGHTLVIAGD
                     TPLITGESLKNLIDFHINHKNVATILTAETDNPFGYGRIVRNDNAEVLRIVEQKDATD
                     FEKQIKEINTGTYVFDNERLFEALKNINTNNAQGEYYITDVIGIFRETGEKVGAYTLK
                     DFDESLGVNDRVALATAESVMRRRINHKHMVNGVSFVNPEATYIDIDVEIAPEVQIEA
                     NVTLKGQTKIGAETVLTNGTYVVDSTIGAGAVITNSMIEESSVADGVTVGPYAHIRPN
                     SSLGAQVHIGNFVEVKGSSIGENTKAGHLTYIGNCEVGSNVNFGAGTITVNYDGKNKY
                     KTVIGDNVFVGSNSTIIAPVELGDNSLVGAGSTITKDVPADAIAIGRGRQINKDEYAT
                     RLPHHPKNQ"
     gene            9485..10030
                     /locus_tag="VQ543_001701"
     CDS             9485..10030
                     /locus_tag="VQ543_001701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000393791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HET2612385.1"
                     /translation="MEFEEKTLSRKEIYQGPIFKLVQDQVELPEGKGTARRDLIFHNG
                     AVCVLAVTDEQKLILVKQYRKAIEAVSYEIPAGKLEVGENTAPVAAALRELEEETAYT
                     GKLELLYDFYSAIGFCNEKLKLYLASDLTKVENPRPQDEDETLEVLEVSLEEAKELIQ
                     SGHICDAKTIMAVQYWELQKK"
     gene            10042..10356
                     /locus_tag="VQ543_001702"
     CDS             10042..10356
                     /locus_tag="VQ543_001702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="foldase"
                     /protein_id="HET2612386.1"
                     /translation="MGKSLLTDEMIERANRGEKISGPPLLDDNEETKILPTSSSRFGY
                     ANPKDHGFSQETLKIQVEPSIHKSRRIENTKRNVFNSKLNKILFAVIFLLILLVLAMK
                     LL"
     gene            10373..11065
                     /locus_tag="VQ543_001703"
     CDS             10373..11065
                     /locus_tag="VQ543_001703"
                     /EC_number="3.2.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-methylthioadenosine/adenosylhomocysteine
                     nucleosidase"
                     /protein_id="HET2612387.1"
                     /translation="MKIGIIAAMPEELAYLVQHLDNTQEQVVLGNTYHTGTIASHEVV
                     LVESGIGKVMSAMSVAILADHFQVDALINTGSAGAVAEGIAVGDVVIADKLAYHDVDV
                     TAFGYAYGQMAQQPLYFESDKTFVAQIQESLSQLDQNWHLGLIATGDSFVAGNDKIEA
                     IKSHFPEVLAVEMEGAAIAQAAHALNLPVLVIRAMSDNANHEANIFFDEFIIEAGRRS
                     AQVLLTFLKALD"
     gene            11142..11633
                     /gene="rocS"
                     /locus_tag="VQ543_001704"
     CDS             11142..11633
                     /gene="rocS"
                     /locus_tag="VQ543_001704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000021242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein RocS"
                     /protein_id="HET2612388.1"
                     /translation="MSIEMTVSEIAEVLGLSRQAINNRVKELPEEDTDKNDKGVTVVT
                     RSGLIKLEEIYKKTIFEDEPVSEDVKQRELMEILVDEKNAEILRLYEQLKAKDRQLSE
                     KDEQMRIKDRQIAEKDKQLDQQQQLTLQAMKDQENLKLELDQAKEEVQSTKKGFFARL
                     FGG"
     gene            11731..12321
                     /locus_tag="VQ543_001705"
     CDS             11731..12321
                     /locus_tag="VQ543_001705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exonuclease"
                     /protein_id="HET2612389.1"
                     /translation="MERLEDYIAFDLEFNQHEGQTHLIQVSAVRFRDGREIDAYDSYV
                     HTSVPLKSFINGLTGITAETLKDAPPVEKVLEEFQEFVGSLLMIGYNAAKSDLPILAE
                     HGLDYSQQYKVDLYDEAFERRSSDLHGIANLKLQTVASFLGFQGQSHNSLEDARMTAR
                     VYESFLESDQARELLETESSLSNNPFGVLDLSQLFD"
     gene            12330..14093
                     /locus_tag="VQ543_001706"
     CDS             12330..14093
                     /locus_tag="VQ543_001706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000801733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HET2612390.1"
                     /translation="MKPEKPKKLGLKQIYLNLDKILFLFFLIFMIVEYLWVPFNSWLA
                     SFLLDQTGYLFISYNNVLAILTHSPLISLAFLALIVINLLVAYFQIGLLFIGARHLLY
                     NEKRRLIEYIRKVFHESFGFMKKLTCAKALFIFFYIAMLFPFIRKMLKIYYLNKIVIP
                     EFIQAYLEDKYWMWWLSILLLSLIFLYVSVRLMFALPKIVYDQLTVREAVMFSLEKTK
                     KRVTFYAWNLFYILLKAHLLFYLPLIPLLLAQTLVDDITQRESLILGILNFVVIKNLY
                     YMALTYFLVKFVSFLTGKELDMLPRREKDHIVRWGVMTCASLFFALEGYIYLEAPMVH
                     LPQLISHRGVSNANGIQNTVESLETTAQLKPDLVETDVQETKDGQFVMMHDANLKNLA
                     GINKSPQDLNLEELKGIDIFENGYQTKISSFEDYLSRANELGQKLLIEIKTSKKDSPD
                     MMNRFLARYAAKLKIYGHQIQSLDYHVVEKVRQYDAELPVYFIMPYNSVFPKTRATGY
                     TMEYSTLDEYFVSKLWTTDQKLYVWTVNDSEAISKSLHLGVDGVITDDLEKVQREIEV
                     AQEDPEYTDLLLKKALEFFEF"
BASE COUNT         4485 a         2552 c         2969 g         4248 t
ORIGIN      
        1 aaatattgcg tcttccctat aagaaacaaa aaatatctca ttttacagtt tctgaggaca
       61 aggacatctg tcgctatatc cggcaacaac tttattatca aaatctcttt tggatgaaag
      121 aacaagcaga agcctatcaa aagggagaaa atatcctgac ttatggactg aaagaatggt
      181 atccacaaat tcgaccaata gtgggcaaat ttttccagat tgaacaagac ttgactagct
      241 attatcagca cttttatacc tattaccaaa aaaatcctca aaatgattgg caaaagcttt
      301 atccaccagc cttttatcag caatatttct tgaaaaatat ggtagaatag aaaggatgga
      361 ggaatctaat ggtattacaa agaaatgaaa taaatgaaaa agatacatgg gatctatcaa
      421 cgatctaccc aactgaccag gcttgggaag aagtcttaaa agatttaaca gaacaattgg
      481 agacagtagc ccagtatgaa ggccatctct tggatagtgc ggataaccta ctagaaatca
      541 ctgaattttc tcttgaaatg gaacgccaga tggagaagct ttacgtttat gctcatatga
      601 agaatgacca ggatacacgt gaagctaagt atcaagagta ctatgccaag gccatgacat
      661 tctacagcca gttagaccaa gccttttcat tctatgagcc tgaatttatg gagattagcg
      721 aaaagcagta tgctgacttt ttagaagctc aaccaaagct gcaggtttat caacactatt
      781 ttgacaagct cttgcaaggc aaggatcacg ttctctcaca acgtgaagaa gaattattgg
      841 ctggagctgg agaaatcttt ggttcagcaa gtgaaacctt cgctatcttg gacaatgcgg
      901 atattgtgtt cccttatgtc ctagacgatg atggtaaaga agttcagcta tctcatggga
      961 tttacacacg tttgatggag tctaaaaaac gtgaggttcg ccgtggtgcc tatcaagctc
     1021 tttatgcgac ttacgaacaa ttccaacaca cctatgccaa aaccttgcaa accaatgtta
     1081 aggtgcaaaa ttaccgtgct aaagttcgta actacaagag tgctcgtcat gcagccctcg
     1141 cagcgaattt tgttccagaa agtgtttatg acaatttggt agcagcagtt cgcaagcatt
     1201 tgccactctt acatcgctat cttgagcttc gttcaaaaat cttggggatt tcagatctca
     1261 agatgtacga tgtctacaca ccgctttcat ctgttgaata cagttttacc taccaagaag
     1321 ccttgaaaaa agcagaagat gctttggcag tcttgggtga ggattacttg agccgtgtta
     1381 aacgtgcctt cagcgagcgt tggattgatg tttacgaaaa tcaaggcaag cgttcaggtg
     1441 cctactctgg tggttcttac gataccaatg cctttatgct tctcaactgg caggacaatc
     1501 tggacaatct ctttactctt gttcatgaaa caggtcacag tatgcattca agctatactc
     1561 gtgaaactca gccttatgtt tacggagatt actctatctt tttggctgag attgcctcaa
     1621 ctaccaatga aaatatcttg acggagaaat tattggaaga agtggaagac gacgcaacac
     1681 gctttgctat tctcaataac ttcctagatg gtttccgtgg aacagttttc cgccaaactc
     1741 aatttgctga gtttgaacac gccattcacc aagcagatca aaatggggag gtcttgacaa
     1801 gcgatttcct aaataaactc tacgcagact tgaaccaaga gtattatggt ttgagtaagg
     1861 aagacaatcc tgaaatccaa tacgagtggg ctcgcattcc acacttctac tataactact
     1921 atgtatatca atattcaact ggctttgcgg ccgcctcagc cttggctgaa aaaattgtcc
     1981 atggtagtca agaagaccgt gaccgctata tcgactacct caaggcaggt aagtcggact
     2041 atccacttaa tgtcatgaga aaagctggtg ttgatatgga gaaggaagac tacctcaacg
     2101 atgcctttgc agtctttgaa cgccgtttaa atgagtttga agcccttgtt gaaaaattag
     2161 gattggcata aaatggttga atcgtatagt aagaatgcta accataacat gcgtcgtcct
     2221 gtcgtcaaag aagaaattgt agacttgatg cgtcagcgtc aaaagcaggt cacaggtttc
     2281 ttgaaagaat tggaaaactt tgcccgcaag gaaaatattc ctattattcc ccatgaaacg
     2341 gttgcttatt tccgttttct tatggaaacc atgcagccta aaaatattct ggaaattggg
     2401 acggctatcg gtttttcagc tctcttgatg gctgaacatg cgccaaatgc taagattaca
     2461 actattgatc gtaatccaga aatgattggt tttgccaagg aaaattttgc ccagtttgac
     2521 agtcgcaagc aaatcactct cctagaggga gatgcggtgg atgtcttatc tacactgaca
     2581 gagtcttatg atttcgtctt tatggattct gccaagtcta aatacatcgt ctttctgcca
     2641 gaaatcctca aacatttgga agttggtggt gtggttgtct tggatgatat ttttcaaggt
     2701 ggtgatgttg ccaaggatat tatggaagtc cgtcgtggtc agcgaaccat ttatcgaggc
     2761 cttcaaaaat tatttgatgc aaccttagac aatccagaac tcaccgcaac attagtgcct
     2821 ttaggagatg gtattctcat gcttcgtaaa aatgtagcag atgttcaact gtctgaaagc
     2881 gaatgatttt cagaaaaatt taagaaaaaa tagtaaaata gatagagtaa cacttatctc
     2941 aaaggagtag acatgaagaa aaaattattg gcaggtgcca tcacactatt atcagtagca
     3001 actttagcag cttgttcgaa agggtcagaa ggggcagacc ttatcagcat gaaaggggat
     3061 gtcatcacag aacatcaatt ttatgagcaa gtgaaaaaca acccttcagc ccaacaagtc
     3121 ttgttaaata tgaccatcca aaaagttttt gaaaaacaat atggctcaga gcttgatgat
     3181 aaagaggttg atgatactat tgccgaagaa aaaaaacaat atggcgaaaa ctaccaacgt
     3241 gtcttgtcac aagcaggtat gactcttgaa acacgtaaag ctcaaattcg tacaagtaaa
     3301 ttagttgagt tggcagttaa gaaggtagca gaagctgaat tgacagatga agcctataag
     3361 aaagcctttg atgagtacac tccagatgta acggctcaaa tcatccgtct taataatgaa
     3421 gataaggcca aagaagttct cgaaaaagcc aaggcagaag gtgctgattt tgctcaatta
     3481 gccaaagata attcaactga tgaaaaaaca aaagaaaatg gtggagaaat tacctttgat
     3541 tctgcttcaa cagaagtacc tgagcaagtc aaaaaagccg ctttcgcttt agatgtggat
     3601 ggtgtttctg atgtgattac agcaactggc acacaagcct acagtagcca atattacatt
     3661 gtaaaactca ctaagaaaac agaaaaatca tctaatattg atgactacaa agaaaaatta
     3721 aaaactgtta tcttgactca aaaacaaaat gattcaacat ttgttcaaag cattatcgga
     3781 aaagaattgc aagcagccaa tatcaaggtt aaggaccaag ccttccaaaa tatctttacc
     3841 caatatatcg gtggtggaga ttcaagctca agcagtagta catcaaacga atagtccaaa
     3901 tcaatgagtc agggaaaaaa actcgacttc aggaaaaaat gaagcaaaca ttcccacaat
     3961 aaaacgcata gtacaaggtt tgtactgacc ccaaaagtta gacaattaat ttatctgaag
     4021 gatttagttc tgtattgcac agggctaagt ccttttagtt ttaccttaat tctcttattg
     4081 ttgtaataat caatatagtc tataatggct tgttccaatt gattaagtga tttaaatgtt
     4141 ttctcatagc cataaaacat ttcggatttt aaaatgccaa agaaagattc catcctaccg
     4201 ttgtcttggc tgtttccttt gcgtgacata gatgcttgaa ttcccttact ctctaggaag
     4261 cgatgataag aatcgtgttg gtattgccag ccttggtcac tatggagaat cgtattctcg
     4321 tagtgcttct ctttgaatgc ctgttccaac attaacgatc aatcaattta atcatgtacc
     4381 taatattaga attgtttatc ccaaatttat ttgaaagctt ctctaagcta tatccttgtt
     4441 ttctaagttc atagatctga actttatcat cataagttaa tttcataata aaaacacccc
     4501 aaaagttaga ttttttctgt ctaacttttg gggtgtagtt catgtacacc tgatatgatg
     4561 cgttttataa ttttaaagac tttttgacca gcctcatttt tttaacttga tactcagtga
     4621 aaagcaaaga ttaaactagg aagctagctg taggctgctc aaagaacagc tttgaggttg
     4681 cagataaaac ttgtgaggtc accaacatat ataatgtgaa gctgacgtga cttgaataga
     4741 ttttagaagg gtatgagtct ggaagtttta atggataatg caagattcca tagaatgggt
     4801 aagctagagt tcttatgtga agagtttggg cataaacttt taccttttcc tccctactca
     4861 tcttagtata gaaaagtgaa tctaaaatag tacataactg cttctaaaac attcttataa
     4921 attgatttaa attctcaaat catattattc agttcttatt tcattttgct ctacaatcct
     4981 gttgagaaga cacgtgttca tatcaaaaag gtattggcaa gttgcaatac ctttttacaa
     5041 ggttcttttg tcttattttt gtttcaactg actatatctc ctatggttct agttcagaag
     5101 gctaggctat aattatgatt gataagaagt atcattccaa gtattgagag tgaatgtttc
     5161 aaaatcatgg gtttctataa tggtcaggct ggcatttgct agaccgccat ctttacgaag
     5221 aagtggttct ttatagccta ggagagtacg aagactggca gtaagattgg cgccgtgtcc
     5281 gacaattaga atacgctcag ctggactatc ttttaatgat ttgataaatt ggatggtccg
     5341 ttgagttgta ctatagaggg attcggctcc gaacattcga gtgtcaaatt gagcaagatt
     5401 tgaacgaaaa gcctggattt gttgcgggta aatagcttcc aaggttgcaa ttttcaaacc
     5461 ttctaacttc ccaagttgcc attcacggag attaggaacg atttctaaag aacagggggt
     5521 atagagttga ctttggataa tctcagcaga tttgaccgct cgaggtaaat cacttgaata
     5581 aatctgatca aaaggaattt ccttgagata ctggccaagt cgttttaggg tttcaatgga
     5641 ttcaggaaga agaggagaat caccgctagc accttgaaaa cgaccttctt ggttccagag
     5701 ggtacgaccg tggcggacaa agtagagttt cattacttga tgtcctccaa aatatctaca
     5761 aagtctgcct ttacaaagct agccaagtct tgtggcgcga cgataatgct gtgtccgact
     5821 tcgcctgcag agacaatcat tcgatccaaa tctagagcaa ttttatcgat aaaaatggga
     5881 taattgtgtt tctgacgaat tccgacagga ttattggctc catgaatgta accagttgtt
     5941 ttttctaagt ccttttgtgg aatcatgctc acttttttat tgccagaaat tttagctagt
     6001 ttcttttcag acaagtgctg agtgataggg acaattccga taatcggtcc ggtcttgtct
     6061 cccaaaagcg ccaaggtttt gaaaatctga tctcgttcat aaccttgagg aagctctcct
     6121 tctagggcat tgatttgaat cccctgatga gggatagctg ctttagatag gatttgttcc
     6181 accaatgttt ttttgatttt aacttttttt gccattattt atatttatcc tccaattgac
     6241 tcatccaaat accaagccag attcccagcg caaagaagaa ggcgatgatg acataaccga
     6301 caagtgaaag tcctgtgtat tggatacttt cagcgtttcc tgcatttgga attaagatca
     6361 aaagggtact tgataggacg ataccgatga tgaaatgata gacgcgtgag tggtagttgt
     6421 ttaaggcata atccatcaat tttgaaaaaa cgatgagagt tgcacctgca ccaattccaa
     6481 tcggaaagaa ggttcccaag agatcaaaag ttttaaaacc agtcaacata ggagcataga
     6541 gtcccaaaat caaaagtaag ttcgatgggc tgaggccagg aaccaagacg ccaagggcca
     6601 atagtgcgcc tgctaggacg aagttaagaa agctggcgct taaggttcca acgacaaaat
     6661 ttaaggcata gagtcctaat ccagaaatga taaaggttgt ccataaccaa gctaaatcaa
     6721 tcttgtctcg gtcagattct cgagttgatt ctttgaggag gctaggaact gtaccgataa
     6781 tagctcccgc aaagctccat aatacaaaga cctgataatt ttcaagcagg tattcaatcg
     6841 ggtaggaaaa taagccgatt cccagaagca taccgatggc aactggaata aagtacaaaa
     6901 cattttcttt aaggtcttta aagggatggg ccagaaagcc aatcattcgt tcatagattc
     6961 ctaagattgc tgctagaacc cctccggaaa ttcccggtag gataaatcca agagcaatta
     7021 caatcccttt aataacgcgt gctaaccatg agagcatata tttcctccaa ctatttctat
     7081 ttcaaaaatt ccttactata ttgtatcaca atcagacaca aaaagaaaaa gcaaatgata
     7141 aacaaatgct tttaaggttt taaaaaaagt tttcgaaagg tttcttcttt attttttaag
     7201 ggagagataa cgttgatatc taaatcgtgg tcaaagccgg caatttttcc tttagatgtg
     7261 tattggtgaa tatcataatc taaatcagtt ttaggactgc tctccaaaaa tcctgagtct
     7321 gagccgtagg acggaatcca aacagaggta aacttgcctg tatcaatact gtgttcttcc
     7381 atgaagtaga caccaacgta gatgccgatg tttttagcac ctagtgatgc tagttttgct
     7441 cgaaagtttt cgacaccttc gttcatatta gacatggttt tgtcttccac gtcaagccaa
     7501 tagtaactag ggctgtaagg agaggcagca ttgtagaaaa cttcggcagc cttttccatt
     7561 tcttggacac tttttccagc tacataagcg tagacagcaa ctgggacatt ccgcttttga
     7621 agttcagtga tatgactctt ataggccttg tctattccat tgataaatga agcatcattt
     7681 tcttttgttg tttgagcacc actgtgaaca cgaacaatag cacctgaaat attttgtgag
     7741 agggcatcgt agttgatttc ctcaggacgc tgccagccag agaggtcaat aatcggtttg
     7801 tctaagtgtt tcaaagcctg tgcttcaatc tgtgctatat tggattttgt tttaaacgat
     7861 tggctgtcat taagtgggcg attgatgatt aaaatgaaca tcataatccc aaaaaaacta
     7921 aataaaataa gtggatgaat ttgttttctc atatcttata agtctaccct aaaaatcaaa
     7981 aaaaatcaaa aaaatgggtt aaggaagaga ctttagagca ttttttcatt caagagtgcg
     8041 gaatgatttg aaatatggta taataaaagg gaatttctac agaaaagaga agattatgtc
     8101 aaattttgcc attattttag cagcgggtaa agggactcgc atgaaatctg atttgccaaa
     8161 agttttgcac aaggttgcgg gtatttctat gttggaacat gttttccgta gtgtgggagc
     8221 tatccaacct gaaaagacag taacagttgt aggacacaag gcagaattgg ttgaggaggt
     8281 cttggctgga cagacagaat ttgtgactca atctgaacag ttgggaactg gtcatgcagt
     8341 tatgatgaca gaacctatct tagaaggttt gtcaggacac accttggtca ttgcaggaga
     8401 tactccttta atcactggtg aaagcttgaa aaacttgatt gatttccata tcaatcataa
     8461 aaatgtggcc actatcttga ctgctgaaac ggataatcct tttggctatg gacgaattgt
     8521 tcgtaatgac aatgctgagg ttcttcgtat tgttgagcag aaggatgcta cagattttga
     8581 aaagcaaatc aaggaaatca acactggaac atacgtcttt gacaacgagc gtttgtttga
     8641 ggctttgaaa aatatcaata ccaataacgc tcaaggcgaa tactatatta cagacgtcat
     8701 tggtattttc cgtgaaactg gtgaaaaagt tggcgcttat actttgaaag attttgatga
     8761 aagtcttggg gtaaatgacc gtgtggcgct tgcgacagct gagtcagtta tgcgtcgtcg
     8821 catcaatcat aaacacatgg tcaacggtgt tagctttgtc aatccagaag caacttatat
     8881 cgatattgat gttgagattg ctccggaagt tcaaatcgaa gccaatgtta ccttgaaagg
     8941 gcaaacgaaa attggtgctg agactgtttt gacaaacggt acttatgtag tggacagcac
     9001 tatcggagca ggagcggtca ttaccaattc tatgattgag gaaagtagtg ttgcagacgg
     9061 tgtgacagtc ggtccttatg ctcacattcg tccaaattca agtctgggtg cccaagttca
     9121 tattggtaac tttgttgagg tgaaaggatc ttcaatcggt gagaatacca aggctggtca
     9181 tttgacttat atcggaaact gtgaagtggg aagcaacgtt aatttcggtg ctggaactat
     9241 tacagtcaac tatgacggca aaaacaaata caagacagtc attggagaca atgtctttgt
     9301 tggttcaaat tcaaccatta ttgcaccagt agaacttggt gacaattccc tcgttggtgc
     9361 tggttcaact attactaaag acgtgccagc agatgctatt gctattggtc gcggtcgtca
     9421 gatcaataaa gacgaatatg caacacgtct tcctcatcat cctaagaacc agtaggagcc
     9481 tatcatggag tttgaagaaa aaacgcttag ccgaaaagaa atctatcaag gaccaatatt
     9541 taaactggtc caagatcagg ttgaattacc agaaggcaag ggaactgccc gacgggattt
     9601 gattttccac aatggggctg tctgtgtttt agcagtaacg gatgaacaaa aacttatctt
     9661 ggtcaagcag taccgcaaag ctatcgaggc tgtctcttac gaaattccag ccggaaaatt
     9721 ggaagtagga gaaaacacag cccctgtggc agctgccctt cgtgaattag aggaagaaac
     9781 agcctataca gggaaattag aactcttgta cgatttttat tcagctattg gcttttgtaa
     9841 tgagaagtta aaactatatt tagcaagcga tttgacaaaa gtggaaaatc cgcgtccgca
     9901 ggatgaggat gaaaccttgg aagtccttga agtgagctta gaagaagcga aagaattaat
     9961 ccaatcaggt catatctgtg atgccaagac aattatggct gttcagtatt gggagttgca
    10021 gaaaaaatag aggaggtcag tatgggtaaa tctttattaa cggatgaaat gattgaaaga
    10081 gctaatagag gcgaaaaaat ttcaggtcct cctttgctag atgataatga ggaaactaag
    10141 attttaccaa cctcttcttc ccgttttggt tatgccaatc ctaaggatca tggttttagc
    10201 caggaaacct tgaagattca ggtcgaacca tctattcata aaagccgtcg tattgaaaat
    10261 accaagagaa atgtcttcaa ttctaagttg aataaaatct tatttgcggt catctttctc
    10321 ttgattttgc ttgttttagc aatgaaactt ttgtaataga aaaggaattg aaatgaaaat
    10381 aggaattatt gctgctatgc cagaagaact ggcttatctg gtccagcatt tagataatac
    10441 ccaggagcaa gttgttttgg ggaataccta tcatacagga accattgctt ctcatgaagt
    10501 cgttcttgta gaaagtggaa ttggtaaggt catgtctgct atgagtgtgg cgattttggc
    10561 tgatcatttc caggtggatg cccttattaa tacgggttca gctggggcag tagcagaagg
    10621 tatcgctgtt ggggatgtcg tgattgctga caaattagcc tatcatgacg tggatgtcac
    10681 agcttttggc tatgcttatg gacaaatggc gcaacaaccg ctttatttcg aatcagacaa
    10741 aacctttgtt gctcaaatcc aagagagttt atctcaattg gaccaaaact ggcatcttgg
    10801 tttgattgct acaggagata gttttgttgc aggaaatgac aagatagaag cgattaagtc
    10861 ccatttccca gaagttttag ccgtggagat ggagggggca gctattgctc aagcagcgca
    10921 tgccctcaat ctcccagtct tagtcatcag agctatgagt gacaatgcca accatgaagc
    10981 aaacatcttt tttgatgagt ttattatcga agctggacgt cgctctgccc aagtcttgtt
    11041 gacctttttg aaggctttag attaagcgga aatttgacag tttttctagc ttatgataag
    11101 atttaagtaa agaaaagcta gaaaacgttt cagaggatat tatgagtatt gaaatgaccg
    11161 tcagtgagat tgcagaggtc ttaggattat ctcgccaagc aatcaataac cgtgtcaaag
    11221 aattaccaga agaagacaca gataaaaatg acaaaggggt aacagttgtt accagaagtg
    11281 gcttgattaa gctagaagaa atctataaaa aaacgatttt tgaagatgag cctgtcagtg
    11341 aagatgtcaa acaacgtgaa ctgatggaga ttctagtgga tgagaagaat gcagaaattc
    11401 ttcgtcttta tgaacaatta aaagccaagg atcgtcagtt atcagaaaaa gacgagcaga
    11461 tgcgtatcaa agaccgtcag attgctgaga aagacaaaca attagatcag caacaacaat
    11521 tgacccttca agccatgaag gatcaagaaa atcttaagct agagctggac caagcaaaag
    11581 aagaagtcca atccactaag aaaggctttt ttgctcgttt atttggagga taatcaagga
    11641 gctgtttagg ttaaatgcta acctgatggc ttcttttgtt tgtgaatagt atagttgatt
    11701 agaacagaga cagtagagga gaggtacaga atggaacgat tagaagatta cattgctttt
    11761 gacttagaat ttaatcagca cgaaggacaa acacacttga ttcaagtatc ggcagtgcgt
    11821 tttagagatg gtcgggaaat cgatgcctat gattcctatg ttcataccag cgtccctcta
    11881 aaaagcttta tcaatggttt gaccgggatt acagctgaga ccttaaaaga tgctcctcca
    11941 gttgagaaag tcttagaaga attccaagag tttgtgggtt ctttgctgat gataggctac
    12001 aatgctgcta aaagtgattt acctatttta gcagagcatg gtttagacta tagccaacag
    12061 tacaaggtgg atttgtatga tgaagctttt gaacgtcgga gttcagattt acatggtatt
    12121 gccaatctca aattgcaaac tgttgcctca tttcttggat ttcaaggtca gtctcataat
    12181 agtttagagg atgctcggat gacggcgcgt gtttacgaat ccttcttaga gtcggatcaa
    12241 gctagggaat tgttagagac agaaagtagc ttatcaaaca atccttttgg tgtcttggac
    12301 ttgtctcaat tatttgacta ggagtgccta tgaaacctga aaaacctaaa aaattgggtc
    12361 ttaaacagat ttacctcaat cttgataaaa tcctctttct atttttcttg atttttatga
    12421 tagtggagta tttgtgggta ccattcaatt catggttggc tagcttctta ttagatcaga
    12481 caggttatct ttttatttcc tataacaatg tcttagccat ccttactcat tctccattga
    12541 ttagtctagc ttttttagcc ttgattgtaa ttaaccttct ggttgcttat tttcaaatag
    12601 gactcctctt tattggtgct cgtcatctcc tctataatga aaagcgaagg ctaattgagt
    12661 atatccgcaa ggttttccat gaaagttttg gatttatgaa aaagctaact tgcgctaaag
    12721 ccttgtttat ctttttctat atagctatgc tttttccttt tatacggaaa atgctgaaga
    12781 tttattatct taataaaatc gtcattccag agtttatcca agcttattta gaagataaat
    12841 attggatgtg gtggctgagc atcctacttc tatctcttat ctttctctat gtctctgtca
    12901 gattgatgtt tgcccttccg aagattgtat atgatcagct gactgttcga gaagcagtga
    12961 tgtttagctt ggagaaaacc aagaagagag ttacttttta tgcttggaat ttattttaca
    13021 tcttgctcaa agcacattta ttattttatc ttcctttgat tcctttatta ttggctcaaa
    13081 ctttggtaga tgatatcact cagagagagt ctctgattct tggtattttg aattttgtcg
    13141 tgattaaaaa tctctattat atggctctga cttatttttt ggttaaattt gtttcatttt
    13201 tgacaggaaa ggagctggat atgcttccta ggagagaaaa agatcacatc gtgcgatggg
    13261 gtgtcatgac ttgtgccagt cttttctttg ccttagaagg ttatatttat ctggaggctc
    13321 ccatggttca tctacctcaa cttatttctc accgaggggt ttccaatgca aatgggattc
    13381 aaaatacagt agagtccttg gaaactacag cacaactcaa accagacttg gtggagacgg
    13441 acgtgcagga aacaaaagat gggcagtttg tcatgatgca tgatgctaac ttgaaaaatc
    13501 tagcaggtat caataaaagt cctcaagact taaacttgga ggagcttaaa gggattgata
    13561 tttttgaaaa tggctaccag actaaaattt caagctttga agattatctc agtcgagcca
    13621 acgaacttgg tcaaaaatta ctaattgaaa ttaaaaccag taaaaaagat agtccagaca
    13681 tgatgaaccg ctttttagcc cgttatgctg caaagctcaa gatttatgga catcaaatcc
    13741 agtctttaga ctaccatgtt gtcgaaaaag taagacagta tgatgccgaa ctgccagttt
    13801 atttcatcat gccctacaat tctgtctttc ctaaaacaag agcgacagga tatactatgg
    13861 agtactcaac cttggatgaa tattttgtaa gcaaactatg gacaacggat cagaaacttt
    13921 atgtctggac tgtcaatgat tcagaagcta tcagcaaatc tcttcactta ggagtagatg
    13981 gagtgattac agatgatttg gaaaaagttc agcgggaaat agaagtagcc caagaagatc
    14041 cagaatatac ggatttgctc ttgaaaaaag cattggaatt ctttgaattt tagtaataaa
    14101 aaagaggaac ggttgttcct cccatgatag gtaagtattc ttgtgaatgc ttgctttttt
    14161 gtggttgcaa tccgtttacg agaattgttt gtattgttct tgtttcaatt tactttatag
    14221 tgctttgaag ttggaatgct acactataac ttct
//
LOCUS       DAVBEO010000051        14236 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 009
            SAMEA1678075-rid20185393.denovo.051, whole genome shotgun sequence.
ACCESSION   DAVBEO010000051 DAVBEO010000000
VERSION     DAVBEO010000051.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678075
            Sequence Read Archive: ERR226392
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 14236)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14236)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980207.1
            Genome Coverage       :: 150x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:50:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 72 of 147
            Pseudo Genes (incomplete)         :: 72 of 147
            Pseudo Genes (internal stop)      :: 42 of 147
            Pseudo Genes (multiple problems)  :: 32 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14236
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678075-rid20185393.denovo.051"
                     /strain="KS 009"
                     /db_xref="taxon:1313"
     gene            complement(159..1085)
                     /locus_tag="VQ543_001707"
     CDS             complement(159..1085)
                     /locus_tag="VQ543_001707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET2612391.1"
                     /translation="MISRFFRHLFEALKSLKRNGWMTVAAVSSVMITLTLVAIFASVI
                     FNTAKLATDIENNVRVVVYIRKDVEDNSQTIEKEGQTVTNNDYHKVYDSLKNMSTVKS
                     VTFSSKEEQYEKLTEIMGDNWKIFEGDANPLYDAYIVEANTPNDVKTIAEDAKKIEGV
                     SEVQDGGANTERLFKLASFIRVWGLGIAALLIFIAVFLISNTIRITIISRSREIQIMR
                     LVGAKNSYIRGPFLLEGAFIGLLGAIAPSVLVFIVYQIVYQSVNKSLVGQNLSMISPD
                     LFSPLMIALLFVIGVFIGSLGSGISMRRFLKI"
     gene            complement(1078..1770)
                     /gene="ftsE"
                     /locus_tag="VQ543_001708"
     CDS             complement(1078..1770)
                     /gene="ftsE"
                     /locus_tag="VQ543_001708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012130521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division ATP-binding protein FtsE"
                     /protein_id="HET2612392.1"
                     /translation="MSIIEMRDVVKKYDNGTTALRGVSVSVQPGEFAYIVGPSGAGKS
                     TFIRSLYREVKIDKGSLSVAGFNLVKIKKKDVPLLRRSVGVVFQDYKLLPKKTVYENI
                     AYAMEVIGENRRNIKRRVMEVLDLVGLKHKVRSFPNELSGGEQQRIAIARAIVNNPKV
                     LIADEPTGNLDPDNSWEIMNLLERINLQGTTILMATHNSQIVNTLRHRVIAIENGRVV
                     RDESKGEYGYDD"
     gene            complement(1788..2883)
                     /gene="prfB"
                     /locus_tag="VQ543_001709"
     CDS             complement(join(1788..2810,2812..2883))
                     /gene="prfB"
                     /locus_tag="VQ543_001709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511312.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 2"
                     /protein_id="HET2612393.1"
                     /translation="MDISVIRQKIDANREKLASFRGSLDLEGLEEEIAILENKMTEPD
                     FWNDNIAAQKTSQELNELKNTYNTFHKMEELQDEVEILLDFLAEDESVHDELVAQLAE
                     LDKIMTSYEMTLLLSEPYDHNNAILEIHPGSGGTEAQDWGDMLLRMYTRYGNAKGFKV
                     EVLDYQAGDEAGIKSVTLSFEGPNAYGLLKSEMGVHRLVRISPFDSAKRRHTSFTSVE
                     VMPELDDTIEVEIREDDIKMDTFRSGGAGGQNVNKVSTGVRLTHIPTGIVVQSTVDRT
                     QYGNRDRAMKMLQAKLYQMEQDKKAAEVDSLKGEKKEITWGSQIRSYVFTPYTMVKDH
                     RTSFEVAQVDKVMDGDLDGFIDAYLKWRIS"
     gene            complement(2991..3647)
                     /locus_tag="VQ543_001710"
     CDS             complement(2991..3647)
                     /locus_tag="VQ543_001710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HET2612394.1"
                     /translation="MAVKDFMTRKVVYISPDTTVSHAADLMREQGLHRLPVIENDQLV
                     GLVTEGTIAQASPSKATSLSIYEMNYLLNKTKVKDVMIRDVVTVSGYASLEDATYLML
                     KNKIGILPVVDNHQVYGVITDRDVFQAFLEIAGYGEEGIRVRFVTEDEVGVLGKIVSL
                     IVEENLNISHTVNIPRKDGKVIIEVQIDESIDLPALREKFEANGIQVEEIARTSAKVL
                     "
     gene            complement(4112..4822)
                     /locus_tag="VQ543_001711"
     CDS             complement(4112..4822)
                     /locus_tag="VQ543_001711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000062217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2612395.1"
                     /translation="MSMLKVENLSVHYGMIQAVRDVSFEVNEGEVVSLIGANGAGKTT
                     ILRTLSGLVRPSSGKIEFLGQEIQKIPAQKIVAGGLSQVPEGRHVFPGLTVMENLEMG
                     AFLKKNREENQANLKKVFSRFPRLEERKNQDAATLSGGEQQMLAMGRALMSTPKLLLL
                     DEPSMGLAPIFIQEIFDIIQDIQKQGTTVLLIEQNANKALAISDRGYVLETGKIVLSG
                     TGKELASSEEVRKAYLGG"
     gene            complement(4822..5586)
                     /locus_tag="VQ543_001712"
     CDS             complement(4822..5586)
                     /locus_tag="VQ543_001712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002913097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2612396.1"
                     /translation="MALLEVKQLTKHFGGLTAVGDVTLELNEGELVGLIGPNGAGKTT
                     LFNLLTGVYEPSEGTVTLDGHLLNGKSPYKIASLGLGRTFQNIRLFKDLTVLDNVLIA
                     FGNHHKQHVFTSFLRLPAFYKSEKELKAKALELLKIFDLDGDAETLAKNLSYGQQRRL
                     EIVRALATEPKILFLDEPAAGMNPQETAELTELIRRIKDEFKITIMLIEHDMNLVMEV
                     TERIYVLEYGRLIAQGTPDEIKTNKRVIEAYLGGEA"
     gene            complement(5586..6542)
                     /locus_tag="VQ543_001713"
     CDS             complement(5586..6542)
                     /locus_tag="VQ543_001713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid ABC transporter
                     permease"
                     /protein_id="HET2612397.1"
                     /translation="MKENLKVNILWLLLLLAGYSLISVLVSVGVLNLFYVQILQQIGI
                     NIILAVGLNLIVGFSGQFSLGHAGFMAIGAYAAAIIGSKLPTYGAFFGAMLVGALLSG
                     AVALLVGIPTLRLKGDYLAVATLGVSEIIRIFIINGGSLTNGAAGILGIPNFTTWQMV
                     YFFVVITTIATLNFLRSPIGRSTLSVREDEIAAESVGVNTTKIKIIAFVFGAITASIA
                     GSLQAGFIGSVVPKDYTFINSINVLIIVVFGGLGSITGAIVSAIVLGILNMLLQDVAS
                     VRMIIYALALVLVMIFRPGGLLGTWELSLSRFFKKSKKEEQN"
     gene            complement(6546..7415)
                     /locus_tag="VQ543_001714"
     CDS             complement(6546..7415)
                     /locus_tag="VQ543_001714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid ABC transporter
                     permease"
                     /protein_id="HET2612398.1"
                     /translation="MLQQLVNGLILGSVYALLALGYTMVYGIIKLINFAHGDIYMMGA
                     FIGYFLINSFQMNFFVALIVAMLATAILGVVIEFLAYRPLRHSTRIAVLITAIGVSFL
                     LEYGMVYLVGANTRAFPQAIQTVRYDLGPISLTNVQLMILAISLILMILLQVIVQKTK
                     MGKAMRAVSVDSDAAQLMGINVNRTISFTFALGSALAGAAGVLIALYYNSLEPLMGVT
                     PGLKSFVAAVLGGIGIIPGAALGGFVIGLLETFATAFGMSDFRDAIVYGILLLILIVR
                     PAGILGKNVKEKV"
     gene            complement(7683..8843)
                     /locus_tag="VQ543_001715"
     CDS             complement(7683..8843)
                     /locus_tag="VQ543_001715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HET2612399.1"
                     /translation="MKKKFALSFVALASVALLAACVEVKSGAVNTAGNSVEEKTIKIG
                     FNFEESGSLAAYGTAEQKGAQLAVDEINAAGGIDGKQIEVVDKDNKSETAEAASVTTN
                     LVTQSKVSAVVGPATSGATAAAVANATKAGVPLISPSATQDGLTKGQDYLFIGTFQDS
                     FQGKIISNYVSEKLNAKKVVLYTDNASDYAKGIAKSFRESYKGEIVADETFVAGDTDF
                     QAALTNMKGKDFDAIVVPGYYNEAGKIVNQARGMGIDKPIVGGDGFNGEEFVQQATAE
                     KASNIYFISGFSTTVEVSAKAKAFLDAYRAKYNEEPSTFAALAYDSVHLVANAAKGAK
                     NSGEIKDNLAKTKDFEGVTGQTSFDADHNTVKTAYMMTMNNGKVEAAEVVKP"
     gene            complement(8944..9192)
                     /locus_tag="VQ543_001716"
     CDS             complement(8944..9192)
                     /locus_tag="VQ543_001716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000462128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbG family protein"
                     /protein_id="HET2612400.1"
                     /translation="MFEKVNRSGLIIYLYYNRDAKKLQDYGDITYHSKKHRYLQLYVP
                     TQEVEQLVGRLSKEKFIKKVRVCHIQELETPFVGNLYR"
     gene            complement(9271..9861)
                     /gene="clpP"
                     /locus_tag="VQ543_001717"
     CDS             complement(9271..9861)
                     /gene="clpP"
                     /locus_tag="VQ543_001717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease proteolytic subunit
                     ClpP"
                     /protein_id="HET2612401.1"
                     /translation="MIPVVIEQTSRGERSYDIYSRLLKDRIIMLTGPVEDNMANSVIA
                     QLLFLDAQDSTKDIYLYVNTPGGSVSAGLAIVDTMNFIKADVQTIVMGMAASMGTVIA
                     SSGAKGKRFMLPNAEYMIHQPMGGTGGGTQQTDMAIAAEHLLKTRNTLEKILAENSGQ
                     SMEKVHADAERDNWMSAQETLEYGFIDEIMANNSLN"
     gene            complement(10035..10664)
                     /gene="upp"
                     /locus_tag="VQ543_001718"
     CDS             complement(10035..10664)
                     /gene="upp"
                     /locus_tag="VQ543_001718"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002883819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil phosphoribosyltransferase"
                     /protein_id="HET2612402.1"
                     /translation="MGKIEVINHPLIQHKLSILRRTDTSTKAFRELVDEIAMLMGYEV
                     LRDLPLEDVEIETPITKTVQKQLAGKKLAIVPILRAGIGMVDGLLSLVPAAKVGHIGM
                     YRDEETFQPVEYLVKLPEDIDQRQIFVVDPMLATGGSAILAVDSLKKRGASNIKFVCL
                     VSAPEGVKALQEAHPDVEIFTAALDERLNEHGYIVPGLGDAGDRLFGTK"
     gene            complement(10753..11220)
                     /locus_tag="VQ543_001719"
     CDS             complement(10753..11220)
                     /locus_tag="VQ543_001719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000138511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine/deoxycytidylate deaminase family
                     protein"
                     /protein_id="HET2612403.1"
                     /translation="MTEKRLAWDEYFAAQALLIANRSTCKRAKVGAILVKDNKVISTG
                     YNGSVSGTEHCIDHECLVIEGHCVRTLHAEVNAILQGAERGVPKGFTAYVTHFPCLNC
                     TKQLLQVGCKRVVYINQYRMDDYAQYLYQEKGTELTHLPLETVQTALKEADLM"
     gene            complement(11239..11796)
                     /locus_tag="VQ543_001720"
     CDS             complement(11239..11796)
                     /locus_tag="VQ543_001720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000003900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HET2612404.1"
                     /translation="MSERRISEKSLENLRKSNQESNLLTREAIETALLQLLEKKELTK
                     ISISELVKRAGVSRAAFYRNYDSKEEILESVFKRTVHNIMEQLHHYDLKTDLYLVWVH
                     LFREARKEARVIQLALDYHLEKIFVQAMQEFLEKYHGKSKGVSSYLHSFWSSAIVSVL
                     LKWIKDGMKVPAEKIADLGLPFFKK"
     gene            11921..12766
                     /locus_tag="VQ543_001721"
     CDS             11921..12766
                     /locus_tag="VQ543_001721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HET2612405.1"
                     /translation="MTWKIIADSGCDYRQLPTPAINTTFVSVPLTIQVADQVFVDDAS
                     LDIDQMMETMYATAEASKSACPSPDDYLRAFEGAKNIFLVTITGTLSGSHNSAQLAKN
                     IYLEDHPDTKIHVIDSLSAGGEVDLLVEKLNDLIDQGLSFEEVVEAITAYQEKTKLLF
                     VLAKVDNLVKNGRLSKLIGTVVGLLNIRMVGKASETGTLELLQKARGSKKSVQAAYDE
                     LVKAGYAGGRIVMAQRNNEKCCQQLSERIRETFPQADIKILPTSGLCSFYAEDGGLLM
                     GYEID"
     gene            12825..13997
                     /locus_tag="VQ543_001722"
     CDS             12825..13997
                     /locus_tag="VQ543_001722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000680052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HET2612406.1"
                     /translation="MKHFDTIVIGGGPAGMMATISSSFYGQKTLLIEKNRKLGKKLAG
                     TGGGRCNVTNNGSLDNLLAGIPGNGRFLYSVFSQFDNHDIINFFTENGVKLKVEDHGR
                     VFPASDKSRTIIEALEKKITELGGQVATQIEIVSVKKVDDQFVLKSADQTFTCEKLIV
                     TTGGKSYPSTGSTGFGHEIARHFKHTITDLEAAESPLLTDFPHKALQGISLDDVTLSY
                     GKHVITHDLLFTHFGLSGPAALRMSSFVKGGEVLSLDVLPQLSEKDLVTFLEENREKS
                     LKNALKTLLPERLAEFFVQGYPEKVKQLTEKEREQLVQSIKELKIPVTGKMSLAKSFV
                     TKGGVSLKEINPKTLESKLVPGLHFAGEVMDINAHTGGFNITSALCTGWVAGSNPI"
     gene            14048..>14236
                     /locus_tag="VQ543_001723"
     CDS             14048..>14236
                     /locus_tag="VQ543_001723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1697 domain-containing protein"
                     /protein_id="HET2612407.1"
                     /translation="MEHIILLRGVTPNGKNAIPKMSYLVDILTEADFQQVRTYIQSGN
                     IILESNLALEEIREQVHTL"
BASE COUNT         4231 a         3092 c         2607 g         4306 t
ORIGIN      
        1 aatttctagt gcgccaaatt tcaagttcaa attagccatc aagaagtctt ctctggggga
       61 cttctttgga agctcttttc ttctacgcat ctcttttcaa aaactcttgt agcaaaaaag
      121 gagattttac aatctcctca taaaagcagc tattttacct aaatcttcaa gaatcggcgc
      181 atggatattc ctgatcccaa tgaaccaatg aaaaccccaa tcacaaatag tagggcaatc
      241 atcaacggac taaataaatc tggactaatc atggatagat tttgccctac caacgatttg
      301 ttgacagatt ggtaaacaat ttgataaaca ataaagacca aaacagatgg tgcgatagct
      361 cccaataaac cgataaaggc tccttctaac aagaacggtc cacggatata actgttttta
      421 gctccaacca agcgcatgat ttgaatttcg cgactgcggg aaataatggt aatacgaatg
      481 gtatttgaaa tcaagaaaac tgcgataaaa attaacaaag cagcaatccc tagtccccaa
      541 acacggataa atgaagctaa cttgaagagt ctttctgtat tggcaccgcc atcttgaacc
      601 tcagagacac cttcaatttt tttagcatct tcggctatag tttttacatc atttggagtg
      661 tttgcctcta caatataggc atcatagaga ggattggcat ctccttcaaa gattttccag
      721 ttatctccca ttatctcggt taatttttca tattgttctt ctttacttga aaaggtaaca
      781 cttttaaccg tagacatgtt cttcaaagaa tcatatacct tgtggtagtc attatttgta
      841 acagtttgac cttctttttc aattgtctga ctattatctt ccacatcctt tcggatataa
      901 actactacac ggacattatt ttcaatatct gtagctagtt tcgctgtatt gaaaataaca
      961 gatgcaaata ttgccaccaa ggtcaaagta atcatgactg aactgacagc agctactgtc
     1021 atccaaccat ttcgtttcaa actttttaag gcttcaaata aatggcgaaa aaatctacta
     1081 atcatcgtat ccatactctc cttttgattc gtcacgaacg acacggccat tttcaatggc
     1141 aatgacacgg tggcgcaagg tatttacaat ctggctatta tgagtcgcca tcaaaatagt
     1201 tgtcccttgt aggttaatcc gttccaagag attcataatt tcccatgaat tatccggatc
     1261 cagatttcct gttggctcat cagctatcaa tactttggga ttatttacaa ttgcacgcgc
     1321 aatcgcaatt cgctgctgct ccccacctga gagttcattt gggaaagaac gaaccttatg
     1381 cttcaatcca accaagtcca aaacttccat cactcgtctt ttgatattac ggcgattttc
     1441 cccgattact tccatagcgt aagcaatatt ttcatagaca gttttctttg gtaacaattt
     1501 ataatcttgg aagacaaccc caacactacg acgtagaagc gggacatctt tctttttgat
     1561 cttaaccaga ttaaaaccag caactgatag acttccttta tcgattttta cttcacgata
     1621 cagagaacga ataaaagttg acttccctgc tcctgaaggt cctacgatgt aagcaaattc
     1681 ccccggttga acgctgaccg aaacaccgcg tagagcagtc gttccgttgt cgtatttttt
     1741 aacgacatct ctcatttcaa taattgacat gtgagttcct ttctatctta gctaattcgc
     1801 cacttgagat aagcatctat aaaaccatct aggtccccat ccataacctt atctacctga
     1861 gcaacctcaa agctagttcg gtgatctttt accatagtat aaggcgtgaa gacataagaa
     1921 cggatttggc ttccccaagt gatctccttt ttctcacctt tgagagaatc tacctccgca
     1981 gccttcttat cttgctccat ttgatagagc ttagcctgca acatcttcat ggcacgatct
     2041 ctatttccat actgggtacg atccactgtt gattggacaa caattccagt tggaatgtgg
     2101 gttaaacgta cacctgttga aaccttattg acgttttgtc caccggcacc acctgaacgg
     2161 aaggtatcca tcttgatatc atcttcacgg atttccactt caatagtatc atccaattct
     2221 ggcatcactt ctacagatgt gaaagaggta tggcgacgtt tggcagagtc aaatggtgag
     2281 attcgcacta agcggtgaac acccatttct gacttgagga gaccataggc attaggccct
     2341 tcaaatgata aagttaccga cttaatacca gcctcatcac ctgcttggta atccaacact
     2401 tccactttaa agcctttagc attaccataa cgagtataca tacgaagcaa catatcaccc
     2461 cagtcctgcg cctcagtacc accagaacct ggatggattt ccaagatggc attgttgtgg
     2521 tcataaggtt ctgacaagag tagagtcatc tcgtagctgg tcattatctt atcaagttcg
     2581 gctaactgcg ctaccagttc atcatgcact gactcgtctt cagccaaaaa atccaataaa
     2641 atttcgactt catcctgcaa ctcttccatc ttatggaagg tattgtaagt gttttttaat
     2701 tcattcaatt cttgcgacgt tttttgggcc gcaatattat cgttccaaaa atcaggttct
     2761 gtcatcttgt tttccaagat ggcaatctct tcctctagcc cttcgaggtc aaagagaccc
     2821 cctgaaagaa gctaattttt cacgatttgc gtcaattttc tgacgaatta ctgaaatgtc
     2881 cataaatact ccttttttac attatttcat tatagcatat tttatcattt ctttccatct
     2941 tttgctctaa tccccttttc atgaaaaaag aagcctttgg acttcccttc ttacaagact
     3001 tttgctgaag tgcgagcgat ttcttccact tgaataccat ttgcttcaaa tttttctctc
     3061 aaggctggta aatcaattga ttcatcgatt tgcacttcga taatcacctt accatcctta
     3121 cgcggaatat tgactgtatg ggagatattc aaattttctt ctacaatcaa agaaacaatt
     3181 tttccaagaa caccaacttc atcttctgta acaaagcgta cacgaatccc ttcttcgcca
     3241 taacctgcaa tttcaagaaa ggcttggaaa acgtcacggt cagtaataac tccgtatact
     3301 tgatggttat ctacgacagg gagaatacca atcttatttt tcaacatcag ataagttgca
     3361 tcttctagac tagcatagcc tgagacagtg acaacatcgc gaatcatgac atcttttact
     3421 tttgtcttat tcagaagata attcatctca tagatagaaa gacttgttgc tttagatgga
     3481 cttgcttgtg caatggttcc ctcagtcacc aaaccaacca attgatcatt ttcgataaca
     3541 ggcagacggt gcaaaccttg ctctctcatc aaatctgctg catgagatac tgttgtatct
     3601 ggactaatat aaactacctt gcgggtcata aaatctttaa ctgccatgag acttctcctt
     3661 ttctattctt atccctatta tacaatcttt ttgcaaatct atcaaacgct tacatttctt
     3721 tttcaaaatt tagaaaagta tgaataagct agcaaaaaga gctctaaaat cgagctctgt
     3781 gaatgaaggt aagaaacttt tcattcgatt ttttcaatta ttagaaatta agctttcaat
     3841 gtagatgcag atttgtttgc aatctcaatc taccggctaa aacaatcctc tggatttgat
     3901 gattgcttcg caatcttcat ccaccgacta aaaagggccc ccggactata ttgatgatta
     3961 cttcgtaatc tttatctgcc ggctaaaaca atcctctgga tttgatgatt gcttcgcaat
     4021 ctcaatctac cgactaaaaa gggcccccgg actatattga tgattacttc gtaatcttca
     4081 tctgccgact aaaacaatcc actggattgt tttagccacc tagatatgct tttctgactt
     4141 cttctgatga agcgagttct tttcctgttc ctgataggac gatttttcct gtttccaata
     4201 catatcctcg gtcagagatt gcaagtgctt tattggcatt ttgttcaatc aagaggacgg
     4261 ttgttccttg cttctgaata tcttgaatga tatcaaaaat ctcttggatg aagattgggg
     4321 caagtcccat tgatggttca tctaaaagaa gaagttttgg tgttgacata agagcgcgtc
     4381 ccatggcaag catttgttgt tcccctcctg aaagagtagc tgcatcttgg ttcttacgtt
     4441 cttcaagacg aggaaagcgt gagaaaacct tcttcaagtt agcttgattt tcttcacgat
     4501 ttttctttaa gaaagctccc atttcaagat tttccataac agtcaagcca ggaaagacgt
     4561 ggcgtccttc tggaacttgt gaaagaccac ctgccacgat tttctgagct ggtatttttt
     4621 ggatttcttg acctaaaaat tcaatctttc ctgaacttgg tcgaaccaaa cctgacaagg
     4681 tgcgaagaat agttgtctta cctgcaccgt tggcaccgat aagggaaaca acttctcctt
     4741 cattaacttc aaagcttaca tcacggactg cttggatcat accgtaatgc acagaaagat
     4801 tttcaacttt taacatagac attaggcttc acctcctaga taagcttcga taacgcgttt
     4861 attggtctta atttcgtctg gagttccttg agcaattaaa cggccatatt caagtacgta
     4921 gatacgttct gttacttcca tgaccagatt catatcgtgt tcaatcaaca tgattgtaat
     4981 cttaaattca tctttgatac gacgaattaa ctcagtcaat tcggctgttt cctgtgggtt
     5041 catacctgct gctggttcat ctaagaagag aattttaggt tccgtagcaa gggcacgaac
     5101 aatttccaaa cgacgttgtt gtccgtagga aagattttta gcaagagtct ctgcatcacc
     5161 atctaaatca aagattttca acaattccaa agctttagcc tttaattctt tttcactctt
     5221 gtaaaaagct ggtaagcgta agaaactagt aaaaacatgc tgtttgtgat ggtttccaaa
     5281 agcaatcaaa acattatcta aaactgttaa atctttaaag agacggatat tttggaaagt
     5341 acgtccaagt cccaaagagg caatcttata aggtgatttc ccattcaaaa ggtgaccatc
     5401 tagggttact gttccctcgc ttggttcata aacaccggtc aaaaggttga aaagggtggt
     5461 tttcccagct ccgtttggac cgattaatcc aaccagttcc ccttcgttca attcaagagt
     5521 cacatctcca acagctgtta gaccaccaaa atgtttggtt aactgtttta cttcaagtaa
     5581 tgccattagt tttgttcctc cttcttagat tttttaaaga aacgtgatag gctcagttcc
     5641 cacgttccaa ggagtccacc tggtctgaaa atcattacca ataccaaggc taaagcgtaa
     5701 ataatcatac gcacactagc aacatcttgg agaagcatat tcaaaattcc cagaacaata
     5761 gccgaaacaa tcgcacctgt aatggaaccg agtccaccaa atacaacaat aatcaaaacg
     5821 ttgattgagt taatgaaggt gtaatctttc ggtacaacag acccgataaa tcctgcctga
     5881 agtgacccag caatacttgc agtaatggca ccaaagacaa aagcgatgat tttaatttta
     5941 gtcgtattaa ccccaactga ctcagcagcg atttcatctt cacgaacaga gagggttgaa
     6001 cggccaattg ggctacgcaa gaagttcaag gttgcaatgg ttgtaatcac gacaaagaag
     6061 taaaccattt gccaagttgt aaagttagga atccctaaga tacctgccgc accatttgta
     6121 agacttccac cattgatgat aaagatacgg ataatttcag aaacacctag agttgctacc
     6181 gcaagatagt cccccttcaa gcgcaaggtt ggaatgccga caagtaaggc aactgctcct
     6241 gaaagcaaag cccctacaag catagctcca aagaaggcac cgtaggttgg taatttagaa
     6301 ccaataatag ctgctgcata ggcaccaatc gccatgaaac cagcatgacc aagtgaaaat
     6361 tgtcctgaaa aaccaacgat taagttgaga ccaacagcca aaataatatt aattccaatt
     6421 tgttgtaaaa tctgtacata gaatagatta agtactccga ctgaaaccag tacactaatc
     6481 aagctatagc cagctaacaa aaggagtaac catagaatat taacttttaa attttccttc
     6541 atcgtttaca ccttctcttt cacattctta ccaaggatac cagctgggcg gacaatcaag
     6601 atcaacaaca agattccata aacaatggca tcacggaaat ctgacatccc aaaggcagtc
     6661 gcaaaggttt ccaatagacc aatcacaaag ccaccaagag ccgcaccagg aataattccg
     6721 ataccaccaa gtactgcggc aacgaaagat ttaagacctg gagtaacccc catcaaaggc
     6781 tcaagagagt tataataaag agcaatcaga acaccagccg cacccgcaag agcagaaccc
     6841 aaagcgaagg taaagctaat cgtacggttt acattgatcc ccatcaattg cgccgcgtcg
     6901 ctatctactg atactgcacg catggctttc cccatcttag tcttttggac aatgacttgt
     6961 aacaaaatca tcaaaatcaa ggaaatggcc aaaatcatta actgcacatt tgttaagcta
     7021 attggtccca aatcatatcg aactgtttga atcgcttgag ggaaggcacg ggtattggca
     7081 ccaaccagat agaccattcc atactccaat aggaaagaaa ccccaatagc cgtaatcaaa
     7141 acagcaatac gagtagagtg gcgcaaaggt cggtaagcaa gaaactcaat cacgacacca
     7201 agaatagctg tcgctagcat agctacaata agcgctacaa agaaattcat ttggaaagaa
     7261 ttgatcaaga aataaccgat aaaggctccc atcatataaa tatcaccatg ggcgaagttg
     7321 atgagcttga taattccgta aaccatggta tatcctaggg ctaacagcgc gtaaacacta
     7381 cctagaatca aaccatttac gagttgttgg agcataagat tcactctttc tatttataat
     7441 tccgagggtt ttccctcact ttttgatagg ttcttatact caatgaaaat caaagagcaa
     7501 actaggaaac tagccgcagg ttgctcaaag cactgctttg aggttgtaga taagactgac
     7561 gaagtcagtc acatatataa tccaaggcga cgttgacgca gtttgaagag attttcgaag
     7621 agtattaaat atcgaaacag ggagtgagtc aaaggctcat tccctatttc aacatttttc
     7681 tattatggtt ttacaacttc tgctgcttca actttaccat tgttcatggt catcatgtaa
     7741 gcagttttga ctgtgttgtg gtctgcatcg aagcttgttt gaccagttac accttcaaaa
     7801 tcttttgttt tagcaaggtt atccttgatt tcacctgaat ttttagcacc ttttgctgcg
     7861 tttgctacaa ggtgaactga atcataagcc aaggctgcaa atgttgaagg ctcttcattg
     7921 tacttagcac ggtaagcgtc aaggaaggct ttagctttag ctgaaacttc tacagtagtt
     7981 gagaagcctg agataaagta gatgtttgat gctttttcag cagttgcttg ttgtacaaac
     8041 tcctcaccgt tgaatccatc accaccaacg attggtttgt caattcccat gccacgcgct
     8101 tggtttacaa tcttaccagc ctcattatag taaccaggaa caacgatagc atcaaagtct
     8161 ttccctttca tgtttgtaag ggctgcttgg aagtctgtgt cacctgctac gaaagtttca
     8221 tctgcaacga tttcaccctt gtatgactcg cggaaagatt tagcaatccc tttagcatag
     8281 tcactggcat tgtcagtgta aagaacaact ttcttagcat ttaatttttc agaaacatag
     8341 tttgagataa tttttccttg gaagctatct tggaaagttc caataaagag gtaatcttga
     8401 cctttagtca atccatcttg agtcgcactt ggtgagatca atggaacacc tgcttttgta
     8461 gcgttcgcta ccgcagctgc agtcgcacca gatgtcgcag gtcctacgac tgctgatact
     8521 ttagattggg ttacaaggtt agttgtaact gaagcagcct cagctgtttc agacttatta
     8581 tctttatcga ctacttcgat ttgttttcca tcgataccac ctgcggcatt gatttcatca
     8641 acagccaatt gggcaccttt ttgttcagct gttccgtatg cagctaaaga acctgattct
     8701 tcaaagttaa acccgatttt aattgtcttt tcctctactg agttaccagc agtgttgact
     8761 gctccagact tcacttctac acaggctgca agaagtgcta cacttgcaag cgccacaaac
     8821 gatagggcaa attttttctt catctttttg tctccttatt tcttaaatag tctgttaaga
     8881 atataccgaa ttatcagaaa attgtcaatg ttttccttga actttttcga tgataacgtt
     8941 ttcctatcga taaagattgc ccacaaaggg tgtttccaac tcttggatat gacaaaccct
     9001 aactttttta ataaattttt ccttgctcaa gcgtccgacc aattgctcca cttcttgagt
     9061 tggaacatag agttgtaagt aacgatgttt cttggaatga taggtaatat ctccataatc
     9121 ctgcagtttt ttggcatcac gattatagta aagatagata atcaagccag agcgattgac
     9181 tttttcaaac atgataaatc ctctttctaa gaaatctctc cctattatac caaaaaaagc
     9241 aaacccagtc gagtttgcct tctatcatca ttagttcaat gaattgttgg ccataatttc
     9301 atcaataaag ccatattcaa gtgtttcctg ggcgctcatc cagttatcac gttctgcatc
     9361 tgcatggact ttttccattg actgacctga attttcagcc aagatttttt ccaaggtatt
     9421 acgagttttg agcaagtgtt ctgcagcgat agccatatca gtttgttggg taccaccacc
     9481 tgtaccgccc attggttggt gaatcatgta ttcagcattt ggaagcatga aacgtttgcc
     9541 ttttgctcca cttgatgcga tgactgttcc catagatgca gccattccca taacaatggt
     9601 ttggacatct gccttgataa agttcatggt atctacgatt gccaaaccag ctgaaacaga
     9661 accacctggt gtattgacat aaaggtaaat atcttttgta ctatcttggg catccaagaa
     9721 aagcagttgg gcaataacag agttagccat attgtcttca accggacctg tcagcataat
     9781 gatgcggtct ttgagaagac gtgagtaaat atcgtaagaa cgttctccac ggcttgtttg
     9841 ttcaataact acaggaatca ttcatttctc cttttgagtt ttaattttgt tggtcaaatg
     9901 actgaagata agactattat aatatcttgg tcaaaaaagg tcaaattttt gctctgcttt
     9961 cattagacag aaacaaaaac ccaacctcct ttcgtgactg gaaatacttt tccaagtcat
    10021 tcttcttttc gatcttattt tgtaccgaac aagcggtctc cagcatctcc aagacctgga
    10081 acgatataac cgtgttcgtt caaacgttca tccaaggctg ctgtaaagat ttctacatct
    10141 ggatgagctt cttgaagggc ttttacaccc tctggagcag atacaaggca gacaaatttg
    10201 atatttgatg cgccacgttt tttaagagaa tcaacagcca agattgctga gccacctgtt
    10261 gccaacattg ggtctactac aaaaatttga cgttggtcaa tgtcctcagg caatttcacc
    10321 aagtattcaa ctggttgaaa tgtttcttca tcacggtaca taccgatgtg gccaacttta
    10381 gcagctggaa ccaagctcaa gagaccatca accatcccga tacctgcacg caagattggg
    10441 acgatggcca atttcttacc tgccaattgt ttttgaactg tttttgtaat tggtgtttcg
    10501 atttccacat cttctagtgg aagatcacga agtacttcat accccatcaa cattgcaatc
    10561 tcatctacta gctcacgaaa agcttttgta gaagtatctg tacgacgcaa gattgacaat
    10621 ttgtgttgaa tcagtgggtg attaataact tcaatttttc ccatttttgg aattccttct
    10681 ttcaatttat tcttcttatt ataccaaaaa acgggttaaa aatctttcta aaccatttat
    10741 ttttgataat ttttacatta gatcagcctc tttaagagct gtctgtactg tctcaagtgg
    10801 taaatgggtc aattctgtcc ctttttcttg ataaaggtat tgggcgtagt cgtccattcg
    10861 gtactggttg atataaacca cacgcttgca gccgacctga agcaattgtt ttgtacagtt
    10921 gagacaagga aaatgggtta cataggctgt aaagcctttg ggaacaccac gctcagcacc
    10981 ttgaaggata gcattgacct cagcgtgaag ggtgcgaaca cagtggcctt caatgaccaa
    11041 acattcgtga tcaatacaat gctcagtccc tgacaccgaa ccattgtaac cagtggaaat
    11101 aaccttatta tcttttacca gaatcgcgcc cactttagca cgtttacaag tggaacgatt
    11161 cgcaattagt agagcttggg ctgcaaaata ctcatcccag gccagtcttt tttcagtcat
    11221 ctcttttctc ctttttctct attttttaaa aaatggtaaa cctaaatctg caatcttttc
    11281 agctggtacc ttcatgccat ccttgatcca ttttagaagg acagagacga tggctgagct
    11341 ccagaaggaa tgaagataag agctgacacc ttttgatttc ccatggtatt tttctagaaa
    11401 ttcctgcatg gcttggacaa agattttttc cagatggtaa tccaaggcca attgaattac
    11461 tctagcttcc tttctggcct cccggaaaag gtgaacccaa accaaataaa ggtctgtctt
    11521 taaatcgtaa tgatgcagct gttccataat attgtggaca gttcgtttaa agacgctctc
    11581 taaaatttcc tctttggagt cataattgcg ataaaaggcc gcacgcgaaa cacctgcacg
    11641 tttgaccaat tcagaaatac taatcttggt cagttccttt ttttccaaga gttgcaagag
    11701 ggctgtttca atggcttctc tggttaataa attggattct tggtttgatt ttctgagatt
    11761 ttcaagagac ttttcagaga ttctacgttc agacataaca ttttctttct acttgtcaca
    11821 acagacggat gatgcttttg tttcaagggt tttcatgata taattgtaaa aaaagacaga
    11881 acctttgtca atgtataact gacaaagatg gagaatttct atgacttgga agattattgc
    11941 tgactctggt tgtgattatc gtcaactgcc aacaccagct attaacacaa cctttgtaag
    12001 tgtcccctta accattcaag tagctgatca ggtctttgtt gatgacgcca gtctcgatat
    12061 tgaccaaatg atggaaacca tgtatgcaac tgcagaagct tcaaaatcgg cttgtccaag
    12121 cccagatgac tatttgcgag catttgaagg tgccaaaaac attttcctag taaccatcac
    12181 aggtaccctt tctggcagtc acaatagtgc tcaactagca aagaatattt atctggaaga
    12241 ccatcctgac actaagattc atgtgattga tagtttatct gctggtggtg aagttgacct
    12301 actcgtagaa aaattgaatg acttgattga ccagggcttg tcttttgaag aagtggttga
    12361 agctatcacc gcctatcaag aaaaaactaa gttgctcttt gtcctagcca aagtcgataa
    12421 cttggtgaag aacggccgtt tgagcaagct tatcggtacg gtcgttggcc ttctcaacat
    12481 tcgtatggtc ggaaaagcta gtgaaactgg aactctcgaa ttgctacaaa aagcaagggg
    12541 atcaaagaaa tcagttcaag ctgcctatga tgagttagta aaagctggat atgctggtgg
    12601 ccgtattgtc atggcccaac gcaataacga aaaatgttgt caacagctct cagagcgaat
    12661 ccgtgaaacc ttcccacaag cggatattaa aattctacca acctctggtc tctgcagttt
    12721 ctatgcagaa gatggcggtt tgctgatggg ctatgaaatt gattaattgt attcttgaca
    12781 agaggtgacc atcatctctt gtttttttgt ggtacaatag agctatgaaa cattttgata
    12841 ctattgtcat cggtggggga cctgctggta tgatggctac gatttccagt agcttttatg
    12901 gacagaaaac cctcctcatc gaaaaaaatc ggaaacttgg aaaaaaatta gctgggactg
    12961 gtgggggacg ttgcaatgtg accaacaatg gtagcttaga caacctgcta gctggaattc
    13021 ctggaaacgg acgctttctt tacagtgttt tctcccagtt cgataatcat gacatcatca
    13081 acttttttac agaaaatggt gttaaactta aggtcgaaga ccacggacgc gtctttccag
    13141 ccagtgacaa gtctcggact attatcgaag ctttggaaaa gaaaatcacc gaactaggtg
    13201 gtcaagttgc tactcaaata gaaatcgttt ctgttaaaaa agtagatgac cagtttgtcc
    13261 ttaagtcagc ggatcaaacc ttcacttgtg agaaactcat tgtcacaaca ggtggtaagt
    13321 cttatccttc gactggttcg actggttttg gtcacgagat tgctcgccat tttaagcata
    13381 ccatcaccga tcttgaggct gctgaaagtc ctttattaac agattttcca cataaagcct
    13441 tacaagggat ttctttggac gatgtgaccc taagttatgg taagcatgtc atcactcatg
    13501 atttactctt tacccacttt ggtttgtcag gtcctgctgc cctacgcatg tctagctttg
    13561 tcaaaggtgg ggaggttctc tcactcgatg ttttgcctca actttctgag aaggacttgg
    13621 ttacatttct agaagaaaat cgggaaaaat ccttgaaaaa cgctttaaaa accttgttac
    13681 cagaacgctt ggccgaattt tttgtacaag gatatcctga aaaagtcaaa caactgactg
    13741 aaaaggaacg agaacaactt gtccagtcca ttaaagaact taaaattcct gtaactggaa
    13801 aaatgtccct tgcaaagtcc tttgttacca agggtggagt cagtctcaag gaaatcaatc
    13861 ctaaaaccct tgaaagtaag ctggtacctg gcctccactt tgcaggcgaa gttatggata
    13921 tcaatgccca cacaggtggc tttaacatca cttctgccct ctgtaccggc tgggtggcgg
    13981 gatcaaatcc aatctaaata tacattacta aatggaacaa tcccccaaaa aaaagaaagg
    14041 aactactttg gaacatatta tcttgctaag gggagtcact cctaatggaa aaaatgctat
    14101 ccctaaaatg tcttatctag tagatatctt gacagaagct gattttcaac aagttcgaac
    14161 ttatattcaa agtggaaata ttattcttga aagtaactta gctctcgaag aaatacgaga
    14221 acaggttcat actcta
//
LOCUS       DAVBEO010000052        14210 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 009
            SAMEA1678075-rid20185393.denovo.052, whole genome shotgun sequence.
ACCESSION   DAVBEO010000052 DAVBEO010000000
VERSION     DAVBEO010000052.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678075
            Sequence Read Archive: ERR226392
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 14210)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14210)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980207.1
            Genome Coverage       :: 150x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:50:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 72 of 147
            Pseudo Genes (incomplete)         :: 72 of 147
            Pseudo Genes (internal stop)      :: 42 of 147
            Pseudo Genes (multiple problems)  :: 32 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14210
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678075-rid20185393.denovo.052"
                     /strain="KS 009"
                     /db_xref="taxon:1313"
     gene            <1..193
                     /locus_tag="VQ543_001724"
     CDS             <1..193
                     /locus_tag="VQ543_001724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET2612408.1"
                     /translation="LKPLTVEDKAYNHALSKERSKVENIFAKVKTFKMISTTYRNHRK
                     HFGLRMNLIAGIINHELGF"
     gene            complement(529..2220)
                     /locus_tag="VQ543_001725"
     CDS             complement(529..2220)
                     /locus_tag="VQ543_001725"
                     /EC_number="6.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine--tRNA ligase"
                     /protein_id="HET2612409.1"
                     /translation="MNTKELIASELASIIDSLDQEAILKLLETPKNSEMGDIAFPAFS
                     LAKVERKAPQMIAAELAEKMNSQAFEKVVATGPYVNFFLDKSAISAQVLQAVTTEKEH
                     YADQNIGKQENVVIDMSSPNIAKPFSIGHLRSTVIGDSLSHIFQKIGYQTVKVNHLGD
                     WGKQFGMLIVAYKKWGDEEAVKAHPIDELLKLYVRINAEAENDPSLDEEAREWFRKLE
                     NGDEEALALWQWFRDESLVEFNRLYNELKVEFDSYNGEAFYNDKMDAVVDILSEKGLL
                     LESEGAQVVNLEKYGIEHPALIKKSDGATLYITRDLAAALYRKNEYQFAKSIYVVGQE
                     QSAHFKQLKAVLQEMGYDWSDDITHVPFGLVTKEGKKLSTRKGNVILLEPTVAEAVSR
                     AKVQIEAKNPELENKDQVAHAVGVGAIKFYDLKTDRTNGYDFDLEAMVSFEGETGPYV
                     QYAYARIQSILRKADFKPETAGNYSLNDTESWEIIKLIQDFPRIINRAADNFEPSIIA
                     KFAISLAQSFNKYYAHTRILDESPERDSRLALSYATAVVLKEALRLLGVEAPEKM"
     gene            2356..2802
                     /gene="argR"
                     /locus_tag="VQ543_001726"
     CDS             2356..2802
                     /gene="argR"
                     /locus_tag="VQ543_001726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HET2612410.1"
                     /translation="MRKRDRHQLIKKMITEEKLSTQKEIQDRLEAHNVCVTQTTLSRD
                     LREIGLTKVKKNDMVYYVLVNETEKIDLVEFLSHHLEGVARAEFTLVLHTKLGEASVL
                     ANIVDVNKDEWILGTVAGANTLLVICRDQHVAKLMEDRLLDLMKDK"
     gene            2853..5387
                     /gene="mutS"
                     /locus_tag="VQ543_001727"
     CDS             2853..5387
                     /gene="mutS"
                     /locus_tag="VQ543_001727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HET2612411.1"
                     /translation="MAIEKLSPGMQQYVDIKKQYPDAFLLFRMGDFYELFYEDAVNAA
                     QILEISLTSRNKNADNPIPMAGVPYHSAQQYIDVLIEQGYKVAIAEQMEDPKQAVGVV
                     KREVVQVITPGTVVDSSKLDSQNNFLVAIDREGNQFGLAYMDLVTGDFYVTGLLDFTL
                     VCGEIRNLKAREVVLGYDLSEEEEQILSCQMNLVLSYEKESFEDLHLLDLRLATVEQT
                     ASSKLLQYVHRTQMRELNHLKPVIRYEIKDFLQMDYATKASLDLVENARSGKKQGSLF
                     WLLDETKTAMGMRLLRSWIHRPLIDKERIVQRQEVVQVFLDHFFERSDLTDSLKGVYD
                     IERLASRVSFGKTNPKDLLQLATTLSSVPRIRAILEGMEQPALAYLIAQLDAIPELES
                     LISAAIAPEAPHVITDGGIIRTGFDETLDKYRCVLREGTSWIAEIEAKERENSGISTL
                     KIDYNKKDGYYFHVTNSQLGNVPAHFFRKATLKNSERFGTEELARIEGDMLEAREKSA
                     NLEYEIFMRIREEVGKYIQRLQALAQGIATVDVLQSLAVVAETQHLIRPEFGDDSQID
                     IRKGRHAVVEKVMGAQTYIPNTIQMAEDTSIQLITGPNMSGKSTYMRQLAMTAVMAQL
                     GSYVPAESAHLPIFDAIFTRIGAADDLVSGQSTFMVEMMEANNAISHATKNSLILFDE
                     LGRGTATYDGMALAQSIIEYIHEHIGAKTLFATHYHELTSLESSLQHLVNVHVATLEQ
                     DGQVTFLHKIEPGPADKSYGIHVAKIAGLPADLLARADKILTQLENQGTENPPPMRQT
                     SAVTEQISLFDRAEEHPILAELAKLDVYNMTPMQVMNVLVELKQKL"
     gene            5534..7228
                     /gene="patA"
                     /locus_tag="VQ543_001728"
     CDS             5534..7228
                     /gene="patA"
                     /locus_tag="VQ543_001728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000908145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit PatA"
                     /protein_id="HET2612412.1"
                     /translation="MLIQKIKTYKWQALASLLMTGLMVASSLLQPRYLQEVLGALLTG
                     KYEAIYSIGAWLIGVAVVGLVAGGLNVVLAAYIAQGVSSDLREDAFRKIQTFSYADIE
                     QFNAGNLVVRMTNDINQIQNVVMMTFQILFRLPLLFIGSFILAVQTLPSLWWVIVLMV
                     VLIFGLTAVMMGMMGPRFAKFQTLLERINAIAKENLRGVRVVKSFVQEKEQFAKFTEV
                     SDELLGQNLYIGYAFSVVEPFMMLVGYGAVFLSIWLVAGMVQSDPSVVGSIASFVNYL
                     SQIIFTIVMVGFLGNSVSRAMISMRRIREILDAEPAMTFKDVPDEELVGSLSFENVTF
                     TYPMDKEPMLKDVSFTIEPGQMVGVVGATGAGKSTLAQLIPRLFDPQEGAIKIGGKDI
                     REVSEGTLRKTVSIVLQRAILFSGTIADNLRQGKGNATLFEMERAANIAQASEFIHRM
                     EKTFESPVEERGTNFSGGQKQRMSIARGIVSNPRILIFDDSTSALDAKSERLVQEALN
                     KDLKGTTTIIIAQKISSVVHADKILVLNQGRLIGQGTHADLVANNAVYREIYETQK"
     gene            complement(7558..7827)
                     /locus_tag="VQ543_001729"
                     /pseudo
     CDS             complement(7558..7827)
                     /locus_tag="VQ543_001729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019770457.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
     gene            8019..9785
                     /gene="patB"
                     /locus_tag="VQ543_001730"
     CDS             8019..9785
                     /gene="patB"
                     /locus_tag="VQ543_001730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000859866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit PatB"
                     /protein_id="HET2612413.1"
                     /translation="MKTVQFFWHYFKVYKFSFVVVILMIVLATFAQALFPVFSGQAVT
                     QLANLVQAYQNGNPELVWQSLSGIMVNLGLLVLVLFISSVIYMCLMTHVIAESTNEMR
                     KGLFGKLAQLTVSFFDRRQDGDILSHFTSDLDNILQAFNESLIQVMSNIVLYIGLILV
                     MFSRNVTLALITIASTPLAFLMLIFIVKMARKYTNLQQKEVGKLNAYMDESISGQKAV
                     IVQGIQEDMMAGFLEQNERVRKATFKGRMFSGILFPVMNGMSLINTAIVIFAGSAVLL
                     NDKSIETSTALGLIVMFAQFSQQYYQPIIQVAASWGSLQLAFTGAERIQEMFDAEEEI
                     RPEKAPTFTKLQESVEISHIDFSYLPDKPILKDVSISAPKGQMTAVVGPTGSGKTTIM
                     NLINRFYDVDAGGIYFDGKDIRGYDLDSLRSKVGIVLQDSVLFSGTIRDNIRFGVPDA
                     SQEMVEVAAKATHIHDYIESLPDKYDTLIDDDQSIFSTGQKQLISIARTLMTDPEVLI
                     LDEATSNVDTVTESKIQHAMEVVVAGRTSFVIAHRLKTILNADQIIVLKDGEVIERGN
                     HHELLKLGGFYSELYHNQFVFE"
     gene            9924..10613
                     /locus_tag="VQ543_001731"
     CDS             9924..10613
                     /locus_tag="VQ543_001731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HET2612414.1"
                     /translation="MARTVVGVAANLCPVDAEGKIIHSSVSCRFAEIIRQVGGLPLVI
                     PVGDESVVRDYVEMIDKLILTGGQNVHPQFYGEKKTVESDDYNLVRDEFELALLKEAL
                     RQNKPIMAICRGVQLVNVAFGGTLNQEIEGHWQGLPFGTSHSIETVEGSVVAKLFGKE
                     SQVNSVHRQSIKDLAPNFRVTAIDSRDQTIEAIESIDEHRIIGLQWHPEFLVNEEDGN
                     LELFEYLLDEL"
     gene            10617..10796
                     /locus_tag="VQ543_001732"
     CDS             10617..10796
                     /locus_tag="VQ543_001732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2612415.1"
                     /translation="MEHLVVLSFIFSKFLECGILRKRLNSDKNWRNSTKKLEKNEGKR
                     YDRKEEILEEEHVTY"
     gene            10783..12132
                     /locus_tag="VQ543_001733"
     CDS             10783..12132
                     /locus_tag="VQ543_001733"
                     /EC_number="5.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="HET2612416.1"
                     /translation="MSHIKFDYSKVLDKFVAPHEVEYMQSQVTAADELIRKGTGAGSD
                     FLGWLDLPEKYDREEFDRILKAAEQIKSDSDVLVVIGIGGSYLGAKAAIDFLNHHFAN
                     LQTKEERKAPQILYAGNSISSTYLADLVEYVADKDFSVNVISKSGTTTEPAIAFRVFK
                     ELLVKKYGQEEANKRIYATTDRQKGAVKVEADANGWGTFVVPDDIGGRFSVLTAVGLL
                     PIAASGADIKALMEGANAARKDYTSDKISENEAYQYAAVRNILYRKGYATEILVNYEP
                     SLQYFSEWWKQLAGESEGKDQKGIYPTSANFSTDLHSLGQFIQEGTRIMFETVVRVDK
                     PRKNVLIPTLEEDLDGLGYLQGKDVDFVNKKATDGVLLAHTDGDVPNMYVTLPEQDAF
                     TLGYTIYFFELAIALSGYLNAINPFDQPGVEAYKRNMFALLGKPGFEELSKELNARL"
     gene            12256..13716
                     /locus_tag="VQ543_001734"
     CDS             12256..13716
                     /locus_tag="VQ543_001734"
                     /EC_number="6.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--tRNA ligase"
                     /protein_id="HET2612417.1"
                     /translation="MSKDIRVRYAPSPTGLLHIGNARTALFNYLYARHHGGTFLIRIE
                     DTDRKRHVEDGERSQLENLRWLGMDWDESPESHENYRQSERLDLYQKYIDQLLAEGKA
                     YKSYVTEEELAAERERQEVAGETPRYINEYLGMSEEEKAAYIAEREAAGIIPTVRLAV
                     NESGIYKWHDMVKGDIEFEGGNIGGDWVIQKKDGYPTYNFAVVIDDHDMQISHVIRGD
                     DHIANTPKQLMVYEALGWEAPEFGHMTLIINSETGKKLSKRDTNTLQFIEDYRKKGYL
                     PEAVFNFIALLGWNPGGEDEIFSREELIKLFDENRLSKSPAAFDQKKLDWMSNDYIKN
                     ADLETIFEMAKPFLEEAGRLTDKAEKLVELYKPQMKSVDEIIPLTDLFFSDFPELTEA
                     EREVMTGETVPTVLEAFKAKLEAMTDDKFVTENIFPQIKAVQKETGIKGKNLFMPIRI
                     AVSGEMHGPELPDTIFLLGREKSIQHIENMLKEISK"
     gene            13730..14164
                     /locus_tag="VQ543_001735"
     CDS             13730..14164
                     /locus_tag="VQ543_001735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HET2612418.1"
                     /translation="MDIWEKMYEEAQKLYNPHEVSDFVYANHVVAAVEAEDGQIFTGF
                     CMEGTCGVFHLCAERAALFNTYQFSGQTKVKKVLAFRDKPPYGGSSAMPCGACREFLL
                     ELNAENKDAEFMMDYNIRKTVKVAELIPYWWGEERASKFNER"
BASE COUNT         4167 a         2742 c         3202 g         4099 t
ORIGIN      
        1 actcaagcca ctaacagttg aagataaagc ctataaccat gcgctatcca aggagagaag
       61 caaggttgag aacatctttg ccaaagtaaa aacgtttaaa atgatttcaa caacctatcg
      121 aaatcatcgt aaacacttcg gattacgaat gaatttgatt gctggcatta tcaatcatga
      181 actaggattc tagttttgca ggaagtctat tatttggtta ggtgaattag tgaagcgttt
      241 aggcaagtgt ctctggttac gacgtcatgg actctaaatc gattatattt aggggtcatg
      301 actagtgaag cagttagcta gttcgcatat aagcggctag cgtctaacaa ttaggaactt
      361 tagttccaat aactttaaga ttacgacgtt ttaggacata aatcgatcat atttatgtcc
      421 taaaactagt gaagtatgtc ctaaaactag tgaagcgcct agccaaagtc cgaataggat
      481 ttggcgttag ttacttagat tgctttgcaa tcaagtaact ttggcgattt acatcttctc
      541 tggcgcttct actccaagca agcgaagggc ttctttgaga acgactgcgg ttgcgtagct
      601 gagggctaga cggctgtcgc gttctgggct ttcatccaag atacgtgtat gtgcatagta
      661 tttgttaaag gattgagcca ggctaattgc aaatttagca atgatagaag gttcaaagtt
      721 atctgccgca cggttgataa tacgtgggaa gtcttgaatg agtttaatga tttcccagct
      781 ttcagtatca ttcaagctat agttgccagc tgtttctggt ttgaaatcgg ctttgcgtaa
      841 gatagattgg atacgagcgt aggcatattg aacgtaaggt ccagtttcac cctcgaagga
      901 taccatagcc tctaggtcga agtcgtatcc atttgtacgg tcggttttga ggtcatagaa
      961 tttaatggct ccaaccccaa cagcatgtgc tacttggtct ttgttttcta gttcaggatt
     1021 tttagcctcg atttggacct tggcacggct aacagcctct gcaacagtag gctctagcaa
     1081 gatgacattc cctttacgag tagagagttt cttcccttct tttgtaacca aaccaaaagg
     1141 aacgtgagta atgtcgtcac tccagtcgta gcccatctct tgcaagacag ctttgagctg
     1201 tttaaagtgg gcagattgtt cttgaccaac gacatagata gatttagcaa attggtattc
     1261 gtttttacgg tagagggctg cagccaagtc acgtgtgata tagagagttg caccatcaga
     1321 cttcttgatg agggctggat gttcaattcc gtatttctca agattcacaa cttgggcacc
     1381 ttctgattca agaagtagtc ctttttcaga aagaatgtct acaactgcat ccatcttatc
     1441 attgtagaag gcttctccgt tatagctgtc aaattcaacc ttcaattcat tgtaaaggcg
     1501 gttaaattcc actaaacttt catcgcggaa ccattgccaa agagcgagag cttcctcatc
     1561 tccattttca agtttacgga accattcgcg cgcttcttca tccaagctag ggtcattttc
     1621 agcttcagcg ttgatgcgga catagagttt aaggagttca tcgattggat gagcttttac
     1681 agcttcttcg tcgccccatt ttttgtaggc aacaatcaac atcccaaatt gtttacccca
     1741 gtctcccaaa tggttgacct tgaccgtttg ataaccgatt ttttggaaaa tatgtgacaa
     1801 gctatctccg ataacagttg aacgcaggtg gccaatagaa aatggtttag cgatattcgg
     1861 actagacatg tcgataacaa cattttcttg tttaccaata ttttggtcag catagtgttc
     1921 tttttcagtg gtaacagctt gcaatacttg agcagaaatg gcagatttat caaggaaaaa
     1981 gttaacgtaa ggtcctgttg cgacaacttt ttcaaaggct tggctgttca ttttttcagc
     2041 cagttcagcc gcaatcattt gtggtgcttt acgttcgact ttggcaagag aaaaagcagg
     2101 gaaagcgatg tcacccattt ctgagttttt aggggtttcc agtaacttta aaatagcctc
     2161 ttggtccagg ctatcaatga tgctagccaa ttcgctagca atcaattctt ttgtattcat
     2221 taagagctcc tttttggact tttctactat tttatcacaa ttttaaagaa agaagaaaaa
     2281 atttttgaaa tctcctgttt ttttggtata atatggttat aaatatagtt ataaatatgc
     2341 acgcaagagg attttatgag aaaaagagat cgtcatcagt taataaaaaa aatgattact
     2401 gaggagaaat taagtacaca aaaagaaatt caagatcggt tggaggcgca caatgtttgt
     2461 gtgacgcaga caaccttgtc tcgtgatttg cgcgaaatcg gcttgaccaa ggtcaagaaa
     2521 aatgatatgg tgtattatgt actagtaaat gagacagaaa agattgattt ggtggaattt
     2581 ttgtctcatc atttagaagg tgttgcaaga gcagagttta ccttggtgct tcataccaaa
     2641 ttgggagaag cctctgtttt ggcaaatatt gtagatgtaa ataaggatga atggatttta
     2701 ggaacagttg ctggtgccaa taccttattg gttatttgtc gagatcagca cgttgccaaa
     2761 ctcatggaag atcgtttgct agatttgatg aaagataagt aaggtcttgg gagttgctct
     2821 caagacttat ttttgaaaag gagagacaga aaatggcgat agaaaagcta tcacccggca
     2881 tgcaacagta tgtggatatt aaaaagcaat atccagatgc ttttttgctc tttcggatgg
     2941 gtgattttta tgaattattt tatgaggatg cggtcaatgc tgcgcagatt ctggaaattt
     3001 ccttaacgag tcgcaacaag aatgccgaca atccgatccc tatggcgggt gttccctatc
     3061 attctgccca acagtatatc gatgtcttga ttgagcaggg ttataaggtg gctatcgcag
     3121 agcagatgga agatcctaaa caagcagttg gggttgttaa acgagaggtt gttcaggtca
     3181 ttacgccagg gacagtggtc gatagcagta agctggacag tcagaataat tttttggttg
     3241 ccatagaccg cgaaggcaat caatttggcc tagcttatat ggatttggtg acgggtgact
     3301 tttatgtgac aggtcttttg gatttcacgc tggtttgtgg ggaaatccgt aacctcaagg
     3361 ctcgagaagt ggtgttgggt tatgacttgt ctgaggaaga agaacaaatc ctcagctgcc
     3421 agatgaatct ggtactctct tatgaaaaag aaagctttga agaccttcat ttattggatt
     3481 tgcgattggc aacggtggag caaacggcat ctagtaagct gctccagtat gttcatcgga
     3541 ctcagatgag ggaattgaac cacctcaaac ctgttatccg ctacgaaatt aaggatttct
     3601 tgcagatgga ttatgcgacc aaggctagtc tggatttggt tgagaatgct cgctcaggta
     3661 agaaacaagg cagtcttttc tggcttttgg atgaaaccaa aacggctatg gggatgcgtc
     3721 tcttgcgttc ttggattcat cgccccttga ttgataagga acgaatcgtc caacgtcaag
     3781 aagtagtgca ggtctttctc gaccatttct ttgagcgtag tgacttgaca gacagtctca
     3841 agggtgttta tgacattgag cgcttggcta gtcgtgtttc ttttggcaaa accaatccaa
     3901 aggatctctt gcagttggcg actaccttgt ctagtgtgcc acggattcgt gcgattttag
     3961 aagggatgga gcaacctgct ctagcctatc tcatcgcaca actggatgca atccctgagt
     4021 tggagagttt gattagcgca gcgattgctc ctgaagctcc tcatgtgatt acagatgggg
     4081 gaattatccg gactggattt gatgagactt tagacaagta tcgttgcgtt ctcagagaag
     4141 ggactagctg gattgctgag attgaggcta aggagcgaga aaactctggt atcagcacgc
     4201 tcaagattga ctacaataaa aaggatggct actattttca tgtgaccaat tcgcaactgg
     4261 gaaatgtgcc agcccacttt ttccgcaagg cgacgctgaa aaactcagaa cgctttggaa
     4321 ccgaagaatt agcccgtatc gagggagata tgcttgaggc gcgtgagaag tcagccaacc
     4381 tcgaatacga aatatttatg cgcattcgtg aagaggtcgg caagtacatc cagcgtttac
     4441 aagctttagc ccaaggaatt gcgacggttg atgtcttaca gagtctggcg gttgtggctg
     4501 aaacccagca tttgattcga cctgagtttg gtgacgattc acaaattgat atccggaaag
     4561 ggcgccatgc tgtcgttgaa aaggttatgg gggctcagac ctatattcca aatacgattc
     4621 agatggcaga agataccagt attcaactga ttacagggcc aaacatgagt gggaagtcta
     4681 cctatatgcg tcagttagcc atgacggcgg ttatggccca gctgggttcc tatgttcctg
     4741 ctgaaagcgc ccatttaccg atttttgatg cgatttttac ccgtatcgga gcagcagatg
     4801 acttggtttc gggtcagtca acctttatgg tggagatgat ggaggccaat aatgccattt
     4861 cgcatgcgac caagaactct ctcattctct ttgatgaatt gggacgtgga actgcaactt
     4921 atgacgggat ggctcttgct cagtccatca tcgaatatat ccatgagcac atcggagcta
     4981 agaccctctt tgcgacccac taccatgagt tgactagtct ggagtctagt ttacaacact
     5041 tggtcaatgt ccacgtggca actttggagc aggatgggca ggtcaccttc cttcacaaga
     5101 ttgaaccggg accagctgat aaatcctacg gtatccatgt tgccaagatt gctggcttgc
     5161 cagcagacct tttagcaagg gcggataaga ttttgactca gctagagaat caaggaacag
     5221 agaatcctcc tcccatgaga caaactagtg ctgtcactga acagatttca ctctttgata
     5281 gggcagaaga gcatcctatc ctagcagaat tagctaaact ggatgtgtat aatatgacac
     5341 ctatgcaggt tatgaatgtc ttagtagagt taaaacagaa actataaaac caagactcac
     5401 tagttaatct agctgtagca aggagacttc tttgacaatt ctccactttt ttgctagaat
     5461 gacatcacac aaacagaatg aaaaggagct gacgcattgt cgctcccttt tgtctatttt
     5521 ttaaggagaa agtatgctga ttcagaaaat aaaaacctac aagtggcagg ccctggcttc
     5581 gctcctgatg acaggcttga tggttgctag ttcacttctg caaccgcgtt atctgcagga
     5641 agtcttaggc gccctcctta ctgggaaata tgaagctatt tatagtatcg gggcttggtt
     5701 gattggtgtg gccgtagtcg gtctagttgc tggtggactc aatgttgtcc tcgcagccta
     5761 tattgcccaa ggagtttcat ccgaccttcg ggaggatgcc ttccgtaaaa ttcaaacctt
     5821 ttcttatgct gatattgaac aatttaatgc gggaaatcta gtcgttcgaa tgacaaatga
     5881 tatcaaccag attcagaacg ttgtcatgat gaccttccag attcttttca gacttcccct
     5941 cttgttcatc ggttcgttta tcctagcggt tcaaacctta ccttctctgt ggtgggtgat
     6001 tgttctcatg gtagtcttga tttttggttt gactgctgtc atgatgggaa tgatggggcc
     6061 tcgttttgcc aagtttcaaa cccttcttga gcgcatcaat gccattgcca aggaaaattt
     6121 acgtggcgtt cgtgtggtca agtcctttgt ccaagaaaaa gagcaatttg ctaagtttac
     6181 agaggtctca gacgagcttc ttggtcaaaa cctttacatt ggttatgcct tttcagtagt
     6241 ggaacccttt atgatgttgg ttggttacgg ggcggtcttc ctctctattt ggctggtcgc
     6301 gggaatggtt cagtcggatc cgtctgttgt tggttccatc gcttcttttg ttaattacct
     6361 aagccagatt atctttacca ttgttatggt tggatttttg ggaaattctg tcagccgtgc
     6421 catgatttcc atgcgtcgta ttcgagaaat tcttgacgca gagccagcta tgaccttcaa
     6481 ggatgtccca gatgaagagt tggttggaag ccttagcttt gaaaatgtga cctttaccta
     6541 tccaatggac aaggaaccga tgctgaaaga tgtgagcttt actattgaac ctggtcaaat
     6601 ggttggtgta gttggagcga ctggtgcagg aaagtcaacc ttggctcaat tgattccacg
     6661 tctctttgat ccacaggaag gggctatcaa aatcggaggt aaggatattc gagaagtgag
     6721 tgaaggaacc ctgcgtaaaa cagtttccat cgttctccaa cgtgccattc tttttagtgg
     6781 aacgattgca gataacttga gacaggggaa gggaaatgct actctatttg aaatggagcg
     6841 cgcagccaat attgcccagg ctagtgaatt cattcatcgt atggagaaaa cctttgaaag
     6901 tccagttgaa gaacggggaa ccaatttctc tggtggacaa aaacaaagga tgtcgattgc
     6961 gcgtgggatt gtcagcaatc cacgtattct gatttttgat gattcgacct cagccttgga
     7021 tgccaaatca gagcgcttgg tgcaagaagc tttgaataag gacttgaagg ggacgacaac
     7081 cattattatt gctcaaaaaa ttagctcggt tgtccatgca gacaagatct tggttctaaa
     7141 tcaaggacga ttgattggtc aaggcacgca tgcagacttg gttgccaaca atgccgttta
     7201 ccgtgaaatc tatgaaacac agaaatgaaa gacaaactat aagaaaagtc aatagtttta
     7261 tctaaactat ttcttatttc aatttgatga tttggcgatg attttagagc acggcaaaaa
     7321 gcccttgaaa aagtccattt tttcaaaggt aatcctgtgt tgatttcaga aattacatca
     7381 ctttttgttc gtcaaatggc agctcttttt taggatataa aacagggttc ggataagttt
     7441 ttttgcaagg tggatgatgg ctacattgta atgttttcct tgttataact tagtcttaag
     7501 ataggcctta aaagcaggtg aaaagtgagg gcatgctttg gcagcttgta tgagtaccta
     7561 ccgcagatga ggggaacccc gtttgaccat tcttccagct aaatcaatct gacctgactg
     7621 ataaatagaa gaatccagtc cagcgaaagc ttgtaattga gcaggattat caaaggcatg
     7681 aatatttcga atctcggcta aaatgaccgc ccctaaacga ttcccaatcc cagtaaccgt
     7741 cgtgatgacc gagttgaact cagccatcaa gtcattgaca catttttccg ccttgtcaat
     7801 gagcctcttg taatgtttga tgatttcatt acacgagata aaacgtctat gcgttatcaa
     7861 actcattacc aattaaaaca aaaagctgtg gttagatcct ttcggaaatc gtcaagcgat
     7921 tggaggaaat gaactaatcc acagcggctt attccaagta taccacttgg gctttggcag
     7981 tagctaactg cgctaaatat aatataagga ggagtaaaat gaagacagtt caattttttt
     8041 ggcattattt taaggtctac aagttctcat ttgtagttgt catcctgatg attgttctgg
     8101 cgacttttgc ccaagccctc tttccagtct tttctggaca agcggtgacg cagctagcca
     8161 atttagttca agcttatcaa aatggcaatc cagaacttgt atggcaaagc ctatcaggaa
     8221 tcatggtcaa tcttggcctg ctggttttgg ttctatttat ctctagtgta atatacatgt
     8281 gtctcatgac gcacgtgatt gcagaatcga ccaacgagat gcgcaaaggc ctctttggta
     8341 agcttgctca gttgacggtt tctttctttg accgtcgaca agatggcgat atcttgtctc
     8401 attttaccag tgatttggat aatatcctcc aagcctttaa cgaaagcttg attcaggtca
     8461 tgagcaatat tgttttatac attggtctga ttcttgtcat gttttcgaga aatgtgacgc
     8521 tggctctcat caccattgcc agcaccccat tggctttcct tatgctgatt ttcatcgtga
     8581 aaatggcacg caaatacacc aacctccagc agaaagaggt agggaagctc aacgcctata
     8641 tggatgagag catctcaggc caaaaagccg tgattgtgca aggaattcaa gaggatatga
     8701 tggcaggatt tcttgaacaa aatgagcgcg tgcgcaaggc aacctttaaa ggaagaatgt
     8761 tctcaggaat tcttttccct gtcatgaatg ggatgagcct gattaataca gccatcgtca
     8821 tctttgctgg ttcggctgta cttttgaatg ataagtctat tgaaacaagt acagccctag
     8881 gtttgattgt tatgtttgca caattttcac agcagtacta ccagcctatt atccaagttg
     8941 cagcgagttg gggaagcctt cagttggcct ttactggagc tgaacgaatt caggaaatgt
     9001 ttgatgcaga ggaggaaatc cgacctgaaa aggctccaac cttcactaag ttgcaagaaa
     9061 gtgttgaaat cagtcatatc gatttttcat acttgcctga taaacctatt ttgaaagatg
     9121 tcagcatttc tgcccctaaa ggccagatga cagcagttgt tgggccgaca ggttcaggaa
     9181 aaacgactat tatgaacctc atcaatcgct tttatgatgt tgatgctggt ggtatttatt
     9241 ttgatggtaa agacattcgt ggctatgact tagatagtct tagaagcaag gtgggaattg
     9301 tattgcaaga ttcggtcttg tttagcggaa cgattcgaga caatatccga tttggtgtgc
     9361 cagatgctag tcaggaaatg gttgaggtag cagcaaaagc aacccacatt cacgactata
     9421 tcgaaagttt gcctgataag tacgatactc ttattgatga tgaccagagc atcttttcaa
     9481 cagggcagaa gcaattgatt tcaatcgctc gaaccctgat gacagatcca gaagttctca
     9541 ttctcgatga agcaacttca aacgtagata cggtgacaga aagcaagatt cagcatgcca
     9601 tggaggtggt tgtagcaggt agaactagtt tcgtcattgc ccaccgcttg aaaaccattc
     9661 tcaatgcaga tcagattatt gtccttaaag atggagaagt cattgaacgt ggtaaccacc
     9721 atgaactttt gaagctaggt ggcttttatt cagaactcta tcacaatcaa tttgttttcg
     9781 aataagaaag aagttgtcct atgtgggcag ctttttcttg tccataaaaa atgtttatca
     9841 cagccttaaa aaaaacatat tagacgaaag tcattttgag tgatatgata ggactatcgt
     9901 tagcattcga aaggagaggc atcatggcta gaacggttgt aggagttgct gcaaatctat
     9961 gtcccgtaga cgcagaaggc aaaatcattc attcatctgt atcttgtaga ttcgcagaga
    10021 tcattcgtca agtcggtggt ctccctttag tcattcctgt tggtgatgag tcagttgtac
    10081 gtgattatgt ggaaatgatt gacaaactca ttttgacagg aggccaaaat gttcatcctc
    10141 agttttatgg agagaaaaag accgtcgaga gcgatgatta caatctggtc cgtgacgaat
    10201 ttgaattggc actcttgaag gaagcgcttc gtcagaataa accaattatg gcaatctgtc
    10261 gcggtgtcca acttgtcaat gttgcctttg gtggaaccct caatcaagaa atcgaaggtc
    10321 actggcaagg actacctttc gggacatctc actctattga gacagtagaa ggaagcgtgg
    10381 tggctaagct atttgggaaa gaaagtcagg tcaactcagt ccatcgtcaa agcattaaag
    10441 atttggcacc taatttccgt gtaactgcta ttgattcaag agaccaaact attgaagcga
    10501 ttgagtctat cgacgagcac cgcattatcg gtttacagtg gcatccagag tttctggtta
    10561 atgaagaaga tggcaattta gaattatttg agtatttatt ggatgaactg taacaattgg
    10621 aacatctggt cgttctttct tttatttttt caaaattttt agaatgtggt attttacgca
    10681 aacgtttgaa ttctgataaa aattggagaa attcgacaaa aaaacttgaa aaaaacgaag
    10741 gtaagcgtta tgatagaaaa gaagaaatat tggaggaaga acatgtcaca tattaaattt
    10801 gattattcaa aagttttaga caaatttgtt gcaccacatg aagtggaata catgcaatca
    10861 caagtaacag cagcagatga attgatccgt aaaggaactg gtgctggtag cgacttcttg
    10921 ggatggttgg accttcctga aaaatacgac cgcgaagaat ttgaccgcat cttgaaagct
    10981 gctgagcaaa tcaagtcaga cagcgatgtt ttggttgtga tcggtattgg tggatcttac
    11041 cttggtgcaa aagcagcaat cgacttcttg aatcaccatt ttgctaactt gcaaacaaaa
    11101 gaagaacgca aagctccaca aatcctttac gcaggaaact caatctcatc tacttacctt
    11161 gctgacttgg tagagtatgt tgcagacaaa gacttctcag taaacgtaat ttctaaatca
    11221 ggtacaacaa ctgaaccagc gattgctttc cgtgtcttta aagaactctt ggttaagaaa
    11281 tacggtcaag aagaagctaa caaacgtatc tatgcaacaa ctgaccgcca aaagggtgct
    11341 gttaaggttg aagcagacgc taacggttgg ggaacatttg ttgttccaga tgatatcggt
    11401 ggacgcttct cagtattgac agccgttggt ttgcttccaa tcgcagcatc aggagctgac
    11461 ataaaagctc ttatggaagg tgcgaatgca gctcgcaaag actacacttc agacaaaatc
    11521 tctgaaaacg aagcttacca atacgcagct gttcgtaaca tcctttatcg taaaggctat
    11581 gcaactgaga tcttggtaaa ctatgagcca tcacttcaat acttctcaga atggtggaaa
    11641 caattggctg gtgaatcaga aggaaaagac caaaaaggta tctacccaac ttcagccaac
    11701 ttctcaactg acttgcactc acttggtcaa tttatccaag aaggaactcg tatcatgttt
    11761 gaaacagttg tccgtgttga caaacctcgt aaaaacgtgc ttattcctac tttggaagaa
    11821 gaccttgacg gacttggtta ccttcaagga aaagacgttg actttgtaaa caaaaaagca
    11881 actgacggtg ttcttcttgc ccacacagat ggtgatgtac caaacatgta tgtgactctt
    11941 ccagagcaag acgctttcac tcttggttac actatctact tcttcgaatt ggcaattgcc
    12001 ctttcaggtt acttgaatgc tatcaaccca tttgaccaac caggtgttga agcttataaa
    12061 cgtaacatgt ttgcccttct tggaaaacca ggatttgaag aattgagcaa agaacttaac
    12121 gcacgtctat aatagaagaa aagagtggtt tgcccactct ttttactctc tttatccata
    12181 gaaattggac tcagccaaga cttgtgatat aatatagaaa gcaaaaaggc agacgcctag
    12241 ataataggag aaactatgtc aaaagatatc cgcgtacgtt acgcaccaag tccaacagga
    12301 ctactacaca taggaaatgc tcgtacagca ttgtttaatt acttgtatgc gcgccatcat
    12361 ggtggaacat ttctcatccg tatcgaagat actgaccgta aacgccatgt cgaggatggt
    12421 gaacgttcac aacttgaaaa ccttcgctgg ttaggcatgg attgggatga aagtccagaa
    12481 tcacatgaga attatcgcca gtctgagcgt ttggacttgt atcaaaaata catcgaccaa
    12541 ctattagctg aaggaaaagc ctacaaatct tacgttacag aagaagagtt ggcagctgaa
    12601 cgtgaacgtc aagaagtagc tggcgaaaca ccacgctaca tcaatgaata ccttggtatg
    12661 agtgaagaag aaaaagcagc ttacatcgca gaacgtgaag cagcagggat catcccaact
    12721 gttcgtttgg ctgtcaatga gtcaggtatc tacaagtggc atgatatggt caaaggcgat
    12781 atcgaatttg aaggtggcaa tatcggtggt gactgggtta tccaaaagaa agacggttac
    12841 ccaacttaca actttgccgt tgttatcgat gaccacgata tgcaaatctc tcatgttatc
    12901 cgtggagatg accatattgc taatacacca aaacagctta tggtctatga agctcttggt
    12961 tgggaagctc cagagttcgg tcacatgacc ttgattatca actctgagac tggtaagaag
    13021 ttatctaaac gtgatactaa tacacttcaa tttatcgaag attaccgaaa gaaaggttac
    13081 cttccagaag cagtctttaa ttttattgct cttcttggtt ggaacccagg tggtgaagat
    13141 gagattttct ctcgtgaaga actcattaaa ctttttgatg aaaaccgcct cagcaagtca
    13201 ccagcagcct ttgatcagaa aaaactagac tggatgagca atgattatat caagaatgca
    13261 gaccttgaaa ccatctttga aatggcaaaa ccattcttag aggaagcagg ccgtttgact
    13321 gacaaggctg aaaaattagt tgagctctat aaaccacaaa tgaaatcagt agatgagatt
    13381 atcccattga cagatctttt cttctcagat ttcccagaat tgacagaagc agagcgcgaa
    13441 gtcatgacgg gtgaaacagt tccaacagtt cttgaagcat tcaaagcaaa acttgaagcg
    13501 atgacagatg ataaatttgt gacagaaaat atcttcccac aaattaaagc agttcaaaaa
    13561 gaaacaggta ttaaagggaa aaatcttttc atgcctattc gtatcgcagt ttcaggcgaa
    13621 atgcatgggc cagaattacc agatacaatt ttcttgcttg gacgtgaaaa atcaattcag
    13681 catatcgaaa acatgctaaa agaaatctct aaataaagag gatacaataa tggacatctg
    13741 ggaaaagatg tacgaagaag cacagaaact atacaatcca catgaagtat cagactttgt
    13801 ttatgccaat catgttgtag ctgcagtaga agcagaagat ggacaaatat ttacaggatt
    13861 ctgtatggag ggaacctgtg gtgttttcca tctctgcgca gaacgggcgg ccctcttcaa
    13921 tacgtaccaa ttttcaggac aaactaaggt taagaaagta ttagcctttc gagacaaacc
    13981 accttatggt ggaagttcag ccatgccttg cggtgcttgt agagaattcc ttttagagct
    14041 taatgctgaa aataaagatg cagaattcat gatggactat aatataagaa aaacagttaa
    14101 agtcgcagaa ctaatccctt attggtgggg agaagaacgt gcttctaagt ttaatgagcg
    14161 atagaagagt cagtataatt ctggcttttt ttactataag ttgaaaaaat
//
LOCUS       DAVBEO010000053        14056 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 009
            SAMEA1678075-rid20185393.denovo.053, whole genome shotgun sequence.
ACCESSION   DAVBEO010000053 DAVBEO010000000
VERSION     DAVBEO010000053.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678075
            Sequence Read Archive: ERR226392
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 14056)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14056)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980207.1
            Genome Coverage       :: 150x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:50:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 72 of 147
            Pseudo Genes (incomplete)         :: 72 of 147
            Pseudo Genes (internal stop)      :: 42 of 147
            Pseudo Genes (multiple problems)  :: 32 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14056
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678075-rid20185393.denovo.053"
                     /strain="KS 009"
                     /db_xref="taxon:1313"
     gene            98..1357
                     /locus_tag="VQ543_001736"
     CDS             98..1357
                     /locus_tag="VQ543_001736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRZ/ATZ family protein"
                     /protein_id="HET2612419.1"
                     /translation="MKVFQHVNIVTCDQDFHVYLDGILAVKDSQIVYVGQDKPAFLEQ
                     AEQIIDYQGAWIMPGLVNCHTHSAMTGLRGIRDDSNLHEWLNDYIWPAESEFTPDMTT
                     NAVKEALTEMLQSGTTTFNDMYNPNGVDIQQIYQVVKTSKMRCYFSPTLFSSETETTA
                     ETISRTRSIIDEILKYKNPNFKVMVAPHSPYSCSRDLLEASLEMAKELNIPLHVHVAE
                     TKEESGIILKRYGKRPLAFLEELGYLDHPSVFAHGVELNEREIERLASSQVAIAHNPI
                     SNLKLASGIAPIIQIQKAGVAVGIATDSVASNNNLDMFEEGRTAALLQKMKSGDASQF
                     PIETALKVLTIEGAKVLGMENQIGSLEVGKQADFLVIQPQGKIHLQPQENMLSHLVYA
                     VKSSDVDDVYIAGEQVVKQGQVLTVEL"
     misc_feature    1433..1568
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00557"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L10 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00557"
     gene            1607..2107
                     /locus_tag="VQ543_001737"
     CDS             1607..2107
                     /locus_tag="VQ543_001737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001287276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L10"
                     /protein_id="HET2612420.1"
                     /translation="MSEAIIAKKAELVDVVAEKMKAAASIVVVDARGLTVEQDTVLRR
                     ELRGSEVEYKVIKNSILRRAAEKAGLEDLASVFVGPSAVAFSNEDVIAPAKILNDFSK
                     NAEALEIKGGAIEGAVASKEEILALATLPNREGLLSMLLSVLQAPVRNVALAVKAVAE
                     SKEDAA"
     gene            2183..2551
                     /gene="rplL"
                     /locus_tag="VQ543_001738"
     CDS             2183..2551
                     /gene="rplL"
                     /locus_tag="VQ543_001738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7/L12"
                     /protein_id="HET2612421.1"
                     /translation="MALNIENIIAEIKEASILELNDLVKAIEEEFGVTAAAPVAVAAA
                     DAADAGAAKDSFDVELTSAGDKKVGVIKVVREITGLGLKEAKELVDGAPALVKEGVAT
                     AEAEEIKTKLEEAGASVTLK"
     gene            2738..2908
                     /locus_tag="VQ543_001739"
     CDS             2738..2908
                     /locus_tag="VQ543_001739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001168336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2612422.1"
                     /translation="MQKEGQSSRQFVKSHLMTIMGVDIVKATQLVDEMEQVGLIRFDE
                     FGNVGILVLEGQ"
     gene            2908..3156
                     /locus_tag="VQ543_001740"
                     /pseudo
     CDS             2908..3156
                     /locus_tag="VQ543_001740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017648301.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
     gene            3170..3527
                     /locus_tag="VQ543_001741"
                     /pseudo
     CDS             3170..3527
                     /locus_tag="VQ543_001741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001134542.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            3520..3900
                     /locus_tag="VQ543_001742"
     CDS             3520..3900
                     /locus_tag="VQ543_001742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HET2612423.1"
                     /translation="MIDLYLSKNRQRNQLLLDFFQNYGIEVSCHSVSEMTKDKLIEMM
                     SYSSDCFEFLSPNLLRFKNRDNLRLTDFVEIILKNPELTIRLPLAVSNKRVYPSLNLE
                     EARALLPRDTKQLIYMAQTHYLSN"
     gene            3913..4056
                     /locus_tag="VQ543_001743"
     CDS             3913..4056
                     /locus_tag="VQ543_001743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2612424.1"
                     /translation="MAERFWENLSIILAERNISWIELTRKMFAGEFHYPSELNRLYQK
                     IRH"
     gene            4149..4736
                     /locus_tag="VQ543_001744"
     CDS             4149..4736
                     /locus_tag="VQ543_001744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000821297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET2612425.1"
                     /translation="MKRIIPVYIFQQVNVLLVSLYLLKFLCIGELTILQILYGSSLIS
                     FLWMYGQRKQAHKVNMKSRMKWLGVEFVSLLIISLCFSLIHAQGSTNQANLIGLQHQI
                     PWFSFLLFLINASMVEEFLYREILWNLVRKLDIRVALTSVLFALAHHTGTILAWCLYV
                     SLGMFLGMVRYKSDLWGSMGLHLVWNLLVYSLLLF"
     gene            4938..5075
                     /locus_tag="VQ543_001745"
     CDS             4938..5075
                     /locus_tag="VQ543_001745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004264816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SapB/AmfS family lantipeptide"
                     /protein_id="HET2612426.1"
                     /translation="MAEEVLNLQLVSVQVDETDEVDGMRFSTFSTNRCGNWSAFSWEN
                     C"
     gene            5254..7863
                     /locus_tag="VQ543_001746"
     CDS             5254..7863
                     /locus_tag="VQ543_001746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000386153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lanthionine synthetase"
                     /protein_id="HET2612427.1"
                     /translation="MDYNFNLEHPFFFTNNDYSTDTSIKYQVSLPFNWHEVMNNDEWV
                     YQYPIGKFVERQGWKIHISSEYNSSHELLQDVAKICHEMRIPFKHLSTEDKFIMRNGK
                     LVSRGFSGKFITCYPNQNELESVLQRLESALKQYNGPYILSDKRWDEAPIYLRYGVFR
                     PSRDDEKKVAIDELIVGDEVVKDERLPVFKIPKGIVPPDFLNKWLDKKDKKQGDFPFI
                     IDNAIRFSNSGGIYNARLKEDGKKIILKEARPYTGLGFDGTYSSEKLASECKALKILN
                     EWSETPKIYWHGKIWEHTFLGIEHMKGVPLNRWVTNNFPLYEVVDKTKDYLLRVSKIV
                     EKLIDLTNKFHSENVYHQDLHLGNILVKDEDEISIIDWEQAVFSNDEKVVHKVAAPGF
                     RAWRETLPSEIDWYGIRQIAHYLYMPLVTTSDLTYNYVSQTRIEGKKLFESLGYTREH
                     IDYVESLLSYLDSKCPQIENISRKKVLKPMHEIRTIESEQDIQDFIIKLLRGFTLTYG
                     QWRKEFQSRFFPVHYYGLNFNQGIAFSDLAILWSYQQLAKKVKNFKFDDYYEIRTQVI
                     NEAVNNFKKSSLSGLFDGKIGTIWLIYEFGEIDRAVELFTTHFIEIFENSQNKNLYSG
                     QAGILLVGLYFLSKGEIDNKLGEEILIRLREYTLNYIENPETFCKVGASDVQSNDPYE
                     NFGGLLYGHAGVAWLFGEAYKLTGESIYKNGLELAVDKELVAYKVDSNNSLQYSQGHR
                     LLPYLATGSAGLLLLINRNKEILSSKYLKYLTSLERATDVVFCVLPGLFNGFCGLEVA
                     NNIYSDIDDNFSGQKKLIEQLYRYLCVIEEGFVIAGDNGLKITTDIASGFAGVAIGLV
                     SIMDNKLTILPQI"
     gene            7896..9836
                     /locus_tag="VQ543_001747"
     CDS             7896..9836
                     /locus_tag="VQ543_001747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004263477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S9 family peptidase"
                     /protein_id="HET2612428.1"
                     /translation="MNQSNEIFLNTIQEKTHYKRSISSSFQELKKWNSLIFRRGRYWY
                     QFDNWSIPNTGVIKEWYVEDNDWIPKVSSSSLDNSNSLKIVFDVEKYTLPDDSILQDV
                     RISSDESYIVLVVSSLRSTNLIGIKKYTMEELFIIEDISVESSFYLGKFGVMYTRSKE
                     YGRPSKLFYKSFDSFTEEELFEENECSFRLKIVHIDSNNCFVKSVDFQKGRIFLYSFD
                     RTGFVRHSYTETVAPTPRDIALFSTEKAQYFLGLSSTEEKKDQLILRETSSGDRVSIT
                     IPYQDRARRVHCIGRYILLDCSNAANSVFYLATFKNNSLRELSVNKITFDEKTTLYEN
                     SFSDRVLLFLERRTFYEKILSFDLIENTLKTEFERPIIKSNNTKYFSKVIWTKKDSYD
                     VSIPISLFWKSEDTDELPRRKKCILSVYGAYGKNDNSDLDEIMLSIIDAGFIYAIVHV
                     RGGGYLGGEWYRSGKALNKWNSIRDFIEGVNYLRENDVIDSKRLGLITSSAGGIIAGA
                     VLNEEKNLLQSILLFSPFINPYDTLQNPNDPLSKTEIAEWGDIRDPEVKAYIKSYSPM
                     QNIEKARDSNTVIVNILGEKDPYINNNEVIEWSKKLNSIGVKSLLYLNKAAGHGGFTP
                     SDVLLMIDTLNYFFEEVGRNNL"
     gene            9833..11440
                     /locus_tag="VQ543_001748"
     CDS             9833..11440
                     /locus_tag="VQ543_001748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2612429.1"
                     /translation="MNYLKFIKKTKLILMGILIFLSSFNGVLLSGIIVYAGSLNQTSS
                     FSDVLRFGAISILGWSAIYISNYYLEVTEASITKDINVKIKQGYFREQYLSSEMVKDY
                     SSIISVLSNDLRLIEENYFRQIFEIISSILLFIVSLSFMLYLNFLVSIIFIVLSALPI
                     IVPVFMKKMLSNSANEYSNSNAEYTHIIKEIFNGFKTLKSYSVTKEIISLSDKKLDKL
                     EDSTFNLKRSEVLSKLVAVLISGFCFLVPLVVGCYFVIYHKSLSFSELIGIFLANDKV
                     LGPIQSIAYSLNKINTTKDLRKPFLKYLSGEKNFIDAEHDNNGLYTSSIDEIHMKDVV
                     YSITPENKLSIDFSFKSPFRVLLTGTSGSGKTTILNLINGSLKPQKGYVNLLSHGKKS
                     SDSIPTVDQTPYIFDTTIRENVTLFQNEYFSDDQIIEVLKKVNLYEELEKIDILNYQC
                     GENGSNLSGGQKQKIALARALIRNNKVYLFDEISANLDNDNSNSIHDILFNLGISFIE
                     VSHHYDLNDKRYTDIYKLENGTLFKIK"
     gene            11455..12195
                     /locus_tag="VQ543_001749"
     CDS             11455..12195
                     /locus_tag="VQ543_001749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000356590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2612430.1"
                     /translation="MDKDYILKVKGLYHQFLLGNNKTLQVLKNVSLSASRGEFISILG
                     ISGSGKSTLLKCISSLLEPTSGEVILNGINPYKIRNAKLSSIRRNEVSFIFQAYNLIP
                     SLPVIENIALPLRLSQKKLTIKNVENLLKRMKFNAGLNDFVGTLSGGEQQKVAIARAV
                     IADSDIIFADEPTGALDSVSREVIFELLRELVGAGKCVIMVTHDIELASKTDRALILK
                     DGKIFKELHRPSGEELYKILEVQSTTEE"
     gene            12198..13517
                     /locus_tag="VQ543_001750"
     CDS             12198..13517
                     /locus_tag="VQ543_001750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000945307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2612431.1"
                     /translation="MLRLVYYQFLHNKKQWLGVSPVIFVSSLVMGLAVNGVINVENNS
                     QVFVGLPDPKPIFMFPIVFGGVTLFFVLSNIINMLVEIFRDDYELLEVLGASLLQLSF
                     LVGGQIFIISSIISFIAYLCSIFVTSNYYYFLQYFFGENILPDIQFQTSAVGCIITVV
                     LISFLAFLSGCFYTFKKIRNRKSSKIRHVLSIVKRILLLAGFSVIWLLSLQQIFQDST
                     ILAKAQIIFNIVILDIVIIYQLSPFIQSCFIKLLSIIIFRNNFMFIASKWNLLYRKPY
                     IKSISAAITGAILLISSFQMISQNILSQFQDDSDLELKVAFIVYVGAPILIVLANIIS
                     IAFLSSHQERIEIQQFEILGTSNYQMVKIKVGEAIFLTFVTSLIAFLLNIKIMALIYY
                     SLEDVLIDDMNLLGLILPNFIVSIILFILIFITKSSYFIFKNAKIIS"
     gene            13651..13788
                     /locus_tag="VQ543_001751"
     CDS             13651..13788
                     /locus_tag="VQ543_001751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004264816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SapB/AmfS family lantipeptide"
                     /protein_id="HET2612432.1"
                     /translation="MAEEVLNLQLVSVQVDETDEVDGMRFSTFSTNRCGNWSAFSWEN
                     C"
BASE COUNT         4696 a         1962 c         2778 g         4620 t
ORIGIN      
        1 agatagaact gacgaagtca gtaaccacac ctacggcaaa gtgaatctga agtggtttga
       61 agagagtaca acttgtcttt tagaaaagga gcctataatg aaagtctttc agcatgtaaa
      121 tatcgtgact tgtgatcaag atttccatgt ttatcttgat ggaatcttag cagtcaagga
      181 ttctcaaatc gtctatgtcg gtcaagataa gccagcgttt ttagagcaag ctgagcagat
      241 tatagactat cagggagctt ggattatgcc tggtttggtc aattgtcaca cccattctgc
      301 aatgacaggt ctgagaggga tccgagatga cagcaatctc catgaatggc tcaatgacta
      361 tatctggcca gcagaatctg agtttactcc cgacatgact accaatgcgg tcaaagaagc
      421 cctgacagag atgctccagt caggaacaac aacctttaac gatatgtata atcccaatgg
      481 tgtggatatc cagcaaattt atcaggtggt gaaaacttcc aagatgcgtt gttatttttc
      541 tccgactctc ttttcttcag agacagaaac aactgctgag actataagca gaactcgatc
      601 catcatagac gaaatcttaa aatataaaaa tccaaatttc aaggttatgg tagcacctca
      661 ttctccgtat agctgcagta gagacttgct ggaagcgagt ttggaaatgg caaaagagct
      721 aaatattccg ctccatgtcc atgtggcgga gaccaaggag gagtcaggaa ttatcctcaa
      781 acgatacggc aaacgccccc ttgcttttct tgaagaactg ggttatttag atcatccgtc
      841 cgtatttgct cacggggtcg aattaaacga gagagaaatt gaacgcttgg catcttctca
      901 agtggctatc gcccacaatc ctatcagtaa cctcaaactg gcatcaggaa ttgctccaat
      961 tatccagatc caaaaagcgg gagtagcagt cggaattgcg actgactcgg ttgcttccaa
     1021 taacaatcta gatatgtttg aggaaggaag gactgcagct cttcttcaga agatgaaaag
     1081 tggggatgcc agccagtttc caatcgaaac agctctcaag gtactgacaa tcgaaggggc
     1141 taaggtcctt ggaatggaaa atcagatagg aagtctggaa gtcggcaagc aagcagattt
     1201 tctggtcatt caaccacaag ggaaaattca tctccaacct caggaaaata tgctgtctca
     1261 cctggtttat gcagttaaat ctagtgatgt agatgatgtt tatatcgccg gagaacaggt
     1321 tgttaagcaa ggtcaagtcc tgacagtaga actttaaaag aaaaatcacg aaaaatttta
     1381 aaaaaagttt gcaaaaatct tgcattcttt ttttgactat gctatactta tatacggttt
     1441 aaaaaaactg cctaagacag taggggagct cgactcataa atatcctacc gaggacaaga
     1501 cgtatcatgt aaaaagaagc gtattgtact ttcgtgtcta ggtttgggcg cgtttttctt
     1561 tttgaaaaat tccccaagca aaataattac ggaggtgaac acactaatga gtgaagcaat
     1621 tattgctaaa aaagcggaac tagttgacgt agtagctgaa aaaatgaaag ctgctgcatc
     1681 tatcgtcgtt gtagacgctc gtggtttgac agttgagcaa gatacagttc ttcgtcgcga
     1741 gcttcgtgga agcgaagttg agtataaagt tattaaaaac tcaatcttgc gtcgtgcagc
     1801 tgaaaaagct ggtcttgaag atcttgcatc tgtatttgtt ggaccatctg cagtagcatt
     1861 ttctaatgaa gatgttatcg caccagcgaa aatcttgaac gacttttcta aaaacgctga
     1921 agcacttgaa attaaaggtg gtgcaatcga aggcgctgtc gcatctaaag aagagattct
     1981 tgcacttgca actcttccaa accgcgaagg acttctttct atgctccttt ctgtacttca
     2041 agcgccagtg cgcaacgttg ctcttgcagt caaagcggtt gcagaaagca aagaagacgc
     2101 ggcttaatct taagctacac agcgtagcct agctacgaaa aaaactatta taaaatttaa
     2161 aacttatttg gaggaaataa caatggcatt gaacattgaa aacattattg ctgaaattaa
     2221 agaagcttca atccttgaat tgaacgacct tgtaaaagct atcgaagaag aatttggtgt
     2281 aactgcagct gctcctgtag ctgttgctgc agctgatgca gctgatgctg gtgctgctaa
     2341 agattcattc gacgttgaat tgacatctgc aggcgacaaa aaagttggcg ttatcaaagt
     2401 tgtacgtgaa atcactggtc ttggtcttaa agaagctaaa gaacttgttg acggtgcacc
     2461 agcacttgtt aaagaaggcg ttgcaactgc agaagctgaa gaaatcaaaa ctaaattgga
     2521 agaagctgga gcttcagtta ctcttaaata atagagtatc gcaatttgat tgcggaatcc
     2581 ctatttacca gtctttgaga gcgataagcg attgatagaa actgataaat tgatttggtt
     2641 tcctgccaaa aattctttgg caggattttt gttttaataa actttcgggg gtagacacta
     2701 gattgtctac cccttttttt gtgtttcgga ggtaattatg caaaaggaag gacagtcatc
     2761 acgtcaattc gtgaagagtc atctcatgac tatcatggga gttgatattg taaaagcaac
     2821 tcagttagtt gatgaaatgg aacaagtagg tttaatccga tttgatgaat ttggaaatgt
     2881 tggaatttta gtcttggagg gacaataatg aagtgtatta ccgctaatca atatcagaca
     2941 tcagagcgtt attataagct ccccaaactt ttatttgaga gtgaacggta taagaatatg
     3001 aaactggagg ttaaggtggt ttactcagtt ttaaaagatc ggttggagtt gtctttgagc
     3061 aaaggttgga ttgatgagga tggggctatt tatttgattt attccaattc aaatttgatg
     3121 gcacttttag gctgttcaaa gtcaaaatta ctctccatgt gagtttgaag tgacattttt
     3181 agatgattac cataaaaaac ataactaccc actattttac gaatcctatc ttcaaaacgt
     3241 tatggaattc cttgaaagtc aagacataaa gaatggggtt gatgcctttg tagatgatca
     3301 tcaaaatctc gtttttgttt tatatggaca aggctatcga gccgagggaa aagagggaat
     3361 acttacaacc caagtaactg taaaagctta tgatgaagac aagaaaccga ttaacttcgc
     3421 aaatttatta gattccttaa tttattagat tccttaattt attagattcc ttaatcgtgt
     3481 cagaatatca aatggaaccg aatctttggg aggtctccca tgattgatct ctatctaagt
     3541 aaaaatagac aaagaaatca acttctttta gatttcttcc aaaactatgg catagaggta
     3601 tcttgtcatt cagtttctga aatgacaaag gacaaattaa ttgagatgat gagctattct
     3661 tcagattgtt ttgagttttt atctcccaat ttattacgat ttaagaaccg tgacaatcta
     3721 agattaacgg atttcgttga gataatttta aaaaatcctg aactaaccat cagacttcct
     3781 cttgcggttt caaataagcg agtttatcca agtctgaatt tggaagaggc tagagctcta
     3841 ttgccaagag atacgaaaca attgatttac atggcgcaaa cacattattt atctaactaa
     3901 aggagaagca atatggctga acgattttgg gagaacttgt ccattatttt ggctgaaaga
     3961 aatatcagct ggattgagtt aaccagaaaa atgtttgcgg gagagtttca ctatccaagt
     4021 gaattgaatc gtttgtatca aaagattcgc cactagaaga tggaacaatg aatgcctcaa
     4081 agtccatggg tagaaaggat tgtgcaggta ttagatttag attatgaaga tttatttcgg
     4141 aggtaactat gaaaagaata attccagttt atatattcca acaagtaaat gtcctattgg
     4201 tatctctata cttattgaaa tttctttgta tcggtgagtt aactatacta cagattctct
     4261 atggttcgtc actcatttct tttttatgga tgtatggcca acgcaaacaa gcgcataagg
     4321 tcaatatgaa atctaggatg aaatggcttg gtgttgaatt tgttagccta ctgattataa
     4381 gtctatgttt tagtctgatt catgctcaag gaagcacgaa tcaagcaaac ttaattggcc
     4441 ttcaacatca aattccttgg ttttcatttt tattgttctt aatcaatgcg agtatggttg
     4501 aagaatttct gtatcgagaa attttatgga atttggtcag aaaattagat atcagagttg
     4561 ctttgacaag tgttttattt gccttagcac atcatacagg aaccattcta gcttggtgtt
     4621 tgtatgtttc acttgggatg tttttaggta tggtgcgcta taaatctgac ttatggggca
     4681 gtatgggact acatttggtg tggaacctac tagtttatag tttgctgctt ttttaaaata
     4741 ggtgacctga tttttaggta acttctaaaa ctaacttcca gttttgggag agagatggaa
     4801 gttactttga aaagttacgg aaacattatt ttctatgtga caacattgta taattgcttg
     4861 cattttactg gtggagagag tataatgagg gtggataaag tacttaatcc caaaaattta
     4921 aataggagga gctagctatg gcagaagaag tattaaatct tcaattagta tctgttcaag
     4981 ttgacgaaac agatgaagtt gatggaatgc gatttagtac attcagtaca aatcgttgcg
     5041 gtaactggag tgcttttagt tgggaaaatt gttaattcat ttaaattgta aactttagag
     5101 attctctgga gttatggatg tcgttccaat atgtgcacgt tggaatgtta gtgcttatat
     5161 ggggagaatc caaaggattc tcccttttta tttaaataag tctgtctagc tatagatata
     5221 ttaagtttga taaaatttct tggagatttt gttatggatt ataatttcaa tttggagcat
     5281 cctttctttt tcactaataa tgattatagt acagatacta gcataaagta ccaagtaagt
     5341 ctgcctttta attggcacga agtaatgaat aatgatgagt gggtttatca ataccctatt
     5401 ggaaaatttg ttgaaagaca agggtggaaa atacacatta gttcagagta taacagttca
     5461 catgaattgt tacaagatgt agcaaaaatt tgccatgaaa tgcgaattcc atttaaacat
     5521 cttagtacag aagacaaatt tatcatgcga aacgggaaat tggttagtcg aggattttct
     5581 ggtaaattta ttacatgtta tccaaatcaa aatgaattag agtcggtttt gcaaaggtta
     5641 gaaagtgcct taaagcaata taatgggcca tatattttaa gcgataaacg ttgggatgaa
     5701 gcaccaatat atctgaggta tggtgtgttt aggccgtcaa gggatgatga aaagaaggtt
     5761 gctattgatg aattaattgt tggcgatgaa gttgttaaag atgaacgttt accagtattt
     5821 aaaattccaa aaggtatagt gccccctgac tttttgaata aatggcttga caagaaagat
     5881 aaaaaacagg gagactttcc ctttattata gataatgcaa ttagattttc aaacagtggt
     5941 gggatatata atgctaggct aaaagaagat gggaaaaaaa taattttaaa agaggctaga
     6001 ccgtatacag gtctaggatt tgatggtact tattcttcag agaaattagc ttcggagtgc
     6061 aaagcactaa aaattctaaa tgaatggagt gagacgccta aaatatactg gcacggtaag
     6121 atctgggagc acaccttctt aggaattgaa catatgaagg gcgttccact aaatagatgg
     6181 gttaccaata attttccttt atatgaagtt gttgataaga ccaaagatta tctattgaga
     6241 gtttcaaaga tagtagaaaa actcatcgat ttaacgaata agtttcattc tgaaaatgta
     6301 tatcatcaag atttacattt aggaaatatc ttggttaagg atgaagatga gattagtata
     6361 atagactggg aacaggctgt cttttcaaat gatgaaaaag ttgtacataa agttgcagcc
     6421 cctggtttta gagcatggcg agaaacactt cccagtgaga tagattggta tggtattaga
     6481 caaatagctc attatttata catgccacta gtaactacat cggatttgac atacaactat
     6541 gtaagtcaaa ccaggataga aggaaaaaaa ctatttgagt ctttgggtta tacaagagaa
     6601 catatagatt atgtagaaag tttattgtca tatctagatt ctaaatgtcc acagattgag
     6661 aatatttcca ggaaaaaagt tttaaaaccc atgcatgaga ttagaactat cgagagtgag
     6721 caagatatac aagattttat tataaaatta ttgagagggt ttacgctaac ttatggacag
     6781 tggcgtaaag aatttcaatc aagattcttc ccagttcatt attatggtct gaattttaat
     6841 caaggaattg cgttttcaga tttagctatc ctttggagtt atcaacaact agctaagaaa
     6901 gtaaaaaatt tcaagtttga tgactattat gagattcgaa cacaggttat taatgaggca
     6961 gtaaataatt ttaagaaatc gtccctttct ggtctttttg atggtaaaat tggtacaatc
     7021 tggctcattt atgaatttgg ggagatagat cgggcagttg aactttttac aactcatttt
     7081 atagagatat ttgagaattc acaaaataaa aatttatata gtgggcaggc tggaatttta
     7141 ctggttggac tgtattttct tagtaaaggg gaaattgata ataaactagg agaagaaata
     7201 ctaattaggc ttagagaata tactttaaat tatatagaaa atccagaaac tttttgtaaa
     7261 gttggcgcta gtgatgttca gagtaatgat ccttatgaga attttggtgg attactatat
     7321 ggtcacgcag gggtagcttg gctcttcggt gaagcttata aattaactgg tgaaagtatc
     7381 tataaaaatg gtctagaatt ggctgtagat aaagaattag ttgcttataa agtagatagt
     7441 aataattcat tgcagtacag ccaaggtcat agattactac catatctagc aactggaagt
     7501 gctggcctgc ttttacttat taatagaaat aaagaaatct tgtcaagcaa atacttaaaa
     7561 tatttaactt ctttagagag ggcaactgat gtagtttttt gtgtattacc aggtttattt
     7621 aacggatttt gtggtcttga agttgctaat aatatatata gtgatatcga tgataacttt
     7681 tcaggacaaa agaaattaat tgaacaactt tatagatatt tgtgtgtaat tgaagaagga
     7741 tttgttattg cgggagataa tggtttaaag ataacaacag atattgcttc gggatttgcg
     7801 ggtgttgcaa ttggattggt atcaataatg gataataaat tgacgattct tcctcaaata
     7861 taatatttag ataccattat taaggggtca tacttgtgaa tcagagtaat gaaatatttt
     7921 taaatacaat acaggaaaaa acacactata agaggtctat ctcttcatca tttcaggaat
     7981 taaaaaaatg gaattctttg atatttagga gagggcgata ttggtaccaa tttgataatt
     8041 ggagtatacc caatactggt gtaataaagg aatggtatgt cgaagataat gactggattc
     8101 ctaaggttag ttcttccagt ttagacaatt caaattcact taaaattgtc tttgatgtgg
     8161 aaaaatatac tttgccagat gatagtatct tacaggatgt taggatttca tctgatgaga
     8221 gttatatagt tttggttgta tcctcactgc gtagcactaa tttaattgga ataaaaaaat
     8281 atactatgga agagttattt atcattgaag atatttcagt agaaagttcg ttctatttgg
     8341 gtaaattcgg tgttatgtat actcgctcca aagagtacgg gaggccaagt aagttattct
     8401 ataaatcttt tgatagcttt acagaagagg aactgtttga agaaaacgaa tgctcttttc
     8461 gattaaaaat agtccacatt gatagcaata attgttttgt aaagtcagta gactttcaga
     8521 aaggcaggat ttttctatac agtttcgacc ggacgggttt tgttagacac tcttacacag
     8581 aaacggtagc cccaacacct agagatatcg ctctatttag tacagaaaaa gcacagtact
     8641 ttcttgggct ctcttcaact gaagaaaaga aagatcaact aattctaagg gaaacttctt
     8701 cgggagacag agtttctatt actataccat atcaagatag ggctagaaga gttcactgta
     8761 taggacgtta tatcctttta gactgttcaa acgcagcgaa ttccgtcttt tatcttgcta
     8821 catttaaaaa taatagtttg agggagttga gtgttaataa gataacattt gatgaaaaga
     8881 caacacttta tgaaaattca ttttctgatc gtgttcttct gtttttagag aggagaactt
     8941 tttacgaaaa aatacttagt tttgatttaa tagaaaatac attaaaaact gaatttgaaa
     9001 gacccatcat aaaatcgaat aatactaaat atttttctaa ggtgatttgg actaaaaaag
     9061 acagttatga tgtaagcata ccgatttctt tattttggaa aagtgaagat acggatgagc
     9121 tcccaagaag aaaaaaatgt attctaagtg tctatggggc ttatggtaag aatgataatt
     9181 ctgatttaga tgaaattatg ttatctataa tagatgcagg ttttatttat gctatagttc
     9241 atgtaagagg tggaggctat ttgggtggtg aatggtatcg ctcaggaaag gcgttaaaca
     9301 aatggaattc tatcagagat tttattgagg gagtaaatta tttaagggaa aatgatgtaa
     9361 ttgacagtaa gcgattaggt ttaataactt ctagtgcagg tggaataatt gctggtgcgg
     9421 tgttgaacga ggaaaaaaat ttattgcaaa gcattctctt attttcgcca tttataaatc
     9481 cttatgatac acttcagaat ccaaatgatc ctctttctaa gaccgaaata gcagagtggg
     9541 gagatattag agaccctgaa gtaaaggctt atataaagtc atattcgcct atgcaaaata
     9601 ttgaaaaggc acgagactca aatactgtta tagttaatat tttgggtgag aaagacccat
     9661 atattaataa taacgaagtg atagagtggt caaagaaatt aaattctatt ggagttaaaa
     9721 gtttgttgta tttaaacaaa gcagctggtc atggaggttt tactccatca gatgttctct
     9781 taatgattga tactttaaat tatttctttg aagaagtggg aaggaataac ttatgaatta
     9841 tttaaaattt ataaaaaaga ctaaacttat attaatgggg attttaatat ttctatcttc
     9901 gtttaatggt gtcttgctct caggaattat tgtatatgca ggtagtttaa atcagacttc
     9961 ctcattttct gacgttctaa gatttggtgc tataagtatt ctgggttggt cagcaatcta
    10021 tatatcaaat tactatttag aagtaacgga agcatcaata acgaaagata taaatgtaaa
    10081 aattaaacaa ggatatttta gagaacagta tctttcttct gaaatggtta aagattactc
    10141 atctattatt tcagttttgt caaatgattt gagattaatc gaagaaaact attttagaca
    10201 aatttttgaa ataatttctt caatattgtt gttcatcgtc tctctaagtt ttatgcttta
    10261 tttaaacttc ctagtttcaa taatatttat tgtattatca gcattgccga ttatagtacc
    10321 tgtctttatg aagaagatgt tgtctaattc agctaatgag tactctaaca gcaatgcaga
    10381 gtatactcac ataataaaag aaatttttaa tggttttaag acattaaaat cttattctgt
    10441 tactaaagaa ataattagtt tgtcggataa aaagttggat aaactagaag attctacttt
    10501 taatttgaaa cgatcagagg ttctttcaaa attggttgca gtactaattt caggtttttg
    10561 ctttctagtt cccttggttg taggatgtta ttttgtaatt tatcataaaa gcctttcttt
    10621 tagtgaactg ataggtattt tcttagcaaa cgataaagtt ttagggccga tacaatcaat
    10681 tgcctattca ttaaataaga taaatacaac caaagattta aggaaaccgt ttttaaaata
    10741 cttaagtgga gagaagaatt ttatagacgc tgaacatgat aataacggac tgtatacttc
    10801 atcaatagat gagatacaca tgaaagatgt tgtatattct attacaccag aaaataaatt
    10861 aagtattgac ttctcattta agtcaccatt tagggtatta ttaacaggaa cttctggtag
    10921 tgggaaaaca acgattttaa atttaattaa tggttcttta aagccacaaa aaggttatgt
    10981 aaatttgtta tcacatggga aaaagagttc agattcaata ccaacagttg atcagacacc
    11041 atatattttt gacactacta ttcgtgagaa cgtaacttta tttcaaaatg aatatttttc
    11101 agatgatcag ataattgagg tgttaaaaaa ggtaaatcta tatgaagaat tagaaaagat
    11161 agatatacta aattatcaat gtggtgaaaa tggtagtaat ttgtctggag gtcaaaaaca
    11221 aaaaatagct ttagctagag ctctgattag aaataataaa gtgtacttat ttgacgaaat
    11281 atcagctaat ttagataatg ataattcaaa ttccatacat gatattctgt tcaatttagg
    11341 tatttcattt attgaagttt cacatcatta tgacttaaat gacaagagat acactgatat
    11401 atataaattg gaaaatggaa cacttttcaa aattaagtga ttggaggcaa gaatatggat
    11461 aaagattata tattaaaagt gaaagggctg tatcatcaat ttttactagg aaataataaa
    11521 acgttgcaag tgctgaaaaa tgtttctctt tctgcttcga gaggagaatt tataagtatt
    11581 ctaggaatta gtggttctgg aaagtcaact ttattaaaat gtatttctag tttgcttgaa
    11641 ccaacaagtg gggaagtaat tttaaatgga atcaacccct ataaaatcag aaatgcaaaa
    11701 ttgtcaagta taagacgtaa cgaagtatct tttatatttc aagcatacaa tttaatacct
    11761 tccctgccgg taatagaaaa tatagcactt cctttgcgat tatcacaaaa aaaattaact
    11821 attaaaaatg tagaaaactt actcaaaaga atgaagttta atgctggctt aaacgatttt
    11881 gttggaactc tgtctggtgg agaacaacag aaggttgcta tagctagagc ggttattgct
    11941 gatagtgata taatatttgc tgatgagcca actggggctt tagacagcgt ttctcgtgaa
    12001 gtaatttttg aattattgag agagttagta ggggcgggta agtgtgtaat tatggtaacg
    12061 cacgatatag aattggcctc gaaaactgat cgtgcattaa tattgaaaga tggaaaaatt
    12121 ttcaaagaac ttcatagacc tagcggggaa gagttgtata aaatcttaga ggtacaatca
    12181 actacggagg aatagagatg ctcagattag tttactatca atttttacat aataagaaac
    12241 aatggttagg cgtttcacca gtaatttttg tttcgagttt agttatggga ttggctgtta
    12301 atggggtaat taatgttgag aataattcgc aagtatttgt cggacttcca gatcctaaac
    12361 caatttttat gtttccgata gtattcggag gagtaacatt attctttgtg ctctctaaca
    12421 taataaatat gttggttgaa atttttagag atgattacga acttctggag gtgttgggag
    12481 caagtctcct tcaactatca tttcttgtgg ggggacagat ttttatcatt tcctcgatta
    12541 ttagttttat tgcatatcta tgctctatat ttgttacgtc aaattattat tattttttac
    12601 aatacttttt cggggaaaat atattacctg atatccaatt tcaaacgagt gctgttggat
    12661 gtatcattac agtagtgttg atttcatttt tagcctttct aagtggttgc ttttatacgt
    12721 tcaagaagat tagaaatagg aagagttcta aaataaggca tgttctttca atagtaaaaa
    12781 gaatactgct attggctggt tttagtgtta tctggttgct ttctttgcaa caaattttcc
    12841 aagatagcac aattttagcg aaggcccaga taatattcaa tattgtaatc ttagatattg
    12901 tgattattta tcaattatct ccttttatac agtcatgttt tatcaaacta ctttctataa
    12961 ttatatttag aaataatttt atgttcattg cttcgaagtg gaatttacta tatcgtaagc
    13021 cttatataaa atctatcagt gctgcaatta caggagctat attactaatt tctagttttc
    13081 aaatgatttc tcagaatata ctatctcaat ttcaagatga cagtgattta gagctaaaag
    13141 tggcatttat tgtctatgta ggagcaccaa ttttgatagt acttgcaaat attatttcaa
    13201 ttgcattttt gtcatcgcat caagaaagga ttgagattca gcaatttgaa attttaggaa
    13261 cttctaatta ccagatggtt aagattaaag ttggtgaggc tatatttttg acatttgtta
    13321 cttcattaat tgcattttta cttaacatta aaattatggc tttaatatac tactctttag
    13381 aggatgtttt aatagatgat atgaatcttt tggggttaat acttccaaat tttatagtgt
    13441 ctattatttt atttatttta atatttatta ctaaaagttc ctattttatc tttaagaatg
    13501 caaaaattat ttcttaaaaa tttgtaagtt ttcgctatat aaaatagtta aatctatttt
    13561 gtatcattgc ttgcatttta ctggtggaga gaatataatg agggtggata aagtacttaa
    13621 tcccaaaaat ttaaatagga ggagctagct atggcagaag aagtattaaa tcttcaatta
    13681 gtatctgttc aagttgacga aacagatgaa gttgatggaa tgcgatttag tacattcagt
    13741 acaaaccgtt gcggtaactg gagtgctttt agttgggaaa attgttaatt catttaaatt
    13801 gtaaacttta gggattctct gaagttatgg atgtcgttcc aatatgtgta cgttggaatg
    13861 ttagtgctta tatgggggga acagaatcct ctcttgattg aagacaagtt agccattagg
    13921 ctggtttgtc tctttgtcaa ctgtagtggg ttgatataat agtattagtg agtgggataa
    13981 aagtttcatt tagtttattc agtacaaatt taacgggtca agatttattg aactgcaccc
    14041 caatagttag acagaa
//
LOCUS       DAVBEO010000054        13741 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 009
            SAMEA1678075-rid20185393.denovo.054, whole genome shotgun sequence.
ACCESSION   DAVBEO010000054 DAVBEO010000000
VERSION     DAVBEO010000054.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678075
            Sequence Read Archive: ERR226392
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 13741)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13741)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980207.1
            Genome Coverage       :: 150x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:50:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 72 of 147
            Pseudo Genes (incomplete)         :: 72 of 147
            Pseudo Genes (internal stop)      :: 42 of 147
            Pseudo Genes (multiple problems)  :: 32 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13741
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678075-rid20185393.denovo.054"
                     /strain="KS 009"
                     /db_xref="taxon:1313"
     gene            2..1242
                     /locus_tag="VQ543_001752"
     CDS             join(2..341,341..1242)
                     /locus_tag="VQ543_001752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611423.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HET2612433.1"
                     /translation="MVKLIDRYGIEIVKKGKNRHYSSKLKQEMMDKALLEGCSQRSIS
                     LDYALPNQGMLSFWPAQYKKNGYTIVEKTRGRPAKMGRKRKKTWEEMTELERLQEENE
                     RLRTEVAYLKKFKRVRGKGRSPRARKAETVREMVSGGFRLDFLLETARLARSTYYYQL
                     KQLDGVDKDKEIKTEIQGIDNEHKGNYGYRRIHLELRNRGFVVNHKKVQRLMRILGLT
                     ARIRRKRKYSSYQGEIGKKAENLIQRQFEASRPMEKCYTDVTEFAIPNSTQKLYLSPV
                     LDGFNSEIIAYHLSTSPNLEQVKSMLEQAFTEKYYENTILHSDQGWQYQHDSYHRFLE
                     SKGIQASMSRKGNSPDNGMMESFFGILKSEMFYGYEKNFRSLENLEQAIVDYIDYYNN
                     KRIKVKLKGLSSVQYRTKSFG"
     gene            complement(1477..2085)
                     /locus_tag="VQ543_001753"
     CDS             complement(1477..2085)
                     /locus_tag="VQ543_001753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001165927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HET2612434.1"
                     /translation="MQIKFIDKVSNLIMLNLLYVASVVTVIAIGSGESALIATLIKIV
                     RHEESYPYRDFANSFFKDYWKNLGAALISNLPILILLFSLFFLPYIPLPIYIISILRH
                     IGVIYIILHLIATTFLIPLIGRYNNTLKNSLHNSIMLAYKHFFIAVLIRIIEIIPVLL
                     FFILQNQLLVWITLMIFILPSITKYANAFLYNFIFSKYEKLN"
     gene            2251..2421
                     /locus_tag="VQ543_001754"
                     /pseudo
     CDS             2251..2421
                     /locus_tag="VQ543_001754"
                     /inference="COORDINATES: protein motif:HMM:NF013577.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
     gene            2410..3021
                     /locus_tag="VQ543_001755"
     CDS             2410..3021
                     /locus_tag="VQ543_001755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001821036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HET2612435.1"
                     /translation="MTKDILELESQKMSSDTFIDEIKNNYLSIVESTRKLIDGRQIEL
                     AIKLIREANQILMIGVGSSGNAAREFESSLLRIGIISKTVIDTHFQLMHTALLKDNDL
                     IIAFSLSGSTKEVEETLLNAKRKNVKIISITNYSSRNIAKLSDCVLLTSKKESYLEGG
                     SLMAKASQLFIIDVICTRLSLINYEDTICKKEEIASLLSNKVE"
     gene            3738..4424
                     /locus_tag="VQ543_001756"
     CDS             3738..4424
                     /locus_tag="VQ543_001756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000448315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HET2612436.1"
                     /translation="METKKIKNLKGQIIVSCQALEGEPLYTPNGGVMPLLAKAAFQAG
                     AKGIRANSVRDISEIKEEVDLPIIGIIKRDYDGFEPFISATMKEIDELVSEGVDILAL
                     DCTNRSRPGYDNITDFIHDIKVKYPNQLLMAAISTFEEGKVAAESGVDFVGTTLSGYT
                     PYSPKKDNPDFELVERLVKELDVPVIAEGRISTPEQARKMLDLGAYAVVVGGAITRPL
                     EIAKKFIEVV"
     gene            4425..5357
                     /locus_tag="VQ543_001757"
     CDS             4425..5357
                     /locus_tag="VQ543_001757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001071049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HET2612437.1"
                     /translation="MNQEILKKSKIQLTVEHIQKYWILYLMMIPATVLLILFTYGPMY
                     GIIMAFQDFTVFKGYTGSPFVGLKHFQRLFSDPLFYRLFKNTFMVGVLDFLFFFPAPL
                     IFALILNEVRKVRFKSVVQSISYLPHFIPLVVMVGIIFELFGSYGIINSLLSSLGMEP
                     ISFFTKSEWFLPLYIGSGVWKTIGWGSIIYMGALTNIDSTLYEAADMDGANRWHKMWH
                     VTLPSLRPTVVTLFILNAGGIMQVGFEKVFLMSSPATYEVSDVLSTYVYRQGILNSDF
                     SYSAAVGLFNNIVALLFVLLANKIAKKLGEEGIV"
     gene            5368..6297
                     /locus_tag="VQ543_001758"
     CDS             5368..6297
                     /locus_tag="VQ543_001758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000577774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HET2612438.1"
                     /translation="MIFSKNTKKSNRDKETFVDYLFIFILIIITLLMLYPLWWVVMTS
                     LSEPVWLSKNVVKLFPLKIDITAYKFIFGDSKLWQAYGNSVLYAALSTIVSVAVCSMY
                     AYPLTIPEIRGKKFWNTLILIPMFFSGGMIPLYIQVANLGLLNTAWALVLPGAVSTYY
                     IILFRTQFKSIPMELRESARIDGASEFRIFWNLVLPLSKVIFMIIALYCIVGSWNSFT
                     PPLLYLNDDTKMPLSIYLRNLVVTNTTDTAELSLSAGNTYYQQIAAQGGGIGMRIAIK
                     MGTIVVSVIPIMMIYPFIQKHFVKGILLGSVKG"
     gene            6311..7750
                     /locus_tag="VQ543_001759"
     CDS             6311..7750
                     /locus_tag="VQ543_001759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001178946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2612439.1"
                     /translation="MQNLKKYLLLDSGLVVGYTLENAQLKLNKLKKDTENNPLFGEEY
                     FAENPKLWEVRFDNSYPNVIYDKELKLYRCWYQTFVSDEASEETPLAERGEKEYIVKS
                     SRMTALCYAESKDGVKWEKPNLNLVKFKGSKDNNIVLMHAHGAGIMLDEQELDPKKRY
                     KLVSKLEFSPNLHYMVVVFSEDGIHFDEPIPWKKWNPAADSHNFPFRDPKTGKYAVIT
                     RTWANNVRLSAITFSDDFINWSEPKEILRGDGFEDQIYSMPVISYADIYLGFASMYHE
                     GDTLNENYDKVDLELKFSANLEQWDSVCKGDYLIERGGGVYPQNADFDASCIFTAAPI
                     IEDDKIWFYYMGGNGNHTGFRESSLARGYIKKDQFAYYTNKREGIPAKISTVSFQTYD
                     DEIYILADIPENGYIKVAVGTKYGNAYSDFGQEDISLVQVSDGKYKLEFNKKSILDLG
                     NSPVAFKFEIENAKLYGIEGSIQQHYLKY"
     gene            7819..9396
                     /locus_tag="VQ543_001760"
     CDS             7819..9396
                     /locus_tag="VQ543_001760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000239902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HET2612440.1"
                     /translation="MVKLNKVLKGSVAFLSASLLLAACGNNANSKPAEKTADGKTKIS
                     FLSTWQINDVRPPKDETLVGQWLEEQLGIDIDLVTIPGEGVSSKVNSLITSNQLPTVL
                     LTTGDKSDIAGINKLGKQGAFLDLSQHMDKLPNYKKYLEKNNALAQIEDDEKHIYAFT
                     KFFTDENIMYTTPILRKDLLVGSEFEDLSKIKTVDDYTKVLKYLTEKQGSPAFIQRNG
                     YEGFMKRVTPLWNLSHRTYYDYESDSYKHPVEQPQLKQFVEWLKELRKDNVLHPDWAV
                     MKDETWEGLLASNKGSFTVDRMNIIGDNNFDKSFDWQPLVYPEINGKRYLQPKTPYIS
                     DSGWVINANAPKEEIDKALEFFNFLYADENQEKLAIGFEGKTFTRENPNTQAGIKWLI
                     QIYGENAGNDKAELLFKHGNQAFTRVQTKLDIEAQPGTFPKVMYDQVDKIKKDLGGFR
                     PDTPVLSFTTEELDVLTKSEAGLNTFFDENIIKFIEGQRDMSEWDSFINEAKSKDLDK
                     VTKVYNDAYKRVKDRMK"
     gene            9456..10916
                     /locus_tag="VQ543_001761"
     CDS             9456..10916
                     /locus_tag="VQ543_001761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000272432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HET2612441.1"
                     /translation="MYDVVIIGAGSSGALAAIASGRLGLKTCLIEKGSRIGGVPINTL
                     MGSFANLYFDDSGRVNASKIVGELIERIIKKGGTVFNSMEELMNVNDFYQITIPYQPE
                     VYESVLTDMLIESKVDILLNVEVNNIIYDSKNIKSLEILSNQEVKLIDSKVFIDATGN
                     ATIASASGADVYEKNSSYGCLMRVGGVDISKTIEHIEKTKQWNYIEGYNQWLEEVLAN
                     RKYRATGAVLKDPVSYDHAPMLSKDDHFMNDEKWNYIKERWEKFRFIYTLEVSLFRNE
                     LKKAVESGDFNFEIYHDDKSGVTMNGDGISYGSWGQNVALINVAKAFGFNPKYMEDES
                     HANILSRKYNLTFLSFLKKYVPGFENSFILDQGTRATNRSCRHIDNSSMMDEILDFPM
                     YTFKTMYSYQTPKEITYKSIVGGKLNNLFVIGKGAYQSESFRSQISCMLMGISSAAAA
                     KTIIEDKSNTLNINRDLFKSNLDILFTWEFSNWITD"
     gene            10938..11393
                     /locus_tag="VQ543_001762"
     CDS             10938..11393
                     /locus_tag="VQ543_001762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001000318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIT domain-containing protein"
                     /protein_id="HET2612442.1"
                     /translation="MNDTNKNQYFVYEFDTSFVEMSYSQFFEGYCILFSKEPYPSLSD
                     MPMEFRKEFLMEMSILGDAMLEVLNAYRINYDILGNSTPVLHAHLFPRYMWEEEERRK
                     TVVHRYDSSVFSNPEFEFTIEKHGPIIKKLRSAIDRHYREYQQLLDDSN"
     gene            11480..11885
                     /gene="cdd"
                     /locus_tag="VQ543_001763"
                     /pseudo
     CDS             11480..11885
                     /gene="cdd"
                     /locus_tag="VQ543_001763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221146.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
     gene            11898..12347
                     /locus_tag="VQ543_001764"
     CDS             11898..12347
                     /locus_tag="VQ543_001764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HET2612443.1"
                     /translation="MELVEFKNGHVNTVHEHIAITKVKEFLNNHDILKDKGGIHKIST
                     DFFYNIIDMETTTEENRPWESHKEYYDVHYLLNGEETILYNFLSQMELSEYKVDDDWQ
                     QMNGTALFSIKLKKDMLLLLEPNDAHRTGLLVEEPLNIKKVVFKVKI"
     gene            complement(12459..13018)
                     /locus_tag="VQ543_001765"
                     /pseudo
     CDS             complement(12459..13018)
                     /locus_tag="VQ543_001765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            13287..13741
                     /locus_tag="VQ543_001766"
                     /pseudo
     CDS             13287..13741
                     /locus_tag="VQ543_001766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         4865 a         1850 c         2538 g         4488 t
ORIGIN      
        1 catggtgaaa ttaattgacc gttatggcat agaaatcgtt aaaaaaggga agaatcgtca
       61 ctattcttct aaattgaaac aagaaatgat ggataaagcc ttactggaag gttgttcaca
      121 aagaagtatt agtcttgatt atgccctccc aaaccaagga atgctttcat tttggccggc
      181 acaatacaag aaaaacgggt atactattgt tgagaaaaca agagggagac cagctaaaat
      241 gggacgtaaa cggaagaaga cttgggaaga aatgacagaa ctagaacgac tccaggagga
      301 gaatgaacgc ttacggactg aggtggccta cctaaaaaag ttaaaagagt tagaggaaag
      361 ggacgaagcc ctagagcgag aaaggcagag acagttagag aaatggtttc aggaggattt
      421 cgactagatt ttcttcttga aacagcacgt ttagctcgct cgacttacta ttatcagttg
      481 aaacaactgg atggggttga taaagataaa gagattaaaa ccgaaattca gggcattgat
      541 aatgaacata aaggcaacta tggctatcgt cgaatccatt tagaactaag gaatcgtggt
      601 tttgtggtca atcataagaa agttcaacgg ttgatgagaa ttcttggttt aacggctcga
      661 attcgccgta aacggaagta ttcttcctac caaggagaga ttggcaagaa agcagagaat
      721 ctcattcaac gccagttcga agcatcgagg ccaatggaaa agtgctatac agatgtgaca
      781 gagtttgcca ttccaaatag cacacagaaa ctctatttat caccagtttt agatggtttt
      841 aacagtgaaa tcattgctta tcatctttct acttcgccaa acttagaaca agtgaagagt
      901 atgttagaac aggcctttac agagaaatac tatgagaata cgattctcca tagtgaccaa
      961 ggctggcaat accaacacga ttcttatcat cggttcctag agagtaaggg aattcaagca
     1021 tccatgtcac gcaagggcaa cagcccagac aacggcatga tggaatcttt ctttggcatt
     1081 ttaaaatccg aaatgtttta tggctatgag aagaacttta gatctttaga aaaccttgaa
     1141 caagctattg tggactacat tgattactac aacaacaaac gaattaaggt aaaactaaaa
     1201 ggacttagtt ctgtgcagta cagaactaaa tcctttggat aaattatttg tctaattttt
     1261 tggggtcagt acagtattaa ataccatgat cttatgcgtt ttataataaa aaatctgttc
     1321 ttgttttatt tttagaaaat ttactaaaga ctaaaaatat tatgaataat ttaaaaaata
     1381 gtcaggttat atagtttttt gaaattaaaa ttattttatc gttgaaatta gttaaaaatt
     1441 tttataaaat caagatgcaa ggctatgaga tgttctctag tttaattttt catacttcga
     1501 gaatataaag ttatataaaa atgcattagc atattttgtt attgagggaa gtataaaaat
     1561 cattaaagtt atccaaacta gtaattgatt ctgtaatata aagaagagta gaactgggat
     1621 aatttcaata attctaataa gaacggcaat aaaaaaatgt ttataggcta acatgattga
     1681 attgtgtaga gaatttttta aagtgttatt atatctaccg attaaaggaa ttagaaatgt
     1741 tgttgctatt aaatgaagta tgatatatat tactccaata tgtcgtaaga tagaaatgat
     1801 atatataggt aatggtatgt agggtaggaa gaacaaactg aataataaga ttaaaattgg
     1861 taaattagat attaatgctg ctcctaaatt tttccaataa tctttaaaaa aactgtttgc
     1921 gaagtctcta tagggatagg attcctcgtg tcgtacaatt tttattagag ttgctattag
     1981 ggcactttca cctgatccga tagcaataac tgttactact gacgctacat agagtagatt
     2041 taacattata agatttgaaa ctttatcaat aaattttatc tgcatcttta actcctgctg
     2101 tttttatact tataatatca catcatttga gtttcatcaa ctttgaatac attaagaaag
     2161 aatataacta tgaggaaagg aaaaaattat tatgaataaa tccaaaaaat ataaagaaag
     2221 aattcattat gaatacgata atcttactaa atcagagaaa aaattgctga ctatatttta
     2281 gttagagata gtgaaatagt ttatgaaacg tcttcagaaa ttgttagtaa agtaaaagtt
     2341 ggagagggaa ctcttaatcg attttgcaaa aagattggat actctggttt tcaggaacta
     2401 aaattaaaaa tgacgaaaga tatattagag ttagaatctc aaaaaatgag tagtgacaca
     2461 tttattgatg aaataaaaaa taattattta tctattgtgg aaagtacaag aaaattaatt
     2521 gatggtagac aaatagaatt agctataaaa ttaataagag aagcaaacca gattttaatg
     2581 attggtgtgg gttctagtgg aaatgcggct agagaatttg agagtagttt gttaagaatt
     2641 ggaataataa gtaagacggt aattgatacc cattttcaac tcatgcatac tgcgttattg
     2701 aaagataatg atttgataat agcgtttagt ttatctggtt ccacaaaaga agttgaggaa
     2761 actttattaa acgcaaaaag aaaaaatgtt aaaattattt caataacaaa ttattcgtcc
     2821 agaaatatag caaaattatc tgactgcgtt cttttgacat caaaaaaaga atcttattta
     2881 gagggtggta gtttaatggc taaggcttct caactattca taattgatgt aatatgcact
     2941 agactctctt taataaatta tgaagatact atatgtaaaa aagaagagat tgcttctttg
     3001 ctgtcaaata aagtggaata aatcaataat ttttaaattt taataaaaat tttttaaaat
     3061 aaattaaaaa acgatcctaa aagggtcgtt tttttgctaa agttttaaaa ataaacaata
     3121 attaagatta tagtgcgttg aatctatatt aggacataac aattcttaaa tcattgttag
     3181 aaattagttt gaattttcca atcaatttgt tcgattttta catcattgca ttatatcacg
     3241 tgactattaa ccttgttttc tcctaaaatt gattttcttc ttttcttatc ttgtccactc
     3301 gaaacaagta ttgtaagaat ttgattattt ttgaaagtac ttttaatata tttgagatag
     3361 ttaaaaaaga tttgaaacta aattccaaat tagaaaaaga cttgaaatgc taaaaaaaaa
     3421 aagtatactc taattgaaaa cggtaacaaa actaatttag agaatgaaat atagagtatt
     3481 tctctcttaa aagtttttgg tgaaacgaga tgtagaaagg agatttagcc aaagagtcta
     3541 ttagtgctag aataatagat tagaattata gtgtattgaa tctataacag tacgccttaa
     3601 atgctaaaat atttctataa attaatttaa ctttcctgat agggctgttc atatcttatt
     3661 tcaattcact atataaataa aattgtagta gatgttattg aattagtaaa aaaaataaaa
     3721 aaacggaggt tttctgaatg gaaactaaaa aaattaaaaa tttaaaaggt caaataattg
     3781 tttcctgcca agcgttagaa ggagagccac tttatactcc aaatggagga gtgatgccgt
     3841 tattagcaaa agccgccttt caagcaggcg ctaaaggtat tcgtgctaat tctgtccgcg
     3901 atatttcaga aataaaagaa gaagttgact taccaattat aggtatcata aaaagagatt
     3961 acgatggctt tgaacctttt atttcagcaa ctatgaaaga gattgatgaa ttagttagtg
     4021 aaggagtaga cattttagct ttggattgta ctaatcgttc aagaccaggt tatgataata
     4081 ttactgactt tattcatgat attaaagtca agtatccaaa ccaattatta atggctgcta
     4141 tttctacttt tgaagaaggg aaagtagctg ctgaatcggg agtagatttt gtgggtacga
     4201 cattatctgg ttatacacca tatagcccta aaaaagataa tcctgatttt gagttagttg
     4261 aaagattggt aaaagagctt gacgtaccag ttattgctga aggaagaata agtactccgg
     4321 aacaagctag aaaaatgtta gatttaggtg cttacgcagt ggttgttgga ggagctatca
     4381 ctcgtccttt ggaaatagcg aagaagttta ttgaggtagt ttagatgaat caagaaatat
     4441 taaaaaagag taagattcaa ttgacagttg aacatattca aaaatattgg attttatatt
     4501 taatgatgat tccagcaact gttctactaa ttttatttac gtatggacca atgtacggca
     4561 ttattatggc ctttcaagac tttactgtct tcaagggata tactggaagt ccatttgtcg
     4621 gtttaaaaca ttttcaaaga ttgttctcag atcctttgtt ttatagattg ttcaagaata
     4681 cgttcatggt aggggtttta gattttttat tctttttccc agctccgctt atttttgcac
     4741 tcatattaaa cgaagtcaga aaagtaagat ttaagagtgt agttcaatct attagttatc
     4801 ttcctcattt tattccccta gtggttatgg ttggtattat ttttgaacta tttggttcat
     4861 atggtattat taacagttta ctttcatcac ttggaatgga gccaataagt ttctttacaa
     4921 aatctgaatg gttcttgcct ctctacattg gttcaggagt atggaaaaca ataggttggg
     4981 gttctatcat ttatatggga gcattaacca atatagattc aactttatat gaagcagcag
     5041 atatggacgg ggctaataga tggcacaaaa tgtggcatgt aactctacca agtttaagac
     5101 ctacagtagt tactttgttt atactaaatg ctggtggtat catgcaagta ggatttgaaa
     5161 aggtattctt gatgtctagt cctgcaacat atgaagtatc tgatgtatta tctacttatg
     5221 tttatagaca aggtatttta aattctgatt tcagttactc agctgcagta ggattattta
     5281 ataacatagt agctttgtta tttgttttat tagctaataa gattgctaaa aaacttggcg
     5341 aagaaggaat tgtataaggg gggtaaaatg attttttcaa aaaatacaaa aaagagtaat
     5401 agagacaaag aaaccttcgt tgattatctc tttatattca ttttaataat aataacctta
     5461 cttatgttgt atccattatg gtgggtagtg atgacgtcac tttcagaacc agtttggcta
     5521 tctaaaaacg ttgttaaatt atttccctta aaaatagata ttactgcata taagtttatt
     5581 tttggggatt ctaaactatg gcaagcatat ggtaatagtg tattgtatgc tgcactatct
     5641 acaattgtta gtgttgcggt atgtagtatg tatgcctatc cacttacaat tcctgaaatt
     5701 aggggtaaaa aattctggaa tactcttatt ttgattccaa tgttctttag tggaggaatg
     5761 atcccgcttt atatacaagt tgcaaacctc ggtttattga atactgcttg ggctcttgtt
     5821 ttacctggtg ctgtttctac atattatata attttgttta gaacacagtt taaatcaatc
     5881 ccaatggagc ttcgtgagtc tgctagaatt gatggggcaa gtgaatttag aattttttgg
     5941 aatttagtat taccattatc aaaagttatt ttcatgatta tagcacttta ttgcatagtt
     6001 ggttcatgga atagttttac tcctccatta ctttatttga atgacgacac taagatgcct
     6061 ttatctattt atttgagaaa tttagtcgtt acaaatacaa ctgatactgc tgaattatca
     6121 ctttctgcag gtaatacata ttaccaacaa attgctgctc aaggtggagg tattggtatg
     6181 cgtattgcta ttaagatggg tactattgtt gttagtgtta ttccaattat gatgatttat
     6241 ccatttattc agaaacattt tgttaaggga atcctgctag gttctgtgaa aggttaataa
     6301 ggtaattatt ttgcaaaatt taaaaaaata tcttttatta gatagcggtt tagtagttgg
     6361 gtatacatta gaaaatgctc aattaaaatt aaataagcta aaaaaagata ctgaaaacaa
     6421 tccactattt ggtgaagagt attttgccga aaatcctaaa ttatgggaag ttcgttttga
     6481 taattcatat ccaaacgtta tctatgataa agaattgaaa ttatatagat gttggtatca
     6541 aacatttgtt agtgatgaag caagcgaaga gactccttta gcagaacgtg gagagaagga
     6601 atacattgtc aagtcatcta gaatgacagc actttgctat gctgaaagta aagatggagt
     6661 aaaatgggaa aaaccaaatc tcaatctagt aaaatttaaa ggttcaaaag ataataatat
     6721 tgttctgatg catgcacacg gtgcaggtat catgctagat gaacaggagt tggatcctaa
     6781 gaaacgatat aaattagttt caaaattaga attttctccg aatcttcatt acatggttgt
     6841 tgttttttca gaagacggta ttcattttga cgaacctatt ccatggaaaa aatggaatcc
     6901 tgcagcagat agtcataatt ttccatttag agatccaaaa actggtaaat acgctgttat
     6961 tacaagaacc tgggcaaata acgtacgtct aagtgcaatt actttcagtg atgattttat
     7021 taattggtca gaacctaaag aaatccttag gggagatgga tttgaagatc aaatttattc
     7081 tatgccagta atttcatacg cggatatcta tttaggtttt gcttcaatgt accatgaagg
     7141 cgacacttta aatgaaaact atgataaagt agacttagaa ttgaaattct ctgctaattt
     7201 ggaacaatgg gatagtgtat gtaagggcga ctatctcatt gaaaggggag gtggagtata
     7261 cccgcagaat gctgattttg atgctagttg tattttcacg gctgctccaa taattgaaga
     7321 tgataagatt tggttctact atatgggtgg aaatggtaat cacactggct tccgagaaag
     7381 ttcattagct agaggatata ttaagaaaga ccaatttgct tattatacta ataagagaga
     7441 aggaattcca gctaaaatat ctacagttag cttccaaact tacgatgatg aaatttatat
     7501 cttagctgat attcctgaaa atggttatat taaagttgcg gtaggtacta aatacggtaa
     7561 tgcttattca gatttcggtc aggaagatat ctctcttgtt caagtttccg atggtaagta
     7621 taagttggaa tttaataaaa aatctatctt agatttaggt aattctccag ttgcgttcaa
     7681 atttgaaatc gagaatgcaa aattgtatgg tattgaaggt agtattcagc aacactatct
     7741 caaatattaa ccagaataat tcgttaacaa ataatctcta tattagtgga gatagatata
     7801 taaaatggag gtcttattat ggtaaagctt aataaggtat taaaagggag tgttgcattc
     7861 ctgagtgcaa gtttattgct agcagcttgt ggcaataacg ctaattcaaa gcccgctgaa
     7921 aaaacagctg atggtaaaac gaaaatttcg tttctatcta catggcaaat taatgatgtt
     7981 cgtccgccta aagatgaaac acttgttggt caatggttag aagaacagct aggtattgat
     8041 attgatcttg taactattcc tggcgaggga gtaagttcta aagtaaattc tcttattact
     8101 agtaaccagt taccgactgt tttgttgaca acaggagata agagtgatat cgctggtatc
     8161 aacaaacttg gtaaacaggg tgcattctta gatttgtcac aacacatgga caaactacca
     8221 aactataaga agtaccttga aaaaaataat gcattagctc aaatagaaga tgatgaaaaa
     8281 catatttatg ctttcacaaa attctttact gatgagaata tcatgtatac tacaccaatt
     8341 ctgagaaaag acttacttgt tggttcagaa tttgaagatc tttcaaaaat taaaactgtt
     8401 gatgactata caaaagtttt gaaatatttg actgaaaaac aaggttctcc agcatttatt
     8461 caacgtaatg gctatgaagg cttcatgaag cgagttacac cattgtggaa tttaagccat
     8521 cgtacatact atgactatga atcagattca tataaacatc cagttgaaca acctcaattg
     8581 aaacaattcg ttgaatggtt gaaagaatta cgtaaagata acgtacttca ccctgactgg
     8641 gcagttatga aagatgaaac ttgggaaggt ctattggctt ctaacaaggg ttcattcact
     8701 gttgaccgta tgaatatcat tggagataat aactttgata aatcatttga ttggcagcca
     8761 cttgtttatc cagaaattaa tggaaaacgt tatttgcaac cgaaaacacc gtacatttct
     8821 gattcaggtt gggtaatcaa tgccaatgca ccaaaagaag aaattgataa agcgttagaa
     8881 ttctttaatt tcttatacgc tgatgaaaat caagaaaaac ttgctattgg atttgaaggt
     8941 aaaacattta cacgtgaaaa ccctaatact caagcaggta ttaaatggtt gattcaaatt
     9001 tacggtgaaa atgctggaaa tgataaagca gaactgctgt ttaaacatgg taaccaagca
     9061 tttactcgcg ttcaaactaa attagatatt gaggcacagc caggaacatt ccctaaagtt
     9121 atgtatgatc aagtagataa aattaagaaa gatttaggtg gttttagacc agatactccg
     9181 gttctttcct ttacaactga agaattagat gttttaacta aatctgaagc aggattaaat
     9241 actttctttg atgaaaatat tattaaattc attgaaggac aaagagatat gagtgagtgg
     9301 gattcattta tcaatgaagc taaatctaaa gacttggata aagttacaaa agtatataat
     9361 gatgcctaca aacgtgtcaa agatagaatg aaatagacta aatggtagct ctctggtttt
     9421 tcagagagct actactgcct gagggggagt aagctttgta tgatgtagta attataggtg
     9481 caggaagttc gggcgcattg gctgcaattg cttcggggcg tctagggtta aaaacttgtc
     9541 taatagagaa gggaagtaga attggtggag ttcctattaa tacactaatg gggtcatttg
     9601 ctaatctata ttttgatgat tctggtagag taaatgcaag taaaattgtt ggggaattaa
     9661 tagaacgtat tatcaaaaaa ggtggtactg tctttaactc tatggaagaa ttgatgaatg
     9721 taaatgattt ttatcagatt acaattccct atcaaccaga agtttatgaa tcggttttaa
     9781 ctgatatgtt gattgagtct aaagttgata ttttactaaa tgttgaagtt aataatatta
     9841 tttatgatag taaaaatatt aaaagtcttg aaattttaag taatcaggaa gttaaattga
     9901 ttgattctaa agtttttatt gatgctacag ggaatgcaac aattgcttct gctagtggag
     9961 ctgatgttta tgaaaaaaat tcttcttacg gttgtttaat gagagttgga ggagttgata
    10021 tctcaaagac tatagaacat attgaaaaaa caaagcagtg gaactatata gaaggatata
    10081 atcagtggtt agaagaagta ttagcaaatc gaaagtacag agccactgga gcagttttaa
    10141 aagatccagt ttcttatgat catgccccta tgctttcaaa agacgaccat tttatgaatg
    10201 atgaaaaatg gaattacatt aaagaaagat gggaaaaatt tagatttatt tacactttag
    10261 aagtatcact atttaggaat gaattaaaaa aagctgtaga atctggggat tttaattttg
    10321 aaatttatca tgatgataaa tctggagtca ctatgaatgg cgacggtata agctatggtt
    10381 catggggtca aaatgtagca ttaattaatg ttgcaaaagc atttggattc aatcccaaat
    10441 atatggaaga tgaatcacat gctaatattc tttctagaaa atataattta acatttttat
    10501 cttttcttaa aaaatatgta ccaggttttg aaaattcttt tatccttgat cagggaacta
    10561 gagctactaa cagatcatgt aggcacattg ataattcatc tatgatggac gaaattcttg
    10621 attttccaat gtatacattt aagactatgt atagctatca aactcctaaa gaaataacgt
    10681 acaaatcaat tgtaggtgga aaattgaata atttgtttgt aataggtaaa ggtgcttacc
    10741 aatccgaaag ttttagatca caaattagtt gtatgttaat ggggatatca tcagcagcag
    10801 cggcaaaaac tattattgaa gataaaagca atactctaaa cattaataga gatttgttta
    10861 aatcgaactt agatatatta tttacatggg agttttctaa ttggattact gattaacaaa
    10921 taataaggga atattaaatg aatgatacta ataaaaatca atactttgtt tatgaatttg
    10981 atactagctt tgtagaaatg tcttattctc agttttttga aggatattgt attctttttt
    11041 caaaagaacc ctatccttct ttatctgata tgccaatgga atttagaaaa gaatttttaa
    11101 tggaaatgag tatattaggt gatgcgatgc ttgaagtgtt aaatgcctat agaattaatt
    11161 atgatatctt aggaaattca acacctgtac ttcatgctca tttatttccg agatacatgt
    11221 gggaagagga agagagaaga aaaactgtag ttcatagata tgattcttca gtttttagca
    11281 atcctgagtt tgaatttact atagaaaagc atggaccaat tattaaaaaa ctgaggtctg
    11341 ctattgatag acattataga gagtatcaac aattattaga tgattcaaac tgaactccac
    11401 attttcgatt agatttaata ccttgtatat tacaactagg ttgtggatga tataattttt
    11461 tgaaaaatat attttaggaa tgacttataa agcaattata tcagaggcta ttaaatcaat
    11521 ggccaaagct tatgctcctt attctgattt taaggttgga gctgcgttag taactgaaga
    11581 taaaaaattt tttctggatg taatatagaa aatgctgctt tttctcctac ttgctgtgca
    11641 gaacgagtat ctttttataa agctgtattt aaaggagaac gttcgttttc aagaacatgt
    11701 attgtaggtg gaaaaaatgg tatcttatca tcttttatag caccttgcgg agtgtgtcgc
    11761 caggtaatga tagaatttgt aatcctgatt catttgaagt tatattggct agtgatgttg
    11821 atacttataa agtatataaa cttaaagaac tactaccagt tagttttaat caagaaaatt
    11881 tataacagga gggaactatg gaattagttg aatttaaaaa tggacatgtt aatacggttc
    11941 atgagcatat cgcaataacg aaagtaaaag agtttctaaa taatcatgat atattaaaag
    12001 ataaaggtgg catacataaa atttctactg atttctttta caatataatt gatatggaaa
    12061 ctacaactga agagaataga ccgtgggaaa gtcataagga atattatgat gtccattatc
    12121 tgttaaatgg agaagaaaca attttatata acttcttgtc tcaaatggaa ttgtctgaat
    12181 ataaagtaga tgatgattgg caacaaatga atgggacagc tttatttagt attaaattaa
    12241 agaaagatat gttacttttg ttggaaccaa acgatgcaca tagaacaggc ctattggttg
    12301 aagaaccact taatattaag aaagttgttt ttaaggtaaa aatttaactg aaagtacttt
    12361 cggggattaa gaattttaaa atatttaaga aattgtattc taaagttcta aaattataga
    12421 tatttaattt aaagcttgtt aaaatagaat agtaacactc atctgctttc aaaaagcatt
    12481 ctattccatc tccgattaac gatggacttt atcacctcct tctccagtcc ttgtatgaca
    12541 tcttggagtt gattcatgac atcttccaaa gttcgaaagg ctttattctt aaatccacgt
    12601 ttatgaatct ctttccacac ttgttcgatg ggttcatctc tggtgtgtat ggaggaataa
    12661 atgcaaaacc aatattagtc ggagtcttta aggtacttga tttatgccat atagcattgt
    12721 ccataacgag taaaagataa tcatctggat aagcttgtga aagctcttct aaaaaggcgt
    12781 tcatccactc agtattacat ccaccagcta ttaagaaaaa tgattcgcct gtatgggcat
    12841 caacagctcc ataacaatag tgaaattctc gtatatagtg actatggaca tgtggaccta
    12901 ctcctattgg agaccaacaa gatcccagtt tactgattct accgaagcca gcctcatctt
    12961 ggtacatcaa gcgaacctta tgaaaacgtc tactggtttt aaagcgcttt cttttcttca
    13021 gttgatttca tatcactatt gtataatgct ttttgatttt agtctagtat aaatagcgag
    13081 aaatatctat cctatcttct agaatgtctt ccaaacgagg aaactctcgt aaacaaagag
    13141 gttttagagg cctatttacc gtggactaaa gttgcacaag aaaagtgcaa ataagaaatc
    13201 tccagattag gaactatccg tgagttctct agtctggaga tttttcaata gacttcctgc
    13261 gaaacaaaat atggtataat agttctatga attatgaagc aagtaaacaa ctaaccgatg
    13321 cacgatttaa gcgtcttgtt ggtgttcaac gcacgacttt tgaagagatg ttagctgtat
    13381 taaaaacagc ttatcaactt aaacacgcaa aaggtggacg aaaacctaaa ttaagcctag
    13441 aagaccttct tatggccact cttcaatatg tgcgagaata tcgaacttat gaagaaattg
    13501 cggctgatct tggtattcac gaaagcaact tactccgtcg gagccaatgg gttgaagtaa
    13561 ctcttgttca aaggtggtgt tgcgatttca agaactcctc tcagttctga ggacacggta
    13621 atgattgatg cgacggaagt aaaaatcaat cgacctaaaa aaagaattag cgaattattc
    13681 tggtaaaaag aaatttcacg ctatgaagac tcaagcgatt gtcacaagtc aagggagaat
    13741 t
//
LOCUS       DAVBEO010000055        13451 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 009
            SAMEA1678075-rid20185393.denovo.055, whole genome shotgun sequence.
ACCESSION   DAVBEO010000055 DAVBEO010000000
VERSION     DAVBEO010000055.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678075
            Sequence Read Archive: ERR226392
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 13451)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13451)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980207.1
            Genome Coverage       :: 150x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:50:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 72 of 147
            Pseudo Genes (incomplete)         :: 72 of 147
            Pseudo Genes (internal stop)      :: 42 of 147
            Pseudo Genes (multiple problems)  :: 32 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13451
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678075-rid20185393.denovo.055"
                     /strain="KS 009"
                     /db_xref="taxon:1313"
     gene            complement(<1..1307)
                     /locus_tag="VQ543_001767"
     CDS             complement(<1..1307)
                     /locus_tag="VQ543_001767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory Sec-dependent serine-rich glycoprotein
                     adhesin"
                     /protein_id="HET2612444.1"
                     /translation="MFKVMRGGVDTTQVMTETVEDKVSHSITGLDILKGIVAAGTVIS
                     GTVATQTKVFTNESAVLEKTVEKTDALATNDTVVLGTISTSNSASSTSLSASESASTS
                     ASESASTSASTSASTSASESASTSASTSISASSTVVGSQTAAATEATAKKVEEDRKKP
                     ASDYAASVTNVNLQSYAKRRKRSVDSIEQLLASIKAAVFSGNTIVNGAPAINASLNIA
                     KSETKVYTGTGLDSVYHVPIYYKLTVTNDGSKLTFTYTVTYVDPTTRALGNLSKMGHG
                     YSIYNTGTSIQTMLTLGSDLGTPSDVKNYITDKDGVLVRSYNTSTMTTWGSGYTWGNG
                     AQMNGFFAKQGYGLTSSWTVPITGTDTSFTFTPYAAKTDNIRTNYFKGRGKVVESSTT
                     SQSLSQSKSLSVSASQSASASASTSASESASTSASASASTSAS"
     gene            complement(1305..1418)
                     /locus_tag="VQ543_001768"
                     /pseudo
     CDS             complement(1305..1418)
                     /locus_tag="VQ543_001768"
                     /inference="COORDINATES: protein motif:HMM:TIGR03715.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="KxYKxGKxW signal peptide domain-containing
                     protein"
     gene            complement(1656..2117)
                     /locus_tag="VQ543_001769"
     CDS             complement(1656..2117)
                     /locus_tag="VQ543_001769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000514209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET2612445.1"
                     /translation="MGKERRKQGNLERKKRVVKKRKIPLEELKAFVEAHPDAFLREIA
                     ARFDCALPSVWAVLKQIKVILKKTTSFREQKPEKVSEFLDILDNLKDLPVLYIDETGI
                     NRYLYRPYAGAPRGEKVYDKISGRRFERTNEVEQKLNGSFLIRYIDSQIRE"
     gene            complement(2084..2227)
                     /locus_tag="VQ543_001770"
     CDS             complement(2084..2227)
                     /locus_tag="VQ543_001770"
                     /inference="COORDINATES: protein motif:HMM:NF013842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HET2612446.1"
                     /translation="MAYSTDFKQGALDSIKEGHSHVEAAKFFGVGVRTLFTWEKKDVN
                     KGT"
     gene            2496..2876
                     /locus_tag="VQ543_001771"
     CDS             2496..2876
                     /locus_tag="VQ543_001771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HET2612447.1"
                     /translation="MTYLEKWFDFNRRQKEIESLLEETIAQQSEQSLTLKEFYLLYYL
                     DLAEEKSLRQIDLPDKLHLSPSAVSRMVARLEAKNCGLLSRMCCHQDRRSSFICLTND
                     GQKTLASLQKTVEESLEAGLDFLI"
     gene            2975..3196
                     /locus_tag="VQ543_001772"
     CDS             2975..3196
                     /locus_tag="VQ543_001772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4649 family protein"
                     /protein_id="HET2612448.1"
                     /translation="MIEITYIDASKNERTVTFESYEDFERSQQACLIGVADYYPVQKL
                     TYKGHNLDYHGTYGDIFFYLMKQDLSQYN"
     gene            3213..3527
                     /gene="trxA"
                     /locus_tag="VQ543_001773"
     CDS             3213..3527
                     /gene="trxA"
                     /locus_tag="VQ543_001773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003004519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HET2612449.1"
                     /translation="MAKAITDATFEQETKDGLVLVDFWATWCGPCRMQGPILDKLSEE
                     LSEDVLKIVKMDVDENPNTARAFGIMSIPTLLFKKDGQVVKQVAGVHTAEQIKAIIAE
                     LS"
     gene            3834..4367
                     /gene="queF"
                     /locus_tag="VQ543_001774"
     CDS             3834..4367
                     /gene="queF"
                     /locus_tag="VQ543_001774"
                     /EC_number="1.7.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent 7-cyano-7-deazaguanine reductase
                     QueF"
                     /protein_id="HET2612450.1"
                     /translation="MKHQSALVVFSGGQDSTTCLFWTMQHYETVEAVTFAYGQHHHLE
                     IQITREIAKEQGIRHHILDMSLLGQITAQPDFATIHISYIPDKLCVESKSLKLYLFSY
                     RNHGDFHENCINTIGKDLVNLLDPRYLEVWGKFTPRGGISIDPYYNYGKQGTKYEGLA
                     EQRLFQHDLYPEKIDNR"
     gene            complement(4621..5289)
                     /locus_tag="VQ543_001775"
     CDS             complement(4621..5289)
                     /locus_tag="VQ543_001775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin"
                     /protein_id="HET2612451.1"
                     /translation="MKKFVAELIGTFMLVFVGTGAVVFGNGLDGLGHLGIAFAFGLAI
                     VVAAYSIGTVSGAHLNPAVSIAMFVNKRLSSSELVNYILGQVVGAFIASGAVFFLLSN
                     SGMSTASLGENALANGVTVFGGFLFEVIATFLFVLVIMTVTSESKGNGAIAGLVIGLS
                     LMAMILVGLKITGLSVNPARSLAPAVLVGGAALQQVWIFILAPIAGGVLAALVAKNFL
                     GTEE"
     gene            complement(5400..5954)
                     /locus_tag="VQ543_001776"
     CDS             complement(5400..5954)
                     /locus_tag="VQ543_001776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2785 domain-containing protein"
                     /protein_id="HET2612452.1"
                     /translation="MYQDLLRKIAEEKPNYNQEEIQWLFDHLGNPSPEIRNVLLNQGL
                     HYLSKEKDTRGFSSQYGWVHAFAHGADLLTEVVCHPGFPKNRVHEVFEILGQLFKRMS
                     IRFTDDEDWRLARVIYEPILQGKLAQEQVASWIKTVDFPIEEREDFYKFSNFRSCLVE
                     VYVQLDQRNSLQDELKEAIQSFQY"
     gene            complement(6200..7996)
                     /gene="pepF"
                     /locus_tag="VQ543_001777"
     CDS             complement(6200..7996)
                     /gene="pepF"
                     /locus_tag="VQ543_001777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000435555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HET2612453.1"
                     /translation="MEQKHRSEFPEKELWDLTALYQDREDFLRAIEKAREDINQFSRD
                     YKGNLHTFEDFEKAFAELEQIYIQMSHIGNYGFMPQTTDYSNDEFANIAQAGMEFETD
                     ASVALTFFDDALVAADEEVLDRLGKLPHLTAAIRQAKIKKAHYLGADVEKALTNLGEV
                     FYSPQDIYTKMRAGDFEMADFEAHGKTYKNSFVTYENFYQNHEDAEVREKSFRSFSEG
                     LRKHQNTAAAAYLAQVKSEKLLADMKGYDSVFDYLLAEQEVDRVMFDRQIDLIMKDFA
                     PVAQRYLKHVAKVNGLEKMTFADWKLDLDSALNPEVTIDDAYDLVMKSVEPLGQEYCQ
                     EVARYQEERWVDFAANSGKDSGGYAADPYRVHPYVLMSWTGRLSDVYTLIHEIGHSGQ
                     FIFSDNHQSYFNAHMSTYYVEAPSTFNELLLSDYLENQSNDPRQKRFALAHRLTDTYF
                     HNFITHLLEAAFQRKVYTLIEEGETFGASKLNSIMKEVLTDFWGDAIEIDDDATLTWM
                     RQAHYYMGLYSYTYSAGLVISTAGYLHLKHSETGAEDWLNLLKSGGSKTPLESAMIIG
                     ADISTDKPLRDTIQFLSDTVDQIISYSAELGE"
     gene            complement(8007..8750)
                     /locus_tag="VQ543_001778"
     CDS             complement(8007..8750)
                     /locus_tag="VQ543_001778"
                     /EC_number="2.1.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001188214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (uracil(1498)-N(3))-methyltransferase"
                     /protein_id="HET2612454.1"
                     /translation="MQQYFVKGSAVSPVTIEDRETSKHMFQVMRLKEEDEVTLVFDDG
                     IKRLARVLDMENRQFELVQELNDNVELPVQVTIASGFPKGDKLEFITQKVTELGASQI
                     WAFPADWSVAKWDGKKLGKKVEKLEKIALGAAEQSKRNVVPSIHLFENKADFLAQLDQ
                     FDRILVAYEEAAKEGEAAALIKAVTGLEKGAKLLFIFGPEGGLSPAEIENFEAKGAVL
                     AGLGPRILRAETAPLYALSALSVLVELEK"
     gene            complement(8752..9702)
                     /locus_tag="VQ543_001779"
     CDS             complement(8752..9702)
                     /locus_tag="VQ543_001779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000451122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11 methyltransferase"
                     /protein_id="HET2612455.1"
                     /translation="METWQELKVTVKREGEELVSNLLIELGAQGVAIEDSMDYMGNVD
                     RFGEIFPEVEQQEEIVVTAYYPDTVDMTVVEADLQARLAELTDFMDLGELKIGTTALA
                     EEDWADNWKKYYEPARITHDLTIVPSWTDYEATAGEKIIKLDPGMAFGTGTHPTTKMS
                     LFALEQVLRGGETVLDVGTGSGVLSIASSLLGAKEIFAYDLDDVAVRVAQENIELNTG
                     MENIHVAAGDLLKGVEIEADVIVANILADILIHLTEDAYRLVKDEGYLIMSGIIKDKW
                     DMVRQSAESAGFFLETHMIQGEWNACVFKKTKDISGVIGG"
     gene            complement(9840..10268)
                     /locus_tag="VQ543_001780"
     CDS             complement(9840..10268)
                     /locus_tag="VQ543_001780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HET2612456.1"
                     /translation="MELEISDFQGCKIALFCGDKLLTILRDDKDDIPCPNMWELPGGG
                     REGDESPFECARREVYEELGIHLDEDCLLWSKIYPSVIFKGKKSVFMVGQLRQEQFDN
                     IIFGDEGQGYQLMNVEEFLSSSQVVPQLQERLKDYLKVSD"
     gene            complement(10249..11337)
                     /locus_tag="VQ543_001781"
     CDS             complement(10249..11337)
                     /locus_tag="VQ543_001781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000719715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-2 protease family protein"
                     /protein_id="HET2612457.1"
                     /translation="MKKIGTYLVYVLAVVFIMLAFACGTIAFAELGYSAVLAFTFGYA
                     FALLSMYLIFILHELGHAFCGYLTGYRLVAFGLGHFILTKKSGRFHLSRTAILKNVGA
                     QYIGLKEDESDQRIILMLSGGLMVHLGLILLAIVFGFLTRSWYFAGTWIFLNLSFFLN
                     NILPVDITDGAKIWELLQHPENTKYAYLVLRHSAQTLLAPQEYDLKDFVQAVPEDARG
                     SFADGVLGMQGEVSILEGKEEVAKQQFQALLERTTTPMMQTVAQLSLLHIALLEGDFE
                     QAEQYASIRQVKSFLSLKLSNLQVIQAWYQLKVKKDVDRTRKALKIARQKMDSSRMLR
                     DEKRYYENLLAELEKEMLEGTEDGTRNF"
     gene            complement(11356..11826)
                     /locus_tag="VQ543_001782"
     CDS             complement(11356..11826)
                     /locus_tag="VQ543_001782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000257105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3013 family protein"
                     /protein_id="HET2612458.1"
                     /translation="MATYGFLDVLEEELDKNFPFDFEISWDKRNHAVEVSFLLEAQNA
                     AGVEMVDEDGEVSSDDILFEEAVLFYNPAKSTVNEEDYLTVIPYLPKKGFSREFLAYF
                     VLFLKDTAEVGLDVLMDFLEDPEAEEFVMEWNQEVFEEGKVGLEEGEFYPYPRY"
     gene            complement(12117..12569)
                     /locus_tag="VQ543_001783"
     CDS             complement(12117..12569)
                     /locus_tag="VQ543_001783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000961815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicB family
                     antitoxin"
                     /protein_id="HET2612459.1"
                     /translation="MLVTYPALFYYDDTDGTEATYFVHFPDFEYSATQGEGISEALAM
                     GSEWLGITVADLIESDGELPQPSDINSLSLIDNDPFKDDEDFVSTYDLDKSFISMVSV
                     DVSEYLGSQEPIKKTLTIPKWADKLGREMGLNFSQTLTDAIADKKVQA"
     gene            complement(12606..12785)
                     /locus_tag="VQ543_001784"
     CDS             complement(12606..12785)
                     /locus_tag="VQ543_001784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicA family
                     toxin"
                     /protein_id="HET2612460.1"
                     /translation="MPMTQKEMVKLFTAHGWIKTRGGKGSHIKIEKQGERPITILHGE
                     LNKYTERGIGKQAGL"
     gene            complement(12922..13101)
                     /locus_tag="VQ543_001785"
     CDS             complement(12922..13101)
                     /locus_tag="VQ543_001785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2612461.1"
                     /translation="MNLIFEEYQFVKIGDKKYRVRSGPMIHSTPPQSVLDRDTFTIDY
                     TDDELLDKEAVFTTH"
     gene            complement(13266..>13451)
                     /locus_tag="VQ543_001786"
     CDS             complement(13266..>13451)
                     /locus_tag="VQ543_001786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000818079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2612462.1"
                     /translation="IFTKQIRHWILSDQVISGKRKLFFREDTPKEILDLYENIKSKLD
                     FAYQEVHSNNGLKKYEK"
BASE COUNT         4008 a         3061 c         2435 g         3947 t
ORIGIN      
        1 tctgatgcac ttgtacttgc tgaggctgat gcgctggttg aggccgattc agaagctgag
       61 gtgcttgctg aggctgaggc gctttgacta gcacttactg agagtgactt agactgtgaa
      121 agtgactgac tggtcgtgct agattcaact acctttcctc tacccttgaa gtagttagtt
      181 ctaatgttat ctgttttagc agcgtaaggg gtaaatgtaa aggatgtatc cgttccagta
      241 attggtacag tccaagatga tgttaatcca tatccttgct tagcaaagaa accattcatt
      301 tgggcaccat ttccccaagt atacccacta ccccacgtcg tcattgtaga tgtattatag
      361 gatcgaacca gtacaccatc tttgtcagta atgtagttct ttacatctga aggggtacca
      421 agatcactgc caagggttaa cattgtttgt attgaagtac ctgtattata gatagaatac
      481 ccatgaccca tctttgaaag attaccaaga gcccttgtgg taggatctac atacgtaacc
      541 gtataggtaa aggtcagttt tgaaccatca tttgtcactg tcaatttata gtaaattgga
      601 acatgatata ccgaatctaa acctgtacct gtataaactt ttgtctcact tttagcaatg
      661 tttagacttg cattaattgc aggggcgcca tttacaatcg tattgccaga aaaaacagca
      721 gcttttatag aagccagcaa ttgctcgatg gaatccactg aacgcttgcg tcgcttagca
      781 taagattgga gattgacatt tgtaactgat gctgcataat cactagctgg tttcttacga
      841 tcttcttcga ccttcttagc agttgcttct gtagcggcag ctgtttgtga tcctaccaca
      901 gtagatgatg cagagatact tgtcgaagcc gatgtacttg ctgattctga tgcacttgta
      961 ctcgctgagg tcgaagcgct ggttgaggct gactcagatg cagatgtact tgccgactct
     1021 gaagctgaca aactagttga actcgctgaa ttacttgtag atatcgtacc tagaactact
     1081 gtatcatttg ttgccaaagc atccgttttc tctacagttt tttcaagtac tgccgactca
     1141 tttgtaaata ccttcgtttg agttgcaacg gttccactta tgacagttcc cgcagcaact
     1201 attcccttga ggatatcaag cccagtaatt gaatgactta ctttatcttc taccgtttcg
     1261 gtcatgacct gagtagtatc aacaccacca cgcatgacct taaacaagcc aaaaagagaa
     1321 gtcgaggccc gtagccaatg cttccctgat ttgattaatt tgaaccgagt tactcggtct
     1381 gtttctctat attcaccctt ctgacgtcta aaaaatattt tgaaatttcc tttcgagtat
     1441 tattttcatg tatggatata aataaattac catactataa ttatagaata gggaacccaa
     1501 aatagcaaga aacttgaggt atttttgcta aaaaaaaaaa gcattttact attttatata
     1561 tatattataa gataagtttt ttataaagac acgcaaatga gtataaatca gctaattttt
     1621 ggtttatatt cctattttta tgcataatta ttctttcatt ctctaatttg tgaatcaata
     1681 tatctgatta gaaaactacc attgagtttt tgctccacct cattagtccg ctcaaaacgc
     1741 cgtccgctaa tcttgtcata gactttctcc cctctaggag cccctgcata aggacgatag
     1801 aggtagcggt tgattcccgt ttcgtcaata tataggactg gtaaatcttt taggttatcc
     1861 aaaatatcaa gaaactcaga aactttctca ggcttttgtt ccctaaaact ggtcgtcttt
     1921 tttaaaatga ccttaatctg ctttaaaact gcccatacgg agggcaaagc acaatcaaaa
     1981 cgggccgcaa tttcccgtaa aaaagcgtct ggatgagcct ctacaaaggc tttcaattct
     2041 tctaaaggga tcttacgctt tttgacgact cgctttttcc gctctaagtt cccttgttta
     2101 cgtctttctt ttcccacgtg aagagagttc tgacgccaac accaaaaaac ttggctgcct
     2161 cgacatgact gtgcccctct ttgatggaat ctaatgctcc ttgtttaaaa tcagtactat
     2221 atgccatagc tttattagac catgcttatt ttaaactaag caactataga tagagaaatg
     2281 aaataaaatc taaattcgaa tgtgataagg agttagaaat tgaaacaata ggattccccc
     2341 attattcaca caaaaataaa accactaaaa aacagagctt gccagcattc ttgaaaagta
     2401 gtataattat tgcatgcgca atcatcttgt gacgcagaga ctgcccgtta atggactttc
     2461 ttctatatta tgactctaaa aagaaaggag acactatgac ctatttggaa aaatggtttg
     2521 acttcaatcg gcgtcagaaa gaaattgaaa gtctcttgga agagaccatt gcccaacaga
     2581 gcgagcaaag tctgaccttg aaagagttct acctgctcta ctatctggac ttggctgaag
     2641 aaaaatctct acgccagatt gacctgccag ataaacttca tctgagcccg agcgcagttt
     2701 ctaggatggt ggctcgcttg gaagctaaaa attgcggtct actcagtcgc atgtgttgcc
     2761 atcaagatag acgctctagt tttatctgcc tgacaaatga tgggcaaaag acactggcct
     2821 cgctacaaaa gactgtcgaa gaaagcttgg aagcaggttt ggatttcttg atttaagatg
     2881 attttaaaaa aagttgcgtg cgcaatcatt tttcttgaca ttctctttta taaggagtaa
     2941 aataaagtta gcattaaaca aaggagtttt aaatatgatt gaaattacct atatagatgc
     3001 cagcaagaac gaaagaactg tgactttcga gtcttatgaa gactttgaac gttcacaaca
     3061 agcttgcctt atcggcgtcg cagactacta ccctgtccaa aaattaactt acaagggtca
     3121 taatttggac taccatggga cttatggaga tatcttcttc tatctcatga aacaagattt
     3181 aagccaatat aactaaaaaa aggagaaata caatggcaaa agcaattaca gatgcaacat
     3241 tcgaacaaga aacaaaagac ggtttggtct tagtagactt ctgggcaact tggtgtggtc
     3301 catgtcgtat gcaaggtcca atcttggaca aattgtctga agaactttca gaagatgtct
     3361 tgaaaatcgt taaaatggac gttgatgaaa atccaaacac agctcgtgct tttggaatca
     3421 tgtctattcc aactcttctc ttcaaaaaag acggccaagt tgtcaaacaa gttgcaggtg
     3481 ttcacacagc agaacaaatc aaggccatca ttgctgaatt gagctaatca aacgagagac
     3541 caagtacttt ctttggtctc ttttttcttg ccctttgcca tttttcaaaa aatatgctag
     3601 actatagtag attgaaacta gaatagtaca cctctacttc taaaacattg ttaaaaatcg
     3661 atttgactgt cctgatcgat ttgtcctgtt tttatttcat tttactatat aagtagaata
     3721 ttacgatgtt tgggatatgc catcgctaaa aaaaaactcg atttggtatt ttttagttcc
     3781 ctaatgggag ctttttgcgt gctctgaaca tttcccattt tggaaggagt actatgaaac
     3841 atcaatcagc cttggtcgtc tttagtggcg gtcaagattc aacaacctgc cttttctgga
     3901 ccatgcaaca ctatgaaaca gtcgaagctg tcacctttgc ctacggccaa catcatcacc
     3961 tcgaaattca aattactaga gaaatcgcta aggaacaggg cattcgtcac catatcctcg
     4021 atatgtctct gctgggacaa atcactgctc agccagactt tgcgacgatt catatttcct
     4081 acattcctga caagctctgt gtcgagtcaa aatccctcaa actatatcta tttagctacc
     4141 gaaaccacgg agatttccac gaaaactgta tcaacaccat cgggaaagac ttggtcaact
     4201 tgctagaccc tcgctattta gaagtctggg gaaaattcac tccgcgcggt ggcatttcaa
     4261 tcgaccccta ctataactac ggtaagcaag gaactaagta tgagggcttg gcagaacaac
     4321 gcctcttcca acacgacctt tatccagaga aaattgacaa ccgctaaagt catactcaat
     4381 gaaaatcaaa gagcaaacta ggaagttagc cgcaggttac tcaaagcagt gtttgaggtt
     4441 gtagataaaa ctgacgaagt cagatcaaaa cactgttttg aggttgtgga tagaactgac
     4501 gtagtcagta accataccta cggcaaggta aagctgacgt ggtttgaaga gattttcgaa
     4561 gagtatcata cgaaaaagcc ctgttcctca agatgaggag caaggctttt tgagtttcaa
     4621 ttattcttct gttccaagga aattttttgc aacaagggct gcaagaactc caccagcgat
     4681 tggtgcaagg atgaaaatcc aaacttgttg aagggctgcg ccgcctacca agacagctgg
     4741 tgccaagcta cgagctgggt ttactgaaag tccagtaatc ttcaatccga caagaatcat
     4801 cgccatcaat gacaaaccga ttaccaaacc agcaatcgcg ccattgccct tgctttctga
     4861 agtcacagtc atgataacca atacaaacaa gaaagttgcg atgacttcaa acaagaaacc
     4921 accaaagaca gtgacaccgt ttgccaaggc attttcacca agactagcag ttgacatacc
     4981 tgaattactc aagaggaaga agactgcgcc agaagcgatg aaagctccaa caacctgacc
     5041 aaggatgtag tttacaagtt ctgaagatga caaacgtttg tttacaaaca tagcaatcga
     5101 aacagccggg ttcaagtgag cacctgaaac agttccgatt gagtaggctg ccaccacgat
     5161 tgccaaacca aaggcaaagg cgattccaag gtgaccaagg ccatcaagac catttccaaa
     5221 aacaacagct cctgttccaa cgaacacaag catgaacgta ccgattaact cagcaacaaa
     5281 ttttttcatt ttctttctcc ttttttcaaa aactagatac tagtctatca aaagtaggaa
     5341 agggtttcaa gaaaattgat tggaaatttt ttgaaaatca tagaactatt agctaatctc
     5401 tagtattgaa aagactggat agcttctttc aactcatctt gtaaactatt tctctggtca
     5461 agttggacat agacttccac cagacaggat ctaaagttgg aaaatttgta aaaatcctcc
     5521 ctttcttcta tcggaaaatc aacagttttt atccaagaag ctacttgttc ttgcgctaac
     5581 ttcccttgta aaataggttc atagatcact cttgctaaac gccaatcctc atcatctgta
     5641 aagcgaatcg acattctttt aaataattgg ccaagtatct caaatacttc atgaactctg
     5701 tttttaggaa agcccggatg acaaaccacc tctgtcagta aatcggctcc atgtgcaaaa
     5761 gcatgaaccc aaccatactg acttgaaaaa ccccttgtat ccttttcttt tgaaagatag
     5821 tgcaagcctt gatttaaaag gacattacga atttctggag aaggatttcc caaatgatca
     5881 aacaaccact ggatttcttc ctggttataa tttggttttt cttctgctat ttttcttagt
     5941 aaatcttgat acatggtcaa tacctctaca tttctagcaa ctgttcaaaa aggcagtctt
     6001 aaatgactca atattgaatt ctcaattaaa tacaatctga tataaaatga cgtaaataac
     6061 tatcaatacc agttctacag taagttcaaa tttaacatca cgatcttcaa cgacattttt
     6121 gaaaatagct acaactaaga caaatagaat gacgcttaac aagcccataa acatcattct
     6181 aaaaaatttt tctattcccc tactctccca actcagcact ataggagata atctggtcaa
     6241 ctgtgtcaga caagaattgg atggtatcac ggagtggttt gtctgttgaa atatcagcac
     6301 cgataatcat ggctgactca agtggtgtct tgctaccacc tgatttgagg agattgagcc
     6361 agtcttcagc tccagtttca gaatgtttta gatgaaggta accagcagtc gagataacta
     6421 gtcctgctga gtaagtgtaa ctatacaagc ccatatagta gtgagcttgg cgcatccaag
     6481 tcagagttgc atcatcgtca atttcaatag catctcccca gaaatccgtc aaaacttcct
     6541 tcataatgct gttgagcttg cttgctccaa aggtctcccc ttcttcaatc aatgtataca
     6601 ccttacgctg gaaggcggct tccaagaggt gggtgataaa gttatggaag taggtgtctg
     6661 tcaagcgatg agccagagcg aagcgttttt gacgtgggtc attagactgg ttctccaagt
     6721 aatcactgag tagcaattca ttgaaggttg acggtgcttc aacatagtag gtcgacatat
     6781 gggcattgaa gtaactttga tgattgtctg aaaagatgaa ttgaccagaa tgcccgattt
     6841 catgaatcaa ggtatagaca tcgctcaaac ggcctgtcca gctcatgagt acataagggt
     6901 gtacgcgata tgggtccgcc gcataaccac cggaatcctt gccactgtta gcagcaaagt
     6961 ccacccagcg ctcttcttgg taacgagcaa cttcctgaca atattcttgc cccaaaggtt
     7021 ctaccgactt catgaccaaa tcataggcat cgtcaatagt cacttcagga ttcagggcgc
     7081 tgtccaagtc caatttccag tctgcaaagg tcatcttttc aagaccattt accttggcaa
     7141 catgcttgag gtatctctga gcgactggtg caaagtcctt catgatgagg tcaatctggc
     7201 ggtcaaacat gacacggtcc acttcttgtt cagctagaag atagtcaaag acagagtcgt
     7261 atcccttcat atcagccaag agtttttcag acttgacctg agccagatag gctgctgcag
     7321 ccgtattttg gtgcttacga agtccctctg agaaggaacg gaaggatttc tcacgaacct
     7381 cagcatcctc atggttttgg tagaaattct cataggtcac aaagctgttt ttgtaggtct
     7441 tgccatgggc ttcaaagtca gccatttcaa aatccccagc tcgcatctta gtataaatgt
     7501 cctgcggact gtagaaaact tcaccgagat ttgtcaaggc cttctccaca tctgccccta
     7561 agtagtgggc ttttttgatt ttagcctgac gaatggcagc tgttaaatgt ggcaatttac
     7621 ccaaacgatc caagacttcc tcgtctgctg ccaccaaggc atcgtcaaaa aaggtcaagg
     7681 ctacgctggc atctgtttca aattccatcc cagcttgagc aatatttgca aattcgtcat
     7741 tgctatagtc cgtcgtctga ggcataaaac catagttgcc aatatggctc atctgaatgt
     7801 agatctgttc caattccgca aaggccttct cgaaatcctc aaaagtgtga agattgccct
     7861 tgtaatcacg gctaaactgg ttgatgtctt cgcgagcttt ctcgattgca cgcaagaaat
     7921 cctcacggtc ttggtataga gctgttaaat cccaaagttc cttctctgga aattctgaac
     7981 ggtgtttttg ttccattttc ttcctcttat ttctctaatt ctactaaaac actaagggct
     8041 gataaggcgt aaagcggtgc tgtttctgct cttagaatgc gagggccaag tcctgccaaa
     8101 acagctccct tagcttcaaa attttcaatt tccgcaggtg acagaccacc ttctggacca
     8161 aagataaaga gcaatttggc tcctttctcg agtccagtaa ctgcttttat aagagcagcg
     8221 gcttctcctt ctttggccgc ctcttcatag gctactaaga tgcggtcaaa ctggtcaagt
     8281 tgggctagaa agtctgcttt attctcgaaa agatggatac ttggaacaac attacgctta
     8341 ctttgctctg ctgctccaag agcaattttt tctagttttt caaccttttt acccaatttc
     8401 ttgccatccc acttagcaac ggaccaatcg gcagggaagg cccaaatctg gctggcacct
     8461 agttccgtca ccttttgagt gataaactcc aacttatctc ccttgggaaa tccagatgcg
     8521 atggtcactt ggactggtag ttccacattg tcatttaatt cttggaccaa ctcaaactga
     8581 cgattttcca tatccagcac gcgcgccaag cgcttgatgc catcatcaaa gactaaggta
     8641 acctcatcct cttctttcaa gcgcataacc tgaaacatat gcttgctggt ttccctgtcc
     8701 tcgatggtga caggagagac tgcactcccc ttgacaaaat actgttgcat gctagcctcc
     8761 aatcacacct gaaatatcct tggtcttctt gaagacgcag gcattccatt ccccttgaat
     8821 catatgggtt tcaaggaaaa atccagctga ctcagccgac tggcgcacca tgtcccactt
     8881 gtccttgata atgccactca tgatgaggta gccttcatcc tttaccaagc gataagcatc
     8941 ctccgtcaga tgaatgagaa tatccgccaa gatattagcc acgatgacat ctgcttcaat
     9001 ctcaactccc ttaagcaagt ctcctgctgc tacatggata ttttccatac cagtgttgag
     9061 ctcaatattt tcctgagcga cacgaaccgc cacatcatcc aagtcatagg cgaaaatctc
     9121 cttggcacct aggagtgagc ttgcaataga aagaacccct gaaccagtcc ccacatctag
     9181 caccgtttcg ccaccacgaa gaacctgttc caaggcaaaa aggctcatct tggtagttgg
     9241 gtgggttcca gtaccaaaag ccatgccagg atccagcttg ataatttttt ctcccgcagt
     9301 cgcctcatag tctgtccaag agggaacgat ggtcaaatca tgagtgatgc gagcaggttc
     9361 atagtatttc ttccagttgt ctgcccagtc ttcctcagcc aaggcagtcg tacctatttt
     9421 taactctccc aaatccataa aatccgtcaa ttctgctaag cgagcctgca agtccgcctc
     9481 aaccactgtc atatccaccg tgtcagggta gtaggctgtc actacgattt cttcttgctg
     9541 ctccacctct gggaaaatct cgccaaaacg atccacattt cccatatagt ccatgctgtc
     9601 ttcaatcgcg actccttgcg ctcccagctc aatcaagaga ttggaaacca actcctctcc
     9661 ctcacgcttc actgtaactt ttaactcttg ccatgtttcc attattaaga taccaagccc
     9721 gtaaaacaca aaaccaaaat aggaaattct ctgaagacgc ttgtgtctaa gagaagttta
     9781 tctttttggc acagtgttta gggcgggttc agtttagaaa tgtaactgaa ccatcctttc
     9841 taatcactta cttttaaata atcttttaat ctctcttgca actgaggcac aacttgactg
     9901 gaactaagaa attcctcaac attcatcagc tgatagccct gtccttcatc tccgaagatg
     9961 atattgtcaa attgttcttg tcttagctga ccaaccataa agaccgattt cttgccttta
    10021 aaaattacgc taggataaat cttgctccaa agcagacagt cttcatctaa atgaattccc
    10081 agttcctcat aaacttcacg ccgagcgcat tcaaaagggc tttcgtcccc ttcacggcca
    10141 ccacctggca actcccacat gttgggacaa gggatatcgt ccttgtcatc acgcaaaatc
    10201 gtcagtagct tatccccaca aaagagggca atcttgcaac cttggaaatc agaaatttct
    10261 agttccatct tcagttcctt ctaacatttc cttttccagc tctgctaaca agttttcata
    10321 atagcgtttc tcgtccctca acattcgact actatccatt ttctgtctag caatcttgag
    10381 agccttacga gttcgatcta catctttctt cacctttaat tgataccagg cttgtatcac
    10441 ttgaagattg gacagtttga gagacagaaa cgatttgacc tgtcgaatac tagcatattg
    10501 ctccgcttgc tcaaaatctc cttccaacaa ggcgatatga agcagggata gttgggcaac
    10561 tgtctgcatc atcggagtag ttgtcctctc aagtaatgct tgaaactgct gtttagctac
    10621 ttcttccttc ccttccaaaa tggaaacttc accttgcata cctaatacac catccgcaaa
    10681 actccctcgt gcatcctcag gaactgcttg aacaaagtct ttcaaatcat attcttgagg
    10741 agccagcaaa gtttgagcag aatgtctcaa taccaggtag gcgtatttgg tattttcagg
    10801 gtgttgtagt aattcccaaa tttttgctcc atcggtgatg tcgactggca aaatgttatt
    10861 taggaagaaa gataaattaa gaaaaatcca agtccctgca aaataccagc ttcttgtcaa
    10921 aaatccaaac actatcgcca ataatatcaa gccgagatga accatcaagc ctcctgaaag
    10981 catcaggatg attctttgat cgctttcatc ctcttttaaa ccaatgtatt gagcaccaac
    11041 atttttcaga atggctgttc tactaagatg aaacctgcct gactttttgg tcaaaataaa
    11101 atgtcctaat ccaaaagcca ccagccgata gcctgtcaag tagccacaaa aagcatgacc
    11161 cagctcatga agaataaaga ttaaatacat gcttagaaga gcgaaggcat aaccaaaagt
    11221 aaaggctaaa actgcggaat accccaactc tgcaaatgcg attgttccac aagcaaaagc
    11281 tagcataata aagacaacag ctagcacata aaccaaataa gtcccaattt tcttcataac
    11341 acctccaacc aactcctagt atcttggata aggataaaat tctccctctt ccaagccaac
    11401 ttttccttct tcaaagactt cttggttcca ttccatgaca aattcctctg cttctgggtc
    11461 ttccaaaaag tccatgagga catctagccc aacctcagca gtatctttaa ggaaaagcac
    11521 aaaataagct aaaaattcac gggaaaatcc ttttttaggc aggtaaggaa taacagtcaa
    11581 atagtcttcc tcattgactg ttgacttagc aggattgtag aaaaggaccg cttcctcaaa
    11641 aagaatgtca tctgatgaaa cctctccgtc ttcatccacc atctccacac ctgcagcatt
    11701 ttgcgcttcc aatagaaaac tcacttctac cgcatggttg cgtttgtccc agctaatctc
    11761 aaagtcaaag ggaaagttct tgtccaactc ttcctctaaa acatctaaaa atccgtatgt
    11821 tgccattttg tcctctttct atgcgactct ttaatcgccc cgattgctcg gaaatatgct
    11881 aaaatagata ctaccatctt accacaaaat tattttatgt cctaattata ccatattacc
    11941 tcatttaaac ccttggtatc agtgattttc ttaaaagtct gatttcttca tttctcataa
    12001 aaatcaatat aaaaagccct cgaaagggct aataaatcta taaaatcaat aggcgagtaa
    12061 ctagcacaag tggacgtgct tttttattga ctattaccac gataccacgc ttaatcttag
    12121 gcttgaactt tcttatctgc aatagcgtct gtcaaagtct gagaaaagtt aagtcccatt
    12181 tctcgtccca acttatctgc ccattttggt atggtcaaag tctttttaat gggttcctga
    12241 cttcctaggt attctgatac atcaacagat accatagaaa taaaagattt atcaaggtca
    12301 taggttgaca cgaaatcttc atcatcttta aaaggatcat tatcaattaa agacaagcta
    12361 ttgatatctg atggctgagg taactctcca tcactctcta tcaaatctgc aacagttatc
    12421 cctagccact ccgaccccat agccaaagcc tcagaaatcc cctctccttg tgtagctgag
    12481 tattcaaaat ctgggaaatg gacaaaataa gtcgcttctg ttccgtctgt gtcgtcataa
    12541 taaaataaag ctggatacgt aactaacatt tcactacctc catatcaaaa agcagggact
    12601 gaattttaca acccagcttg ctttcctatc cctctttcag tgtacttatt cagctcacca
    12661 tgaaggattg tgataggtct ttccccttgc ttctcgattt taatatggga gcctttaccg
    12721 cctctagtct ttatccaacc atgggccgta aagagtttaa ccatctcttt ttgtgtcata
    12781 ggcatagcgc ttttacctcc tgacaacacc attataacac gtgttacacg tattgtaaag
    12841 gagtgatact tattattcta ttatacataa aagcccctag atgtggttct aagggaaacc
    12901 aatttattca gacctatttt tctaatgagt agtaaaaact gcttctttat cgagcaattc
    12961 atcatctgta tagtcaattg taaaagtatc tcgatctaag acagattgag gcggagttga
    13021 atgaatcata ggaccactgc gtactctata ttttttatct ccaattttta caaactgata
    13081 ctcttcgaaa atcaaattca aaccacgtca acgtcgcctt accgtactca agtacagcct
    13141 gcggctagtt tcctagtttg ctctttgatt ttcattgagt atgattaact ctcaagtctt
    13201 cgaaatcagg attttcaaca gttattacaa ggaggcgatt tactacttca aaaacatcaa
    13261 ttattctatt tttcatattt tttcaaccca ttattagaat gaacttcttg gtaagcaaaa
    13321 tcaagtttag atttaatgtt ttcgtacaaa tctaaaatct cttttggagt atcttcccgg
    13381 aagaaaagtt ttcttttccc tgaaataact tgatcactaa gaatccaatg acgaatttgt
    13441 tttgtaaaaa t
//
LOCUS       DAVBEO010000056        12673 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 009
            SAMEA1678075-rid20185393.denovo.056, whole genome shotgun sequence.
ACCESSION   DAVBEO010000056 DAVBEO010000000
VERSION     DAVBEO010000056.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678075
            Sequence Read Archive: ERR226392
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12673)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12673)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980207.1
            Genome Coverage       :: 150x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:50:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 72 of 147
            Pseudo Genes (incomplete)         :: 72 of 147
            Pseudo Genes (internal stop)      :: 42 of 147
            Pseudo Genes (multiple problems)  :: 32 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12673
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678075-rid20185393.denovo.056"
                     /strain="KS 009"
                     /db_xref="taxon:1313"
     gene            <1..209
                     /locus_tag="VQ543_001787"
     CDS             <1..209
                     /locus_tag="VQ543_001787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET2612463.1"
                     /translation="RKSSKLKPLTVEDKACNHALSKERSKVENIFAKVKTFKMFSTTY
                     RNHRKRFGLRMNLSAGIINHELGF"
     gene            359..613
                     /gene="blpM"
                     /locus_tag="VQ543_001788"
     CDS             359..613
                     /gene="blpM"
                     /locus_tag="VQ543_001788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000379879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-peptide bacteriocin subunit BlpM"
                     /protein_id="HET2612464.1"
                     /translation="MDTKIMEQFHEMDITMLSSIEGGKNNWQTNVLEGGGAAFGGWGL
                     GTAICAASGVGAPFMGACGYIGAKFGVDLWAGVTGATGGF"
     gene            629..832
                     /gene="blpN"
                     /locus_tag="VQ543_001789"
     CDS             629..832
                     /gene="blpN"
                     /locus_tag="VQ543_001789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001099492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-peptide bacteriocin subunit BlpN"
                     /protein_id="HET2612465.1"
                     /translation="MNTYCNINETMLSEVYGGNSGGAAVVAALGCAAGGVKYGRLLGP
                     WGAAIGGIGGAVVCGYLAYTATS"
     gene            1076..1225
                     /gene="blpO"
                     /locus_tag="VQ543_001790"
     CDS             1076..1225
                     /gene="blpO"
                     /locus_tag="VQ543_001790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpO"
                     /protein_id="HET2612466.1"
                     /translation="MDTKMMSQFAVMDNEMLACVEGGDIDWGRKISCAAGVAYGAIDG
                     CATTV"
     gene            1329..1448
                     /locus_tag="VQ543_001791"
     CDS             1329..1448
                     /locus_tag="VQ543_001791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000346296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin"
                     /protein_id="HET2612467.1"
                     /translation="MDFKSFIIGLVVGIFGPYMDDLIRKIFSKSSKKDTDSTL"
     gene            2234..2632
                     /locus_tag="VQ543_001792"
     CDS             2234..2632
                     /locus_tag="VQ543_001792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000877383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="immunity protein"
                     /protein_id="HET2612468.1"
                     /translation="MKYRLFFVIFLSSVLDILLGTFLQISIVSIGWLVLYSGLFEVGV
                     FLLANKGVAVKIKEVDIRNRFKFIFGKTLWFQILLLIFLIIKLYLGLDARLILFYGHI
                     FIVFNALMYLLSSSQVSLKKKQTVFLILQQ"
     gene            2670..3359
                     /locus_tag="VQ543_001793"
     CDS             2670..3359
                     /locus_tag="VQ543_001793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000760553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET2612469.1"
                     /translation="MKKYQLLFKISAVFSYLFFVFGLSQLTLIVQNYWQFSSQIGNFV
                     WIQNILSLLFIGVMIVVLVKTGHGYLFRIPRKKWLWYSILTVLVVVFQISFNVQTAKH
                     VQSTAEGWAVLIGYSGTNFAELGIYIALFFLVPLMEELIYRGLLQHAFFKHSRFGLDL
                     LLPSILFALPHFSSLPSLLDIFVFATVGIIFAGLTRYTKSIYPSYAVHVINNIVATFP
                     FLLTFLHRVLG"
     gene            3401..3649
                     /locus_tag="VQ543_001794"
     CDS             3401..3649
                     /locus_tag="VQ543_001794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2612470.1"
                     /translation="MYKHLFFLDSKTLDRLTPYILVLASDTIAFNVFVLTFVSAVVFN
                     FLNSMLALMAIFIGAGYVVGFWLLKWFVLERLELKDDA"
     gene            3679..4290
                     /locus_tag="VQ543_001795"
     CDS             3679..4290
                     /locus_tag="VQ543_001795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000394041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET2612471.1"
                     /translation="MEFFDKFHALCFGFLVLIIVITVPYTINHGGFFQNESALILVSL
                     LVTSLSVAYARKFEMISFGMLSKKQLLLFIAIFLLSVLETLVYIHFFAVSSGSGVQHL
                     AEVSRGISLSLILTTSVFGPIQEELIFRGLLQGAVFDNSWLGLVLTSSLFSFMHGPSN
                     VPSFIFYLLGGLLLGFAYKKSQNLWVSTLVHMFYNSWPLLYYL"
     gene            4451..5245
                     /locus_tag="VQ543_001796"
     CDS             4451..5245
                     /locus_tag="VQ543_001796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000363010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphotransferase family protein"
                     /protein_id="HET2612472.1"
                     /translation="MDLGDNELTLTPIPGKSGKAYMGSYPDGKRIFVKMNTSPILPGL
                     AREQIAPQLLWSRRLADGRDMCAQEWLTGKILTPYDMNRKQIVNILTRLHRSRPLMTQ
                     LSRLGYAMETPVDLLQSWQETAPDALRKNHFISEVMADLRQTIPGFREDHATIVHGDV
                     RHSNWIETDSGLIYLVDWDSVRLTDRMFDVAHMLCHYISEHQWKEWLTYYGYKYNQTV
                     LSKLYWYGQLSYLSQISKYYMNQDLENVNREIHGLRHFRDKYGKRR"
     gene            5242..5877
                     /gene="trmB"
                     /locus_tag="VQ543_001797"
     CDS             5242..5877
                     /gene="trmB"
                     /locus_tag="VQ543_001797"
                     /EC_number="2.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001266107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(46)-N7)-methyltransferase TrmB"
                     /protein_id="HET2612473.1"
                     /translation="MRVRNRKGATELLEANPQYVVLNPLEAKAKWRDLFGNDNPIHVE
                     VGSGKGAFVSGMAKQNPDINYIGIDIQKSVLSYALDKVLEVGVPNIKLLWVDGSDLTD
                     YFEDGEIDRLYLNFSDPWPKKRHEKRRLTYKTFLDTFKRILPENGEIHFKTDNRGLFE
                     YSLVSFSQYGMKLNGVWLDLHASDFEGNVMTEYEQKFSNKGQVIYRVEAEF"
     gene            6003..6482
                     /gene="rimP"
                     /locus_tag="VQ543_001798"
     CDS             6003..6482
                     /gene="rimP"
                     /locus_tag="VQ543_001798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000338698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimP"
                     /protein_id="HET2612474.1"
                     /translation="MDAIATIVELVREVVEPVIEAPFELVDIEYGKIGSDMILSIFVD
                     KPEGITLNDTADLTEIISPVLDTIKPDPFPEQYFLEITSPGLERPLKTKDAVAGAVGK
                     YIHVGLYQAIDKQKVFEGTLLAFEEDELTMEYMDKTRKKTVQIPYSLVSKARLAVKL"
     gene            6526..7662
                     /gene="nusA"
                     /locus_tag="VQ543_001799"
     CDS             6526..7662
                     /gene="nusA"
                     /locus_tag="VQ543_001799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusA"
                     /protein_id="HET2612475.1"
                     /translation="MSKEMLEAFRILEEDKGIKKEDIIDAVVESLRSAYRRRYGQSDS
                     VAIDFNEKTGDFTVYTVREVVDEVFDSRLEISLKDALAINSAYELGDKIKFEEAPAEF
                     GRVAAQSAKQTIMEKMRKQTRAITYNTYKEHEQEIMSGTVERFDNRFIYVNLGSIEAQ
                     LSKQDQIPGEVFASHDRIEVYVYKVEDNPRGVNVFVSRSHPEMIKRLMEQEIPEVYDG
                     TVEIMSVAREAGDRTKVAVRSHNPNVDAIGTIVGRGGANIKKITSKFHPARYDAKNDR
                     MVPIEENIDVIEWVADPAEFIYNAIAPAEVDQVIFDENDSKRALVVVPDNKLSLAIGR
                     RGQNVRLAAHLTGYRIDIKSASEFEAMEDAASVELEVENDTVEE"
     gene            7684..7977
                     /locus_tag="VQ543_001800"
     CDS             7684..7977
                     /locus_tag="VQ543_001800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000857559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxR family protein"
                     /protein_id="HET2612476.1"
                     /translation="MKTRKIPLRKSVVSNEVIDKRDLLRIVKNKEGQVFIDPTGKANG
                     RGAYIKLDNAEALEAKKKKVFNRSFSMEVEESFYDELIAYVDHKVKRRELGLE"
     gene            7970..8269
                     /locus_tag="VQ543_001801"
     CDS             7970..8269
                     /locus_tag="VQ543_001801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxQ-related RNA-binding protein"
                     /protein_id="HET2612477.1"
                     /translation="MNKQKISNLLGLAQRAGRIISGEELVVKAIQDGKAKLVFLAHDA
                     GPNLTKKIQDKSHYYQVEIVTVFSTLELSIAVGKSRKVLAVTDAGFTKKMRSLME"
     gene            8286..11078
                     /gene="infB"
                     /locus_tag="VQ543_001802"
     CDS             8286..11078
                     /gene="infB"
                     /locus_tag="VQ543_001802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-2"
                     /protein_id="HET2612478.1"
                     /translation="MSKKRLYEIAKELGKESKEVVARAKELGLDVKSHSSSVEEAVAA
                     KIAASFKPAAAPKVEAKPAAPKVSAEKKAEKSEPAKPAVAKEEAKPAEPVAPKTEKVA
                     VKPQSRNFKAEREARAKEQAERRKQNKGNNRDQQQNGNRQKNDGRNGGKQGQSNRDNR
                     RFNDQAKKQQGQQKRRNERRQQEDKRSNQAAPRIDFKARAAALKAEQNAEYARSSEER
                     FKQYQAAKEALAQANKRKEPEEIFEEAAKLAEQAQQVQAVVEVVPEKKEPAVDTRRKK
                     QARPDKNRDDYDHEEDGPRKQQKNRSSQNQVRNQKNSNWNNNKKNKKGNNKNNRNQTP
                     KPVTERKFHELPTEFEYTDGMTVAEIAKRIKREPAEIVKKLFMMGVMATQNQSLDGET
                     IELLMVDYGIEAKQKVEVDNADIERFFVEDGYLNEDELVERPPVVTIMGHVDHGKTTL
                     LDTLRNSRVATGEAGGITQHIGAYQIVENGKKITFLDTPGHAAFTSMRARGASVTDIT
                     ILVVAADDGVMPQTIEAINHSKAANVPIIVAINKIDKPGANPERVIGELAEHGVMSTA
                     WGGDSEFVEISAKFNQNIEELLETVLLVAEIQELKADPTVRAIGTVIEARLDKGKGAV
                     ATLLVQQGTLNVQDPIVVGNTFGRVRAMTNDLGRRVKVAGPSTPVSITGLNEAPMAGD
                     HFAVYEDEKSARAAGEERAKRALMKQRQATQRVSLENLFDTLKAGELKSVNVIIKADV
                     QGSVEALSASLQKIDVEGVKVTIVHSAVGAINESDVTLAEASNAFIVGFNVRPTPQAR
                     QQAEADDVEIRLHSIIYKVIEEMEEAMKGMLDPEFEEKVIGEAVIRETFKVSKVGTIG
                     GFMVINGKVARDSKVRVIRDGVVIYDGELASLKHYKDDVKEVTNGREGGLMIDGYNDI
                     KMDDVIEAYVMEEIKR"
     gene            11329..11679
                     /gene="rbfA"
                     /locus_tag="VQ543_001803"
     CDS             11329..11679
                     /gene="rbfA"
                     /locus_tag="VQ543_001803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001273594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosome-binding factor RbfA"
                     /protein_id="HET2612479.1"
                     /translation="MANHFRTDRVGMEIKREVNEILQKKVRDPRVQGVTITDVQMLGD
                     LSVAKVYYTILSNLASDNQKAQIGLEKATGTIKRELGRNLKLYKIPDLTFVKDESIEY
                     GNKIDEMLRNLDKN"
     gene            complement(11739..12673)
                     /locus_tag="VQ543_001804"
                     /pseudo
     CDS             complement(11739..12673)
                     /locus_tag="VQ543_001804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         3887 a         2212 c         2869 g         3705 t
ORIGIN      
        1 cacgtaaatc cagcaaactc aaaccgctaa cagttgaaga taaagcctgt aaccatgcgc
       61 tatctaagga gagaagcaag gttgagaaca tctttgccaa agtaaaaacg tttaaaatgt
      121 tttcaacaac ctatcgaaat catcgtaaac gcttcggatt acgaatgaat ttgagtgctg
      181 gtattatcaa tcatgaacta ggattctagt tttgcaggaa gtctaatgta atttttgcaa
      241 ttcaagacgt ttcgatgact attcaagatc tggatgaaaa attttaaaaa acgatgatat
      301 actaaacttg tcaaagttac aacaagacaa aaattaaaaa taaaaaagag tatttgtcat
      361 ggatacaaaa attatggaac aatttcatga aatggatata actatgttat ctagtattga
      421 aggaggcaag aataattggc aaactaatgt cttggaaggt ggtggtgctg cttttggtgg
      481 ctgggggcta gggacagcta tttgtgctgc gagtggtgtt ggagcaccat ttatgggagc
      541 atgtggatac ataggagcta aatttggtgt ggatctttgg gcaggagtaa caggggcaac
      601 gggtggattt taataaaagg agacttgtat gaatacttat tgtaatataa atgaaacaat
      661 gctgagtgag gtttatggag gtaattccgg aggagcagct gtagttgctg ctttaggttg
      721 tgcagcgggt ggagtgaaat atgggagact tctaggacca tggggcgctg caataggagg
      781 aattggagga gcagtggttt gtggatattt agcctatacc gctacatcat aaaaatgaaa
      841 gctaaatttt atgaaggcta tattctttat tattctcttc gcttttcaaa cctatcttat
      901 ttatctatcc ataagtatct ccgataaaaa acaaaagact attgaattaa catcattgaa
      961 ttgttttgtc atattatttc taatctatga taaattaatt tttctcttta ttgcctatgt
     1021 ttttttgata atttttatat taaacttgtt ccgtaactga aaagtgatat actatatgga
     1081 tacaaaaatg atgtcacaat ttgcagttat ggataatgaa atgcttgctt gcgttgaagg
     1141 tggagatatt gattggggaa gaaaaattag ttgtgcagca ggggttgcat atggcgcaat
     1201 tgatgggtgt gcaacaacgg tttgacattt ctattgggac catttgctat aggaataggt
     1261 gtaactggtg ctgcaggtgg agctatactt ggaggtgtag cctatgcagc aatatgttgg
     1321 tggtaattat ggattttaaa agttttatta ttggtttagt agttggtata tttggtcctt
     1381 atatggatga cttaattaga aaaatatttt caaaatcttc caaaaaggat acggatagta
     1441 ctctctaaaa aataaatttc tcccctgtat ttgctagctt aatttacagg ggagtttctt
     1501 taatattgtt tcgcctgtca aaatgatatg tgatagcagg atgaaaagtc tacaaacaag
     1561 ttggtatcaa tacaatataa agaggaaagt atgtttttaa tgcttacttt ttaaattttt
     1621 taacaattca agatgtttcg atgacaattc aagatttgga tgaaaaattt taaaaaacaa
     1681 tgatatacta aacttgtcaa agttgcaacg ggtgctgcta cattatgtta aaaatcgctc
     1741 ttgattgata agctggattt gttaggaaag gagtaaataa ttatggataa gaaaaagata
     1801 gtttcgacta taatatgtat agtatttctt gtagtgtcag tagataattt ttttagagac
     1861 ttaaccccgt tactgttcat tttaaatatt attggcctgt cttgcttttc agtgctaaca
     1921 tacattaaca taaaagagat actcttaaat ataagtaaat gatgatttgg ttagtcctag
     1981 aaccaatcaa cttatgttta tcggcttggc agattttatg tttgtcattt gtttgtatag
     2041 aggtatttca gaaacagaat tctatcaaca actaatcgct tatataggtg tattctctgc
     2101 ttgtttatca cgcttctgct catgtggggc ttgaagtatt ataaaaagta gctttctatc
     2161 cttttctgac aggatatttg agtagaaggc tctattaaat tgttagtgaa ataaatgaat
     2221 ggaggtattt aatatgaaat acagattatt ttttgttatt ttcttgagta gtgtgttgga
     2281 tattctttta gggacatttt tacaaatctc tatcgtatct attgggtggc ttgttcttta
     2341 cagtggtttg tttgaagtag gagttttcct tcttgctaat aaaggggtgg cggtaaaaat
     2401 caaggaagta gatattcgaa atcgctttaa atttattttt ggaaaaacct tatggtttca
     2461 aattcttttg ctcatctttt tgataatcaa actttatctt ggtttggatg cgaggttgat
     2521 tttattctat ggacatattt tcattgtctt taatgcctta atgtatctat tatctagtag
     2581 tcaggttagc cttaaaaaaa aacaaactgt cttcttaatc ttacagcagt agagtctgac
     2641 aaggtgaggt catagtaggg aggatttcta tgaaaaagta tcaacttcta ttcaaaataa
     2701 gtgcagtctt ctcttactta tttttcgtat ttggtctttc tcagctgacg cttatcgtcc
     2761 aaaattattg gcaattttct tcccagattg gtaatttcgt ctggattcaa aatatcttga
     2821 gtttactttt tattggagtc atgattgtgg ttcttgttaa gacaggccat ggttatctct
     2881 tccgcattcc aagaaaaaaa tggctttggt attcgatttt gacagtatta gtggtagtgt
     2941 tccagatctc ttttaacgtt cagacagcta aacatgttca gtcaactgcg gaaggttggg
     3001 ctgtattgat tggttatagt gggactaact ttgcagagct aggtatttat atagccctgt
     3061 tctttctggt tccactgatg gaagaattga tttatagagg attactgcaa catgctttct
     3121 ttaagcattc gcgatttggt cttgatttgc ttcttccttc tattttattt gctctccctc
     3181 atttttcaag cctgcctagt ctgttagata tcttcgtctt tgcaacagtt ggaatcatct
     3241 ttgctggttt gacccgctat accaagagca tttatccatc ctatgcggtg catgtgatca
     3301 ataatattgt agcgaccttc ccgtttttgc tcacttttct acatagggtc ttggggtaaa
     3361 aaaacaaaag gcttgctttt cagccataga ggaggtcatc atgtataaac acttattttt
     3421 cctagattcc aaaactttag atcggttgac accctatatt ctagtcttgg cttctgacac
     3481 cattgctttt aatgtttttg tgctaacctt tgtatctgcg gtggttttta atttcctaaa
     3541 ttccatgcta gctttaatgg ctatattcat aggggctggc tatgtggtcg gattttggtt
     3601 gctaaaatgg tttgttttgg aaaggttaga gctaaaggat gacgcgtagg aagtctgttt
     3661 ggtgaggagg atagttttat ggagtttttt gataaatttc atgccttgtg ttttggattt
     3721 ttagtactaa taattgtcat tacagttcct tatacgatta accatggggg tttttttcaa
     3781 aatgaatctg cattgattct tgtaagtctt cttgtaacct cgctgagtgt tgcttatgct
     3841 agaaagtttg aaatgatttc ttttgggatg ttaagcaaga aacaactttt gcttttcatt
     3901 gcaatctttc ttctaagtgt acttgagacg ctggtttata ttcatttctt cgctgtttct
     3961 tctggctcag gggtccaaca cttggcggaa gtcagcagag gaatttccct gtctttgatt
     4021 ttgactacct cagtttttgg ccccatccag gaggaactca ttttcagagg acttcttcaa
     4081 ggtgcggttt ttgacaattc ttggttaggg cttgtgctaa cttcctctct cttttctttc
     4141 atgcatggac cttctaatgt cccttcgttt attttttatc tacttggggg tttgttgctg
     4201 ggctttgctt ataaaaagag tcaaaaccta tgggtttcta ctctagtaca catgttttac
     4261 aacagttggc cactcctata ttatttataa aaattatgaa aaggtaagca gaagacggtg
     4321 cttacctttt tcaagctata atgataccca agccaatcca gaggcttttc tttgagaatc
     4381 gggttagagt ggttgacgaa taggccaaaa actagtagaa tagtaaggaa actttatacg
     4441 gaggaaagaa atggatttgg gtgataatga gctaacactg actcccatac ctgggaaaag
     4501 tggcaaggct tatatgggta gctatcctga cgggaagcgc atctttgtaa aaatgaacac
     4561 ctctccaatc ctacctggtc tagctagaga acaaattgct ccacaattat tatggagtcg
     4621 tcgtttggca gatgggcgtg atatgtgtgc tcaagaatgg ttgacaggca agatattgac
     4681 cccctatgat atgaatcgta agcaaatcgt caatatttta acccgtcttc atcgctcacg
     4741 tccgttgatg acacaattga gtcgtttggg ctatgccatg gaaacacctg tagatttact
     4801 acagtcttgg caggaaacgg ctccagatgc tttgcgtaaa aatcatttta tcagtgaagt
     4861 gatggctgat ttacgtcaga ctattccagg atttagagag gaccatgcga ccattgtcca
     4921 tggagatgta cgacatagta attggattga gacagatagt ggcttgattt atttagtaga
     4981 ttgggattcg gttcgcttga ccgatcgcat gtttgatgtg gcccatatgc tctgccatta
     5041 tatttcagaa catcagtgga aggaatggtt gacctactac ggttacaagt acaatcaaac
     5101 ggtattaagt aaattgtatt ggtatggtca attgtcttat ttgagtcaga tttccaagta
     5161 ttatatgaac caagatttag aaaatgtcaa tcgggagatt catggtttgc gtcatttccg
     5221 agacaagtat ggaaagagaa gatgagagtt agaaatcgta aaggggcaac agaattacta
     5281 gaggcaaatc cccagtatgt ggtcctcaat cccttggaag ccaaggcaaa atggcgggac
     5341 ttgtttggca atgataatcc cattcatgtg gaagttggaa gtggaaaggg tgcctttgtt
     5401 tcaggtatgg ccaagcaaaa ccctgacatc aactatatcg ggattgatat tcaaaagtct
     5461 gttttgagct acgctttgga caaggtgctt gaagttggag tgcctaacat caagctcttg
     5521 tgggtagatg gttctgactt aactgactat tttgaagacg gtgagattga tcgcttgtat
     5581 ctgaactttt cagatccatg gccgaaaaaa cgccatgaaa agcgtcgttt gacctacaag
     5641 accttcttgg ataccttcaa acgtatcttg cctgaaaatg gagaaattca tttcaagacg
     5701 gataaccgtg gcttgtttga gtacagttta gtgagctttt ctcaatatgg catgaaactc
     5761 aatggtgtct ggttagattt gcatgccagt gattttgaag gcaatgtcat gacagaatac
     5821 gagcaaaaat tctcaaacaa ggggcaagtt atctaccgag ttgaggcaga attttaagag
     5881 atagcctaaa attaggctgt acaagtgctt ttgctttaca taagttggca aacgtgctat
     5941 actgatagta agaatatgaa aagtgaggcg gggaaatatc ttcgcctctt gcttatgagg
     6001 aggtggacgc aatcgcaaca atcgtagaat tagtcagaga agttgtagaa cctgtcatag
     6061 aagctccttt tgaactcgtg gatatcgagt atggaaagat tggcagtgac atgattctca
     6121 gtatttttgt agataaaccc gaaggaatta ccttgaacga cacggcagac ttgacagaaa
     6181 ttatcagtcc tgtcctagac accatcaagc cagatccctt cccagaacaa tatttcctag
     6241 aaattaccag tccaggtttg gaacgccctt tgaaaaccaa ggatgccgtc gctggagcgg
     6301 ttggaaaata catccatgtc gggctctacc aagccatcga taagcaaaag gtctttgaag
     6361 gaaccttgtt ggccttcgaa gaggacgagt tgactatgga atatatggac aagacgcgta
     6421 agaaaaccgt ccaaattcca tacagtttag tatcaaaagc acgtttagca gttaaattat
     6481 agaaaaagaa aggatagctt ttgaggattc aaaagtgaag aaaacatgag taaagaaatg
     6541 ctagaggcct tccgcatttt ggaagaagac aagggaatca aaaaagaaga tatcatcgac
     6601 gcagtagtag agtcgcttcg ttccgcttat cgcagacgct atggtcagtc agacagcgta
     6661 gctattgact tcaacgaaaa aacaggtgac tttacagttt atactgtccg tgaagttgtt
     6721 gatgaagtat ttgatagccg tttggaaatc agcttgaaag atgctcttgc cattaattca
     6781 gcttatgaac ttggagacaa aatcaagttt gaagaagcac cagctgagtt tggtcgtgta
     6841 gcagcccagt ctgccaaaca aaccatcatg gaaaaaatgc gcaagcaaac acgtgccatc
     6901 acttacaata cttacaaaga acatgagcaa gaaatcatgt ctggtacagt agaacgcttt
     6961 gacaaccgct ttatctatgt caaccttggt agcatcgaag cccaattgtc aaaacaagac
     7021 caaattcctg gagaagtttt tgcttctcat gatcgtatcg aagtttatgt ttacaaggtt
     7081 gaagacaacc ctcgtggtgt gaacgtcttt gttagccgta gtcatccaga aatgatcaaa
     7141 cgtttaatgg agcaagaaat tccagaagtt tatgatggaa ctgttgaaat catgagcgtg
     7201 gctcgtgaag caggtgaccg tacgaaggtt gctgttcgta gccacaatcc aaacgtggat
     7261 gctatcggta caatcgttgg acgtggtggt gctaatatca agaagattac tagcaaattc
     7321 cacccagctc gttacgatgc taaaaatgac cgcatggtac caatcgaaga aaatatcgat
     7381 gttatcgagt gggtagcaga tccagctgaa tttatctaca atgccatcgc tcctgctgag
     7441 gttgaccaag ttatctttga tgaaaacgac agcaaacgtg ccttggtggt tgttccagat
     7501 aacaagcttt ctcttgccat tggtcgtcgt ggacaaaacg tgcgcttggc ggctcacttg
     7561 actggttacc gtatcgatat caagtctgct agcgaatttg aagccatgga agacgctgct
     7621 tcagtagagt tggaagtaga aaacgatact gtagaagaat aaaagctgct agaggaggga
     7681 aagatgaaaa caagaaaaat ccctttgcgc aagtctgttg tgtctaacga agtcattgat
     7741 aagcgtgatt tgctccgcat tgtcaagaac aaggaaggac aagtctttat tgatcctacg
     7801 ggcaaggcca atggccgcgg cgcttatatc aaactagaca atgcagaagc cctagaggcg
     7861 aaaaagaaga aggtctttaa ccgcagcttt agcatggaag tggaagaaag cttttatgac
     7921 gagttgatcg cttatgtgga tcacaaagtg aaaagaagag agttgggact tgaataagca
     7981 aaagataagt aatctcttgg ggcttgctca gcgagcaggg cgcatcatat cgggtgaaga
     8041 attggtggtc aaggccattc aagacggcaa ggccaagttg gtctttctag ctcatgatgc
     8101 tggacccaat ctgaccaaga agattcaaga taaaagtcat tattatcaag tagaaattgt
     8161 aaccgtgttt tcaacactgg aattaagcat agcagtcggg aaatcgagaa aggttttggc
     8221 tgtaacagat gctggattta caaagaaaat gaggtctctt atggaataga agaggaggac
     8281 atgatttgtc taagaaaaga ttgtacgaaa tcgcaaaaga acttggaaaa gaaagtaaag
     8341 aagttgtagc gcgtgcaaaa gagttgggct tggatgtgaa aagccactca tcaagtgtgg
     8401 aagaagctgt cgctgcaaaa attgctgcca gctttaagcc tgcagctgct ccgaaagtag
     8461 aagcaaaacc tgcagcacca aaagtaagtg cagaaaagaa agccgaaaaa tctgagccag
     8521 ctaaaccagc tgtagctaag gaagaggcaa aaccggctga gccagttgct ccgaaaacag
     8581 aaaaagtagc agtgaaaccg caaagtcgta atttcaaggc tgagcgtgaa gcccgtgcta
     8641 aagagcaggc agaacgacgc aagcaaaata agggcaataa ccgtgaccaa caacaaaacg
     8701 gaaaccgtca gaaaaacgac ggccgtaatg gtggaaaaca aggtcaaagc aaccgcgaca
     8761 atcgtcgctt taatgaccaa gctaagaagc agcaaggtca gcaaaaacgt agaaatgagc
     8821 gccgtcagca agaggataaa cgttcaaatc aagcggctcc acgtattgac tttaaagccc
     8881 gtgcagcagc cctaaaagca gagcaaaatg cagagtacgc tcgttcaagt gaggaacgct
     8941 tcaagcagta tcaggctgct aaagaagcct tggctcaagc taacaaacgc aaggaaccag
     9001 aggaaatctt tgaagaagcg gctaagttag ctgaacaagc acagcaagtt caagcagtgg
     9061 ttgaagtcgt ccctgagaaa aaagaacctg cagtggatac acgtcgtaaa aaacaagctc
     9121 gaccagacaa aaatcgtgac gattatgatc atgaagaaga tggtcctaga aaacaacaaa
     9181 agaatcgaag tagtcaaaat caagtgagaa atcaaaagaa tagtaactgg aataacaaca
     9241 aaaagaacaa aaaaggcaat aacaagaaca accgtaatca gactccaaaa cctgttacgg
     9301 agcgtaaatt ccatgaattg ccaacagaat ttgaatatac agatggtatg accgttgcgg
     9361 aaatcgcaaa acgtatcaaa cgtgaaccag ctgaaatcgt taagaaactt ttcatgatgg
     9421 gtgtcatggc cacacaaaac caatccttgg atggggaaac aattgaactc ctcatggtgg
     9481 attacggtat cgaagccaaa caaaaggttg aagtggataa tgctgacatc gaacgtttct
     9541 ttgtcgaaga tggttatctc aatgaagatg aattggttga gcgtccacca gttgttacta
     9601 tcatgggaca cgttgaccac ggtaaaacaa cccttttgga tactcttcgt aactcacgtg
     9661 ttgcgacagg tgaagcaggt ggtattactc agcatatcgg tgcctaccaa atcgtggaaa
     9721 atggtaagaa gattaccttc cttgatacac caggacacgc ggcctttaca tcaatgcgtg
     9781 cgcgtggtgc ttctgttacc gatattacga tcttggtcgt agcggcagat gacggggtta
     9841 tgcctcagac tattgaagcc atcaaccact caaaagcagc taacgttcca atcatcgtag
     9901 ccattaacaa gattgataaa ccaggtgcta acccagaacg cgttatcggt gaattggcag
     9961 agcatggtgt gatgtcaacc gcttggggtg gagattctga atttgttgaa atctcagcta
    10021 aattcaacca aaatatcgaa gaattgttgg aaacagtcct tcttgtagct gaaatccaag
    10081 aactcaaggc agacccaaca gtgcgtgcaa tcggtacggt tatcgaagcg cgcttggata
    10141 aaggaaaagg tgcggtcgca acccttcttg tacaacaagg taccttgaat gttcaagacc
    10201 caatcgttgt cggaaatacc ttcggtcgtg tccgtgctat gaccaacgac cttggtcgtc
    10261 gtgttaaagt tgctggacca tcaacaccag tctctatcac aggtttgaac gaagcaccga
    10321 tggcgggtga ccactttgcc gtttacgagg atgaaaaatc tgcgcgtgca gcaggtgaag
    10381 agcgtgccaa acgtgccctc atgaaacaac gtcaagctac ccaacgtgtt agccttgaaa
    10441 acctctttga tacccttaaa gctggggaac tcaaatctgt taatgttatc atcaaggctg
    10501 atgtacaagg ttctgttgaa gccctttctg cctcacttca aaagattgac gtggaaggtg
    10561 tcaaagtgac tatcgtccac tcagcggtcg gtgctatcaa cgaatcagac gtgacccttg
    10621 ccgaagcttc aaatgccttt atcgttggtt tcaacgtacg ccctacacca caagctcgtc
    10681 aacaagcaga agctgacgat gtggaaatcc gtcttcacag cattatctac aaggttatcg
    10741 aagagatgga agaagctatg aaagggatgc ttgatccaga atttgaagaa aaagttattg
    10801 gtgaagcggt tatccgtgaa accttcaagg tgtctaaagt gggaactatc ggtggattta
    10861 tggttatcaa cggtaaggtt gcccgtgact ctaaagtccg tgttatccgt gatggtgtcg
    10921 ttatctatga tggtgaactc gcaagcttga aacactataa agacgacgtt aaggaagtta
    10981 caaacggccg tgaaggtgga ttgatgatcg acggctacaa tgatattaag atggatgatg
    11041 tgattgaggc gtatgtcatg gaagaaatca agagataaga ttttttgctc ctttcttagg
    11101 tggtgaggga cgcaagcaaa ccgatggttt cattgcttat ttttgagcct agggtctcaa
    11161 aaatcccctg tgatgggact gataaatcag ttccatcact ttcaccacgg cgaaagaagc
    11221 agatgacttc aaattgaact tcgtttcaat ttaaactgaa aatcaagaag tttaaaatag
    11281 ctaggtctgc tggcctagct tttggttcaa agtagagaaa ggaatatcat ggcaaatcat
    11341 ttccgtacag atcgtgtggg catggaaatc aagcgtgaag tcaatgagat tttgcaaaag
    11401 aaagtccgtg atccacgtgt ccaaggtgtg accatcacag atgttcagat gctgggtgac
    11461 ttgtctgttg ccaaggttta ttacaccatt ttgagtaacc ttgcttcgga taaccaaaaa
    11521 gcccaaatcg ggcttgaaaa agcaactggt accatcaaac gtgaacttgg tcgcaatttg
    11581 aaattgtaca aaatcccaga tttgaccttc gtcaaagacg agtccatcga gtatggaaac
    11641 aagattgacg agatgctacg caatctggat aagaactaaa gaagaggggt tgcccctctt
    11701 tttcggctct ttgtcaactg tagtgggttg aagaaaagct aagctcgaga aaggacaaat
    11761 ttcgtccttt cttttttgat attcagggcg ataaaaatcc gttttttgaa gttttcaaag
    11821 ttccgaaaac caaaggcatt gcgcttgata agtttgatga gattattggt cgcttccagt
    11881 ttggcattag aatagtgtag ttgaagggcg ttgacaatct tttctttatc tttgaggaag
    11941 gttttaaaga cagtctgaaa aataggatga acctgcttaa gattgtcctc aataagtccg
    12001 aaaaatttct ctggttcctt attctggaag tgaaaaagca agagttgata gagttgatag
    12061 tggtgtttca agtcttccga ataactcaaa agcttgttta aaatctcttt attggttaag
    12121 tgcatacgaa aagtaggacg ataaaaacgt ttatcactca gtttacggct atcctgttga
    12181 atgagtttcc agtagcgctt gatagccttg tattcatggg attttcgatg aaactgattc
    12241 atgatttgga cacgcacacg actcatagca cggctaagat gttgtacaat atgaaagcga
    12301 tcaagaacga ttttagcatt cgggagtgaa acagtctggg agactgtttc agcctgagcc
    12361 tagaaatttg aaagcgaagc tgtttagcca agtcatagta agggctaaac atatccatag
    12421 taatgatttt gacgcgacat cggacggctc tatcatattt aagaaagtga tttcgaatga
    12481 tagcttgtgt tcttccctca agaacagtga tgatattgag attgttaaaa tcttgcgcaa
    12541 tgaagctcat ctttcccttt gtaaaagcat actcatccca agacataatc tcaggaagac
    12601 gcgaaaaatc atgctcaaag tgaaagtcat tgagcttgcg aatgacagtt gaagttgaaa
    12661 tggccagctg atg
//
LOCUS       DAVBEO010000057        12573 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 009
            SAMEA1678075-rid20185393.denovo.057, whole genome shotgun sequence.
ACCESSION   DAVBEO010000057 DAVBEO010000000
VERSION     DAVBEO010000057.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678075
            Sequence Read Archive: ERR226392
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12573)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12573)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980207.1
            Genome Coverage       :: 150x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:50:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 72 of 147
            Pseudo Genes (incomplete)         :: 72 of 147
            Pseudo Genes (internal stop)      :: 42 of 147
            Pseudo Genes (multiple problems)  :: 32 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12573
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678075-rid20185393.denovo.057"
                     /strain="KS 009"
                     /db_xref="taxon:1313"
     gene            complement(251..433)
                     /locus_tag="VQ543_001805"
     CDS             complement(251..433)
                     /locus_tag="VQ543_001805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000268343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2612480.1"
                     /translation="MAVIFKNVLIEEKTEEEKQHILSILNGEYDLSDDVSCRLRRLNE
                     ESKRLEVFVKETNSLV"
     gene            complement(649..1881)
                     /locus_tag="VQ543_001806"
     CDS             complement(649..1881)
                     /locus_tag="VQ543_001806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide sugar dehydrogenase"
                     /protein_id="HET2612481.1"
                     /translation="MKIAVAGTGYVGLSIAILLAQHHQVVAVDIIPEKVELINKKKSP
                     IQDDYIEKYLAEKELNLVATLNAEEAYENADFIVIAAPTNYDPKKNFFDTSSVEAVIE
                     AVMKYNPDAIIIIKSTVPVGYTKSVRRKFLTDNIMFSPEFLRESKALYDNLYPSRIII
                     GTDKDDKDLVKSAEIFVKMLQEGAVKENIETLYMDFTEAEAVKLFANTYLALRVSYFN
                     ELDTYSEMKGLDTQAIIDGVCLDPRIGSHYNNPSFGYGGYCLPKDTKQLLANYSDVPQ
                     EMITAIVQSNRTRKDYIADRILDLAGSYVGNDFYKPDKEKEIVVGIYRLTMKSNSDNF
                     RQSSIQGIMKRLKAKGVTIIIYEPTLESGTTFYGSQVVNDFEIFKKSSQVIVANRFDE
                     TLEDVRGKVYTRDIFKRD"
     gene            complement(1910..2980)
                     /gene="gla"
                     /locus_tag="VQ543_001807"
     CDS             complement(1910..2980)
                     /gene="gla"
                     /locus_tag="VQ543_001807"
                     /EC_number="5.1.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001214397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucuronate 4-epimerase Gla"
                     /protein_id="HET2612482.1"
                     /translation="MRGKTILITGVAGFIGSNLVRKLLELEGTMTIIGLDNLNDYYDI
                     ALKDYRLLQLNKLIQDYPEKNWIFIKGDIADKMLINKIFKSYHPQIVVNLAAQAGVRY
                     SITNPDVYIESNIVGFHNVLEACRHSYEIYDGGVEHLVYASSSSVYGGNKKIPFATED
                     KVDNPISLYAATKKTNELQAYAYSKIYNIPSTGLRFFTVYGPAGRPDMAYFGFTDKLR
                     SGSDIEIYNHGNCKRDFTYIDDIVEGIVRVMQSAPKKLVGSDNLPLAPYKVYNIGNSK
                     PENLLDFVDVLQQELIKAGVLPENYDFDSHKKLVPMQPGDVPVTYADTSDLERDFGFK
                     PKTSLREGLRKFAEWYKDYYNV"
     gene            complement(3048..4217)
                     /locus_tag="VQ543_001808"
     CDS             complement(3048..4217)
                     /locus_tag="VQ543_001808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide flippase family protein"
                     /protein_id="HET2612483.1"
                     /translation="MRLSKKYWFALTSKFLLILLTLLSSIIINRGLGVEKKGDYAYVM
                     NLVEIFYILGGVGLGQAYSTFKRNHSNEYQNKFVFLTFIQGLLFGIIGLIIVLADVPI
                     DYGGVIIVLSSLSIMRTNLTMIAVIENSIKRNKIVLGVSVVYSVMLVLLLLFHLVSIE
                     MVFLVYAINEFLRIILFLYYYNMFPVFEHISIKEFFTIYKFGFLSMILTLLITFNYSI
                     DIIMLKQMSSSYNVGIYSVAVTFSNMFLMVPDSFKEILFGDSAKRTFEKNKAINAIKV
                     SFLFMILLIIGFLSFGEFAITLLYGSSYIKAFPITLVIFLGSLSMIFFKILQPIYISQ
                     GKQSVAIKILSVSALINISLNWYLIPNYQITGAAIASAISYTVCGLFFIIDYLRN"
     gene            complement(4403..5707)
                     /locus_tag="VQ543_001809"
     CDS             complement(4403..5707)
                     /locus_tag="VQ543_001809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000672721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide repeat unit polymerase"
                     /protein_id="HET2612484.1"
                     /translation="MKFSLQSNDIKNKIILLVGVVFSGTLILCSENNDVTIPLFSMIF
                     LSFMAMIIVKFNIFHPYVWYSSFFTIYSISYPLLYRMEYINYGYTKDLIFMQWLALAT
                     LLLTLPSKAIVLSERKINLNNNNYLLFLNNMNTFITTVAIIYLLGSGFRNKGEIYSGA
                     NIVIMLVFSLVYFMILIHTYQLFIQLSTKKWRLLNCNTNTAIVICLFSIVTGERDYMF
                     TLFILDVIILFYFHKIKRFYLVMLVPLAALLIPLSAVFKYTLLSGQVSSINTNNIWFD
                     LLDGEFVSASRNLQILILHNMGNYFEGRSFFNDIVRIFYNTGYSNQTWFMDTFFPNVH
                     STKYGFTLVGEGYVNGGYFGIVMIFMLTGFLMRFLYINAQRNIYGMLIYLYMIPIFIY
                     STRADFANILSPLLKYAILGTLVIVFINRMVLISPLDEMGGE"
     gene            complement(5824..6978)
                     /locus_tag="VQ543_001810"
     CDS             complement(5824..6978)
                     /locus_tag="VQ543_001810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000862350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HET2612485.1"
                     /translation="MKVFIATEFRCTIYKNEIYLKPKAYFIYERYAKAFGEIVLCSRY
                     EKVESYPEGYHKANFINKFIPIEGLHQVLFGQNKNKIIEGMIDSDLIVVRIPSIIGSK
                     TADYALKIGKPYLTEIMGDAWDSYWYHSLKGKLLAPYIYAKTKSIVKNANYCIYVTEK
                     YLQDRYPNIKSNIVASNVNITSVENRSLKSRLYKLKKFNPQKISIMTTASVNVRAKGH
                     RFVLEAMKRLEIQGILLDYYLAGDGDQSFLKKKAEELGVANRIHFLGELTTSQIYEYL
                     DKVDLYIQPSLQEGLPRAVIEAMSRACPCIGSNKAGIPELLGPHCLFTPSSSQAIAGS
                     IIDFISMDKEKMVIKQFEFSKKFLSSVLNKRRSDYFAQIRRELNNSDGLD"
     gene            complement(6975..7526)
                     /locus_tag="VQ543_001811"
     CDS             complement(6975..7526)
                     /locus_tag="VQ543_001811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001079795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase"
                     /protein_id="HET2612486.1"
                     /translation="MNRIIKNIVGLLRANICLILLKVCRNKDLTFHYFLKFGKNVTVE
                     QESNAKLILGKKIRVNAGGVLKVRKGAKLKISDDVFLSNNCMIACRKYIDIKSGVKCG
                     PGVLIYDHDYDVSVPGGLKAKKFKTAPVMIGENVWIGANSIVLKGVSIGENSVVAAGS
                     VVTKDIPADTIFIQKRLSREMKL"
     gene            complement(7519..8655)
                     /locus_tag="VQ543_001812"
     CDS             complement(7519..8655)
                     /locus_tag="VQ543_001812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001053205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HET2612487.1"
                     /translation="MNLQKKKIMLITNHDDDIYCFRKEVIESLVEYGYEVLVSCPYGD
                     KIELMKSIQFEYEDITIDRRGINPLKDIRLFLSYIRLLRKYRPDVVLTYTVKPNVYAS
                     LAATILGIKYINNVTGLGSVLTMGSCVRSLVLLLFRISFRKSNCVFFQNEYNMKMLKT
                     LGLILGDSKLIPGSGVNIEKYPVQQYPNGGNGIQGETIVFNFIGRILKEKGIDTYLAA
                     AQIIKSRYPKTEFNIIGFIEPTESNYELKICDLEKKGIVYYLGQQKDVIPHITRSHAI
                     IHPSVYGEGMSNVLLENASSGRVLITTDNPGCKEIVKDRETGYIFQGGNVEELVSILE
                     VFLGLENEKRKEMGLQGRMYIEQYFSRQIIIDAYLDKIKGALDE"
     gene            complement(8796..9461)
                     /gene="cpsD"
                     /locus_tag="VQ543_001813"
     CDS             complement(8796..9461)
                     /gene="cpsD"
                     /locus_tag="VQ543_001813"
                     /EC_number="2.7.10.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001845065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis tyrosine autokinase
                     CpsD"
                     /protein_id="HET2612488.1"
                     /translation="MPTLEIAQKKLEFIKKAEEYYNTLCTNIQLSGDKLKVISVTSVN
                     PGEGKTTTSVNIAMSFARAGYKTLLFDGDIRNSVMSGFFKSREKITGLTEFLSGTADL
                     SHGLCDTNIENLFVVQSGSVSPNPTALLQSKNFNDMIETLRKYFDYIIVDTPPIGIVI
                     DAAIITQKCDASILITATGEANKRDVQKAKQQLEQTGELFLGVVLNKLDISVDKYGVY
                     GRK"
     gene            complement(9471..10163)
                     /gene="cpsC"
                     /locus_tag="VQ543_001814"
     CDS             complement(9471..10163)
                     /gene="cpsC"
                     /locus_tag="VQ543_001814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000664160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular polysaccharide biosynthesis protein
                     CpsC"
                     /protein_id="HET2612489.1"
                     /translation="MKEQNTLEIDVLQLFRALWKRKLVILLVAIITSSVAFAYSTFVI
                     KPEFTSTTRIYLVNRNQGEKPGLTNQDLQAGAYLVKDYREIVLSQDVLEEVISDLKLD
                     LMPKGLANKIKVTVPVDTRIVSVSVSDRVPEEASRIANSLREVAAQKIISITRVSDVT
                     TLEEARPAISPSSPNIKRNTLIGFLAGVIGTSVIVLLLELLDTRVKRPEDIENALQMT
                     LLGVVPNLGKLK"
     gene            complement(10172..10903)
                     /locus_tag="VQ543_001815"
     CDS             complement(10172..10903)
                     /locus_tag="VQ543_001815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-protein phosphatase CpsB"
                     /protein_id="HET2612490.1"
                     /translation="MIDIHSHIVFDVDDGPKSREESKALLAESYRQGVRTIVSTSHRR
                     KGMFETPEEKIAENFLQVREIAKEVADDLVIAYGAEIYYTLDALEKLEKKEIPTLNDS
                     RYALIEFSMHTSYRQIHTGLSNILMLGITPVIAHIERYDALENNEKRVRELIDMGCYT
                     QINSYHVSKPKFFGEKYKFMKKRARYFLERDLVHVVASDMHNLDSRPPYMQQAYDIIA
                     KKYGAKKAKELFVDNPRKIIMDQLI"
     gene            complement(10905..12350)
                     /locus_tag="VQ543_001816"
     CDS             complement(10905..12350)
                     /locus_tag="VQ543_001816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000091082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HET2612491.1"
                     /translation="MSRRFKKSRSQKVKRSVNIVLLTIYLLLICFLLFLIFKYNILAF
                     RYLNLVVTALVLLVALVGLLLIIYKKAEKFTIFLLLFSILVSSVSLFAVQQFVGLTNR
                     LNATSNYSEYSISVAVLADSKIENVTQLTSVTAPTGTDNENIQKLLADIKSSQNTDLT
                     VNQSSSYLAAYKSLIAGETKAIVLNSVFENIIESEYPDYASKIKKIYTKGFTKKVEAP
                     KTSKNQSFNIYVSGIDTYGPISSVSRSDVNILMTVNRDTKKILLTTTPRDAYVPIADS
                     GNNQKDKLTHAGIYGVDSSIHTLENLYGVDINYYVRLNFTSFLKMIDLLGGVDVHNDQ
                     EFSALHGKFHFPVGNVHLDSEQALGFVRERYSLTDGDRDRGRNQQKVIVAIIQKLTST
                     EVLKNYSSILQGLQDSLQTNIPIETMIDLVNTQLESGGNYKVNSQDLKGTGRMDLPSY
                     AMPDSNLYVMEIDDSSLTVVKAAIQDVMEGR"
BASE COUNT         4237 a         2433 c         1656 g         4247 t
ORIGIN      
        1 aattcactta cttcatatta catttagcat gaaatgaaat aagcgaattc tactttgttt
       61 gcatacaatt aaaaatcaat tcctaaggat gttttaaata actgtgtaaa aggcataatt
      121 tcaccatttc ttagtttttc aatgctaaat tacatagtaa ctggagagct attagaaatc
      181 tctaacttcc tcatagttaa aaaatgacaa tgagatactt attgatttca attcattaac
      241 agaatacgaa ctagacaagt gagttcgtct ccttaacaaa cacttccaag cgtttacttt
      301 cctcattcag tcgtcgtaat ctacaactta catcatcaga taagtcatac tcaccattta
      361 gaatagatag aatatgttgt ttttcttctt cagtcttctc ttcaataagc acatttttaa
      421 aaattactgc cattatcagc acctcacttc gaaggaatat atgcaactat atcctattaa
      481 gtcaatctct actgacaaaa gaagtatatt tacttcacta agtgcgagcg agaatataga
      541 aatatcttta ttgttttaga tgagttgtcg ctatcctcca gctagttttt aactattcta
      601 tcattcaaat gatatagatt attagggact agaaatatac aaattgattt aatctctctt
      661 aaaaatatcc ctagtataaa ctttacccct cacatcttct aaagtctcat caaaacgatt
      721 tgcaacaatc acttgactag atttcttaaa tatttcaaaa tcattaacta cttgactacc
      781 atagaaagta gtaccacttt caagagttgg ttcgtaaata ataatagtaa caccttttgc
      841 tttcaaacgc ttcataatac cttgaataga agattgtcta aaattatctg aattactttt
      901 cattgttaaa cgataaattc ctacaacaat ctctttttct ttatctggtt tatagaaatc
      961 attgcctaca taagatccag caagatctaa aatacgatct gcaatataat cttttcttgt
     1021 ccgattactt tgtactatag ctgttatcat ttcttgtgga acgtcagaat aatttgcaag
     1081 aagttgcttg gtatctttag gaagacagta acccccataa ccaaaagaag gattattgta
     1141 gtgagaacct attctcggat ctaaacaaac tccatcaata atcgcttgag tatctagtcc
     1201 tttcatctca gaataagtat ctaactcgtt aaaataggaa acccggaggg caagataggt
     1261 attagcaaaa agttttactg cttcagcttc tgtaaaatcc atatacaatg tttcaatatt
     1321 ttctttcact gcaccttcct gaagcatttt tacaaaaatt tcagcagact ttaccaaatc
     1381 tttatcatct ttatctgtac ctataataat tcgactcgga tataggttat catataacgc
     1441 ttttgactcc cgtaaaaact caggactaaa cataatattg tctgtaagaa atttcctccg
     1501 tactgacttt gtatatccaa caggaacagt acttttaatt attataattg catcaggatt
     1561 atatttcata actgcttcaa tgacagcctc gactgaagat gtatcgaaaa aatttttttt
     1621 cggatcataa ttagttggag ccgcaataac tataaaatcc gcattctcat atgcttcctc
     1681 tgcattcaat gtagctacga gattcaattc tttttccgcg agatattttt ctatataatc
     1741 gtcttggata ggggacttct ttttattgat taactcaact ttctcaggaa tgatatctac
     1801 ggcaacaact tgatgatgtt gagccagtaa gattgcaata gataatccaa catatcctgt
     1861 acctgctact gctattttca taattttttc ctttctcaaa acactctcgt tatacattat
     1921 agtagtcttt ataccactct gcaaactttc tcaaaccttc tcgtaaagaa gtttttggtt
     1981 taaaaccaaa atctctctct aaatcacttg tatctgcata agtaacagga acatcgcctg
     2041 gttgcatagg aactaatttt ttatgactat caaaatcata attttccggc aaaactcctg
     2101 ccttgattag ctcctgttga agaacatcca caaaatctaa caaattttcg ggtttactat
     2161 tcccaatatt gtacacttta tatggggcta acggtaaatt atcagatccc actagtttct
     2221 tcggagctga ttgcatgacc cttactatcc cctcaacgat atcatctata taagtaaaat
     2281 ctcgtttaca attaccatga ttataaatct caatatcgga accacttcgc aatttatctg
     2341 taaatccaaa ataggccata tctgggcgcc cagcaggacc ataaactgta aaaaagcgta
     2401 agcctgtcga aggaatattg taaatctttg aataagcata cgcttgaagt tcatttgttt
     2461 ttttagtcgc agcatatagt gaaataggat tgtctacctt atcttctgtt gcaaacggga
     2521 tttttttatt tccaccatat accgatgagg acgatgcata aactaagtgt tccacaccac
     2581 catcatatat ctcatacgaa tgacgacaag cttccaacac attatgaaag ccaacgatat
     2641 tactttctat atatacatct ggatttgtaa tggagtagcg tactcctgcc tgggcagcta
     2701 gattaacaac aatctgagga tgataactct taaaaatctt attaataagc attttatctg
     2761 caatatcacc cttgataaat atccagtttt tttctggata atcctgaatt agcttattaa
     2821 gttgaagcaa tcgataatct ttaagtgcaa tatcatagta atcattcaaa ttgtccaaac
     2881 caatgattgt catcgttcct tctaattcca ataatttcct aaccagattt gatccaataa
     2941 aaccagctac tcctgtaatt agaattgttt ttcctctcat atcataatac ctcttgttat
     3001 ttttatattt tcgtccacta atacacattc tttaacaact attataatca atttctaaga
     3061 taatctataa taaaaaacaa accacataca gtataagaga ttgctgatgc tatcgcagct
     3121 cctgtaattt ggtagttagg aattaagtac cagtttaaac ttatatttat caaagccgac
     3181 acagataaaa tttttatagc tacactctgt ttaccctgag atatataaat tggttgtaaa
     3241 attttaaaga aaatcatcga taagcttcct aaaaaaatga ctaatgttat aggaaatgcc
     3301 tttatataac tggaaccata aaggagcgta atcgcaaatt ctccaaaaga aagaaatcca
     3361 ataattaata aaatcataaa tagaaatgat acttttattg catttattgc tttatttttc
     3421 tcaaaagttc ttttagccga atcaccaaat aaaatctctt taaatgagtc tggaaccatc
     3481 aaaaacatat tagaaaacgt aactgcgaca ctgtatatac ctacattata actactagac
     3541 atttgcttca acattatgat atcaatacta taattaaatg taattaatag agtaagaatc
     3601 atagaaagaa atccaaactt atatatagtg aaaaattctt taatactaat atgttcaaaa
     3661 actgggaaca tattgtaata gtataaaaat aaaatgatac gtaaaaattc attaatagca
     3721 tataccaaaa ataccatctc tatagaaact aaatgaaata gtaacaacaa tactagcata
     3781 acggaatata ctacgcttac tcctaataca atcttattcc tctttatact attttctatt
     3841 actgcaatca tagtaagatt tgttctcata atagatagac tggacaaaac tattattacc
     3901 ccaccataat ctatcggaac atcagctaaa actattatta aacctattat tccaaacaat
     3961 aatccttgaa taaaagttaa aaaaacaaat ttattctgat actcattaga atgattcctt
     4021 ttaaaggtcg agtaagcctg acctaaacca actccaccta aaatataaaa aatttctact
     4081 aagttcatta cataggcata atctcctttt ttttcaacac ctaatcccct attaattata
     4141 attgaggata aaagtgttaa taagattaac aaaaatttac tcgttaaagc aaaccaatat
     4201 ttcttagata gtctcactta ttttctccgt atgttaaatt ttataacagt aaatttaaaa
     4261 ttatagtata ttgaaataga atatgaacaa aacgattagg gaatttaaag taatttataa
     4321 aaattcttta gaagctgcat tgtactactc caacttcaaa ccactatagt atcaaaaagt
     4381 ataccccacc tttttaaata aactactcac cacccatttc atccaatggt gatatcaaca
     4441 ccattctatt gataaaaaca ataaccaatg ttcccaatat agcatattta agtaatggag
     4501 ataatatgtt agcaaaatca gcacgagtag aataaataaa aataggtatc atatacagat
     4561 atatcagcat cccgtatata tttctttgag cgtttatata aagaaatctc atcaaaaagc
     4621 ctgttagcat aaaaatcatt acaattccaa agtatcctcc attcacatat ccctctccca
     4681 caagagtaaa accatatttg gttgaatgta cgtttggaaa aaaggtgtcc ataaaccaag
     4741 tttgattaga ataccccgta ttataaaaaa ttcttactat gtcattaaaa aaagaacgac
     4801 cttcgaaata attgcccata ttatgtaata tcagaatctg taaattacga ctagctgata
     4861 caaactcacc atctagcaaa tcaaaccaaa tattatttgt atttatagat gaaacttgcc
     4921 cacttaataa agtatattta aaaactgcag ataacggaat cagtagtgcc gcaagcggaa
     4981 ctaacattac aagataaaaa cgttttattt tgtgaaagta aaataatata atcacatcaa
     5041 ggatgaataa agtaaacata taatctcttt cccctgtaac gatagagaag agacagataa
     5101 ctatcgctgt gttagtatta caatttagta gtctccattt tttagtactc aactgtataa
     5161 atagctgata tgtatgaatg agaatcataa aataaaccaa agaaaatact aacattatca
     5221 caatattggc acctgaatat atttcccctt tatttctaaa accacttcct aatagatata
     5281 taattgctac tgttgtgata aacgtattca tattattgag aaataataaa tagttattgt
     5341 tatttaggtt tattttcctt tcgcttaaca caatggcttt agaaggtaga gttaacaaca
     5401 aagttgccaa agccagccat tgcatgaaaa tcaaatcttt tgtataacca tagtttatat
     5461 actccattct atagagtagc gggtaagaaa tagaataaat agtaaagaag ctactatacc
     5521 acacataggg atgaaaaata ttaaatttca caattatcat tgccataaaa cttaaaaaaa
     5581 tcattgaaaa taatggaatt gtaacatcat tattttcact gcataaaatt aaagtccctg
     5641 aaaaaactac acctactaga agtattattt tattttttat atcatttgat tgtagactaa
     5701 acttcattta cttttttcct ttaactaata atttaaacgt aatgcgtatt caaaaatttg
     5761 attggctatg tagtcagttt ttatagcata tttaatatat cgaaacggat tttccatcgc
     5821 attttaatct aaaccatcag aattatttaa ttctcttcta atttgagcaa aatagtcact
     5881 tctgcgttta tttaatacac tcgaaagaaa tttttttgag aattcaaact gttttatcac
     5941 catcttttcc ttatccatac taataaaatc tataatagat cccgcaatcg cttgtgaaga
     6001 ggatggagta aatagacaat gtggccccag caactctgga attcctgctt tattagaccc
     6061 tatacaaggg caagcacggc tcatagcttc aattaccgca cgaggtaacc cttcttgtaa
     6121 acttggttgt atatataaat caactttatc caaatactca taaatttgtg atgtagtcaa
     6181 ttcccctaaa aaatggattc tattcgctac tcccaattcc tctgctttct tttttaagaa
     6241 actttgatca ccatcacctg ctaaataata atccaacaaa ataccttgta tttctaatct
     6301 cttcattgct tccaatacaa atctatggcc cttggctcgt acattcacag atgctgttgt
     6361 cattattgaa attttttgag gattaaattt tttcaactta taaagacggc tcttcaaaga
     6421 tctattctct acagaggtaa tattaacatt tgaagcaacg atattagatt taatattagg
     6481 atatctatct tgtaaatatt tttctgtcac gtatatgcaa taattagcgt tttttacaat
     6541 tgatttagtt ttggcgtata tatatggagc taataatttt ccctttaaac tatgatacca
     6601 gtaagaatcc caagcatccc ccattatttc tgtcagatac ggcttaccta tcttcaatgc
     6661 gtagtctgca gtttttgatc caattataga cggaatacga acaactatta agtcgctatc
     6721 aatcattcct tcaataatct tatttttatt ttgaccaaat agaacctgat gtagaccttc
     6781 tatagggata aatttattaa taaagttcgc tttatgatat ccttcagggt atgattccac
     6841 cttctcataa cgactacata gtacaatctc tccaaatgct ttagcatagc gctcataaat
     6901 aaaataagct ttcggtttta aatatatttc atttttatag attgtacatc taaattcagt
     6961 cgctataaat actttcataa tttcatctcc cttgataaac gtttctgaat aaatatagta
     7021 tcagctggaa tatcctttgt tacaacactt cctgctgcaa ccacactatt ctcaccaata
     7081 ctcactccct tcaagacaat gctgttagct ccaatccaaa cattttctcc aatcataact
     7141 ggggccgtct taaatttttt tgctttcaat ccacctggaa cactaacatc atagtcatga
     7201 tcatatataa gtactccagg accacatttt actccagatt taatatctat gtatttacga
     7261 caagctatca tacaattatt actcaaaaat acatcatcag aaatcttgag ttttgctcct
     7321 tttctaactt tcaatactcc cccggcgttt actctaatct tttttcctaa gattaattta
     7381 gcattagatt cctgttcgac agttacattc tttccaaatt ttaaaaaata atgaaaagta
     7441 agatccttgt ttcgacacac ttttaataat atcaagcaaa tatttgcacg aagtaaacca
     7501 acaatatttt ttataatcct attcatctaa agctcctttt attttatcta aataagcatc
     7561 tataataatt tgacgagaaa aatattgctc tatatacatt ctcccttgaa gtcccatctc
     7621 ttttcgtttt tcattttcta gacctaaaaa aacttccaat atagagacta gttcctcaac
     7681 atttccccct tgaaatatat agcctgtctc tctatcttta acaatttctt tgcaacctgg
     7741 attatctgtc gtaattaaaa cacgtcctga actagcgttt tctagtaata cattgctcat
     7801 tccttcacca tacacactgg gatggataat tgcatgggaa cgggtaatat gaggtatcac
     7861 atctttttgt tgtcccaaat aataaacgat tccttttttt tctaagtcac aaattttaag
     7921 ttcataatta ctctctgtcg gttctataaa gccaataata ttaaactctg ttttgggata
     7981 tcgactctta ataatttggg cagcagccag ataagtatct ataccttttt cttttaatat
     8041 cctaccaata aaattaaaaa cgattgtttc tccttgaatt ccatttccac catttggata
     8101 ctgttgcaca ggatactttt caatgttcac tcctgaccca ggtatcagct tagagtcacc
     8161 caaaatcaag ccaagagttt ttaacatttt catattatat tcattttgaa aaaaaacaca
     8221 atttgatttc ctaaaagaaa ttctaaacag taataacacc aggcttctta cacaagaacc
     8281 cattgttaag acactaccta aacctgttac gttatttata tattttattc ctaaaattgt
     8341 tgcagctagg ctagcatata catttggttt cacggtatat gtcaagacta catccggtct
     8401 atattttctc aataatctta tataactaag aaatagacga atatctttta aagggtttat
     8461 tcctcttcta tcaatagtaa tatcttcata ctcaaattga atagacttca tcaactctat
     8521 cttatctcca taaggacatg acactagcac ttcataccca tactcaacta gtgactctat
     8581 aacttctttt cgaaaacaat agatatcatc gtcatgatta gttattaaca taattttttt
     8641 cttttgtaaa ttcatcaaaa taatcttcct aaaatataat taaccgctac tccattatcc
     8701 tttacaacta tcattttaaa aatagtaatt ttctataagt aattgtttcc aaattgtgac
     8761 actttaaaat tctatacaca tatagaactt acaaactatt tacgaccgta aactccatac
     8821 ttatcaaccg agatatccaa tttatttaaa acaactccca ggaacagttc ccctgtttgt
     8881 tctaattgtt gtttcgcttt ttggacatca cgtttattcg cctcacctgt tgctgttatc
     8941 aagatggacg catcacactt ttgagtgata attgccgcat caataacaat tccaataggt
     9001 ggtgtatcaa caatgatata atcaaaatat ttacgcaatg tttcaatcat atcattaaaa
     9061 tttttacttt gtaacaaggc tgtagggttt ggtgatacag atcccgattg aactacaaat
     9121 aaattttcaa tatttgtatc acataaaccg tgagataaat cagctgtccc agataaaaat
     9181 tctgttagcc ctgtaatttt ttcacgagat ttaaaaaatc ctgacataac tgaatttcga
     9241 atatcgccat cgaacaaaag agttttatag cctgcacgcg caaatgacat tgctatattt
     9301 acggaagtag ttgtttttcc ttcccccgga ttaacagaag taacggaaat tacttttagt
     9361 ttatctccgc tcaactgtat atttgtacac aaggtattgt aatattcttc tgccttctta
     9421 atgaactcca gttttttttg tgctatttct aatgtcggca tctctctctc ctatttcaac
     9481 ttacccaagt ttggtacaac tcccaaaagt gtcatctgca gtgcattttc gatatcttcc
     9541 ggacgtttca cacgagtgtc caaaagttca agaagaagaa ctataacact agttccaatc
     9601 acccctgcca aaaaaccaat tagtgtattg cgtttaatat ttggcgaaga cggtgatatc
     9661 gccggtcttg cctcctccag tgttgtcaca tcagaaacac gagtaatact gataattttt
     9721 tgagcagcta cttctcttaa agagttagcg atacggcttg cctcttcagg aactcgatca
     9781 ctaactgaaa cagagacaat acgggtatca actggtactg ttactttaat tttattagcc
     9841 aaaccttttg gcatcaaatc tagtttcaaa tcagaaataa cttcctccaa aacatcctgc
     9901 gataggacaa tttcacgata gtctttaacc aagtatgctc ctgcctgcaa gtcttgattg
     9961 gttaaaccag gcttctctcc ctgattacgg ttaactagat aaatccgagt cgtactagta
    10021 aactcaggtt tgataacaaa agtactgtag gcaaaagcaa ctgaagaagt tataattgcc
    10081 actaataaaa tgaccaactt tcttttccat aaagctctga atagttgcaa tacatcgatt
    10141 tccaaagtgt tttgttcctt catattttct cctaaattaa ttgatccatt ataatttttc
    10201 tgggattatc tacaaaaagt tctttcgctt ttttcgctcc atatttctta gcaatgatat
    10261 catatgcctg ttgcatatat ggaggtctac tgtctaaatt gtgcatgtca cttgcaacta
    10321 catgaactaa atcacgttcc aaaaaatacc gagctctctt tttcatgaat ttatattttt
    10381 caccaaagaa cttaggtttt gaaacatgat aactatttat ctgagtatag caccccatat
    10441 caatcagttc acgaacacgt ttttcgttat tctctaaagc atcataacgt tcaatatgag
    10501 caattactgg cgtgattccc aacatcaaaa tattgctcaa tcccgtatga atctgacgat
    10561 aggaagtatg catgctaaac tcaatcaagg cataacgact atcattaagg gtaggaattt
    10621 cttttttttc tagcttttct agagcatcca gagtatagta tatctctgcg ccataagcaa
    10681 tgactaaatc atctgctact tcttttgcaa tttcccgaac ctgaagaaag ttttctgcta
    10741 tcttctcttc cggagtttca aacatgccct tgcgacggtg agaggtagag acaatggttc
    10801 tcaccccctg cctgtaggat tctgccaaga gagccttgct ttcctctctt gacttgggac
    10861 catcatctac atcaaagacg atgtgcgaat ggatgtctat cattttatct accctccatc
    10921 acatcctgta tagctgcttt aactacagtt aaactactat catctatttc catcacatag
    10981 aggttactgt ctggcattgc ataagaagga agatccatcc gacctgtccc ttttaaatct
    11041 tgagaattta ctttataatt ccctccactt tccaactgag tattcactaa atctatcata
    11101 gtctcaatcg gtatatttgt ttgaagagaa tcctgcaatc cttgaagaat actactatag
    11161 tttttcaaaa cctctgtaga agttaacttc tgaataattg ctacaatgac cttttgttgg
    11221 ttgcgaccac ggtcacggtc tccatcggtt agtgagtagc gttcacgtac aaaacctaaa
    11281 gcttgctcag agtctagatg gacattccct actgggaaat ggaacttccc atgtagagct
    11341 gaaaactctt gatcattatg aacatctacc cctcccaata agtcaatcat tttcaagaaa
    11401 gaagtgaagt tcaatcgcac atagtaattg atatccactc catagagatt ttctaaggtg
    11461 tgaatggacg aatcaactcc ataaatgccc gcatgggtta atttatcttt ttgattattt
    11521 ccactatctg cgattggtac ataggcatca cgtggcgttg tggtcaagag gattttcttg
    11581 gtatctcgat tgacagtcat taggatattg acatctgatc gcgacaccga actaatagga
    11641 ccataggtgt caattccact aacatagata ttgaaagact gattcttaga cgtcttagga
    11701 gcctctactt ttttagtgaa tcccttggta taaatctttt ttatcttcga tgcgtagtct
    11761 ggatactctg actcgatgat attttcaaag acactattta ggacaatggc cttagtctcc
    11821 cctgcaatca aactcttgta agctgccaag taagacgaac tctggttgac cgtcaaatcg
    11881 gtattctgac ttgacttgat atcagctagt agtttttgaa tattttcatt atcagtccca
    11941 gtcggtgctg tcacactcgt cagttgcgta acattttcga tcttactatc tgctaaaaca
    12001 gcgacactga ttgaatattc tgagtaatta gaagtcgcat ttaaacgatt ggtcagtcca
    12061 acaaactgct gtactgcaaa gagcgacact gagctgacaa ggatagagaa cagcaacaga
    12121 aaaatagtaa acttttcagc ttttttatag ataatcaaga gtagccctac caaggcaact
    12181 agtaggacta acgcagttac cactaggtta agatatctaa aagcaaggat attgtactta
    12241 aagattaaga acaataaaaa acaaattaac aataaataaa tagtcagcaa aacgatatta
    12301 acacttcgct tcactttctg tgaacgtgat tttttaaaac gtctactcat gattaacacc
    12361 tataccttga acatcataca attatatcac ttttttacgg taatgtctac acctttattt
    12421 tcactatctg catctttaag tatcttagta gacttcccgc gaaccaaaaa tatagtaaaa
    12481 tgaaataaga ataggacaaa tcaatcagga cagtcaaatc gatttctaac aatgttttag
    12541 aatcagatgt gtactattct agtttcaata taa
//
LOCUS       DAVBEO010000058        12480 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 009
            SAMEA1678075-rid20185393.denovo.058, whole genome shotgun sequence.
ACCESSION   DAVBEO010000058 DAVBEO010000000
VERSION     DAVBEO010000058.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678075
            Sequence Read Archive: ERR226392
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12480)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12480)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980207.1
            Genome Coverage       :: 150x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:50:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 72 of 147
            Pseudo Genes (incomplete)         :: 72 of 147
            Pseudo Genes (internal stop)      :: 42 of 147
            Pseudo Genes (multiple problems)  :: 32 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12480
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678075-rid20185393.denovo.058"
                     /strain="KS 009"
                     /db_xref="taxon:1313"
     gene            298..558
                     /locus_tag="VQ543_001817"
     CDS             298..558
                     /locus_tag="VQ543_001817"
                     /inference="COORDINATES: protein motif:HMM:NF012235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HET2612492.1"
                     /translation="MSGGETKRVALAKIILKNPPLIFADELTASLDSTTSQGIMKLLL
                     GMKNKNRLIIIATHNPDIWNQADEVINLNQLLQSIYIFYILK"
     gene            complement(662..1132)
                     /locus_tag="VQ543_001818"
     CDS             complement(662..1132)
                     /locus_tag="VQ543_001818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001043003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HET2612493.1"
                     /translation="MNKSEHRHQLIRALITKNKIHTQAELQTLLAENDIQVTQATLSR
                     DIKNMNLSKVREEDSAYYVLNNGSISKWEKRLELYMEDALVWMRPVQHQVLLKTLPGL
                     AQSFGSIIDTLSFPDAIATLCGNDVCLIICEDADTAQKCFEELKKFAPPFFFEE"
     gene            complement(1149..3422)
                     /locus_tag="VQ543_001819"
     CDS             complement(1149..3422)
                     /locus_tag="VQ543_001819"
                     /EC_number="3.4.14.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Xaa-Pro dipeptidyl-peptidase"
                     /protein_id="HET2612494.1"
                     /translation="MRFNQYSYINFPKENVLSELKKCGFDLQNTANHKDSLETFLRRF
                     FFTYQDTNYPLSILAADKKTDLLTFFQSEDELTADIFYTVAFQLLGFSYLVDFEDSDV
                     FRKETGFPIIYGDLIENLYQLLNTRTKKGNTLIDQLVSDGLIPEDNDYHYFNGKSLAT
                     FSNQDVIREVVYVESRVDTDQKGLSDLVKVSIIRPRFDGKIPAIMTASPYHQGTNDKA
                     SDKALYKMEGELEVKLPHKIELEKPQLNLVQPQGKAELIAEAEEKLTHINSSYTLNDY
                     FLPRGFANLYVSGVGTKDSTGFMTNGDYQQIEAYKNVIDWLNGRCRAFTDHTRQRQVK
                     ADWSNGKVATTGLSYLGTMSNGLATTGVDGLEVIIAEAGISSWYNYYRENGLVTSPGG
                     YPGEDFDSLAELTYSRNLLASDYIRGNEAHQADLEKVKAQLDRKTGDYNQFWHDRNYL
                     LNAHKVKAEVVFTHGSQDWNVKPLHVYQMFHALPTHIHKHLFFHNGAHVYMNNWQSID
                     FRESINALLTKKLLGQETDFQLPTVIWQDNTAPQTWLSLDNFGGQENCETFSLGQEEQ
                     AIQNQYPDKDFERYGKTYQTFNTELYQGKANQITINLPVTKDLHLNGRAQLNLRIKSS
                     TNKGLLSAQLLEFGQKKYLQPYPAILSARTIDNGRYHMLENLCELPFRPEAQRVVTKG
                     YLNLQNRNDLLLVEDITADEWMDVQFELQPTIYKLKEGDTLRLVLYTTDFEITIRDNT
                     DYHLTVDLAQSMLTLPC"
     gene            3769..6870
                     /locus_tag="VQ543_001820"
     CDS             3769..6870
                     /locus_tag="VQ543_001820"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000561528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit alpha"
                     /protein_id="HET2612495.1"
                     /translation="MIAQLDTKTVYSFMESVISIEKYVRAAKEYGYTHLAMMDIDNLY
                     GAFDFLEITKKYGIHPLLGLEMTVFVDDQGVNLRFLALSSVGYQQLMKLSTAKMQGEK
                     TWSVLSQYLEDIAVIVPYFDRVESLELGCDYYIGVYPETLASEFHHPILPLYRVNAFE
                     SRDREVLQVLTAIKENLPLREVPLRSRQDVFISASSLEKLFQERFPQALDNLEKLISG
                     ISYDLDTSLKLPRFNPARPAVEELRERAELGLVQKGLTSKEYQDRLDQELSVIHDMGF
                     DDYFLVVWDLLRFGRSNGYYMGMGRGSAVGSLVSYALDITGIDPVEKNLIFERFLNRE
                     RYTMPDIDIDIPDIYRPDFIRYVGNKYGSKHAAQIVTFSTFGAKQALRDVLKRFGVPE
                     YELSAITKKISFRDNLKSAYEGNLQFRQQINSKLEYQKAFEIACKIEGYPRQTSVHAA
                     GVVISDQDLTNYIPLKYGDEIPLTQYDAHGVEASGLLKMDFLGLRNLTFVQKMQELLA
                     ETEGIHLKIEEIDLEDKETLALFASGNTKGIFQFEQPGAIRLLKRVQPVCFEDVVATT
                     SLNRPGASDYINNFVARKHGQEEVTVLDPVLEDILAPTYGIMLYQEQVMQVAQRLAGF
                     SLGKADILRRAMGKKDASAMHEMRASFIQGSLEAGHTVEKAEQVFDVMEKFAGYGFNR
                     SHAYAYSALAFQLAYFKTHYPAIFYQVMLNSSNSDYLIDALEAGFEVASLSINTIPYH
                     DKIANKAIYLGLKSIKGVSNDLALWIIENRPYSNIEDFIAKLPENYLKLPLLEPLVKV
                     GLFDSFEKNRQKVFNNLANLFEFVKELGSLFGDAIYSWQESEDWTEQEKFYMEQELLG
                     IGVSKHPLQAIASKAIYPITPIGNLSENSYAIILVEVQKIKVIRTKKGENMAFLQADD
                     SKKKLDVTLFSDLYRQVGQEVREGAFYYIKGKVQSRDGRLQMIAQEIREAVAERFWIQ
                     VKNHESDQEISRILEQFKGPIPVIIRYEEEQKTIVSPHHFVAKSDELEAKLNEIVMKT
                     IYR"
     gene            6952..7959
                     /gene="pfkA"
                     /locus_tag="VQ543_001821"
     CDS             6952..7959
                     /gene="pfkA"
                     /locus_tag="VQ543_001821"
                     /EC_number="2.7.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000820836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HET2612496.1"
                     /translation="MKRIAVLTSGGDAPGMNAAIRAVVRQAISEGMEVFGIYDGYAGM
                     VAGEIHPLDAASVGDIISRGGTFLHSARYPEFAQLEGQLKGIEQLKKHGIEGVVVIGG
                     DGSYHGAMRLTEHGFPAIGLPGTIDNDIVGTDFTIGFDTAVTTAMDAIDKIRDTSSSH
                     RRTFVIEVMGRNAGDIALWAGIATGADEIIIPEAGFKMEDIVASIKAGYECGKKHNII
                     VLAEGVMSAAEFGQKLKEAGDTSDLRVTELGHIQRGGSPTARDRVLASRMGAHAVKLL
                     KEGIGGVAVGIRNEKMVENPILGTAEEGALFSLTAEGKIVVNNPHKADIELSSLNKSL
                     S"
     gene            8016..9521
                     /gene="pyk"
                     /locus_tag="VQ543_001822"
     CDS             8016..9521
                     /gene="pyk"
                     /locus_tag="VQ543_001822"
                     /EC_number="2.7.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase"
                     /protein_id="HET2612497.1"
                     /translation="MNKRVKIVATLGPAVEIRGGKKFGEDGYWGEKLDVEASAKNIAK
                     LIEAGANTFRFNFSHGDHQEQGERMATVKLAEKIAGKKVGFLLDTKGPEIRTELFEGE
                     AKEYSYKTGEKIRVATKQGIKSTREVIALNVAGALDIYDDVEVGRQVLVDDGKLGLRV
                     VAKDDATREFEVEVENDGIIAKQKGVNIPNTKIPFPALAERDNDDIRFGLEQGINFIA
                     ISFVRTAKDVNEVRAICEETGNGHVQLFAKIENQQGIDNLDEIIEAADGIMIARGDMG
                     IEVPFEMVPVYQKMIIKKVNAAGKVVITATNMLETMTEKPRATRSEVSDVFNAVIDGT
                     DATMLSGESANGKYPLESVTTMATIDKNAQALLNEYGRLDSDSFERNSKTEVMASAVK
                     DATSSMDIKLVVTLTKTGHTARLISKYRPNADILALTFDELTERGLMLNWGVIPMLTD
                     APSSTDDMFEIAERKAVEAGLVESGDDIVIVAGVPVGEAVRTNTMRIRTVR"
     gene            complement(10253..10478)
                     /locus_tag="VQ543_001823"
                     /pseudo
     CDS             complement(10253..10478)
                     /locus_tag="VQ543_001823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001838792.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            11326..12198
                     /locus_tag="VQ543_001824"
     CDS             11326..12198
                     /locus_tag="VQ543_001824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000749590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4300 family protein"
                     /protein_id="HET2612498.1"
                     /translation="MKKSRKLATLGICSALFLGLAACQQQHATSEGTNQRQSSSAKVP
                     WKASYTNLNNQVSTEEVKSLLSAHLDPNSVDAFFNLVNDYNTIVGSTGLSGDFTSFTH
                     TEYDVEKISHLWNQKKGDFVGTNCRINSYCLLKNSVTIPKLEKNDQLLFLDNDAIDKG
                     KVFDSQDKEEFDILFSRVPTEATTDVKVHAEKMETFFSQFQFNEKARMLSVVLHDNLD
                     GEYLFVGHVGVLVPADDGFLFVEKLTFEEPYQAIKFASKEDCYKYLGTKYADYTGEGL
                     AKPFIMDNDKWVKL"
     gene            12211..12375
                     /locus_tag="VQ543_001825"
     CDS             12211..12375
                     /locus_tag="VQ543_001825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001836122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2612499.1"
                     /translation="MTVILGFLFLFLMTWWVISIVNSQKPRKNETFIGYIQRYDIDGN
                     GYQSLPCPQN"
     gene            complement(12344..12480)
                     /locus_tag="VQ543_001826"
                     /pseudo
     CDS             complement(12344..12480)
                     /locus_tag="VQ543_001826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
BASE COUNT         3808 a         2173 c         2665 g         3834 t
ORIGIN      
        1 ttgttttgtc gcttttcatt ataggtcata tgggactttt tttctacaat aaaataggct
       61 ccataatatc tatagtggat ttacccacta caaatattat agaacccttt tttattgaca
      121 gtatcaggat atctttttca aatttttggt ttgttagata atgaaaatgt ttctatcaat
      181 ctagatttag gattaataaa tcgtaaatgt aattataaag aaaaagataa gttaaaaaaa
      241 gatgtattag caagagttgg tctaactcat attcatctat aacaaaagat atatgaattg
      301 tctggcggtg aaacaaaacg tgttgcttta gcgaaaatca ttcttaaaaa tccaccatta
      361 atattcgcgg atgagttgac tgcatcactc gattcgacga cttcacaagg aattatgaaa
      421 ttgttattag gtatgaaaaa taaaaatcgt ctaatcatca ttgcaactca taatcccgat
      481 atttggaatc aagcagatga agttataaat ttaaatcaat tattacagtc aatatatatc
      541 ttctatattt taaagtaatt ttatctgaat ccgttaagag actattgtcc caggctcttt
      601 ctgatgttaa agactttcta ccaggttttt taaaagcata attgttagtt gtagtcattt
      661 attattcttc aaagaaaaat ggtggggcga attttttcag ttcttcaaag cacttttgag
      721 cagtatctgc atcttcacag atgataagac agacatcatt accacaaagg gtagcgatag
      781 cgtcagggaa gctcaaagta tcaatgatag aaccaaagga ttgagccagt ccaggaaggg
      841 tttttagtag gacttggtgt tgaactgggc gcatccagac aagggcgtct tccatgtaga
      901 gttcgagacg tttttcccat tttgagatgg aaccattgtt aagaacataa taagcgctat
      961 cttcttcgcg gacttttgat aggttcatat ttttgatgtc gcgtgagagg gttgcctgag
     1021 ttacttgaat gtcgttctca gcaagaaggg tttgcaactc agcctgtgta tgaatcttgt
     1081 tttttgtgat aagagcgcgt ataagttggt ggcggtgttc tgatttattc ataataatgt
     1141 aactcctttt agcaaggtaa ggtaagcatg gactgagcga ggtcgacagt caagtggtag
     1201 tctgtattgt cacggatggt gatttcaaag tcagtagtat agaggactaa acggagagtg
     1261 tctccttctt ttagcttgta aatagttggc tgcagttcaa attgaacgtc catccattca
     1321 tctgcagtaa tatcctctac taacagtaaa tcatttctat tttgtaaatt aaggtaacct
     1381 tttgtcacga ctctttgtgc ctctggtcta aatggcaatt cacagagatt ttccaacatg
     1441 tgatagcgac cgttgtcaat ggttctagca cttaaaatag ctggataagg ttgtaggtat
     1501 ttcttttgcc caaattctag cagttgggca gataagagcc ccttgtttgt actggatttg
     1561 atacgaagat tgagctgagc gcgaccgttt aggtggagat ctttagtcac aggaaggtta
     1621 atagtaatct gattagcttt cccttgatag agctctgtat tgaaggtttg gtatgtctta
     1681 ccatagcgct caaaatcctt atctgggtac tggttttgaa tagcttgctc ttcttgacca
     1741 agtgagaagg tttcacagtt ttcttgccca ccgaagttat caagtgataa ccaagtctgt
     1801 ggagctgtat tgtcctgcca gataacagta ggaagttgaa agtctgtttc ctgtcctagt
     1861 aatttcttgg tcaataaggc atttatggac tcacggaagt caattgattg ccaattgttc
     1921 atgtaaacat gggcaccatt atggaaaaag agatgcttgt gtatatgagt aggaagagca
     1981 tggaacatct ggtaaacatg aagtggtttg acattccaat cctgagaacc atgagtaaag
     2041 acaacctctg cctttacttt atgggcattg agcagataat tgcggtcatg ccaaaactga
     2101 ttgtagtccc cagtttttcg gtctagttga gctttcactt tttctaagtc agcttggtga
     2161 gcttcattgc cacggatata gtcgctagcc aagagattac gagaataggt taactcagca
     2221 agggagtcaa agtcctcacc tggataacca cctgggctag tcaccagacc gttttcacgg
     2281 tagtagttgt accatgatga aattcctgcc tcggcaatga taacttctaa accatcgact
     2341 cctgtagtcg caagaccatt ggacatggta cctagatagg aaagtcccgt tgtagcaact
     2401 tttccgtttg accaatcagc cttgacttga cgctggcgcg tgtgatcagt aaaggcacgg
     2461 caacggccgt taagccaatc gatgacattt ttataagcct cgatttgctg gtagtctcca
     2521 ttagtcatga aacctgtcga gtctttggta ccaacacctg agacatagag attggcaaag
     2581 cctctcggaa ggaagtagtc gtttagtgta tagctagagt tgatgtgagt tagcttttcc
     2641 tcagcctctg ctataagctc agctttacct tggggttgga cgagatttag ttgaggtttc
     2701 tctagctcaa tcttgtgagg aagtttaacc tcaagctcgc cctccatctt gtagagagcc
     2761 ttgtcactag ccttgtcatt ggttccctga tgataagggc tggctgtcat gatggcaggg
     2821 atttttccat caaaacgagg gcgaataatg ctaaccttta ctaggtctga tagccctttt
     2881 tggtcagtat cgacacgaga ctcaacgtaa acgacttcac gaatgacatc ctggttagaa
     2941 aaagtagcca aactcttgcc gttaaagtag tggtagtcat tatcctccgg aataagacca
     3001 tcactaacaa gttggtcgat aagagtattt ccttttttgg tgcgagtatt gagtaactga
     3061 tagagatttt caatcaagtc accatatata atgggaaatc cagtttcttt acgaaaaacg
     3121 tcactatctt cgaagtcaac caaataagaa aagcctaaaa gttgaaaagc aacagtataa
     3181 aaaatatctg ctgtcagttc atcttctgat tgaaaaaatg tcagcaggtc tgttttttta
     3241 tcagctgcta ggatagaaag tgggtagttg gtgtcttgat aagtgaaaaa gaaacgacgt
     3301 aaaaaggttt caagtgagtc tttgtgattg gctgtatttt gtaaatcaaa gccacatttt
     3361 tttagttcag ataagacatt ttcttttgga aaattgatat aactatattg attaaaacgc
     3421 atagaacctc catatagaat gacagttaag gttattatat caaaaaaaaa gcagaaaggg
     3481 aattgttaac ttcaaaagga aataatccaa taaaaatgaa taaagtacta aattcaatat
     3541 agagaacaga gtaacaataa gaataaatag atagggtata aaagttctag gagatttata
     3601 ttatatgctt tctgttttta tatacaatat agtataaata taaaaatgat gacaaaaata
     3661 caaatgaata gaaaataaat tagtaagctg atgaaatttt tctcaagaga agccatttat
     3721 aggtgaaaat ggtataatat agtgagaagg atagaggaga agtgtaaatt gatcgcacaa
     3781 ctagatacaa aaacagtcta tagttttatg gaaagcgtca tttcgatcga aaagtatgtg
     3841 agagcagcta aagaatacgg ctacactcat ttggctatga tggatattga caatctttat
     3901 ggcgctttcg actttctaga gattacaaaa aaatacggca ttcatccttt gctagggctt
     3961 gaaatgacag tgtttgtaga tgatcaggga gtgaatttgc gctttttagc tctatctagt
     4021 gtgggctatc agcagttgat gaagctttcg acagccaaga tgcaggggga gaaaacttgg
     4081 tcagtcctgt cccagtacct ggaggatatc gcggtcattg tgccttattt tgatagagtt
     4141 gagtcgttag aactaggctg tgattactat ataggggttt atccagaaac actagcaagc
     4201 gaatttcatc atcctatctt acctctttat cgggtcaacg cttttgaaag cagggataga
     4261 gaagttcttc aagttttaac agcgattaaa gaaaatctac cgctcagaga agttcccttg
     4321 cgttcgagac aagatgtctt tatatcagca agttctttag agaaactatt ccaagagcgt
     4381 tttccgcaag ctttggacaa tttagaaaag cttatttcag gcatttctta cgacttggat
     4441 actagtctga aactgcctcg ttttaatcca gctagaccag cagtagagga gttgagagag
     4501 cgtgctgaac tggggcttgt tcagaagggg ttgactagta aagaatatca agatagacta
     4561 gaccaagaat tgtctgttat tcatgatatg ggctttgatg attatttctt ggttgtttgg
     4621 gatttgttgc gttttggacg atcgaatggc tattatatgg gaatgggaag gggttctgca
     4681 gtaggcagtt tggtttctta tgccttagac atcacgggga ttgacccagt agagaaaaat
     4741 ctgatttttg aacgctttct taatcgtgaa cgctatacca tgcctgatat tgatattgat
     4801 atcccagata tttatcgtcc agattttatc agatatgttg gtaataaata tggtagtaaa
     4861 catgcggcac aaatcgttac tttttcaacc tttggagcca agcaagctct tcgagatgtc
     4921 ttgaaacgct ttggtgtgcc agagtatgaa ttatctgcaa ttactaagaa aatcagtttt
     4981 cgtgacaatc ttaagtcggc ctatgagggc aatctccagt ttcgtcagca aatcaatagt
     5041 aagttagaat accaaaaagc ttttgagatt gcttgcaaga tagagggcta tccaaggcaa
     5101 acctctgtcc atgcggctgg tgttgtaatt agtgaccaag atttaaccaa ctacattcct
     5161 ctaaagtatg gtgatgaaat tccactgact cagtatgatg ctcatggagt tgaggctagc
     5221 ggacttttga agatggactt tctgggacta cgaaatttga cctttgtcca gaagatgcaa
     5281 gagttgcttg ctgaaacaga aggtattcat ctgaaaattg aagaaatcga tttagaagac
     5341 aaagaaacat tagctttatt tgcctctggt aatacaaaag gtatctttca atttgagcaa
     5401 ccaggtgcca ttcgtctgct taagcgtgtg caaccagtct gttttgaaga tgtcgtcgcg
     5461 actacttctc taaatcgacc gggtgctagt gactatatca ataattttgt ggcaagaaag
     5521 catgggcagg aagaagtgac tgttctggat ccagtactgg aggatatttt ggctccaacc
     5581 tacggcataa tgctctatca ggagcaggtt atgcaggttg cccagcgact tgccggattt
     5641 agtcttggga aagccgatat tttgcgtcgg gctatgggga aaaaggatgc ctctgccatg
     5701 catgagatga gggcttcctt tattcaaggt tcattagaag ctggtcatac tgtggaaaaa
     5761 gcagagcagg tctttgatgt tatggagaag tttgcaggtt atggttttaa caggtcacac
     5821 gcctatgcct actcagcctt ggccttccag ttggcttatt tcaaaacgca ttatccagcc
     5881 attttttatc aggtcatgtt aaattcttcc aacagtgatt acttaataga tgcacttgaa
     5941 gcaggttttg aagtagcctc tctatccatc aacaccattc cctatcacga taaaattgcc
     6001 aacaaggcca tctatctagg tttgaaatcc attaaaggag tcagtaatga tttagctctc
     6061 tggattattg aaaatagacc ttattctaac attgaagatt ttatagctaa attacctgag
     6121 aattatctga aacttcctct gctagaacct ttggtaaaag ttggtctttt cgattcattt
     6181 gaaaaaaatc gtcaaaaagt atttaataac ttagctaatc tatttgaatt tgtgaaagag
     6241 ttgggaagtt tgtttggaga tgctatttat agttggcagg aatcggaaga ttggacggaa
     6301 caagaaaaat tttatatgga acaagagctt ttagggatag gtgtcagcaa acatccacta
     6361 caagctattg caagtaaggc tatttacccg attaccccaa tcggaaattt gtcagaaaat
     6421 agctatgcta ttatcttggt tgaagttcag aaaataaaag tgattcgtac caaaaagggt
     6481 gaaaatatgg ccttcttaca ggcagatgat agtaagaaaa aattggatgt tacactcttc
     6541 tcagatttat atcgacaggt tggtcaggaa gtaagagaag gagcattcta ctatatcaaa
     6601 gggaaagtcc aatcacgtga cggtcgtctg caaatgattg cacaagaaat aagagaagca
     6661 gttgctgaac gcttttggat acaggtgaaa aatcatgaat cggatcaaga aatttcacgt
     6721 attttagaac aatttaaagg cccaatccca gtcatcatcc ggtatgaaga ggaacagaaa
     6781 accatcgttt ctccccatca ttttgtagct aaatctgatg aattagaggc gaaattgaat
     6841 gaaatcgtta tgaaaacgat ttatcgctaa aaatacggaa aatagaagaa ttttaaaatc
     6901 aaatgtgata taatcaagaa gaatgttaaa agaaaaagga gcataaccaa tatgaaacgt
     6961 attgctgttt tgactagtgg tggagacgcc cctggtatga acgctgccat ccgtgcagtt
     7021 gttcgtcaag caatttcaga aggaatggaa gtgtttggta tctatgacgg atatgctggt
     7081 atggttgccg gtgaaattca tcccctagat gcagcttcag taggggacat catttctcgt
     7141 ggtggtactt tccttcactc agctcgttac ccagagttcg ctcaacttga agggcaactt
     7201 aaagggattg agcaattgaa aaaacacgga attgaaggtg tagttgttat cggtggtgac
     7261 ggatcttacc acggcgctat gcgtttgact gaacatggct tcccagctat tggtcttcca
     7321 ggtacaatcg ataacgatat cgttggtact gactttacaa tcggttttga cacagcggtt
     7381 actactgcca tggacgctat cgataagatt cgtgatacat catcaagtca ccgtcgtact
     7441 tttgtaatcg aagttatggg acgtaacgct ggtgatatcg ctctttgggc tggtattgca
     7501 actggtgctg atgaaatcat catccctgaa gcaggcttca agatggaaga tatcgtagca
     7561 agcatcaaag ctggttatga atgtggtaaa aaacacaata tcatcgtctt agctgaaggt
     7621 gtgatgtcag cggctgaatt tggtcaaaaa cttaaagaag ctggagatac aagcgacctt
     7681 cgtgtaacag aacttggaca tattcaacgt ggtggttctc caactgcgcg tgaccgtgtt
     7741 ttggcgtcac gtatgggtgc acatgctgtt aaacttctta aagaaggtat cggtggtgtt
     7801 gcggttggta ttcgtaacga aaaaatggtt gaaaatccaa ttcttggtac tgcagaagaa
     7861 ggggcattgt ttagccttac tgcagaaggt aagattgtgg ttaacaaccc gcacaaagcc
     7921 gatattgagc tatctagctt gaataagagc ttgtcataat ttacaattta gttaataaga
     7981 ccaaaaaggt catatataaa ggagtcacaa aaatcatgaa caaacgtgta aagatcgttg
     8041 caactttggg tcctgcggta gaaatccgtg gtggtaaaaa attcggtgag gacggatact
     8101 ggggtgaaaa acttgatgtt gaagcttcag ctaaaaacat tgctaaattg attgaagctg
     8161 gtgctaacac attccgattc aacttctcac acggcgacca ccaagaacaa ggtgagcgta
     8221 tggcaactgt taaacttgcg gaaaaaattg caggtaaaaa agttggtttc cttcttgata
     8281 caaaaggacc tgaaatccgt acagaattgt tcgaaggtga agctaaagaa tattcataca
     8341 aaactggtga aaaaattcgt gttgcaacta aacaaggaat caaatcaact cgtgaagtga
     8401 ttgcgttgaa cgttgctggt gctcttgata tctatgatga tgttgaagtt ggtcgtcaag
     8461 ttttggttga cgatggtaaa cttggtcttc gtgtggttgc taaagatgat gcaactcgtg
     8521 aatttgaagt tgaagttgaa aacgatggta tcatcgctaa acaaaaaggt gtgaacatcc
     8581 ctaacactaa aattcctttc ccagctcttg ctgaacgcga taacgacgat atccgtttcg
     8641 gtcttgaaca aggtatcaac ttcatcgcaa tttcattcgt acgtactgca aaagatgtga
     8701 acgaagttcg tgcaatctgt gaagaaactg gaaacggaca tgttcaatta ttcgctaaaa
     8761 tcgaaaacca acaaggtatc gataacttag acgaaatcat cgaagcagct gatggtatta
     8821 tgattgctcg tggtgatatg ggtatcgaag taccgttcga aatggttcca gtttatcaaa
     8881 aaatgattat caagaaagtc aatgctgcag gtaaagttgt tatcactgca acaaacatgc
     8941 ttgaaacaat gactgaaaaa ccacgtgcaa ctcgttcaga agtatcagac gtattcaacg
     9001 ctgttatcga cggaactgac gctacaatgc tgtcaggcga gtctgcaaac ggtaaatacc
     9061 cactcgagtc agtaactaca atggctacaa tcgacaagaa tgctcaagct cttcttaatg
     9121 aatacggacg tcttgattca gattcatttg agcgtaactc taagacagaa gtaatggctt
     9181 ctgctgttaa agatgctact agctcaatgg atatcaaatt ggtcgtaact cttactaaga
     9241 caggtcatac tgcacgtttg atttctaaat accgtccaaa tgctgacatc ttagcattga
     9301 catttgacga attgacagaa cgtggcttga tgttgaactg gggtgttatc ccaatgttga
     9361 cagatgctcc atcttcaact gacgatatgt tcgaaatcgc tgaacgtaaa gcggtagaag
     9421 caggtctcgt tgagtcaggc gatgatatcg ttatcgttgc tggtgtgcca gtaggagaag
     9481 ctgttcgcac aaacacaatg cgtatccgca cagtacgtta agaaaaatat aaaaacctat
     9541 catatccagc tttagagctt gtgtgatagg ctttttgtat agagggtaag aaataggcaa
     9601 aactttcata atggattgat actcttcgaa aatcaaattc aaaccacgtc agcgtcgcct
     9661 taccgtatat atgttactga cttcgtcagt tctatctaca acctcaaagc agtgctttga
     9721 gcaacctgcg gctagcttcc tagtttgctc tttgattttc attgagtatg aaataagata
     9781 tgcacaaatt gattaggaaa ttcaaatgaa tttctacaaa tgttttagca atcgtaatgt
     9841 acttgtctag attcgatctg atatattttc gatttaatga tatggtattt aaaacctcca
     9901 aagtagcttg ctccattctt ttacttacgt gagtgtagat gttatttact gttttagcgt
     9961 ttttgtgttc cactctaacc attatagcat tcttctcagc tagtgtacta aggagtgtgt
    10021 gcctgaaaat atgggaacta aggggctggt ttatcggttt ctctagttta gtatttgcct
    10081 tttgcaaagt gatgttaaat gcctttctct aaatttacat atcactattg tttaacaaaa
    10141 tctaatctac tttaggtcac ttattctttt tttgaaatgt agaatgaact ttttcaaagt
    10201 ttttcgaatc ttttaaaatc tgtttgtttt atatcgccat tctccccctt ttttaattct
    10261 ccctatatag cctgacaact ttcccgatgg tacgaatatg gttgctttcg tctaggtgga
    10321 tgtcggggta tttgggattg agttttttta aggtagcctt ggcggagttt cttgacatag
    10381 ttagcgccgt ctacttggaa gatgccgatg gtattatagt caatctgtgg ggtattcttg
    10441 ataaataggt agtcgctgtt tcttatcttt ggctccatgg acttgctgac gacataagcg
    10501 attgggtcgt agtcgtctgg gataatggaa actccataac taaatcgtcg tcctgcatcg
    10561 agcggctacc tgcagagata aactacctaa cacgagagta agtagtctgt ctgtagtcgt
    10621 ccagtctgat gatttttacg atatttcgtt tttctgctca tacagttgcc tctcggcata
    10681 ggtcagaact ttaccttgtc tgggtggtgc ccgttggtcg tagatagatt ggatatcgct
    10741 aggagaatcc ttttgaactg gaggaaagag ggtatcaatc aagctactga atactttagc
    10801 taagtcaaat atagtatttt tcttagtaga cctaaccctt ttttcataat ttccaatggt
    10861 gtttttactt ataccaatct tagtacccaa ttcttattga gtccaaccat tactagtcta
    10921 tattgtttta tagttgattg agtttggaat agtacgctgt agctgctaaa acatttctag
    10981 gaattaattt gactttccta atagagttgt tcatatctta tttcaatcta ctatgttttt
    11041 cacctctaac aatcgcaatc tcttctttat ccatgaatga aatcgctttc tatttttgta
    11101 agtaaagcat cacacgaaat ccacgaaaat gaaaaccttt gttgtgtttt cgtaaaaaat
    11161 ttgttgacag agcacgaaac gcctactata attaaatcaa gcttaaggaa ataacaaaaa
    11221 aacaaatcgg agggaaagac gatgaacaca ttaaatgaga aagtaatcaa tatctgtaaa
    11281 gcagtagtta aagaaacttt aatccaagac atttaggaga aagaaatgaa gaaatcaaga
    11341 aaattagcca cattaggaat ctgttcagcc ttgtttttag gcttggctgc ttgtcaacaa
    11401 caacatgcta cttctgaggg gacgaatcaa aggcaaagca gttcagcgaa agttccatgg
    11461 aaagcttcat acaccaacct aaacaaccag gtaagtacag aagaggtcaa atctctctta
    11521 tcagctcact tggatccaaa tagtgttgat gcatttttta atctcgttaa tgactataat
    11581 accattgtcg gctcaactgg cttatcagga gatttcactt cctttactca caccgaatac
    11641 gatgttgaga aaatcagtca tctctggaat caaaagaagg gcgatttcgt tgggaccaac
    11701 tgccgtatca atagttattg tcttttgaaa aattcagtca ccattccaaa gcttgaaaag
    11761 aatgaccaat tgcttttcct agataacgat gcgattgata aaggaaaggt ctttgattca
    11821 caagataagg aagagtttga tattctattt tcgagagttc caactgaggc aactacagat
    11881 gtcaaggttc acgctgaaaa gatggaaaca ttcttctcac aatttcaatt caatgaaaaa
    11941 gctcgaatgc tgtctgtagt cttgcacgac aatctggatg gcgagtatct gtttgtaggc
    12001 catgttgggg tcttagtacc tgctgatgac ggtttcttat ttgtagagaa attgactttc
    12061 gaagagccct accaagcgat taaatttgct agtaaggaag attgctacaa gtatttgggc
    12121 accaagtatg cggattatac aggcgaggga ctggctaagc cttttatcat ggataatgat
    12181 aagtgggtta aactttaata gtgttatgat atgacagtaa tcttaggatt tttatttcta
    12241 tttttgatga cttggtgggt tatttcaatc gttaatagcc agaaaccacg caaaaatgaa
    12301 acatttattg gctatatcca aagatacgat attgatggga atggctatca atcattaccg
    12361 tgtcctcaga actgagagga gttcttgaaa ccgtaaaacc gctttgaaca agagttactt
    12421 caacccattg gctccgacgg agtaagttgc tttcgtgaat accaaaatca gccgcaattt
//
LOCUS       DAVBEO010000059        12042 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 009
            SAMEA1678075-rid20185393.denovo.059, whole genome shotgun sequence.
ACCESSION   DAVBEO010000059 DAVBEO010000000
VERSION     DAVBEO010000059.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678075
            Sequence Read Archive: ERR226392
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12042)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12042)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980207.1
            Genome Coverage       :: 150x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:50:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 72 of 147
            Pseudo Genes (incomplete)         :: 72 of 147
            Pseudo Genes (internal stop)      :: 42 of 147
            Pseudo Genes (multiple problems)  :: 32 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12042
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678075-rid20185393.denovo.059"
                     /strain="KS 009"
                     /db_xref="taxon:1313"
     gene            275..2566
                     /gene="pcrA"
                     /locus_tag="VQ543_001827"
     CDS             275..2566
                     /gene="pcrA"
                     /locus_tag="VQ543_001827"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000992850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase PcrA"
                     /protein_id="HET2612500.1"
                     /translation="MNALLNGMNDRQAEAVQTTEGPLLIMAGAGSGKTRVLTHRIAYL
                     IDEKLVNPWNILAITFTNKAAREMKERAYSLNPATQDCLIATFHSMCVRILRRDADHI
                     GYNRNFTIVDPGEQRTLMKRILKQLNLDPKKWNERTILGTISNAKNDLIDDVAYAAQA
                     GDMYTQIVAQCYTTYQKELRQSESVDFDDLIMLTLRLFDQNPDVLTYYQQKFQYIHVD
                     EYQDTNHAQYQLVKLLASRFKNICVVGDADQSIYGWRGADMQNILDFEKDYPKAKVVL
                     LEENYRSTKTILQAANEVIKNNKNRRPKNLWTQNADGEQIVYYRADDELDEAVFVART
                     IDELSRSQNFLHKDFAVLYRTNAQSRTIEEALLKSNIPYTMVGGTKFYSRKEIRDIIA
                     YLNLIANLSDNISFERIINEPKRGIGLGTVEKIRDFANLQNMSMLDASANIMLSGIKG
                     KAAQSIWDFANMMLDLREQLDHLSITELVESVLEKTGYVDILNAQATLESKARVENIE
                     EFLSVTKNFDDTTDVTEEETGLDKLSRFLNDLALIADTDSGSQETSEVTLMTLHAAKG
                     LEFPVVFLIGMEENVFPLSRATEDPDELEEERRLAYVGITRAEKILYLTNANSRLLFG
                     RTNYNRPTRFINEISSDLLEYQGLARPANTSFKASYSSGSISFGQGMSLAQALQDRKR
                     GAAPKSIQSSGLPFGQFTAGAKSASSEANWSIGDIALHKKWGEGTVLEVSGSGARQEL
                     KINFPEVGLKKLLASVAPIEKKI"
     gene            2609..3289
                     /gene="radC"
                     /locus_tag="VQ543_001828"
     CDS             2609..3289
                     /gene="radC"
                     /locus_tag="VQ543_001828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000286923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadC"
                     /protein_id="HET2612501.1"
                     /translation="MYSISFQEDSLLPRERLAKEGVEALSNQELLAILLRTGTRQASV
                     FEIAQKVLNNLSSLTDLKKMTLQELQSLSGIGRVKAIELQAMIELGHRIHKHETLEME
                     SILSSQKLAKKMQQELGDKKQEHLVALYLNTQNQIIHQQTIFIGSVTRSIAEPREILH
                     YAIKHMATSLILVHNHPSGAVAPSQNDDHVTKLVKEACELMGIVLLDHLIVSHSNYFS
                     YREKTDLI"
     gene            complement(3286..3975)
                     /locus_tag="VQ543_001829"
     CDS             complement(3286..3975)
                     /locus_tag="VQ543_001829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HET2612502.1"
                     /translation="MKKPVIGITGNEKAHPDDDIMMSYAAKGFVEGVKDAGGIPIILP
                     IGDQEMACHYISLIDKLILTGGQNVDPKFYGEPKTIDSDDYNLQRDIFELALIKEAIK
                     QKKPIFSVCRGTQLFNVAMGGTLYQDIEDHWQDSSVEYTTQRLVTEPDTVLQEIYGEI
                     SHINSFHHQSIKDLAPNLKVVAHDPKDGIIEAVMSTDDVAFLGVQWHPELLFENRPKD
                     KKLFDYVVNEL"
     gene            complement(3993..4634)
                     /locus_tag="VQ543_001830"
     CDS             complement(3993..4634)
                     /locus_tag="VQ543_001830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000653420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HET2612503.1"
                     /translation="MKDKQFSIPKATAKRLSLYYRIFKRFHAEKIERANSKQIAEAIG
                     IDSATVRRDFSYFGELGRRGFGYDVKKLMTFFADLLNDNSITNVMLVGIGNMGHALLH
                     YRFHERNKMKIIMAFDLDDHPEVGTQTPDGIPIYGISQIKDKIKDADVKTAILTVPSV
                     KSQEVANLLVDAGVKGILSFSPVHLHLPKDVVVQYVDLTSELQTLLYFMRKED"
     gene            complement(4717..4932)
                     /locus_tag="VQ543_001831"
     CDS             complement(4717..4932)
                     /locus_tag="VQ543_001831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000462494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4649 family protein"
                     /protein_id="HET2612504.1"
                     /translation="MFELTYKDCYHVERTLKYEDHEALMLTLSGCVTLPDTLYVTSLT
                     FRGQKVYQGLVGDLYRFLSHADFLHQN"
     gene            complement(4940..5287)
                     /locus_tag="VQ543_001832"
     CDS             complement(4940..5287)
                     /locus_tag="VQ543_001832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1831 domain-containing protein"
                     /protein_id="HET2612505.1"
                     /translation="MAFEKIIQLKNCRYDYTLSPSVKKFTLKDNTFFETKVGNYELTR
                     LLEKVPNSGEGFQLKIIINKELTGAKINITDKFSLRLVDIFKSEDHHIHQEKFYFLMD
                     SLVERGVFTKSER"
     gene            complement(5292..6407)
                     /locus_tag="VQ543_001833"
     CDS             complement(5292..6407)
                     /locus_tag="VQ543_001833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HET2612506.1"
                     /translation="MIYLDNAATTPMSAVAISAMTKVMQETHGNPSSIHGHGRQAGKL
                     LREARQELAQLLRTKPQHIFFTSGGTEGNNTTIIGYCLRHQEQGKHIITTAIEHHAVL
                     ETIDYLVQHFGFEATIIQPENQEITAQQIQKALRDDTILVSTMFANNETGNLLPIAEI
                     GQILKQHPAAYHVDAVQAIGKIPIHSEELGIDFLTASAHKFHGPKGIGFLYASSMDFD
                     SYLHGGDQEQKKRAGTENLPAIVGMVAALKEDLEKQEEHFQHVQNLETAFLAELEGIQ
                     YYLNRGKHHLPYVLNIGFPGQKNDLLLLRLDLAGISISTGSACTAGVVQSSHVLEAMY
                     GANSERLKESLRISLSPQNTVEDLQTLAKTLKEIIGG"
     gene            complement(6417..7376)
                     /locus_tag="VQ543_001834"
     CDS             complement(6417..7376)
                     /locus_tag="VQ543_001834"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HET2612507.1"
                     /translation="MSDRKNMKLFALNSNQEIAQKIAQAVGVPLGKLSSRQFSDGEIQ
                     VNIEESVRGYDVYIIQSTSFPVNNHLMELLIMVDACVRASAHSINVVLPYFGYARQDR
                     IACPREPLTAKLVANMLVKAGVDRILTLDLHAVQVQGFFDIPVDNLFTVPLFAKHYCD
                     KGLLGSDVVVVSPKNSGVKRARSLAEYLDAPIAIIDYPQDDATRNEGYIIGDVEGKKA
                     ILIDDILNTGRTFSEASKIVEREGATEIYAVSSHGLFVEGAAELLDNTNIKEILVTDS
                     VATKEKTPKNVCYITASELIGDAIVRIHERKPVSPLFAYNKKK"
     gene            complement(7489..8058)
                     /locus_tag="VQ543_001835"
     CDS             complement(7489..8058)
                     /locus_tag="VQ543_001835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000681289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CYTH domain-containing protein"
                     /protein_id="HET2612508.1"
                     /translation="MKHLEIELKTLLKKDEYNRLKDQFTGVTPVLQTNYYIDTPDFEL
                     REKKVAMRIRTFEDWAELTLKVPQSVGNMEYNQKLQLKDAEDYLSKEELPQGLVLDEL
                     AKHGIQSKNWQVLGCLTTLRYEMKTAIGLMALDQSRYFDITDYELELEVENHEQGKQD
                     FRQFLEKNQISYQKAPSKLVRFVKSMKNS"
     gene            8186..8857
                     /locus_tag="VQ543_001836"
     CDS             8186..8857
                     /locus_tag="VQ543_001836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000171686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase family protein"
                     /protein_id="HET2612509.1"
                     /translation="MTLEWEEFLDPYIQAVGELKIKLRGIRKQYRKQNKHSPIEFVTG
                     RVKPIESIKEKMARRGITYATLEHDLQDIAGLRVMVQFVDDVKEVVDILHKRQDMRII
                     QERDYITHRKASGYRSYHVVVEYTVDTINGAKTILAEIQIRTLAMNFWATIEHSLNYK
                     YQGDFPDEIKKRLEITARIAHQLDEEMGEIRDDIQEAQALFDPLSRKLNDGVGNSDDT
                     DEEYR"
     gene            8841..9659
                     /locus_tag="VQ543_001837"
     CDS             8841..9659
                     /locus_tag="VQ543_001837"
                     /EC_number="2.7.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000799053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD kinase"
                     /protein_id="HET2612510.1"
                     /translation="MKNTGKRIDLIANRKPQSQRVLYELRDRLKRNQFILNDTNPDIV
                     ISIGGDGMLLSAFHKYENQLDKVRFIGLHTGHLGFYTDYRDFELDKLVTNLQLDTGAR
                     VSYPVLNVKVFLENGEVKIFRALNEASIRRSDRTMVADIVINGVPFERFRGDGLTVST
                     PTGSTAYNKSLGGAVLHPTIEALQLTEIASLNNRVYRTLGSSIIVPKKDKIELIPTRN
                     DYHTISVDNSVYSFRNIERIEYQIDHHKIHFVATPSHTSFWNRVKDAFIGEVDE"
     gene            9656..10552
                     /locus_tag="VQ543_001838"
     CDS             9656..10552
                     /locus_tag="VQ543_001838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001209987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HET2612511.1"
                     /translation="MRFEFIADEHVKVKTFLKKHEVSKGLLAKIKFRGGAILVNNQPQ
                     NATYLLDVGDYVTIDIPAEEGFETLEAIEHPLDILYEDDHFLVLNKPYGVASIPSVNH
                     SNTIANFIKGYYVKQNYENQQVHIVTRLDRDTSGLMLFAKHGYAHARLDKQLQKKSIE
                     KRYFALVKGDGHLEPEGEIIAPIARDEDSIITRRVAKGGKYAHTSYKIVASYGNIHLV
                     YIHLHTGRTHQIRVHFSHIGFPLLGDDLYGGSLEDGIQRQALHCHYLSFYHPFLEQDL
                     QLESPLPDDFSNLITQLSTNTL"
     gene            10596..11570
                     /gene="pta"
                     /locus_tag="VQ543_001839"
     CDS             10596..11570
                     /gene="pta"
                     /locus_tag="VQ543_001839"
                     /EC_number="2.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acetyltransferase"
                     /protein_id="HET2612512.1"
                     /translation="MEVFESLKANLVGKNARIVLPEGEEPRILQATKRLVKETEVIPV
                     LLGNPEKIKIYLEIEGIMDGYEVIDPQHYPQFEEMVSALVERRKGKMTEEDVRKVLVE
                     DVNYFGVMLVYLGLVDGMVSGAIHSTASTVRPALQIIKTRPNVTRTSGAFLMVRGTER
                     YLFGDCAININPDAEALAEIAINSAITAKMFGIEPKIAMLSYSTKGSGFGESVDKVVE
                     ATKIAHDLRPDLEIDGELQFDAAFVPETAALKAPGSTVAGQANVFIFPGIEAGNIGYK
                     MAERLGGFAAVGPVLQGLNKPVNDLSRGCNADDVYKLTLITAAQAVHQ"
     gene            complement(11886..>12042)
                     /locus_tag="VQ543_001840"
     CDS             complement(11886..>12042)
                     /locus_tag="VQ543_001840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET2612513.1"
                     /translation="YSNAKLEATNNLIKLIKRNAFGFRNFENFKKRIFTALNIKKERT
                     KFVLSRA"
BASE COUNT         3502 a         2299 c         2593 g         3648 t
ORIGIN      
        1 caacctatcg aaatcatcgt aaacgcttcg gattacgaat gaatttgatt gctggcatta
       61 tcaatcatga actaggattc tagttttgca ggaagtctat tgaggtattg agctagttta
      121 tgaaaaaatt gggtgaaaaa gtcgagtgtt ttagaaaccc acagtgtagt attctagttt
      181 caatccacta tattttgcta ctccccgtaa agtttctatt ttccctgatt tctgatataa
      241 tagaaatatt gacttcaaga gtaaggaaga gaagatgaac gcattattaa atggaatgaa
      301 tgaccgtcag gctgaggcgg tgcaaacgac agaaggtccc ttgctaatca tggcaggagc
      361 tggttctgga aagactcgtg ttttaaccca ccgtatcgct tatttgattg atgaaaagct
      421 ggtcaatcct tggaatatct tggccattac ctttaccaac aaggctgcgc gtgagatgaa
      481 agagcgtgct tatagcctca atccagctac tcaggactgt ctgattgcga ccttccactc
      541 catgtgtgtg cgtattttgc gtcgcgatgc ggaccatatt ggctacaatc gtaattttac
      601 aattgtggat cctggtgaac agcgaacgct catgaaacgt attctcaaac agttgaactt
      661 ggatcctaaa aaatggaatg aacgaactat tttggggacc atttccaatg ctaagaatga
      721 tttgattgat gatgttgctt atgctgctca agctggcgat atgtatacgc aaattgtggc
      781 ccagtgttat acaacctatc aaaaagaact tcgtcagtct gaatccgttg actttgatga
      841 tttgattatg ctgaccttgc gtctctttga tcaaaatcct gatgttttga cctactacca
      901 gcaaaaattc caatacatcc acgttgatga gtaccaagat accaaccacg ctcagtacca
      961 attggtcaaa ctcttggctt cccgttttaa aaatatctgt gtggttgggg atgcggacca
     1021 gtctatctac ggttggcgtg gtgctgatat gcagaatatc ttggactttg aaaaggatta
     1081 ccccaaagct aaggttgttt tgttggagga aaattaccgc tcaaccaaaa ccattctcca
     1141 agcggccaac gaggttatta aaaataataa aaatcgccgt cctaaaaatc tctggactca
     1201 aaacgctgat ggggagcaaa tcgtttacta tcgtgctgat gatgagctgg atgaggctgt
     1261 atttgtagcc agaaccatcg atgaacttag tcgcagtcaa aacttccttc ataaggattt
     1321 tgcagttctc tatcggacta atgcccagtc ccgtacaatt gaggaagccc tgctcaagtc
     1381 taacattcct tataccatgg ttggcggaac caaattctac agccgtaagg aaattcgcga
     1441 tattattgct tatctcaacc ttattgctaa tttgagtgac aacattagtt ttgagcgtat
     1501 tatcaacgag cctaaacgtg gaattggtct aggtacagtt gagaaaatcc gtgattttgc
     1561 aaatttgcaa aatatgtcta tgctggatgc ttctgctaat attatgttgt ctggtatcaa
     1621 gggtaaggca gcccaatcta tctgggattt tgccaatatg atgcttgatt tgcgggagca
     1681 gctagaccac ttaagcatta cagagttggt tgagtccgtc ctagaaaaaa caggttatgt
     1741 cgatattctt aacgcccaag cgactctaga aagcaaggca agggttgaaa atatcgaaga
     1801 gtttctttct gttacgaaga actttgatga caccactgat gtgacagaag aggaaactgg
     1861 tctggacaaa ctgagtcgtt tcttaaatga cttggctttg attgccgaca cagattcagg
     1921 tagtcaggag acatcagaag tgaccttgat gaccctgcat gctgccaaag gtctcgaatt
     1981 tccagttgtc tttttgattg ggatggaaga aaatgtcttt ccacttagtc gtgcgactga
     2041 agatccagat gaattagaag aagagcgccg tctagcctat gtaggtatca cgcgtgcaga
     2101 gaaaattctc tatctgacca atgccaactc acgcttgctt tttggtcgta ccaattataa
     2161 ccgtccgact cgttttatta acgaaatcag ttcagacttg cttgagtatc aaggtctggc
     2221 tcgtcctgca aatacaagct ttaaggcatc atatagcagt ggtagtattt cctttggtca
     2281 aggtatgagt ttggctcagg ctcttcaaga ccgtaaacgc ggtgctgccc caaaatcgat
     2341 ccagtcaagc ggtcttccat ttggtcaatt tacagctggc gcaaaatcag catctagcga
     2401 ggcaaattgg tccattggtg acattgctct ccacaagaaa tggggagagg gaactgttct
     2461 ggaagtttca ggtagcggtg ctaggcagga attgaaaatc aatttcccag aagtaggttt
     2521 gaaaaaactt ttagccagtg tggctccaat tgagaaaaaa atctaatttt ccatccttct
     2581 cacgaataat aaagtgagga ggatttttat gtacagtatt tcattccaag aagattcact
     2641 attaccaaga gaaaggctgg ccaaggaagg agttgaagcg cttagtaacc aagagttgct
     2701 agctatttta ctcaggacag gaacacgtca agctagcgtt tttgaaattg cccaaaaagt
     2761 cttgaacaat ctttcaagcc taacggattt gaaaaaaatg accctgcagg aattgcagag
     2821 tttgtctggt attgggcgtg ttaaggccat agaattacaa gctatgattg aactggggca
     2881 tcgtattcac aaacacgaga ctcttgaaat ggaaagtatt ctcagcagtc aaaagttggc
     2941 caagaagatg cagcaggaat taggggataa aaaacaagag cacctggtgg cactctatct
     3001 caatactcaa aatcaaatca tccatcagca gaccattttt atcggttctg taactcgtag
     3061 tatcgctgaa ccgcgagaga ttcttcacta tgcaatcaag catatggcga cttctcttat
     3121 cttggtccac aatcatcctt caggagcggt agcgcctagc caaaatgatg atcatgtcac
     3181 taaacttgtt aaagaagcct gcgaattgat ggggattgtt ctcttggacc atttgattgt
     3241 ctctcattct aattacttta gttatcgtga aaagacagat ttaatctaaa gttcattaac
     3301 gacatagtca aagagttttt tatctttggg acgattttca aaaagaagtt ctggatgcca
     3361 ttggacaccg agaaaggcga catcatccgt actcatgaca gcctcaatga taccatcttt
     3421 aggatcatga gccacaactt ttaaatttgg tgctaagtcc ttgatgctct ggtggtggaa
     3481 ggagttgata tgagagattt ctccatagat ttcttggaga acggtatctg gttctgttac
     3541 caagcgttga gttgtgtact caacagaaga atcctgccaa tggtcttcga tatcttggta
     3601 caaagttcca cccatggcaa cgttaaagag ttgggtacca cggcagacag agaaaatggg
     3661 ctttttctgt ttaatagctt ccttgatgag ggccagttcg aagatatctc tttgaaggtt
     3721 atagtcatcg ctatcaatgg ttttgggttc gccataaaat tttggatcga cattttgccc
     3781 acctgtcaag atgagcttgt caatcaaact gatatagtgg caggccattt cttgatcacc
     3841 aatcggtagg atgatgggaa tccctccagc atctttaacg ccttcaacaa agccttttgc
     3901 tgcgtagctc atcatgatgt catcatctgg atgagctttt tcgtttcctg taatcccaat
     3961 aactggtttt ttcataaaat gattttcgct ttctaatcct cttttcgcat gaagtagagg
     4021 agggtttgga gttcacttgt caaatcgaca tactgaacga ccacgtcttt tggtaaatgc
     4081 agatggactg gtgaaaaact gagaattcct ttcacaccag catcaaccaa gagattagca
     4141 acctcttgtg acttgacgct gggaacagtt aggatagcag tcttcacatc agcatccttg
     4201 attttatcct tgatctgaga aatcccgtaa atgggaatcc cgtcaggagt ttgggtaccg
     4261 acttcaggat ggtcgtctag gtcaaaggcc atgataatct tcatcttgtt acgttcgtgg
     4321 aagcggtagt ggagaagggc atggcccata tttccaatac caaccagcat gacattggta
     4381 atagagttgt cattgagcaa atcggcaaaa aatgtcatta gttttttgac atcatagcca
     4441 aaaccacgac gaccaagttc accaaaatag gaaaaatcac gacgtacggt cgctgaatca
     4501 ataccgatag cctctgcaat ttgcttagag ttggcacgtt caatcttttc tgcatgaaat
     4561 ctcttaaaaa ttcgatagta gagagagagt ctttttgctg tagcttttgg aatagaaaac
     4621 tgtttatctt tcacaaaatc acaacctttc tattcttcta ttttatagaa acattgtgaa
     4681 aaaatcaaca aaaataagaa aaaactaaga aaaatcttag ttttgatgta aaaaatctgc
     4741 atgagataga aaacggtaga ggtctccgac cagaccctga taaacttttt ggcccctaaa
     4801 agtcagagaa gtcacataaa gtgtatctgg taaggttaca catcctgaca aagtcaacat
     4861 gagagcctca tgatcctcat acttgagagt acgctctaca tgatagcagt ccttataggt
     4921 cagttcaaac attttggctc tatctttccg attttgtaaa gacaccacgt tctaccaagc
     4981 tatccatgag gaagtagaat ttttcctgat gaatatggtg gtcttctgat ttgaaaatat
     5041 caactagacg aaggctaaac ttgtcagtga tattgatttt agcccctgta agttccttgt
     5101 taatgatgat tttgagttgg aagccttcac cgctgtttgg cactttttcc aaaaggcgag
     5161 tcagttcata gttaccaacc ttagtttcaa aaaaggtgtt atctttgagg gtgaattttt
     5221 taacagaagg gctaagagtg taatcgtaac gacaattttt taactgaatg attttttcaa
     5281 atgccatatg gctaacctcc gataatttct tttaaggttt ttgcgagggt ttgtaggtct
     5341 tcaacggtat tttgtggcga caaactgatg cgaagggatt ccttcaagcg ttctgaattt
     5401 gcgccataca tggcttcaag aacatggctg gattggacaa cgcctgcagt acaggctgag
     5461 ccagtagaga ttgaaattcc agctaaatct agccgaagga gtaagaggtc atttttctga
     5521 ccaggaaatc caatattgag aacataaggg agatgatgtt ttcctctatt caagtaatac
     5581 tgaatgccct ccagctctgc cagaaaggcg gtttctagat tttgtacatg ttgaaaatgt
     5641 tcttcttgtt tttctaggtc ttcttttagg gctgcaacca tgcctacgat agcaggcaga
     5701 ttttcagttc ctgcacgttt tttctgttcc tggtctccgc catgtagata ggaatcaaag
     5761 tccatgctag atgcgtagag aaaaccgatt cccttaggac catggaattt gtgggcagaa
     5821 gcagtgagaa aatcaatgcc caattcttct gaatgaattg ggattttacc aatagcctga
     5881 actgcatcaa catgataggc agcagggtgt tgcttgagta tttggccaat ttcagcgatg
     5941 ggcagtaggt ttcctgtctc attattggca aacatggtag aaaccaaaat cgtatcgtca
     6001 cgtaaagcct tttgaatttg ctgggctgtg atttcttgat tttctggctg gataatggtt
     6061 gcttcaaacc caaagtgttg aaccaagtaa tcaattgttt caaggacagc atggtgctcg
     6121 atggcagttg tgatgatatg ttttccttgt tcttggtgac gaagacagta gccaatgatg
     6181 gtagtattat tgccttcagt cccaccagaa gtgaaaaaga tatgttgagg ttttgtcctt
     6241 agtaactggg ctagttcctg acgggcttct cgcaagagtt tgccagcttg acgaccatga
     6301 ccatgaatac tagaaggatt tccgtgggtt tcttgcataa ccttggtcat agctgaaata
     6361 gcaactgctg acataggagt cgttgcagca ttgtccaaat aaatcaaaga atcaccttat
     6421 ttctttttat tgtaggcaaa gagtgggctg actggttttc tttcgtgaat acggacgata
     6481 gcatcaccaa ttaactcact agcagtgatg tagcatacat ttttaggagt tttttctttt
     6541 gttgctactg aatcagtcac aagaatttct ttaatattag tattgtcaag aagctcagca
     6601 gctccctcga cgaagagacc gtggctagaa acagcataaa tttctgtagc tccttcacgt
     6661 tcaacgattt tagaagcttc agagaaggta cgtcctgtat ttaaaatatc atcaatcaag
     6721 atagctttct taccttcaac atcaccaata atataacctt cgttacgagt tgcatcgtct
     6781 tgagggtagt cgataatggc gataggagca tcaagatatt cagccaggct acgcgcacgt
     6841 ttgacacctg aatttttagg gctaacgaca acaacatctg aaccaagcaa tcctttatcg
     6901 cagtaatgtt ttgcgaatag gggaacagtg aaaagattat ccactggaat atcaaagaaa
     6961 ccttgaacct gaacggcatg caaatcaaga gtcaggatac gatcaactcc agccttaacc
     7021 agcatattgg caactagttt tgctgtaagt ggctcacgag gacaagcaat gcggtcttga
     7081 cgtgcatagc caaaatatgg aaggacaacg ttgatactgt gggcacttgc acgcacacaa
     7141 gcatcgacca tgattaacaa ttccattagg tggttgttga cagggaaact tgttgattgg
     7201 atgatgtaaa catcataacc acggacactt tcttcgatat ttacttggat ttctccgtct
     7261 gaaaattgac gtgatgatag ttttccaagt gggacaccaa cagcttgggc aattttttgt
     7321 gcaatctctt ggttagagtt gagtgcgaaa agtttcatgt tttttctatc tgacattata
     7381 gaccgtcctc tgtaaacttt ataaatccta gttatattta ccttacatat atgaactggg
     7441 atttgtgtat ttttatcttt tctattttac caaaaaatgg agattatttc agctattttt
     7501 catacttttg acaaatcgaa ccaattttga aggagctttt tggtaggaaa tctgattttt
     7561 ctctaaaaat tgtcggaaat cctgtttgcc ttgctcatga ttttccactt caagctccaa
     7621 ttcgtaatct gttatatcaa agtatcggct ctgatccagt gccatgagac caatagctgt
     7681 tttcatttca tagcgaagcg ttgttagaca accaagaacc tgccagttct tactttggat
     7741 accatgtttc gccaattcat ccagtactag tccttgagga agttcttcct tactcagata
     7801 gtcctcagca tcttttagtt gcaatttttg gttgtattcc atgtttccaa cactctgcgg
     7861 gactttgagt gtcaactcag cccagtcttc aaaggttcga atgcgcatag cgactttctt
     7921 ttctcgcagt tcaaaatcag gcgtgtcgat gtagtaattt gtttgaagaa caggagtgac
     7981 acctgtgaac tggtctttta gacgattgta ttcatctttt ttcaatagtg ttttcaattc
     8041 aatttctaaa tgtttcattt ttcttacctt tttttatcgt tgaaagcgga tttatggtat
     8101 aataagcatt gtatttattg tatatgaatc tggagaaaaa atcaaagata tttttgacgg
     8161 ataatatgag aacaagggag aatatatgac cttagaatgg gaagaatttc tagatcctta
     8221 cattcaagct gttggtgagt taaagattaa acttcgtggt attcgtaagc aatatcgtaa
     8281 gcaaaataag cattctccaa ttgagtttgt gaccggtcga gtcaagccaa ttgagagcat
     8341 caaagaaaaa atggctcgtc gtggcattac ttatgcgacc ttggaacacg atttgcagga
     8401 tattgctggc ttacgtgtga tggttcagtt tgtagatgac gtcaaggaag tagtggatat
     8461 tttgcacaag cgtcaggata tgcgaatcat acaggagcga gattacatta ctcatagaaa
     8521 agcatcaggc tatcgttcct atcatgtggt agtagaatat acggttgata ccatcaatgg
     8581 agctaagact attttggcag aaattcaaat tcgtactttg gccatgaatt tctgggcaac
     8641 gatagaacat tctctcaact acaagtacca aggggatttc ccagatgaga ttaagaagcg
     8701 actggaaatt acagctagaa tcgcccatca gttggatgaa gaaatgggtg aaattcgtga
     8761 tgatatccaa gaagcccagg cactttttga tcctttgagt agaaaattaa atgacggtgt
     8821 aggaaacagt gacgatacag atgaagaata caggtaaacg aattgatctg atagccaata
     8881 gaaaaccgca gagtcaaagg gttttgtatg aattgcgaga tcgtttgaag agaaatcagt
     8941 ttatactcaa tgataccaat ccggatattg tcatttccat tggcggggat ggtatgctct
     9001 tgtcggcctt tcataagtac gaaaatcagc ttgacaaggt ccgctttatc ggtcttcata
     9061 ctggacattt gggcttctat acagattatc gtgattttga gttggacaag ctagtgacta
     9121 atttgcagct agatactggg gcaagggttt cttaccctgt tctgaatgtg aaggtctttc
     9181 ttgaaaatgg tgaagttaag attttcagag cactcaacga agccagcatc cgcaggtctg
     9241 atcgaaccat ggtggcagat attgtaataa atggtgttcc ctttgaacgt tttcgtggag
     9301 acgggctaac agtttcgaca ccgactggta gtactgccta taacaagtct cttggcggtg
     9361 ctgttttaca ccctaccatt gaagctttgc aattaacgga aattgccagc cttaataatc
     9421 gtgtttatcg aacactgggc tcttccatta ttgtgcctaa gaaggataag attgaactta
     9481 ttccaacaag aaacgattat catactattt cggttgacaa tagcgtttat tctttccgta
     9541 atattgagcg tattgagtat caaatcgacc atcataagat tcactttgtc gcgactccta
     9601 gccataccag tttctggaac cgtgttaagg atgcctttat cggtgaggtg gatgaatgag
     9661 gtttgaattt atcgcagatg aacatgtcaa ggttaagacc tttttaaaaa agcacgaggt
     9721 ttctaaggga ttgctggcta agattaagtt tcgaggtgga gctattctgg tcaataatca
     9781 accgcaaaat gcaacgtatc tattggacgt tggagactac gttaccattg acattcccgc
     9841 tgaggaaggc tttgaaacct tggaggctat tgagcatcca ttagatattc tctatgagga
     9901 tgaccacttt ctagtcttga ataaacccta tggagtggct tctattccta gtgtcaatca
     9961 ctctaacacc attgccaatt ttatcaaggg ttactatgtc aagcaaaatt atgaaaatca
    10021 gcaggttcac attgttacca gactagatag ggacacttct ggcttgatgc tctttgccaa
    10081 gcacggttat gcccatgcac gattagacaa gcagttgcag aagaaatcta tcgagaaacg
    10141 ctactttgct ttggttaagg gagatggaca tttggagcca gaaggggaaa ttattgctcc
    10201 gattgcgcgt gatgaagatt ccattattac cagacgagtg gctaaaggcg gaaagtatgc
    10261 ccatacttca tacaagattg tagcttctta tggaaatatt cacttggtct atattcacct
    10321 gcacactggt cgaacccatc aaatccgagt ccatttttct catatcggtt ttcctttgct
    10381 gggagatgat ttgtatggtg gtagtctgga agatggtatt caacgtcagg ctctgcattg
    10441 ccattaccta tccttttatc atccattttt agagcaagac ttgcagttag aaagtccctt
    10501 gccggatgat ttcagtaacc ttattaccca gttatcaact aatactctat aaaaactgtc
    10561 tcagagtata attattatct taaaggagaa aactcatgga agtttttgaa agtctcaaag
    10621 ccaaccttgt tggtaaaaat gctcgtatcg ttctccctga aggggaagag cctcgtattc
    10681 ttcaagcaac aaaacgctta gtaaaagaaa cagaagtgat tcctgttttg cttggaaatc
    10741 ctgaaaaaat taaaatttat cttgaaattg aaggaatcat ggatggttat gaggtcatcg
    10801 accctcaaca ttatcctcaa tttgaagaaa tggtttctgc cttggtggag cgtcgcaagg
    10861 gcaaaatgac tgaagaagat gtacgcaagg ttttggttga agatgtcaac tactttggtg
    10921 tgatgttggt ttacttgggc ttggttgatg gaatggtgtc aggagcgatt cactcaacag
    10981 cttcaacagt tcgtccagct ctacaaatca tcaaaactcg tccaaatgta actcgtactt
    11041 caggagcctt cctcatggtt cgtggtacgg aacgttacct atttggagac tgtgccatta
    11101 acatcaatcc agatgcagaa gccttggctg aaattgccat caactcagca atcacagcta
    11161 agatgtttgg catcgaacct aaaattgcca tgttgagcta ttctactaaa ggttcagggt
    11221 ttggtgaaag cgttgataag gtcgttgaag caactaaaat tgctcacgac ttgcgtcctg
    11281 accttgaaat cgatggtgag ttgcaatttg atgcagcctt tgttcctgaa actgcagctc
    11341 tgaaagctcc tggaagtacg gtagctggtc aagcaaatgt cttcatcttc ccaggtatcg
    11401 aggccggaaa tatcggttac aagatggctg aacgcctggg tggctttgcg gctgtaggac
    11461 ctgttttgca aggtttaaac aagccagtta atgatctttc tcgtggatgt aatgcagatg
    11521 atgtttacaa gttgaccctc atcacagcag ctcaagcagt tcatcaatag tgaaaactat
    11581 aaagcgatat actatgctat actgtagtta tgaaactatg tacgaaaagc actgccatta
    11641 attcctgaga actaaattac tgattggtgt caaaaaggaa aacttccaag cgatgatatc
    11701 ctgtctatac acgacctata gaaatctgta atatgtatgt ccgtaaaacg ataatttccc
    11761 tttttgattt taaatgagta tgaaaagaga attttttcat gagaaaacgc ataatattaa
    11821 gtgtcttgac acctgctatt atgcgttttc tggctctttg tcaactgtag tgggttgaag
    11881 aaaagctaag ctcgagaaag gacaaatttt gtcctttctt ttttgatatt cagagcggta
    11941 aaaatccgtt ttttgaagtt ttcaaagttc cgaaaaccaa aggcattgcg cttgataagt
    12001 ttgatgagat tattggtcgc ttccaatttg gcgtttgaat ag
//
LOCUS       DAVBEO010000060        11774 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 009
            SAMEA1678075-rid20185393.denovo.060, whole genome shotgun sequence.
ACCESSION   DAVBEO010000060 DAVBEO010000000
VERSION     DAVBEO010000060.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678075
            Sequence Read Archive: ERR226392
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11774)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11774)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980207.1
            Genome Coverage       :: 150x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:50:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 72 of 147
            Pseudo Genes (incomplete)         :: 72 of 147
            Pseudo Genes (internal stop)      :: 42 of 147
            Pseudo Genes (multiple problems)  :: 32 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11774
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678075-rid20185393.denovo.060"
                     /strain="KS 009"
                     /db_xref="taxon:1313"
     gene            1..1048
                     /locus_tag="VQ543_001841"
                     /pseudo
     CDS             1..1048
                     /locus_tag="VQ543_001841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            complement(1164..1967)
                     /locus_tag="VQ543_001842"
     CDS             complement(1164..1967)
                     /locus_tag="VQ543_001842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fic/DOC family protein"
                     /protein_id="HET2612514.1"
                     /translation="MQSTYNIDNPNLSYEAKRDLWRIGFGLQKVDNLVPSAYMESLAE
                     KQSRGELTYEQVYEDATAYHHTIDASTEEADLVSLRIVELLSRRGFSFSPATLLAIHK
                     ELFQDIFEPSIPVGQFRQTNITKNEPVLNGESVVYSDYSMIQMTLDYDFNQEKQVAYA
                     TLTQADVVKQIQHFISGIWQIHPFREGNTRTVTVFLIQYLREFGFDIDNTPFQQHSKY
                     FRDALVLDNAKILQRRSEFLTAFFENLLLGGQNDLSSEKMYLDLDLDFS"
     gene            complement(2246..3001)
                     /locus_tag="VQ543_001843"
     CDS             complement(2246..3001)
                     /locus_tag="VQ543_001843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000033780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3883 domain-containing protein"
                     /protein_id="HET2612515.1"
                     /translation="MSKHPHYELLNLIGYGLAKFDKLFIKEFQCSSKSEFYRYVVSLG
                     IAETTGVVKNRMDLFDPYFDNNRKGWWQKAEVYRFRKDLIDMMFGNEDVHSYAEIVKM
                     LLASEGKKTGITIVEKPIVRTKFKRLQETGMEAENYFILHFDKEEKFQGGQLTDARLY
                     GDGYDFQVDVQEYSYLAEVKGIRKSKGRVRLTAKEFEKVKEFQSDFILSLVTNLDDIP
                     KLVLIDNPLKHFEFKKNIIKNEIIEYRSVEDLY"
     gene            complement(3071..5722)
                     /locus_tag="VQ543_001844"
     CDS             complement(3071..5722)
                     /locus_tag="VQ543_001844"
                     /EC_number="6.1.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009732359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="valine--tRNA ligase"
                     /protein_id="HET2612516.1"
                     /translation="MSKELSSKYNPAEVEAGRYQKWLDADVFKPSGDQKAKPYSIVIP
                     PPNVTGKLHLGHAWDTTLQDIIIRQKRMQGFDTLWLPGMDHAGIATQAKVEERLRGEG
                     ISRYDLGRESFLTKVWEWKDEYSTTIKEQWGKMGLSVDYSRERFTLDEGLSKAVRKVF
                     VDLYKKGWIYRGEFIINWDPAARTALSDIEVIHKDVEGAFYHMNYMLEDGSRALEVAT
                     TRPETMFGDVAVAVNPEDPRYKDLIGKNVILPIANKLIPIVGDEHADPKFGTGVVKIT
                     PAHDPNDFLVGQRHNLPQVNVMNDDGTMNELAFEFSGMDRFEARKAVVAKLEEIGALV
                     KIEKRVHSVGHSERTGVVVEPRLSTQWFVKMDQLAKNAIANQDTDDKVEFYPPRFNDT
                     FLQWMENVHDWVISRQLWWGHQIPAWYNEAGEIYVGEEAPAGDGWKQDEDVLDTWFSS
                     ALWPFSTMGWPNTETTDFKRYYPNSTLVTGYDIIPFWVSRMIFQGIEFTGKSPFKNAL
                     IHGLIRDEEGRKMSKSLGNGIDPMDVIDKYGTDSLRWFLSNGSAPGQDVRFSYEKMDA
                     SWNFINKIWNISRYILMNNEGLTLDVAHDNVTKVATGEAGNVTDRWILHNLNETIAKV
                     TENFDKFEFGVAGHILYNFIWEEFANWYVELTKEVLYSDNEEEKVITRSVLLYTLDKI
                     LRLLHPIMPFVTEEIFGQISEGSIVTAEYPTVNPAFEDLAAHTGVESLKDLIRAVRNA
                     RAEVNVAPSKPITILVKTSDSDLEAFFNSNVNYIKRFTNPEHLEIASTIPAPELAMSS
                     VITGAEIFLPLVDLLNVEEELARLEKELAKWQKELDMVGKKLSNERFVANAKPEVVQK
                     ERDKQADYQAKYDATVARIDEMKKLVK"
     gene            complement(5715..6293)
                     /locus_tag="VQ543_001845"
     CDS             complement(5715..6293)
                     /locus_tag="VQ543_001845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000550018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HET2612517.1"
                     /translation="MHLFIIGAPASGKMTIGQELSRLTDATLFYNHQAIDFALEIYQD
                     YTEEMWEFVRGITFSFLGASARNQRSVILTDVIDFSNQYQLMYLKQIQNLLDDYHQEI
                     LFVELETSLEECIRRNRTENRLKHKPLKRHIEVSEREILETAETLQLNSQYQPNELHH
                     YFKINNTNLSAEEAAKQIQNKINKIEKGHTHV"
     gene            complement(6293..6763)
                     /locus_tag="VQ543_001846"
     CDS             complement(6293..6763)
                     /locus_tag="VQ543_001846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000124546.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET2612518.1"
                     /translation="MARTELPDKIETERLVLRVRTVADAEDIFDYASLPEVAYPAGYG
                     IVVKGTDKIVGSVDFNHRHEDDVLEIGYTLHPDYWGRGYVPEAARALIDLAFKDLGLH
                     KIELTCFGYNLQSQRVAEKLGFTLEARIRDRKDAQGNCCDDLRYALLKSEWEVI"
     gene            complement(6750..7328)
                     /locus_tag="VQ543_001847"
     CDS             complement(6750..7328)
                     /locus_tag="VQ543_001847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavin reductase family protein"
                     /protein_id="HET2612519.1"
                     /translation="MKQSFKTNKLYYGFPVFILGYQDQNFGYNITTCSSSYSLGDWVV
                     IGVVARENAAEQIKQYQKFTVNISDETSMLAMEQAGFISHQEKLERLGVHYEISERTQ
                     TPILDACPLVLDCRVDRIVEEDGICHIFAKILERLVAPELLDEKGHFKNQLFAPTYFM
                     GDGYQRVYRYLDKRVDMKGSFIKKARKKDGKN"
     gene            complement(7611..8006)
                     /locus_tag="VQ543_001848"
     CDS             complement(7611..8006)
                     /locus_tag="VQ543_001848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase"
                     /protein_id="HET2612520.1"
                     /translation="MSKKLNRKKQLRNGLRRAGAFSSTVTKVVDETKKVVKRAEQSAS
                     AAGKAVSKKVEQAVEATKEQAQKVANSVEDFAANLGGLPLDRAKTFYDEGIKSASDFK
                     NWTEKELLALKGIGPATIKKLKENGIKFK"
     gene            complement(8102..8356)
                     /locus_tag="VQ543_001849"
     CDS             complement(8102..8356)
                     /locus_tag="VQ543_001849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000119704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1912 family protein"
                     /protein_id="HET2612521.1"
                     /translation="MSYEQEFMKEFEAWVNTQIMINDMAHKESQKVYEEDQDERAKDA
                     MIRYESRLDAYQFLLGKFENFKVGKGFHDLPEGLFGERNY"
     gene            complement(8365..9699)
                     /locus_tag="VQ543_001850"
     CDS             complement(8365..9699)
                     /locus_tag="VQ543_001850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000752887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF438 domain-containing protein"
                     /protein_id="HET2612522.1"
                     /translation="MTDEWIHILRDILLELHNGASPESVQDRFDATFTGVSAIEISLM
                     EHELMNSDSGVTFEDVMELCDVHANLFKNAIKGVEVLDTEHPGHPVRVFKEENLALRA
                     ALIRIRRLLDTYELMEDEEMLAEMRKGLVRQMGLVGQFDIHYQRKEELFFPIMERYGH
                     DSPPKVMWGVDDQIRELFQTALTTVKSLPEVSISSVKEAFEAFATEFESMIFKEESIL
                     LMILLESFTQDDWLQIAEESDAYGYAIIRPSEKWVPERQSFIEEKIAEEPVQLDTAEG
                     QVQQVIDTPEGHFTITFTPKEKEAVLDRHSQQAFGNGYLSVEQANLILNHLPMEITFV
                     NKEDIFQYYNDNTPADEMIFKRTPSQVGRNVELCHPPKYLDKVKTIMKRLREGSKDKY
                     EMWFKSESRGKFVHITYAAVHDEDGEFQGVLEYVQDIQPYREIDTDYFRGLE"
     gene            complement(9699..9932)
                     /locus_tag="VQ543_001851"
     CDS             complement(9699..9932)
                     /locus_tag="VQ543_001851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006144975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1858 domain-containing protein"
                     /protein_id="HET2612523.1"
                     /translation="MDNIIDVSIPVAEVVDKHPEVLEILVELGFKPLANPLMRNTVGR
                     KVSLKQGSKLTGTPMDKIVRTLEANGYEVIGLD"
     gene            9963..10037
                     /locus_tag="VQ543_001852"
                     /pseudo
     CDS             9963..10037
                     /locus_tag="VQ543_001852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829418.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            10026..10151
                     /locus_tag="VQ543_001853"
     CDS             10026..10151
                     /locus_tag="VQ543_001853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004238277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysyl-tRNA synthetase"
                     /protein_id="HET2612524.1"
                     /translation="MDRTDEVSNHTYSKVKLTWFEEIFEEYKMILLLILYHMERD"
     gene            complement(10201..10341)
                     /locus_tag="VQ543_001854"
     CDS             complement(10201..10341)
                     /locus_tag="VQ543_001854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000668195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2612525.1"
                     /translation="MKFFWTILAILFIKPIIGIVKFFWMIISFAVQLLFYKILDWFFK
                     LI"
     gene            complement(10338..10520)
                     /locus_tag="VQ543_001855"
     CDS             complement(10338..10520)
                     /locus_tag="VQ543_001855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001068155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2612526.1"
                     /translation="MNPIKAFAKIYGNYFLTVQGVKVMKTIKKDDHVVVGLGKLFIAD
                     KLMDTARWLIKPEERE"
     gene            complement(10522..11305)
                     /locus_tag="VQ543_001856"
                     /pseudo
     CDS             complement(10522..11305)
                     /locus_tag="VQ543_001856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840413.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
BASE COUNT         3522 a         2559 c         2177 g         3516 t
ORIGIN      
        1 acatgaaggc tggactaaag atagagtttc tcttgaatac tgcctcccaa gtcgtacgat
       61 acttcttaac tggctagcac aatacaggaa aaacgggtat actattgttg agaaaacaag
      121 agagagagta cctgagagcg gagaatgcca tcctaaaaaa gttaagagaa ctccgattga
      181 aggaggaaaa agagaaagaa gaaagacaga aattgttcaa gaattaatga ctgagttttc
      241 gttagatctt cttctaaaag ccattaaact agctcgttgg acctactact atcacttgaa
      301 acagctagac aaaacagata aggaccaaga gcttaaagct gaaattcaat ccatttttat
      361 cgaacacaag ggaaattatg cttatcgctg tgttcattta gaactaagaa atcgtggtta
      421 tctggtaaat cataaaagag ttcaaggctt gatgaaagta ctcaatttac aagctaaaat
      481 gcgacagaaa cgaaaataaa ggagacgttg gtaagaaggc agagaatctc attcaaggcc
      541 aatttgaagg atctaaaaca atggaaaagt gctacacaga tgtgactgaa tttgccattc
      601 cagcaagtac tcaaaagctt tacttatcac cagttttaga tggctttaac agcgaaatta
      661 tcgcctataa tctttcaact tcacccaact tagaacaagt acaaacaatg ttggaacagg
      721 cattcacaga gaagcactac gagaatacga ttctccatag tgaccaaggc tggcaatacc
      781 gacacgattc ttatcatcgg ttcctaagag taagggaatt caagcatcta tgtcacgcaa
      841 gggaaacagc caagacaacg gtatgatgga gtccttcttt gggattctga aatcggaaat
      901 gttttacggt tatgagaagt cgtttcagtc gcttaagcaa ttggaacaag ccattataga
      961 ctatattgat tactacaaca ataaacgaat taaggtaaaa ctaaaaggac ttagccttgt
     1021 gcaatacaga actaaatcct tcggataaat tatttgtcta actttttggg gtcagtacac
     1081 ctaaaacttt gatgatatac gttttcttgt gagaatattt acttcatttt tgcctaaaat
     1141 tcaatgttta ctcagtattt ggattatgaa aaatcgaggt ctaaatctag atacattttt
     1201 tctgaagaca aatcattttg accaccgagc aagagatttt caaaaaaagc tgttaaaaac
     1261 tcagaacgtc gctgtaaaat ctttgcatta tctaatacca aggcatcacg aaaatatttg
     1321 gaatgttgct gaaatggtgt attatcaata tcaaaaccaa actcacgaag atactgaatc
     1381 aaaaagaccg ttactgtccg agtgtttcct tcgcgaaatg gatgaatctg ccagattcct
     1441 gaaataaaat gctggatttg tttaaccaca tccgcctgag ttagtgtcgc atatgcaact
     1501 tgtttttcct gattaaaatc ataatctaag gtcatttgaa tcatggagta atcagagtac
     1561 acaacacttt caccattcaa aacaggttca ttctttgtga tattggtctg acgaaattgc
     1621 cccaccggaa tagagggttc aaatatatct tgaaacaact ccttatgaat agcaagtaag
     1681 gtcgcaggac taaagctaaa gcctcttcga gacaatagtt ctacaatacg tagagaaacc
     1741 aagtctgcct cttccgtact tgcatcaata gtatggtgat aagccgttgc atcctcataa
     1801 acctgctcat aagtcagttc tccccgggac tgtttctcag ccaaagattc catatacgct
     1861 gatggcacta gattgtcaac tttctgcaga ccaaaaccta tccgccataa atcacgcttc
     1921 gcttcataag acaagtttgg attgtcaatg ttgtaagttg attgcataga aatatccttt
     1981 caattgtttt tcttcattac cagtaaatca cgaaattggt tggaaactgg cttaaactat
     2041 aaaaagtcct cacaataggt tctatgatat atatatatat acttcatgta aataataaaa
     2101 gagttataat cagcactact gataaattca ataccgattt cgccatctta aaacttagtc
     2161 aaacgaatac cgttgatttc cagttcatta agtcgttgac ctgtcaagac ttctcgttcc
     2221 ttcaactgga aaagttaagg gggaactaat acaaatcctc tacgcttcta tattcaatga
     2281 tttcattttt gataatattc tttttaaact caaaatgttt taaaggatta tcgattaaca
     2341 ctaactttgg aatatcatct agatttgtga ccaaggataa aataaaatcc gattgaaact
     2401 ccttgacttt ttcaaattct tttgcagtta aacgcacacg ccccttagat tttcggatac
     2461 cttttacttc ggcaaggtaa gaatactctt ggacatctac ctgaaagtca tatccatcac
     2521 cataaagacg ggcatcggtt aactgtccac cttggaattt ttcttcttta tcaaaatgaa
     2581 ggataaaata attctcagcc tccattcccg tttcctgtag acgtttgaat ttagttcgaa
     2641 ctattggttt ttcaacgatg gttatgcctg ttttcttccc ttcactggca agtaacattt
     2701 taactatttc agcataacta tgaacatctt catttccaaa catcatatca attaaatctt
     2761 tacgaaaacg ataaacttca gctttctgcc accaaccttt tcgattattg tcaaaataag
     2821 gatcaaataa atccattcta ttttttacaa ctccagttgt ttcagcaatt cccagagaaa
     2881 ccacatagcg ataaaactcc gacttgctag agcattgaaa ttcttttata aaaagcttgt
     2941 caaacttggc aagaccgtag ccaattaaat ttaacaattc ataatgaggg tgtttggaca
     3001 tcactttctc catcaataga tattgatttc attataccaa aaaacacggc tcatcaccgt
     3061 gtttctgtgt ttatttcacc aacttcttca tctcatcaat acgtgctacg gtcgcatcat
     3121 acttagcttg gtaatctgct tgcttgtcgc gttctttttg gacaacttct ggtttagcgt
     3181 tggcgacgaa gcgttcgttg ctgagttttt tgccaaccat gtcgagttct ttctgccatt
     3241 tggcaagttc tttttccaga cgtgccaatt cttcttcgac attcaagagg tctaccagtg
     3301 gcaagaagat ttcggctcct gtgatgacgc ttgacatagc cagttcaggt gcagggatgg
     3361 ttgatgcgat ttccaagtgt tcaggatttg tgaaacgttt gatgtagttg acattgctgt
     3421 taaagaaggc ttccaagtcg ctatcgcttg tcttaacaag gatagtgata ggcttgcttg
     3481 gagcaacgtt tacttccgca cgcgcattac gaacggcacg gatcaagtct ttaaggcttt
     3541 ccacaccagt gtgagcagca aggtcttcaa aggctgggtt gacagttggg tattctgctg
     3601 taacgataga tccttctgag atttgtccaa agatttcctc tgtcacaaat ggcatgattg
     3661 ggtgaaggag acgaaggatc ttgtccaaag tgtatagtag aacagaacgt gtgatgactt
     3721 tctcttcttc gttatcgcta taaaggactt ccttggtcaa ctcaacatac cagttggcaa
     3781 attcttccca gatgaagttg taaaggatat gaccagccac accaaactcg aacttatcaa
     3841 agttttcagt aacttttgca atggtttcgt tgagattgtg gagaatccag cggtccgtca
     3901 cattaccagc ctcacctgtt gcaacttttg tgacattgtc atgcgccaca tccagcgtca
     3961 aaccttcatt gttcatgagg atatagcgag aaatgttcca aattttgtta ataaagttcc
     4021 atgaagcatc cattttctcg taagagaaac gaacgtcttg accaggagct gagccgtttg
     4081 acaagaacca acgaagacta tctgtaccat atttatcaat aacatccatt gggtcaatgc
     4141 catttccaag agatttagac atcttacgtc cttcttcatc acgaattaga ccatggataa
     4201 gagcattttt aaatgggctc tttcctgtaa attcaattcc ttggaaaatc atgcgtgata
     4261 cccagaaagg aataatatca tagcctgtta cgagtgttga atttggatag tagcgtttaa
     4321 agtcagtagt ttcggtatta ggccagccca tggttgagaa gggccagagg gcagagctga
     4381 accaagtgtc aaggacatct tcgtcctgtt tccagccatc gcccgctggg gcttcctcgc
     4441 cgacatagat ttcgcctgct tcattatacc aagcagggat ttggtgaccc caccagagct
     4501 gacgggaaat cacccagtcg tggacatttt ccatccattg caggaaggtg tcgttgaagc
     4561 gcggtgggta aaattccacc ttgtcatctg tgtcttggtt ggcaatggcg ttcttggcca
     4621 attggtccat cttgacgaac cattgagtag acaagcgtgg ctcaactacg acacctgtcc
     4681 gttctgagtg accgactgaa tggacacgtt tttcgatttt gacaagggca ccgatttctt
     4741 ccaacttagc aacgactgcc ttacgagctt caaaacgatc catgcctgaa aattcaaagg
     4801 caagctcgtt catagttccg tcgtcgttca tgacgttgac ttgtggcaag ttatgacgtt
     4861 ggccaaccaa gaagtcattt ggatcgtggg caggtgtgat tttcacgaca ccagtaccaa
     4921 acttaggatc tgcgtgctca tcaccaacga ttgggattaa tttattagca attggaagga
     4981 tgacattttt accaatcaag tccttgtagc gcgggtcttc tgggttgacc gcaaccgcaa
     5041 cgtccccaaa catggtctca ggacgagttg tagcaacttc aagggcgcgt gaaccatctt
     5101 ccagcatgta attcatgtga tagaaggcac cttcgacgtc cttgtgaata acctcgatat
     5161 cagaaagggc tgtgcgagct gctgggtccc agttgatgat aaactcacca cggtagatcc
     5221 agcctttctt gtaaaggtcc acaaagacct tacgaacagc ttttgacaaa ccttcgtcaa
     5281 gagtgaaacg ctcacgagag tagtctacag agagccccat cttgccccat tgttccttga
     5341 tagtagtgga atattcgtct ttccattccc agactttcgt caagaaagac tcacgaccaa
     5401 ggtcatagcg ggaaatgccc tcaccacgca agcgctcctc taccttagcc tgagtggcaa
     5461 tccctgcgtg gtccatccca ggaagccaaa gggtatcaaa accttgcatg cgtttttgac
     5521 ggatgataat atcttgcaaa gttgtatccc aagcgtgacc aaggtgaagt ttacctgtaa
     5581 cgtttggtgg tggaataacg attgaataag gcttagcctt ttgatcgcct gaaggcttga
     5641 aaacatcagc atcaagccat ttttggtaac gaccagcctc aacctcggct ggattgtatt
     5701 tagatgaaag ttctttagac atgtgtgtgt cctttctcta ttttgtttat tttattttga
     5761 atttgcttag cagcttcttc tgcagacaaa ttcgtattat ttattttaaa gtagtggtgc
     5821 aactcattcg gttgatattg ggaatttaat tgaagtgttt cagcggtctc taaaatttct
     5881 ctttcagata cctcaatatg tcgttttaag ggtttgtgct ttaatcgatt ctccgttcga
     5941 tttcgacgta tgcactcttc aagacttgtt tccaactcaa caaaaagaat ctcttgatga
     6001 taatcatcca acaaattctg aatttgcttt aaatacatca gttgatactg atttgaaaaa
     6061 tcaattacat ctgttaaaat tactgatcgc tgatttcttg cacttgctcc aaggaatgaa
     6121 aaagtgattc cacgaacaaa ttcccacatt tcctctgtat agtcctgata gatttctagt
     6181 gcaaaatcaa tggcttgatg gttataaaat agggtagcat ccgtcagtcg agataattct
     6241 tgaccaatgg tcatttttcc tgatgctgga gcaccaatga tgaaaagatg catcaaatca
     6301 cctcccactc actcttcagc aaggcatatc tcaaatcatc acagcagttg ccttgagcat
     6361 ctttacggtc tcttatgcga gcttcgaggg taaagccaag cttttccgcg actcgttgac
     6421 tttgaaggtt atatccaaag caagttagtt caatcttgtg aagacccaaa tctttaaagg
     6481 ctaagtcaat caaggcacgc gcagcttctg gcacataacc tcgcccccaa tagtctgggt
     6541 gtaaggtata gccgatttcc agcacatcat cttcatggcg atggttgaaa tcgacagagc
     6601 caacgatctt atccgttcct ttgacgacaa tcccgtagcc tgctggatag gcgacctctg
     6661 gcaaactagc atagtcaaag atatcctcag catccgccac agtacggact cgtaaaacga
     6721 gacgttctgt ttcgatttta tctggcagct cagttcttgc catccttctt cctcgctttt
     6781 ttgatgaaac tgcccttcat atctacacgc ttatccagat agcgataaac gcgctgatat
     6841 ccatctccca tgaaataggt tggggcaaac agttgatttt taaaatgtcc cttttcatcc
     6901 aggagttctg gggcaacaag tcgctcaaga atcttggcaa agatgtggca aataccgtct
     6961 tcctcaacaa tcctatctac ccgacaatct aaaacaagtg gacaggcgtc taaaatagga
     7021 gtctgagttc gttcagaaat ttcataatgc actcccaaac gttccaattt ctcctgatga
     7081 ctgataaaac cagcctgctc catcgcaagc atagaagttt catcagaaat attcacagta
     7141 aatttttgat actgtttgat ctgctctgcg gcattctctc tcgcaacgac tccaatcaca
     7201 acccaatctc ctagactata cgaggaacta caggtcgtga tgttatagcc aaaattctga
     7261 tcttgatatc ctaaaataaa aacaggaaaa ccataatata gtttattagt tttaaatgat
     7321 tgttttataa caacctcctt tgactaagac acaaaagaaa agccctgcca tctacatgac
     7381 agggacgaat gtatttatcc gcggtaccac ccaatttcgg gccaagcccg catctttagt
     7441 ctttaaaata aaaagacaga aatatttcat tttttcagtc attagcaacc agttttgaca
     7501 catttgtgga cttctcagcg ccgccacttt ctgtaaaatg tgggattcaa aacacctcta
     7561 atagctctat tgtagcaagt ttttctcgga aatgcaaggc tcaagaaaaa ttacttgaac
     7621 ttgatgccat tttctttcaa tttcttgatg gtagctgggc cgattccttt caaggcaagg
     7681 agttcttttt cagtccagtt tttgaaatct gaagcagact tgattccttc atcatagaaa
     7741 gtcttggcac gatcaagtgg aagtccaccc aagtttgctg caaaatcttc tacagaatta
     7801 gctacttttt gagcttgctc tttggtagct tctactgctt gttcaacttt tttagaaaca
     7861 gccttaccag ctgcgcttgc tgactgttct gcacgcttca cgactttttt tgtctcatct
     7921 acaaccttag tcacagtact tgaaaaggca cctgcgcgac ggaggccatt tcgtaattgt
     7981 tttttacgat tgagtttctt tgacatgata aaatcctttc aataaaaaat ccctgctctg
     8041 acaaggattt aacataaaca ttctatcaag attttagtga aaaatcaaga atctttctcg
     8101 tttaataatt tcgctcacca aacaagcctt ctggcaaatc atggaatccc ttgcctactt
     8161 tgaagttttc aaacttacca agcaagaact gataagcatc caagcgactc tcgtagcgaa
     8221 tcatggcatc tttggcacgc tcgtcctggt cttcttcgta aactttttga ctttccttgt
     8281 gcgccatgtc gttaatcatg atttgggtat tgacccaagc ttcaaattcc ttcataaatt
     8341 cttgttcgta actcattttt ctccttattc taatccacga aaatagtccg tatcaatctc
     8401 acggtagggc tggatatcct gaacatactc caacactcct tggaattctc cgtcttcatc
     8461 gtgtactgca gcataggtga tgtggacaaa cttacctcgc gactcagact tgaaccacat
     8521 ttcatacttg tctttgcttc cctcacgaag cctcttcatg atagttttga ccttgtccaa
     8581 gtacttaggc ggatggcaga gttcgacatt gcgcccgact tgagacggcg tccgtttgaa
     8641 aatcatctca tcagctggcg tattgtcatt gtaatactgg aaaatatctt ctttattgac
     8701 aaaggtaatc tccataggga gatgattgag gatgagattg gcctgctcga ctgaaagata
     8761 gccattacca aaagcctgtt gactatggcg gtccagcaca gcttcctttt ccttaggggt
     8821 aaaggtaatg gtaaaatggc cttctggcgt atctatgact tgttgaactt gaccttctgc
     8881 cgtatctagc tgtacaggct cctctgcaat cttttcctca ataaagctct gtcgttctgg
     8941 cacccatttc tctgacggac ggatgatggc atagccatag gcatcgctct cctccgcaat
     9001 ctgaagccag tcatcctgag taaaagactc aaggagaatc atgaggagga tggactcttc
     9061 cttgaaaatc atactttcaa actctgtcgc aaaagcttca aaagcttcct ttacactgct
     9121 aattgacact tctggtagtg acttgactgt cgttagagct gtttgaaaga gttccctaat
     9181 ctgatcatcc actccccaca taactttggg aggtgaatcg tgtccatagc gctccatgat
     9241 aggaaagaag agttcttcct tacgttggta atggatgtca aattgcccca caagccccat
     9301 ctgacgcacc aagcccttgc gcatctccgc aagcatttcc tcgtcttcca tcaactcata
     9361 ggtatctaac aatctacgaa tgcgaatcaa agctgcacgg agggccaaat tttcttcctt
     9421 aaagacacga actgggtgcc cagggtgttc ggtatctaaa acttcgacac ctttgatagc
     9481 atttttaaaa agattggcat ggacatcaca gagttccata acatcttcaa aagtgacgcc
     9541 cgaatccgag ttcatcagct cgtgctccat aagggaaatc tcgatggctg acacgcccgt
     9601 aaaggtcgca tcaaagcgat cttgaaccga ctcaggagag gcgccattgt gcaattctaa
     9661 caaaatatcc cgtaggatat gaatccattc atctgtcatt agtctaatcc aatcacttcg
     9721 tagccattcg cttccagtgt gcgtacaatc ttgtccatag gagttcctgt tagcttagaa
     9781 ccctgtttaa gtgatacttt acgaccaact gtattgcgca ttaagggatt ggcaaggggt
     9841 ttaaaaccca actccactag aatttccaag acttctggat gcttgtccac cacttctgca
     9901 acaggaattg acacatcgat gatattgtcc atgacgacct ccattgtatg ttctaatact
     9961 caatgaaaat caaagagcaa actaggaagc tagccgcagg ttgctcaaaa cagtgttttg
    10021 aggttgtgga tagaactgac gaagtcagta accataccta cagcaaggtg aagctgacgt
    10081 ggtttgaaga gattttcgaa gagtataaaa tgattttact gcttatatta taccatatgg
    10141 agagagatta aaaaactagc agtggagttc ctgctagttt tctgcgactt ggattaccat
    10201 ctagataagt ttaaagaacc aatccaatat cttgtaaaac agcaattgaa ctgcaaaaga
    10261 aatgatcatc caaaagaatt tcacaatccc aataatcggt ttgataaaaa gaatagcaag
    10321 aattgtccag aaaaatttca ttctctctcc tctggcttaa tgagccaccg agccgtatcc
    10381 attagcttat ctgcaataaa gagttttccc agaccaacaa cgacatggtc atctttcttt
    10441 atcgttttca tcacttttac accttgcacg gtcaaaaagt aattaccata aattttagca
    10501 aaagctttga taggattcat attattctcc tttgatgatt tcagcctctt ttcggattgt
    10561 ttcaacatct tcttgatatt gaacttcact atagttgact agcttggata attctttctg
    10621 caagctttcc cccattggtt tcatagttgc aaaggttaaa ccacctgaaa tgataccacc
    10681 caagatagga ataaatttcc ccattccttt ggccaaccct cccttggtaa gattcacacc
    10741 aaatattttt aagacttttt tcaaaatagg gtaccaaagc gtctttgtta aagctttatt
    10801 aggcactgtt ttcattacct gtttggcaat tgttatacca ccagcacgta gcaaacaaag
    10861 cagcggttcc attcacccct aacattacgc ctagataaag caagagggta ttttgagcat
    10921 cttcactcaa ctcctcacgt gaagcccaaa gatcctcata accataaata taacctaatt
    10981 cttgggccaa tttcagagag aaaccataaa attgagccac ataagctgga atggtaattg
    11041 ccatagcaag ccctccaggt aatcctgcca aaacagaagt cccactcgct aataaaacat
    11101 tatccctaat acaggcatta gccactcgat ctaagatttc ttgagataag agagacgttg
    11161 gaccttgttc caataaggta ggaatgtcct gtggacccaa ttctttggaa aacttatcca
    11221 ctaaaaattt cgaacgatca accttaacaa ctggtagttt taccacttgt tgtaatactt
    11281 gcatagctaa gtcttgttca gccatataca aactccttat ttcttttttg caccttatca
    11341 tattatattt cctacaaaaa aagcattttc taattagata acattaaaaa atacagaacc
    11401 ccttttttat agtaaaataa aacaagaaca ggacaaatcg atcaggacag tcaaatcgat
    11461 ttctaacaat gttttagaag tagaggcgta ctattctagt ttcaatatat tttaaaagaa
    11521 tatttttcca tttcaaattc aacctatttt cctccaccaa aaaagggctc tataatattt
    11581 gtagtgggta aattccctat ggatattatg gagcctattt ttgtgtagaa aaaaagtccc
    11641 atatgaccta taatgaaaag cgacaaaaca actcattaga aagaatcata tggaacaatt
    11701 acattttatc acaaaactgc tcgatattaa agacccaaac atcaagattc tagatatcat
    11761 caataaagat acac
//
LOCUS       DAVBEO010000061        11401 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 009
            SAMEA1678075-rid20185393.denovo.061, whole genome shotgun sequence.
ACCESSION   DAVBEO010000061 DAVBEO010000000
VERSION     DAVBEO010000061.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678075
            Sequence Read Archive: ERR226392
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11401)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11401)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980207.1
            Genome Coverage       :: 150x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:50:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 72 of 147
            Pseudo Genes (incomplete)         :: 72 of 147
            Pseudo Genes (internal stop)      :: 42 of 147
            Pseudo Genes (multiple problems)  :: 32 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11401
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678075-rid20185393.denovo.061"
                     /strain="KS 009"
                     /db_xref="taxon:1313"
     gene            complement(<1..947)
                     /locus_tag="VQ543_001857"
     CDS             complement(<1..947)
                     /locus_tag="VQ543_001857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001083019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HET2612527.1"
                     /translation="MNRYAVQLISRGAINKMGNMLYDYGNSVWLASMGTIGQTVLGMY
                     QISELVTSILVNPFGGVISDRFSRRKILMTADLVCGILCLAISFIRNDSWMIGALIVA
                     NIVQVIAFAFSRTANKAIITEVVEKDEIVIYNSRLELVLQVVGVSSPVLSFLVLQFAS
                     LHMTLLLDSLTFFIAFILVTFLPKEEAKVQEKKAFTGRDIFVDIKDGLHYIWHQQEIF
                     FLLLVASSVNFFFAAFEFLLPFSNQLYGSEGAYASILTMGAIGSIIGALLASKIKANI
                     YNLLILLALTGVGVFMMGLPLPTFLSFSGNLVCELFMTI"
     gene            complement(1027..1890)
                     /locus_tag="VQ543_001858"
     CDS             complement(1027..1890)
                     /locus_tag="VQ543_001858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012291596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE/MutR family transcriptional regulator"
                     /protein_id="HET2612528.1"
                     /translation="MEHLGKVFREFRTSGNYSLKEAAGESCSTSQLSRFELGESDLAV
                     SRFFEILDNIHVTIENFMDKARNFHNHEHVSMMAQIIPLYYSNDIAGFQKLQREQLEK
                     SKSSTTSLYFELNWILLQGLICQRDASYDMKQDDLDKVADYLFKTEEWTMYELILFGN
                     LYSFYDVDYVTRIGREVMEREEFYQEISRHKRLVLILALNCYQHCLEHSSFYNANYFE
                     AYTEKIIDKGIKLYERNVFHYLKGFALYQKGQCKEGCKQMQEAMHIFDVLGLPEQVAY
                     YQEHYEKFVKS"
     gene            complement(1893..3794)
                     /locus_tag="VQ543_001859"
     CDS             complement(1893..3794)
                     /locus_tag="VQ543_001859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000584877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HET2612529.1"
                     /translation="MIILQANKIERSFAGEVLFDNINLQVDERDRIALVGKNGAGKST
                     LLKILVGEEEPTSGEINKKKDISLSYLAQDSRFESENTIYDEMLHVFNDLRRTERQLR
                     QMELEMGEKSGEDLDKLMSDYDRLSENFRQAGGFTYEADIRAILNGFKFDESMWQMKI
                     AELSGGQNTRLALAKMLLEKPNLLVLDEPTNHLDIETISWLENYLVNYSGALIIVSHD
                     RYFLDKVATITLDLTKHSLDRYVGNYSRFVELKEQKLATEAKNYEKQQKEIAALEDFV
                     NRNLVRASTTKRAQSRRKQLEKMERLDKPEAGKKAANMTFQSEKTSGNVVLTVENAAV
                     GYDGEVLSQPINLDLRKMNAVAIVGPNGIGKSTFIKSIVDQIPFIKGEKRFGANVEVG
                     YYDQTQSKLTPSNTVLDELWNDFKLTPEVEIRNRLGAFLFSGDDVKKSVGMLSGGEKA
                     RLLLAKLSMENNNFLILDEPTNHLDIDSKEVLENALIDFDGTLLFVSHDRYFINCVAT
                     HVLELSENGSTLYLGDYDYYVEKKATAEMSQTEEASTSNQAKEASPVNDYQAQKESQK
                     EVRKLMRQIESLEAEIEELESQSQAISEQMLETNDADKLMELQAELDKISHRQEEAML
                     EWEELSDQV"
     gene            complement(4222..4497)
                     /locus_tag="VQ543_001860"
     CDS             complement(4222..4497)
                     /locus_tag="VQ543_001860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002950996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HET2612530.1"
                     /translation="MANKQDLIAKVAEATELTKKDSAAAVEAVFAAVADYLAAGEKVQ
                     LIGFGNFEVRERAERKGRNPQTGKEMTIAASKVPAFKAGKALKDAVK"
     gene            complement(4603..5442)
                     /locus_tag="VQ543_001861"
     CDS             complement(4603..5442)
                     /locus_tag="VQ543_001861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000161411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HET2612531.1"
                     /translation="MTKIKIVTDSSVTIEPELVKQLDITIVPLSVMIDNVVYSDADLK
                     EEGKFLQLMQESKNLPKTSQPPVGVFAEIFEDLCKDGGQILAIHMSHALSGTVEAARQ
                     GASLSTADVIVVDSSFTDQALKFQVVEAAKLAQEGKDMEAILSHVEEVKNHTELYIGV
                     STLENLVKGGRIGRVTGLLSSLLNIRVVMQMKDHELQPMVKGRGTKTFKKWLDELITS
                     LSERAVAEIGISYSGSDDWAKEMKESLQAYVEKPISVLETGSIIQTHTGENAWAILIR
                     YHS"
     gene            5584..6432
                     /locus_tag="VQ543_001862"
     CDS             5584..6432
                     /locus_tag="VQ543_001862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000592058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HET2612532.1"
                     /translation="MIKKIYPIFTILLGAAIYAFGLTYFVVPHHLFEGGATGITLITF
                     YLFKIPVSLMNLLINIPLFILAWKIFGAKSLYSSLLGTLALSGWLAFFEHIPLHIDLQ
                     GDLLITALIAGILLGIGLGIIFNAGGTTGGTDILARILNKYTHISIGKLLFILDFCIL
                     MLILLIFKDLRLVSYTLLFDFIVSRVIDLIGEGGYAGKGFMIITKRPDQLAKAINDDL
                     GRGVTFISGQGYYSKENLKIIYCIVGRNEIVKTKEMIHRIDPQAFITITEAHEILGEG
                     FTFEKE"
     gene            complement(6525..7442)
                     /locus_tag="VQ543_001863"
     CDS             complement(6525..7442)
                     /locus_tag="VQ543_001863"
                     /EC_number="2.7.1.26"
                     /EC_number="2.7.7.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000587449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional riboflavin kinase/FAD synthetase"
                     /protein_id="HET2612533.1"
                     /translation="MIITIPIKNQKDIGTPSDSVVVLGYFDGIHKGHQELFRVANKAA
                     RKDLLPIVVMTFNESPKIALEPYHPDLFLHILNPAERERKLKREGVEELYLLDFSSQF
                     ASLTAQEFFATYIKAMNAKIIVAGFDYTFGSDKKTAEDLKDYFDGEVIIVPPVEDEKG
                     KISSTRIRQAILDGNVKEAGKLLGAPLPSRGMVVHGNARGRTIGYPTANLVLLDRTYM
                     PADGVYVVDVEIQRQKYRAMASVGKNVTFDGEEARFEVNIFDFNQDIYGETVMVYWLD
                     RIRDMTKFDSVDQLVDQLKADEEVTRNWS"
     gene            7879..8084
                     /locus_tag="VQ543_001864"
                     /pseudo
     CDS             7879..8084
                     /locus_tag="VQ543_001864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844775.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
     gene            complement(8395..8688)
                     /gene="rpmA"
                     /locus_tag="VQ543_001865"
     CDS             complement(8395..8688)
                     /gene="rpmA"
                     /locus_tag="VQ543_001865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L27"
                     /protein_id="HET2612534.1"
                     /translation="MLKMTLNNLQLFAHKKGGGSTSNGRDSQAKRLGAKAADGQTVTG
                     GSILYRQRGTHIYPGVNVGRGGDDTLFAKVEGVVRFERKGRDKKQVSVYPIAK"
     gene            complement(8705..9049)
                     /locus_tag="VQ543_001866"
     CDS             complement(8705..9049)
                     /locus_tag="VQ543_001866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal-processing cysteine protease Prp"
                     /protein_id="HET2612535.1"
                     /translation="MIQAVFERAEDGELRGAEITGHAESGEYGLDVVCASVSTLAINF
                     INSIEKFAGYEPILELNEDEGGYLMVEIPKDLPSHQREMTQLFFESFFLGMANLSENY
                     SEFVQTRVITEN"
     gene            complement(9065..9379)
                     /gene="rplU"
                     /locus_tag="VQ543_001867"
     CDS             complement(9065..9379)
                     /gene="rplU"
                     /locus_tag="VQ543_001867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L21"
                     /protein_id="HET2612536.1"
                     /translation="MSTYAIIKTGGKQVKVEVGQAVYIEKLNVEAGQEVTFNEVVLVG
                     GENTVVGTPLVAGATVVGTVEKQGKQKKVVTYKYKPKKGSHRKQGHRQPYTKVVINAI
                     NA"
     misc_feature    complement(9415..9502)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00559"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L21 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00559"
     gene            complement(9597..10196)
                     /locus_tag="VQ543_001868"
     CDS             complement(9597..10196)
                     /locus_tag="VQ543_001868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001858962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1275 domain-containing protein"
                     /protein_id="HET2612537.1"
                     /translation="MTFCAGYVDAYTFIVRGNTLVAGQAGNVVFLSVELIQNNVSDVR
                     DKLLTLITFIMGVFLLTIYKEKLRIVKKPILSLIPLAILSIIIGFVPQTVDNIYLVQP
                     LAFCMGLVTTAFGEVSGIAYNNAFMTGNIKRTMLAFGDYFRTKHTPFLREGFIFVSLL
                     SSFVLGDVFSAYLTIFYHEKTILGVPIMMSIFYLSMLFA"
     gene            10666..10965
                     /locus_tag="VQ543_001869"
     CDS             10666..10965
                     /locus_tag="VQ543_001869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaB/EbfC family nucleoid-associated protein"
                     /protein_id="HET2612538.1"
                     /translation="MMNMQNMMRQAQKLQKQMEQSQAELAAMQFVGKSAQDLVQATLT
                     GDKKVVSIDFNPAVVDPEDLETLSDMTVQAINSALEQIDETTKKKLGAFAGKLPF"
     gene            11184..>11401
                     /locus_tag="VQ543_001870"
     CDS             11184..>11401
                     /locus_tag="VQ543_001870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET2612539.1"
                     /translation="MGQLHFITKLLDIKDPNIQILDIINKDTHKEIIAKLDYDAPSCP
                     ECGSQMKKYDFQKPSKIPYLETTGMPTR"
BASE COUNT         3615 a         2365 c         1895 g         3526 t
ORIGIN      
        1 aaaatcgtca taaacaattc acaaactaaa tttccagaaa aggaaagaaa agttggaagt
       61 ggtaatccca tcataaaaac tccgacacct gtcaaagcca gtaaaatcaa aagattataa
      121 atattagctt taattttact agctagaaga gccccaatga tggaaccaat agcccccata
      181 gttaaaatac ttgcataggc tccttctgac ccgtaaagct gattcgaaaa gggaagtaga
      241 aattcaaaag ctgcaaaaaa gaaattaacg ctggaagcta ccagcaaaag gaagaaaatt
      301 tcttgctgat gccagatata gtgtaaccca tccttgatat ctacaaaaat atctctccca
      361 gtaaaagcct ttttctcttg aacttttgct tcctcttttg gaaggaaagt cactagaata
      421 aaagcaatga aaaaagtcag cgagtctagc agtagcgtca tatggagact tgcaaactgt
      481 aaaacaagga aggaaagaac aggagagcta acacctacaa cctgcaaaac cagctctaag
      541 cgagaattat agatcacaat ctcatctttc tccaccactt cagttatgat agctttattg
      601 gctgtgcgag aaaaggcaaa agcaataacc tgcacaatgt tagcaacaat caaagcgcca
      661 atcatccagc tatcattcct tatgaaagaa atagccagac aaagaatccc acaaacaaga
      721 tctgccgtca ttaaaatctt acgacgagaa aaacggtctg aaataactcc gccaaaggga
      781 ttgacgagaa tagatgtgac gagctcagaa atctgataca ttcctaaaac tgtctgtcct
      841 atagtcccca tagaagccaa ccagacacta tttccataat catagagcat atttcccatt
      901 ttattgatag ccccacggct aatcaactgc actgcatagc gattcatatt aaagctcctc
      961 tcaaattttg aaactattgt atcaaaaccg aaaggagctt tttatttttt cccttatttg
     1021 ggaaaattaa cttttgacaa atttttcgta gtgttcctga taataggcta cttgctctgg
     1081 aagacctaac acatcaaaaa tatgcatggc ctcttgcatc tgcttacagc cttctttaca
     1141 ctgtcctttt tgatataagg caaaaccttt taaataatgg aaaacattac gctcataaag
     1201 cttaatacct ttgtcaataa tcttctctgt ataagcctca aaatagttgg cattataaaa
     1261 agaagaatgc tctaaacaat gctggtaaca attgagggcc aaaatcaaca ctaatctctt
     1321 atggcgacta atctcttggt aaaattcctc cctctccata acttctctac caatccgagt
     1381 gacatagtct acatcgtaga aactatagag gttaccgaaa agaatcaact catacatggt
     1441 ccattcttct gttttgaaga gataatctgc taccttatcc aaatcatcct gcttcatatc
     1501 ataactcgca tctctttgac aaatcagacc ttgtagcaaa atccagttca gctcaaaata
     1561 aagggaagtc gtcgaactct tagacttttc aagttgttct ctttgaagct tttgaaaacc
     1621 tgcaatatcg tttgaatagt aaagtgggat aatctgtgcc atcatagaca catgttcatg
     1681 attatgaaaa ttccttgcct tatccatgaa attttcgatt gttacatgaa tgttatccaa
     1741 aatctcaaag aaacgggaga ctgccaggtc agactcccca agctcaaagc gagataactg
     1801 agaggtagag caggattcgc ctgctgcttc ctttaaagaa taatttccac ttgttcgaaa
     1861 ttcacgaaat acttttccaa gatgttccat ctttacacct gatctgataa ttcttcccac
     1921 tcaagcatag cttcttcctg acgatggctg attttatcca gctcagcctg taattccatg
     1981 agtttgtcgg catcgtttgt ttccaacatt tgttcagaaa tggcttggct ttgactttct
     2041 agctcttcaa tttcagcttc tagactttcg atttgtcgca tgagtttgcg aacttctttt
     2101 tgactttctt tctgggcctg atagtcattg actggacttg cttcctttgc ttgattgcta
     2161 gttgaagctt cctcagtctg actcatttct gctgttgctt tcttctcaac atagtagtcg
     2221 taatctccaa ggtagagagt tgaaccattc tcagacaatt ccaaaacatg agttgccaca
     2281 caattgataa agtaacgatc atgactgaca aaaagcaagg taccatcaaa gtcaatcaag
     2341 gcattttcta gcacttcctt actatcaata tccaagtggt tggtcggctc atccagaatc
     2401 aaaaagttat tgttttccat agacaattta gctaaaagca aacgagcttt ttcgccacca
     2461 gatagcatgc cgactgattt tttaacatca tctcctgaga aaaggaaggc tccaagacgg
     2521 ttgcggattt caacttctgg tgtcaatttg aaatcattcc agagttcatc cagcaccgta
     2581 ttacttggtg tcagcttgct ttgggtttgg tcatagtaac caacctcaac attagcgcca
     2641 aagcgctttt ctcccttgat aaacggaatt tgatccacga ttgatttgat aaaggttgat
     2701 tttccgatac cattgggacc aacgatagca acagcattca tcttacgaag gtctaggtta
     2761 atcggttgtg acaggacttc cccatcatag ccaacagccg cattttcaac agtcaaaaca
     2821 acattgcccg acgttttttc agactggaag gtcatgttgg ctgctttctt gccagcttcc
     2881 ggcttgtcca aacgctccat tttttctagt tgtttacggc gagattgagc acgtttggtc
     2941 gttgaagcac gaactagatt gcgattgaca aagtcttcca gagcagcgat ttccttctgt
     3001 tgcttttcat agttttttgc ctcagtagct agcttttgct ccttcaactc gacaaaacga
     3061 gagtaattcc ccacatagcg atccaaggaa tgcttggtca aatctagcgt aattgtcgca
     3121 accttgtcca agaaataacg gtcgtggctg acgataatga gggcaccgct atagtttacc
     3181 aagtaattct ctagccagga gatggtttca atatccaagt ggttagttgg ctcgtccaag
     3241 accaagagat tgggcttttc aaggagcatt ttagctagag ccaaacgagt attttgacca
     3301 cctgaaagtt cagctatttt catctgccac atagactcgt caaacttgaa tccattcaaa
     3361 atcgctcgaa tatcagcttc ataggtaaag ccacctgctt ggcgaaaatt ctcagataag
     3421 cggtcataat ctgacatcag tttatccaaa tcctcaccag acttttcacc catctccagc
     3481 tccatctgac gcagttgtct ctccgtccga cgcaaatcat taaagacatg aagcatttca
     3541 tcgtagatgg tattttcaga ctcaaaacgg ctatcttggg ctaggtaaga cagagaaata
     3601 tcttttttct tattgatttc tccgctagtt ggctcctctt ctccaactaa aatcttcaaa
     3661 agagtagact tacctgcacc atttttccca acaagagcaa tccgatctcg ttcatcaacc
     3721 tgcaggttga tattatcgaa aagaacctct cctgcaaaag aacgttcaat tttattagct
     3781 tgtaaaataa tcataagagt agtatagcat gtttccctaa ggcattcaag ataatcgtaa
     3841 gtcttttagt acaactttta taacataaaa taaactaaat tatgtatatt ttatattaga
     3901 ttccttcact atcttgttgg attttctaac cagctaatct tgtttcaaat agttatcgca
     3961 caagcctatt atttaattct tttcattatt tacgtacgcg tatagcagat tgaaataaga
     4021 tgagaacaaa tcgattggga aagtaaaatt aatttctata aatgttttag caattgtttc
     4081 gtactatttt agattcagtc tactatgtac aatattttcg gaacattcaa ctttttaact
     4141 ctatttatta ctagatttca taattaaaaa gcctactgac caagctagaa agcttgatac
     4201 aataggcttt ttaaagactg attatttaac agcgtcttta agagctttac cagctttgaa
     4261 tgctggtact ttagaagctg caattgtcat ttctttacca gtttgtgggt tgcgaccttt
     4321 acgttctgca cgctcacgaa cttcaaagtt accaaaaccg atcaattgaa ctttttcacc
     4381 agctgcaaga tagtcagcta ctgctgcaaa tacagcttca actgctgctg ctgagtcttt
     4441 cttagtcaat tctgtagctt ctgctacttt agcgatcaaa tcttgtttgt ttgccatgtt
     4501 aatgattcct ccagataatt tctaattaac aaatataatc atatcctaaa atccctttta
     4561 ggtcaagtta aaaacgctat ttcttccaat tttatttatt ttttaggagt ggtaacgtat
     4621 caaaatagcc caagcgttct cacccgtgtg agtttgaata atggaacccg tttccaaaac
     4681 agaaattggc ttttcaacat aagcttgtaa gctttctttc atctcttttg cccaatcatc
     4741 actaccagaa tatgaaattc caatctctgc tacagcacgt tcagaaagcg atgttatcaa
     4801 ctcatctaac cattttttaa atgttttagt tccacgacct ttaaccattg gctgcaattc
     4861 atggtctttc atttgcatga caacacggat attgagaagg gagctcaaca agccagttac
     4921 acggccaatt cgtccacctt tgacaagatt ttccaaagtt gaaacaccaa tataaagctc
     4981 tgtatggttt ttaacctctt ctacatgaga taaaattgcc tccatatctt taccttcttg
     5041 agctaacttc gcagcctcaa caacttggaa tttcagggct tggtcagtga aggaactatc
     5101 aacaacaatc acatctgcag tagataggct agcaccttgg cgtgctgctt ctaccgtacc
     5161 cgaaagagca tgggacatat gaatagcaag aatctggcca ccatctttgc ataggtcttc
     5221 aaaaatctca gcaaagacac ctacaggtgg ctgacttgtt ttcggaagat tcttactttc
     5281 ttgcatcaac tgaagaaatt taccttcttc tttcaaatcc gcatcagaat aaacaacatt
     5341 atcaatcatt acagataatg gaacaattgt aatatctaat tgctttacta gttcaggttc
     5401 aatagtaaca gatgaatcgg ttacaatctt aatttttgtc atagtatcaa tctttctatt
     5461 ttaggattca gattggtttc cttacttcta attatatcaa aaaaaagatt aaaaatccta
     5521 atggagtcaa tcaaattttc cgtaaaattt gatataatca acttataaga aaagaggtgt
     5581 cctatgatta aaaaaattta ccccattttt accattttac taggtgctgc tatttatgct
     5641 tttggactga cttattttgt agttccccat catctctttg aaggaggggc gacaggtatt
     5701 accctcatca cattttatct ttttaaaatc cctgtttccc tcatgaacct gctgattaat
     5761 attccccttt tcatcctagc ttggaagatc tttggagcca aatccctcta ttctagttta
     5821 ctaggaacct tagctttgtc cggctggtta gctttttttg agcatattcc ccttcatatt
     5881 gatcttcaag gtgatttact aataacagcc cttatagcgg gaatcctatt gggaattggc
     5941 cttggaatta tttttaatgc tggaggtaca actggcggaa ctgatattct agctcgtatt
     6001 ctcaacaaat acactcatat atccatagga aaactgctct ttatcttaga tttttgtatt
     6061 ctcatgttga ttctcctaat cttcaaggat ttgagattgg tttcctacac gcttttgttt
     6121 gattttattg tttctcgtgt tattgatttg attggtgaag gaggatatgc cggcaaaggc
     6181 tttatgatta tcacaaaacg tcctgaccaa cttgctaagg cgattaatga tgacctcgga
     6241 agaggtgtta cttttatttc tggtcaaggc tactatagta aagaaaattt gaaaatcatc
     6301 tactgtattg tcggaagaaa tgaaattgtg aaaacgaagg aaatgattca tcgaatcgat
     6361 cctcaagcct ttataactat tacagaagcc catgaaatcc taggagaagg cttcaccttt
     6421 gaaaaagaat aaaaagaggt aatgtcgtga cctcaaaagt tagactaaat catctatctt
     6481 ttgggttaca gacaacctct tttttgtttt atttactcaa gctcttaaga ccaattccga
     6541 gttacttctt catcagcctt taactgatcc actaattggt caactgagtc aaatttggtc
     6601 atatcacgaa tgcgatcaag ccaataaacc atgacggttt ccccataaat atcttgatta
     6661 aaatcaaaaa tattgacttc aaaacgtgct tcttctccat caaaggtcac atttttcccg
     6721 acactagcca tagcacgata cttctgtctt tgaatctcaa catcaacgac ataaacgcca
     6781 tctgctggca tataagtacg gtctaaaagc actaaattcg ctgtcggata accaattgta
     6841 cgaccacgag cattaccatg aaccaccata cctcttgatg gaagcggtgc ccccaaaagt
     6901 tttcctgctt ctttcacatt tccatctaaa atagcttgac ggatacgagt tgaactaatc
     6961 tttcctttct catcttctac aggtggaaca atgataactt ctccatcaaa gtaatccttt
     7021 aaatcttctg ctgttttttt gtcagaacca aatgtataat caaaacctgc aacaataatt
     7081 ttggcattca tagccttgat ataagttgca aagaattctt gtgcagtgag actagcgaat
     7141 tgactactaa aatcaaggag atataattct tctacacctt cgcgctttaa ttttctttca
     7201 cgttcagcag ggttcaaaat atgcaaaaac aaatccggat gataaggctc taaagcgatc
     7261 tttggagatt cattaaaggt cataacgacg ataggtaata aatcctttct cgcagccttg
     7321 ttggcaacac gaaataattc ttgatgcccc ttatgtatgc catcaaaata gccgagaaca
     7381 acgactgaat cagatggtgt gccaatatct ttttggtttt ttataggaat agtaataatc
     7441 ataaaataat tatatcatag cgatagctat ttctggaaca gaaaatctga aatgttgttt
     7501 ttttcacatg aagtgtacct gttttcaaaa agcactttat tctatcgttg cttaactatg
     7561 aactttgcaa tattcttctc aaaaacttgt aggacatctt caaaattttg caaggagtga
     7621 ttagacttgt tcggtaacca taaagtgtca tactatgtta tgtatgaaaa agcaatgcaa
     7681 ctaactcctg agaactttaa attactaatt ggtgccgaaa aggtagaatt tagaatcgag
     7741 gtacacctat ggctgtaaaa tttacaaaat gagacaactt gggcaagatg tttgaagaat
     7801 ttcctaaact ccctgatttg aagcaagtca ctttccctga tgacaaagaa aaaagccaaa
     7861 acagcaaaga aaaactagat gactgctttc caacaactcc catctagtgt gcttcagact
     7921 gggctatttt tctctccatc tgttagcttg gattctcaga ccgtttcagc taaagaatat
     7981 cttttccctt atcagaagga acggctcaaa ccattcagac aagtgaaggg acgacaagcc
     8041 aatatttgaa accagatagc agttcttata gtcaattgaa ataaaatctg aagaaatcga
     8101 gtaggaaact catatcaatt tttaacagtg ttctattcca gattcatact caatgaaaat
     8161 taaagtgcaa actaggaagt tagccgcagg ctgtacttga gtacggcaag gtgaaactga
     8221 cgtggtttga atttgatttt cgaagagtat caatccacta tacatattaa aaagtatgga
     8281 tatcaaaaca aaaaaacagg ctctccgaaa actcggaaag ccttatttta agctgtttct
     8341 agcttcctca cctttacatt tcaaggttcg ggataaaagg ttcaatggac ctttttattt
     8401 agcgattggg taaacagaaa cttgtttttt atcgcgtcct ttacgttcaa agcgtactac
     8461 gccttcaact ttagcgaaca aagtatcgtc tccaccacga ccaacgttta cacctggata
     8521 gatgtgtgta ccacgttgac ggtaaaggat tgatccacct gttacagttt gtccgtcagc
     8581 tgctttagct ccaagacgtt ttgcttgtga atcacgtccg tttgatgtag aacctccacc
     8641 ttttttgtgg gcgaaaagtt gcaagttgtt aagagtcatt tttaacataa tgttttcctc
     8701 cgtgttagtt ttctgtgata actctggttt ggacgaactc agaatagttc tccgataagt
     8761 ttgccatacc taagaaaaat gattcaaaga ataactgggt catttctctc tggtgtgaag
     8821 gaagatcttt tggtatttca accatcagat agccaccttc atcttcgttt aattctagga
     8881 ttggttcata gcctgcaaat ttctcaatag aattgataaa gttaatggca agcgtagaaa
     8941 ccgatgcaca cacgacatct aagccgtatt cgccactctc ggcgtgtcca gtaatttccg
     9001 cacccctcag ctcgccatct tcggctctct caaagactgc ttgtatcatg tgttctcctt
     9061 aaaattaagc gttaattgcg ttgatgacaa cttttgtata tggttgacgg tgaccttgtt
     9121 tacggtggct acctttttta ggtttgtact tgtaagtaac aactttcttt tgttttcctt
     9181 gtttttcaac agttccaact acagtagctc cagcaacaag tggagttccg acaacagtgt
     9241 tttcaccacc aacaagaaca acttcgttaa aagtaacttc ttgaccagct tcaacgttca
     9301 atttttcaat gtaaactgct tgaccaactt caactttaac ttgttttccg ccagttttga
     9361 taattgcgta tgtgctcatt atgcacctcc tatgattttt atgggtttcc ccgatttttt
     9421 gtgaagactc gcctagcatc gtgggacaaa ccacttaaac ttgaataatc aagcaacgat
     9481 gttcgtgcgg ttgcacagga tcgtgcatag tcaactcttc aagtatagca tatctcctat
     9541 tttcttacaa gtaataacac ctaaaatcaa gctttttctt ttactttttt ctgccactag
     9601 gcaaaaagca tactgagata aaaaatgctc atcataatag gaacaccaag aatggtcttt
     9661 tcatgataga aaatcgtcaa ataggctgaa aagacatcgc caaggacaaa actactaagc
     9721 aggctaacaa atatgaaccc ttcacgcaaa aaaggagtgt gcttagttcg gaaataatct
     9781 ccaaaagcta gcattgttcg tttgatattc cctgtcataa aggcattatt gtaggcaata
     9841 cccgaaacct caccaaaagc agttgtcacc agtcccatac agaaggccaa gggctgcact
     9901 agatagatat tatctacagt ttgtggcaca aaaccaataa ttattgatag gattgctaaa
     9961 ggaatcaagg acagaatagg ttttttcaca attctcaatt tttccttata aatcgttaat
    10021 aaaaagactc ccattataaa cgttattaag gttaaaagct tatccctaac atccgaaaca
    10081 ttattttgta ttagctctac cgaaagaaag acaacatttc cagcttgtcc agctacaagg
    10141 gtattccctc gaacaataaa agtgtaagca tccacatatc cagcacaaaa tgtcaaaaaa
    10201 gtgctaacct tttagactga cgtgatattt ttcttatagg taataacctc attttccctc
    10261 ccattgtatt ttctcttaga aatattgtac catttctttc taaaaaatcg tagactacca
    10321 tttagatttt actattagca taaaaataat aatagacaac tatttatcca aaaatagata
    10381 gaggtaacat gtttgcaaac aaagcatacg aacctttagt aaaatcattt ccatgaaact
    10441 agaatagagc ccctcttagc aaaaatcatt attttaattt atttctaatc actccttgac
    10501 ataaataact ctcaccaata aaagactatg tcttaaaaaa atggtataat aaaatcaata
    10561 cctgggcttg atggctatgc tactaataac aattaggaga gaaaatcagg cacttgttaa
    10621 caacaaggat tatccccttg agatgaaagg aactttagaa atcttatgat gaacatgcaa
    10681 aacatgatgc gtcaagcaca aaaacttcaa aaacaaatgg aacaaagcca agctgaactt
    10741 gctgctatgc aatttgttgg caaatctgct caagatcttg tccaagcgac cttaactggc
    10801 gataagaaag ttgtcagcat tgatttcaat ccagctgtcg ttgacccaga ggaccttgag
    10861 actctttctg atatgaccgt tcaagccatc aactctgctc ttgaacaaat cgatgaaact
    10921 actaagaaaa aactgggtgc tttcgctggg aaattgccat tctaaaaaca aggagctaga
    10981 acaatacttg tcgataacaa aggctaagaa aggtgcaaaa attataaaaa acgcatagta
    11041 tcaagcaacc taaaactttg ggctctataa tatttgtagt gggtaaatcc actatagata
    11101 ttatggagcc tattttattg tagaaaaaaa tcccataaga tctataatga aaagcgacca
    11161 aacaactcat tagaaagatt catatgggac aattacattt tatcacaaaa ttactagaca
    11221 ttaaagaccc taatatccag attttagaca tcatcaataa ggatacacac aaggaaatca
    11281 tcgccaaact ggactacgac gccccatctt gccctgagtg cggaagtcaa atgaagaaat
    11341 atgactttca aaaaccgtct aagattcctt accttgagac aactggtatg cctactagaa
    11401 t
//
LOCUS       DAVBEO010000062        10989 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 009
            SAMEA1678075-rid20185393.denovo.062, whole genome shotgun sequence.
ACCESSION   DAVBEO010000062 DAVBEO010000000
VERSION     DAVBEO010000062.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678075
            Sequence Read Archive: ERR226392
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10989)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10989)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980207.1
            Genome Coverage       :: 150x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:50:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 72 of 147
            Pseudo Genes (incomplete)         :: 72 of 147
            Pseudo Genes (internal stop)      :: 42 of 147
            Pseudo Genes (multiple problems)  :: 32 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10989
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678075-rid20185393.denovo.062"
                     /strain="KS 009"
                     /db_xref="taxon:1313"
     gene            136..2316
                     /locus_tag="VQ543_001871"
     CDS             136..2316
                     /locus_tag="VQ543_001871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000974069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HET2612540.1"
                     /translation="MMKDTFKNVLSFEFWQKFGKALMVVIAVMPAAGLMISIGKSIVM
                     INPTFTPLVITGGILEQIGWGVIGNLHILFALAIGGSWAKERAGGAFAAGLAFILINR
                     ITGTIFGVSGDMLKNPDAMVTTFFGGSIKVADYFISVLEAPALNMGVFVGIISGFVGA
                     TAYNKYYNFRKLPDALSFFNGKRFVPFVVILRSAIAAILLAAFWPVVQTGINNFGIWI
                     ANSQETAPILAPFLYGTLERLLLPFGLHHMLTIPMNYTALGGTYDILTGAAKGTQVFG
                     QDPLWLAWVTDLVNLKGTDTSQYQHLLDTVHPARFKVGQMIGSFGILMGVIVAIYRNV
                     DADKKHKYKGMMIATALATFLTGVTEPIEYMFMFIATPMYLVYSLVQGAAFAMADVVN
                     LRMHSFGSIEFLTRTPIAISAGIGMDIVNFVWVTVLFAVIMYFIANFMIQKFNYATPG
                     RNGNYETAEGSEETSSEVKVAAGSQAVNIINLLGGRVNIVDVDACMTRLRVTVKDADK
                     VGNAEQWKAEGAMGLVMKGQGVQAIYGPKADILKSDIQDILDSGEIIPETLPSQMTEA
                     QQNTVHFKNLTEEVYSVADGQVVGLEQVKDPVFAQKMMGDGFAVEPANGNIVSPVSGT
                     VSSIFPTKHAFGIVTEAGLEVLVHIGLDTVSLEGKPFTVHVAEGQKVAAGDLLVTADL
                     DAIRAAGRETSTVVVFTNGDAIKSVKLEKTGSLAAKTAVAKVEL"
     gene            2368..3183
                     /locus_tag="VQ543_001872"
     CDS             2368..3183
                     /locus_tag="VQ543_001872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HET2612541.1"
                     /translation="MKFLTLNTHSWMEKEAEEKFQILLEDILEKDYDLICFQEINQEM
                     TSSEVEVNDLYQALPAAEPIHQDHYVRLLVEKLLEQGKNYYWTWAYNHIGYDRYHEGV
                     AILSKTPIEAREILVSDVDDPTDYHTRRVALAETLVDGKELAVASVHLSWWDKGFQEE
                     WARFEAVLKKLNKPLLLAGDFNNPAGQEGYQAILASPLGLQDAFEVAQEKSGSYTVPP
                     EIDGWKGNTEPLRIDYVFTTKELAVENLHVVFDGNKSPQVSDHYGLNAMLNWK"
     gene            3323..4666
                     /locus_tag="VQ543_001873"
     CDS             3323..4666
                     /locus_tag="VQ543_001873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HET2612542.1"
                     /translation="MSFTKFQFKNYIREALKELKFTTPTEVQDKLIPIVLAGRDLVGE
                     SKTGSGKTHTFLLPIFQQLDEASDSVQAVITAPSRELATQIYQVARQISAHSDVEVRV
                     VNYVGGTDKARQIEKLASNQPHIVIGTPGRIYDLVKSGDLAIHKAKTFVVDEADMTLD
                     MGFLEIVDKIAGSLPKDLQFMVFSATIPQKLQPFLKKYLSNPVMEKIKTKTVISDTID
                     NWLISTKGHDKNAQIYQLTQLMQPYLAMIFVNTKTRADELHSYLTAQGLKVAKIHGDI
                     APRERKRIMNQVQNLDFEYIVATDLAARGIDIEGVSHVINDAIPQDLSFFVHRVGRTG
                     RNGLPGTAITLYQPSDDSDIRELEKLGIKFSPKMVKDGEFQDTYDRDRRANREKKQDK
                     LDIEMIGLVKKKKKKVKPGYKKKIQWAVDEKRRKTKRAENRARGRAERKAKRQTF"
     gene            5043..6233
                     /locus_tag="VQ543_001874"
     CDS             5043..6233
                     /locus_tag="VQ543_001874"
                     /EC_number="2.5.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000003937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine adenosyltransferase"
                     /protein_id="HET2612543.1"
                     /translation="MSERKLFTSESVSEGHPDKIADQISDAILDAILAKDPEAHVAAE
                     TAVYTGSVHVFGEISTNAYVDINRVVRDTIAEIGYTNTEYGFSAETVGVHPSLVEQSP
                     DIAQGVNEALEVRGNADQDPLDLIGAGDQGLMFGFAVDETEELMPLPIALSHKLVRRL
                     AELRKSGEISYLRPDAKSQVTVEYDENDRPVRVDTVVISTQHDPEATNEQIHQDVIDK
                     VIKEVIPSSYLDDKTKFFINPTGRFVIGGPQGDSGLTGRKIIVDTYGGYSRHGGGAFS
                     GKDATKVDRSASYAARYIAKNIVAAGLAKKAEVQLAYAIGVAQPVSVRIDTFGTGTVA
                     ESQLEKAARQIFDLRPAGIIQMLDLKRPIYRQTSAYGHMGRTDIDLPWERLDKVDALK
                     EAVK"
     gene            6786..7721
                     /locus_tag="VQ543_001875"
     CDS             6786..7721
                     /locus_tag="VQ543_001875"
                     /EC_number="1.3.98.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate oxidase"
                     /protein_id="HET2612544.1"
                     /translation="MVSTKTQIAGFEFDNCLMNAAGVACMTIEELEEVKNSAAGTFVT
                     KTATLDFRQGNPEPRYQDVPLGSINSMGLPNNGLDYYLDYLLDLQEKESNRTFFLSLV
                     GMSPEETHTILKKVQESDFRGLTELNLSCPNVPGKPQIAYDFETTDRILAEVFAYFTK
                     PLGIKLPPYFDIVHFDQAAAIFNKYPLKFVNCVNSIGNGLYIEDESVVIRPKNGFGGI
                     GGEYIKPTALANVHAFYQRLNPQIQIIGTGGVLTGRDAFEHILCGASMVQVGTTLHKE
                     GVSAFDRITNELKAIMVEKGYESLEDFRGKLRYID"
     gene            7755..8792
                     /locus_tag="VQ543_001876"
     CDS             7755..8792
                     /locus_tag="VQ543_001876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001845438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HET2612545.1"
                     /translation="MLAIEESQKLTLSNLPSLSLFTGTDQGQFEVMKSQVLKQIGYDS
                     ADLNFAYFDMKEVVYKDVELELVSLPFFADEKIVILDYFMDITTAKKRFLTDDELKSF
                     EEYLDNSSPTTKLIIFAEGKLDSKRRLVKLLKRDAKVFDAVEVKEQELRQYFQKWSQK
                     QGLQFTNHSFENLLIKSGFQFSEIQKNLLFLQSYKANSVIEEEDIVNAIPKTLQDNIF
                     DLTQFILTKKMDQARDLVRDLTLQGEDEIKLIAVMLGQFRTFTQVKILAESGQTESQI
                     ASSLGSYLGRNPNPYQIKFALRDSRGLSLSFLKQAISYLIETDYQIKTGLYEKGFLFE
                     KALLQIASQVN"
     gene            8965..9570
                     /locus_tag="VQ543_001877"
     CDS             8965..9570
                     /locus_tag="VQ543_001877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase"
                     /protein_id="HET2612546.1"
                     /translation="MAIILPELPYAYDALEPYIDAETMHLHHDKHHQTYVNNANAALE
                     KHPEIGEDLEALLADVESIPADIRQALINNGGGHLNHALFWELMTPEKTAPSAELAAA
                     IDATFGSFEEFQAAFTAAATTRFGSGWAWLVVNKEGKLEVTSTANQDTPISEGKKPIL
                     GLDVWEHAYYVKYRNVRPDYIKAFFSVINWNKVDELYAAAK"
     gene            9726..10256
                     /locus_tag="VQ543_001878"
     CDS             9726..10256
                     /locus_tag="VQ543_001878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YutD family protein"
                     /protein_id="HET2612547.1"
                     /translation="MRKEIAPELYNYNKFPGPEFHLHGDKVETEGIAFSLVENIKDAF
                     DVTTFNQRFSEVLTKFDYIVGDWSNEQLRLRGFYKDDRTEEKLEKISRLQDYLLEYCS
                     YGCAYFVLENEAPKRASFDKKMRKTEEETPSRKGKKPTQTKRKSNADKKNRRRQKDQH
                     SQKEDKEQRHFVIRQK"
     gene            10277..>10989
                     /gene="rlmN"
                     /locus_tag="VQ543_001879"
     CDS             10277..>10989
                     /gene="rlmN"
                     /locus_tag="VQ543_001879"
                     /EC_number="2.1.1.192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000804770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HET2612548.1"
                     /translation="MKPSIHSLAHQTMQEWVLEQGEKKFRADQIWEWLYRKRVQSFEE
                     MTNLSKDLIAKLNDQFVVNPLKQGIVQESADGTVKYLFELPDGMLIETVLMCQHYGLS
                     VCVTTQVGCNIGCTFCASGLIKKQRDLNNGEIVAQIMLVQKYFDERGQDERISHIVVM
                     GIGEPFDNYNNVLNFFRTINDDKGMAIGARHITVSISGLAHKIRDFADEGVQVNLAVS
                     LHAPNNELRSSIMKINRAFP"
BASE COUNT         3341 a         2017 c         2395 g         3236 t
ORIGIN      
        1 tagaaatttt ttagaaaaaa gtgtaatttt tttataaaag cctttacaaa aaaaattaaa
       61 gtggtataat taaatcatag aaggtgcaaa cgttttcgta aaacgtttgc ctaaataaaa
      121 ataaaggaga tttgaatgat gaaagataca ttcaaaaatg tcttgtcttt cgaattttgg
      181 caaaaattcg gtaaggcttt gatggtagtt atcgcggtta tgccggctgc tggtttgatg
      241 atttcaatcg gtaagtctat cgtgatgatt aacccaacct ttacaccact tgtcatcaca
      301 ggtggaattc ttgagcaaat cggttggggg gttatcggta accttcacat tttgtttgcc
      361 ctagccattg gaggaagctg ggctaaagaa cgtgctggtg gtgctttcgc cgctggtctt
      421 gccttcatct tgattaaccg tatcactggt acaatttttg gtgtatcagg cgatatgttg
      481 aaaaatccag atgctatggt aactactttc tttggtggtt caatcaaagt tgctgattac
      541 tttatcagtg ttcttgaagc tccagccttg aacatggggg tattcgtagg gattatctca
      601 ggttttgtag gggcaactgc ttacaacaaa tactacaact tccgtaaact tcctgatgca
      661 ctttcattct tcaacgggaa acgtttcgta ccatttgtag ttattcttcg ttcagcaatc
      721 gctgcaattc tacttgctgc tttctggcca gtagttcaaa caggtatcaa taacttcggt
      781 atctggattg ccaactcaca agaaactgct ccaattcttg caccattctt gtatggtact
      841 ttggaacgtt tgctcttgcc atttggtctt caccacatgt tgactatccc aatgaactac
      901 acagctcttg gtggtactta tgacatttta actggtgcag ctaaaggtac tcaagtattc
      961 ggtcaagacc cactatggct tgcatgggta acagaccttg taaaccttaa aggtactgat
     1021 actagtcaat atcaacactt gttagataca gtacatccag ctcgtttcaa agttggacaa
     1081 atgatcggtt cattcggtat cttgatgggt gtgattgttg ctatctaccg taatgttgat
     1141 gctgacaaga aacataaata caaaggtatg atgattgcaa cagctcttgc aacattcttg
     1201 acaggggtta ctgaaccaat cgaatacatg ttcatgttca tcgcaacacc tatgtatctt
     1261 gtttactcac ttgttcaagg tgctgccttc gctatggctg acgtcgtaaa cctacgtatg
     1321 cactcattcg gttcaatcga gttcttgact cgtacaccta ttgcaatcag tgctggtatt
     1381 ggtatggata tcgttaactt cgtttgggta actgttctct ttgctgtaat catgtacttt
     1441 atcgcaaact tcatgattca aaaattcaac tacgcaactc cagggcgcaa cggaaactac
     1501 gaaactgctg aaggttcaga agaaaccagc agcgaagtga aagttgcagc aggctctcaa
     1561 gctgtaaaca ttatcaacct tcttggtgga cgtgtaaaca tcgttgatgt tgatgcatgt
     1621 atgactcgtc ttcgtgtaac tgttaaagat gcagataaag taggaaatgc agagcaatgg
     1681 aaagcagaag gagctatggg tcttgtgatg aaaggacaag gggttcaagc tatctacggt
     1741 ccaaaagctg acattttgaa atctgatatc caagatatcc ttgattcagg tgaaatcatt
     1801 cctgaaactc ttccaagcca aatgactgaa gcacaacaaa acactgttca cttcaaaaat
     1861 cttactgagg aagtttactc agtagcagac ggtcaagttg ttggtttgga acaagtaaag
     1921 gatccagtat ttgctcaaaa aatgatgggt gatggatttg cagtagaacc tgcaaatgga
     1981 aacattgtat ctccagtttc aggtactgtg tcaagcatct tcccaacaaa acatgctttt
     2041 ggtattgtga cggaagcagg tcttgaagta ttggttcaca ttggtttgga cacagtaagt
     2101 cttgaaggta aaccatttac agttcatgtt gctgaaggac aaaaagttgc agcaggagat
     2161 ctccttgtca cagctgactt ggatgctatc cgtgcagcag gacgtgaaac ttcaacagta
     2221 gttgtcttca caaatggtga tgcaattaaa tcagttaaat tagaaaaaac aggttctctt
     2281 gcagctaaaa cagcagttgc taaagtagaa ttgtaatata cttgaggttg gaagctgtat
     2341 tccaacctct tattttggga gaaaagaatg aaatttttaa cactcaatac tcacagttgg
     2401 atggagaaag aagcagagga aaaattccag attttgcttg aagatattct tgaaaaggac
     2461 tatgatttga tttgtttcca agaaatcaat caggagatga cctcgtcaga ggtggaggtt
     2521 aatgaccttt atcaagcttt gccagcagct gagcctattc accaagacca ttatgttaga
     2581 ctcttggttg aaaagttgtt agagcaaggg aaaaattact actggacctg ggcttataac
     2641 catatcggct atgaccgcta ccacgaaggt gtggctatct tgtctaaaac acctattgaa
     2701 gccagagaaa ttttggtttc agatgtggat gatccaacag actatcatac tcgccgtgtt
     2761 gccctagctg aaactttagt cgatggcaag gagctagcag ttgccagtgt tcatctctct
     2821 tggtgggata aaggtttcca agaagaatgg gcacgatttg aggctgtctt gaaaaaattg
     2881 aacaagccac ttttactagc tggagatttt aacaacccag caggtcagga aggttaccaa
     2941 gctattttag ctagtccatt aggcttacaa gacgcatttg aagttgctca agagaaaagt
     3001 ggtagctata ctgttccgcc tgaaattgat ggctggaaag ggaacactga accccttcga
     3061 atcgattatg tctttactac caaagagtta gcggtggaaa atttacatgt cgtatttgat
     3121 ggtaacaaga gtccacaagt gagtgatcac tatggcttga atgctatgtt aaactggaaa
     3181 taataactga aaagaggttg gaactataaa attccagcct tttcttacta gagaagctac
     3241 tggaaatagc ctaaataagt gagactactg taatggaata aaatatggta taattgataa
     3301 gatagataga atcgaggatg ttatgtcatt tacgaaattt caatttaaaa actatattag
     3361 agaagccttg aaggagttaa aatttacaac tccaacagag gtgcaagata agttgattcc
     3421 tattgttttg gcaggtcgtg acctagtagg agaatcaaaa acaggttcag gtaagactca
     3481 tactttcttg ttaccgattt tccagcaatt agatgaagct agcgatagtg tacaagcagt
     3541 gattactgca ccgagtcgtg agttggctac tcaaatttac caagtagcgc gtcagatttc
     3601 agctcactca gatgtcgaag ttcgtgtggt taattatgtg ggtggtacgg ataaggctcg
     3661 ccagattgag aaattggcaa gcaatcagcc tcatattgtt attggaacac caggccgtat
     3721 ctacgacttg gttaaatctg gtgatttagc tattcataaa gccaagacat ttgttgttga
     3781 tgaagcagat atgaccttgg atatgggatt cttggaaatt gttgataaga ttgctggcag
     3841 tcttccaaaa gacttgcaat tcatggtctt ctcagcgact atcccacaaa aactgcaacc
     3901 attcttgaaa aaatacttat caaatcctgt tatggagaaa attaagacta aaacggttat
     3961 ttctgacacc attgataatt ggttgatttc gaccaaggga catgataaga atgctcaaat
     4021 ttaccaattg actcagttga tgcagccgta tttggcaatg atttttgtta acactaaaac
     4081 gcgtgctgat gaattgcatt catatctgac tgctcaaggc ttgaaggttg caaaaatcca
     4141 tggagatatt gcccctcgtg aacgcaagcg aatcatgaat caggtgcaaa atctggattt
     4201 tgagtatatt gtcgcaacag atttagcagc gcgtgggatt gacattgaag gtgtcagcca
     4261 tgtcatcaat gatgccattc cgcaagactt atcttttttt gttcaccgtg ttggtcgtac
     4321 tggacgaaat ggcctaccag gtacagctat taccctttat cagccaagtg atgactcgga
     4381 tatccgtgag ttggagaaat tgggaatcaa gtttagtcct aagatggtca aagatgggga
     4441 atttcaagat acctatgacc gtgatcgtcg tgccaaccgt gagaaaaaac aagataaact
     4501 tgatatcgaa atgattggtt tggttaaaaa gaaaaagaaa aaagtcaaac cgggttataa
     4561 gaagaaaatt caatgggcgg ttgatgaaaa gcgccgtaaa actaagcgtg ctgaaaatcg
     4621 cgctcgcggt cgtgcagagc gtaaagctaa acgccaaaca ttttaataga aattgttgga
     4681 gtactgagct ccaacttttt tatttatgag aacgaactat ctaaaccgaa acactacatt
     4741 aaagactgca aattgcgatt aaaaatggta taatgataaa gttatatagt cccgataaga
     4801 tggtaggtat ttattacgaa gagttttcct atcagtagtt tgcaattcgc aaagaatgac
     4861 ggcttcgagg tcgctcgtct ttctacggtt gccgccatac tgcggtcacc ctatgcgcct
     4921 tactagcttc agaaataaaa aagtatcgtt tttatttctg aagctagtaa ctcttagata
     4981 atggaaattc ctatcagtac tttgtaactc tataacaata ttttttaagg ggggacattt
     5041 ttatgtcaga acgtaaatta ttcacgtctg aatctgtatc tgaggggcat ccggataaga
     5101 ttgcagacca aatttcagat gcgattttgg atgctatttt agcaaaggat ccagaggcgc
     5161 acgttgctgc tgaaacagct gtatatactg gttctgtcca cgtttttggt gaaatttcta
     5221 caaatgccta tgtggatatt aaccgtgtgg ttcgtgatac cattgcagag attggttata
     5281 ccaatacaga atatggattt tctgctgaga cggtgggagt acacccatct ttggtggaac
     5341 aatctcctga catcgctcaa ggtgttaacg aagccttgga ggttcgtgga aatgctgatc
     5401 aagatccact ggacttgatt ggagcaggtg accaagggct catgtttgga tttgcagtag
     5461 atgaaacaga agagctcatg ccattgccaa ttgcactcag tcataaattg gttcgtcgtc
     5521 tggcagaact tcgtaagtct ggagaaatta gctatctccg tccagatgca aaatcacaag
     5581 ttacagttga gtacgatgaa aatgaccgtc cggtacgtgt agatacagtc gttatttcta
     5641 ctcagcatga tccagaggcc actaatgaac aaatccatca agatgtgatt gacaaggtca
     5701 tcaaagaagt tattccatct tcttatcttg atgataagac aaaattcttt atcaatccga
     5761 caggtcgttt tgtaatcggt ggtcctcaag gggactcagg tttgactggt cgtaagatta
     5821 ttgtagatac ttatggtggc tactctcgtc atggtggtgg tgccttctct ggtaaagatg
     5881 cgactaaggt ggatcgttca gcctcttatg cggctcgcta tattgccaag aatatcgttg
     5941 cagcaggcct tgctaagaag gcagaagtgc agttggccta tgctatcggt gttgcgcaac
     6001 ctgtttctgt tcgtatcgat actttcggta caggaacagt agctgaaagt caacttgaaa
     6061 aagcggctcg tcaaatcttt gaccttcgcc ctgcagggat tatccaaatg ctggacctca
     6121 agcgtccaat ttaccgtcaa acatcggctt acggtcacat gggacgtaca gatattgatc
     6181 ttccatggga acgtttggat aaggtagatg ctttgaaaga agcagtaaaa taagatttta
     6241 agaggggaac gtcctctctt ttttatagtt tttaactata ctgggatact gttctgaaaa
     6301 tccattttgc gaaagtagag atttacatgt ataatggatt gaaactagaa tagtacacct
     6361 caacttctaa aacattgtta gaaatcgatt tgactgtcct gatcgatttc tcctgttctt
     6421 gtttcatttt actatatttc tttaaaaatg ataaaggttg agatttctcc tcgtaataga
     6481 taatcatggg gatatttcaa tccaaagttt tattcgttat cacttgacta ttgcaaggtt
     6541 ttctagagca acagagtcat ggaatggact catggttgag atttctcctt gttgcttgga
     6601 cttcattcaa aagtctgtta cccaagcctt gttcaaactt ccaatacact agctgtttcc
     6661 atagcatgac ttctgtacta gactttcttt tccgaataaa tagatagaac cacagaatct
     6721 agtaaaccta gaattaaaat tatggtataa tattagcaat aaaagaaatc tggaggatta
     6781 gaatcatggt atcaacgaaa acacaaattg ctggttttga gtttgacaat tgcttgatga
     6841 atgcagcagg tgtggcttgt atgacgatag aggagttaga agaggtcaaa aactcagcgg
     6901 caggaacctt tgttactaag acagcgacct tggacttccg tcaggggaat cctgagccac
     6961 gctaccaaga tgttccactt ggttccatca actctatggg cttgccaaat aatggcttag
     7021 actattattt ggattatctt ttagatttgc aggaaaaaga gtcgaaccga actttcttct
     7081 tatctctggt cggcatgtct ccagaggaaa cccatactat tttgaaaaaa gtccaagaga
     7141 gtgattttcg tggtctgact gagctaaatc tttcctgtcc aaatgttcca ggtaaacctc
     7201 agattgccta tgattttgag acaacagacc ggattttggc agaagtgttt gcttacttca
     7261 ccaaacctct tggaattaaa ttgccacctt attttgatat tgttcacttt gaccaagcgg
     7321 cagctatttt caacaaatat ccgctcaagt ttgtcaactg tgttaactct atcggaaacg
     7381 gcctctatat agaagacgaa tctgtcgtta ttcggcctaa gaatggtttt ggtggaattg
     7441 gtggagaata catcaaaccg actgctctag ccaatgttca cgccttttat caacgtttaa
     7501 atcctcaaat ccaaattatc ggaacaggtg gcgttctgac tggtcgagat gcctttgaac
     7561 acatcctctg tggagcaagt atggtgcagg tgggaacgac ccttcacaaa gaaggcgtca
     7621 gtgcttttga ccgcattacc aatgaactga aagcaatcat ggtggaaaaa ggctacgaga
     7681 gcttagaaga tttccgtggg aaattgcgct atattgacta aattaaatcg aaaaatctga
     7741 agaaaggaga gacgatgcta gccattgaag aaagtcagaa gttgacttta tcaaatttac
     7801 cgagcctgag cctatttaca gggacagatc agggtcagtt tgaagtgatg aagagtcaag
     7861 tgttgaaaca gattgggtat gattctgctg acctcaactt tgcctacttt gatatgaaag
     7921 aagtagttta caaggatgtg gaactggagt tggtcagcct tcctttcttt gcggatgaga
     7981 aaatcgtgat attagattat tttatggata tcacgactgc taagaaacgc tttttgacag
     8041 atgatgagct taagtcattt gaggaatacc ttgacaattc ttctccaaca accaagttga
     8101 taatctttgc agaaggaaag ctggatagca aaagacggtt agtcaaatta cttaagcgtg
     8161 atgccaaggt cttcgatgca gtagaagtaa aagaacaaga attgcgccag tatttccaaa
     8221 agtggagtca gaaacaaggt ctgcagttta ccaatcattc ttttgaaaat ctcctcatca
     8281 agtcggggtt tcaatttagc gaaatccaga aaaatcttct ctttttacag tcctataagg
     8341 cgaattctgt tattgaggaa gaggatattg ttaacgcaat tcccaagacc ttgcaggaca
     8401 atatttttga tttaactcag tttattctga ctaaaaagat ggatcaggcg cgcgatttgg
     8461 tgagagactt gaccttgcaa ggggaagatg aaatcaaact gattgcagtc atgctgggac
     8521 aatttcggac ttttactcag gtgaagattt tggcggagtc tggccaaaca gaatcgcaga
     8581 ttgcaagtag tttaggtagt tatctgggac gtaacccaaa tccttatcaa atcaagtttg
     8641 cattaagaga ttcgagagga ctttctttga gctttctgaa gcaagctatt tcctatttga
     8701 ttgagacaga ctatcagatt aagacaggtc tttatgaaaa aggtttcctt tttgaaaagg
     8761 cactcttaca gattgctagt caggtcaatt gacatttgtt gaaactacaa cccgcgtcag
     8821 gattatcttg tcgtgggttt cttgctgatt tgcttatttt attagaaagt atgtcagtga
     8881 tttccttatc tataagcaaa aaacttgaaa aaagtgaatg tttgcgttat cattttcata
     8941 tagaaagaaa aagaggtatt acagatggct attatcttac cagaacttcc atatgcatac
     9001 gacgctttgg aaccatacat cgatgcggaa acaatgcatt tgcaccatga caaacaccat
     9061 caaacttatg tcaacaatgc caatgcagct ttagaaaaac accctgaaat cggtgaagac
     9121 cttgaagcct tgcttgctga tgtagaatct atcccagctg atatccgtca agcacttatc
     9181 aacaatggtg gcggacactt gaaccacgct cttttctggg aattgatgac tcccgagaaa
     9241 acagctcctt cagcagaact ggcagcagca atcgatgcaa catttggttc atttgaagaa
     9301 ttccaagcag ccttcactgc agcagcaaca actcgttttg gttcaggttg ggcatggttg
     9361 gttgtcaaca aagaagggaa acttgaagtg acttcaacag caaaccaaga cacaccaatc
     9421 tcagaaggta aaaaaccaat cttgggcttg gacgtttggg aacatgctta ctacgtgaaa
     9481 taccgcaacg tgcgtcctga ctacatcaaa gctttctttt cagtaatcaa ctggaataaa
     9541 gtagatgaat tgtacgcagc tgctaaataa tgatagttgg agggaagaat tgttcttctc
     9601 tttttaggtt ataagattct ggtctgacaa aatcgtcaga cttttttcat ttttatgaga
     9661 aacgtgctaa ctgctagaaa ttatggtaga ataaagtatt aagtaatcgt ggaaaaagga
     9721 tatctatgcg aaaagaaatt gcacctgaat tatacaacta taacaagttt cctggtccgg
     9781 agttccattt acacggggat aaggtcgaaa cggaagggat agctttttcc ttggttgaaa
     9841 atatcaagga tgcctttgat gtgacgactt ttaatcagcg tttttcagaa gtcttaacca
     9901 agtttgatta tatcgtgggg gactggagca acgaacagct tcgcctacga ggtttttaca
     9961 aggatgaccg aacagaagaa aaacttgaaa aaatcagtcg tttacaagac taccttttag
    10021 agtattgtag ttatggttgt gcctattttg tcttagaaaa tgaagcccct aagcgagcat
    10081 catttgacaa gaaaatgcgt aagacggaag aagaaacacc ttctagaaaa ggaaagaaac
    10141 cgactcaaac taaacgaaag tcgaatgcag ataagaaaaa tagacgtcgt cagaaagacc
    10201 agcattctca gaaagaggac aaggaacaac gtcattttgt cattcgtcag aagtgagtag
    10261 agaataagga gaagaaatga aaccctcaat tcatagtttg gcacatcaaa ccatgcagga
    10321 atgggtattg gagcagggag aaaagaaatt ccgtgcagat caaatctggg aatggctcta
    10381 ccgtaaacgt gtgcagtcat ttgaagaaat gaccaacctt tccaaggatt tgattgctaa
    10441 gctcaatgac cagtttgtgg tcaatccctt gaaacaaggt attgtgcaag agtctgctga
    10501 tggtacagtc aaatatctct ttgaattgcc tgacggtatg ttaattgaga ctgtactcat
    10561 gtgtcaacac tatggtttat ctgtctgtgt gaccactcag gtcggctgta atatcggttg
    10621 taccttctgt gcctctggtt tgattaagaa gcagcgtgac ctcaataacg gtgaaatcgt
    10681 agcgcaaatc atgctggttc agaaatactt tgatgagcgt ggtcaggatg aacgcatcag
    10741 ccatatcgtt gtcatgggaa tcggtgagcc ctttgataat tacaacaatg tcttgaattt
    10801 ctttcgtact atcaatgatg ataaaggaat ggctatcggt gctcgtcaca tcacggtttc
    10861 aatctcaggt ttggctcata aaattcgtga ctttgctgat gaaggggttc aggtcaatct
    10921 tgccgtgtct cttcacgcac ccaacaatga acttcgttca agtatcatga agattaaccg
    10981 tgcctttcc
//
LOCUS       DAVBEO010000063        10818 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 009
            SAMEA1678075-rid20185393.denovo.063, whole genome shotgun sequence.
ACCESSION   DAVBEO010000063 DAVBEO010000000
VERSION     DAVBEO010000063.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678075
            Sequence Read Archive: ERR226392
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10818)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10818)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980207.1
            Genome Coverage       :: 150x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:50:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 72 of 147
            Pseudo Genes (incomplete)         :: 72 of 147
            Pseudo Genes (internal stop)      :: 42 of 147
            Pseudo Genes (multiple problems)  :: 32 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10818
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678075-rid20185393.denovo.063"
                     /strain="KS 009"
                     /db_xref="taxon:1313"
     gene            162..452
                     /locus_tag="VQ543_001880"
     CDS             162..452
                     /locus_tag="VQ543_001880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014632364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2612549.1"
                     /translation="MELKDFTEKEQEMIKKRLTMSNISDKETTEKILALVPQDLIKRI
                     PFFVRKHATTRTIKRISIEYPELYAVAQTSGEIPEKNAKNCVRLSQLSLNKR"
     gene            476..1192
                     /locus_tag="VQ543_001881"
     CDS             476..1192
                     /locus_tag="VQ543_001881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HET2612550.1"
                     /translation="MKKYFIGGLGSNAYHSKDFLQELDSQVYFLNPYEKHLRDETELK
                     SWFKNEIVEEESICLIGHSIGGDLARYFASEFEEVKKLILLDGGYLDLDKILPLDTEL
                     EETKNYIKSQIISDLDVLTSKEKSEAKHWSENMEKAVRQSYHWNVEYNRYELAINYEN
                     IEAILRLRRKIQAFKREVGDTLFISPRYPNEATWREEALKELPDYFDTIFLENFGHEL
                     YTQAPKEIASLMNEWLAYFL"
     gene            complement(1321..2136)
                     /locus_tag="VQ543_001882"
     CDS             complement(1321..2136)
                     /locus_tag="VQ543_001882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000617844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03943 family protein"
                     /protein_id="HET2612551.1"
                     /translation="MIRFLVLAGYFELTIYLHLSGKLNQYINMHYSYLAYISMVLSFI
                     LAIVQLYIWMKQVKTHSHLNSRLAKMTSISLLAIPLVIGLTFPTVSLDSQTVSAKGYH
                     FPLSEGTDLAIQTSEGTTSQYLKPDTSSYFSKSAYEKEMRTAADKYLSQDSIQITNEN
                     YMEVMEAIYDYPDEFEGKTIQFTGFVYNDPSHANSQFLFRFGIIHCIADSGVYGLLTK
                     GNTRQYENNTWITAKGKLVNHYHKELKQNLPTLEIDSFTKVDKPENPYVYRAF"
     gene            complement(2133..3038)
                     /locus_tag="VQ543_001883"
     CDS             complement(2133..3038)
                     /locus_tag="VQ543_001883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HET2612552.1"
                     /translation="MTAFQQLPSSVLQTGAIFLSIIIEALPFVLIGSIVSGLIEVYIT
                     PDKVYHFLPRNRWGRIFFGTFVGMLFPSCECGIVPIINRFLEKKVPSYTAVPFLVTAP
                     VINPIVLFATYSAFGNSFHVALLRALGSILVAVILGIFLGFFWQEPIQKENRLACHEH
                     DFSYLSSAKKVFQVFVQAIDEFFDTGRYLVFGCLFASIIQVYVPTRILTSISATPLFA
                     ILLLMILAFLLSLCSEADAFIGASLLSSFGLAPVLAFLVIGPMLDIKNILMMKNYLKA
                     RFISHFITIVTLVVLVYSLLIGVIL"
     gene            3436..5565
                     /locus_tag="VQ543_001884"
     CDS             3436..5565
                     /locus_tag="VQ543_001884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding transcriptional accessory protein"
                     /protein_id="HET2612553.1"
                     /translation="MDKKYEKISQDLGVMLKQIDTVLSLTAEGATIPFIARYRKDMTG
                     SLDEVAIKAIIDLDKSLTNLNDRKEAVLAKIQEQGKLTKELEEAILVAEKLADVEELY
                     LPYKEKRRTKATIAREAGLFPLARLILQNIVDLEKEAEKFVCEGFATGKEALTGAVDI
                     LVEALSEDVTLRSMTYQEVLRHSKLTSQAKDESLDEKQVFQIYYDFSETVGTMQGYRT
                     LALNRGEKLGVLKIGFEHATDRILAFFATRFKVKNAYIDEVVQQSVKKKVLPAIERRI
                     RTELTEKAEEGAIQLFSDNLRNLLLVAPLKGRVVLGFDPAFRTGAKLAVVDATGKMLT
                     TQVIYPVKPASARQIEEAKKDLADLIGQYGVEIIAIGNGTASRESEAFVAEVLKDFPE
                     VSYVIVNESGASVYSASELARQEFPDLTVEKRSAISIARRLQDPLAELVKIDPKSIGV
                     GQYQHDVSQKKLSESLDFVVDTVVNQVGVNVNTASPALLSHVAGLNKTISENIVKYRE
                     EEGKITSRAQIKKVPRLGAKAFEQAAGFLRIPESSNILDNTGVHPENYTAVKELFKRL
                     DIKDLNEEAQSKLKSLSVKEMAQELDLGPETLKDIIADLLKPGRDFRDSFDAPVLRQD
                     VLDIKDLVVGQKLEGVVRNVVDFGAFVDIGIHEDGLIHISHMSRKFIKHPSQVVSVGD
                     LVTVWVKKIDTEREKVNLSLLAPNETD"
     gene            5552..6001
                     /locus_tag="VQ543_001885"
     CDS             5552..6001
                     /locus_tag="VQ543_001885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000778579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SprT family protein"
                     /protein_id="HET2612554.1"
                     /translation="MKLTDYVKQVSLEDFGRAFIHHVQWNRRLRSTGGRFFPKDGHLD
                     FNPKVYQKLGMEVFRKIVRHELCHYHLYFQGKGYQHKDRDFKELLKAVDGLRFVPSLP
                     NSNSKPLKLYRCQSCQQRYQRKRRIDTKRYRCGLCRGKLLLINQPED"
     gene            6060..6332
                     /locus_tag="VQ543_001886"
     CDS             6060..6332
                     /locus_tag="VQ543_001886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HET2612555.1"
                     /translation="MNSKFYKMRRNRMISGVLAGLSDKWNFDVTLVRFLFAIFTVANF
                     GLGVIIYIILASIMPTKEEIEAEMYGTGPRKRKEAQAIDDNEGWFW"
     gene            complement(6686..6877)
                     /locus_tag="VQ543_001887"
     CDS             complement(6686..6877)
                     /locus_tag="VQ543_001887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000680763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2612556.1"
                     /translation="MKHKEHILIGLLYLLSPFIGQLLVEHTHFIGTEFTGTAYVICWL
                     SVVISIHHFSKNVLSQQQK"
     gene            7305..8063
                     /locus_tag="VQ543_001888"
     CDS             7305..8063
                     /locus_tag="VQ543_001888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000173375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2612557.1"
                     /translation="MTLLDVKHVQKIYKTRFQGNQVEALKDIHFTVEKGDYVAIMGES
                     GSGKSTLLNILAMLDKPSRGQVYLNGTDTATIKNSQASSFRREKLGFVFQDFNLLDTL
                     SVKDNILLPLVLSRRPITEMMKKLVVTAENLGINQLQEKYPYEISGGQKQRVAVARAI
                     ITEPEILLADEPTGALDSKSSAALLDVFDEINERGQTILMVTHSTAAASRAKRVLFIK
                     DGILYNQIYRGEKTERQMFQEISDTLTVMASEVN"
     gene            8065..10053
                     /locus_tag="VQ543_001889"
     CDS             8065..10053
                     /locus_tag="VQ543_001889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000489335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET2612558.1"
                     /translation="MFRLTNKLAVSNLIKNRKLYYPFALAVLLAVTVTYLFYSLTFNP
                     KIAEIRGGTTIQATLGFGMFVVTLASAIIVLYANSFVMKNRSKELGIYGMLGLEKRHL
                     ISMTFKELVVFGILTVGAGIGIGALFDKLIFAFLLKLMKLKVELVATFQTKVVITVLV
                     VFGLIFLGLMFLNALRIARMNALQLSREKASGEKKGRFLPLQTILGSISLGIGYYLAL
                     TVKDPLTALTTFFIAVLLVIFGTYLLFNAGITVFLQILKKNKKYYYQPNNLISVSNLI
                     FRMKKNAVGLATIAILSTMVLVTMSAATSIFNSSESFKKVLNPHDFGVSGQNVEKEDL
                     DKLLSQFASDKGYSVKEKEVLRYSNFGIANQEGTKLTIFEKGQNRVQPKTVFMVFDQK
                     DYENMTGQKLSLSGNEVGLFAKNEGVKEQKALTLNDHQFSVKEEFTKDFIVNHVPNQF
                     NILTADYNYLVVPDLQAFLDQFPDSAIYNQFYGGMNVNASEAEQLKVAEEYEKYLQKF
                     NAQLNTEGNYVYGSTLADASAQMSALFGGVFFIGIFLSIIFMVGTVLVIYYKQISEGY
                     EDRERFIILQKVGLDQKQIKQTINKQVLTVFFLPLLFAFLHLAFAYHMLSLILKVIGV
                     LDTTMMLIVTLSICAIFLIAYVLIFMITSRSYRKIVQM"
     gene            complement(10095..10739)
                     /locus_tag="VQ543_001890"
     CDS             complement(10095..10739)
                     /locus_tag="VQ543_001890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000234620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VIT family protein"
                     /protein_id="HET2612559.1"
                     /translation="MLRAGVLDANDGIISIAGVVIGVASATTNIWIIFLSGFAAILAG
                     AFSMAGGEYVSVSTPKDTEEAAVSREKLLLDQDRELAKKSLYAAYIQNEEFKTSAQLL
                     TNKIFLKNPLKALVEEKYGIEYEEFTNPWHAAISSFVAFFLRSLPPMLSVTIFPSDYR
                     IPATVLIVGVALLLTGYTSARLGKAPTKTAMIRNLAIGLLTMGVTFLLEQLFSI"
BASE COUNT         3348 a         2025 c         2257 g         3188 t
ORIGIN      
        1 tacttgcttc ataattcata gaactactat accatatttt gtttcgcagg aagtctaatg
       61 ctaaaatctt atcagtgaga agatttctta aagtttattc tttgtagttt catctgtatt
      121 agtacataat ttaacttaga gaaaatagga ggactaatcg aatggaatta aaagatttta
      181 cagaaaaaga acaggaaatg attaagaaaa ggcttacaat gtctaatatt agtgacaaag
      241 aaactactga gaagattctg gcgctagtcc cacaagactt gattaagcga atcccgtttt
      301 ttgtcagaaa acatgctaca acacgtacga ttaaacgtat ttcaattgaa taccctgaac
      361 tctacgctgt agctcaaaca agtggtgaga ttccagaaaa aaacgcgaag aattgcgtca
      421 gattatcaca actatctttg aacaaaagat gaataagcat agtattaagt agagaatgaa
      481 aaaatatttt attggcggtt tgggaagcaa tgcctatcat agcaaggatt ttcttcaaga
      541 actagattcg caggtctatt ttctaaatcc atatgaaaag catcttcgag atgaaacaga
      601 attgaaatca tggtttaaaa atgagattgt agaggaagaa tctatctgtc tgataggtca
      661 ttctattgga ggcgatttag ctcgttattt cgcatcggaa tttgaagaag taaagaaact
      721 gattcttttg gatggtggct atctagattt agataagatt ttacctttgg atacagagtt
      781 agaggaaact aaaaattata tcaaatctca aattatttcg gacttagatg ttcttacttc
      841 taaagaaaaa tctgaagcaa agcattggtc agaaaatatg gagaaagctg taagacagtc
      901 ctatcactgg aatgttgagt ataatagata tgagttggct ataaattatg aaaatataga
      961 agcgatactc cgcctacgga gaaaaataca agcttttaag agagaagtgg gagatacctt
     1021 gtttattagt cctcgctatc ctaatgaagc tacatggaga gaggaagccc taaaagaatt
     1081 gccagactat tttgatacta tttttttaga aaactttggc catgagcttt atactcaagc
     1141 acctaaagaa atcgctagtc taatgaatga gtggctcgct tattttctat gagctacttg
     1201 tattgctgga aatggtataa gatgaaaatc tacaagtcac taattttcat ataacaaaaa
     1261 acgaacaggc tctttttctg ttattcagaa gagaacttgt tcgtttttat cttgattttc
     1321 ttaaaaagct ctatatacat agggattttc tggtttatcg actttggtaa agctgtcgat
     1381 ttccaaggtt ggaaggtttt gtttgagttc tttatggtag tgattgacca gttttccttt
     1441 ggctgttatc caagtgttgt tttcatactg ccgggtattg cccttggtca gcaatccata
     1501 gacaccagaa tctgcgatac agtggataat gccgaatcgg aacagaaatt gactattggc
     1561 atgactgggg tcgttataga caaagcctgt aaactggatt gtcttgccct caaactcatc
     1621 tggatagtcg tagatagcct ccatgacttc catatagttt tcattagtga tctgaatact
     1681 atcttgggat aagtatttat ccgccgccgt tcgcatttcc ttttcatagg ctgattttga
     1741 aaaataagaa ctggtatctg gtttcaaata ttggcttgtc gtcccttcgc ttgtctgaat
     1801 ggctagatct gttccttccg atagggggaa atgataacct ttagcagaaa cggtctgaga
     1861 atccaagcta acagttggga aagttaagcc gatgacaagt ggaatagcca gaagagaaat
     1921 actcgtcatc ttggccaatc ggctgttcag atgactgtgg gttttgactt gcttcatcca
     1981 gatatacaat tgaacaattg ccaagataaa ggaaagcacc atggagatat aggccagata
     2041 ggaatagtgc atgttgatgt actggtttag tttgcccgac agatggaggt aaatagtcag
     2101 ttcaaaatag ccagctaaaa ctaaaaatcg aatcatagga tgactccaat caagagagaa
     2161 tagactaaga cgacaagagt tacaatcgtt atgaagtgac tgataaatcg tgctttcaag
     2221 taatttttca tcatgagaat atttttgata tccagcattg gaccaatgac gagaaaggcc
     2281 agaactggtg ccaaaccgaa actcgagaga agagaagcac ctataaaggc atccgcctca
     2341 ctacagagcg aaagaagaaa ggccaaaatc atcaagagca ggatggcaaa aagaggagtc
     2401 gcactgatag aggtcagaat ccgagtcgga acgtagacct gtattataga agcaaagagg
     2461 cagccaaata ccaaataacg ccccgtatca aaaaattcat caatggcctg cacaaagact
     2521 tgaaaaactt tttttgcaga actcaagtaa gaaaaatcat gctcatgaca agccagacga
     2581 ttttctttct gaatcggttc ttgccagaaa aatcctagaa aaattcctag tattacagcc
     2641 acaagaatgg aacccagagc tcgtaatagg gcgacatgga aggagttgcc aaaggcagaa
     2701 taggtcgcaa aaagaacaat gggattgata acaggtgctg tcacaagaaa aggaacggct
     2761 gtgtaactgg gaaccttttt ttccagaaaa cgattgatga tggggacgat tccacattca
     2821 caagaaggga aaagcatacc gacaaaggtc ccaaaaaaga ttctccccca acgatttcga
     2881 gggagaaaat gataaacctt gtcaggtgtg atataaactt caatcagccc tgagacaatg
     2941 cttcctatta gaacgaaggg aagggcttca atgataatgg agagaaaaat ggctccagtt
     3001 tgaagtacac tagatgggag ttgttgaaaa gcagtcatct agtttttctt ttctgctttg
     3061 gcttttttct ctttgtcatc agggaaagta acttgtttca aatcagggag tttagcaaac
     3121 tcttcaaaca tcttgtccaa gtcgtctcgt tttgtaaatt ttacagccat aggtgtacct
     3181 cgattctaaa gtctacctct attatactat tattttgcgg aaaagggagt tttttaattt
     3241 gttttcgata gttgatacac ttcgaaaatc tcttcaaacc acgtcagctt cgccttaccg
     3301 tatatatgtg acttatccac aacctcaaaa cagtattttg agcagcctgc ggctagcttc
     3361 ctagtttgct ttttgatttt cattgagtat gaaaaggatt ggagaaagcc ttccagcttg
     3421 tggtataata gatttatgga taaaaaatat gaaaaaatct ctcaggattt gggagtgatg
     3481 ttaaagcaaa ttgataccgt tctaagtttg acagctgaag gggcgactat tccctttatc
     3541 gcgcgttatc gcaaggacat gactggtagt ctggatgagg tggcgattaa ggctattatt
     3601 gatttggata aaagtctgac aaatctcaat gaccgtaagg aagctgtctt agctaagatt
     3661 caagaacaag gtaagttgac caaggaattg gaagaagcta tcttagttgc cgaaaaatta
     3721 gcagacgttg aagaactcta tcttccttat aaggaaaagc gtcgtaccaa ggcaaccatt
     3781 gcccgtgaag ctggactctt tcctcttgct cgtttgattt tgcagaatat agttgactta
     3841 gagaaagaag ctgaaaagtt cgtctgtgaa ggatttgcga ctggcaagga agccttgacc
     3901 ggtgcagttg atattttggt cgaagcctta tcggaagatg tgaccttgcg ttctatgact
     3961 tatcaggaag tgctgagaca ctctaaactt acttctcaag ccaaggatga aagtcttgat
     4021 gaaaagcagg tttttcagat ttattatgat ttttcagaga cagttggaac tatgcaaggc
     4081 tatcgtacct tggctctcaa tcgtggggag aaacttggtg tcttgaagat cggttttgaa
     4141 catgcgacgg accgtattct tgccttcttt gctactcgtt tcaaggtgaa aaatgcttat
     4201 attgatgaag ttgttcagca atccgttaag aaaaaggtct tgcctgctat cgagcgtcgt
     4261 attcggacag aattaactga gaaagctgaa gaaggagcta tccaactttt ttctgacaat
     4321 ctgcgcaatc tcctcttggt tgctccactg aaagggcgcg tggttcttgg atttgaccca
     4381 gcctttcgta caggtgccaa gttagctgtc gtggatgcaa caggaaaaat gctgacaact
     4441 caggttattt atcctgttaa accagcatca gctcgtcaaa tcgaagaagc caagaaagat
     4501 ttagcagatt taattggtca atacggtgta gagattattg ccattggaaa tggaacggcc
     4561 agtcgtgaaa gtgaagcttt tgtagcggaa gttctgaaag atttccctga agtcagctat
     4621 gttatcgtta atgaaagtgg tgcttctgtc tattctgcca gcgaacttgc tcgtcaggag
     4681 tttccagact tgaccgttga aaaacgctct gccatttcta tcgcccgtcg tttgcaagat
     4741 cctcttgcgg aattggtcaa aatcgatcct aagtcaattg gtgtcggtca ataccaacac
     4801 gatgtcagtc agaagaaact atctgagagt ctggactttg ttgtcgatac agtggttaac
     4861 caagttggtg tcaatgtcaa tacagctagc ccagctcttc tttcacacgt agctggactc
     4921 aacaaaacta tctctgaaaa tattgtcaaa taccgcgagg aagaaggaaa aatcacttca
     4981 cgcgcccaaa tcaagaaagt tcctcgtctg ggagccaagg cctttgagca ggctgctggt
     5041 ttccttcgta tccctgaaag tagcaatatc cttgataata caggagttca cccagagaat
     5101 tacactgcag ttaaggaact cttcaaacgt ttagatatta aagacctaaa cgaagaagcc
     5161 caaagcaaac tcaagtccct ttcagtcaag gaaatggctc aagagctaga cctcggtcca
     5221 gaaaccctta aagatatcat tgcagatctt ctcaaaccag gtcgagattt ccgtgattcc
     5281 tttgacgcac ctgtgcttcg ccaagatgtc ctagatatca aagacctagt ggtaggtcag
     5341 aagctagaag gtgttgtgcg taacgttgtt gacttcggtg ccttcgttga tatcgggatt
     5401 cacgaggacg gcttgattca tatttctcat atgagtcgca agtttatcaa acaccctagt
     5461 caagtggtgt cagttggaga tttggtgacc gtttgggtca agaaaattga tactgaacgt
     5521 gaaaaagtta atctgtcgct cctcgctcca aatgaaactg actgattatg tcaagcaggt
     5581 ttcactagaa gacttcggga gagcttttat ccatcatgtc cagtggaata ggcgtctacg
     5641 ttcgacaggt gggcgatttt tccccaaaga tgggcatctg gattttaatc ccaaggttta
     5701 tcagaaactg ggtatggagg tttttaggaa aattgtccga catgaactct gtcattatca
     5761 cctttatttc caagggaagg gctatcaaca caaggatcgg gattttaagg aactgttgaa
     5821 agcagtggat ggattaaggt ttgtaccatc cttgcccaat agtaactcta aaccactcaa
     5881 gctttatcgt tgtcaatcct gccagcaaag gtatcagcgc aagcgtagga ttgataccaa
     5941 acgctatcgc tgtggacttt gtcgaggtaa attgcttctg ataaatcagc ctgaggactg
     6001 atgaaagccg agcctccccg tgatatacta tgtctaacct agcagaaaga ggaaatatca
     6061 tgaacagtaa attttataaa atgagacgca atcgcatgat ttcaggagtt ctggcaggtc
     6121 tgtcagacaa gtggaatttt gatgttaccc tagttcgttt cttgtttgcc atttttacag
     6181 ttgcaaactt tggacttggc gtgattatct atatcatcct agcttctatc atgcctacca
     6241 aggaagaaat cgaagcagaa atgtacggaa caggcccacg taaacgcaaa gaagcccaag
     6301 ccattgacga caatgaaggc tggttttggt gaggttctac agaagatttg gaataagcaa
     6361 aaagctttaa atcaatagtc taaactgctt gatttaaagc ttttttactt ttatactcaa
     6421 taaaaatcaa agtgcaaact aggaagccag ccacaggctg taatttagtc ggcaatgtga
     6481 agttgacata gtttgcactt tgatttttga atagtattaa taatatttcg ccagcttcat
     6541 ccacaaacta tagtggattg gaactagaat agtacacctc tacttctaaa acattgttag
     6601 aaatcgattt gactatcctg atcgatttgt cctgttctta tttcatttta ttataaaagc
     6661 agtaatttaa actcagtttt ttaatctatt tttgctgctg agacaataca tttttggaaa
     6721 aatggtggat gctgataaca actgataacc agcaaataac ataagcagtg ccggtaaatt
     6781 ctgtaccgat aaagtgtgtg tgttcaacta agagctgacc gatgaatgga gagagcagat
     6841 agagaagtcc gatgagtata tgttctttgt gtttcattaa agcgcacctt ctttccttat
     6901 aggttgaacg acttgcaagt gttaaattga atggtatgtt atctaggtaa gcttactcaa
     6961 atgatagttc ccgcttcctc ctttccaaag taagcctttt catacttata ttttacaact
     7021 ttaaaaatag gaaatcaaat cattttctaa gtaattttgc ttatatttca cccaatctta
     7081 caaaaatgta agattaaagt ctcttttgta aggttaggtt atggcaagcg gtcttttttt
     7141 gatgtaaact agactcataa agaacaaagg agtaacatca tgaaacaaat cttacataag
     7201 aaaactagaa aaccaagtca caaagaaatt gagcgcgttc agctgggatg cactatgatg
     7261 caagctacat ttcatttgat gggatattaa gaaaggagat tctcatgaca cttttagatg
     7321 taaaacacgt tcaaaaaatt tataaaacac gttttcaggg caaccaagta gaagccctca
     7381 aggatattca ctttaccgtc gaaaagggtg actacgttgc catcatgggt gagtctggtt
     7441 ctggtaaatc aactcttctc aatattctag ctatgctgga taaaccaagt cgtggtcagg
     7501 tttacttgaa tggaactgac accgcaacca ttaaaaattc acaggcctct agcttccgtc
     7561 gtgaaaagtt gggctttgtc ttccaagact ttaacttgct agatactcta tctgtaaagg
     7621 acaatatctt gcttccgctt gtcttgtcaa gaagacctat tacagagatg atgaagaaat
     7681 tggtggtgac agctgagaat ctgggaataa accaattaca agagaagtac ccttacgaga
     7741 tttctggtgg ccagaaacag cgtgtagcag tagcacgcgc catcatcact gaacctgaaa
     7801 ttctccttgc ggacgaaccg acaggagctc ttgactccaa gtcatctgca gccttacttg
     7861 atgtctttga tgaaatcaat gagcgcggcc aaaccattct catggtaacc cactcaacag
     7921 cagcagctag cagagctaaa cgtgtactct ttatcaaaga cggcattctt tacaatcaaa
     7981 tctaccgtgg agagaagaca gaacgtcaga tgttccaaga aatctctgat accttgactg
     8041 tcatggcaag cgaggtgaat tagtatgttt cgattaacca ataagttagc ggtatcgaac
     8101 ttgattaaaa accgcaaact ctactatcct tttgcgctgg ctgttctctt ggcagtcact
     8161 gtcacctatc tcttttactc tctaaccttc aatcccaaga ttgctgaaat tcgtggagga
     8221 acaaccattc aggctacact tggatttggt atgtttgtcg tcacccttgc gtcagccatt
     8281 atcgttctct atgccaatag ttttgtcatg aagaaccgtt ccaaggaact aggaatttat
     8341 ggcatgttgg gcttggagaa gcgtcatctt atcagtatga cctttaagga gttagtggta
     8401 tttgggattc taactgttgg agcgggtatc ggtattggag ccttgtttga caagttaatt
     8461 ttcgctttcc tgctcaaact aatgaaattg aaggttgagc tggttgctac cttccagacg
     8521 aaagttgtca ttacagtgct tgttgtcttc ggtttgattt tcctaggcct catgttcctg
     8581 aatgcccttc gaatcgcccg tatgaatgcc ctccagctct ctcgtgagaa agctagtgga
     8641 gagaaaaaag gtcgcttcct tcctctccaa accattcttg gttccataag tttaggaatt
     8701 ggctattatc ttgcccttac ggtaaaagat cctcttacag ccttaacaac cttcttcata
     8761 gctgttttac tggttatctt tgggacttat ctcttgttta atgcagggat taccgttttc
     8821 ctccaaatct taaagaaaaa taagaaatac tattaccaac caaataatct catatctgtt
     8881 tctaacttga ttttccgtat gaagaaaaat gcagttggac tagccaccat cgctatcttg
     8941 tcaacaatgg ttttggtaac catgtcagca gcgacaagca ttttcaattc ctcagaaagc
     9001 tttaaaaaag ttctaaatcc tcatgatttt ggggtttcag ggcaaaatgt tgaaaaagaa
     9061 gacttggaca aactcttgag ccagtttgca agtgacaaag gttatagtgt caaagagaaa
     9121 gaagtacttc gttacagtaa ctttggtatt gcaaatcaag aaggaactaa gttaactatt
     9181 tttgaaaaag gacaaaaccg tgtccaacca aaaacagttt tcatggtatt tgaccaaaaa
     9241 gattatgaaa atatgactgg tcaaaaactg tctctatcag gaaatgaggt cggactcttt
     9301 gcaaagaatg agggagttaa agaacagaaa gctctaactc taaatgatca tcaattttct
     9361 gtaaaagaag aatttactaa agattttatt gtcaaccatg ttccaaatca gtttaatatt
     9421 ttgactgctg attacaatta ccttgttgta cctgatttac aagccttttt ggatcaattc
     9481 ccagattcgg ctatctataa tcagttttac ggtggtatga atgtaaatgc cagtgaagca
     9541 gaacaactca aggtcgctga ggagtatgaa aaatacttac aaaagtttaa tgctcaatta
     9601 aacactgaag gtaactatgt gtatggtagc actctagcag atgctagtgc tcagatgagt
     9661 gccctctttg gtggtgtctt ctttatcggt attttcttat ccattatctt tatggtcgga
     9721 accgttctgg tcatctacta caaacaaatt tctgaaggat atgaagaccg tgagcgcttt
     9781 attatcttgc agaaagtcgg tttagatcaa aagcaaatca agcaaaccat caacaaacag
     9841 gttttaactg tattcttcct tcctttgctc tttgccttcc tacatctagc ctttgcctac
     9901 catatgctta gtctgatttt aaaagtgatt ggtgtactgg atacgactat gatgttgatt
     9961 gtgaccttgt ctatctgcgc tatcttcctc atcgcctatg tgctgatttt catgattact
    10021 tcaagaagtt atcgcaagat tgtgcaaatg taaaaaagat acctcgactt caaaatcgag
    10081 gtatttcttg tattctaaat gctgaaaagt tgttcgagca ggaaggtaac tcccatggtc
    10141 aagagaccaa tagcaaggtt ccgaatcata gctgttttgg ttggggcttt tccaagtcta
    10201 gcacttgtgt aaccagtgag aagaagggcc acaccgacaa taaggacggt agcagggatg
    10261 cggtaatcac ttggaaaaat ggtcactgac agcattggag gcaaacttct aaggaaaaag
    10321 gcaacgaagc tagaaatggc agcgtgccaa ggattggtaa attcttcata ctcaatccca
    10381 tatttttcct ctaccagagc cttgagtgga tttttaagaa agatcttatt agtcaagagt
    10441 tgggcagaag ttttgaattc ttcattttgg atataagcag catagaggga ttttttggct
    10501 agttccctat cttggtctag caagagtttt tctcgcgaaa cggcagcttc ctcggtatct
    10561 tttggagttg aaacggatac atattctcca ccagccattg aaaaggcacc agctaagata
    10621 gccgcaaatc ctgataaaaa gataatccag atattggtcg tggcactggc aaccccgata
    10681 accacaccag caatggaaat aattccatcg ttagcatcaa gaacacccgc acgcaggata
    10741 tttaaacgac ctgcaaaatt tgaatcaatt tcgtgatttg tttctgacgc taaatttcaa
    10801 gttcaagtta gccatcca
//
LOCUS       DAVBEO010000064        10604 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 009
            SAMEA1678075-rid20185393.denovo.064, whole genome shotgun sequence.
ACCESSION   DAVBEO010000064 DAVBEO010000000
VERSION     DAVBEO010000064.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678075
            Sequence Read Archive: ERR226392
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10604)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10604)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980207.1
            Genome Coverage       :: 150x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:50:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 72 of 147
            Pseudo Genes (incomplete)         :: 72 of 147
            Pseudo Genes (internal stop)      :: 42 of 147
            Pseudo Genes (multiple problems)  :: 32 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10604
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678075-rid20185393.denovo.064"
                     /strain="KS 009"
                     /db_xref="taxon:1313"
     gene            complement(7..1221)
                     /locus_tag="VQ543_001891"
     CDS             complement(7..1221)
                     /locus_tag="VQ543_001891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011836593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HET2612560.1"
                     /translation="MKEYNKSSKLEHVAYDIRGPVLEEAMRMRANGEKILRLNTGNPA
                     EFGFTAPDEVIHDLIMNARDSEGYSDSKGIFSARKAIMQYCQLKKFPNVDIDDIYLGN
                     GVSELIVMSMQGLLDNGDEVLVPMPDYPLWTAAVSLAGGNAVHYICDEAVEWYPDIDD
                     IKSKITSNTKAIVLINPNNPTGALYPKELLLEIIEIARQNDLIIFADEIYDRMVMDGH
                     VHTPVASLAPDVFCVSMNGLSKSHRIAGFRVGWMVLSGPKTHVKGYIEGLNMLSNMRL
                     CSNVLAQQVVQTSLGGHQSVDELLLPGGRIYEQRNFIYNAIQDIPGLSAVKPKAGLYI
                     FPKIDRNMYRIDDDEQFVLDFLKQEKVLLVHGRGFNWQEPDHFRIVYLPRVDELAQIQ
                     EKMTRFLKQYRR"
     gene            complement(1377..1670)
                     /locus_tag="VQ543_001892"
     CDS             complement(1377..1670)
                     /locus_tag="VQ543_001892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009014348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2612561.1"
                     /translation="MMKNSFQKSNFLYYGIILVSVLVKVIMICQLESLVPLLYPSFIG
                     FLVFHVLYHLILFLVAKRSGRWDYLMIWGLFLMFNLLYDSFLGLLFLGLSFGM"
     gene            1832..2284
                     /locus_tag="VQ543_001893"
     CDS             1832..2284
                     /locus_tag="VQ543_001893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000079155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HET2612562.1"
                     /translation="MAQRYQNIMVAIDGSKEADLAFVKGVHSALRNDAKLTIAHVIDT
                     RALQSVSTFDAEVYEELQVDAESLMKEYEKRAKDAGVADVHIVIEMGNPKTLLARTIP
                     DAEEVDLILVGATGLNAFERLLVGSSSEYILRHAKVDLLVVREQEKTL"
     gene            complement(2319..3707)
                     /locus_tag="VQ543_001894"
     CDS             complement(2319..3707)
                     /locus_tag="VQ543_001894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000453140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HET2612563.1"
                     /translation="MEVKAVFFDIDGTLVNNRKSVLKSTKDAIKIVKEQGVLVGVATG
                     RGPFFVKELMDDLDLDFAVTYNGQYIFSKDRVLFTSPISKLHLRHLISYAKKEGTEIA
                     LGTKDAMLGSKIMSFGLGSFSQRISRFVPSVLTRTVSQSFNRMVSKVVPQKEEDLLHL
                     MNQPIYQVLMLMTPEESEKAAADFEDLKLTRSNPFASDVINQGNSKLEGIRRVGKEYG
                     FDLNQVMAFGDSDNDLEMLAGVGMSVAMGNGSSSVKEAAKHITTSNQQDGIHKALEHF
                     GVLSSEKVFVSRDYHFNKVKTFHHMMDERTQEEPRAWDLEGATHRAGFKIEELVEFVR
                     AASPSEEDFGQAVSQLHQALDKAAGKVAKKTPAQQDLIGQVDALIDTLYFTYGSFVLM
                     GVDPERIFDIVHQANMGKIFPDGKAHFDPVTHKILKPDNWEEKYAPEPAIKKELQRQL
                     KAYERHKERNKS"
     gene            3773..4735
                     /locus_tag="VQ543_001895"
     CDS             3773..4735
                     /locus_tag="VQ543_001895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparaginase"
                     /protein_id="HET2612564.1"
                     /translation="MPKKILVLHTGGTISMQADASGAVVTSSDNPMNHVSNPLEGIQV
                     HALDFFNLPSPHIKPKHMLVLYQKIKEEADNYDGVVITHGTDTLEETAYFLDTMEVPH
                     MPIVLTGAMRSSNELGSDGVYNYLSALRVASDDRAADKGVLVVMNDEIHAAKYVTKTH
                     TTNVSTFQTPTHGPLGLIMKQEILYFKTAEPRVRFDLDHIQGLVPIISAYAGMTDELI
                     DMLDLEHLDGLIIQAFGAGNIPKETAQKLESLLQKGIPVALVSRCFNGIAEPVYAYQG
                     GGVQLQKAGVFFVKELNAQKARLKLLIALNAGLTGQALKDYMEG"
     gene            complement(4732..4923)
                     /locus_tag="VQ543_001896"
     CDS             complement(4732..4923)
                     /locus_tag="VQ543_001896"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2612565.1"
                     /translation="MNTIERTRRLVKGCATHCFEVVDETDEVSSKHVFEVVDRTDEVS
                     NHTYGRATLTWFAEIFEEY"
     gene            complement(4987..5997)
                     /gene="ccpA"
                     /locus_tag="VQ543_001897"
     CDS             complement(4987..5997)
                     /gene="ccpA"
                     /locus_tag="VQ543_001897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000990602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="catabolite control protein A"
                     /protein_id="HET2612566.1"
                     /translation="MNADDTVTIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEV
                     IDRLDYRPNAVARGLASKKTTTVGVVIPNITNGYFSSLAKGIDDIAEMYKYNIVLANS
                     DEDNEKEVSVVNTLFSKQVDGIIYMGYHLTDKIRSEFSRSRTPIVLAGTVDVEHQLPS
                     VNIDYKQATIDAVSYLAKENERIAFVSGPLVDDINGKVRLVGYKETLKKVGITYSEGL
                     VFESKYSYDDGYALAERLISSNATAAVVTGDELAAGVLNGLADKGVSVPEDFEIITSD
                     DSQISRFTRPNLTTIAQPLYDLGAISMRMLTKIMHKEELEEREVLLPHGLTERSSTRK
                     RK"
     gene            complement(6422..7021)
                     /locus_tag="VQ543_001898"
     CDS             complement(6422..7021)
                     /locus_tag="VQ543_001898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET2612567.1"
                     /translation="MKVLVAEDQSMLRDAMCQLLTLQPDVESVLQAKNGQEAIQLLEK
                     ESVDIAILDVEMPVKTGLEVLEWIRSERLETKVVVVTTFKRAGYFERAVKAGVDAYVL
                     KERSIADLMQTLHTVLEGRKEYSPELMEVVMTRPNPLTEQEIAVLKGIARGLSNQEIA
                     DQLYLSNGTIRNYVTNILSKLDAGNRTEAANIAKESGWL"
     gene            complement(7022..8119)
                     /locus_tag="VQ543_001899"
     CDS             complement(7022..8119)
                     /locus_tag="VQ543_001899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001848091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HET2612568.1"
                     /translation="MLERLKSIHYMFWASLIFMIFPILPVVTGWLSAWHLLIDILFVV
                     AYLGVLTTKSQRLSWLFWGIMLIYVAGNTAFVAVNYIWFFFFLSNLLSYHFSVRSLKS
                     LHVWTFLLAQVLVVGRLLIFQRIEVEFLVYLLGILTFVDLMTLGSVRIRLVEDLKEAQ
                     TKQNTQINLLLAENERNRIGQDLHDSLGHTFAMLSVKTDLALQLFQIQAYPQVEKELR
                     EIQQISKESMREVRTIVENLKSRTLTSELETVKKMLEIAGIEVEIANQLDTASLTQEL
                     ESTASMILLELVTNIIKHAKASKAYLKLERTDQELLLMVRDDGKGFETVTENELHTVR
                     ERVLPFSGEVSVISQKHPTEVQVRLPYKERK"
     gene            complement(8119..8856)
                     /locus_tag="VQ543_001900"
     CDS             complement(8119..8856)
                     /locus_tag="VQ543_001900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004249339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET2612569.1"
                     /translation="MKRWIALNKIEFLLTKRQSVYYLLSVGMPTAFYLFFSGMYQDTP
                     GGPANFMRDYLISMTAFSMMSTAIFSFPAVLHTDKMNNWQKTLRHSPVNMVEYYLSKI
                     TSMMVDYLVSILVVFSVGHLVRGVDMSLGSWIGAAFLLIVGSIAFVALGLTLTLLPSS
                     QLMSVVGNLLYLGLAVLGGLWMPISLFPDWMQAIGKCLPTYQLMELLKTFLNEGSINL
                     SATVYLLVFSAVLFGLTIYLQGHKENA"
     gene            complement(8858..9742)
                     /locus_tag="VQ543_001901"
     CDS             complement(8858..9742)
                     /locus_tag="VQ543_001901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2612570.1"
                     /translation="MNMIKVQGLHKNIKSKAILKDISFEVAEGECVALIGPNGAGKTT
                     LLDCLLGDKLVTSGQVYIQDLPVTSSKLDYTRSYLPQENVIVQKLKVKELIAFFQRIY
                     PNPLNNQEIDQLLQFDQQQKEQFAEKLSGGQKRLLSFILTLIGRPKLVFLDEPTAAMD
                     TSTRQRFWEIVRDLKAQGVTILYSSHYIEEVEHTADRILVLNKGELIRDTTPLAMRSE
                     EIEKHFILPLAYKEVVEKSVLVENWVQKQDALQVVTCEADAFWELLVQAGCRIQEIEV
                     NNRSLLDTIFEETQKGDD"
     gene            complement(9729..9923)
                     /locus_tag="VQ543_001902"
     CDS             complement(9729..9923)
                     /locus_tag="VQ543_001902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000750983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2612571.1"
                     /translation="MKKAILFLFIGLSLVVWLVEMFTGWFDQSFLHQVIRGAWGLGFM
                     ISVVFPMGMEWLKGEYYEHD"
     gene            complement(9920..10126)
                     /locus_tag="VQ543_001903"
     CDS             complement(9920..10126)
                     /locus_tag="VQ543_001903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000503440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2612572.1"
                     /translation="MEEEEMRNKMIIAVSLVVAGVMTYLMFSGLDEGFYHFPWELFAS
                     FGIMSWLIREGLKLVRDVKKELEK"
BASE COUNT         3213 a         2412 c         1931 g         3048 t
ORIGIN      
        1 caagccctat ctacgatact gtttcaagaa acgagtcatc ttttcttgga tttgggctaa
       61 ctcatcaaca cgaggaaggt aaacgatacg gaagtggtct ggttcctgcc agttaaagcc
      121 tcgaccatga accaagagaa ccttttcctg cttcaagaaa tcaaggacaa actgctcatc
      181 atcatcgata cggtacatat tgcggtcgat ttttgggaag atatagagcc ccgccttggg
      241 tttaacggca gacaaacctg gaatatcttg aatggcatta tagatgaaat ttctttgctc
      301 gtagattcgt ccaccaggaa gaagcaattc atcgactgat tggtgacccc ccaaggaagt
      361 ttgtacgact tgttgggcca aaacgttaga gcaaaggcgc atattggaca gcatattgag
      421 cccttcgata tagcccttaa catgagtctt agggccagac aagaccatcc aacccacacg
      481 gaaacctgct atgcggtggg attttgacag accattcatg ctgacacaga agacatctgg
      541 tgccaagctc gccacaggcg tatgcacatg tccgtccatt accatgcggt catagatttc
      601 atccgcaaag ataatcaaat cgttttgacg ggcaatctca ataatctcca gcaagagttc
      661 cttaggataa agggctccag ttgggttatt tggattgata aggacaattg ccttggtatt
      721 ggaagtgatt tttgacttga tatcgtcaat atctgggtac cattccacag cttcatcaca
      781 gatatagtga acggcatttc ctccagctag gctgacagcc gccgtccata gaggatagtc
      841 tggcattggc actaagacct catccccatt gtccaaaagc ccctgcatgg acatgacaat
      901 caactcactg acaccatttc caaggtaaat atcatcaata tctacgtttg ggaatttctt
      961 cagctggcaa tactgcatga tggccttacg ggctgagaaa atccctttgg agtcagaata
     1021 gccttcacta tcacgcgcat tcataatcaa gtcatgaatg acctcgtctg gcgctgtaaa
     1081 gccaaattct gctggatttc ctgtattcag acgtaaaatc ttttctccat tcgctcgcat
     1141 ccgcatggct tcttccaata caggaccacg gatatcataa gcaacatgct ctaacttact
     1201 agacttgtta tattctttca tcttgtttcc tcaattcatc aggatagtaa cattatacca
     1261 ctagaaagag aatgcgacaa gtttactgaa atgtgttact agtttcgtat agaagaaaaa
     1321 ccttgctaaa ggcgaggtta agaacgtaga gatagcaggc attttgcaaa gacacatcac
     1381 ataccaaaag ataaacctag aaaaagcaag cctagaaagg agtcataaag aagattaaac
     1441 atgaggaaaa gcccccatat catcaagtaa tcccaacgcc cacttcgttt tgcaactaga
     1501 aataagatta gatggtagag tacatgaaag actaaaaatc caataaaact tggataaaga
     1561 agcggtacca gactctctaa ttgacagatc atgatcactt ttaccaagac tgaaactagg
     1621 ataattccat aatacaggaa atttgatttt tgaaaagagt ttttcatcat tctcccttcc
     1681 ttcacttctt tccttctatc ctttctttta ttttatcata tatttatata gattttaagc
     1741 cctaatattc ttttgaaaaa tacttttttt gctttacttc tatagtgaaa aggtttacaa
     1801 ttatagtaag aaaatttcag gaggtttcat tatggcacaa cgttaccaaa atatcatggt
     1861 cgcaatcgat ggttctaagg aagcggactt ggcttttgtc aagggagttc attctgctct
     1921 acgaaacgac gctaaactca ccatcgcaca tgtcattgac acacgcgctc tccaaagcgt
     1981 atccaccttt gatgctgaag tttacgaaga actccaagtc gacgctgaaa gtctgatgaa
     2041 agagtacgaa aaacgtgcta aagatgctgg ggtagcagat gttcatatcg tcattgaaat
     2101 gggaaatcca aagaccctgc tagcacgtac tattccagat gccgaggaag tggacctcat
     2161 cctcgttggc gcaactggtc tcaacgcctt tgaacgcctc ttggtcggct cttcatctga
     2221 atacatactc cgccatgcta aggtcgattt gctggttgtg agagaacaag aaaaaacctt
     2281 ataatcacaa agaaaaggag cccctagctc ctttttgttt acgatttatt tctctcttta
     2341 tggcgttcgt aagccttgag ctggcgctgc agttcctttt taatagcagg ttctggagca
     2401 tatttttctt cccaattatc tggttttaag attttatggg tcactggatc aaaatgagcc
     2461 ttgccatctg gaaaaatttt ccccatattg gcctgatgga caatatcaaa aatacgttct
     2521 gggtccaccc ccatcaagac aaaactgccg taggtgaagt aaagcgtgtc aatcaaggca
     2581 tccacttgcc ctatcaaatc ttgctgagca ggtgtcttct tggctacttt acctgctgcc
     2641 ttatcaaggg cctgatgaag ttgcgataca gcttgaccaa aatcttcttc agaaggactg
     2701 gctgctcgaa caaactccac caattcttct attttaaaac cagccctatg ggttgcaccc
     2761 tctaaatccc aagctcgagg ttcttcttgg gttcgttcat ccatcatgtg gtggaaggtc
     2821 ttgaccttat tgaaatgata gtcacggctg acaaagactt tttctgaaga caaaacacca
     2881 aaatgttcca aggccttgtg gatcccatct tgttgattgc tagtggtaat gtgcttggca
     2941 gcttccttga cactgctact accatttccc atagcgaccg acataccgac gccagccagc
     3001 atttcaaggt cattatctga gtcaccaaaa gccatgactt ggttgaggtc aaagccatat
     3061 tctttcccaa ctcggcgaat gccttctaat ttagaatttc cctgattgat gacatccgat
     3121 gcaaaaggat tgctacgtgt caatttcaag tcttcaaaat cagctgccgc cttctcagat
     3181 tcttctggtg tcatcagcat caaaacttgg tagataggct gattcatcag gtgaagcagg
     3241 tcctcttcct tttggggaac aaccttgctg accatgcgat taaaagactg actcaccgtc
     3301 cgagttaaaa cagagggaac gaagcgacta attcgttggg aaaaagaacc cagaccaaag
     3361 gacatgattt tagaacccaa catggcatcc ttggtcccta gggcaatctc cgtgccctct
     3421 tttttagcat agctaattag atggcgcaaa tgtaacttgg aaatagggct cgtgaacaag
     3481 actctgtctt tactaaagat atactggcca ttataggtta ccgcaaaatc cagatccaaa
     3541 tcgtccatca attccttaac aaaaaaaggt cctcgccctg tcgctacgcc aactagtacc
     3601 ccttgttctt tgacaatctt aatcgcgtcc ttagtggatt tcaaaacact cttgcgattg
     3661 ttgaccaagg ttccatcgat atcaaaaaaa acagctttga cttccatcct attccaatct
     3721 ccccttttgt gatacaatga ttataccaca tttcagaaag agtgagtaaa tcatgcctaa
     3781 gaaaatcctt gttttacata cgggtggaac tatttccatg caggccgatg cttctggcgc
     3841 tgttgtgacg agttcagata atcccatgaa ccatgtgtcc aacccacttg aaggaatcca
     3901 agtccacgcc ttggactttt ttaaccttcc aagtccccat atcaaaccca aacatatgct
     3961 ggtcctctac cagaaaatta aagaggaagc agataactac gatggagtgg taatcacaca
     4021 cggaaccgat actttagagg aaacagccta tttccttgat accatggaag ttccccatat
     4081 gcctatcgtt ctaacaggag ccatgcgtag ctccaatgag ctcggtagtg atggtgttta
     4141 taattaccta agtgctttac gagtggccag cgatgacagg gctgctgaca aaggagtttt
     4201 ggtcgttatg aacgatgaaa tccacgctgc caagtatgtc accaaaacac atacgactaa
     4261 tgtcagcacc ttccagactc caacacatgg ccccctcggt ctcatcatga aacaggaaat
     4321 cctctacttc aaaacagctg aacctcgtgt tcgctttgac cttgatcaca tacaaggttt
     4381 agtccctatc atctcggctt atgctggtat gacagatgag ctgattgata tgctggattt
     4441 agaacacttg gacggtttga ttatccaagc cttcggagct ggtaatattc ccaaagaaac
     4501 ggctcaaaaa ttagaaagcc ttctgcaaaa aggaatccca gtcgctctgg tatcacgatg
     4561 ctttaacggt attgccgagc ctgtttatgc ctaccagggt gggggcgtac agttgcaaaa
     4621 agcaggcgtt ttctttgtta aagaactcaa cgcccaaaaa gctcgcttga aactcctcat
     4681 cgccctcaat gccggactaa caggacaggc tttgaaagac tatatggaag gctaatactc
     4741 ttcgaaaatc tctgcaaacc acgtcagagt cgccctaccg tatgtatggt tactgacttc
     4801 gtcagttcta tctacaacct caaaaacatg ttttgagctg acttcgtcag tttcatctac
     4861 aacctcaaaa cagtgtgttg cgcagccttt aaccagccgc ctagtccgct ctatggtatt
     4921 cattaagtca acatctcttg tttaagagca caaaatcagg aaatcttctc gattccctga
     4981 ttttttctat ttacgttttc gtgttgagct acgttctgtc aaaccatgag gtaagagaac
     5041 ttcacgttct tccaactctt ccttatgcat aatcttggtc aacatacgca tactaatggc
     5101 accaaggtca taaagaggtt gggcaatcgt tgtcaagttt ggacgggtaa agcgtgagat
     5161 ttgtgaatca tcactagtaa taatttcaaa atcttctggc acagaaacac ccttatcagc
     5221 caaaccgttc aagactcctg ctgccaactc atcacctgtc acaactgctg cagttgcatt
     5281 tgatgaaatc aaacgctctg ctaaggcgta accatcatca tagctatatt tagattcaaa
     5341 taccaaaccc tcactataag tgattcctac ttttttcaag gtttccttgt agccaactaa
     5401 acgaacctta ccattgatgt catccactag cggaccgcta acgaaagcaa tacgctcatt
     5461 ttctttagca aggtagctca ctgcatcaat tgttgcttgc ttatagtcaa tattgacact
     5521 tggcaactgg tgctcaacat cgacagttcc tgcgagaaca atcggagtac gtgaacgcga
     5581 aaattctgag cgaattttat ctgtcaagtg ataacccata tagataatgc catctacctg
     5641 ctttgaaaag agggtattga caacagaaac ttctttctcg ttatcttcat cgctattagc
     5701 taggacaata ttgtacttgt acatttctgc aatatcatca atccccttag ccaaactcga
     5761 aaaataacca ttggtaatat ttggaatcac gacaccgaca gtggttgtct ttttacttgc
     5821 aagaccacgc gcaactgcat ttggacgata atccaaacga tcaattacct ctagcacttt
     5881 tttacgggta ttctctttta catttttatt gccattgacc acacggctga ccgtcgccat
     5941 ggaaacacct gcttcacgag cgacatcata aatggttact gtatcatctg cattcattcc
     6001 ttttcctgtc ctttctatct cacacattct tttacaagta gaggtactga ttgaagctct
     6061 atatctactt acaaaagtga agatgtgaaa atttcgtttt catatttcta cttattccat
     6121 tctatcacta attgtaaaca ctttcaagtg ttttttgaag attgattgaa aaaatttcat
     6181 agaaaaccta ggtttagctc cttgctacca ccttagacta aataaaaagg aggaaactaa
     6241 gcccttctaa agttatagta aaatgaaata agaacaggat aaatcgatca ggacagtcaa
     6301 atcgatttct aacaatgttt tagaagtaga ggtgtactat tctagtttca atctactata
     6361 ggtattgttc cattcactac cgtcaatttt agcacatagt cttcatgaaa atattatatc
     6421 atcataacca accagattct tttgcgatat tagctgcctc tgttcgatta ccagcatcca
     6481 gttttgaaag aatattggtg acatagtttc gaatagttcc gtttgagagg taaagctgat
     6541 ctgcgatttc ttggttggat aagccccggg cgattccctt taagacagca atctcttgtt
     6601 ctgtcaacgg attgggacgg gtcatcacca cttccatcaa ttcaggcgaa tactccttgc
     6661 gtccttcgag gacggtgtgc aaggtttgca tgaggtctgc aatgcttcgt tcctttaata
     6721 cataagcatc cactccagcc ttgaccgcac gttcaaaata cccagcacgc ttgaaggtcg
     6781 tcaccacaac cacctttgtt tcaagccttt ctgatcgtat ccactccaag acttcaagac
     6841 ctgtcttaac aggcatttct acgtcaagga tggcgatatc tacagactcc ttttctaata
     6901 gttggattgc ttcttgccca ttcttggctt gaaggacaga ctccacatct ggttgaagcg
     6961 tgagcaattg acacatagca tctcgcaaca tactttgatc ttctgcgact aatactttca
     7021 tctactttct ctccttataa ggtagtcgaa cttgcacttc cgttggatgt ttctgactga
     7081 ttacacttac ttctcctgaa aatggaagga cacgttctcg aactgtatgg agctcatttt
     7141 ctgttacagt ttcaaaacct ttcccgtcat ctctgaccat caggagcaat tcctgatctg
     7201 tgcgttctaa ttttaagtag gctttagacg ctttagcatg tttgatgatg ttggtcacta
     7261 attcaagcaa aatcatggaa gccgttgact ctaattcctg agttaagcta gctgtatcta
     7321 gttgattagc tatttccacc tcaattccag caatttctaa catctttttc acagtctcta
     7381 gttcggatgt caaagttcta gacttaagat tttccacaat ggttcgcact tcacgcattg
     7441 attctttgct aatctgctgt atttctctta attccttttc cacttgtgga taagcctgta
     7501 tttgaaataa ctgcaaggct agatcagttt taacactaag catagcaaag gtatgcccca
     7561 gactatcatg caaatcttga ccgatacgat tgcgctcatt ttctgctagc aatagattta
     7621 tctgggtatt ttgcttagtc tgagcttctt tcaaatcctc gacaaggcga attcgaaccg
     7681 agcccaaagt catcaaatca acaaaagtaa gaattccaag cagatagact agaaactcaa
     7741 cttcgattct ctgaaaaatc aaaagtcgcc ccacaacaag gacttgagca agaagaaaag
     7801 tccagacatg taaagacttt aaactacgta cgctgaaatg ataacttaag agattggaaa
     7861 ggaaaaagaa aaaccagata taattcacag caacaaaggc ggtattccca gctacataga
     7921 tcagcatgat cccccagaaa agccaagata ggcgctggct cttagttgtt aaaacaccca
     7981 aatatgccac tacaaataga atatcaatca ataaatgcca ggcagaaagc cacccagtca
     8041 ctacaggtag gatggggaaa atcataaaaa ttaaactggc ccaaaacata tagtgtatgc
     8101 ttttcagtct ttcaagcatt aagcattctc cttatgacct tgaaggtaaa tggtcaaacc
     8161 aaacaaaact gctgaaaaaa caagtagata aactgtggct gatagattga tgctaccctc
     8221 gtttaagaag gtcttgagca actccatcaa ctgataagtt ggtaggcact tcccgattgc
     8281 ttgcatccag tctggaaata aagagatggg catccagagt ccacctaaaa cagccaagcc
     8341 tagatagaga agattgccca cgacagacat cagctgacta gaaggcaaga gtgtcaaggt
     8401 caagccaagc gctacaaaag ctatacttcc tactatcagc aagaacgcag ccccaatcca
     8461 gcttcctaaa gacatatcca cacctctgac caagtgccca actgagaaaa caaccaggat
     8521 tgagaccaaa taatcaacca tcatacttgt tatctttgat agataatatt ctaccatatt
     8581 tacagggcta tgacgcaatg ttttctgcca gttgttcatc ttatcggtat gtaagacagc
     8641 tgggaatgaa aagatagcgg tcgacatcat ggaaaaggca gtcatggaga tgaggtagtc
     8701 gcgcataaaa ttagccggtc cacctggtgt gtcctggtac atgcctgaaa agaatagata
     8761 gaaggctgtc ggcatcccta cagataataa ataatagact gattgccgtt tggtcaatag
     8821 aaattctatc ttgtttagtg caatccatcg tttcatctta gtcatctccc ttctgtgttt
     8881 cttcaaagat tgtatccaac aaactacgat tattgacttc gatttcttgt atcctacatc
     8941 ctgcttgaac taacagttcc cagaaagcat ccgcttcgca tgtgactact tgtaaggcat
     9001 cttgtttttg tacccagttt tcaaccaaga ctgacttctc aacgacttcc ttgtaagcta
     9061 gcggaaggat aaaatgcttt tcaatctcct cactacgcat agctagaggc gtcgtgtcac
     9121 gaatcaactc tcccttattt aaaaccaaaa tccggtcagc tgtatgctct acctcttcaa
     9181 tataatgaga cgaatagaga atggtgactc cttgcgcttt taggtcccga acaatttccc
     9241 aaaaacgttg acgagttgaa gtatccatgg cagcagttgg ctcatctaaa aagacaagct
     9301 ttggtcgccc aattaaggtc aagataaaag ataaaagacg cttttgccca cctgacaatt
     9361 tttctgcgaa ttgctctttc tgttgctggt caaactgtaa tagttgatcg atttcctggt
     9421 tgttcaaggg atttggatag atacgttgaa agaaagcaat caactcttta acctttagtt
     9481 tttgaacaat tacattttct tgagggagat aggatctcgt atagtctaac ttagagctcg
     9541 ttaccggcaa atcttggata tatacttgcc cactggtgac caatttatct ccaagcaaac
     9601 agtccaagag tgtcgtctta ccagctccat ttggcccaat caaggcgacg cattcacctt
     9661 cagctacctc aaaggaaata tccttcaaaa tagccttact tttgatgttt ttatgtaagc
     9721 cttgtacctt aatcatgttc ataatattct cctttcaacc actccattcc catagggaaa
     9781 acgacggaaa tcataaatcc taatccccag gcgccgcgaa taacttggtg aagaaaggat
     9841 tgatcaaacc aacctgtaaa catttctacc aaccatacca ctagtgatag tccaataaaa
     9901 agaaagagaa tcgctttttt catttttcaa gctccttttt cacatctctt actaatttca
     9961 agccttctcg tatcaaccaa gacatgattc caaagcttgc aaacaactcc caaggaaaat
    10021 gatagaatcc ttcgtccaat cctgagaaca tgagataagt catgactcct gctactacta
    10081 aactcactgc gataatcatt ttatttctca tctcttcttc ctccatttca tactacaatt
    10141 atagtctttt gaaatcagag gagatagaag cttctgtcac taaaaaatat gacaaatgtc
    10201 ataaaaaatt ctgttcaaaa caagcaagat acactataca ataaaacaca attagataaa
    10261 tctaaggcaa cttcctcaaa agagatatca aaccccattc acactataat gtaaactaat
    10321 acttatttaa agtcaaaaga gcggaaattt ttatcgtaca aacatatata ttataggtaa
    10381 gacaaaaaac tcttcaatta ctttcttaaa aatttatagg agttataaaa tctattaaat
    10441 ttcaatgtgg atacctaaac tacagtattt attgaaaaga ctggagacaa aaagtatacg
    10501 ctgccaaaat gaattgctga aaatcaaaaa agagagaagc aaactgattc tctcttaatg
    10561 tatataatat ctagttataa aaatacacac tcacatatct ctgt
//
LOCUS       DAVBEO010000065        10317 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 009
            SAMEA1678075-rid20185393.denovo.065, whole genome shotgun sequence.
ACCESSION   DAVBEO010000065 DAVBEO010000000
VERSION     DAVBEO010000065.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678075
            Sequence Read Archive: ERR226392
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10317)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10317)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980207.1
            Genome Coverage       :: 150x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:50:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 72 of 147
            Pseudo Genes (incomplete)         :: 72 of 147
            Pseudo Genes (internal stop)      :: 42 of 147
            Pseudo Genes (multiple problems)  :: 32 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10317
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678075-rid20185393.denovo.065"
                     /strain="KS 009"
                     /db_xref="taxon:1313"
     gene            <1..125
                     /locus_tag="VQ543_001904"
     CDS             <1..125
                     /locus_tag="VQ543_001904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000458116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2612573.1"
                     /translation="KASQWFKVSDKWYYVNGSGALAVNTTVDSYRVNANGEWVN"
     gene            complement(355..1335)
                     /gene="dusB"
                     /locus_tag="VQ543_001905"
     CDS             complement(355..1335)
                     /gene="dusB"
                     /locus_tag="VQ543_001905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine synthase DusB"
                     /protein_id="HET2612574.1"
                     /translation="MTNLNTPFMIGNIEIPNRTVLAPMAGVTNSAFRTIAKELGAGLV
                     VMEMVSDKGIQYNNEKTLHMLHIDEGENPVSIQLFGSDEDSLARAAEFIQENTKTDIV
                     DINMGCPVNKIVKNEAGAMWLKDPDKIYSIINKVQSVLDIPLTVKMRTGWADPSLAVE
                     NALAAEAAGVSALAMHGRTREQMYTGHADLETLYKVAQALTKIPFIANGDIRTVQEAK
                     QRIEEVGADAVMIGRAAMGNPYLFNQINHYFETGEILPDLTFEDKMKIAYEHLKRLIN
                     LKGENVAVREFRGLAPHYLRGTSGAAKLRGAISQASTLAEIEALLQLEKA"
     gene            complement(1322..2194)
                     /gene="hslO"
                     /locus_tag="VQ543_001906"
     CDS             complement(1322..2194)
                     /gene="hslO"
                     /locus_tag="VQ543_001906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000357853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp33 family molecular chaperone HslO"
                     /protein_id="HET2612575.1"
                     /translation="MDKIIKTISESGAFRAFVLDSTETVRTAQERHQTQASSTVALGR
                     TLIASQILAANEKGNTKLTVKVLGSSSLGAIITVADTKGNVKGYVQNPGVDIKKTATG
                     EVLVGPFVGNGQFLVITDYGAGNPYNSITPLISGEIGEDLAFYLTESQQTPSAVGLNV
                     LLDEEDKVKVAGGFLVQVLPGAKKEEIARFEKRIQEMPAISTLLESDDHIEALLKAIY
                     GDEAYKRLSEEEIRFQCDCSHERFMNALASLPSSDLQEMKEEDHGAEITCQFCQTTYN
                     FDEKDLEELIRDKS"
     gene            2359..3786
                     /locus_tag="VQ543_001907"
     CDS             2359..3786
                     /locus_tag="VQ543_001907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000280545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HET2612576.1"
                     /translation="MYLGDLMEKAECGQFSILSFLLQESQTTVKAVMEETGFSKATLT
                     KYVTLLNDKALDSGLELTIHSEDENLRLSIGAATKGRDIRSLFLDSAVKYQILVYLLY
                     HQQFLAHQLAQELVISEATLGRHLAGLNQILSEFDLSIQNGRWRGPEHQIRYFYFCLF
                     RKVWSSQEWEGHMQKPERKQEIANLEEICGASLSAGQKLDLVLWAHISQQRLRVNACQ
                     FQVIEEKMRGYFDNIFYLRLLRKVPSFFAGQHIPLGVEDGEMMIFFSFLLSHRILPLH
                     TMEYILGFGGQLADLLTQLIQEMKKEELLGDYTEDHVTYELSQLCAQVYLYKGYILQD
                     RYKYQLENRHPYLLMEHDFKETAEEIFHALPAFQQGTDLDKKILWEWLQLIEYMAENG
                     GQHMRIGLDLTSGFLVFSRMAAILKRYLEYNRFITIEAYDPSRHYDLLVTNNPIHKKE
                     QTPVYYLKNDLDMEDLAGIRQLLFT"
     gene            3945..5453
                     /gene="glpK"
                     /locus_tag="VQ543_001908"
     CDS             3945..5453
                     /gene="glpK"
                     /locus_tag="VQ543_001908"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000076796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HET2612577.1"
                     /translation="MSQEKYIMAIDQGTTSSRAIIFNKKGEKVSSSQKEFTQIFPQAG
                     WVEHNANEIWNSVQSVIAGAFIESGVKPNQIEAIGITNQRETTVVWDKKTGLPIYNAI
                     VWQSRQTAPLAEQLKSQGYVEKFHEKTGLIIDAYFSATKVRWILDHVEGAQERAEKGE
                     LLFGTIDTWLVWKLTDGAAHVTDYSNAARTMLYNIKELKWDDEILEILNIPKAILPEV
                     RSNSEIYGKTAPFHFYGGEVPISGMAGDQQAALFGQLAFEPGMVKNTYGTGSFIIMNT
                     GEEMQLSENNLLTTIGYGINGKVYYALEGSIFIAGSAIQWLRDGLRMVENSPESEKYA
                     RDSHNNDEVYVVPAFTGLGAPYWNQNARGSVFGLTRGTSKEDFIKATLQSIAYQVRDI
                     IDTMQVDTQTAIQVLKVDGGAAMNNFLMQFQADILGIDIARAKNLETTALGAAFLAGL
                     SVGYWKDLDELKLLNETGELFEPSMNESRKEQLYKGWKKAVKATQVFAEVDD"
     gene            5495..7321
                     /gene="glpO"
                     /locus_tag="VQ543_001909"
     CDS             5495..7321
                     /gene="glpO"
                     /locus_tag="VQ543_001909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glycerol-3-phosphate oxidase"
                     /protein_id="HET2612578.1"
                     /translation="MEFSKKTRELSIKKMQERTLDLLIIGGGITGAGVALQAAASGLE
                     TGLIEMQDFAEGTSSRSTKLVHGGLRYLKQFDVEVVSDTVSERAVVQQIAPHIPKPDP
                     MLLPVYDEDGATFSLFRLKVAMDLYDLLAGVSNTPTANKVLSKDQVLERQPNLKKEGL
                     VGGGVYLDFRNNDARLVIENIKRANQDGALIANHVKAEGFLFDESGKITGVVARDLLT
                     DQVFEIKARLVINTTGPWSDKVRNLSNKGTQFSQMRPTKGVHLVVDSSKIKVSQPVYF
                     DTGLGDGRMVFVLPRENKTYFGTTDTDYTGDLEHPKVTQEDVDYLLGIVNNRFPESNI
                     TIDDIESSWAGLRPLIAGNSASDYNGGNNGTISDESFDNLIATVESYLSKEKTREDVE
                     SAVSKLESSTSEKHLDPSAVSRGSSLDRDDNGLLTLAGGKITDYRKMAEGAMERVVDI
                     LKAEFDRSFKLINSKTYPVSGGELNPANVDSEIEAFAQLGVSRGLDSKEAHYLANLYG
                     SNAPKVFALAHSLEQAPGLSLADTLSLHYAMRNELALSPVDFLLRRTNHMLFMRDSLD
                     SIVEPILDEMGRFYDWTEEEKATYRADVEAALANNDLAELKN"
     gene            7391..8095
                     /locus_tag="VQ543_001910"
     CDS             7391..8095
                     /locus_tag="VQ543_001910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HET2612579.1"
                     /translation="MMNELFGEFLGTLILILLGNGVVAGVVLPKTKSNSSGWIVITMG
                     WGIAVAVAVFVSGKLSPAHLNPAVTIGVALKGGLPWASVLPYILAQFAGAMLGQILVW
                     LQFKPHYEAEENAGNILATFSTGPAIKDTVSNLISEILGTFVLVLTIFALGLYDFQAG
                     IGTFAVGTLIVGIGLSLGGTTGYALNPARDLGPRIMHSILPIPNKGDGDWSYAWIPVV
                     GPVIGAALAVLVFSLF"
     gene            8392..8595
                     /locus_tag="VQ543_001911"
     CDS             8392..8595
                     /locus_tag="VQ543_001911"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2612580.1"
                     /translation="MPKWSNPDYVNELDPKIVDMLVEFHKSQGTLETPEAQAEIAQKR
                     EEIEQRRAELEDKKQELLNRLNK"
     gene            complement(8682..9269)
                     /locus_tag="VQ543_001912"
     CDS             complement(8682..9269)
                     /locus_tag="VQ543_001912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2612581.1"
                     /translation="MFVFADDSLSANSKVVSGEAQFENGSSVRFGDTQVNILSDEVLE
                     VVNPDGSVDTIERRADGVYINGAFYMAYQKNEIDLNISFRSYDPNVWNYVNTIHGNKQ
                     ANTFANFMTGAGISYMIGRIGTLLGGPWGAIIGGAYFGIQAYQSYLDSQSPYPYYITS
                     TYIHVAQKKWKFITEYYRNSNYTGYVKTVTTYVNF"
BASE COUNT         3002 a         2041 c         2356 g         2918 t
ORIGIN      
        1 tgaaagcaag ccaatggttc aaagtatcag ataaatggta ctatgtcaat ggctcaggtg
       61 cccttgcagt caacacaact gtagatagct atagagtcaa tgccaatggt gaatgggtaa
      121 actaaaccta atataactag ttaatactga cttcctgtaa gaactcttta aagtattccc
      181 tacaaatacc atatcctttc agtagataat atacccttgt aggaagttta gataaaaaaa
      241 taactctgta atctctagcc ggatttatag cgctagagac tacggagttt ttttgatgag
      301 gaaagaatgg cggcattcaa gaggctcttt aagagagtta cgggttttaa actattaagc
      361 cttctccaat tgcaagaggg cttcaatctc tgccagggtg ctagcttgcg aaatggctcc
      421 acggagtttg gcagcgccag atgttccacg gagatagtga ggagcgaggc cgcggaattc
      481 acgaactgcg acgttttctc ctttgaggtt aatcaatcgt ttcaagtgtt cgtaggcgat
      541 cttcatcttg tcttcaaagg tcaaatcagg taggatttct cctgtttcaa agtaatggtt
      601 gatttggttg aagaggtaag gatttcccat ggcagctcgg ccaatcatga ctgcgtcagc
      661 accaacttct tcgatgcgtt gcttggcttc ttggacagta cggatatcac cgttggcgat
      721 gaatggaatc ttggttagag cttgggcaac cttgtaaagg gtctcaaggt ctgcgtggcc
      781 agtatacatt tgttcacggg tacggccatg catggcgagg gcagaaacac ctgcagcctc
      841 agcagcgagg gcattttcta ctgcaagaga tgggtccgcc catccggtac gcattttgac
      901 agtaagtggg atatcaagga cagactggac cttgttgatg atagagtaga tcttgtcagg
      961 atccttgagc cacatagctc cagcttcgtt cttcacgatt ttgttgacag ggcagcccat
     1021 gttgatatcg acgatatcgg tcttggtgtt ttcttggatg aattctgctg cgcgtgctag
     1081 gctgtcttca tcgctaccaa aaagttggat agagacaggg ttttcgccct catcgatatg
     1141 aagcatgtgc agggtttttt cgttgttgta ttggattccc ttgtcagaga ccatttccat
     1201 tacaacgagt ccagctccga gctcttttgc gatggtacga aaggctgagt tggtcacgcc
     1261 agccataggc gctaaaacgg tacgattggg aatctcaata ttgccaatca taaaaggtgt
     1321 attaagattt gtcacgaatg agttcctcca ggtccttttc atcaaagttg taagtagttt
     1381 ggcagaattg acaagtgatt tctgccccgt ggtcttcctc tttcatttcc tgtaagtctg
     1441 agcttggaag gctggcaaga gcgttcataa agcgttcatg gctacagtca cattggaaac
     1501 ggatttcttc ttcagaaaga cgcttgtagg cttcgtcccc gtagatagcc ttgaggaggg
     1561 cttcgatatg gtcgtcgctt tcgagaagag tagagatagc tggcatttct tggatgcgtt
     1621 tttcaaagcg agcaatctct tctttcttgg ctcctggcaa gacttgaact aggaaaccac
     1681 ctgcaacctt gaccttgtct tcctcgtcca aaaggacatt gaggccgacc gctgaaggcg
     1741 tttgttggct ttcagtaagg taaaaggcaa ggtcttcacc gatttctcca gagatgaggg
     1801 gagttataga gttgtaagga tttccagcac cgtagtctgt gataacgagg aattgaccat
     1861 ttccaacaaa aggtccgact aggacttcac cagtcgcagt ctttttgatg tcaacaccag
     1921 gattttgaac atagcctttg acgttcccct tggtatcagc gacggtgata atagcaccta
     1981 gagagctaga gcccaacacc ttaactgtaa gtttggtatt tcctttttca ttggctgcga
     2041 gaatctggct agcgataaga gttcgaccaa gcgctacagt tgagctagct tgggtttgat
     2101 gtctttcttg agcagtgcgg acggtttccg tgctatcaag gacaaaagca cgaaaggctc
     2161 cgctttctga tatagtttta ataattttat ccatagctac tattttagca taaaaatgcc
     2221 caaaggggga gccgtgtgtt tactgatttt caggataatg gaccaggaaa tcagcatgaa
     2281 aataaaaaga gaaacagatt atttcagcat ttgtaagatt tatgctatgc ttaaggtaga
     2341 aaatgaaagg ggtaacaaat gtatttagga gatttgatgg agaaagccga gtgtggtcaa
     2401 ttttcaatcc tttcctttct attacaagag tctcagacga ccgtcaaggc tgtaatggaa
     2461 gaaacaggat tttcaaaagc aaccctaacc aaatatgtca ccctgctcaa tgacaaggct
     2521 ttggatagtg gcttagaact gactattcac tcagaagatg aaaatctgcg tctgtctatc
     2581 ggtgcagcta ccaaggggag agatattcgg agcttgtttt tggatagtgc tgttaaatac
     2641 cagattttgg tttatcttct ctaccaccaa cagtttttag cccatcagct ggctcaagaa
     2701 ttggtgatta gcgaggctac gcttggtcgt cacttggctg gtttaaatca gattttgtca
     2761 gaatttgatt tatccatcca aaatggacgc tggagaggtc cagagcatca gattcgctat
     2821 ttctatttct gtcttttccg aaaggtctgg tcgagtcagg aatgggaagg tcacatgcag
     2881 aaaccagaga gaaaacagga gattgccaat ttagaggaaa tctgcggtgc aagtttgtct
     2941 gcggggcaga aattggactt ggttctctgg gctcacatca gtcaacaacg tcttcgggtc
     3001 aatgcttgtc agtttcaagt catagaagag aaaatgcgag ggtattttga caatatcttt
     3061 tatcttcgtt tgctgagaaa ggttccgtcc ttttttgctg ggcaacatat tccactagga
     3121 gttgaggatg gtgagatgat gatattcttc tcttttctcc tatctcatcg cattcttcct
     3181 cttcatacta tggagtatat tcttggtttt ggagggcagt tggcagattt actgacgcaa
     3241 ttgattcaag aaatgaagaa ggaggaacta ttgggggatt atacagagga ccatgtcacc
     3301 tatgaactca gtcagctttg tgctcaagtc tatctctata agggctatat tttacaggat
     3361 cgctacaagt accagttaga gaatcgtcat ccatatttac tgatggaaca tgattttaaa
     3421 gagacagcag aggagatttt tcatgctcta cctgcttttc aacaggggac agatttagat
     3481 aagaagattc tctgggaatg gctccagtta atcgaatata tggctgaaaa cggtggccag
     3541 catatgcgga ttggtctgga tttgacatct ggttttcttg tcttttcaag gatggcagcc
     3601 attttgaaac ggtatttgga atacaatcgt tttattacca ttgaagctta tgaccctagt
     3661 cggcattatg atttgctggt taccaataac ccgattcata agaaggaaca gacaccagtc
     3721 tattatttaa aaaacgactt ggatatggaa gatttggcag ggattcgtca gttattattc
     3781 acttaaaagg cttggttaat ctaggtcttt tttgtgaaat tcacacaatc tcctcacatt
     3841 tttttaaaaa ttaaaaaaag ttgataaaca agaaagcgct ttattttgta tactagtaag
     3901 tgtaaagagg aaacacctca agatctttat caggaggaca gtacatgtca caagaaaaat
     3961 acatcatggc cattgaccag ggaactacaa gttctcgtgc catcattttc aacaaaaaag
     4021 gggaaaaggt tagctcgagt caaaaagagt ttacccagat tttccctcag gcaggttggg
     4081 ttgagcacaa tgccaatgaa atttggaact ctgttcagtc agttattgcg ggtgctttca
     4141 tcgaaagtgg tgtcaagcca aatcaaatcg aggcaatcgg gattaccaac caacgtgaaa
     4201 caacggttgt ctgggataag aaaacaggac ttcctatcta caatgctatc gtttggcagt
     4261 cacgccagac agcacctttg gctgagcaac taaaaagcca aggttatgtg gaaaaattcc
     4321 atgaaaagac tggtttgatt attgatgctt acttctctgc taccaaggtt cgttggattt
     4381 tggatcatgt agaaggtgct caagagcgag cagaaaaagg ggaattgctc tttggtacta
     4441 tcgatacttg gttggtttgg aaattgactg acggtgcggc tcacgtgact gactactcaa
     4501 atgcagctcg taccatgctt tataacatta aagaactcaa atgggatgat gagattttgg
     4561 aaatccttaa cattccgaag gctatacttc cagaagttcg ttctaactcc gaaatctacg
     4621 gcaagacagc tccattccat ttctacggtg gagaggtgcc aatctcaggt atggctgggg
     4681 accaacaagc agccctcttt ggacagttgg cttttgagcc aggtatggtt aagaatactt
     4741 atggaacagg ctctttcatc atcatgaata ctggggaaga gatgcagttg tctgaaaaca
     4801 acctcttgac aaccattggt tacggaatca acggtaaggt ttattatgcc ttggaaggtt
     4861 ctatcttcat cgcaggaagt gctattcagt ggcttcgtga cggtcttcgc atggttgaaa
     4921 attcaccaga atctgaaaaa tacgctcgtg attctcacaa caacgatgaa gtttatgtcg
     4981 ttccagcctt tacaggtcta ggcgctccat actggaacca aaatgctcgt ggttccgtct
     5041 ttggtttgac tcgtggaaca agcaaagaag actttatcaa ggcgactttg caatctattg
     5101 cttatcaagt gcgtgatatc atcgacacca tgcaagtgga tactcagacc gccattcaag
     5161 tactgaaggt ggatggtggt gcagccatga acaacttcct catgcagttc caggcggata
     5221 ttttaggcat tgacattgca cgtgctaaaa acctggaaac aacagctcta ggagcggcct
     5281 tcctagcagg tttgtcagta gggtactgga aagacttgga cgagttgaaa ctcttgaacg
     5341 agacaggaga actctttgag ccatctatga acgaatctcg caaggaacaa ctctacaagg
     5401 gctggaagaa ggctgtgaaa gcaactcaag tctttgcgga agtagacgac taatactggc
     5461 agaataaagc gatttattta gaaagtgtgt aaatatggaa ttttcaaaga aaacacgtga
     5521 attgtcaatt aaaaaaatgc aggaacgcac cctggacctc ttgattatcg gtggaggaat
     5581 cacaggagct ggtgtagcct tgcaggcggc agctagcggt cttgagactg gtttgattga
     5641 aatgcaagac tttgcagaag gaacatctag tcgttcaaca aaattggttc acggaggact
     5701 tcgttacctt aaacaattcg acgtagaagt ggtctcagat acggtttctg aacgtgcagt
     5761 ggttcaacaa atcgctccac acattccaaa accagaccca atgctcttac cagtttacga
     5821 tgaagatgga gcaaccttta gcctcttccg tcttaaagta gccatggact tgtacgacct
     5881 cttggcaggt gttagcaaca caccaactgc gaacaaggtt ttgagcaagg atcaagtctt
     5941 ggaacgccag ccaaacttga agaaggaagg cttggtagga ggtggagtgt atcttgactt
     6001 ccgtaacaac gatgcgcgtc tcgtgattga aaacatcaaa cgtgccaacc aagacggtgc
     6061 cctcattgcc aaccacgtga aggcagaagg cttcctcttt gacgaaagtg gcaagattac
     6121 aggtgttgta gctcgtgatc tcttgacaga ccaagtattt gaaatcaagg cccgtctggt
     6181 tattaataca acaggtcctt ggagtgataa agtacgtaat ttgtctaata agggaacgca
     6241 attctcacaa atgcgcccaa ctaagggagt tcacttggta gtggattcaa gcaaaatcaa
     6301 ggtttcacag ccagtttact ttgacacagg tttgggtgac ggtcgtatgg tctttgttct
     6361 cccacgtgaa aacaagactt actttggtac aactgataca gactacacag gtgatttgga
     6421 gcatccaaaa gtaactcaag aagatgtaga ttatctactt ggcattgtca acaaccgctt
     6481 tccagaatcc aacatcacca ttgatgatat cgaaagcagc tgggcaggtc ttcgtccatt
     6541 gattgcaggg aacagtgcct ctgactataa tggtggaaat aacggtacca tcagtgatga
     6601 aagctttgac aacttgattg cgactgttga atcttatctc tccaaagaaa aaacacgtga
     6661 agatgttgag tctgctgtca gcaagcttga aagtagcaca tctgagaaac atttggatcc
     6721 atctgcagtt tctcgtgggt ctagcttgga ccgtgatgac aatggtcttt tgactcttgc
     6781 tggcggtaaa atcacagact accgtaagat ggctgaagga gctatggagc gcgtggttga
     6841 catcctcaaa gcagaatttg accgtagctt taaattgatc aattctaaaa cttaccctgt
     6901 ttcaggtgga gaattgaacc cagcaaatgt ggattcagaa atcgaagcct ttgcgcaact
     6961 tggagtatca cgtggtttgg atagcaagga agctcactat ctggcaaatc tttacggttc
     7021 aaatgcaccg aaagtctttg cacttgctca cagcttggaa caagcgccag gactcagctt
     7081 ggcagatact ttgtcccttc actatgcaat gcgcaacgag ttggctctta gcccagttga
     7141 cttccttctt cgtcgtacca accatatgct ctttatgcgt gatagcttgg atagcatcgt
     7201 tgagccaatt ttggatgaaa tgggacgatt ctatgactgg acagaagaag aaaaagcaac
     7261 ttaccgtgct gatgtcgaag cagctctcgc taacaacgat ttagcagaat taaaaaatta
     7321 agaaaaaata aaagaggtgg agggcagcat tccttgtcgc ccgtcccttc tttttaatgg
     7381 agacagaaag atgatgaatg aattatttgg agaatttcta gggactttaa tcctgattct
     7441 tctaggaaat ggtgttgttg caggtgtggt tcttcctaaa accaagagca atagctcagg
     7501 ttggattgtg attactatgg gttgggggat tgcagttgcg gttgcagtct ttgtatctgg
     7561 caagctcagt ccagctcatt taaacccagc tgtgaccatc ggtgtggcct taaaaggtgg
     7621 tttgccttgg gcttccgttt tgccttatat cttagcccag ttcgcagggg ccatgctggg
     7681 tcagattttg gtttggttgc aattcaaacc tcactatgag gcagaagaaa atgcaggcaa
     7741 tatcctggca accttcagta ctggaccagc catcaaggat actgtatcaa acttgattag
     7801 cgaaatcctt ggaacctttg ttttggtgtt gacaatcttt gctttgggtc tttacgattt
     7861 tcaggcaggt atcggaacct ttgcagtggg aactttgatt gtcggtatcg gtctatcact
     7921 aggtgggaca acaggttatg ccttgaaccc agctcgtgac cttggacctc gtatcatgca
     7981 cagcatcttg ccaattccaa acaagggaga cggagactgg tcttacgctt ggattcctgt
     8041 tgtaggccct gttatcggag cagccttggc agtgcttgta ttctcacttt tctagtttat
     8101 actcttcgaa aatcaaattc aaaccacgtc agcgtcgcct taccgtactc aagtacagct
     8161 tacggctagc ttcctagttt gctctttgat tttcattgag tattagaaaa caattatgtt
     8221 gatagagctt gggcaagagc ccaatttcag caaaaaatga agtaaatctt ctcataataa
     8281 aacgcatcat atcaagcacg aaaattccac gaggtcaact acagtcagaa agctgaacaa
     8341 caagccaaaa cgcccaaaaa aggcggcaaa aagcaagcac ctgcaagcaa cgtgccgaaa
     8401 tggtcaaatc ctgattatgt caacgaatta gacccaaaaa tcgttgatat gctagtagaa
     8461 tttcacaagt cacaaggcac tttggaaact cccgaggcgc aagcagaaat cgcccaaaaa
     8521 cgtgaagaaa tcgagcaaag gagagctgag cttgaggata aaaaacaaga gcttttgaac
     8581 cgcttgaaca aatagagttt cgcaagtatt atgcttacaa attacttgag caattaacta
     8641 aaatataaac cctgccttta tatctaggca gggtttatat tttagaaatt cacgtaggtt
     8701 gttacggttt ttacataccc agtatagttt gagtttctat agtattcagt gataaacttc
     8761 catttttttt gagcaacatg gatataagta cttgttatgt agtatggata tgggctttgt
     8821 gaatccaagt aagactgata agcttgtata ccaaaatatg ctccaccaat tattgcaccc
     8881 catggacccc ccaataaagt acctatccta ccaatcatat aactgattcc agcaccagtc
     8941 atgaagttag cgaatgtgtt agcttgttta ttcccatgta ttgtgttgac gtaattccaa
     9001 acattaggat cgtatgatct aaaagatata tttaggtcga tttcattctt ttgataagcc
     9061 atataaaatg ccccattgat atagacgccg tcagcacgtc gttcaatagt gtctacactt
     9121 ccatctggat tgacaacctc aagaacttca tcgcttaaaa tatttacttg cgtatctccg
     9181 aaccgcactg atgagccatt ctcaaactga gcctcaccag atacaacttt agagtttgcc
     9241 gataagctat catcagcaaa aacaaacaag cgacggggaa atgctagaca tacagaaaac
     9301 agacataact agcaaacaca tgcatttaaa catcttagac ataacggaaa ctcctttgta
     9361 tttttgattt ttttcaactt ttattataca ataaaaccaa ataaaaagaa agcggtaaca
     9421 atatgcttaa tgcgaaaatt ttttatatat ttttatgttt gatcgttatc gaaactacag
     9481 gcttgttgtt gttgaaaaga ggtctcgaaa tgggttattt agacacagaa gctattatcc
     9541 tcgcagtttt ttcatttgct ttttacaacc tatgttcatt cgcttgggtc tgctctacaa
     9601 taaaaaacaa taaaaaataa atagacgtat tttcaaaaaa aaaaaaaaaa aatgcatatt
     9661 tatcttagca aaacgacaat ttaaatcgtc gtttttttgt agtacgacgg gcatgtcgta
     9721 tatctgaggt gtaagtcctc ggtgggcacc tgctaccggt gaacccaata gcgattccca
     9781 agcctgacta tcgtgaggta gcagggagag gaagggatag cgaaatcgtg gctctacgaa
     9841 caggaacgtg atagtaaggc gtatatagcg gataaggagg cttcaaactc taaagtccaa
     9901 aaaggtagtc gtaacctata tgtgtaaatc acgagagtaa ttgaattcgg actaaggttt
     9961 gtgtgaaaaa gataaatctt tctagagtct aaagactctg cgtcagattt cctattttca
    10021 ctgtaacctt ttaacgtcct catatcttgt ataaacgagg aaagatgtac gacttatccc
    10081 gtgaggtttc atgagcgctg aaagcgtagt aacaacgaat catgagaagt cagccgagcc
    10141 catagtagtg aggaaacttc cgtaatggaa gtggagcgaa ggggtgaata ctcaaacagt
    10201 ctggggagag actgtttgag gtctgtcgct agaaagagaa aacgacagat cgaagtaatc
    10261 ctacttcact tgtgtctgta aaatgagtgg tctgatagaa ctggactttg acacgta
//
LOCUS       DAVBEO010000066        10036 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 009
            SAMEA1678075-rid20185393.denovo.066, whole genome shotgun sequence.
ACCESSION   DAVBEO010000066 DAVBEO010000000
VERSION     DAVBEO010000066.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678075
            Sequence Read Archive: ERR226392
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10036)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10036)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980207.1
            Genome Coverage       :: 150x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:50:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 72 of 147
            Pseudo Genes (incomplete)         :: 72 of 147
            Pseudo Genes (internal stop)      :: 42 of 147
            Pseudo Genes (multiple problems)  :: 32 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10036
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678075-rid20185393.denovo.066"
                     /strain="KS 009"
                     /db_xref="taxon:1313"
     gene            complement(103..1806)
                     /gene="ilvD"
                     /locus_tag="VQ543_001913"
     CDS             complement(103..1806)
                     /gene="ilvD"
                     /locus_tag="VQ543_001913"
                     /EC_number="4.2.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000137341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxy-acid dehydratase"
                     /protein_id="HET2612582.1"
                     /translation="MTELDKRHRSSIYDSMVKSPNRAMLRATGMTDKDFETSIVGVIS
                     TWAENTPCNIHLHDFGKLAKEGVKSAGAWPVQFGTITVADGIAMGTPGMRFSLTSRDI
                     IADSIEAAMSGHNVDAFVAIGGCDKNMPGSMIAIANMDIPAIFAYGGTIAPGNLDGKD
                     IDLVSVFEGIGKWNHGDMTAEDVKRLECNACPGPGGCGGMYTANTMATAIEVLGMSLP
                     GSSSHPAESADKKEDIEAAGRAVVKMLELGLKPSDILTREAFEDAITVTMALGGSTNA
                     TLHLLAIAHAANVDLSLEDFNTIQERVPHLADLKPSGQYVFQDLYEVGGVPAVMKYLL
                     ANGFLHGDRITCTGKTVAENLADFADLTPGQKVIMPLENPKRADGPLIILNGNLAPDG
                     AVAKVSGVKVRRHVGPAKVFDSEEDAIQAVLTDEIVDGDVVVVRFVGPKGGPGMPEML
                     SLSSMIVGKGQGDKVALLTDGRFSGGTYGLVVGHIAPEAQDGGPIAYLRTGDIVTVDQ
                     DTKEISMAVSEEELEKRKAETTLPPLYSRGVLGKYAHIVSSASRGAVTDFWNMDKSGK
                     K"
     gene            complement(2039..2971)
                     /locus_tag="VQ543_001914"
     CDS             complement(2039..2971)
                     /locus_tag="VQ543_001914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase family protein"
                     /protein_id="HET2612583.1"
                     /translation="MMRSTKELRHVYRDFLLEANQSDSDIVVLEADLSSSMATNNLEK
                     DFGDRYVNVGIMEAEMVGLAAGLSIQGFRPYLHTFGPFASRRVFDQLFISLGYAQLDA
                     TVIGSDAGVTAEMNGGTHMPFEEIGLLRLIPKSIIFEATDDIQFREILNQTLDLKGLK
                     YIRTIRKAPVPVYQGGEDFSKGYIELRHGEDLVIVASGIMVAPSIRVADELSKLGYSV
                     GVIDLFRIKPIPEQIKTMLSGKTIFTVENHNQIGGIGSALCELFSDDGITKIHRMGVQ
                     ERFGQVGKMDYLLNEYGLSESNIKEKVLEIYNAR"
     gene            complement(2968..3825)
                     /locus_tag="VQ543_001915"
     CDS             complement(2968..3825)
                     /locus_tag="VQ543_001915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HET2612584.1"
                     /translation="MILSKNREDGLRKFATNIRLNTLRTLNHLGFGHYGGSLSIVEVL
                     AVLYGEIMPMTPEIFAARDRDYFILSKGHGGPALYSTLYLNGFFDKEFLYSLNTNGTK
                     LPSHPDRNLTPGIDMTTGSLGQGISVATGLAYGQRIRKSPFYTYAIVGDGELNEGQCW
                     EAIQFASHQQLSNLIVFVDDNKKQLDGFTKDICNPGDFVEKFSAFGFESIRVKGSDIR
                     EIYEGIVQLKQSNNSSPKCIVLDTIKGQGVQELEEMKSNHHLRPTVEEKQMLTSVVER
                     LSQELEETE"
     gene            complement(3829..5175)
                     /locus_tag="VQ543_001916"
     CDS             complement(3829..5175)
                     /locus_tag="VQ543_001916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000975284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HET2612585.1"
                     /translation="MMKFILDIVSTPAILVALIAILGLVLQKKKLPDIIKGGIKTFVG
                     FLVVSGGAGIVQNSLNPFGTMFEHAFHLSGVVPNNEAIVAVALTTYGSATAMIMFAGM
                     VFNILIARFTRFKYIFLTGHHTLYMACMIAVILSVAGFTSLPLILLGGLALGIIMSIS
                     PAFVQKYMVQLTGNDKVALGHFSSLGYWLSGFTGSLIGDKSKSTEDIKFPKSLAFLRD
                     STVSITLSMAVIYIIVAIFAGSEYIEKEISSGTSGLVYALQLAGQFAAGVFVILAGVR
                     LILGEIVPAFKGISERLVPNSKPALDCPIVYTYAPNAVLIGFISSFVGGLVSMVIMIA
                     SGTVVILPGVVPHFFCGATAGVIGNASGGVRGATIGAFLQGILISFLPVFLMPVLGGL
                     GFQGSTFSDADFGLSGIILGMLNQFGSQAGIVIGLVLILAVMFGVSFIKKPSATEE"
     gene            complement(5188..5472)
                     /locus_tag="VQ543_001917"
     CDS             complement(5188..5472)
                     /locus_tag="VQ543_001917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008089859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HET2612586.1"
                     /translation="MLKIGTACGSGLGSSFMVQMNIESVLSDLNVSDVEVEHYDLGGA
                     DPNAADIWIVGRDLADSASHLGDVRILNSIIDMDELRELITKLCEEKGLI"
     gene            complement(5476..7506)
                     /locus_tag="VQ543_001918"
     CDS             complement(5476..7506)
                     /locus_tag="VQ543_001918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000460919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HET2612587.1"
                     /translation="MFDYRALVILMTLMDHCELSLYELSVKVSLPIKEVKEGIDYLVP
                     YLANKGIVLDKKQGRYSLSNRTKQSLTDIIKSDELVLPKSTRLALIYLYTFCRLDFIS
                     NSHYQDFLKVSKNTTLSDIQSLRKIMLDNDLELGYSRAKGYTLHGSEWNKHRLAFQMV
                     SELLESSIGIWGLDYVLSSWGYSLTYDLIDQVVKDYYEKLQLVPIVNQLKVYLFGLVF
                     ILCRYQRDVERVCLSETLVSPVIQDITTILLDTVVDLGIIDTVFSEDDYRYITVLLSS
                     CFEGEVDVAPVYFNQLTEAIISRMEDISLLHFKQREGLRENLRRHLIPAYYRLKFGLP
                     SSNEYVLHVKEHYPDLFELVKDSLMPLMDAIDNPIPDSETAYFVIHFGGYLKKADTLP
                     QKWYKAAIICPNGVSSSLMLKENLLALFPQIEFIGTSKIDDLQVKASSDYDMVFSTIK
                     VETEKPNYLVSVMMTEEQAIQLVELVLKDFPNLEYGDFEIEQILNIVKRYGIITQELE
                     LRLALKNYLYQKNDRKEIVPVLEQLITKETYQVSSQKLGWKEAIRLAAKPLLDQDKIT
                     ENYPEAMIQKVEEFGPFINLGKGVAIPHARPDEGVNEIGMSMLVLEEPIYLLDNPEQE
                     VRLLICIAAIDNESHLKALSHLTTILRDKNHVQTLISSKNYDDIKMIIKQED"
     gene            7698..8705
                     /locus_tag="VQ543_001919"
     CDS             7698..8705
                     /locus_tag="VQ543_001919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HET2612588.1"
                     /translation="MTEKLINSKPNGVFALILIELTIVLGIFIFIMGVGSENIFGIII
                     GPLLIVIAGLAHAGLKVVKPQEALVLTLFGNYTGTIKEPGFYFVNPFSVAVNPANHTR
                     LGQSGDVSTKSPFLGAKSSNDNDVNLEIGKKQISLKVMTLSNSRQKINDCLGNPVEIG
                     IAVTWRVVDTAKAVFNVDNYKEYLSLQCDSALRNIVRIYPYDVSPNVDTTGDGQADEG
                     SLRGSSEIVANRIREEIQSRVEDAGLEILEARITYLAYAPEIAAVMLQRQQASAIIDA
                     RKMIVDGAVGMVEMALERLNEGELVELDEERKAAMVSNLLVVLCGNHDAQPIVNTGSL
                     Y"
     gene            8708..8908
                     /locus_tag="VQ543_001920"
     CDS             8708..8908
                     /locus_tag="VQ543_001920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HET2612589.1"
                     /translation="MAEAKKKQIPLRLSTKLYAALASWAEDDFRSVNGQIEYLLTECV
                     KQRKKDGKYVSETIDEPFEIDI"
     gene            9060..9242
                     /gene="rpmF"
                     /locus_tag="VQ543_001921"
     CDS             9060..9242
                     /gene="rpmF"
                     /locus_tag="VQ543_001921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HET2612590.1"
                     /translation="MAVPARRTSKAKKNKRRTHYKVTAPSVNFDETTGDYSRSHRVSL
                     KGYYKGRKITKAASAE"
     gene            9258..9407
                     /gene="rpmG"
                     /locus_tag="VQ543_001922"
     CDS             9258..9407
                     /gene="rpmG"
                     /locus_tag="VQ543_001922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001265622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HET2612591.1"
                     /translation="MRVNITLEHKESGERLYLTSKNKRNTPDRLQLKKYSPKLRKHVV
                     FTEVK"
     gene            complement(9899..>10036)
                     /locus_tag="VQ543_001923"
     CDS             complement(9899..>10036)
                     /locus_tag="VQ543_001923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000753868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
                     /protein_id="HET2612592.1"
                     /translation="ESGSMATGWVTVSGKWYYTYNSGDLLVNTTTPDGYRVNANGEWV
                     G"
BASE COUNT         3252 a         2132 c         1626 g         3026 t
ORIGIN      
        1 caaaacactg ttttgaggtt gtggatagaa ctgacgaagt cagtaaccat acctacggca
       61 aggcgacgtt gacgtgattt gaagagattt tcgagtatga gtttattttt tacctgactt
      121 gtccatattc cagaagtctg tcacggctcc gcgtgaagca gatgatacga tgtgggcata
      181 tttaccgagg acaccacggc tgtaaagtgg tggcaaggtt gtttctgcct tgcgtttttc
      241 aagttcttct tcggatacgg ccatagaaat ttctttggta tcttggtcaa ccgtaacgat
      301 atcgccggta cggagatagg caattggtcc accatcctga gcttcaggag cgatatgtcc
      361 aacaaccaga ccataagtac caccagagaa acgtccgtcc gtcaagaggg ccaccttatc
      421 tccctgacct ttaccaacaa tcattgaaga aagtgatagc atctcaggca taccaggacc
      481 acctttaggt ccaacaaaac gaacaacgac tacatcgcca tcaacgattt catctgtcag
      541 aacggcctga atcgcatctt cttctgagtc aaagacctta gctggcccaa cgtgacgacg
      601 cactttaaca cctgatacct tggcaactgc accgtcagga gcaaggttcc cgttcaagat
      661 gataagcgga ccatccgcac gttttggatt ttcaagtggc atgataactt tttggcctgg
      721 agtcaagtct gcaaagtcag ccaagttttc agctacagtc ttaccagtac atgtgatgcg
      781 atctccgtga aggaaaccat ttgccaacaa atacttcata accgcaggga caccaccgac
      841 ttcgtagagg tcttggaaga catactgacc agatggtttc aagtcggcca agtgaggcac
      901 acgttcttga atcgtattga agtcctcaag tgacaagtca acatttgcgg catgggcaat
      961 ggcgagcaag tgaagagtgg cgtttgtaga accaccgaga gccatcgtta cagtgatagc
     1021 atcttcaaag gcttcacgag tcaagatatc tgatggtttg agaccaagtt ccaacatctt
     1081 aacaacagca cgtcctgctg cttcgatatc ttctttctta tcagctgatt cagctgggtg
     1141 agaggatgac cctggcaaac tcatccctag aacttcgata gcagttgcca tggtattagc
     1201 agtatacata ccaccacaac caccagggcc agggcaggca ttacattcaa gacgtttcac
     1261 gtcctcagct gtcatgtcac cgtggttcca ttttccgata ccttcaaaga cagaaaccaa
     1321 gtcgatatct ttaccatcaa gatttcccgg tgcaatagtt ccaccatagg cgaaaatagc
     1381 tgggatatcc atattagcaa tagcaatcat agatccaggc atgttcttgt cacagccacc
     1441 gatagcgacg aaggcatcca cgttgtgacc actcatagcc gcctcgatgg agtccgcgat
     1501 gatgtcacga gatgttagag agaaacgcat accaggcgtt cccatagcga tcccgtccgc
     1561 tacggtaatg gttccaaact gtacaggcca agcgcctgca gatttgacac cttctttagc
     1621 cagtttcccg aaatcatgca agtgaatgtt acatggtgta ttttccgccc aagtcgaaat
     1681 cactcccaca atcgatgttt caaagtcctt atctgtcata ccagtcgcac gaagcatagc
     1741 acggttaggt gatttaacca tgctgtcata aatgctactg cggtgacgtt tatctaattc
     1801 agtcatctta tccctcccat ttcagttttt actattatag cacaattttc gcatgaagaa
     1861 cagaataaaa ttcttgaatt ttcagaaaat tctatacaca tgtgaaatat ttaaaattaa
     1921 aaacaacaaa gcggattagt gcactttctg atgaccagaa tatgcttttt aatccgcttt
     1981 ctttaaataa cgtactgtaa tttttacaga aattctttca aataagtgta tttaacatct
     2041 atcttgcatt ataaatttct agaaccttct cttttatatt cgattcactc aaaccatact
     2101 cattaagaag ataatccatt ttccctactt gaccgaatct ttcttgaaca cccatccgat
     2161 gaatttttgt tattccatca tcagagaata attcacataa agcactgcca attccaccta
     2221 tctgattgtg gttttctaca gtaaatatag tttttccact taacattgtt tttatctgtt
     2281 ctggtatcgg tttgattcta aataaatcta tcacacctac tgaataacct aatttagaca
     2341 gttcatctgc aactcgaata cttggagcaa ccattatgcc agaagcaacg attacaagat
     2401 cttcaccatg ccttaactca atgtagcctt tagaaaaatc ttctccacct tgatacacag
     2461 gaactggagc ttttctaatt gttcgaatat attttagtcc ttttaagtct aatgtctggt
     2521 tcaatatttc acgaaattgg atatcatcag ttgcttcgaa aatgattgat ttaggaatta
     2581 aacgtaacaa tccaatttct tcaaatggca tatgtgttcc accattcatc tctgccgtta
     2641 ctcctgcatc tgatccaatc acagtggcat ccaattgtgc gtatccaaga gaaataaata
     2701 attgatcaaa tactcttcgt gaagcaaaag gaccaaatgt atgaagataa ggtctaaacc
     2761 cctgaataga caagcctgct gcaaggccga ccatttctgc ttccataatc ccaacattca
     2821 cataacggtc tccaaagtcc ttttcaagat tattagtagc catcgaactt gacaaatcgg
     2881 cttctaagac tactatatca gaatcacttt gattagcctc taaaaggaag tctctatata
     2941 catgccgtaa ttctttcgta cttctcatca ttctgtttcc tccaattcct gacttaatct
     3001 ttctacaact gaagttaaca tttgtttctc ctctacagta gggcgaagat gatgattgga
     3061 tttcatttct tccagctctt gaaccccttg acctttaata gtatctaata caatgcactt
     3121 aggtgatgaa ttatttgact gttttaattg gacaatccct tcataaattt ctctaatatc
     3181 tgaacccttg accctaatgg attcaaatcc aaatgctgaa aatttttcta cgaaatcacc
     3241 tggattacaa atatcctttg taaaaccatc taattgtttt ttgttatcat caacaaatac
     3301 aattaagttg gataactgtt gatgagaagc aaactgtata gcctcccaac attgtccctc
     3361 atttaactca ccatctccaa caatagcgta agtataaaag ggactctttc ttattctctg
     3421 accatatgca agtccagttg caacactaat tccttgtcct aaagagcccg ttgtcatatc
     3481 tatgcctggc gttagatttc tatcaggatg agacggtaat ttggttccat ttgtatttaa
     3541 agaatataag aattctttgt caaagaaacc attcaaatag agtgtactgt atagagctgg
     3601 tcctccgtga ccttttgata atatgaaata atctctatct cgtgctgcaa atatttctgg
     3661 agtcattggc attatttcac cataaagcac cgctaaaact tctacgatag acagacttcc
     3721 tccgtaatgt ccgaatccaa gatgattcaa tgttctaaga gtatttaatc ggatgttagt
     3781 cgcaaatttt cttaacccat cttctctatt tttacttaaa atcatccctt attcctccgt
     3841 tgcagatggc tttttaataa aggatactcc aaacataact gctagaataa gaacaagacc
     3901 aatcacaatg cctgcttgtg agccaaattg atttaacatt cctaaaataa ttcctgatag
     3961 accaaaatct gcatctgaga aagttgatcc ttggaaacca agtcctccca aaactggcat
     4021 taaaaagact ggaagaaaac tgattaaaat accttgtaaa aatgctccaa tagtggctcc
     4081 acgaacacca ccagatgcat tcccaatgac acctgcagtc gctccacaga agaaatgagg
     4141 cacaacacct ggtaagataa caaccgttcc tgaagcaatc ataattacca tacttactaa
     4201 accaccaaca aaactagaga taaatccaat tagaactgca ttgggtgcat aagtataaac
     4261 aatcggacaa tccaaagcag gttttgaatt aggtacaaga cgctctgaaa tacctttaaa
     4321 ggctggaaca atttcgccca aaataaggcg aacacctgct aaaataacaa atacccctgc
     4381 tgcaaattga cctgctaatt gtaaagcata aactagacca cttgtaccac tactgatttc
     4441 tttttctata tattctgacc ctgcaaagat agctacaata atgtaaataa ctgccatgga
     4501 taaagtaata ctaacagtac tatcacgtaa aaaagctaaa ctctttggaa atttaatgtc
     4561 ctctgttgat tttgatttgt caccgataag gctaccagta aaaccactca accaatatcc
     4621 caaagaactg aaatgaccta aagctacctt gtcatttcca gttaattgaa ccatatattt
     4681 ttgcacaaat gctggggaaa tactcataat aataccgagt gctaatcctc ctagtaagat
     4741 gagaggcaag ctagtaaagc cagcaactga taaaatgacc gcaatcatac atgccatata
     4801 tagagtgtgg tgccctgtta aaaaaatata tttaaatcga gtaaaacgag cgattaagat
     4861 attgaacacc atgcctgcaa acataatcat tgcagtagct gagccatatg ttgttaaagc
     4921 tacagctaca attgcttcat tattcggcac aacgccagat aaatgaaaag catgctcaaa
     4981 catggtacca aatggattta aagaattttg tacaattcct gcaccaccag atacaactaa
     5041 gaaaccaaca aaggtcttaa ttccaccttt aataatatca ggtaatttct tcttctgaag
     5101 aactaatcct aagattgcaa ttaaagctac taaaatagct ggtgtactaa caatatccaa
     5161 tatgaacttc atcatgacgc tagcctccta tataagtcct ttttcttcac aaagtttagt
     5221 aattaattct cgtagttcat ccatatcaat aatactattt aagatacgaa catctccaag
     5281 atgactagct gaatcagcta gatcacgacc aacaatccaa atatcagctg catttggatc
     5341 tgctccacct aaatcataat gttcaacttc tacatccgaa acattcaaat cactcaatac
     5401 agattcaata ttcatctgta ccataaaact tgaacctaat cctgaaccac aagctgtacc
     5461 aatttttaac attatctaat cctcctgttt aattatcatt ttaatgtcat catagttttt
     5521 tgatgatatt aaagtttgaa catgattttt atctcttaaa attgttgtta aatgtgacaa
     5581 agcctttaaa tgactctcat tatcaatggc tgcaatacaa atcaacaatc ttacctcttg
     5641 ttctggatta tccaataaat aaatcggttc ttccaaaact aacattgaca ttcctatttc
     5701 attcacacct tcatctggcc gagcgtgagg aattgctact cccttcccta aattaataaa
     5761 aggtccaaac tcttctactt tttgaatcat tgcctcaggg tagttctcag ttatcttatc
     5821 ttgatccaaa agcggtttag ctgctaaacg aatcgcctcc ttccatccta atttttgcga
     5881 actaacctga taggtttctt tggtaataag ttgttctagc actggtacaa tttcctttct
     5941 atcatttttt tggtaaagat aattctttaa cgccaatctt aattccaatt cttgtgtaat
     6001 aattccatat cttttgacaa tattcaggat ttgttcaatc tcaaaatctc catactctaa
     6061 attcggaaaa tcttttaaca ctagttctac tagttgtatt gcttgctctt cagtcatcat
     6121 aaccgaaact agataatttg gcttttctgt ctccaccttt atggtagaaa aaaccatatc
     6181 atagtcacta ctagctttca cctgtaaatc atcaatcttt gaggttccta taaactcaat
     6241 ttgaggaaat aatgctaata gattctcttt taacatcaat gaagaactaa caccattagg
     6301 acaaatgatt gctgctttat accatttttg aggcaaagta tctgctttct ttaaataacc
     6361 tccgaaatgg ataacaaaat atgctgtttc actatcaggt atgggattgt caatagcgtc
     6421 catcaagggc atcaaagaat ctttgactaa ttcaaataaa tcaggataat gttctttaac
     6481 atgcaataca tattcatttg aactaggtag gccgaacttt aatctatagt aagccggtat
     6541 aaggtggcgg cgaagatttt ctctcaatcc ttccctttgt ttaaaatgta acaaagaaat
     6601 atcttccatt ctacttataa tagcctctgt taattgatta aagtaaaccg gagcaacatc
     6661 tacttcacct tcaaagcaac ttgataataa aacggtgata tagcgataat catcctcaga
     6721 aaacaccgta tctataattc ccaaatcaac cactgtatcc aataaaatag tggttatatc
     6781 ttgaataaca ggagatacta atgtctctga aagacatact ctttcaacat ccctttgata
     6841 cctacacaga atgaatacta aaccgaaaag gtaaactttt aattgattaa caataggtac
     6901 tagctgtagc ttctcataat aatctttaac tacctgatca atcaaatcat aagttaatga
     6961 atacccccaa ctggataaaa cataatccaa accccaaatc cctatggagg attccagcaa
     7021 ctcactaacc atttgaaaag ctaagcggtg cttattccac tctgaaccgt gtaaagtata
     7081 accttttgct ctactgtacc ctagctccaa atcattatct aacataatct ttcttaatga
     7141 ttgaatatca gataaggttg tattcttact tactttcaaa aagtcttggt aatgactatt
     7201 cgatataaaa tctaatcggc aaaaagtgta aagatagatt aaagctaagc gagtcgactt
     7261 tggtaaaacc aattcatccg acttaataat atctgtcaaa gactgcttcg tacgatttga
     7321 taaactatag cgaccttgct ttttatccag cactatccct ttattagcta gataaggcac
     7381 taaataatct attccttctt tgacttcctt tataggtaag ctcaccttaa cagataattc
     7441 atataatgat agctcacaat gatccatcaa agtcatcaaa ataactagtg ctctataatc
     7501 aaacatttct cttcctttct aactacaatt atagtgtaaa aattataaga ataaaagagt
     7561 atttgagcac aatataatct caccttttaa aagaaattat tgggctgaaa gtttttagtg
     7621 attatttttc aactttctat tgactttata aattaaagtg atatcattta gatatcaaat
     7681 aacaggaggt cattcttatg actgaaaaac taatcaattc aaaaccaaat ggtgtattcg
     7741 cattgattct cattgagttg acaatcgtac ttggtatctt tatatttata atgggggttg
     7801 gttcggaaaa catttttgga attattatcg gacctttact aatcgtaatt gcaggtctag
     7861 ctcatgctgg tttaaaagtt gtcaaacctc aagaagctct ggttctgaca ctctttggta
     7921 actatacagg taccatcaaa gaacctggct tttactttgt caatcccttc agcgtagcag
     7981 tcaaccctgc aaaccacact cgacttggac aaagtggtga tgttagcaca aaatctcctt
     8041 ttttaggagc taaatcatca aatgacaatg atgtaaatct tgaaattggc aagaaacaga
     8101 tttccctcaa agtcatgacc ttgagcaatt ctcgtcaaaa aatcaatgat tgcttaggaa
     8161 accctgtaga aatcggtatc gcggtaactt ggagagttgt cgataccgct aaggcagtct
     8221 tcaacgttga taactacaaa gaatatcttt cattgcaatg tgatagcgcc ctccgtaata
     8281 ttgtccgcat ctatccttac gatgtgtctc ctaatgtgga tactacgggt gatgggcaag
     8341 cagatgaagg tagtctccgt ggctctagcg aaattgttgc taaccgtatt cgtgaagaaa
     8401 tccaaagtcg tgttgaggat gctggcttgg aaatccttga agcacgtatc acttacctag
     8461 cttatgctcc agaaattgct gccgttatgc ttcaacgcca acaagcatct gccattattg
     8521 atgcacggaa gatgattgta gatggtgctg taggaatggt tgaaatggca ctagaacggc
     8581 tcaatgaagg ggaattggta gaacttgacg aagaacgaaa agctgccatg gtttcaaatc
     8641 tccttgtcgt tctttgtggc aatcatgatg cacaaccaat tgtcaacaca ggaagccttt
     8701 actaaagatg gctgaagcta aaaaaaagca gatccccctt cgactctcaa caaagttata
     8761 cgctgcactc gcatcatggg cagaagacga ctttcgttca gtcaatgggc aaatcgaata
     8821 tctcctcaca gagtgtgtca agcaacggaa gaaagacgga aaatacgtat cagaaaccat
     8881 tgacgaacca tttgagattg atatttaaca ccttctcctg tctgccgtgt cggataggag
     8941 aattttttca tctttttttg tcaagtaact ttactttaca aaaaaaatgt gttatcctag
     9001 tatggttgat gaaaatcagt agattgaatc gaatataaat acctaaagga gaaatcaaaa
     9061 tggcagtacc tgcacgtcgc acttcaaaag cgaagaaaaa caaacgtcgt acacactaca
     9121 aagtaacagc tccatctgta aactttgacg aaactactgg agattactca cgttctcacc
     9181 gtgtatcact taaaggatac tacaaaggac gtaaaatcac taaagctgca tcagctgaat
     9241 aatagaaggg agataccatg cgcgtaaata ttacacttga acacaaagaa tctggtgaac
     9301 gcttgtacct tacttctaaa aacaaacgta acactccaga ccgccttcaa ttgaagaaat
     9361 actcaccaaa acttcgcaaa cacgttgtgt ttacagaggt taaataagca ttcaatacga
     9421 atcaatacag aagaaaaacg cttgatcagc gttttttctt tttgttaatt tcactacatt
     9481 gtaagggaaa tcattcgaat gactacattt ttcactacct tttttgaaat aagaatacgg
     9541 attcggacaa ttaaaagcaa gaggaactca aatgtaagtt ggggttcctt ttttgtatat
     9601 ttttcaaata acgcctctac actatttgta gcaaattcac caactacagt tgtatcttag
     9661 ttaaaataag ttagaatatg taagtgagta ccagatatac caagacatcg tcaccatcta
     9721 aggtatattc aaaatacaaa agttgaccaa ctagatttct gaatatcctt atatatccat
     9781 tcttaaaatt ggtttaaata gcgtagtctt ttaaactagt tttgagaatc caaaaaatct
     9841 tcctacatat gtaagaagat tttttagttc agaatgatta gatttagcta atggatacct
     9901 atcctaccca ctcaccgtta gcattgactc gatagccatc gggtgtagtc gtgtttacta
     9961 ataaatctcc tgaattatag gtatagtacc atttaccaga aactgtaacc caaccagtag
    10021 ccattgaacc tgattc
//
LOCUS       DAVBEO010000067         9472 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 009
            SAMEA1678075-rid20185393.denovo.067, whole genome shotgun sequence.
ACCESSION   DAVBEO010000067 DAVBEO010000000
VERSION     DAVBEO010000067.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678075
            Sequence Read Archive: ERR226392
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9472)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9472)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980207.1
            Genome Coverage       :: 150x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:50:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 72 of 147
            Pseudo Genes (incomplete)         :: 72 of 147
            Pseudo Genes (internal stop)      :: 42 of 147
            Pseudo Genes (multiple problems)  :: 32 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9472
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678075-rid20185393.denovo.067"
                     /strain="KS 009"
                     /db_xref="taxon:1313"
     gene            150..686
                     /locus_tag="VQ543_001924"
     CDS             150..686
                     /locus_tag="VQ543_001924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000709035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin transporter BioY"
                     /protein_id="HET2612593.1"
                     /translation="MKKAHVYAIPAIGAALIAALAQISLPIGPVPFTLQNFAIGLIAT
                     VFRPREAVLSAGLYLLLGAIGLPVFAGGGAGFQALVGPTAGYLWFYLVYSGLTSSLTN
                     SKSGVVKIFLANLLGDALVFVGGILSLHFLAGMAFEKALAVGVLPFIIPDLGKLLAIS
                     FISRPLLQRLKNQAYFTN"
     gene            737..823
                     /locus_tag="VQ543_001925"
                     /pseudo
     CDS             737..823
                     /locus_tag="VQ543_001925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(892..1107)
                     /locus_tag="VQ543_001926"
     CDS             complement(892..1107)
                     /locus_tag="VQ543_001926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000807422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdbC family protein"
                     /protein_id="HET2612594.1"
                     /translation="MAEFTFEIEEHLLTLSENEKGWTKEINRVSFNGAPAKFDIRAWS
                     PDHTKMGKGITLSNEEFQTMVDAFKGN"
     gene            1205..1525
                     /locus_tag="VQ543_001927"
     CDS             1205..1525
                     /locus_tag="VQ543_001927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001216095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2612595.1"
                     /translation="MRHKFQQVLNKIHDFLNGYDQPDQTETNSLTATIEEAIQKQTAV
                     HLILSETSFTGDIIKYDQQGQQIIVKNFAKNVSRIIRISDIQRLRFVPSTVQTAQKNR
                     FKKE"
     gene            complement(1556..1894)
                     /locus_tag="VQ543_001928"
     CDS             complement(1556..1894)
                     /locus_tag="VQ543_001928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001196050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2612596.1"
                     /translation="MQVIKRNGEIAEFNPDKIYQAILKAAQTVYVLTDDLRQNLAQVT
                     KKVVLDLQEAKVERATISMIQSMVEHRLLGAGYITIAEHYISYRLQRDLERSGYGDHI
                     AVHLHFEQIR"
     gene            complement(1906..2625)
                     /gene="trmD"
                     /locus_tag="VQ543_001929"
     CDS             complement(1906..2625)
                     /gene="trmD"
                     /locus_tag="VQ543_001929"
                     /EC_number="2.1.1.228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(37)-N1)-methyltransferase TrmD"
                     /protein_id="HET2612597.1"
                     /translation="MKIDILTLFPEMFSPLEHSIVGKAREKGLLDIQYHNFRENAEKA
                     RHVDDEPYGGGQGMLLRAQPIFDSFDAIEKKNPRVILLDPAGKQFDQAYAEDLAQEEE
                     LIFICGHYEGYDERIKTLVTDEISLGDYVLTGGELAAMTMIDATVRLIPEVIGKESSH
                     QDDSFSSGLLEYPQYTRPYDYRGMVVPDVLMSGHHEKIRQWRLYESLKKTYERRPDLL
                     EHYQLTVEEEKMLAEIKENKE"
     gene            complement(2615..3133)
                     /gene="rimM"
                     /locus_tag="VQ543_001930"
     CDS             complement(2615..3133)
                     /gene="rimM"
                     /locus_tag="VQ543_001930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimM"
                     /protein_id="HET2612598.1"
                     /translation="MNYFNVGKIVNTQGLQGEMRVLSVTDFAEERFKKGAELALFDEK
                     DQFVQTVTIASHRKQKNFDIIKFKDMYHINTIEKYKRYSLKVAEEDLNDLDDGEFYYH
                     EIIGLEVYEGDSLVGTIKEILQPGANDVWVVKRKGKRDLLLPYIPPVVLNVDIPNKRV
                     DVEILEGLDDED"
     gene            complement(3164..3952)
                     /locus_tag="VQ543_001931"
     CDS             complement(3164..3952)
                     /locus_tag="VQ543_001931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000819180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HET2612599.1"
                     /translation="MKRFEVSTEIGSLSVTYQKQKKVLVCLNGAGLLPSYENFSLILE
                     KPPPTIGYLTIDFPNTGRSPIHDQAGKNLDNLADAVYEVLEELGISEYILCAHSWSGI
                     LACKLLEKPIKRQTLVAIEPTTKKVMFADFSENPYPEMEEQMRLIDECGPELYFKNLT
                     QATFSPETNKKIWELMQEKGLELENQDPEFQISGEITEEDFEDVSIEAHIPVFVFCQP
                     YREKEYRESEYWTSNTKLILGGNHHYLQWSESEKIAAIIRELSE"
     gene            complement(4529..4768)
                     /locus_tag="VQ543_001932"
     CDS             complement(4529..4768)
                     /locus_tag="VQ543_001932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KH domain-containing protein"
                     /protein_id="HET2612600.1"
                     /translation="MDTIENLIIAIVKPLISQPDALTIKIEDTPEFLEYHLNLDQSDV
                     GRVIGRKGRTISAIRTIVYSVPTEYKKVRIVIDEK"
     gene            complement(4788..5060)
                     /gene="rpsP"
                     /locus_tag="VQ543_001933"
     CDS             complement(4788..5060)
                     /gene="rpsP"
                     /locus_tag="VQ543_001933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002884675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S16"
                     /protein_id="HET2612601.1"
                     /translation="MAVKIRLTRMGSKKKPFYRINVADSRSPRDGRFIETVGTYNPLV
                     AENQVTLKEDRVLAWLANGAQPSDTVRNILSKEGVLKKFHDSKFSK"
     gene            5230..5439
                     /locus_tag="VQ543_001934"
     CDS             5230..5439
                     /locus_tag="VQ543_001934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000953868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2612602.1"
                     /translation="MLSVNTILEKFYKEHQVKPFISPERELDTWLLSPKPVPKRNMDL
                     LVDDSLAGDIILLWRIQFGTFTTET"
     gene            5918..6139
                     /locus_tag="VQ543_001935"
     CDS             5918..6139
                     /locus_tag="VQ543_001935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2612603.1"
                     /translation="MSFYGLFYNGIAITPNTYLSAWFVNFIAALPLNFLIVEPIARFI
                     LSSFQKPFTGEEVEEVEDFQDDDEIPTII"
     gene            6222..7025
                     /locus_tag="VQ543_001936"
     CDS             6222..7025
                     /locus_tag="VQ543_001936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000731914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HET2612604.1"
                     /translation="MKKLATLLLLSTVALAGCSSVQRSLRGDDYVDSSLAAEESSKVA
                     AQSAKELNDALTNENANFPQLSKEVAEDEAEVILHTSQGDIRIKLFPKLAPLAVENFL
                     THAKEGYYNGITFHRVIDGFMVQTGDPKGDGTGGQSIWHDKDKTKDKGTGFKNEITPY
                     LYNIRGALAMANTGQPNTNGSQFFINQSSTDTSSKLPTSKYPQKIIEAYKEGGNPSLD
                     GKHPVFGQVIDGMDVVDKIAKAEKDEKDKPTTAITIDSIEVVKDYDFKS"
     gene            complement(7081..8622)
                     /locus_tag="VQ543_001937"
     CDS             complement(7081..8622)
                     /locus_tag="VQ543_001937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002918612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HET2612605.1"
                     /translation="MSILEVKNLSHGFGDRAIFEDVSFRLLKGEHIGLVGANGEGKST
                     FMSIVTGKMLPDEGKVEWSKYVTAGYLDQHSVLAERQSVRDVLRTAFDELFKAEARIN
                     DLYMEMAEDGADVDALMEEVGELQDRLESRDFYTLDAKIDEVARALGVMDFGMDTDVT
                     SLSGGQRTKVLLAKLLLEKPDILLLDEPTNYLDAEHIDWLKRYLQNYENAFVLISHDI
                     PFLNDVINIVYHVENQQLTRYSGDYYQFQEVYAMKKSQLEAAYERQQKEIADLKDFVA
                     RNKARVATRNMAMSRQKKLDKMDIIELQSEKPKPSFDFKPARTPGRFIFQAKNLQIGY
                     DLPLTKPLNLTFERNQKVAIIGANGIGKTTLLKSLLGIISPIAGEVERGDYLELGYFE
                     QEVEGGNRQTPLEAVWNAFPALNQAEVRAALARCGLTTKHIESQIQVLSGGEQAKVRF
                     CLLMNRENNVLVLDEPTNHLDVDAKDELKRALKEYRGSILMVCHEPDFYEGWIDQIWD
                     FNNLT"
     gene            complement(8624..9106)
                     /locus_tag="VQ543_001938"
     CDS             complement(8624..9106)
                     /locus_tag="VQ543_001938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000976721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HET2612606.1"
                     /translation="MMKKTYNHILVWGVIFYSICIVYFCFTPQEQSTVGVGTPDIQHL
                     GRLVFLLTPFNSLWKLGEVSDIGQLCWIFLQNILNVFLFFPLIFQLLYLFPNLRKTKK
                     VLLFSFLVSLGIECTQLILDFFFDFNRVFEIDDLWTNTLGGYLAWLLYKRLHKNKIRN
                     "
     gene            complement(9106..>9472)
                     /locus_tag="VQ543_001939"
     CDS             complement(9106..>9472)
                     /locus_tag="VQ543_001939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="50S rRNA methyltransferase"
                     /protein_id="HET2612607.1"
                     /translation="KLFAAIEYYIETTNRRVTFEYIMLNEVNDGVEQALELAELLKNI
                     KKSSYVNLIPYNPVSEHDQYSRSPKERVLAFYDTLKKKGGNCVVRQEHGTDIDAACGQ
                     LLFNTMKRDRQKAVAAVNP"
BASE COUNT         2796 a         2028 c         1698 g         2950 t
ORIGIN      
        1 attttcgaat caacaaaaaa attatccaac ttgactagtc acgaaaatcg gctgttacag
       61 tttttgttac cttgttttta aaaaatggtt gacatcgact cctatatgag tataatagtt
      121 atcatacatt agaaaagagg ttaactattt tgaaaaaagc tcacgtttat gctatccctg
      181 ctattggggc tgctctcatt gctgctttgg cacaaatcag tcttccaatt ggacctgttc
      241 ccttcactct gcaaaacttt gcaatcggct tgattgctac tgtctttaga ccgagagagg
      301 ctgtactttc tgctggactc tatcttcttc taggtgctat cggtcttcct gtctttgcag
      361 gaggtggagc tggttttcag gctttagttg gccctactgc aggctatctt tggttttatc
      421 tcgtttactc tggacttact tcctctctaa ccaacagcaa gagtggtgtt gttaagattt
      481 ttcttgcaaa cctcttgggt gatgcccttg tctttgtcgg cgggattctc agcttgcatt
      541 tcctagctgg aatggcattt gaaaaagctc ttgctgtggg ggttcttccc tttatcattc
      601 cagaccttgg caaacttctg gctattagtt ttattagccg tcccctactt caacgcctta
      661 aaaatcaggc ttactttact aactaaaaaa ggatatcgag ttatcatgac tcaatatcct
      721 tttcttttat tttgaaaact tatactcaat gaaaatcaaa gagcaaacta gaaagctagc
      781 cgcaggctgc tcaaaacact gttttgaggt tgtggatgaa actgacgaag tcagtaacca
      841 tacatacggc aaggcaaagc tgacgcggtt tgaagagatt ttcgaagagt attagttgcc
      901 tttaaaggca tccaccatcg tttgaaattc ttcatttgag agagtaatcc ctttgcccat
      961 tttagtatgg tctggactcc aagcacgaat atcaaacttt gcaggggcac cattaaagct
     1021 cacacggtta atttccttgg tccaaccttt ttcgttttca gaaagagtca acaagtgctc
     1081 ttcgatttca aatgtaaatt ctgccatttt cttctccttt tttagtttca ttagtttatt
     1141 cgtaaaatct tgtagatttt aggaaaattt tatataatat tgatataaaa gaagggaggc
     1201 caatatgaga cataaattcc agcaagttct aaataaaata catgattttt taaatggata
     1261 tgaccaacct gaccagactg aaaccaactc ccttacagcc actattgaag aggctatcca
     1321 gaaacaaacc gctgttcacc ttatcttgtc tgagacaagt tttacaggtg atatcatcaa
     1381 atatgatcag caaggccagc aaattatcgt gaaaaatttt gccaaaaatg tgagccggat
     1441 tatccgtata agcgatattc aacgcctgcg atttgtcccc tcaactgtcc aaacagccca
     1501 aaaaaataga tttaagaaag agtgagatgt agttgcttca tcccactctt ttttcttagc
     1561 gaatttgttc aaaatgtaaa tgaactgcaa tatgatctcc ataaccactt ctttccaagt
     1621 cacgttgtaa acgataggaa atgtagtgtt ctgcaatggt aatgtaacct gcgcccaata
     1681 aacgatgttc aaccatagat tgaatcatac tgatagtcgc acgttccacc ttggcttctt
     1741 gtaaatccaa aactaccttc ttagtgactt gagcaagatt ttgacgcaaa tcatctgtca
     1801 aaacataaac agtttgggct gccttcaaga tggcttggta aatcttatct ggattaaatt
     1861 cagcaatttc gccattacgt ttgattactt gcataggttt ctcctttatt ctttgttttc
     1921 tttgatttct gccagcattt tttcttcttc tactgtcagt tgataatgtt caagtaaatc
     1981 cggtctgcgc tcgtaggttt tctttaaact ctcgtacaat cgccactgac gaatcttttc
     2041 atggtggcca ctcatcaata catctggcac gaccatgcct cgataatcat agggacgtgt
     2101 gtactgagga tattctaaaa gacctgaaga aaaactatca tcttggtggc tagactcctt
     2161 gccaatcact tctggaatca ggcgaactgt agcatcaatc atggtcatag ctgccaattc
     2221 tccaccagtg aggacatagt cgcctaggga aatctcatct gttaccaagg tcttaatgcg
     2281 ctcatcataa ccctcatagt gcccacagat aaagattagc tcttcctctt gagccaaatc
     2341 ttcagcataa gcctgatcaa actgctttcc agcaggatcg aggagaataa cgcgcggatt
     2401 tttcttttca atagcatcaa aggaatcgaa aataggttgt gctctgagca acatgccctg
     2461 accgcctccg tagggctcat catctacatg acgggccttt tcagcatttt ctcgaaaatt
     2521 atgatactgg atatccaaga gccctttttc tcgagccttt ccaacgattg agtgctccag
     2581 tggagaaaac atctctggaa agagggttaa aatatcaatc ttcatcgtct aacccttcta
     2641 agatttccac atcgacccgt ttatttggaa tatcaacatt gagaaccact ggtgggatat
     2701 aaggtaaaag caaatcacgt ttgccttttc gtttgaccac ccagacatca ttagcacctg
     2761 gttgcaggat ttccttgatg gttccaacca agctatcacc ctcatagact tccaaaccga
     2821 taatctcgtg atagtaaaat tcaccatcgt ctaggtcatt caaatcttcc tcagcgacct
     2881 tgagactata tctcttgtac ttttcgatag tattgatatg gtacatatct ttgaatttaa
     2941 taatgtcaaa gttcttctgt ttacggtggc tagcgatggt cactgtttgg acaaactgat
     3001 ctttttcatc aaacaaagcc agctcagctc cttttttaaa ccgttcttct gcaaaatccg
     3061 tcacagacaa gactcgcatc tcaccctgta atccctgcgt attaacgatt ttcccaacat
     3121 taaagtagtt catcttgtct cctgtaatct ccttttttcc atcttattct gacaattctc
     3181 gaataatagc cgcaattttt tccgattctg accattgtaa ataatggtga ttccctccta
     3241 aaatgagttt agtattggaa gtccaatatt ctgattctct gtactctttt tctctataag
     3301 gctgacaaaa aacaaataca ggaatatgag cttctataga tacatcctca aaatcttcct
     3361 cagtaatctc tccagatatc tgaaattctg gatcttgatt ttccaactct aagccttttt
     3421 cttgcattaa ttcccagatt tttttattcg tttcaggact aaatgttgct tgagttaagt
     3481 tcttaaaata aagttcagga ccacactcgt caatcagcct catctgctct tccatttctg
     3541 gataaggatt ttctgaaaaa tcagcaaaca tgactttttt agttgtcggt tcaattgcta
     3601 ctaaagtctg acgcttaatt ggtttctcga gtaatttgca agctaaaatt ccactccaac
     3661 tatgtgcaca aagtatatat tcagaaattc ctaattcttc aagtacttca taaaccgcat
     3721 ctgcaagatt atctagattt tttccagctt ggtcatgaat cggactccta cctgtgttcg
     3781 gaaaatcaat tgtcaaataa ccaattgtag gaggaggttt ttcaagtata agtgaaaaat
     3841 tttcataact tggtagcaaa cctgctccgt ttagacaaac tagcactttc ttttgctttt
     3901 gataagtaac agagaggcta ccaatttctg tagatacttc aaacctcttc ataaagaaat
     3961 ccactcattc tatataatga attattaaaa atccttatct tttattttat cacgttccaa
     4021 ggattttctc aagttggagg aaggggacaa catctctact ttcccttcaa aaatccttcc
     4081 aaatcatgtt tatgttggta attaacggct gcggttttgt ctttctcaaa gacagtcttg
     4141 gtaaggtcaa tatgattaat agctacgatt gcgacggtgt agtaaatgat atcagccagt
     4201 tctctggcaa gttcctcgtt cgaatcctat cccttctttt cgaccagagc gcctattcaa
     4261 aacctcggct acttctccga cttcctccac taacttcata aagagacctt catcagtccg
     4321 agactgctgt taatgttcga ttaagtagtc ttggaattgc ctaaacgttc aatcttttat
     4381 agtatattga aactagaata gtacaccttt acttctaaaa cattgttaga aatcgatttg
     4441 actgtcctga tcgatttgtc ctgttcttgt ttcattttac tatatcttct attccacaca
     4501 aaaaagcgag acatccgtcc cgcccttctt atttttcgtc aataacgatt cttacttttt
     4561 tgtattcagt tgggacagag tagacaatcg ttcttatcgc agaaatagtg cgacccttac
     4621 gaccgattac acgacccaca tcgctttgat caagattcaa atgatattcc aaaaattctg
     4681 gtgtatcctc aatcttgata gttaaggcat ctggttgtga aattaagggt ttcacaatcg
     4741 caataatgag attttcaatc gtatccatct gtcaacctac tttaaactta ttttgaaaat
     4801 ttagaatcgt ggaatttttt caatacgcct tcttttgaaa ggatgttacg tactgtgtct
     4861 gaaggttgag ctccattagc caaccatgca agaacgcggt cttctttcaa agttacttgg
     4921 ttttcagcaa caagtgggtt gtaagttcca actgtttcga tgaaacgtcc gtcacgtggt
     4981 gaacgtgaat ctgctacgtt gatacggtag aaaggttttt tcttagaacc catacgagtc
     5041 aaacggattt taactgccat ttttaaagtc tcatttcttt aattttttat ttcggtgaaa
     5101 tagctgagct atttagcaca tgttctatta tagcagattt ctggcatgtg tcaagaaaaa
     5161 aacttgacag actataaatt tcttaaagta tttagaaatt tgttagaata ggaaataaat
     5221 gtttgaaaga tgctatccgt gaatactatt ttagaaaaat tttataaaga acaccaagtc
     5281 aaacccttca tatcgcctga acgagagttg gatacttggc ttctaagtcc caagcccgtt
     5341 cccaagcgaa atatggactt attagtagat gattcactag caggagatat cattttacta
     5401 tggagaatcc agtttggtac ttttaccact gaaacatgat tttaaaaact cccattcgaa
     5461 tatgattcaa aattcgctta gaatcaatgt tttcccgctt tttcaaaaaa taaattttca
     5521 tctaatttaa ataactttca attaagtgtg aattttgctt aaaatcatta aaaagcaccc
     5581 catggtgtga accatgaagt gttgtaaatg ctgtgttgta gctagttctt agcgtttaga
     5641 gaactggcta gctttacgag ctttcttaag atctggtttc caaaatactt tgagtacact
     5701 tatggtattg atgcccctaa acatctaaaa actctggtag aaaaagggta tgctcttgtc
     5761 gaaacttctt ttgactcact tgaccatcta aataatacca tgaaaaagaa tatcctgaag
     5821 aagaagggag ttactggact ttctaaaatg aaatcttgcg acctggatca agcccttcat
     5881 gagcattttt cagaagaaga attagctggt cactttcatg tccttctatg gactttttta
     5941 caatggcatt gctatcacac ccaataccta tctaagcgcc tggttcgtaa actttattgc
     6001 agctcttcct ctaaatttcc taattgttga accaattgcc cgttttatac taagttcttt
     6061 tcagaaacca tttactgggg aagaagttga agaagttgaa gattttcaag atgatgatga
     6121 aatcccaact attatctaag ccagttctgt aaactactaa tatttgaaat ccacttcttt
     6181 ttagggtaca atggtataaa tgaatttttg agaggatcag aatgaaaaaa ctagcaaccc
     6241 ttcttttact gtctactgta gccctagctg ggtgtagcag cgtccaacgc agtctgcgtg
     6301 gtgatgatta tgttgattcc agtcttgctg ctgaagaaag ttccaaagta gctgcccaat
     6361 ctgccaagga gttaaacgat gctttaacaa acgaaaacgc caatttccca caactatcta
     6421 aggaagttgc tgaagatgaa gccgaagtga ttctccacac aagccaaggt gatattcgca
     6481 ttaaactctt ccctaaactc gctcctctag cggttgaaaa tttcctcact cacgccaaag
     6541 aaggctacta taacggtatt accttccacc gtgtcatcga tggctttatg gtccaaactg
     6601 gagatccaaa aggggacggt acaggtggtc agtccatctg gcatgacaag gataagacta
     6661 aagacaaagg aactggtttc aagaacgaga ttactcctta tttgtataac atccgtggtg
     6721 ctcttgctat ggctaatact ggtcaaccaa acaccaatgg cagccagttc ttcatcaacc
     6781 aaagctctac agatacctct tctaaactcc ctacaagcaa gtatccacag aaaattatcg
     6841 aagcctacaa agaaggtgga aaccctagtc tagatggcaa acacccagtc tttggtcaag
     6901 tgattgacgg tatggatgtt gtggataaga ttgctaaggc cgaaaaagat gaaaaagaca
     6961 agccaactac tgctatcaca atcgacagca tcgaagtggt gaaagactac gattttaaat
     7021 cttaaaaacc aaaaaaatac agtatccaca ttcggtactg tatttctttt actctcattc
     7081 ttaagttaaa ttattaaaat cccatatttg gtctatccag ccttcataaa agtctggctc
     7141 gtggcagacc ataaggatag atcccctata ttctttgaga gcgcgtttga gctcatcctt
     7201 tgcatccaca tccaaatggt tggtcggctc gtccagcact aaaacgttgt tttcacgatt
     7261 catcaagaga cagaaacgaa ccttggcttg ctctccccct gataatactt gaatctggct
     7321 ttcaatatgt ttggttgtca aaccacaacg ggcaagggct gcacggactt ctgcttgatt
     7381 aagggcagga aaggcattcc agacagcttc aagaggagtt tggcgattac cgccttctac
     7441 ttcctgctca aaataaccaa gttctaaata atctccacgc tccacttccc cagcgattgg
     7501 cgagataatg cccaagagac tcttcaagag agttgttttt ccaataccat tagcaccaat
     7561 aatcgcaacc ttttgattgc gttcgaaggt aagatttaaa ggcttagtaa gaggaaggtc
     7621 gtaaccaatt tgcaagttct tggcttggaa gataaagcgc cctggtgtac gagctggttt
     7681 gaaatcaaag gatggttttg gtttctcact ttggagttcg ataatatcca tcttatccaa
     7741 tttcttttga cgagacatag ccatattacg agttgcaaca cgggctttat tacgagccac
     7801 aaagtccttg aggtctgcaa tctctttctg ctggcgttcg taggctgcct ctagctgaga
     7861 tttcttcata gcataaactt cttggaactg gtagtagtca ccagagtaac gcgtcagctg
     7921 ttgattttcc acatgataga caatattgat aacgtcattg aggaatggaa tatcgtgcga
     7981 aatgagaaca aaggcattct catagttttg gagatagcgc ttgagccaat caatatgctc
     8041 agcatccaag tagttggtcg gctcgtccaa cagcaagata tcaggctttt caaggagaag
     8101 ttttgccaaa agcaccttgg ttctttgccc acctgacaaa gaagttacat ccgtatccat
     8161 gccaaagtcc ataacaccaa gagcacgcgc tacttcgtca atcttagcat ccaaggtata
     8221 gaaatcacga ctctccagac ggtcttgaag ttctcctact tcttccatga gagcatcaac
     8281 atccgcaccg tcttcagcca tttccatata gaggtcattg atacgagctt cagctttgaa
     8341 aagctcatca aaagccgtac ggagaacatc acgcaccgac tgtctttcag caaggacaga
     8401 gtgctgatcc aagtaaccag ccgtcacata tttggaccac tcaacctttc cttcatctgg
     8461 cagcatttta ccagtcacga tactcataaa ggttgatttt ccttcaccat tggcaccgac
     8521 caggccgata tgttctccct tgaggagacg gaaggacaca tcttcaaaaa ttgcacggtc
     8581 accaaaaccg tgactcagat ttttaacttc taaaatactc attttaattc cttatcttgt
     8641 ttttatgtaa tcgtttataa aggagccaag ccagatagcc acccaaagtg ttggtccaca
     8701 aatcatcaat ctcaaagacg cgattgaaat caaagaaaaa gtccaagatt aattgcgtac
     8761 actcgattcc aagactcaca agaaaactaa aaagaaggac cttttttgtt ttccgcaaat
     8821 ttggaaatag ataaaggagt tggaaaatca gaggaaaaaa caagaagaca ttgaggatat
     8881 tttgtaaaaa aatccaacat aattgtccaa tgtcactcac ttcgcccagt ttccagagag
     8941 aattgaaagg agtcaaaaga aaaaccaggc gtccaagatg ctgaatatct ggagttccca
     9001 ctcccacggt agattgttct tgaggagtaa agcaaaaata gacaatgcaa atgctataga
     9061 aaatgactcc ccagaccaaa atatgattat aagtcttctt catcattaag gatttaccgc
     9121 tgcgactgcc ttctggcggt cacgtttcat tgtgttaaag agcaattgtc cacaagctgc
     9181 gtcaatatct gtaccatgct cttgacgaac cacacagttg cccccttttt tcttaagcgt
     9241 atcatagaaa gccaacacgc gctctttggg actacggcta tattggtcat gctcactaac
     9301 tgggttataa ggaatcaagt ttacataaga cgatttcttg atgttcttga gcaattcagc
     9361 caattccaag gcttgttcca caccgtcgtt gacttcatta agcatgatat attcaaaggt
     9421 tacacgacgg tttgttgtct caatgtagta ttcaatagca gcaaagagtt tt
//
LOCUS       DAVBEO010000068         9181 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 009
            SAMEA1678075-rid20185393.denovo.068, whole genome shotgun sequence.
ACCESSION   DAVBEO010000068 DAVBEO010000000
VERSION     DAVBEO010000068.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678075
            Sequence Read Archive: ERR226392
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9181)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9181)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980207.1
            Genome Coverage       :: 150x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:50:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 72 of 147
            Pseudo Genes (incomplete)         :: 72 of 147
            Pseudo Genes (internal stop)      :: 42 of 147
            Pseudo Genes (multiple problems)  :: 32 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9181
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678075-rid20185393.denovo.068"
                     /strain="KS 009"
                     /db_xref="taxon:1313"
     gene            complement(135..1103)
                     /locus_tag="VQ543_001940"
     CDS             complement(135..1103)
                     /locus_tag="VQ543_001940"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006149122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HET2612608.1"
                     /translation="MSFSDLKLFALSSNKELAERVAQEIGIELGKSSVRQFSDGEIQV
                     NIEESIRGKHVFILQSTSSPVNDNLLEILIMVDALKRASAESVNVVMPYYGYARQDRK
                     ARAREPITSKLVANMLEVAGVDRLLTIDLHAAQIQGFFDIPVDHLMGAPLIADYFERR
                     GMVGSDYVVVSPDHGGVTRARKLAEFLKTSIAIIDKRRSVDKMNTSEVMNIIGKVEGK
                     TCILIDDMIDTAGTICHAADALAEAGAVEVYASCTHPVLSGPATDNIQKSAIKKLVVL
                     DTIYLPEERLIDKIEQISIAHLLGDAIVRIHEKRPLSPLFDIEKKI"
     gene            complement(1248..2063)
                     /locus_tag="VQ543_001941"
     CDS             complement(1248..2063)
                     /locus_tag="VQ543_001941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000749763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PrsW family intramembrane metalloprotease"
                     /protein_id="HET2612609.1"
                     /translation="MKKSSILFIFILLLCIGLQYETIYYTDGSRSGAEYGLMGVSIFL
                     ALFYMIPALYFLFRIGKKWELPKKVLILSLLGGMFLSGWLSSFTNTYIHDLLGVLFPD
                     SPFLNAFESAIVAPLVEEPLKLLPLVFVLALIPVRKLKSLFLLGIASGLGFQMIEDIG
                     YIRTDLPEGFDFTISRILERIISGIASHWTFSGLAVVGVYLLYRAHKEQKVGKKQGLI
                     FLGLALRTHFLFNSPFVELETELPLAIPVVTAIALYGFYHAYCFVEKHNELMT"
     gene            complement(2088..2585)
                     /locus_tag="VQ543_001942"
     CDS             complement(2088..2585)
                     /locus_tag="VQ543_001942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbonic anhydrase"
                     /protein_id="HET2612610.1"
                     /translation="MSYFEQFMQANQAYVALHGQLNLPLKPKTRVAIVTCMDSRLHVA
                     QALGLALGDAHILRNAGGRVTEDMIRSLVISQQQMGTREIVVLHHTDCGAQTFENEPF
                     QEYLKEELGVDVSDQDFLPFQDIEESVREDMQLLIESPLIPDDVIISGAIYNVDTGSM
                     TVVEL"
     gene            complement(2658..4019)
                     /gene="radA"
                     /locus_tag="VQ543_001943"
     CDS             complement(2658..4019)
                     /gene="radA"
                     /locus_tag="VQ543_001943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000336571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadA"
                     /protein_id="HET2612611.1"
                     /translation="MAKKKATFVCQNCGYNSPKYLGRCPNCGSWSSFVEEVEVAEVKN
                     ARVSLTGEKTKPMKLAEVTSINVNRTKTEMEEFNRVLGGGVVPGSLVLIGGDPGIGKS
                     TLLLQVSTQLSQVGTVLYVSGEESAQQIKLRAERLGDIDSEFYLYAETNMQSVRAEVE
                     RIQPDFLIIDSIQTIMSPEISGVQGSVSQVREVTAELMQLAKTNNIAIFIVGHVTKEG
                     TLAGPRMLEHMVDTVLYFEGERHHTFRILRAVKNRFGSTNEIGIFEMQSGGLVEVLNP
                     SQVFLEERLDGATGSSIVVTMEGTRPILAEVQALVTPTMFGNAKRTTTGLDFNRASLI
                     MSVLEKRAGLLLQNQDAYLKSAGGVKLDEPAIDLAVAVAIASSYKDKPTNPQECFVGE
                     LGLTGEIRRVNRIEQRINEAAKLGFTKIYVPKNSLTGITLPKEIQVIGVTTIQEVLKK
                     VFA"
     gene            complement(4033..4548)
                     /locus_tag="VQ543_001944"
     CDS             complement(4033..4548)
                     /locus_tag="VQ543_001944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HET2612612.1"
                     /translation="MKIIFVRHGEPDYRELEERSYIGFGIDLAPLSEMGRQQVQKLSK
                     NPLLSSAEIIVSSAVTRALETASYVVCATGFPLRVEPLLHEWQVYKTGIENFETARRL
                     FLENKGELLPNSPIQYETATEMKSRFLECMSKYREHQTVVVVAHRMLMRQFVPNEKID
                     FCQVIECELEI"
     gene            complement(4550..4993)
                     /locus_tag="VQ543_001945"
     CDS             complement(4550..4993)
                     /locus_tag="VQ543_001945"
                     /EC_number="3.6.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dUTP diphosphatase"
                     /protein_id="HET2612613.1"
                     /translation="MKIRGFELVSSFTDENLLPKRETAHAAGYDLKVAVRTVVAPGEI
                     VLVPTGVKAYMQPTEVLYLYDRSSNPRKKGLVLINSVGVIDGDYYGNPGNEGHIFAQM
                     KNITDQEVVLEVGERIVQAVFATFLIADGDAADGVRTGGFGSTGH"
     gene            complement(5050..5147)
                     /gene="ffs"
                     /locus_tag="VQ543_001946"
     ncRNA           complement(5050..5147)
                     /ncRNA_class="SRP_RNA"
                     /gene="ffs"
                     /locus_tag="VQ543_001946"
                     /product="signal recognition particle sRNA small type"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00169"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00169"
     gene            complement(5180..5647)
                     /locus_tag="VQ543_001947"
     CDS             complement(5180..5647)
                     /locus_tag="VQ543_001947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside deaminase"
                     /protein_id="HET2612614.1"
                     /translation="MYYTLEEKEVFMREALREAEIALEHDEIPIGCVIVKDGEIIGRG
                     HNAREELQRAVMHAEIMAIEDANLSEESWRLLDCTLFVTIEPCVMCSGAIGLARIPNV
                     VYGAKNQKFGAAGSLYDILTDERLNHRVEVEIGILEDECAAIMQDFFRNRRKK"
     gene            complement(5848..7134)
                     /locus_tag="VQ543_001948"
     CDS             complement(5848..7134)
                     /locus_tag="VQ543_001948"
                     /EC_number="6.3.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate synthase"
                     /protein_id="HET2612615.1"
                     /translation="MTSVVVVGTQWGDEGKGKITDFLSANAEVIARYQGGDNAGHTIV
                     IDGKKFKLHLIPSGIFFPEKISVIGNGMVVNPKSLVKELSYLHEEGVTTDNLRISDRA
                     HVILPYHIELDRLQEEAKGDNKIGTTIKGIGPAYMDKAARVGIRIADLLDKDIFRERL
                     ERNLAEKNRLFEKLYDSKAIVFDDIFEEYYEYGQQIKKYVIDTSVILNDALDNGKRVL
                     FEGAQGVMLDIDQGTYPFVTSSNPVAGGVTIGSGIGPSKIDKVVGVCKAYTSRVGDGP
                     FPTELFDEVGERIREVGHEYGTTTGRPRRVGWFDSVVMRHSRRVSGITNLSLNSIDVL
                     SGLDTVKICVAYDLDGQRIDYYPASLEQLKRCKPIYEELPGWSEDITGARNLEDLPEN
                     ARNYVRRVSELVGVRISTFSVGPGREQTNILESVWS"
     gene            complement(7365..7601)
                     /locus_tag="VQ543_001949"
     CDS             complement(7365..7601)
                     /locus_tag="VQ543_001949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecX"
                     /protein_id="HET2612616.1"
                     /translation="MLQKIYEQMTNFYDSIEEEYGPTFGDNFDWEHVHFKFLIYYLVR
                     YGIGCRRDFIVYHYRVAYRLYLEKLVMNRGFISC"
     gene            7867..8664
                     /locus_tag="VQ543_001950"
                     /pseudo
     CDS             7867..8664
                     /locus_tag="VQ543_001950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436304.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(8699..9181)
                     /locus_tag="VQ543_001951"
                     /pseudo
     CDS             complement(8699..9181)
                     /locus_tag="VQ543_001951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="internal stop; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         2944 a         2179 c         1473 g         2585 t
ORIGIN      
        1 tgatgacgta cagtcatatt tcttctcttt ttattatatc acagttttaa atctagcttt
       61 actagattca ccgctactat ctatttattc ggaaaaaaga cgaaaaaacc tgagaatcat
      121 ctcaggcttg gtcattaaat ttttttctca atatcgaaaa gtggagaaag tggtcgtttt
      181 tcatgaatac gtacgatagc atcccctagg agatgagcga ttgaaatctg ctcaatctta
      241 tcaatcaaac gctcttctgg cagatagatg gtatccaaaa caaccaattt cttaatagct
      301 gatttttgga tattgtccgt agcaggacca gaaagaactg ggtgcgtaca gcttgcatag
      361 acttcaacag caccagcttc cgcaagagca tctgccgcat gacaaatcgt tccagcggta
      421 tcaatcatat catcaatcaa gatacaagtc ttgccttcaa ccttaccgat gatgttcata
      481 acttcactag tattcatctt atcaacgcta cgacgtttat caataatagc gatagatgtt
      541 ttcaaaaatt ctgccaactt acgagcacga gtcacccctc catggtccgg gctgacaacc
      601 acatagtcag aaccaaccat accacgacgc tcaaaataat ctgcaatcag aggagcaccc
      661 atcaaatgat ccacaggaat atcaaagaat ccttgaattt gcgcagcatg caagtcgatg
      721 gtcaataaac gatccactcc agctacttca agcatatttg cgacaagttt tgaagtgatt
      781 ggctcacgcg ctctcgcctt tctatcctga cgtgcatacc catagtaagg catgacaaca
      841 ttgacagatt ctgcactcgc acgcttcaaa gcatctacca taatcaaaat ttcaagcaga
      901 ttgtcattta caggcgaact agttgattgt aggataaaga cgtgtttccc acggattgat
      961 tcttcaatgt tgacctgaat ctctccatct gaaaattggc gaacacttga tttccccaac
     1021 tctatcccaa tctcctgcgc cacacgttct gccaattctt tattagaaga aagggcaaac
     1081 agctttaaat cagaaaaaga catgatttcc tccggtatat atgtatcgct tgtgcttttc
     1141 acaagatttt ccatctacca ttgtagcgct ttttgcacta tttttcaatc aaaaataaaa
     1201 gaagggcacc atatttgtac ccttgcatca ttcttttgaa aaatattcta ggtcatcaac
     1261 tcattgtgtt tctcaacaaa gcaataagca tgataaaaac catagagagc aatagccgta
     1321 accactggaa tcgctaaagg caactctgtt tccaactcca caaaaggaga gttaaacaag
     1381 aagtgagttc tcaaggctaa acctagaaaa ataaggccct gtttcttgcc aaccttctgt
     1441 tctttatggg ctctgtaaag caagtaaaca cctactacag ctagacctga aaaagtccag
     1501 tgagaggcaa ttcctgagat gatacgctct aaaattcgcg aaatagtaaa gtcaaagccc
     1561 tctggcaaat ccgtacgaat ataaccaata tcctcaatca tttggaatcc caaaccggaa
     1621 gcaattccaa gtaaaaacaa agattttaat tttcgcacag gaatcaaagc caaaacaaaa
     1681 acaagtggca ataatttcaa gggttcttct accaaaggag ccacaatagc actttcaaag
     1741 gcatttaaaa atggactatc tgggaaaaga acccccagta aatcatggat ataagtatta
     1801 gtaaaactag acaaccagcc tgaaaggaac atccctccca ataaagacag aatcaaaacc
     1861 ttctttggca attcccattt tttcccaata cggaagagaa aataaagagc cggaatcatg
     1921 taaaagagag ctagaaagat agaaactccc attagtccat attccgcacc tgacctcgaa
     1981 ccgtccgtat agtagatggt ttcatactgt aaaccaatac atagcaataa aataaaaata
     2041 aataaaatac tgcttttctt catacacttt ctttctaaat gaagtattta taattctacg
     2101 actgtcatac ttcctgtatc aacattgtaa atggcaccag agataatgac atcgtctggt
     2161 attaggggag actcgataag cagttgcata tcctcgcgta cactctcttc tatatcttgg
     2221 aagggcaaga agtcctggtc tgacacatct acacctaatt cctcttttaa atactcctga
     2281 aaaggttcat tttcaaaggt ctgagcacca cagtctgtat ggtgcaatac cacaatctct
     2341 cttgtcccca tttgttgctg ggaaataact agcgaacgaa tcatgtcttc agtcactcga
     2401 ccacctgcat tccgcaagat atgagcatcc ccaagtgcca agcccagagc ttgcgcaacg
     2461 tgcagacgag agtccataca ggtcacaata gctactcttg ttttgggttt aagtggcaga
     2521 tttaactgcc catgtagggc aacataagcc tgattagctt gcataaactg ttcaaaatac
     2581 gacacgattc cctccttgaa aatttgatag tcaaatattt ctcctatctt atcattttta
     2641 agagaatttg tcacggatta tgcaaagacc tttttcaaaa cttcctgaat cgttgtcacg
     2701 ccaatgacct gaatttcctt aggcagagtg attcctgtca aggaattctt aggtacataa
     2761 atcttagtaa agcccagttt agcagcttcg ttgatgcgtt gctcaatacg attcacgcgc
     2821 cgaatctctc ctgtcaagcc cagttctccg acaaaacatt cctgaggatt agttggcttg
     2881 tctttgtagc tcgaagcaat agcaactgca acagccaagt caatggcagg ttcatccaat
     2941 ttaacaccac cagcagattt gagataggca tcctgatttt gcaagagaag ccctgcccgt
     3001 ttttccaaaa cagacataat caagctagca cggttaaaat caagtcctgt cgtagtacgc
     3061 ttggcatttc caaacatggt cggtgttacc aaagcctgaa cctccgccaa aatcggacgc
     3121 gtcccttcca tggttacaac gatggaggaa ccagtcgccc catccaaacg ctcttctagg
     3181 aaaacttgac tcggattgag tacctcaacc aagccgcccg actgcatctc aaaaatccca
     3241 atctcattag tggaaccaaa acgatttttg accgctctca aaatacgaaa ggtgtggtga
     3301 cgctcccctt caaagtaaag caccgtatcc accatatgct ccaacatacg aggcccagcc
     3361 aaggttcctt ctttggtcac atgacctacg ataaagatgg caatgttatt ggtcttggcc
     3421 aactgcatga gttcagcggt cacttcacgc acctgagaaa cagacccctg cacccctgaa
     3481 atctcaggag acatgatggt ctggatggaa tcaataatga gaaagtctgg ctggatacgc
     3541 tccacttctg cacgaacact ctgcatattg gtctctgcat agagataaaa ctcactatca
     3601 atatcaccta agcgctctgc acgtagttta atctgctggg cagactcctc cccactgaca
     3661 tagagaactg tccccacttg ggacaactgg gttgagactt gtaggagaag agttgatttc
     3721 ccaatcccag gatccccacc gatgaggacg agacttcctg gtaccactcc gcctccaagc
     3781 acacggttga attcctccat ctccgtcttg gttcgattga cattgatgga agtcacctca
     3841 gctagtttca tgggcttggt tttctcacct gtcaaggaca cacgcgcatt cttgacctcg
     3901 gcaacctcaa cctcttccac aaaagaagac caagacccac agttggggca acgtcccaga
     3961 tatttagggg aattataccc acaattttga catacaaatg tcgctttttt ctttgcgatg
     4021 acaaacctct ttctatatct ctaactcaca ctcaatcact tggcaaaaat caatcttctc
     4081 atttggcaca aactggcgca tgagcattcg atgagcaaca actaccacag tctgatgttc
     4141 tcgatactta gacatacatt ctagaaaccg agacttcatt tccgtagctg tctcatattg
     4201 aataggacta ttaggaagca actccccctt gttttctaaa aacagtcttc tagctgtttc
     4261 aaagttttct attcctgttt tatagacctg ccattcatgt aataaaggct ctactcttaa
     4321 aggaaaaccc gtagcacata ccacatacga agccgtttct aaagctcttg tgactgcaga
     4381 agatacgatt atttcagctg acgagagtaa aggatttttg ctcaatttct ggacttgctg
     4441 ccgtcccatc tcagacaagg gtgccaaatc tatcccaaat cctatataag aacgctcctc
     4501 taactcacgg taatctggct ccccatgacg tacaaagata atcttcattc tagtgccctg
     4561 tcgatccaaa tccaccagtt cgaacgccat cagccgcatc tccatctgca attaagaaag
     4621 tagcaaaaac agcctggaca atacgctccc caacttcaag aacaacctct tggtctgtga
     4681 tattcttcat ctgcgcaaaa atatgccctt catttccagg atttccataa taatccccat
     4741 caatgactcc aactgagtta attaaaacca agcccttctt acgaggattt gaagaacgat
     4801 catagaggta gagaacctca gtcggctgca tataagcctt aacccctgtc ggaaccaaga
     4861 caatctctcc tggcgcaaca actgtacgca cagcaacctt taagtcgtaa ccagccgcat
     4921 gcgctgtctc acgcttgggc aataaatttt catctgtaaa actcgaaacc aattcaaaac
     4981 cacgaatttt cataattttc tcttttctat tatcatttat tctagattat tctatcttat
     5041 ttattcggaa aaagcacgaa aaaaagagca cacaattcaa atcgcttagg gctgctggat
     5101 tcctcccctg acccgcttca cgcagaactg ttgctccact atttattata tcacattcct
     5161 attcatttta aaagcaaaat tattttttcc gtctatttct aaaaaaatcc tgcatgatag
     5221 ctgcgcattc atcttccaaa attcctattt caacctccac acgatgatta agacgctcat
     5281 ctgtcaagat atcgtacaaa cttccagcag cgccaaattt ctggttttta gccccataga
     5341 ccacatttgg aatgcgggca agcccaatcg ccccactaca catgacacaa ggttcaatgg
     5401 tcacaaaaag tgtgcaatcc agcaagcgcc agctctcctc actcaagttc gcatcctcta
     5461 tagccataat ttccgcatgc ataaccgctc gctgtaattc ctcacgcgca ttatgcccac
     5521 gaccaatgat ttccccatct ttgacaatca cacaaccaat tggaatttca tcgtgttcaa
     5581 gagcaatctc agcctctctc aaagcctccc tcataaagac ttctttttct tcaagcgtat
     5641 aatacatctc ttttctcttt tcctacttat cgattttatt attatatcat gaatcccaac
     5701 acaaaaaaag ccaccgaatg cggtgactct atagggagat tattatgaaa aagaaaagtt
     5761 taggatattt gttacaacaa gttaggaggt cttcttgtaa ctgtctatag tatacccgac
     5821 ctatcttaaa caaatcttaa aaatctctta ggaccaaaca ctttctaaaa tatttgtttg
     5881 ttcacgacca ggacctactg agaaagtaga aatacgaacg ccaaccaatt cactcacacg
     5941 acgaacatag ttacgcgcat tctcaggaag atcttccaaa ttgcgagctc cggtaatatc
     6001 ttctgaccaa cctggcaact cttcatagat aggcttgcaa cgtttcaatt gctcaagact
     6061 agctggatag tagtcaatac gttgaccgtc aagatcatag gccacacaaa ttttcacagt
     6121 atccaagccg ctcaaaacat caatagagtt caaagaaagg ttagtaatac cagaaacacg
     6181 acggctatga cgcatcacaa ctgagtcaaa ccaacctaca cgacgtggac gaccagttgt
     6241 tgtaccatat tcatgaccca cttcacggat acgttctccc acttcatcaa acaactcagt
     6301 tgggaaagga ccatctccta cacgactcgt ataagcttta catacaccta caaccttgtc
     6361 aatcttgctt ggaccgatac cagaaccaat tgtcacacca ccagctacag ggtttgatga
     6421 cgtaacaaat ggataagtac cttgatcgat atctagcata acaccttgtg caccttcaaa
     6481 aagcacacgt ttgccattat caagcgcatc attcaagata acagatgtat ctatcacgta
     6541 tttcttgatt tgttgaccat attcgtaata ttcttcaaaa atatcatcga aaacaatcgc
     6601 tttactgtca tacaattttt caaaaagacg attcttttca gcaaggttac gttctaaacg
     6661 ctcacggaaa atatctttat ctaaaagatc tgcaatacga attccaacac gagcagcctt
     6721 gtccatataa gctggaccaa ttcccttaat tgtcgtacca atcttattgt cgcccttagc
     6781 ttcttcttgc aagcgatcca actcgatatg ataaggcaaa ataacatgcg cacgatcaga
     6841 aatacgcaag ttatcagttg ttacaccttc ctcatgaaga tagctcaact cttttacaag
     6901 agatttagga tttacaacca taccattccc aatgacagat attttttcag ggaagaaaat
     6961 cccagatgga atcaagtgca acttaaattt cttaccgtca atcacaatcg tgtgaccagc
     7021 attatcacca ccttggtaac gtgcaattac ttctgcattc gctgaaagga agtctgtaat
     7081 cttcccttta ccttcatcac cccattgggt acctacaaca acaactgaag tcataatttt
     7141 gtctgagccc tcaggctctt cctttctcac atacatggca ggactctcac ctgcaattat
     7201 atcttacaat ttattataat aaaaaatcgc ctttttatca agaagaaaca atagaaagat
     7261 ttgctatttc caactattaa aaaatgattt agaaaaatta ctagctattt actattatct
     7321 ttccataaaa gagtaaatta gttcggaaat ttactaaaat tacctcaaca agaaataaaa
     7381 ccccgattca ttaccaattt ttcaagatac aaacgataag caacacgata atggtaaacg
     7441 ataaaatccc tacgacaacc aatgccatat ctcactaaat aataaattaa aaatttaaaa
     7501 tgaacatgtt cccagtcaaa attatcacca aatgtaggac catactcttc ttcaatacta
     7561 tcatagaaat tagtcatctg ctcataaatt ttttgtaaca taatcaaata ctccttttct
     7621 tttttataaa cttattctaa caaaaaattt tacacattca ctatcaattc ctgaattgtt
     7681 aaaataccag cctcaacaag ataaaaatag gaaaagttga caaaatagaa acaaatttgc
     7741 tacctaaatt tcaaacgatt aaagttctaa aaagaccgcc ttaaaacttt tgggtaaatc
     7801 ctattagaac tataatattt atatatatgt attatggttc tgattttcta gtataaaaaa
     7861 attcaaacta gaattcttct tagaaaaggc cgttttaagt gctatcattg ctcaaaaatg
     7921 gaggtcgctg agacttctat cgtcaagaag aatcatcaaa ttccttgtat catcaaccaa
     7981 aagattgctc agaagttaat tgaaaagact tctatgaccg acattgatca tcagttgtct
     8041 atttcaactt caactgtcat tcgcaagatc aataattttc actttgagca tgatttttcg
     8101 cgtcttcctg agattatgtc ctaggacgtt gaaacagtcc ggggagtgac tgtttcaatc
     8161 gggagatgga gatgagcttt attgctcagg actttgataa actcaatatc ataactgttc
     8221 ttgagagcag aacacaagcc atcatccgaa atcccatgaa tacaaggcta tcaagcgcta
     8281 ctggaagctc attcaacaag atagtcagaa actgagtgat aaacgatttt atcgccctac
     8341 ttttcgtatg cacttgacta ataaagaaat tctagataaa cttttgagct attccgaaga
     8401 cttgaaacac cactataatc tctatcagct cttgcttttc cacctctgtt tcagactttg
     8461 tttaaaacct tcctcaaaga taaagagaaa atcgtcaacg cccttcaatt accttattcc
     8521 aacgccaaac tggaagccac caataatctc atcaaactta tcaagcacaa tgcctttggt
     8581 tttaggaact ttgaaaactt caaaaaagaa aggacgaaat ttgtcctttc tagatcttcg
     8641 ctttcttcaa cccactacag ttgacaaaga accgaaaaat gtctcgcctc taatatagtc
     8701 aattgaaaca agaacaagag aaaagagcct cgtaaaaggt attgcaactt ggtaatacct
     8761 ttttgaggtt ctttttgata taagcccatg ttttctcaat aggattgtac tcaggtgagt
     8821 agggaggaag aggtaaaagt ttatgcccaa actcctcgca taaaagttct aacttaccca
     8881 ttctatggaa tcttgcatta tccataataa taaccgatgg tgtggttaat gttggtaaga
     8941 gaaacttctg aaaccaagct tcaaaaaagt cgctcgtcac catctcttcg taagtcattg
     9001 gagcgattaa ctcaccattt gttagacctg caaccaaaga aatcctctga tatcttcttc
     9061 cagatacttt acctcttatt aactgacctt ttaatgagcg accatattct cgataaaaat
     9121 aagtatcgaa tcctgtttca tcaatctaaa caggtgctag gtgctttaaa ctattaaaat
     9181 t
//
LOCUS       DAVBEO010000069         8676 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 009
            SAMEA1678075-rid20185393.denovo.069, whole genome shotgun sequence.
ACCESSION   DAVBEO010000069 DAVBEO010000000
VERSION     DAVBEO010000069.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678075
            Sequence Read Archive: ERR226392
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8676)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8676)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980207.1
            Genome Coverage       :: 150x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:50:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 72 of 147
            Pseudo Genes (incomplete)         :: 72 of 147
            Pseudo Genes (internal stop)      :: 42 of 147
            Pseudo Genes (multiple problems)  :: 32 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8676
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678075-rid20185393.denovo.069"
                     /strain="KS 009"
                     /db_xref="taxon:1313"
     gene            264..1322
                     /locus_tag="VQ543_001952"
     CDS             264..1322
                     /locus_tag="VQ543_001952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2612617.1"
                     /translation="MKDDQKYLLAGLYSLLVAIFYFPLIESKGIFVSILMAVLLLYLI
                     YFIATVIHIVIIKFIRKKSFKYLVLYPFTYDGSWRFQPINLLYFPEMVRDVIPINLVQ
                     EYCQGQPYGLLKKMLKRIRLSREIALLLATIIVYFFTHRILPLSVFTFIFSYILLFAQ
                     SYLGGNTVWIGNRRLIIDDEFEKILLSKSYIKEISSARYSEYLTCEYKNLTPIILLAI
                     FENLLDSYLLQNQSEVDLDIFYKVLPLLYKEKYTMGFNYFVSLNYLLYKVGFLGIIYD
                     NEALGDLSKQYLNRNISELQDGSFDGGIQDAVASKQIVVINEFIACLNSRCMPSQYDR
                     FFYKDRPYIFSRKSPIKG"
     gene            1637..2611
                     /locus_tag="VQ543_001953"
     CDS             1637..2611
                     /locus_tag="VQ543_001953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2612618.1"
                     /translation="MKNKRYFFDTILMILLLISTIFCVSPVFIKLDILGTPSHAILTF
                     VLAIPLFYILSQCLHTLLLLVSSIFCKLRPIYFYFIFVIIIGARKYYRILFHQLMGFS
                     PGIAVFYKESQTTKNLFKFYYFLYFTTLISYYFFFTFVYDKPLLLPLIPFSIIIALVQ
                     KLYRIENQQLFLLKSKVLTILESKKNCEFNLQDYHEIWKLQSKSELPCVALSYISLIK
                     PYLSESVREQIDLLEVKRFKKINHPISLYGMLDVIKLNLYLRHYNEKNKYESMLKKIL
                     EVRPDFVLIEQNIDDSLNSSQPLSLSLAISEIQLLLEVYMGIKHVSTK"
     gene            2991..3365
                     /locus_tag="VQ543_001954"
     CDS             2991..3365
                     /locus_tag="VQ543_001954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPH_0224 family bacteriocin-like peptide"
                     /protein_id="HET2612619.1"
                     /translation="MELVLPNNYVVLEQEEMMYLDGGFSIPRWPVATAINIAFNGVLG
                     GGAISLVRNYIRNYGLRRVTSAIAGAAARYVGVRVANRVAGFALSAINGFAAWMSIGD
                     AITTIWANNDVNRRDPNLNALW"
     gene            3573..4475
                     /locus_tag="VQ543_001955"
     CDS             3573..4475
                     /locus_tag="VQ543_001955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2612620.1"
                     /translation="MIRKLIVFLLMLPLFVLWLELHVLVNNLLLNLESPLDFVISMSL
                     AFCSLILSKIVLDILYALKDLYKKEGLIKIFPFIFIRRKKVNVRFSPYFSFHRKSLSP
                     DDLRSRIIWSFILEIAIILVFILKIPFAIIMLTTIFFWTIMDINHLVFNKTEFLFNQN
                     KWQKEDSFESNLHKILMDKIQKSELSYSDLMSLLLYDAMNQSTFLTDSELFEDILKKI
                     EDSHNTLLCTGLVELLLYEISISNNNNWQEKVDKIRIQLIRINQLDFFYYTSWLRQNF
                     DFCMNREYHKMKSRKLLLSNKKIV"
     gene            4531..4770
                     /locus_tag="VQ543_001956"
     CDS             4531..4770
                     /locus_tag="VQ543_001956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate lyase"
                     /protein_id="HET2612621.1"
                     /translation="MELVLPNNYVVIDEEVMMYLDGGAYLSKRACQGICAAAGVLATA
                     AGKIAYCIGYGVLNRGCDINENPYPWDGFISATVR"
     gene            4767..5495
                     /locus_tag="VQ543_001957"
     CDS             4767..5495
                     /locus_tag="VQ543_001957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2612622.1"
                     /translation="MSNVDKIRKIHIIVCWVYIFLSFRAIINDTEYFLLIFLAFIYSI
                     VSLPLYSVKNKIVSICLVINSILLMSFPILINKFFPESFLTYTVLISVFILELAIFHL
                     IRKDFDIKLTNEYKKISQFRSKVSQSPWIKYLEISSFILTIFPSILYGKVDNHVLTLI
                     FLIKICVDTTIKFLFIRLFDTSTLMKRRIFFLFALDVIAYLFLGYLLVIQKAGYLFSV
                     LLLFSNFSVPFIKEKEYELFKNSK"
     gene            6630..6869
                     /locus_tag="VQ543_001958"
     CDS             6630..6869
                     /locus_tag="VQ543_001958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000770310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2612623.1"
                     /translation="MKLLDCILDYQERFNGKTCQVSTNYKYLEIFKVNFCLTDLHHLF
                     DLYKITRDYASQTKPAIQDGVFILEDFRNILCTMM"
     gene            7419..>8676
                     /locus_tag="VQ543_001959"
     CDS             7419..>8676
                     /locus_tag="VQ543_001959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein"
                     /protein_id="HET2612624.1"
                     /translation="MNKKKMILTSLASVAILGAGFVTSQPTFVRAEEAPVASQSKAEK
                     DYDAAVKKYEAAKKEYEDGKAAQKKYEDDQKKTEEKAEEERKASEEEQAANLKYQQEL
                     VKYIRENDPTKKAEAKKAMDEAEKEYKKKQTEFAEVRAKVIPSAEELKKTRQKAEEAK
                     AKEAELTKKVEEAEKKVTEAKQKVDAEHAEEVAPQAKIAELEHEVQKLEKALKEIDES
                     DSEDYVKEGLRAPLQFELDVKQAKLSKLEELSDKIDELDAEIAKLEKDVEDFKNSDGE
                     QAGQYLAAAEEDLVAKKAELEKTEADLKKAVNEPEKPAEETPAPAPKPEQPAEQPKPA
                     PAPQPEKPAEEPENPAPAPQPEKSADQQAEEDYARRSEEEYNRLTQQQPPKAEKPAPA
                     PQPGWKQENGMWYFYNTDGSMATGWLQ"
BASE COUNT         3005 a         1177 c         1582 g         2912 t
ORIGIN      
        1 taaatctaat aaattctatt attatagctc ttggtatgat attggcatta attttggtat
       61 tatcaagagt gtatagaaaa tatttttata gagacgatga tgactaaagt ttttatcaat
      121 aatttgggct ccttgtcaac tgtagtggat tgaagaaaag ctaacgtctg gggaagggtt
      181 taaagctttg ctttatcaaa tattgactta cagagttgct ctattgtatt gatgtattct
      241 tagtaaataa tatggtgttt tgaatgaaag atgatcagaa atatttatta gcgggacttt
      301 attcgcttct agttgcaata ttttattttc cattgattga gtccaagggg atttttgtaa
      361 gtatattgat ggcggtttta cttttatatt taatatactt cattgcaaca gtcattcata
      421 ttgtgataat taagtttata agaaaaaaat cttttaagta tttggttcta tatccattta
      481 cttatgatgg gagctggaga tttcaaccta taaacttact ctactttcca gaaatggtga
      541 gagatgtcat tccgattaat ttagttcaag aatattgcca aggacaacct tacggactgt
      601 taaaaaagat gctgaaaaga attcgattgt cacgagagat agctttactc ctggctacca
      661 ttatcgtcta tttttttacg catagaattc tacctctttc agtatttacg ttcatatttt
      721 cttacatatt gctatttgca caatcttatt tgggtggtaa taccgtttgg attggaaata
      781 gaagattaat aatagatgat gaatttgaaa aaatcttgct ttcaaaaagt tatataaaag
      841 aaatatcatc tgcacgatac tcggaatact tgacatgtga atacaaaaac cttacaccaa
      901 tcatattgtt agctattttt gaaaatttgc ttgactccta cttgcttcag aatcagagtg
      961 aggttgactt agatattttt tataaagttt tacctttgct ttataaagaa aaatatacta
     1021 tgggattcaa ttactttgta agtttaaatt atttactata taaggttgga tttttgggaa
     1081 tcatttacga taatgaagca ttaggagatt tgtcaaaaca atatttaaac agaaatattt
     1141 cggaattaca agatggttct ttcgatggcg gtatacaaga tgctgttgcc tctaaacaaa
     1201 tagtagttat aaatgaattt atagcttgtt taaattccag atgcatgcca tcccaatatg
     1261 atagattttt ttataaagat agaccttata ttttttccag aaagagtcct attaaggggt
     1321 gaaaatttgt tacatttgga ttaacaagtg tcctagggat tagaaataac tctagtatag
     1381 ctagatattt ttgagtaact agaaatatca ttaggctacc catatgattg ccagaaaaga
     1441 tggctgatga atcttattta tactgttgca gtaggcattg tctaggataa ataagctatc
     1501 ttgatggggg aaattggaat aattttagta gaaacattaa aggattatgg acaagtagcg
     1561 caggattagg tgatgcaatg tgctaagttg gcttggtgtt agcagtagta ttatttaaca
     1621 atggaaagta gactaaatga aaaataagcg ttattttttt gacacaattt taatgatttt
     1681 actgcttata agcacgatat tttgtgtcag cccagtattt ataaaattgg acatcttagg
     1741 aaccccctct catgccatct taacctttgt attggcgata ccgttattct atattttgtc
     1801 tcaatgctta catactttgc tattactagt ttcctcaatc ttttgtaaat taagaccaat
     1861 ttatttttat tttatatttg tgatcattat aggagctagg aaatactatc gaattctctt
     1921 tcaccaacta atgggattta gtccaggaat agcagtgttt tataaggaga gtcaaacaac
     1981 taagaatctg tttaaatttt actacttctt gtactttaca acactaattt catactattt
     2041 tttctttact tttgtgtatg acaaaccgtt gcttttgcct cttattccat tttctattat
     2101 catagcatta gtacaaaaac tttatagaat tgagaatcaa caattatttc tgttaaaatc
     2161 aaaggtacta acaatactgg aatctaagaa gaattgtgag tttaatcttc aggattatca
     2221 tgaaatttgg aaattgcaat caaaatctga gttgccatgc gtggctttat cttatatcag
     2281 tttgatcaag ccatatcttt cagagagcgt gcgtgaacaa attgatttat tagaagttaa
     2341 gcgatttaaa aaaataaatc atccaatatc actttatggt atgttggatg ttataaaatt
     2401 aaatctatat ttacggcatt ataatgaaaa aaataaatat gaatcaatgt taaagaaaat
     2461 tttagaggta agaccagact ttgttttaat cgagcagaat attgatgata gtttaaatag
     2521 ctcgcaacca ttatctttat ctttagccat ttcagaaatc caacttttgc ttgaagtgta
     2581 tatggggatc aaacatgttt caaccaagtg ataaaaccag aataatattt gccattatag
     2641 gggcaagttg catattagtc agtatgtatc ttattccact tattaaaact gagaataaat
     2701 tttgggaaat acttttattt atattaggtg tattgctaat tggaattgcg ttactaagtc
     2761 aaaaaaaata aattttgaaa tagtattagt gagttcgcaa tcatttattg ctagtggttt
     2821 agaactgtta agtttcaaac aataattgat tttaaacctt aggtaaccta taaaaacaaa
     2881 taaggtagag aaaggatatc ttatctaggt agctaagtga taaaaacaca gtcgtctatc
     2941 acttgttagg aaactatcct aactatgctt aataaaaaag gagaaaataa atggaactcg
     3001 tattaccaaa taattatgtt gttcttgagc aagaagagat gatgtatctt gatgggggat
     3061 tttctattcc gagatggcct gttgcaacag ccattaatat agcttttaat ggtgttttag
     3121 gtggaggagc aatcagtcta gttagaaatt atattcgtaa ttatggtttg cggcgagtta
     3181 caagcgcaat tgctggagca gctgcaagat atgttggggt acgagttgca aatagagtgg
     3241 caggatttgc actgtctgct attaatggat ttgcagcttg gatgtcaatt ggcgatgcta
     3301 ttacaacaat ctgggccaac aatgatgtaa ataggagaga cccaaattta aacgccttgt
     3361 ggtaactaga tatgggtatt aaaatggaaa aaatttttgt tattattttt tttgtatgtc
     3421 tatttatatc atccataact tttttagcct atgattttgt tagcgaagaa ataaaaaagt
     3481 tgattatttg gattaatgtc gtttttttga ttttaatcat agcaatgatg atttatccaa
     3541 aattaagaaa atgataagga cactgtaaaa ttatgatacg taaactaatt gttttcttac
     3601 taatgctccc tctttttgtc ttgtggctag agttgcatgt cctagtgaat aacttactat
     3661 tgaatctaga atctcccctt gattttgtga ttagtatgag tcttgctttc tgtagtttga
     3721 ttttatcaaa aatagtttta gacatactat acgcattgaa agatttatac aagaaagaag
     3781 gtcttattaa gatttttccc tttattttta taagaaggaa aaaagtgaat gtgagattct
     3841 cgccctattt ttcattccat cgtaaaagtt tgtcgcctga tgatttaaga tctaggatta
     3901 tatggagttt tattcttgaa attgctatta tcctagtatt tattttaaaa attccttttg
     3961 caatcatcat gcttactaca atatttttct ggactataat ggatatcaat catctcgttt
     4021 ttaataagac ggaatttctt tttaatcaaa acaaatggca aaaagaagat tcatttgaaa
     4081 gtaatttgca taagatattg atggacaaaa tacaaaaatc agaattaagc tattctgact
     4141 taatgtccct tcttctctat gatgcgatga accaatccac ctttttaacg gatagtgaac
     4201 tttttgagga tattttgaaa aaaatcgaag attctcataa cacccttctg tgtacaggtc
     4261 ttgtcgagtt actgctgtat gagatttcta ttagtaacaa taacaactgg caagaaaagg
     4321 ttgataaaat tagaatacag ctcatcagaa tcaatcaatt agattttttc tattatacaa
     4381 gttggttaag gcaaaatttt gatttctgta tgaatagaga gtatcataaa atgaaatctc
     4441 ggaaattatt actgagtaat aaaaagatag tttaagttcg tcctatttgt aaaacaaatg
     4501 aaacaatttc aactaaggag gagaaaacaa atggaacttg tattaccaaa taattatgtt
     4561 gtgattgatg aagaagtaat gatgtatctt gatgggggag cttatttaag caagcgtgct
     4621 tgtcaaggaa tttgcgcagc agcaggtgta ttggctacag cagcagggaa aatagcttac
     4681 tgtattggat atggtgttct taatagaggt tgtgatatta acgagaaccc ttatccttgg
     4741 gatggattca tatctgcaac agtaagatga gtaatgtaga taagattcga aaaatacaca
     4801 tcatcgtgtg ttgggtgtat atatttttat cattcagggc gattataaat gatacggagt
     4861 attttttgct tattttttta gcttttatct actcaatagt atcactacct ctatattctg
     4921 tgaaaaataa aatagtatct atctgtctag ttataaattc gattctgtta atgagtttcc
     4981 ccattttaat caataagttt ttcccagaaa gttttttgac ttataccgta ttaataagtg
     5041 tttttatcct agagttagca atctttcatt taattaggaa agattttgat attaaattga
     5101 ctaacgaata taagaaaatt agtcagttta gaagcaaggt gtctcaatct ccttggataa
     5161 aatatttaga gatttctagt tttatattaa ctatatttcc atctattctt tatggtaaag
     5221 ttgataatca tgtactgact cttatctttt tgataaaaat ttgtgtagat actacgataa
     5281 aatttttatt catcagatta tttgacacaa gtactttaat gaagaggaga atattttttc
     5341 ttttcgcatt ggatgttata gcttacttat ttttaggata tcttttagtg attcaaaaag
     5401 caggctattt gttttcggtt ttacttcttt tttctaattt ttcagttcca tttatcaaag
     5461 aaaaggaata cgaattattt aaaaatagca agtaatagaa atatggatta aatcttagaa
     5521 cggcttaaaa tcagatatga taaagggaaa tagtcttatc taggtaacta agtgctacaa
     5581 acacaatcga ggatcacttg ttaggattac attttaatca tgcttaataa gaatggagaa
     5641 ttcctatggg gattgtatta ctctgaagtt tcgaatacct tagttctcgt gattttgagc
     5701 tattctagct ttagaatcct tcagaacgta aaattttaag cagtcaaaga cttagaatag
     5761 cctgaaaaca tttattttat agcaattcta ggcttagaat tgctcatata tatgtatttg
     5821 agctgctcga tagttaggac agctctattc tgagaaatct gagctatcaa tgcttcagaa
     5881 tagtatttcg ccaatggttt ttattgaaga ggtgattgtg ttatgatagt ctaaaataaa
     5941 attgatttaa tagagtaaat ggagaatcgt tacatgaaac atttttttgc aggaattggt
     6001 gagataaaac ttgttggcta cttattgtat atatgtgtag gactagcccc tctttttcat
     6061 atatatgtca taggttcgga actgagtttt gtgaaaatag tgttatctat tttgggagtt
     6121 atatttgtaa gtatgttaac tattgctcga atttatcgga cttttctata aagaatagtt
     6181 tggacttaaa ctgtatctaa aaacagaggt tggtcgatta tcagcctctt tcttgtcgtt
     6241 gaaaagagtg agatatattg acttttgaaa aaaagatgtc ataattgagt tgggataaac
     6301 ctaaaagtaa tatagtagat tgaatctgga atagtccgtt atgactgtta aaatatttct
     6361 agaaattaat ttgactttcc taatcgattt gttcacatct tgtttcaatc tactatactt
     6421 tctcgttaaa ccgttcggca attcatggtg acatggacac atagtagtaa gcacactatg
     6481 tggcttggca gagctaaaaa ctgttccctt gcgataagcc taataagcac aacataggga
     6541 gttagagaag ccgactctaa tcaaccactt tgggcaatag tgagaactgc cccgtgcttt
     6601 tttattttga gaaaatatgg agtttgtcgt tgaaattact tgattgtatt ttggactatc
     6661 aagaaagatt caatggaaaa acatgtcaag tatcaacgaa ttataagtat ttagagattt
     6721 tcaaagtgaa tttttgtttg actgatttac atcatttatt tgacttatac aaaatcacac
     6781 gagattatgc tagtcaaaca aaacctgcta ttcaagatgg tgtttttatt ttagaagatt
     6841 ttagaaatat cctatgtaca atgatgtaat cgaaaggata tctttatgtg agtttatcgg
     6901 cgatatcttc tatatctaag ctagcaagtt gttgcatcgt agctaaggat ttatctaaaa
     6961 atactatgaa attggacgtc atattttttg aggataaaaa taaaagatcc gcagttttag
     7021 gtttacgaag agacaaaagc ggagtattta aaccagttac tctacatttt acaagcgcta
     7081 agaaatatgc taaagttcgt aaaacagatg tgaaagaaat gaaatggcta taaagattgt
     7141 ccgcaggctt aagcttgcgt tttttgttgt ttaacgaaat taaaaaacaa gctctctcat
     7201 cggaaatgtt tttataggaa tgaaggaaga tgatgctatg tttaaaaaga gaatcgaaaa
     7261 gggcaaaagt agtgtcttta tctttttgga gtagaagctt atgatataga aatttgtaat
     7321 aaaaatgtaa tataaaacat ttgacaaata tttacggggg gagtatactt aatataagta
     7381 tagtctaaaa atgactatca gaaaagaggt aaatttagat gaataagaaa aaaatgattt
     7441 taacaagtct agccagcgtc gctatcttag gggctggttt tgttacgtct caacctactt
     7501 ttgtaagagc agaagaagct cccgtagcta gtcagtctaa agctgagaaa gactatgatg
     7561 cagcagtgaa aaaatatgaa gctgctaaga aggaatatga ggacggaaaa gctgctcaga
     7621 aaaagtatga agatgatcag aagaaaactg aggagaaagc ggaagaagaa agaaaagctt
     7681 ctgaagaaga acaagctgca aatctgaaat atcaacaaga gttggttaaa tatatacgtg
     7741 aaaatgatcc aacaaaaaaa gctgaagcta agaaagcaat ggatgaggct gagaaagagt
     7801 ataagaaaaa acaaacggaa tttgctgaag ttcgtgcaaa ggtaattcct agcgcggaag
     7861 aattaaaaaa gactagacaa aaagcagaag aggctaaagc aaaagaagca gaacttacta
     7921 aaaaagtaga agaagctgag aaaaaagtta ctgaagccaa acaaaaagtg gatgcagaac
     7981 atgctgaaga agtcgctcct caagctaaaa tcgctgaatt ggaacatgaa gttcagaaac
     8041 tagaaaaagc tctcaaagag attgatgagt ctgattcaga agattatgtt aaagaaggtc
     8101 tccgtgctcc tcttcaattt gaattggatg ttaagcaagc taaactatca aaacttgaag
     8161 agttgagtga taagattgat gagttagacg ctgaaattgc aaaacttgaa aaagatgtag
     8221 aagatttcaa aaactcagac ggtgagcaag ctggacaata ccttgctgca gctgaagaag
     8281 acttagttgc taaaaaagct gaattagaaa aaactgaagc tgaccttaag aaagcagtta
     8341 atgagccaga aaaaccagct gaagaaactc cagctccagc accaaaacca gagcaaccag
     8401 ctgaacaacc aaaaccagcg ccggctcctc aaccagaaaa accagctgaa gagcctgaga
     8461 atccagctcc agcaccacaa ccagagaagt cagcagatca acaagctgaa gaagactatg
     8521 ctcgtagatc agaagaagaa tataatcgct tgacccaaca gcaaccgcca aaagcagaaa
     8581 aaccagctcc agcaccacaa ccaggttgga aacaagaaaa cggtatgtgg tacttctaca
     8641 atactgatgg ttcaatggct acaggttggc tacaaa
//
LOCUS       DAVBEO010000070         8604 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 009
            SAMEA1678075-rid20185393.denovo.070, whole genome shotgun sequence.
ACCESSION   DAVBEO010000070 DAVBEO010000000
VERSION     DAVBEO010000070.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678075
            Sequence Read Archive: ERR226392
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8604)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8604)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980207.1
            Genome Coverage       :: 150x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:50:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 72 of 147
            Pseudo Genes (incomplete)         :: 72 of 147
            Pseudo Genes (internal stop)      :: 42 of 147
            Pseudo Genes (multiple problems)  :: 32 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8604
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678075-rid20185393.denovo.070"
                     /strain="KS 009"
                     /db_xref="taxon:1313"
     gene            226..6657
                     /locus_tag="VQ543_001960"
     CDS             226..6657
                     /locus_tag="VQ543_001960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000750034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family serine peptidase"
                     /protein_id="HET2612625.1"
                     /translation="MKKSTVLSLTTAAVILAAYAPNEVVLADTSSSEDALNISDKEKV
                     VVDKETENKEKHEDIHNAIETSQDFKEKKTAVIEGKEVVSKNPVTDNNTSNEEARIKE
                     DSNQSQGDHTDSFVNKNTENPKKEDKVVYIAEFKDKESGEKAIKQLSNLKNTKVLYTY
                     DRIFNGSAIETTPDNLDKIKQIEGISSVERAQKVQPMMNHARKEIGVEEAIDYLKSIN
                     APFGKNFDGRGMVISNIDTGTDYRHKAMRIDDDAKASMRFKKEDLKGTDKNYWLSDKI
                     PHAFNYYNGGKITVEKYDDGRDYFDPHGMHIAGILAGNDTEQDIKNFNGIDGIAPNAQ
                     IFSYKMYSDAGSGFAGDETMFHAIEDSIKHNVDVVSVSSGFTGTGLVGEKYWQAIRAL
                     RKAGIPMVVATGNYATSASSSSWDLVANNHLKMTDTGNVTRTAAHEDAIAVASAKNQT
                     VEFDKVNIGGESFKYRNIGAFFDKNKITTNEDGTKAPSKLKFVYIGKGQDQDLIGLDL
                     RGKIAVMDRIYTKDLKNAFKKAMDKGARAIMVVNTVNYYNRDNWTELPAMGYEADEGT
                     KSQVFSISGDDGVKLWNMINPNKKTEVKRNNKEDFKDKLEQYYPIDMESFNSNKPNVG
                     DEKEIDFKFAPDTDKELYKEDIIVPAGSTSWGPRIDLLLKPDVSAPGKNIKSTLNVIN
                     GKSTYGYMSGTSMATPIVAASTVLIRPKLKEMLERPVLKNLKGDDKIDLTSLTKIALQ
                     NTARPMMDATSWKEKSQYFASPRQQGAGLINVANALRNEVVATFKNTDSKGLVNSYGS
                     ISLKEIKGDKKYFTIKLHNTSNRPLTFKVSASAITTDSLTDRLKLDETYKDEKSPYGK
                     QIVPEIHPEKVKGANITFEHDTFTIGANSSFDLNAVINVGEAKNKNKFVESFIHFESV
                     EEMEALNSNGKKINFQPSLSMPLMGFAGNWNHEPILDKWAWEEGSRSKTLGGYDDDGK
                     PKIPGTLNKGIGGEHGIDKFNPAGVIQNRKDKNTTSLDQNPELFAFNNQGINAPSSSG
                     SKIANIYPLDSNGNPQDAQLERGLTPSPLVLRSAEEGLISIVNTNKEGENQRDLKVIS
                     REHFIRGILNSKSNDAKGIKSSKLKVWGDLKWDGLIYNPRGREENAPESKDNQDPATK
                     IRGQFEPIAEGQYFYKFKYRLTKDYPWQVSYIPVKIDNTAPKIVSVDFSNPEKIKLIT
                     KDTYHKVKDQYKNETLFARDQKEHPEKFDEIANEVWYAGAALVNEDGEVEKNLEVTYA
                     GEGQGRNRKLDKDGNTIYEIKGAGDLRGKIIEVIALDGSSNFTKIHRIKFANHADEKG
                     MISYYLVDPDKDASKYEKLGEISEDKLKNAKSPEENTNNNQAKDEDSKPDEKSSVEGE
                     ASLEINKTISTIREFENKDLKKLIKKKFREVDDFTSETGKRIEEYDYKYDDKGNIIAY
                     DDGSALQYETEKLDEIKSKIYGVLSPSKDGHFEILGKISNVSKNAKVYYGNSYKSIEI
                     KATKYDSHSKTMIFDLYANINDIVDGLAFAGDMRLFVKDDNQIKAETKIRMPEKNKET
                     KAEYPYVSSYGNVIELGEGDLSKNKPDNLTKMESGKIYSDSEKQQYLLKDNIILRKGY
                     ALKVTTYNPGKTDMLEGNGVYSKEDIAKIQKANPNLRVLSETTIYADSRNVEDGRSTQ
                     AVLMSALDGFNIIRYQVFTFKMNDKGEAIDKDGNLVTDSSKLVLFGKDDKEYTGEDKS
                     NVEAIKEDGSMLFIDTKPVNLSMDKNYFNPSKSNKIYVRNPEFYLRGKISDKGGFNWE
                     LRVNESVVDNYLIYGDLHIDNTRDFNIKLNVKDGDIMDWGMKDYKANGFPDKVTDMDG
                     NVYLQTGYSDLNAKAVGVHYQFLYDNVKPEVNIDPKGNTSIEYADGKSVVFNINDKRN
                     NGFDGEIQEQHIYVNGKEYTSFDDIKQITDKTLNIKIVVKDFARNTTVKEFILNKDTG
                     EVSELKPHRVTVTIQNGKEMSSTIVSEEDFILPVYKGELEKGYQFDGWEISGFEGKKD
                     AGYVINLSKDTFIKPVFKKIEEKKEEENKPTFDVSKKKDNPQVNHSQLNESHRKEDLQ
                     REDHSQKSDSTKDVTATVLDKNNISSKSTTNNPNKLPKTGTASGAQTLLAAGIMFIVG
                     IFLGLKKKNQD"
     gene            complement(6948..7294)
                     /locus_tag="VQ543_001961"
                     /pseudo
     CDS             complement(6948..7294)
                     /locus_tag="VQ543_001961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014632353.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(7389..7574)
                     /locus_tag="VQ543_001962"
                     /pseudo
     CDS             complement(7389..7574)
                     /locus_tag="VQ543_001962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            7602..7829
                     /locus_tag="VQ543_001963"
     CDS             7602..7829
                     /locus_tag="VQ543_001963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001827253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET2612626.1"
                     /translation="MRERLLTQPLLHADETSYRVLESHSHLTYYWTFLSGKVENQAIT
                     LYHHDQSRSGSVVQEFLGDYSGYVHCDMLRQ"
     gene            7905..8457
                     /locus_tag="VQ543_001964"
                     /pseudo
     CDS             7905..8457
                     /locus_tag="VQ543_001964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007897432.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus and C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         3236 a         1233 c         1689 g         2446 t
ORIGIN      
        1 taatcttatt ttttaacgtg tgctaaaaaa taaattaatg catgttaatt tttcttgaat
       61 taaatttttt taaatgatat actgttttta tggagagata acaattatat ataaatgtac
      121 tactctattt cctagataat acttagtaaa actttttata acaaaggcta gcaaagttaa
      181 agtttattat ctattggaag ttaaataaat atgtaaggaa ttaaaatgaa aaaaagtaca
      241 gtattgtcat taaccacagc tgcagttatt ttagcagcct atgcccctaa tgaggtagtc
      301 ttagcagaca catctagctc tgaagatgct ttaaacatct ctgataaaga aaaagtagta
      361 gtagataagg aaacagaaaa taaagagaaa catgaagata ttcataatgc tatagaaact
      421 tcacaggatt ttaaagagaa gaaaacagca gtcattgagg gaaaagaagt tgttagtaaa
      481 aatcctgtga cagacaataa cactagcaat gaagaagcaa gaatcaaaga agattccaat
      541 caatcccaag gagatcatac ggactcattt gtgaataaaa acacagaaaa tcccaaaaaa
      601 gaagataaag ttgtctatat tgctgaattt aaagataaag aatctggaga aaaagcaatc
      661 aagcaactat ccaatcttaa gaatacaaaa gttttatata cttatgatag aatttttaac
      721 ggtagtgcca tagaaacaac tccagataac ttggacaaaa ttaaacaaat agaaggtatt
      781 tcatcggttg aaagggcaca aaaagtccaa cccatgatga atcatgccag aaaggaaatt
      841 ggagttgagg aagctattga ttacctaaag tctatcaatg ctccgtttgg gaaaaatttt
      901 gatggtagag gtatggtcat ttcaaatatc gatactggaa cagattatag acataaggct
      961 atgagaatcg atgatgatgc caaagcctca atgagattta aaaaagaaga cttaaaagga
     1021 actgataaaa attattggtt gagtgataaa atccctcatg cgttcaatta ttataatggt
     1081 ggcaaaatca ctgtagaaaa atatgatgat ggaagggatt attttgaccc acatgggatg
     1141 catattgcag ggattcttgc tggaaatgat actgaacaag atatcaaaaa ctttaacggc
     1201 atagatggaa ttgcacctaa tgcacaaatt ttctcttaca aaatgtattc tgacgcagga
     1261 tctgggtttg cgggtgatga aacaatgttt catgctattg aagattctat caaacacaac
     1321 gttgatgttg tttcggtatc atctggtttt acaggaacag gtcttgtagg tgagaaatat
     1381 tggcaagcta ttcgggcatt aagaaaagca ggcattccaa tggttgtcgc tacgggtaac
     1441 tatgcgactt ctgcttcaag ttcttcatgg gatttagtag caaataatca tctgaaaatg
     1501 accgacactg gaaatgtaac acgaactgca gcacatgaag atgcgatagc ggtcgcttct
     1561 gctaaaaatc aaacagttga gtttgataaa gttaacatag gtggagaaag ttttaaatac
     1621 agaaatatag gggccttttt cgataagaat aaaatcacaa caaatgaaga tggaacaaaa
     1681 gctcctagta aattaaaatt tgtatatata ggcaaggggc aagaccaaga tttgataggt
     1741 ttggatctta ggggcaaaat tgcagtaatg gatagaattt atacaaagga tttaaaaaat
     1801 gcttttaaaa aagctatgga taagggtgca cgcgccatta tggttgtaaa tactgtaaat
     1861 tactacaata gagataattg gacagagctt ccagctatgg gatatgaagc ggatgaaggt
     1921 actaaaagtc aagtgttttc aatttcagga gatgatggtg taaagctatg gaacatgatt
     1981 aatcctaata aaaaaactga agtcaaaaga aataataaag aagattttaa agataaattg
     2041 gagcaatact atccaattga tatggaaagt tttaattcca acaaaccgaa tgtaggtgac
     2101 gaaaaagaga ttgactttaa gtttgcacct gacacagaca aagaactcta taaagaagat
     2161 atcatcgttc cagcaggatc tacatcttgg gggccaagaa tagatttact tttaaaaccc
     2221 gatgtttcag cacctggtaa aaatattaaa tccacgctta atgttattaa tggcaaatca
     2281 acttatggct atatgtcagg aactagtatg gcgactccaa tcgtggcagc ttctactgtt
     2341 ttgattagac cgaaattaaa ggaaatgctt gaaagacctg tattgaaaaa tcttaaggga
     2401 gatgacaaaa tagatcttac aagtcttaca aaaattgccc tacaaaatac tgcgcgacct
     2461 atgatggatg caacttcttg gaaagaaaaa agtcaatact ttgcatcacc tagacaacag
     2521 ggagcaggcc taattaatgt ggccaatgct ttgagaaatg aagttgtagc aactttcaaa
     2581 aacacggatt ctaaaggttt ggtaaactca tatggttcca tttctcttaa agaaataaaa
     2641 ggtgataaaa aatactttac aatcaagctt cacaatacat caaacagacc tttgactttt
     2701 aaagtttcag catcagcgat aactacagat tctctaactg acagattaaa acttgatgaa
     2761 acatataaag atgaaaaatc tccatatggt aagcaaattg ttccagaaat tcacccagaa
     2821 aaagtcaaag gagcaaatat cacatttgag catgatactt tcactatagg cgcaaattct
     2881 agctttgatt tgaatgcggt tataaatgtt ggagaggcca aaaacaaaaa taaatttgta
     2941 gaatcattta ttcattttga gtcagtggaa gaaatggaag ctctaaactc caacgggaag
     3001 aaaataaact tccaaccttc tttgtcgatg cctctaatgg gatttgctgg gaattggaac
     3061 cacgaaccaa tccttgataa atgggcttgg gaagaagggt caagatcaaa aacactggga
     3121 ggttatgatg atgatggtaa accgaaaatt ccaggaacct taaataaggg aattggtgga
     3181 gaacatggta tagataaatt taatccagca ggagttatac aaaatagaaa agataaaaat
     3241 acaacatccc tggatcaaaa tccagaatta tttgctttca ataaccaagg gatcaacgct
     3301 ccatcatcaa gtggttctaa gattgctaac atttatcctt tagattcaaa tggaaatcct
     3361 caagatgctc aacttgaaag aggattaaca ccttctccac ttgtattaag aagtgcagaa
     3421 gaaggattga tttcaatagt aaatacaaat aaagagggag aaaatcaaag agacttaaaa
     3481 gtcatttcga gagaacactt tattagagga attttaaatt ctaaaagcaa tgatgcaaag
     3541 ggaatcaaat catctaaact aaaagtttgg ggtgacttga agtgggatgg actcatctat
     3601 aatcctagag gtagagaaga aaatgcacca gaaagtaagg ataatcaaga tcctgctact
     3661 aagataagag gtcaatttga accgattgcg gaaggtcaat atttctataa atttaaatat
     3721 agattaacta aagattaccc atggcaggtt tcctatattc ctgtaaaaat tgataacacc
     3781 gcccctaaga ttgtttcggt tgatttttca aatcctgaaa aaattaagtt gattacaaag
     3841 gatacttatc ataaggtaaa agatcagtat aagaatgaaa cgctatttgc gagagatcaa
     3901 aaagaacatc ctgaaaaatt tgacgagatt gcgaacgaag tttggtatgc tggcgccgct
     3961 cttgttaatg aagatggaga ggttgaaaaa aatcttgaag taacttacgc aggtgagggt
     4021 caaggaagaa atagaaaact tgataaagac ggaaatacca tttatgaaat taaaggtgcg
     4081 ggagatttaa ggggaaaaat cattgaagtc attgcattag atggttctag caatttcaca
     4141 aagattcata gaattaaatt tgctaatcat gctgatgaaa aggggatgat ttcttattac
     4201 ctagtagatc ctgacaaaga tgcttctaaa tatgaaaaac ttggtgaaat ttctgaagat
     4261 aaactcaaaa atgcaaagag cccagaggaa aataccaata ataatcaagc taaggatgaa
     4321 gattcaaaac cagatgaaaa aagttcagtt gagggagaag ctagccttga aataaataaa
     4381 actatttcaa caattagaga gtttgaaaat aaagacctaa agaaactcat taaaaagaaa
     4441 tttagagaag ttgatgattt tacaagtgaa actggtaaga gaatagagga atacgattat
     4501 aaatacgatg ataagggaaa tattattgct tatgacgatg gtagtgcctt acaatatgaa
     4561 actgaaaaac ttgacgaaat aaaatcaaaa atttatggtg ttctaagccc atctaaagat
     4621 ggacactttg aaattcttgg aaagataagc aatgtttcta aaaatgccaa ggtatattat
     4681 ggaaatagct ataaatcgat agaaatcaaa gcgactaagt atgattcaca ttcaaaaacg
     4741 atgatatttg atttatacgc taatattaat gatattgtag atggattagc ttttgctgga
     4801 gatatgagat tatttgttaa agatgacaat caaataaaag ctgaaactaa gattagaatg
     4861 cctgaaaaaa ataaggaaac taaagcagaa tatccctatg tatcaagtta tgggaatgta
     4921 atcgaattag gagaaggaga tctttcaaag aacaaaccag acaatttaac taaaatggaa
     4981 tctggtaaaa tctattctga ttcagaaaaa caacaatatc tgttaaagga taacatcatt
     5041 ctaagaaaag gctatgcact aaaagtgact acctataatc ctggaaaaac ggatatgtta
     5101 gaaggaaatg gagtctatag caaggaagat atagcaaaaa tacaaaaggc caatcctaat
     5161 ctaagagtcc tttcagaaac aacaatttat gctgatagta gaaatgttga agatggaaga
     5221 agtacccaag ctgtattaat gtcggctttg gacggcttta acattataag gtatcaagtg
     5281 tttacattta aaatgaacga taaaggggaa gctatcgata aagacggaaa tcttgtgaca
     5341 gattcttcta aacttgtatt atttggtaag gatgataaag aatacactgg agaggataag
     5401 tccaatgtag aagctataaa agaagatggc tccatgttat ttattgatac caaaccagta
     5461 aacctttcaa tggataagaa ctactttaat ccatctaaat ctaataaaat ttatgtacga
     5521 aatccagaat tttatttaag aggtaagatt tctgataagg gtggttttaa ctgggaattg
     5581 agagttaatg aatcggttgt agataattat ttaatctacg gagatttaca cattgataac
     5641 actagagatt ttaatattaa gctgaatgtt aaagacggtg acatcatgga ctggggaatg
     5701 aaagactata aagcaaacgg atttccagat aaggtaacag atatggatgg aaatgtttat
     5761 cttcaaactg gctatagcga tttgaatgct aaagcagttg gagtccacta tcagttttta
     5821 tatgataatg ttaaacccga agtaaacatt gatcctaagg gaaatactag tatcgaatat
     5881 gctgatggaa aatctgtagt ctttaacatc aatgataaaa gaaataatgg attcgatggt
     5941 gagattcaag aacaacatat ttatgtaaat ggaaaagaat atacatcatt tgatgatatt
     6001 aaacaaataa cagacaagac actaaacatt aagattgttg taaaagattt tgcaagaaat
     6061 acaaccgtaa aagaattcat tttaaataaa gatacgggag aggtaagtga attaaaacct
     6121 catagggtaa ctgtgaccat tcaaaatgga aaagaaatga gttcaacgat agtgtcggaa
     6181 gaagatttta ttttacctgt ttataagggt gaattagaaa aaggatacca atttgatggt
     6241 tgggaaattt ctggtttcga aggtaaaaaa gacgctggct atgttattaa tctatcaaaa
     6301 gataccttta taaaacctgt attcaagaaa atagaggaga aaaaggagga agaaaataaa
     6361 cctacttttg atgtatcgaa aaagaaagat aacccacaag taaaccatag tcaattaaat
     6421 gaaagtcaca gaaaagagga tttacaaaga gaagatcatt cacaaaaatc tgattcaact
     6481 aaggatgtta cagctacagt tcttgataaa aacaatatca gtagtaaatc aactactaac
     6541 aatcctaata agttgccaaa aactggaaca gcaagcggag cccagacact attagctgcc
     6601 ggaataatgt ttatagtagg aatttttctt ggattgaaga aaaaaaatca agattaagac
     6661 aaaagctata gaaaaaaatg gtttatgtac tgagattaga tagtgaggtg atgacatagt
     6721 tttgtgaaaa cagccattta taactcaatt atttagttta cttcactatt gatactattt
     6781 ggagttatta atggacttag tttagataac taatgaattg attgaaaggg ttagtattga
     6841 caatattggt catattgatt agaaaataga gtctatcaaa atttaaaggc taatagaggt
     6901 gatgagacaa tttcggctct ttgtcaactg tagtgggttg aagtcagcta agctcgagaa
     6961 aggacaaatt ttgtcctttc ttttttgata ttcagagcga tgaaaatccg ttttttgaag
     7021 ttttcaaagt ttcgaaaacc aaaggcattg cgcttgataa gtttgatgag attattggtc
     7081 gcttccagtt tggcattaga atagtgtagt tgaagggcat tgacaatctt ctctttatct
     7141 ttgaggaagg ttttagagga tgaacctgat tcagattgtc ctcaatgagt ccgaaaaatt
     7201 tgtcaggctc cttattctga aagtgaaaaa gcaagagttg atagagatta tagtggtgtt
     7261 tcaagtcttc tgaatagctc aaaagtttat ctatagtaga ttgaaactag aatagtacac
     7321 ctctgcttct aaaacattgt tagaaatcga tttgactgtc ctgaatgatt tgtcctgtta
     7381 ttatttcatt ttactataaa tccacgttta cgaatctctt tccacacttg ttcaatgggg
     7441 ttcatctctg gtgtgtatgg aggaataaat gcaaaaccaa tattagtcgg aatctttaag
     7501 gtacttgatt tatgccatat agcattgtcc ataacgagta aaagataatc atctggataa
     7561 gcttgtgaaa gctcctattc ctaaagcccc tttataacct cttgcgagag agactattga
     7621 ctcagccctt acttcatgcg gatgaaactt cttatcgggt tctagagagt catagccatc
     7681 tgacctacta ttggaccttt ttgtctggga aagttgagaa tcaagcaatc acgctgtacc
     7741 atcatgatca gagtcggagt ggttcggtag tacaagaatt cctaggagat tattctggct
     7801 atgttcattg tgatatgttg cggcagtaac ttaggacttt agtcctctag ttctgcctat
     7861 gcgatagcag tccaaggttt aggagcaagg cgacgctaag cttggtaaac tgcgaactgc
     7921 tagaagctta tcgtcaactg gaagaagctg aacttgttgg atgttgggcg catgtgagaa
     7981 ggaaattttt tgaagcgacc cccaagcaag cagataaatc atccttagga gctaaaggtt
     8041 tagcttattg tgatcagtta ttttccttgg aaagagactg ggaggctttg ccagctgatg
     8101 aacgactaca gaaacgtcaa gaacatctcc agcccctaat ggaagacttc tttgcttggt
     8161 gccgccgtca gtcagtttta gcaggttcaa aactaggaag ggcaattgaa tacagcctca
     8221 agtatgaaga aacctttaag actattttga aagacggaca tctggtcctt tccaataatc
     8281 tagctgaacg cgccattaaa tcattggtta tgggacggag taaaagagtc cagtggactc
     8341 ttttagcctg agctcagttt aaaaaagcga gggtggttat tttctcaaag ttttgaagga
     8401 gctaaagcaa gagctattat tatgagcttg ttggaaacag ctaaacgtca tcaattatag
     8461 tgcgttgaat ctataacagt acgcatcgac tgctaaaaca tttctataaa tcaattttcc
     8521 tttcctaatc gatttgttca tatcttattt caatccatta taaatagcga gaaatatcta
     8581 tcctatcttc tagaatgtct tcca
//
LOCUS       DAVBEO010000071         8109 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 009
            SAMEA1678075-rid20185393.denovo.071, whole genome shotgun sequence.
ACCESSION   DAVBEO010000071 DAVBEO010000000
VERSION     DAVBEO010000071.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678075
            Sequence Read Archive: ERR226392
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8109)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8109)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980207.1
            Genome Coverage       :: 150x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:50:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 72 of 147
            Pseudo Genes (incomplete)         :: 72 of 147
            Pseudo Genes (internal stop)      :: 42 of 147
            Pseudo Genes (multiple problems)  :: 32 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8109
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678075-rid20185393.denovo.071"
                     /strain="KS 009"
                     /db_xref="taxon:1313"
     gene            120..497
                     /locus_tag="VQ543_001965"
     CDS             120..497
                     /locus_tag="VQ543_001965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001833802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family transposase"
                     /protein_id="HET2612627.1"
                     /translation="MICQFIRDMLDLPAKNVTILEGSNIHVLPSMPYSAQDFYTSIDV
                     LAELDNGIQVIIEIQVHHQNFFINRLWAYLCSQVNQNLEKIRQREGDTHQSYKQIALV
                     YAIAIVDSNYFSDDLAFHSFIVK"
     gene            732..2123
                     /locus_tag="VQ543_001966"
     CDS             732..2123
                     /locus_tag="VQ543_001966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013193417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HET2612628.1"
                     /translation="MNKSRLGRGRHGKTRHVLLALIGILAISICLLGGFIAFKIYQQK
                     SFEQKIESLKKEKDDQLSEGNQKEHFRQGQAEVIAYYPLQGEKVISSVRELINQDVKD
                     KLESKDNLVFYYTEQEESGLKGVVNRNVTKQIYDLVAFKIEETEKTSLGKVHLTEDGQ
                     PFTLDQLFSDASKAKEQLIKELTSFIEDKKIDQDQSEQIVKNFSDQDLSAWNFDYKDS
                     QIILYPSPVVENLEEIALPVSAFFDVIQSSYLLEKDAALYQSYFDKKHQKVVALTFDD
                     GPNPATTPQVLETLAKYDIKATFFVLGKNVSGNEDLVKRIKSEGHVVGNHSWSHPILS
                     QLSLDEAKKQITDTEDVLTKVLGSSSKLMRPPYGAITDDIRNSLDLSFIMWDVDSLDW
                     KSKNEASILTEIQHQVANGSIVLMHDIHSPTVNALPRVIEYLKNQGYTFVTIPEMLNT
                     RLKAHELYYSRDE"
     gene            2237..3079
                     /locus_tag="VQ543_001967"
     CDS             2237..3079
                     /locus_tag="VQ543_001967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HET2612629.1"
                     /translation="MNTYQLNNGVEIPVLGFGTFKAKDGEEAYRAVLEALKAGYRHID
                     TAAIYQNEESVGQAIKDSGVPREEMFVTTKLWNSQQTYEQTRQALEKSIEKLGLDYLD
                     LYLIHWPNPKPLRENDAWKTRNAEVWRAMEDLYQEGKIRAIGVSNFLPHHLDALLETA
                     TIVPAVNQVRLAPGVYQEQVVAYCREKGILLEAWGPFGQGELFDSKQVQEIAANHGKS
                     IAQIALAWSLAEGFLPLPKSVTTSRIQANLDCFGIELSHEERETLKTIAVQSGAPRVD
                     DVDF"
     gene            3352..4113
                     /locus_tag="VQ543_001968"
     CDS             3352..4113
                     /locus_tag="VQ543_001968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HET2612630.1"
                     /translation="MDNLYLVKDDSQLATFRDFVVRNTEKLKDYQSFLKNELAVCDLP
                     QAVIWSDFNAATQIIRESAVPAYTNNRRMVMAPDLAVWKELYLYQLMDYECSQQTQAI
                     ESHYHSLSENFLLQIVGHELAHWSEHFLDDFDGYDSYIWFEEGMVEYISRKYFLTEEE
                     FQAEKICNQSLVELFQKKYGWHSLNDFGSSTYDKNYASIFYEYWRSFLTVDKLVENLG
                     SVQAVLDSYHLWANTEKTFPLLDWFVQQKLIEKEI"
     gene            4483..5400
                     /gene="glyQ"
                     /locus_tag="VQ543_001969"
     CDS             4483..5400
                     /gene="glyQ"
                     /locus_tag="VQ543_001969"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018163989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit alpha"
                     /protein_id="HET2612631.1"
                     /translation="MSKKLTFQEIILTLQQFWNDQGCMLMQAYDNEKGAGTMSPYTFL
                     RAIGPEPWNAAYVEPSRRPADGRYGENPNRLYQHHQFQVVMKPSPSNIQELYLESLEK
                     LGINPLEHDIRFVEDNWENPSTGSAGLGWEVWLDGMEITQFTYFQQVGGLATGPVTAE
                     VTYGLERLASYIQEVDSVYDIEWADGVKYGEIFIQPEYEHSKYSFEISDQEMLLENFD
                     KFEKEAGRALEEGLVHPAYDYVLKCSHTFNLLDARGAVSVTERAGYIARIRNLARVVA
                     KTFVAERKRLGYPLLDEETRVKLLAEDAE"
     gene            5660..7696
                     /locus_tag="VQ543_001970"
     CDS             5660..7696
                     /locus_tag="VQ543_001970"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit beta"
                     /protein_id="HET2612632.1"
                     /translation="MTKNLLVELGLEELPAYVVTPSEKQLGEKMAAFLKENRLSFEAI
                     QTFSTPRRLAVRVTGLSDKQSDLTEDFKGPAKKIALDSDGNFTKAAQGFVRGKGLTVE
                     DIEFREIKGEEYVYVTKEEVGQAVEAIVPGVVDVLKSLTFPVSMHWAGNSFEYIRPVH
                     TLTVLLDEQEFDLDFLDIKGSRVSRGHRFLGKETKIQSALSYEEDLRKQFVIADPCER
                     EQMIVDQIKEIEAKHGVRIEIDADLLNEVLNLVEYPTAFMGSFDAKYLEVPEEVLVTS
                     MKEHQRYFVVRDQDGKLLPNFISVRNGNAERLKNVIKGNEKVLVARLEDGEFFWREDQ
                     KLVISDLVEKLNNVTFHEKIGSLREHMIRTGQITVLLAEKAGLSVDETVDLARAAAIY
                     KFDLLTGMVGEFDELQGIMGEKYTLLAGETPAVAAAIREHYMPTSAEGELPESKVGAV
                     LAIADKLDTILSFFSVGLIPSGSNDPYALRRATQGVVRILDAFGWHIAMDELIDSLYA
                     LKFDSLTYENKAEVMDFIKARVDKMMGSTPKDIKEAVLAGSNFVVADMLEAASALVEV
                     SKEEDFKPSVESLSRAFNLAEKAEGVATVDSELFENDQEKALAEAVETLVLSGPASQQ
                     LKQLFALSPVIDAFFENTMVMAEDQAVRQNRLAILSQLTKKAAKFACFNQINTK"
     gene            7738..7995
                     /locus_tag="VQ543_001971"
     CDS             7738..7995
                     /locus_tag="VQ543_001971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002901318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF896 family protein"
                     /protein_id="HET2612633.1"
                     /translation="MDPKKIARINELAKKKKTEGLTPEEKVEQAKLREEYIEGYRRAV
                     RHHIEGIKIVDEEGNDVTPEKLRQVQREKGLHGRSLDDPNS"
BASE COUNT         2555 a         1431 c         1794 g         2329 t
ORIGIN      
        1 gctttctttt ccgaataaat agatagaagc atagaatcta gcaaacctag atttaaaaat
       61 gtgctataat agaaggagga aaaggaggat tctcagacat ccaggtatca gcccaactaa
      121 tgatttgtca atttatccgc gatatgctgg acttgccagc aaaaaatgtg acgattttgg
      181 agggaagtaa cattcacgtc ttgccttcca tgccctactc agcgcaagat ttctatacta
      241 gtatagacgt cttggcggag ttagataatg gaatccaagt tatcatcgaa attcaggttc
      301 atcatcagaa ttttttcatc aatcgcctat gggcttatct gtgcagtcag gttaatcaaa
      361 acctagaaaa aattcgccaa cgtgaaggtg atacccacca gagctacaaa caaatcgcac
      421 tagtatacgc tatcgcaatt gtcgatagta attacttctc agatgaccta gcttttcata
      481 gttttatagt aaaatgaaat gagaacagga caaatcgatc aggacagtca aatcgatttc
      541 taacaatgtt ttagaagtat aggtctacta ttctagcttc aatctactag aaattccata
      601 gatagaaaac tacataatct ctacagatac ggatgttgga gttgatgtaa gatgctttgg
      661 cttgctagag gaattgtgga ttgccaaatt gtatcattga aattattgct caaatttgtt
      721 atgatataaa tatgaataaa agtagactag gacgtggcag acacgggaaa acgagacatg
      781 tattattggc tttgattggt attttagcaa tttctatttg cctattaggc ggatttattg
      841 cttttaagat ctaccagcaa aaaagttttg agcaaaagat tgaatcgctc aaaaaagaga
      901 aagatgatca attgagtgag ggaaatcaga aggagcattt tcgtcagggg caagccgaag
      961 tgattgccta ttatcctctc caaggggaga aagtgatttc ctctgttagg gagctgataa
     1021 atcaagatgt taaggacaag ctagaaagta aggacaatct tgttttctac tatacagagc
     1081 aagaagagtc aggtttaaag ggagtcgtta atcgtaatgt gaccaaacaa atctatgatt
     1141 tagttgcttt taagattgaa gagactgaaa agaccagtct aggaaaggtt cacttaacag
     1201 aagatgggca accttttaca cttgaccaac tgttttcaga tgctagtaag gctaaggaac
     1261 agctgataaa agagttgacc tccttcatag aggataaaaa aatagatcaa gaccagagtg
     1321 agcagattgt aaaaaacttc tctgaccaag acttgtctgc atggaatttt gattacaagg
     1381 atagtcagat tatcctttat ccaagtcctg tggttgaaaa tttagaagag atagccttgc
     1441 cagtatctgc tttctttgat gttatccaat cttcgtactt actcgaaaaa gatgcggcct
     1501 tgtaccaatc ttactttgat aagaaacatc aaaaagttgt cgctctaacc tttgatgatg
     1561 gtccaaatcc agcaacgacc ccgcaggtat tagagaccct agctaaatat gatattaaag
     1621 cgactttctt tgtgcttggg aaaaatgttt ctgggaatga ggacttggtg aagaggataa
     1681 aatctgaagg tcatgttgtt ggaaaccata gttggagcca tccgattctc tcgcaactct
     1741 ctcttgatga agctaaaaag cagattactg atactgagga tgtgctaact aaagtgctgg
     1801 gttctagttc taaactcatg cgtccacctt atggtgctat tacagatgat attcgcaata
     1861 gcttggattt gagctttatc atgtgggatg tggatagtct ggactggaag agtaaaaatg
     1921 aagcatctat tttgacagaa attcagcatc aagtagctaa cggctctatc gttttgatgc
     1981 atgatattca cagtccgaca gtcaatgcct tgccaagggt cattgagtat ttgaaaaatc
     2041 aaggttatac ctttgtgacc ataccagaga tgctcaatac tcgcctaaaa gctcatgagc
     2101 tgtactatag tcgtgatgaa taagcaagaa aaaataggtc tgttagatat ttgacagact
     2161 tattttttac agaatatagt actacttaaa aaatgtttta tgctataatt gatgaataaa
     2221 atagaaggag aagcatatga atacctatca attaaataat ggagtagaaa ttccagtatt
     2281 gggatttgga acttttaagg ctaaggatgg agaagaagcc tatcgtgcag tgttagaagc
     2341 cttgaaggct ggttatcgtc atattgatac ggcggcgatt tatcagaatg aagaaagtgt
     2401 tggtcaagca atcaaagata gcggagttcc acgtgaagaa atgttcgtaa ctaccaagct
     2461 ttggaatagt cagcaaacct atgagcaaac tcgtcaagct ttggaaaaat ctatagaaaa
     2521 actgggcttg gattatttgg atttgtattt gattcattgg ccgaacccaa aaccgctcag
     2581 agaaaatgac gcatggaaaa ctcgcaatgc ggaagtttgg agagcgatgg aagacctcta
     2641 tcaagaaggg aaaatccgtg ctatcggcgt tagcaatttt cttccccatc atttggatgc
     2701 cttgcttgaa actgcaacta tcgttcctgc ggtcaatcaa gttcgcttgg cgccaggtgt
     2761 gtatcaagaa caagtcgtag cttactgtcg tgaaaaggga attttattgg aagcttgggg
     2821 gccttttggt cagggagaac tatttgatag caagcaagtg caagaaatcg cagcaaatca
     2881 cggaaaatcg attgctcaga tagccttggc ctggagcttg gcagaaggat ttttaccact
     2941 tccaaaatct gtcacaacct ctcgtattca agctaatctt gattgctttg gaattgaact
     3001 gagtcatgag gagagagaaa ccttaaaaac gattgctgtt caatcgggtg ctccacgagt
     3061 tgatgatgtg gatttctaga aaatcataaa aagaattgta cattattcta atttttgata
     3121 taatagtcag caggaaagaa agtcttatgg cgttcttcaa gcgagcttgg gatagtggga
     3181 gccaagtagg gcaaaataat gagctggcgc tttctgtagt attttcaaaa acaatgaagt
     3241 aataaattag ggtggaaccg cgtttctgac gcccctaggt taaatcaacc taggattgtc
     3301 ggacgcggtt cttttgctta ttcagtctat tgtgtgaaag aaaggagagc cgtggacaac
     3361 ctttatcttg taaaagacga tagtcaacta gctacatttc gtgattttgt agtaagaaat
     3421 actgaaaagt tgaaagatta tcaatctttt ttaaagaatg aacttgcagt ctgtgattta
     3481 ccgcaagccg ttatttggtc agattttaat gctgctacac agattattag ggaaagcgct
     3541 gttccagcct atacaaataa tagacgaatg gttatggcgc ctgatttagc tgtttggaaa
     3601 gagttgtatt tgtatcaatt gatggactac gagtgttctc agcaaactca agcaatagaa
     3661 agtcactatc attctttatc tgaaaatttc ctcttacaga ttgtaggaca tgagttagct
     3721 cattggtcgg agcatttttt agatgatttt gatggttatg actcttatat ctggttcgaa
     3781 gaggggatgg ttgaatatat tagtcgcaag tatttcttga cagaagagga atttcaagcg
     3841 gaaaaaattt gtaatcaatc tctcgtagaa ctttttcaga agaagtatgg ttggcattca
     3901 ttgaatgatt ttggttcttc gacttatgat aagaactatg caagtatttt ttatgaatac
     3961 tggcgcagct ttttgacagt agataagttg gtagaaaatt taggtagtgt acaagcggtc
     4021 ttagattctt atcatttatg ggcaaataca gaaaaaactt ttcccttgtt agattggttt
     4081 gttcagcaga aattaattga aaaagaaata taaaaactaa aggagtaaac aatgtctaag
     4141 aaattgacat ttcactgcgt cagtggcaga aacctcctta cagtcggact gccccacgct
     4201 cagcactaga gtgcctgagc tagacgcagt actaactcgt cttgcctcgt atgatcgacg
     4261 aggcagactc atgtcgcaag taattatttt ttattaagga gtaaacaatg tctaagaaat
     4321 taacatttca ctgcatcagt ggcagaaacc tccttacagt cggactgccc cacgctcagc
     4381 accctagtgc tgagctagac gcagtactaa ctcgtcttgc ctcgtataat cgacgaggca
     4441 gactcgtgtc gcaagaaatc attttttatt aaggagtaaa caatgtctaa gaaattaaca
     4501 tttcaagaaa ttattttgac tttgcaacaa ttttggaatg accaaggttg tatgcttatg
     4561 caggcttatg acaatgaaaa aggtgcgggg acaatgagtc cttacacttt ccttcgtgct
     4621 atcggacctg agccatggaa tgcagcttat gtagagccat cacgtcgtcc tgctgacggt
     4681 cgttatgggg aaaaccctaa ccgtctctac caacaccacc aattccaggt ggtcatgaag
     4741 ccttctccat caaatatcca agaactttac cttgagtctt tggaaaaatt gggaatcaat
     4801 cctttggagc acgatattcg ttttgttgag gacaactggg aaaacccatc aactggttca
     4861 gctggtcttg gttgggaagt ttggcttgac ggaatggaaa tcactcagtt cacttatttc
     4921 caacaagtcg gtggattggc aactggccct gtgactgcgg aagttaccta tggtttggag
     4981 cgcttggctt cttacattca agaagtagac tctgtctatg atatcgagtg ggctgatggt
     5041 gtaaaatacg gagaaatctt tatccagcct gagtatgagc actcaaaata ttcatttgaa
     5101 atttcggacc aagaaatgtt gcttgaaaac tttgataagt ttgaaaaaga agctggtcgt
     5161 gcattagaag aaggcttggt acaccctgcc tatgactatg ttctcaaatg ttcacatacc
     5221 tttaatctgc ttgacgcgcg tggtgccgta tctgtaacag agcgtgcagg ctatatcgct
     5281 cgtatccgta acttggcccg tgttgtagcc aaaacctttg ttgcagaacg caaacgccta
     5341 ggttacccac ttttggatga agaaacacga gttaaacttt tagcagaaga cgcagaatag
     5401 tgagtaatac tgtactctaa aatcgttaga ggcaagtcga agacttgcta gagggatatg
     5461 caccgccgta ctgttatgtg gggatttttg aaaccttagg ttcaaaaatc agtcagctaa
     5521 atccactttg atgagattgt tggaaatctt gataaattta gcattggatt tccatacaga
     5581 ctcacagagt tagttagcga cgtccccagt acctaaggtg catatcaaaa aagattgaag
     5641 aaaatgtaaa ggaaaaaaca tgacaaaaaa cttattagta gaactcggtc ttgaagaatt
     5701 accagcctat gttgtcacac caagtgaaaa acaactaggc gaaaaaatgg cagccttcct
     5761 caaggaaaac cgcctgtctt ttgaagccat tcaaaccttc tcaacaccac gtcgtttggc
     5821 tgttcgtgtg actggtttat cagacaaaca gtctgatttg acagaagatt tcaagggacc
     5881 agcaaagaaa attgccttgg atagtgatgg aaactttacc aaagcagctc aaggatttgt
     5941 ccgtggaaaa ggcttgactg ttgaagatat cgaattccgt gaaatcaagg gtgaagaata
     6001 tgtctatgtc actaaggaag aagttggtca agcagttgaa gccattgttc ctggtgttgt
     6061 agatgtcttg aagtcattga ctttccctgt cagcatgcac tgggctggaa atagctttga
     6121 atacattcgt cctgtccaca ctttaactgt tctcttggat gagcaagagt ttgacttgga
     6181 tttccttgat atcaagggaa gtcgtgtgag ccgtggccat cgtttcttgg ggaaagaaac
     6241 caaaattcag tcagcattga gctatgaaga agaccttcgt aagcagtttg taatcgcaga
     6301 tccatgtgaa cgtgagcaaa tgattgttga ccaaatcaag gaaattgagg caaaacatgg
     6361 tgtacgtatc gaaattgatg cggatttgct gaatgaagtc ttgaatttgg ttgaataccc
     6421 aactgccttc atgggaagtt ttgatgctaa ataccttgaa gttccagaag aagtcttggt
     6481 gacttctatg aaggaacacc agcgttactt tgttgttcgt gatcaagatg gaaaactctt
     6541 gccaaacttc atttctgttc gtaacggaaa cgcagagcgt ttgaaaaatg tcattaaagg
     6601 aaatgaaaaa gtcttggtag cccgcttgga agacggagaa ttcttctggc gtgaagacca
     6661 aaaattggtg atttcagatc ttgttgaaaa attaaacaat gtcaccttcc atgagaagat
     6721 tggttccctt cgtgaacaca tgattcgtac gggtcaaatc actgtacttt tggcagaaaa
     6781 agctggtttg tcagtggatg aaacagttga ccttgctcgt gcagcagcca tttacaagtt
     6841 tgacttattg acaggtatgg ttggtgaatt tgacgaactc caaggaatta tgggtgaaaa
     6901 atacaccctt cttgctggtg aaactccagc ggtggcagct gctattcgtg aacactacat
     6961 gcctacatca gctgaaggag aacttccaga gagcaaggtc ggcgcagttc tagccattgc
     7021 agacaaattg gatacgattt tgagtttctt ctcagtagga ttgattccat caggttctaa
     7081 tgacccttat gcccttcgtc gtgcaactca aggtgtggtt cgtatcttgg atgcctttgg
     7141 ttggcacatt gctatggatg agctgattga tagcctttat gcattgaaat ttgacagttt
     7201 gacttatgaa aataaagcag aggttatgga ctttatcaag gctcgtgttg ataagatgat
     7261 gggctctact ccaaaagata tcaaggaagc agttcttgca ggttcaaact ttgttgtggc
     7321 agatatgttg gaagcagcaa gtgctctcgt agaagtaagc aaggaagaag attttaaacc
     7381 atctgttgaa tcactttctc gtgcctttaa cctggctgag aaggcagaag gggttgctac
     7441 agttgattca gaactatttg agaatgacca agaaaaagct ttggcagaag cagtagaaac
     7501 actcgtttta tcaggacctg caagtcagca attgaaacaa ctctttgcgc ttagcccagt
     7561 cattgatgct ttctttgaaa atactatggt aatggctgaa gatcaggctg tccgtcaaaa
     7621 tcgtttggca atcttgtcac aactaaccaa gaaagcagct aagtttgctt gttttaacca
     7681 aattaacact aaataaaatt tgataaacgg actttatctt attacaaagg agaagaaatg
     7741 gatccgaaaa aaattgctcg tatcaatgag cttgctaaaa agaaaaaaac agaaggctta
     7801 acaccagaag aaaaagtgga acaagccaaa ctacgtgagg agtacatcga aggttatcgc
     7861 cgcgctgttc gtcaccacat tgaaggaatc aaaattgtgg acgaagaagg aaacgatgtt
     7921 acaccagaaa aactacgcca agtacaacgt gaaaaaggat tacatggccg tagtcttgat
     7981 gacccaaatt cataatatgt actctttctt ttaacaaaga tagatgaaac gataacaaag
     8041 agactagcag tttgtgtttg ctagtctttt ttcgctaaaa aaggaaccat aatggttcct
     8101 aaaaactat
//
LOCUS       DAVBEO010000072         7893 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 009
            SAMEA1678075-rid20185393.denovo.072, whole genome shotgun sequence.
ACCESSION   DAVBEO010000072 DAVBEO010000000
VERSION     DAVBEO010000072.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678075
            Sequence Read Archive: ERR226392
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7893)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7893)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980207.1
            Genome Coverage       :: 150x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:50:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 72 of 147
            Pseudo Genes (incomplete)         :: 72 of 147
            Pseudo Genes (internal stop)      :: 42 of 147
            Pseudo Genes (multiple problems)  :: 32 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7893
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678075-rid20185393.denovo.072"
                     /strain="KS 009"
                     /db_xref="taxon:1313"
     gene            101..1078
                     /locus_tag="VQ543_001972"
     CDS             101..1078
                     /locus_tag="VQ543_001972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HET2612634.1"
                     /translation="MLKLGVIGTGAISHHFIEAAHTSGEYQLVAIYSRKLETAATFAS
                     RYQNIQLFDQLEVFFKSSFDLVYIASPNSLHFAQAKAALSAGKHVILEKPAVTQPQEW
                     FDLIQTAEKNNCFIFEAARNYHEKAFTTIKNFLADKQVLGADFNYAKYSSKMPDLLAG
                     QTPNVFSDRFAGGALMDLGIYPLYAAVRLFEKANDATYHAQQLDNSIDLNGDGILFYP
                     DYQVHIKAGKNITSNLPCEIYTTDGTLTLNTIEHIRSAIFTDHQGNQVQLPIQQAPHT
                     MTEEVAAFAHMIQQPDLNLYQTWLYDAGSVHELLYTMRQTAGVRFEAEK"
     gene            1075..2157
                     /locus_tag="VQ543_001973"
     CDS             1075..2157
                     /locus_tag="VQ543_001973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HET2612635.1"
                     /translation="MKTKLPTEWQELSDQLGFQEFTPIQTQLFELLLAGENLLGVSQT
                     GTGKTLAYLLPSLLRLQKKKAQQLLILAPNTELAGQIFDVCKTWAEAIGLTAQLFLSG
                     SSQKRQIERLKKGPEILIGTPGRIFELIKLKKIKMMNVETIILDEFDQLLDDSQIHFV
                     EKITHYAPRDHQLVYMSATTKFDQEKIVPNTRTIDLSDQKLDNIQHFYMQVDQRHRVD
                     MLRKLAHVEDFRGLVFFNSLSDLGNAEEKLQYRDILAVSLASDVNVKFRKIILEKFKD
                     NQLTLLLATDLLARGIDIDSLECVVNFDIPRDSETYTHRAGRTGRMGKEGYVITLVTH
                     PEEIKKLKKFASIREIVLKNQELYIK"
     gene            complement(2221..3270)
                     /locus_tag="VQ543_001974"
                     /pseudo
     CDS             complement(2221..3270)
                     /locus_tag="VQ543_001974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            complement(3654..4850)
                     /gene="tuf"
                     /locus_tag="VQ543_001975"
     CDS             complement(3654..4850)
                     /gene="tuf"
                     /locus_tag="VQ543_001975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014335040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HET2612636.1"
                     /translation="MAKEKYDRSKPHVNIGTIGHVDHGKTTLTAAITTVLARRLPSSV
                     NQPKDYASIDAAPEERERGITINTAHVEYETEKRHYAHIDAPGHADYVKNMITGAAQM
                     DGAILVVASTDGPMPQTREHILLSRQVGVKHLIVFMNKVDLVDDEELLELVEMEIRDL
                     LSEYDFPGDDLPVIQGSALKALEGDSKYEDIVMELMNTVDEYIPEPERDTDKPLLLPV
                     EDVFSITGRGTVASGRIDRGIVKVNDEIEIVGIKEETQKAVVTGVEMFRKQLDEGLAG
                     DNVGVLLRGVQRDEIERGQVIAKPGSINPHTKFKGEVYILTKEEGGRHTPFFNNYRPQ
                     FYFRTTDVTGSIELPAGTEMVMPGDNVTIDVELIHPIAVEQGTTFSIREGGRTVGSGM
                     VTEIEA"
     gene            complement(5761..6630)
                     /locus_tag="VQ543_001976"
     CDS             complement(5761..6630)
                     /locus_tag="VQ543_001976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000348128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HET2612637.1"
                     /translation="MDFTWALKYATEFLGTAILIILGNGAVANVELKGTKGHQSGWIV
                     IAVGYGMGVMIPALMFGNVSGNHINPAFTLGLAVSGLFPWAQVVPYIIAQVLGAIFGQ
                     ALVVATYRPFYLKTEKPNNILGTFSTISSIDHGTKESRYAATVNGLINEFVGSFVLFF
                     AALGLTKNFFGAEVLQFMKQKAIEAGQTVDFSDLAIKAQVAPHTASGLSVAHLALGFL
                     VMALVTSLGGPTGPALNPARDLGPRLLHAFLPKSVLGEHKGDSKWWYSWVPVVAPIAA
                     AIAAVAVFKFLYL"
     gene            complement(6853..7533)
                     /locus_tag="VQ543_001977"
     CDS             complement(6853..7533)
                     /locus_tag="VQ543_001977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HET2612638.1"
                     /translation="MVPKTATSTETKTITRIIHYVDKVTNQNVKEDVVQPVTLSRTKT
                     ENKVTGVVTYGEWTTGNWDEVISGKIDKYKDPDIPTVESQEVTSDSSDKEITVRYDRL
                     STPDKPTPEKPEIPSPQEPGTPGEPTPEKPIPQPNPEHPSVPTPNPELPNQETPTPDK
                     PTPEPGTPKAETPVNPDPEVPTYETGKREELPNTGTEANATLASAGIMTLLAGLGLGF
                     FKKKEDEK"
     gene            complement(7491..>7893)
                     /locus_tag="VQ543_001978"
     CDS             complement(7491..>7893)
                     /locus_tag="VQ543_001978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001021424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="MucBP domain-containing protein"
                     /protein_id="HET2612639.1"
                     /translation="FKEADTNSASLTGNIVSEGRTVTLVYRESEAPTTATVTANYYKE
                     GSQEKLAESVIKADLAIGSEYTTESKTIEGKTTTEDKEDRVITRKTTYTLVATPANAY
                     QKTVQQLTITTVRMLRKQWFPKQQPLLRRRL"
BASE COUNT         2299 a         1646 c         1489 g         2459 t
ORIGIN      
        1 aaagctaata gcttatttga aattttctcc tctctgttgg atagtcccgt ctatctatgt
       61 tataatgaaa gaaggattta aaatcggaaa aggagtattt atgctaaaat taggtgtcat
      121 cggaactggc gctatcagcc atcatttcat agaagcagcc cataccagtg gagaatacca
      181 actggtcgca atctattcta gaaaactaga aactgcagca acctttgctt ctcgctatca
      241 gaatatccaa ctattcgatc aattagaagt cttcttcaaa tcttcttttg atttagtcta
      301 tatcgccagt ccaaactcct tacattttgc tcaggcaaaa gctgccttgt ctgctggtaa
      361 acatgttatt cttgaaaagc cagctgtcac tcaaccacaa gaatggtttg atttgattca
      421 aacagctgaa aaaaataact gttttatctt tgaagcagct cgtaattatc acgagaaagc
      481 ctttactact atcaaaaact ttttagcaga taagcaagtg ttaggagcag atttcaacta
      541 tgccaaatac tcttccaaga tgcctgactt attggctgga caaacaccaa atgtcttttc
      601 agaccgtttt gctggtggag ccctcatgga tttggggatt tatcccctct atgctgctgt
      661 tcgtcttttt gaaaaagcta atgacgcgac ttaccatgct caacagcttg acaatagcat
      721 tgacctaaat ggagatggta tcctcttcta cccagactat caagttcaca tcaaggctgg
      781 aaaaaacatc acttccaatc ttccttgcga gatttataca acagatggaa ccttgactct
      841 caacacgatt gagcatattc gctcagctat ttttaccgac caccaaggaa atcaagtcca
      901 gcttcctatc caacaggctc ctcatacgat gactgaggaa gtcgctgcat ttgcacacat
      961 gatccagcaa ccagatctga atctctacca aacttggctg tatgatgcag gctctgttca
     1021 tgagctacta tataccatgc gccagactgc tggcgttaga tttgaggcag aaaaatgaaa
     1081 accaaactac cgactgaatg gcaagaactg agtgaccaac tcggtttcca agaattcacc
     1141 cccattcaaa ctcaactatt tgagctcctt cttgctggag aaaacctcct aggagtgagc
     1201 caaaccggaa ctggtaagac cctagcgtat ctcctaccaa gtcttctcag actacaaaag
     1261 aaaaaagccc aacaactctt gattctagca ccaaacacgg aacttgctgg acagattttt
     1321 gatgtatgta aaacgtgggc agaagctatc ggattgactg ctcaactctt cctttcaggt
     1381 tcaagtcaga aacgacaaat tgaacgtctt aaaaaggggc cagaaattct gattggaact
     1441 cctggccgta tctttgaact cattaaactt aaaaaaatca agatgatgaa tgtggaaacc
     1501 atcatcctgg atgaatttga ccaattacta gatgattctc agattcactt tgtagagaaa
     1561 atcactcact acgcacctcg tgaccaccaa ctggtctaca tgagtgccac gaccaagttt
     1621 gaccaagaaa agattgtgcc gaatacacgc actattgatc tctctgatca aaaattggac
     1681 aatatccagc atttctacat gcaggtagac caacgtcatc gagtggatat gctacgaaaa
     1741 ctggctcatg tagaggattt ccgtggtcta gtcttcttca atagcctgtc agaccttggg
     1801 aatgccgagg aaaaactaca gtatcgtgat atattggctg tttccctcgc tagtgatgtt
     1861 aatgttaaat ttagaaaaat catcttagaa aagtttaaag ataaccaact aaccctgctt
     1921 cttgcaactg accttttggc tcgtggaatt gatatcgata gcctagaatg tgtcgtaaac
     1981 tttgatattc ctagagatag cgaaacctac acacaccgtg ctggccgtac tggtcgtatg
     2041 ggcaaggaag gttatgttat cactctcgtc actcatccag aagaaatcaa aaaacttaaa
     2101 aagtttgcaa gtatccgaga aattgtccta aaaaaccaag aactctatat caaataaagc
     2161 cccattgctc tatacacatc cagtgtatgg agctttttta taagcaattc aattttatac
     2221 tcatctgctt tcaaaaagca ttctagtcca tctccgatta acgatggact ttatcacctc
     2281 cttctccaat ccttgtatga catcttgaag ttgattcatg acatcttcca aaattcgaaa
     2341 ggctttattc ttaaatccac gtttacgaat ctctttccac acttgttcaa tggggttcat
     2401 ctctggtgtg tatggaggaa taaatgcaaa accaatatta gtcggaatct ttaagatact
     2461 tgatttatgc catatagcat tgtccataac gagtaaaaaa taatcatctg gataagcttg
     2521 tgaaagcttt tctaaaaagg cgttcatcca ctcagtatta catctaccag ctattaagaa
     2581 aaatgattcg cctgtatggg catcaacagc tccataacaa tagcgaaatt ctcgtatata
     2641 gtgactatgg atatgtggac ctactcctat tggagcccaa caagatccca gtttactgat
     2701 tctaccgaaa ccagcctcat cttggtacat caagcgaacc ttacgaaaac gtctactata
     2761 tttaaaacgc tttcttgtct tcttgaattg agattttatt tttagacgcg acaatggttt
     2821 gagcgtctgc tttcttagga tgttctggac gtggcataat atttcgccaa ccatggcgct
     2881 tcaacagttg atagaaggca tcacgtgtgt aggaacgacc taactccttt ttataagcct
     2941 gaaataaggc atcaattgta acaaattctc ctgcctctgc agccttcaaa tggcgggcaa
     3001 gaaagacttt ctcttcctca actgtcatat atgcatggtt acgaccacca cgtgtttctt
     3061 gaaggagaga gtcgagtccg aactcctcat atttttttac atttcgccaa atcattgttt
     3121 gattacagtc taaaagttct ataatctctt tataagattt gcccatatca gacgaaatag
     3181 aacgatttga agacgtttat gatatttagc tgtacgagag tcttttaaaa gtgttttgat
     3241 ggtttggatt tcttctttaa ttgatttcat attactattg tataatgctt tttgatttta
     3301 gtctagtatt atactcttcg aaaatctctt caaaccgcgt cagcttcgcc ttgtcgtata
     3361 gatgttactg acttcgtcag ttctatctac aacctaaaaa cagtgttttg agcagtctgt
     3421 agctaacttt ctatagtaaa atgaaataag aacaagacaa atcgatcagg acagtcaaat
     3481 cgatttctaa caatgtttta gaagtaaatg tgtactattc tagtttcaat atattatagt
     3541 ttgctctttg attttcattg agtattagtt caatatctaa aaaaagaacc ttgccaagca
     3601 agattctttt agtgtctgac ttaaataatt gttcttctgg gaactaaatc gaattaagct
     3661 tcgatttctg taaccatacc tgaaccaaca gtacgtccac cctcacggat agagaatgta
     3721 gtaccttgtt ctacggcgat tgggtgaatc aactcaacgt cgattgtcac gttatcacca
     3781 ggcattacca tttcagtacc tgctggaagt tcgattgaac ctgtaacgtc agtagtacgg
     3841 aagtagaatt gtggacggta gttgttgaag aatggagtgt gacgtccacc ttcttcttta
     3901 gtaaggatgt agacttcacc tttgaattta gtgtgtgggt tgattgaacc tggtttagcg
     3961 ataacttgtc cacgttcgat ttcatcacgt tgaacaccac gaagaaggac acctacgtta
     4021 tctccagcaa gaccttcgtc aagttgttta cggaacattt caacaccagt aacaactgct
     4081 ttttgagttt cttctttgat accaacgatt tcgatttcgt cgttgacttt aacgatacca
     4141 cggtcgatac gtcctgaagc aactgtacca cgtccagtga ttgagaatac gtcctcgact
     4201 ggaagaagca atggtttgtc agtgtcacgt tctggttctg ggatatactc atcaactgtg
     4261 ttcatcaatt ccataacgat gtcttcgtat ttagagtcac cttcaagagc tttaagtgct
     4321 gaaccttgga taactggaag atcgtcacct gggaagtcgt attctgacaa taggtcacgg
     4381 atttccattt caaccaattc aagcaattct tcgtcgtcaa ccaagtcaac tttgttcatg
     4441 aagacgataa ggtgtttaac accaacctga cgtgaaagaa ggatgtgctc acgagtttgt
     4501 ggcattggtc cgtcagttga agctactaca aggatagctc cgtccatttg agcagcacca
     4561 gtgatcatgt ttttaacgta gtccgcgtgt cctggagcgt cgatgtgagc gtagtgacgt
     4621 ttttcagttt cgtactcaac gtgcgcagtg ttgatagtga taccgcgttc gcgttcttct
     4681 ggagcagcat cgatagacgc atagtcttta ggttggttaa ctgatgaagg caagcgacgt
     4741 gccaaaacag ttgtgatagc tgcagttagg gtagttttac cgtggtcaac gtgtccgata
     4801 gtaccaatgt taacgtgtgg tttactacga tcgtattttt cttttgccat ttgagtaaaa
     4861 gcctccaata aaatatattt tatagataga cagtaggcaa tacagtctaa ctttccttac
     4921 tattttatca aatttcagct aaattgcaag tgttttacaa cgtttttgtg aattattctt
     4981 ggtaaaaatt taactaatta atagaaagta ctaaatagac ttatccttca aggagttttc
     5041 agcattatcc atccactcac ttgctgaaaa tgtaaacagt ctctggttta tatagtaaaa
     5101 tgaaacaaga atagagcaaa tcgatcagga cagtcaaatc gatttctaac aatgttttag
     5161 aagtagatgt gtactattct agtttcaatc tactatacaa cctcaaaact gtgttttgaa
     5221 caacctgcgg ctagcttctt agtttgccct ttgattttca ttgagtataa aattgcagat
     5281 aaaacgataa caatcatagg actcagcaga gtcaatgtag gtcgaagaat agccccccta
     5341 atcgcttatt ttatagcaaa atgaaataga aactgaacat tttgttgagg aaggtaaatc
     5401 aattcctcac aatgtttgag aaagaaggga ggactattcc aacttcaacc cactataaag
     5461 cagacttaca agatagggaa cccatctccg ataatatata gtagaatgaa aactgcacaa
     5521 tttgattgga gaattcaaac caatttctaa caatgtttta gaaacaaggg tctattattt
     5581 caactgcaac ctactatagc ccattgaagc tggaatagcc cactgagact tctaaaccac
     5641 tgctggagag gagtttgttt agagtttctt tcatttccct aaaaaatcaa aaagagagaa
     5701 ccagtctgat cctctcttac ttatagatgg tgctcactca aatgttaaag gagctatttc
     5761 ttagagataa aggaatttga atacagctac tgccgcaatt gctgctgcga taggtgctac
     5821 tactggtacc caagaatacc accattttga atcgccttta tgctcaccaa gaactgattt
     5881 tggaaggaaa gcatgaagga gacgtggtcc caagtcacgg gctgggttca aggcaggtcc
     5941 tgtaggtcct ccaagtgatg ttaccaaagc cataacgagg aatccaagtg ccaagtgagc
     6001 cacagaaagt cctgaagcag tgtgtggagc cacctgtgct ttaatagcca agtcagaaaa
     6061 atcaactgtt tgtcctgctt ctattgcctt ttgtttcatg aattgaagca cttcagcacc
     6121 aaagaagttt ttagtcaaac caagagctgc aaagaacaaa acaaatgaac caacaaactc
     6181 attaatcaaa ccattgacag ttgctgcata gcgactttct tttgtaccat ggtcaatact
     6241 tgaaatagtt gagaaagttc ccaagatgtt atttggtttt tcagttttca agtagaatgg
     6301 acggtatgtt gccacaacta aggcttggcc aaagatagcc cccaagactt gcgcgataat
     6361 gtaaggtacc acttgtgccc aagggaaaag accgctaact gcaagcccta gagtgaaagc
     6421 agggttgatg tgattcccag atacgttacc aaacatcaag gctgggatca taacccccat
     6481 accataacca acagcgatga cgatccagcc actttggtga cctttcgtac ctttaagttc
     6541 aacgttggca actgcaccat tcccaagaat gatcaaaatg gcagttccca aaaattcagt
     6601 ggcatacttc agtgcccatg tgaaatccat ttgctagatt ctccttaaaa ttttttagat
     6661 attccttatt ttatcaattt ttaccctatt tagcaactga tttctggaaa tatttttaaa
     6721 aaaataggat tcatagtttc ccagttcaac gtacttgtaa gcgtttttat tcttcacgaa
     6781 agacctcatt ctcaaaacca ggaaaaagcc cacatctgtg atcttttcct ggttcctaga
     6841 ttctaaaatc tattattttt catcttcttt tttcttgaag aatcctaatc ctagaccagc
     6901 taacaaggtc atgataccag cactagccaa ggtagcatta gcttctgtac ctgtgtttgg
     6961 caattcctct ctcttacctg tctcataagt cggaacttct gggtctggat tcactggagt
     7021 ttcagctttt ggagtacctg gttctggagt tggtttatct ggtgttggag tctcttgatt
     7081 tggtagttct gggtttggtg tcggaacact tggatgctct ggatttggtt gtgggattgg
     7141 tttttctgga gtcggttcac ctggagtacc tggttcctga ggacttggaa tttctggttt
     7201 ttctggagtt ggtttatctg gtgttgataa acggtcatac cttaccgtta tttctttatc
     7261 actagagtct gacgtaactt cttgtgattc aactgttgga atatctggat ctttgtactt
     7321 gtcaatctta ccagatataa cctcgtccca gtttcctgtt gtccattcac cgtaggttac
     7381 aactcccgtg accttgttct cagtttttgt acggcttaag gttacaggtt gaacaacatc
     7441 ttcttttaca ttttggttcg taactttatc aacgtaatga atgatacgcg ttatagtctt
     7501 cgtctcagta gaggttgctg ttttgggaac cactgtttcc tcaacattct cacggtagta
     7561 atagtcaact gttgcaccgt cttctggtac gcatttgcag gagttgctac caaggtgtat
     7621 gttgttttcc ttgtgataac tcggtcttct ttgtcctcag ttgttgtttt cccttcaata
     7681 gtttttgatt ctgtggtata ctcagaacct atcgctaaat cagcttttat aacagactct
     7741 gccaacttct cttggctacc ttctttatag taattggctg ttactgtagc agtggttggc
     7801 gcttcgcttt ctctataaac taaggtcact gttctacctt cgcttacaat attcccagtt
     7861 aaacttgcag aatttgtatc tgcttcttta aaa
//
LOCUS       DAVBEO010000073         7653 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 009
            SAMEA1678075-rid20185393.denovo.073, whole genome shotgun sequence.
ACCESSION   DAVBEO010000073 DAVBEO010000000
VERSION     DAVBEO010000073.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678075
            Sequence Read Archive: ERR226392
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7653)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7653)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980207.1
            Genome Coverage       :: 150x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:50:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 72 of 147
            Pseudo Genes (incomplete)         :: 72 of 147
            Pseudo Genes (internal stop)      :: 42 of 147
            Pseudo Genes (multiple problems)  :: 32 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7653
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678075-rid20185393.denovo.073"
                     /strain="KS 009"
                     /db_xref="taxon:1313"
     gene            <1..1039
                     /locus_tag="VQ543_001979"
     CDS             <1..1039
                     /locus_tag="VQ543_001979"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018351.1"
                     /note="Produces ATP from ADP in the presence of a proton
                     gradient across the membrane. Subunit I is part of the
                     membrane proton channel; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="V-type ATP synthase subunit I"
                     /protein_id="HET2612640.1"
                     /translation="IKVMDERFGHSIYIYESETLSDNQDEIPIKLTNHSLIEPFELLT
                     EMYALPKYYEKDPTPVLAPFYFTFFGMMVADLGYGLLLFLGTMLALKIFHLPSETKRF
                     LKFFNILGVAVAIWGGIYGSFFGYELPFHLISTTSDVMIILVVSVVFGFITVFAGLLA
                     SGLQKVRMKKYAEAYNSGFVWCVILLGLLFIAVGMLMPDMRLLFVLGKWVSIFNAVGI
                     LVVSIIQAKSLSGIGAGLFNLYNISSYIGDLVSFTRLMALGLSGASIASAFNLIVGLF
                     PGTLAKLTIGLVLFILLHAINIFLSLLSGYVHGARLIFVEFFGKFYEGGGKPFQPLKA
                     SEKYIKVITKN"
     gene            1055..1531
                     /locus_tag="VQ543_001980"
     CDS             1055..1531
                     /locus_tag="VQ543_001980"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit K"
                     /protein_id="HET2612641.1"
                     /translation="MEHLATYFSTYGGAFFAALGIVLAVGLSGMGSAYGVGKAGQSAA
                     ALLKEQPEKFASALILQLLPGTQGLYGFVIGILIWLQLTPELPLEKGVAYFFVALPIA
                     IVGYFSAKHQGNVAVAGMQILAKRPKEFMKGAILAAMVETYAILAFVVSFILTLRV"
     gene            1565..2146
                     /locus_tag="VQ543_001981"
     CDS             1565..2146
                     /locus_tag="VQ543_001981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000067169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2612642.1"
                     /translation="MSNLENLRESVIEQAHEKGRMKLLDSKKKIDDEFEMQKSVIVKK
                     KEVEHERKLKELQQKYQIIFQQLKNKERQSTLVSKQKILKELFQSALIEMESWSADKE
                     MEFIYRILERYSQQEVIVTFGERTLAKFNLEQLEKLKFSFPNHLFSEQPISNESGLLI
                     SIGKIDDNYLYKTLIGSISKEESSSIANQIFIN"
     gene            2211..3218
                     /locus_tag="VQ543_001982"
     CDS             2211..3218
                     /locus_tag="VQ543_001982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000380539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATPase subunit"
                     /protein_id="HET2612643.1"
                     /translation="MDTNLFSKINTTISVKENDFITEDKFQKIIQSKDTETMAFILEA
                     TPYHLSIDVLENPSQTETSLMTKLVNDYRWAYAESPSNKIVTLFALRYVYHNIKVLLK
                     SKAAIKKDFSKLLIPIGIFDIESLKHLVSSLHSDTLPDFMVHEVESIWNEYETFNNIR
                     VLDVGADLAYFKHLKLLSNELDEVLSQVIVAMIDFYNIITVKRGLSQNKSHGDILQLL
                     SDEGSISAKEFIYIVENQEIFVWFNKINPSLDSIFSTYELKMQDATISSSELEFLCDL
                     LLYKILDQGRYNVDGPLVLARYLLGCEFEVKNLRMIISALQNTIPFGSIKERIRPHYG
                     S"
     gene            3208..3528
                     /locus_tag="VQ543_001983"
     CDS             3208..3528
                     /locus_tag="VQ543_001983"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000387939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit F"
                     /protein_id="HET2612644.1"
                     /translation="MEANKYKIGIIGSRDIILPFSMIGFDIFPAYQEQEAINTLRKLA
                     QSDYGVIYITEDIASMILDTIRHYDSQVVPAIILLPTHKQGLNLGLKRIEDNVEKAVG
                     HNIL"
     gene            3591..5366
                     /locus_tag="VQ543_001984"
     CDS             3591..5366
                     /locus_tag="VQ543_001984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit A"
                     /protein_id="HET2612645.1"
                     /translation="MTQGKIIKVSGPLVIASGMQEANIQDICRVGKLGLIGEIIEMRR
                     DQASIQVYEETSGLGPGEPVVTTGEPLSVELGPGLISQMFDGIQRPLDRFKLATHNDF
                     LVRGVEVPSLDRDIKWHFDSTIAIGQKVSTGDILGTVKETEVVNHKIMVPYGVSGEVV
                     SIASGDFTIDEVVYEIKKLDGSFYKGTLMQKWPVRKARPVSKRLIPEEPLITGQRVID
                     TFFPVTKGGAAAVPGPFGAGKTVVQHQVAKFSNVDIVIYVGCGERGNEMTDVLNEFPE
                     LIDPNTGQSIMQRTVLIANTSNMPVAAREASIYTGITMAEYFRDMGYSVAIMADSTSR
                     WAEALREMSGRLEEMPGDEGYPAYLGSRIAEYYERAGRSQVLGIPEREGTITAIGAVS
                     PPGGDISEPVTQNTLRIVKVFWGLDAPLAQRRHFPAINWLTSYSLYKDSVGIYIDGKE
                     KTDWNSKITRAMNYLQRESSLEEIVRLVGIDSLSDNERLTMEIAKQIREDYLQQNAFD
                     SVDTFTSFAKQEAMLSNILTFADQANHALELGSYFTEIMEGTVAVRDRMARSKYVSED
                     RLDEIKIISNEITHQIHLILETGGL"
     gene            5367..6752
                     /locus_tag="VQ543_001985"
     CDS             5367..6752
                     /locus_tag="VQ543_001985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000111247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit B"
                     /protein_id="HET2612646.1"
                     /translation="MSVIKEYRTASEVVGPLMIVEQVNNVSYNELVEIQLHNGEIRRG
                     QVLEIHEDKAMVQLFEGSSGINLEKSKIRFAGHALELAVSEDMVGRIFNGMGKPIDGG
                     PDLIPEKYLDIDGQAINPVSRDYPDEFIQTGISSIDHLNTLVRGQKLPVFSGSGLPHN
                     ELAAQIARQATVLNSDENFAVVFAAMGITFEEAEFFMEELRKTGAIDRSVLFMNLAND
                     PAIERIATPRIALTAAEYLAFEKDMHVLVIMTDMTNYCEALREVSAARREVPGRRGYP
                     GYLYTNLSTLYERAGRLVGKKGSVTQIPILTMPEDDITHPIPDLTGYITEGQIILSHE
                     LYNQGYRPPINVLSSLSRLKDKGSGEGKTRGDHAPTMNQLFAAYAQGKKVEELAVVLG
                     ESALSDVDKLYVRFTKRFEEEYINQGFYKNRNIEDTLNLGWELLSILPRTELKRIKDD
                     LLDKYLPLVEV"
     gene            6775..7386
                     /locus_tag="VQ543_001986"
     CDS             6775..7386
                     /locus_tag="VQ543_001986"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000251933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit D"
                     /protein_id="HET2612647.1"
                     /translation="MVRLNVKPTRMELNNLKERLKTAERGHKLLKDKRDELMRRFISL
                     IRENNRLRKEVESYLIDNLKSFAVAKSLKNSLMVEELFSIPSKEIELFIEKENIMSVT
                     VPRMHMNITSQNENSEYSYLSSNSEMDDVFATMNSLIDKLLRLAEVEKTCQLMADEIE
                     KTRRRVNGLEYSIIPNLSETIHYIELKLEEAERANLVRIMKVK"
     gene            complement(7497..>7653)
                     /locus_tag="VQ543_001987"
     CDS             complement(7497..>7653)
                     /locus_tag="VQ543_001987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HET2612648.1"
                     /translation="YSNAKLEATNNLIKLIKRNAFGFRNFENFKKRIFIALNIKKERT
                     KFVLSRA"
BASE COUNT         2508 a         1067 c         1559 g         2519 t
ORIGIN      
        1 tataaaagtt atggatgagc gttttggaca ttctatttat atttatgaat cggaaacatt
       61 gtcggataat caagatgaaa tacctatcaa attaacgaat cattctttaa ttgaaccatt
      121 tgaattattg acagaaatgt atgctctgcc caaatattat gagaaagatc ctacacctgt
      181 attagcacca ttttacttta cattttttgg aatgatggtt gctgatttag gctatggttt
      241 actattgttt ttaggaacaa tgttagcatt aaaaattttt catctacctt cagaaactaa
      301 gagattttta aaattcttta atatattagg ggtagccgtt gcaatttggg gtggaatcta
      361 tggctcattt tttggatatg agttgccatt tcatctgata tctacaacct ctgatgtcat
      421 gattatatta gtagtgtcag ttgtgtttgg gtttattaca gtatttgcag gtttgttagc
      481 ttcaggacta caaaaagtaa gaatgaagaa atatgcagaa gcatataatt caggatttgt
      541 gtggtgtgtt attctgcttg gcttgttatt tattgctgtc ggaatgttga tgcctgatat
      601 gagactgtta tttgtattag ggaaatgggt atctattttt aatgctgtgg gaattttggt
      661 tgtttctatt attcaagcca aaagcttgtc aggtattgga gcaggattgt ttaatctata
      721 taacatttca tcttatatag gtgatttagt tagtttcact cgattgatgg cattaggatt
      781 atctggagca agtatagcat cagctttcaa tttaattgtt ggtttgtttc cgggaacatt
      841 ggctaaacta acaattggat tagtattatt cattctttta catgcgatca atatttttct
      901 atcgttacta tcaggatatg ttcatggagc acgtctgata tttgttgaat tttttggtaa
      961 gttttatgag ggtggaggaa aaccatttca acctttgaag gcttctgaga aatatattaa
     1021 ggttattaca aagaattaat ggaggatata tataatggaa catttagcaa cttatttttc
     1081 aacctatgga ggagctttct tcgctgcatt gggaattgta ttggcggttg gattaagtgg
     1141 tatggggtct gcttatggag ttggtaaggc tgggcaatct gccgcagctt tactgaaaga
     1201 acagccagaa aagtttgcct ctgctttgat attgcaatta ctgcccggaa cacaaggatt
     1261 atatggtttt gttattggaa ttttgatttg gttgcaatta actccagaac ttcctttaga
     1321 aaaaggcgtt gcttatttct ttgtagctct tccaattgct attgtaggat acttttcggc
     1381 taagcatcaa ggaaatgtag cagtagcggg aatgcaaatc ttggctaaaa gaccaaaaga
     1441 attcatgaag ggagcaattt tggctgccat ggtagaaacc tatgcaattc ttgcctttgt
     1501 cgtatcattc attttgaccc ttcgtgtata agaaattaat ttgctattca aaggaggtgt
     1561 ctaaatgagc aatttagaaa acttacgaga gtctgttatt gaacaagctc atgaaaaagg
     1621 gcgtatgaaa ttattggatt ccaaaaagaa gattgatgat gaatttgaaa tgcaaaagtc
     1681 ggtcattgta aagaaaaaag aagtggaaca tgaacgaaag ttaaaagaat tacaacagaa
     1741 atatcaaata atttttcaac aattaaaaaa taaggaacgc caatcaacgt tagtatcaaa
     1801 acagaaaata ttaaaagaac tttttcaatc tgctttaata gaaatggaat cttggagtgc
     1861 agataaagaa atggagttca tctatcgaat tctggaacga tattcacaac aagaggtcat
     1921 agtaactttt ggggagcgga ctttagctaa attcaatctg gaacaattag agaaattgaa
     1981 attctctttt ccaaatcatt tatttagtga acagcctatc tcaaatgaat caggcttact
     2041 tatttcaata ggtaaaattg atgataacta tttgtataaa acattaattg gatcgatttc
     2101 taaggaagaa agttcaagta tcgcaaatca aatttttatc aattaaggat gaaattggtt
     2161 aatccttctt agaaatttgg agtattccaa taaaattaga aaggtatttt atggatacta
     2221 atcttttttc aaaaataaat acgacgattt cggtaaaaga aaacgatttt attacagaag
     2281 ataaatttca aaaaattata caatccaaag atacggagac aatggcattt atcttagaag
     2341 caactcccta tcatttatcg attgacgttt tagaaaatcc tagtcagaca gagacttcgc
     2401 taatgacaaa attagtcaat gattatagat gggcctatgc tgaaagtccg tctaataaaa
     2461 ttgtgacttt atttgcttta cgatatgttt atcataatat caaagtttta ttaaaatcta
     2521 aggcggcaat taagaaagat ttttctaaat tattaattcc aatagggatt tttgatatag
     2581 aaagtttaaa acatttagtt tcttccttac attcagatac acttcctgat tttatggttc
     2641 atgaagtaga atcaatttgg aatgagtatg aaacttttaa taatattcgt gtacttgatg
     2701 tcggagctga tctagcatat tttaaacatc tgaaactttt atctaatgag ttagatgagg
     2761 tgctgtctca ggttattgtc gcaatgattg acttttataa tattattact gtaaaacgtg
     2821 gtttatctca aaataagagt catggggata ttttacaatt actttcagat gaaggaagta
     2881 tttctgctaa agaatttata tacattgtag aaaatcaaga aatatttgtg tggttcaata
     2941 aaataaatcc aagcttagat tcaatctttt caacttatga attgaagatg caggacgcaa
     3001 caatttcatc ttctgagtta gaatttttat gtgatttatt attgtataaa attttagatc
     3061 aaggaaggta caatgtagat gggccgttag tacttgctag atatttattg ggatgtgagt
     3121 ttgaagtaaa gaatctcaga atgattatat cagctcttca aaatacaatt ccctttggat
     3181 caataaaaga aaggatacgc ccgcattatg gaagctaata agtataaaat tggcataatt
     3241 ggtagccgtg atattatttt accctttagc atgattgggt ttgatatatt tcctgcctat
     3301 caagaacaag aagctataaa tactctaaga aaattagccc aatctgatta tggtgtcatt
     3361 tatatcactg aagacattgc ttcaatgata ttagatacaa ttcgccatta tgattctcaa
     3421 gttgtgcctg ctattatttt attaccgact cataaacaag gtttaaattt aggattaaaa
     3481 cgtatagagg ataatgtgga gaaagcagta ggacacaata ttttataata atgtacaaaa
     3541 ttgtctgtaa tattattcta taatttttgg acttagtaag gagaataact ttgactcaag
     3601 ggaagattat aaaagtatcg ggacctctag ttattgcatc aggtatgcag gaggctaata
     3661 ttcaagatat ttgccgtgta ggtaagctag ggttaatcgg tgaaattatt gaaatgagaa
     3721 gagatcaggc atctatccaa gtctatgagg aaacatctgg tcttggtccg ggagaacctg
     3781 ttgttacaac tggagaacct ctctcggttg aattaggacc aggattgatt tctcaaatgt
     3841 ttgatggcat acaacgccca ttagatcgat ttaaattggc tactcataat gattttctag
     3901 ttcgtggggt agaagttcca agtttggata gagatattaa gtggcatttt gattccacta
     3961 tagcaattgg tcaaaaagtg agtacgggtg atattctagg aactgtcaag gaaaccgagg
     4021 tagttaatca taaaattatg gttccttatg gagtatctgg cgaagtcgtt tctatcgcat
     4081 ctggcgattt tacaattgat gaagttgtat atgaaataaa aaaattggac ggtagtttct
     4141 ataaaggaac gcttatgcaa aaatggcctg ttcgcaaggc gcgtcctgtt tctaaacgtt
     4201 taatcccaga agaaccatta atcacaggtc aacgagttat tgatacattc tttccagtaa
     4261 ccaaaggggg agcagcagct gttcctggac cgtttggagc aggaaagaca gttgtacaac
     4321 accaagtagc taaattttcc aatgttgata ttgttattta tgtcggttgt ggagaacgtg
     4381 gaaatgaaat gacggatgta ctgaatgagt ttcctgagtt gattgaccct aataccggac
     4441 aatcaattat gcaacggaca gttctgattg ctaatacttc aaatatgcct gttgctgctc
     4501 gtgaggcttc aatttataca ggaattacca tggctgagta ttttcgtgat atgggctact
     4561 ctgtcgccat tatggctgat tcgacttcac gttgggcaga agcactacgt gaaatgtcag
     4621 gacgtctaga agaaatgcct ggtgatgagg gttatcctgc ttatctggga agtcgtatcg
     4681 ctgaatatta tgaaagagcg ggacgttctc aggttctagg gattccagaa cgtgaaggaa
     4741 ctattactgc tattggagct gtatcgccac ccggtggaga tatttcagaa ccagttactc
     4801 aaaacacttt acggattgtg aaagtttttt gggggcttga tgctccgttg gcacagagac
     4861 gtcattttcc tgcaattaac tggcttacat cttattcact ctataaagac agtgtgggaa
     4921 tttatataga tggtaaagag aagacagatt ggaatagtaa aataactcgt gcgatgaact
     4981 acttacaacg ggaatctagt ttagaggaaa ttgttcgtct tgttggaatt gattctctgt
     5041 ctgataatga acgactaacg atggaaattg ctaaacaaat tcgagaagat tatttgcaac
     5101 agaatgcttt tgattcagta gatacattca cttcgtttgc aaaacaagaa gcaatgctaa
     5161 gtaatatcct aacttttgct gatcaggcaa atcatgcttt agagttaggt tcttacttta
     5221 cagagattat ggaaggtacc gtggcagttc gagaccgtat ggcgcgaagt aaatatgttt
     5281 cagaagatag attagatgaa atcaaaatta tttcaaatga gattacacat caaattcatt
     5341 tgatattaga aacaggaggt ctataaatga gtgttataaa agaatacaga actgctagtg
     5401 aagttgttgg gcctcttatg attgttgaac aagtaaataa tgtgtcttac aatgagttag
     5461 ttgaaattca acttcataat ggagaaattc gtcgtggaca agttttagag attcacgaag
     5521 ataaagcaat ggttcaactt tttgaaggat ctagtggaat aaatttagaa aagtctaaaa
     5581 ttcgttttgc tggtcatgca ctagaattgg ctgtatctga ggatatggtt ggtcgtattt
     5641 ttaatgggat gggaaaacca attgatggtg gaccagattt aattccagag aaatatttag
     5701 atattgatgg tcaagctatt aatcctgtat ctagagatta tccagatgaa tttattcaga
     5761 cagggatctc ctctattgat catttgaata ctcttgtacg tggtcaaaaa ttaccagtat
     5821 tttcaggttc gggcttacct cataatgaat tagcagctca gatagcaaga caagcgactg
     5881 ttttaaattc tgatgaaaat tttgcggttg tatttgcagc aatgggtatt acttttgaag
     5941 aagctgagtt ttttatggaa gaactcagaa aaacaggagc gatcgatcgt tcagtcttat
     6001 ttatgaactt ggcaaatgat cctgcaattg agcgtattgc aactccccgc attgctttaa
     6061 ccgcggcaga gtatctagct tttgaaaaag atatgcacgt tctagttatc atgacggata
     6121 tgactaacta ttgtgaagcg ttacgtgaag tctcggcagc gcgccgtgaa gttccaggta
     6181 gacgaggcta tccgggatat ttatatacaa atttatcaac tctatatgaa agggctggtc
     6241 gcttagttgg taaaaaaggt tcagtgacac agattcctat tttaacaatg ccagaagatg
     6301 acataacaca tccaattcct gatttaactg gatacattac tgaagggcaa attattttgt
     6361 ctcatgagtt gtataatcaa ggttatcgtc caccaatcaa tgttttatct tctctctctc
     6421 gattaaaaga taagggatct ggagaaggta aaactcgtgg agatcatgct ccaactatga
     6481 atcaactgtt tgcagcctat gcccaaggga aaaaggttga agagttagca gtagtattag
     6541 gagaatcggc tttatctgat gtagataaat tgtatgtgag atttacaaag cgttttgaag
     6601 aagagtacat caaccaagga ttttataaaa atcgaaatat agaagatacg ttgaatcttg
     6661 ggtgggaatt actatcaatt cttcctagaa cagagttaaa acgtatcaaa gatgatttgc
     6721 ttgataaata tttacctttg gtagaagttt aatccagaaa tggagtgatt atctatggta
     6781 cgtttgaatg taaaaccaac tcgtatggaa ttgaataact taaaggaacg tttgaaaaca
     6841 gctgaacgtg gacataagtt attaaaggat aaaagagatg aattgatgag gcgatttatt
     6901 tctttgattc gtgagaataa tcgacttcgg aaagaagtag aaagttatct aattgataat
     6961 ctaaaatctt ttgcagttgc taaatcatta aagaactctc taatggtgga ggaattattt
     7021 tcaattccat cgaaagaaat tgaattattt attgagaaag aaaatatcat gagtgtaaca
     7081 gttcctagaa tgcatatgaa tattacttct caaaatgaga acagtgaata cagctattta
     7141 tcttctaata gtgaaatgga tgatgtattt gctacaatga atagtttaat tgataaatta
     7201 ctaagactgg cagaagttga aaaaacgtgt cagttaatgg ctgatgaaat agaaaaaaca
     7261 cgtagacgtg taaatggttt agaatattcg attattccaa acttgtcgga aactattcat
     7321 tatatagaat tgaaactaga ggaggcagaa agagccaatt tagttcgtat tatgaaagtg
     7381 aagtagttcc tttatttaga tttttaatta gatgaacaaa tatcagcttg gataaggcgg
     7441 taagcctttc taagcttttt taggctcttt gtcaactgta gtgggttgaa aaaaagctaa
     7501 gctcgagaaa ggacaaattt cgtcctttct tttttgatat tcagggcgat aaaaatccgt
     7561 tttttgaagt tttcaaagtt ccgaaaacca aaggcattgc gcttgataag tttgatgaga
     7621 ttattggtcg cttccaattt ggcgttagaa tag
//
LOCUS       DAVBEO010000074         7220 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 009
            SAMEA1678075-rid20185393.denovo.074, whole genome shotgun sequence.
ACCESSION   DAVBEO010000074 DAVBEO010000000
VERSION     DAVBEO010000074.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678075
            Sequence Read Archive: ERR226392
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7220)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7220)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980207.1
            Genome Coverage       :: 150x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:50:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 72 of 147
            Pseudo Genes (incomplete)         :: 72 of 147
            Pseudo Genes (internal stop)      :: 42 of 147
            Pseudo Genes (multiple problems)  :: 32 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7220
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678075-rid20185393.denovo.074"
                     /strain="KS 009"
                     /db_xref="taxon:1313"
     gene            231..645
                     /locus_tag="VQ543_001988"
                     /pseudo
     CDS             231..645
                     /locus_tag="VQ543_001988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000720030.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(684..1127)
                     /locus_tag="VQ543_001989"
     CDS             complement(684..1127)
                     /locus_tag="VQ543_001989"
                     /EC_number="3.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-tyrosyl-tRNA(Tyr) deacylase"
                     /protein_id="HET2612649.1"
                     /translation="MKIIIQRVKKAQVSIEGQIQGKINQGLLLLVGVGPEDQEEDLDY
                     AVRKLVNMRIFSDAEGKMNLSVKDIEGEILSISQFTLFADTKKGNRPAFTGAAKPDMA
                     SDFYDAFNQKLAQEVPVQTGIFGADMQVELVNNGPVTIILDTKKR"
     gene            complement(1157..3379)
                     /locus_tag="VQ543_001990"
     CDS             complement(1157..3379)
                     /locus_tag="VQ543_001990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019316080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional (p)ppGpp
                     synthetase/guanosine-3',5'-bis(diphosphate)
                     3'-pyrophosphohydrolase"
                     /protein_id="HET2612650.1"
                     /translation="MPKEVNLTGEEVVALTKEYLTEEDVHFVHKALVYAVECHSGQYR
                     KSGEPYIIHPIQVAGILAKLKLDAVTVACGFLHDVVEDTDATLDDLEREFGPDVRMIV
                     DGVTKLGKVEYKSIEEQLAENHRKMLMAMSEDIRVILVKLSDRLHNMRTLKHLRKDKQ
                     ERISKETMEIYAPLAHRLGISSVKWELEDLSFRYLNPTEFYKITHMMKEKRREREALV
                     DEVVTKLEEYTTERHLKGKIYGRPKHIYSIFRKMQDKRKRFEEIYDLIAIRCILDTQS
                     DVYAMLGYVHEFWKPMPGRFKDYIANRKANGYQSIHTTVYGPKGPIEFQIRTKEMHEV
                     AEYGVAAHWAYKKGIKGQVNSKESAIGMNWIKEMMELQDQADDAKEFVDSVKENYLAE
                     EIYVFTPDGAVRSLPKDSGPIDFAYEIHTKVGEKATGAKVNGRMVPLTTKLKTGDQVE
                     IIANPNSFGPSRDWLNMVKTSKARNKIRQFFKNQDKELSVNKGREMLMAQFQENGYVA
                     NKFMDKRHMDQVLQKTSYKTEDSLFAAIGFGEIGAITVFNRLTEKERREEERAKAKAE
                     AEELVKGGEVKVENKETLKVKHEGGVVIEGASGLLVRIAKCCNPVPGDDIVGYITKGR
                     GVAIHRVDCMNLRAQENYEQRLLDVEWEDQYSSSNKEYMAHIDIYGLNRTGLLNDVLQ
                     VLSNTTKNISTVNAQPTKDMKFANIHVSFGIANLSTLTTVVDKIKSVPEVYSVKRTNG
                     "
     gene            3790..4032
                     /locus_tag="VQ543_001991"
     CDS             3790..4032
                     /locus_tag="VQ543_001991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2612651.1"
                     /translation="MTRFEEIFEEYKNPQDTFFYPLVYKENTYEKTAISIFALLMLGV
                     CCLFLFSQQSYKKLVQYYANDQNLPSRITYSEYSDK"
     gene            4372..5001
                     /locus_tag="VQ543_001992"
     CDS             4372..5001
                     /locus_tag="VQ543_001992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000690864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HET2612652.1"
                     /translation="MKIHKTVNPVAYENTYYLEGEKHLIVVDPGSHWEAIRQTIEKIN
                     KPICAILLTHAHYDHIMSLDLVRETFGNPPVYIAESEASWLYTPVDNLSGLPRHDDMA
                     DVVTKPAEHTFVFHEEYQLEEFRFKVLPTPGHSIGGVSLVFPDAHLVLTGDALFRETI
                     GRTDLPTGSMEQLLHSIQTQLFTLPNYDVYPGHGPATTIAHEKAFNPFF"
     gene            complement(5124..7016)
                     /gene="pepO"
                     /locus_tag="VQ543_001993"
     CDS             complement(5124..7016)
                     /gene="pepO"
                     /locus_tag="VQ543_001993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endopeptidase PepO"
                     /protein_id="HET2612653.1"
                     /translation="MTRYQDDFYDAINGEWQQTAEIPADKSQTGGFVDLDQEIEDLML
                     ATTDKWLAGEEVPEDAILENFVKYHRLVRDFDKREADGITPVLPLLKEFQELETFADF
                     TAKLAEFELAGKPNFLPFGVSPDFMDARINVLWASAPSTILPDTTYYAEEHPQREELL
                     TLWKESSANLLKAYDFSDEEIEDLLEKRLELDRRVAAVVLSNEESSEYAKLYHPYSYE
                     DFKKFAPALPLDDFFKAVIGQLPDKVIVDEERFWQAAEQFYSEEAWSLLKATLILSVV
                     NLSTSYLTEDIRVLSGAYSRALSGVPEAKDKVKAAYHLAQEPFKQALGLWYAREKFSP
                     EAKADVEKKVATMIDVYKERLLKNDWLTPETCKQAIVKLNVIKPYIGYPEELPARYKD
                     KVVNETASLFENALAFARVEIKHSWSKWNQPVDYKEWGMPAHMVNAYYNPQKNLIVFP
                     AAILQAPFYDLHQSSSANYGGIGAVIAHEISHAFDTNGASFDENGSLKDWWTESDYAA
                     FKEKTQKVIDQFDGQDSYGATINGKLTVSENVADLGGIAAALEAAKREADFSAEEFFY
                     NFGRIWRMKGRPEFMKLLASVDVHAPAKLRVNVQVPNFDDFFTTYDVKEGDGMWRSPE
                     ERVIIW"
BASE COUNT         1985 a         1681 c         1378 g         2176 t
ORIGIN      
        1 ttatcatttt atgacaaaca tactatcgtt aaatgctgat ttaatcgaaa ttttgagtta
       61 taaactcctc agtttcgaac tcaaaattag ccgtgcagga taggataccc ttcataaact
      121 tatataacta ctttaatacc ttaaaaagct aataaaataa ggaatatcta agcaatatac
      181 attctaaaat acctgtacgg gagtgtctct aaagaaaagg aggttttagc atgaaaaaaa
      241 tcatcttcat caaaaccatt caactccttg tcattgatgg aatcatgctg gcatttttga
      301 catttaaaag gggggcttac ttgggactgg attttgattt atagtggttg gctcattttc
      361 tttcatcctg tgctattgac ctatctttca aaccaacttt gtgaccactt tagtcaactc
      421 tattcccaga ttagaccgag attctggcgt tttgctttac aaattctcct atgggatagc
      481 ctgatgattc tctccttggt gtctttaagt gatattccac ttttccttca gggaactctc
      541 ctcatcctag gacatctcat cccttcctat cgcatctgcc aaagcctgaa aagagacttc
      601 ccccaagcat atcaagaacc gatttctttt tggagtattt tatgatcgat gagaaagacc
      661 aagccgactg ggcttggtct ttcttatctc tttttagtat ctaggataat ggtaacaggt
      721 ccgttattaa ccagctcaac ctgcatatct gctccaaaga tacctgtctg aacgggcact
      781 tcttgcgcta atttttgatt gaaagcatca tagaagtctg atgccatatc aggtttagct
      841 gcccctgtaa aggctggacg attgcctttc ttagtatccg caaagagggt aaactgagaa
      901 atagagagga tttctccttc aatatctttg acagacaggt tcatcttgcc ttctgcgtct
      961 gaaaaaatcc gcatattgac cagttttctc acagcatagt ccaaatcttc ctcttggtcc
     1021 tctggtccaa caccaaccag caataaaagt ccctgattga tttttccctg aatctggcct
     1081 tctatactca cttgggcttt tttaacccgt tggataatga ttttcataat agcctttcta
     1141 gtaagagcta ggacaactag ccgttggtcc gtttgacaga gtaaacttct ggcacactct
     1201 taattttatc gacaaccgtg gtcagtgtag agaggttggc aataccgaag gacacatgga
     1261 tattagcaaa cttcatatcc ttggttggtt gggcattgac cgttgaaata ttcttggttg
     1321 tatttgaaag aacttgcagt acatcgttca acagtcctgt acggttgaga ccgtagatat
     1381 cgatatgggc catatactcc ttatttgagc tagagtactg gtcttcccat tccacatcaa
     1441 ggagacgttg ctcgtagttt tcttgggcac gcaggttcat acagtccaca cggtgaatag
     1501 ccacaccacg acccttggta atgtagccaa caatatcgtc accaggcacg gggttacaac
     1561 acttagcaat ccgcactagg agaccagaag caccttcaat aaccactccc ccctcatgct
     1621 tgaccttgag agtttcttta ttttcaacct tgacctcgcc acctttgaca agctcctctg
     1681 cctcagcctt ggccttggca cgctcttcct cacggcgttc cttttcagtc agacggttaa
     1741 agacggtaat cgcaccgatt tccccaaaac caatggccgc aaagagggag tcttctgtct
     1801 tgtaactggt cttttgcaga acttgatcca tgtggcgctt gtccataaat ttatttgcca
     1861 catagccatt ttcttggaac tgagccatca gcatctcacg acccttgttg acagacaatt
     1921 ccttatcttg gtttttaaag aactggcgaa tcttattgcg cgccttgcta gtcttgacca
     1981 tattgagcca gtcacggcta ggtccaaagg agttcgggtt ggcgataatt tcaacctgat
     2041 cccctgtctt taacttggtt gtcagtggaa ccatgcggcc attgaccttg gcaccagttg
     2101 ctttttcacc gaccttggta tggatttcgt aggcaaaatc aatcggtcct gaatctttgg
     2161 gaagagaacg gacagctcca tctggggtaa aaacgtaaat ctcctcagcc agatagtttt
     2221 ccttaacaga gtccacaaat tccttagcat catcagcctg gtcttggagc tccatcatct
     2281 ccttgatcca gttcattcca atagctgatt ccttgctgtt aacttgcccc tttatacctt
     2341 tcttataagc ccagtgagcc gcaaccccgt actcagccac ctcgtgcatt tccttggttc
     2401 gaatctggaa ttcaatcggc ccttttggtc cataaacagt cgtatggata gactgataac
     2461 cattagcctt gcggttggca atatagtctt tgaagcgacc tggcatcggt ttccaaaatt
     2521 catgcacgta accaagcatg gcataaacat cactttgggt atctaaaata caacgaatag
     2581 caatcagatc atagatttcc tcaaaccgtt ttctcttgtc ctgcattttg cggaaaattg
     2641 agtaaatatg cttgggacga ccataaatct tccctttcaa gtgacgttct gtcgtatact
     2701 cctctaattt tgtgactacc tcatccacca aggcctcacg ctccctgcgc ttttccttca
     2761 tcatatgggt aatcttgtaa aactccgttg gattgagata acggaaagac aagtcttcta
     2821 attcccattt gacactggaa atccccaaac gatgggcaag cggggcatag atttccatgg
     2881 tttctttgga aatacgctcc tgcttgtctt ttcgaagatg tttcagggtc cgcatattgt
     2941 gcaagcggtc agacagtttg accaaaataa cgcggatgtc ctcagacatg gccatgagca
     3001 tcttgcgatg attttccgct aattgctcct cgatcgattt gtactcgacc ttgccaagct
     3061 tggtaactcc gtcaacaatc atccgcacat caggaccaaa ctctctttcc aaatcgtcca
     3121 aagtcgcatc tgtatcttcc accacatcat gcaagaatcc acaagctact gttacagcat
     3181 ccagctttag cttagctaaa atacctgcca cttggatagg gtgaatgata taaggctcgc
     3241 ctgatttgcg atattgacca ctgtggcatt caacagcata gaccaaggcc ttatggacaa
     3301 aatgaacatc ctcttccgtt aaatattctt tggttaaagc gacaacttct tcgcctgtta
     3361 aattcacttc tttcggcatc tctactctcc aattcttcct accattttat cactttttta
     3421 agaatatgaa aactagattg gaacagaata agaaaaaaat aattcaaaat tgcttgataa
     3481 ttctgaatta ttggcccata atatactacg aagttagatt ttaaacttag gtgatagaag
     3541 gagagataga agaacggaaa ccatattgta acccaaagac tttctgattt ccccaattcc
     3601 attgaagata cgaaagataa acggtggaac tcgtatcaca tacactggta ccttgactgg
     3661 attttggaat taatactcaa tgaaaatcaa agagcaaact aggaaactag ccacaggttg
     3721 ctcaaagcac tgctttgagg ttgtagataa gactgacaaa gtcagtcaca tatatacggc
     3781 aaggcgacgt tgacgcggtt tgaagagatt tttgaagagt ataaaaatcc tcaagatact
     3841 ttcttctatc ctttagttta taaggagaat acctatgaaa aaactgctat ttctatcttt
     3901 gctctcctaa tgttaggagt ttgctgcctg ttcctattca gccagcaaag ctataaaaaa
     3961 ctcgttcaat actatgctaa cgaccagaac ctgcccagta ggataactta tagtgaatat
     4021 agcgacaaat gagaagccaa ctacggtagc actctaaaca tcacgtctat caaacaagct
     4081 aatgacggag tttatgcaac ctatgaaggg caattgacac ctttccaata ttgataaatt
     4141 gataaccagc ctgtcttcat ctagtcatgc tggtttttaa gttcatttta aatccttacc
     4201 tattctccct aactgtgcta tacttaattt atactcaatg aaaatcaaag agcaaactag
     4261 aaagctagcc gcaggctgtt caaagcactg ctttgaggtt gcagataaag ttgacgcggt
     4321 ttgaagagat tttcgaagag tattagtaca ttctttgaga ttggagttag tatgaaaatc
     4381 cataaaaccg tgaatcctgt tgcctatgaa aatacctatt atctagaagg cgaaaagcac
     4441 ctcatcgtcg tcgatcctgg tagtcattgg gaagccattc gtcagacaat cgagaagatc
     4501 aacaaaccga tctgtgctat tctcttgacc cacgcccatt atgaccatat catgagtctg
     4561 gacttggttc gcgagacgtt tggcaatcct cctgtctata tcgcagagag cgaagccagc
     4621 tggctctaca ctcctgtcga taatctctcc ggtctccctc gccacgatga tatggcagat
     4681 gtggtcacaa aacctgcaga acacaccttt gtctttcacg aagaatacca actagaggaa
     4741 tttcgtttta aggttctacc gaccccaggg cactctatcg gtggtgtttc cctagtcttt
     4801 cctgatgctc acctagtctt gacgggagat gctctattcc gcgaaactat cggacggacc
     4861 gaccttccga ctggtagcat ggagcaactc cttcatagta tccagaccca actcttcacc
     4921 ctaccaaact acgatgtcta tccaggacat ggtccagcta ctactatcgc tcacgaaaag
     4981 gccttcaatc cctttttcta gcaagatgat gacaatcgaa atttaagtaa actatccagc
     5041 aaatctttct attacaaaag gcatcctatc aaggttttca cacgtgattg gatgcctttt
     5101 ttctgatgac tagatttttt gtattaccaa ataatcacgc gctcctctgg tgaacgccac
     5161 attccgtctc cttctttgac atcataggtt gtaaagaaat cgtcgaagtt tggtacttgc
     5221 acattgacac ggagtttggc tggtgcgtgc acatcgacgc tagccaaaag tttcataaat
     5281 tctggtcgac ctttcatgcg ccagatgcga ccgaagttgt agaagaactc ttctgctgag
     5341 aagtctgctt ctctcttagc tgcttcaagc gctgctgcga ttcctcccaa gtcagccacg
     5401 ttttctgata cagtcaattt accgttaatg gttgctccat aagaatcctg tccatcaaat
     5461 tggtcaatga ctttttgtgt tttctccttg aaggcagcat agtcgctctc tgtccaccaa
     5521 tccttgaggc taccattttc gtcaaaggaa gccccgttag tatcaaaggc gtgggaaatt
     5581 tcatgggcaa tcactgcccc aataccaccg tagttagcag aagatgactg atgcaagtca
     5641 tagaaaggcg cctgtaaaat ggccgctgga aagacaatca ggttcttctg aggattgtag
     5701 taggcattga ccatatgagc aggcatgccc cattccttat agtctacagg ctggttccac
     5761 ttactccaac tgtgcttgat ttccacacgc gcaaaggcta gagcattctc aaaaagactg
     5821 gcagtttcat tcactacctt atccttgtaa cgtgcaggca attcttctgg atagccaata
     5881 taaggtttga tcacattgag cttcacgata gcctgtttac aggtttctgg agtgagccag
     5941 tcattcttaa gcagacgctc cttatagaca tcaatcatgg ttgccacttt tttctccaca
     6001 tccgccttgg cttctggaga gaacttctca cgggcgtacc aaagccccag ggcttgcttg
     6061 aaaggttcct gtgctagatg ataagctgct ttgaccttat cttttgcctc tggaactcca
     6121 gaaagggcac ggctgtaggc accagacaaa acacggatat cctctgttaa atagctggtt
     6181 gaaagattga caacactcaa aatcaaggtt gctttaagga gagaccaggc ttcctcactg
     6241 taaaattgct ctgctgcttg ccagaaacgt tcctcgtcta caataacctt gtctggtaat
     6301 tgcccaataa ctgctttgaa gaagtcatcc aaaggtaggg caggcgcgaa tttcttgaaa
     6361 tcttcgtaag aatatggatg atagagttta gcatattctg aactttcttc attagagagc
     6421 accactgccg caactcggcg gtccaattca agtctttttt ctagcaagtc ttcaatttct
     6481 tcatcagaga aatcataagc cttgaggaga tttgcgctgc tttctttcca aagagtcaag
     6541 agctcttcgc gctgaggatg ttcttctgca tagtaggtcg tatctggcaa gattgtgctt
     6601 ggagcgctag cccatagaac attgattcta gcatccataa agtctggcga tacaccaaaa
     6661 ggaaggaagt ttggttttcc tgcaagctca aactctgcta gtttagctgt aaaatccgca
     6721 aaagtttcca attcttggaa ttctttaagg agtggtaaga caggtgtgat accgtcagct
     6781 tctctcttgt caaaatcacg aactaggcgg tggtatttga caaagttttc caagatagca
     6841 tcctcaggca cttcttcacc tgctaaccac ttgtctgttg tcgccagcat caggtcttca
     6901 atttcctggt ctaaatcaac aaaacctcct gtttgagact tatctgctgg gatttcagct
     6961 gtctgttgcc attctccatt gatagcatca taaaaatcat cttgataacg tgtcatcttg
     7021 ttctcgcttt catttgtatt tgcatttatc ttaacaaaaa tcactaggga atgcaattaa
     7081 taaccattta actattattt tttagctatt ataaaaaacc tttccatgat aaaacgcata
     7141 attccaagtt ttttacactt gatactatgc gttttataat ttagaaattt atcctgaaag
     7201 ttatctttag aatctatttt
//
LOCUS       DAVBEO010000075         7162 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 009
            SAMEA1678075-rid20185393.denovo.075, whole genome shotgun sequence.
ACCESSION   DAVBEO010000075 DAVBEO010000000
VERSION     DAVBEO010000075.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678075
            Sequence Read Archive: ERR226392
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7162)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7162)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980207.1
            Genome Coverage       :: 150x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:50:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 72 of 147
            Pseudo Genes (incomplete)         :: 72 of 147
            Pseudo Genes (internal stop)      :: 42 of 147
            Pseudo Genes (multiple problems)  :: 32 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7162
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678075-rid20185393.denovo.075"
                     /strain="KS 009"
                     /db_xref="taxon:1313"
     gene            complement(741..1001)
                     /locus_tag="VQ543_001994"
     CDS             complement(741..1001)
                     /locus_tag="VQ543_001994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2612654.1"
                     /translation="MRERSATGAQGLSKSIKKHLNDLTRLTASLLGDEKLSAITSSSA
                     VKADIHRFVIELEPVKSTILQNDDISLDQNEIFEILKNFLDG"
     gene            complement(1060..1611)
                     /locus_tag="VQ543_001995"
     CDS             complement(1060..1611)
                     /locus_tag="VQ543_001995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001111259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2612655.1"
                     /translation="MPANTKVIFQEMFADFQNYYVLIGGTATSIVLDSQGFKSRTTKD
                     YDMVIIYEVKNKEFYTTLNHFLELGEYQGSQKDEKAQLFRFTTTNPEFPSMIELFSIL
                     PEYPLKKDGREIPLHFDQDASLSALLLDEDYYNILVHEKETIQGYSVLSNCGLYSSKI
                     SSNHVSFHLQPQNSVLSSLQLAS"
     gene            complement(1601..1798)
                     /locus_tag="VQ543_001996"
     CDS             complement(1601..1798)
                     /locus_tag="VQ543_001996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000890145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2612656.1"
                     /translation="MLEIWKYRPFVSEFWNDFKNNHDKQFVDPISLYLTLKDDDDPRI
                     EEESEALENMILQYLGEDDAS"
     gene            complement(1802..2386)
                     /locus_tag="VQ543_001997"
     CDS             complement(1802..2386)
                     /locus_tag="VQ543_001997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001101186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2612657.1"
                     /translation="MNVKKIMSIFQSFYVDVSIEELTLTLPISFVKRFEYTQMTFHKE
                     SFLLIKEKRRGSLSSFVTQARTMGEKANMDVVLVFSKLSDSEKKQLLQARVPFVDFKG
                     NLFFPPLGLVLNANDTEIPKELTPSEQLTWIAFLLPDGDIKQIKSVSNLLYGGAYALS
                     HSTFLAETDENTSYVIWQRKFNQLSLPLSQHVLK"
     gene            complement(2794..3219)
                     /locus_tag="VQ543_001998"
     CDS             complement(2794..3219)
                     /locus_tag="VQ543_001998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000204059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2612658.1"
                     /translation="MTSRVFIDADCISAFLWVGTEHLLEKLYSGKIVIPQEVYDEINI
                     PTIPHLKSRIDQLVTKGSAEIVSIDIGTEEYALYRDLTRNYDSNKIIGKGEATSIFLA
                     KKHNGILGSNNLRDVKPYVEEFSLEHMTTGDILIEAFKA"
     gene            complement(3212..3706)
                     /locus_tag="VQ543_001999"
     CDS             complement(3212..3706)
                     /locus_tag="VQ543_001999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004236771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2612659.1"
                     /translation="MKKSSVSLILIGEGDETERKADQFASYFLIFPSSLYRMVEEIRE
                     NANRTHLEVEDIIKLGQFYGISHKAMLYRLRNDGYLDAEEIKNMDISVIETASRLGYD
                     TSLYRPLSESKKEMVLGHYIKSTEQLLENNRISQGKYEELLLDAFRYDIVYGLDEEGE
                     LSFD"
     gene            complement(3752..3958)
                     /locus_tag="VQ543_002000"
     CDS             complement(3752..3958)
                     /locus_tag="VQ543_002000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000366086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2612660.1"
                     /translation="MDLSNKASNLRKKLGADGESPIDIFKLVQKIENLTLVFYGLGKN
                     ISGVCYKGTQFSLIAVNSDMPLGR"
     gene            complement(3945..4106)
                     /locus_tag="VQ543_002001"
     CDS             complement(3945..4106)
                     /locus_tag="VQ543_002001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000289348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET2612661.1"
                     /translation="MNMINVCDVGKRIKELRISSNLTQDKIAEYLSLNQSMIAKMEKG
                     ERNITNGFK"
     gene            complement(4471..5427)
                     /gene="lytA"
                     /locus_tag="VQ543_002002"
     CDS             complement(4471..5427)
                     /gene="lytA"
                     /locus_tag="VQ543_002002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase LytA"
                     /protein_id="HET2612662.1"
                     /translation="MEINVSKLRTDLPQVGVQPYRQVHAHSTGNPHSTVQNEADYHWR
                     KDPELGFFSHIVGNGCIMQVGPVDNGAWDVGGGWNAETYAAVELIESHSTKEEFMTDY
                     RLYIELLRNLADEAGLPKTLDTGSLAGIKTHEYCTNNQPNNHSDHVDPYPYLAKWGIS
                     REQFKHDIENGLTIETGWQKNDTGYWYVHSDGSYPKDKFEKINGTWYYFDSSGYMLAD
                     RWRKHTDGNWYWFDNSGEMATGWKKIADKWYYFNEEGAMKTGWVKYKDTWYYLDAKEG
                     AMVSNAFIQSADGTGWYYLKPDGTLADKPDFTVEPEGLITVK"
     gene            complement(5803..7155)
                     /locus_tag="VQ543_002003"
     CDS             complement(5803..7155)
                     /locus_tag="VQ543_002003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000364185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HET2612663.1"
                     /translation="MDLIHGPILPSLLSFTFPILLSNIFQQLYNTADVLIVGRFLGQE
                     SLAAVGATTAIFDLIVGFTLGVGNGMGIVIARYYGARNFTKIKEAVAATWILGALLSI
                     LVMLLGFLGLYHLLQYLDTPAEILPQSYQYISMIVTCVGVSFAYNLFAGLLRSIGDSL
                     AALGFLIFSALVNVVLDLYFITQLHLGVQSAGLATIISQGLSAVLCFYYIRKSVPELL
                     PQFKHFKWDKSLYADLLEQGLAMGLMSSIVSIGSVILQFSVNTFGAVIISAQTAARRI
                     MTFALLPMTAISASMTTFASQNLGAKRPDRIVQGLRIGSRLSISWAVFVCIFLFFASP
                     ALVSFLASSTDGYLIENGSLYLQISSAFYPILSLLLIYRNCLQGLGQKILPLVSSFIE
                     LIGKIVFVVLIIPWAGYKGVILCEPLIWVAMTVQLYFSLFRHPLIKEGKAILATKVQS
                     "
BASE COUNT         2298 a         1486 c         1132 g         2246 t
ORIGIN      
        1 tggtttcgca ggaagtctat tatatatgca cagacatatg aaatcttttt gagacagcag
       61 ttatgatata tttatccatt cacaacatct tctgtactaa tactacaata ttggtacatt
      121 ttgattacac aatcgtttca aaaaatatga tggaagcctg agtattttat agtaattccc
      181 ttcctatcaa ctagatcaac cagttgagtg ttgaatgttg aaacacccta gcctcagcaa
      241 aggactatga tcagcatttc ctagccaata ggacgctcca aatcacctat tctaagtcca
      301 tcactagctt ggtcagtaag atacagactg caaggcgaga ctgacgtggt tgatgagatt
      361 ttggaagagt attacaatca tagattcacc agtagacttg accgcagatt taactatagt
      421 agattgaaac tagaatagta catctctgct tctaaaacat tgttagaaat cgatttgact
      481 gtcctgatca atttgtcctg ttctcgtttc atttcactat actaaaaaac cacctgaaac
      541 aaatcaagtg actagaggat aaaaacaaag actaggcaaa aagttttgaa aagcaaaaaa
      601 cgcataatat caggtcttga aaaaccttga tactatacgt ttgattgtgg gaagattgac
      661 ttcattttct cctgaaattg aagttttttc tagtttccag atatagacga attcaatata
      721 gccatctcgc tacaattatt ttaaccatcg agaaaatttt tcagaatttc aaaaatttca
      781 ttttgatcca atgaaatgtc atcattttga agaatagttg acttcacagg ctctaattct
      841 atcacaaagc ggtgtatgtc tgcttttacc gcactacttg atgttatagc cgataacttt
      901 tcatctccta gcaaggaagc tgtcaaacgg gtaaggtcat tcaaatgctt tttaatggac
      961 ttacttaaac cttgagcacc tgtagcagag cgttccctca tatccagcca agctttagcc
     1021 ttaaaaataa ttaatactca atgaaaatca aagagcaaac taggaagcta gctgcaggct
     1081 gctcaaaaca ctgttttgag gttgtagatg gaagctgacg tggtttgaag agattttcga
     1141 agagtataaa ccacaattac tcaataccga atacccctga atggtttctt tttcatgcac
     1201 caatatatta taataatctt catccaataa taaggctgat aaactagcat cttggtcaaa
     1261 atgtaaggga atttctcgac cgtccttctt taatggatat tctggtaaga tactaaatag
     1321 ttcaatcata gaaggaaact caggattagt tgttgtaaat cgaaaaagct gcgctttctc
     1381 atctttctga cttccttgat actctcccaa ttctaaaaaa tgattcaagg tagtataaaa
     1441 ttccttattt tttacttcat aaatgatgac catatcataa tcttttgttg tgcgactttt
     1501 aaatccttgc gaatccaata cgatagaggt agcagttccc ccaatcagaa cataatagtt
     1561 ctgaaaatcc gcaaacattt cttgaaaaat aactttcgta ttagctggca tcatcttctc
     1621 ccagatactg taatatcata ttttctagtg cttcactctc ttcctctata cgtgggtcat
     1681 catcatcttt taaggtcaaa taaagagaaa tcggatctac aaattgttta tcatgattat
     1741 ttttaaaatc attccaaaac tcagatacaa aaggacgata tttccatatc tctagcatct
     1801 ttcattttaa aacatgctga gaaagtggca aggataactg attgaatttt ctctgccata
     1861 tgacatagct agtattttca tccgtttcag ctaaaaaagt tgaatgcgac aaagcataag
     1921 caccaccata tagaaggtta gaaacagatt ttatctgctt tatatcgcca tctggcaata
     1981 aaaaggcaat ccacgttaat tgttcgctag gtgttaattc cttagggatt tcagtatcat
     2041 tcgcattgag tactagtccc aatggaggga agaagaggtt tcccttaaag tctacaaacg
     2101 gaactctagc ttgaagtaat tgcttttttt cactgtctga taacttcgaa aacaccaaaa
     2161 caacatccat attggctttt tcacccatag tgcgagcctg agtaacaaat gaactcaaac
     2221 tcccccttct cttttcttta atcaataaaa atgattcctt atgaaaagtc atttgagtat
     2281 actcaaacct ttttacaaaa ctgattggta aagtcaaagt cagttcctca atactgacat
     2341 caacataaaa ggattgaaaa attgacatta tctttttgac attcatgttt tttccttatt
     2401 ctatcatttt tattatattt tatcattcgg tataataaaa tataagtttt ttgataaaat
     2461 aaccaaaaac tactcgctat cccctctcac attaccctac atatcgtttg acatgcgact
     2521 gatagttcag gaaaacttca aggagaactt ttctctcatc cactatgcag gacttactat
     2581 ttcacttcta ctcctatagg ctcaatttga cacttttctt tttcgaattg ctcatatgcc
     2641 tcctgaatag tgagttcgat ttatccaaat ttatttttgt ctattttgat gaatacttcc
     2701 acgaagatag tctgaaaatg aatttgcacc aattttcctt ctctttttaa gcatattatt
     2761 ccagatatga ttgccctctt gttcagtaat aaattacgct ttaaacgctt caatcagtat
     2821 atctcctgtt gtcatatgtt ctaaagaaaa ttcttctaca tatggtttaa catctcttag
     2881 gttattactt cctaatatcc cattatgctt tttcgctaag aaaatagaag tcgcttctcc
     2941 cttaccaata atcttgttac tatcataatt tcttgttaaa tctctatata atgcgtattc
     3001 ttcagttcca atgtctatgc tcacaatctc agctgaaccc ttagttacca actggtctat
     3061 cctagatttt aaatggggaa ttgtaggtat attgatttca tcatacacct cttgtggaat
     3121 aacaatttta cccgaataga gcttttctaa aagatgttca gtgccaaccc ataaaaatgc
     3181 tgaaatacaa tctgcatcaa taaatacacg actagtcaaa cgacaactcc ccctcttcat
     3241 ctagcccata tacaatatca tatctgaaag catctagtaa cagttcctca tacttccctt
     3301 gcgaaattct gttattttct aaaagttgtt cagtcgattt aatatagtgc cctaatacca
     3361 tttccttttt actttctgac aaaggacgat ataaacttgt atcatagcct aatcttgaag
     3421 ctgtctctat aacactaata tccatatttt taatttcttc tgcatcaagg tatccatcat
     3481 ttctcaatct atataacata gctttatgac tgataccata aaactgaccc aattttataa
     3541 tatcttctac ttcaagatga gttctattgg cattttctct gatttcctca accatcctat
     3601 acagtgaaga tgggaaaatt aaaaaataag aagcaaactg atccgctttt ctttcagttt
     3661 catctccttc accaatcaag ataagactga ctgaactctt cttcacctca tcataataaa
     3721 gatgatacag tccatgtgct aaagaaaatc tttaccttcc taatggcatg tctgaattga
     3781 ctgcaatgag actgaactga gttcctttat aacagactcc gctaatattc tttccgagtc
     3841 cataaaatac cagcgtcaaa ttttctatct tttgtaccaa tttaaaaata tctatcggcg
     3901 attcaccatc agctcccaac ttttttctaa gatttgaagc tttattactt aaatccattc
     3961 gtgatattcc tttcaccttt ttccattttg gcaatcatgc tttgattcaa agacaaatac
     4021 tcagcaatct tatcttgagt aagatttgaa gatattctaa gttcttttat tctttttcca
     4081 acatcacata catttatcat attcatacac ctctcataaa aagaatagca cattcttgtc
     4141 ataatttttt aaataaaaaa attatgacaa aacaaggaag caatttattg atgctactta
     4201 aaaatctaaa attgatgata ttaaacctat ttgatgagtt cctatcaaaa atcgtatctt
     4261 caacctcaaa acagtactta aagctatccg actcggttta cattgtcaaa tttagatttt
     4321 atttgagcat aactttctag tttgcttttt gatttttgtt taatatagta acaaaaattg
     4381 aaggaaatat ctccacaaga aaacgcatac tattaagctt tttcaagacc taataatatg
     4441 cgctgttctg atttgaaaga cattccatta ttattttact gtaatcaagc cttcaggctc
     4501 tactgtgaag tctggcttgt ctgccagtgt tccgtctggt ttgaggtagt accagcctgt
     4561 tccgtccgct gactggataa aggcatttga taccatggcg ccttctttag cgtctaagta
     4621 gtaccaagtg tccttgtact tgacccagcc tgtcttcatg gcaccttctt cgttgaaata
     4681 gtaccactta tcagcgattt tcttccagcc tgtagccatt tcgcctgagt tgtcgaacca
     4741 gtaccagttg ccgtctgtgt gcttcctcca gcggtctgca agcatatagc ctgaactgtc
     4801 aaagtagtac caagtgccat tgattttctc aaacttgtct tttggataag agccgtctga
     4861 atgtacgtac cagtagccag tgtcattctt ctgccagcct gtttcaatcg tcaagccgtt
     4921 ctcaatatca tgcttaaact gctcacggct aatgccccat ttagcaagat atggataagg
     4981 gtcaacgtgg tctgagtggt tgtttggttg gttattcgtg caatactcgt gcgttttaat
     5041 tccagctaaa ctccctgtat caagcgtttt cggcaaacct gcttcatctg ctagattgcg
     5101 taagagttcg atataaaggc ggtagtccgt catgaactct tctttggttg aatggctttc
     5161 aatcagttca accgctgcat aggtctcagc attccaaccg cccccaacgt cccaggcacc
     5221 attatcaaca ggtcctacct gcatgatgca accgttccca acaatgtgcg agaaaaaacc
     5281 taattctggg tctttccgcc agtgataatc cgcttcattc tgtacggttg aatgcggatt
     5341 cccagttgag tgtgcgtgta cttgcctata tggttgcacg ccgacttgag gcaaatctgt
     5401 tcttaattta ctcacattaa tttccatatt ctactcctta tcaattaaaa caactcattt
     5461 tttacaatcc agaaccagaa actcctttat ttctacctta caaagaagac aatcttagtc
     5521 acgattaagc ttgtagatag aacctcaaaa cgcactattt tgacactgta aataggactg
     5581 acaaggtctg cattctatct acaataacac cccagactaa aaagcttttc aaaagtatat
     5641 ttttacagtc tctatatgtc cttttcataa atactatact ttattatatc acataaaaga
     5701 agtcaaaagt ctgttaaact attttcaaca ccaaactaaa gaagagaaca caagtttttt
     5761 cgatgttcac tagaggaaat ggattttatt cagtaaatcc aactaggatt gcactttggt
     5821 tgccaaaatt gcctttcctt cttttatcaa gggatgacgg aatagtgaga agtacagttg
     5881 aactgtcatg gcaacccaga taagaggttc acaaaggata acacccttat atcctgccca
     5941 aggaataatc aaaaccacaa aaacgatttt tccgattagt tcaataaagc tagaaactag
     6001 aggaaggatc ttctgcccca agccctgcaa gcaattgcga taaatcaaca agaggctcaa
     6061 aatgggataa aaggctgaac tgatttgcag atagagactt ccattttcta tcaagtaacc
     6121 atctgtcgaa ctagccaaga aggaaaccaa ggctggactg gcaaaaaaga ggaaaataca
     6181 aacaaaaact gcccaggata tacttaaacg actgccgatt cgaagacctt gaacaatgcg
     6241 gtcaggtcgc ttagctccta gattctgaga agcaaaggtc gtcattgatg cagaaatagc
     6301 ggtcatagga agaagggcaa aggtcataat gcgtcgagct gccgtctggg cactaataat
     6361 cactgcacca aatgtattaa cagaaaactg taaaatcaca ctgccgatag atacaattga
     6421 actcatcaag cccatagcca aaccttgctc caagagatcc gcgtacaagc ttttgtccca
     6481 tttgaaatgt ttaaactgtg gcaagagttc tggcacactt ttacgaatat aataaaagca
     6541 gagaaccgct gataaacctt gcgaaataat ggtagcaagt cctgcggatt gaactcccag
     6601 atgcaattgc gtaataaaat agagatccag aaccacatta accaaggcag agaaaatcag
     6661 aaatcccagg gctgctagac tgtcaccaat agaccgcaac aagcctgcaa aaagattata
     6721 agcaaagctg acacctacac aggtcacaat catagaaata tattgataag attgaggaag
     6781 aatttctgca ggagtatcta agtattgcaa gagatgatac aagccaagaa agcccagcaa
     6841 cataactaga atgctcaaaa gagcacctaa aatccaagta gctgctactg cttccttgat
     6901 tttagtgaaa ttccgagccc cataataacg agcaatgaca atccccatgc cattgccaac
     6961 accaagtgta aaacctacaa tcaggtcaaa aatcgctgtc gtcgctccta ctgcagccaa
     7021 ggattcttga ccaagaaatc gtccaacaat caagacatca gcagtgttat agagctgttg
     7081 aaaaatattt gatagcaaaa ttggaaaggt gaagcttaag agcgagggaa gaatcggacc
     7141 atgtatcagg tccactgttc gt
//
LOCUS       DAVBEO010000076         6880 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 009
            SAMEA1678075-rid20185393.denovo.076, whole genome shotgun sequence.
ACCESSION   DAVBEO010000076 DAVBEO010000000
VERSION     DAVBEO010000076.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678075
            Sequence Read Archive: ERR226392
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6880)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6880)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980207.1
            Genome Coverage       :: 150x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:50:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 72 of 147
            Pseudo Genes (incomplete)         :: 72 of 147
            Pseudo Genes (internal stop)      :: 42 of 147
            Pseudo Genes (multiple problems)  :: 32 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6880
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678075-rid20185393.denovo.076"
                     /strain="KS 009"
                     /db_xref="taxon:1313"
     gene            <1..307
                     /locus_tag="VQ543_002004"
     CDS             <1..307
                     /locus_tag="VQ543_002004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET2612664.1"
                     /translation="APMTYEETMTSDFFEVWFQKFFLPTLTTPSVIIMDNVRFHRMGK
                     LELLCEEFGHKLLPLPPYSPEYNPIEKTWVHIKKHLKKVLPSCNTFYEALLSCSCFN"
     gene            368..1330
                     /locus_tag="VQ543_002005"
     CDS             368..1330
                     /locus_tag="VQ543_002005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HET2612665.1"
                     /translation="MNMSNITIDGQEMDLSQTMPSYAQVVSLYDDTSISVSSNETDKV
                     LAGSLYTDTNEQGLTIPSSLLKNWNEQTGKNLTANDLIGKSVSASIVESAAETSKIAQ
                     FQTKIVRVINDEDDMEDSNSFMLSHQMETILKEAGFTKAVSYFILELKDPSQTKVVTE
                     ELQKNKKYTVLSQQRVLDIVIIFIRVIQGLLIVLSSQAIVVAAVMIGIIIYINIMQRS
                     KEIGVMKAVGYQNRDVKGIFIYEAIWIVGIALLLAFLVAQGVGSLANAIVSHFYPSIT
                     KVFELNLLSVLGTLVFALLLGYVSAYFPARKISKMDPVEPLRYE"
     gene            1507..2514
                     /gene="gap"
                     /locus_tag="VQ543_002006"
     CDS             1507..2514
                     /gene="gap"
                     /locus_tag="VQ543_002006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008090210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HET2612666.1"
                     /translation="MVVKVGINGFGRIGRLAFRRIQNVEGVEVTRINDLTDPVMLAHL
                     LKYDTTQGRFDGTVEVKEGGFEVNGKFIKVSAERDPEQIDWATDGVEIVLEATGFFAK
                     KEAAEKHLKGGAKKVVITAPGGNDVKTVVFNTNHDVLDGTETVISGASCTTNCLAPMA
                     KALQDNFGVVEGLMTTIHAYTGDQMILDGPHRGGDLRRARAGAANIVPNSTGAAKAIG
                     LVIPELNGKLDGSAQRVPTPTGSVTELVAVLEKNVTVDEVNAAMKAASNESYGYTEDP
                     IVSSDIVGMSYGSLFDATQTKVLDVDGKQLVKVVSWYDNEMSYTAQLVRTLEYFAKIA
                     K"
     gene            complement(2581..3417)
                     /locus_tag="VQ543_002007"
     CDS             complement(2581..3417)
                     /locus_tag="VQ543_002007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000216776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HET2612667.1"
                     /translation="MTVKQLLEEQLLIPRKIRHFLRIKKHILINQEEVHWNEIVNPGD
                     VCQLTFDEEDYPQKTIPWGNPDLVQEVYQDQYLIIVNKPEGMKTHGNQPNEIALLNHV
                     STYVGQTCYVVHRLDMETSGLVLFAKNPFILPILNRLLEKKEISREYWALVDGNINRK
                     ELVFRDKIGRDRHDRRKRIVDAKNGQYAETYVSRLKQFSNKTSLARCKLKTGRTHQIR
                     VHLSHHNLPILGDPLYNSKSKTSRLMLHAFRLSFTHPLTLEKLTFTTLSNTFEKELKK
                     NG"
     gene            3543..5738
                     /locus_tag="VQ543_002008"
     CDS             3543..5738
                     /locus_tag="VQ543_002008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HET2612668.1"
                     /translation="MKLDKLFEKFLSLFKKETSELEDSDSTILRRSRSDRKKLAQVGP
                     IRKFWRRYHLTKIILILGLSAGLLVGIYLFAVAKSTNVNDLQNALKTRTLIFDREEKE
                     AGALSGQKGTYVELTDISKNLQNAVIATEDRSFYKNDGINYGRFFLAIVTAGRSGGGS
                     TITQQLAKNAYLSQDQTVERKAKEFFLALELSKKYSKEQILTMYLNNAYFGNGVWGVE
                     DASKKYFGVSASEVSLDQAATLAGMLKGPELYNPLNSVEDSTNRRDTVLQNMVAAGYI
                     DKNQETEAAEVDMASQLHDKYEGKISDYRYPSYFDAVVNEAVSKYNLTEEEIVNNGYR
                     IYTELDQNYQANMQIVYENTSLFPRAEDGTFAQSGSVALEPKTGGVRGVVGQVADNDK
                     TGFRNFNYATQSKRSPGSTIKPLVVYTPAVEAGWALNKQLDNHTMQYDSYKVDNYAGI
                     KTSREVPMYQALAESLNLPAVAAVNDLGVDKAFEAGEKFGLNMEKVDRVLGVALGSGV
                     ETNPLQMAQAYAAFANEGLMPEAHFISRIENASGQVIASHKNSQKRVIDKSVADKMTS
                     MMLGTFTNGTGISSSPADYIMAGKTGTTEAVFNPEYTSDQWVIAYTPDVVISHWLGFP
                     TTDENHYLAGSTSNGAAHVFRNIANTILPYTPGSTFTVENAYKQNGIAPANTKRQVQT
                     NDNSQTDDNLSDIRGRAQSLVDEASRAISDAKIKEKAQTIWDSIVNLFR"
     gene            5791..5943
                     /gene="rpmG"
                     /locus_tag="VQ543_002009"
     CDS             5791..5943
                     /gene="rpmG"
                     /locus_tag="VQ543_002009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015912025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HET2612669.1"
                     /translation="MALKKASLACAVCGSRNYSIKISGNPKPTRLEVNKFCKHCGKYT
                     THRETR"
     gene            5953..6129
                     /gene="secE"
                     /locus_tag="VQ543_002010"
     CDS             5953..6129
                     /gene="secE"
                     /locus_tag="VQ543_002010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001211016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecE"
                     /protein_id="HET2612670.1"
                     /translation="MRFIGDIFRLLKDTTWPTRKESWRDFRSIMEYTAFFVVIIYIFD
                     QLIVSGLIRFINIF"
     gene            6185..6721
                     /gene="nusG"
                     /locus_tag="VQ543_002011"
     CDS             6185..6721
                     /gene="nusG"
                     /locus_tag="VQ543_002011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000376740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusG"
                     /protein_id="HET2612671.1"
                     /translation="MDSFDKGWFVLQTYSGYENKVKENLLQRAQTYNMLDNILRVEIP
                     TQTVQVEKNGKRKEVEENRFPGYVLVEMVMTDEAWFVVRNTPNVTGFVGSHGNRSKPT
                     PLLEQEIRDILVSMGQTVQEFDFDVEIGQTVRIIDGAFADYTGKITEIDNNKVKMIIS
                     MFGNDTVAEVNLNQIAEL"
BASE COUNT         2139 a         1198 c         1494 g         2049 t
ORIGIN      
        1 cgctccaatg acttacgaag agacgatgac gagcgacttt tttgaagtat ggtttcagaa
       61 gtttttctta ccaacattaa ccacaccatc ggttattatt atggataatg taagattcca
      121 tagaatgggg aagctagaac tcttgtgtga agagtttggg cataaacttt tacctcttcc
      181 tccctactca cctgagtaca atcctattga gaaaacatgg gttcatatca aaaagcacct
      241 caaaaaggta ttaccaagtt gcaatacctt ttacgaggct cttttgtctt gttcttgttt
      301 caattgacta tatatcacgg atacagttgg gaaagaagct attaaacatt tggagagtcc
      361 ttttgggatg aacatgtcaa atattactat agatgggcaa gaaatggatc tgagtcaaac
      421 gatgccttct tatgctcaag tagtgagtct ttatgatgat acaagtatct ctgttagtag
      481 taatgagacg gacaaagtgt tggctggctc cctctatact gatacaaatg aacagggatt
      541 aacgattcca agcagtttac taaaaaattg gaatgaacag acaggaaaaa atttgacagc
      601 taatgatctt attggcaaat cagtctcagc cagcattgta gaaagtgctg ccgaaactag
      661 taagattgct caatttcaaa cgaagattgt acgtgtaatc aatgatgaag atgacatgga
      721 ggacagcaac agtttcatgc tgtctcatca aatggaaacg attttgaaag aggctggatt
      781 tacgaaagct gtatcttatt ttatcttgga actcaaagat ccatcacaga caaaagtagt
      841 aacagaagaa ttacagaaaa ataagaagta tactgtgctt tctcaacaga gagttcttga
      901 tattgtgatt atctttattc gtgttattca gggattattg attgtgcttt catcacaagc
      961 tattgtggta gcagcggtta tgattggtat cattatttac atcaatatca tgcagcgttc
     1021 caaggaaata ggtgtcatga aggcagttgg ttatcagaat cgtgatgtca aaggaatttt
     1081 tatttacgag gctatctgga ttgtaggcat cgccttgctg ctggcatttt tggttgcaca
     1141 aggggtggga agtttggcga atgcgattgt aagtcacttt tacccatcca tcactaaagt
     1201 ttttgaatta aatcttttat ctgttttagg aactctagtt ttcgctctat tacttggtta
     1261 tgtctcagcc tacttcccgg cgcgtaagat tagtaaaatg gatcctgtag aaccgttacg
     1321 ctatgaatag taagggattc cttgatttac agtcttaaaa agaaactaac atagaaaaac
     1381 aatggacata cttgcaattc aactcaaata gttgtataat aggtttgttg aaaggtgatt
     1441 tgtagtgatt caagttactc ttttcacaat aaaaatttca tgattttcat aaggaggaaa
     1501 tcactaatgg tagttaaagt tggtattaac ggtttcggac gtatcggtcg tcttgctttc
     1561 cgtcgtatcc aaaacgtaga aggtgttgaa gttacacgca tcaacgacct tacagatcca
     1621 gttatgcttg cacacttgtt gaaatacgac acaactcaag gtcgtttcga cggtactgtt
     1681 gaagttaaag aaggtggatt tgaagttaac ggtaaattca tcaaagtttc tgctgaacgt
     1741 gatccagaac aaatcgactg ggctactgac ggtgtagaaa tcgttcttga agctactggt
     1801 ttctttgcta agaaagaagc agctgaaaaa caccttaaag gtggagctaa aaaagttgtt
     1861 atcactgctc ctggtggaaa cgacgttaaa acagttgtat tcaatactaa ccacgacgtt
     1921 cttgacggta ctgaaacagt tatctcaggt gcttcatgta ctacaaactg cttggctcca
     1981 atggctaaag ctcttcaaga caactttggt gttgttgaag gattgatgac tactatccac
     2041 gcttacactg gtgaccaaat gatccttgac ggaccacacc gtggtggtga ccttcgccgt
     2101 gctcgcgctg gtgctgcaaa catcgttcct aactcaactg gtgctgcaaa agctatcggt
     2161 cttgtaatcc cagaattgaa tggtaaactt gatggatctg cacaacgcgt tccaactcca
     2221 actggatcag ttactgaatt ggtagcagtt cttgaaaaga acgttactgt tgatgaagtg
     2281 aacgcagcta tgaaagcagc ttcaaacgaa tcatacggtt acacagaaga tccaatcgta
     2341 tcttcagata tcgtaggtat gtcttacggt tcattgtttg acgcaactca aactaaagtt
     2401 cttgacgttg acggtaaaca attggttaaa gttgtatcat ggtacgacaa cgaaatgtca
     2461 tacactgcac aacttgttcg tactcttgaa tacttcgcaa aaattgctaa ataattcttg
     2521 agttgataga aagcaaggct ttgtggtctt gctttttata tggaaaaatg gatgacacga
     2581 tcatccattc ttttttaatt ctttttcaaa tgtatttgaa agggtagtga aagttagctt
     2641 ctctaaagta agtgggtggg taaaggaaag tcggaaggca tgaagcataa gccgacttgt
     2701 ctttgattta ctattataga gagggtcgcc caggatagga agattatgat gcgaaaggtg
     2761 cacacgaatc tgatgggttc gccctgtctt tagcttgcaa cgagccaagg aagtcttgtt
     2821 tgagaattgc tttaatctgc ttacatacgt ttcagcatat tgcccatttt ttgcatcaac
     2881 tattcttttt ctacgatcat ggcgatcacg tccaattttg tctctgaaaa caagttcttt
     2941 tctgttgata tttccatcaa ctagagccca atattctcta gaaatctctt ttttctccaa
     3001 taagcgattg agaatgggca ggataaaagg atttttggca aagagaacta agccactggt
     3061 ttccatgtcc agacgatgaa cgacatagca ggtttggcca acataggtac tgacatggtt
     3121 aagaagggca atttcgtttg gttgattacc atgcgttttc atcccctctg gtttgtttac
     3181 aataatcaag tattgatctt gataaacttc ctgcactaag tctgggttgc cccaagggat
     3241 cgtcttttgg ggataatctt cctcgtcaaa agtcaactgg caaacatctc caggatttac
     3301 gatttcgttc cagtggactt cttcttgatt tatcaaaata tgtttcttga ttctcaaaaa
     3361 atgacggatt tttctaggga tgaggagttg ttcctcaagt aattgcttta ccgtcatttg
     3421 aggtagagag gcgggtaatg taaatgtgaa ttgcatacag atattgtaac aaaaaaagcc
     3481 ctatttggat aggaaatagc taaattcttg tcttcctatg atgaagatga taaaataaac
     3541 gcatgaaatt agataaatta tttgagaaat ttctttctct ttttaaaaaa gaaacaagtg
     3601 aactagagga ctctgattct actatcttac gtcgctctcg tagtgatcga aaaaaattag
     3661 cccaagtagg tccgattcga aaattctggc gtcgttatca tctaacaaag attatcctta
     3721 tactaggttt gagtgcaggc ttgctagttg gaatctattt gtttgctgta gccaagtcga
     3781 ccaatgtcaa tgatttgcaa aatgccttga aaactcggac tcttattttt gaccgtgaag
     3841 aaaaagaggc tggtgccttg tctggtcaaa agggaaccta tgttgagctg actgatatca
     3901 gtaaaaactt gcagaatgct gttattgcga cagaagaccg ttctttctat aaaaatgacg
     3961 ggattaacta tggccgtttc ttcttggcta ttgtcactgc tggacgttca ggtggtggct
     4021 ctaccattac ccaacagctg gctaaaaacg cctatttatc acaggatcaa actgttgaga
     4081 gaaaagcgaa agaatttttc cttgccttag aattaagcaa aaaatatagt aaggagcaaa
     4141 ttctaaccat gtaccttaac aacgcttatt ttggaaatgg tgtgtggggt gtagaagatg
     4201 cgagtaagaa atactttgga gtttctgcat cagaagtgag tctggatcaa gctgcgactc
     4261 tggcagggat gctcaagggg ccggaactgt ataatccctt gaattccgta gaagattcta
     4321 ctaatcggcg cgatactgtc ttgcagaata tggttgcagc aggatatatt gataaaaacc
     4381 aagaaaccga agctgctgaa gttgatatgg cttcgcaatt gcacgataag tatgaaggaa
     4441 aaatctcaga ttaccgttac ccctcttatt ttgatgcggt ggttaatgaa gctgtttcca
     4501 agtataatct aacagaggaa gagattgtca ataatggcta ccgcatttac acagagctgg
     4561 accaaaacta ccaagcaaat atgcagattg tttatgaaaa cacatcgcta tttccgaggg
     4621 cagaggatgg aacgtttgct caatcaggaa gtgtagctct cgaaccgaaa acagggggag
     4681 ttcgtggagt tgtcggtcaa gttgctgaca atgataaaac tggattccgg aatttcaact
     4741 atgcaaccca atcaaagcgt agtcctggtt ctacaattaa gcctttagtt gtttatacgc
     4801 cagcagttga agcaggctgg gctttgaata agcagttgga taaccatacc atgcagtatg
     4861 acagctataa ggttgataac tatgcaggga tcaaaacgag tcgagaagtt cctatgtatc
     4921 aagccttggc agaatcgctt aatctacctg ctgttgccgc tgttaatgat ttgggtgtcg
     4981 acaaggcttt tgaggcaggc gaaaaattcg gactcaacat ggaaaaggtc gaccgtgttc
     5041 ttggtgtcgc cttgggaagc ggtgttgaaa ccaaccctct tcaaatggct caagcatacg
     5101 ctgcctttgc aaatgaaggt ttaatgcctg aagctcattt tattagtaga attgaaaatg
     5161 ctagtggaca agttattgcg agtcataaaa attcacaaaa acgggtgatt gataagtctg
     5221 tagctgacaa gatgaccagt atgatgttgg ggactttcac caacggtacc ggtattagtt
     5281 catcgcctgc agactatatt atggcaggga aaactggaac aactgaagca gttttcaatc
     5341 cggagtacac aagtgaccag tgggtaattg cttatactcc ggatgtagtg attagccact
     5401 ggcttggctt tcctaccact gatgaaaatc actatctagc tggctctact tcaaacggtg
     5461 cagctcatgt ctttagaaac attgccaata ccattttacc ttatacgcca ggaagtacct
     5521 ttacggttga aaatgcttat aagcaaaatg gaattgcacc agccaataca aaaagacaag
     5581 tacaaaccaa tgataatagc cagacagatg ataatttgtc tgatattcga gggcgtgcgc
     5641 aaagtctagt agatgaggct agccgggcta tctcagatgc gaagattaag gaaaaggctc
     5701 aaacaatatg ggattcgata gtcaatctat ttcgctaaga tgcttgtcaa agcctagctt
     5761 tcttgttata atggatagga tggaggcgtt atggcactaa aaaaagcaag cctagcttgt
     5821 gcggtttgtg gttcgagaaa ctattcaatc aagatcagcg gaaaccccaa gcctacacga
     5881 ctagaagtaa ataaattttg taagcattgt ggcaagtaca ctacacacag agaaacgaga
     5941 taggagagag cgatgcgttt tattggagat atttttagac ttcttaaaga cacaacgtgg
     6001 ccaactcgca aggaaagctg gagagatttt cgttctatca tggaatacac agctttcttt
     6061 gtagtaatta tttacatttt tgaccagttg attgtttcag gtttgattcg atttattaac
     6121 attttttaga agattagtgg agttaattac actagaaatc ttctatatta tgaaaggaaa
     6181 tatcatggat agttttgata aagggtggtt tgttttacaa acttattctg gttatgaaaa
     6241 taaggtgaaa gaaaatctat tacaacgtgc acaaacctac aatatgttgg ataatattct
     6301 acgcgttgaa attccaacac aaacagtgca agttgaaaaa aatggaaaga gaaaagaagt
     6361 agaagaaaat cgctttccag gttatgttct tgtagaaatg gtcatgacag atgaagcttg
     6421 gtttgttgtt cgaaacacac caaatgttac aggatttgtc ggatcacacg ggaacagatc
     6481 aaaaccaact ccattattgg aacaagaaat tcgtgacatt ttggtatcta tgggacaaac
     6541 tgttcaagaa tttgatttcg atgttgagat tggtcaaact gtacgtatta ttgatggtgc
     6601 ttttgcagac tacactggta agattacaga aattgataat aacaaagtga aaatgattat
     6661 ctctatgttt ggtaatgaca cagttgcaga agtaaaccta aaccaaatcg cagaattata
     6721 accctgagag aggctggagc ctctcttttt tgtgcagttt aggagctaaa gggaacagaa
     6781 tggagaaaat gtaacaaatg tgttttctaa tctgttagac tgtatctaga aaggggaaaa
     6841 ttatgattaa agaattgtat gaagaagtcc aagggactgt
//
LOCUS       DAVBEO010000077         6518 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 009
            SAMEA1678075-rid20185393.denovo.077, whole genome shotgun sequence.
ACCESSION   DAVBEO010000077 DAVBEO010000000
VERSION     DAVBEO010000077.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678075
            Sequence Read Archive: ERR226392
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6518)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6518)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980207.1
            Genome Coverage       :: 150x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:50:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 72 of 147
            Pseudo Genes (incomplete)         :: 72 of 147
            Pseudo Genes (internal stop)      :: 42 of 147
            Pseudo Genes (multiple problems)  :: 32 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6518
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678075-rid20185393.denovo.077"
                     /strain="KS 009"
                     /db_xref="taxon:1313"
     gene            complement(164..460)
                     /locus_tag="VQ543_002012"
     CDS             complement(164..460)
                     /locus_tag="VQ543_002012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000450185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HET2612672.1"
                     /translation="METSISMADFYGKYQNENLELIDVREAHEFQAGHAPGAKNLPLS
                     TLEQGYKELKPDHEYYVICQGGVRSASTCQFLISQGLTVTNVEGGMNAWPGQVE"
     gene            complement(450..611)
                     /locus_tag="VQ543_002013"
     CDS             complement(450..611)
                     /locus_tag="VQ543_002013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014932007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(FAD)-dependent dehydrogenase"
                     /protein_id="HET2612673.1"
                     /translation="MDKKQAYIVSCHSGLRSYIAEPILKQAGFTAQNLDGAYSLYKMV
                     NPEGVEYGN"
     gene            681..1445
                     /locus_tag="VQ543_002014"
     CDS             681..1445
                     /locus_tag="VQ543_002014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside phosphorylase"
                     /protein_id="HET2612674.1"
                     /translation="MIQKHAIPILEFDDNPQAVIMPNHEGLDLQLPKKCVYAFLDEEI
                     DRYAREVGADCVGEFVSATKTYPVYVINYKGEEVCLAQAPVGSAPAAQFMDWLIGYGV
                     EQIISTGTCGVLADIEENAFLVPVRALRDEGASYHYVAPSRYMEMQPEAIAAIEEVLE
                     DRGIPYEEVMTWTTDGFYRETAEKVAYRKEEGCAVVEMECSALAAVAQLRGVLWGELL
                     FTADSLADLDQYDSRDWGSEAFNKALELSLASVHHL"
     gene            2058..3437
                     /locus_tag="VQ543_002015"
     CDS             2058..3437
                     /locus_tag="VQ543_002015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000897732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HET2612675.1"
                     /translation="MLFKLSKEKIELGLSRLSPARRIFLSFALVILLGSLLLSLPFVQ
                     VESSRATYFDHLFTAVSAVCVTGLSTLPVAHTYNIWGQIICLLLIQIGGLGLMTFIGV
                     FYIQSKQKLSLRSRATIQDSFSYGETRSLRKFVYSIFLTTFLVESLGAILLSFRLIPQ
                     LGWGRGLFSSIFLAISAFCNAGFDNLGSTSLFAFQTDLLVNLVIAGLIITGGLGFMVW
                     FDLAGHVGRKKKGRLHFHTKLVLLLTIGLLLFGTATTLFLEWNNAGTIGNLPVADKVL
                     VSFFQTVTMRTAGFSTIDYTQAHPVTLLIYILQMFLGGAPGGTAGGLKITTFFVLLVF
                     ARSELLGLPHANVARRTIAPRTVQKSFSVFIIFLMSFLIGLILLGITAKGNPPFIHLI
                     FETISALSTVGVTANLTPDLGKLALSVIMPLMFMGRIGPLTLFVSLADYHPEKKDMIH
                     YMKADISIG"
     gene            3451..4116
                     /locus_tag="VQ543_002016"
     CDS             3451..4116
                     /locus_tag="VQ543_002016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001283913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkA family potassium uptake protein"
                     /protein_id="HET2612676.1"
                     /translation="MSDRTIGILGLGIFGSSVLAALAKQDMNIIAIDDHAERINQFEP
                     VLARGVIGDITDEELLRSAGIDTCDTVVVATGENLESSVLAVMHCKSLGVPTVIAKVK
                     SQTAKKVLEKIGADSVISPEYEMGQSLAQTILFHNSVDVFQLDKNVSIVEMKIPQSWA
                     GQSLSKLDLRGKYNLNILGFREQENSPLDVEFGPDDLLKADTYILAVINNQYLDTLVA
                     LNS"
     gene            4230..4325
                     /locus_tag="VQ543_002017"
                     /pseudo
     CDS             4230..4325
                     /locus_tag="VQ543_002017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            4471..4920
                     /locus_tag="VQ543_002018"
     CDS             4471..4920
                     /locus_tag="VQ543_002018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000771906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HET2612677.1"
                     /translation="MKLLSIAISSYNAAAYLHYCVESLVIGGEQVGILIINDGSQDQT
                     QEIAECLASKYPNIVRAIYQENKCHGGAVNRGLAEASGRYFKVVDSDDWVDPRAYLKI
                     LETLQELESKGQEVDAFVTNFVYEKEGQSRKKSMSYESVLPVRQIFD"
     gene            5077..5487
                     /locus_tag="VQ543_002019"
     CDS             5077..5487
                     /locus_tag="VQ543_002019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase family 2"
                     /protein_id="HET2612678.1"
                     /translation="MYYLPVDFYRYLIGREDQSVNEQVMIKRIDQQLKVNRLLVDQLD
                     LSQVSHPKMREYLLNHIEITTVISSTLLNRSETAEHLAKKRQLWTYIQQKNPEVFQAI
                     RKTMLSRLTKHSVLPDRKLSNVVYQITKSVYGFN"
     gene            5603..>6518
                     /gene="pavB"
                     /locus_tag="VQ543_002020"
     CDS             5603..>6518
                     /gene="pavB"
                     /locus_tag="VQ543_002020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin-binding SSURE repeat adhesin PavB"
                     /protein_id="HET2612679.1"
                     /translation="MKFNPNQRYTRWSIRRLSVGVASVVVASGFFVLVGQPSSVRADV
                     VNPTPGQVLPEETSGTKEGDLSEKPGDTVLTQAKPEGVTGNTNSLPTPTERTEVSEET
                     NSSSLDTLFEKDEEAQKNPELTDVLKETVDTADVDGTQASPAETTPEQVKGGVKENTK
                     DSIDVPAAYLEKAEGKGPFTAGVNQVIPYELFAGDGMLTRLLLKASDNAPWSDNGTAK
                     NPALPPLEGLTKGKYFYEVDLNGNTVGKQGQALIDQLRANGTQTYKATVKVYGNKDGK
                     ADLTNLVATKNVDININGLVAKETVEKAV"
BASE COUNT         1770 a         1243 c         1499 g         2006 t
ORIGIN      
        1 acaaccttaa aacagtgttt tgagctgact tcgtcagttc catccacaac cttaaaacag
       61 tgttttgagc agcctgcggc taacttccta gtttgcactt taattttcat tgagtattac
      121 ttcatcttct catgaaattg agtttttgcc cagttcctct tgattattct acttgaccag
      181 gccaagcatt cataccacct tctacgttgg taacggtgag gccttgggag atgagaaatt
      241 ggcaggtaga tgcagagcgg actcctcctt gacaaataac atagtattca tggtcaggtt
      301 tgagttcttt gtagccttgc tctaaggtac ttaatggaag atttttggca cctggtgcat
      361 gtcctgcttg gaattcatgt gcttcacgga catcgataag ttctagattt tcattttggt
      421 attttccata aaagtcagcc atgctgatac tagtttccat attctactcc ttctgggtta
      481 accattttgt atagtgaata agcgccgtca aggttttggg cggtaaatcc tgcttgcttg
      541 aggataggct ctgcgatata gctgcgcaaa ccactgtggc agctgacgat gtaggcttgt
      601 tttttgtcca gttcatcagc ttcctccttg acactttgtc agtttttgat acaatagtac
      661 aaaattagag gaggtgggct atgattcaga aacatgcgat tcctatttta gagtttgatg
      721 acaatcctca ggcggttatc atgcccaatc acgaggggct ggacttgcag ttgccaaaga
      781 agtgtgttta tgcattttta gatgaggaga ttgaccgcta tgcaagggaa gtaggggcgg
      841 attgtgtcgg cgaattcgtt tctgctacca agacctatcc agtctatgtc atcaactaca
      901 agggtgagga ggtctgtctg gctcaggctc ctgttggctc cgctccagca gcccagttta
      961 tggattggtt gattggctat ggtgtggagc agattatctc tactgggacc tgtggtgttc
     1021 tagctgatat agaggaaaat gcctttctag tccctgttcg cgctctgcga gatgaaggag
     1081 ccagttacca ctatgtggca ccttctcgtt atatggaaat gcagccagag gctattgctg
     1141 ctattgagga agttttggaa gacagaggga ttccttatga agaagtcatg acctggacga
     1201 cagacggttt ttaccgagaa acggctgaaa aggtggctta tcgtaaggaa gaaggctgtg
     1261 ctgttgtgga gatggagtgt tctgctcttg cggcagtagc tcaattgcgt ggggttctct
     1321 ggggtgaatt gttgttcaca gcagattctc tagcggactt ggaccagtac gacagtcgtg
     1381 actggggctc ggaagctttt aataaggcgc tagaactgag tttagcaagt gttcaccacc
     1441 tttagttgta ctggcaaagg atttgtttta tcataaaatg tctagctcat acttttcaaa
     1501 aatatgttta aacgaggtca ccttcctctt gtcctaagca tgttgaggtt gggaaaaatc
     1561 tttaaaatca gaaaaacgta tcatatcagg tgatgaaaac cttgatacta tgcgttttat
     1621 gttggtaaga tttagagtga gatgaaatga tactcttcga aaatcttttc aaaccaggtc
     1681 agcttcacct tgccgtaggt atatgttact gacttcgtca gtcttatccg gcaacctcaa
     1741 aacggtgttt tgagctgact tcgtcagttc tatttgcaac ctcaaaacag tgttttgagc
     1801 aatctgtgac tagctttcta atcgatgcct tggttctcat tgcctataat caaaaagaga
     1861 aattttctcc tgaaaagcat atagagtagc tggcgttaaa agctcctgtc ttgctttttt
     1921 gacctatagt cacatctatc aagtattgtt cttgcctaag ctatcaataa aaaggtggca
     1981 ttttttaggc ttggtgttag tagattttgc cttatcctat ctaagtcatt tcgaactttt
     2041 tatggtacaa tggaaacatg ttattcaaat tatctaagga aaaaatagag ctaggcttat
     2101 ctcgtttatc gccagcccgt cgtatttttt tgagttttgc cttggtcatt ttactaggct
     2161 ctcttctttt gagcttgccc tttgtccaag ttgaaagctc acgagcgact tattttgatc
     2221 atcttttcac tgctgtctct gcagtctgtg tgacaggtct ctcaaccctt ccagtagctc
     2281 acacctataa tatatggggc caaataatct gtttgctctt gattcagatc ggtggtctag
     2341 ggctcatgac ctttattggg gttttctata tccagagcaa gcaaaagctt agtcttcgta
     2401 gccgtgcaac tattcaggat agttttagtt atggagaaac tcgatctttg agaaagtttg
     2461 tctattctat ttttctcacg acctttttgg ttgagagctt gggagctatt ttgcttagtt
     2521 ttcgccttat tcctcaactt ggctggggac gtggtctttt tagttccatt tttctagcga
     2581 tctcagcctt ctgtaatgcc ggttttgata atttagggag caccagttta tttgcttttc
     2641 agaccgattt actggtcaat ctggtgattg caggcttgat tattacaggc ggccttggtt
     2701 ttatggtctg gtttgatttg gctggtcatg taggaagaaa gaaaaaagga cgtctgcact
     2761 ttcatacgaa gcttgtacta ttgttgacta taggtttgtt gttatttgga acggcaacta
     2821 ctctctttct tgagtggaac aatgctggaa cgattggcaa tctccctgtt gccgataagg
     2881 ttttagttag cttttttcaa acagtgacga tgcgaacagc tggcttttct acgatagatt
     2941 atactcaggc tcatcctgtg actcttttga tttatatctt acagatgttt ctaggtgggg
     3001 cacctggagg aacagctggg ggactcaaga ttacgacatt ttttgtcctc ttggtctttg
     3061 cacgaagtga gcttctaggc ttgcctcatg ccaatgttgc gagacgaacg attgcgccgc
     3121 gaacggttca aaaatccttt agtgtcttta ttatcttttt gatgagcttc ttgataggat
     3181 tgattctgct agggataaca gccaaaggca atcctccctt tatccacctc atatttgaaa
     3241 ccatttcagc tcttagtaca gttggtgtaa cggcaaatct gactcctgac cttgggaaat
     3301 tggctctcag tgttatcatg ccacttatgt ttatgggacg aattggtccc ttgaccttgt
     3361 ttgttagctt ggcagattac catccagaaa agaaagatat gattcactat atgaaagcag
     3421 atattagtat tggttaagaa aggaaagagc atgtcagatc gtacgattgg aattttgggc
     3481 ttgggaattt ttgggagcag tgtcctagct gccctagcca agcaggatat gaatattatc
     3541 gctattgatg accacgcaga gcgcatcaat cagtttgagc cagttttggc gcgtggagtg
     3601 attggtgaca tcacagatga agaattattg agatcagcag ggattgatac ctgcgatacc
     3661 gttgtagtcg cgacaggtga aaatctggag tcgagtgtgc ttgcggttat gcactgtaag
     3721 agtttggggg taccgactgt tattgctaag gtcaaaagtc agaccgctaa gaaagtgcta
     3781 gaaaagattg gagctgactc ggttatctcg ccagagtatg aaatggggca gtctctagca
     3841 cagaccattc ttttccataa tagtgttgat gtctttcagt tggataaaaa tgtgtctatc
     3901 gtggagatga aaattcctca gtcttgggca ggtcaaagtc tgagtaaatt agacctccgt
     3961 ggcaaataca atctgaatat tttgggtttc cgagagcagg aaaattcccc attggatgtt
     4021 gaatttggac cagatgacct cttgaaagca gatacctata ttttggcagt catcaacaac
     4081 cagtatttgg ataccctagt agcattgaat tcgtaaagag ggatgacccc tcttttttga
     4141 tgcccaagat ggcaaataga gacagaagcc ccttgtcttc tagtaaaagt tcttcaaagg
     4201 ctggacttta tggtaaaata gaaggaagtg acaagagaga gtaatactca atgaaaatca
     4261 aagatcaaac taggaaacta gctgcgggct gctcaaaaca ctgttttgag gttgtggata
     4321 gaactgacga agtcagctca aaacactgtt ttgaggttgc agatagaact gacgaagtca
     4381 gtaacatcta tacggcaagg cgacgttgac gcggtttgaa gagattttcg aagagtataa
     4441 gaaaaaatca gtcccctaaa ggagcagatt atgaagttat tgtctatcgc catttctagc
     4501 tataatgcag cagcctatct tcattactgt gtggagtcgc tagtgattgg tggtgagcaa
     4561 gttgggattt tgattatcaa tgacgggtct caggatcaga ctcaggaaat cgctgagtgt
     4621 ttagctagca agtatcctaa tatcgttaga gccatctatc aggaaaataa atgccatggc
     4681 ggtgcggtca atcgtggctt ggcagaggct tctgggcgct attttaaagt agttgacagt
     4741 gatgactggg tggatcctcg tgcctacttg aaaattcttg aaaccttgca ggaacttgag
     4801 agcaagggtc aagaggtgga tgcctttgtg accaattttg tctatgaaaa ggaaggtcag
     4861 tctcgtaaga agagtatgag ttacgagtca gtcttgcctg ttcggcagat ttttgactag
     4921 gaccaggtcg gaaatttctc caaaggccag tatatcatga tacactcgct gatttatcgg
     4981 acagatttgt tgcgtgctag ccagttctaa ctgcctgaac atacttttta tgtcgatgat
     5041 ctctttgtct ttacgcccct tcagcaggtc aagaccatgt actatctgcc tgtcgatttc
     5101 tatcgttatt tgattgggcg tgaggaccag tctgtcaatg agcaagtgat gattaagcgc
     5161 attgaccagc aactcaaggt caatcgactc ttggtagacc agcttgattt gtcccaagtg
     5221 agtcatccta aaatgcgaga atatctgctg aatcatattg aaatcacgac ggtgatttcc
     5281 agtaccctgc tcaaccgatc tgaaacagcg gagcatctgg caaaaaaacg ccaattgtgg
     5341 acctatattc agcagaaaaa tccagaagtc tttcaggcta ttcgtaagac catgttgagc
     5401 cgtttgacca aacattctgt cttgccagat cgcaaactgt ccaatgtcgt ctatcaaatc
     5461 accaaatctg tttatggatt taattaatat aagtgtttta taagagggat ttaagaaaaa
     5521 ttttaacttt ttcttagtcc tttttaattt caggagatta tactagagtc atcaaataaa
     5581 gaaagactct aaggagaatc ctatgaaatt caatccaaat caaagatata ctcgttggtc
     5641 tattcgccgt ctcagtgtcg gtgttgcctc agttgttgtg gctagtggct tctttgtcct
     5701 agttggtcag ccaagttctg tacgtgccga tgtggtcaat ccgaccccag gtcaagtctt
     5761 acctgaagag acatcgggaa cgaaagaggg tgacttatca gaaaaaccag gagacaccgt
     5821 tctcactcaa gcgaaacctg agggcgttac tggaaatacg aattcacttc cgacacctac
     5881 agaaagaact gaagtgagcg aggaaacaaa ctcttctagt ctggatacac tttttgaaaa
     5941 agatgaagaa gctcaaaaaa atccagagct aacagatgtc ttaaaagaaa ctgtagatac
     6001 agctgatgtg gatgggacac aagcaagtcc agcagaaact actcctgaac aagtaaaagg
     6061 tggagtgaaa gaaaatacaa aagacagcat cgatgttcct gctgcttatc ttgaaaaagc
     6121 tgaagggaaa ggtcctttca ctgccggtgt aaaccaagta attccttatg aactattcgc
     6181 tggtgatggt atgttaactc gtctattact aaaagcttcg gataatgctc cttggtctga
     6241 caatggtact gctaaaaatc ctgctttacc tcctcttgaa ggattaacaa aagggaaata
     6301 cttctatgaa gtagacttaa atggcaatac tgttggtaaa caaggtcaag ctttaattga
     6361 tcaacttcgc gctaatggta ctcaaactta taaagctact gttaaagttt acggaaataa
     6421 agacggtaaa gctgacttga ctaatctagt tgctactaaa aatgtagaca tcaacatcaa
     6481 tggattagtt gctaaagaaa ctgtcgaaaa agctgtta
//
LOCUS       DAVBEO010000078         6447 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 009
            SAMEA1678075-rid20185393.denovo.078, whole genome shotgun sequence.
ACCESSION   DAVBEO010000078 DAVBEO010000000
VERSION     DAVBEO010000078.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678075
            Sequence Read Archive: ERR226392
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6447)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6447)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980207.1
            Genome Coverage       :: 150x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:50:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 72 of 147
            Pseudo Genes (incomplete)         :: 72 of 147
            Pseudo Genes (internal stop)      :: 42 of 147
            Pseudo Genes (multiple problems)  :: 32 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6447
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678075-rid20185393.denovo.078"
                     /strain="KS 009"
                     /db_xref="taxon:1313"
     gene            222..422
                     /locus_tag="VQ543_002021"
     CDS             222..422
                     /locus_tag="VQ543_002021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000226586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2612680.1"
                     /translation="MVASASASSTSTQAQEQVDKSELRALSQELDQRLKALATVSDPK
                     IDATKAVLLDAQKAPEDSALTE"
     gene            447..863
                     /locus_tag="VQ543_002022"
     CDS             447..863
                     /locus_tag="VQ543_002022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000642281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2612681.1"
                     /translation="MKAALDSLKDVKANASDSKPAQDKKDAKQGTEDSKDSDKMTETN
                     SVPAGVIVVSLLALLGVIAFWLIRRKKESEIQQLSTELIKVLGQLDAEKADKKVLAKA
                     QNLLQETLDFVKEENGSAETETKLVEELKAILDKLK"
     gene            1094..1801
                     /gene="ccdA2"
                     /locus_tag="VQ543_002023"
     CDS             1094..1801
                     /gene="ccdA2"
                     /locus_tag="VQ543_002023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004237834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     membrane protein CcdA2"
                     /protein_id="HET2612682.1"
                     /translation="METIVFLISVFLAGVLSFFSPCIFPLLPVYAGILLDDQESAKSF
                     SLFGRKVLWSGLIRTLCFIAGISLIFFILGFGAGYFGHILYANWFRYVMGAIIIILGL
                     HQMEIFHLKKLEVQKSFTFKKSDSNRYWSAFLLGITFSFGWTPCIGPVLSSVLALAAS
                     GGNGAWQGAIYTLIYTLGMALPFLVLALASGLVMPYFSKIKRHMMLLKKIGGFLIVLM
                     GILLLLGQVNVLAGIFE"
     gene            1812..2369
                     /gene="sdbB"
                     /locus_tag="VQ543_002024"
     CDS             1812..2369
                     /gene="sdbB"
                     /locus_tag="VQ543_002024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000757364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     lipoprotein SdbB"
                     /protein_id="HET2612683.1"
                     /translation="MKKVMFAGLSLLSLVVLMACGEEETKKTQAAQQPKQQTTVQQIA
                     VGKDAPDFTLQSMDGKEVKLSDFKGKKVYLKFWASWCGPCKKSMPELMELAAKPDRDF
                     EILTVIAPGIQGEKTVEQFPQWFQEQGYKDIPVLYDTKATTFQAYQIRSIPTEYLIDS
                     QGKIGKIQFGAISNADAEAAFKEMN"
     gene            2490..3881
                     /locus_tag="VQ543_002025"
     CDS             2490..3881
                     /locus_tag="VQ543_002025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001020339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HET2612684.1"
                     /translation="MNIFRTKNVSLDKTEMHRHLKLWDLILLGIGAMVGTGVFTITGT
                     AAATLAGPALVISIVISALCVGLSALFFAEFASRVPATGGAYSYLYAILGEFPSWLAG
                     WLTMMEFMTAISGVASGWAAYFKGLLSQYGIAFPQALNGTFNPQAGTFVDLLPILVLV
                     LVTSLVLLNAKAALRFNSILVILKFSALALFVLVGIWNIKFDNWSNFAPYGFGQIYGA
                     STGIMAGASLMFFGFLGFESISMAVDEVKTPQKNIPRGIVLSLSIVTILYALVTLVLT
                     GVVHYSHLNVDDAVAFALRSVGISWAANYVSLVAILTLITVCISMTYALSRMIYSLAR
                     DGLVPAAFKELTKTSKIPKNATILTGLASAVAAGMFPLASIAAFLNICTLAYLIMLAY
                     GLIRLRKEKGMPKAGEFKTPLVPLLPILSIIICLSFMLQYNMNTWIAFLVALLVGSII
                     YFTYGYKHSTIEE"
     gene            4024..4941
                     /gene="adcAII"
                     /locus_tag="VQ543_002026"
     CDS             4024..4941
                     /gene="adcAII"
                     /locus_tag="VQ543_002026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000744528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding lipoprotein AdcAII"
                     /protein_id="HET2612685.1"
                     /translation="MKKQNLFLVLLSVFLLCLGACGQKESQTGKGMKIVTSFYPIYAM
                     VKEVSGDLNDVRMIQSSSGIHSFEPSANDIAAIYDADVFVYHSHTLESWAGSLDPNLK
                     KSKVKVLEASEGMTLERVPGLEDVEAGDGVDEKTLYDPHTWLDPEKAGEEAQIIADKL
                     SEVDSEHKETYQKNAQAFIKKAQELTKKFQPKFEKATQKTFVTQHTAFSYLAKRFGLN
                     QLGIAGISPEQEPSPRQLTEIQEFVKTYKVKTIFTESNASSKVAETLVKSTGVGLKTL
                     NPLESDPQNDKTYLENLEENMSILAEELK"
     gene            4949..>6447
                     /locus_tag="VQ543_002027"
     CDS             4949..>6447
                     /locus_tag="VQ543_002027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HET2612686.1"
                     /translation="MKINKKYLAGSVAVLALSVCSYELGRHQAGQVKKESNRVSYIDG
                     DQAGQKAENLTPDEVSKREGINAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDAIISE
                     ELLMKDPNYQLKDSDIVNEIKGGYVIKVDGKYYVYLKDAAHADNIRTKEEIKRQKQER
                     SHNHNSRADNAVAAARAQGRYTTDDGYIFNASDIIEDTGDAYIVPHGNHFHYIPKSDL
                     SASELAAAQAYWNGKQGSRPSSSSSHNANPAQPRLSENHNLTVTPTYHQNQGENISSL
                     LRELYAKPLSERHVESDGLVFDPAQITYRTVNGVAVPHGDHYHFIPYSQLSPLEEKLA
                     RMIAVKGQNGAVLPGMHYLKPAPKPQVQPSTEKKQTDFAVEQVVRKVGEGYVVEIAGV
                     SHYVFAKDLAKDKIDAIENLLSKKTQETHALVAKKENVAPRDQEFYDKAYNLLTQAHK
                     VLSENKGRTSDFQALDKLAERLNNESSNKVKLVDDLLAFLAPITHPERLG"
BASE COUNT         1980 a         1172 c         1354 g         1941 t
ORIGIN      
        1 atggtttcag aaatttctct taccaacatt aaccacacca tcggttatta tagtaaaatg
       61 gaataagaac aggacaaatc gatcaggaca gtaaaatcga attctaacaa tgttttagaa
      121 gtctatatgt actattctag tttcaatata ccataactgc tcctagtcaa cctgcaagtc
      181 ctgtcccagc tccaagctca gctccgactc aagatcctag agtggtagca agcgcttcgg
      241 ctagctcaac gagcacacaa gctcaagagc aagttgacaa gtctgaactt cgtgccttga
      301 gtcaagagtt agaccaacgc ttgaaagctt tggcaacagt atctgatcca aaaatcgatg
      361 caaccaaggc tgtcctccta gatgctcaaa aagctccgga agatagtgcc ttgacagagt
      421 aaggtctgca tactgcagta gagtctgtga aggctgcctt ggactctctc aaagatgtga
      481 aagcaaatgc tagcgacagc aagcctgcac aggacaagaa ggatgcaaaa caaggaacgg
      541 aagatagtaa ggattcagat aagatgactg aaacaaactc agttccggca ggagtgattg
      601 tggtcagtct acttgccctc ctaggcgtga ttgccttctg gctgattcgc cgtaagaaag
      661 agtcagaaat ccagcaatta agcacggaat tgatcaaggt tctaggacag ctagatgcag
      721 aaaaagcgga taaaaaagtc cttgccaaag cccaaaacct tctccaagaa acccttgatt
      781 tcgtgaaaga agaaaatggc tcagcagaga cagaaactaa actagtagag gagcttaaag
      841 caatccttga caaactcaag taaaacatga tttatgaaat gtcagaccta aaagacattt
      901 tcgttcacaa aagcagtgac gagtaatcct tgtcgttgct ttttggctat tttgggggat
      961 aagatccgcc ttgactagca aaagaaaaga ttggtccaat agtgcccgat acgattttgc
     1021 gtagcagaaa gcttacaaat aaaattgaat atagtaaaat aggattagaa ttattaagaa
     1081 agttggttct ttattggaaa cgatagtatt tttaatctct gtttttctag caggtgtttt
     1141 atcctttttt tctccttgta tttttcctct tctgccagtc tatgctggga ttttattgga
     1201 tgatcaagaa agtgcaaaaa gcttttcttt gtttgggaga aaggttctct ggtcaggctt
     1261 gattcgaaca ctttgcttta tcgctggtat ctctctcatt ttctttattc taggctttgg
     1321 tgctggttac tttggtcata ttctctatgc aaattggttt cgatatgtca tgggagctat
     1381 tattatcatt ttgggtcttc accagatgga aatttttcat ttgaagaaat tagaagttca
     1441 aaaaagtttt acctttaaaa aatcagattc taatcgttat tggtcagctt ttttacttgg
     1501 tattaccttt agctttggtt ggacaccttg tattggtcca gttttaagtt ctgttttagc
     1561 acttgcggct tctggaggca atggtgcttg gcaaggagcg atttatactc tcatttacac
     1621 tctgggcatg gcccttcctt tcttggtctt ggcactagct tcaggtctag tcatgccata
     1681 ttttagtaaa atcaagcgtc atatgatgct actaaagaaa attggtggtt tcctcattgt
     1741 tttaatggga attttgttac tattaggaca agtaaatgtt ctagctggaa tttttgaata
     1801 aaggaggaca aatgaaaaaa gtaatgtttg ctggcttaag tctcttgtca ttagttgtat
     1861 tgatggcctg tggtgaggaa gaaactaaaa agactcaagc agcacaacag ccaaaacaac
     1921 aaacgactgt acaacaaatt gctgttggaa aagatgctcc agacttcaca ttgcaatcca
     1981 tggatggcaa agaagttaag ttatctgatt ttaagggtaa aaaggtttac ttgaagtttt
     2041 gggcttcatg gtgtggtcca tgcaagaaaa gtatgccaga gttgatggaa ctagcggcga
     2101 aaccagatcg tgatttcgaa attcttactg tcattgcacc aggaattcaa ggtgaaaaaa
     2161 ctgttgagca attcccacaa tggttccagg aacaaggata taaggatatc ccagttcttt
     2221 atgataccaa agcaaccacc ttccaagctt atcaaattcg aagcattcct acagaatatt
     2281 taattgatag ccaaggaaag attggaaaga ttcaatttgg tgctatcagt aatgcggatg
     2341 cagaagcagc atttaaagaa atgaactaga atcgataaaa tctgattaca agatgtagtc
     2401 agattttttt agaaaaacat tttataaata ttcacatatc tcctatattt atggtaaaat
     2461 agaattatca gtttattttg gagtcaaaga tgaatatatt tagaacaaag aatgttagtt
     2521 tagataaaac agagatgcat aggcatttga agttatggga tttgattttg ctgggtatcg
     2581 gagccatggt agggacaggc gtctttacaa tcacaggtac tgcagctgca acacttgctg
     2641 gcccagccct agtgatttca atcgttattt ctgccttgtg tgtgggatta tcagccctct
     2701 tttttgcaga atttgcctcg cgagtacccg ctacaggagg tgcctatagt tacctctatg
     2761 ctatcttagg agaattccct tcctggttgg ctggttggtt aaccatgatg gagttcatga
     2821 cagccatatc aggcgtagct tcgggttggg cagcttattt taaaggcttg ctctctcaat
     2881 acgggatagc ctttcctcag gctttaaatg gtacctttaa tcctcaagca gggacatttg
     2941 ttgatttatt gcctattctt gtcttggtct tggtgacttc gcttgtttta ctaaatgcca
     3001 aggcagcctt acgctttaat tcgattctag ttattttgaa attttccgct ttagctctct
     3061 ttgttttagt aggaatttgg aatattaagt ttgataattg gagcaatttt gctccttacg
     3121 gttttggaca aatctatgga gctagcactg gtattatggc tggtgcgtcc ttgatgttct
     3181 tcggtttttt gggatttgaa tccatctcta tggctgtaga tgaagtcaag actcctcaaa
     3241 aaaatattcc tagagggatt gtcttatcgc tttctatcgt aaccattctc tatgccttgg
     3301 tgacccttgt tttgactggt gtggttcact atagtcattt aaatgtcgat gatgccgttg
     3361 cctttgccct tcgtagtgtt gggattagtt gggcagccaa ctatgtgtca ttagtggcta
     3421 tcttgacctt gattacagtt tgtatttcga tgacctatgc cctatcgcgt atgatttaca
     3481 gtttagcacg tgacggctta gtgcctgctg cctttaagga actgacgaag actagcaaga
     3541 taccaaagaa tgctactatc ttgacaggtc tagcttcagc agtagcagca ggaatgttcc
     3601 cactagccag tattgcagcc tttttaaata tttgtacctt agcctacttg atcatgctgg
     3661 cttatggtct gattcgctta cggaaagaaa aaggaatgcc caaagctggg gaatttaaaa
     3721 caccattggt acctctgtta ccaattttat cgatcatcat ttgtttatcc ttcatgttac
     3781 agtataatat gaacacctgg attgctttcc tagttgcgtt gttagtagga agtattattt
     3841 acttcactta tggctataag cattctacca tagaagaata aagtgaaagt ctattgagtt
     3901 gttgacactc agtagatttt tatatgtgaa agaaatttca aattttttct aaaaatatct
     3961 tgacagatta aattttcagg agtagaatat ttactagtta attaaatggt taaggagttg
     4021 ttcatgaaga aacaaaattt atttttagtc ctgttaagtg tctttctttt gtgtttgggg
     4081 gcttgtggtc aaaaggaaag tcagacagga aaggggatga aaattgtgac cagtttttat
     4141 cctatctacg ctatggttaa ggaagtatct ggtgacttga atgatgttcg gatgattcag
     4201 tcaagtagtg ggattcactc ctttgaacct tcggcaaatg atatcgcagc catctatgat
     4261 gcagatgtct ttgtttacca ttctcataca ctcgaatctt gggcaggaag tctggatcca
     4321 aatctaaaaa aatccaaagt gaaggtctta gaggcttctg agggaatgac cttggaacgt
     4381 gtccctggac tagaggatgt ggaagcaggg gatggagttg atgaaaaaac gctctatgac
     4441 cctcacacat ggctagatcc tgaaaaagct ggagaagaag cccaaattat cgctgataaa
     4501 ctttcagagg tggatagtga gcataaagag acttatcaaa aaaatgcgca agcctttatc
     4561 aaaaaagctc aggaattgac taagaaattc caaccaaaat ttgaaaaagc gactcagaaa
     4621 acatttgtaa cacaacatac agccttttct tatctagcga agagatttgg gcttaatcaa
     4681 cttggtattg caggtatctc tcctgaacaa gaaccaagtc cacgacaact aacagaaatt
     4741 caggaatttg ttaagaccta taaggttaaa acgattttta cagaaagtaa cgcttcttca
     4801 aaagtagctg aaactcttgt caaatcaaca ggtgtgggtc ttaaaactct gaatccttta
     4861 gagtcagacc cacaaaatga caagacctat ttagaaaatc ttgaagaaaa tatgagtatt
     4921 ctagcagaag aattaaagtg aggaaagaat gaaaatcaat aaaaaatatc tagcaggttc
     4981 agtggcagtc cttgccctaa gtgtttgttc ctatgaactt ggtcgtcacc aagctggtca
     5041 ggttaagaaa gagtctaatc gagtttctta tatagatggt gatcaggctg gtcaaaaggc
     5101 agaaaatttg acaccagatg aagtcagtaa gagagagggg atcaacgccg aacaaattgt
     5161 tatcaagatt acggatcaag gttatgtgac ctctcatgga gaccattatc attactataa
     5221 tggcaaggtt ccttatgatg ccatcatcag tgaagaactt ctcatgaaag atccgaatta
     5281 tcagttgaag gattcagaca ttgtcaatga aatcaagggt ggctatgtga ttaaggtaga
     5341 cggaaaatac tatgtttacc ttaaagatgc agcccatgcg gacaatattc ggacaaaaga
     5401 agagattaaa cgtcagaagc aggaacgcag tcataatcac aactcaagag cagataatgc
     5461 tgttgctgca gccagagccc aaggacgtta tacaacggat gatgggtata tcttcaatgc
     5521 atctgatatc attgaggaca cgggtgatgc ttatattgtc cctcacggca atcacttcca
     5581 ctatattcct aagagtgatt tgtctgccag tgaattagct gctgcccaag cctattggaa
     5641 tgggaagcag ggatctcgtc cttcttcaag ttctagtcat aatgcaaatc cagctcaacc
     5701 aagattgtca gagaaccaca atctgactgt cactccaact tatcatcaaa atcaagggga
     5761 aaacatttca agccttttac gtgaattgta tgctaaaccc ttatcagaac gccatgtaga
     5821 atctgatggc ctagtatttg atccggcaca aataacatat cgtacagtca atggtgttgc
     5881 tgtaccgcac ggagaccatt atcactttat tccttattca caactgtcac ctttggaaga
     5941 aaaattggct cgtatgattg ctgttaaggg acaaaatggt gcagtcttgc caggaatgca
     6001 ttatttgaaa ccagcaccaa aaccgcaagt tcaaccatca actgagaaaa aacaaactga
     6061 ttttgcagta gaacaggttg ttagaaaagt tggagaaggc tatgttgtgg aaattgctgg
     6121 tgtcagtcac tatgtttttg ctaaagactt ggctaaggat aagattgatg ctattgaaaa
     6181 tctcttgtct aagaaaactc aagagacaca tgctctagtt gctaaaaaag aaaatgtcgc
     6241 tcctcgtgac caagaatttt atgataaagc ttacaatctg ttaacccagg ctcataaagt
     6301 cttgtctgaa aataaaggtc gtacttctga tttccaagcc ttagacaaat tagcagaacg
     6361 cttgaataat gaatcttcta ataaagtaaa attggtagat gatttattgg cattcctagc
     6421 accaattacc cacccagaac gccttgg
//
LOCUS       DAVBEO010000079         6183 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 009
            SAMEA1678075-rid20185393.denovo.079, whole genome shotgun sequence.
ACCESSION   DAVBEO010000079 DAVBEO010000000
VERSION     DAVBEO010000079.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678075
            Sequence Read Archive: ERR226392
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6183)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6183)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980207.1
            Genome Coverage       :: 150x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:50:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 72 of 147
            Pseudo Genes (incomplete)         :: 72 of 147
            Pseudo Genes (internal stop)      :: 42 of 147
            Pseudo Genes (multiple problems)  :: 32 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6183
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678075-rid20185393.denovo.079"
                     /strain="KS 009"
                     /db_xref="taxon:1313"
     gene            complement(115..747)
                     /locus_tag="VQ543_002028"
     CDS             complement(115..747)
                     /locus_tag="VQ543_002028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000200889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HET2612687.1"
                     /translation="MTSITAIFFDLDGTLVDSSIGIHNAFTYTFKELGVPSPDAKTIR
                     GFMGPPLESSFATCLSKDQISEAMQIYRSYYKAKGIYEAQLFPQIIDLLEELSSSYPL
                     YITTTKNTSTAQDMAKNLEIHHFFDGIYGSSPEAPHKADVIHQALQTHQLAPEQAIII
                     GDTKFDMLGARETGIQKLAVTWGFGEQADLLNYQPDYIAHKPLEVLAYFQ"
     gene            complement(769..1641)
                     /gene="sdaAA"
                     /locus_tag="VQ543_002029"
     CDS             complement(769..1641)
                     /gene="sdaAA"
                     /locus_tag="VQ543_002029"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent,
                     subunit alpha"
                     /protein_id="HET2612688.1"
                     /translation="MFYSIKELVEQADLDFQGNVAELMITTEFELTGREREEVFLLME
                     RNLEVMKASVQLGLNENKSRSGLTGGDAAKLDHYIKNEKTLSDYTILSAARNAIAVNE
                     HNAKMGLVCATPTAGSAGCLPSVLTAAIEKLDLSHEQQLDFLFAAGAFGLVIANNASI
                     SGAEGGCQAEVGSASAMSAAALTLAAGGTPYQASQAIAFVIKNMLGLICDPVAGLVEV
                     PCVKRNAMGASFAFIAADMALAGIESKIPVDEVIDAMYQVGASMPTAFRETAEGGLAT
                     TPTGRRLQKEIFGE"
     gene            complement(1650..2321)
                     /gene="sdaAB"
                     /locus_tag="VQ543_002030"
     CDS             complement(1650..2321)
                     /gene="sdaAB"
                     /locus_tag="VQ543_002030"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015606087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent
                     subunit beta"
                     /protein_id="HET2612689.1"
                     /translation="MKSLRFQSVFDIIGPVMIGPSSSHTAGAVRIGKIVSSIFDDTPT
                     EVEFQLFNSFAKTYRGHGTDLALVAGILGMDTDDPEIPNSLEIAHKRGIKIVWTIQKD
                     SNAPHPNTTKITVKNAHKTISVTGISIGGGNIQVTELNGFAVSLNMNTPTIIIVHQDI
                     PGMIALVTEALSRYGINIAQMNVTREKAGEKAIMIIEVDSRNCDEAIEEIRKIPHLHN
                     VNFFK"
     gene            2563..3135
                     /locus_tag="VQ543_002031"
     CDS             2563..3135
                     /locus_tag="VQ543_002031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000843467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HET2612690.1"
                     /translation="MKSITKKIKATLAGVAALFAVFSPSFVSAQESSTYTVKEGDTLS
                     EIAETHNTTVEKLAENNHIDNIHLIYVDQELVIDGPVAPVATPAPATYAAPAAQDETV
                     SAPVVSETVVSTVSGSEAEAKEWIAQKESGGSYTATNGRYIGRYQLTDSYLNGDYSAE
                     NQERVADAYVAGRYGSWTAAKNFWLNNGWY"
     gene            complement(3187..4050)
                     /locus_tag="VQ543_002032"
     CDS             complement(3187..4050)
                     /locus_tag="VQ543_002032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001268160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET2612691.1"
                     /translation="MRYDFGKVYKEIRESKGLTQEEVCGGVLSRTSLSKIESGKTTPK
                     YENMEFLLRQINMSFEEFEYICQLYQPSQRTEIMQTYLNMRSIIGTSDLVNLFQKCQD
                     YLKTHHDLPIEEIRDMLEVVIYLRQHGAGELSKHAEQVVKKLWKKIEKQDTWYESDLK
                     ILNTILFSFPIEYLHLITGKILQRLEVYKNYQHLYDLRMTILLNLSTLYLYNQDKNMC
                     KQICYTLLEDAKNKKSYDRLAICYVRIGICTDDSKLIQKGFSLLELTEETSMLSHLKK
                     EVEIYYQAKER"
     gene            4516..4854
                     /locus_tag="VQ543_002033"
     CDS             4516..4854
                     /locus_tag="VQ543_002033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000915343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase C39"
                     /protein_id="HET2612692.1"
                     /translation="MLKKYPCTMQHDQSDCAAAVVSTVLLSYKKELSIMKIREIIGTD
                     MYGTTVSGIVSGLNKLNFTVKAVRVALEDLTPKLTFPAILQVKNDLGQNHFVVLHSIK
                     EKINGTRITK"
     gene            4832..5191
                     /locus_tag="VQ543_002034"
     CDS             4832..5191
                     /locus_tag="VQ543_002034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2612693.1"
                     /translation="MELVLPNNYVVIDEEEMMYLDGGAIYIPRWAITGAITGAAYAAL
                     AAAGGGGLQLVLASYGLRSALVAGIVKGLGVLGIHIGNAFANTVIRSIASAGIGAGAD
                     WILPILLMAGMGDVIIN"
     gene            5210..5422
                     /locus_tag="VQ543_002035"
     CDS             5210..5422
                     /locus_tag="VQ543_002035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000989850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2612694.1"
                     /translation="MMVVLISVIVAFLYHKITEYVNNRKIDIVIFLSLLISHFIWNYY
                     FLPIEILIAISGANLLLSFLKKLQIK"
     gene            5837..5905
                     /locus_tag="VQ543_002036"
                     /pseudo
     CDS             5837..5905
                     /locus_tag="VQ543_002036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424474.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate lyase"
     gene            5885..>6183
                     /locus_tag="VQ543_002037"
     CDS             5885..>6183
                     /locus_tag="VQ543_002037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate lyase"
                     /protein_id="HET2612695.1"
                     /translation="MMYLDGGGVGCNWWNKRDNIAAAAVSGGMSVYQTYAIKKLIANR
                     GMMSRVVRSAITRYIGGVSMATITNALNIAATVAEVFSLGGAIAYGLDIVDGKFDG"
BASE COUNT         1900 a         1049 c         1311 g         1923 t
ORIGIN      
        1 acaaccttaa aacagtgttt tgagcagccc gcagctagtt tcctagtttg ctctttgatt
       61 ttcattgagt attacttcat tttcttctga aatagagttg tcgcccagtc tatgctattg
      121 aaaatacgcc aaaacttcta agggtttgtg agcgatataa tcaggttgat agtttagtag
      181 atctgcttgc tctccaaatc cccaagtgac ggccaatttc tgaatacctg tttctcgagc
      241 tcccagcata tcaaacttgg tatctccgat gatgatggct tgttctggtg ctagttgatg
      301 tgtctgtaag gcttggtgaa tgacatctgc cttatggggt gcttcagggc tagaaccata
      361 aataccatca aagaaatgat ggatttccaa gtttttggcc atgtcttgag cagtagatgt
      421 attctttgtc gtggtgatgt agagtggata actgctcgat aactcctcaa gcaagtctat
      481 aatctgagga aagagttgag cttcatagat gccttttgcc ttatagtaag aacgatatat
      541 ctgcatggct tcagaaattt ggtctttgga caggcaggtc gcaaaactac tttcgagagg
      601 tggtcccata aaaccacgaa tagttttggc atcagggcta ggcaccccca gctctttaaa
      661 ggtataggta aaggcattgt gaatcccgat agaactatca acgagggttc catccaaatc
      721 gaaaaaaatc gctgtgatag aggtcatggt ttctcctatt tgataagctt attctccgaa
      781 aatctctttt tggaggcgac gaccagtagg ggtggtagcg agtccacctt cagctgtttc
      841 acgaaaggca gttggcatgc ttgctcctac ttggtacatg gcatcgatca cttcatccac
      901 agggatttta gattcgatac ctgccaaggc catgtctgct gcgatgaaag caaagctagc
      961 tcccatggca ttacgtttga cacagggaac ttcgaccaaa cctgcaacag ggtcacagat
     1021 gaggcctagc atatttttaa tgacaaaggc aatagcttga ctggcctgat aaggtgttcc
     1081 acctgcagcc agagtcaagg cggcagcact catagcagag gctgaaccaa cttcagcttg
     1141 acacccaccc tcagcacctg agatggaggc attgtttgcg atgactagtc caaaggcacc
     1201 agcagcaaag aggaaatcca attgttgctc gtggctgagg tctaattttt caatagcagc
     1261 agtgagaacg gaagggagac aaccggcact tcctgcggta ggagtagcgc agaccaagcc
     1321 cattttagca ttgtgttcat tgactgcgat agcatttcgg gcagcagaga gaatcgtgta
     1381 atctgataaa gttttttcgt ttttgatgta gtgatccaat ttggcagcat ctccacctgt
     1441 caggccacta cgagatttat tttcattgag gccaagttgg acagaggctt tcataacttc
     1501 cagattgcgt tccatgagaa ggaagacttc ttcacgttcg cgaccggtca attcaaactc
     1561 tgttgtaatc atgagttctg cgacatttcc ttgaaagtcc agatctgctt gctcgaccaa
     1621 ttctttgata gaataaaaca tgcttcctcc tatttaaaga aattgacatt gtggagatga
     1681 gggatttttc gaatttcttc gatagcctca tcacagttgc gactgtcaac ttcgataatc
     1741 ataatggctt tttcaccagc tttttcacga gtgacattca tctgggcgat attgatacca
     1801 tagcgggaaa gcgcctctgt aacaagggca atcatacctg gaatatcttg atgaacgatg
     1861 atgatagtcg gtgtattcat attgagagag acggcaaaac cattgagttc ggttacctga
     1921 atatttcctc caccgataga aataccagtc acgctgatgg tcttgtgggc atttttaaca
     1981 gtaattttag tggtgttagg gtgaggggca ttgctgtctt tctgaatggt ccagacaatc
     2041 ttgataccac gcttgtgggc aatttccaga ctatttggaa tttcaggatc atctgtatcc
     2101 attcctaaaa tacctgcaac aagggctagg tctgttccgt gaccacgata ggtcttggca
     2161 aatgagttaa aaagttggaa ttcaacttct gtcggagtat catcaaaaat ggaagagaca
     2221 atcttcccaa tacgaacagc accagcggta tggctactag atgggccaat cataactggt
     2281 ccgatgatat caaagacaga ttgaaaacga agtgatttca tcagtttccc cttataaaaa
     2341 ttcttatctc tattatatca aagaatgagg ggcttggctt taattgtgga tgaaaacctt
     2401 tctaatacct caaatagcat aaaaatagta tcttttatga caaaaaacac cttatttagg
     2461 gaaataaaaa ataattttgt aatatttcta cataaaagtg tcaagaaaca gtaatattta
     2521 aagggtatga tagaactata gaaagaagga gaattttcga atatgaaatc aataactaaa
     2581 aagattaaag caactcttgc aggagtagct gccttgtttg cagtattttc tccatcattt
     2641 gtatctgctc aagaatcatc aacttacact gttaaagaag gtgatacact ttcagaaatc
     2701 gctgaaactc acaacacaac agttgaaaaa ttggcagaaa acaaccacat tgataacatt
     2761 catttgattt atgttgatca agagttggtt atcgatggcc ctgtagcgcc tgttgcaaca
     2821 ccagcgccag ctacttatgc ggcaccagcc gctcaagatg aaactgtttc agctccagta
     2881 gtaagtgaaa cagttgtttc aactgtaagc ggatctgaag cagaagccaa agaatggatc
     2941 gctcaaaaag aatcaggtgg tagctataca gctacaaatg gacgttatat cggacgttac
     3001 caattaacag attcatacct gaacggtgac tactcagctg aaaaccaaga acgtgtagca
     3061 gatgcctacg ttgcaggacg ttacggttca tggactgctg ctaaaaactt ctggcttaac
     3121 aatggctggt attaagaact aacgaacaaa taatatgtaa agagtcgagg aaatccctcg
     3181 gcttttttat ctttccttcg cttggtaata gatctctact tcttttttga gatgagacag
     3241 catagaagtt tcctcggtta gctccagaag ggagaaccct ttttggataa gtttagaatc
     3301 gtctgtacaa atcccaatac ggacatagca gatagccagc ctatcgtagc ttttcttatt
     3361 cttggcgtcc tccagtaaag tgtagcagat ttgcttacac atgtttttat cttgattgta
     3421 tagatagagt gtggaaaggt ttaatagaat tgtcattcgc aagtcatata aatgttgata
     3481 gtttttatag acttctaggc gttgcaatat ttttccagtg atgagatgga ggtattcaat
     3541 gggaaaactg aaaagaatgg tattgaggat ttttagatca ctctcatacc atgtatcttg
     3601 tttttcaatt tttttccaaa gttttttgac aacctgttct gcgtgttttg atagttcccc
     3661 tgccccgtgt tgacggagat aaataacaac ttcaagcata tctctgattt cttctatagg
     3721 gagatcgtgg tgggtcttga ggtagtcttg gcatttttga aataaattga caagatcgct
     3781 ggtcccgata atggaacgca tattgagata ggtttgcata atctctgtgc gttgacttgg
     3841 ttgataaagt tgacagatat attcaaactc ttcaaaactc atattgattt gacggagaag
     3901 aaattccata ttttcatatt ttggggttgt cttgccactt tcgatttttg ataagctggt
     3961 tcttgagaga acacccccac agacctcttc ttgggtcagc ccctttgact cacgtatttc
     4021 tttatagacc tttccgaaat cataacgcat gattttctcc tttctgtgaa aaaagttaac
     4081 aaacaataaa attttgttaa aaatattgta tcatagcaat gtaaaaagta aaaaagaaag
     4141 tcgaaataaa tttgtgaaaa aagttaacgt aattttaaaa tgagcttaat aagaggtatg
     4201 atgtaggtag aaaataaaga taggagaaaa agtatgaata aaaaaatatt ttgtattcta
     4261 gtatgtatta tatcattgat tagtctggcc ataatctttc catggggctg gtcgatataa
     4321 tgtaagggag cttgagttgt taaaggaggc ttagtccttg gacaaaaatc tgctgtacta
     4381 caatgcttgg aaagatatca agaacaaaga atgatacgat tgaaaataaa ctgattcaag
     4441 aactactggg cagtgattga ggtttgggtg acatcaaaga aaagttagat taattctaaa
     4501 gaattgagta tttctatgtt aaaaaaatat ccttgtacga tgcaacatga tcagtcagat
     4561 tgtgctgcgg cagttgtttc aacagttctt ttatcttaca aaaaggaact atcaatcatg
     4621 aagattcggg aaattattgg tacagacatg tatggaacga ctgtcagtgg tattgtttca
     4681 ggtctgaata agttgaattt tacagtaaaa gctgttcgag tagcactgga agatttgact
     4741 ccaaaattaa catttcctgc gattcttcaa gttaagaatg atttaggtca aaatcatttt
     4801 gtggtattac atagtataaa ggagaaaata aatggaactc gtattaccaa ataattatgt
     4861 tgtgattgat gaagaagaga tgatgtacct tgatgggggg gctatatata tacccaggtg
     4921 ggcaattaca ggagccatta ctggtgcagc atatgcagca ttagcagcag caggaggtgg
     4981 aggccttcaa ctagttcttg catcttatgg attacgctcc gcactggtag ctgggattgt
     5041 taaaggttta ggagtattag gaattcatat tggaaatgct tttgcaaata ctgttattag
     5101 aagtattgca tctgctggaa ttggtgctgg agctgattgg attttaccaa tattattgat
     5161 ggctgggatg ggcgacgtga taatcaattg agaataggat aatagtatta tgatggttgt
     5221 tttaatttca gttattgttg cattcctgta ccataaaatt acagagtatg tcaacaacag
     5281 gaaaattgat attgttattt ttctatcatt gctgatttct cattttattt ggaattacta
     5341 ttttttacca attgaaatat tgatagcaat cagtggagca aatttattat taagtttttt
     5401 aaaaaaatta cagattaaat aatattattc catatgacat atcaactagg tcattagatt
     5461 ttattgaaga tataaattaa aaacgaggtt gggaaaaaac tcaatttgaa agtgaaattg
     5521 agtaaatttt tctattatat aacgcatatt atcaagattt ttgaacacct gataatatgc
     5581 acttttctta ttttaaagat tttttgcctt tcttcatttc ttgaatgaat tggagagatg
     5641 actttattta ggtgtttgac attactatag ataggattta gcagtactaa tatgaactca
     5701 tattataggt gcagacttaa attttggaag caagctaaag gatatcttat ctaggtaact
     5761 aagtgctata aacaaagtca acgatcactt gttaggaaac gatcctaact atgcttaata
     5821 aaaaaggaga aaataaatgg aactcgtatt accaaataat tatgttgttc ttgagcaaga
     5881 agagatgatg tatcttgatg ggggtggtgt tggttgtaac tggtggaaca aacgtgataa
     5941 tattgctgca gctgcagttt ctggagggat gtcagtatac cagacatatg ccattaaaaa
     6001 gttaattgct aatcgtggta tgatgagccg agtcgttaga agtgctataa caagatatat
     6061 tggtggagtt agtatggcaa ctattactaa tgctcttaat attgcggcta ctgttgctga
     6121 agttttctca ttaggaggag ccattgcata tggtttagat atcgtagacg gtaaatttga
     6181 tgg
//
LOCUS       DAVBEO010000080         4871 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 009
            SAMEA1678075-rid20185393.denovo.080, whole genome shotgun sequence.
ACCESSION   DAVBEO010000080 DAVBEO010000000
VERSION     DAVBEO010000080.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678075
            Sequence Read Archive: ERR226392
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4871)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4871)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980207.1
            Genome Coverage       :: 150x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:50:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 72 of 147
            Pseudo Genes (incomplete)         :: 72 of 147
            Pseudo Genes (internal stop)      :: 42 of 147
            Pseudo Genes (multiple problems)  :: 32 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4871
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678075-rid20185393.denovo.080"
                     /strain="KS 009"
                     /db_xref="taxon:1313"
     gene            191..409
                     /locus_tag="VQ543_002038"
     CDS             191..409
                     /locus_tag="VQ543_002038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001859328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-export chaperone SecB"
                     /protein_id="HET2612696.1"
                     /translation="MKKISVTVIGYFEINIDENITDILYVNGTAILYHYLRSIVSIVS
                     AIDSSEAMLLPTINVLELLDKSQPFEEE"
     gene            1454..2446
                     /locus_tag="VQ543_002039"
     CDS             1454..2446
                     /locus_tag="VQ543_002039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HET2612697.1"
                     /translation="MAMIEVEHLQKNFVKTVKEPGLKGALRSFIHPEKQTFEAVKDLT
                     FEVPKGQILGFIGANGAGKSTTIKMLTGILKPTSGFCRINGKIPQDNRQDYVKDIGVV
                     FGQRTQLWWDLALQETYTVLKEIYDVPDSLFHKRMDFLNEVLDLKDFIKDPVRTLSLG
                     QRMRADIAASLLHNPKVLFLDEPTIGLDVSVKDNIRRAITQINQEEETTILLTTHDLS
                     DIEQLCDRIFMIDKGQEIFDGTVSQLKETFGKMKTLSFELLPGQSHLVSHYDGLSDMT
                     IDRQGNSLNIEFDSSRYQSADIIKQTLSDFEIRDLKMVDTDIEDIIRRFYRKEL"
     gene            2448..3266
                     /locus_tag="VQ543_002040"
     CDS             2448..3266
                     /locus_tag="VQ543_002040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000240175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-2 family transporter protein"
                     /protein_id="HET2612698.1"
                     /translation="MIKLWRRYKPFINAGVQELITYRVNFILYRIGDVMGAFVAFYLW
                     KAVFDSSQESLIQGFSMADITLYIIMSFVTNLLTRSDSSFMIGEEVKDGSIIMRLLRP
                     VHFAASYLFTELGSKWLIFISVGLPFLSVIVLMKIISGQGIVEVLGLTVIYLFSLTLA
                     YLINFFFNICFGFSAFVFKNLWGSNLLKTSIVAFMSGSLIPLAFFPKVVSDILSFLPF
                     SSLIYTPVMIIVGKYDASQILQALLLQFFWLLVMVGLSQLIWKRVQSFITIQGG"
     gene            3268..4053
                     /locus_tag="VQ543_002041"
     CDS             3268..4053
                     /locus_tag="VQ543_002041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003010202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET2612699.1"
                     /translation="MKKYQRMHLIFIRQYIKQIMEYKVDFVVGVLGVFLAQGLNLLFL
                     NVIFQHIPFLEGWTFQEIAFIYGFSLIPKGMDHLFFDNLWALGQRLVRKGEFDKYLTR
                     PINPLFHILVETFQIDALGELLVGGILLGTTVTSIVWTLPKFLLFLVCIPFATLIYTS
                     LKIATASIAFWTKQSGAMIYIFYMFNDFAKYPISIYNSLLRWLISFIVPFAFTAYYPA
                     SYFLQEKDVFFNVGGLMLISLVFFVISLKLWDKGLDSYESAGS"
     gene            4092..4370
                     /locus_tag="VQ543_002042"
     CDS             4092..4370
                     /locus_tag="VQ543_002042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family acetyltransferase"
                     /protein_id="HET2612700.1"
                     /translation="MFVIEEVKDENQKKAVVAEVLKDLPEWFGIPESTQAYIEGTTTL
                     QVWTAYQESDLTRFVSLSYSSEDCAEIDCLGVKKLIKVEKLGANCLLL"
     gene            4355..4552
                     /locus_tag="VQ543_002043"
     CDS             4355..4552
                     /locus_tag="VQ543_002043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET2612701.1"
                     /translation="MLATLESEARKKVGYLQVKTVAEGSNKDYDRTNDFYRGLGFKKL
                     EIFPQLWNPQNPCQILIKKLE"
BASE COUNT         1399 a          796 c         1022 g         1654 t
ORIGIN      
        1 ggctagtttc ctagtttgct ctttggtttt catttagtat aacagattgt tagaagttgg
       61 tttaaatttc ctaatcagtt tgttcacatt taccttcgat atattatatc ccatagttaa
      121 ggttggtcat acagatgatt atagtcatgg agccgtaaaa cttagtgttt ctttagttga
      181 caaagatgcc atgaaaaaaa tatctgtaac tgtaatagga tattttgaaa taaatataga
      241 tgaaaatatc accgatattc tatacgtaaa tggtactgct attctttatc attatttacg
      301 ttctattgtt tcaatagttt cggcaattga tagcagtgaa gcaatgttgc tacctaccat
      361 taatgtttta gagttactag ataaatctca accttttgaa gaagaataat ttattagctc
      421 actaaattga gggtaaggaa aagtaaaatc agtaagaaaa atgtcttgca ttatacagca
      481 accttttggg aatgagtaga tggattgaat aaaattttat taagagtgga tgatttatct
      541 gtagattatt attggacagt tagtcttgaa gtagtctaag aattaggtta taatcagtag
      601 aatccttgct aataatgagg aggttagttt atgtatagta gactgaatct aaaatagtac
      661 gaaacaattg ctaaaacatt tatagaaatt aattttactt tcccaatcga tttgttctca
      721 tcttatttca atccgctata tattatggta tcgaatcttc atcagaatga taaaattaat
      781 caattgatat ctgattacaa acagaatatg aaagcttttt atatcactat tgaaaaattt
      841 atacgagatg atgaaagcct taagtgttat tttataaagg ttatttcaag tcgttccaag
      901 gtaacaagtc tagatcagat tgaagctgat aaaacgatac aaagaaaata ttcaagtgag
      961 ctaaaaaaat ttattggatt ttataatgag attatttgtg aggaaaatag tttcctacat
     1021 gtacgaaaga ggtggtcgag ttggtttagg tagtcgatgc gtgagttgat aattctcagg
     1081 gtatggactt ctttttcatg aatgaggtaa aagagcaggt attgtttaga gacaatcatt
     1141 ctgagcatat tttctggata gagggagtat ccgattttat gatcaaagtt aataccgccc
     1201 tctggtgaga agatgagtag gttggtaatt taaactatta aacagaattt ttgattaaaa
     1261 gtattatttt atgagagaaa tcctaatttc acaatccata ggcaaactct tgcatttcgt
     1321 tttttattgg actataatag gttggtataa agccttttgt agtaataaaa tgtagaaggt
     1381 gtagaaagca aggatttaga atatttgtag ttaaaaacac aatgttgcta ttccttacga
     1441 tagggagata gatatggcaa tgatagaagt ggaacatctt cagaaaaatt ttgtgaagac
     1501 tgttaaggaa ccgggcttga agggggcttt gcgctccttt attcatcctg aaaagcagac
     1561 ctttgaagcg gtcaaggatt tgacctttga ggttccaaaa gggcagattt taggatttat
     1621 cggggcaaat ggtgctggga agtcgacaac cattaaaatg ctgacaggaa ttttgaaacc
     1681 aacatctggt ttttgtcgga ttaacggcaa gattccccag gacaatcggc aagattatgt
     1741 caaagatatt ggcgtagtct ttggacaacg cacccagcta tggtgggatt tggctctgca
     1801 agagacctac actgtcttaa aagagattta tgatgtgcca gactcgctct ttcataagcg
     1861 tatggacttt ttgaatgaag tcttggattt gaaggacttt atcaaggatc ccgtgcggac
     1921 tctttcactg ggacaacgga tgcgggcgga tattgcggcc tccttgctcc acaatcccaa
     1981 ggttcttttt ttagatgagc cgaccattgg tttggacgtt tcggttaagg ataatattcg
     2041 tcgggcaatt actcagatca atcaagagga agaaactacc attcttttga ccactcacga
     2101 tttgagtgat attgagcaac tttgtgatcg gattttcatg attgacaagg ggcaagagat
     2161 ttttgatgga acggtgagcc aactcaagga gacctttggt aagatgaaga ctctctcttt
     2221 tgaactgcta ccaggtcaaa gtcatctcgt ctctcactat gacggtctgt ctgatatgac
     2281 cattgataga caaggaaaca gcctcaacat tgaatttgat agttctcgct accagtcagc
     2341 tgacattatc aagcaaaccc tgtctgattt tgaaatccgc gatttgaaga tggtggatac
     2401 ggatattgag gatattatcc gtcgcttcta ccgaaaggag ctctaggatg atcaaattgt
     2461 ggagacgtta taaacccttt atcaatgcag gggttcagga gttgattact taccgagtca
     2521 actttattct ctatcggatt ggcgatgtca tgggggcttt tgtggccttt tatctctgga
     2581 aggctgtctt tgattcttcg caagagtctt tgattcaggg cttcagtatg gcggatatca
     2641 ccctctacat catcatgagt tttgtgacca atcttctgac tagatccgat tcgtccttta
     2701 tgattgggga ggaggtcaag gatggctcca ttatcatgcg tttgttgcga ccagtgcatt
     2761 ttgcggcctc ctatcttttc accgagcttg gttccaagtg gttgattttt atcagcgttg
     2821 gccttccatt tttaagtgtc attgtcttga tgaaaatcat atcgggtcaa ggtattgtag
     2881 aggtgctagg attaactgtc atttatcttt ttagcttaac gctcgcctat ctgattaact
     2941 ttttctttaa tatttgcttt ggattttcag cctttgtgtt taaaaatctt tggggttcca
     3001 acctacttaa gacttccata gtggctttta tgtcggggag tttgattccc ttggcattct
     3061 ttccaaaggt tgtttcagat attctctcct ttttgccttt ttcatccttg atttatactc
     3121 cagttatgat cattgttgga aaatacgatg ccagtcagat tcttcaggca ctccttttgc
     3181 agttcttctg gctcttagtg atggtgggat tgtctcagtt gatttggaaa cgggtccagt
     3241 cctttatcac cattcaagga ggttagtatg aaaaaatatc aacgaatgca tctgattttt
     3301 atcagacaat acatcaaaca aatcatggaa tataaggtgg attttgtggt tggtgtcttg
     3361 ggagtctttc tggctcaagg cttgaatctc ttgtttctca atgtcatctt tcaacatatt
     3421 ccattcctag aaggctggac ctttcaagag atagctttca tttatggatt ttccttgatt
     3481 cccaagggaa tggaccatct cttttttgac aatctctggg cactagggca acgcctagtc
     3541 cgaaaagggg agtttgacaa gtatctgact cgtcccatca atcctctctt tcacatccta
     3601 gttgaaacct ttcagattga tgccttgggt gaactcttag tcggtggtat tttattggga
     3661 acaacagtga ccagcattgt ttggactctt ccgaaattcc tgcttttcct agtttgtatt
     3721 ccttttgcga ccttgattta tacttctctt aaaatcgcaa cagccagtat cgccttttgg
     3781 actaagcagt caggcgccat gatttacatc ttctatatgt tcaatgactt tgctaagtat
     3841 ccgatttcta tttacaattc tcttcttcgt tggttgatta gctttatcgt gcctttcgcc
     3901 tttacagcct actatccagc tagctatttc ttacaggaaa aggatgtgtt ctttaacgta
     3961 ggaggtttga tgttgatttc tctggttttc tttgttattt cccttaaact ttgggataag
     4021 ggcttagatt cctacgaaag tgcgggttcg taaaagctaa agtaagacta aaatcaagaa
     4081 agaaacttat gatgtttgta attgaagaag tcaaggatga aaatcaaaaa aaggcagttg
     4141 tagctgaggt tttgaaggat ttgccagaat ggtttggaat cccagaaagc acacaagcct
     4201 atatagaagg aaccacgaca ctgcaagttt ggaccgccta tcaggagagt gatttgacta
     4261 gatttgtaag cttatcctat tcgagtgaag attgtgcaga gattgattgt ctcggcgtaa
     4321 aaaagcttat caaggtagaa aaattgggag ccaattgctt gctactttag agagtgaagc
     4381 tcgtaaaaaa gttggttatc tgcaggtcaa aacagtggca gaaggttcta ataaagatta
     4441 tgatcgaaca aatgactttt atcgaggtct tggctttaaa aagttagaga tttttcctca
     4501 actatggaat ccgcaaaatc cttgtcagat tttgattaaa aagcttgaat aatattactt
     4561 gacatctatt ctcagagtgc catactgtaa gtgtaatcgc cgatttagct cagttggtag
     4621 agcaaggcac tcgtaaagcc taggttatag gtagataaac gactgaggag ttgaaaaaat
     4681 agataggtag aagataaccg ttaagcctta ttcttagcgg ttatttatat tgtttaatag
     4741 cgctgatatt tcatcaatta tgcctgtttt cgtgtttctg gtagttgttc aagtttattg
     4801 ctactatttt tgatggtatg aatgtgctta taatgtatcc cggttaacga aagttttgga
     4861 cttatactct t
//
LOCUS       DAVBEO010000081         4552 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 009
            SAMEA1678075-rid20185393.denovo.081, whole genome shotgun sequence.
ACCESSION   DAVBEO010000081 DAVBEO010000000
VERSION     DAVBEO010000081.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678075
            Sequence Read Archive: ERR226392
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4552)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4552)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980207.1
            Genome Coverage       :: 150x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:50:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 72 of 147
            Pseudo Genes (incomplete)         :: 72 of 147
            Pseudo Genes (internal stop)      :: 42 of 147
            Pseudo Genes (multiple problems)  :: 32 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4552
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678075-rid20185393.denovo.081"
                     /strain="KS 009"
                     /db_xref="taxon:1313"
     gene            complement(112..549)
                     /locus_tag="VQ543_002044"
     CDS             complement(112..549)
                     /locus_tag="VQ543_002044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-binding protein"
                     /protein_id="HET2612702.1"
                     /translation="MSQEFINPSDGVIRQYLATSKTLAVVGLSDREETTSNRVTKEMQ
                     ARGYKIIPVNPKAAGGEILGEKAYASLAEIPFPVDIVNVYRRSEFLPDVARDFLKADA
                     KIFWAQLGLESLEAKEILRDGGCDDIVMNRCIKREHTRLIEEA"
     gene            complement(634..3267)
                     /gene="polA"
                     /locus_tag="VQ543_002045"
     CDS             complement(634..3267)
                     /gene="polA"
                     /locus_tag="VQ543_002045"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014932012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase I"
                     /protein_id="HET2612703.1"
                     /translation="MDKKKLLLIDGSSVAFRAFFALYQQLDRFKNAAGLHTNAIYGFQ
                     LMLSHLLERVEPSHILVAFDAGKTTFRTEMYADYKGGRAKTPDEFREQFPFIRELLDH
                     MGIRHYELAQYEADDIIGTLDKLAEQDGFDITIVSGDKDLIQLTDEHTVVEISKKGVA
                     EFEAFTPDYLMEEMGLTPAQFIDLKALMGDKSDNIPGVTKVGEKTGIKLLLEHGSLEG
                     IYENIDGMKTSKMKENLINDKEQAFLSKTLATIDTKAPIAIGLEDLVYSGPDVENLGK
                     FYDEMGFKQLKQALNVSSADVAEGLDFTIVDQISQDMLSEESIFHFELFGENYHTDNL
                     VGFAWSCGDKLYATDKLELLQDPIFKDFLEKTSLRVYDFKKVKVLLQRFGVDLQAPAF
                     DIRLAKYLLSTVEDNEIATIASLYGQTYLVDDETFYGKGVKKAIPEREKFLEHLACKL
                     AVLVETEPILLEKLSENGQLELLYDMEQPLAFVLAKMEIAGIVVKKETLLEMQAENEL
                     VIEKLTQEIYELAGEEFNVNSPKQLGVLLFEKLGLPLEYTKKTKTGYSTAVDVLERLA
                     PIAPIVKKILDYRQIAKIQSTYVIGLQDWILADGKIHTRYMQDLTQTGRLSSVDPNLQ
                     NIPARLEQGRLIRKAFVPEWEDSVLLSSDYSQIELRVLAHISKDEHLIKAFQEGADIH
                     TSTAMRVFGIERPDNVTANDRRNAKAVNFGVVYGISDFGLSNNLGISRKEAKAYIDTY
                     FERFPGIKNYMDEVVREARDKGYVETLFKRRRELPDINSRNFNIRGFAERTAINSPIQ
                     GSAADILKIAMIQLDKALVAGGYQTKMLLQVHDEIVLEVPKSELVEMKKLVKQTMEEA
                     IQLSVPLIADENEGATWYEAK"
     gene            3520..3873
                     /locus_tag="VQ543_002046"
     CDS             3520..3873
                     /locus_tag="VQ543_002046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001811778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family transposase"
                     /protein_id="HET2612704.1"
                     /translation="MILRHLGISPTNDLVAKKIFSNPEITCQFIRDMLDLPAKNVTIL
                     EGSNIHVLPSMPYSAQDFYTSIDVLAELDNGTQVIIEIQVHHQNFFINHLWAYLCSQV
                     NQNLEKIRQREGDTH"
     gene            4088..4204
                     /locus_tag="VQ543_002047"
     CDS             4088..4204
                     /locus_tag="VQ543_002047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000233180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="damage-inducible protein CinA"
                     /protein_id="HET2612705.1"
                     /translation="MVGVFRQQALYPATATSHYPSKSTAGLQELVRGGQENV"
     gene            4197..4430
                     /locus_tag="VQ543_002048"
     CDS             4197..4430
                     /locus_tag="VQ543_002048"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2612706.1"
                     /translation="MFSQLHMREEQVLLAQDYALETARAEGLEQGLERGKVEGRAERK
                     LFAFLDIVRQGLLTSEVASQQLGMSVSEFEALL"
BASE COUNT         1385 a         1096 c          837 g         1234 t
ORIGIN      
        1 gtatctacaa cctcaaaaca gtgttttgag cagcccgcga ctagtttcct agtttgctct
       61 ttgattttca ttgagtataa cacaaaaggt agcccatcag ctaccttttt cttatgcttc
      121 ctcaatcaag cgagtatgtt ctctcttgat acagcgattc atcacgatat catcacatcc
      181 accatcacgc aaaatctctt tcgcttctaa actttcaagt cctagctgtg cccaaaaaat
      241 cttggcatca gctttgagaa aatcacgcgc cacatcgggc agaaattcac tgcgacgata
      301 aacattgaca atatctacag gaaaaggaat ttcagcgagg ctagcataag ccttttcacc
      361 caagatttcg ccacctgccg ccttgggatt gactgggatg attttatagc cccgagcctg
      421 catttccttt gtcactcgat tgctggttgt ttcttcacgg tcagacaaac ccaccacagc
      481 aagggtttta ctcgttgcga gatactgacg aatcacgcca tcacttggat tgataaattc
      541 ttgactcata gaaaacctcc tttttcatca gtatagcaca ttttgaaaag gtttgcagaa
      601 ttctactaca aaaaaggagg actagccccc tttttattta gcctcgtacc aggttgcccc
      661 ttcattctca tctgcgataa gaggaacact gagttgaatg gcttcttcca tggtttgttt
      721 caccaatttt ttcatctcta ccaattcaga tttaggcact tcaaggacga tttcatcgtg
      781 cacttgtaac agcatcttag tctgataacc acctgcaacc aaggctttat ccagctgaat
      841 catggcaatc ttgagaatat ctgctgccga accctggata ggtgagttga tagcagttcg
      901 ctccgcaaaa ccacgaatat tgaagttgcg cgaattgata tctggcaact cacggcgacg
      961 cttaaagagg gtctctacat agcccttatc acgcgcctcc cgcaccactt catccatgta
     1021 gtttttaata cctggaaaac gttcaaagta ggtatcaatg taggctttgg cttccttacg
     1081 actaattccc aaattattag acaagccaaa gtctgaaatc ccataaacca ctccaaagtt
     1141 aactgccttg gcattgcgac gatcatttgc agtcacatta tcaggacgct caatgccaaa
     1201 gacccgcatg gctgtcgaag tatggatatc tgccccctct tggaaggcct taatcaagtg
     1261 ctcatcctta gaaatatgcg ccaaaacgcg caattcaatc tgtgaatagt cagagctgag
     1321 tagcacacta tcctcccact ctggcacaaa agccttccga atcaagcgcc cttgttccaa
     1381 tcgggcagga atattttgca agtttggatc cacactagac aaacgcccgg tctgggtcaa
     1441 atcctgcata tagcgagtat gaatctttcc atcagccaaa atccagtcct gcaagccaat
     1501 tacataagta gattgaatct tagcaatttg acggtaatcc aggattttct taacaatcgg
     1561 agcaatagga gcgagacgct ccaacacatc cactgctgtc gaataacctg tcttggtttt
     1621 cttagtgtat tctagaggaa gtcccaattt ctcaaagaga agcacgccca actgcttagg
     1681 cgagttgaca ttaaactcct caccagccag ctcgtaaatc tcttgagtca gtttttcaat
     1741 gacaagctca ttttcagcct gcatctcaag caaggtctct ttcttgacca caatcccagc
     1801 aatttccatc ttggcaagaa caaaagccag aggttgctcc atatcataaa gaagctctaa
     1861 ttgcccattt tcgctgagtt tttcaagtaa aataggctct gtttctacca aaacagcaag
     1921 tttacaagct aagtgttcca agaatttctc acgttcagga atggcctttt taacaccctt
     1981 accgtagaaa gtttcatcat caaccaagta agtctgacca taaagactag cgatggtcgc
     2041 aatttcattg tcctccacag tcgaaaggag gtatttagcc aaacggatgt caaaagcagg
     2101 cgcctgcaaa tccacaccaa aacgttgcaa aagaacttta accttcttaa agtcataaac
     2161 tctcagagat gttttttcta agaaatcctt gaaaatcggg tcttgcaaca gctcaagctt
     2221 gtctgtggca tagagcttat ccccacaaga ccaggcaaat ccaaccaaat tatccgtatg
     2281 ataattctca ccaaaaagct caaagtggaa gatagactct tcactcagca tatcttgact
     2341 gatttggtca acaatagtaa aatccaaacc ctcagccaca tcagctgacg acacatttaa
     2401 agcctgcttg agctgtttga atcccatctc atcgtaaaat ttcccaagat tttcaacatc
     2461 tggaccacta tagaccaagt cctctaaacc aatcgcaatc ggtgccttgg tatcaatggt
     2521 cgctagtgtt ttagacaaaa aggcctgttc cttgtcattg atgagatttt ccttcatctt
     2581 agaagtcttc attccatcaa tattttcata aatcccctca agcgaaccat gctccagcaa
     2641 gagcttaata cccgtctttt caccgacttt ggtcacccca gggatattat ccgacttatc
     2701 acccatgagc gccttgagat cgataaactg agctggtgtg aggcccattt cttccatgag
     2761 gtaatctggc gtaaaggcct caaactcagc cacacctttc ttggaaattt caaccaccgt
     2821 atgctcatcc gtcagctgaa tcaaatcctt gtccccactg acaatggtaa tatcaaaacc
     2881 atcctgctct gctagcttat ccaacgtccc aatgatgtca tccgcctcat actgagccag
     2941 ctcatagtga cgaatcccca tatgatccag caactcacga atgaaaggaa attgctcacg
     3001 aaactcatca ggagtcttgg cccgaccacc cttatagtcc gcatacatct ctgtccggaa
     3061 ggtcgtcttt cccgcatcaa aagccaccaa aatatgactc ggctcaaccc gctccaacaa
     3121 atgactcaac atcaactgaa aaccataaat cgcattggta tgcaaaccag ccgcattctt
     3181 aaaacggtcc aactgctgat acagcgcaaa aaacgcccga aaagctacag aagacccatc
     3241 aatcaataat aattttttct tatccataca cccattataa aggaaagaat caaaaaatac
     3301 cattgggaag agctagagca agtatttttc aaactttttc cgaataaata gatagagcca
     3361 gagaatttag taaacctaga tttaaaaatg tgctataata tagtatattg aatctataat
     3421 agtacacctt gactgctaaa atatttctat aaattaattt gactttcctg atagagttgt
     3481 tcacatctta tttcaattca ctatagaagg aggaaaagga tgattctcag acatctggga
     3541 attagcccga ccaatgactt ggttgctaag aaaattttca gcaacccaga aatcacttgt
     3601 caatttatcc gcgatatgct ggacttgcca gccaaaaatg tgactatttt ggagggaagt
     3661 aacattcatg tcttgccttc catgccctac tcagcgcagg atttttatac cagtatagac
     3721 gtcttggcgg agttggataa cggtactcaa gtaattattg agattcaagt ccatcatcag
     3781 aattttttca tcaatcactt gtgggcttac ctgtgcagtc aggttaatca aaatcttgaa
     3841 aaaattcgtc agcgagaagg tgatactcac tagatctaca aacacatcgc tcctgtttac
     3901 gtcattgcta tcgtggatag taattatttc tcagatgacc tggcttttca tagctttagt
     3961 atgcgcgaag acacaacagg tgaggtattg gcgattacca acaatggaca ggaaaaccat
     4021 ctggttaaga tggcattctt ggaattaaaa aatacagaga aaccagcaaa gacaaggttc
     4081 gcaagccatg gttggagttt ttcggcaaca agccctttac ccagcaaccg caacgagcca
     4141 ttacccaagc aaatcaactg ctggactaca agagctggtc cgaggaggac aggaaaatgt
     4201 ttagtcaact acatatgcga gaagaacaag tcttgttagc acaggactat gccttggaaa
     4261 ctgctagggc tgaaggcctt gaacaaggac tagagcgtgg gaaagttgaa ggaagggcag
     4321 aaaggaaact ttttgccttc ctagacatag tacgccaagg tcttctgact tctgaggttg
     4381 ccagccagca attaggtatg tcagtatctg aatttgaggc actgttgtaa aatggctcca
     4441 taatatccat agtgggtaaa tcccctatgg atattatgga gcctattttt gtgtagaaaa
     4501 aaagtcccat atgacctata atgaaaagcg acaaaacaac tcattaaaaa ga
//
LOCUS       DAVBEO010000082         4550 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 009
            SAMEA1678075-rid20185393.denovo.082, whole genome shotgun sequence.
ACCESSION   DAVBEO010000082 DAVBEO010000000
VERSION     DAVBEO010000082.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678075
            Sequence Read Archive: ERR226392
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4550)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4550)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980207.1
            Genome Coverage       :: 150x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:50:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 72 of 147
            Pseudo Genes (incomplete)         :: 72 of 147
            Pseudo Genes (internal stop)      :: 42 of 147
            Pseudo Genes (multiple problems)  :: 32 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4550
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678075-rid20185393.denovo.082"
                     /strain="KS 009"
                     /db_xref="taxon:1313"
     gene            <1..141
                     /locus_tag="VQ543_002049"
     CDS             <1..141
                     /locus_tag="VQ543_002049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET2612707.1"
                     /translation="LLPLPPYSPEYNPIEKTWAHIKKHLKKVLPSCNTFYEALLSCSC
                     FN"
     gene            complement(134..307)
                     /locus_tag="VQ543_002050"
     CDS             complement(134..307)
                     /locus_tag="VQ543_002050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001022221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteinase"
                     /protein_id="HET2612708.1"
                     /translation="MNIKKRVLSAGLTFASVLLLAACGQSGSDTKTYSSTFSGNPTTF
                     NYLLDYYTDNIVN"
     gene            complement(465..2072)
                     /locus_tag="VQ543_002051"
     CDS             complement(465..2072)
                     /locus_tag="VQ543_002051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HET2612709.1"
                     /translation="MQEKWWHNAVVYQVYPKSFMDSNGDGIGDLPGITSKLDYLAKLG
                     ITAIWLSPVYDSPMDDNGYDIADYQAIAAIFGTMEDMDQLIAEAKKRDIRIIMDLVVN
                     HTSDEHAWFVEACENPNSPERDYYIWRDEPNDLDSIFSGSAWEYDEKSGQYYLHFFSK
                     KQPDLNWENEKLRQKIYEMMNFWIDKGIGGFRMDVIDMIGKIPDEKVVNNGPMLHPYL
                     KEMNQATFGDKDLLTVGETWGATPEIAKLYSDPKGQELSMVFQFEHIGLQYQEGQPKW
                     HYQKELNIAKLKEIFNKWQTELGVEDGWNSLFWNNHDLPRIVSIWGNDQEYREKSAKA
                     FAILLHLMRGTPYIYQGEEIGMTNYPFETLDQVEDIESLNYAREALEKGVPIEEIMDS
                     IRVIGRDNARTPMQWDESKNAGFSTGQPWLAVNPNYEMINVQEALANPDSIFYTYQKL
                     VQIRKENSWLVRADFELLDTADKVFAYIRKDGDRRFLVVANLSNEEQDLTVEGKVKSV
                     LIENTLAQEVFEKQILVPWDAFCVELL"
     gene            2225..3709
                     /locus_tag="VQ543_002052"
     CDS             2225..3709
                     /locus_tag="VQ543_002052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008535024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1846 domain-containing protein"
                     /protein_id="HET2612710.1"
                     /translation="MKKQAFSSEQYLNLQRDHILERINQFDGKLYLEFGGKMLEDFHA
                     ARVLPGYEPDNKIKLLQELKEQVEVVIAINASNIEHSKARGDLGISYDQEVLRLIDKF
                     NELGIFVGSVVITQYAGQPAADAFLNQLEKNGIDSYLHYPIKGYPTDMDHIISPEGMG
                     KNDYIKTSRNLIVVTAPGPGSGKLATCMSNMYHDQINGIKSGYAKFETFPVWNLPLHH
                     PVNLAYEAATADLDDVNMIDPFHLQTYGETTVNYNRDIEIFPVLKRMLERILGKSPYA
                     SPTDMGVNMVGFAITDDEAAVEASKQEIIRRYYQTVLDFKAEKVGEAAVKKIELLMND
                     LGISPADRKVAVVARQKAEETGGPALALELPNGDIVTGKNSELFGPTAAALINAIKKS
                     ADIAKEVKLIEPEVVKPIQGLKIDHLGSRNPRLHSNEILIALAITATENPDAARAMEE
                     LGNLKGSEAHSTIILTDEDKNVLRKLGINVTFDPYYQYDRLYRK"
     gene            3804..4286
                     /locus_tag="VQ543_002053"
     CDS             3804..4286
                     /locus_tag="VQ543_002053"
                     /EC_number="4.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002893508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteine lyase"
                     /protein_id="HET2612711.1"
                     /translation="MSKEVIVESFELDHTIVKAPYVRLIGEETGPKGDIISNYDIRLV
                     QPNEDSIPTAGLHTIEHLLAKLIRTRIDGMIDCSPFGCRTGFHMIMWGRHTSAKIAAV
                     IKDSLKEIAETTTWEDVPGTTIESCGNYKDHSLFSAKEWAKLILEQGISDDAFERHVI
                     "
BASE COUNT         1317 a         1047 c          860 g         1326 t
ORIGIN      
        1 cttttacctc ttcctcccta ctcacctgag tacaatccta ttgagaaaac atgggctcat
       61 atcaaaaagc acctcaaaaa ggtattacca agttgcaata ccttttatga ggctcttttg
      121 tcttgttctt gtttcaattg actatattat cagtgtaata gtctaataga tagttaaatg
      181 tagttggatt tccactaaag gttgatgagt aagtttttgt atctgaacct gattggccgc
      241 aagcagctaa aagcaaaaca gatgcaaaag tcaggcctgc actaaggaca cgcttcttta
      301 tgttcatctt ctttctcctt aatagtggga atttgtaaag ttaattgaat ttcgagaatg
      361 aaagtttata aaccttggtt ataaaaaaca aaggatttct gcttttatac agtcctccct
      421 tgtttttata tgatttcaat tttaaatttt tctgcaaaaa atatttatag taattccaca
      481 cagaaagcat cccatggaac taagatttgt ttttcaaaga cttcttgagc tagggtgttt
      541 tcaatcaaga cagatttgac ttttccttct actgtcaagt cttgctcttc attggacaag
      601 ttagccacaa ctaggaagcg acggtcgcca tccttacgta tataagcaaa gaccttatca
      661 gccgtatcaa gcaattcaaa gtcagctcga actagccagc tattctcctt gcgaatttgg
      721 accagtttct gataggtata gaaaatagaa tctggatttg ccagcgcttc ttggacattg
      781 atcatctcgt aatttggatt aaccgccaac caaggttgac ctgttgagaa accagcgttt
      841 ttgctctcgt cccattgcat aggggtacgg gcattgtcac gtccaataac acggatactg
      901 tccatgattt cttcaatcgg aacacctttt tcaagagcct cacgcgcata gttgagagat
      961 tcaatatctt ctacttgatc cagtgtttca aacggatagt tggtcatccc aatctcctca
     1021 ccttggtaga tataaggagt tcctctcata agatgaagca agattgcaaa ggctttggca
     1081 gatttttcgc ggtattcttg gtcatttccc cagattgaga caatacgagg gaggtcatgg
     1141 ttgttccaga agagggaatt ccagccgtcc tcaactccta actctgtctg ccatttgttg
     1201 aagatttctt ttaacttagc gatattcagc tctttttgat agtgccattt aggctgacct
     1261 tcctgatact gaagaccgat atgttcaaac tggaagacca tagacaattc ttgccccttt
     1321 ggatcagagt agagcttggc aatctctggc gttgctcccc aagtctcccc tactgtcaag
     1381 agatccttat ctccaaaggt cgcctgattc atttccttga gatagggatg gagcatagga
     1441 ccattattga ctaccttctc gtcaggaatt ttgccaatca tgtcaataac atccatacgg
     1501 aaaccaccaa tacccttatc aatccagaag ttcatcatct cataaatttt ctggcgaagt
     1561 ttttcatttt cccagttgag atccggctgt ttcttgctga aaaagtggag atagtattga
     1621 cctgactttt catcgtattc ccaagcagac ccactaaaga tagaatctaa atcgttaggc
     1681 tcatcccgcc agatatagta gtctcgctca gggctattag gattttcaca ggcctctaca
     1741 aaccaggcat gctcatccga ggtatgattg accaccaagt ccatgatgat acggatatca
     1801 cgcttcttag cttctgcaat cagctgatcc atgtcctcca tggttccaaa aatagccgca
     1861 atcgcttgat aatcagcaat atcgtagcca ttatcatcca tagggctgtc ataaacggga
     1921 gaaagccaaa ttgctgtgat tcctagcttg gctagatagt ccaacttact ggtaattcct
     1981 ggcaaatcgc caattccatc tccattacta tccataaaac tctttggata gacttgatag
     2041 actacggcat tatgccacca tttttcttgc atctgtttac ctcattattt tcataatcta
     2101 tagtctatga tagcactttt taaaattttg tgcaagcgtt tgcttaatct ttttaatttc
     2161 ttttttagct ccgtagtttc ctaacttcca attttttatt ataatagagt ccagaggtaa
     2221 aaaaatgaaa aaacaagctt ttagttctga acagtatttg aatttacaac gcgaccatat
     2281 tttggagcgc attaaccaat ttgacggcaa gctctactta gagtttggcg gtaaaatgtt
     2341 agaagatttc cacgctgctc gtgtccttcc tggttatgaa cctgacaaca aaatcaagct
     2401 cttgcaagaa ttgaaagagc aggttgaggt tgtgattgcc attaatgcta gcaacattga
     2461 acattccaaa gcacgtggcg acttgggcat ttcttatgac caagaagttc ttcgtttgat
     2521 tgacaaattc aatgaattag ggatttttgt tggttccgtt gtcattacac aatacgctgg
     2581 ccaacccgct gcagatgcct tcctcaacca acttgagaaa aacggaattg attcttatct
     2641 tcattatcca atcaaaggat atccgacgga tatggatcac atcatttccc cagaaggcat
     2701 gggcaaaaac gactacatca aaaccagtcg caacttgatt gtcgtaaccg ctcctggacc
     2761 cggttctgga aaattggcaa cgtgtatgtc caatatgtac cacgaccaaa tcaatggcat
     2821 caagtctggc tacgctaaat ttgaaacctt ccctgtttgg aatcttcccc ttcatcatcc
     2881 agttaacttg gcttatgaag ctgccacagc tgaccttgat gatgtcaaca tgattgaccc
     2941 cttccatctt caaacctatg gagaaaccac tgtcaactac aaccgtgata tcgaaatctt
     3001 cccagtgctc aagcgcatgt tggaacgtat tctcggaaaa tcaccatacg cttcaccgac
     3061 agatatgggt gtcaacatgg ttggtttcgc tattacagat gacgaggctg ctgtcgaagc
     3121 ttctaaacaa gaaatcatcc gccgttacta tcaaacagtt cttgacttca aagctgaaaa
     3181 agttggcgaa gctgccgtca agaaaattga gttgctcatg aacgacctcg gtatctcacc
     3241 tgcagaccgt aaggttgctg tcgttgcgcg ccaaaaagca gaagaaactg gcggaccagc
     3301 cctagctctt gaattaccaa atggtgacat tgtcactggt aaaaactcag aactctttgg
     3361 ccctacagcc gctgccttga tcaacgccat caaaaaatca gctgacatcg ctaaagaagt
     3421 aaaactaatc gagcctgaag ttgttaagcc aatccaagga cttaaaatcg atcatctcgg
     3481 tagccgcaat ccacgccttc attcaaatga aatcctgatt gcacttgcta tcacagctac
     3541 agaaaatcct gatgctgccc gcgctatgga agaactcggc aacctcaaag gaagcgaagc
     3601 ccactcaacc atcatcttga ctgatgaaga caagaatgtc cttcgtaaac tgggtatcaa
     3661 cgtaaccttt gacccatact accaatacga ccgcttatat cgtaagtaaa gatttcaacc
     3721 tctccagcct cggagaggtt ttctctctgt ctcaggagca agctttatga tataatgaga
     3781 gaagaaaact gaaaggattt accatgtcaa aagaagttat tgtcgaaagt tttgaacttg
     3841 accacaccat tgtcaaagca ccctatgttc gcttgattgg ggaagaaaca ggaccaaaag
     3901 gagacatcat ctccaattat gatattcgct tggtgcaacc aaacgaagac tctatcccta
     3961 ctgccggcct tcacactatc gagcacctct tagccaaact catccgtacc cgcattgacg
     4021 gcatgattga ctgttcacca tttggttgcc gcacaggctt ccacatgatt atgtggggac
     4081 gtcacaccag tgctaaaatc gcagctgtta tcaaggattc gctcaaggaa atcgctgaaa
     4141 ctactacttg ggaagatgtc ccagggacaa ccatcgaatc ttgcggaaac tacaaggacc
     4201 acagcctctt ctctgctaaa gaatgggcaa aactcatctt ggaacaaggg atttcagatg
     4261 atgcctttga acgtcatgtg atttaaaatc gagtagggga taatctctag cccctctcac
     4321 accaccgtac gtgccgttcg gcatacggcg gttcaactaa cttttaacgc atgtcgttca
     4381 aggtaataat ccaaacacga aaccaatcca cgtttttcaa ggactggttt tgatatagca
     4441 cgtttaagta ccgacttctg agctactata gtggattgaa actagaatag ttcacctctg
     4501 cttctaaaac attgttagaa atcgatttga ctatcctgat cgatttgttc
//
LOCUS       DAVBEO010000083         4438 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 009
            SAMEA1678075-rid20185393.denovo.083, whole genome shotgun sequence.
ACCESSION   DAVBEO010000083 DAVBEO010000000
VERSION     DAVBEO010000083.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678075
            Sequence Read Archive: ERR226392
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4438)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4438)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980207.1
            Genome Coverage       :: 150x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:50:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 72 of 147
            Pseudo Genes (incomplete)         :: 72 of 147
            Pseudo Genes (internal stop)      :: 42 of 147
            Pseudo Genes (multiple problems)  :: 32 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4438
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678075-rid20185393.denovo.083"
                     /strain="KS 009"
                     /db_xref="taxon:1313"
     gene            <1..119
                     /locus_tag="VQ543_002054"
     CDS             <1..119
                     /locus_tag="VQ543_002054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HET2612712.1"
                     /translation="QQGFTDRLVGYSSSIALVFTTLIGMISLVQRRVLKEDD"
     gene            121..966
                     /locus_tag="VQ543_002055"
     CDS             121..966
                     /locus_tag="VQ543_002055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000819520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HET2612713.1"
                     /translation="MKRFKPTTILEYILLTLLAGLFLFPMVWMVVSAMKPEADVYKNL
                     TSWQAFLPSLNPADWFKPYQEVFERFSIFTYLGNSIFYAGTFAIGSIIVNALAGFAFA
                     KVNFSGKKILFGFLLALLIIPVETVLIPQFTIINSLGLVNNRLAVIIPGLASVFNIYL
                     FRNFFIAIPEEILESAKMDGASIVRIFFRIMLPMSKPAVATVGVLSFISSWNDYIWPL
                     MVLTDSSKFSMQVAITTINTTQPVYINQVMAVLTISTIPLILVYVVAQKYIVQGLGGS
                     GTGIK"
     gene            976..2295
                     /locus_tag="VQ543_002056"
     CDS             976..2295
                     /locus_tag="VQ543_002056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32 protein"
                     /protein_id="HET2612714.1"
                     /translation="MINKTFTVEKANRFIAENKHLVNTQYKPEEHFSAEIGWINDPNG
                     FVYFRGEYHLFYQFYPYDSVWGPMHWGHAKSKDLVTWEHLPVALAPDQDYDRNGCFSG
                     SAIVKDDRLWLMYTGHIEEETGVRQVQNMAFSDDGIHFEKISQNPVATGSDLPDELIA
                     ADFRDPKLFEKDGRYYSVVAAKHKDNVGCIVLLGSDNLVEWQFESIFLKGGEHQGFMW
                     ECPDYFELDGKDCLIMSPMRYQREGDSYHNINSSLLFTGKVDWREKRFIPESVQEIDH
                     GQDFYAPQTLLDDQNRRILIAWMQTWGRTLPTHDQEHKWACAMTLPRILRLEDGKLRQ
                     FPVKKGQYQIQIDKDCHYHLGNDTDYLEFGYDSNAQQVYIDRSHLIQKILGEEEQDTS
                     RRYVDIEAKELEVVLDKNSIEIFVNQGEASLTATYYLTVPAELSRID"
     gene            complement(2503..2575)
                     /locus_tag="VQ543_002057"
     tRNA            complement(2503..2575)
                     /locus_tag="VQ543_002057"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(2540..2542),aa:Lys,seq:ctt)
     gene            complement(2839..4110)
                     /locus_tag="VQ543_002058"
     CDS             complement(2839..4110)
                     /locus_tag="VQ543_002058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001113185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication-associated recombination protein A"
                     /protein_id="HET2612715.1"
                     /translation="MPDNLALRMRPKTIDQVIGQEHLVGPGKIIRRMVEANRLSSMIL
                     YGPPGIGKTSIASAIAGTTKYAFRTFNATVDSKKRLQEISEEAKFSGGLVLLLDEIHR
                     LDKTKQDFLLPLLESGLVIMIGATTENPFFSVTPAIRSRVQIFELEPLSNQDVKEALQ
                     IALSNPERGFDFPIELDEDALDFIATSTNGDLRSAFNSLDLAVLSTPENDEGIRHITL
                     DIMENSLQRSYITMDKDGDGHYDVLSALQKSIRGSDVDASLHYAARLIEAGDLPSLAR
                     RLTVIAYEDIGLANPEAQIHTVTALDAAQRIGFPEARILIANVVIDLALSPKSNSAYV
                     AMDKALADLKTSGHLPIPRHLRDGHYSGSKELGNAQDYLYPHNYPGNWIKQDYLPEKI
                     RNHHYFQAEDTGKYERALAQRKEAIDRLRKI"
BASE COUNT         1294 a          809 c          976 g         1359 t
ORIGIN      
        1 atcaacaagg ttttactgat cgtcttgtag gatattctag ctcaatcgct ttagtattta
       61 caacgttaat tggtatgatt agcttagtac aacgtcgcgt tctgaaggag gatgactaag
      121 atgaaacgat ttaaaccaac aacaatctta gaatatattc tgttaacttt attggcagga
      181 ctcttccttt ttcctatggt ttggatggta gtttcagcta tgaagccaga agcggatgtt
      241 tataaaaatt tgactagttg gcaagccttc ttaccaagtt taaatcccgc tgattggttt
      301 aaaccttatc aggaagtatt tgagcgcttt agtattttta catatctagg gaacagcatt
      361 ttttatgctg gaacgtttgc tattggttct attattgtca atgcactggc cggtttcgct
      421 tttgcaaaag tcaatttttc aggtaagaaa attttatttg gtttcttact tgctttactt
      481 attattccag tggaaactgt gttaattcca caatttacca ttatcaattc cttaggtttg
      541 gtcaataatc gtcttgcagt tattattcca ggattggcga gtgtatttaa tatttactta
      601 tttaggaatt tctttattgc aattccagaa gagattcttg agtctgcaaa gatggacgga
      661 gcaagtatcg ttagaatttt ctttagaatt atgcttccaa tgtctaaacc tgcagttgct
      721 acagttggtg ttttatcatt tatttcaagc tggaatgatt atatctggcc attgatggtt
      781 ttgacagatt cttctaaatt ttcaatgcag gttgcaatta caactattaa tacaactcaa
      841 ccagtttata tcaatcaggt aatggctgta ttaactattt caacgattcc gttgattttg
      901 gtctatgtag tcgctcagaa atatattgtt caaggtctgg gtggttccgg aactggaata
      961 aaataggata tacttatgat aaataaaaca tttacagtag aaaaagccaa tcgttttata
     1021 gcagaaaata aacatctcgt taatactcaa tataagcctg aagaacattt ttcagctgag
     1081 attggttgga tcaatgatcc aaatggattt gtctattttc gtggagaata ccatctcttt
     1141 tatcaattct atccatatga tagtgtttgg gggcctatgc actggggaca tgctaaaagt
     1201 aaggacttgg tgacttggga gcacttgcca gtggcacttg ctcctgacca agattatgac
     1261 cgaaatggtt gtttctcagg ctctgccatt gtcaaggatg atcgcctctg gctcatgtac
     1321 actggacata tcgaagaaga aaccggtgtc cgccaagtgc aaaatatggc attttcagat
     1381 gacgggattc actttgaaaa gatttcccaa aatccagttg caactggatc agacttgcca
     1441 gatgagttga ttgctgctga tttccgtgat ccaaaactct ttgaaaaaga tggacgctat
     1501 tactccgtag tagctgccaa acacaaggat aatgtgggct gtatcgttct actagggtcc
     1561 gataacctag tagaatggca gttcgaatcc atctttttaa aaggaggaga acaccaaggc
     1621 tttatgtggg aatgcccaga ttacttcgag ttagatggga aagattgcct tattatgtca
     1681 cccatgcgtt atcagcgtga gggagactca tatcataaca tcaactcatc gcttttgttc
     1741 acgggtaagg tagattggag agaaaaacgt tttatcccag aatcagttca agaaattgat
     1801 catggccaag acttctatgc gcctcaaaca ttgttggacg atcaaaatcg tcgtatcctg
     1861 attgcttgga tgcagacatg ggggcgtacc cttccaaccc atgaccaaga acacaaatgg
     1921 gcatgtgcca tgactttacc tagaattcta agattggaag atggcaaact aagacaattc
     1981 cctgttaaaa aaggccaata tcaaatccaa atagataaag attgtcatta ccacttagga
     2041 aatgatacag attatcttga atttggttat gacagtaatg cgcagcaagt ttacattgat
     2101 cgtagccatc ttattcaaaa aattctaggt gaagaagaac aggacactag tcgacggtat
     2161 gtagatattg aagctaaaga attggaagtt gttctagata aaaattccat cgagattttt
     2221 gtcaatcaag gtgaagcaag cttgactgca acttattact taacggtgcc agctgagcta
     2281 tcacgaattg attaaaaatt aagttatttc tcctaaagaa aaagttctct ttctaaaata
     2341 gtggaaagag gactttttgt gttttgggta tataagctta gtttatggta tttgtaaaat
     2401 tggtgttgga ttatgattta agctagtttt ctaaagaatt tgaaaaaaat tttatttaag
     2461 caaaaaaacc ttggttccaa ggcttttcct gttgtattta gatgccccct acagggatcg
     2521 aacctgtgac ccacggatta agagtccgct gctctgccag ctgagctaag gaggcaaaga
     2581 aaaagctgta ttggtgccga aacttcacgg tttgtattga acccgcgcaa ttaagcaggt
     2641 gggcaactcg ctctaactga agctgtttcc gtgtgagacg gcctacatgc tgttagaaga
     2701 cttttgtttc cctaataata caaaaaatag tcggtcaaca cttaagtgtg aagtcgtaca
     2761 ccacagcgtt tctatactta tatgatacca ctttttcaaa aaaaatcaag aggaaagtgc
     2821 aattttttga aaaggatttc agatttttcg caaacgatcg atagcttcct ttctttgagc
     2881 caaagcccgt tcatatttac cagtatcttc tgcttggaaa tagtgatgat tacgaatttt
     2941 ttctggcaga tagtcttgct tgatccaatt tccaggatag ttgtgtggat agagatagtc
     3001 ttgggcattc cccagttcct tgcttccact gtagtgccca tcacgcaggt gtcgcggaat
     3061 aggcaagtgc cctgatgttt tgaggtcagc aagtgcctta tccatagcta cataggctga
     3121 gttggatttt ggagaaaggg ccaaatcaat cacgacattg gcaatgagaa tgcgggcttc
     3181 ggggaaacca atcctttgtg cagcatccag agcagtcacg gtatgaatct gggcctcagg
     3241 attggctaag ccaatatctt cataggcgat aacagtcaag cgacgagcga gactaggcag
     3301 atccccagcc tcaatcaagc gggcagcata gtggagactg gcatccacat ctgagccacg
     3361 gatagacttt tgcagggcag atagaacatc atagtgaccg tctccatcct tgtccatagt
     3421 gatgtagctt ctctgaagac tattttccat gatgtctaag gtgatgtggc gaatgccctc
     3481 gtcattctca ggggtagaga gaacagccaa gtccagtgag ttaaaggcag agcgaaggtc
     3541 tccgtttgta gaggttgcga tgaaatccag cgcatcctca tctagttcta ttggaaaatc
     3601 aaaaccacgt tcagggttac ttagagctat ctgcagggcc tctttgacgt cttggttaga
     3661 cagaggttcc aactcgaaaa tttgaacacg gctacgaatg gcaggagtga cagagaagaa
     3721 aggattttca gtcgttgctc caatcatgat gaccagtcca ctttccaaga gaggcaagag
     3781 gaagtcttgc ttggtcttat ctagtcgatg aatttcgtct agcaatagga cgagaccacc
     3841 agaaaattta gcttcttccg agatttcttg cagtcgcttt ttactatcaa ctgtcgcatt
     3901 gaaagttcga aaggcatact tggtcgttcc agcgatggca gaggcaatac tggttttgcc
     3961 gattccagga gggccatata gaatcatgga ggacaggcgg ttggcttcca ccatgcggcg
     4021 gatgattttt ccaggtccga ccagatgctc ctgaccgatg acctggtcga tggttttagg
     4081 gcgcatgcga agcgcgagat tgtctggcat agcagtcctt tctaacgtgg atttgagtag
     4141 aatgactcat ctactatatc ttactatgtc cattctagcc tattagttgt gatatttcaa
     4201 tggttttgta ataatcaggg agtgagatag aatctttttt actatttaat ttaatgagga
     4261 gaggtatcag catgagagat ttgattttcc ttaaagctca aaataggata gttgagccta
     4321 aagaagtgga agtgctgact tgagaaataa tattgctgaa tgtcattgta tgaactataa
     4381 tgaaaagaga ggtgataagc aatggaaatg atggaccaag tcaggaaatt ttgatttt
//
LOCUS       DAVBEO010000084         4275 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 009
            SAMEA1678075-rid20185393.denovo.084, whole genome shotgun sequence.
ACCESSION   DAVBEO010000084 DAVBEO010000000
VERSION     DAVBEO010000084.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678075
            Sequence Read Archive: ERR226392
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4275)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4275)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980207.1
            Genome Coverage       :: 150x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:50:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 72 of 147
            Pseudo Genes (incomplete)         :: 72 of 147
            Pseudo Genes (internal stop)      :: 42 of 147
            Pseudo Genes (multiple problems)  :: 32 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4275
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678075-rid20185393.denovo.084"
                     /strain="KS 009"
                     /db_xref="taxon:1313"
     gene            <1..1261
                     /locus_tag="VQ543_002059"
     rRNA            <1..1261
                     /locus_tag="VQ543_002059"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
     gene            1313..1385
                     /locus_tag="VQ543_002060"
     tRNA            1313..1385
                     /locus_tag="VQ543_002060"
                     /product="tRNA-Ala"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1346..1348,aa:Ala,seq:tgc)
     gene            1510..>4275
                     /locus_tag="VQ543_002061"
     rRNA            1510..>4275
                     /locus_tag="VQ543_002061"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT         1171 a          888 c         1283 g          933 t
ORIGIN      
        1 atacatagcc gacctgagag ggtgatcggc cacactggga ctgagacacg gcccagactc
       61 ctacgggagg cagcagtagg gaatcttcgg caatggacgg aagtctgacc gagcaacgcc
      121 gcgtgagtga agaaggtttt cggatcgtaa agctctgttg taagagaaga acgagtgtga
      181 gagtggaaag ttcacactgt gacggtatct taccagaaag ggacggctaa ctacgtgcca
      241 gcagccgcgg taatacgtag gtcccgagcg ttgtccggat ttattgggcg taaagcgagc
      301 gcaggcggtt agataagtct gaagttaaag gctgtggctt aaccatagta ggctttggaa
      361 actgtttaac ttgagtgcaa gaggggagag tggaattcca tgtgtagcgg tgaaatgcgt
      421 agatatatgg aggaacaccg gtggcgaaag cggctctctg gcttgtaact gacgctgagg
      481 ctcgaaagcg tggggagcaa acaggattag ataccctggt agtccacgct gtaaacgatg
      541 agtgctaggt gttagaccct ttccggggtt tagtgccgta gctaacgcat taagcactcc
      601 gcctggggag tacgaccgca aggttgaaac tcaaaggaat tgacgggggc ccgcacaagc
      661 ggtggagcat gtggtttaat tcgaagcaac gcgaagaacc ttaccaggtc ttgacatccc
      721 tctgaccgct ctagagatag agttttcctt cgggacagag gtgacaggtg gtgcatggtt
      781 gtcgtcagct cgtgtcgtga gatgttgggt taagtcccgc aacgagcgca acccctattg
      841 ttagttgcca tcatttagtt gggcactcta gcgagactgc cggtaataaa ccggaggaag
      901 gtggggatga cgtcaaatca tcatgcccct tatgacctgg gctacacacg tgctacaatg
      961 gctggtacaa cgagtcgcaa gccggtgacg gcaagctaat ctcttaaagc cagtctcagt
     1021 tcggattgta ggctgcaact cgcctacatg aagtcggaat cgctagtaat cgcggatcag
     1081 cacgccgcgg tgaatacgtt cccgggcctt gtacacaccg cccgtcacac cacgagagtt
     1141 tgtaacaccc gaagtcggtg aggtaaccgt aaggagccag ccgcctaagg tgggatagat
     1201 gattggggtg aagtcgtaac aaggtagccg tatcggaagg tgcggctgga tcacctcctt
     1261 tctaaggata aggaactgcg cattggtctt gtttagtctt gagaggtctt gtggggcctt
     1321 agctcagctg ggagagcgcc tgctttgcac gcaggaggtc agcggttcga tcccgctagg
     1381 ctccattggt gagagatcac caagtaatgc acattgaaaa ttgaatatct atatcaaata
     1441 gtaacaagaa aataaaccga aaacgctgta gtattaataa gagtttatga ctgaaaggtc
     1501 agaaaataag gttaagttaa taagggcgca cggtggatgc cttggcacta ggagccgacg
     1561 aaggacgtga caaacgacga tatgccttgg gtagctgtaa gtaagcgatg atccagggat
     1621 ttccgaatgg gggaacccaa caggtagtac ctgttaccca catctgttaa ggatgtgagg
     1681 aggaagacgc agtgaactga aacatctaag tagctgcagg aagagaaagc aaaagcgatt
     1741 gccttagtag cggcgagcga aacggcagga gggcaaaccg aagagtttac tcttcggggt
     1801 tgtaggactg caatgtggac tcaaagatta tagaagaatg atttgggaag atcagccaaa
     1861 gagagtaata gcctcgtatt taaaatagtc tttgtaccta gcagtatcct gagtacggcg
     1921 ggacacgtga aatcccgtcg gaatctggga ggaccatctc ccaaccctaa atactcccta
     1981 gtgaccgata gtgaaccagt accgtgaggg aaaggtgaaa agcaccccgg gaggggagtg
     2041 aaatagaacc tgaaaccgtg tgcctacaac aagttcgagc ccgttaatgg gtgagagcgt
     2101 gccttttgta gaatgaaccg gcgagttacg ttatgatgcg aggttaagtt gaagagacgg
     2161 agccgtaggg aaaccgagtc tgaatagggc gccttagtat catgacgtag acccgaaacc
     2221 atgtgaccta cccatgagca ggttgaaggt gcggtaagac gcactggagg accgaaccag
     2281 ggcacgttga aaagtgcttg gatgacttgt gggtagcgga gaaattccaa acgaacttgg
     2341 agatagctgg ttctctccga aatagcttta gggctagcgt cgacattaga gattcttgga
     2401 ggtagagcac tgtttgggtg aggggtccat cccggattac caatctcaga taaactccga
     2461 atgccaatga attatggtcg gcagtcagac tgcgagtgct aagatccgta gtcgaaaggg
     2521 aaacagccca gaccaccagc taaggtccca aaataattgt taagtggaaa aggatgtggg
     2581 gttgcacaga caactaggat gttagcttag aagcagctat tcattcaaag agtgcgtaat
     2641 agctcactag tcgagtgacc ctgcgccgaa aatgtaccgg ggctaaaaca atttaccgaa
     2701 gctgtggata cctttatagg tatggtagga gagcgttcta tgtgtgatga aggtataccg
     2761 tgaggagtgc tggaacgcat agaagtgaga atgccggtat gagtagcgaa agacaggtga
     2821 gaatcctgtc caccgtaaga ctaaggtttc caggggaagg ctcgtccgcc ctgggttagt
     2881 cgggacctaa ggagagaccg aaaggtgtat ccgatggaca acaggttgat attcctgtac
     2941 tagagtatgt agtgatggag ggacgcagta ggctaactaa agcagacgat tggaagagtc
     3001 tgtctaagca gtgaggtgtg atatgagtca aatgcttata tctgtaacat tgagctgtga
     3061 tggggagcga agtttagtag cgaagttagt gacgtcacac tgccaagaaa agcttctagc
     3121 gtttaaacat actctacccg taccgcaaac cgacacaggt agtcgaggcg agtagcctca
     3181 ggtgagcgag agaactctcg ttaaggaact cggcaaaatg accccgtaac ttcgggagaa
     3241 ggggtgctga ctttaagtca gccgcagtga ataggcccaa gcaactgttt atcaaaaaca
     3301 cagctctctg ctaaatcgta agatgatgta tagggggtga cgcctgcccg gtgctggaag
     3361 gttaagagga gtgcttagcg taagcgaagg tatgaattga agccccagta aacggcggcc
     3421 gtaactataa cggtcctaag gtagcgaaat tccttgtcgg gtaagttccg acccgcacga
     3481 aaggcgtaat gatttgggca ctgtctcaac gagagactcg gtgaaatttt agtacctgtg
     3541 aagatgcagg ttacccgcga caggacggaa agaccccatg gagctttact gcagtttgat
     3601 attgagtgtc tgtaccacat gtacaggata ggtaggagtc taagagatcg ggacgccagt
     3661 ttcgaaggag acgctgttgg gatactaccc ttgtgttatg gccactctaa cccagatagg
     3721 tgatccctat cggagacagt gtctgacggg cagtttgact ggggcggtcg cctcctaaaa
     3781 ggtaacggag gcgcccaaag gttccctcag aatggttgga aatcattcgc agagtgtaaa
     3841 ggtataaggg agcttgactg cgagagctac aactcgagca gggacgaaag tcgggcttag
     3901 tgatccggtg gttccgtatg gaagggccat cgctcaacgg ataaaagcta ccctggggat
     3961 aacaggctta tctcccccaa gagttcacat cgacggggag gtttggcacc tcgatgtcgg
     4021 ctcgtcgcat cctggggctg tagtcggtcc caagggttgg gctgttcgcc cattaaagcg
     4081 gcacgcgagc tgggttcaga acgtcgtgag acagttcggt ccctatccgt cgcgggcgta
     4141 ggaaatttga gaggatctgc tcctagtacg agaggaccag agtggactta ccgctggtgt
     4201 accagttgtc ttgccaaagg catcgctggg tagctatgta gggaagggat aaacgctgaa
     4261 agcatctaag tgtga
//
LOCUS       DAVBEO010000085         4245 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 009
            SAMEA1678075-rid20185393.denovo.085, whole genome shotgun sequence.
ACCESSION   DAVBEO010000085 DAVBEO010000000
VERSION     DAVBEO010000085.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678075
            Sequence Read Archive: ERR226392
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4245)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4245)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980207.1
            Genome Coverage       :: 150x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:50:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 72 of 147
            Pseudo Genes (incomplete)         :: 72 of 147
            Pseudo Genes (internal stop)      :: 42 of 147
            Pseudo Genes (multiple problems)  :: 32 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4245
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678075-rid20185393.denovo.085"
                     /strain="KS 009"
                     /db_xref="taxon:1313"
     gene            complement(<1..1288)
                     /locus_tag="VQ543_002062"
     CDS             complement(<1..1288)
                     /locus_tag="VQ543_002062"
                     /EC_number="6.1.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine--tRNA ligase"
                     /protein_id="HET2612716.1"
                     /translation="MKLQKPKGTQDILPAESAKWQYVEGFAREIFKRYNYAEVRTPIF
                     EHYEVISRSVGDTTDIVTKEMYDFYDKGDRHITLRPEGTAPVVRSYVENKLFAPEVQK
                     PSKFYYMGPMFRYERPQAGRLRQFHQIGVECFGSSNPATDVETIAMAAHFLKEIGIQG
                     VKLHLNTLGNPESRAAYRQALIDYLTPLKETLSKDSQRRLEENPLRVLDSKEKEDKVA
                     VENAPSILDFLDEESQAHFDAVRQMLENLGVDYIIDTNMVRGLDYYNHTIFEFITEIE
                     GNDLTVCAGGRYDGLVAYFGGPETAGFGFGLGVERLLLILEKQGVTLPIENALDVYIA
                     VLGEGANIKALELVQALRQQGFKAERDYLNRKLKAQFKSADVFAAKTLITLGESEVES
                     GQVTVKNNQTREEVQVSLETISQNFSEIFEKLGFYTQ"
     gene            complement(1366..2613)
                     /locus_tag="VQ543_002063"
     CDS             complement(1366..2613)
                     /locus_tag="VQ543_002063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter"
                     /protein_id="HET2612717.1"
                     /translation="MKLLFRNPAYRILTLSRFFNAFGVSIFNLVFIVYASTLSQASFA
                     VAMANIVMILPTLFTVFAGIRADYTRDKVKWMVYSGLFQAVLFFLAALVVQQASLFAF
                     SSLCLINVISDIISDFAGGLRMPLIKEKVAEDDLMEAYSFSQFITYISAIGGQAFGVW
                     LLALSVNNFSLVAGINACFFLVSATILFLGKSKLSLSMSSADGENLKNEKLSIKDQFL
                     TIYRNLRLVFLKSGQKNFGFMLFAVLLINSLGGALGGIYNIFFLSHSLLNFSYTEALF
                     INQFCVLVSVIISSLTGNDYFGKQSLPRLMMWETVGLSLVGLANLFNQVVLGLLFLFF
                     TLYVSGKVQPKISAMLMKNLAPEVLARTSNFLGLLFTLSIPVGTACFSLVAVWNIQLT
                     WMLFVGLSLLAIFLTILNLKNDI"
     gene            complement(2804..3654)
                     /gene="rgg"
                     /locus_tag="VQ543_002064"
                     /pseudo
     CDS             complement(2804..3654)
                     /gene="rgg"
                     /locus_tag="VQ543_002064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398326.1"
                     /note="Rgg, as the term is used in Streptococcus
                     pneumoniae, is the lone quorum-sensing system
                     transcriptional regulator related to proteins Rgg1, Rgg2,
                     Rgg3, and Rgg4 of Streptococcus pyogenes.; frameshifted;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="quorum-sensing system transcriptional regulator
                     Rgg"
     gene            3778..4119
                     /locus_tag="VQ543_002065"
     CDS             3778..4119
                     /locus_tag="VQ543_002065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003080443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HET2612718.1"
                     /translation="MRDDIKINDRALALQDQIIEKLEKVFDTDVELDVYNLGLIYEIN
                     LDETGLCKIVMTFTDTACDCAESLPIEIVAGLKQIEGIKDIKVEVTWSPAWKITRISR
                     YGRIALGLPPR"
BASE COUNT         1351 a          891 c          829 g         1174 t
ORIGIN      
        1 attgagtata aaatcctagt ttttcaaaga tttctgagaa gttttggctg attgtctcaa
       61 gtgacacttg cacttcttct cgggtttggt tgttcttgac cgtcacttgt ccgctttcga
      121 cttcgctctc tcctagggtg atgagggtct tagccgcaaa gacatcggct gacttgaact
      181 gagcttttag tttacggttg aggtaatcac gctctgcttt gaaaccttgt tggcgaagag
      241 cctgtaccaa ttccaaggcc ttgatatttg ccccttcgcc caagactgcg atatagacat
      301 ctagggcgtt ttcgataggg agggtcacac cttgcttttc aaggatgaga agcaggcgct
      361 ctacaccaag tccaaaacca aatccagcag tttcagggcc tccaaagtaa gcaaccaaac
      421 catcgtagcg accacccgca cagacggtca ggtcattgcc ctcaatctct gtgataaact
      481 cgaaaatggt gtggttgtag tagtccagac cacgcaccat attggtatcg atgatgtaat
      541 ctactccaag attttccaac atctgacgca cagcatcaaa atgagcttgg ctttcttcat
      601 caagaaagtc caagatagac ggcgcattct ctactgccac cttgtcttct ttttccttag
      661 agtccaagac acgaagagga ttttcctcca agcgacgttg gctatcctta gacaaggtct
      721 ccttgagcgg tgtcaaatag tcaatcaagg cttggcggta ggctgcacgg ctctcaggat
      781 ttccaagagt gttgaggtgc aatttgacac cttgaatacc gatttccttc aaaaaatggg
      841 ctgccatagc gattgtttcc acatcggtag ctggattgct agagccaaaa cactcaacac
      901 caatctggtg gaattggcgc aagcgccctg cctgtggacg ctcataacgg aacataggtc
      961 ccatgtagta gaacttgctt ggcttttgca cttctggggc gaaaagttta ttttccacat
     1021 aggaacggac aacgggtgca gttccttctg gacggagggt aatatgacgg tcacccttgt
     1081 cataaaaatc gtacatttcc ttggttacga tatccgttgt atctccgaca gagcgactga
     1141 taacctcgta atgctcaaaa ataggcgtgc gcacttctgc atagttgtag cgtttgaaaa
     1201 tctcacgggc aaagccctca acgtactgcc acttagcaga ctcagcaggt aaaatatcct
     1261 gcgttccttt tggtttttgt aatttcatag ggaatcctct ttaaacttaa tagtcttatt
     1321 ttaccataaa tagagggatt aaaacagtaa gaaaaaaatt aggatttaga tatcattttt
     1381 gagattaaga attgtcaaaa aaatagctag caaggaaaga ccaacaaata gcatccaagt
     1441 caactgtata ttccatacgg ctactagtga aaaacaagct gttcccacag gtatggataa
     1501 ggtaaacaat agacctaaaa aattactagt acgagctaga acctctggag ctagattttt
     1561 catgagcatg gcactaatct ttggttgaac tttaccagac acatacagag taaagaagag
     1621 aaatagcaaa ccaagcacga cttgattgaa taaattagcc aaaccaacta gactaagtcc
     1681 tacggtctcc cacatcatca atctaggcaa ggactgcttc ccaaaataat cattgcccgt
     1741 aaggctactg atgatgactg atactaaaac acagaattga ttgataaata gtgcctctgt
     1801 ataagaaaaa ttcaagagag aatggctcaa aaagaagata ttataaattc cacccaaagc
     1861 gccacccaag gaattaataa gcaagacagc aaagagcata aaaccaaagt ttttctgtcc
     1921 acttttaaga aaaacgagac gtaaatttcg gtaaattgtt aggaactggt ctttgataga
     1981 aagcttctca ttttttaagt tttcaccatc agcagatgac attgacaggc tcaatttgct
     2041 ttttcctaaa aagaggatag tggctgatac taggaaaaag caggcattga ttcccgcaac
     2101 gagagaaaaa ttgttgaccg atagagctaa gagccagact ccgaaagctt gaccaccaat
     2161 agctgaaata taggtgatga actgtgaaaa agaataagcc tccatcagat catcttcagc
     2221 tactttttcc ttaataagag gcatacgcag gccacctgca aaatcactga tgatatcact
     2281 aatgacattg atcaaacaca ggctagaaaa ggcaaagaga ctagcttgct gaacaactag
     2341 ggctgctaga aaaaatagaa ccgcctgaaa caaaccgcta tagaccatcc atttgacctt
     2401 gtccctcgtg taatctgccc gaatccctgc aaaaactgta aagagggtcg gaagaatcat
     2461 gacaatattc gccatagcaa cagcaaaaga tgcttgtgac aaggtcgatg catagacgat
     2521 aaagaccagg ttgaaaatcg aaacaccaaa agcattgaag aagcgtgata aagtcaaaat
     2581 tctataagct ggatttctaa acaatagttt catagataat ctccctcctt gttctaagtt
     2641 ctacatcaag aatagcttta gtatagcact tatgaatttg cgaaacgatt cttttgaata
     2701 tatgcaacaa acaaaatgag caaaaaaacg atagaacttt tgtaatgacc tgagagaggg
     2761 caacagttct atcgcttcaa attttttctt ggtttgcaga tattcaagaa tcgggagttt
     2821 ttctatagta ttcggcagat ttattacagc caagcatctc aaaaatacgg acagcatcct
     2881 ccatcttttt ctggccttcc ttgactctac cttgcttgct atcaaggaga ccttctgccc
     2941 acagataaac aattcggaaa taggtctcat tttccttgta gaaatgctct tcgataacac
     3001 gtttaaaata ataggcattg gtaaattctt cacactcaat actagctaaa aagccattca
     3061 atagtatagt atgaaaaagg tttcgattgc cagacatttc cattagaaaa tcggatttac
     3121 gtaccatttc tcgtacatat ctagtaaaaa gagaaacaga taaaaatgga gaactgactg
     3181 aaaataaatt gagttcatag attccccaga tctcggtaga aaacaaataa tcatgaagga
     3241 cttttccttc ctctgctgtt aagtctaccc tttcatctat gctcttcata taagacttga
     3301 taataatggc atttagaata tgtttctgtt tgttgtgaga atgggcatgc ttttatactc
     3361 cctgcgatat aagtcctcaa gaggtgctat attctttggt tccaagacat ctgtaatttc
     3421 ttttctcaac tcagaatctg tatcatactg gaaacctctt gccagaaaga ggatctcctc
     3481 cacactggca gatatatttt ccagagcaaa tagaaacttt tccaccgaaa gctcactctg
     3541 acctgtttca aaacgggaca acatagacgg cgaaaattgt cctccggttg cttgtctcag
     3601 tgagatattt cttgactctc gtaattgtct aaagactttt ccaatctgct ccatagactt
     3661 ccccttgatt ccgtattttc ttcattttat catatttttc agaaaattca tcaaaaactt
     3721 gccaaattgt cagaattatg agaaaataga ggatatttat cacgtggagg gactgctatg
     3781 agagacgata tcaaaatcaa tgaccgtgct ttggccttgc aagaccaaat tatcgaaaaa
     3841 ctagagaaag tttttgatac agatgtggaa ttggatgttt acaatctagg tctgatttat
     3901 gaaatcaatc tggatgaaac ggggctctgc aagattgtca tgaccttcac cgatactgcc
     3961 tgtgattgcg ccgaaagcct gcctattgaa atcgtggcag gtctgaaaca aatcgagggt
     4021 atcaaagata tcaaggttga agttacctgg tcgcctgctt ggaaaatcac acgaatcagt
     4081 cgctatggcc gtattgccct tggactacca cctcgttaag cagaccaatc acttttaaag
     4141 atgaaaaaag caagccgaaa atggcttgct ttttgatact caatgaaaat caaagggcaa
     4201 actagaaaac tagccgcagg ttgctcaaaa cactgttttg aagtt
//
LOCUS       DAVBEO010000086         4116 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 009
            SAMEA1678075-rid20185393.denovo.086, whole genome shotgun sequence.
ACCESSION   DAVBEO010000086 DAVBEO010000000
VERSION     DAVBEO010000086.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678075
            Sequence Read Archive: ERR226392
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4116)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4116)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980207.1
            Genome Coverage       :: 150x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:50:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 72 of 147
            Pseudo Genes (incomplete)         :: 72 of 147
            Pseudo Genes (internal stop)      :: 42 of 147
            Pseudo Genes (multiple problems)  :: 32 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4116
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678075-rid20185393.denovo.086"
                     /strain="KS 009"
                     /db_xref="taxon:1313"
     gene            <1..776
                     /locus_tag="VQ543_002066"
     CDS             <1..776
                     /locus_tag="VQ543_002066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000603792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2612719.1"
                     /translation="DYSIVEEKLDWQSKLSKIYPNVEFIKIEKLKLILLCKYRNQIID
                     LEDDKKRLLLLKLLYLTSKQFCYDEFKGAKFGCMSFFSHYQGYMSRLDSLDSDKFVSV
                     KQRIVSSISKLVEQYSDHIINLDRTLVDSLSDTLENQLFDDWDYILSEITTYSELLAK
                     SGLLYNSLDYKIDNVKKEVAKLSDFHQSLFKIEGFSDFFDSWQFQRYRSLVNQVYEIF
                     SMLQVSSVERTVLCGALSTIVFSKSNFNYQAFFEYLKDT"
     gene            805..1713
                     /locus_tag="VQ543_002067"
     CDS             805..1713
                     /locus_tag="VQ543_002067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000386786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2612720.1"
                     /translation="MDYVDVILDEYGSVFLIKDHIKLKINNLELYRYFSSFGMSHLQF
                     RKEELPGKLKQFDFEKNKSDSYFSKKSSLIDFIKRNYFYDIKLYSDNPKNPIESWKNK
                     TEKIKIAKSTEILWSEVANFSSISKSPYYCLLYNLKNTENYILIISKTYFSAIQKMVS
                     YNLNNYFELEDVCCKSIVSKRELIENSININKSKMKLLNVCEGSKGYTRRVFKYNNIF
                     VGQLEFHSNIIFSEIALNELSIVKLLDSVESVLSEQLFGKLNWDNLFVVLSDDFNDYL
                     DINESQKYYSNGSLRGLELGIFMGGV"
     gene            1715..3613
                     /locus_tag="VQ543_002068"
     CDS             1715..3613
                     /locus_tag="VQ543_002068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YcaO-like family protein"
                     /protein_id="HET2612721.1"
                     /translation="MRIIEIVDVEDQLLQLLSAHTNIDIRAQELSTLDPDSKVDLIIY
                     LKSRRDIENINNIIIKSPNRNIIVIISAFDIIYALYFPKSTFRPCLNCLLLKLKDNNP
                     EHNLLLFLKYGTLPSKHFNLDNRLKSNLILFNEKLDPKVEEYSIEGVNTTNFTFHFSC
                     SCENSGYDMSERMADILLGEGKKLSPKNYRLKKSEHLFDFTRYLDRNFGFFHHSYDEK
                     ISEYAPLHAVEINVDAGYESGWGRTFMTEAATKSAFLESLERYCNSRNRRYKKLIRGC
                     FSDLSKKYNTLNPVDFCLSNKEYRDSSYKFHDFDSEKNYDWIFGKNITTGKICLLPSQ
                     LVFYKDFSKSEENERFVYETSNGCALGSSIEEAIFYGILEIIERDNFLLTWYLKEEVK
                     QLSWESLPSRLRIINERLKEDNCELKLFNITKEVGIPVIWALYINHNENASIRSFSAA
                     GCHINPLSAIESAIFEVITSVPTFERLIEVRNKESFIEEIQNNFSLIRDIDDHILYHA
                     HADYKNKMPFLFKNNYSEYQNEFDENRIFNTYSHATLTSDLQALIKIIEKKFGDIYVV
                     NISDKVSEKFGLYCVKVLIPGLLNMSFGHSNRRVNIERIKNYVDYRGGNVNSITLNSI
                     NHLPHPFP"
     gene            3637..>4116
                     /locus_tag="VQ543_002069"
     CDS             3637..>4116
                     /locus_tag="VQ543_002069"
                     /inference="COORDINATES: protein motif:HMM:NF025394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiopeptide-type bacteriocin biosynthesis
                     protein"
                     /protein_id="HET2612722.1"
                     /translation="MKRDWKSKHLFYHDVQQFDKLVIYLSKFMDKLVNQNQIEKYFYI
                     RYWEGGPHIRLRYLVRDTQNFETIDSMINKYAYKFWENNPPMKLLNKTDYKKIYNESI
                     DNNGKMDRKLRKNATIENIAYIPEIERYGGEEALIVSEDLFCICSQVSTALLNVVDNY
                     "
BASE COUNT         1539 a          443 c          712 g         1422 t
ORIGIN      
        1 cagattactc aatagtggaa gaaaaattag attggcaaag taaattatct aaaatttatc
       61 cgaatgttga atttataaaa attgaaaaat taaaattgat tttgttgtgt aaatatagaa
      121 atcaaattat tgacttagag gatgataaaa aaagattgtt actattgaaa ttattatatt
      181 tgacttcaaa gcaattttgc tatgatgaat ttaaaggagc gaaatttgga tgtatgtcat
      241 ttttttcaca ttatcaaggt tatatgagca gattagattc actcgactca gataaatttg
      301 tttcggttaa acagaggatt gtttcctcta tttctaaatt agttgagcaa tattcagatc
      361 atattataaa tctggataga actttagttg attctctaag tgataccctt gagaatcagc
      421 tatttgatga ttgggattat atattaagcg aaataactac atatagcgaa ttattagcaa
      481 aatcaggatt gttatataat tcgctagact ataagattga taatgtaaaa aaagaagtgg
      541 ccaagctaag tgactttcac caatctttat ttaaaattga aggattttca gatttttttg
      601 atagttggca atttcaaaga tataggtctc tcgtgaacca agtttatgaa attttttcaa
      661 tgttacaagt aagtagtgta gaaagaactg tgttgtgcgg agctctaagt actattgtct
      721 ttagtaagtc aaattttaac tatcaagctt tttttgagta tctaaaagat acgtagaatt
      781 cgattttaaa ggaggctgaa atatatggat tatgtagatg taatattgga tgagtatggg
      841 agtgtttttc tgataaagga tcacataaaa ctaaaaatta ataatctaga actatatcgg
      901 tattttagta gctttggaat gagtcatctt caatttagaa aagaagagct tccaggaaaa
      961 ttaaagcagt ttgattttga aaaaaataaa agtgacagtt atttttctaa gaaaagtagt
     1021 ctgattgatt ttattaagag aaattatttt tatgatatta agttatattc tgataatccg
     1081 aaaaatccga tagagtcttg gaaaaataag acagaaaaaa ttaagattgc taaaagtaca
     1141 gaaattcttt ggagtgaagt agcaaatttt tcgtcaattt ctaaatctcc ttactattgc
     1201 ttgttatata atttaaagaa tactgaaaat tacatattga taatcagtaa gacatatttt
     1261 tcagccatcc aaaaaatggt ttcgtataat ctaaataatt attttgaatt agaagatgtt
     1321 tgttgtaaaa gcatagtgag caagcgagaa ttgatagaaa attcaattaa tattaacaaa
     1381 agcaaaatga aactgctaaa tgtttgcgaa ggtagtaaag gttacacaag aagagtattt
     1441 aagtacaata atatttttgt gggacaattg gaatttcact ctaacataat cttttcagaa
     1501 attgctttaa atgaattaag tattgttaag cttttagatt ctgttgaaag tgttttatct
     1561 gagcaactat ttggaaaatt aaattgggat aatttatttg ttgttttatc agatgatttt
     1621 aatgattatc tggatataaa tgaatctcaa aaatactact caaatggttc tttgagagga
     1681 ctggagcttg gaatctttat gggaggggtt taaaatgaga ataattgaaa ttgttgatgt
     1741 tgaggaccaa cttttacaac ttttaagtgc acataccaat attgatatta gagcacaaga
     1801 gttatcaaca cttgacccag attcaaaagt tgatttgatc atatacttga aatctcgacg
     1861 tgatattgaa aacataaata atattattat taaatcacct aacaggaata tcattgttat
     1921 aataagtgct tttgatatta tatatgcatt gtattttcca aaatcaacat ttagaccttg
     1981 tttgaactgt ctattattaa aacttaaaga taacaaccct gagcataatc tattattatt
     2041 cctgaaatac ggaacattac ctagtaaaca ttttaatctt gataataggt taaaatcaaa
     2101 tttaatacta tttaatgaga agttagaccc taaggtagag gagtatagta ttgagggggt
     2161 aaatactaca aattttactt tccattttag ttgtagctgt gaaaatagtg gttacgatat
     2221 gtcggaaaga atggcagata ttctacttgg tgaaggaaaa aaattatctc ctaaaaatta
     2281 tcgtttaaaa aagagtgagc atctattcga ttttactaga tatctagata gaaattttgg
     2341 attttttcat cattcatatg atgaaaaaat ctccgaatat gcgcctctcc atgcagtaga
     2401 gattaatgtt gatgctggtt acgagtcagg ctggggaagg acttttatga cagaggctgc
     2461 aacaaaatct gcttttttag agtcattaga gagatactgc aactctagaa atagacgcta
     2521 taaaaaatta attagagggt gtttttctga tttatctaaa aagtacaata cattaaatcc
     2581 tgttgatttt tgtctttcta ataaagaata tagagatagt tcctataaat ttcatgattt
     2641 tgattctgag aaaaattatg attggatatt tggtaaaaat ataactaccg gaaaaatttg
     2701 cttattgccc tcgcaactag tattttataa agactttagt aaaagcgaag aaaatgaaag
     2761 gtttgtttat gaaacatcaa atggatgtgc tttggggagt agtattgagg aagctatttt
     2821 ttatgggatt ttagagatta ttgaaagaga taatttttta cttacatggt atttaaaaga
     2881 agaagtaaaa caattatcat gggaatcttt accatctcgc ctacgtatta ttaatgaaag
     2941 actaaaagaa gataactgtg agctcaaact ttttaatata actaaagaag tgggcatacc
     3001 agtaatttgg gcattgtata taaatcataa tgaaaatgct agtattcgaa gtttttcagc
     3061 tgcaggctgt catattaatc ctttaagtgc aattgaatca gcaatttttg aagtaataac
     3121 ttctgtgcca acttttgaaa gattaattga agttagaaat aaagagtcat ttattgagga
     3181 aattcagaat aatttttctt taatacgaga tattgacgat catatattgt atcatgctca
     3241 tgcggattat aaaaataaaa tgcccttttt atttaaaaat aattatagtg aatatcaaaa
     3301 tgaatttgat gagaatagaa tttttaatac ttattcacat gcaacgctta catcagattt
     3361 acaggcacta ataaaaatta ttgaaaaaaa atttggagat atatatgtag tgaatataag
     3421 tgataaagtt tccgaaaaat ttggacttta ttgtgttaaa gtgttgattc ctggacttct
     3481 taatatgtca tttggacatt caaatcggcg tgtaaatata gagaggataa aaaattatgt
     3541 agattataga gggggaaatg taaatagtat tacattgaat tccataaacc atcttcccca
     3601 tccatttcca taagattata tataaaggaa taataaatga aaagagattg gaaatcaaag
     3661 catttatttt atcatgatgt tcaacaattt gataaattgg taatctattt atcaaaattt
     3721 atggataaat tagttaatca gaatcagatt gaaaaatatt tctatattcg ttattgggaa
     3781 ggggggcctc atattcgatt aagatatttg gtgagggata cacaaaattt tgaaacaatt
     3841 gatagtatga taaataagta tgcttataaa ttttgggaaa ataatcctcc aatgaagtta
     3901 ttaaataaga ccgattataa gaaaatttat aatgagagta ttgataacaa cggaaagatg
     3961 gatagaaaat tgaggaaaaa tgcgactatt gaaaacattg cctatatacc ggaaatagag
     4021 agatatggcg gggaagaagc tctgatagta agcgaagatc tattttgtat ctgtagtcag
     4081 gtttcaactg cgttacttaa tgtggtagat aactat
//
LOCUS       DAVBEO010000087         3589 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 009
            SAMEA1678075-rid20185393.denovo.087, whole genome shotgun sequence.
ACCESSION   DAVBEO010000087 DAVBEO010000000
VERSION     DAVBEO010000087.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678075
            Sequence Read Archive: ERR226392
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3589)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3589)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980207.1
            Genome Coverage       :: 150x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:50:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 72 of 147
            Pseudo Genes (incomplete)         :: 72 of 147
            Pseudo Genes (internal stop)      :: 42 of 147
            Pseudo Genes (multiple problems)  :: 32 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3589
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678075-rid20185393.denovo.087"
                     /strain="KS 009"
                     /db_xref="taxon:1313"
     gene            complement(1..396)
                     /locus_tag="VQ543_002070"
                     /pseudo
     CDS             complement(1..396)
                     /locus_tag="VQ543_002070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; internal stop; incomplete; missing
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            737..2083
                     /gene="gdhA"
                     /locus_tag="VQ543_002071"
     CDS             737..2083
                     /gene="gdhA"
                     /locus_tag="VQ543_002071"
                     /EC_number="1.4.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001858584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-specific glutamate dehydrogenase"
                     /protein_id="HET2612723.1"
                     /translation="MTSAKEYIQSVFETVKARNGHEAEFLQAVEEFFNTLEPVFEKHP
                     EYIEENILARITEPERVVSFRVPWVDRDGKIQVNRGYRVQFNSAVGPYKGGLRFHPTV
                     NQGILKFLGFEQIFKNVLTGLPIGGGKGGSDFDPKGKTDAEVMRFCQSFMTELQKHIG
                     PSLDVPAGDIGVGGREIGYLYGQYKRLNQFDAGVLTGKPLGFGGSLIRPEATGYGLVY
                     YTEEMLKANGNSFAGKKVVISGSGNVAQYALQKATELGATVISVSDSNGYVIDENGID
                     FDLLVDVKEKRRARLTEYAAEKATATYHEGTVWTYAGNYDIALPCATQNEINGEAAKR
                     LVAQGVICVSEGANMPSDLDAIKVYKENGIFYGPAKAANAGGVAVSALEMSQNSLRLS
                     WTREEVDGRLKDIMTNIFNTAKTTSETYGLDKDYLAGANIAAFENVANAMIAQGIV"
     gene            complement(2589..2759)
                     /locus_tag="VQ543_002072"
     CDS             complement(2589..2759)
                     /locus_tag="VQ543_002072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2612724.1"
                     /translation="MKKENEYVILTIASLGVMIGIVFAIFLDFPVEYGISLGLLNGIV
                     LGSLIVYKNNKN"
     gene            complement(2772..3350)
                     /locus_tag="VQ543_002073"
                     /pseudo
     CDS             complement(2772..3350)
                     /locus_tag="VQ543_002073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151458.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
     gene            complement(3367..>3589)
                     /locus_tag="VQ543_002074"
     CDS             complement(3367..>3589)
                     /locus_tag="VQ543_002074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET2612725.1"
                     /translation="QAQTPRKSSKLKPLTAEDKACNHVLSKERSKVENIFAKVKTLKM
                     FSTTYRNHRKRFGLRMNLIVGIINHELGF"
BASE COUNT         1109 a          664 c          606 g         1210 t
ORIGIN      
        1 tataagcctg aaataaggca tcaattgtaa caaattctcc tgcctctgca gccttcaaat
       61 ggcgggcaag aaaggctttc tcttcctcaa ctgtcatata tgcatggtta cgaccaccac
      121 gtgtttcttg aaggagagag tcgagtccga actcctcata ttttttacat ttcgccaaat
      181 cgttgtttga ttacagtcta tagtgtattg aatctataat agtacacctc tacttctaaa
      241 acattgttag aaatcgattt gactgtccta atcgatttgt cctgttcttg tttcatttta
      301 ctatagaacg atttgaaggc gtttatgata tttagctgta cgagagtctt ttaaaagtgt
      361 tttgatggct tggatttctt ctttagttga tttcatatca ctattatata atgatttttg
      421 attttagtct ggtataaata ttgctttcct ccaaaatggt cataatttta ctagcaaatc
      481 taacatatca cggataaatt aacaagtgat ttctgaattg ctaaacattt tcttttctta
      541 tagcatacca tactttaaga ttttgtcttt gagaaagata tttccaagaa aaacgttcgt
      601 ttttttatct attttcaaaa aaaccaaaaa ctgaattgaa agaattttta gaaaatttct
      661 gttttttctt tacagtgaaa aaaaattctg ctataatgtc ttatgtaata aaatatgaca
      721 ataaaaggag aacgatatga catctgctaa agaatatatc caaagcgtgt ttgaaactgt
      781 gaaagctcgt aacgggcacg aggctgaatt cctccaagct gttgaagaat ttttcaacac
      841 tttagaacct gtatttgaaa aacaccctga gtatatcgaa gaaaatatct tggcacgtat
      901 tactgagcct gagcgcgtgg tttctttccg tgttccttgg gttgaccgtg atggaaaaat
      961 tcaagtaaac cgtggttacc gtgttcaatt caactcagct gttggaccat acaaaggtgg
     1021 acttcgtttc cacccaactg taaaccaagg gatcttgaaa ttcctcggat ttgaacaaat
     1081 ctttaaaaat gtcttgactg gacttcctat cggtggaggt aaaggtggat cagacttcga
     1141 tcctaaaggt aaaacagatg ctgaagtgat gcgcttctgc caaagcttca tgactgaatt
     1201 gcaaaaacac atcggaccat cacttgacgt acctgctggt gatatcggtg ttggtggacg
     1261 tgaaattggt tacctttacg gtcaatacaa acgtcttaac caatttgatg ctggtgtctt
     1321 gactggtaaa cctcttggat ttggtggtag cttgattcgt ccagaagcaa ctggttacgg
     1381 tttggtttac tatactgaag aaatgctcaa agctaacggt aacagctttg ctggtaagaa
     1441 agtcgttatt tcaggttctg gtaacgttgc tcaatatgct cttcaaaaag caactgaact
     1501 cggtgcaact gttatttctg tttctgactc aaatggttat gtcatcgatg aaaatggtat
     1561 cgacttcgat cttttggttg atgttaaaga aaaacgtcgt gctcgtttga ctgagtatgc
     1621 agctgaaaaa gcaactgcaa cctaccacga aggtactgta tggacttacg ctggaaacta
     1681 tgacattgct cttccatgtg ccactcaaaa cgaaatcaac ggtgaagcag ctaaacgttt
     1741 ggttgctcaa ggcgttatct gtgtatctga aggtgccaac atgccgagcg accttgatgc
     1801 catcaaagtt tacaaagaaa atggtatctt ctacggacct gcaaaagctg ccaacgctgg
     1861 tggtgtagcc gtttcagctc ttgaaatgag ccaaaacagt cttcgcctct catggactcg
     1921 tgaagaagtt gatggccgtc tcaaagacat catgacaaac atcttcaaca cagctaaaac
     1981 gacttcagaa acatacggtc ttgataaaga ctaccttgca ggagctaaca ttgctgcctt
     2041 tgaaaatgta gcaaatgcca tgattgcaca aggtattgtt taagatttat ttactcaatc
     2101 ctcaatcact acgattgggg atttttagct tgaattaaaa aattggaaaa tctaattaaa
     2161 taaaatgaaa tgaaataaaa actgaacaaa ttgattgcgg aattcaaacc aatttctaac
     2221 atacttctag aaattaattt gacttttcta atcgatttgt tcatatctta tttcaattta
     2281 ctatacttac ttaacccttt ttatactcaa tgaaaatcaa agagcaaact aggaagcgag
     2341 ccgcaggctg tacttgagta cggcaaggca aagctgacgt ggtttgaaga gattttcaaa
     2401 gagtattaaa caaaaagaaa aaccgctact cctaagaata gcgatttaat catgttttta
     2461 agctactact gtagttgctc tattatttaa gtgttatgaa taacttcaat atctttaaag
     2521 ctttttgtta gatttataat ttcaactata gccatctcta ctccttagtt tacagcaaaa
     2581 aattatgctt aattcttatt gtttttgtaa acaatcagcg aacccaatac tattccattc
     2641 aacaagccta aagaaatacc atattcaact ggaaaatcta aaaaaattgc aaacactatt
     2701 ccaatcatca cccctagtga ggctattgtt aaaattacat attcattttc tttcttcatt
     2761 ttctttacac ctcatttcct ttttgtatat aagctgtagt actctccacc aagagttatt
     2821 aagtacttat gatttcctga ctcaacaatc ttaccacctt tcattacaaa aataatatcc
     2881 gcatccttaa tcgttgacaa tctatgagct ataattattt gagtacaacc ctgactttgt
     2941 atatactttg ttattctttc ctcattaata gtgtctaatg cactagttgc ttcatctaaa
     3001 attacaatac taggattatt tattaatgca cgtgccagtg ctatctgttg cctttgccca
     3061 cctgaaatat ttgaccccat ctctgagatg atagtattaa atttcatcgg catagccatg
     3121 atttcatcat agatttgaac tgctttacaa acttcctcta tcttttgtga agtaacttcg
     3181 tgctttaaag ttatattatc aagaatactt cggttcaata aaaatgaatc ctgtggaact
     3241 actcctaaat tttgacttaa tattttttta tctatttgat taatatttat accataaaat
     3301 aaaacttttc ctgtatcaat cttatataat cctgatggta tttttgataa tagacttcct
     3361 gcaaaactag aatcctagtt catgattgat aataccaaca atcaaattca tccgtaatcc
     3421 gaagcgttta cgatgatttc gataggttgt tgaaaacatt ttaagcgttt ttactttggc
     3481 aaagatgttc tcaaccttgc ttctctcctt agatagcaca tggttacagg ctttatcttc
     3541 agctgttagc ggcttgagtt tgctggattt acgtggagtt tgtgcttga
//
LOCUS       DAVBEO010000088         3305 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 009
            SAMEA1678075-rid20185393.denovo.088, whole genome shotgun sequence.
ACCESSION   DAVBEO010000088 DAVBEO010000000
VERSION     DAVBEO010000088.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678075
            Sequence Read Archive: ERR226392
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3305)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3305)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980207.1
            Genome Coverage       :: 150x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:50:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 72 of 147
            Pseudo Genes (incomplete)         :: 72 of 147
            Pseudo Genes (internal stop)      :: 42 of 147
            Pseudo Genes (multiple problems)  :: 32 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3305
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678075-rid20185393.denovo.088"
                     /strain="KS 009"
                     /db_xref="taxon:1313"
     gene            complement(384..1859)
                     /locus_tag="VQ543_002075"
     CDS             complement(384..1859)
                     /locus_tag="VQ543_002075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000661022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HET2612726.1"
                     /translation="MKELDQNQAPIYEALVKLRKKRIVPFDVPGHKRGRGNPELVELL
                     GEKCVGIDVNSMKPLDNLGHPISIIRDAEELAADAFGASHAFLMIGGTTSSVQTMILA
                     TCKAGDKIILPRNVHKSAINALVLCGAIPIYIEMSVDPKIGIALGLENDRVAQAIKDH
                     PDAKAILINNPTYYGICSDLKGLTEMAHEAGMMVLVDEAHGAHLHFTGKLPISAMDAG
                     ADMAAVSMHKSGGSLTQSSLLLIGEQMNPEYVRQIINLTQSTSASYLLMASLDISRRN
                     LALRGKESFEEVIELSEYARHEINAIGGYYAYSKELIDGVSVCDFDVTKLSVYTQGIG
                     LTGIEVYDLLRDEYDIQIEFGDIGNILAYISIGDRIQDIERLVGALADIKRLYSRDGK
                     DLIAGEYIQPELVLSPQEAFYSERKSLTLDDSVGQVCGEFVMCYPPGIPILAPGERIT
                     REIVDYIQFAKERGCSLQGTEDPEVNHINVIKRKTNYKKSQ"
     gene            2566..3305
                     /locus_tag="VQ543_002076"
                     /pseudo
     CDS             2566..3305
                     /locus_tag="VQ543_002076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155321.1"
                     /note="internal stop; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
BASE COUNT         1042 a          705 c          614 g          944 t
ORIGIN      
        1 ataagaaaga cgctcatggc atcgctctta aacttctttc tgaccccaat cgtgaacaat
       61 ttcaacacga taatcggcaa gtagaactaa aaatactgac tagacatatt catcgtctca
      121 agaaaaaaca gtctgattgg aaagtacaat acactcgttg tcttgatatc atctttcctg
      181 agttggataa aatcgttgga aagcattcag aatataccta ccaactcttg acacgctacc
      241 ctaatcctca gaaaaggatt gaggcaggat ttgataagct gatagaaatt aagcgattga
      301 ccgcttctaa ttcaagggct ttttgccgtg ctctaaaatc atcgccaaat catcaaattg
      361 aaataagaaa tagtttagat aaactattga cttttcttat agtttgtctt tctcttaata
      421 acgttgatat gattgacctc tggatcttcc gtcccttgga gggagcaacc acgttccttg
      481 gcgaattgga tatagtcgac aatttctcgt gtaatgcgtt caccaggagc caagatagga
      541 atacctggag ggtaacacat aacaaattct ccacagacct gtccaacaga atcatccaaa
      601 gttaaacttt ttctttctga atagaaggct tcttgcggag acagcactaa ctcgggctga
      661 atatattctc ctgctatcaa atcttttcca tctcttgaat agagtctctt aatatcagcc
      721 agagcaccaa ccaagcgctc gatgtcttgg atgcggtcgc cgatggaaat ataggccaag
      781 atattgccga tatcaccaaa ctcgatctga atgtcgtatt cgtctcgcaa gaggtcataa
      841 acctcgatac ctgttaagcc aataccctga gtgtaaactg acaacttagt tacgtcaaaa
      901 tcgcaaaccg aaacaccgtc tattaactct tttgagtagg catagtagcc accgatagca
      961 ttgatttcat gacgagcgta ctcggatagc tcaatgactt cctcaaacga ctctttacca
     1021 cgaagggcca agttgcgacg tgaaatatcc aaactagcca tcaataagta agaggcagat
     1081 gtagactggg tcaggtttat aatctgacga acgtactcgg gattcatctg ctccccgatt
     1141 aaaagaagcg aactttgtgt caaactccca ccagacttat gcatggaaac tgctgccata
     1201 tcagctcctg catccatagc agaaattgga agtttaccag tgaaatgcaa atgcgctcca
     1261 tgggcttcat ctactaaaac catcatgcca gcttcatgag ccatttctgt caaccccttt
     1321 aggtctgaac agatgccgta gtaagtagga ttgttgatta ggatagcctt agcatctgga
     1381 tggtccttta tggcctgtgc tactcggtca ttttcaagac ctaaagcgat accaatctta
     1441 ggatctacac tcatctcgat atagatggga atggcaccac atagaaccaa cgcattgata
     1501 gcagatttat ggacatttcg tggcagaata atcttatctc ctgccttgca ggttgccaga
     1561 atcatagtct gcaccgatga agttgttcca ccaatcatta gaaaggcatg gctagctcca
     1621 aaagcatctg cagccagctc ctctgcatca cgaataatcg aaataggatg gcctaaatta
     1681 tccaagggtt tcatcgaatt gacatcaatg cctacacatt tttctcctaa gagttcgaca
     1741 agttctggat ttccccgtcc acgcttgtga cctggaacat caaagggaac aatccttttc
     1801 ttgcgtaact tcaccaaggc ctcataaatt ggggcttggt tttgatctaa ctctttcaaa
     1861 acatactcct ttcaatattt ttaggacctt atgaaaacta aggaactaaa ggttgactca
     1921 tgaaaaaaga gcaggttttc acctgctctg caatcttctg acgtgtttat tttggtttct
     1981 gttgagtatg tctgttcccg atgtttccta actctctagt agcaaatatt acgtacttta
     2041 ttgatcgttt cacaagatga cgtgtgcttt caccacacta aaaatttatg aattaggaca
     2101 agtgtcctaa catcaactta taaaagtagg cttttaaccc tatcaataat gtggcttttc
     2161 aaccacgctt cggcattcaa ccctgcctgt ccgtaggcat tttttactcg ggtttatatt
     2221 tgctagaaaa catcatctca ttttctaagc tttattacta tatcatgttt ttaagaactt
     2281 gtaaagtatt ttttgataaa aaacaaaaat ataatagatt gaaactagaa tagtacacct
     2341 ctgcttctaa aacattgtta gaaatagatt ttactgtcct gatcgatttg ttctgttctt
     2401 gtttcatttt actatatgtt cgtaaatgaa agttctataa tgaagttagc cacccagccc
     2461 tcctaaaaat tagatggttc aactagctga tagctcttgt aggcataaga aaacacctct
     2521 gtgttatact tgttgttcaa ccacaaacac aagaaaggca cagaaatgca agacaattat
     2581 actacaaaag gtaaacattt gacaatcgat agccgtcgct taatcgaaag atggaaaaaa
     2641 gaaggaaaat caaatagaga aattgcctct ctacttggaa aagctcctca aactatccac
     2701 actaaaatca agcgtaggac agtccgaaaa tgtcttggaa aagggcgctt caaagaggtt
     2761 tattctgccg actatgctca acagtcttat gaaaataatc gcaagcactc ggtcaagaga
     2821 tcaagcgtga ccaaggaact aaaggaaaag attctccact atcataacca aaaatttttg
     2881 cctgaaatga tggttatggc taaaggggtt aacgtgggaa tttcaaccat ttactattgg
     2941 attcatcatg gaaaattggg gtaaagcaag caggatctgc tttaccctag aaaaggaaaa
     3001 gtgcttaaga aacaggccag caccaacttt aaacctgctg gtcaatccat cgaacagcgg
     3061 cttgaagcta tcaattttcg cttggagaat gggcattatg agattgatac ggttctactt
     3121 acgagagcga aaaactactg cttgcttgtc ttgacggatc gaaaaagtag acatcagatc
     3181 atccgattga ttccaaataa aagtgctgag gtggtcaatc aggctctaaa actcatctta
     3241 aaacaacaca agattctttc catcacggca gataatggaa cggaattcaa tcgcttgtct
     3301 gatgt
//
LOCUS       DAVBEO010000089         2796 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 009
            SAMEA1678075-rid20185393.denovo.089, whole genome shotgun sequence.
ACCESSION   DAVBEO010000089 DAVBEO010000000
VERSION     DAVBEO010000089.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678075
            Sequence Read Archive: ERR226392
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2796)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2796)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980207.1
            Genome Coverage       :: 150x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:50:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 72 of 147
            Pseudo Genes (incomplete)         :: 72 of 147
            Pseudo Genes (internal stop)      :: 42 of 147
            Pseudo Genes (multiple problems)  :: 32 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2796
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678075-rid20185393.denovo.089"
                     /strain="KS 009"
                     /db_xref="taxon:1313"
     gene            complement(<1..201)
                     /locus_tag="VQ543_002077"
     CDS             complement(<1..201)
                     /locus_tag="VQ543_002077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
                     /protein_id="HET2612727.1"
                     /translation="MNDEASKQLTDARFKRLVGVQRTTFKEMLAVLKTAYQLKHAKGG
                     RKPKLSLEDLLMATLQYVREYRT"
     gene            240..1157
                     /locus_tag="VQ543_002078"
                     /pseudo
     CDS             240..1157
                     /locus_tag="VQ543_002078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001822901.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="sodium-dependent transporter"
     gene            complement(1197..2141)
                     /gene="manA"
                     /locus_tag="VQ543_002079"
     CDS             complement(1197..2141)
                     /gene="manA"
                     /locus_tag="VQ543_002079"
                     /EC_number="5.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-6-phosphate isomerase, class I"
                     /protein_id="HET2612728.1"
                     /translation="MSEPLFLQSVMQEKIWGGTKLRDEFGYDIPSEKVGEYWAISAHL
                     NGVSKVANGRYEGTDLATLYAEHRELFGNRPEPVFPLLTKILDANDWLSVQVHPDDAY
                     GLEHEGELGKTECWYIIAADEGSEIIYGHNAKSKEELRQQIEDKNWDALLTKVPVKAG
                     DFFYVPSGTMHAIGAGILILETQQSSDTTYRVYDFDRKDDKGNLRELHLEKSIDVLNI
                     GEPANSRPVTIKADDLRSTILVSNDFFAVYKWEITGKVNFEKTADYSLLSVLAGQGQL
                     TVDGKNYPIQKGRHFILPSDVESWTLEGQDLELIVSHP"
     gene            complement(2273..2554)
                     /locus_tag="VQ543_002080"
     CDS             complement(2273..2554)
                     /locus_tag="VQ543_002080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000380698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 1 glycosylhydrolase"
                     /protein_id="HET2612729.1"
                     /translation="MDTPDENGYVADDYRITYLEAHIKAMRDAIYKDGVDLLGYTTWG
                     CIDSVSAGTGEMNKRYGFIYVDRDNVGNGTLKRSKKKSFYWYMSFIAMV"
     gene            2619..2741
                     /locus_tag="VQ543_002081"
                     /pseudo
     CDS             2619..2741
                     /locus_tag="VQ543_002081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
BASE COUNT          750 a          644 c          509 g          893 t
ORIGIN      
        1 agttcgatat tctcgcacat attgaagagt ggccataaga aggtcttcta ggcttaattt
       61 aggttttcgt ccaccttttg cgtgtttaag ttgataagct gtttttaata cagctaacat
      121 ctctttaaaa gtcgtgcgct gaacaccaac aagacgctta aatcgtgcat cagttagttg
      181 tttacttgct tcatcattca tagaactact atgccatatt ttgtttcgca ggaagtctga
      241 tcatttcaaa tccagccatt gctctaggag ctcaagcgac ctttatccta ttgaatatct
      301 tcattgtatc acgtggggtt caaaaaggga ttgaaagagc ttcgaaagtc atgatgcccc
      361 tgctctttat catctttgtc gtcatcatcg aacgctctct cagtttgcca aatgccatgg
      421 aaggggttct ttacttcctc aaaccagatt tttcaaaact gactagcgct ggtctcctct
      481 atgctctgag acaatctttc tttgccctct cactaggggt tacagccatg ttgacctatg
      541 cttcttactt ggacaagaaa accaatctgg tccagtcaag aatctccatc gtagccatga
      601 atatctcggt atccatcatg gcaggtctag ccattttcca agctcggtcc cccttcagac
      661 tgaatattga agggggaccg agcttggtct ttatcgtctt gcctcaactc tttgacaaga
      721 tgccttttgg aaccattttc tatgtcctct tcctctttgc gactgtcact tcttctgtcg
      781 ttatgctgga aatcaatgta gacaatatca ccaatcagga caacagcaag cgtgctaaat
      841 ggagtgttat tttaggaatt ttgacctttg tctttggcat tccttcagcc ctatcttacg
      901 gtgtcatggc ggatgttcac atttttggta aagccttctt tgacgctatg gacttcttgg
      961 tttccaatct cctcatgcca tttggagctc tcttcctttc actttttaca ggctatatct
     1021 ttaaaaaggc tcttgcaatg gaggaactcc atctcgatga aagagcatgg aaacaaggac
     1081 tgttccaagt ctggctcttc cttcttcgtt tcgtcattcc aatcatcatc gtggtcttca
     1141 tcgcccaatt tatgtaatca aaaggacttg agtaatgaac tcaggtcctt tcttttttat
     1201 ggatgactaa caattaattc taaatcttgc ccttctagag tccaagattc aacatcactt
     1261 ggtaggataa agtgtctccc tttttggatt ggatagtttt tcccgtcaac agttagttga
     1321 ccttgaccag ccaagacact caacaagctg tagtcagctg tcttttcaaa gttaactttt
     1381 ccagtaattt cccatttgta aactgcgaag aaatcattgg atacaaggat agtggaacgt
     1441 agatcatctg ctttgattgt cactggacgg ctatttgcgg gttcaccaat gttcaagaca
     1501 tcgatagatt tttcaaggtg aagttcacgt aaattgccct tgtcatcctt acggtcaaag
     1561 tcatagacac ggtaagtggt atcgctagac tgctgggttt caagaatcaa gatacccgcc
     1621 ccgatagcgt gcatggtacc gcttggtaca tagaagaaat ctcctgcttt aactggcact
     1681 tttgtcaaca gcgcatccca gttcttatcc tcgatttgct ggcggagttc ttcttttgac
     1741 ttggcattgt gaccgtagat aatctctgaa ccttcatctg ctgcaatgat gtaccaacat
     1801 tctgtttttc caagttcgcc ttcatgctcg agtccataag catcgtctgg gtgaacttgg
     1861 acactgagcc agtcgttggc atcgaggatc ttggtcaaaa gtggaaatac aggttctgga
     1921 cgattgccaa ataattcacg gtgttccgca tacaaagtag caagatctgt tccctcgtaa
     1981 cgaccattgg caactttaga aacaccattt agatgagctg agatagccca gtactctccg
     2041 actttttcac ttgggatgtc gtagccaaac tcatcacgta gcttggtacc accccagatt
     2101 ttttcttgca taactgattg taaaaataat ggttctgaca tcttaatctc ctgtctgatt
     2161 tttctcccct cattatagca aaaaaagagt tccatttgaa ctctttttta catcttataa
     2221 agcagggaga agattttata aaaatagtaa acaaatgtgc tctactcgat gcttacacca
     2281 ttgctataaa tgacatgtac caatagaagg acttcttctt gctacgtttg agagtcccat
     2341 ttcctacatt atctcgatct acatagataa agccatagcg cttattcatt tcccctgtgc
     2401 cagctgaaac cgaatcgata cagccccatg tcgtataacc aagcaagtca accccgtctt
     2461 tgtaaatggc atctcgcatg gccttgatgt gggcctctaa gtaagtaatc cgatagtcat
     2521 ctgctacata accattctca tccggtgtat ccatagcacc gagtccattt tctacgataa
     2581 tactatacta aaatcaaaaa gcattatata atagtgatat gaaatcaact aaagaagaaa
     2641 tccaaaccat caaaacactt tttaaagact ctcgtacagc taaatatcat aaatgccttc
     2701 aaatcattct atttcgtctg atgggcaaat cttataaaga ctccgactaa tattggtttt
     2761 gcatttattc ctccatacac accagagatg aaccca
//
LOCUS       DAVBEO010000090         2624 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 009
            SAMEA1678075-rid20185393.denovo.090, whole genome shotgun sequence.
ACCESSION   DAVBEO010000090 DAVBEO010000000
VERSION     DAVBEO010000090.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678075
            Sequence Read Archive: ERR226392
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2624)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2624)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980207.1
            Genome Coverage       :: 150x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:50:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 72 of 147
            Pseudo Genes (incomplete)         :: 72 of 147
            Pseudo Genes (internal stop)      :: 42 of 147
            Pseudo Genes (multiple problems)  :: 32 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2624
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678075-rid20185393.denovo.090"
                     /strain="KS 009"
                     /db_xref="taxon:1313"
     gene            206..520
                     /locus_tag="VQ543_002082"
     CDS             206..520
                     /locus_tag="VQ543_002082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2612730.1"
                     /translation="MWVLGFILFLIFFYSNDSKKIKKLEKKIKRLERKEKGNAEMSRL
                     LQEMIGKEPIITGVYIGPDNWEVVDVDEEWVKLRRVDNTGKEKFKLQRIEDIQTVEFD
                     GE"
     gene            530..736
                     /locus_tag="VQ543_002083"
     CDS             530..736
                     /locus_tag="VQ543_002083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001176227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET2612731.1"
                     /translation="MQLKNRLKELRARDGLNQTDLAKLAGVSRQTISLLERDEYTPSI
                     IIALKISQIFNETVESVFRLEEDE"
     gene            736..933
                     /locus_tag="VQ543_002084"
     CDS             736..933
                     /locus_tag="VQ543_002084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001046145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2612732.1"
                     /translation="MNKYKVIYYVVVIALLVSVFLLIGMDLSWFNPYQSDQFVWVYFA
                     LIPVIEWIEKKSKNLASEKGE"
     gene            989..1669
                     /locus_tag="VQ543_002085"
     CDS             989..1669
                     /locus_tag="VQ543_002085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001833114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3169 family protein"
                     /protein_id="HET2612733.1"
                     /translation="MGMFVGMFKARVESHEIILDVKALMPWISAICLLIGFISMFLTF
                     NFLKKSRKFHSLYQEEMDDDLNETYYVQMYRNLEFGTIAFNITGVVIPLAIFISLSEV
                     IILHTNPQTFFLSFLLFVVFLVAQKSLFKTIAIVRQFDLEFFATPKDVLNYINSYDEG
                     ERQANLEQSFRILFQLHQYVLPALYIFLIILSFLTGEIQLLAFLLVGAIHVYINVMQL
                     PMVKRYFK"
     gene            1681..2322
                     /locus_tag="VQ543_002086"
     CDS             1681..2322
                     /locus_tag="VQ543_002086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET2612734.1"
                     /translation="MKLLKNLGWFLLALLSFFFIYGFIQGLATASLALGASPYAVTLL
                     YVVLAGVYVYGIYKWYQKAPVYIEKSGFNRFIWLPALVWFLSLVVQFFLPDDPSVNQQ
                     IATDLTLSQPLFSFFAVVIFAPLTEEIVFRGMLARYLFPKQDNSKRTLIFLLVSSLLF
                     ALIHFPGDVQQFFVYFSLGFSLGLAYISRKGLVYSISLHALNNLVGFLMILML"
     gene            2340..2570
                     /locus_tag="VQ543_002087"
     CDS             2340..2570
                     /locus_tag="VQ543_002087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000832182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2612735.1"
                     /translation="MKRVILLAVIQAVVLFFIIGALAYAFKGDFFYNYLAVVFAPIAG
                     VLRFGTAYITEIVLPRKAAEIAEKRKAGKNSK"
BASE COUNT          766 a          431 c          541 g          886 t
ORIGIN      
        1 atacctacgg caaggtgaag ctgacgtggt ttgaagagat tttagaagag tattaatgat
       61 agataaagtg gtcaggaacc tactcctgac ctttttcttt tgcaaaatga caaaaatcat
      121 aatttttttg acaactatac ttgtcaaaaa gaaaaagatg tgttacaatg taagcaagtt
      181 aagagaaaag aagaaaggag ctatgatgtg ggtactaggg tttatactat ttctgatttt
      241 cttttattct aatgattcta aaaaaatcaa gaaactagag aagaaaatca aaagacttga
      301 gcgaaaagag aaaggaaatg cagaaatgtc gagattatta caagaaatga ttggaaagga
      361 accaattata acgggagtgt atattgggcc agataactgg gaagttgtgg atgttgatga
      421 ggaatgggta aagctacgac gtgtagataa tacgggaaaa gaaaaattca agttgcaacg
      481 tattgaggat atccaaaccg ttgaatttga cggagagtag gtgtgtaaca tgcaactaaa
      541 aaatcgtcta aaagagcttc gagctcgcga tggtctcaat caaaccgacc tagccaaact
      601 ggcaggggtt tccagacaga ccattagcct actagaacgg gatgagtaca ccccatccat
      661 tatcattgcc ctgaaaatat ctcaaatttt caacgaaaca gtcgaatcgg tatttcgttt
      721 ggaggaggac gagtgatgaa caagtataaa gtgatttatt atgtagtggt catagcttta
      781 ttagtcagcg tatttctact gattgggatg gacctaagct ggtttaatcc ctatcaaagc
      841 gaccaatttg tttgggtcta ctttgctctc atcccagtaa ttgaatggat tgaaaagaaa
      901 tccaaaaatc tagcaagtga aaaaggagaa tgaatatgaa aaagaaacgt agattgttat
      961 ttttgatgtc tattgtcttg gggggttctt gggcatgttt gtagggatgt ttaaggcacg
     1021 tgtcgaatcc cacgaaatta ttttagatgt aaaagccttg atgccatgga tatcagctat
     1081 ttgtttactg ataggtttca ttagtatgtt tttgactttc aatttcttaa agaaaagcag
     1141 aaaatttcat tccttgtatc aagaggaaat ggatgacgat ctgaatgaaa cctattatgt
     1201 gcaaatgtat cggaatcttg agtttggaac cattgctttt aatattacag gtgtagtgat
     1261 tccattggct atttttattt cattaagtga ggtgattata ttgcatacaa accctcaaac
     1321 atttttcctt tctttcttac tctttgtggt attcttagtc gctcaaaaat ctctttttaa
     1381 aaccattgcg attgttcgtc agtttgattt ggaatttttc gctacaccaa aggatgtctt
     1441 gaactatata aattcttatg atgaagggga gcgtcaggct aatttggaac agagttttcg
     1501 aattttattc caattacacc aatatgtctt accagcctta tatatttttc ttattatcct
     1561 ttctttcttg acaggagaga ttcagttact agctttcttg cttgtaggag ccatccatgt
     1621 ttatatcaat gtgatgcagt tacctatggt aaaacgttat ttcaaataaa ggagttatct
     1681 atgaaattac ttaaaaacct tggctggttt cttctagccc ttctatcctt tttctttatc
     1741 tatggcttta ttcaggggct cgcgactgcg tcgcttgctt taggcgcttc accctatgct
     1801 gttactctac tctatgtggt cttggctgga gtatatgtgt acggcattta caaatggtat
     1861 cagaaagctc ctgtttatat tgagaagagc ggctttaacc gatttatttg gcttcctgcc
     1921 ttggtttggt tcttatctct ggtcgttcaa ttcttcttgc cagatgatcc ttcagtaaat
     1981 cagcaaatag cgacagactt gaccttgtct caaccacttt tctcattctt tgctgtggtt
     2041 atttttgctc ctttgacgga agagattgtt tttagaggga tgttagcacg ctatctcttt
     2101 cctaagcagg acaatagtaa acgaaccctg atttttcttc tggtatctag tcttctattt
     2161 gccttgattc attttccagg tgatgtgcaa caattttttg tctattttag ccttggtttt
     2221 agtttgggtt tggcttacat tagcagaaaa ggtctggtct acagtatttc tcttcacgct
     2281 ttgaataatt tagtcggctt tttgatgatt ctcatgctat aatagagtca ggaggtcaca
     2341 tgaaacgagt aattttatta gcagtgattc aggcagtcgt tctatttttc atcattggag
     2401 cgctagctta tgccttcaaa ggcgatttct tctataacta tctagcagtt gtctttgctc
     2461 ctattgcagg tgtactgcgt tttgggacgg cttacataac ggaaattgtc ttgcctcgaa
     2521 aggcagccga aatcgctgaa aagcgtaaag caggcaaaaa ttcaaaataa aagagtccgg
     2581 tgaagttcat cggatttttg tattatactc aatgaaaatc aaag
//
LOCUS       DAVBEO010000091         2352 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 009
            SAMEA1678075-rid20185393.denovo.091, whole genome shotgun sequence.
ACCESSION   DAVBEO010000091 DAVBEO010000000
VERSION     DAVBEO010000091.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678075
            Sequence Read Archive: ERR226392
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2352)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2352)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980207.1
            Genome Coverage       :: 150x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:50:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 72 of 147
            Pseudo Genes (incomplete)         :: 72 of 147
            Pseudo Genes (internal stop)      :: 42 of 147
            Pseudo Genes (multiple problems)  :: 32 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2352
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678075-rid20185393.denovo.091"
                     /strain="KS 009"
                     /db_xref="taxon:1313"
     gene            complement(26..428)
                     /locus_tag="VQ543_002088"
                     /pseudo
     CDS             complement(26..428)
                     /locus_tag="VQ543_002088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            complement(373..555)
                     /locus_tag="VQ543_002089"
     CDS             complement(373..555)
                     /locus_tag="VQ543_002089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HET2612736.1"
                     /translation="MDLKFEGVDLEYKKAKNNLPESFWETYSAFANTNGGKIILGIDE
                     KNIDTYQRVNRLPAKL"
     gene            912..>2352
                     /gene="pcpA"
                     /locus_tag="VQ543_002090"
     CDS             912..>2352
                     /gene="pcpA"
                     /locus_tag="VQ543_002090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000753868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein PcpA"
                     /protein_id="HET2612737.1"
                     /translation="MKKTTILSLTTAAVILAAYVPNEPILADTPSSEVIKETKVGSII
                     QQNNIKYKVLTVEGNIGTVQVGNGVTPVEFEAGQDGKPFTIPTKITVGDKVFTVTEVA
                     SQAFSYYPDETGRIVYYPSSITIPSSIKKIQKKGFHGSKAKTIIFDKGSQLEKIEDGA
                     FDFSELEEIELPASLEYIGTSAFSFSQKLKKLTFSSSSKLELISHEAFANLSNLEKLT
                     LPKSVKTLGSNLFRLTTSLKHVDVEEGNESFASVDGVLFSKDKTQLIYYPSQKNDESY
                     KTPKETKELASYSFNKNSYLKKLELNEGLEKIGTFAFADAIKLEEISLPNSLETIERL
                     AFYGNLELKELILPDNVKNFGKHVMNGLPKLKSLTIGNNINSLPSFFLSGVLDSLKEI
                     HIKNKSTEFSVKKDTFAIPETVKFYVTSEHIKDVLKSNLSTSNDIIVEKVDNIKQETD
                     VAKPKKNSNQGVVGWVKDKGLWYYLNESGS"
BASE COUNT          822 a          354 c          385 g          791 t
ORIGIN      
        1 tgagccttca tagcgtggca tttcttttta cttccgtcac atcaatcatt accgtgtcct
       61 cagaactgag aggagttctt gaaatcgtaa caccaccttt gaacaagagt tacttcaacc
      121 cattagctcc gacggattaa gttgctttcg tgaataccaa aatcagccgc aatttcttca
      181 taagtgcggt attctcgcac atattgaaga gtggccataa gaaggtcttc taggcttaat
      241 ttaggttttc gtccaccttt tgtgtgttta agttgataag ctgtttttaa cacagctaac
      301 atctcttcaa aagtggtgcg ctgaacacca acaagacgct taaatcgtgc atcggttagt
      361 tgtttacttg cttcataatt tcgcagggag tctattgact ctttggtagg tgtcaatgtt
      421 tttttcatct atcccgagaa ttattttccc gccatttgta tttgcaaatg ctgagtaggt
      481 ttcccagaaa gactctggaa gattgttttt agcttttttg tattctaaat caaccccttc
      541 aaattttaag tccatatttt tcctttacat ctgttttttg tggttctggt atttgttcaa
      601 gttgagtgat aatatagcga attgaatttc gagagttttt actcagttaa tttctttttt
      661 aacccacttt aatttctttt ttaacccact ttaatttctt ttttaacacg ggttaaaaaa
      721 gaaattaaag tgggttaatt tttcttgact taaaatttaa aaatgatata ctgtgtttat
      781 ggagagatga caatttataa aatgtactac tctattctac tagataatga ttgaataaaa
      841 ctttttataa caacggctag caaagttata attttatatc tattagaaaa taaatatgta
      901 aggaaattta aatgaaaaaa actacaatat tatcattaac tacagctgcg gttattttag
      961 cagcatatgt ccctaatgaa ccaatcctag cagatactcc tagttcggaa gtaatcaaag
     1021 agactaaagt tggaagtatt attcaacaaa ataatatcaa atataaggtt ctaactgtag
     1081 aaggtaacat aggaactgtt caagtgggta atggagttac tcctgtagag tttgaagctg
     1141 gtcaagatgg aaaaccattc acgattccta caaaaatcac agtaggtgat aaagtattta
     1201 ccgttactga agtagctagt caagctttta gttattatcc agatgaaaca ggtagaattg
     1261 tctactatcc tagctctatt actatcccat caagcataaa aaaaatacaa aaaaaaggct
     1321 tccatggaag taaagctaaa actattattt ttgacaaagg cagtcagctg gagaaaattg
     1381 aagatggagc ttttgatttt tctgaattag aagagattga attgcctgca tctctagaat
     1441 atattggaac aagtgcattt tcttttagtc aaaaattgaa aaagctaacc ttttcctcaa
     1501 gttcaaaatt agaattaata tcacatgagg cttttgctaa tttatcaaat ttagagaaac
     1561 taacattacc aaaatcggtt aaaacattag gaagtaatct atttagactc actactagct
     1621 taaaacatgt tgatgttgaa gaaggaaatg aatcgtttgc ctcagttgat ggtgttttgt
     1681 tttcaaaaga taaaacccaa ttaatttatt atccaagtca aaaaaatgac gaaagttata
     1741 aaacgcctaa ggagacaaaa gaacttgcat catattcgtt taataaaaat tcttacttga
     1801 aaaaactcga attgaatgaa ggtttagaaa aaatcggtac ttttgcattt gcagatgcga
     1861 ttaaacttga agaaattagc ttaccaaata gtttagaaac tattgaacgt ttagcctttt
     1921 acggtaattt agaattaaaa gaacttatat taccagataa tgttaaaaat tttggtaaac
     1981 acgttatgaa cggtttacca aaattaaaaa gtttaacaat tggtaataat atcaactcat
     2041 tgccgtcctt cttcctaagt ggcgtcttag attcattaaa ggaaattcat attaagaata
     2101 aaagtacaga gttttctgtg aaaaaagata catttgcaat tcctgaaact gttaagttct
     2161 atgtaacatc agaacatata aaagatgttc ttaaatcaaa tttatctact agtaatgata
     2221 tcattgttga aaaagtagat aatataaaac aagaaactga tgtagctaaa cctaaaaaga
     2281 attctaatca gggagtagtt ggttgggtta aagacaaagg tttatggtat tacttaaatg
     2341 aatcaggttc aa
//
LOCUS       DAVBEO010000092         1671 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 009
            SAMEA1678075-rid20185393.denovo.092, whole genome shotgun sequence.
ACCESSION   DAVBEO010000092 DAVBEO010000000
VERSION     DAVBEO010000092.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678075
            Sequence Read Archive: ERR226392
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1671)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1671)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980207.1
            Genome Coverage       :: 150x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:50:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 72 of 147
            Pseudo Genes (incomplete)         :: 72 of 147
            Pseudo Genes (internal stop)      :: 42 of 147
            Pseudo Genes (multiple problems)  :: 32 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1671
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678075-rid20185393.denovo.092"
                     /strain="KS 009"
                     /db_xref="taxon:1313"
     gene            100..1575
                     /locus_tag="VQ543_002091"
     CDS             100..1575
                     /locus_tag="VQ543_002091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000338710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HET2612738.1"
                     /translation="MDAIFDLIGKVFNPILEMGGPVIMLIILTVLALLFGVKFSKALE
                     GGIKLAIALTGIGAIIGMLNGAFSASLAKFVENTGIQLSITDVGWAPLATITWGSAWT
                     LYFLLIMLIVNIVMLAMKKTDTLDVDIFDIWHLSITGLLIKWYADNNGVSQGVSLFIA
                     TAAIVLVGVLKIINSDLMKPTFDDLLNAPSSSPMTSTHMNYMMNPVIMVLDKIFEKFF
                     PGLDKYDFDAAKLNKKIGFWGSKFFIGFILGIVIGIMGTPHPIAGVADADKWRLVIKG
                     WLSLGLTAGVSLELFSLIGSWFIAAVEPLSQGITNVATKRLQGRKFNIGLDWPFIAGR
                     AEIWACANVLAPIMLIEAVLLSKVGNGILPLAGIIAMGVTPALLVVTRGKLLRMIIFG
                     TLLLPLFLLSGTLIAPFATELAKGVGAFPEGVSQTQLITHSTLEGPIEKLLGWTIGNT
                     TTGDIKAILGAVVFLVFYIGIFAWYRKQMIKRNEEYAAKAK"
BASE COUNT          474 a          335 c          334 g          528 t
ORIGIN      
        1 tccagtattt gacaatattg aagcagctat taaagaacac ggattaagct aattctaatt
       61 tgttaacatt catataacat aaaaaaggga ggaactgtta tggatgcaat ctttgaccta
      121 atcggaaagg ttttcaatcc cattttagaa atgggtggac ctgtcatcat gttaatcatt
      181 ttgacagtat tggctttact ttttggagtg aaattctcca aagcgcttga aggtggtatc
      241 aaacttgcca tcgctcttac aggtatcggt gctatcatcg gtatgctaaa tggtgctttc
      301 tcagcatcac ttgcaaaatt cgttgaaaac actggtatcc aattgagtat taccgacgtt
      361 ggttgggcac cactcgcaac aatcacttgg ggttctgctt ggacactata cttcttgctc
      421 atcatgttga ttgtcaacat agtgatgcta gctatgaaga aaacagatac acttgacgtt
      481 gatatctttg atatctggca cttgtctatc acaggtctct tgattaaatg gtatgctgat
      541 aacaatggtg tgagtcaagg ggtttcactc tttattgcta cagcagctat cgtccttgtc
      601 ggtgtgttga aaattatcaa ctctgacttg atgaaaccta catttgatga ccttcttaac
      661 gccccaagtt catcaccaat gacatcaact cacatgaact acatgatgaa cccagttatc
      721 atggttttgg ataagatttt tgaaaaattc ttcccaggcc ttgataaata tgactttgat
      781 gctgctaaat tgaacaagaa aatcggtttc tggggatcta aattcttcat cggtttcatc
      841 cttggtatcg ttatcggtat tatgggaact ccacatccaa ttgcaggtgt tgcagatgca
      901 gataaatggc gtcttgttat caaaggatgg ttgtctcttg gtttgactgc cggtgtatct
      961 ttggaactct tctcacttat cggttcatgg ttcatcgcag ccgtagaacc actatcacaa
     1021 ggtattacaa acgttgctac taaacgtctt caaggacgta aattcaatat cggtcttgac
     1081 tggccattca tcgctggtcg tgctgaaatc tgggcttgtg ccaacgtact tgcaccaatc
     1141 atgttgattg aagcagtgct tctttcaaaa gttggaaatg gtatcttgcc acttgcaggt
     1201 atcatcgcta tgggtgttac tccagctctc ttggttgtaa ctcgtggtaa attgctccgt
     1261 atgattatct tcggaacact cttgttgcca ctcttccttc tttcaggtac acttattgca
     1321 ccatttgcaa cagaacttgc taaaggtgta ggtgccttcc cagaaggtgt gagccaaact
     1381 caattgatta ctcactctac tcttgaagga ccaatcgaaa aacttcttgg ttggacaatt
     1441 ggtaacacta caactggtga tatcaaagca atccttggtg cagtagtctt ccttgtattc
     1501 tatatcggta tctttgcttg gtacagaaaa caaatgatca aacgtaacga agagtacgca
     1561 gcaaaagcaa aataatgcgc tcctataaaa tataaactca atgaaaatca aagagcaaac
     1621 taggaaacta gccacaggtt gctcaaaaca cagttttgag gttgtagata a
//
LOCUS       DAVBEO010000093         1651 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 009
            SAMEA1678075-rid20185393.denovo.093, whole genome shotgun sequence.
ACCESSION   DAVBEO010000093 DAVBEO010000000
VERSION     DAVBEO010000093.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678075
            Sequence Read Archive: ERR226392
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1651)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1651)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980207.1
            Genome Coverage       :: 150x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:50:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 72 of 147
            Pseudo Genes (incomplete)         :: 72 of 147
            Pseudo Genes (internal stop)      :: 42 of 147
            Pseudo Genes (multiple problems)  :: 32 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1651
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678075-rid20185393.denovo.093"
                     /strain="KS 009"
                     /db_xref="taxon:1313"
     gene            108..407
                     /locus_tag="VQ543_002092"
     CDS             108..407
                     /locus_tag="VQ543_002092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000378912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic biosynthesis protein"
                     /protein_id="HET2612739.1"
                     /translation="MDSYAINFWESKGVGIDKKILEFIQKNITVIKNKNFLNKDFDIY
                     VKKIHNLFFVISTLVSKEQYMGIVSSQIHMFANRMGISPTIEVTMLDFFLREDSD"
     gene            409..1179
                     /locus_tag="VQ543_002093"
     CDS             409..1179
                     /locus_tag="VQ543_002093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000417117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SagB/ThcOx family dehydrogenase"
                     /protein_id="HET2612740.1"
                     /translation="MEKYFFDISIFEKIKKVLSYQSKYWEISKPRDKYSFKSQNRISG
                     SNSIKFKDFELDYELESLGKILLKRRSFLLNEFDKNASFDKLIYLLKTVFSPTNCKFV
                     FGEEVPLFSYPTSGALNSITPFVYIDNMDEVKNGIYEVKYDGLEFKKSMNIIDLETFT
                     PITSKNSDVQNNSFKKVNMIIMLCSNYENIFNKYGLLAYRLLHLEAGHIAQNIQLVST
                     ALGIKSLPMGGWFDDKIETFINEISDKKNIYLYAIAVG"
     gene            1199..1363
                     /locus_tag="VQ543_002094"
     CDS             1199..1363
                     /locus_tag="VQ543_002094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2612741.1"
                     /translation="MNAEDKFRELENENKLLKLHNKELENEIQNGWKFWIWVTVPILG
                     LIYAIIQKIF"
BASE COUNT          608 a          181 c          269 g          593 t
ORIGIN      
        1 ataactatta ttacgaaaaa aaattcttgt gtaaaattct attgactttc tatattattt
       61 ttgtatttca taacgaatgt aatttaacaa gtgaagaaat tttaaagatg gattcctatg
      121 ctattaattt ctgggagagt aaaggggtcg gtattgacaa aaaaatcttg gaatttattc
      181 aaaaaaatat tacagttatt aaaaataaaa attttttgaa taaagatttt gatatttatg
      241 ttaaaaagat tcataattta ttctttgtca tttctacttt agtttcaaaa gagcaataca
      301 tggggatagt ttcttcccaa atacatatgt tcgcaaatag gatgggaatt tctcccacca
      361 ttgaagttac catgctagat ttttttctga gggaggattc tgattaatat ggaaaaatat
      421 ttttttgata tttctatttt tgaaaaaata aaaaaagtat tatcatacca atctaaatat
      481 tgggaaatat cgaagcctag ggataagtac agtttcaaaa gtcaaaatag aatatctggc
      541 tctaatagca ttaaatttaa agattttgag ttagattatg aactggagtc acttggtaaa
      601 atacttttaa aaaggagatc gtttttacta aatgaatttg ataagaatgc gagttttgac
      661 aaactgattt acttgttgaa aactgtattc tctcctacaa attgcaagtt tgtatttgga
      721 gaagaggttc ctttatttag ctatcctaca tcaggtgcgt taaattcaat tactcctttt
      781 gtttatattg ataatatgga tgaagtaaag aatggtatat atgaagtaaa gtatgacgga
      841 cttgaattta aaaaaagtat gaatattata gacttagaaa catttacccc aataacaagt
      901 aaaaacagtg acgtacaaaa taattcattt aaaaaggtaa atatgataat tatgttatgt
      961 tcgaattatg aaaatatttt caataaatat ggattattag cttatcgact tttgcattta
     1021 gaggctggtc atattgcaca aaatatccag cttgtttcta ctgcgctagg aataaaaagt
     1081 ttaccgatgg gaggttggtt tgatgataaa atagaaactt ttattaatga aattagtgat
     1141 aaaaaaaata tttatctcta tgcaattgca gttggataaa tttaaggagg aagtgtagat
     1201 gaacgcagag gataaatttc gcgaactaga aaatgaaaat aaacttctaa aacttcataa
     1261 caaggagctt gagaatgaaa ttcaaaatgg atggaaattt tggatatggg taactgtccc
     1321 tattttaggt ttgatatatg ctattattca aaaaattttt taattatgct agtttgtcag
     1381 gttgagtagt ttttgttcaa aatttaataa acttttttca atgaagatta tctaaagatt
     1441 gcttctcaga tgagaatggc ttctctatct tatataaatt atcttcatag agtgtcctgt
     1501 tattcatgtt atcacagaat agatagtttt tttggctcta taatatttgt agtgggtaaa
     1561 tcccctatag atattatgga gcctattttt gtgtagaaaa aaagtcccat atcatctata
     1621 atgaaaagca accaaactat cattagaaag a
//
LOCUS       DAVBEO010000094         1626 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 009
            SAMEA1678075-rid20185393.denovo.094, whole genome shotgun sequence.
ACCESSION   DAVBEO010000094 DAVBEO010000000
VERSION     DAVBEO010000094.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678075
            Sequence Read Archive: ERR226392
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1626)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1626)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980207.1
            Genome Coverage       :: 150x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:50:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 72 of 147
            Pseudo Genes (incomplete)         :: 72 of 147
            Pseudo Genes (internal stop)      :: 42 of 147
            Pseudo Genes (multiple problems)  :: 32 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1626
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678075-rid20185393.denovo.094"
                     /strain="KS 009"
                     /db_xref="taxon:1313"
     gene            complement(704..1626)
                     /locus_tag="VQ543_002095"
                     /pseudo
     CDS             complement(704..1626)
                     /locus_tag="VQ543_002095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="frameshifted; internal stop; incomplete; missing
                     N-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT          468 a          324 c          333 g          501 t
ORIGIN      
        1 tacgtgacag agtccagttc tatcagaccg ttcgttttac agacacaagt gaagtaggat
       61 tacttcgatt agttgtttac cccttcgctc cacttccatt acagaagttt cctcactact
      121 atgggctcgg ctgacttctc atgattcgtt gttactacgc tttcggcgct catgagacct
      181 cacgggataa gccgtacatc tttcctcgtt tatacaagat atgaggacgt taaaaggtta
      241 caatgaaaat aggaaatctg acgcagagtc tttagactct aggaagattt atctttttca
      301 catagacctt agtccgaatt caattactct cgtgatttac gcatataggt tacgactacc
      361 tttttggact ttagagtttt aagccccctt atccgctgta tacgccttac tatcacgttc
      421 ctgttcgtag agcctcgatt tcgctatccc ttcctctgac gattcttatt tcctgcgtca
      481 gacttaaaac ggtctatccc cagaccgttt taatccgcta cctcacgata gtcaggcttg
      541 ggaatcgcta ttgggttcac cggtagcagg tgcccacgga ggacttacac ctcagatgca
      601 cgacatgccc gtcgtactta aaatcagcct aaatgattca ggctgatttt tctattgatt
      661 caaaaaaacg gctctttgtc aactgtagtg ggttgaagaa aagctaagat cgagaaagga
      721 caaatttcgt cctttctttt ttgatattca gagcgataaa aatccgtttt ttgaagtttt
      781 caaagttccg aaaaccaaag gcattgtgct tgataagttt gatgagatta ttggtcgctt
      841 ccaatttggc gtttgaatag ggtagttgaa gggcgttgat aatcttttct ttatctttga
      901 ggaaggtttt aaagacagtc tgaaaaatag gatgaacctg cttcagattg tcctcaataa
      961 gtccgaaaaa tttctctggt tccttattct ggaagtgaaa aagcaagagc tgatagagct
     1021 gatagtggtg tttcaagtct tccgaatagc tcaaaagctt gtctaaaatc tctttattgg
     1081 ttaaatgcat acgaaaagta ggacgataaa aacgcttatc actcagttta cggctatcct
     1141 gttgtatgag cttccagtag cgcttgatag ccttgtattc atgggatttt cgatgaaact
     1201 gattcatgat ttaaacacgc acacgactca tagcacggct aagatgttgc acaatgtgaa
     1261 agcgatcaag aacgatttta gcattcggga gtgaaacagt ctgggagact gtttcagcct
     1321 gagcctagaa atttgaaagc gaagctgtct agctaagtca tagtaagggc taaacatatc
     1381 catagtaata attttgacgc gacatcggac aactctatcg tagcgaagaa agtgatttcg
     1441 aatgatagct tgtgttcttc cctcaagaac agtgatgata ttgagattgt taaaatcttg
     1501 cgcaatgaag ctcatctttc cctttgtaaa agcatactca tcccaagaca taatctcagg
     1561 aagacaagaa aaatcatgtt taaagtgaaa atcattgagc ttacgaatag cagttgaagt
     1621 tgagat
//
LOCUS       DAVBEO010000095         1586 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 009
            SAMEA1678075-rid20185393.denovo.095, whole genome shotgun sequence.
ACCESSION   DAVBEO010000095 DAVBEO010000000
VERSION     DAVBEO010000095.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678075
            Sequence Read Archive: ERR226392
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1586)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1586)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980207.1
            Genome Coverage       :: 150x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:50:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 72 of 147
            Pseudo Genes (incomplete)         :: 72 of 147
            Pseudo Genes (internal stop)      :: 42 of 147
            Pseudo Genes (multiple problems)  :: 32 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1586
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678075-rid20185393.denovo.095"
                     /strain="KS 009"
                     /db_xref="taxon:1313"
     gene            84..491
                     /locus_tag="VQ543_002096"
     CDS             84..491
                     /locus_tag="VQ543_002096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HET2612742.1"
                     /translation="MARYGVYAVIPNPEQKQIVLVQEPNGAWFLPCGEIEAGENHQEA
                     LKRELIEELGFTAEIGTYYGQADEYFYSRHRDTYYYNPAYLYEATSFKEVQKPLENFN
                     HIAWFPIDEAIQNLKRGSHKWAIESWKKQHKIG"
     gene            656..955
                     /locus_tag="VQ543_002097"
     CDS             656..955
                     /locus_tag="VQ543_002097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000767202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HET2612743.1"
                     /translation="MKLINTTNSHSQLVKSQLESTDATLVEVYSAGNTDVIFTQAPLH
                     YEILISNKHRAIREPEIETIQEFFLKRKIDKTSVNEANIKTLYSEKLIGISIPIK"
     gene            1216..1539
                     /gene="tnpB"
                     /locus_tag="VQ543_002098"
     CDS             1216..1539
                     /gene="tnpB"
                     /locus_tag="VQ543_002098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HET2612744.1"
                     /translation="MMIVLSDLGQVHLVCGKTDMRQGIDSLAYVVKTHFELDPFSGQV
                     FLFCGGRKDRFKALYWDGQGFWLLYKRFENGRLTWPSTEKDVKALTSEQVDWLMKGFS
                     ITPQI"
BASE COUNT          544 a          314 c          282 g          446 t
ORIGIN      
        1 actataataa taacgatact agataatgag gaaaatgcaa tggcaaaccc aactttcgga
       61 gaaaaaaagc gaatacagac tatattgctc gctatggcgt atatgcagtt atccctaatc
      121 ctgaacaaaa acaaattgtt cttgttcaag aaccaaatgg tgcttggttc ctaccatgtg
      181 gagaaattga agcaggtgaa aatcatcagg aagccctaaa gcgtgagttg attgaagagc
      241 ttggtttcac agcagaaatt ggtacctatt acggacaagc tgacgaatat ttctattctc
      301 gtcatcgtga tacctactac tacaatcctg cctacctcta tgaagcaact tctttcaaag
      361 aagtacaaaa gccactagaa aactttaatc atattgcctg gttccctatt gacgaggcta
      421 tccaaaacct taaacgtggt agccataaat gggccattga atcttggaaa aaacagcata
      481 agattggcta atactcttcg aaaataaaat tcaaaccacg tcagcgtcgc cttaccgtac
      541 tcaagtatag cctgcggcta gcttcctagt ttgctctttg attttcattg agtataaatc
      601 aagcgacttt attcaaaaag tgctataata gaattagaaa atcggaggaa atattatgaa
      661 gcttatcaat acgacaaact cacactcgca acttgtaaaa agtcaactag aaagtaccga
      721 tgcaaccctt gttgaggttt attctgcagg gaatacagat gttattttta cccaagctcc
      781 gcttcactat gaaatcctca tctcaaacaa acaccgtgct attcgtgagc ctgaaatcga
      841 aaccattcaa gaatttttct tgaaacgtaa aattgataag acctctgtta atgaagccaa
      901 tatcaagaca ctctactcag agaaattaat tggaatttca atcccaatca agtaagaaaa
      961 ttgagtaaaa actcgatttg agagaaagtc caataagtct ttccataaca aaacgcatag
     1021 taacaagagt ttctacaccc actattatac gtttttatca ttttgaaatc tgctgctaat
     1081 caatgaagaa gcaaagatca aactaggcag ctagttacaa gttacgtaag cgcgtcataa
     1141 caaggtatct atcctaattc cccaacttcc agtatactag ataaaaaata attatcagag
     1201 gaaaggtatt gtactatgat gattgtacta agtgatttag gtcaagttca ccttgtttgt
     1261 ggcaagacag atatgaggca gggaatagac tcattagcct atgtagttaa aacccacttt
     1321 gaattggatc ctttctccgg tcaagtcttt ctcttttgtg gtggacgtaa agaccgcttt
     1381 aaagcccttt actgggatgg tcaaggattt tggctactat ataaacgctt tgagaacggc
     1441 agactgactt ggcccagtac agaaaaggat gtcaaagctc tcacatctga acaagtagac
     1501 tggcttatga agggcttttc tatcactccc caaatatagt ggatttaaac tagaatagta
     1561 cacctctact tctaaaacat tgttag
//
LOCUS       DAVBEO010000096         1455 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 009
            SAMEA1678075-rid20185393.denovo.096, whole genome shotgun sequence.
ACCESSION   DAVBEO010000096 DAVBEO010000000
VERSION     DAVBEO010000096.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678075
            Sequence Read Archive: ERR226392
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1455)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1455)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980207.1
            Genome Coverage       :: 150x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:50:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 72 of 147
            Pseudo Genes (incomplete)         :: 72 of 147
            Pseudo Genes (internal stop)      :: 42 of 147
            Pseudo Genes (multiple problems)  :: 32 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1455
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678075-rid20185393.denovo.096"
                     /strain="KS 009"
                     /db_xref="taxon:1313"
     gene            complement(412..804)
                     /gene="rpsI"
                     /locus_tag="VQ543_002099"
     CDS             complement(412..804)
                     /gene="rpsI"
                     /locus_tag="VQ543_002099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002942223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HET2612745.1"
                     /translation="MSQAQYAGTGRRKNAVARVRLVPGTGKITVNKKDVEEYIPHADL
                     RLVINQPFAVTSTVGSYDVFVNVVGGGYAGQSGAIRHGIARALLQVDPDFRDSLKRAG
                     LLTRDSRKVERKKPGLKKARKASQFSKR"
     gene            complement(824..1270)
                     /gene="rplM"
                     /locus_tag="VQ543_002100"
     CDS             complement(824..1270)
                     /gene="rplM"
                     /locus_tag="VQ543_002100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L13"
                     /protein_id="HET2612746.1"
                     /translation="MNKTTFMAKPGQVERKWYVVDATDVPLGRLSAVVASVLRGKNKP
                     TFTPHTDTGDFVIVINAEKVKLTGKKATDKIYYTHSNHPGGLKQISAGELRSKNAVRL
                     IEKSVKGMLPHNTLGRAQGMKLKVFVGAEHTHAAQQPEVLDISGLI"
BASE COUNT          420 a          290 c          279 g          466 t
ORIGIN      
        1 cccaaactct tcacacaaga gttctaactt acccattcta tggaatcttg cattatccat
       61 aatatagtag attgaaacta gaatagtaca cctctacttc taaaacattg ttagaattcg
      121 atttgactat cctcggtttg tcctattctt atttcacctt actataaaaa taaggtaaac
      181 ttttcaaaaa aacacgaaaa aagcacccat agggcaaacc tttgagtgct ttgaaacatt
      241 gatataattg tattgattag cgttttgagg caactgacct tgtcaggttg cagccacatt
      301 tgtaagcaac taaagtcgca acaactgtgt caattgcacc aatttagtaa gaaagtataa
      361 aaaaagaaca ccccgaaagg tgctctgtat aagtatagta attctttcga attaacgttt
      421 actaaattgt gatgctttac gagctttctt aagacctggt ttcttacgtt caactttacg
      481 tgagtcacgt gtaagaagtc ctgcgcgttt caatgaatcg cggaagtctg ggtctacttg
      541 aagaagggca cgagcgatac cgtgacggat agctcctgat tgaccagcgt atccaccacc
      601 tacaacgtta acgaaaacgt cgtatgaacc tacagttgaa gtaactgcga atggttggtt
      661 gatgacaaga cgaaggtcag catgtgggat gtactcttca acatcttttt tgttaacagt
      721 gattttacca gttcctggaa caaggcgaac gcgtgcaaca gcgtttttac gacgtccagt
      781 acctgcatat tgtgcttgtg acatacttta tttgttcctt tccttagata agtcctgaaa
      841 tgtcaagaac ttctggttgt tgtgcagcat gagtgtgctc agctccaaca aatactttca
      901 acttcatacc ttgagcgcgt ccaagtgtat tgtgtggaag cataccttta actgatttct
      961 caatcaaacg tactgcattt ttagaacgaa gttcacctgc agagatttgt ttcaatccac
     1021 ctgggtggtt tgagtgagtg tagtagattt tatcagttgc ttttttacca gtcaatttaa
     1081 ctttttcagc attgataaca atcacgaagt cacctgtatc agtgtgtggt gtaaatgttg
     1141 gtttgttttt tccgcgaagt acgctagcaa ctactgcaga aagacgtcca agtggtacat
     1201 cagttgcgtc aactacgtac catttacgtt caacttggcc tggtttagcc ataaatgttg
     1261 ttttgttcat gatttctcct atatatagtt cgatttttgt ttacggtgat gggtgttcct
     1321 tcccatcgaa aagtatttgg aaggttccgg ggcctttcaa atggggtaaa caataccgcc
     1381 tactatcata ccaaatttca cccctaaaag tcaatagata tgaaaaatat ttttcggtaa
     1441 cttctcaaag taact
//
LOCUS       DAVBEO010000097         1058 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 009
            SAMEA1678075-rid20185393.denovo.097, whole genome shotgun sequence.
ACCESSION   DAVBEO010000097 DAVBEO010000000
VERSION     DAVBEO010000097.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678075
            Sequence Read Archive: ERR226392
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1058)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1058)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980207.1
            Genome Coverage       :: 150x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:50:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 72 of 147
            Pseudo Genes (incomplete)         :: 72 of 147
            Pseudo Genes (internal stop)      :: 42 of 147
            Pseudo Genes (multiple problems)  :: 32 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1058
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678075-rid20185393.denovo.097"
                     /strain="KS 009"
                     /db_xref="taxon:1313"
     gene            complement(1..78)
                     /locus_tag="VQ543_002101"
                     /pseudo
     CDS             complement(1..78)
                     /locus_tag="VQ543_002101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155321.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            complement(527..925)
                     /locus_tag="VQ543_002102"
     CDS             complement(527..925)
                     /locus_tag="VQ543_002102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000428147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET2612747.1"
                     /translation="MENKESHKSQEIGNLIRVYNRSKREEAESEPLNLYVEDEKGNLL
                     AGLIAETFGNWLEIEYLFVKEELRGQGIGSKLLQQAESEAKNRNCCFAFVNTYQFQAP
                     DFYQKHGYKEVFSLQDYLYIRQRYYYQKNL"
BASE COUNT          321 a          199 c          158 g          380 t
ORIGIN      
        1 acgcttgatt tcagtgtgga tagtttgagg agcttttcca agtagagagg caatttctct
       61 atttgatttc cctttgttcg ccttttgtag tataatggtt ttgcatctct gtgcctttct
      121 tgtgtttgtg gttgaacaac aagtataaca caaaggtgtt ttcttatgcc tacaagagct
      181 ttcattattt ccattttctt ttggatttca ctctattctg aaaaacttgt gtatatttac
      241 tgaagctagc aagtcttacc tgtaaattta atgaaagcaa cacaaaatcc gagaggggaa
      301 tctcggatta atgtcaattt aaaaagatag agagttttta gtttaaataa attgttttaa
      361 aatatcaaca acatcacttc ttttcttaac ctgataagcc ttgattccta attttggggc
      421 tacgattata ttgtcctcaa tatcgtctag aaagacacaa tttctaggtt ataactggta
      481 tttatcgata gttactcata tatatcagtc cacctccata ctcaccttac agattctttt
      541 gataataata tctttgccta atgtagagat agtcttgcaa agaaaaaact tccttgtagc
      601 catgtttctg ataaaagtcc ggtgcctgga actggtaagt attgacaaag gcaaaacaac
      661 aatttcgatt cttagcttca ctttctgcct gttgcaatag ttttgaaccg attccttgcc
      721 ctcgcagttc ctcttttaca aacaaatact cgatttctag ccaatttcca aaagtctctg
      781 ctatcaaacc cgcaaggaga ttgccctttt catcttcgac ataaagatta agtggctcac
      841 tttcagcctc ttctcttttt gaacggttat aaacacgaat cagattccct atttcttgcg
      901 atttatgtga ttccttattt tccaatctaa agtataatga aatgaaataa aacatgcgca
      961 aatcgattaa ggaatttaat ctaatttcta acaatgtctt agaaatcaaa gtgtactatt
     1021 ttaacttcaa tgcactatac atctaatact caataaaa
//
LOCUS       DAVBEO010000098         1056 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 009
            SAMEA1678075-rid20185393.denovo.098, whole genome shotgun sequence.
ACCESSION   DAVBEO010000098 DAVBEO010000000
VERSION     DAVBEO010000098.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678075
            Sequence Read Archive: ERR226392
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1056)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1056)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980207.1
            Genome Coverage       :: 150x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:50:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 72 of 147
            Pseudo Genes (incomplete)         :: 72 of 147
            Pseudo Genes (internal stop)      :: 42 of 147
            Pseudo Genes (multiple problems)  :: 32 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1056
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678075-rid20185393.denovo.098"
                     /strain="KS 009"
                     /db_xref="taxon:1313"
     gene            105..>1056
                     /locus_tag="VQ543_002103"
     CDS             105..>1056
                     /locus_tag="VQ543_002103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HET2612748.1"
                     /translation="MQEHYTPKGKHLTIDNRRLIERWKNENKSNREIAGLLGKAPQTI
                     HNEVKRGTTLQQVRKGLYKKVYSADYAQTVYQFNRKRSVKKLILTKEIREKILHYHKQ
                     KFSPEMMVNKKQVKVGISTIYYWFHNGHLGLTKADMLYPRKRKGVKKQASPNFKPAGK
                     SIEERPDVINLRLENGHYEIDTVLLTKIKNYCLLVLTDRRSRHQIIRLIPNKTAESVN
                     QALTLLLGEHRILSITADNGSEFKRLSEVFPEEHIYYAHAYSSWERGSNENHNRLIRR
                     WLPKGTKKTTPKEVAFIENWINNYPKKCLDYKSPSEFLLGG"
BASE COUNT          373 a          189 c          220 g          274 t
ORIGIN      
        1 aggttcaagg gttcctgttg tcaaatgaaa tgtgatttaa ggtataagaa aacacctctg
       61 tgctatactt gttgttcacc acaaacacaa ggaaaggcac agagatgcaa gaacattata
      121 ccccaaaagg gaaacatttg acaatagata accgtcgctt gattgagcgg tggaagaatg
      181 aaaataagtc caatcgtgaa attgcaggct tgttaggaaa ggcgcctcaa acgattcata
      241 atgaagtcaa aagaggtaca actttacaac aagtgagaaa agggctatac aaaaaggtct
      301 attctgccga ttacgcacaa actgtttacc aattcaatcg aaaacggtcg gtgaaaaagt
      361 taattttaac aaaggaaatc agagagaaga tcttacacta tcataagcaa aaattttcgc
      421 ctgaaatgat ggttaacaag aagcaagtga aagttggtat ttcaaccatc tactactggt
      481 ttcataatgg tcatttagga ttgacgaagg ccgacatgct ttatcccaga aaaaggaaag
      541 gtgtcaagaa gcaagctagt ccgaacttta agccggcagg taaatctatc gaagaacgtc
      601 ctgacgttat taatcttcgc ttggaaaatg gtcattatga aattgatacc gtcctactga
      661 ctaagataaa aaattattgc ctgttagtct taaccgaccg gcggagcaga caccaaatta
      721 taaggttaat tccaaataaa actgctgaat ctgtcaatca ggcgcttacg ttactattag
      781 gggagcatcg tattctgtcc attactgcag ataatggttc ggagttcaaa cgattgtctg
      841 aggtatttcc tgaggaacat atctactacg cacatgctta ctcttcatgg gagagaggtt
      901 caaatgaaaa tcataatcga ttaattcgga gatggttacc taaaggaacc aagaaaacga
      961 ctccgaaaga agtagctttt atcgaaaatt ggattaacaa ctaccctaaa aaatgcttgg
     1021 actacaagtc gccaagtgaa tttcttttgg gtggct
//
LOCUS       DAVBEO010000099         1054 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 009
            SAMEA1678075-rid20185393.denovo.099, whole genome shotgun sequence.
ACCESSION   DAVBEO010000099 DAVBEO010000000
VERSION     DAVBEO010000099.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678075
            Sequence Read Archive: ERR226392
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1054)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1054)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980207.1
            Genome Coverage       :: 150x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:50:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 72 of 147
            Pseudo Genes (incomplete)         :: 72 of 147
            Pseudo Genes (internal stop)      :: 42 of 147
            Pseudo Genes (multiple problems)  :: 32 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1054
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678075-rid20185393.denovo.099"
                     /strain="KS 009"
                     /db_xref="taxon:1313"
     gene            <1..555
                     /locus_tag="VQ543_002104"
     CDS             <1..555
                     /locus_tag="VQ543_002104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001220748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HET2612749.1"
                     /translation="KDETTSYPIYEIPEAWRYIKFASLVNFRIGKTPPRSEATFWGTE
                     IPWVSISDMPISGYVTNTRESISKLALKSKKIDISPKGTLLMSFKLSIGKVAILDIPA
                     THNEAIISIFPYANKENIIRDYLMIFLPLISTLGDSKDAIKGKTLNSTSISELLIPIS
                     NHEEMKRIISKVDLLFQKVSQLFE"
     gene            complement(503..1048)
                     /locus_tag="VQ543_002105"
     CDS             complement(503..1048)
                     /locus_tag="VQ543_002105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001104691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HET2612750.1"
                     /translation="MNWVVIKIKDIFSINTGLSYKKGDLSINNKGVRIIRGGNIKPLE
                     FSLLDNDYYIDTQFISSEQVYLKHNQLITPVSTSLEHIGKFARIDKDYDGVVAGGFIF
                     QLTPFESSEIISKFLLFNLSSPLFYKQLKAITKLSGQALYNIPKTTLSELLIPLAPFE
                     EQELITQKVEKLFEKVNQLWK"
BASE COUNT          380 a          165 c          153 g          356 t
ORIGIN      
        1 aaagacgaaa caacctctta tcctatatat gaaatcccag aagcatggag atatattaaa
       61 tttgctagcc tagttaactt cagaatagga aaaactcctc cacgcagtga agctactttt
      121 tggggaactg aaataccttg ggtatctata tcagatatgc ctatatctgg ttatgtaact
      181 aatacgagag aatctatttc taaattagca ttaaaatcaa agaaaataga catttcacct
      241 aaaggaactt tattaatgag ttttaaatta tctattggaa aagttgccat attggatatt
      301 cctgccactc ataatgaagc cattatatcg atattcccct atgctaataa agaaaatatt
      361 atcagagatt acttaatgat atttttgcca cttatctcta ctttaggtga ttcaaaagat
      421 gctataaaag ggaaaacatt aaatagtacc agtatctccg aattattaat ccctatttct
      481 aatcatgaag agatgaaaag aatcatttcc aaagttgatt tactttttca aaaagtttct
      541 caactttttg agtaataagt tcctgttcct caaaaggagc taacggaatt aatagctcgc
      601 ttagtgtagt tttaggaata ttatataaag cttgacctga tagtttagtt attgctttca
      661 attgtttata aaataacgga gaggacaagt taaataatag aaattttgaa ataatctctg
      721 aactttcgaa tggtgttaat tggaaaataa atccaccagc cacaacacca tcatagtctt
      781 tatcgattct tgcaaacttt ccaatatgtt ctaaagaggt tgatacaggt gttattagct
      841 gattatgttt taaataaact tgctcagagg agatgaattg tgtatcaatg tagtaatcat
      901 tatccaacag agaaaattct aaaggcttaa tattaccacc acgtataatt ctaacacctt
      961 tattattaat gcttaaatcg cccttcttgt aagaaagacc tgtatttatt gaaaaaatat
     1021 cttttatttt tataacaacc caattcatag gtat
//
LOCUS       DAVBEO010000100         1035 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 009
            SAMEA1678075-rid20185393.denovo.100, whole genome shotgun sequence.
ACCESSION   DAVBEO010000100 DAVBEO010000000
VERSION     DAVBEO010000100.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678075
            Sequence Read Archive: ERR226392
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1035)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1035)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980207.1
            Genome Coverage       :: 150x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:50:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 72 of 147
            Pseudo Genes (incomplete)         :: 72 of 147
            Pseudo Genes (internal stop)      :: 42 of 147
            Pseudo Genes (multiple problems)  :: 32 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1035
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678075-rid20185393.denovo.100"
                     /strain="KS 009"
                     /db_xref="taxon:1313"
     gene            complement(<1..990)
                     /gene="ltrA"
                     /locus_tag="VQ543_002106"
     CDS             complement(<1..990)
                     /gene="ltrA"
                     /locus_tag="VQ543_002106"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HET2612751.1"
                     /translation="MSKLLDKILSRDNMLEAYNQVKSNKGSAGIDGITIEEMDGYLRQ
                     NWRLTKELIKQRKYKPQPVLRVEIPKPNGGIRQLGIPTVMDRMIQQAIVQVISPICEP
                     HFSDTSYGFRPNRSCEKAIMKLLEYLNDGYEWIVDIDLEKFFDTVPQDRLMSLVHNII
                     EDGDTESLIRKYLHSGVIINGQRYKTLVGTPQGGNLSPLLSNIMLNELDKELEKRGLR
                     FVRYADDCVITVGSEAAAKRVMYSVSRFIEKRLGLKVNMTKTKITRPRELKYLGFGFW
                     KSSDGWKSRPHQDSVWRFKLKLKKLTQRKWSIDLTRRIEQLNLSIRGWINYFSL"
BASE COUNT          270 a          226 c          183 g          356 t
ORIGIN      
        1 caatgagaaa tagtttatcc atcctcgaat agacaaattc agttgctcaa tacgtcttgt
       61 taggtctata ctccatttcc tctgtgttag tttcttcaat ttaagcttaa atctccaaac
      121 actatcttga tgtggacgac ttttccaacc atctgatgat ttccagaacc cgaaacctag
      181 atatttcaac tctcttggtc tggtaatctt agtcttggtc atgtttactt tcagacctag
      241 ccgtttctca ataaaacgac tgactgaata catcacacgc ttagcggctg cctcgcttcc
      301 gaccgtaatc acacaatcgt ctgcgtagcg aacaaatcga agccctctct tttctaattc
      361 cttgtccaat tcattaagca tgatattgga taagagagga gataaatttc ctccctgtgg
      421 cgtgccaact agcgttttat aacgttgacc gttaatgata acacctgaat gaagatattt
      481 acgaatcaag gattccgtat ctccgtcttc gataatgtta tgtactaagg acatcaatct
      541 atcttgagga actgtatcga aaaatttctc taggtctatg tccactatcc actcatagcc
      601 gtcatttaag tactctaaga gcttcatgat ggctttttca catgacctat ttggtctgaa
      661 tccatagctc gtatctgaga aatggggttc acaaataggg ctaataactt gaacaatggc
      721 ctgttgaatc attctatcca taactgttgg aattcctagt tggcggatgc ctccgtttgg
      781 tttgggaatc tcaactctaa gaactggttg aggcttatat tttctctgtt ttatcagttc
      841 cttagtcagg cgccagtttt gtctgagata gccatccatc tcttcgatag taattccatc
      901 aatcccagct gagcctttat tagattttac ttgattgtag gcttcaagca tattgtcgcg
      961 tgataatatt ttatctagca attttgacat gtgcctattc ctttcttgtt ttggtgcctg
     1021 agggacatct tatat
//
LOCUS       DAVBEO010000101          922 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 009
            SAMEA1678075-rid20185393.denovo.101, whole genome shotgun sequence.
ACCESSION   DAVBEO010000101 DAVBEO010000000
VERSION     DAVBEO010000101.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678075
            Sequence Read Archive: ERR226392
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 922)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 922)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980207.1
            Genome Coverage       :: 150x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:50:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 72 of 147
            Pseudo Genes (incomplete)         :: 72 of 147
            Pseudo Genes (internal stop)      :: 42 of 147
            Pseudo Genes (multiple problems)  :: 32 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..922
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678075-rid20185393.denovo.101"
                     /strain="KS 009"
                     /db_xref="taxon:1313"
     gene            122..590
                     /locus_tag="VQ543_002107"
                     /pseudo
     CDS             122..590
                     /locus_tag="VQ543_002107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001817843.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
BASE COUNT          336 a          139 c          172 g          275 t
ORIGIN      
        1 gagaagagga ttgccatctt ctccattttt atgtgcagag ttatagtggc ttgatgctgg
       61 gaaagtacac tgtgactgct aaaacattcc tagaagctgc tttgatttcc ctaatctatt
      121 tatgcaaatt ttatgttatt ttactataac agttgttgct aagccaaata atagtgggga
      181 agttcattta gacgtaagca ttgaagataa tcagggaggt agtgggtata atttcagttc
      241 tgtttcaagt agctcacaaa cagctaaata tgaaggaact ggttataata acaattcatc
      301 attatatata acgattgata aaacgtctga tgcaacagct cttttgaaat taaagttgaa
      361 taatgttgat aatcaacctg ctactgaagt tcctagttca ggaattactg taaaattaaa
      421 tgctaaagat aatgctggaa actggacaag tgcttcgaat aaagacaagt gcttcgaata
      481 aaaaagaaat aacagtaaaa attgtttctg ctaaaccgac atatccagac aaaatcttag
      541 tgaaaaatcc tgataatata aaagatacag aaaaaaatgc cattattgaa aaattgaaag
      601 aggcaaataa aaatcatcca gcaggagctc caacctttgc taaaggtgaa ggagagcatg
      661 caaatgatat tgtagcaact tattcagatg gtacaactta ttatgtaccg ttaaatgatg
      721 tgacaaaata tgcgaggtag tggctgtacc actcacttat tcacctcccc gtgatttgta
      781 gtagtgatag gctttctcac tattattata aaacaaaata aagatcacaa cactttttca
      841 ttctgtgttg tgccttgagt gaaacgaaag gaatgaatta taaatatgaa aagtatagtc
      901 actagcatag atgagcgctt gc
//
LOCUS       DAVBEO010000102          830 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 009
            SAMEA1678075-rid20185393.denovo.102, whole genome shotgun sequence.
ACCESSION   DAVBEO010000102 DAVBEO010000000
VERSION     DAVBEO010000102.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678075
            Sequence Read Archive: ERR226392
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 830)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 830)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980207.1
            Genome Coverage       :: 150x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:50:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 72 of 147
            Pseudo Genes (incomplete)         :: 72 of 147
            Pseudo Genes (internal stop)      :: 42 of 147
            Pseudo Genes (multiple problems)  :: 32 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..830
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678075-rid20185393.denovo.102"
                     /strain="KS 009"
                     /db_xref="taxon:1313"
     gene            21..830
                     /locus_tag="VQ543_002108"
                     /pseudo
     CDS             21..830
                     /locus_tag="VQ543_002108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558050.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5-like element IS1515 family transposase"
BASE COUNT          266 a          174 c          162 g          228 t
ORIGIN      
        1 aaaagtgtta tactattttt atggaaacag tatacgacaa agcacaaaaa cttaactcaa
       61 aaaacttcaa actattgatt ggtgtcaaaa aggaaacctt tcaactcatg ctagaacacc
      121 tgaattcagc ctatcagatt cagcaccgaa aaggtggacg tccacgtagt ctgcccatgg
      181 aagaccagct cattatgacc ctccgttact tgcgatatta tcccactcag cgtctgctgg
      241 cctttgattt tggcgtcggt gtagctacgg taaatgccat catcacttgg gtggaggata
      301 cacttcgtgc gtcaggtagc tttgatttgg accatttaga agccccgagt gctgctgtgg
      361 ctattgacgt gaccgaaagt ccgattcagc gtccaaaaaa aaccaaagca aaaattattc
      421 tggtaaaaag aaacgacaca ccttaaaaac tcaaattatg ctggatttga cgacacataa
      481 agtctgtcaa atggcctttt ctgacggaca tacgcatgat tttactctct tcaaagaaag
      541 tattggacaa agtttgcctg aaacgacgct tgcctttgtt gacctaggtt atttaggcat
      601 cttgaaattt catgagaata ctttcattcc tgctaaaaat tccaaaaatc gccgcctgag
      661 tgaggatgat aagcagttaa ataaagagat gtcagcgata cgaattgaaa ttgaacattt
      721 taacgctaaa ttcaagacct tccaaatcat gtcagtccct tatcgtaacc gcagaaaacg
      781 tttcgagtta cgggcggaat taatttgtgc catcatcaat tatgaagtga
//
LOCUS       DAVBEO010000103          767 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 009
            SAMEA1678075-rid20185393.denovo.103, whole genome shotgun sequence.
ACCESSION   DAVBEO010000103 DAVBEO010000000
VERSION     DAVBEO010000103.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678075
            Sequence Read Archive: ERR226392
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 767)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 767)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980207.1
            Genome Coverage       :: 150x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:50:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 72 of 147
            Pseudo Genes (incomplete)         :: 72 of 147
            Pseudo Genes (internal stop)      :: 42 of 147
            Pseudo Genes (multiple problems)  :: 32 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..767
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678075-rid20185393.denovo.103"
                     /strain="KS 009"
                     /db_xref="taxon:1313"
     gene            complement(<1..>767)
                     /locus_tag="VQ543_002109"
     CDS             complement(<1..>767)
                     /locus_tag="VQ543_002109"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2612752.1"
                     /translation="ALVLAEADALVDAEAEALVDAEAEALVDADSEADVLAEADALVD
                     ADSDALVDAEAEALVDADAEALVLAEADALVLAEAEALVDAEAEALVLAEADALVEAE
                     ADALVDAEAEALVLAEADALVDADADALVDADSDAEILAEAEAEALVDAEADALVLAE
                     ADALVLAEADALVDADSEADVLAEAEALVDAEAEALVEAEADALVDAEADALVLAEAE
                     ALVDAEAEALVLAEAEALVDAEAEALVDAEADALVDA"
BASE COUNT          190 a          246 c          175 g          156 t
ORIGIN      
        1 tcagcgtcga caagtgcgtc agcctcagca tcgacaagcg cttcagcttc agcgtcgaca
       61 agtgcttcgg cttcagcaag caccagtgcc tcggcttcag cgtcgacaag tgcctcagct
      121 tcagcaagta ccagtgcgtc agcctcagca tcaacgagtg cgtcggcttc agcctcaacg
      181 agtgcttcag cttcagcatc aacgagtgct tcggcttcag caagcacatc agcttctgaa
      241 tcagcatcaa ccagtgcatc agcctcagca agcaccagtg cgtcggcttc agcaagtaca
      301 agtgcgtcag cctcagcatc aacaagtgcc tcagcttcag cctcagcaag tatctcagcg
      361 tctgaatctg catcaaccag tgcgtcagca tccgcatcaa cgagtgcatc agcttcagca
      421 agcaccagtg cttcagcttc agcatcaaca agtgcatcag cttcggcctc aacaagtgcg
      481 tcagcttcag caagcaccag tgcttcggct tcagcgtcga caagtgcctc agcttcagca
      541 agtaccagtg cgtcagcctc agcaagtact agcgcctcag catcagcgtc aacaagtgct
      601 tcggcttcag cgtcaacgag tgcgtctgag tcagcatcaa cgagtgcgtc agcctcagca
      661 agcacatcag cttctgaatc cgcatcaaca agtgcttcag cctcagcgtc aacaagtgct
      721 tcagcttcag catcaaccag tgcatcagct tcagcaagta ctagcgc
//
LOCUS       DAVBEO010000104          692 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 009
            SAMEA1678075-rid20185393.denovo.104, whole genome shotgun sequence.
ACCESSION   DAVBEO010000104 DAVBEO010000000
VERSION     DAVBEO010000104.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678075
            Sequence Read Archive: ERR226392
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 692)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 692)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980207.1
            Genome Coverage       :: 150x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:50:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 72 of 147
            Pseudo Genes (incomplete)         :: 72 of 147
            Pseudo Genes (internal stop)      :: 42 of 147
            Pseudo Genes (multiple problems)  :: 32 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..692
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678075-rid20185393.denovo.104"
                     /strain="KS 009"
                     /db_xref="taxon:1313"
     gene            complement(74..147)
                     /locus_tag="VQ543_002110"
     tRNA            complement(74..147)
                     /locus_tag="VQ543_002110"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(111..113),aa:Arg,seq:acg)
     gene            complement(157..242)
                     /locus_tag="VQ543_002111"
     tRNA            complement(157..242)
                     /locus_tag="VQ543_002111"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(206..208),aa:Leu,seq:taa)
     gene            complement(250..321)
                     /locus_tag="VQ543_002112"
     tRNA            complement(250..321)
                     /locus_tag="VQ543_002112"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(287..289),aa:Gly,seq:gcc)
     gene            complement(344..416)
                     /locus_tag="VQ543_002113"
     tRNA            complement(344..416)
                     /locus_tag="VQ543_002113"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(381..383),aa:Thr,seq:tgt)
     gene            complement(435..516)
                     /locus_tag="VQ543_002114"
     tRNA            complement(435..516)
                     /locus_tag="VQ543_002114"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(480..482),aa:Leu,seq:tag)
     gene            complement(522..594)
                     /locus_tag="VQ543_002115"
     tRNA            complement(522..594)
                     /locus_tag="VQ543_002115"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(559..561),aa:Lys,seq:ttt)
     gene            complement(619..691)
                     /locus_tag="VQ543_002116"
     tRNA            complement(619..691)
                     /locus_tag="VQ543_002116"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(656..658),aa:Asp,seq:gtc)
BASE COUNT          179 a          205 c          149 g          159 t
ORIGIN      
        1 cgaacctgcg acaccttggt cccaaaccaa gtactctacc aagctgagct acttcccgag
       61 ttaaatagaa aaatgcaccc tagaggagtc gaacctctaa ccgcctgatt cgtagtcagg
      121 tactctatcc agttgagcta agggtgctcc atattatgcc gaggaccgga atcgaaccgg
      181 tacgatcgtt accaatcgca ggattttaag tcctgtgcgt ctgccagttc cgccaccccg
      241 gcctctctaa gcgaacgacg ggattcgaac ccgcgacccc caccttggca aggtggtgtt
      301 ctaccactga actacgttcg cactgttttc ttctatctaa aaatgccggc tacatgactt
      361 gaacacgcga ccctctgatt acaaatcaga tgctctacca actgagctaa gccggctcat
      421 ttgttatatc ttaatgcggg ttaagggact tgaaccccca cgccgttaag cgccagatcc
      481 taaatctggt gcgtctgcca attccgccaa acccgcatat atgacccgta ctgggctcga
      541 accagtgacc cattgattaa aagtcaattg ctctaccaac tgagctaacg agtctaaaat
      601 aacttgcgtt accttaaacg gtcccgacgg gaatcgaacc cgcgatcttc gccgtgacag
      661 ggcgacgtga taaccgctac actacgggac ct
//
LOCUS       DAVBEO010000105          634 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 009
            SAMEA1678075-rid20185393.denovo.105, whole genome shotgun sequence.
ACCESSION   DAVBEO010000105 DAVBEO010000000
VERSION     DAVBEO010000105.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678075
            Sequence Read Archive: ERR226392
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 634)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 634)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980207.1
            Genome Coverage       :: 150x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:50:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 72 of 147
            Pseudo Genes (incomplete)         :: 72 of 147
            Pseudo Genes (internal stop)      :: 42 of 147
            Pseudo Genes (multiple problems)  :: 32 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..634
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678075-rid20185393.denovo.105"
                     /strain="KS 009"
                     /db_xref="taxon:1313"
     gene            complement(1..634)
                     /locus_tag="VQ543_002117"
                     /pseudo
     CDS             complement(1..634)
                     /locus_tag="VQ543_002117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="frameshifted; incomplete; missing N-terminus and
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
BASE COUNT          198 a          116 c          129 g          191 t
ORIGIN      
        1 taaaatctct ttattggtta aatgcatacg aaaagtaggg cgataaaaat gtttatcgct
       61 gagtttacga ctatcctgtt gtatgagctt ccagtagcgc ttgatagcct tgtattcatg
      121 agactttcga tccaattgat tcatgatttg aacacgcaca cgactcatag cacggctaag
      181 atgttgtaca atgtgaaagc gatccaacac gattttagca catgggaaaa gttgtctagc
      241 taagtcatag taaggactaa acatatccat agtaataatt ttgacgcgac atcggacggc
      301 tctatcatat ttaagaaagt gatctcggat gacagcttgt gttctaccct caagaacagt
      361 gatgatattg agattgttaa aatcttgcgc aatgaagctc atctccatct cccgattgaa
      421 acagtcactc cccggactgt ttcaacgtcc caagacataa tctcaggcag atttctaaaa
      481 ttacactcaa agtggaagtc attgagctta cgaataacag ttgaagttga gatggaaagc
      541 tgatgggcaa tatcagtcat agaaatcttt tcaattaact tttgagcaat cttttggttg
      601 atgatacgag ggatttggtg attattcttg acga
//
LOCUS       DAVBEO010000106          633 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 009
            SAMEA1678075-rid20185393.denovo.106, whole genome shotgun sequence.
ACCESSION   DAVBEO010000106 DAVBEO010000000
VERSION     DAVBEO010000106.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678075
            Sequence Read Archive: ERR226392
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 633)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 633)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980207.1
            Genome Coverage       :: 150x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:50:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 72 of 147
            Pseudo Genes (incomplete)         :: 72 of 147
            Pseudo Genes (internal stop)      :: 42 of 147
            Pseudo Genes (multiple problems)  :: 32 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..633
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678075-rid20185393.denovo.106"
                     /strain="KS 009"
                     /db_xref="taxon:1313"
     gene            complement(1..633)
                     /locus_tag="VQ543_002118"
                     /pseudo
     CDS             complement(1..633)
                     /locus_tag="VQ543_002118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677188.1"
                     /note="frameshifted; internal stop; incomplete; missing
                     N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
BASE COUNT          204 a          113 c          128 g          188 t
ORIGIN      
        1 ttgtcctcaa taagtccgaa aaatttctct ggttccttat tctggaaatg aaaaagcaag
       61 agctgataga gttgatagtg gtgtttcaag tcttccgaat aactcaaaag cttgtttaaa
      121 atctctttat tggttcaatg catacgaaaa gtaggacgat aaaaatgttt atcactcagt
      181 ttacgactat cctgttgaat gagtttccag tagcgcttga tagccttgta ttcatgggat
      241 tttcgatgaa actgatttat gatttgaaca cgcacacgac tcatagcacg gctaagatgt
      301 tgtacaatgt gaaagcgatc caacacgatt ttagcattcg ggagtgaaac agtctgggag
      361 actgtttcag cctgagccta gaaatttgaa agcgaaactg tttagccaag tcatagtaag
      421 ggctaaacat atccatagta atgattttga cgcgacatcg gacaactcta tcgtagcgaa
      481 gaaagtgatt tcgaatgata gcttgtgttc taccctcaag aacagtgatg atattgagat
      541 tgttaaaatc ttgcgcaatg aagctcatct ttccctttgt aaaagcatac tcatcccaag
      601 acataatctc aggaagacaa gaaaaatcat gtt
//
LOCUS       DAVBEO010000107          611 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 009
            SAMEA1678075-rid20185393.denovo.107, whole genome shotgun sequence.
ACCESSION   DAVBEO010000107 DAVBEO010000000
VERSION     DAVBEO010000107.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678075
            Sequence Read Archive: ERR226392
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 611)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 611)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980207.1
            Genome Coverage       :: 150x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:50:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 72 of 147
            Pseudo Genes (incomplete)         :: 72 of 147
            Pseudo Genes (internal stop)      :: 42 of 147
            Pseudo Genes (multiple problems)  :: 32 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..611
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678075-rid20185393.denovo.107"
                     /strain="KS 009"
                     /db_xref="taxon:1313"
     gene            complement(189..>611)
                     /locus_tag="VQ543_002119"
     CDS             complement(189..>611)
                     /locus_tag="VQ543_002119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine motif-containing protein"
                     /protein_id="HET2612753.1"
                     /translation="KPNEEKPQTEKPEEDKEHDEVSEPTHPESDEKENHAGLNPSADN
                     LYKPSTDTEETEEEAEDTTDEAEIPQVEHSVINAKIAEAEALLEKVTDSSIRQNAVET
                     LTGLKSSLLLGTKDNNTISAEVDSLLALLKESQPTPIQ"
BASE COUNT          155 a          121 c           93 g          242 t
ORIGIN      
        1 gatgaagttt tttctcaact tcttttactt tattaaatag ttttctaaac cggttattta
       61 accatttaat taaccagtaa atagtttact atttaaaatt acttttgtca agtttctgtt
      121 acgtttttct aaaaaagaga agtaacacga aaggttactt ctccataaaa tatgctccat
      181 tcattttact actgtatagg agtcggttga ctttctttta acaaagccaa gagactatct
      241 acttctgctg aaatagtgtt attatctttc gttccgagaa gaagactact ttttagacca
      301 gtcaatgtct ccacagcatt ttgtctaata ctagaatctg ttactttttc tagcaaggcc
      361 tccgcctctg ctatcttagc gttaataaca gaatgctcta cttgaggaat ttcagcctca
      421 tctgtagtat cttcagcttc ttcctctgtc tcttccgtat cagtgcttgg tttataaaga
      481 ttatctgctg aaggatttaa accagcgtga ttctcttttt catcagattc agggtgagtt
      541 ggctcactta cttcatcatg ttccttatct tcctcaggtt tttctgtctg aggtttctcc
      601 tcgtttggtt t
//
LOCUS       DAVBEO010000108          541 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 009
            SAMEA1678075-rid20185393.denovo.108, whole genome shotgun sequence.
ACCESSION   DAVBEO010000108 DAVBEO010000000
VERSION     DAVBEO010000108.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678075
            Sequence Read Archive: ERR226392
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 541)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 541)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980207.1
            Genome Coverage       :: 150x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:50:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 72 of 147
            Pseudo Genes (incomplete)         :: 72 of 147
            Pseudo Genes (internal stop)      :: 42 of 147
            Pseudo Genes (multiple problems)  :: 32 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..541
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678075-rid20185393.denovo.108"
                     /strain="KS 009"
                     /db_xref="taxon:1313"
     gene            1..541
                     /locus_tag="VQ543_002120"
                     /pseudo
     CDS             1..541
                     /locus_tag="VQ543_002120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="frameshifted; internal stop; incomplete; missing
                     N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
BASE COUNT          209 a           90 c          114 g          128 t
ORIGIN      
        1 ataaagtctg acatgaaggc tagactaaag atagagtttc tcttgaatac ggtctcccaa
       61 gtcgtacgat acttcttaac tggctagcac aatacaggaa aaacgggtat actattgttg
      121 agaaaccaag agggagagta cctaaaatgg gacgtaagcc aagaacgaga cctgaagaga
      181 ggacagaatt agaacgtctt caagcagcaa atgagtacct gagagcggag aatgccatcc
      241 taaaaaagtt aagagaactc cgattgaagg aggaaaaaga gaaagaagaa agacagaaat
      301 tattcaagaa ttaatgactg agttttcgtt agatcttctt ctaaaagcca ttaaactagc
      361 tcgttcgacc tactactatc acttgaaaca gctagacaaa acagataagg accaagagct
      421 taaagctgaa attcaatcca tttttatcga acacaaggga aattatggtt atcgtcgaat
      481 ttatttagaa ctaagaaatc gtgcttatct ggtaaatcat aaaagagttc aaggcttgat
      541 g
//
LOCUS       DAVBEO010000109          497 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 009
            SAMEA1678075-rid20185393.denovo.109, whole genome shotgun sequence.
ACCESSION   DAVBEO010000109 DAVBEO010000000
VERSION     DAVBEO010000109.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678075
            Sequence Read Archive: ERR226392
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 497)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 497)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980207.1
            Genome Coverage       :: 150x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:50:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 72 of 147
            Pseudo Genes (incomplete)         :: 72 of 147
            Pseudo Genes (internal stop)      :: 42 of 147
            Pseudo Genes (multiple problems)  :: 32 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..497
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678075-rid20185393.denovo.109"
                     /strain="KS 009"
                     /db_xref="taxon:1313"
     gene            <1..>497
                     /locus_tag="VQ543_002121"
     CDS             <1..>497
                     /locus_tag="VQ543_002121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001815935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2612754.1"
                     /translation="STSASASASTSASASASTSASASASTSASASASTSASESASTSA
                     SASASTSASASASTSASESASISASASASTSASESASTSASASASTSASASASTSASA
                     SASTSASASASTSASASASTSASASASTSASASASTSASASASTSASASASTSASASA
                     STSASA"
BASE COUNT          122 a          162 c          112 g          101 t
ORIGIN      
        1 tcaaccagcg cctcagcttc agcatcaacg agtgcgtcgg cttcagcatc aacgagtgca
       61 tcggcttcag catcaacgtc tgcctcagct tcagcgtcaa ccagtgcctc tgaatcggca
      121 tcaaccagtg cttcagcctc agcatcgaca agcgcttcgg cttcagcaag tacatcagct
      181 tctgaatctg catcaataag tgcgtcggct tcagcgtcaa ccagtgcctc tgaatcggca
      241 tcaaccagtg cttcagcctc agcatcaacg agtgcttcgg cttcagcaag tacaagtgcg
      301 tcagcttcag caagcacaag tgcgtcagct tcagcatcaa cgagcgcctc ggcttcagca
      361 agcaccagtg cgtcagcttc agcatcaacg agtgcctcgg cctcagcaag tacaagtgcg
      421 tcagcctcag catcaaccag tgcatcagcc tcagcaagta ccagtgcatc agcttccgca
      481 tcaacgagtg catcagc
//
LOCUS       DAVBEO010000110          451 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 009
            SAMEA1678075-rid20185393.denovo.110, whole genome shotgun sequence.
ACCESSION   DAVBEO010000110 DAVBEO010000000
VERSION     DAVBEO010000110.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678075
            Sequence Read Archive: ERR226392
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 451)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 451)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980207.1
            Genome Coverage       :: 150x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:50:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 72 of 147
            Pseudo Genes (incomplete)         :: 72 of 147
            Pseudo Genes (internal stop)      :: 42 of 147
            Pseudo Genes (multiple problems)  :: 32 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..451
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678075-rid20185393.denovo.110"
                     /strain="KS 009"
                     /db_xref="taxon:1313"
     gene            complement(123..196)
                     /locus_tag="VQ543_002122"
     tRNA            complement(123..196)
                     /locus_tag="VQ543_002122"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(160..162),aa:Asn,seq:gtt)
     gene            complement(202..317)
                     /gene="rrf"
                     /locus_tag="VQ543_002123"
     rRNA            complement(202..317)
                     /gene="rrf"
                     /locus_tag="VQ543_002123"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
BASE COUNT          135 a          106 c           73 g          137 t
ORIGIN      
        1 tattgaatat gccataaaaa gattatacca cattgtgtac tatttttggt tcattttact
       61 ataacacgaa atagattatt attacataac aaaaaagagg tctaaacctc ttaactaaat
      121 tactccgcca gtaggactcg aacctacgac atcatgatta acagtcatgc gctactacca
      181 actgagctat ggcggattaa agctaagcga cttccctatc tcacaggggg caacccccaa
      241 ctacttccgg cgttctaggg cttaacttct gtgttcggca tgggtacagg tgtatctcct
      301 aggctatcgt cacttaactc tgagtaatac ctactcaaaa ttgaatatct attcaattca
      361 agaaaaccgt tcgctttcat attctcagtt actttggata agtcctcgag ctattagtat
      421 tagtccgcta catgtgtcgc cacacttcca c
//
LOCUS       DAVBEO010000111          393 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 009
            SAMEA1678075-rid20185393.denovo.111, whole genome shotgun sequence.
ACCESSION   DAVBEO010000111 DAVBEO010000000
VERSION     DAVBEO010000111.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678075
            Sequence Read Archive: ERR226392
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 393)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 393)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980207.1
            Genome Coverage       :: 150x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:50:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 72 of 147
            Pseudo Genes (incomplete)         :: 72 of 147
            Pseudo Genes (internal stop)      :: 42 of 147
            Pseudo Genes (multiple problems)  :: 32 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..393
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678075-rid20185393.denovo.111"
                     /strain="KS 009"
                     /db_xref="taxon:1313"
     gene            <1..>393
                     /locus_tag="VQ543_002124"
     CDS             <1..>393
                     /locus_tag="VQ543_002124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HET2612755.1"
                     /translation="YLHLWELSDWDQEGMLCLHELISREEGLVDDIPRLRKYFKTKFR
                     NRILDYIRKQESQKRRYDKEPYEEVGEISHRISEGGLWLDDYYLFHETLRDYRNKQSK
                     EKQEELERVLSNERFRGRQRVLRDLRIVF"
BASE COUNT          143 a           57 c           93 g          100 t
ORIGIN      
        1 taccttcatt tatgggaatt gtcggattgg gaccaagaag gcatgctctg cttacatgaa
       61 ttgattagta gagaagaagg actggtagac gatattccac gtttaaggaa atatttcaaa
      121 accaagtttc gaaatcgaat tttagactat atccgtaagc aggaaagtca gaagcgtaga
      181 tacgataaag aaccctatga agaagtggga gagatcagtc atcgtataag tgaggggggt
      241 ctctggctag atgattatta tctctttcat gaaacactaa gagattatag aaacaaacaa
      301 agtaaagaga aacaagaaga actagaacgc gtcttaagca atgaacgatt tcgagggcgt
      361 caaagagtat taagagactt acgcattgtg ttt
//
LOCUS       DAVBEO010000112          392 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 009
            SAMEA1678075-rid20185393.denovo.112, whole genome shotgun sequence.
ACCESSION   DAVBEO010000112 DAVBEO010000000
VERSION     DAVBEO010000112.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678075
            Sequence Read Archive: ERR226392
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 392)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 392)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980207.1
            Genome Coverage       :: 150x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:50:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 72 of 147
            Pseudo Genes (incomplete)         :: 72 of 147
            Pseudo Genes (internal stop)      :: 42 of 147
            Pseudo Genes (multiple problems)  :: 32 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..392
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678075-rid20185393.denovo.112"
                     /strain="KS 009"
                     /db_xref="taxon:1313"
     gene            283..>392
                     /locus_tag="VQ543_002125"
     CDS             283..>392
                     /locus_tag="VQ543_002125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIBC"
                     /protein_id="HET2612756.1"
                     /translation="MVLDYFFDKNLVFCLEADNQEQLFDQVATLLEEREIV"
BASE COUNT          143 a           53 c           70 g          126 t
ORIGIN      
        1 ggttacgata tgatcactga cttcgtcagt cttatctaca acctcaaaac tgtgttttga
       61 gcaacctgcg gctagcttcc tagtttgctc tttgattttc attgagtatt agaacagaaa
      121 aaatacttgg agtatttgtt tgtgtgttta tttttatata acaaactata aacaaaacaa
      181 aaatataaaa aaagagacaa aaaagaacag aaagcaattg acaacggttt catatagtgt
      241 tatacttatg gcataaagtt aatggaaaga agggaaaaac ttatggtatt agattatttc
      301 tttgacaaaa accttgtgtt ttgcttagaa gcggataatc aagaacaact ctttgatcag
      361 gttgcaactt tattggaaga acgagaaatt gt
//
LOCUS       DAVBEO010000113          292 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 009
            SAMEA1678075-rid20185393.denovo.113, whole genome shotgun sequence.
ACCESSION   DAVBEO010000113 DAVBEO010000000
VERSION     DAVBEO010000113.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678075
            Sequence Read Archive: ERR226392
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 292)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 292)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980207.1
            Genome Coverage       :: 150x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:50:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 72 of 147
            Pseudo Genes (incomplete)         :: 72 of 147
            Pseudo Genes (internal stop)      :: 42 of 147
            Pseudo Genes (multiple problems)  :: 32 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..292
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678075-rid20185393.denovo.113"
                     /strain="KS 009"
                     /db_xref="taxon:1313"
     gene            51..>292
                     /locus_tag="VQ543_002126"
     rRNA            51..>292
                     /locus_tag="VQ543_002126"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
BASE COUNT           90 a           54 c           81 g           67 t
ORIGIN      
        1 gaaaaaaaca ataaatctgt cagtgacaga aatgagtgag aactcaaact tttaatgaga
       61 gtttgatcct ggctcaggac gaacgctggc ggcgtgccta atacatgcaa gtagaacgct
      121 gaaggaggag cttgcttctc tggatgagtt gcgaacgggt gagtaacgcg taggtaacct
      181 gcctggtagc gggggataac tattggaaac gatagctaat accgcataag agtagatgtt
      241 gcatgacatt tgcttaaaag gtgcacttgc atcactacca gatggacctg cg
//
LOCUS       DAVBEO010000114          288 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 009
            SAMEA1678075-rid20185393.denovo.114, whole genome shotgun sequence.
ACCESSION   DAVBEO010000114 DAVBEO010000000
VERSION     DAVBEO010000114.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678075
            Sequence Read Archive: ERR226392
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 288)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 288)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980207.1
            Genome Coverage       :: 150x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:50:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 72 of 147
            Pseudo Genes (incomplete)         :: 72 of 147
            Pseudo Genes (internal stop)      :: 42 of 147
            Pseudo Genes (multiple problems)  :: 32 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..288
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678075-rid20185393.denovo.114"
                     /strain="KS 009"
                     /db_xref="taxon:1313"
     gene            <1..>288
                     /locus_tag="VQ543_002127"
     CDS             <1..>288
                     /locus_tag="VQ543_002127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="histidine motif-containing protein"
                     /protein_id="HET2612757.1"
                     /translation="NRVKAAKKVPLDRMPYNLQYTVEVKNGSLIIPHYDHYHNIKFEW
                     FDEGLYEAPKGYTLEDLLATVKYYVEHPNERPHSDNGFGNASDHVQRNKNG"
BASE COUNT           93 a           59 c           59 g           77 t
ORIGIN      
        1 caaccgcgtg aaagcagcta agaaggtgcc acttgatcgt atgccttaca atcttcaata
       61 tactgtagaa gtcaaaaacg gtagtttaat catacctcat tatgaccatt accataacat
      121 caaatttgag tggtttgacg aaggccttta tgaggcacct aaggggtata ctcttgagga
      181 tcttttggcg actgtcaagt actatgtcga acatccaaac gaacgtccgc attcagataa
      241 tggttttggt aacgctagcg accatgttca aagaaacaaa aatggtca
//
LOCUS       DAVBEO010000115          277 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 009
            SAMEA1678075-rid20185393.denovo.115, whole genome shotgun sequence.
ACCESSION   DAVBEO010000115 DAVBEO010000000
VERSION     DAVBEO010000115.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678075
            Sequence Read Archive: ERR226392
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 277)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 277)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980207.1
            Genome Coverage       :: 150x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:50:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 72 of 147
            Pseudo Genes (incomplete)         :: 72 of 147
            Pseudo Genes (internal stop)      :: 42 of 147
            Pseudo Genes (multiple problems)  :: 32 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..277
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678075-rid20185393.denovo.115"
                     /strain="KS 009"
                     /db_xref="taxon:1313"
     gene            <1..>277
                     /locus_tag="VQ543_002128"
     CDS             <1..>277
                     /locus_tag="VQ543_002128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HET2612758.1"
                     /translation="QRIIEAIESALEKVDEYAESYNRLEQLDKEFPDKLKKSILQYAM
                     QGKLVEQDPNDESVEVLLEKIRAEKQKLFEEGKIKKKDLDISIVSQG"
BASE COUNT          126 a           37 c           47 g           67 t
ORIGIN      
        1 aacaacgcat aatagaagca atcgaatcag ctttagaaaa agtagatgaa tatgctgaaa
       61 gttataatag actagaacag ctagataaag aatttccaga taaactaaaa aaatctattc
      121 ttcaatatgc tatgcaagga aaattagttg aacaagaccc aaatgatgaa tcagtcgaag
      181 ttttacttga aaaaatacga gcagaaaaac aaaaactctt tgaagaaggc aagattaaaa
      241 agaaagattt ggacatttct attgtttccc aaggaga
//
LOCUS       DAVBEO010000116          229 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 009
            SAMEA1678075-rid20185393.denovo.116, whole genome shotgun sequence.
ACCESSION   DAVBEO010000116 DAVBEO010000000
VERSION     DAVBEO010000116.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678075
            Sequence Read Archive: ERR226392
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 229)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 229)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980207.1
            Genome Coverage       :: 150x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:50:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 72 of 147
            Pseudo Genes (incomplete)         :: 72 of 147
            Pseudo Genes (internal stop)      :: 42 of 147
            Pseudo Genes (multiple problems)  :: 32 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..229
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678075-rid20185393.denovo.116"
                     /strain="KS 009"
                     /db_xref="taxon:1313"
     gene            <1..>229
                     /locus_tag="VQ543_002129"
     CDS             <1..>229
                     /locus_tag="VQ543_002129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HET2612759.1"
                     /translation="YTDDEIQVAKLAGKYTTEDGYIFDPRDITSDEGDAYVTPHMTHS
                     HWIKKDSLSEAERAAAQAYAKEKGLTPPSTDH"
BASE COUNT           72 a           49 c           55 g           53 t
ORIGIN      
        1 tacactgatg atgagattca agtagccaag ttggcaggca agtacacaac agaagacggt
       61 tatatctttg atcctcgtga tataaccagt gatgaggggg atgcctatgt aactccacat
      121 atgacccata gccactggat taaaaaagat agtttgtctg aagctgagag agcggcagcc
      181 caggcttatg ctaaagagaa aggtttgacc cctccttcga cagaccatc
//
LOCUS       DAVBEO010000117          204 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 009
            SAMEA1678075-rid20185393.denovo.117, whole genome shotgun sequence.
ACCESSION   DAVBEO010000117 DAVBEO010000000
VERSION     DAVBEO010000117.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678075
            Sequence Read Archive: ERR226392
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 204)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 204)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980207.1
            Genome Coverage       :: 150x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:50:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 72 of 147
            Pseudo Genes (incomplete)         :: 72 of 147
            Pseudo Genes (internal stop)      :: 42 of 147
            Pseudo Genes (multiple problems)  :: 32 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..204
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678075-rid20185393.denovo.117"
                     /strain="KS 009"
                     /db_xref="taxon:1313"
     gene            79..152
                     /locus_tag="VQ543_002130"
     tRNA            79..152
                     /locus_tag="VQ543_002130"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:113..115,aa:Met,seq:cat)
BASE COUNT           47 a           48 c           59 g           50 t
ORIGIN      
        1 gggaacggtc ttgaaaaccg tcaggcgtgt aaaagcgtgc gtgggttcga atcccacatc
       61 ctccttttat attattaacg cgggatggag cagctcggta gctcgtcggg ctcataaccc
      121 gaaggtcgta ggttcaaatc ctgctcccgc aataaggctc ggtagctcag ttggtagagc
      181 aatggattga agctccatgt gtcg
//
LOCUS       DAVBEO010000118          201 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 009
            SAMEA1678075-rid20185393.denovo.118, whole genome shotgun sequence.
ACCESSION   DAVBEO010000118 DAVBEO010000000
VERSION     DAVBEO010000118.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678075
            Sequence Read Archive: ERR226392
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 201)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 201)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980207.1
            Genome Coverage       :: 150x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:50:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 72 of 147
            Pseudo Genes (incomplete)         :: 72 of 147
            Pseudo Genes (internal stop)      :: 42 of 147
            Pseudo Genes (multiple problems)  :: 32 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..201
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678075-rid20185393.denovo.118"
                     /strain="KS 009"
                     /db_xref="taxon:1313"
BASE COUNT           72 a           31 c           29 g           69 t
ORIGIN      
        1 agtaaaatga aataagaaca ggataaatcg atcaggacag tcaaatcgat ttctaacaat
       61 gttttagaag tagaggcgta ctattctagt ttcaatatac tatactatac catattttgt
      121 ttcgcaggga atctattata aaagggtaag tattgcaaaa acacttaccc ttttctttta
      181 tacttcatta agctctactt t
//
